Detailed information for compound 303836

Basic information

Technical information
  • TDR Targets ID: 303836
  • Name: ethyl 2-(1,3-benzothiazol-2-ylamino)-2-phenyl acetate
  • MW: 312.386 | Formula: C17H16N2O2S
  • H donors: 1 H acceptors: 2 LogP: 4.68 Rotable bonds: 6
    Rule of 5 violations (Lipinski): 1
  • SMILES: CCOC(=O)C(c1ccccc1)Nc1nc2c(s1)cccc2
  • InChi: 1S/C17H16N2O2S/c1-2-21-16(20)15(12-8-4-3-5-9-12)19-17-18-13-10-6-7-11-14(13)22-17/h3-11,15H,2H2,1H3,(H,18,19)
  • InChiKey: RXYWYSZTZFGRJL-UHFFFAOYSA-N  


Substructure search Similarity search

Network

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Synonyms

  • ethyl 2-(1,3-benzothiazol-2-ylamino)-2-phenyl-acetate
  • 2-(1,3-benzothiazol-2-ylamino)-2-phenylacetic acid ethyl ester
  • ethyl 2-(1,3-benzothiazol-2-ylamino)-2-phenyl-ethanoate
  • 2-(1,3-benzothiazol-2-ylamino)-2-phenyl-acetic acid ethyl ester

Targets

Known targets for this compound

No curated genes were found associated with this compound

Predicted pathogen targets for this compound

By orthology
No druggable targets predicted by orthology data
By sequence similarity to non orthologous known druggable targets
No druggable targets predicted by sequence similarity
Obtained from network model

Ranking Plot

Putative Targets List

Species Potential target Raw Global Species
Echinococcus granulosus G protein coupled 5 hydroxytryptamine receptor 0.0073 0.1458 0.197
Echinococcus granulosus pyruvate kinase 0.0019 0.0281 0.0377
Mycobacterium ulcerans acyl-CoA synthetase 0.0007 0.0022 0.0069
Entamoeba histolytica Ran family GTPase 0.0021 0.0329 0.1296
Schistosoma mansoni cytochrome P450 0.0008 0.0038 0.0054
Giardia lamblia Cyclin fold protein 1, putative 0.0014 0.0182 0.0715
Leishmania major cytochrome p450-like protein 0.0008 0.0038 0.0148
Loa Loa (eye worm) hypothetical protein 0.0073 0.1458 0.2217
Loa Loa (eye worm) hypothetical protein 0.0026 0.0443 0.0671
Trypanosoma cruzi CYC2-like cyclin, putative 0.0116 0.2392 1
Loa Loa (eye worm) hypothetical protein 0.0073 0.1458 0.2217
Mycobacterium ulcerans acyl-CoA synthetase 0.0024 0.0395 0.2658
Loa Loa (eye worm) STE/STE20/PAKA protein kinase 0.0022 0.0354 0.0535
Brugia malayi G-protein-linked acetylcholine receptor protein 2, putative 0.0073 0.1458 0.3733
Echinococcus multilocularis 0.0008 0.0038 0.0048
Echinococcus multilocularis serotonin receptor 0.0073 0.1458 0.197
Toxoplasma gondii AMP-binding enzyme domain-containing protein 0.0007 0.0022 0.0131
Schistosoma mansoni amine GPCR 0.0073 0.1458 0.2217
Trichomonas vaginalis mitogen-activated protein kinase kinase kinase 3, MAPKKK3, MEKK3, putative 0.0022 0.0354 0.1404
Loa Loa (eye worm) hypothetical protein 0.0018 0.0261 0.0394
Echinococcus granulosus g protein linked acetylcholine receptor gar 2a 0.0073 0.1458 0.197
Mycobacterium ulcerans cytochrome P450 124A1, Cyp124A1 0.0008 0.0038 0.0183
Brugia malayi neuropeptide F receptor 0.0073 0.1458 0.3733
Trichomonas vaginalis conserved hypothetical protein 0.0014 0.0182 0.0676
Loa Loa (eye worm) 5-hydroxytryptamine 2C receptor 0.0073 0.1458 0.2217
Mycobacterium tuberculosis Probable cytochrome P450 138 Cyp138 0.0008 0.0038 0.0038
Echinococcus granulosus neuropeptide receptor 0.0073 0.1458 0.197
Echinococcus multilocularis cyclin dependent kinase 1 0.0049 0.0932 0.1258
Brugia malayi Uncoordinated protein 44 0.0016 0.0215 0.0544
Echinococcus multilocularis pyroglutamylated rfamide peptide receptor 0.0073 0.1458 0.197
Onchocerca volvulus 0.001 0.0082 0.0239
Mycobacterium tuberculosis Possible cytochrome P450 126 Cyp126 0.0008 0.0038 0.0038
Trichomonas vaginalis voltage and ligand gated potassium channel, putative 0.0038 0.0702 0.2869
Trichomonas vaginalis STE family protein kinase 0.0038 0.0694 0.2837
Schistosoma mansoni opsin-like receptor 0.0073 0.1458 0.2217
Mycobacterium ulcerans cytochrome P450 142A3 Cyp142A3 0.0008 0.0038 0.0183
Loa Loa (eye worm) cyclic-nucleotide gated cation channel 0.0008 0.0043 0.0062
Trypanosoma brucei DNA polymerase kappa, putative 0.0021 0.0334 0.1385
Mycobacterium tuberculosis Possible DNA-damage-inducible protein P DinP (DNA polymerase V) (pol IV 2) (DNA nucleotidyltransferase (DNA-directed)) 0.0021 0.0334 0.0334
Onchocerca volvulus 0.0073 0.1453 0.5695
Brugia malayi hypothetical protein 0.0073 0.1458 0.3733
Mycobacterium ulcerans fatty-acid-CoA ligase 0.0018 0.0261 0.1731
Brugia malayi oxidoreductase, short chain dehydrogenase/reductase family protein 0.0007 0.0022 0.0049
Mycobacterium tuberculosis Probable fatty-acid-CoA ligase FadD2 (fatty-acid-CoA synthetase) (fatty-acid-CoA synthase) 0.0024 0.0395 0.0395
Schistosoma mansoni voltage-gated potassium channel 0.0006 0.0007 0.0007
Echinococcus granulosus cdk5 and abl1 enzyme substrate 1 0.0014 0.0182 0.0243
Echinococcus granulosus cyclin y 0.0014 0.0182 0.0243
Trypanosoma brucei DNA polymerase IV, putative 0.0021 0.0334 0.1385
Loa Loa (eye worm) STE/STE20/PAKB protein kinase 0.0016 0.0224 0.0337
Loa Loa (eye worm) intermediate filament tail domain-containing protein 0.0027 0.0454 0.0687
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0073 0.1458 0.2217
Echinococcus multilocularis G protein coupled receptor 139 0.0073 0.1458 0.197
Loa Loa (eye worm) hypothetical protein 0.0073 0.1458 0.2217
Brugia malayi putative neuropeptide receptor 0.0073 0.1458 0.3733
Echinococcus multilocularis beta LACTamase domain containing family member 0.0073 0.1453 0.1962
Mycobacterium tuberculosis Fatty-acid-AMP ligase FadD30 (fatty-acid-AMP synthetase) (fatty-acid-AMP synthase) 0.0018 0.0261 0.0261
Loa Loa (eye worm) hypothetical protein 0.0073 0.1458 0.2217
Echinococcus granulosus COUP TF:Svp nuclear hormone receptor 0.001 0.0082 0.0107
Echinococcus multilocularis lamin dm0 0.0027 0.0454 0.0611
Brugia malayi beta-lactamase 0.0073 0.1453 0.3718
Echinococcus granulosus g protein linked acetylcholine receptor gar 2a 0.0073 0.1458 0.197
Brugia malayi Nuclear hormone receptor family member nhr-14 0.001 0.0082 0.0203
Loa Loa (eye worm) hypothetical protein 0.001 0.0082 0.012
Loa Loa (eye worm) hypothetical protein 0.0073 0.1458 0.2217
Toxoplasma gondii propionate-CoA ligase 0.0007 0.0022 0.0131
Brugia malayi Tachykinin-like peptides receptor 99D 0.0073 0.1458 0.3733
Mycobacterium tuberculosis Possible conserved lipoprotein LpqK 0.0073 0.1453 0.1453
Echinococcus granulosus tachykinin peptides receptor 99D 0.0073 0.1458 0.197
Brugia malayi Serotonin receptor 0.0073 0.1458 0.3733
Brugia malayi G-protein coupled receptor 0.0073 0.1458 0.3733
Entamoeba histolytica pyruvate kinase, putative 0.0026 0.043 0.1724
Schistosoma mansoni protein kinase 0.0038 0.0694 0.1053
Echinococcus granulosus G2:mitotic specific cyclin B3 0.0185 0.3903 0.5277
Echinococcus granulosus cyclin dependent kinase 5 0.0049 0.0932 0.1258
Trichomonas vaginalis cyclin B, putative 0.0116 0.2392 1
Echinococcus granulosus potassium:sodium hyperpolarization activated 0.0008 0.0043 0.0055
Echinococcus multilocularis somatostatin receptor 0.0073 0.1458 0.197
Brugia malayi ecdysteroid receptor 0.001 0.0082 0.0203
Onchocerca volvulus 0.005 0.0968 0.3767
Onchocerca volvulus 0.0014 0.0182 0.0638
Brugia malayi Nuclear hormone receptor family member nhr-49 0.001 0.0082 0.0203
Brugia malayi gonadotropin-releasing hormone receptor 2 0.0073 0.1458 0.3733
Trypanosoma cruzi DNA polymerase kappa, putative 0.0021 0.0334 0.1355
Brugia malayi Dopamine receptor 0.0073 0.1458 0.3733
Brugia malayi Nuclear hormone receptor family member nhr-40 0.001 0.0082 0.0203
Echinococcus granulosus endonuclease reverse transcriptase 0.0013 0.0156 0.0208
Onchocerca volvulus Protein CNPPD1 homolog 0.0014 0.0182 0.0638
Leishmania major DNA polymerase kappa, putative 0.0007 0.0012 0.0038
Echinococcus granulosus dro:myosuppressin receptor 0.0073 0.1458 0.197
Schistosoma mansoni ankyrin 23/unc44 0.0016 0.0215 0.0323
Schistosoma mansoni voltage-gated potassium channel 0.0012 0.0125 0.0187
Loa Loa (eye worm) oxidoreductase 0.0007 0.0022 0.0029
Onchocerca volvulus Pyruvate kinase homolog 0.0037 0.0675 0.26
Schistosoma mansoni ephrin receptor 0.0056 0.1096 0.1664
Schistosoma mansoni biogenic amine (5HT) receptor 0.0073 0.1458 0.2217
Trichomonas vaginalis CMGC family protein kinase 0.0049 0.0932 0.3841
Schistosoma mansoni intermediate filament proteins 0.0027 0.0454 0.0687
Trypanosoma cruzi acetyl-CoA synthetase, putative 0.0007 0.0022 0.0042
Mycobacterium tuberculosis Probable cytochrome P450 140 Cyp140 0.0008 0.0038 0.0038
Trichomonas vaginalis DNA polymerase eta, putative 0.0021 0.0334 0.1319
Echinococcus multilocularis Nuclear hormone receptor family member nhr 41 0.001 0.0082 0.0107
Echinococcus granulosus FTZ F1 alpha 0.001 0.0082 0.0107
Trichomonas vaginalis CMGC family protein kinase 0.0049 0.0932 0.3841
Trichomonas vaginalis D-aminoacylase, putative 0.0073 0.1453 0.6038
Echinococcus multilocularis rhodopsin orphan GPCR 0.0073 0.1458 0.197
Brugia malayi Dopamine receptor protein 2 0.0073 0.1458 0.3733
Brugia malayi hypothetical protein 0.0073 0.1458 0.3733
Plasmodium vivax cysteine repeat modular protein 2, putative 0.0013 0.0156 0.1002
Echinococcus granulosus cyclins 0.006 0.1173 0.1584
Loa Loa (eye worm) hypothetical protein 0.0073 0.1458 0.2217
Entamoeba histolytica cyclin C, putative 0.0014 0.0182 0.0676
Schistosoma mansoni cyclic-nucleotide-gated cation channel 0.0008 0.0043 0.0062
Plasmodium vivax hypothetical protein, conserved 0.0073 0.1453 1
Loa Loa (eye worm) hypothetical protein 0.0073 0.1453 0.2208
Schistosoma mansoni protein kinase 0.0016 0.0224 0.0337
Trypanosoma cruzi long-chain-fatty-acid-CoA ligase, putative 0.0007 0.0022 0.0042
Mycobacterium tuberculosis Cytochrome P450 51 Cyp51 (CYPL1) (P450-L1A1) (sterol 14-alpha demethylase) (lanosterol 14-alpha demethylase) (P450-14DM) 0.0008 0.0038 0.0038
Brugia malayi AMP-binding enzyme family protein 0.0024 0.0395 0.1005
Mycobacterium ulcerans cytochrome P450 108B4 Cyp108B4 0.0008 0.0038 0.0183
Loa Loa (eye worm) hypothetical protein 0.0073 0.1453 0.2208
Brugia malayi acetyl-Coenzyme A synthetase 2 0.0007 0.0022 0.0049
Schistosoma mansoni pyruvate kinase 0.0037 0.0675 0.1024
Mycobacterium ulcerans cytochrome P450 126A3 Cyp126A3 0.0008 0.0038 0.0183
Echinococcus multilocularis tm gpcr rhodopsin gpcr rhodopsin superfamily 0.0073 0.1458 0.197
Trichomonas vaginalis cyclin B, putative 0.0116 0.2392 1
Brugia malayi Cytochrome P450 family protein 0.0008 0.0038 0.0091
Brugia malayi Nuclear hormone receptor family member nhr-3 0.001 0.0082 0.0203
Echinococcus granulosus neuropeptide Y receptor 0.0073 0.1458 0.197
Brugia malayi hypothetical protein 0.0073 0.1458 0.3733
Brugia malayi AMP-binding enzyme family protein 0.0007 0.0022 0.0049
Trichomonas vaginalis penicillin-binding protein, putative 0.0073 0.1453 0.6038
Schistosoma mansoni cyclic-nucleotide-gated cation channel 0.0008 0.0043 0.0062
Leishmania major hypothetical protein, conserved 0.0073 0.1453 0.607
Echinococcus granulosus GTP binding nuclear protein Ran 0.0021 0.0329 0.0441
Mycobacterium ulcerans cytochrome p450 150 cyp150 0.0008 0.0038 0.0183
Mycobacterium tuberculosis Possible fatty-acid-CoA ligase FadD10 (fatty-acid-CoA synthetase) (fatty-acid-CoA synthase) 0.0007 0.0022 0.0022
Trypanosoma cruzi cytochrome p450-like protein, putative 0.0008 0.0038 0.0111
Brugia malayi Cyclin, N-terminal domain containing protein 0.0014 0.0182 0.046
Mycobacterium ulcerans hypothetical protein 0.0073 0.1453 1
Loa Loa (eye worm) hypothetical protein 0.0073 0.1458 0.2217
Mycobacterium tuberculosis Probable peptide synthetase Nrp (peptide synthase) 0.0007 0.0022 0.0022
Leishmania major long-chain-fatty-acid-CoA ligase, putative 0.0007 0.0022 0.008
Brugia malayi Importin beta-1 subunit 0.0029 0.0494 0.1261
Onchocerca volvulus 0.0073 0.1453 0.5695
Mycobacterium ulcerans cytochrome P450 187A5 Cyp187A5 0.0008 0.0038 0.0183
Brugia malayi Cytochrome P450 family protein 0.0008 0.0038 0.0091
Echinococcus granulosus biogenic amine 5HT receptor 0.0073 0.1458 0.197
Echinococcus multilocularis alpha 1A adrenergic receptor 0.0073 0.1458 0.197
Trypanosoma cruzi cdc2-related kinase 1 0.0049 0.0932 0.3867
Echinococcus granulosus rhodopsin orphan GPCR 0.0073 0.1458 0.197
Brugia malayi Cyclin, N-terminal domain containing protein 0.0014 0.0182 0.046
Loa Loa (eye worm) hypothetical protein 0.001 0.0082 0.012
Trypanosoma cruzi cytochrome P450, putative 0.0008 0.0038 0.0111
Mycobacterium tuberculosis Probable medium chain fatty-acid-CoA ligase FadD14 (fatty-acid-CoA synthetase) (fatty-acid-CoA synthase) 0.0007 0.0022 0.0022
Echinococcus multilocularis cyclic nucleotide gated cation channel alpha 3 0.0008 0.0043 0.0055
Toxoplasma gondii cytochrome p450 superfamily protein 0.0008 0.0038 0.0245
Loa Loa (eye worm) hypothetical protein 0.0073 0.1453 0.2208
Leishmania major 4-coumarate:coa ligase-like protein 0.0024 0.0395 0.1641
Schistosoma mansoni amine GPCR 0.0073 0.1458 0.2217
Brugia malayi Protein kinase domain containing protein 0.0049 0.0932 0.2383
Mycobacterium tuberculosis Probable chain -fatty-acid-CoA ligase FadD13 (fatty-acyl-CoA synthetase) 0.0024 0.0395 0.0395
Onchocerca volvulus 0.0073 0.1458 0.5718
Trypanosoma cruzi cytochrome P450, putative 0.0008 0.0038 0.0111
Echinococcus granulosus alpha 1A adrenergic receptor 0.0073 0.1458 0.197
Mycobacterium tuberculosis Probable lipase LipD 0.0073 0.1453 0.1453
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0073 0.1458 0.2217
Brugia malayi RNA, U transporter 1 0.0082 0.1652 0.423
Echinococcus granulosus G protein coupled receptor 139 0.0073 0.1458 0.197
Brugia malayi hypothetical protein 0.0073 0.1458 0.3733
Loa Loa (eye worm) CMGC/CDK/CDC2 protein kinase 0.0049 0.0932 0.1415
Giardia lamblia Kinase, CMGC CDK 0.0049 0.0932 0.3867
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0073 0.1458 0.2217
Echinococcus multilocularis cyclins 0.006 0.1173 0.1584
Mycobacterium ulcerans cytochrome P450 105Q4 Cyp105Q4 0.0008 0.0038 0.0183
Entamoeba histolytica hypothetical protein, conserved 0.0013 0.0156 0.0568
Brugia malayi ephrin receptor 1 precursor 0.0027 0.0453 0.1154
Mycobacterium tuberculosis Probable cytochrome P450 124 Cyp124 0.0008 0.0038 0.0038
Mycobacterium tuberculosis Bifunctional enzyme MbtA: salicyl-AMP ligase (SAL-AMP ligase) + salicyl-S-ArCP synthetase 0.0007 0.0022 0.0022
Brugia malayi AMP-binding enzyme family protein 0.0024 0.0395 0.1005
Echinococcus granulosus neuropeptide Y receptor 0.0073 0.1458 0.197
Brugia malayi Cyclic-nucleotide gated cation channel 0.0008 0.0043 0.0105
Mycobacterium leprae Conserved hypothetical protein 0.0008 0.0038 0.0115
Mycobacterium ulcerans bifunctional enzyme MbtA: salicyl-AMP ligase (SAL-AMP ligase) + salicyl-S-ACP synthetase 0.0007 0.0022 0.0069
Loa Loa (eye worm) cytoplasmic intermediate filament protein 0.0014 0.0181 0.0272
Schistosoma mansoni family S12 unassigned peptidase (S12 family) 0.0073 0.1453 0.2208
Mycobacterium tuberculosis Probable cytochrome P450 139 Cyp139 0.0008 0.0038 0.0038
Echinococcus granulosus cyclin t1 0.0014 0.0182 0.0243
Brugia malayi larval opioid receptor 0.0073 0.1458 0.3733
Echinococcus granulosus Cyclin L1 0.0014 0.0182 0.0243
Mycobacterium ulcerans acyl-CoA synthetase 0.0007 0.0022 0.0069
Loa Loa (eye worm) hypothetical protein 0.0122 0.2535 0.3855
Trypanosoma brucei DNA damage repair protein, putative 0.0007 0.0012 0.0035
Echinococcus granulosus orexin receptor type 2 0.0073 0.1458 0.197
Echinococcus granulosus hyperpolarization activated cyclic 0.0008 0.0043 0.0055
Loa Loa (eye worm) hypothetical protein 0.0056 0.1082 0.1644
Toxoplasma gondii ImpB/MucB/SamB family protein 0.0007 0.0012 0.0063
Mycobacterium ulcerans phenyloxazoline synthase MbtB 0.0007 0.0022 0.0069
Echinococcus granulosus 3'partial|serine:threonine protein kinase PAK 2 0.0016 0.0206 0.0276
Echinococcus granulosus potassium voltage gated channel subfamily H 0.0012 0.0125 0.0166
Echinococcus multilocularis rhodopsin orphan GPCR 0.0073 0.1458 0.197
Trypanosoma brucei cdc2-related kinase 1 0.0049 0.0932 0.3888
Brugia malayi cell division control protein 2 homolog 0.0049 0.0932 0.2383
Trichomonas vaginalis conserved hypothetical protein 0.006 0.1173 0.4859
Plasmodium vivax protein kinase Crk2 0.0049 0.0932 0.6387
Trypanosoma cruzi cyclin 9, putative 0.0014 0.0182 0.0715
Trichomonas vaginalis Importin beta-1 subunit, putative 0.0023 0.0376 0.1494
Toxoplasma gondii cyclin, N-terminal domain-containing protein 0.0014 0.0182 0.1236
Trichomonas vaginalis esterase, putative 0.0073 0.1453 0.6038
Loa Loa (eye worm) nuclear hormone receptor family member nhr-40 0.001 0.0082 0.012
Echinococcus granulosus 5'partial|cyclin dependent kinase 1 0.0049 0.0932 0.1258
Brugia malayi GnHR receptor homolog 0.0073 0.1458 0.3733
Loa Loa (eye worm) hypothetical protein 0.0012 0.0139 0.0208
Brugia malayi Cyclin, N-terminal domain containing protein 0.0014 0.0182 0.046
Schistosoma mansoni tyrosine kinase 0.0016 0.022 0.0331
Plasmodium vivax GTP-binding nuclear protein RAN/TC4, putative 0.0021 0.0329 0.22
Echinococcus multilocularis cyclins 0.006 0.1173 0.1584
Mycobacterium ulcerans non-ribosomal peptide synthetase MbtF 0.0007 0.0022 0.0069
Loa Loa (eye worm) cyclin domain-containing protein 0.0014 0.0182 0.0273
Echinococcus multilocularis COUP TF:Svp nuclear hormone receptor 0.001 0.0082 0.0107
Brugia malayi Cyclin, N-terminal domain containing protein 0.0116 0.2392 0.6125
Trichomonas vaginalis STE family protein kinase 0.0038 0.0694 0.2837
Trypanosoma cruzi Lanosterol 14-alpha demethylase 0.0008 0.0038 0.0111
Loa Loa (eye worm) hypothetical protein 0.0073 0.1458 0.2217
Schistosoma mansoni peptide (FMRFamide/somatostatin)-like receptor 0.0073 0.1458 0.2217
Trichomonas vaginalis conserved hypothetical protein 0.0014 0.0182 0.0676
Onchocerca volvulus Huntingtin homolog 0.0122 0.2535 1
Echinococcus multilocularis orexin receptor type 2 0.0073 0.1458 0.197
Echinococcus multilocularis cytoplasmic intermediate filament protein 0.0013 0.015 0.0199
Echinococcus multilocularis G protein coupled 5 hydroxytryptamine receptor 0.0073 0.1458 0.197
Mycobacterium ulcerans cytochrome P450 144A4 Cyp144A4 0.0008 0.0038 0.0183
Schistosoma mansoni family S12 unassigned peptidase (S12 family) 0.0073 0.1453 0.2208
Loa Loa (eye worm) TYRA-2 protein 0.0073 0.1458 0.2217
Echinococcus multilocularis pyruvate kinase 0.0029 0.0505 0.0679
Brugia malayi Pyruvate kinase, muscle isozyme 0.0037 0.0675 0.1724
Trichomonas vaginalis cyclins, putative 0.0116 0.2392 1
Loa Loa (eye worm) STE/STE20/PAKA protein kinase 0.0022 0.0354 0.0535
Loa Loa (eye worm) hypothetical protein 0.0073 0.1458 0.2217
Chlamydia trachomatis pyruvate kinase 0.0037 0.0675 1
Echinococcus granulosus sex peptide receptor 0.0073 0.1458 0.197
Loa Loa (eye worm) CYL-1 protein 0.0014 0.0182 0.0273
Entamoeba histolytica acyl-CoA synthetase, putative 0.0024 0.0395 0.1574
Echinococcus granulosus p21 activated protein kinase 1 Dpak1 0.0038 0.0694 0.0935
Trichomonas vaginalis cyclin A, putative 0.0014 0.0182 0.0676
Loa Loa (eye worm) hypothetical protein 0.0073 0.1458 0.2217
Schistosoma mansoni serine/threonine protein kinase 0.0049 0.0932 0.1415
Mycobacterium ulcerans cytochrome P450 187A4 Cyp187A4 0.0008 0.0038 0.0183
Loa Loa (eye worm) G-protein coupled receptor 0.0073 0.1458 0.2217
Loa Loa (eye worm) nuclear hormone receptor family member nhr-41 0.001 0.0082 0.012
Trypanosoma cruzi mitotic cyclin, putative 0.0014 0.0182 0.0715
Echinococcus granulosus cyclin B 0.0116 0.2392 0.3232
Mycobacterium ulcerans cytochrome P450 143A3 Cyp143A3 0.0008 0.0038 0.0183
Giardia lamblia Pyruvate kinase 0.0037 0.0675 0.2787
Onchocerca volvulus Bile acid receptor homolog 0.001 0.0082 0.0239
Echinococcus granulosus cytoplasmic intermediate filament protein 0.0013 0.015 0.0199
Echinococcus granulosus 7tm_1 domain containing protein 0.0073 0.1458 0.197
Echinococcus granulosus hyperpolarization activated cyclic 0.0008 0.0043 0.0055
Loa Loa (eye worm) hypothetical protein 0.0014 0.0182 0.0273
Echinococcus multilocularis endonuclease reverse transcriptase 0.0013 0.0156 0.0208
Mycobacterium tuberculosis Probable cytochrome P450 137 Cyp137 0.0008 0.0038 0.0038
Trypanosoma brucei pyruvate kinase 1 0.0037 0.0675 0.2812
Echinococcus multilocularis dna polymerase eta 0.0021 0.0334 0.0449
Mycobacterium leprae Probable pyruvate kinase PykA 0.0037 0.0675 0.4565
Loa Loa (eye worm) hypothetical protein 0.0073 0.1458 0.2217
Echinococcus multilocularis pyruvate kinase 0.0019 0.0281 0.0377
Entamoeba histolytica hypothetical protein 0.0013 0.0156 0.0568
Trypanosoma brucei hypothetical protein, conserved 0.0073 0.1453 0.6069
Schistosoma mansoni cyclin G2 0.0014 0.0182 0.0273
Trypanosoma brucei unspecified product 0.0021 0.0334 0.1385
Giardia lamblia Pyruvate kinase 0.0019 0.0281 0.1133
Plasmodium vivax cysteine repeat modular protein 1, putative 0.0013 0.0156 0.1002
Schistosoma mansoni serine/threonine protein kinase 0.0049 0.0932 0.1415
Plasmodium falciparum pyruvate kinase 0.0037 0.0675 0.5744
Loa Loa (eye worm) cyclin domain-containing protein 0.0014 0.0182 0.0273
Echinococcus multilocularis oligomeric golgi complex subunit 3 0.0014 0.0182 0.0243
Trichomonas vaginalis cyclins, putative 0.0116 0.2392 1
Brugia malayi RE15519p 0.0073 0.1458 0.3733
Toxoplasma gondii cyclin 4, putative 0.0014 0.0182 0.1236
Brugia malayi Nuclear hormone receptor family member nhr-31 0.001 0.0082 0.0203
Toxoplasma gondii Acetyl-coenzyme A synthetase 2, putative 0.0007 0.0022 0.0131
Brugia malayi AKH receptor 0.0073 0.1458 0.3733
Schistosoma mansoni hypothetical protein 0.0016 0.0206 0.031
Plasmodium falciparum cysteine repeat modular protein 3 0.0013 0.0156 0.1312
Schistosoma mansoni nuclear hormone receptor nor-1/nor-2 0.001 0.0082 0.012
Onchocerca volvulus 0.0073 0.1458 0.5718
Loa Loa (eye worm) hypothetical protein 0.0073 0.1458 0.2217
Onchocerca volvulus 0.0073 0.1458 0.5718
Loa Loa (eye worm) unidentified vitellogenin-linked transcript protein 6 0.0073 0.1458 0.2217
Echinococcus granulosus g protein coupled receptor 0.0073 0.1458 0.197
Giardia lamblia GTP-binding nuclear protein RAN/TC4 0.0021 0.0329 0.1332
Mycobacterium leprae putative cytochrome p450 0.0008 0.0038 0.0115
Mycobacterium tuberculosis Probable fatty-acid-CoA ligase FadD3 (fatty-acid-CoA synthetase) (fatty-acid-CoA synthase) 0.0017 0.024 0.024
Echinococcus granulosus cyclin dependent kinase 1 0.0049 0.0932 0.1258
Schistosoma mansoni cyclin B3 0.0185 0.3903 0.5939
Trypanosoma cruzi mitotic cyclin, putative 0.0014 0.0182 0.0715
Mycobacterium ulcerans peptide synthetase Nrp (peptide synthase) 0.0007 0.0022 0.0069
Brugia malayi intermediate filament protein 0.0027 0.0454 0.1157
Brugia malayi Dopamine receptor protein 1, putative (partial) 0.0073 0.1458 0.3733
Echinococcus granulosus cyclins 0.006 0.1173 0.1584
Echinococcus multilocularis dro:myosuppressin receptor 0.0073 0.1458 0.197
Brugia malayi hypothetical protein 0.0073 0.1458 0.3733
Trichomonas vaginalis DNA polymerase IV / kappa, putative 0.0021 0.0334 0.1319
Plasmodium falciparum pyruvate kinase 2 0.0019 0.0281 0.2382
Entamoeba histolytica p21-activated kinase 0.0038 0.0694 0.2837
Trypanosoma brucei DNA polymerase kappa, putative 0.0021 0.0334 0.1385
Giardia lamblia G2/mitotic-specific cyclin B 0.0116 0.2392 1
Echinococcus multilocularis pyruvate kinase 0.0019 0.0281 0.0377
Entamoeba histolytica cell division protein kinase 2, putative 0.0049 0.0932 0.3841
Schistosoma mansoni serine/threonine protein kinase 0.0022 0.0354 0.0535
Echinococcus multilocularis thyroid hormone receptor alpha 0.001 0.0082 0.0107
Mycobacterium ulcerans long-chain-fatty-acid-CoA ligase 0.0024 0.0395 0.2658
Toxoplasma gondii pyruvate kinase PyK1 0.0037 0.0675 0.4636
Echinococcus granulosus rhodopsin orphan GPCR 0.0073 0.1458 0.197
Echinococcus multilocularis nuclear receptor 2DBD gamma 0.001 0.0082 0.0107
Mycobacterium ulcerans O-succinylbenzoic acid--CoA ligase 0.0007 0.0022 0.0069
Loa Loa (eye worm) hypothetical protein 0.0073 0.1458 0.2217
Trichomonas vaginalis cyclin B, putative 0.006 0.1173 0.4859
Trypanosoma brucei long-chain-fatty-acid-CoA ligase, putative 0.0007 0.0022 0.0077
Echinococcus multilocularis biogenic amine (5HT) receptor 0.0073 0.1458 0.197
Onchocerca volvulus 0.0027 0.0454 0.172
Schistosoma mansoni thyroid hormone receptor 0.001 0.0082 0.012
Mycobacterium ulcerans cytochrome P450 185A4 Cyp185A4 0.0008 0.0038 0.0183
Loa Loa (eye worm) hypothetical protein 0.0073 0.1458 0.2217
Echinococcus granulosus voltage gated potassium channel 0.0012 0.0125 0.0166
Echinococcus multilocularis cyclins 0.006 0.1173 0.1584
Echinococcus granulosus peptide allatostatin:somatostatin 0.0073 0.1458 0.197
Schistosoma mansoni biogenic amine (dopamine) receptor 0.0073 0.1458 0.2217
Trichomonas vaginalis importin beta-1, putative 0.0023 0.0376 0.1494
Echinococcus multilocularis neuropeptide Y receptor 0.0073 0.1458 0.197
Leishmania major cytochrome p450-like protein 0.0008 0.0038 0.0148
Onchocerca volvulus Pyruvate kinase homolog 0.0037 0.0675 0.26
Schistosoma mansoni amine GPCR 0.0073 0.1458 0.2217
Toxoplasma gondii GCC2 and GCC3 domain-containing protein 0.0013 0.0156 0.1059
Schistosoma mansoni nuclear receptor 2DBD-gamma 0.001 0.0082 0.012
Loa Loa (eye worm) pyruvate kinase 0.0037 0.0675 0.1024
Loa Loa (eye worm) hypothetical protein 0.0073 0.1458 0.2217
Loa Loa (eye worm) pyruvate kinase-PB 0.0026 0.043 0.0651
Schistosoma mansoni Cyclin fold protein 0.0014 0.0182 0.0273
Trichomonas vaginalis cyclins, putative 0.0116 0.2392 1
Toxoplasma gondii GTP-binding nuclear protein ran/tc4 0.0021 0.0329 0.2249
Onchocerca volvulus 0.0073 0.1458 0.5718
Loa Loa (eye worm) nuclear Hormone Receptor family member 0.001 0.0082 0.012
Loa Loa (eye worm) beta-lactamase 0.0073 0.1453 0.2208
Echinococcus multilocularis FTZ F1 alpha 0.001 0.0082 0.0107
Echinococcus granulosus tumor protein p63 0.0345 0.7393 1
Schistosoma mansoni photoreceptor-specific nuclear receptor related 0.001 0.0082 0.012
Brugia malayi Ligand-binding domain of nuclear hormone receptor family protein 0.001 0.0082 0.0203
Echinococcus multilocularis netrin receptor unc 5 0.0016 0.0215 0.0287
Mycobacterium tuberculosis Probable fatty-acid-CoA ligase FadD35 (fatty-acid-CoA synthetase) (fatty-acid-CoA synthase) 0.0017 0.024 0.024
Loa Loa (eye worm) neuropeptide F receptor 0.0073 0.1458 0.2217
Trypanosoma cruzi cdc2-related kinase 3 0.0049 0.0932 0.3867
Schistosoma mansoni hypothetical protein 0.0073 0.1458 0.2217
Brugia malayi hypothetical protein 0.0014 0.0182 0.046
Loa Loa (eye worm) hypothetical protein 0.0073 0.1458 0.2217
Mycobacterium tuberculosis Probable fatty-acid-CoA ligase FadD5 (fatty-acid-CoA synthetase) (fatty-acid-CoA synthase) 0.0017 0.024 0.024
Schistosoma mansoni biogenic amine (dopamine) receptor 0.0073 0.1458 0.2217
Echinococcus granulosus intermediate filament protein 0.0027 0.0454 0.0611
Echinococcus granulosus dna polymerase eta 0.0021 0.0334 0.0449
Echinococcus multilocularis Ankyrin 0.0016 0.0218 0.0291
Entamoeba histolytica cyclin, putative 0.0116 0.2392 1
Mycobacterium tuberculosis Probable cytochrome P450 128 Cyp128 0.0008 0.0038 0.0038
Loa Loa (eye worm) hypothetical protein 0.0073 0.1458 0.2217
Mycobacterium tuberculosis Probable cytochrome P450 132 Cyp132 0.0008 0.0038 0.0038
Echinococcus multilocularis G1:S specific cyclin D1 0.0014 0.0182 0.0243
Leishmania major cell division protein kinase 2,cdc2-related kinase 0.0049 0.0932 0.389
Echinococcus multilocularis cyclin t1 0.0014 0.0182 0.0243
Trypanosoma brucei DNA polymerase kappa, putative 0.0021 0.0334 0.1385
Loa Loa (eye worm) nuclear hormone receptor family member nhr-14 0.001 0.0082 0.012
Onchocerca volvulus Neuropeptide F receptor homolog 0.0073 0.1458 0.5718
Brugia malayi neuropeptide F receptor 0.0073 0.1458 0.3733
Echinococcus multilocularis rhodopsin orphan GPCR 0.0073 0.1458 0.197
Plasmodium falciparum cyclin 0.006 0.1173 1
Loa Loa (eye worm) beta-LACTamase domain containing family member 0.0073 0.1453 0.2208
Trypanosoma cruzi importin beta-1 subunit, putative 0.0023 0.0376 0.153
Entamoeba histolytica cyclin, domain containing protein 0.0014 0.0182 0.0676
Brugia malayi pyruvate kinase, muscle isozyme 0.0008 0.0037 0.0088
Mycobacterium ulcerans beta-lactamase 0.0073 0.1453 1
Plasmodium falciparum acetyl-CoA synthetase, putative 0.0007 0.0022 0.0162
Trypanosoma brucei cyclin dependent kinase-binding protein, putative 0.0014 0.0182 0.0747
Loa Loa (eye worm) hypothetical protein 0.0012 0.0139 0.0208
Loa Loa (eye worm) G-protein coupled receptor 0.0073 0.1458 0.2217
Mycobacterium leprae Probable lipase LipE 0.0073 0.1453 1
Entamoeba histolytica protein kinase, putative 0.0016 0.0224 0.0855
Echinococcus granulosus nuclear factor of activated T cells 5 0.0082 0.1651 0.223
Brugia malayi follicle stimulating hormone receptor 0.0073 0.1458 0.3733
Brugia malayi hypothetical protein 0.0073 0.1458 0.3733
Loa Loa (eye worm) hypothetical protein 0.0007 0.0022 0.0029
Brugia malayi putative neuropeptide receptor NPR1 0.0073 0.1458 0.3733
Echinococcus granulosus neuropeptide s receptor 0.0073 0.1458 0.197
Brugia malayi Cytochrome P450 family protein 0.0008 0.0038 0.0091
Loa Loa (eye worm) hypothetical protein 0.0073 0.1458 0.2217
Loa Loa (eye worm) hypothetical protein 0.0073 0.1458 0.2217
Trichomonas vaginalis CMGC family protein kinase 0.0049 0.0932 0.3841
Schistosoma mansoni hypothetical protein 0.0073 0.1458 0.2217
Trypanosoma brucei DNA polymerase kappa, putative 0.0015 0.0189 0.0778
Schistosoma mansoni biogenic amine (5HT) receptor 0.0073 0.1458 0.2217
Echinococcus granulosus cyclic nucleotide gated cation channel 0.0008 0.0043 0.0055
Loa Loa (eye worm) hypothetical protein 0.0073 0.1458 0.2217
Trypanosoma brucei DNA polymerase kappa, putative 0.0015 0.0189 0.0778
Schistosoma mansoni growth hormone secretagogue receptor 0.0073 0.1458 0.2217
Loa Loa (eye worm) cytochrome P450 0.0008 0.0038 0.0054
Entamoeba histolytica hypothetical protein 0.0013 0.0156 0.0568
Mycobacterium ulcerans pyruvate kinase 0.0037 0.0675 0.4602
Trichomonas vaginalis cyclins, putative 0.0116 0.2392 1
Loa Loa (eye worm) hypothetical protein 0.0122 0.2535 0.3855
Trypanosoma brucei cyclin 9 0.0014 0.0182 0.0747
Echinococcus multilocularis nuclear receptor 2DBD gamma 0.001 0.0082 0.0107
Mycobacterium tuberculosis Possible fatty-acid-CoA ligase FadD1 (fatty-acid-CoA synthetase) (fatty-acid-CoA synthase) 0.0007 0.0022 0.0022
Entamoeba histolytica protein kinase, putative 0.0038 0.0694 0.2837
Echinococcus multilocularis musashi 0.0027 0.0454 0.0611
Echinococcus granulosus lamin dm0 0.0027 0.0454 0.0611
Brugia malayi Steroid receptor seven-up type 2 0.001 0.0082 0.0203
Echinococcus granulosus g-protein coupled receptor 0.0073 0.1458 0.197
Echinococcus multilocularis cyclin 0.0014 0.0182 0.0243
Echinococcus granulosus nuclear receptor 2DBD gamma 0.001 0.0082 0.0107
Trichomonas vaginalis ran, putative 0.0021 0.0329 0.1296
Entamoeba histolytica acyl-coA synthetase, putative 0.0024 0.0395 0.1574
Onchocerca volvulus Protein ultraspiracle homolog 0.001 0.0082 0.0239
Brugia malayi P21-Rho-binding domain containing protein 0.0016 0.0206 0.0522
Brugia malayi Cyclin, N-terminal domain containing protein 0.0014 0.0182 0.046
Loa Loa (eye worm) cyclin C 0.0014 0.0182 0.0273
Brugia malayi photoreceptor-specific nuclear receptor 0.001 0.0082 0.0203
Schistosoma mansoni hyperpolarization activated cyclic nucleotide-gated potassium channel 0.0008 0.0043 0.0062
Schistosoma mansoni RAR-like nuclear receptor 0.001 0.0082 0.012
Mycobacterium tuberculosis Phenyloxazoline synthase MbtB (phenyloxazoline synthetase) 0.0007 0.0022 0.0022
Trypanosoma cruzi pyruvate kinase 2, putative 0.0037 0.0675 0.2787
Giardia lamblia Hypothetical protein 0.006 0.1173 0.488
Schistosoma mansoni hyperpolarization activated cyclic nucleotide-gated potassium channel 0.0008 0.0043 0.0062
Mycobacterium tuberculosis Peptide synthetase MbtF (peptide synthase) 0.0007 0.0022 0.0022
Schistosoma mansoni netrin receptor unc5 0.0016 0.0215 0.0323
Loa Loa (eye worm) hypothetical protein 0.0073 0.1458 0.2217
Echinococcus multilocularis neuropeptides capa receptor 0.0073 0.1458 0.197
Loa Loa (eye worm) hypothetical protein 0.0073 0.1458 0.2217
Brugia malayi Voltage-gated potassium channel, HERG (KCNH2)-related. C. elegans unc-103 ortholog 0.0041 0.076 0.1943
Brugia malayi pyruvate kinase 0.0008 0.0037 0.0088
Loa Loa (eye worm) hypothetical protein 0.0073 0.1458 0.2217
Echinococcus granulosus rhodopsin orphan GPCR 0.0073 0.1458 0.197
Trichomonas vaginalis cyclin D, putative 0.006 0.1173 0.4859
Echinococcus granulosus cyclin dependent kinase 0.0049 0.0932 0.1258
Trypanosoma brucei importin beta-1 subunit, putative 0.0029 0.0494 0.2057
Echinococcus granulosus 7TM GPCR rhodopsin 0.0073 0.1458 0.197
Echinococcus granulosus cytochrome P450 2K1 0.0008 0.0038 0.0048
Mycobacterium ulcerans long-chain fatty-acid CoA ligase 0.0024 0.0395 0.2658
Brugia malayi Nuclear hormone receptor family member nhr-25 0.001 0.0082 0.0203
Schistosoma mansoni hypothetical protein 0.0073 0.1458 0.2217
Plasmodium vivax pyruvate kinase, putative 0.0037 0.0675 0.4602
Schistosoma mansoni peptide (allatostatin)-like receptor 0.0073 0.1458 0.2217
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0073 0.1458 0.2217
Plasmodium vivax acetyl-CoA synthetase, putative 0.0007 0.0022 0.0069
Schistosoma mansoni g1/s-specific cyclin C 0.0014 0.0182 0.0273
Trichomonas vaginalis conserved hypothetical protein 0.0037 0.0676 0.2761
Entamoeba histolytica cysteine-rich surface protein, putative 0.0013 0.0156 0.0568
Brugia malayi cyclin fold protein 1 variant b 0.0014 0.0182 0.046
Onchocerca volvulus 0.0073 0.1453 0.5695
Loa Loa (eye worm) cyclin domain-containing protein 0.0014 0.0182 0.0273
Toxoplasma gondii hypothetical protein 0.0013 0.0156 0.1059
Onchocerca volvulus 0.0116 0.2392 0.9431
Leishmania major DNA polymerase kappa, putative,DNA polymerase IV, putative 0.0021 0.0334 0.1388
Schistosoma mansoni biogenic amine (octopamine/dopamine) receptor 0.0073 0.1458 0.2217
Brugia malayi hypothetical protein 0.0073 0.1458 0.3733
Trichomonas vaginalis STE family protein kinase 0.0038 0.0694 0.2837
Schistosoma mansoni thyrotropin-releasing hormone receptor 0.0073 0.1458 0.2217
Loa Loa (eye worm) hypothetical protein 0.0073 0.1458 0.2217
Brugia malayi GCC2 and GCC3 family protein 0.0013 0.0156 0.0394
Mycobacterium tuberculosis Probable cytochrome P450 monooxygenase 142 Cyp142 0.0008 0.0038 0.0038
Giardia lamblia Kinase, CMGC CDK 0.0049 0.0932 0.3867
Brugia malayi Pyruvate kinase, alpha/beta domain containing protein 0.0011 0.0111 0.0278
Echinococcus granulosus cyclins 0.006 0.1173 0.1584
Onchocerca volvulus Dopamine\/Ecdysteroid receptor homolog 0.0073 0.1458 0.5718
Loa Loa (eye worm) hypothetical protein 0.0073 0.1458 0.2217
Echinococcus multilocularis dna polymerase kappa 0.0021 0.0334 0.0449
Toxoplasma gondii BRCA1 C Terminus (BRCT) domain-containing protein 0.0007 0.0012 0.0063
Schistosoma mansoni amine GPCR 0.0073 0.1458 0.2217
Echinococcus granulosus rhodopsin orphan GPCR 0.0073 0.1458 0.197
Trypanosoma cruzi acetyl-CoA synthetase, putative 0.0007 0.0022 0.0042
Trichomonas vaginalis STE family protein kinase 0.0038 0.0694 0.2837
Echinococcus granulosus pyruvate kinase 0.0019 0.0281 0.0377
Mycobacterium ulcerans cytochrome P450 143A4 Cyp143A4 0.0008 0.0038 0.0183
Schistosoma mansoni hypothetical protein 0.0016 0.0215 0.0323
Plasmodium falciparum cysteine repeat modular protein 2 0.0013 0.0156 0.1312
Schistosoma mansoni thyroid hormone receptor 0.001 0.0082 0.012
Plasmodium falciparum protein kinase 5 0.0049 0.0932 0.794
Schistosoma mansoni neuropeptide F-like receptor 0.0073 0.1458 0.2217
Mycobacterium ulcerans cytochrome P450 123A3 Cyp123A3 0.0008 0.0038 0.0183
Plasmodium falciparum cysteine repeat modular protein 4 0.0013 0.0156 0.1312
Echinococcus multilocularis potassium:sodium hyperpolarization activated 0.0008 0.0043 0.0055
Echinococcus multilocularis neuropeptide s receptor 0.0073 0.1458 0.197
Loa Loa (eye worm) hypothetical protein 0.0013 0.015 0.0224
Echinococcus multilocularis cyclin dependent kinase 5 0.0049 0.0932 0.1258
Toxoplasma gondii cyclin dependent kinase binding protein 0.0014 0.0182 0.1236
Trichomonas vaginalis cyclin D, putative 0.0014 0.0182 0.0676
Echinococcus multilocularis cyclin y 0.0014 0.0182 0.0243
Schistosoma mansoni hypothetical protein 0.0013 0.0156 0.0234
Schistosoma mansoni hypothetical protein 0.0307 0.657 1
Giardia lamblia Hypothetical protein 0.0013 0.0156 0.0607
Schistosoma mansoni biogenic amine receptor 0.0073 0.1458 0.2217
Schistosoma mansoni hypothetical protein 0.0016 0.0206 0.031
Echinococcus granulosus neuropeptides capa receptor 0.0073 0.1458 0.197
Trichomonas vaginalis cyclin B, putative 0.0014 0.0182 0.0676
Echinococcus granulosus neuropeptide FF receptor 2 0.0073 0.1458 0.197
Trichomonas vaginalis conserved hypothetical protein 0.0014 0.0182 0.0676
Echinococcus multilocularis pyruvate kinase 0.0037 0.0675 0.091
Mycobacterium tuberculosis Probable esterase LipL 0.0073 0.1453 0.1453
Brugia malayi Hypothetical 52.5 kDa protein ZK945.1 in chromosome II, putative 0.0073 0.1453 0.3718
Mycobacterium tuberculosis Probable lipase LipE 0.0073 0.1453 0.1453
Loa Loa (eye worm) hypothetical protein 0.0024 0.0395 0.0597
Schistosoma mansoni importin beta-1 0.0029 0.0494 0.0749
Echinococcus granulosus cyclic nucleotide gated cation channel 0.0008 0.0043 0.0055
Echinococcus granulosus neuropeptide receptor 0.0073 0.1458 0.197
Schistosoma mansoni ran 0.0021 0.0329 0.0497
Brugia malayi Cyclin, N-terminal domain containing protein 0.0014 0.0182 0.046
Brugia malayi ImpB/MucB/SamB family protein 0.0021 0.0334 0.085
Echinococcus multilocularis importin subunit beta 1 0.0029 0.0494 0.0666
Onchocerca volvulus Pyruvate kinase homolog 0.0037 0.0675 0.26
Echinococcus granulosus death domain containing protein 0.0016 0.0215 0.0287
Leishmania major DNA polymerase eta, putative 0.0021 0.0334 0.1388
Trypanosoma cruzi DNA polymerase kappa, putative 0.0021 0.0334 0.1355
Onchocerca volvulus 0.0073 0.1458 0.5718
Echinococcus multilocularis pyruvate kinase 0.0037 0.0675 0.091
Echinococcus granulosus importin subunit beta 1 0.0029 0.0494 0.0666
Loa Loa (eye worm) hypothetical protein 0.0016 0.0218 0.0328
Brugia malayi Nuclear hormone receptor family member nhr-1 0.001 0.0082 0.0203
Echinococcus multilocularis 7TM GPCR, rhodopsin 0.0073 0.1458 0.197
Onchocerca volvulus 0.0073 0.1458 0.5718
Toxoplasma gondii hypothetical protein 0.0045 0.0858 0.5898
Brugia malayi Nuclear hormone receptor family member nhr-19 0.001 0.0082 0.0203
Loa Loa (eye worm) pyruvate kinase 0.0037 0.0675 0.1024
Trichomonas vaginalis cyclin B, putative 0.0014 0.0182 0.0676
Trichomonas vaginalis voltage and ligand gated potassium channel, putative 0.0038 0.0702 0.2869
Trypanosoma brucei DNA polymerase IV, putative 0.0021 0.0334 0.1385
Entamoeba histolytica cyclin family protein 0.006 0.1173 0.4859
Mycobacterium leprae conserved hypothetical protein 0.0073 0.1453 1
Entamoeba histolytica hypothetical protein 0.0014 0.0182 0.0676
Mycobacterium ulcerans cytochrome P450 125A7 Cyp125A7 0.0008 0.0038 0.0183
Brugia malayi GTP-binding nuclear protein RAN/TC4 0.0021 0.0329 0.0836
Echinococcus granulosus neuropeptide receptor A26 0.0073 0.1458 0.197
Loa Loa (eye worm) hypothetical protein 0.0018 0.0261 0.0394
Echinococcus granulosus serine:threonine protein kinase PAK 1 0.0022 0.0336 0.0451
Echinococcus granulosus dna polymerase kappa 0.0021 0.0334 0.0449
Leishmania major importin beta-1 subunit, putative 0.0023 0.0376 0.1562
Leishmania major CYC2-like cyclin, putative,cyclin 6, putative 0.0116 0.2392 1
Schistosoma mansoni voltage-gated potassium channel 0.0012 0.0125 0.0187
Echinococcus granulosus ephrin type A receptor 4 A 0.007 0.1385 0.1871
Schistosoma mansoni nuclear hormone receptor 0.001 0.0082 0.012
Entamoeba histolytica hypothetical protein 0.0016 0.0206 0.0779
Loa Loa (eye worm) hypothetical protein 0.0073 0.1458 0.2217
Echinococcus granulosus rhodopsin orphan GPCR 0.0073 0.1458 0.197
Loa Loa (eye worm) hypothetical protein 0.0024 0.0395 0.0597
Loa Loa (eye worm) hypothetical protein 0.0037 0.0675 0.1024
Giardia lamblia Hypothetical protein 0.0014 0.0182 0.0715
Onchocerca volvulus Steroid hormone receptor family member cnr14 homolog 0.001 0.0082 0.0239
Loa Loa (eye worm) hypothetical protein 0.0026 0.043 0.0651
Brugia malayi AMP-binding enzyme family protein 0.0024 0.0395 0.1005
Plasmodium vivax hypothetical protein, conserved 0.0014 0.0182 0.1181
Brugia malayi ORL1-like opioid receptor 0.0073 0.1458 0.3733
Schistosoma mansoni opsin-like receptor 0.0073 0.1458 0.2217
Mycobacterium ulcerans acyl-CoA synthetase 0.0007 0.0022 0.0069
Trypanosoma brucei DNA polymerase kappa, putative 0.0021 0.0334 0.1385
Schistosoma mansoni hypothetical protein 0.0014 0.0182 0.0273
Loa Loa (eye worm) hypothetical protein 0.0028 0.0485 0.0735
Loa Loa (eye worm) cyclin domain-containing protein 0.0185 0.3903 0.5939
Loa Loa (eye worm) hypothetical protein 0.0073 0.1458 0.2217
Entamoeba histolytica acyl-CoA synthetase, putative 0.0024 0.0395 0.1574
Trichomonas vaginalis cyclin D, putative 0.006 0.1173 0.4859
Loa Loa (eye worm) hypothetical protein 0.0012 0.0125 0.0187
Echinococcus multilocularis potassium voltage gated channel subfamily H 0.0012 0.0125 0.0166
Brugia malayi nuclear hormone receptor 0.001 0.0082 0.0203
Echinococcus multilocularis rhodopsin orphan GPCR 0.0073 0.1458 0.197
Toxoplasma gondii ABC1 family protein 0.0073 0.1453 1
Brugia malayi cytoplasmic intermediate filament protein 0.0014 0.0181 0.0458
Mycobacterium ulcerans hypothetical protein 0.0024 0.0395 0.2658
Brugia malayi G protein-coupled receptor F59B2.13 0.0073 0.1458 0.3733
Mycobacterium tuberculosis Possible cytochrome P450 135A1 Cyp135A1 0.0008 0.0038 0.0038
Trypanosoma brucei mitotic cyclin 6 0.0116 0.2392 1
Trichomonas vaginalis cyclins, putative 0.0014 0.0182 0.0676
Loa Loa (eye worm) hypothetical protein 0.0073 0.1458 0.2217
Schistosoma mansoni opsin-like receptor 0.0073 0.1458 0.2217
Plasmodium vivax cyclin homologue, putative 0.0014 0.0182 0.1181
Echinococcus granulosus pyruvate kinase 0.0037 0.0675 0.091
Loa Loa (eye worm) nuclear hormone receptor family member nhr-49 0.001 0.0082 0.012
Trypanosoma cruzi hypothetical protein, conserved 0.0073 0.1453 0.6055
Mycobacterium tuberculosis Probable hydrolase 0.0073 0.1453 0.1453
Trypanosoma brucei DNA polymerase kappa, putative 0.0021 0.0334 0.1385
Loa Loa (eye worm) hypothetical protein 0.0073 0.1458 0.2217
Brugia malayi cytochrome P450 0.0008 0.0038 0.0091
Brugia malayi beta-lactamase family protein 0.0073 0.1453 0.3718
Brugia malayi Death domain containing protein 0.0016 0.0215 0.0544
Loa Loa (eye worm) hypothetical protein 0.0073 0.1458 0.2217
Brugia malayi Melatonin receptor type 1A 0.0073 0.1458 0.3733
Brugia malayi hypothetical protein 0.0122 0.2535 0.6492
Echinococcus multilocularis cyclin k 0.0014 0.0182 0.0243
Mycobacterium ulcerans acyl-CoA synthetase 0.0007 0.0022 0.0069
Mycobacterium tuberculosis Conserved protein 0.0073 0.1453 0.1453
Giardia lamblia CEGP1 protein 0.0013 0.0156 0.0607
Brugia malayi Serotonin/octopamine receptor family protein 7 0.0073 0.1458 0.3733
Trypanosoma brucei cdc2-related kinase 3 0.0049 0.0932 0.3888
Schistosoma mansoni DNA polymerase IV / kappa 0.0007 0.0012 0.0014
Trypanosoma brucei cyclin 3 0.0014 0.0182 0.0747
Leishmania major pyruvate kinase 0.0037 0.0675 0.2814
Brugia malayi Nuclear hormone receptor family member nhr-41 0.001 0.0082 0.0203
Brugia malayi hypothetical protein 0.0014 0.0182 0.046
Giardia lamblia Cyclin B-like protein 0.0014 0.0182 0.0715
Echinococcus granulosus Ankyrin 0.0016 0.0218 0.0291
Loa Loa (eye worm) hypothetical protein 0.0073 0.1458 0.2217
Plasmodium falciparum DNA repair protein REV1, putative 0.0007 0.0012 0.0078
Onchocerca volvulus Huntingtin homolog 0.0122 0.2535 1
Entamoeba histolytica protein kinase, putative 0.0014 0.0174 0.0644
Schistosoma mansoni neuropeptide receptor 0.0073 0.1458 0.2217
Echinococcus multilocularis cyclin B3 1 0.006 0.1173 0.1584
Loa Loa (eye worm) hypothetical protein 0.0014 0.0182 0.0273
Onchocerca volvulus 0.0027 0.0454 0.172
Brugia malayi Voltage-gated potassium channel, EAG (KCNH1)-related. C. elegans egl-2 ortholog 0.0012 0.0125 0.0315
Brugia malayi AMP-binding enzyme family protein 0.0007 0.0022 0.0049
Loa Loa (eye worm) hypothetical protein 0.0029 0.0494 0.0749
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0073 0.1458 0.2217
Brugia malayi Protein kinase domain 0.0038 0.0694 0.1772
Loa Loa (eye worm) follicle stimulating hormone receptor 0.0073 0.1458 0.2217
Echinococcus granulosus pyruvate kinase 0.0019 0.0281 0.0377
Mycobacterium ulcerans DNA polymerase IV 0.0021 0.0334 0.2238
Schistosoma mansoni terminal deoxycytidyl transferase 0.0021 0.0334 0.0505
Trichomonas vaginalis pyruvate kinase, putative 0.0037 0.0675 0.2756
Echinococcus multilocularis tm gpcr rhodopsin gpcr rhodopsin superfamily 0.0073 0.1458 0.197
Echinococcus granulosus rhodopsin orphan GPCR 0.0073 0.1458 0.197
Trichomonas vaginalis cyclins, putative 0.0014 0.0182 0.0676
Schistosoma mansoni cyclin d 0.0014 0.0182 0.0273
Schistosoma mansoni biogenic amine receptor 0.0073 0.1458 0.2217
Trypanosoma brucei DNA polymerase kappa, putative 0.0021 0.0334 0.1385
Echinococcus multilocularis g protein linked acetylcholine receptor gar 2a 0.0073 0.1458 0.197
Echinococcus multilocularis cyclic nucleotide gated cation channel 0.0008 0.0043 0.0055
Echinococcus multilocularis serine:threonine protein kinase PAK 3 0.0038 0.0694 0.0935
Brugia malayi GCC2 and GCC3 family protein 0.0013 0.0156 0.0394
Loa Loa (eye worm) steroid hormone receptor 0.001 0.0082 0.012
Echinococcus multilocularis cyclin A3 4 0.0014 0.0182 0.0243
Schistosoma mansoni adenoreceptor 0.0073 0.1458 0.2217
Echinococcus granulosus thyrotropin releasing hormone receptor 0.0073 0.1458 0.197
Trichomonas vaginalis pyruvate kinase, putative 0.0037 0.0675 0.2756
Echinococcus multilocularis ecdysone induced protein 78C 0.001 0.0082 0.0107
Loa Loa (eye worm) AMP-binding enzyme family protein 0.0007 0.0022 0.0029
Onchocerca volvulus 0.0056 0.1082 0.422
Echinococcus granulosus ecdysone induced protein 78C 0.001 0.0082 0.0107
Mycobacterium ulcerans fatty-acid-CoA ligase 0.0024 0.0395 0.2658
Mycobacterium leprae PROBABLE FATTY-ACID-CoA LIGASE FADD7 (FATTY-ACID-CoA SYNTHETASE) (FATTY-ACID-CoA SYNTHASE) 0.0024 0.0395 0.2607
Schistosoma mansoni voltage-gated potassium channel 0.0045 0.0842 0.1279
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0073 0.1458 0.2217
Trypanosoma brucei DNA polymerase eta, putative 0.0021 0.0334 0.1385
Echinococcus multilocularis neuropeptide receptor 0.0073 0.1458 0.197
Echinococcus multilocularis cyclin dependent kinase 0.0049 0.0932 0.1258
Loa Loa (eye worm) hypothetical protein 0.0073 0.1458 0.2217
Echinococcus granulosus cyclin b3 0.006 0.1173 0.1584
Brugia malayi hypothetical protein 0.0073 0.1458 0.3733
Mycobacterium ulcerans non-ribosomal peptide synthetase MbtE 0.0007 0.0022 0.0069
Schistosoma mansoni proteasome subunit alpha 1 (T01 family) 0.0014 0.0182 0.0273
Mycobacterium ulcerans acyl-CoA synthetase 0.0024 0.0395 0.2658
Loa Loa (eye worm) hypothetical protein 0.0116 0.2392 0.3637
Trichomonas vaginalis voltage and ligand gated potassium channel, putative 0.0008 0.0043 0.0092
Trypanosoma brucei unspecified product 0.0015 0.0189 0.0778
Loa Loa (eye worm) hypothetical protein 0.0016 0.0215 0.0323
Loa Loa (eye worm) hypothetical protein 0.0008 0.0043 0.0062
Mycobacterium tuberculosis Probable cytochrome P450 143 Cyp143 0.0008 0.0038 0.0038
Brugia malayi sulfakinin receptor protein 0.0073 0.1458 0.3733
Leishmania major cyclin 9, putative 0.0014 0.0182 0.075
Schistosoma mansoni voltage-gated potassium channel 0.0008 0.0043 0.0062
Echinococcus granulosus fmrfamide receptor 0.0073 0.1458 0.197
Onchocerca volvulus Cyclin L homolog 0.0014 0.0182 0.0638
Echinococcus granulosus cyclins 0.006 0.1173 0.1584
Echinococcus multilocularis hyperpolarization activated cyclic 0.0008 0.0043 0.0055
Schistosoma mansoni pyruvate kinase 0.0037 0.0675 0.1024
Schistosoma mansoni DNA polymerase eta 0.0021 0.0334 0.0505
Schistosoma mansoni retinoic acid receptor RXR 0.001 0.0082 0.012
Schistosoma mansoni lamin 0.0027 0.0454 0.0687
Leishmania major 4-coumarate:coa ligase-like protein 0.0024 0.0395 0.1641
Schistosoma mansoni peptide (FMRFamide/neurokinin-3)-like receptor 0.0073 0.1458 0.2217
Echinococcus multilocularis cyclin B 0.0116 0.2392 0.3232
Trypanosoma brucei hypothetical protein, conserved 0.0007 0.0012 0.0035
Brugia malayi hypothetical protein 0.0073 0.1458 0.3733
Echinococcus granulosus pyruvate kinase 0.0037 0.0675 0.091
Loa Loa (eye worm) P21-Rho-binding domain-containing protein 0.0016 0.0206 0.031
Trypanosoma cruzi hypothetical protein, conserved 0.0073 0.1453 0.6055
Leishmania major DNA polymerase kappa, putative 0.0021 0.0334 0.1388
Echinococcus granulosus lamin 0.0027 0.0454 0.0611
Onchocerca volvulus Cyclin L homolog 0.0014 0.0182 0.0638
Schistosoma mansoni coup transcription factor 0.001 0.0082 0.012
Echinococcus multilocularis voltage gated potassium channel 0.0012 0.0125 0.0166
Echinococcus multilocularis cyclins 0.006 0.1173 0.1584
Loa Loa (eye worm) AMP-binding enzyme family protein 0.0007 0.0022 0.0029
Echinococcus granulosus cyclins 0.0014 0.0182 0.0243
Leishmania major 4-coumarate:coa ligase-like protein 0.0024 0.0395 0.1641
Echinococcus multilocularis neuropeptide Y receptor 0.0073 0.1458 0.197
Echinococcus granulosus cyclin G2 0.0014 0.0182 0.0243
Echinococcus multilocularis pyruvate kinase 0.0019 0.0281 0.0377
Leishmania major DNA damage repair protein, putative 0.0007 0.0012 0.0038
Echinococcus granulosus snurportin 1 0.0307 0.657 0.8886
Mycobacterium tuberculosis Probable fatty-acid-CoA ligase FadD7 (fatty-acid-CoA synthetase) (fatty-acid-CoA synthase) 0.0017 0.024 0.024
Echinococcus granulosus cyclin B3 1 0.006 0.1173 0.1584
Echinococcus granulosus cyclin y 0.0014 0.0182 0.0243
Trypanosoma brucei pyruvate kinase 1, putative 0.0037 0.0675 0.2812
Echinococcus multilocularis rhodopsin orphan GPCR 0.0073 0.1458 0.197
Entamoeba histolytica hypothetical protein 0.0023 0.0376 0.1494
Echinococcus multilocularis growth hormone secretagogue receptor type 1 0.0073 0.1458 0.197
Plasmodium falciparum cysteine repeat modular protein 1 0.0013 0.0156 0.1312
Brugia malayi serine/threonine-protein kinase PAK 7 0.0016 0.0224 0.0568
Echinococcus granulosus ankyrin repeat and death domain containing protein 0.0016 0.0215 0.0287
Mycobacterium tuberculosis P-hydroxybenzoyl-AMP ligase FadD22 0.0007 0.0022 0.0022
Loa Loa (eye worm) cyclin domain-containing protein 0.0014 0.0182 0.0273
Echinococcus multilocularis G-protein coupled receptor, putative 0.0073 0.1458 0.197
Plasmodium vivax pyruvate kinase 2, putative 0.0019 0.0281 0.1872
Echinococcus granulosus hepatocyte nuclear factor 4 alpha 0.001 0.0082 0.0107
Leishmania major acetyl-CoA synthetase, putative 0.0007 0.0022 0.008
Echinococcus granulosus retinoic acid receptor rxr beta a 0.001 0.0082 0.0107
Mycobacterium tuberculosis Probable pyruvate kinase PykA 0.0037 0.0675 0.0675
Echinococcus granulosus neuropeptides capa receptor 0.0073 0.1458 0.197
Echinococcus granulosus cyclin A3 4 0.0014 0.0182 0.0243
Brugia malayi P21-Rho-binding domain containing protein 0.0016 0.0206 0.0522
Echinococcus multilocularis fmrfamide receptor 0.0073 0.1458 0.197
Mycobacterium ulcerans cytochrome P450 191A3 Cyp191A3 0.0008 0.0038 0.0183
Echinococcus granulosus G1:S specific cyclin D1 0.0014 0.0182 0.0243
Schistosoma mansoni hypothetical protein 0.0073 0.1458 0.2217
Brugia malayi GCC2 and GCC3 family protein 0.0013 0.0156 0.0394
Trypanosoma brucei Lanosterol 14-alpha demethylase 0.0008 0.0038 0.0145
Echinococcus granulosus cyclic nucleotide gated cation channel alpha 3 0.0008 0.0043 0.0055
Onchocerca volvulus 0.0073 0.1458 0.5718
Schistosoma mansoni cyclin l 0.0014 0.0182 0.0273
Loa Loa (eye worm) voltage and ligand gated potassium channel 0.0041 0.076 0.1154
Toxoplasma gondii HEAT repeat-containing protein 0.0029 0.0494 0.3392
Echinococcus multilocularis cyclin dependent kinase 1 0.0049 0.0932 0.1258
Schistosoma mansoni serine/threonine protein kinase 0.0022 0.0354 0.0535
Schistosoma mansoni cyclins 0.006 0.1173 0.1782
Loa Loa (eye worm) hypothetical protein 0.0073 0.1458 0.2217
Schistosoma mansoni histamine h1 receptor 0.0073 0.1458 0.2217
Echinococcus granulosus serine:threonine protein kinase PAK 3 0.0038 0.0694 0.0935
Entamoeba histolytica cyclin, putative 0.006 0.1173 0.4859
Trypanosoma cruzi DNA polymerase eta, putative 0.0021 0.0334 0.1355
Mycobacterium ulcerans cytochrome P450 150A6 Cyp150A6 0.0008 0.0038 0.0183
Mycobacterium tuberculosis Probable fatty-acid-CoA ligase FadD8 (fatty-acid-CoA synthetase) (fatty-acid-CoA synthase) 0.0007 0.0022 0.0022
Mycobacterium tuberculosis Conserved protein 0.0073 0.1453 0.1453
Mycobacterium ulcerans cytochrome P450 136A2 Cyp136A2 0.0008 0.0038 0.0183
Brugia malayi Cyclin, N-terminal domain containing protein 0.0116 0.2392 0.6125
Mycobacterium tuberculosis Cytochrome P450 121 Cyp121 0.0008 0.0038 0.0038
Schistosoma mansoni amine GPCR 0.0073 0.1458 0.2217
Mycobacterium ulcerans acyl-CoA synthetase 0.0007 0.0022 0.0069
Trypanosoma brucei acetyl-CoA synthetase, putative 0.0007 0.0022 0.0077
Entamoeba histolytica protein kinase, putative 0.0016 0.0224 0.0855
Loa Loa (eye worm) hypothetical protein 0.0073 0.1458 0.2217
Brugia malayi steroid hormone receptor 0.001 0.0082 0.0203
Trypanosoma cruzi cyclin, putative 0.0116 0.2392 1
Echinococcus multilocularis serine:threonine protein kinase PAK 3 0.0038 0.0694 0.0935
Mycobacterium ulcerans fusion of enoyl-CoA hydratase, EchA21 and lipase, LipE 0.0073 0.1453 1
Trichomonas vaginalis cyclin B, putative 0.0116 0.2392 1
Schistosoma mansoni protein kinase 0.0016 0.0206 0.031
Echinococcus granulosus rhodopsin orphan GPCR 0.0073 0.1458 0.197
Schistosoma mansoni alpha-1 adrenergic receptor 0.0073 0.1458 0.2217
Echinococcus multilocularis PAK box P21 Rho binding 0.0016 0.0206 0.0276
Loa Loa (eye worm) hypothetical protein 0.0013 0.0156 0.0234
Trypanosoma brucei mitotic cyclin 0.0014 0.0182 0.0747
Trypanosoma brucei DNA polymerase kappa, putative 0.0021 0.0334 0.1385
Mycobacterium ulcerans acyl-CoA synthetase 0.0024 0.0395 0.2658
Loa Loa (eye worm) nucleolar RNA-associated protein alpha 0.0307 0.657 1
Loa Loa (eye worm) CMGC/CDK/CDK5 protein kinase 0.0049 0.0932 0.1415
Loa Loa (eye worm) hypothetical protein 0.0013 0.0156 0.0234
Echinococcus multilocularis rhodopsin orphan GPCR 0.0073 0.1458 0.197
Echinococcus multilocularis sex peptide receptor 0.0073 0.1458 0.197
Brugia malayi Protein kinase domain containing protein 0.0017 0.0233 0.0591
Brugia malayi G protein-coupled receptor 0.0073 0.1458 0.3733
Echinococcus granulosus neural Wiskott Aldrich syndrome protein 0.0016 0.0206 0.0276
Brugia malayi Unidentified vitellogenin-linked transcript protein 6, putative 0.0073 0.1458 0.3733
Echinococcus granulosus somatostatin receptor 0.0073 0.1458 0.197
Entamoeba histolytica cyclin, domain containing protein 0.0014 0.0182 0.0676
Echinococcus multilocularis g-protein coupled receptor 0.0073 0.1458 0.197
Echinococcus multilocularis potassium voltage gated channel subfamily H 0.0041 0.076 0.1025
Mycobacterium ulcerans long-chain-acyl-CoA synthetase 0.0007 0.0022 0.0069
Echinococcus granulosus g protein coupled receptor 0.0073 0.1458 0.197
Loa Loa (eye worm) cyclin fold protein 1 variant b 0.0014 0.0182 0.0273
Brugia malayi Dopamine receptor protein 1 0.0073 0.1458 0.3733
Echinococcus granulosus nuclear receptor 2DBD gamma 0.001 0.0082 0.0107
Schistosoma mansoni pyruvate kinase 0.0019 0.0281 0.0425
Echinococcus multilocularis hepatocyte nuclear factor 4 alpha 0.001 0.0082 0.0107
Mycobacterium tuberculosis Probable cytochrome P450 130 Cyp130 0.0008 0.0038 0.0038
Echinococcus granulosus Nuclear hormone receptor family member nhr 41 0.001 0.0082 0.0107
Brugia malayi WH1 domain containing protein 0.0016 0.0206 0.0522
Schistosoma mansoni retinoid-x-receptor (RXR) 0.001 0.0082 0.012
Trichomonas vaginalis cyclin A, putative 0.0116 0.2392 1
Schistosoma mansoni cellular tumor antigen P53 0.005 0.0968 0.147
Mycobacterium tuberculosis Peptide synthetase MbtE (peptide synthase) 0.0007 0.0022 0.0022
Loa Loa (eye worm) hypothetical protein 0.001 0.0082 0.012
Schistosoma mansoni biogenic amine receptor 0.0073 0.1458 0.2217
Trichomonas vaginalis penicillin-binding protein, putative 0.0073 0.1453 0.6038
Leishmania major cell division related protein kinase 2,cdc2-related kinase 0.0049 0.0932 0.389
Plasmodium falciparum cyclin 1 0.0014 0.0182 0.1531
Schistosoma mansoni Tr4/Tr2 (homologue) 0.001 0.0082 0.012
Plasmodium vivax hypothetical protein, conserved 0.0013 0.0156 0.1002
Loa Loa (eye worm) cytochrome P450 family protein 0.0008 0.0038 0.0054
Brugia malayi Nuclear hormone receptor family member nhr-25 0.001 0.0082 0.0203
Trichomonas vaginalis D-aminoacylase, putative 0.0073 0.1453 0.6038
Schistosoma mansoni neuropeptide receptor 0.0073 0.1458 0.2217
Giardia lamblia Cyclin A 0.006 0.1173 0.488
Mycobacterium tuberculosis Probable cytochrome P450 141 Cyp141 0.0008 0.0038 0.0038
Echinococcus multilocularis cyclins 0.006 0.1173 0.1584
Onchocerca volvulus 0.0073 0.1458 0.5718
Mycobacterium tuberculosis Probable cytochrome P450 144 Cyp144 0.0008 0.0038 0.0038
Brugia malayi Intermediate filament tail domain containing protein 0.0027 0.0454 0.1157
Schistosoma mansoni myosin xvIII 0.0073 0.1458 0.2217
Loa Loa (eye worm) hypothetical protein 0.0073 0.1458 0.2217
Echinococcus granulosus hypothetical protein 0.0073 0.1458 0.197
Echinococcus multilocularis ankyrin repeat and death domain containing protein 0.0016 0.0215 0.0287
Mycobacterium ulcerans cytochrome P450 189A7 Cyp189A7 0.0008 0.0038 0.0183
Loa Loa (eye worm) nuclear hormone receptor family member nhr-31 0.001 0.0082 0.012
Echinococcus multilocularis g protein coupled receptor 0.0073 0.1458 0.197
Brugia malayi G-protein coupled receptor 0.0073 0.1458 0.3733
Brugia malayi nuclear receptor NHR-88 0.001 0.0082 0.0203
Echinococcus multilocularis neural Wiskott Aldrich syndrome protein 0.0016 0.0206 0.0276
Loa Loa (eye worm) pyruvate kinase 0.0008 0.0037 0.0052
Echinococcus granulosus potassium voltage gated channel subfamily H 0.0041 0.076 0.1025
Loa Loa (eye worm) hypothetical protein 0.0073 0.1453 0.2208
Brugia malayi Cyclin, N-terminal domain containing protein 0.0185 0.3903 1
Schistosoma mansoni peptide (allatostatin/somatostatin)-like receptor 0.0073 0.1458 0.2217
Echinococcus multilocularis cdk5 and abl1 enzyme substrate 1 0.0014 0.0182 0.0243
Echinococcus multilocularis cyclins 0.006 0.1173 0.1584
Brugia malayi beta-lactamase family protein 0.0073 0.1453 0.3718
Schistosoma mansoni peptide (FMRFamide/somatostatin)-like receptor 0.0073 0.1458 0.2217
Loa Loa (eye worm) GTP-binding nuclear protein RAN/TC4 0.0021 0.0329 0.0497
Loa Loa (eye worm) hypothetical protein 0.0018 0.0261 0.0394
Schistosoma mansoni neuropeptide f receptor 76f 0.0073 0.1458 0.2217
Echinococcus multilocularis rhodopsin orphan GPCR 0.0073 0.1458 0.197
Plasmodium vivax hypothetical protein, conserved 0.0013 0.0156 0.1002
Brugia malayi Cyclin, N-terminal domain containing protein 0.0014 0.0182 0.046
Echinococcus granulosus biogenic amine 5HT receptor 0.0073 0.1458 0.197
Echinococcus granulosus pyroglutamylated rfamide peptide receptor 0.0073 0.1458 0.197
Onchocerca volvulus 0.0073 0.1458 0.5718
Echinococcus granulosus tm gpcr rhodopsin 0.0073 0.1458 0.197
Mycobacterium ulcerans DNA polymerase IV 0.0021 0.0334 0.2238
Loa Loa (eye worm) hypothetical protein 0.001 0.0082 0.012
Echinococcus multilocularis g protein coupled receptor 0.0073 0.1458 0.197
Onchocerca volvulus 0.0073 0.1458 0.5718
Brugia malayi ImpB/MucB/SamB family protein 0.0021 0.0334 0.085
Plasmodium vivax cyclin dependent kinase binding protein, putative 0.0014 0.0182 0.1181
Loa Loa (eye worm) nuclear hormone receptor family member nhr-1 0.001 0.0082 0.012
Echinococcus granulosus cyclin 0.0014 0.0182 0.0243
Mycobacterium ulcerans long-chain-fatty-acid--CoA ligase 0.0024 0.0395 0.2658
Echinococcus multilocularis PAK box P21 Rho binding 0.0016 0.0224 0.03
Brugia malayi Nuclear hormone receptor-like 1 0.001 0.0082 0.0203
Leishmania major cytochrome p450-like protein 0.0008 0.0038 0.0148
Mycobacterium tuberculosis Probable conserved lipoprotein 0.0073 0.1453 0.1453
Leishmania major pyruvate kinase 0.0037 0.0675 0.2814
Echinococcus multilocularis cyclins 0.006 0.1173 0.1584
Trypanosoma cruzi cdc2-related kinase 3 0.0049 0.0932 0.3867
Trypanosoma cruzi hypothetical protein, conserved 0.0014 0.0182 0.0715
Loa Loa (eye worm) hypothetical protein 0.0073 0.1458 0.2217
Echinococcus multilocularis cyclin y 0.0014 0.0182 0.0243
Echinococcus multilocularis hyperpolarization activated cyclic 0.0008 0.0043 0.0055
Loa Loa (eye worm) hypothetical protein 0.0021 0.0334 0.0505
Loa Loa (eye worm) CYP4Cod1 0.0008 0.0038 0.0054
Trichomonas vaginalis cyclins, putative 0.006 0.1173 0.4859
Loa Loa (eye worm) hypothetical protein 0.0073 0.1458 0.2217
Loa Loa (eye worm) hypothetical protein 0.0073 0.1458 0.2217
Echinococcus multilocularis snurportin 1 0.0307 0.657 0.8886
Loa Loa (eye worm) hypothetical protein 0.0018 0.0261 0.0394
Echinococcus multilocularis neuropeptide receptor A26 0.0073 0.1458 0.197
Loa Loa (eye worm) ImpB/MucB/SamB family protein 0.0021 0.0334 0.0505
Loa Loa (eye worm) hypothetical protein 0.005 0.0968 0.147
Onchocerca volvulus 0.0073 0.1458 0.5718
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0073 0.1458 0.2217
Schistosoma mansoni hypothetical protein 0.0014 0.0182 0.0273
Trypanosoma cruzi cyclin, putative 0.0116 0.2392 1
Echinococcus multilocularis tm gpcr rhodopsin gpcr rhodopsin superfamily 0.0073 0.1458 0.197
Echinococcus multilocularis FTZ F1 nuclear receptor protein 0.001 0.0082 0.0107
Loa Loa (eye worm) hypothetical protein 0.0013 0.0156 0.0234
Echinococcus granulosus oligomeric golgi complex subunit 3 0.0014 0.0182 0.0243
Echinococcus granulosus tm gpcr rhodopsin 0.0073 0.1458 0.197
Schistosoma mansoni protein kinase 0.0038 0.0694 0.1053
Loa Loa (eye worm) gonadotropin-releasing hormone receptor 2 0.0073 0.1458 0.2217
Schistosoma mansoni biogenic amine (dopamine) receptor 0.0073 0.1458 0.2217
Schistosoma mansoni cyclic-nucleotide-gated cation channel 0.0008 0.0043 0.0062
Echinococcus multilocularis allatostatin A receptor 0.0073 0.1458 0.197
Onchocerca volvulus 0.0013 0.0156 0.0535
Mycobacterium tuberculosis Probable cytochrome P450 136 Cyp136 0.0008 0.0038 0.0038
Schistosoma mansoni neuropeptide receptor 0.0073 0.1458 0.2217
Plasmodium vivax importin-beta 2, putative 0.0029 0.0494 0.3351
Loa Loa (eye worm) hypothetical protein 0.0073 0.1458 0.2217
Plasmodium falciparum cyclin dependent kinase binding protein, putative 0.0014 0.0182 0.1531
Trichomonas vaginalis STE family protein kinase 0.0016 0.0224 0.0855
Leishmania major acetyl-CoA synthetase, putative 0.0007 0.0022 0.008
Trypanosoma brucei DNA polymerase kappa, putative 0.0007 0.0012 0.0035
Giardia lamblia Hypothetical protein 0.0014 0.0182 0.0715
Trypanosoma brucei GTP-binding nuclear protein rtb2, putative 0.0021 0.0329 0.1362
Mycobacterium tuberculosis Possible cytochrome P450 135B1 Cyp135B1 0.0008 0.0038 0.0038
Onchocerca volvulus 0.0073 0.1458 0.5718
Mycobacterium ulcerans acyl-CoA synthetase 0.0007 0.0022 0.0069
Mycobacterium ulcerans esterase/lipase LipP 0.0073 0.1453 1
Loa Loa (eye worm) hypothetical protein 0.0027 0.0454 0.0687
Echinococcus multilocularis neuropeptides capa receptor 0.0073 0.1458 0.197
Echinococcus multilocularis tumor protein p63 0.0345 0.7393 1
Mycobacterium tuberculosis Probable cytochrome P450 125 Cyp125 0.0008 0.0038 0.0038
Entamoeba histolytica deoxycytidyl transferase, putative 0.0021 0.0334 0.1319
Echinococcus granulosus netrin receptor unc 5 0.0016 0.0215 0.0287
Loa Loa (eye worm) hypothetical protein 0.0048 0.0914 0.1388
Echinococcus granulosus serotonin receptor 0.0073 0.1458 0.197
Brugia malayi p21/Cdc42/Rac1-activated kinase 0.0022 0.0354 0.0902
Loa Loa (eye worm) hypothetical protein 0.0073 0.1458 0.2217
Schistosoma mansoni steroid hormone receptor ad4bp 0.001 0.0082 0.012
Schistosoma mansoni muscarinic acetylcholine (GAR) receptor 0.0073 0.1458 0.2217
Schistosoma mansoni serine/threonine protein kinase 0.0016 0.022 0.0331
Plasmodium falciparum importin beta, putative 0.0029 0.0494 0.4203
Onchocerca volvulus 0.0073 0.1458 0.5718
Brugia malayi Ligand-binding domain of nuclear hormone receptor family protein 0.001 0.0082 0.0203
Echinococcus granulosus acetyl coenzyme A synthetase cytoplasmic 0.0007 0.0022 0.0026
Leishmania major cyclin 0.0116 0.2392 1
Entamoeba histolytica protein kinase, putative 0.0016 0.0224 0.0855
Leishmania major GTP-binding protein, putative 0.0021 0.0329 0.1365
Schistosoma mansoni wiskott-aldrich syndrome protein 0.0016 0.0206 0.031
Schistosoma mansoni histamine-responsive GPCR (AAF21638) 0.0073 0.1458 0.2217
Loa Loa (eye worm) cytochrome P450 family protein 0.0008 0.0038 0.0054
Plasmodium vivax cysteine repeat modular protein 3, putative 0.0013 0.0156 0.1002
Loa Loa (eye worm) hypothetical protein 0.0036 0.0642 0.0974
Trypanosoma brucei chrX additional, unordered contigs 0.0007 0.0012 0.0035
Onchocerca volvulus 0.0073 0.1458 0.5718
Loa Loa (eye worm) hypothetical protein 0.0013 0.0156 0.0234
Mycobacterium tuberculosis Probable cytochrome P450 123 Cyp123 0.0008 0.0038 0.0038
Toxoplasma gondii kringle domain-containing protein 0.0013 0.0156 0.1059
Schistosoma mansoni neuropeptide F-like receptor 0.0073 0.1458 0.2217
Brugia malayi GCC2 and GCC3 family protein 0.0013 0.0156 0.0394
Loa Loa (eye worm) hypothetical protein 0.0037 0.0676 0.1025
Leishmania major DNA polymerase eta, putative 0.0007 0.0012 0.0038
Loa Loa (eye worm) intermediate filament protein 0.0027 0.0454 0.0687
Loa Loa (eye worm) melatonin receptor type 1A 0.0073 0.1458 0.2217
Trypanosoma cruzi STE/STE20 serine/threonine-protein kinase, putative 0.0022 0.0354 0.1439
Schistosoma mansoni hypothetical protein 0.0008 0.0038 0.0054
Echinococcus multilocularis cyclin G2 0.0014 0.0182 0.0243
Echinococcus granulosus growth hormone secretagogue receptor type 1 0.0073 0.1458 0.197
Loa Loa (eye worm) hypothetical protein 0.0116 0.2392 0.3637
Toxoplasma gondii cyclin domain protein, cyclin H family protein 0.0014 0.0182 0.1236
Toxoplasma gondii pyruvate kinase PyKII 0.0019 0.0281 0.1923
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0073 0.1458 0.2217
Loa Loa (eye worm) hypothetical protein 0.001 0.0082 0.012
Trypanosoma brucei DNA polymerase kappa, putative 0.0021 0.0334 0.1385
Loa Loa (eye worm) G-protein-linked acetylcholine receptor protein 2 0.0073 0.1458 0.2217
Schistosoma mansoni retinoblastoma-binding protein 4 (rbbp4) 0.0016 0.0218 0.0328
Loa Loa (eye worm) hypothetical protein 0.0073 0.1453 0.2208
Echinococcus granulosus PAK box P21 Rho binding 0.0016 0.0206 0.0276
Mycobacterium ulcerans cytochrome P450 140A5 Cyp140A5 0.0008 0.0038 0.0183
Loa Loa (eye worm) cytochrome P450 family protein 0.0008 0.0038 0.0054
Trypanosoma brucei DNA polymerase kappa, putative 0.0007 0.0012 0.0035
Trichomonas vaginalis cyclin B3, putative 0.006 0.1173 0.4859
Echinococcus multilocularis lamin 0.0027 0.0454 0.0611
Toxoplasma gondii ImpB/MucB/SamB family protein 0.0007 0.0012 0.0063
Giardia lamblia Kinase, STE STE20 0.0038 0.0694 0.2867
Echinococcus granulosus terminal deoxycytidyl transferase rev1 0.0021 0.0334 0.0449
Loa Loa (eye worm) hypothetical protein 0.001 0.0082 0.012
Brugia malayi polk-prov protein 0.0007 0.0012 0.0023
Toxoplasma gondii hypothetical protein 0.0014 0.0182 0.1236
Echinococcus multilocularis terminal deoxycytidyl transferase rev1 0.0021 0.0334 0.0449
Loa Loa (eye worm) cyclin domain-containing protein 0.0014 0.0182 0.0273
Trichomonas vaginalis cyclin B, putative 0.0116 0.2392 1
Schistosoma mansoni ran 0.0021 0.0329 0.0497
Onchocerca volvulus 0.0073 0.1458 0.5718
Trypanosoma brucei DNA polymerase IV, putative 0.0021 0.0334 0.1385
Plasmodium falciparum acyl-CoA synthetase 0.0018 0.0261 0.2209
Mycobacterium ulcerans long-chain-fatty-acid--CoA ligase 0.0007 0.0022 0.0069
Schistosoma mansoni voltage-gated potassium channel 0.0045 0.0842 0.1279
Mycobacterium ulcerans acyl-CoA synthetase 0.0007 0.0022 0.0069
Onchocerca volvulus 0.0073 0.1458 0.5718
Onchocerca volvulus 0.0073 0.1458 0.5718
Loa Loa (eye worm) CMGC/CDK/CDC2 protein kinase 0.0049 0.0932 0.1415
Loa Loa (eye worm) hypothetical protein 0.001 0.0082 0.012
Loa Loa (eye worm) pyruvate kinase 0.0037 0.0675 0.1024
Loa Loa (eye worm) hypothetical protein 0.0073 0.1458 0.2217
Echinococcus multilocularis g protein coupled receptor 0.0073 0.1458 0.197
Loa Loa (eye worm) cyclic-nucleotide gated cation channel 0.0008 0.0043 0.0062
Toxoplasma gondii cell-cycle-associated protein kinase CDK, putative 0.0049 0.0932 0.6409
Mycobacterium tuberculosis Probable esterase/lipase LipP 0.0073 0.1453 0.1453
Echinococcus multilocularis fmrfamide receptor 0.0073 0.1458 0.197
Mycobacterium ulcerans cytochrome P450 188A3 Cyp188A3 0.0008 0.0038 0.0183
Trichomonas vaginalis conserved hypothetical protein 0.0014 0.0182 0.0676
Brugia malayi AMP-binding enzyme family protein 0.0007 0.0022 0.0049
Plasmodium falciparum GTP-binding nuclear protein RAN/TC4 0.0021 0.0329 0.2786
Echinococcus multilocularis Cyclin L1 0.0014 0.0182 0.0243
Brugia malayi Cytochrome P450 family protein 0.0008 0.0038 0.0091
Schistosoma mansoni ancient conserved domain protein 2 (cyclin m2) 0.0073 0.1458 0.2217
Plasmodium falciparum conserved Plasmodium protein, unknown function 0.0014 0.0182 0.1531
Brugia malayi Nuclear hormone receptor family member nhr-19 0.001 0.0082 0.0203
Loa Loa (eye worm) hypothetical protein 0.0018 0.0261 0.0394
Mycobacterium ulcerans acyl-CoA synthetase 0.0007 0.0022 0.0069
Loa Loa (eye worm) hypothetical protein 0.0073 0.1458 0.2217
Entamoeba histolytica cell division protein kinase 2, putative 0.0049 0.0932 0.3841
Brugia malayi Cyclin, N-terminal domain containing protein 0.0014 0.0182 0.046
Loa Loa (eye worm) cyclin domain-containing protein 0.0014 0.0182 0.0273
Trichomonas vaginalis D-aminoacylase, putative 0.0073 0.1453 0.6038
Entamoeba histolytica hypothetical protein 0.0016 0.0206 0.0779
Echinococcus granulosus cyclin k 0.0014 0.0182 0.0243
Schistosoma mansoni cyclin k 0.0014 0.0182 0.0273
Echinococcus granulosus allatostatin A receptor 0.0073 0.1458 0.197
Schistosoma mansoni FTZ-F1 nuclear receptor-like protein 0.001 0.0082 0.012
Mycobacterium leprae PROBABLE FATTY-ACID-CoA LIGASE FADD2 (FATTY-ACID-CoA SYNTHETASE) (FATTY-ACID-CoA SYNTHASE) 0.0024 0.0395 0.2607
Echinococcus granulosus tm gpcr rhodopsin 0.0073 0.1458 0.197
Schistosoma mansoni 60S ribosomal protein L21 0.0006 0.0007 0.0007
Echinococcus multilocularis neuropeptide FF receptor 2 0.0073 0.1458 0.197
Loa Loa (eye worm) hypothetical protein 0.0073 0.1458 0.2217
Leishmania major mitotic cyclin, putative 0.0014 0.0182 0.075
Echinococcus multilocularis tachykinin peptides receptor 99D 0.0073 0.1458 0.197
Brugia malayi Pyruvate kinase, M2 isozyme 0.0037 0.0675 0.1724
Loa Loa (eye worm) hypothetical protein 0.0073 0.1458 0.2217
Echinococcus multilocularis neuropeptide receptor 0.0073 0.1458 0.197
Trypanosoma cruzi cyclin 6, putative 0.0116 0.2392 1
Trypanosoma brucei cytochrome P450, putative 0.0008 0.0038 0.0145
Onchocerca volvulus 0.0013 0.0156 0.0535
Plasmodium vivax cyclin 4, putative 0.0014 0.0182 0.1181
Mycobacterium tuberculosis Conserved hypothetical protein 0.0021 0.0334 0.0334
Echinococcus multilocularis G2:mitotic specific cyclin B3 0.0185 0.3903 0.5277
Loa Loa (eye worm) hypothetical protein 0.001 0.0082 0.012
Loa Loa (eye worm) neuropeptide F receptor 0.0073 0.1458 0.2217
Echinococcus multilocularis acetyl coenzyme A synthetase, cytoplasmic 0.0007 0.0022 0.0026
Trypanosoma brucei DNA polymerase kappa, putative 0.0021 0.0334 0.1385
Loa Loa (eye worm) immunoglobulin I-set domain-containing protein 0.0016 0.0215 0.0323
Brugia malayi hypothetical protein 0.0073 0.1458 0.3733
Echinococcus granulosus cyclins 0.006 0.1173 0.1584
Trypanosoma cruzi GTP-binding nuclear protein rtb2, putative 0.0021 0.0329 0.1332
Trichomonas vaginalis Importin beta-1 subunit, putative 0.0023 0.0376 0.1494
Mycobacterium tuberculosis Fatty-acid-CoA synthetase FadD17 (fatty-acid-CoA synthase) (fatty-acid-CoA ligase) 0.0007 0.0022 0.0022
Schistosoma mansoni neuropeptide receptor 0.0073 0.1458 0.2217
Echinococcus multilocularis cyclin b3 0.006 0.1173 0.1584
Loa Loa (eye worm) hypothetical protein 0.0024 0.0395 0.0597
Brugia malayi Cyclin C 0.0014 0.0182 0.046
Loa Loa (eye worm) hypothetical protein 0.0056 0.1085 0.1648
Echinococcus multilocularis GTP binding nuclear protein Ran 0.0021 0.0329 0.0441
Onchocerca volvulus 0.0024 0.0395 0.1485
Echinococcus multilocularis thyrotropin releasing hormone receptor 0.0073 0.1458 0.197
Trichomonas vaginalis cyclin B3, putative 0.0014 0.0182 0.0676
Trichomonas vaginalis cyclins, putative 0.007 0.14 0.5818
Trypanosoma cruzi long-chain-fatty-acid-CoA ligase, putative 0.0007 0.0022 0.0042
Brugia malayi Immunoglobulin I-set domain containing protein 0.0016 0.0215 0.0544
Plasmodium falciparum conserved protein, unknown function 0.0013 0.0156 0.1312
Trichomonas vaginalis voltage and ligand gated potassium channel, putative 0.0008 0.0043 0.0092
Schistosoma mansoni cyclin B 0.0116 0.2392 0.3637
Brugia malayi Serotonin receptor 0.0073 0.1458 0.3733
Echinococcus multilocularis nuclear factor of activated T cells 5 0.0082 0.1651 0.223
Trypanosoma brucei DNA polymerase kappa, putative 0.0021 0.0334 0.1385
Loa Loa (eye worm) hypothetical protein 0.0007 0.0012 0.0014
Loa Loa (eye worm) hypothetical protein 0.0007 0.0022 0.0029
Echinococcus granulosus serine:threonine protein kinase PAK 3 0.0038 0.0694 0.0935
Mycobacterium ulcerans lipase LipD 0.0073 0.1453 1
Schistosoma mansoni lamin 0.0027 0.0454 0.0687
Echinococcus multilocularis ephrin type A receptor 4 A 0.007 0.1385 0.1871
Echinococcus granulosus cyclin G2 0.0014 0.0182 0.0243
Echinococcus multilocularis peptide (allatostatin:somatostatin) 0.0073 0.1458 0.197
Echinococcus granulosus FTZ F1 nuclear receptor protein 0.001 0.0082 0.0107
Echinococcus multilocularis p21 activated protein kinase 1 Dpak1 0.0038 0.0694 0.0935
Trypanosoma brucei DNA polymerase kappa, putative 0.0015 0.0189 0.0778
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0073 0.1458 0.2217
Echinococcus multilocularis g protein linked acetylcholine receptor gar 2a 0.0073 0.1458 0.197
Loa Loa (eye worm) TK/EPH protein kinase 0.0072 0.1429 0.2172
Trypanosoma cruzi DNA polymerase kappa, putative 0.0021 0.0334 0.1355
Trypanosoma cruzi cdc2-related kinase 1 0.0049 0.0932 0.3867
Trypanosoma cruzi Lanosterol 14-alpha demethylase 0.0008 0.0038 0.0111
Trichomonas vaginalis cyclin B3, putative 0.0014 0.0182 0.0676
Loa Loa (eye worm) hypothetical protein 0.0073 0.1453 0.2208
Schistosoma mansoni rab geranylgeranyl transferase alpha subunit 0.0021 0.0334 0.0505
Entamoeba histolytica cyclin family protein 0.006 0.1173 0.4859
Trypanosoma cruzi GTP-binding nuclear protein rtb2, putative 0.0021 0.0329 0.1332
Mycobacterium ulcerans acetyl-CoA synthetase 0.0007 0.0022 0.0069
Trypanosoma brucei importin beta-1 subunit, putative 0.0029 0.0494 0.2057
Echinococcus multilocularis serotonin receptor 0.0073 0.1458 0.197
Mycobacterium ulcerans cytochrome P450 51B1 Cyp51B1 0.0008 0.0038 0.0183
Plasmodium vivax acyl-CoA synthetase, putative 0.0018 0.0261 0.1731
Brugia malayi AMP-binding enzyme family protein 0.0007 0.0022 0.0049
Trypanosoma cruzi pyruvate kinase 2, putative 0.0037 0.0675 0.2787
Echinococcus multilocularis cyclin G2 0.0014 0.0182 0.0243
Echinococcus granulosus g protein coupled receptor 0.0073 0.1458 0.197
Leishmania major lanosterol 14-alpha-demethylase, putative 0.0008 0.0038 0.0148
Echinococcus granulosus beta LACTamase domain containing family member 0.0073 0.1453 0.1962
Echinococcus multilocularis rhodopsin orphan GPCR 0.0073 0.1458 0.197
Schistosoma mansoni hypothetical protein 0.0016 0.0206 0.031
Giardia lamblia DINP protein human, muc B family 0.0021 0.0334 0.1355
Trypanosoma cruzi p21-activated kinase 3, putative 0.0022 0.0354 0.1439
Schistosoma mansoni acetyl-CoA synthetase 0.0007 0.0022 0.0029
Leishmania major mitotic cyclin, putative 0.0014 0.0182 0.075
Trypanosoma brucei DNA damage repair protein, putative 0.0007 0.0012 0.0035
Onchocerca volvulus Netrin receptor homolog 0.0016 0.0215 0.0769
Schistosoma mansoni cyclin G 0.0014 0.0182 0.0273
Trypanosoma brucei unspecified product 0.0015 0.0189 0.0778
Trypanosoma brucei hypothetical protein, conserved 0.0007 0.0012 0.0035
Mycobacterium tuberculosis Conserved protein 0.0073 0.1453 0.1453
Trypanosoma cruzi DNA polymerase kappa, putative 0.0021 0.0334 0.1355
Loa Loa (eye worm) hypothetical protein 0.0073 0.1458 0.2217

Activities

Activity type Activity value Assay description Source Reference
Inhibition (functional) = 61 % Inhibitory activity of Ca-ionophore-A23187-induced Leukotriene B4 (LTB4) release in human polymorphonuclear leukocytes at the dose of 3 micro M concentration ChEMBL. 8151618
Inhibition (functional) = 61 % Inhibitory activity of Ca-ionophore-A23187-induced Leukotriene B4 (LTB4) release in human polymorphonuclear leukocytes at the dose of 3 micro M concentration ChEMBL. 8151618

Phenotypes

Whole-cell/tissue/organism interactions

We have no records of whole-cell/tissue assays done with this compound What does this mean?

Many chemical entities in TDR Targets come from high-throughput screenings with whole cells or tissue samples, and not all assayed compounds have been tested against a single a single target protein, probably because they get ruled out during screening process. Even if these compounds may have not been of interest in the original screening, they may come as interesting leads for other screening assays. Furthermore, we may be able to propose drug-target associations using chemical similarities and network patterns.

Annotated phenotypes:

We have no manually annotated phenotypes for this drug. What does this mean? / Care to help?
In TDR Targets, information about phenotypes that are caused by drugs, or by genetic manipulation of cells (e.g. gene knockouts or knockdowns) is manually curated from the literature. These descriptions help to describe the potential of the target for drug development. If no information is available for this gene or if the information is incomplete, this may mean that i) the papers containing this information either appeared after the curation effort for this organism was carried out or they were inadvertently missed by curators; or that ii) the curation effort for this organism has not yet started.
 
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External resources for this compound

Bibliographic References

1 literature reference was collected for this gene.

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