Detailed information for compound 331600

Basic information

Technical information
  • TDR Targets ID: 331600
  • Name: (2R)-1-(1-methylpyrrol-2-yl)-2-phenyl-2-piper idin-1-ylethanone
  • MW: 282.38 | Formula: C18H22N2O
  • H donors: 0 H acceptors: 1 LogP: 3.29 Rotable bonds: 4
    Rule of 5 violations (Lipinski): 1
  • SMILES: O=C(c1cccn1C)[C@@H](c1ccccc1)N1CCCCC1
  • InChi: 1S/C18H22N2O/c1-19-12-8-11-16(19)18(21)17(15-9-4-2-5-10-15)20-13-6-3-7-14-20/h2,4-5,8-12,17H,3,6-7,13-14H2,1H3/t17-/m1/s1
  • InChiKey: JBCUNENIAGFXMM-QGZVFWFLSA-N  


Substructure search Similarity search

Network

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Synonyms

  • (2R)-1-(1-methylpyrrol-2-yl)-2-phenyl-2-(1-piperidyl)ethanone
  • (2R)-1-(1-methyl-2-pyrrolyl)-2-phenyl-2-(1-piperidyl)ethanone
  • (2R)-1-(1-methylpyrrol-2-yl)-2-phenyl-2-piperidin-1-yl-ethanone
  • (2R)-1-(1-methylpyrrol-2-yl)-2-phenyl-2-piperidino-ethanone

Targets

Known targets for this compound

Species Target name Source Bibliographic reference
Rattus norvegicus Monoamine oxidase A Starlite/ChEMBL References

Predicted pathogen targets for this compound

By orthology
Species Potential target Known druggable target/s Ortholog Group
Mycobacterium ulcerans flavin-containing monoamine oxidase AofH Get druggable targets OG5_130722 All targets in OG5_130722
Mycobacterium tuberculosis Probable flavin-containing monoamine oxidase AofH (amine oxidase) (MAO) Get druggable targets OG5_130722 All targets in OG5_130722
Mycobacterium ulcerans flavin-containing monoamine oxidase AofH Get druggable targets OG5_130722 All targets in OG5_130722
By sequence similarity to non orthologous known druggable targets
Species Potential target Known druggable target Length Alignment span Identity
Brugia malayi amine oxidase, flavin-containing family protein Monoamine oxidase A   526 aa 464 aa 21.6 %
Dictyostelium discoideum amine oxidase Monoamine oxidase A   526 aa 491 aa 31.0 %
Dictyostelium discoideum hypothetical protein Monoamine oxidase A   526 aa 518 aa 22.4 %
Dictyostelium discoideum hypothetical protein Monoamine oxidase A   526 aa 524 aa 22.9 %
Obtained from network model

Ranking Plot

Putative Targets List

Species Potential target Raw Global Species
Plasmodium vivax ADP-dependent DNA helicase RecQ, putative 0.009 0.0225 0.0833
Schistosoma mansoni retinoic acid receptor RXR 0.0061 0.0133 0.0147
Loa Loa (eye worm) hypothetical protein 0.0087 0.0215 0.0745
Trypanosoma cruzi DNA repair protein RAD2, putative 0.0022 0.0007 0.0019
Plasmodium vivax hypothetical protein, conserved 0.006 0.0131 0.0479
Trichomonas vaginalis chromodomain helicase DNA binding protein, putative 0.007 0.016 0.0521
Schistosoma mansoni chromodomain helicase DNA binding protein 0.007 0.0161 0.0179
Entamoeba histolytica recQ family DNA helicase 0.0035 0.0051 0.0148
Echinococcus multilocularis dna polymerase eta 0.0188 0.0541 0.0598
Schistosoma mansoni serine/threonine protein kinase 0.0021 0.0004 0.0005
Loa Loa (eye worm) nucleolar RNA-associated protein alpha 0.0304 0.0913 0.3185
Trypanosoma brucei calpain-like cysteine peptidase, putative 0.0131 0.0356 0.1329
Brugia malayi hypothetical protein 0.0087 0.0215 0.0297
Echinococcus multilocularis dual specificity mitogen activated protein 0.0082 0.02 0.022
Echinococcus granulosus endonuclease exonuclease phosphatase 0.06 0.1861 0.2063
Entamoeba histolytica chromodomain-helicase-DNA-binding protein, putative 0.0057 0.0121 0.0355
Leishmania major phosphoglycerate kinase B, cytosolic 0.0171 0.0484 0.1796
Leishmania major DNA polymerase eta, putative 0.0095 0.0242 0.0889
Entamoeba histolytica exodeoxyribonuclease III, putative 0.0057 0.0121 0.0355
Loa Loa (eye worm) hypothetical protein 0.0192 0.0553 0.1926
Brugia malayi Bromodomain containing protein 0.024 0.0708 0.0979
Brugia malayi Nuclear hormone receptor family member nhr-19 0.0061 0.0133 0.0183
Loa Loa (eye worm) hypothetical protein 0.0052 0.0104 0.0354
Brugia malayi AMP-binding enzyme family protein 0.0049 0.0093 0.0128
Echinococcus multilocularis microtubule associated protein 2 0.283 0.9012 1
Trichomonas vaginalis phosphofructokinase, putative 0.0107 0.0279 0.0914
Onchocerca volvulus Alhambra homolog 0.006 0.0131 0.0128
Toxoplasma gondii BRCA1 C Terminus (BRCT) domain-containing protein 0.0049 0.0095 0.0352
Loa Loa (eye worm) hypothetical protein 0.0057 0.0121 0.0416
Entamoeba histolytica chromodomain-helicase-DNA-binding protein, putative 0.0057 0.0121 0.0355
Echinococcus multilocularis importin subunit beta 1 0.0028 0.0029 0.0029
Echinococcus multilocularis expressed protein 0.0033 0.0045 0.0047
Plasmodium vivax SET domain containing protein 0.0021 0.0005 0.0012
Trichomonas vaginalis PIKK family atypical protein kinase 0.0026 0.0021 0.0062
Echinococcus granulosus bloom syndrome protein 0.0138 0.038 0.0419
Schistosoma mansoni z-protein (S1r protein) 0.0028 0.0028 0.0031
Loa Loa (eye worm) heterochromatin protein 1 0.0293 0.0878 0.3064
Leishmania major flap endonuclease-1 (FEN-1), putative 0.0108 0.0282 0.104
Schistosoma mansoni mixed-lineage leukemia protein mll 0.0056 0.0118 0.0131
Trichomonas vaginalis rotamase, putative 0.0033 0.0045 0.014
Echinococcus multilocularis DNA (apurinic or apyrimidinic site) lyase 0.0057 0.0121 0.0132
Trypanosoma cruzi Phosphatidylinositol 3-kinase tor2 0.0044 0.0079 0.0286
Loa Loa (eye worm) tyrosyl-DNA phosphodiesterase 0.0065 0.0146 0.0501
Trichomonas vaginalis PIKK family atypical protein kinase 0.0033 0.0043 0.0133
Trichomonas vaginalis CMGC family protein kinase 0.0106 0.0279 0.0912
Brugia malayi Nuclear hormone receptor family member nhr-49 0.0061 0.0133 0.0183
Trypanosoma cruzi transcription elongation factor-like protein, putative 0.0029 0.0031 0.0106
Echinococcus multilocularis ATP dependent DNA helicase Q5 0.0069 0.016 0.0175
Trypanosoma brucei DNA polymerase kappa, putative 0.0164 0.0463 0.1727
Trichomonas vaginalis CAMK family protein kinase 0.0197 0.0568 0.1865
Toxoplasma gondii phosphoglycerate kinase PGKII 0.0171 0.0484 0.1807
Echinococcus granulosus NADP dependent isocitrate dehydrogenase 0.0031 0.0037 0.0039
Giardia lamblia hypothetical protein 0.0022 0.0007 0.0015
Echinococcus granulosus chromodomain helicase DNA binding protein 1 0.0057 0.0121 0.0132
Schistosoma mansoni phd finger protein 0.004 0.0066 0.0073
Loa Loa (eye worm) latrophilin receptor protein 2 0.0097 0.0249 0.0862
Brugia malayi RNA, U transporter 1 0.0081 0.0197 0.0272
Onchocerca volvulus Heterochromatin protein 1 homolog 0.0181 0.0519 0.0517
Trypanosoma cruzi DNA polymerase kappa, putative 0.0164 0.0463 0.1721
Loa Loa (eye worm) hypothetical protein 0.0049 0.0093 0.0319
Echinococcus granulosus COUP TF:Svp nuclear hormone receptor 0.0061 0.0133 0.0145
Echinococcus multilocularis insulin receptor 0.0047 0.0088 0.0095
Brugia malayi Bromodomain containing protein 0.0121 0.0326 0.045
Trichomonas vaginalis PIKK family atypical protein kinase 0.0024 0.0014 0.0037
Echinococcus multilocularis muscleblind protein 0.0911 0.286 0.3172
Echinococcus granulosus lamin dm0 0.0081 0.0198 0.0218
Echinococcus granulosus calpain 7 C02 family 0.0021 0.0004 0.0002
Loa Loa (eye worm) hypothetical protein 0.008 0.0194 0.0669
Loa Loa (eye worm) hypothetical protein 0.007 0.0161 0.0554
Trypanosoma brucei peptidyl-prolyl cis-trans isomerase/rotamase, putative 0.0033 0.0042 0.0156
Echinococcus granulosus DNA repair protein complementing XP G cells 0.0022 0.0007 0.0006
Schistosoma mansoni phosphoglycerate kinase 0.0171 0.0484 0.0537
Brugia malayi CHD4 protein 0.007 0.0161 0.0222
Trypanosoma cruzi phosphoglycerate kinase, putative 0.0063 0.0138 0.0507
Echinococcus multilocularis replication factor c subunit 1 0.002 0.0002 0.00000019443
Schistosoma mansoni chromobox protein 0.0057 0.0121 0.0135
Loa Loa (eye worm) hypothetical protein 0.0029 0.003 0.0095
Schistosoma mansoni tyrosine kinase 0.0078 0.0188 0.0208
Schistosoma mansoni phosphoglucomutase 0.0113 0.0298 0.0331
Mycobacterium ulcerans fructose-bisphosphate aldolase 0.0295 0.0883 0.5247
Entamoeba histolytica calpain large subunit domain III containing protein 0.0021 0.0004 0.0011
Echinococcus granulosus Chromobox protein 3 0.0057 0.0121 0.0132
Echinococcus granulosus insulin growth factor 1 receptor beta 0.0047 0.0088 0.0095
Loa Loa (eye worm) hypothetical protein 0.0097 0.0249 0.0862
Loa Loa (eye worm) 6-phosphofructokinase 0.0107 0.0279 0.0969
Giardia lamblia Kinase, CMGC MAPK 0.0106 0.0279 0.0808
Loa Loa (eye worm) hypothetical protein 0.0124 0.0335 0.1164
Schistosoma mansoni tar DNA-binding protein 0.0137 0.0376 0.0417
Brugia malayi PHD-finger family protein 0.0087 0.0215 0.0297
Echinococcus multilocularis GPCR, family 2 0.0097 0.0249 0.0274
Schistosoma mansoni tyrosine kinase 0.0047 0.0088 0.0097
Echinococcus granulosus Nuclear hormone receptor family member nhr 41 0.0061 0.0133 0.0145
Trypanosoma cruzi calpain-like cysteine peptidase, putative 0.0131 0.0356 0.1323
Brugia malayi calpain family protein 1 0.007 0.0161 0.0222
Brugia malayi polk-prov protein 0.0071 0.0164 0.0226
Plasmodium falciparum DNA repair protein RAD2, putative 0.0022 0.0007 0.0028
Loa Loa (eye worm) CXXC zinc finger family protein 0.0149 0.0415 0.1444
Schistosoma mansoni hypothetical protein 0.0147 0.041 0.0455
Schistosoma mansoni tar DNA-binding protein 0.0137 0.0376 0.0417
Schistosoma mansoni retinoid-x-receptor (RXR) 0.0061 0.0133 0.0147
Echinococcus granulosus ribonuclease H1 0.0113 0.0298 0.0328
Schistosoma mansoni kinase 0.0101 0.026 0.0288
Schistosoma mansoni nuclear receptor 0.0029 0.003 0.0033
Loa Loa (eye worm) hypothetical protein 0.0032 0.0041 0.0134
Mycobacterium tuberculosis Inositol-1-monophosphatase SuhB 0.0036 0.0052 0.0342
Entamoeba histolytica exonuclease, putative 0.0022 0.0007 0.0022
Trypanosoma brucei ISWI complex protein 0.0047 0.0088 0.0326
Leishmania major target of rapamycin (TOR) kinase 1, putative 0.0044 0.0079 0.028
Loa Loa (eye worm) hypothetical protein 0.0036 0.0054 0.0179
Trichomonas vaginalis conserved hypothetical protein 0.0057 0.0121 0.0393
Onchocerca volvulus Bile acid receptor homolog 0.0061 0.0133 0.013
Trichomonas vaginalis conserved hypothetical protein 0.0026 0.0022 0.0063
Schistosoma mansoni inositol monophosphatase 0.004 0.0066 0.0073
Brugia malayi nuclear hormone receptor 0.0061 0.0133 0.0183
Trichomonas vaginalis STE family protein kinase 0.0082 0.02 0.0653
Brugia malayi ATP-dependent DNA helicase, RecQ family protein 0.0069 0.016 0.022
Trypanosoma cruzi UDP-galactopyranose mutase 0.0025 0.0018 0.006
Giardia lamblia GTOR 0.0044 0.0079 0.0223
Loa Loa (eye worm) nuclear receptor nhr-7B 0.0029 0.003 0.0095
Onchocerca volvulus Rap guanine nucleotide exchange factor 1 homolog 0.0192 0.0553 0.0551
Loa Loa (eye worm) hypothetical protein 0.0057 0.0121 0.0416
Echinococcus multilocularis insulin growth factor 1 receptor beta 0.0047 0.0088 0.0095
Echinococcus multilocularis protoporphyrinogen oxidase 0.0025 0.0018 0.0018
Entamoeba histolytica hypothetical protein 0.002 0.0002 0.0007
Trichomonas vaginalis chromodomain-helicase-DNA-binding protein, putative 0.0084 0.0206 0.0671
Plasmodium falciparum conserved Plasmodium protein, unknown function 0.0084 0.0205 0.0767
Schistosoma mansoni serine/threonine protein kinase 0.0106 0.0279 0.0309
Echinococcus granulosus Jumonji AT rich interactive domain 1B 0.0032 0.004 0.0041
Echinococcus multilocularis nuclear receptor 2DBD gamma 0.0061 0.0133 0.0145
Mycobacterium ulcerans hypothetical protein 0.0042 0.0072 0.0415
Echinococcus granulosus hypothetical protein 0.0027 0.0023 0.0023
Echinococcus granulosus Ataxin 2 N terminaldomain containing protein 0.0023 0.0012 0.0011
Echinococcus granulosus histone lysine N methyltransferase H3 lysine 36 0.0039 0.0064 0.0068
Schistosoma mansoni 6-phosphofructokinase 0.0107 0.0279 0.031
Toxoplasma gondii histone lysine methyltransferase SET/SUV39 0.0127 0.0344 0.1283
Brugia malayi RNase H family protein 0.0113 0.0298 0.0412
Loa Loa (eye worm) helicase DNA-binding protein 0.0024 0.0014 0.004
Mycobacterium ulcerans acyl-CoA synthetase 0.0049 0.0093 0.054
Brugia malayi hypothetical protein 0.0052 0.0104 0.0143
Loa Loa (eye worm) hypothetical protein 0.0025 0.0018 0.0056
Echinococcus granulosus mitogen activated protein kinase 3 0.0106 0.0279 0.0307
Loa Loa (eye worm) pigment dispersing factor receptor c 0.0307 0.0922 0.3217
Trypanosoma brucei DNA polymerase IV, putative 0.0157 0.044 0.1642
Schistosoma mansoni hypothetical protein 0.021 0.061 0.0677
Echinococcus multilocularis family C2 unassigned peptidase (C02 family) 0.0073 0.0172 0.0189
Trypanosoma brucei mitochondrial DNA polymerase beta 0.0601 0.1865 0.6963
Schistosoma mansoni Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) 0.0278 0.083 0.0921
Trichomonas vaginalis ap endonuclease, putative 0.0057 0.0121 0.0393
Onchocerca volvulus 0.0124 0.0335 0.0333
Toxoplasma gondii LsmAD domain-containing protein 0.0052 0.0104 0.0385
Loa Loa (eye worm) hypothetical protein 0.0029 0.003 0.0095
Onchocerca volvulus Steroid hormone receptor family member cnr14 homolog 0.0061 0.0133 0.013
Echinococcus granulosus BRK domain containing protein 0.0024 0.0014 0.0013
Echinococcus multilocularis protein quaking 0.0027 0.0023 0.0023
Brugia malayi MH2 domain containing protein 0.0025 0.0019 0.0025
Brugia malayi AMP-binding enzyme family protein 0.0049 0.0093 0.0128
Schistosoma mansoni hypothetical protein 0.0097 0.0249 0.0276
Schistosoma mansoni topbp1 0.002 0.0002 0.0003
Plasmodium falciparum chromodomain-helicase-DNA-binding protein 1 homolog, putative 0.0057 0.0121 0.0453
Trypanosoma cruzi transcription elongation factor s-II, putative 0.0029 0.0031 0.0106
Echinococcus granulosus flap endonuclease GEN 1 0.0022 0.0007 0.0006
Entamoeba histolytica serine/threonine protein kinase, putative 0.0197 0.0568 0.1658
Trypanosoma cruzi polo-like protein kinase, putative 0.0197 0.0568 0.2113
Echinococcus multilocularis peregrin 0.01 0.0259 0.0285
Echinococcus multilocularis bromodomain adjacent to zinc finger domain 0.0193 0.0558 0.0616
Onchocerca volvulus 0.0025 0.0018 0.0016
Loa Loa (eye worm) AGC/GRK/GRK protein kinase 0.0021 0.0004 0.0007
Loa Loa (eye worm) hypothetical protein 0.0188 0.0541 0.1884
Onchocerca volvulus 0.0049 0.0093 0.0091
Trichomonas vaginalis PIKK family atypical protein kinase 0.0035 0.005 0.0157
Brugia malayi Associated with TFs and helicases family protein 0.0081 0.0198 0.0273
Schistosoma mansoni multiple ankyrin repeats single kh domain protein 0.0088 0.022 0.0244
Brugia malayi 6-phosphofructokinase 0.0107 0.0279 0.0386
Trichomonas vaginalis conserved hypothetical protein 0.0112 0.0296 0.0971
Echinococcus multilocularis mixed lineage leukemia protein mll 0.0037 0.0055 0.0058
Echinococcus multilocularis 6 phosphofructokinase 0.0107 0.0279 0.0307
Treponema pallidum phosphoglycerate kinase 0.0171 0.0484 0.2574
Brugia malayi Furin-like cysteine rich region family protein 0.0147 0.0408 0.0564
Loa Loa (eye worm) hypothetical protein 0.0057 0.0121 0.0416
Trichomonas vaginalis myo inositol monophosphatase, putative 0.004 0.0066 0.0209
Entamoeba histolytica myo-inositol monophosphatase, putative 0.004 0.0066 0.0192
Trypanosoma brucei DNA polymerase kappa, putative 0.0164 0.0463 0.1727
Brugia malayi Pre-SET motif family protein 0.0849 0.2659 0.3678
Brugia malayi Smad1 0.0025 0.0019 0.0025
Brugia malayi Probable G protein-coupled receptor kinase F19C6.1, putative 0.0021 0.0004 0.0005
Toxoplasma gondii hypothetical protein 0.0029 0.0031 0.0113
Loa Loa (eye worm) hypothetical protein 0.007 0.0161 0.0555
Loa Loa (eye worm) hypothetical protein 0.0061 0.0133 0.0456
Trypanosoma brucei ATP-dependent DEAD/H DNA helicase recQ, putative 0.0084 0.0205 0.0764
Trichomonas vaginalis CAMK family protein kinase 0.0197 0.0568 0.1865
Trichomonas vaginalis phosphofructokinase, putative 0.0029 0.003 0.009
Toxoplasma gondii XPG N-terminal domain-containing protein 0.0022 0.0007 0.0026
Echinococcus multilocularis retinoic acid receptor rxr beta a retinoic acid receptor rxr alpha a retinoic acid receptor rxr alpha 0.0029 0.003 0.003
Brugia malayi Nuclear hormone receptor family member nhr-3 0.0061 0.0133 0.0183
Echinococcus multilocularis chromodomain helicase DNA binding protein 7 0.0024 0.0014 0.0013
Giardia lamblia PHD finger protein 15 0.006 0.0131 0.0375
Giardia lamblia Kinase, PLK 0.0197 0.0568 0.1653
Loa Loa (eye worm) mbt repeat family protein 0.0149 0.0416 0.1448
Giardia lamblia Flap structure-specific endonuclease 0.0108 0.0282 0.0818
Schistosoma mansoni jumonji domain containing protein 0.0157 0.044 0.0488
Mycobacterium ulcerans oxidoreductase 0.0025 0.0018 0.0095
Brugia malayi Nuclear hormone receptor family member nhr-41 0.0061 0.0133 0.0183
Trichomonas vaginalis PIKK family atypical protein kinase 0.0024 0.0014 0.0037
Echinococcus granulosus FKBP12 rapamycin complex associated protein 0.0044 0.0079 0.0085
Loa Loa (eye worm) nuclear Hormone Receptor family member 0.0061 0.0133 0.0456
Schistosoma mansoni tsg101-related 0.0047 0.0089 0.0099
Brugia malayi hypothetical protein 0.002 0.0002 0.0003
Wolbachia endosymbiont of Brugia malayi fructose-1,6-bisphosphatase 0.004 0.0066 0.1312
Echinococcus multilocularis histone lysine N methyltransferase MLL3 0.0044 0.0077 0.0083
Loa Loa (eye worm) PWWP domain-containing protein 0.0029 0.0031 0.0099
Trypanosoma brucei DNA polymerase IV, putative 0.0164 0.0463 0.1727
Schistosoma mansoni microtubule-associated protein tau 0.283 0.9012 1
Loa Loa (eye worm) hypothetical protein 0.0129 0.035 0.1216
Schistosoma mansoni family C2 unassigned peptidase (C02 family) 0.007 0.0161 0.0179
Echinococcus multilocularis cadherin EGF LAG seven pass G type receptor 0.0097 0.0249 0.0274
Brugia malayi Muscleblind-like protein 0.0911 0.286 0.3956
Giardia lamblia Fructose-bisphosphate aldolase 0.0604 0.1874 0.5473
Echinococcus multilocularis chromobox protein 1 0.0293 0.0878 0.0972
Trichomonas vaginalis PIKK family atypical protein kinase 0.0035 0.005 0.0157
Leishmania major 4-coumarate:coa ligase-like protein 0.0049 0.0093 0.0333
Onchocerca volvulus 0.0149 0.0415 0.0413
Trypanosoma cruzi ATP-dependent DEAD/H DNA helicase recQ, putative 0.0035 0.0051 0.0181
Loa Loa (eye worm) nuclear hormone receptor family member nhr-31 0.0061 0.0133 0.0456
Treponema pallidum diphosphate--fructose-6-phosphate 1-phosphotransferase 0.0107 0.0279 0.148
Loa Loa (eye worm) hypothetical protein 0.0169 0.048 0.1673
Loa Loa (eye worm) nuclear hormone receptor family member nhr-14 0.0061 0.0133 0.0456
Trypanosoma cruzi polo-like protein kinase, putative 0.0197 0.0568 0.2113
Brugia malayi latrophilin 2 splice variant baaae 0.021 0.061 0.0844
Loa Loa (eye worm) AGC/GRK/BARK protein kinase 0.0021 0.0004 0.0007
Chlamydia trachomatis acylglycerophosphoethanolamine acyltransferase 0.0036 0.0054 0.1064
Trypanosoma brucei DNA polymerase kappa, putative 0.0164 0.0463 0.1727
Echinococcus multilocularis snurportin 1 0.0304 0.0913 0.101
Echinococcus granulosus dna polymerase eta 0.0188 0.0541 0.0598
Brugia malayi nuclear hormone receptor family member nhr-6 0.0029 0.003 0.004
Brugia malayi MH2 domain containing protein 0.0373 0.1134 0.1568
Brugia malayi Heterochromatin protein 1 0.0293 0.0878 0.1214
Schistosoma mansoni hypothetical protein 0.0334 0.1008 0.1118
Echinococcus granulosus hepatocyte nuclear factor 4 alpha 0.0061 0.0133 0.0145
Trypanosoma cruzi mitochondrial DNA polymerase beta, putative 0.0601 0.1865 0.6961
Mycobacterium ulcerans fatty-acid-CoA ligase 0.0049 0.0093 0.054
Echinococcus multilocularis polycomb protein SCMH1 0.0149 0.0416 0.0459
Echinococcus multilocularis ecdysone induced protein 78C 0.0061 0.0133 0.0145
Echinococcus granulosus TGF beta signal transducer SmadC 0.0025 0.0019 0.0018
Schistosoma mansoni ecdysone-induced protein 78c (dr-78) 0.0032 0.0041 0.0045
Schistosoma mansoni chromobox protein 0.0057 0.0121 0.0135
Echinococcus granulosus intermediate filament protein 0.0081 0.0198 0.0218
Echinococcus granulosus 5'partial|histone lysine N methyltransferase SETDB2 0.0116 0.0311 0.0342
Schistosoma mansoni tyrosine kinase 0.0147 0.0408 0.0453
Brugia malayi M-phase phosphoprotein, mpp8 0.0146 0.0404 0.0558
Schistosoma mansoni hypothetical protein 0.0036 0.0054 0.006
Echinococcus multilocularis BRK domain containing protein 0.0024 0.0014 0.0013
Trypanosoma brucei ingi protein (ORF1) 0.0122 0.0329 0.1226
Onchocerca volvulus 0.0142 0.0394 0.0392
Echinococcus multilocularis expressed protein 0.0366 0.1112 0.1231
Leishmania major DNA polymerase kappa, putative 0.0042 0.0072 0.0255
Trichomonas vaginalis conserved hypothetical protein 0.0026 0.0022 0.0063
Plasmodium vivax flap endonuclease 1, putative 0.0108 0.0282 0.1046
Trichomonas vaginalis conserved hypothetical protein 0.0057 0.0121 0.0393
Loa Loa (eye worm) BRM protein 0.0078 0.0189 0.0653
Leishmania major PAS-domain containing phosphoglycerate kinase, putative 0.0063 0.0138 0.0502
Loa Loa (eye worm) pre-SET domain-containing protein family protein 0.0849 0.2659 0.9296
Onchocerca volvulus 0.0081 0.0198 0.0196
Schistosoma mansoni SET domain protein 0.0107 0.0281 0.0312
Trypanosoma cruzi tyrosyl-DNA Phosphodiesterase (Tdp1), putative 0.0065 0.0146 0.0536
Schistosoma mansoni tyrosine kinase 0.0078 0.0188 0.0208
Toxoplasma gondii CMGC kinase, MAPK family (ERK) MAPK-1 0.0106 0.0279 0.1039
Brugia malayi ATP-dependent DNA helicase, RecQ family protein 0.0069 0.016 0.022
Trypanosoma cruzi ribonuclease H1, putative 0.0113 0.0298 0.1106
Echinococcus granulosus global transcription activator snf2l2 0.0145 0.0402 0.0444
Trichomonas vaginalis flap endonuclease-1, putative 0.0022 0.0007 0.0017
Echinococcus multilocularis tumor protein p63 0.0332 0.1003 0.1111
Trypanosoma cruzi mitochondrial DNA polymerase beta-PAK, putative 0.0085 0.0208 0.077
Loa Loa (eye worm) MH2 domain-containing protein 0.0373 0.1134 0.396
Loa Loa (eye worm) hypothetical protein 0.0029 0.003 0.0095
Loa Loa (eye worm) hypothetical protein 0.0029 0.003 0.0095
Brugia malayi orphan nuclear receptor NR2E1 0.0029 0.003 0.004
Onchocerca volvulus 0.0061 0.0133 0.013
Brugia malayi Ligand-binding domain of nuclear hormone receptor family protein 0.0061 0.0133 0.0183
Echinococcus multilocularis atpase aaa+ type core atpase aaa type core 0.1594 0.5047 0.5599
Brugia malayi phosphofructokinase 0.0107 0.0279 0.0386
Brugia malayi F/Y-rich N-terminus family protein 0.0069 0.0158 0.0218
Brugia malayi ImpB/MucB/SamB family protein 0.0188 0.0541 0.0748
Loa Loa (eye worm) hypothetical protein 0.0036 0.0054 0.0179
Echinococcus multilocularis histone lysine N methyltransferase SETMAR 0.0127 0.0344 0.0379
Trypanosoma brucei DNA polymerase kappa, putative 0.0164 0.0463 0.1727
Brugia malayi Importin beta-1 subunit 0.0028 0.0029 0.0039
Trypanosoma brucei DNA polymerase kappa, putative 0.0164 0.0463 0.1727
Leishmania major target of rapamycin (TOR) kinase 2, putative 0.0044 0.0079 0.028
Loa Loa (eye worm) Smad1 0.0025 0.0019 0.0058
Trypanosoma cruzi calpain-like cysteine peptidase, putative 0.0131 0.0356 0.1323
Brugia malayi Nuclear hormone receptor family member nhr-1 0.0061 0.0133 0.0183
Trypanosoma brucei PAB1-binding protein , putative 0.0052 0.0104 0.0385
Trichomonas vaginalis fructose-bisphosphate aldolase, putative 0.0604 0.1874 0.6178
Plasmodium falciparum AP endonuclease (DNA-[apurinic or apyrimidinic site] lyase), putative 0.0057 0.0121 0.0454
Echinococcus multilocularis Ataxin 2, N terminal,domain containing protein 0.0023 0.0012 0.0011
Trichomonas vaginalis chromodomain helicase DNA binding protein, putative 0.0084 0.0206 0.0671
Trichomonas vaginalis DNA polymerase IV / kappa, putative 0.0164 0.0463 0.152
Plasmodium vivax ataxin-2 like protein, putative 0.0052 0.0104 0.0378
Mycobacterium leprae PROBABLE PROTOPORPHYRINOGEN OXIDASE HEMY (PROTOPORPHYRINOGEN-IX OXIDASE) (PROTOPORPHYRINOGENASE) (PPO) 0.0025 0.0018 0.0181
Echinococcus multilocularis diuretic hormone 44 receptor GPRdih2 0.0097 0.0249 0.0274
Brugia malayi cytoplasmic intermediate filament protein 0.0044 0.0077 0.0106
Trypanosoma brucei unspecified product 0.0093 0.0237 0.0882
Brugia malayi Disco-interacting protein 2 homolog 0.0038 0.0059 0.0081
Schistosoma mansoni Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) 0.0278 0.083 0.0921
Schistosoma mansoni calpain-7 (C02 family) 0.0021 0.0004 0.0004
Schistosoma mansoni helicase 0.0145 0.0402 0.0446
Loa Loa (eye worm) hypothetical protein 0.0025 0.0018 0.0056
Loa Loa (eye worm) hypothetical protein 0.0029 0.003 0.0095
Loa Loa (eye worm) intermediate filament protein 0.0081 0.0198 0.0686
Plasmodium vivax hypothetical protein, conserved 0.0027 0.0023 0.0078
Brugia malayi N-terminal motif family protein 0.0192 0.0553 0.0764
Schistosoma mansoni smad1 5 8 and 0.0025 0.0019 0.0021
Trypanosoma brucei Vps23 core domain containing protein, putative 0.0022 0.0009 0.0031
Mycobacterium ulcerans long-chain-fatty-acid--CoA ligase 0.0049 0.0093 0.054
Echinococcus granulosus dna polymerase kappa 0.0164 0.0463 0.0511
Trichomonas vaginalis PIKK family atypical protein kinase 0.0033 0.0043 0.0133
Schistosoma mansoni histone-lysine n-methyltransferase setb1 0.0179 0.0512 0.0568
Trichomonas vaginalis conserved hypothetical protein 0.0112 0.0296 0.0971
Schistosoma mansoni ataxia telangiectasia mutated (atm)-related 0.0044 0.0079 0.0087
Plasmodium falciparum isocitrate dehydrogenase [NADP], mitochondrial 0.0031 0.0037 0.0139
Loa Loa (eye worm) MH2 domain-containing protein 0.0025 0.0019 0.0058
Trichomonas vaginalis ribonuclease H1, putative 0.0113 0.0298 0.0976
Trichomonas vaginalis chromodomain helicase DNA binding protein, putative 0.0084 0.0206 0.0671
Leishmania major DNA polymerase kappa, putative,DNA polymerase IV, putative 0.0142 0.0394 0.1459
Loa Loa (eye worm) hypothetical protein 0.0149 0.0416 0.1448
Brugia malayi bZIP transcription factor family protein 0.0181 0.0519 0.0717
Leishmania major myo-inositol-1(or 4)-monophosphatase 1, putative 0.004 0.0066 0.0231
Schistosoma mansoni serine/threonine protein kinase 0.0021 0.0004 0.0005
Brugia malayi hypothetical protein 0.0029 0.003 0.004
Echinococcus granulosus Chromo domain 0.0081 0.0198 0.0217
Trypanosoma cruzi myo-inositol-1(or 4)-monophosphatase 1, putative 0.004 0.0066 0.0236
Trypanosoma brucei DNA polymerase kappa, putative 0.01 0.0259 0.0967
Trypanosoma cruzi mitogen-activated protein kinase 11, putative 0.0106 0.0279 0.1033
Trichomonas vaginalis chromodomain-helicase-DNA-binding protein, putative 0.0057 0.0121 0.0393
Schistosoma mansoni sex comb on midleg homolog 0.0149 0.0416 0.0462
Trichomonas vaginalis chromodomain-helicase-DNA-binding protein, putative 0.0057 0.0121 0.0393
Leishmania major DNA polymerase eta, putative 0.0188 0.0541 0.2008
Trichomonas vaginalis STE family protein kinase 0.0082 0.02 0.0653
Echinococcus granulosus calpain 0.0021 0.0004 0.0002
Echinococcus granulosus epidermal growth factor receptor 0.0147 0.0408 0.045
Trichomonas vaginalis fructose-bisphosphate aldolase, putative 0.0604 0.1874 0.6178
Echinococcus granulosus melanoma receptor tyrosine protein kinase 0.0079 0.019 0.0208
Echinococcus granulosus cadherin EGF LAG seven pass G type receptor 0.0097 0.0249 0.0274
Echinococcus granulosus exonuclease 1 0.0022 0.0007 0.0006
Leishmania major importin beta-1 subunit, putative 0.0023 0.0011 0.0028
Echinococcus multilocularis Smad4 0.0025 0.0019 0.0018
Trypanosoma brucei DNA polymerase kappa, putative 0.01 0.0259 0.0967
Trypanosoma brucei DNA polymerase beta thumb, putative 0.0085 0.0208 0.0776
Brugia malayi Pin1-type peptidyl-prolyl cis-trans isomerase, BmPin1 0.0033 0.0045 0.0061
Schistosoma mansoni TGF-beta signal transducer Smad2 0.0025 0.0019 0.0021
Echinococcus granulosus serine:threonine protein kinase PLK1 0.0197 0.0568 0.0627
Echinococcus granulosus polycomb protein SCMH1 0.0149 0.0416 0.0459
Loa Loa (eye worm) RNA recognition domain-containing protein domain-containing protein 0.0137 0.0376 0.1306
Entamoeba histolytica acyl-coA synthetase, putative 0.0049 0.0093 0.0272
Trichomonas vaginalis PIKK family atypical protein kinase 0.0029 0.0029 0.0088
Trypanosoma brucei phosphatidylinositol 3-kinase tor, putative 0.0021 0.0004 0.0014
Echinococcus granulosus Nuclear hormone receptor HR96 0.0029 0.003 0.003
Loa Loa (eye worm) RNA binding protein 0.0137 0.0376 0.1306
Entamoeba histolytica hypothetical protein 0.0057 0.0121 0.0355
Echinococcus granulosus muscleblind protein 0.0911 0.286 0.3172
Toxoplasma gondii histone lysine methyltransferase SET1 0.0238 0.0701 0.2618
Brugia malayi chromobox protein homolog 3 0.0169 0.048 0.0664
Loa Loa (eye worm) hypothetical protein 0.0038 0.0059 0.02
Echinococcus multilocularis BRK domain containing protein 0.0024 0.0014 0.0013
Trypanosoma cruzi telomerase reverse transcriptase, putative 0.0855 0.2677 1
Trichomonas vaginalis CMGC family protein kinase 0.0106 0.0279 0.0912
Echinococcus granulosus beta-adrenergic receptor kinase 0.0021 0.0004 0.0002
Plasmodium falciparum ATP-dependent 6-phosphofructokinase 0.0029 0.003 0.0111
Loa Loa (eye worm) hypothetical protein 0.0307 0.0922 0.3217
Entamoeba histolytica fructose-1,6-bisphosphate aldolase, putative 0.0604 0.1874 0.5477
Trichomonas vaginalis conserved hypothetical protein 0.0057 0.0121 0.0393
Trypanosoma cruzi ISWI complex protein 0.0047 0.0088 0.032
Mycobacterium ulcerans flavin-containing monoamine oxidase AofH 0.0359 0.1087 0.646
Loa Loa (eye worm) hypothetical protein 0.006 0.0131 0.0449
Echinococcus multilocularis DNA repair protein complementing XP G cells 0.0022 0.0007 0.0006
Brugia malayi amine oxidase, flavin-containing family protein 0.0025 0.0018 0.0025
Trichomonas vaginalis chromobox protein, putative 0.0057 0.0121 0.0393
Trypanosoma cruzi mitochondrial DNA polymerase beta-PAK, putative 0.0103 0.0268 0.0992
Plasmodium falciparum ataxin-2 like protein, putative 0.0052 0.0104 0.0387
Leishmania major ATP-dependent phosphofructokinase 0.0107 0.0279 0.103
Echinococcus multilocularis tyrosyl DNA phosphodiesterase 1 0.0065 0.0146 0.0159
Schistosoma mansoni DNA helicase recq5 0.0069 0.016 0.0177
Trichomonas vaginalis chromosome transmission fidelity factor, putative 0.002 0.0002 0.00000057814
Loa Loa (eye worm) bromodomain containing protein 0.0058 0.0123 0.0422
Entamoeba histolytica Activator 1 140 kDa subunit, putative 0.002 0.0002 0.0007
Leishmania major 4-coumarate:coa ligase-like protein 0.0049 0.0093 0.0333
Trypanosoma brucei phosphoglycerate kinase, putative 0.0063 0.0138 0.0514
Loa Loa (eye worm) glutaminase 0.0544 0.1682 0.5877
Trypanosoma brucei calpain-like protein, putative 0.0021 0.0004 0.0013
Brugia malayi mbt repeat family protein 0.0149 0.0416 0.0575
Giardia lamblia Exonuclease 1 0.0022 0.0007 0.0015
Trypanosoma cruzi DNA polymerase eta, putative 0.0095 0.0242 0.0895
Brugia malayi SET domain containing protein 0.0068 0.0154 0.0213
Echinococcus multilocularis inositol monophosphatase 1 0.004 0.0066 0.007
Onchocerca volvulus Nuclear receptor subfamily 6 group A member 1 homolog 0.0029 0.003 0.0027
Brugia malayi Latrophilin receptor protein 2 0.0097 0.0249 0.0344
Echinococcus multilocularis nuclear receptor nhr 48 0.0029 0.003 0.003
Loa Loa (eye worm) hypothetical protein 0.0049 0.0094 0.0322
Trichomonas vaginalis chromobox protein, putative 0.0057 0.0121 0.0393
Schistosoma mansoni amine oxidase 0.0025 0.0018 0.002
Trypanosoma cruzi DNA polymerase eta, putative 0.0188 0.0541 0.2013
Schistosoma mansoni inositol monophosphatase 0.004 0.0066 0.0073
Mycobacterium tuberculosis Probable fatty-acid-CoA ligase FadD2 (fatty-acid-CoA synthetase) (fatty-acid-CoA synthase) 0.0049 0.0093 0.0756
Schistosoma mansoni blooms syndrome DNA helicase 0.0035 0.0051 0.0056
Brugia malayi topoisomerase 0.002 0.0002 0.0003
Trichomonas vaginalis PIKK family atypical protein kinase 0.0033 0.0043 0.0133
Schistosoma mansoni hypothetical protein 0.0097 0.0249 0.0276
Echinococcus multilocularis COUP TF:Svp nuclear hormone receptor 0.0061 0.0133 0.0145
Giardia lamblia Telomerase catalytic subunit 0.0855 0.2677 0.7823
Plasmodium falciparum DNA repair protein REV1, putative 0.0042 0.0072 0.0269
Trichomonas vaginalis chromosome transmission fidelity factor, putative 0.002 0.0002 0.00000057814
Schistosoma mansoni bromodomain containing protein 0.0023 0.0012 0.0014
Trichomonas vaginalis PIKK family atypical protein kinase 0.0033 0.0043 0.0133
Trypanosoma cruzi ATP-dependent 6-phosphofructokinase, glycosomal 0.0107 0.0279 0.1035
Mycobacterium ulcerans DNA polymerase IV 0.0164 0.0463 0.2742
Trypanosoma cruzi cysteine peptidase, Clan CA, family C2, putative 0.0021 0.0004 0.0006
Brugia malayi Dual specificity mitogen-activated protein kinase kinase mek-2 0.0082 0.02 0.0276
Loa Loa (eye worm) hypothetical protein 0.0032 0.0041 0.0134
Echinococcus granulosus phosphoglycerate kinase 1 0.0171 0.0484 0.0535
Schistosoma mansoni smad 0.0025 0.0019 0.0021
Echinococcus granulosus disco interacting protein 2 0.004 0.0066 0.007
Trypanosoma cruzi DNA polymerase beta thumb, putative 0.0085 0.0208 0.077
Leishmania major 4-coumarate:coa ligase-like protein 0.0049 0.0093 0.0333
Trichomonas vaginalis conserved hypothetical protein 0.0033 0.0045 0.014
Schistosoma mansoni hypothetical protein 0.0334 0.1008 0.1118
Echinococcus granulosus 6 phosphofructokinase 0.0107 0.0279 0.0307
Entamoeba histolytica phosphofructokinase, putative 0.0107 0.0279 0.0816
Giardia lamblia Phosphoglycerate kinase 0.0171 0.0484 0.1409
Trypanosoma brucei calpain-like cysteine peptidase, putative 0.011 0.029 0.108
Echinococcus multilocularis chromobox protein 1 0.0293 0.0878 0.0972
Loa Loa (eye worm) ImpB/MucB/SamB family protein 0.0135 0.0371 0.1291
Leishmania major mitochondrial DNA polymerase beta 0.0601 0.1865 0.6959
Echinococcus granulosus Transcription factor JmjC domain containing protein 0.0197 0.057 0.063
Trypanosoma brucei BRCA1 C Terminus (BRCT) domain containing protein, putative 0.002 0.0002 0.0007
Entamoeba histolytica phosphoglycerate kinase, putative 0.0171 0.0484 0.1415
Trichomonas vaginalis chromodomain helicase DNA binding protein, putative 0.0084 0.0206 0.0671
Trypanosoma cruzi calpain cysteine peptidase, putative 0.0131 0.0356 0.1323
Loa Loa (eye worm) hypothetical protein 0.0038 0.0059 0.0197
Echinococcus multilocularis flap endonuclease 1 0.0108 0.0282 0.031
Echinococcus granulosus chromobox protein 1 0.0293 0.0878 0.0972
Schistosoma mansoni sex comb on midleg homolog 0.0149 0.0416 0.0462
Echinococcus multilocularis jumonji domain containing protein 0.0084 0.0206 0.0226
Loa Loa (eye worm) hypothetical protein 0.0036 0.0054 0.0179
Trypanosoma cruzi myo-inositol-1(or 4)-monophosphatase 1, putative 0.004 0.0066 0.0236
Trichomonas vaginalis conserved hypothetical protein 0.0057 0.0121 0.0393
Trypanosoma cruzi kinesin, putative 0.0021 0.0004 0.0006
Echinococcus granulosus tumor susceptibility gene 101 protein 0.007 0.0161 0.0176
Trypanosoma brucei variant surface glycoprotein (VSG), putative 0.011 0.029 0.108
Schistosoma mansoni nuclear hormone receptor 0.0061 0.0133 0.0147
Brugia malayi PHD-finger family protein 0.006 0.0131 0.018
Onchocerca volvulus Nuclear receptor subfamily 6 group A member 1 homolog 0.0029 0.003 0.0027
Schistosoma mansoni hypothetical protein 0.0029 0.0031 0.0034
Echinococcus granulosus lysine specific histone demethylase 1A 0.0025 0.0018 0.0018
Mycobacterium ulcerans long-chain fatty-acid CoA ligase 0.0049 0.0093 0.054
Entamoeba histolytica Rad52/22 family double-strand break repair protein, putative 0.0309 0.0929 0.2714
Schistosoma mansoni xp-G/rad2 DNA repair endonuclease family member 0.0022 0.0007 0.0008
Schistosoma mansoni lozenge 0.0059 0.0127 0.0141
Echinococcus multilocularis Chromo domain 0.0081 0.0198 0.0217
Mycobacterium leprae PROBABLE 6-PHOSPHOFRUCTOKINASE PFKA (PHOSPHOHEXOKINASE) (PHOSPHOFRUCTOKINASE) 0.0107 0.0279 0.3143
Mycobacterium leprae Probable phosphoglycerate kinase Pgk 0.0171 0.0484 0.5469
Toxoplasma gondii ImpB/MucB/SamB family protein 0.0042 0.0072 0.0267
Trypanosoma brucei ATP-dependent 6-phosphofructokinase, glycosomal 0.0107 0.0279 0.1042
Echinococcus multilocularis ribonuclease H1 0.0113 0.0298 0.0328
Echinococcus multilocularis Nuclear hormone receptor family member nhr 41 0.0061 0.0133 0.0145
Loa Loa (eye worm) flap endonuclease-1 0.0108 0.0282 0.0979
Brugia malayi Bloom's syndrome protein homolog 0.0138 0.038 0.0524
Brugia malayi Flap endonuclease-1 0.0108 0.0282 0.039
Schistosoma mansoni thyroid hormone receptor 0.0061 0.0133 0.0147
Schistosoma mansoni hypothetical protein 0.002 0.0001 0.0001
Brugia malayi nuclear receptor subfamily 1, group D, member 1, putative 0.0029 0.003 0.004
Loa Loa (eye worm) hypothetical protein 0.0049 0.0093 0.0317
Toxoplasma gondii ATP-dependent DNA helicase, RecQ family protein 0.0035 0.0051 0.0187
Plasmodium falciparum ATP-dependent 6-phosphofructokinase 0.0029 0.003 0.0111
Trypanosoma brucei calpain-like cysteine peptidase, putative 0.011 0.029 0.108
Trypanosoma brucei isocitrate dehydrogenase [NADP], mitochondrial precursor, putative 0.0031 0.0037 0.0137
Loa Loa (eye worm) hypothetical protein 0.0179 0.0512 0.1782
Schistosoma mansoni topbp1 0.002 0.0002 0.0003
Schistosoma mansoni xp-G/rad2 DNA repair endonuclease family 0.0022 0.0007 0.0008
Schistosoma mansoni nuclear receptor nhr-48 0.0029 0.003 0.0033
Schistosoma mansoni hypothetical protein 0.0919 0.2885 0.3201
Toxoplasma gondii 'chromo' (CHRromatin Organization MOdifier) domain-containing protein 0.0057 0.0121 0.0451
Mycobacterium ulcerans hypothetical protein 0.0317 0.0952 0.5658
Trichomonas vaginalis PIKK family atypical protein kinase 0.0026 0.0022 0.0064
Brugia malayi Valyl-tRNA synthetase 0.0057 0.0121 0.0167
Echinococcus multilocularis guanine nucleotide binding protein G(s) subunit 0.0278 0.083 0.0918
Trichomonas vaginalis conserved hypothetical protein 0.0057 0.0121 0.0393
Toxoplasma gondii histone lysine-specific demethylase LSD1/BHC110/KDMA1A 0.0032 0.0041 0.0151
Mycobacterium ulcerans monoamine oxidase 0.0025 0.0018 0.0095
Plasmodium falciparum DEAD/DEAH box helicase, putative 0.0021 0.0006 0.0023
Mycobacterium tuberculosis Fatty-acid-AMP ligase FadD30 (fatty-acid-AMP synthetase) (fatty-acid-AMP synthase) 0.0036 0.0054 0.0357
Schistosoma mansoni nuclear hormone receptor 0.0029 0.003 0.0033
Loa Loa (eye worm) hypothetical protein 0.0036 0.0054 0.0179
Loa Loa (eye worm) tumor suppressor 0.0316 0.095 0.3316
Echinococcus multilocularis neuropeptide s receptor 0.0493 0.1518 0.1682
Onchocerca volvulus 0.0023 0.0011 0.0008
Schistosoma mansoni tar DNA-binding protein 0.0137 0.0376 0.0417
Entamoeba histolytica protein kinase, putative 0.0023 0.0011 0.0031
Echinococcus multilocularis phosphoglycerate kinase 1 0.0171 0.0484 0.0535
Loa Loa (eye worm) DR-78 0.0029 0.003 0.0095
Entamoeba histolytica phosphofructokinase, putative 0.0107 0.0279 0.0816
Trichomonas vaginalis PIKK family atypical protein kinase 0.0044 0.0079 0.0252
Brugia malayi Inositol-1 0.004 0.0066 0.009
Toxoplasma gondii histone lysine-specific demethylase 0.0025 0.0018 0.0067
Brugia malayi hypothetical protein 0.0032 0.0041 0.0055
Toxoplasma gondii ATP-dependent DNA helicase, RecQ family protein 0.0069 0.016 0.0594
Toxoplasma gondii isocitrate dehydrogenase 0.0031 0.0037 0.0137
Schistosoma mansoni jumonji/arid domain-containing protein 0.0085 0.0211 0.0234
Mycobacterium ulcerans protoporphyrinogen oxidase 0.0025 0.0018 0.0095
Trichomonas vaginalis CAMK family protein kinase 0.0197 0.0568 0.1865
Trichomonas vaginalis flap endonuclease-1, putative 0.0022 0.0007 0.0017
Echinococcus granulosus histone lysine N methyltransferase NSD3 0.0107 0.0281 0.031
Echinococcus multilocularis BRK domain containing protein 0.0024 0.0014 0.0013
Brugia malayi PWWP domain containing protein 0.0029 0.0031 0.0042
Trypanosoma brucei unspecified product 0.0093 0.0237 0.0882
Trypanosoma brucei calpain-like cysteine peptidase, putative 0.011 0.029 0.108
Loa Loa (eye worm) hypothetical protein 0.0022 0.0007 0.0018
Loa Loa (eye worm) hypothetical protein 0.0049 0.0093 0.0317
Mycobacterium tuberculosis Probable chain -fatty-acid-CoA ligase FadD13 (fatty-acyl-CoA synthetase) 0.0049 0.0093 0.0756
Echinococcus multilocularis chromodomain helicase DNA binding protein 1 0.0057 0.0121 0.0132
Entamoeba histolytica tumor susceptibility gene 101 protein, putative 0.0047 0.0089 0.0261
Schistosoma mansoni FTZ-F1 nuclear receptor-like protein 0.0061 0.0133 0.0147
Echinococcus multilocularis beta adrenergic receptor kinase 0.0021 0.0004 0.0002
Leishmania major isocitrate dehydrogenase [NADP], mitochondrial precursor, putative 0.0031 0.0037 0.0124
Loa Loa (eye worm) hypothetical protein 0.0176 0.0503 0.1751
Schistosoma mansoni Mername-AA248 (C02 family) 0.0021 0.0004 0.0004
Mycobacterium ulcerans exodeoxyribonuclease III protein XthA 0.0057 0.0121 0.0709
Loa Loa (eye worm) TK/INSR protein kinase 0.0047 0.0088 0.0299
Echinococcus multilocularis PWWP domain containing protein 2A 0.0029 0.0031 0.0032
Entamoeba histolytica hypothetical protein 0.0309 0.0929 0.2714
Trichomonas vaginalis Importin beta-1 subunit, putative 0.0023 0.0011 0.003
Brugia malayi calpain family protein 1 0.007 0.0161 0.0222
Echinococcus granulosus tumor protein p63 0.0332 0.1003 0.1111
Mycobacterium ulcerans long-chain-fatty-acid-CoA ligase 0.0049 0.0093 0.054
Trypanosoma cruzi calpain-like cysteine peptidase, putative 0.0021 0.0004 0.0006
Trypanosoma brucei flap endonuclease-1 (FEN-1), putative 0.0108 0.0282 0.1052
Brugia malayi PHD-finger family protein 0.0032 0.004 0.0055
Loa Loa (eye worm) hypothetical protein 0.0032 0.0041 0.0134
Onchocerca volvulus 0.0038 0.0059 0.0057
Onchocerca volvulus 0.0029 0.003 0.0027
Trypanosoma brucei hypothetical protein, conserved 0.0042 0.0072 0.0267
Trichomonas vaginalis phosphoglycerate kinase, putative 0.0171 0.0484 0.159
Echinococcus granulosus flap endonuclease 1 0.0108 0.0282 0.031
Trypanosoma brucei importin beta-1 subunit, putative 0.0028 0.0029 0.0105
Loa Loa (eye worm) hypothetical protein 0.0029 0.003 0.0095
Toxoplasma gondii PHD-finger domain-containing protein 0.006 0.0131 0.0486
Mycobacterium tuberculosis Probable phosphoglycerate kinase Pgk 0.0171 0.0484 0.4716
Onchocerca volvulus 0.0146 0.0404 0.0402
Brugia malayi Pax transcription activation domain interacting protein 0.002 0.0002 0.0003
Echinococcus multilocularis Nuclear hormone receptor HR96 0.0029 0.003 0.003
Trichomonas vaginalis PIKK family atypical protein kinase 0.0024 0.0014 0.0037
Brugia malayi Pre-SET motif family protein 0.0127 0.0344 0.0475
Mycobacterium tuberculosis Probable fatty-acid-CoA ligase FadD5 (fatty-acid-CoA synthetase) (fatty-acid-CoA synthase) 0.0034 0.0047 0.0293
Echinococcus granulosus Ankyrin repeat domain containing protein 0.0088 0.022 0.0242
Echinococcus granulosus mixed lineage leukemia protein mll 0.0037 0.0055 0.0058
Entamoeba histolytica hypothetical protein 0.0029 0.0031 0.009
Echinococcus granulosus histone acetyltransferase MYST2 0.017 0.0482 0.0533
Schistosoma mansoni transcription factor LCR-F1 0.0146 0.0404 0.0448
Toxoplasma gondii isocitrate dehydrogenase 0.0031 0.0037 0.0137
Schistosoma mansoni nuclear receptor 0.0029 0.003 0.0033
Leishmania major peptidyl-prolyl cis-trans isomerase/rotamase, putative,PPIase, putative 0.0033 0.0042 0.0143
Trichomonas vaginalis lymphoid specific helicase, putative 0.0032 0.0041 0.0128
Echinococcus granulosus histone lysine N methyltransferase MLL3 0.0037 0.0055 0.0058
Schistosoma mansoni hypothetical protein 0.006 0.0131 0.0145
Echinococcus multilocularis calpain 0.0021 0.0004 0.0002
Loa Loa (eye worm) hypothetical protein 0.007 0.0161 0.0555
Mycobacterium ulcerans glutaminase 0.0544 0.1682 1
Trichomonas vaginalis phosphoglycerate kinase, putative 0.0171 0.0484 0.159
Leishmania major target of rapamycin kinase (TOR) kinase 3 0.0035 0.005 0.0172
Echinococcus multilocularis NADP dependent isocitrate dehydrogenase 0.0031 0.0037 0.0039
Echinococcus granulosus snurportin 1 0.0304 0.0913 0.101
Trichomonas vaginalis CAMK family protein kinase 0.0098 0.0252 0.0823
Echinococcus granulosus expressed protein 0.0033 0.0045 0.0047
Echinococcus multilocularis NADP dependent isocitrate dehydrogenase 0.0031 0.0037 0.0039
Onchocerca volvulus 0.0049 0.0094 0.0092
Treponema pallidum fructose-bisphosphate aldolase 0.0604 0.1874 1
Plasmodium falciparum phosphoglycerate kinase 0.0171 0.0484 0.1808
Plasmodium vivax acyl-CoA synthetase, putative 0.0036 0.0054 0.0192
Brugia malayi RNA binding protein 0.0137 0.0376 0.0519
Loa Loa (eye worm) hypothetical protein 0.0039 0.0063 0.0213
Plasmodium vivax isocitrate dehydrogenase [NADP], mitochondrial, putative 0.0031 0.0037 0.013
Trypanosoma cruzi peptidyl-prolyl cis-trans isomerase 0.0033 0.0042 0.0149
Schistosoma mansoni protein kinase 0.0082 0.02 0.0222
Brugia malayi Nuclear hormone receptor family member nhr-40 0.0061 0.0133 0.0183
Schistosoma mansoni serine/threonine protein kinase 0.0021 0.0004 0.0005
Brugia malayi SWIRM domain containing protein 0.0025 0.0018 0.0025
Brugia malayi CXXC zinc finger family protein 0.0149 0.0415 0.0574
Schistosoma mansoni chromobox protein 0.0293 0.0878 0.0974
Trypanosoma cruzi DNA polymerase kappa, putative 0.0164 0.0463 0.1721
Schistosoma mansoni hypothetical protein 0.0023 0.0012 0.0013
Echinococcus granulosus methyl CpG binding domain protein 2 0.0052 0.0105 0.0114
Mycobacterium leprae possible inositol monophosphatase SubH (IMPase) (inositol-1-phosphatase) (I-1-Pase ). 0.0036 0.0052 0.0565
Brugia malayi RNase H family protein 0.0113 0.0298 0.0412
Onchocerca volvulus Heterochromatin protein 1 homolog 0.0169 0.048 0.0478
Echinococcus granulosus thyroid hormone receptor alpha 0.0029 0.003 0.003
Schistosoma mansoni chromodomain helicase DNA binding protein 0.0057 0.0121 0.0135
Echinococcus multilocularis fetal alzheimer antigen, falz 0.0076 0.018 0.0198
Echinococcus multilocularis epidermal growth factor receptor 0.0079 0.019 0.0208
Plasmodium falciparum ADP-dependent DNA helicase RecQ 0.0124 0.0334 0.1248
Trichomonas vaginalis hypothetical protein 0.0034 0.0046 0.0145
Toxoplasma gondii inositol(myo)-1(or 4)-monophosphatase 2, putative 0.004 0.0066 0.0243
Entamoeba histolytica peptidyl-prolyl cis-trans isomerase, putative 0.0033 0.0042 0.0123
Trichomonas vaginalis chromobox protein, putative 0.0293 0.0878 0.289
Trichomonas vaginalis CMGC family protein kinase 0.0106 0.0279 0.0912
Trichomonas vaginalis CMGC family protein kinase 0.0106 0.0279 0.0912
Brugia malayi nuclear receptor RXR 0.0032 0.0041 0.0055
Brugia malayi Nuclear hormone receptor family member nhr-31 0.0061 0.0133 0.0183
Echinococcus granulosus protein quaking 0.0027 0.0023 0.0023
Loa Loa (eye worm) RecQ helicase 0.0138 0.038 0.132
Echinococcus multilocularis exonuclease 1 0.0022 0.0007 0.0006
Echinococcus multilocularis disco interacting protein 2 0.004 0.0066 0.007
Schistosoma mansoni myelin transcription factor 1 myt1 0.017 0.0482 0.0535
Trichomonas vaginalis phosphofructokinase, putative 0.0107 0.0279 0.0914
Trypanosoma cruzi phosphoglycerate kinase, putative 0.0171 0.0484 0.1801
Brugia malayi tumor suppressor. 0.0316 0.095 0.1313
Plasmodium falciparum protoporphyrinogen oxidase 0.0025 0.0018 0.0068
Plasmodium vivax heterochromatin protein 1, putative 0.0057 0.0121 0.0445
Echinococcus multilocularis flap endonuclease GEN 1 0.0022 0.0007 0.0006
Onchocerca volvulus 0.0184 0.0528 0.0526
Trypanosoma cruzi peptidyl-prolyl cis-trans isomerase 0.0033 0.0042 0.0149
Loa Loa (eye worm) PHD-finger family protein 0.0063 0.014 0.0483
Schistosoma mansoni tyrosine kinase 0.0079 0.019 0.0211
Schistosoma mansoni serine/threonine protein kinase 0.0197 0.0568 0.063
Entamoeba histolytica hypothetical protein 0.0146 0.0404 0.1181
Loa Loa (eye worm) Pin1-type peptidyl-prolyl cis-trans isomerase 0.0033 0.0045 0.0148
Trypanosoma cruzi UDP-galactopyranose mutase 0.0025 0.0018 0.006
Leishmania major hypothetical protein, conserved 0.0029 0.0031 0.01
Trypanosoma cruzi cysteine peptidase, Clan CA, family C2, putative 0.0021 0.0004 0.0006
Schistosoma mansoni tyrosine kinase 0.0079 0.019 0.0211
Brugia malayi hypothetical protein 0.0471 0.1447 0.2002
Trichomonas vaginalis PIKK family atypical protein kinase 0.0024 0.0014 0.0037
Brugia malayi Intermediate filament tail domain containing protein 0.0081 0.0198 0.0274
Trypanosoma cruzi DNA polymerase kappa, putative 0.0164 0.0463 0.1721
Trypanosoma brucei unspecified product 0.0157 0.044 0.1642
Leishmania major hypothetical protein, conserved 0.0022 0.0007 0.0013
Trichomonas vaginalis DNA helicase recq, putative 0.0084 0.0205 0.0669
Leishmania major telomerase reverse transcriptase, putative 0.0855 0.2677 1
Echinococcus granulosus transcription factor Dp 1 0.0038 0.0058 0.0062
Echinococcus granulosus chromobox protein 2 0.0057 0.0121 0.0132
Entamoeba histolytica tyrosyl-DNA phosphodiesterase, putative 0.0065 0.0146 0.0426
Schistosoma mansoni histone-lysine n-methyltransferase setb1 0.0179 0.0512 0.0568
Echinococcus multilocularis zinc finger protein 0.007 0.0163 0.0178
Trypanosoma cruzi target of rapamycin kinase 3 0.0035 0.005 0.0178
Brugia malayi tailless protein 0.0029 0.003 0.004
Leishmania major hypothetical protein, conserved 0.0022 0.0009 0.0018
Trichomonas vaginalis fructose-bisphosphate aldolase, putative 0.0604 0.1874 0.6178
Brugia malayi BRM protein 0.0145 0.0402 0.0556
Treponema pallidum ATP-dependent DNA helicase 0.0035 0.0051 0.0258
Trypanosoma cruzi mitogen-activated protein kinase 11, putative 0.0106 0.0279 0.1033
Entamoeba histolytica DNA repair and recombination protein RAD52, putative 0.1087 0.3422 1
Trichomonas vaginalis conserved hypothetical protein 0.0026 0.0022 0.0063
Trichomonas vaginalis chromodomain-helicase-DNA-binding protein, putative 0.0084 0.0206 0.0671
Brugia malayi 6-phosphofructokinase 0.0107 0.0279 0.0386
Trypanosoma brucei calpain-like protein, putative 0.0021 0.0004 0.0013
Loa Loa (eye worm) hypothetical protein 0.0311 0.0935 0.3265
Trypanosoma cruzi hypothetical protein, conserved 0.0029 0.0031 0.0106
Entamoeba histolytica hypothetical protein 0.0023 0.0011 0.0033
Trichomonas vaginalis chromobox protein, putative 0.0181 0.0519 0.1705
Brugia malayi Amyloid A4 extracellular domain containing protein 0.03 0.09 0.1244
Loa Loa (eye worm) hypothetical protein 0.0471 0.1447 0.5057
Brugia malayi Temporarily assigned gene name protein 44 0.0027 0.0023 0.0031
Brugia malayi glutaminase DH11.1 0.0544 0.1682 0.2326
Echinococcus granulosus suppression of tumorigenicity 18 protein 0.017 0.0482 0.0533
Schistosoma mansoni DNA polymerase IV / kappa 0.0042 0.0072 0.008
Schistosoma mansoni tyrosine kinase 0.0047 0.0088 0.0097
Schistosoma mansoni hypothetical protein 0.0027 0.0023 0.0026
Schistosoma mansoni Protoporphyrinogen oxidase chloroplast/mitochondrial precursor 0.0025 0.0018 0.002
Trypanosoma brucei DNA polymerase eta, putative 0.0188 0.0541 0.2019
Echinococcus granulosus jumonji domain containing protein 0.0084 0.0206 0.0226
Schistosoma mansoni hypothetical protein 0.0422 0.129 0.1432
Toxoplasma gondii XPG N-terminal domain-containing protein 0.0022 0.0007 0.0026
Plasmodium vivax exonuclease I, putative 0.0022 0.0007 0.0019
Entamoeba histolytica phosphatidylinositol3-kinaseTor2, putative 0.0044 0.0079 0.023
Brugia malayi XPG I-region family protein 0.0022 0.0007 0.001
Loa Loa (eye worm) hypothetical protein 0.017 0.0482 0.168
Trichomonas vaginalis PIKK family atypical protein kinase 0.0024 0.0014 0.0037
Mycobacterium ulcerans flavin-containing monoamine oxidase AofH 0.0359 0.1087 0.646
Trichomonas vaginalis phosphofructokinase, putative 0.0029 0.003 0.009
Entamoeba histolytica deoxycytidyl transferase, putative 0.0135 0.0371 0.1085
Trypanosoma cruzi 3-phosphoglycerate kinase, glycosomal 0.0063 0.0138 0.0507
Schistosoma mansoni smad1 5 8 and 0.0025 0.0019 0.0021
Loa Loa (eye worm) hypothetical protein 0.0141 0.039 0.1356
Mycobacterium ulcerans DNA polymerase IV 0.0164 0.0463 0.2742
Echinococcus granulosus ecdysone induced protein 78C 0.0061 0.0133 0.0145
Brugia malayi jmjC domain containing protein 0.0197 0.057 0.0788
Leishmania major ATP-dependent DEAD/H DNA helicase recQ, putative 0.0084 0.0205 0.0753
Trypanosoma cruzi kinesin, putative 0.0021 0.0004 0.0006
Echinococcus multilocularis regulator of G protein signaling 7 0.0028 0.0028 0.0028
Schistosoma mansoni DNA helicase recq1 0.0069 0.016 0.0177
Toxoplasma gondii exonuclease III APE 0.0057 0.0121 0.0452
Brugia malayi calpain 5 0.0021 0.0004 0.0005
Toxoplasma gondii HEAT repeat-containing protein 0.0028 0.0029 0.0105
Trichomonas vaginalis chromodomain helicase DNA binding protein, putative 0.0084 0.0206 0.0671
Schistosoma mansoni nuclear hormone receptor superfamily protein-related 0.0029 0.003 0.0033
Toxoplasma gondii chromodomain helicase DNA binding protein CHD1/SWI2/SNF2 0.0057 0.0121 0.0451
Echinococcus granulosus mothers against decapentaplegic 5 0.0025 0.0019 0.0018
Loa Loa (eye worm) hypothetical protein 0.0063 0.0141 0.0484
Echinococcus multilocularis isocitrate dehydrogenase 0.0031 0.0037 0.0039
Loa Loa (eye worm) hypothetical protein 0.0315 0.0948 0.3309
Loa Loa (eye worm) hypothetical protein 0.0061 0.0133 0.0456
Trypanosoma cruzi mitochondrial DNA polymerase beta-PAK, putative 0.0284 0.0849 0.3167
Trichomonas vaginalis PIKK family atypical protein kinase 0.0024 0.0014 0.0037
Leishmania major DNA polymerase kappa, putative 0.0142 0.0394 0.1459
Loa Loa (eye worm) CMGC/MAPK/ERK1 protein kinase 0.0106 0.0279 0.0967
Trichomonas vaginalis PIKK family atypical protein kinase 0.0044 0.0079 0.0252
Plasmodium vivax hypothetical protein, conserved 0.0057 0.0121 0.0445
Loa Loa (eye worm) hypothetical protein 0.0118 0.0315 0.1094
Brugia malayi hypothetical protein 0.0146 0.0404 0.0558
Trypanosoma cruzi calpain-like cysteine peptidase, putative 0.0021 0.0004 0.0006
Schistosoma mansoni jumonji/arid domain-containing protein 0.0085 0.0211 0.0234
Echinococcus multilocularis 0.0025 0.0018 0.0018
Brugia malayi hypothetical protein 0.0025 0.0018 0.0025
Brugia malayi ecdysone receptor 0.0029 0.003 0.004
Trypanosoma cruzi mitogen activated protein kinase 4, putative 0.0106 0.0279 0.1033
Plasmodium vivax DEAD/DEAH helicase, putative 0.0021 0.0006 0.0014
Loa Loa (eye worm) hypothetical protein 0.0029 0.003 0.0095
Plasmodium vivax telomerase reverse transcriptase, putative 0.0855 0.2677 1
Trypanosoma cruzi mitochondrial DNA polymerase beta, putative 0.0601 0.1865 0.6961
Mycobacterium tuberculosis Probable fructose-bisphosphate aldolase Fba 0.0295 0.0883 0.8758
Echinococcus granulosus family C2 unassigned peptidase C02 family 0.0073 0.0172 0.0189
Brugia malayi conserved hypotetical protein 0.0029 0.003 0.004
Echinococcus granulosus nuclear receptor nhr 48 0.0029 0.003 0.003
Schistosoma mansoni NADP-specific isocitrate dehydrogenase 0.0031 0.0037 0.0041
Trichomonas vaginalis PIKK family atypical protein kinase 0.0035 0.005 0.0157
Plasmodium falciparum ataxin-2 like protein, putative 0.0052 0.0104 0.0387
Brugia malayi Nuclear hormone receptor family member nhr-14 0.0061 0.0133 0.0183
Brugia malayi hypothetical protein 0.0119 0.032 0.0442
Entamoeba histolytica chromodomain-helicase-DNA-binding protein, putative 0.0057 0.0121 0.0355
Loa Loa (eye worm) hypothetical protein 0.0029 0.0031 0.0099
Entamoeba histolytica hypothetical protein 0.0146 0.0404 0.1181
Trichomonas vaginalis flap endonuclease-1, putative 0.0022 0.0007 0.0017
Echinococcus granulosus lamin 0.0081 0.0198 0.0218
Brugia malayi hypothetical protein 0.002 0.0002 0.0003
Leishmania major tyrosyl-DNA phosphodiesterase 1 0.0065 0.0146 0.053
Loa Loa (eye worm) XPG I-region family protein 0.0022 0.0007 0.0018
Mycobacterium tuberculosis Conserved hypothetical protein 0.0135 0.0371 0.3572
Trypanosoma brucei DNA repair protein RAD2, putative 0.0022 0.0007 0.0026
Trypanosoma brucei DNA polymerase kappa, putative 0.0071 0.0164 0.061
Onchocerca volvulus 0.0149 0.0416 0.0414
Loa Loa (eye worm) steroid hormone receptor 0.0061 0.0133 0.0456
Echinococcus multilocularis Jumonji, AT rich interactive domain 1B 0.0032 0.004 0.0041
Mycobacterium tuberculosis Probable exodeoxyribonuclease III protein XthA (exonuclease III) (EXO III) (AP endonuclease VI) 0.0057 0.0121 0.1044
Loa Loa (eye worm) nuclear hormone receptor family member nhr-49 0.0061 0.0133 0.0456
Trypanosoma cruzi MIZ/SP-RING zinc finger, putative 0.0029 0.0031 0.0106
Echinococcus multilocularis lamin dm0 0.0081 0.0198 0.0218
Echinococcus multilocularis nuclear receptor 2DBD gamma 0.0029 0.003 0.003
Trichomonas vaginalis flap endonuclease-1, putative 0.0022 0.0007 0.0017
Echinococcus multilocularis FTZ F1 nuclear receptor protein 0.0061 0.0133 0.0145
Mycobacterium tuberculosis Probable isocitrate dehydrogenase [NADP] Icd1 (oxalosuccinate decarboxylase) (IDH) (NADP+-specific ICDH) (IDP) 0.0031 0.0037 0.0191
Schistosoma mansoni hepatoma derived growth factor 0.0029 0.0031 0.0034
Loa Loa (eye worm) G protein signaling regulator EGL-10 0.0028 0.0028 0.009
Brugia malayi Nuclear hormone receptor-like 1 0.0061 0.0133 0.0183
Plasmodium falciparum ATP-dependent DNA helicase Q1 0.0069 0.016 0.0596
Schistosoma mansoni tar DNA-binding protein 0.0137 0.0376 0.0417
Brugia malayi ATP dependent DNA ligase C terminal region family protein 0.002 0.0002 0.0003
Schistosoma mansoni DNA polymerase eta 0.0188 0.0541 0.06
Trichomonas vaginalis PIKK family atypical protein kinase 0.0038 0.0058 0.0184
Echinococcus granulosus smad 0.0025 0.0019 0.0018
Trichomonas vaginalis conserved hypothetical protein 0.0026 0.0022 0.0063
Toxoplasma gondii phosphoglycerate kinase PGKI 0.0171 0.0484 0.1807
Plasmodium vivax protoporphyrinogen oxidase, putative 0.0025 0.0018 0.006
Trichomonas vaginalis conserved hypothetical protein 0.0057 0.0121 0.0393
Trypanosoma cruzi phosphoglycerate kinase, putative 0.0063 0.0138 0.0507
Echinococcus multilocularis isocitrate dehydrogenase 2 (NADP+) 0.0031 0.0037 0.0039
Loa Loa (eye worm) hypothetical protein 0.0029 0.003 0.0095
Echinococcus granulosus peregrin 0.01 0.0259 0.0285
Trypanosoma brucei kinesin, putative 0.0021 0.0004 0.0013
Schistosoma mansoni rotamase 0.0033 0.0045 0.005
Schistosoma mansoni eyes absent homolog 0.0087 0.0215 0.0239
Echinococcus multilocularis calpain 7 (C02 family) 0.0021 0.0004 0.0002
Plasmodium vivax 6-phosphofructokinase, putative 0.0029 0.003 0.0102
Brugia malayi RNA recognition motif domain containing protein 0.0137 0.0376 0.0519
Schistosoma mansoni Smad4 0.0025 0.0019 0.0021
Schistosoma mansoni phosphoglucomutase 0.0113 0.0298 0.0331
Plasmodium vivax calpain, putative 0.0021 0.0004 0.0006
Brugia malayi hypothetical protein 0.007 0.0161 0.0222
Loa Loa (eye worm) calpain family protein 1 0.007 0.0161 0.0555
Onchocerca volvulus 0.0029 0.0031 0.0028
Giardia lamblia Endonuclease/Exonuclease/phosphatase 0.0057 0.0121 0.0348
Echinococcus granulosus lysine specific histone demethylase 1A 0.0025 0.0018 0.0018
Trypanosoma brucei exonuclease, putative 0.0022 0.0007 0.0026
Echinococcus granulosus cpg binding protein 0.0161 0.0455 0.0502
Trypanosoma brucei retrotransposon hot spot protein 4 (RHS4), interrupted 0.0122 0.0329 0.1226
Loa Loa (eye worm) hypothetical protein 0.0029 0.003 0.0095
Echinococcus multilocularis Basic leucine zipper (bZIP) transcription 0.0146 0.0404 0.0446
Echinococcus multilocularis transcription factor Dp 1 0.0038 0.0058 0.0062
Trichomonas vaginalis flap endonuclease-1, putative 0.0108 0.0282 0.0923
Trypanosoma brucei DNA polymerase kappa, putative 0.0071 0.0164 0.061
Schistosoma mansoni photoreceptor-specific nuclear receptor related 0.0061 0.0133 0.0147
Trichomonas vaginalis 6-phosphofructokinase, putative 0.0029 0.003 0.009
Brugia malayi Type III restriction enzyme, res subunit family protein 0.0057 0.0121 0.0167
Echinococcus multilocularis BRK domain containing protein 0.0024 0.0014 0.0013
Schistosoma mansoni 6-phosphofructokinase 0.0107 0.0279 0.031
Trichomonas vaginalis hypothetical protein 0.0057 0.0121 0.0393
Chlamydia trachomatis phosphoglycerate kinase 0.0171 0.0484 1
Schistosoma mansoni bromodomain-containing nuclear protein 1 brd1 0.006 0.0131 0.0145
Brugia malayi Nuclear hormone receptor E75 0.0029 0.003 0.004
Brugia malayi mbt repeat family protein 0.0149 0.0416 0.0575
Loa Loa (eye worm) nuclear hormone receptor 0.0029 0.003 0.0095
Brugia malayi GTP-binding regulatory protein Gs alpha-S chain, putative 0.0278 0.083 0.1147
Plasmodium falciparum acyl-CoA synthetase 0.0036 0.0054 0.02
Brugia malayi Phosphoglycerate kinase 0.0063 0.0138 0.019
Brugia malayi Protein kinase domain containing protein 0.0047 0.0088 0.0121
Loa Loa (eye worm) hypothetical protein 0.0061 0.0133 0.0456
Echinococcus granulosus epidermal growth factor receptor 0.0079 0.019 0.0208
Trichomonas vaginalis PIKK family atypical protein kinase 0.003 0.0032 0.0098
Trichomonas vaginalis chromobox protein, putative 0.0057 0.0121 0.0393
Schistosoma mansoni scm-relatedprotein containing 4 mbt domains (sfmbt) 0.0149 0.0416 0.0462
Entamoeba histolytica hypothetical protein 0.0057 0.0121 0.0355
Trichomonas vaginalis PIKK family atypical protein kinase 0.0033 0.0043 0.0133
Echinococcus multilocularis endonuclease exonuclease phosphatase 0.06 0.1861 0.2063
Schistosoma mansoni hypothetical protein 0.0146 0.0404 0.0448
Trypanosoma brucei DNA polymerase kappa, putative 0.0142 0.0394 0.147
Mycobacterium tuberculosis Probable 6-phosphofructokinase PfkA (phosphohexokinase) (phosphofructokinase) 0.0107 0.0279 0.2642
Mycobacterium tuberculosis Probable fatty-acid-CoA ligase FadD3 (fatty-acid-CoA synthetase) (fatty-acid-CoA synthase) 0.0034 0.0047 0.0293
Echinococcus granulosus GPCR family 2 0.0097 0.0249 0.0274
Echinococcus multilocularis FKBP12 rapamycin complex associated protein 0.0044 0.0079 0.0085
Trypanosoma brucei hypothetical protein, conserved 0.0122 0.0329 0.1226
Trichomonas vaginalis phosphofructokinase, putative 0.0107 0.0279 0.0914
Mycobacterium ulcerans 6-phosphofructokinase 0.0107 0.0279 0.1649
Plasmodium vivax 6-phosphofructokinase, putative 0.0029 0.003 0.0102
Trypanosoma cruzi PAS-domain containing phosphoglycerate kinase, putative 0.0063 0.0138 0.0507
Schistosoma mansoni hepatoma derived growth factor 0.0029 0.0031 0.0034
Trypanosoma cruzi cysteine peptidase, Clan CA, family C2, putative 0.0131 0.0356 0.1323
Loa Loa (eye worm) hypothetical protein 0.0127 0.0345 0.1198
Schistosoma mansoni tyrosine kinase 0.0078 0.0188 0.0208
Loa Loa (eye worm) CHromoDomain protein family member 0.007 0.0161 0.0556
Echinococcus multilocularis mothers against decapentaplegic 5 0.0025 0.0019 0.0018
Echinococcus multilocularis ATP dependent DNA helicase Q1 0.0069 0.016 0.0175
Schistosoma mansoni regulator of G protein signaling 0.0028 0.0028 0.0031
Trichomonas vaginalis fructose-bisphosphate aldolase, putative 0.0604 0.1874 0.6178
Trichomonas vaginalis conserved hypothetical protein 0.0057 0.0121 0.0393
Echinococcus multilocularis PHD finger protein rhinoceros 0.006 0.0131 0.0142
Schistosoma mansoni DNA ligase IV 0.002 0.0002 0.0003
Echinococcus multilocularis NADP dependent isocitrate dehydrogenase 0.0031 0.0037 0.0039
Loa Loa (eye worm) hypothetical protein 0.0022 0.0007 0.0018
Echinococcus multilocularis bromodomain adjacent to zinc finger domain 0.011 0.0291 0.032
Toxoplasma gondii PHD-finger domain-containing protein 0.006 0.0131 0.0486
Trichomonas vaginalis CAMK family protein kinase 0.0197 0.0568 0.1865
Schistosoma mansoni calpain (C02 family) 0.0021 0.0004 0.0004
Leishmania major calpain-like cysteine peptidase, putative,cysteine peptidase, Clan CA, family C2, putative 0.011 0.029 0.1069
Loa Loa (eye worm) STE/STE7/MEK1 protein kinase 0.0082 0.02 0.0692
Wolbachia endosymbiont of Brugia malayi ribonuclease HI 0.0113 0.0298 0.6138
Loa Loa (eye worm) hypothetical protein 0.0081 0.0198 0.0686
Loa Loa (eye worm) hypothetical protein 0.0071 0.0164 0.0564
Loa Loa (eye worm) nuclear hormone receptor-like 1 0.0032 0.0041 0.0134
Echinococcus granulosus FTZ F1 nuclear receptor protein 0.0061 0.0133 0.0145
Trypanosoma cruzi importin beta-1 subunit, putative 0.0023 0.0011 0.0034
Echinococcus granulosus calpain A 0.0073 0.0172 0.0189
Loa Loa (eye worm) transcription factor SMAD2 0.0373 0.1134 0.396
Trypanosoma cruzi hypothetical protein, conserved 0.0042 0.0072 0.026
Trichomonas vaginalis set domain proteins, putative 0.0965 0.3032 1
Schistosoma mansoni hypothetical protein 0.0029 0.0031 0.0034
Loa Loa (eye worm) TK/EGFR protein kinase 0.0147 0.0408 0.1419
Trypanosoma cruzi tyrosyl-DNA Phosphodiesterase (Tdp1), putative 0.0065 0.0146 0.0536
Echinococcus multilocularis Protein lozenge 0.0059 0.0127 0.0138
Loa Loa (eye worm) hypothetical protein 0.0049 0.0094 0.0322
Echinococcus multilocularis cytoplasmic intermediate filament protein 0.0039 0.0063 0.0068
Trypanosoma cruzi telomerase reverse transcriptase, putative 0.0855 0.2677 1
Echinococcus granulosus terminal deoxycytidyl transferase rev1 0.0135 0.0371 0.0409
Brugia malayi MH2 domain containing protein 0.0025 0.0019 0.0025
Loa Loa (eye worm) calpain 0.0021 0.0004 0.0005
Trichomonas vaginalis conserved hypothetical protein 0.0169 0.048 0.1578
Trypanosoma brucei DNA polymerase kappa, putative 0.01 0.0259 0.0967
Toxoplasma gondii poly(ADP-ribose) polymerase catalytic domain-containing protein 0.002 0.0002 0.0007
Loa Loa (eye worm) TAR-binding protein 0.0137 0.0376 0.1306
Echinococcus multilocularis thyroid hormone receptor alpha 0.0061 0.0133 0.0145
Schistosoma mansoni chromosome transmission fidelity factor 0.002 0.0002 0.0003
Brugia malayi DKFZp564C0469 protein 0.002 0.0002 0.0003
Trypanosoma brucei DNA polymerase kappa, putative 0.0164 0.0463 0.1727
Schistosoma mansoni nuclear hormone receptor 0.0029 0.003 0.0033
Trichomonas vaginalis phosphofructokinase, putative 0.0029 0.003 0.009
Echinococcus multilocularis jun protein 0.0181 0.0519 0.0573
Schistosoma mansoni terminal deoxycytidyl transferase 0.0135 0.0371 0.0412
Trypanosoma cruzi apurinic/apyrimidinic endonuclease 0.0057 0.0121 0.0445
Echinococcus granulosus dual specificity mitogen activated protein 0.0082 0.02 0.022
Trypanosoma brucei Phosphatidylinositol 3-kinase tor1 0.0044 0.0079 0.0292
Trypanosoma brucei phosphoglycerate kinase 0.0171 0.0484 0.1807
Schistosoma mansoni hypothetical protein 0.0027 0.0023 0.0026
Schistosoma mansoni methyl-cpg binding protein mbd 0.0052 0.0105 0.0117
Loa Loa (eye worm) hypothetical protein 0.0029 0.003 0.0095
Trypanosoma brucei calpain-like protein, putative 0.0021 0.0004 0.0013
Echinococcus granulosus inositol monophosphatase 1 0.004 0.0066 0.007
Mycobacterium leprae PROBABLE FATTY-ACID-CoA LIGASE FADD7 (FATTY-ACID-CoA SYNTHETASE) (FATTY-ACID-CoA SYNTHASE) 0.0049 0.0093 0.1029
Brugia malayi Nuclear hormone receptor E75 0.0029 0.003 0.004
Toxoplasma gondii ATP-dependent DNA helicase, RecQ family protein 0.0088 0.0221 0.0823
Echinococcus multilocularis calpain 5 0.0021 0.0004 0.0002
Schistosoma mansoni histone-lysine n-methyltransferase setb1 0.0127 0.0344 0.0382
Trichomonas vaginalis PIKK family atypical protein kinase 0.0035 0.005 0.0157
Schistosoma mansoni methyl-cpg binding protein mbd 0.0052 0.0105 0.0117
Brugia malayi Steroid receptor seven-up type 2 0.0061 0.0133 0.0183
Echinococcus multilocularis hypothetical protein 0.0021 0.0004 0.0002
Loa Loa (eye worm) hypothetical protein 0.021 0.061 0.2127
Trichomonas vaginalis chromodomain-helicase-DNA-binding protein, putative 0.0071 0.0167 0.0542
Echinococcus multilocularis muscleblind protein 1 0.0911 0.286 0.3172
Echinococcus granulosus nuclear receptor 2DBD gamma 0.0061 0.0133 0.0145
Plasmodium vivax SET domain protein, putative 0.0127 0.0344 0.1277
Onchocerca volvulus 0.0049 0.0093 0.0091
Brugia malayi nuclear hormone receptor family member odr-7 0.0029 0.003 0.004
Echinococcus granulosus calpain 5 0.0021 0.0004 0.0002
Brugia malayi steroid hormone receptor 0.0061 0.0133 0.0183
Schistosoma mansoni multiple ankyrin repeats single kh domain protein 0.0088 0.022 0.0244
Trichomonas vaginalis phosphofructokinase, putative 0.0029 0.003 0.009
Echinococcus multilocularis 0.0045 0.0083 0.009
Loa Loa (eye worm) PLK/PLK1 protein kinase 0.0197 0.0568 0.1978
Echinococcus multilocularis dna polymerase kappa 0.0164 0.0463 0.0511
Echinococcus multilocularis musashi 0.0081 0.0198 0.0218
Echinococcus multilocularis Basic leucine zipper (bZIP) transcription factor 0.0181 0.0519 0.0573
Schistosoma mansoni RAR-like nuclear receptor 0.0061 0.0133 0.0147
Loa Loa (eye worm) phosphofructokinase 0.0107 0.0279 0.0969
Plasmodium vivax lysine-specific histone demethylase 1, putative 0.0025 0.0018 0.006
Echinococcus multilocularis tumor susceptibility gene 101 protein 0.007 0.0161 0.0176
Brugia malayi Nuclear hormone receptor-like 1 0.0032 0.0041 0.0055
Toxoplasma gondii hypothetical protein 0.0084 0.0205 0.0766
Echinococcus granulosus microtubule associated protein 2 0.283 0.9012 1
Mycobacterium tuberculosis Possible DNA-damage-inducible protein P DinP (DNA polymerase V) (pol IV 2) (DNA nucleotidyltransferase (DNA-directed)) 0.0142 0.0394 0.3802
Echinococcus granulosus mitogen activated protein kinase 0.0106 0.0279 0.0307
Trypanosoma cruzi hypothetical protein, conserved 0.0029 0.0031 0.0106
Entamoeba histolytica recQ family helicase, putative 0.0084 0.0205 0.0599
Trypanosoma cruzi DNA damage repair protein, putative 0.0042 0.0072 0.026
Echinococcus multilocularis chromodomain helicase DNA binding protein 4 0.007 0.0161 0.0176
Treponema pallidum ribonuclease H (rnhA) 0.0113 0.0298 0.158
Brugia malayi nuclear receptor NHR-88 0.0029 0.003 0.004
Schistosoma mansoni thyroid hormone receptor 0.0061 0.0133 0.0147
Toxoplasma gondii peptidylprolyl isomerase 0.0033 0.0042 0.0156
Entamoeba histolytica recQ family helicase, putative 0.0034 0.0046 0.0135
Trypanosoma brucei DNA polymerase IV, putative 0.0164 0.0463 0.1727
Schistosoma mansoni steroid hormone receptor ad4bp 0.0061 0.0133 0.0147
Trypanosoma brucei antigen, putative 0.0021 0.0004 0.0013
Schistosoma mansoni exonuclease 0.0022 0.0007 0.0008
Loa Loa (eye worm) MH1 domain-containing protein 0.0025 0.0019 0.0058
Schistosoma mansoni jun-related protein 0.0147 0.041 0.0455
Echinococcus multilocularis lysine specific demethylase 5A 0.0073 0.0171 0.0187
Echinococcus multilocularis TGF beta signal transducer SmadC 0.0025 0.0019 0.0018
Schistosoma mansoni mixed-lineage leukemia protein mll 0.0024 0.0016 0.0017
Trypanosoma brucei hypothetical protein, conserved 0.0042 0.0072 0.0267
Entamoeba histolytica pyrophosphate-dependent phosphofructokinase 0.0029 0.003 0.0087
Echinococcus granulosus chromobox protein 1 0.0293 0.0878 0.0972
Loa Loa (eye worm) PHD-finger family protein 0.006 0.0131 0.0449
Trypanosoma brucei tyrosyl-DNA Phosphodiesterase (Tdp1), putative 0.0065 0.0146 0.0542
Brugia malayi Phosphoglycerate kinase 0.0171 0.0484 0.0669
Trichomonas vaginalis fructose-bisphosphate aldolase, putative 0.0604 0.1874 0.6178
Trichomonas vaginalis exonuclease%2C+putative 0.0022 0.0007 0.0017
Loa Loa (eye worm) exodeoxyribonuclease III family protein 0.0057 0.0121 0.0417
Echinococcus multilocularis lamin 0.0081 0.0198 0.0218
Trichomonas vaginalis conserved hypothetical protein 0.0169 0.048 0.1578
Trypanosoma brucei target of rapamycin kinase 3, putative 0.0035 0.005 0.0185
Brugia malayi Isocitrate dehydrogenase 0.0031 0.0037 0.0051
Trypanosoma cruzi ATP-dependent DEAD/H DNA helicase recQ, putative 0.0084 0.0205 0.0758
Plasmodium vivax hypothetical protein, conserved 0.0025 0.0018 0.006
Echinococcus granulosus diuretic hormone 44 receptor GPRdih2 0.0097 0.0249 0.0274
Leishmania major hypothetical protein, conserved 0.0052 0.0104 0.0373
Loa Loa (eye worm) hypothetical protein 0.0237 0.0696 0.2427
Echinococcus multilocularis Transcription factor, JmjC domain containing protein 0.0197 0.057 0.063
Plasmodium falciparum heterochromatin protein 1 0.0057 0.0121 0.0453
Plasmodium falciparum exonuclease I, putative 0.0022 0.0007 0.0028
Trypanosoma brucei calpain-like protein, putative 0.0131 0.0356 0.1329
Echinococcus granulosus dnaJ subfamily B 0.1651 0.523 0.5802
Plasmodium falciparum flap endonuclease 1 0.0108 0.0282 0.1053
Echinococcus granulosus ATP dependent DNA helicase Q1 0.0069 0.016 0.0175
Schistosoma mansoni rab geranylgeranyl transferase alpha subunit 0.0135 0.0371 0.0412
Schistosoma mansoni hypothetical protein 0.0063 0.014 0.0156
Giardia lamblia Ribonuclease H 0.0113 0.0298 0.0865
Trichomonas vaginalis DNA polymerase eta, putative 0.0164 0.0463 0.152
Echinococcus granulosus SAM and MBT domain containing protein 0.0149 0.0416 0.0459
Loa Loa (eye worm) hypothetical protein 0.0057 0.0121 0.0416
Loa Loa (eye worm) calpain 5 0.0021 0.0004 0.0005
Mycobacterium tuberculosis Probable fatty-acid-CoA ligase FadD7 (fatty-acid-CoA synthetase) (fatty-acid-CoA synthase) 0.0034 0.0047 0.0293
Giardia lamblia Sgs1 DNA helicase, putative 0.0069 0.016 0.046
Trichomonas vaginalis PIKK family atypical protein kinase 0.0033 0.0043 0.0133
Entamoeba histolytica Flap nuclease, putative 0.0108 0.0282 0.0824
Echinococcus multilocularis FTZ F1 alpha 0.0061 0.0133 0.0145
Echinococcus multilocularis cpg binding protein 0.0161 0.0455 0.0502
Loa Loa (eye worm) hypothetical protein 0.0038 0.0059 0.0197
Loa Loa (eye worm) hypothetical protein 0.0027 0.0023 0.0072
Echinococcus granulosus insulin receptor 0.0047 0.0088 0.0095
Loa Loa (eye worm) nuclear hormone receptor family member nhr-41 0.0061 0.0133 0.0456
Loa Loa (eye worm) hypothetical protein 0.0103 0.0269 0.0932
Trypanosoma brucei cysteine peptidase, Clan CA, family C2, putative 0.011 0.029 0.108
Trichomonas vaginalis glutaminase, putative 0.0544 0.1682 0.5543
Trypanosoma cruzi DNA damage repair protein, putative 0.0042 0.0072 0.026
Schistosoma mansoni tsg101-related 0.0058 0.0123 0.0137
Schistosoma mansoni zinc finger protein 0.007 0.0163 0.0181
Brugia malayi intermediate filament protein 0.0081 0.0198 0.0274
Plasmodium vivax hypothetical protein, conserved 0.0057 0.0121 0.0445
Plasmodium vivax DNA repair protein REV1, putative 0.0042 0.0072 0.026
Leishmania major calpain-like cysteine peptidase, putative,cysteine peptidase, Clan CA, family C2, putative 0.0131 0.0356 0.1318
Echinococcus multilocularis bloom syndrome protein 0.0138 0.038 0.0419
Echinococcus granulosus regulator of G protein signaling 7 0.0028 0.0028 0.0028
Loa Loa (eye worm) ATP-dependent DNA helicase 0.0069 0.016 0.055
Brugia malayi hypothetical protein 0.0027 0.0023 0.0031
Echinococcus multilocularis histone lysine methyltransferase setb histone lysine methyltransferase eggless 0.0179 0.0512 0.0565
Onchocerca volvulus Protein ultraspiracle homolog 0.0061 0.0133 0.013
Trichomonas vaginalis chromobox protein, putative 0.0181 0.0519 0.1705
Wolbachia endosymbiont of Brugia malayi phosphoglycerate kinase 0.0171 0.0484 1
Leishmania major calpain-like cysteine peptidase, putative,cysteine peptidase, Clan CA, family C2, putative 0.0131 0.0356 0.1318
Echinococcus granulosus ATP dependent DNA helicase Q5 0.0069 0.016 0.0175
Loa Loa (eye worm) GTP-binding regulatory protein Gs alpha-S chain 0.0278 0.083 0.2896
Brugia malayi hypothetical protein 0.0142 0.0394 0.0544
Echinococcus multilocularis methyl CpG binding domain protein 2 0.0052 0.0105 0.0114
Trypanosoma cruzi PAS-domain containing phosphoglycerate kinase, putative 0.0063 0.0138 0.0507
Trichomonas vaginalis CAMK family protein kinase 0.0197 0.0568 0.1865
Trypanosoma brucei RNA helicase, putative 0.0422 0.129 0.4818
Echinococcus granulosus bromodomain adjacent to zinc finger domain 0.011 0.0291 0.032
Trichomonas vaginalis PIKK family atypical protein kinase 0.0026 0.0022 0.0064
Brugia malayi MH1 domain containing protein 0.0025 0.0019 0.0025
Brugia malayi serine/threonine-protein kinase plk-2 0.0197 0.0568 0.0784
Trichomonas vaginalis chromodomain helicase DNA binding protein, putative 0.0057 0.0121 0.0393
Echinococcus multilocularis dnaJ subfamily B 0.1651 0.523 0.5802
Trypanosoma cruzi DNA polymerase kappa, putative 0.0164 0.0463 0.1721
Toxoplasma gondii phosphofructokinase PFKII 0.0029 0.003 0.0109
Echinococcus multilocularis epidermal growth factor receptor 0.0147 0.0408 0.045
Loa Loa (eye worm) jmjC domain-containing protein 0.0124 0.0336 0.1168
Loa Loa (eye worm) inositol-1 0.004 0.0066 0.0221
Schistosoma mansoni acetyl-CoA C-acetyltransferase 0.0076 0.018 0.02
Brugia malayi nuclear receptor NHR-67 0.0029 0.003 0.004
Trypanosoma cruzi isocitrate dehydrogenase, putative 0.0031 0.0037 0.013
Schistosoma mansoni ap endonuclease 0.0057 0.0121 0.0135
Echinococcus granulosus FTZ F1 alpha 0.0061 0.0133 0.0145
Trichomonas vaginalis replication factor C large subunit, putative 0.002 0.0002 0.00000057814
Loa Loa (eye worm) hypothetical protein 0.0061 0.0133 0.0456
Onchocerca volvulus 0.0029 0.0031 0.0028
Schistosoma mansoni cpg binding protein 0.0149 0.0415 0.0461
Echinococcus multilocularis Ankyrin repeat domain containing protein 0.0088 0.022 0.0242
Loa Loa (eye worm) hypothetical protein 0.0028 0.0028 0.009
Echinococcus granulosus hepatoma derived growth factor protein 0.0029 0.0031 0.0032
Mycobacterium ulcerans extragenic suppressor protein SuhB 0.004 0.0066 0.0377
Leishmania major mitochondrial DNA polymerase beta-PAK, putative 0.0284 0.0849 0.3163
Loa Loa (eye worm) calpain family protein 1 0.0049 0.0094 0.0322
Trypanosoma brucei mitochondrial DNA polymerase beta-PAK 0.0284 0.0849 0.3171
Entamoeba histolytica hypothetical protein 0.0146 0.0404 0.1181
Loa Loa (eye worm) hypothetical protein 0.0036 0.0054 0.0179
Loa Loa (eye worm) hypothetical protein 0.0029 0.003 0.0095
Trypanosoma cruzi mitogen activated protein kinase 2, putative 0.0106 0.0279 0.1033
Loa Loa (eye worm) MBCTL1 0.017 0.0482 0.168
Echinococcus granulosus histone lysine methyltransferase setb 0.0179 0.0512 0.0565
Schistosoma mansoni ap endonuclease 0.0057 0.0121 0.0135
Schistosoma mansoni importin beta-1 0.0028 0.0029 0.0032
Entamoeba histolytica acyl-CoA synthetase, putative 0.0049 0.0093 0.0272
Trypanosoma brucei telomerase reverse transcriptase 0.0855 0.2677 1
Trypanosoma brucei inositol-1(or 4)-monophosphatase 1, putative 0.004 0.0066 0.0243
Onchocerca volvulus 0.0146 0.0404 0.0402
Trypanosoma brucei chrX additional, unordered contigs 0.0042 0.0072 0.0267
Schistosoma mansoni tyrosyl-DNA phosphodiesterase 0.0065 0.0146 0.0162
Brugia malayi Corticotropin releasing factor receptor 2 precursor, putative 0.0307 0.0922 0.1274
Loa Loa (eye worm) cytoplasmic intermediate filament protein 0.0044 0.0077 0.0262
Trichomonas vaginalis ap endonuclease, putative 0.0057 0.0121 0.0393
Loa Loa (eye worm) hypothetical protein 0.0025 0.0018 0.0056
Leishmania major mitogen activated protein kinase, putative,map kinase, putative 0.0106 0.0279 0.1028
Echinococcus multilocularis nuclear receptor subfamily 4 group A 0.0029 0.003 0.003
Brugia malayi hypothetical protein 0.0029 0.0031 0.0042
Echinococcus granulosus jun protein 0.0181 0.0519 0.0573
Schistosoma mansoni tar DNA-binding protein 0.0137 0.0376 0.0417
Schistosoma mansoni chromobox protein-related (chromobox 1) (heterochromatin 1) 0.0057 0.0121 0.0135
Leishmania major phosphoglycerate kinase C, glycosomal 0.0171 0.0484 0.1796
Onchocerca volvulus 0.0471 0.1447 0.1445
Brugia malayi Calcitonin receptor-like protein seb-1 0.0307 0.0922 0.1274
Schistosoma mansoni Tr4/Tr2 (homologue) 0.0061 0.0133 0.0147
Entamoeba histolytica acyl-CoA synthetase, putative 0.0049 0.0093 0.0272
Brugia malayi ImpB/MucB/SamB family protein 0.0135 0.0371 0.0513
Brugia malayi calpain 7 0.0021 0.0004 0.0005
Brugia malayi ecdysteroid receptor 0.0061 0.0133 0.0183
Echinococcus granulosus tar DNA binding protein 0.0137 0.0376 0.0414
Trypanosoma cruzi hypothetical protein, conserved 0.0022 0.0007 0.0019
Entamoeba histolytica phosphofructokinase, putative 0.0107 0.0279 0.0816
Mycobacterium ulcerans dehydrogenase 0.0025 0.0018 0.0095
Loa Loa (eye worm) hypothetical protein 0.0061 0.0133 0.0456
Schistosoma mansoni cellular tumor antigen P53 0.0049 0.0093 0.0104
Echinococcus multilocularis hepatocyte nuclear factor 4 alpha 0.0061 0.0133 0.0145
Plasmodium falciparum conserved Plasmodium membrane protein, unknown function 0.0027 0.0023 0.0087
Echinococcus granulosus PWWP domain containing protein 2A 0.0029 0.0031 0.0032
Schistosoma mansoni lamin 0.0081 0.0198 0.022
Schistosoma mansoni hypothetical protein 0.1651 0.523 0.5803
Echinococcus granulosus fetal alzheimer antigen falz 0.0076 0.018 0.0198
Trichomonas vaginalis fructose-bisphosphate aldolase, putative 0.0604 0.1874 0.6178
Brugia malayi Ligand-binding domain of nuclear hormone receptor family protein 0.0061 0.0133 0.0183
Brugia malayi hypothetical protein 0.0146 0.0404 0.0558
Trypanosoma brucei phosphoglycerate kinase 0.0171 0.0484 0.1807
Echinococcus granulosus guanine nucleotide binding protein Gs subunit 0.0278 0.083 0.0918
Plasmodium falciparum telomerase reverse transcriptase 0.0855 0.2677 1
Echinococcus multilocularis mitogen activated protein kinase 0.0106 0.0279 0.0307
Schistosoma mansoni zinc finger protein 0.0047 0.0088 0.0098
Treponema pallidum diphosphate--fructose-6-phosphate 1-phosphotransferase 0.0029 0.003 0.0146
Echinococcus multilocularis Nuclear hormone receptor HR96 0.0029 0.003 0.003
Plasmodium falciparum replication factor C subunit 1, putative 0.002 0.0002 0.0009
Brugia malayi SET domain containing protein 0.0027 0.0025 0.0033
Trichomonas vaginalis conserved hypothetical protein 0.0026 0.0022 0.0063
Brugia malayi C2-HC type zinc finger protein C.e-MyT1 0.017 0.0482 0.0667
Schistosoma mansoni coup transcription factor 0.0061 0.0133 0.0147
Loa Loa (eye worm) hypothetical protein 0.0035 0.0051 0.0169
Onchocerca volvulus 0.0029 0.003 0.0027
Trypanosoma brucei mitogen activated protein kinase 4, putative 0.0106 0.0279 0.1039
Schistosoma mansoni smad1 5 8 and 0.0025 0.0019 0.0021
Loa Loa (eye worm) hypothetical protein 0.0061 0.0133 0.0456
Trichomonas vaginalis phosphofructokinase, putative 0.0029 0.003 0.009
Echinococcus multilocularis BRK domain containing protein 0.0024 0.0014 0.0013
Giardia lamblia DINP protein human, muc B family 0.0142 0.0394 0.1145
Trypanosoma cruzi hypothetical protein, conserved 0.0042 0.0072 0.026
Trypanosoma cruzi ISWI complex protein 0.0047 0.0088 0.032
Echinococcus multilocularis neuropeptide receptor A26 0.0493 0.1518 0.1682
Loa Loa (eye worm) hypothetical protein 0.0061 0.0133 0.0456
Brugia malayi hypothetical protein 0.0033 0.0045 0.0061
Schistosoma mansoni zinc finger protein 0.0029 0.003 0.0033
Trypanosoma brucei DNA polymerase kappa, putative 0.0164 0.0463 0.1727
Echinococcus multilocularis guanine nucleotide binding protein G(s) subunit 0.0278 0.083 0.0918
Plasmodium vivax phosphoglycerate kinase, putative 0.0171 0.0484 0.1801
Toxoplasma gondii XPG N-terminal domain-containing protein 0.0022 0.0007 0.0026
Trypanosoma brucei hypothetical protein 0.011 0.029 0.108
Trypanosoma brucei unspecified product 0.0122 0.0329 0.1226
Brugia malayi jmjC domain containing protein 0.0085 0.0211 0.0291
Toxoplasma gondii SWI2/SNF2 Brahma-like putative 0.0032 0.0041 0.0152
Schistosoma mansoni phosphoglucomutase 0.0113 0.0298 0.0331
Trichomonas vaginalis conserved hypothetical protein 0.0026 0.0022 0.0063
Schistosoma mansoni retinoid-x-receptor (RXR) 0.0032 0.0041 0.0045
Loa Loa (eye worm) hypothetical protein 0.0171 0.0484 0.1686
Schistosoma mansoni hypothetical protein 0.0047 0.0088 0.0098
Trypanosoma brucei polo-like protein kinase 0.0197 0.0568 0.2118
Trichomonas vaginalis PIKK family atypical protein kinase 0.0026 0.0021 0.0062
Plasmodium vivax ATP-dependent DNA helicase Q1, putative 0.0034 0.0046 0.0164
Schistosoma mansoni SET domain protein 0.0052 0.0104 0.0115
Echinococcus granulosus PWWP domain containing protein 2A 0.0029 0.0031 0.0032
Toxoplasma gondii flap structure-specific endonuclease 1, putative 0.0108 0.0282 0.1052
Trypanosoma cruzi Phosphatidylinositol 3-kinase tor1 0.0044 0.0079 0.0286
Loa Loa (eye worm) nuclear hormone receptor family member nhr-40 0.0061 0.0133 0.0456
Mycobacterium ulcerans phosphoglycerate kinase 0.0171 0.0484 0.2869
Trypanosoma brucei DNA damage repair protein, putative 0.0042 0.0072 0.0267
Loa Loa (eye worm) hypothetical protein 0.0217 0.0633 0.2208
Entamoeba histolytica fructose-1,6-bisphosphate aldolase, putative 0.0604 0.1874 0.5477
Loa Loa (eye worm) hypothetical protein 0.0032 0.004 0.0133
Schistosoma mansoni alzheimer's disease beta-amyloid related 0.0109 0.0288 0.032
Trichomonas vaginalis inositol monophosphatase, putative 0.004 0.0066 0.0209
Trypanosoma brucei phosphatidylinositol 4-kinase, putative 0.0044 0.0079 0.0292
Brugia malayi Nuclear hormone receptor family member nhr-19 0.0061 0.0133 0.0183
Loa Loa (eye worm) phosphatidylinositol 3 0.0044 0.0079 0.0267
Loa Loa (eye worm) histone methyltransferase 0.0044 0.0077 0.0262
Brugia malayi Tyrosyl-DNA phosphodiesterase family protein 0.0065 0.0146 0.0201
Trypanosoma cruzi isocitrate dehydrogenase [NADP], mitochondrial precursor, putative 0.0031 0.0037 0.013
Entamoeba histolytica FKBP-rapamycin associated protein (FRAP), putative 0.0044 0.0079 0.023
Loa Loa (eye worm) hypothetical protein 0.0023 0.0012 0.0035
Trichomonas vaginalis conserved hypothetical protein 0.0026 0.0022 0.0063
Schistosoma mansoni calpain C (C02 family) 0.0021 0.0004 0.0004
Schistosoma mansoni nuclear hormone receptor nor-1/nor-2 0.0061 0.0133 0.0147
Trichomonas vaginalis DNA helicase recq1, putative 0.0138 0.038 0.1245
Loa Loa (eye worm) hypothetical protein 0.0032 0.0041 0.0134
Trichomonas vaginalis conserved hypothetical protein 0.0057 0.0121 0.0393
Brugia malayi nuclear receptor NHR-88 0.0061 0.0133 0.0183
Trichomonas vaginalis DNA helicase recq, putative 0.0138 0.038 0.1245
Mycobacterium leprae PROBABLE FATTY-ACID-CoA LIGASE FADD2 (FATTY-ACID-CoA SYNTHETASE) (FATTY-ACID-CoA SYNTHASE) 0.0049 0.0093 0.1029
Loa Loa (eye worm) intermediate filament tail domain-containing protein 0.0081 0.0198 0.0686
Echinococcus granulosus Basic leucine zipper bZIP transcription 0.0146 0.0404 0.0446
Schistosoma mansoni flap endonuclease-1 0.0097 0.0249 0.0276
Brugia malayi Nuclear hormone receptor family member nhr-25 0.0061 0.0133 0.0183
Brugia malayi Telomerase reverse transcriptase 0.2274 0.7229 1
Brugia malayi exodeoxyribonuclease III family protein 0.0057 0.0121 0.0167
Brugia malayi RNase H family protein 0.0113 0.0298 0.0412
Trichomonas vaginalis PIKK family atypical protein kinase 0.0026 0.0022 0.0064
Plasmodium vivax AP endonuclease (DNA-[apurinic or apyrimidinic site] lyase), putative 0.0057 0.0121 0.0445
Trypanosoma brucei phosphoglycerate kinase 0.0063 0.0138 0.0514
Brugia malayi isocitrate dehydrogenase 0.0031 0.0037 0.0051
Plasmodium falciparum conserved Plasmodium protein, unknown function 0.0025 0.0018 0.0068
Echinococcus granulosus calpain A 0.0021 0.0004 0.0002
Trichomonas vaginalis conserved hypothetical protein 0.0026 0.0022 0.0063
Trypanosoma brucei mitogen-activated protein kinase kinase 5 0.0082 0.02 0.0746
Echinococcus multilocularis tar DNA binding protein 0.0137 0.0376 0.0414
Plasmodium falciparum lysine-specific histone demethylase 1, putative 0.0025 0.0018 0.0068
Wolbachia endosymbiont of Brugia malayi exonuclease III 0.0057 0.0121 0.2472
Brugia malayi nuclear receptor RXR 0.0029 0.003 0.004
Echinococcus multilocularis BRK domain 0.0024 0.0014 0.0013
Mycobacterium ulcerans hypothetical protein 0.0049 0.0093 0.054
Trypanosoma brucei calpain-like cysteine peptidase, putative 0.011 0.029 0.108
Plasmodium falciparum importin beta, putative 0.0028 0.0029 0.0107
Toxoplasma gondii phosphofructokinase domain-containing protein 0.0029 0.003 0.0109
Trypanosoma brucei isocitrate dehydrogenase, putative 0.0031 0.0037 0.0137
Schistosoma mansoni disco-interacting protein 2 (dip2) 0.004 0.0066 0.0073
Onchocerca volvulus Serine\/threonine kinase homolog 0.0197 0.0568 0.0565
Echinococcus granulosus regulator of G protein signaling 7 0.0028 0.0028 0.0028
Trypanosoma cruzi Vps23 core domain containing protein, putative 0.0022 0.0009 0.0024
Trichomonas vaginalis PIKK family atypical protein kinase 0.0033 0.0043 0.0133
Toxoplasma gondii RNA-directed DNA polymerase 0.0855 0.2677 1
Brugia malayi regulator of G-protein signaling egl-10 0.0028 0.0028 0.0038
Giardia lamblia Pyrophosphate-fructose 6-phosphate 1-phosphotransferase alpha subunit 0.0029 0.003 0.008
Echinococcus multilocularis lysine specific histone demethylase 1A 0.0025 0.0018 0.0018
Loa Loa (eye worm) hypothetical protein 0.0032 0.0041 0.0134
Trichomonas vaginalis rotamase, putative 0.0033 0.0042 0.0131
Trichomonas vaginalis conserved hypothetical protein 0.0071 0.0166 0.0542
Loa Loa (eye worm) glutaminase 2 0.0544 0.1682 0.5877
Toxoplasma gondii ribonuclease HI protein 0.0113 0.0298 0.1112
Echinococcus granulosus bromodomain adjacent to zinc finger domain 0.0193 0.0558 0.0616
Trypanosoma brucei ribonuclease H1 0.0113 0.0298 0.1112
Echinococcus multilocularis SAM and MBT domain containing protein 0.0149 0.0416 0.0459
Loa Loa (eye worm) hypothetical protein 0.0025 0.0018 0.0056
Brugia malayi MAP kinase sur-1 0.0106 0.0279 0.0385
Loa Loa (eye worm) 6-phosphofructokinase 0.0107 0.0279 0.0969
Loa Loa (eye worm) BRM protein 0.0088 0.0219 0.076
Trypanosoma brucei protein kinase, putative 0.0106 0.0279 0.1039
Onchocerca volvulus 0.0081 0.0198 0.0196
Trypanosoma cruzi apurinic/apyrimidinic endonuclease, putative 0.0057 0.0121 0.0445
Brugia malayi MH1 domain containing protein 0.0025 0.0019 0.0025
Trypanosoma brucei ingi protein (ORF1) 0.0122 0.0329 0.1226
Trypanosoma cruzi PAB1-binding protein , putative 0.0052 0.0104 0.0378
Brugia malayi Protein cec-1. 0.0057 0.0121 0.0167
Echinococcus granulosus guanine nucleotide binding protein Gs subunit 0.0278 0.083 0.0918
Echinococcus granulosus importin subunit beta 1 0.0028 0.0029 0.0029
Trypanosoma cruzi ATP-dependent DEAD/H DNA helicase recQ, putative 0.0035 0.0051 0.0181
Echinococcus multilocularis histone lysine N methyltransferase, H3 lysine 36 0.0039 0.0064 0.0068
Toxoplasma gondii target of rapamycin (TOR), putative 0.0033 0.0043 0.0157
Loa Loa (eye worm) hypothetical protein 0.0146 0.0404 0.1406
Chlamydia trachomatis fructose-6-phosphate phosphotransferase 0.0029 0.003 0.0569
Brugia malayi photoreceptor-specific nuclear receptor 0.0061 0.0133 0.0183
Toxoplasma gondii 'chromo' (CHRromatin Organization MOdifier) domain-containing protein 0.0057 0.0121 0.0451
Trypanosoma cruzi phosphoglycerate kinase, putative 0.0171 0.0484 0.1801
Toxoplasma gondii ImpB/MucB/SamB family protein 0.0095 0.0242 0.0901
Schistosoma mansoni hepatocyte nuclear factor 4-alpha (hnf-4-alpha) 0.0029 0.003 0.0033
Echinococcus multilocularis histone lysine N methyltransferase NSD3 0.0107 0.0281 0.031
Schistosoma mansoni intermediate filament proteins 0.0081 0.0198 0.022
Giardia lamblia Kinase, STE STE20 0.0082 0.02 0.0578
Trypanosoma brucei calpain, putative 0.011 0.029 0.108
Trichomonas vaginalis PIKK family atypical protein kinase 0.0044 0.0079 0.0252
Giardia lamblia DNA damage repair protein 0.0042 0.0072 0.0204
Toxoplasma gondii XPG N-terminal domain-containing protein 0.0022 0.0007 0.0026
Brugia malayi nuclear hormone receptor 0.0029 0.003 0.004
Schistosoma mansoni calpain-7 (C02 family) 0.0021 0.0004 0.0004
Echinococcus multilocularis smad 0.0025 0.0019 0.0018
Schistosoma mansoni hypothetical protein 0.0097 0.0249 0.0276
Echinococcus granulosus nuclear receptor subfamily 4 group A 0.0029 0.003 0.003
Trichomonas vaginalis CAMK family protein kinase 0.0197 0.0568 0.1865
Schistosoma mansoni phosphoglycerate kinase 0.0171 0.0484 0.0537
Echinococcus granulosus nuclear receptor 2DBD gamma 0.0029 0.003 0.003
Toxoplasma gondii SWI2/SNF2 Brahma-like putative 0.0021 0.0006 0.0021
Loa Loa (eye worm) hypothetical protein 0.0057 0.0121 0.0416
Trypanosoma cruzi PAB1-binding protein , putative 0.0052 0.0104 0.0378
Trichomonas vaginalis phosphofructokinase, putative 0.0029 0.003 0.009
Echinococcus multilocularis mitogen activated protein kinase 3 0.0106 0.0279 0.0307
Trypanosoma brucei DNA damage repair protein, putative 0.0042 0.0072 0.0267
Loa Loa (eye worm) hypothetical protein 0.0029 0.003 0.0095
Leishmania major protein kinase, putative,polo-like protein kinase, putative 0.0197 0.0568 0.2108
Trypanosoma brucei apurinic/apyrimidinic endonuclease, putative 0.0057 0.0121 0.0452
Brugia malayi Nuclear hormone receptor-like 1 0.0032 0.0041 0.0055
Loa Loa (eye worm) hypothetical protein 0.0146 0.0404 0.1406
Schistosoma mansoni family C2 unassigned peptidase (C02 family) 0.0073 0.0172 0.0191
Echinococcus multilocularis PWWP domain containing protein 2A 0.0029 0.0031 0.0032
Echinococcus multilocularis BRK domain containing protein 0.0024 0.0014 0.0013
Entamoeba histolytica hypothetical protein 0.0146 0.0404 0.1181
Entamoeba histolytica hypothetical protein 0.0057 0.0121 0.0355
Schistosoma mansoni histone-lysine n-methyltransferase suv9 0.0184 0.0528 0.0586
Schistosoma mansoni hypothetical protein 0.0097 0.0249 0.0276
Echinococcus granulosus Smad4 0.0025 0.0019 0.0018
Plasmodium vivax importin-beta 2, putative 0.0028 0.0029 0.0099
Echinococcus granulosus zinc finger protein 0.007 0.0163 0.0178
Echinococcus multilocularis hepatoma derived growth factor protein 0.0029 0.0031 0.0032
Echinococcus granulosus tyrosyl DNA phosphodiesterase 1 0.0065 0.0146 0.0159
Loa Loa (eye worm) hypothetical protein 0.0069 0.016 0.055
Loa Loa (eye worm) hypothetical protein 0.0028 0.0029 0.0092
Loa Loa (eye worm) jmjC domain-containing protein 0.0085 0.0211 0.0731
Brugia malayi Bromodomain containing protein 0.0071 0.0166 0.0228
Echinococcus granulosus neuropeptide s receptor 0.0493 0.1518 0.1682
Echinococcus granulosus nuclear receptor 2DBD gamma 0.0061 0.0133 0.0145
Echinococcus granulosus histone lysine N methyltransferase MLL3 0.0044 0.0077 0.0083
Echinococcus multilocularis chromobox protein 2 0.0057 0.0121 0.0132
Echinococcus granulosus expressed protein 0.0366 0.1112 0.1231
Toxoplasma gondii hypothetical protein 0.0097 0.0248 0.0925
Chlamydia trachomatis fructose-6-phosphate phosphotransferase 0.0029 0.003 0.0569
Trichomonas vaginalis fructose-bisphosphate aldolase, putative 0.0604 0.1874 0.6178
Schistosoma mansoni Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) 0.0278 0.083 0.0921
Echinococcus multilocularis nuclear receptor subfamily 1 group D 0.0032 0.0041 0.0042
Echinococcus granulosus lysine specific demethylase 5A 0.0085 0.0211 0.0232
Brugia malayi Phosphatidylinositol 3- and 4-kinase family protein 0.0044 0.0079 0.0108
Leishmania major mitogen-activated protein kinase kinase 5, putative;with=GeneDB:LmxM36.0860 0.0082 0.02 0.0734
Schistosoma mansoni amine oxidase 0.0025 0.0018 0.002
Trichomonas vaginalis CAMK family protein kinase 0.0098 0.0252 0.0823
Brugia malayi hypothetical protein 0.0032 0.0041 0.0055
Echinococcus granulosus chromodomain helicase DNA binding protein 4 0.007 0.0161 0.0176
Trypanosoma cruzi ribonuclease H1, putative 0.0113 0.0298 0.1106
Echinococcus multilocularis Chromobox protein 3 0.0057 0.0121 0.0132
Entamoeba histolytica DNA-repair protein, putative 0.0022 0.0007 0.0022
Trichomonas vaginalis PIKK family atypical protein kinase 0.0024 0.0014 0.0037
Echinococcus granulosus Basic leucine zipper bZIP transcription factor 0.0181 0.0519 0.0573
Mycobacterium ulcerans fatty-acid-CoA ligase 0.0036 0.0054 0.0305
Echinococcus multilocularis nuclear receptor 2DBD gamma 0.0061 0.0133 0.0145
Leishmania major UDP-galactopyranose mutase 0.0025 0.0018 0.0054
Mycobacterium tuberculosis Probable flavin-containing monoamine oxidase AofH (amine oxidase) (MAO) 0.0333 0.1006 1
Plasmodium vivax DNA repair protein RAD2, putative 0.0022 0.0007 0.0019
Echinococcus granulosus retinoic acid receptor rxr beta a 0.0061 0.0133 0.0145
Echinococcus granulosus cytoplasmic intermediate filament protein 0.0039 0.0063 0.0068
Mycobacterium tuberculosis Probable fatty-acid-CoA ligase FadD35 (fatty-acid-CoA synthetase) (fatty-acid-CoA synthase) 0.0034 0.0047 0.0293
Schistosoma mansoni Lysine-specific histone demethylase 1 0.0025 0.0018 0.002
Echinococcus multilocularis regulator of G protein signaling 7 0.0028 0.0028 0.0028
Loa Loa (eye worm) nuclear hormone receptor family member nhr-1 0.0061 0.0133 0.0456
Trichomonas vaginalis PIKK family atypical protein kinase 0.0035 0.005 0.0157
Schistosoma mansoni lamin 0.0081 0.0198 0.022
Trichomonas vaginalis fructose-bisphosphate aldolase, putative 0.0604 0.1874 0.6178
Trichomonas vaginalis helicase, putative 0.0026 0.0022 0.0063
Leishmania major apurinic/apyrimidinic endonuclease-redox protein 0.0057 0.0121 0.044
Echinococcus granulosus replication factor c subunit 1 0.002 0.0002 0.00000019443
Brugia malayi hypothetical protein 0.0029 0.003 0.004
Schistosoma mansoni cpg binding protein 0.0161 0.0455 0.0505
Leishmania major ribonuclease H1, putative 0.0113 0.0298 0.11
Trypanosoma cruzi hypothetical protein, conserved 0.0022 0.0007 0.0019
Mycobacterium tuberculosis Conserved hypothetical protein 0.0317 0.0952 0.9456
Trichomonas vaginalis phosphofructokinase, putative 0.0107 0.0279 0.0914
Echinococcus multilocularis global transcription activator snf2l2 0.0145 0.0402 0.0444
Schistosoma mansoni mixed-lineage leukemia protein mll 0.0254 0.0751 0.0833
Schistosoma mansoni family C2 unassigned peptidase (C02 family) 0.0073 0.0172 0.0191
Brugia malayi Nuclear hormone receptor family member nhr-25 0.0061 0.0133 0.0183
Echinococcus multilocularis histone acetyltransferase MYST2 0.017 0.0482 0.0533
Mycobacterium leprae Probable fructose bisphosphate aldolase Fba 0.0295 0.0883 1
Echinococcus multilocularis histone lysine N methyltransferase MLL3 0.0037 0.0055 0.0058
Echinococcus multilocularis calpain A 0.0073 0.0172 0.0189
Echinococcus multilocularis terminal deoxycytidyl transferase rev1 0.0135 0.0371 0.0409
Echinococcus granulosus neuropeptide receptor A26 0.0493 0.1518 0.1682
Loa Loa (eye worm) nuclear receptor NHR-67 0.0029 0.003 0.0095
Leishmania major DNA damage repair protein, putative 0.0042 0.0072 0.0255
Brugia malayi calcium-independent alpha-latrotoxin receptor 2, putative 0.0097 0.0249 0.0344
Trypanosoma brucei importin beta-1 subunit, putative 0.0028 0.0029 0.0105
Trichomonas vaginalis CAMK family protein kinase 0.0197 0.0568 0.1865
Loa Loa (eye worm) runx1 0.0059 0.0127 0.0435
Trypanosoma brucei cysteine peptidase, Clan CA, family C2, putative 0.0021 0.0004 0.0013
Loa Loa (eye worm) hypothetical protein 0.0911 0.286 1
Trichomonas vaginalis myo inositol monophosphatase, putative 0.004 0.0066 0.0209
Trypanosoma brucei DNA polymerase kappa, putative 0.0164 0.0463 0.1727
Loa Loa (eye worm) hypothetical protein 0.0025 0.0018 0.0056
Treponema pallidum exodeoxyribonuclease (exoA) 0.0057 0.0121 0.0636
Echinococcus granulosus geminin 0.0334 0.1008 0.1116
Loa Loa (eye worm) hypothetical protein 0.0025 0.0018 0.0056
Echinococcus granulosus PHD finger protein rhinoceros 0.006 0.0131 0.0142
Schistosoma mansoni hypothetical protein 0.0081 0.0198 0.0219
Trypanosoma cruzi calpain-like cysteine peptidase, putative 0.0021 0.0004 0.0006
Brugia malayi TAR-binding protein 0.0137 0.0376 0.0519
Schistosoma mansoni chromobox protein 0.0293 0.0878 0.0974
Schistosoma mansoni hypothetical protein 0.0029 0.0031 0.0034
Trichomonas vaginalis importin beta-1, putative 0.0023 0.0011 0.003
Leishmania major hypothetical protein, conserved 0.0047 0.0088 0.0314
Mycobacterium ulcerans acyl-CoA synthetase 0.0049 0.0093 0.054
Mycobacterium ulcerans acyl-CoA synthetase 0.0049 0.0093 0.054
Giardia lamblia DNA repair protein RAD52 0.1087 0.3422 1
Trypanosoma cruzi DNA polymerase beta thumb, putative 0.0085 0.0208 0.077
Trichomonas vaginalis STE family protein kinase 0.0082 0.02 0.0653
Onchocerca volvulus Ribonuclease H1 homolog 0.0113 0.0298 0.0296
Schistosoma mansoni cpg binding protein 0.0161 0.0455 0.0505
Plasmodium falciparum conserved Plasmodium protein, unknown function 0.0057 0.0121 0.0453
Toxoplasma gondii ATP-dependent DNA helicase, RecQ family protein 0.0069 0.016 0.0594
Brugia malayi hypothetical protein 0.0029 0.0031 0.0042
Loa Loa (eye worm) hypothetical protein 0.0471 0.1447 0.5057
Entamoeba histolytica exonuclease, putative 0.0022 0.0007 0.0022
Echinococcus multilocularis serine:threonine protein kinase PLK1 0.0197 0.0568 0.0627
Toxoplasma gondii ATPase, AAA family protein 0.002 0.0002 0.0007
Trichomonas vaginalis chromodomain helicase DNA binding protein, putative 0.0084 0.0206 0.0671
Trypanosoma cruzi mitogen-activated protein kinase kinase 5 0.0082 0.02 0.0739
Schistosoma mansoni tsg101-related 0.0058 0.0123 0.0137
Onchocerca volvulus Polycomb protein Sfmbt homolog 0.0149 0.0416 0.0414
Leishmania major mitogen activated protein kinase 4, putative;with=GeneDB:LmxM19.1440 0.0106 0.0279 0.1028
Loa Loa (eye worm) hypothetical protein 0.0087 0.0215 0.0745
Trichomonas vaginalis chromobox protein, putative 0.0293 0.0878 0.289
Echinococcus granulosus Nuclear hormone receptor HR96 0.0029 0.003 0.003
Loa Loa (eye worm) isocitrate dehydrogenase 0.0031 0.0037 0.0122
Trichomonas vaginalis chromodomain helicase DNA binding protein, putative 0.0084 0.0206 0.0671
Trichomonas vaginalis Heterochromatin protein, putative 0.0057 0.0121 0.0393
Loa Loa (eye worm) hypothetical protein 0.0049 0.0093 0.0317
Trypanosoma cruzi DNA repair protein RAD2, putative 0.0022 0.0007 0.0019
Schistosoma mansoni chromobox protein-related (chromobox 1) (heterochromatin 1) 0.0057 0.0121 0.0135
Loa Loa (eye worm) hypothetical protein 0.0911 0.286 1
Trypanosoma cruzi calpain-like cysteine peptidase, putative 0.011 0.029 0.1074
Schistosoma mansoni bromodomain containing protein 0.0204 0.0593 0.0658
Plasmodium vivax hypothetical protein, conserved 0.0025 0.0018 0.006
Echinococcus granulosus nuclear receptor subfamily 1 group D 0.0032 0.0041 0.0042
Trypanosoma brucei DNA polymerase kappa, putative 0.0164 0.0463 0.1727
Loa Loa (eye worm) hypothetical protein 0.0029 0.003 0.0095
Echinococcus granulosus DNA apurinic or apyrimidinic site lyase 0.0057 0.0121 0.0132
Schistosoma mansoni nuclear receptor 2DBD-gamma 0.0061 0.0133 0.0147
Trypanosoma brucei transcription elongation factor s-II, putative 0.0029 0.0031 0.0113
Loa Loa (eye worm) hypothetical protein 0.0061 0.0133 0.0456
Schistosoma mansoni blooms syndrome DNA helicase 0.0103 0.0266 0.0296
Trypanosoma cruzi flap endonuclease-1 (FEN-1), putative 0.0108 0.0282 0.1046
Plasmodium falciparum phd finger protein, putative 0.006 0.0131 0.0488
Echinococcus multilocularis calpain family protein 1, d 0.0049 0.0094 0.0102
Echinococcus multilocularis geminin 0.0334 0.1008 0.1116
Trichomonas vaginalis conserved hypothetical protein 0.0026 0.0022 0.0063
Brugia malayi AMP-binding enzyme family protein 0.0049 0.0093 0.0128
Toxoplasma gondii 6-phosphofructokinase 0.0029 0.003 0.0109
Chlamydia trachomatis protoporphyrinogen oxidase 0.0025 0.0018 0.0332
Schistosoma mansoni glutaminase 0.0544 0.1682 0.1866
Trichomonas vaginalis Importin beta-1 subunit, putative 0.0023 0.0011 0.003
Loa Loa (eye worm) helicase 0.0057 0.0121 0.0416
Onchocerca volvulus 0.0965 0.3032 0.3031
Schistosoma mansoni hypothetical protein 0.0304 0.0913 0.1013
Trypanosoma cruzi cysteine peptidase, Clan CA, family C2, putative 0.0021 0.0004 0.0006
Echinococcus multilocularis suppression of tumorigenicity 18 protein 0.017 0.0482 0.0533

Activities

Activity type Activity value Assay description Source Reference
A-selectivity (binding) = 5200 Selectivity for rat Monoamine oxidase A as ratio of Ki(MAO-B)/Ki(MAO-A) ChEMBL. 15974574
Ki (binding) = 2 Inhibition of MAO-A receptor ChEMBL. 21397504
Ki (binding) = 0.01 uM Inhibtory concentration for rat Monoamine oxidase A ChEMBL. 15974574
Ki (binding) = 0.01 uM Inhibtory concentration for rat Monoamine oxidase A ChEMBL. 15974574
Ki (binding) = 520 uM Inhibitory concentration for human Monoamine oxidase B ChEMBL. 15974574
Ki (binding) = 520 uM Inhibitory concentration for human Monoamine oxidase B ChEMBL. 15974574

Phenotypes

Whole-cell/tissue/organism interactions

We have no records of whole-cell/tissue assays done with this compound What does this mean?

Many chemical entities in TDR Targets come from high-throughput screenings with whole cells or tissue samples, and not all assayed compounds have been tested against a single a single target protein, probably because they get ruled out during screening process. Even if these compounds may have not been of interest in the original screening, they may come as interesting leads for other screening assays. Furthermore, we may be able to propose drug-target associations using chemical similarities and network patterns.

Annotated phenotypes:

We have no manually annotated phenotypes for this drug. What does this mean? / Care to help?
In TDR Targets, information about phenotypes that are caused by drugs, or by genetic manipulation of cells (e.g. gene knockouts or knockdowns) is manually curated from the literature. These descriptions help to describe the potential of the target for drug development. If no information is available for this gene or if the information is incomplete, this may mean that i) the papers containing this information either appeared after the curation effort for this organism was carried out or they were inadvertently missed by curators; or that ii) the curation effort for this organism has not yet started.
 
In any case, if you have information about papers containing relevant validation data for this target, please log in using your TDR Targets username and password and send them to us using the corresponding form in this page (only visible to registered users) or contact us.

External resources for this compound

Bibliographic References

2 literature references were collected for this gene.

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