Detailed information for compound 376487

Basic information

Technical information
  • Name: Unnamed compound
  • MW: 2836.98 | Formula: C123H182N36O42
  • H donors: 45 H acceptors: 43 LogP: -17.97 Rotable bonds: 116
    Rule of 5 violations (Lipinski): 4
  • SMILES: NCCCC[C@@H](C(=O)N[C@H](C(=O)N[C@H](C(=O)N[C@H](C(=O)N[C@H](C(=O)N[C@H](C(=O)N[C@H](C(=O)N[C@H](C(=O)N[C@H](C(=O)N[C@H](C(=O)N[C@H](C(=O)N[C@H](C(=O)N[C@H](C(=O)O)CCC(=O)N)C(C)C)Cc1ccccc1)CC(=O)O)CCC(=O)N)C)CCCN=C(N)N)CCCN=C(N)N)CO)CC(=O)O)CC(C)C)Cc1ccc(cc1)O)NC(=O)[C@@H](NC(=O)[C@@H](NC(=O)[C@@H](NC(=O)[C@@H](NC(=O)[C@H]([C@H](O)C)NC(=O)[C@@H](NC(=O)[C@H]([C@H](O)C)NC(=O)CNC(=O)[C@@H](NC(=O)[C@@H](NC(=O)[C@H](Cc1nc[nH]c1)N)CO)CCC(=O)N)Cc1ccccc1)CO)CC(=O)O)Cc1ccc(cc1)O)CO
  • InChi: 1S/C123H182N36O42/c1-58(2)42-77(106(185)150-84(50-95(176)177)111(190)155-87(55-162)116(195)142-73(24-17-41-135-123(131)132)103(182)140-72(23-16-40-134-122(129)130)102(181)138-60(5)99(178)139-75(34-37-90(127)169)105(184)149-82(48-93(172)173)109(188)148-80(43-63-18-10-8-11-19-63)112(191)158-96(59(3)4)118(197)144-76(121(200)201)35-38-91(128)170)145-107(186)78(45-65-25-29-68(166)30-26-65)146-104(183)71(22-14-15-39-124)141-115(194)86(54-161)154-108(187)79(46-66-27-31-69(167)32-28-66)147-110(189)83(49-94(174)175)151-117(196)88(56-163)156-120(199)98(62(7)165)159-113(192)81(44-64-20-12-9-13-21-64)152-119(198)97(61(6)164)157-92(171)52-136-101(180)74(33-36-89(126)168)143-114(193)85(53-160)153-100(179)70(125)47-67-51-133-57-137-67/h8-13,18-21,25-32,51,57-62,70-88,96-98,160-167H,14-17,22-24,33-50,52-56,124-125H2,1-7H3,(H2,126,168)(H2,127,169)(H2,128,170)(H,133,137)(H,136,180)(H,138,181)(H,139,178)(H,140,182)(H,141,194)(H,142,195)(H,143,193)(H,144,197)(H,145,186)(H,146,183)(H,147,189)(H,148,188)(H,149,184)(H,150,185)(H,151,196)(H,152,198)(H,153,179)(H,154,187)(H,155,190)(H,156,199)(H,157,171)(H,158,191)(H,159,192)(H,172,173)(H,174,175)(H,176,177)(H,200,201)(H4,129,130,134)(H4,131,132,135)/t60-,61+,62+,70-,71-,72-,73-,74-,75-,76-,77-,78-,79-,80-,81-,82-,83-,84-,85-,86-,87-,88-,96-,97-,98-/m0/s1
  • InChiKey: AMNXVVDVLJQQDQ-HXJWOVOWSA-N  


Substructure search Similarity search

Network

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Synonyms

No synonyms found for this compound

Targets

Known targets for this compound

No curated genes were found associated with this compound

Predicted pathogen targets for this compound

By orthology
No druggable targets predicted by orthology data
By sequence similarity to non orthologous known druggable targets
No druggable targets predicted by sequence similarity
Obtained from network model

Ranking Plot

Putative Targets List

Species Potential target Raw Global Species
Echinococcus granulosus dual 3'5' cyclic AMP and GMP phosphodiesterase 0.0184 0.1023 0.1207
Brugia malayi hypothetical protein 0.0071 0.0344 0.0405
Echinococcus multilocularis high affinity cgmp specific 3' 5' cyclic 0.0074 0.036 0.0358
Mycobacterium leprae Probable fructose bisphosphate aldolase Fba 0.015 0.0823 1
Echinococcus granulosus tachykinin peptides receptor 99D 0.07 0.4137 0.4893
Schistosoma mansoni NADP-specific isocitrate dehydrogenase 0.0017 0.0016 0.0017
Loa Loa (eye worm) hypothetical protein 0.07 0.4137 0.4893
Echinococcus granulosus mitogen activated protein kinase 3 0.0102 0.0531 0.0626
Trichomonas vaginalis conserved hypothetical protein 0.0049 0.0207 0.0256
Loa Loa (eye worm) hypothetical protein 0.07 0.4137 0.4893
Mycobacterium tuberculosis Possible DNA-damage-inducible protein P DinP (DNA polymerase V) (pol IV 2) (DNA nucleotidyltransferase (DNA-directed)) 0.0046 0.0193 0.1217
Loa Loa (eye worm) hypothetical protein 0.07 0.4137 0.4893
Trichomonas vaginalis phosphofructokinase, putative 0.003 0.0093 0.0102
Brugia malayi Serotonin/octopamine receptor family protein 7 0.07 0.4137 0.4893
Echinococcus granulosus sodium and chloride dependent glycine 0.0029 0.0087 0.0101
Trypanosoma cruzi JmjC domain, hydroxylase, putative 0.0016 0.0011 0.0035
Echinococcus multilocularis sex peptide receptor 0.07 0.4137 0.4136
Echinococcus granulosus uncharacterized sodium dependent transporter 0.0029 0.0087 0.0101
Echinococcus multilocularis thyrotropin releasing hormone receptor 0.07 0.4137 0.4136
Echinococcus granulosus sodium and chloride dependent glycine 0.0029 0.0087 0.0101
Schistosoma mansoni hypothetical protein 0.0016 0.001 0.0009
Schistosoma mansoni amine GPCR 0.07 0.4137 0.4893
Echinococcus granulosus o acyltransferase membrane bound domain 0.0049 0.0207 0.0243
Giardia lamblia Pyrophosphate-fructose 6-phosphate 1-phosphotransferase alpha subunit 0.003 0.0093 0.0213
Schistosoma mansoni histone-lysine n-methyltransferase setb1 0.0157 0.0861 0.1016
Plasmodium vivax SET domain protein, putative 0.0157 0.0861 0.3371
Trichomonas vaginalis cGMP-specific 3,5-cyclic phosphodiesterase, putative 0.0184 0.1023 0.1357
Schistosoma mansoni histone-lysine n-methyltransferase setb1 0.0157 0.0861 0.1016
Echinococcus granulosus lamin 0.0056 0.0254 0.0298
Echinococcus granulosus beta LACTamase domain containing family member 0.004 0.0158 0.0185
Toxoplasma gondii hypothetical protein 0.0049 0.0207 0.0772
Plasmodium vivax amine transporter, putative 0.0029 0.0087 0.0341
Trypanosoma brucei DNA polymerase IV, putative 0.0062 0.0291 0.1101
Loa Loa (eye worm) hypothetical protein 0.07 0.4137 0.4893
Schistosoma mansoni 6-phosphofructokinase 0.011 0.0577 0.068
Echinococcus granulosus biogenic amine 5HT receptor 0.07 0.4137 0.4893
Echinococcus multilocularis o acyltransferase (membrane bound) domain 0.0049 0.0207 0.0205
Schistosoma mansoni camp/cgmp cyclic nucleotide phosphodiesterase 0.0184 0.1023 0.1207
Brugia malayi cytoplasmic intermediate filament protein 0.003 0.0096 0.0112
Echinococcus granulosus terminal deoxycytidyl transferase rev1 0.0038 0.0145 0.017
Brugia malayi Isocitrate dehydrogenase 0.0017 0.0016 0.0017
Brugia malayi neuropeptide F receptor 0.07 0.4137 0.4893
Echinococcus granulosus dro:myosuppressin receptor 0.07 0.4137 0.4893
Onchocerca volvulus 0.0056 0.0254 0.034
Echinococcus multilocularis sterol O acyltransferase 1 0.0497 0.2915 0.2914
Schistosoma mansoni rhodopsin-like orphan GPCR 0.07 0.4137 0.4893
Echinococcus multilocularis histone lysine N methyltransferase SETMAR 0.0157 0.0861 0.0859
Echinococcus granulosus Ankyrin 0.0015 0.0003 0.0001
Leishmania major glycerol uptake protein, putative 0.0049 0.0207 0.0805
Brugia malayi Hhat protein 0.0049 0.0207 0.0243
Loa Loa (eye worm) isocitrate dehydrogenase 0.0017 0.0016 0.0017
Schistosoma mansoni amine GPCR 0.07 0.4137 0.4893
Echinococcus multilocularis inositol monophosphatase 1 0.0037 0.0136 0.0134
Trichomonas vaginalis conserved hypothetical protein 0.0074 0.036 0.0462
Echinococcus granulosus lipoxygenase domain containing protein 0.002 0.0033 0.0037
Trichomonas vaginalis fructose-bisphosphate aldolase, putative 0.0308 0.1774 0.2371
Loa Loa (eye worm) CMGC/MAPK/ERK1 protein kinase 0.0102 0.0531 0.0626
Trypanosoma brucei mitochondrial DNA polymerase beta 0.0323 0.1862 0.7282
Onchocerca volvulus 0.004 0.0158 0.0211
Echinococcus multilocularis rhodopsin orphan GPCR 0.07 0.4137 0.4136
Echinococcus granulosus Membrane bound O acyl transferase MBOAT 0.0049 0.0207 0.0243
Echinococcus multilocularis NADP dependent isocitrate dehydrogenase 0.0017 0.0016 0.0014
Trypanosoma cruzi mitochondrial DNA polymerase beta-PAK, putative 0.0153 0.0836 0.327
Brugia malayi isocitrate dehydrogenase 0.0017 0.0016 0.0017
Schistosoma mansoni jumonji domain containing protein 0.0016 0.0011 0.0011
Treponema pallidum fructose-bisphosphate aldolase 0.0308 0.1774 1
Loa Loa (eye worm) hypothetical protein 0.0074 0.036 0.0424
Trypanosoma brucei cAMP-specific phosphodiesterase, putative 0.0074 0.036 0.1372
Trypanosoma cruzi cytochrome P450, putative 0.0046 0.0193 0.0747
Treponema pallidum diphosphate--fructose-6-phosphate 1-phosphotransferase 0.011 0.0577 0.2879
Echinococcus multilocularis neuropeptide FF receptor 2 0.07 0.4137 0.4136
Trichomonas vaginalis high-affinity cGMP-specific 3,5-cyclic phosphodiesterase, putative 0.0184 0.1023 0.1357
Leishmania major mitochondrial DNA polymerase beta-PAK, putative 0.0153 0.0836 0.327
Loa Loa (eye worm) hypothetical protein 0.07 0.4137 0.4893
Plasmodium vivax hypothetical protein, conserved 0.0029 0.0087 0.0341
Loa Loa (eye worm) hypothetical protein 0.07 0.4137 0.4893
Echinococcus multilocularis 6 phosphofructokinase 0.011 0.0577 0.0575
Echinococcus multilocularis sodium dependent neurotransmitter transporter 0.0029 0.0087 0.0085
Mycobacterium ulcerans aldehyde dehydrogenase 0.0122 0.0653 0.6637
Echinococcus granulosus bloom syndrome protein 0.0021 0.0041 0.0046
Mycobacterium tuberculosis Conserved hypothetical protein 0.0038 0.0145 0.0886
Schistosoma mansoni neuropeptide receptor 0.07 0.4137 0.4893
Echinococcus multilocularis lamin 0.0056 0.0254 0.0252
Schistosoma mansoni ankyrin 23/unc44 0.0015 0.0002 0.000000052905
Brugia malayi GTP-binding nuclear protein RAN/TC4 0.0024 0.0057 0.0065
Wolbachia endosymbiont of Brugia malayi fructose-1,6-bisphosphatase 0.0037 0.0136 0.5
Mycobacterium tuberculosis Probable cytochrome P450 128 Cyp128 0.0028 0.0086 0.0478
Brugia malayi Cytochrome P450 family protein 0.0046 0.0193 0.0226
Loa Loa (eye worm) hypothetical protein 0.0497 0.2915 0.3447
Entamoeba histolytica myo-inositol monophosphatase, putative 0.0037 0.0136 0.0462
Loa Loa (eye worm) hypothetical protein 0.07 0.4137 0.4893
Loa Loa (eye worm) Sodium:neurotransmitter symporter family protein 0.0029 0.0087 0.0101
Echinococcus multilocularis sodium and chloride dependent glycine 0.0029 0.0087 0.0085
Brugia malayi hypothetical protein 0.07 0.4137 0.4893
Trichomonas vaginalis conserved hypothetical protein 0.011 0.0577 0.0755
Trypanosoma brucei DNA polymerase kappa, putative 0.007 0.0339 0.1291
Loa Loa (eye worm) beta-LACTamase domain containing family member 0.004 0.0158 0.0185
Loa Loa (eye worm) hypothetical protein 0.0029 0.0087 0.0101
Onchocerca volvulus 0.07 0.4137 0.5572
Echinococcus multilocularis ankyrin repeat and death domain containing protein 0.0015 0.0002 0.000000044724
Echinococcus granulosus lysophospholipid acyltransferase 7 0.0049 0.0207 0.0243
Echinococcus multilocularis somatostatin receptor 0.07 0.4137 0.4136
Trypanosoma cruzi PAB1-binding protein , putative 0.0053 0.0231 0.0899
Onchocerca volvulus Neuropeptide F receptor homolog 0.07 0.4137 0.5572
Echinococcus multilocularis cAMP and cAMP inhibited cGMP 3',5' cyclic 0.0114 0.0601 0.0599
Trypanosoma cruzi hypothetical protein, conserved 0.0074 0.036 0.1403
Plasmodium falciparum ADP-dependent DNA helicase RecQ 0.0018 0.0026 0.0373
Brugia malayi beta-lactamase family protein 0.004 0.0158 0.0185
Schistosoma mansoni hypothetical protein 0.0049 0.0208 0.0244
Giardia lamblia Fructose-bisphosphate aldolase 0.0308 0.1774 1
Mycobacterium leprae PROBABLE 6-PHOSPHOFRUCTOKINASE PFKA (PHOSPHOHEXOKINASE) (PHOSPHOFRUCTOKINASE) 0.011 0.0577 0.6668
Entamoeba histolytica membrane-bound O-acyltransferase (MBOAT ) family protein 0.0049 0.0207 0.0877
Echinococcus multilocularis GTP binding nuclear protein Ran 0.0024 0.0057 0.0055
Trichomonas vaginalis calcium/calmodulin-dependent 3,5-cyclic nucleotide phosphodiesterase, putative 0.0184 0.1023 0.1357
Echinococcus granulosus neuropeptide receptor 0.07 0.4137 0.4893
Mycobacterium ulcerans fructose-bisphosphate aldolase 0.015 0.0823 0.8622
Trypanosoma cruzi cAMP phosphodiesterase A, putative 0.0437 0.2553 1
Toxoplasma gondii ABC1 family protein 0.004 0.0158 0.0579
Schistosoma mansoni sodium/chloride dependent neurotransmitter transporter 0.0029 0.0087 0.0101
Loa Loa (eye worm) hhat protein 0.0049 0.0207 0.0243
Trichomonas vaginalis phosphofructokinase, putative 0.011 0.0577 0.0755
Trypanosoma brucei DNA polymerase kappa, putative 0.0034 0.0122 0.0435
Echinococcus multilocularis allatostatin A receptor 0.07 0.4137 0.4136
Trypanosoma cruzi DNA polymerase kappa, putative 0.007 0.0339 0.1322
Schistosoma mansoni rab geranylgeranyl transferase alpha subunit 0.0038 0.0145 0.017
Loa Loa (eye worm) hypothetical protein 0.0038 0.0145 0.017
Echinococcus granulosus g protein coupled receptor 0.07 0.4137 0.4893
Echinococcus multilocularis uncharacterized sodium dependent transporter 0.0029 0.0087 0.0085
Echinococcus multilocularis tm gpcr rhodopsin gpcr rhodopsin superfamily 0.07 0.4137 0.4136
Mycobacterium ulcerans DNA polymerase IV 0.007 0.0339 0.2965
Brugia malayi ORL1-like opioid receptor 0.07 0.4137 0.4893
Trypanosoma brucei DNA polymerase kappa, putative 0.007 0.0339 0.1291
Mycobacterium tuberculosis Probable cytochrome P450 138 Cyp138 0.0028 0.0086 0.0478
Entamoeba histolytica pyrophosphate-dependent phosphofructokinase 0.003 0.0093 0.0213
Echinococcus multilocularis neuropeptide receptor 0.07 0.4137 0.4136
Echinococcus multilocularis lysine specific demethylase 6a 0.0016 0.0011 0.0009
Brugia malayi Uncoordinated protein 44 0.0015 0.0002 0.000000052905
Schistosoma mansoni ran 0.0024 0.0057 0.0065
Schistosoma mansoni leukocyte receptor cluster (lrc) member 4 protein 0.0049 0.0207 0.0243
Echinococcus granulosus dna polymerase kappa 0.007 0.0339 0.0399
Schistosoma mansoni camp-specific 35-cyclic phosphodiesterase 0.0074 0.036 0.0424
Trichomonas vaginalis fructose-bisphosphate aldolase, putative 0.0308 0.1774 0.2371
Brugia malayi hypothetical protein 0.07 0.4137 0.4893
Trichomonas vaginalis D-aminoacylase, putative 0.004 0.0158 0.019
Trichomonas vaginalis D-aminoacylase, putative 0.004 0.0158 0.019
Trichomonas vaginalis Importin beta-1 subunit, putative 0.0026 0.0071 0.0072
Leishmania major isocitrate dehydrogenase [NADP], mitochondrial precursor, putative 0.0017 0.0016 0.0055
Schistosoma mansoni gcn5proteinral control of amino-acid synthesis 5-like 2 gcnl2 0.0297 0.171 0.2021
Onchocerca volvulus 0.07 0.4137 0.5572
Trichomonas vaginalis conserved hypothetical protein 0.0184 0.1023 0.1357
Mycobacterium ulcerans extragenic suppressor protein SuhB 0.0037 0.0136 0.0588
Schistosoma mansoni opsin-like receptor 0.07 0.4137 0.4893
Schistosoma mansoni adenoreceptor 0.07 0.4137 0.4893
Plasmodium falciparum phosphodiesterase delta, putative 0.0074 0.036 0.9008
Echinococcus granulosus cAMP specific 3'5' cyclic phosphodiesterase 0.0074 0.036 0.0424
Trichomonas vaginalis CMGC family protein kinase 0.0102 0.0531 0.0693
Plasmodium falciparum cGMP-specific phosphodiesterase 0.0074 0.036 0.9008
Mycobacterium tuberculosis Probable cytochrome P450 141 Cyp141 0.0028 0.0086 0.0478
Trypanosoma cruzi cAMP phosphodiesterase A, putative 0.0437 0.2553 1
Onchocerca volvulus 0.0049 0.0208 0.0278
Schistosoma mansoni jumonji/arid domain-containing protein 0.006 0.0277 0.0326
Schistosoma mansoni sterol O-acyltransferase 1 0.0497 0.2915 0.3447
Echinococcus multilocularis sodium and chloride dependent glycine 0.0029 0.0087 0.0085
Brugia malayi larval opioid receptor 0.07 0.4137 0.4893
Echinococcus multilocularis isocitrate dehydrogenase 0.0017 0.0016 0.0014
Trichomonas vaginalis penicillin-binding protein, putative 0.004 0.0158 0.019
Trypanosoma brucei cAMP-specific phosphodiesterase 0.0184 0.1023 0.3979
Onchocerca volvulus 0.0083 0.0416 0.0558
Loa Loa (eye worm) 5-hydroxytryptamine 2C receptor 0.07 0.4137 0.4893
Trypanosoma brucei hypothetical protein, conserved 0.0074 0.036 0.1372
Schistosoma mansoni blooms syndrome DNA helicase 0.0017 0.0014 0.0015
Leishmania major DNA polymerase kappa, putative,DNA polymerase IV, putative 0.0046 0.0193 0.075
Trypanosoma cruzi cAMP specific phosphodiesterase, putative 0.0184 0.1023 0.4
Mycobacterium ulcerans 6-phosphofructokinase 0.011 0.0577 0.5749
Trypanosoma brucei importin beta-1 subunit, putative 0.0032 0.0108 0.0381
Echinococcus multilocularis fmrfamide receptor 0.07 0.4137 0.4136
Schistosoma mansoni muscarinic acetylcholine (GAR) receptor 0.07 0.4137 0.4893
Schistosoma mansoni membrane-bound acyltransferase/hhat 0.0049 0.0207 0.0243
Loa Loa (eye worm) G-protein-linked acetylcholine receptor protein 2 0.07 0.4137 0.4893
Loa Loa (eye worm) TYRA-2 protein 0.07 0.4137 0.4893
Trypanosoma brucei unspecified product 0.0062 0.0291 0.1101
Trichomonas vaginalis myo inositol monophosphatase, putative 0.0037 0.0136 0.016
Brugia malayi diacylglycerol acyltransferase 0.0049 0.0207 0.0243
Trypanosoma cruzi GUP1, putative 0.0049 0.0207 0.0805
Echinococcus granulosus GTP binding nuclear protein Ran 0.0024 0.0057 0.0065
Schistosoma mansoni rab6-interacting 0.002 0.0033 0.0037
Schistosoma mansoni rhodopsin-like orphan GPCR 0.07 0.4137 0.4893
Toxoplasma gondii 3'5'-cyclic nucleotide phosphodiesterase domain-containing protein 0.0074 0.036 0.1372
Echinococcus multilocularis geminin 0.0349 0.2022 0.202
Loa Loa (eye worm) hypothetical protein 0.07 0.4137 0.4893
Echinococcus multilocularis dna polymerase kappa 0.007 0.0339 0.0337
Leishmania major glycerol uptake protein, putative 0.0049 0.0207 0.0805
Trichomonas vaginalis cyclic nucleotide phosphodiesterase, putative 0.0184 0.1023 0.1357
Mycobacterium tuberculosis Possible cytochrome P450 135B1 Cyp135B1 0.0028 0.0086 0.0478
Schistosoma mansoni amine GPCR 0.07 0.4137 0.4893
Schistosoma mansoni aldehyde dehydrogenase 0.0122 0.0653 0.077
Trypanosoma brucei DNA polymerase kappa, putative 0.0034 0.0122 0.0435
Schistosoma mansoni jumonji domain containing protein 0.006 0.0277 0.0326
Echinococcus granulosus g protein coupled receptor 0.07 0.4137 0.4893
Schistosoma mansoni ran 0.0024 0.0057 0.0065
Entamoeba histolytica hypothetical protein 0.0049 0.0207 0.0877
Echinococcus granulosus g protein coupled receptor 0.07 0.4137 0.4893
Echinococcus multilocularis NADP dependent isocitrate dehydrogenase 0.0017 0.0016 0.0014
Schistosoma mansoni growth hormone secretagogue receptor 0.07 0.4137 0.4893
Brugia malayi Iron-sulfur cluster assembly accessory protein 0.0049 0.0208 0.0244
Trypanosoma cruzi glycerol uptake protein, putative 0.0049 0.0207 0.0805
Trypanosoma cruzi glycerol uptake protein, putative 0.0049 0.0207 0.0805
Echinococcus granulosus neuropeptide FF receptor 2 0.07 0.4137 0.4893
Echinococcus granulosus cytochrome P450 2K1 0.0028 0.0086 0.0099
Schistosoma mansoni zinc finger protein 0.0049 0.0207 0.0243
Mycobacterium tuberculosis Probable 6-phosphofructokinase PfkA (phosphohexokinase) (phosphofructokinase) 0.011 0.0577 0.3851
Toxoplasma gondii 3'5'-cyclic nucleotide phosphodiesterase domain-containing protein 0.0074 0.036 0.1372
Mycobacterium ulcerans cytochrome P450 185A4 Cyp185A4 0.0046 0.0193 0.1251
Trichomonas vaginalis cAMP-specific phosphodiesterase, putative 0.0144 0.0782 0.1032
Trichomonas vaginalis CMGC family protein kinase 0.0102 0.0531 0.0693
Echinococcus granulosus histone acetyltransferase KAT2B 0.0087 0.0442 0.0521
Onchocerca volvulus 0.002 0.0033 0.0042
Brugia malayi hypothetical protein 0.0034 0.0119 0.0139
Trichomonas vaginalis phosphofructokinase, putative 0.003 0.0093 0.0102
Schistosoma mansoni sodium-dependent neurotransmitter transporter 0.0029 0.0087 0.0101
Echinococcus multilocularis lipoxygenase domain containing protein 0.002 0.0033 0.0031
Loa Loa (eye worm) hypothetical protein 0.0049 0.0207 0.0243
Schistosoma mansoni high-affinity cgmp-specific 35-cyclic phosphodiesterase 0.0074 0.036 0.0424
Loa Loa (eye worm) hypothetical protein 0.004 0.0158 0.0185
Brugia malayi Unidentified vitellogenin-linked transcript protein 6, putative 0.07 0.4137 0.4893
Loa Loa (eye worm) hypothetical protein 0.07 0.4137 0.4893
Brugia malayi 6-phosphofructokinase 0.011 0.0577 0.068
Trypanosoma cruzi GUP1, putative 0.0049 0.0207 0.0805
Trypanosoma brucei DNA polymerase kappa, putative 0.007 0.0339 0.1291
Echinococcus granulosus lysine specific demethylase 6a 0.0016 0.0011 0.0011
Echinococcus granulosus jumonji domain containing 1A 0.0016 0.0011 0.0011
Echinococcus multilocularis G protein coupled 5 hydroxytryptamine receptor 0.07 0.4137 0.4136
Toxoplasma gondii isocitrate dehydrogenase 0.0017 0.0016 0.002
Leishmania major hypothetical protein, conserved 0.0053 0.0231 0.0899
Brugia malayi MBOAT family protein 0.0049 0.0207 0.0243
Toxoplasma gondii histone lysine methyltransferase SET/SUV39 0.0157 0.0861 0.3342
Echinococcus multilocularis lipoxygenase domain containing protein 0.002 0.0033 0.0031
Brugia malayi hypothetical protein 0.0053 0.0231 0.0271
Mycobacterium tuberculosis Possible conserved lipoprotein LpqK 0.004 0.0158 0.0975
Toxoplasma gondii aldehyde dehydrogenase 0.0122 0.0653 0.2525
Brugia malayi G-protein coupled receptor 0.07 0.4137 0.4893
Mycobacterium ulcerans hypothetical protein 0.017 0.094 1
Mycobacterium tuberculosis Probable cytochrome P450 143 Cyp143 0.0028 0.0086 0.0478
Echinococcus multilocularis Basic leucine zipper (bZIP) transcription 0.0071 0.0344 0.0342
Toxoplasma gondii inositol(myo)-1(or 4)-monophosphatase 2, putative 0.0037 0.0136 0.0492
Loa Loa (eye worm) neuropeptide F receptor 0.07 0.4137 0.4893
Loa Loa (eye worm) hypothetical protein 0.07 0.4137 0.4893
Echinococcus multilocularis alpha 1A adrenergic receptor 0.07 0.4137 0.4136
Trypanosoma brucei DNA polymerase IV, putative 0.007 0.0339 0.1291
Giardia lamblia CAMP-specific 3,5-cyclic phosphodiesterase 4B 0.0074 0.036 0.1766
Loa Loa (eye worm) jmjC domain-containing protein 0.006 0.0277 0.0326
Trypanosoma brucei importin beta-1 subunit, putative 0.0032 0.0108 0.0381
Schistosoma mansoni norepinephrine/norepinephrine transporter 0.0029 0.0087 0.0101
Echinococcus multilocularis histone lysine methyltransferase setb histone lysine methyltransferase eggless 0.0157 0.0861 0.0859
Loa Loa (eye worm) hypothetical protein 0.07 0.4137 0.4893
Echinococcus granulosus rhodopsin orphan GPCR 0.07 0.4137 0.4893
Toxoplasma gondii 3'5'-cyclic nucleotide phosphodiesterase domain-containing protein 0.0074 0.036 0.1372
Brugia malayi Sodium:neurotransmitter symporter family protein 0.0029 0.0087 0.0101
Loa Loa (eye worm) jmjC domain-containing protein 0.0016 0.0011 0.0011
Trypanosoma brucei DNA polymerase kappa, putative 0.007 0.0339 0.1291
Loa Loa (eye worm) hypothetical protein 0.07 0.4137 0.4893
Trypanosoma brucei PAB1-binding protein , putative 0.0053 0.0231 0.0867
Entamoeba histolytica membrane-bound O-acyltransferase (MBOAT ) family protein 0.0049 0.0207 0.0877
Echinococcus granulosus g-protein coupled receptor 0.07 0.4137 0.4893
Leishmania major hypothetical protein, conserved 0.0074 0.036 0.1403
Trichomonas vaginalis DNA helicase recq1, putative 0.0021 0.0041 0.0031
Toxoplasma gondii GAF domain-containing protein 0.004 0.0155 0.0566
Brugia malayi ImpB/MucB/SamB family protein 0.0038 0.0145 0.017
Plasmodium falciparum isocitrate dehydrogenase [NADP], mitochondrial 0.0017 0.0016 0.0131
Mycobacterium tuberculosis Inositol-1-monophosphatase SuhB 0.0033 0.0113 0.0663
Loa Loa (eye worm) hypothetical protein 0.0034 0.012 0.014
Schistosoma mansoni hypothetical protein 0.0349 0.2022 0.239
Loa Loa (eye worm) intermediate filament protein 0.0056 0.0254 0.0298
Loa Loa (eye worm) hypothetical protein 0.07 0.4137 0.4893
Plasmodium falciparum LCCL domain-containing protein 0.002 0.0033 0.056
Trichomonas vaginalis high-affinity cGMP-specific 3,5-cyclic phosphodiesterase, putative 0.0184 0.1023 0.1357
Trypanosoma brucei DNA polymerase kappa, putative 0.007 0.0339 0.1291
Leishmania major cAMP-specific phosphodiesterase, putative 0.0074 0.036 0.1403
Loa Loa (eye worm) hypothetical protein 0.0029 0.0087 0.0101
Echinococcus granulosus Ataxin 2 N terminaldomain containing protein 0.0024 0.0057 0.0065
Entamoeba histolytica fructose-1,6-bisphosphate aldolase, putative 0.0308 0.1774 1
Brugia malayi jmjC domain containing protein 0.0016 0.0011 0.0011
Onchocerca volvulus 0.07 0.4137 0.5572
Mycobacterium ulcerans hypothetical protein 0.004 0.0158 0.0847
Plasmodium falciparum ataxin-2 like protein, putative 0.0053 0.0231 0.5689
Plasmodium vivax cyclic nucleotide phosphodiesterase, putative 0.0074 0.036 0.141
Echinococcus multilocularis calcium:calmodulin dependent 3',5' cyclic 0.1415 0.8454 0.8454
Onchocerca volvulus 0.07 0.4137 0.5572
Mycobacterium leprae possible inositol monophosphatase SubH (IMPase) (inositol-1-phosphatase) (I-1-Pase ). 0.0033 0.0113 0.0366
Schistosoma mansoni serine/threonine protein kinase 0.0102 0.0531 0.0626
Trypanosoma cruzi cyclic nucleotide phosphodiesterase 0.0074 0.036 0.1403
Schistosoma mansoni sodium/chloride dependent transporter 0.0169 0.0932 0.1101
Schistosoma mansoni 6-phosphofructokinase 0.011 0.0577 0.068
Trypanosoma brucei 3', 5'-cyclic nucleotide phosphodiesterase, putative 0.0074 0.036 0.1372
Echinococcus granulosus thyrotropin releasing hormone receptor 0.07 0.4137 0.4893
Trypanosoma cruzi cytochrome P450, putative 0.0046 0.0193 0.0747
Brugia malayi MBOAT family protein 0.0049 0.0207 0.0243
Brugia malayi Death domain containing protein 0.0015 0.0002 0.000000052905
Loa Loa (eye worm) hypothetical protein 0.004 0.0158 0.0185
Brugia malayi Inositol-1 0.0037 0.0136 0.0159
Toxoplasma gondii 3'5'-cyclic nucleotide phosphodiesterase domain-containing protein 0.0074 0.036 0.1372
Loa Loa (eye worm) hhat protein 0.0049 0.0207 0.0243
Trichomonas vaginalis phosphofructokinase, putative 0.003 0.0093 0.0102
Brugia malayi hypothetical protein 0.002 0.0033 0.0037
Schistosoma mansoni rab6-interacting 0.002 0.0033 0.0037
Schistosoma mansoni lipoxygenase 0.002 0.0033 0.0037
Trichomonas vaginalis conserved hypothetical protein 0.011 0.0577 0.0755
Trichomonas vaginalis cyclic nucleotide phosphodiesterase, putative 0.0074 0.036 0.0462
Trichomonas vaginalis cAMP-specific 3,5-cyclic phosphodiesterase, putative 0.0184 0.1023 0.1357
Trypanosoma brucei glycerol uptake protein, putative 0.0049 0.0207 0.0772
Toxoplasma gondii 3'5'-cyclic nucleotide phosphodiesterase domain-containing protein 0.0074 0.036 0.1372
Trypanosoma cruzi hypothetical protein, conserved 0.0074 0.036 0.1403
Loa Loa (eye worm) hypothetical protein 0.07 0.4137 0.4893
Brugia malayi Cytochrome P450 family protein 0.0028 0.0086 0.0099
Loa Loa (eye worm) hypothetical protein 0.07 0.4137 0.4893
Trypanosoma cruzi hypothetical protein, conserved 0.0074 0.036 0.1403
Plasmodium vivax importin-beta 2, putative 0.0032 0.0108 0.0423
Schistosoma mansoni biogenic amine receptor 0.07 0.4137 0.4893
Onchocerca volvulus 0.004 0.0158 0.0211
Brugia malayi Dopamine receptor protein 1, putative (partial) 0.07 0.4137 0.4893
Trichomonas vaginalis rod cGMP-specific 3,5-cyclic phosphodiesterase, putative 0.0184 0.1023 0.1357
Echinococcus granulosus sterol O acyltransferase 1 0.0497 0.2915 0.3447
Trichomonas vaginalis rod cGMP-specific 3,5-cyclic phosphodiesterase, putative 0.0184 0.1023 0.1357
Schistosoma mansoni hypothetical protein 0.07 0.4137 0.4893
Mycobacterium tuberculosis Two component sensor histidine kinase DevS 0.004 0.0155 0.0953
Brugia malayi hypothetical protein 0.0029 0.0087 0.0101
Echinococcus granulosus tm gpcr rhodopsin 0.07 0.4137 0.4893
Onchocerca volvulus 0.07 0.4137 0.5572
Trichomonas vaginalis fructose-bisphosphate aldolase, putative 0.0308 0.1774 0.2371
Leishmania major glycerol uptake protein, putative 0.0049 0.0207 0.0805
Trypanosoma cruzi ATP-dependent 6-phosphofructokinase, glycosomal 0.011 0.0577 0.2254
Trypanosoma cruzi isocitrate dehydrogenase [NADP], mitochondrial precursor, putative 0.0017 0.0016 0.0055
Echinococcus multilocularis lysophospholipid acyltransferase 7 0.0049 0.0207 0.0205
Trichomonas vaginalis cGMP-dependent 3,5-cyclic phosphodiesterase, putative 0.0184 0.1023 0.1357
Loa Loa (eye worm) G-protein coupled receptor 0.07 0.4137 0.4893
Trypanosoma brucei unspecified product 0.0026 0.0074 0.0246
Schistosoma mansoni hypothetical protein 0.0024 0.0057 0.0065
Echinococcus multilocularis g protein coupled receptor 0.07 0.4137 0.4136
Loa Loa (eye worm) hypothetical protein 0.0049 0.0207 0.0243
Loa Loa (eye worm) hypothetical protein 0.07 0.4137 0.4893
Leishmania major importin beta-1 subunit, putative 0.0026 0.0071 0.0271
Loa Loa (eye worm) hypothetical protein 0.07 0.4137 0.4893
Schistosoma mansoni peptide (allatostatin)-like receptor 0.07 0.4137 0.4893
Trichomonas vaginalis transmembrane protein nessy, putative 0.0049 0.0207 0.0256
Echinococcus granulosus lipoxygenase domain containing protein 0.002 0.0033 0.0037
Echinococcus granulosus g protein linked acetylcholine receptor gar 2a 0.07 0.4137 0.4893
Echinococcus granulosus Transcription factor JmjC domain containing protein 0.006 0.0277 0.0326
Onchocerca volvulus 0.07 0.4137 0.5572
Plasmodium vivax multidomain scavenger receptor, putative 0.002 0.0033 0.0129
Toxoplasma gondii 3'5'-cyclic nucleotide phosphodiesterase domain-containing protein 0.0074 0.036 0.1372
Entamoeba histolytica hypothetical protein 0.0026 0.0071 0.0084
Plasmodium vivax diacylglycerol O-acyltransferase, putative 0.0049 0.0207 0.0813
Echinococcus granulosus neuropeptide Y receptor 0.07 0.4137 0.4893
Trypanosoma cruzi Lanosterol 14-alpha demethylase 0.0028 0.0086 0.0328
Schistosoma mansoni intermediate filament proteins 0.0056 0.0254 0.0298
Loa Loa (eye worm) acetyltransferase 0.0297 0.171 0.2021
Toxoplasma gondii acyl-CoA:cholesterol acyltransferase alpha ACAT1-alpha 0.0049 0.0207 0.0772
Loa Loa (eye worm) hypothetical protein 0.008 0.0395 0.0465
Trypanosoma cruzi cAMP-specific phosphodiesterase, putative 0.0074 0.036 0.1403
Toxoplasma gondii 3'5'-cyclic nucleotide phosphodiesterase domain-containing protein 0.0074 0.036 0.1372
Trypanosoma brucei glycerol uptake protein, putative 0.0049 0.0207 0.0772
Mycobacterium leprae Probable lipase LipE 0.004 0.0158 0.0983
Loa Loa (eye worm) hypothetical protein 0.07 0.4137 0.4893
Brugia malayi jmjC domain containing protein 0.006 0.0277 0.0326
Schistosoma mansoni lamin 0.0056 0.0254 0.0298
Toxoplasma gondii 3'5'-cyclic nucleotide phosphodiesterase domain-containing protein 0.0074 0.036 0.1372
Plasmodium falciparum cGMP-specific phosphodiesterase 0.0074 0.036 0.9008
Echinococcus multilocularis Transcription factor, JmjC domain containing protein 0.006 0.0277 0.0275
Schistosoma mansoni hypothetical protein 0.0349 0.2022 0.239
Echinococcus granulosus calcium:calmodulin dependent 3'5' cyclic 0.0437 0.2553 0.3018
Loa Loa (eye worm) cytoplasmic intermediate filament protein 0.003 0.0096 0.0112
Schistosoma mansoni survival motor neuron protein 0.0049 0.0208 0.0244
Leishmania major ATP-dependent phosphofructokinase 0.011 0.0577 0.2254
Brugia malayi calcium-independent alpha-latrotoxin receptor 2, putative 0.0016 0.001 0.0009
Loa Loa (eye worm) cytochrome P450 family protein 0.0046 0.0193 0.0226
Onchocerca volvulus 0.0049 0.0207 0.0277
Trypanosoma brucei DNA polymerase kappa, putative 0.0044 0.018 0.0664
Mycobacterium tuberculosis Conserved hypothetical protein 0.017 0.094 0.6344
Onchocerca volvulus Dopamine\/Ecdysteroid receptor homolog 0.07 0.4137 0.5572
Echinococcus granulosus Polycystic kidney disease protein 0.002 0.0033 0.0037
Brugia malayi G protein-coupled receptor F59B2.13 0.07 0.4137 0.4893
Echinococcus multilocularis g protein linked acetylcholine receptor gar 2a 0.07 0.4137 0.4136
Loa Loa (eye worm) hypothetical protein 0.07 0.4137 0.4893
Echinococcus granulosus serotonin transporter 0.0169 0.0932 0.1101
Trypanosoma brucei protein kinase, putative 0.0102 0.0531 0.2047
Trypanosoma cruzi DNA polymerase kappa, putative 0.007 0.0339 0.1322
Echinococcus multilocularis rhodopsin orphan GPCR 0.07 0.4137 0.4136
Mycobacterium ulcerans putative regulatory protein 0.0039 0.0148 0.0733
Trichomonas vaginalis esterase, putative 0.004 0.0158 0.019
Trichomonas vaginalis bromodomain-containing protein, putative 0.0087 0.0442 0.0573
Echinococcus multilocularis diuretic hormone 44 receptor GPRdih2 0.0016 0.001 0.0008
Trypanosoma brucei cAMP-specific phosphodiesterase 0.0184 0.1023 0.3979
Trypanosoma brucei inositol-1(or 4)-monophosphatase 1, putative 0.0037 0.0136 0.0492
Echinococcus multilocularis rhodopsin orphan GPCR 0.07 0.4137 0.4136
Loa Loa (eye worm) latrophilin receptor protein 2 0.0016 0.001 0.0009
Trypanosoma cruzi GTP-binding nuclear protein rtb2, putative 0.0024 0.0057 0.0214
Schistosoma mansoni hypothetical protein 0.0028 0.0086 0.0099
Echinococcus multilocularis mitogen activated protein kinase 0.0102 0.0531 0.0529
Echinococcus granulosus biogenic amine 5HT receptor 0.07 0.4137 0.4893
Mycobacterium tuberculosis Probable cytochrome P450 139 Cyp139 0.0028 0.0086 0.0478
Trypanosoma cruzi DNA polymerase kappa, putative 0.007 0.0339 0.1322
Trichomonas vaginalis calcium/calmodulin-dependent 3,5-cyclic nucleotide phosphodiesterase, putative 0.0114 0.0601 0.0787
Loa Loa (eye worm) CYP4Cod1 0.0046 0.0193 0.0226
Loa Loa (eye worm) adenylyl cyclase 3 0.0196 0.1101 0.13
Echinococcus multilocularis importin subunit beta 1 0.0032 0.0108 0.0106
Loa Loa (eye worm) hypothetical protein 0.0053 0.0231 0.0271
Trypanosoma brucei ATP-dependent 6-phosphofructokinase, glycosomal 0.011 0.0577 0.2227
Loa Loa (eye worm) hypothetical protein 0.07 0.4137 0.4893
Brugia malayi hypothetical protein 0.07 0.4137 0.4893
Trichomonas vaginalis phosphofructokinase, putative 0.011 0.0577 0.0755
Echinococcus granulosus 7TM GPCR rhodopsin 0.07 0.4137 0.4893
Trypanosoma cruzi mitochondrial DNA polymerase beta, putative 0.0323 0.1862 0.7292
Trypanosoma brucei isocitrate dehydrogenase [NADP], mitochondrial precursor, putative 0.0017 0.0016 0.002
Loa Loa (eye worm) hypothetical protein 0.0169 0.0932 0.1101
Trichomonas vaginalis cAMP-specific 3,5-cyclic phosphodiesterase, putative 0.0184 0.1023 0.1357
Giardia lamblia Histone acetyltransferase GCN5 0.008 0.0398 0.199
Loa Loa (eye worm) inositol-1 0.0037 0.0136 0.0159
Echinococcus multilocularis cAMP specific 3',5' cyclic phosphodiesterase 0.0074 0.036 0.0358
Trypanosoma brucei hypothetical protein, conserved 0.004 0.0158 0.0579
Toxoplasma gondii isocitrate dehydrogenase 0.0017 0.0016 0.002
Trichomonas vaginalis fructose-bisphosphate aldolase, putative 0.0308 0.1774 0.2371
Echinococcus multilocularis Polycystic kidney disease protein 0.002 0.0033 0.0031
Brugia malayi Sodium:neurotransmitter symporter family protein 0.0029 0.0087 0.0101
Trichomonas vaginalis DNA polymerase eta, putative 0.007 0.0339 0.0434
Loa Loa (eye worm) hypothetical protein 0.0029 0.0087 0.0101
Loa Loa (eye worm) neuropeptide F receptor 0.07 0.4137 0.4893
Schistosoma mansoni transcription factor LCR-F1 0.0071 0.0344 0.0405
Echinococcus multilocularis peptide (allatostatin:somatostatin) 0.07 0.4137 0.4136
Mycobacterium ulcerans putative regulatory protein 0.004 0.0155 0.0809
Trypanosoma cruzi hypothetical protein, conserved 0.0074 0.036 0.1403
Brugia malayi Corticotropin releasing factor receptor 2 precursor, putative 0.005 0.0216 0.0253
Plasmodium falciparum importin beta, putative 0.0032 0.0108 0.2498
Echinococcus granulosus cAMP specific 3'5' cyclic phosphodiesterase 0.0074 0.036 0.0424
Trichomonas vaginalis calcium/calmodulin-dependent 3,5-cyclic nucleotide phosphodiesterase, putative 0.0184 0.1023 0.1357
Trichomonas vaginalis cyclic nucleotide phosphodiesterase, putative 0.0184 0.1023 0.1357
Plasmodium vivax 3',5'-cyclic nucleotide phosphodiesterase, putative 0.0437 0.2553 1
Entamoeba histolytica membrane-bound O-acyltransferase (MBOAT ) family protein 0.0049 0.0207 0.0877
Toxoplasma gondii 6-phosphofructokinase 0.003 0.0093 0.0324
Loa Loa (eye worm) norepinephrine transporter 0.0169 0.0932 0.1101
Echinococcus multilocularis nuclear factor of activated T cells 5 0.0074 0.0363 0.0361
Plasmodium falciparum ATP-dependent 6-phosphofructokinase 0.003 0.0093 0.2123
Echinococcus multilocularis isocitrate dehydrogenase 2 (NADP+) 0.0017 0.0016 0.0014
Mycobacterium ulcerans beta-lactamase 0.004 0.0158 0.0847
Echinococcus multilocularis dro:myosuppressin receptor 0.07 0.4137 0.4136
Brugia malayi Adenylyl cyclase protein 0.0083 0.0416 0.049
Trichomonas vaginalis cat eye syndrome critical region protein 2, cscr2, putative 0.0087 0.0442 0.0573
Brugia malayi sulfakinin receptor protein 0.07 0.4137 0.4893
Echinococcus multilocularis guanine nucleotide binding protein G(s) subunit 0.0232 0.1314 0.1312
Brugia malayi G protein-coupled receptor 0.07 0.4137 0.4893
Trypanosoma cruzi hypothetical protein, conserved 0.004 0.0158 0.0612
Echinococcus granulosus neuropeptide receptor 0.07 0.4137 0.4893
Schistosoma mansoni hypothetical protein 0.002 0.0033 0.0037
Echinococcus granulosus orexin receptor type 2 0.07 0.4137 0.4893
Schistosoma mansoni family S12 unassigned peptidase (S12 family) 0.004 0.0158 0.0185
Loa Loa (eye worm) hypothetical protein 0.004 0.0158 0.0185
Brugia malayi 3'5'-cyclic nucleotide phosphodiesterase family protein 0.0074 0.036 0.0424
Brugia malayi Sodium:neurotransmitter symporter family protein 1, putative 0.0029 0.0087 0.0101
Mycobacterium tuberculosis Probable cytochrome P450 130 Cyp130 0.0028 0.0086 0.0478
Brugia malayi hypoxia-induced factor 1 0.0162 0.0893 0.1055
Schistosoma mansoni o-acyltransferase (membrane bound) domain containing protein 0.0049 0.0207 0.0243
Brugia malayi Sodium:neurotransmitter symporter family protein 0.0169 0.0932 0.1101
Schistosoma mansoni neuropeptide F-like receptor 0.07 0.4137 0.4893
Echinococcus multilocularis adenylate cyclase type IX 0.0117 0.062 0.0618
Brugia malayi Serotonin receptor 0.07 0.4137 0.4893
Echinococcus multilocularis dual 3',5' cyclic AMP and GMP phosphodiesterase 0.0184 0.1023 0.1021
Leishmania major cAMP phosphodiesterase A, putative;with=GeneDB:LinJ18_V3.1100 0.0437 0.2553 1
Mycobacterium ulcerans aldehyde dehydrogenase 0.0122 0.0653 0.6637
Loa Loa (eye worm) hypothetical protein 0.032 0.1849 0.2185
Leishmania major hypothetical protein, conserved 0.0049 0.0207 0.0805
Echinococcus multilocularis biogenic amine (5HT) receptor 0.07 0.4137 0.4136
Loa Loa (eye worm) hypothetical protein 0.07 0.4137 0.4893
Trichomonas vaginalis high-affinity cGMP-specific 3,5-cyclic phosphodiesterase, putative 0.0184 0.1023 0.1357
Mycobacterium ulcerans esterase/lipase LipP 0.004 0.0158 0.0847
Plasmodium falciparum ataxin-2 like protein, putative 0.0053 0.0231 0.5689
Schistosoma mansoni single-minded 0.0052 0.0231 0.0271
Echinococcus multilocularis microtubule associated protein 2 0.0705 0.4171 0.417
Trichomonas vaginalis conserved hypothetical protein 0.0049 0.0207 0.0256
Brugia malayi AKH receptor 0.07 0.4137 0.4893
Echinococcus granulosus neuropeptide s receptor 0.07 0.4137 0.4893
Brugia malayi G-protein-linked acetylcholine receptor protein 2, putative 0.07 0.4137 0.4893
Onchocerca volvulus 0.07 0.4137 0.5572
Echinococcus multilocularis snurportin 1 0.0342 0.1981 0.1979
Schistosoma mansoni hypothetical protein 0.0016 0.001 0.0009
Trichomonas vaginalis cyclic nucleotide phosphodiesterase, putative 0.0184 0.1023 0.1357
Trichomonas vaginalis cAMP/cGMP cyclic nucleotide phosphodiesterase, putative 0.0184 0.1023 0.1357
Giardia lamblia Hypothetical protein 0.0074 0.036 0.1766
Echinococcus granulosus phd:f box containing protein 0.0016 0.0011 0.0011
Echinococcus granulosus neuropeptides capa receptor 0.07 0.4137 0.4893
Toxoplasma gondii 3'5'-cyclic nucleotide phosphodiesterase domain-containing protein 0.0074 0.036 0.1372
Loa Loa (eye worm) hypothetical protein 0.07 0.4137 0.4893
Leishmania major mitogen activated protein kinase 4, putative;with=GeneDB:LmxM19.1440 0.0102 0.0531 0.2075
Loa Loa (eye worm) hypothetical protein 0.07 0.4137 0.4893
Toxoplasma gondii cytochrome p450 superfamily protein 0.0028 0.0086 0.0294
Brugia malayi MBOAT family protein 0.0049 0.0207 0.0243
Trichomonas vaginalis fructose-bisphosphate aldolase, putative 0.0308 0.1774 0.2371
Loa Loa (eye worm) hypothetical protein 0.07 0.4137 0.4893
Trichomonas vaginalis conserved hypothetical protein 0.004 0.0155 0.0185
Echinococcus multilocularis cAMP specific 3',5' cyclic phosphodiesterase 0.0074 0.036 0.0358
Echinococcus granulosus inositol monophosphatase 1 0.0037 0.0136 0.0159
Schistosoma mansoni biogenic amine (dopamine) receptor 0.07 0.4137 0.4893
Loa Loa (eye worm) pre-SET domain-containing protein family protein 0.1093 0.6511 0.7701
Trypanosoma cruzi myo-inositol-1(or 4)-monophosphatase 1, putative 0.0037 0.0136 0.0525
Echinococcus multilocularis RUN 0.002 0.0033 0.0031
Schistosoma mansoni protein phosphatase 2C 0.0016 0.0011 0.0011
Schistosoma mansoni rhodopsin-like orphan GPCR 0.07 0.4137 0.4893
Trichomonas vaginalis phosphofructokinase, putative 0.011 0.0577 0.0755
Loa Loa (eye worm) hypothetical protein 0.0017 0.0015 0.0016
Echinococcus granulosus 7tm_1 domain containing protein 0.07 0.4137 0.4893
Brugia malayi Dopamine receptor protein 2 0.07 0.4137 0.4893
Loa Loa (eye worm) serotonin transporter b 0.0169 0.0932 0.1101
Leishmania major mitochondrial DNA polymerase beta 0.0323 0.1862 0.7292
Echinococcus multilocularis neuropeptides capa receptor 0.07 0.4137 0.4136
Schistosoma mansoni hypothetical protein 0.0342 0.1981 0.2341
Plasmodium vivax isocitrate dehydrogenase [NADP], mitochondrial, putative 0.0017 0.0016 0.0064
Mycobacterium leprae conserved hypothetical protein 0.004 0.0155 0.0938
Echinococcus granulosus G protein coupled 5 hydroxytryptamine receptor 0.07 0.4137 0.4893
Brugia malayi MBOAT family protein 0.0049 0.0207 0.0243
Trichomonas vaginalis cyclic nucleotide phosphodiesterase, putative 0.0074 0.036 0.0462
Echinococcus granulosus high affinity cgmp specific 3' 5' cyclic 0.0074 0.036 0.0424
Brugia malayi Melatonin receptor type 1A 0.07 0.4137 0.4893
Chlamydia trachomatis fructose-6-phosphate phosphotransferase 0.003 0.0093 1
Loa Loa (eye worm) ImpB/MucB/SamB family protein 0.0038 0.0145 0.017
Schistosoma mansoni thyrotropin-releasing hormone receptor 0.07 0.4137 0.4893
Loa Loa (eye worm) hypothetical protein 0.07 0.4137 0.4893
Mycobacterium tuberculosis Probable cytochrome P450 144 Cyp144 0.0028 0.0086 0.0478
Trichomonas vaginalis cGMP-dependent 3,5-cyclic phosphodiesterase, putative 0.0074 0.036 0.0462
Plasmodium vivax hypothetical protein, conserved 0.004 0.0158 0.062
Loa Loa (eye worm) hypothetical protein 0.0169 0.0932 0.1101
Trypanosoma cruzi importin beta-1 subunit, putative 0.0026 0.0071 0.0271
Echinococcus granulosus G protein coupled receptor 139 0.07 0.4137 0.4893
Loa Loa (eye worm) hypothetical protein 0.0169 0.0932 0.1101
Loa Loa (eye worm) diacylglycerol acyltransferase 0.0049 0.0207 0.0243
Brugia malayi hypothetical protein 0.07 0.4137 0.4893
Schistosoma mansoni importin beta-1 0.0032 0.0108 0.0125
Toxoplasma gondii 3'5'-cyclic nucleotide phosphodiesterase domain-containing protein 0.0437 0.2553 1
Toxoplasma gondii hypothetical protein 0.004 0.0155 0.0566
Mycobacterium tuberculosis Probable cytochrome P450 monooxygenase 142 Cyp142 0.0028 0.0086 0.0478
Onchocerca volvulus 0.07 0.4137 0.5572
Schistosoma mansoni sodium/chloride dependent transporter 0.0029 0.0087 0.0101
Loa Loa (eye worm) membrane bound O-acyltransferase domain containing 1 0.0049 0.0207 0.0243
Schistosoma mansoni polycystin 1-related 0.002 0.0033 0.0037
Echinococcus granulosus sodium:chloride dependent neurotransmitter 0.0029 0.0087 0.0101
Echinococcus multilocularis neuropeptide Y receptor 0.07 0.4137 0.4136
Brugia malayi latrophilin 2 splice variant baaae 0.0034 0.012 0.014
Echinococcus multilocularis beta LACTamase domain containing family member 0.004 0.0158 0.0156
Echinococcus multilocularis musashi 0.0056 0.0254 0.0252
Mycobacterium tuberculosis Possible penicillin-binding protein 0.0258 0.1473 1
Entamoeba histolytica hypothetical protein, conserved 0.0049 0.0207 0.0877
Brugia malayi Pre-SET motif family protein 0.1093 0.6511 0.7701
Echinococcus multilocularis neuropeptides capa receptor 0.07 0.4137 0.4136
Trichomonas vaginalis D-aminoacylase, putative 0.004 0.0158 0.019
Trypanosoma brucei GTP-binding nuclear protein rtb2, putative 0.0024 0.0057 0.018
Plasmodium vivax GTP-binding nuclear protein RAN/TC4, putative 0.0024 0.0057 0.0223
Onchocerca volvulus 0.07 0.4137 0.5572
Trichomonas vaginalis calcium/calmodulin-dependent 3,5-cyclic nucleotide phosphodiesterase, putative 0.0184 0.1023 0.1357
Trichomonas vaginalis calcium/calmodulin-dependent 3,5-cyclic nucleotide phosphodiesterase, putative 0.0074 0.036 0.0462
Loa Loa (eye worm) hypothetical protein 0.07 0.4137 0.4893
Schistosoma mansoni o-acyltransferase (membrane bound) domain containing protein 0.0049 0.0207 0.0243
Brugia malayi 3'5'-cyclic nucleotide phosphodiesterase family protein 0.0114 0.0601 0.0708
Schistosoma mansoni lipoxygenase 0.0055 0.0246 0.0289
Schistosoma mansoni hypothetical protein 0.0016 0.001 0.0009
Trichomonas vaginalis fructose-bisphosphate aldolase, putative 0.0308 0.1774 0.2371
Schistosoma mansoni hypothetical protein 0.0071 0.0344 0.0405
Echinococcus multilocularis guanine nucleotide binding protein G(s) subunit 0.0232 0.1314 0.1312
Echinococcus granulosus adenylate cyclase type IX 0.0117 0.062 0.0731
Brugia malayi Latrophilin receptor protein 2 0.0016 0.001 0.0009
Trypanosoma brucei DNA polymerase kappa, putative 0.0034 0.0122 0.0435
Brugia malayi Probable 3',5'-cyclic phosphodiesterase C32E12.2, putative 0.0114 0.0601 0.0708
Brugia malayi Intermediate filament tail domain containing protein 0.0056 0.0254 0.0298
Loa Loa (eye worm) hypothetical protein 0.0049 0.0207 0.0243
Echinococcus granulosus survival motor neuron protein 1 0.0239 0.1356 0.1602
Loa Loa (eye worm) hypothetical protein 0.0056 0.0254 0.0298
Leishmania major glycerol uptake protein, putative 0.0049 0.0207 0.0805
Brugia malayi Hypothetical 52.5 kDa protein ZK945.1 in chromosome II, putative 0.004 0.0158 0.0185
Mycobacterium ulcerans fusion of enoyl-CoA hydratase, EchA21 and lipase, LipE 0.004 0.0158 0.0847
Loa Loa (eye worm) hypothetical protein 0.0016 0.0011 0.0011
Loa Loa (eye worm) hypothetical protein 0.004 0.0158 0.0185
Brugia malayi hypothetical protein 0.07 0.4137 0.4893
Trypanosoma brucei unspecified product 0.0026 0.0074 0.0246
Echinococcus granulosus snurportin 1 0.0342 0.1981 0.2341
Echinococcus granulosus high affinity cAMP specific 3'5' cyclic 0.0074 0.036 0.0424
Trypanosoma brucei DNA polymerase IV, putative 0.007 0.0339 0.1291
Loa Loa (eye worm) hypothetical protein 0.07 0.4137 0.4893
Toxoplasma gondii acyl-CoA:diacylglycerol acyltransferase 1-related enzyme 0.0049 0.0207 0.0772
Loa Loa (eye worm) hypothetical protein 0.004 0.0158 0.0185
Brugia malayi PAS domain containing protein 0.0052 0.0231 0.0271
Echinococcus multilocularis 0.0028 0.0086 0.0084
Leishmania major aldehyde dehydrogenase, mitochondrial precursor 0.0122 0.0653 0.2552
Echinococcus granulosus cAMP and cAMP inhibited cGMP 3'5' cyclic 0.0114 0.0601 0.0708
Loa Loa (eye worm) hypothetical protein 0.07 0.4137 0.4893
Schistosoma mansoni rhodopsin-like orphan GPCR 0.07 0.4137 0.4893
Loa Loa (eye worm) hypothetical protein 0.0074 0.036 0.0424
Schistosoma mansoni hypothetical protein 0.07 0.4137 0.4893
Echinococcus multilocularis G protein coupled receptor 139 0.07 0.4137 0.4136
Echinococcus granulosus pyroglutamylated rfamide peptide receptor 0.07 0.4137 0.4893
Loa Loa (eye worm) cytochrome P450 0.0028 0.0086 0.0099
Echinococcus granulosus diuretic hormone 44 receptor GPRdih2 0.0016 0.001 0.0009
Toxoplasma gondii hypothetical protein 0.004 0.0155 0.0566
Trypanosoma cruzi DNA polymerase beta thumb, putative 0.0045 0.0188 0.073
Schistosoma mansoni cytochrome P450 0.0028 0.0086 0.0099
Trichomonas vaginalis CMGC family protein kinase 0.0102 0.0531 0.0693
Brugia malayi hypothetical protein 0.07 0.4137 0.4893
Echinococcus granulosus tm gpcr rhodopsin 0.07 0.4137 0.4893
Echinococcus granulosus cadherin EGF LAG seven pass G type receptor 0.0016 0.001 0.0009
Schistosoma mansoni histamine-responsive GPCR (AAF21638) 0.07 0.4137 0.4893
Leishmania major mitogen activated protein kinase, putative,map kinase, putative 0.0102 0.0531 0.2075
Schistosoma mansoni Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) 0.0232 0.1314 0.1552
Echinococcus multilocularis rhodopsin orphan GPCR 0.07 0.4137 0.4136
Schistosoma mansoni rhodopsin-like orphan GPCR 0.07 0.4137 0.4893
Mycobacterium tuberculosis Probable cytochrome P450 124 Cyp124 0.0028 0.0086 0.0478
Trypanosoma cruzi mitochondrial DNA polymerase beta, putative 0.0323 0.1862 0.7292
Schistosoma mansoni histone-lysine n-methyltransferase suv9 0.0157 0.0861 0.1016
Brugia malayi hypothetical protein 0.0176 0.0976 0.1152
Schistosoma mansoni sodium-dependent neurotransmitter transporter 0.0029 0.0087 0.0101
Schistosoma mansoni sodium/chloride dependent neurotransmitter transporter 0.0029 0.0087 0.0101
Loa Loa (eye worm) hypothetical protein 0.0029 0.0087 0.0101
Schistosoma mansoni terminal deoxycytidyl transferase 0.0038 0.0145 0.017
Brugia malayi MBOAT family protein 0.0049 0.0207 0.0243
Echinococcus multilocularis terminal deoxycytidyl transferase rev1 0.0038 0.0145 0.0143
Mycobacterium tuberculosis Conserved protein 0.004 0.0158 0.0975
Entamoeba histolytica hypothetical protein 0.0071 0.0344 0.1673
Trichomonas vaginalis high-affinity cGMP-specific 3,5-cyclic phosphodiesterase, putative 0.0114 0.0601 0.0787
Trichomonas vaginalis CMGC family protein kinase 0.0102 0.0531 0.0693
Loa Loa (eye worm) hypothetical protein 0.07 0.4137 0.4893
Loa Loa (eye worm) cytochrome P450 family protein 0.0046 0.0193 0.0226
Loa Loa (eye worm) GTP-binding regulatory protein Gs alpha-S chain 0.0232 0.1314 0.1552
Loa Loa (eye worm) hypothetical protein 0.0114 0.0601 0.0708
Echinococcus multilocularis tachykinin peptides receptor 99D 0.07 0.4137 0.4136
Onchocerca volvulus 0.07 0.4137 0.5572
Loa Loa (eye worm) hypothetical protein 0.0015 0.0003 0.0001
Entamoeba histolytica acetyltransferase, GNAT family 0.008 0.0398 0.199
Loa Loa (eye worm) hypothetical protein 0.07 0.4137 0.4893
Loa Loa (eye worm) hypothetical protein 0.0044 0.018 0.021
Onchocerca volvulus 0.07 0.4137 0.5572
Echinococcus multilocularis bloom syndrome protein 0.0021 0.0041 0.0039
Echinococcus granulosus membrane bound acyltransferase:hhat 0.0049 0.0207 0.0243
Loa Loa (eye worm) Sodium:neurotransmitter symporter family protein 0.0029 0.0087 0.0101
Onchocerca volvulus 0.002 0.0033 0.0042
Echinococcus granulosus rhodopsin orphan GPCR 0.07 0.4137 0.4893
Entamoeba histolytica phosphofructokinase, putative 0.011 0.0577 0.3031
Trichomonas vaginalis cAMP and cAMP-inhibited cGMP 3,5-cyclic phosphodiesterase, putative 0.0074 0.036 0.0462
Trichomonas vaginalis phosphofructokinase, putative 0.011 0.0577 0.0755
Schistosoma mansoni hypothetical protein 0.07 0.4137 0.4893
Plasmodium vivax 6-phosphofructokinase, putative 0.003 0.0093 0.0366
Brugia malayi neuropeptide F receptor 0.07 0.4137 0.4893
Trypanosoma cruzi mitochondrial DNA polymerase beta-PAK, putative 0.0045 0.0188 0.073
Echinococcus granulosus o acyltransferase membrane bound domain 0.0049 0.0207 0.0243
Plasmodium vivax JmjC domain containing protein 0.0016 0.0011 0.0044
Echinococcus multilocularis orexin receptor type 2 0.07 0.4137 0.4136
Echinococcus multilocularis transfer RNA-Lys 0.0039 0.0148 0.0146
Loa Loa (eye worm) phosphofructokinase 0.011 0.0577 0.068
Plasmodium vivax ataxin-2 like protein, putative 0.0053 0.0231 0.0907
Onchocerca volvulus 0.0157 0.0861 0.1157
Onchocerca volvulus 0.0029 0.0087 0.0115
Brugia malayi beta-lactamase 0.004 0.0158 0.0185
Onchocerca volvulus 0.07 0.4137 0.5572
Schistosoma mansoni opsin-like receptor 0.07 0.4137 0.4893
Echinococcus granulosus histone acetyltransferase KAT2B 0.0289 0.166 0.1961
Echinococcus granulosus neuropeptide Y receptor 0.07 0.4137 0.4893
Toxoplasma gondii Sodium:neurotransmitter symporter family protein 0.0029 0.0087 0.0299
Toxoplasma gondii 3'5'-cyclic nucleotide phosphodiesterase domain-containing protein 0.0074 0.036 0.1372
Mycobacterium tuberculosis Probable hydrolase 0.004 0.0158 0.0975
Echinococcus granulosus 6 phosphofructokinase 0.011 0.0577 0.068
Echinococcus granulosus rhodopsin orphan GPCR 0.07 0.4137 0.4893
Mycobacterium tuberculosis Probable cytochrome P450 136 Cyp136 0.0028 0.0086 0.0478
Trichomonas vaginalis cAMP-specific phosphodiesterase, putative 0.0184 0.1023 0.1357
Schistosoma mansoni neuropeptide f receptor 76f 0.07 0.4137 0.4893
Plasmodium falciparum transporter, putative 0.0029 0.0087 0.1962
Echinococcus granulosus lamin dm0 0.0056 0.0254 0.0298
Trichomonas vaginalis phosphofructokinase, putative 0.003 0.0093 0.0102
Loa Loa (eye worm) calcium/calmodulin-stimulated cyclic nucleotide phosphodiesterase 0.0074 0.036 0.0424
Echinococcus multilocularis g protein coupled receptor 0.07 0.4137 0.4136
Trichomonas vaginalis cGMP-specific 3,5-cyclic phosphodiesterase, putative 0.0184 0.1023 0.1357
Treponema pallidum sodium- and chloride- dependent transporter 0.0169 0.0932 0.4993
Loa Loa (eye worm) hypothetical protein 0.0029 0.0087 0.0101
Mycobacterium ulcerans putative regulatory protein 0.004 0.0155 0.0809
Trypanosoma brucei DNA polymerase kappa, putative 0.007 0.0339 0.1291
Echinococcus granulosus Solute carrier family 22 5 0.1086 0.6468 0.765
Trichomonas vaginalis cGMP-inhibited 3,5-cyclic phosphodiesterase, putative 0.0184 0.1023 0.1357
Plasmodium vivax phosphodiesterase gamma, putative 0.0074 0.036 0.141
Trichomonas vaginalis inositol monophosphatase, putative 0.0037 0.0136 0.016
Loa Loa (eye worm) gonadotropin-releasing hormone receptor 2 0.07 0.4137 0.4893
Echinococcus multilocularis lamin dm0 0.0056 0.0254 0.0252
Trypanosoma cruzi JmjC domain, hydroxylase, putative 0.0016 0.0011 0.0035
Echinococcus granulosus uncharacterized sodium dependent transporter 0.0029 0.0087 0.0101
Echinococcus granulosus ankyrin repeat and death domain containing protein 0.0015 0.0002 0.000000052905
Trichomonas vaginalis calcium/calmodulin-dependent 3',5'-cyclic nucleotide phosphodiesterase, putative 0.0074 0.036 0.0462
Echinococcus multilocularis sodium:chloride dependent neurotransmitter 0.0029 0.0087 0.0085
Trypanosoma brucei mitogen activated protein kinase 4, putative 0.0102 0.0531 0.2047
Trypanosoma cruzi DNA polymerase eta, putative 0.0038 0.0145 0.0561
Echinococcus granulosus hypothetical protein 0.07 0.4137 0.4893
Trypanosoma cruzi hypothetical protein, conserved 0.0074 0.036 0.1403
Trichomonas vaginalis high-affinity cGMP-specific 3,5-cyclic phosphodiesterase, putative 0.0074 0.036 0.0462
Mycobacterium tuberculosis Cytochrome P450 51 Cyp51 (CYPL1) (P450-L1A1) (sterol 14-alpha demethylase) (lanosterol 14-alpha demethylase) (P450-14DM) 0.0028 0.0086 0.0478
Plasmodium falciparum diacylglycerol O-acyltransferase 0.0049 0.0207 0.5068
Trichomonas vaginalis cGMP-specific 3,5-cyclic phosphodiesterase, putative 0.0184 0.1023 0.1357
Onchocerca volvulus 0.0056 0.0254 0.034
Loa Loa (eye worm) hypoxia-induced factor 1 0.0162 0.0893 0.1055
Loa Loa (eye worm) hypothetical protein 0.07 0.4137 0.4893
Echinococcus multilocularis o acyltransferase (membrane bound) domain 0.0049 0.0207 0.0205
Loa Loa (eye worm) hypothetical protein 0.07 0.4137 0.4893
Trichomonas vaginalis high-affinity cGMP-specific 3,5-cyclic phosphodiesterase, putative 0.0184 0.1023 0.1357
Echinococcus multilocularis g protein coupled receptor 0.07 0.4137 0.4136
Mycobacterium tuberculosis Conserved protein 0.004 0.0158 0.0975
Echinococcus multilocularis survival motor neuron protein 1 0.0239 0.1356 0.1354
Trypanosoma cruzi cAMP specific phosphodiesterase, putative 0.0144 0.0782 0.3057
Trichomonas vaginalis DNA polymerase IV / kappa, putative 0.007 0.0339 0.0434
Loa Loa (eye worm) hypothetical protein 0.0029 0.0087 0.0101
Trichomonas vaginalis cGMP-dependent 3,5-cyclic phosphodiesterase, putative 0.0114 0.0601 0.0787
Toxoplasma gondii 3'5'-cyclic nucleotide phosphodiesterase domain-containing protein 0.0074 0.036 0.1372
Loa Loa (eye worm) hypothetical protein 0.004 0.0158 0.0185
Trypanosoma cruzi mitogen-activated protein kinase 11, putative 0.0102 0.0531 0.2075
Brugia malayi gonadotropin-releasing hormone receptor 2 0.07 0.4137 0.4893
Echinococcus granulosus calcium:calmodulin dependent 3'5' cyclic 0.1415 0.8454 1
Echinococcus multilocularis rhodopsin orphan GPCR 0.07 0.4137 0.4136
Trichomonas vaginalis importin beta-1, putative 0.0026 0.0071 0.0072
Schistosoma mansoni neuropeptide receptor 0.07 0.4137 0.4893
Brugia malayi bHLH-PAS transcription factor 0.0039 0.0148 0.0173
Brugia malayi putative neuropeptide receptor NPR1 0.07 0.4137 0.4893
Toxoplasma gondii 3'5'-cyclic nucleotide phosphodiesterase domain-containing protein 0.0437 0.2553 1
Echinococcus multilocularis rhodopsin orphan GPCR 0.07 0.4137 0.4136
Echinococcus multilocularis GPCR, family 2 0.0016 0.001 0.0008
Brugia malayi Bloom's syndrome protein homolog 0.0021 0.0041 0.0046
Trichomonas vaginalis fructose-bisphosphate aldolase, putative 0.0308 0.1774 0.2371
Schistosoma mansoni amine GPCR 0.07 0.4137 0.4893
Brugia malayi follicle stimulating hormone receptor 0.0947 0.5633 0.6662
Schistosoma mansoni cgmp-dependent 35-cyclic phosphodiesterase 0.0114 0.0601 0.0708
Echinococcus multilocularis protein cysteine N palmitoyltransferase 0.0049 0.0207 0.0205
Trypanosoma cruzi DNA polymerase kappa, putative 0.007 0.0339 0.1322
Toxoplasma gondii GTP-binding nuclear protein ran/tc4 0.0024 0.0057 0.018
Brugia malayi beta-lactamase family protein 0.004 0.0158 0.0185
Trypanosoma cruzi mitogen activated protein kinase 2, putative 0.0102 0.0531 0.2075
Loa Loa (eye worm) hypothetical protein 0.0016 0.001 0.0009
Echinococcus granulosus NADP dependent isocitrate dehydrogenase 0.0017 0.0016 0.0017
Trypanosoma cruzi mitogen-activated protein kinase 11, putative 0.0102 0.0531 0.2075
Trichomonas vaginalis cAMP and cAMP-inhibited cGMP 3,5-cyclic phosphodiesterase, putative 0.0144 0.0782 0.1032
Trypanosoma cruzi mitogen activated protein kinase 4, putative 0.0102 0.0531 0.2075
Onchocerca volvulus 0.0169 0.0932 0.1254
Leishmania major hypothetical protein, conserved 0.0016 0.0011 0.0035
Trypanosoma brucei Lanosterol 14-alpha demethylase 0.0028 0.0086 0.0294
Onchocerca volvulus 0.0029 0.0087 0.0115
Mycobacterium ulcerans lipase LipD 0.004 0.0158 0.0847
Echinococcus granulosus Jumonji AT rich interactive domain 1B 0.0016 0.0011 0.0011
Plasmodium falciparum 3',5'-cyclic nucleotide phosphodiesterase, putative 0.0074 0.036 0.9008
Loa Loa (eye worm) nucleolar RNA-associated protein alpha 0.0342 0.1981 0.2341
Trypanosoma cruzi GTP-binding nuclear protein rtb2, putative 0.0024 0.0057 0.0214
Schistosoma mansoni diacylglycerol O-acyltransferase 1 0.0049 0.0207 0.0243
Loa Loa (eye worm) cytochrome P450 family protein 0.0066 0.0312 0.0366
Onchocerca volvulus 0.1244 0.7423 1
Trypanosoma cruzi cytochrome p450-like protein, putative 0.0028 0.0086 0.0328
Schistosoma mansoni high-affinity cgmp-specific 35-cyclic phosphodiesterase 0.0074 0.036 0.0424
Echinococcus granulosus guanine nucleotide binding protein Gs subunit 0.0232 0.1314 0.1552
Plasmodium vivax 3',5'-cyclic nucleotide phosphodiesterase, putative 0.0074 0.036 0.141
Schistosoma mansoni inositol monophosphatase 0.0037 0.0136 0.0159
Echinococcus multilocularis growth hormone secretagogue receptor type 1 0.07 0.4137 0.4136
Schistosoma mansoni camp-specific 35-cyclic phosphodiesterase 0.0074 0.036 0.0424
Plasmodium falciparum GAF domain-related protein, putative 0.004 0.0155 0.3714
Loa Loa (eye worm) hypothetical protein 0.0083 0.0416 0.049
Loa Loa (eye worm) hypothetical protein 0.004 0.0155 0.0181
Brugia malayi acetyltransferase, GNAT family protein 0.0297 0.171 0.2021
Schistosoma mansoni biogenic amine (dopamine) receptor 0.07 0.4137 0.4893
Chlamydia trachomatis fructose-6-phosphate phosphotransferase 0.003 0.0093 1
Brugia malayi Cytochrome P450 family protein 0.0066 0.0312 0.0366
Schistosoma mansoni hypothetical protein 0.0049 0.0207 0.0243
Schistosoma mansoni ubiquitously transcribed sex (X/Y) chromosome tetratricopeptide repeat protein-related 0.0016 0.0011 0.0011
Brugia malayi polk-prov protein 0.0044 0.018 0.021
Loa Loa (eye worm) hypothetical protein 0.0176 0.0976 0.1152
Loa Loa (eye worm) hypothetical protein 0.07 0.4137 0.4893
Schistosoma mansoni rhodopsin-like orphan GPCR 0.07 0.4137 0.4893
Loa Loa (eye worm) hypothetical protein 0.07 0.4137 0.4893
Echinococcus granulosus protein cysteine N palmitoyltransferase 0.0049 0.0207 0.0243
Schistosoma mansoni rhodopsin-like orphan GPCR 0.07 0.4137 0.4893
Onchocerca volvulus 0.004 0.0158 0.0211
Echinococcus multilocularis adenylate cyclase 9 0.0083 0.0416 0.0415
Loa Loa (eye worm) hypothetical protein 0.0074 0.036 0.0424
Loa Loa (eye worm) hypothetical protein 0.0027 0.0078 0.009
Brugia malayi jmjC domain containing protein 0.0016 0.0011 0.0011
Leishmania major cytochrome p450-like protein 0.0046 0.0193 0.0747
Trypanosoma brucei DNA polymerase kappa, putative 0.007 0.0339 0.1291
Echinococcus multilocularis serotonin receptor 0.07 0.4137 0.4136
Loa Loa (eye worm) hypothetical protein 0.0016 0.0011 0.0011
Loa Loa (eye worm) hypothetical protein 0.0032 0.0108 0.0125
Brugia malayi MAP kinase sur-1 0.0102 0.0531 0.0626
Loa Loa (eye worm) hypothetical protein 0.0018 0.0021 0.0023
Toxoplasma gondii HEAT repeat-containing protein 0.0032 0.0108 0.0381
Loa Loa (eye worm) G-protein coupled receptor 0.07 0.4137 0.4893
Brugia malayi 3'5'-cyclic nucleotide phosphodiesterase family protein 0.0074 0.036 0.0424
Trichomonas vaginalis cone cGMP-specific 3,5-cyclic phosphodiesterase, putative 0.0184 0.1023 0.1357
Giardia lamblia Kinase, CMGC MAPK 0.0102 0.0531 0.2764
Trichomonas vaginalis DNA helicase recq, putative 0.0021 0.0041 0.0031
Mycobacterium ulcerans two component sensor histidine kinase DevS 0.004 0.0155 0.0809
Loa Loa (eye worm) hypothetical protein 0.07 0.4137 0.4893
Echinococcus multilocularis Ataxin 2, N terminal,domain containing protein 0.0024 0.0057 0.0055
Echinococcus multilocularis 7TM GPCR, rhodopsin 0.07 0.4137 0.4136
Echinococcus multilocularis g protein linked acetylcholine receptor gar 2a 0.07 0.4137 0.4136
Echinococcus multilocularis neuropeptide Y receptor 0.07 0.4137 0.4136
Trypanosoma cruzi cAMP specific phosphodiesterase, putative 0.0184 0.1023 0.4
Schistosoma mansoni biogenic amine (5HT) receptor 0.07 0.4137 0.4893
Echinococcus multilocularis diacylglycerol O acyltransferase 1 0.0049 0.0207 0.0205
Schistosoma mansoni myosin xvIII 0.07 0.4137 0.4893
Toxoplasma gondii CMGC kinase, MAPK family (ERK) MAPK-1 0.0102 0.0531 0.2047
Echinococcus granulosus neuropeptide receptor A26 0.07 0.4137 0.4893
Echinococcus multilocularis JmjC domain containing protein 4 0.0016 0.0011 0.0009
Echinococcus granulosus histone lysine methyltransferase setb 0.0157 0.0861 0.1016
Toxoplasma gondii BRCA1 C Terminus (BRCT) domain-containing protein 0.002 0.0034 0.009
Mycobacterium tuberculosis Probable cytochrome P450 123 Cyp123 0.0028 0.0086 0.0478
Mycobacterium leprae conserved hypothetical protein 0.004 0.0158 0.0983
Entamoeba histolytica phosphofructokinase, putative 0.011 0.0577 0.3031
Onchocerca volvulus 0.008 0.0395 0.053
Loa Loa (eye worm) hypothetical protein 0.07 0.4137 0.4893
Schistosoma mansoni opsin-like receptor 0.07 0.4137 0.4893
Loa Loa (eye worm) hypothetical protein 0.07 0.4137 0.4893
Schistosoma mansoni camp-specific 35-cyclic phosphodiesterase 0.0074 0.036 0.0424
Trypanosoma brucei 3', 5'-cyclic nucleotide phosphodiesterase, putative 0.0074 0.036 0.1372
Mycobacterium tuberculosis Probable esterase LipL 0.004 0.0158 0.0975
Loa Loa (eye worm) 6-phosphofructokinase 0.011 0.0577 0.068
Schistosoma mansoni norepinephrine/norepinephrine transporter 0.0169 0.0932 0.1101
Mycobacterium tuberculosis Probable cytochrome P450 132 Cyp132 0.0028 0.0086 0.0478
Brugia malayi Calcitonin receptor-like protein seb-1 0.005 0.0216 0.0253
Echinococcus granulosus guanine nucleotide binding protein Gs subunit 0.0232 0.1314 0.1552
Echinococcus multilocularis o acyltransferase (membrane bound) domain 0.0049 0.0207 0.0205
Mycobacterium tuberculosis Probable fructose-bisphosphate aldolase Fba 0.015 0.0823 0.5536
Echinococcus multilocularis cadherin EGF LAG seven pass G type receptor 0.0016 0.001 0.0008
Brugia malayi Importin beta-1 subunit 0.0032 0.0108 0.0125
Echinococcus granulosus peptide allatostatin:somatostatin 0.07 0.4137 0.4893
Brugia malayi hypothetical protein 0.07 0.4137 0.4893
Echinococcus multilocularis neuropeptide receptor 0.07 0.4137 0.4136
Loa Loa (eye worm) hypothetical protein 0.07 0.4137 0.4893
Entamoeba histolytica hypothetical protein 0.0071 0.0344 0.1673
Echinococcus multilocularis g-protein coupled receptor 0.07 0.4137 0.4136
Echinococcus granulosus adenylate cyclase 9 0.0083 0.0416 0.049
Echinococcus granulosus growth hormone secretagogue receptor type 1 0.07 0.4137 0.4893
Onchocerca volvulus 0.07 0.4137 0.5572
Echinococcus granulosus somatostatin receptor 0.07 0.4137 0.4893
Onchocerca volvulus 0.07 0.4137 0.5572
Giardia lamblia DINP protein human, muc B family 0.0046 0.0193 0.0796
Loa Loa (eye worm) hypothetical protein 0.002 0.0033 0.0037
Echinococcus granulosus sex peptide receptor 0.07 0.4137 0.4893
Loa Loa (eye worm) intermediate filament tail domain-containing protein 0.0056 0.0254 0.0298
Loa Loa (eye worm) hypothetical protein 0.0239 0.1356 0.1602
Toxoplasma gondii histone lysine acetyltransferase GCN5-A 0.0087 0.0442 0.1697
Plasmodium falciparum phosphodiesterase gamma, putative 0.0074 0.036 0.9008
Echinococcus granulosus tm gpcr rhodopsin 0.07 0.4137 0.4893
Mycobacterium tuberculosis Probable cytochrome P450 140 Cyp140 0.0028 0.0086 0.0478
Trichomonas vaginalis phosphofructokinase, putative 0.003 0.0093 0.0102
Entamoeba histolytica phosphofructokinase, putative 0.011 0.0577 0.3031
Loa Loa (eye worm) pigment dispersing factor receptor c 0.005 0.0216 0.0253
Loa Loa (eye worm) jmjC domain-containing protein 0.0016 0.0011 0.0011
Onchocerca volvulus 0.0039 0.0148 0.0197
Brugia malayi GnHR receptor homolog 0.07 0.4137 0.4893
Loa Loa (eye worm) MBOAT family protein 0.0049 0.0207 0.0243
Trichomonas vaginalis cone cGMP-specific 3,5-cyclic phosphodiesterase, putative 0.0184 0.1023 0.1357
Schistosoma mansoni rhodopsin-like orphan GPCR 0.07 0.4137 0.4893
Brugia malayi phosphofructokinase 0.011 0.0577 0.068
Schistosoma mansoni biogenic amine receptor 0.07 0.4137 0.4893
Leishmania major cytochrome p450-like protein 0.0028 0.0086 0.0328
Schistosoma mansoni o-acyltransferase (membrane bound) domain containing protein 0.0049 0.0207 0.0243
Trypanosoma cruzi PAB1-binding protein , putative 0.0053 0.0231 0.0899
Echinococcus multilocularis pyroglutamylated rfamide peptide receptor 0.07 0.4137 0.4136
Echinococcus multilocularis membrane bound acyltransferase:hhat 0.0049 0.0207 0.0205
Trypanosoma brucei mitochondrial DNA polymerase beta-PAK 0.0153 0.0836 0.3246
Brugia malayi ImpB/MucB/SamB family protein 0.0038 0.0145 0.017
Entamoeba histolytica hypothetical protein 0.0071 0.0344 0.1673
Trichomonas vaginalis penicillin-binding protein, putative 0.004 0.0158 0.019
Plasmodium falciparum GTP-binding nuclear protein RAN/TC4 0.0024 0.0057 0.1178
Schistosoma mansoni phosphatidylserine receptor 0.0016 0.0011 0.0011
Toxoplasma gondii phosphofructokinase domain-containing protein 0.003 0.0093 0.0324
Loa Loa (eye worm) hypothetical protein 0.0055 0.0248 0.0291
Schistosoma mansoni microtubule-associated protein tau 0.0705 0.4171 0.4933
Echinococcus multilocularis cytoplasmic intermediate filament protein 0.0027 0.0078 0.0076
Schistosoma mansoni high-affinity cgmp-specific 35-cyclic phosphodiesterase 0.0074 0.036 0.0424
Schistosoma mansoni ancient conserved domain protein 2 (cyclin m2) 0.07 0.4137 0.4893
Echinococcus granulosus dna polymerase eta 0.0038 0.0145 0.017
Echinococcus granulosus rhodopsin orphan GPCR 0.07 0.4137 0.4893
Schistosoma mansoni neuropeptide F-like receptor 0.07 0.4137 0.4893
Brugia malayi jmjC domain containing protein 0.0016 0.0011 0.0011
Toxoplasma gondii phosphofructokinase PFKII 0.003 0.0093 0.0324
Echinococcus granulosus RUN 0.002 0.0033 0.0037
Toxoplasma gondii 3'5'-cyclic nucleotide phosphodiesterase domain-containing protein 0.0074 0.036 0.1372
Loa Loa (eye worm) hypothetical protein 0.07 0.4137 0.4893
Mycobacterium tuberculosis Probable lipase LipD 0.004 0.0158 0.0975
Brugia malayi hypothetical protein 0.0123 0.0657 0.0774
Toxoplasma gondii Sodium:neurotransmitter symporter family protein 0.0029 0.0087 0.0299
Echinococcus multilocularis serotonin transporter 0.0169 0.0932 0.0931
Trypanosoma brucei DNA polymerase eta, putative 0.0038 0.0145 0.0528
Brugia malayi hypothetical protein 0.0239 0.1356 0.1602
Trichomonas vaginalis fructose-bisphosphate aldolase, putative 0.0308 0.1774 0.2371
Schistosoma mansoni biogenic amine (5HT) receptor 0.07 0.4137 0.4893
Loa Loa (eye worm) follicle stimulating hormone receptor 0.0947 0.5633 0.6662
Schistosoma mansoni DNA polymerase eta 0.0038 0.0145 0.017
Mycobacterium tuberculosis Probable conserved lipoprotein 0.004 0.0158 0.0975
Loa Loa (eye worm) hypothetical protein 0.07 0.4137 0.4893
Schistosoma mansoni amine GPCR 0.07 0.4137 0.4893
Loa Loa (eye worm) unidentified vitellogenin-linked transcript protein 6 0.07 0.4137 0.4893
Schistosoma mansoni phd/f-box containing protein 0.0016 0.0011 0.0011
Echinococcus multilocularis Membrane bound O acyl transferase, MBOAT 0.0049 0.0207 0.0205
Schistosoma mansoni peptide (allatostatin/somatostatin)-like receptor 0.07 0.4137 0.4893
Brugia malayi Dopamine receptor protein 1 0.07 0.4137 0.4893
Echinococcus granulosus serotonin receptor 0.07 0.4137 0.4893
Schistosoma mansoni Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) 0.0232 0.1314 0.1552
Echinococcus granulosus cytoplasmic intermediate filament protein 0.0027 0.0078 0.009
Echinococcus multilocularis tm gpcr rhodopsin gpcr rhodopsin superfamily 0.07 0.4137 0.4136
Trypanosoma brucei isocitrate dehydrogenase, putative 0.0017 0.0016 0.002
Trypanosoma cruzi mitochondrial DNA polymerase beta-PAK, putative 0.0055 0.0248 0.0964
Schistosoma mansoni sodium/chloride dependent neurotransmitter transporter 0.0029 0.0087 0.0101
Echinococcus granulosus nuclear factor of activated T cells 5 0.0074 0.0363 0.0428
Loa Loa (eye worm) melatonin receptor type 1A 0.07 0.4137 0.4893
Entamoeba histolytica fructose-1,6-bisphosphate aldolase, putative 0.0308 0.1774 1
Brugia malayi hypothetical protein 0.002 0.0033 0.0037
Loa Loa (eye worm) hypothetical protein 0.07 0.4137 0.4893
Toxoplasma gondii hypothetical protein 0.0029 0.0087 0.0299
Trypanosoma brucei cytochrome P450, putative 0.0046 0.0193 0.0715
Entamoeba histolytica hypothetical protein 0.0071 0.0344 0.1673
Echinococcus granulosus rhodopsin orphan GPCR 0.07 0.4137 0.4893
Brugia malayi GTP-binding regulatory protein Gs alpha-S chain, putative 0.0232 0.1314 0.1552
Plasmodium vivax hypothetical protein, conserved 0.004 0.0155 0.0607
Brugia malayi Cytochrome P450 family protein 0.0046 0.0193 0.0226
Echinococcus granulosus o acyltransferase membrane bound domain 0.0049 0.0207 0.0243
Brugia malayi hypothetical protein 0.07 0.4137 0.4893
Trypanosoma cruzi DNA polymerase beta thumb, putative 0.0045 0.0188 0.073
Echinococcus multilocularis serotonin receptor 0.07 0.4137 0.4136
Schistosoma mansoni sodium/chloride dependent transporter 0.003 0.0093 0.0107
Toxoplasma gondii LsmAD domain-containing protein 0.0053 0.0231 0.0867
Entamoeba histolytica deoxycytidyl transferase, putative 0.0038 0.0145 0.0516
Echinococcus granulosus 5'partial|histone lysine N methyltransferase SETDB2 0.0151 0.0826 0.0975
Trypanosoma cruzi myo-inositol-1(or 4)-monophosphatase 1, putative 0.0037 0.0136 0.0525
Loa Loa (eye worm) hypothetical protein 0.0016 0.0011 0.0011
Echinococcus granulosus single minded 2 0.0039 0.0148 0.0173
Schistosoma mansoni biogenic amine receptor 0.07 0.4137 0.4893
Treponema pallidum alginate O-acetylation protein (algI) 0.0049 0.0207 0.0679
Loa Loa (eye worm) jmjC domain-containing protein 0.0016 0.0011 0.0011
Brugia malayi putative neuropeptide receptor 0.07 0.4137 0.4893
Echinococcus granulosus mitogen activated protein kinase 0.0102 0.0531 0.0626
Trichomonas vaginalis high-affinity cGMP-specific 3,5-cyclic phosphodiesterase, putative 0.0074 0.036 0.0462
Schistosoma mansoni lamin 0.0056 0.0254 0.0298
Brugia malayi Serotonin receptor 0.07 0.4137 0.4893
Trypanosoma brucei DNA polymerase kappa, putative 0.0044 0.018 0.0664
Echinococcus granulosus sodium dependent neurotransmitter transporter 0.0029 0.0087 0.0101
Trichomonas vaginalis cGMP-inhibited 3,5-cyclic phosphodiesterase, putative 0.0074 0.036 0.0462
Trichomonas vaginalis ran, putative 0.0024 0.0057 0.0053
Mycobacterium tuberculosis Possible cytochrome P450 135A1 Cyp135A1 0.0028 0.0086 0.0478
Echinococcus granulosus aldehyde dehydrogenase mitochondrial 0.0122 0.0653 0.077
Schistosoma mansoni hypothetical protein 0.0016 0.001 0.0009
Schistosoma mansoni hypothetical protein 0.07 0.4137 0.4893
Echinococcus granulosus alpha 1A adrenergic receptor 0.07 0.4137 0.4893
Entamoeba histolytica vacuolar protein sorting 26 0.0049 0.0207 0.0877
Loa Loa (eye worm) hypothetical protein 0.07 0.4137 0.4893
Schistosoma mansoni retinoblastoma-binding protein 4 (rbbp4) 0.0015 0.0003 0.0001
Loa Loa (eye worm) PDE1B protein 0.1415 0.8454 1
Toxoplasma gondii hypothetical protein 0.011 0.0577 0.2226
Loa Loa (eye worm) doublecortin family protein 0.002 0.0033 0.0037
Trichomonas vaginalis conserved hypothetical protein 0.0074 0.036 0.0462
Trichomonas vaginalis set domain proteins, putative 0.1244 0.7423 1
Mycobacterium tuberculosis Two component sensor histidine kinase DosT 0.004 0.0155 0.0953
Brugia malayi Protein kinase domain containing protein 0.0015 0.0008 0.0007
Echinococcus granulosus diacylglycerol O acyltransferase 1 0.0049 0.0207 0.0243
Echinococcus multilocularis lysine specific demethylase 5A 0.006 0.0277 0.0275
Schistosoma mansoni rhodopsin-like orphan GPCR 0.07 0.4137 0.4893
Echinococcus granulosus fmrfamide receptor 0.07 0.4137 0.4893
Trichomonas vaginalis cGMP-dependent 3,5-cyclic phosphodiesterase, putative 0.0184 0.1023 0.1357
Echinococcus multilocularis dna polymerase eta 0.0038 0.0145 0.0143
Loa Loa (eye worm) hypothetical protein 0.005 0.0216 0.0253
Mycobacterium ulcerans aldehyde dehydrogenase 0.0122 0.0653 0.6637
Brugia malayi hypothetical protein 0.07 0.4137 0.4893
Trichomonas vaginalis porcupine, putative 0.0049 0.0207 0.0256
Plasmodium falciparum histone acetyltransferase GCN5 0.008 0.0398 1
Leishmania major glycerol uptake protein, putative 0.0049 0.0207 0.0805
Echinococcus multilocularis high affinity cAMP specific 3',5' cyclic 0.0074 0.036 0.0358
Schistosoma mansoni alpha-1 adrenergic receptor 0.07 0.4137 0.4893
Echinococcus multilocularis calcium:calmodulin dependent 3',5' cyclic 0.0437 0.2553 0.2551
Brugia malayi hypothetical protein 0.07 0.4137 0.4893
Loa Loa (eye worm) hypothetical protein 0.0029 0.0087 0.0101
Schistosoma mansoni histamine h1 receptor 0.07 0.4137 0.4893
Schistosoma mansoni biogenic amine (dopamine) receptor 0.07 0.4137 0.4893
Schistosoma mansoni sodium-dependent neurotransmitter transporter 0.0029 0.0087 0.0101
Toxoplasma gondii 3'5'-cyclic nucleotide phosphodiesterase domain-containing protein 0.0074 0.036 0.1372
Brugia malayi 6-phosphofructokinase 0.011 0.0577 0.068
Trichomonas vaginalis rod cGMP-specific 3,5-cyclic phosphodiesterase, putative 0.0184 0.1023 0.1357
Trichomonas vaginalis cAMP-specific phosphodiesterase, putative 0.0184 0.1023 0.1357
Schistosoma mansoni inositol monophosphatase 0.0037 0.0136 0.0159
Toxoplasma gondii 3'5'-cyclic nucleotide phosphodiesterase domain-containing protein 0.0074 0.036 0.1372
Brugia malayi Probable 3',5'-cyclic phosphodiesterase R153.1, putative 0.0074 0.036 0.0424
Leishmania major myo-inositol-1(or 4)-monophosphatase 1, putative 0.0037 0.0136 0.0525
Echinococcus granulosus geminin 0.0349 0.2022 0.239
Mycobacterium tuberculosis Probable cytochrome P450 125 Cyp125 0.0028 0.0086 0.0478
Loa Loa (eye worm) MBOAT family protein 0.0049 0.0207 0.0243
Loa Loa (eye worm) MBOAT family protein 0.0049 0.0207 0.0243
Giardia lamblia hypothetical protein 0.0074 0.036 0.1766
Loa Loa (eye worm) GTP-binding nuclear protein RAN/TC4 0.0024 0.0057 0.0065
Toxoplasma gondii 3'5'-cyclic nucleotide phosphodiesterase domain-containing protein 0.0074 0.036 0.1372
Toxoplasma gondii Sodium:neurotransmitter symporter family protein 0.0029 0.0087 0.0299
Schistosoma mansoni camp-specific cyclic nucleotide phosphodiesterase 0.0074 0.036 0.0424
Trypanosoma brucei DNA polymerase beta thumb, putative 0.0045 0.0188 0.0697
Schistosoma mansoni aryl hydrocarbon receptor 0.0052 0.0231 0.0271
Trypanosoma brucei cAMP phosphodiesterase A, putative 0.0437 0.2553 1
Echinococcus multilocularis NADP dependent isocitrate dehydrogenase 0.0017 0.0016 0.0014
Loa Loa (eye worm) solute carrier family 6 member 4 0.0169 0.0932 0.1101
Brugia malayi Pre-SET motif family protein 0.0157 0.0861 0.1016
Echinococcus granulosus lysine specific demethylase 5A 0.006 0.0277 0.0326
Echinococcus multilocularis aldehyde dehydrogenase, mitochondrial 0.0122 0.0653 0.0651
Plasmodium falciparum 3',5'-cyclic nucleotide phosphodiesterase, putative 0.0074 0.036 0.9008
Trichomonas vaginalis 6-phosphofructokinase, putative 0.003 0.0093 0.0102
Schistosoma mansoni neuropeptide receptor 0.07 0.4137 0.4893
Schistosoma mansoni peptide (FMRFamide/somatostatin)-like receptor 0.07 0.4137 0.4893
Plasmodium falciparum ATP-dependent 6-phosphofructokinase 0.003 0.0093 0.2123
Trypanosoma brucei DNA polymerase kappa, putative 0.007 0.0339 0.1291
Trypanosoma brucei DNA polymerase kappa, putative 0.007 0.0339 0.1291
Toxoplasma gondii hypothetical protein 0.0029 0.0087 0.0299
Schistosoma mansoni peptide (FMRFamide/neurokinin-3)-like receptor 0.07 0.4137 0.4893
Schistosoma mansoni histone-lysine n-methyltransferase setb1 0.0157 0.0861 0.1016
Echinococcus granulosus importin subunit beta 1 0.0032 0.0108 0.0125
Brugia malayi intermediate filament protein 0.0056 0.0254 0.0298
Echinococcus granulosus JmjC domain containing protein 4 0.0016 0.0011 0.0011
Schistosoma mansoni jumonji/arid domain-containing protein 0.006 0.0277 0.0326
Toxoplasma gondii histone lysine acetyltransferase GCN5-B 0.0087 0.0442 0.1697
Echinococcus granulosus arachidonate 5 lipoxygenase 0.0055 0.0246 0.0289
Schistosoma mansoni calcium/calmodulin-dependent 35-cyclic nucleotide phosphodiesterase 0.1415 0.8454 1
Onchocerca volvulus 0.07 0.4137 0.5572
Echinococcus granulosus GPCR family 2 0.0016 0.001 0.0009
Plasmodium falciparum amino acid transporter, putative 0.0029 0.0087 0.1962
Toxoplasma gondii 3'5'-cyclic nucleotide phosphodiesterase domain-containing protein 0.0074 0.036 0.1372
Echinococcus granulosus microtubule associated protein 2 0.0705 0.4171 0.4933
Echinococcus multilocularis G-protein coupled receptor, putative 0.07 0.4137 0.4136
Loa Loa (eye worm) hypothetical protein 0.002 0.0033 0.0037
Leishmania major GTP-binding protein, putative 0.0024 0.0057 0.0214
Mycobacterium tuberculosis Conserved protein 0.004 0.0158 0.0975
Schistosoma mansoni aldehyde dehydrogenase 0.0122 0.0653 0.077
Leishmania major cytochrome p450-like protein 0.0028 0.0086 0.0328
Trypanosoma cruzi Lanosterol 14-alpha demethylase 0.0028 0.0086 0.0328
Trypanosoma cruzi hypothetical protein, conserved 0.0074 0.036 0.1403
Trichomonas vaginalis conserved hypothetical protein 0.011 0.0577 0.0755
Leishmania major DNA polymerase kappa, putative 0.0046 0.0193 0.075
Onchocerca volvulus 0.07 0.4137 0.5572
Loa Loa (eye worm) beta-lactamase 0.004 0.0158 0.0185
Schistosoma mansoni sodium-dependent amino acid transporter 0.0029 0.0087 0.0101
Brugia malayi RNA, U transporter 1 0.0091 0.0465 0.0548
Schistosoma mansoni Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) 0.0232 0.1314 0.1552
Mycobacterium ulcerans DNA polymerase IV 0.007 0.0339 0.2965
Trichomonas vaginalis conserved hypothetical protein 0.0049 0.0207 0.0256
Leishmania major lanosterol 14-alpha-demethylase, putative 0.0028 0.0086 0.0328
Plasmodium vivax 6-phosphofructokinase, putative 0.003 0.0093 0.0366
Mycobacterium tuberculosis Cytochrome P450 121 Cyp121 0.0028 0.0086 0.0478
Echinococcus granulosus rhodopsin orphan GPCR 0.07 0.4137 0.4893
Brugia malayi jmjC domain containing protein 0.0016 0.0011 0.0011
Leishmania major DNA polymerase eta, putative 0.0038 0.0145 0.0561
Onchocerca volvulus 0.0029 0.0087 0.0115
Echinococcus granulosus g protein linked acetylcholine receptor gar 2a 0.07 0.4137 0.4893
Brugia malayi Sodium:neurotransmitter symporter family protein 0.0029 0.0087 0.0101
Trichomonas vaginalis phosphofructokinase, putative 0.003 0.0093 0.0102
Trichomonas vaginalis calcium/calmodulin-dependent 3,5-cyclic nucleotide phosphodiesterase, putative 0.0184 0.1023 0.1357
Echinococcus multilocularis rhodopsin orphan GPCR 0.07 0.4137 0.4136
Trichomonas vaginalis myo inositol monophosphatase, putative 0.0037 0.0136 0.016
Schistosoma mansoni biogenic amine (octopamine/dopamine) receptor 0.07 0.4137 0.4893
Mycobacterium tuberculosis Probable esterase/lipase LipP 0.004 0.0158 0.0975
Trypanosoma cruzi hypothetical protein, conserved 0.004 0.0158 0.0612
Echinococcus multilocularis neuropeptide receptor A26 0.07 0.4137 0.4136
Echinococcus multilocularis fmrfamide receptor 0.07 0.4137 0.4136
Schistosoma mansoni peptide (FMRFamide/somatostatin)-like receptor 0.07 0.4137 0.4893
Echinococcus multilocularis Jumonji, AT rich interactive domain 1B 0.0016 0.0011 0.0009
Brugia malayi Dopamine receptor 0.07 0.4137 0.4893
Loa Loa (eye worm) hypothetical protein 0.07 0.4137 0.4893
Schistosoma mansoni neuropeptide receptor 0.07 0.4137 0.4893
Mycobacterium tuberculosis Probable cytochrome P450 137 Cyp137 0.0028 0.0086 0.0478
Echinococcus multilocularis arachidonate 5 lipoxygenase 0.0055 0.0246 0.0244
Brugia malayi G-protein coupled receptor 0.07 0.4137 0.4893
Schistosoma mansoni hypothetical protein 0.0034 0.012 0.014
Trichomonas vaginalis Importin beta-1 subunit, putative 0.0026 0.0071 0.0072
Trypanosoma cruzi cAMP specific phosphodiesterase, putative 0.0184 0.1023 0.4
Echinococcus granulosus neuropeptides capa receptor 0.07 0.4137 0.4893
Brugia malayi Tachykinin-like peptides receptor 99D 0.07 0.4137 0.4893
Echinococcus multilocularis tm gpcr rhodopsin gpcr rhodopsin superfamily 0.07 0.4137 0.4136
Onchocerca volvulus Adenylate cyclase type 2 homolog 0.0083 0.0416 0.0558
Loa Loa (eye worm) hypothetical protein 0.07 0.4137 0.4893
Loa Loa (eye worm) hypothetical protein 0.0026 0.0072 0.0083
Brugia malayi jmjC domain containing protein 0.006 0.0277 0.0326
Trichomonas vaginalis calcium/calmodulin-dependent 3,5-cyclic nucleotide phosphodiesterase, putative 0.0184 0.1023 0.1357
Leishmania major hypothetical protein, conserved 0.004 0.0158 0.0612
Echinococcus multilocularis mitogen activated protein kinase 3 0.0102 0.0531 0.0529
Mycobacterium tuberculosis Probable aldehyde dehydrogenase 0.0122 0.0653 0.4372
Toxoplasma gondii hypothetical protein 0.0052 0.0229 0.0855
Trypanosoma brucei DNA polymerase kappa, putative 0.0046 0.0193 0.0717
Loa Loa (eye worm) hypothetical protein 0.0157 0.0861 0.1016
Loa Loa (eye worm) RecQ helicase 0.0021 0.0041 0.0046
Brugia malayi Probable 3',5'-cyclic phosphodiesterase T04D3.3, putative 0.1415 0.8454 1
Schistosoma mansoni norepinephrine/norepinephrine transporter 0.0029 0.0087 0.0101
Echinococcus multilocularis gcn5proteinral control of amino acid synthesis 0.0297 0.171 0.1708
Schistosoma mansoni loxhd1 0.002 0.0033 0.0037
Mycobacterium tuberculosis Possible cytochrome P450 126 Cyp126 0.0028 0.0086 0.0478
Echinococcus multilocularis neuropeptide s receptor 0.07 0.4137 0.4136
Echinococcus granulosus Basic leucine zipper bZIP transcription 0.0071 0.0344 0.0405
Plasmodium vivax histone acetyltransferase GCN5, putative 0.0087 0.0442 0.1733
Brugia malayi Doublecortin family protein 0.002 0.0033 0.0037
Echinococcus granulosus rhodopsin orphan GPCR 0.07 0.4137 0.4893
Onchocerca volvulus Adenylate cyclase type 3 homolog 0.0083 0.0416 0.0558
Loa Loa (eye worm) hypothetical protein 0.07 0.4137 0.4893
Echinococcus multilocularis jumonji domain containing 1A 0.0016 0.0011 0.0009
Loa Loa (eye worm) hypothetical protein 0.0449 0.2622 0.31
Echinococcus multilocularis rhodopsin orphan GPCR 0.07 0.4137 0.4136
Trichomonas vaginalis high-affinity cGMP-specific 3,5-cyclic phosphodiesterase, putative 0.0074 0.036 0.0462
Echinococcus multilocularis phd:f box containing protein 0.0016 0.0011 0.0009
Loa Loa (eye worm) 6-phosphofructokinase 0.011 0.0577 0.068
Loa Loa (eye worm) hypothetical protein 0.0026 0.0072 0.0083
Echinococcus granulosus allatostatin A receptor 0.07 0.4137 0.4893
Trypanosoma cruzi glycerol uptake protein, putative 0.0049 0.0207 0.0805
Trypanosoma cruzi isocitrate dehydrogenase, putative 0.0017 0.0016 0.0055
Echinococcus multilocularis Ankyrin 0.0015 0.0003 0.0001
Leishmania major hypothetical protein, conserved 0.0074 0.036 0.1403
Brugia malayi RE15519p 0.07 0.4137 0.4893
Echinococcus granulosus intermediate filament protein 0.0056 0.0254 0.0298
Schistosoma mansoni family S12 unassigned peptidase (S12 family) 0.004 0.0158 0.0185
Onchocerca volvulus 0.07 0.4137 0.5572
Schistosoma mansoni camp-specific 35-cyclic phosphodiesterase 0.0074 0.036 0.0424
Mycobacterium tuberculosis Probable lipase LipE 0.004 0.0158 0.0975
Brugia malayi cytochrome P450 0.0028 0.0086 0.0099

Activities

Activity type Activity value Assay description Source Reference
Relative binding (binding) = 0.0002 % Relative binding by measuring competition for glucagon receptor between [125]glucagon and the compound. ChEMBL. 11311060
Relative binding (binding) = 0.0002 % Relative binding by measuring competition for glucagon receptor between [125]glucagon and the compound. ChEMBL. 11311060
Relative potency (binding) = 0.0002 % Relative potency was evaluated by measuring potency for conversion of [alpha-32P]ATP to cyclic 3',5'-AMP relative to glucagon ChEMBL. 11311060
Relative potency (binding) = 0.0002 % Relative potency was evaluated by measuring potency for conversion of [alpha-32P]ATP to cyclic 3',5'-AMP relative to glucagon ChEMBL. 11311060

Phenotypes

Whole-cell/tissue/organism interactions

We have no records of whole-cell/tissue assays done with this compound What does this mean?

Many chemical entities in TDR Targets come from high-throughput screenings with whole cells or tissue samples, and not all assayed compounds have been tested against a single a single target protein, probably because they get ruled out during screening process. Even if these compounds may have not been of interest in the original screening, they may come as interesting leads for other screening assays. Furthermore, we may be able to propose drug-target associations using chemical similarities and network patterns.

Annotated phenotypes:

We have no manually annotated phenotypes for this drug. What does this mean? / Care to help?
In TDR Targets, information about phenotypes that are caused by drugs, or by genetic manipulation of cells (e.g. gene knockouts or knockdowns) is manually curated from the literature. These descriptions help to describe the potential of the target for drug development. If no information is available for this gene or if the information is incomplete, this may mean that i) the papers containing this information either appeared after the curation effort for this organism was carried out or they were inadvertently missed by curators; or that ii) the curation effort for this organism has not yet started.
 
In any case, if you have information about papers containing relevant validation data for this target, please log in using your TDR Targets username and password and send them to us using the corresponding form in this page (only visible to registered users) or contact us.

External resources for this compound

Bibliographic References

1 literature reference was collected for this gene.

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