Detailed information for compound 433725

Basic information

Technical information
  • TDR Targets ID: 433725
  • Name: tert-butyl (NZ)-N-[[4-[4-[[(Z)-N,N'-bis[(2-me thylpropan-2-yl)oxycarbonyl]carbamimidoyl]ami no]phenoxy]anilino]-[(2-methylpropan-2-yl)oxy carbonylamino]methylidene]carbamate
  • MW: 684.78 | Formula: C34H48N6O9
  • H donors: 4 H acceptors: 4 LogP: 7.8 Rotable bonds: 20
    Rule of 5 violations (Lipinski): 2
  • SMILES: O=C(OC(C)(C)C)N/C(=N/C(=O)OC(C)(C)C)/Nc1ccc(cc1)Oc1ccc(cc1)N/C(=N/C(=O)OC(C)(C)C)/NC(=O)OC(C)(C)C
  • InChi: 1S/C34H48N6O9/c1-31(2,3)46-27(41)37-25(38-28(42)47-32(4,5)6)35-21-13-17-23(18-14-21)45-24-19-15-22(16-20-24)36-26(39-29(43)48-33(7,8)9)40-30(44)49-34(10,11)12/h13-20H,1-12H3,(H2,35,37,38,41,42)(H2,36,39,40,43,44)
  • InChiKey: SXMKKNAKLQELNQ-UHFFFAOYSA-N  


Substructure search Similarity search

Network

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Synonyms

  • tert-butyl (NZ)-N-[[4-[4-[[(Z)-N,N'-bis(tert-butoxycarbonyl)carbamimidoyl]amino]phenoxy]anilino]-(tert-butoxycarbonylamino)methylene]carbamate
  • (NZ)-N-[[[tert-butoxy(oxo)methyl]amino]-[4-[4-[[(Z)-[[tert-butoxy(oxo)methyl]amino]-[tert-butoxy(oxo)methyl]iminomethyl]amino]phenoxy]anilino]methylene]carbamic acid tert-butyl ester
  • tert-butyl (NZ)-N-[[[4-[4-[[(Z)-N,N'-bis[(2-methylpropan-2-yl)oxycarbonyl]carbamimidoyl]amino]phenoxy]phenyl]amino]-[(2-methylpropan-2-yl)oxycarbonylamino]methylidene]carbamate
  • (NZ)-N-[[4-[4-[[(Z)-N,N'-bis(tert-butoxycarbonyl)amidino]amino]phenoxy]anilino]-(tert-butoxycarbonylamino)methylene]carbamic acid tert-butyl ester

Targets

Known targets for this compound

No curated genes were found associated with this compound

Predicted pathogen targets for this compound

By orthology
No druggable targets predicted by orthology data
By sequence similarity to non orthologous known druggable targets
No druggable targets predicted by sequence similarity
Obtained from network model

Ranking Plot

Putative Targets List

Species Potential target Raw Global Species
Trichomonas vaginalis abcb9, putative 0.014 0.0146 0.1431
Plasmodium falciparum major facilitator superfamily domain-containing protein, putative 0.0015 0.0008 0.0152
Loa Loa (eye worm) ATP-binding cassette sub-family B member 2 0.014 0.0146 0.1431
Toxoplasma gondii ABC transporter transmembrane region domain-containing protein 0.0044 0.004 0.0386
Plasmodium falciparum mitogen-activated protein kinase 2 0.0168 0.0176 0.3692
Schistosoma mansoni dep domain containing protein 0.001 0.0003 0.0032
Schistosoma mansoni Tr4/Tr2 (homologue) 0.001 0.0003 0.003
Trichomonas vaginalis ATP-binding cassette transporter, putative 0.014 0.0146 0.1431
Toxoplasma gondii histone lysine demethylase JMJD6a 0.0009 0.0002 0.0015
Mycobacterium tuberculosis Probable transmembrane multidrug efflux pump 0.014 0.0146 0.5139
Schistosoma mansoni inositol monophosphatase 0.0037 0.0032 0.0318
Leishmania major hypothetical protein, conserved 0.3354 0.3667 1
Onchocerca volvulus 0.0008 0.0001 0.0033
Schistosoma mansoni phosphatidylinositol-45-bisphosphate 3-kinase catalytic subunit alpha PI3K 0.018 0.0189 0.1861
Trypanosoma cruzi hexose transporter, putative 0.0032 0.0027 0.0079
Trypanosoma cruzi phosphatidylinositol 4-kinase alpha, putative 0.018 0.0189 0.0546
Plasmodium vivax hypothetical protein, conserved 0.0042 0.0038 0.0774
Schistosoma mansoni inositol monophosphatase 0.0037 0.0032 0.0318
Toxoplasma gondii lysine-tRNA ligase 0.0023 0.0017 0.0163
Loa Loa (eye worm) hypothetical protein 0.001 0.0003 0.003
Entamoeba histolytica hypothetical protein 0.018 0.0189 0.1861
Echinococcus granulosus phd:f box containing protein 0.0009 0.0002 0.0002
Trypanosoma cruzi prolyl-tRNA synthetase, putative 0.0036 0.0032 0.0092
Entamoeba histolytica hypothetical protein 0.018 0.0189 0.1861
Giardia lamblia Phosphoinositide-3-kinase, catalytic, alpha polypeptide 0.018 0.0189 0.1796
Trichomonas vaginalis conserved hypothetical protein 0.0015 0.0008 0.0079
Trichomonas vaginalis lipid A export ATP-binding/permease protein msba, putative 0.0044 0.004 0.0394
Brugia malayi Phosphatidylinositol 3- and 4-kinase family protein 0.018 0.0189 0.1861
Entamoeba histolytica protein kinase, putative 0.0032 0.0027 0.0264
Schistosoma mansoni glucose transport protein 0.0104 0.0106 0.1039
Schistosoma mansoni polycystin 1-related 0.0023 0.0017 0.0165
Trichomonas vaginalis sugar transporter, putative 0.0015 0.0008 0.0079
Plasmodium falciparum phd finger protein, putative 0.0029 0.0024 0.0486
Echinococcus multilocularis Phosphatidylinositol 4 kinase type 2 beta 0.018 0.0189 0.0189
Entamoeba histolytica protein kinase rad3, putative 0.0528 0.0571 0.5606
Echinococcus multilocularis solute carrier family 2, facilitated glucose 0.0104 0.0106 0.0106
Mycobacterium leprae PROBABLE DRUGS-TRANSPORT TRANSMEMBRANE ATP-BINDING PROTEIN ABC TRANSPORTER 0.0044 0.004 0.2083
Echinococcus granulosus regulator of G protein signaling 7 0.001 0.0003 0.0003
Loa Loa (eye worm) hypothetical protein 0.0015 0.0008 0.0079
Echinococcus granulosus lipoxygenase domain containing protein 0.0023 0.0017 0.0017
Loa Loa (eye worm) hypothetical protein 0.0015 0.0008 0.0079
Trichomonas vaginalis phosphatidylinositol 3-kinase class, putative 0.018 0.0189 0.1861
Brugia malayi Pre-SET motif family protein 0.0207 0.0219 0.2155
Brugia malayi AMP-binding enzyme family protein 0.0027 0.0022 0.0216
Toxoplasma gondii phosphatidylinositol 3- and 4-kinase 0.018 0.0189 0.1854
Loa Loa (eye worm) hypothetical protein 0.0015 0.0008 0.0079
Wolbachia endosymbiont of Brugia malayi fructose-1,6-bisphosphatase 0.0037 0.0032 0.7587
Echinococcus granulosus ecdysone induced protein 78C 0.001 0.0003 0.0003
Leishmania major glucose transporter, lmgt1 0.0032 0.0027 0.0072
Schistosoma mansoni sugar transporter 0.0015 0.0008 0.0079
Mycobacterium leprae PROBABLE FATTY-ACID-CoA LIGASE FADD2 (FATTY-ACID-CoA SYNTHETASE) (FATTY-ACID-CoA SYNTHASE) 0.0027 0.0022 0.1122
Mycobacterium tuberculosis Lysyl-tRNA synthetase 1 LysS (lysine--tRNA ligase 1) (LysRS 1) (lysine translase) 0.002 0.0014 0.0453
Brugia malayi ABC transporter transmembrane region family protein 0.0042 0.0038 0.0378
Echinococcus multilocularis phosphatidylinositol 4,5 bisphosphate 3 kinase 0.018 0.0189 0.0189
Brugia malayi Bromodomain containing protein 0.0033 0.0028 0.0278
Entamoeba histolytica hypothetical protein 0.0041 0.0037 0.0366
Brugia malayi Phosphatidylinositol 3- and 4-kinase family protein 0.0937 0.1018 1
Onchocerca volvulus 0.0015 0.0008 0.032
Trypanosoma brucei inositol-1(or 4)-monophosphatase 1, putative 0.0037 0.0032 0.031
Trichomonas vaginalis PIKK family atypical protein kinase 0.0528 0.0571 0.5606
Leishmania major phosphatidylinositol 4-kinase alpha, putative 0.018 0.0189 0.0515
Onchocerca volvulus 0.0048 0.0045 0.1783
Schistosoma mansoni lysyl-tRNA synthetase 0.0023 0.0017 0.0171
Schistosoma mansoni acetyl-CoA synthetase 0.0008 0.0001 0.0008
Trichomonas vaginalis sugar transporter, putative 0.0015 0.0008 0.0079
Loa Loa (eye worm) hypothetical protein 0.0042 0.0038 0.0369
Trypanosoma brucei glucose transporter 1E 0.0032 0.0027 0.026
Schistosoma mansoni protein kinase 0.0032 0.0027 0.0264
Plasmodium falciparum conserved Plasmodium membrane protein, unknown function 0.0009 0.0002 0.0034
Echinococcus multilocularis segment polarity protein dishevelled 0.001 0.0003 0.0003
Trypanosoma brucei bifunctional aminoacyl-tRNA synthetase, putative 0.0036 0.0032 0.0305
Mycobacterium tuberculosis Probable fatty-acid-CoA ligase FadD2 (fatty-acid-CoA synthetase) (fatty-acid-CoA synthase) 0.0027 0.0022 0.0751
Brugia malayi Sugar transporter family protein 0.0104 0.0106 0.1039
Entamoeba histolytica phosphatidylinositol 3-kinase, putative 0.018 0.0189 0.1861
Brugia malayi ABC transporter 0.0042 0.0038 0.0378
Schistosoma mansoni rab6-interacting 0.0023 0.0017 0.0165
Leishmania major myo-inositol-1(or 4)-monophosphatase 1, putative 0.0037 0.0032 0.0086
Brugia malayi oxidoreductase, short chain dehydrogenase/reductase family protein 0.0008 0.0001 0.0008
Trichomonas vaginalis PIKK family atypical protein kinase 0.0937 0.1018 1
Schistosoma mansoni ubiquitously transcribed sex (X/Y) chromosome tetratricopeptide repeat protein-related 0.0009 0.0002 0.0023
Brugia malayi Nuclear hormone receptor family member nhr-40 0.001 0.0003 0.003
Trichomonas vaginalis myo inositol monophosphatase, putative 0.0037 0.0032 0.0318
Plasmodium vivax acyl-CoA synthetase, putative 0.002 0.0014 0.0287
Echinococcus multilocularis solute carrier family 22 0.0015 0.0008 0.0008
Echinococcus multilocularis guanine nucleotide binding protein G(s) subunit 0.0053 0.005 0.005
Leishmania major glucose transporter/membrane transporter D2, putative 0.0032 0.0027 0.0072
Toxoplasma gondii phosphatidylinositol 3- and 4-kinase 0.018 0.0189 0.1854
Trichomonas vaginalis PIKK family atypical protein kinase 0.0528 0.0571 0.5606
Trypanosoma brucei PHD-zinc-finger like domain containing protein, putative 0.0009 0.0002 0.0016
Echinococcus granulosus RUN 0.0023 0.0017 0.0017
Brugia malayi AMP-binding enzyme family protein 0.0008 0.0001 0.0008
Giardia lamblia Multidrug resistance-associated protein Mrp2 0.0042 0.0038 0.0301
Schistosoma mansoni nuclear hormone receptor nor-1/nor-2 0.001 0.0003 0.003
Leishmania major 4-coumarate:coa ligase-like protein 0.0027 0.0022 0.0058
Trichomonas vaginalis PIKK family atypical protein kinase 0.0937 0.1018 1
Mycobacterium tuberculosis Probable fatty-acid-CoA ligase FadD7 (fatty-acid-CoA synthetase) (fatty-acid-CoA synthase) 0.0019 0.0013 0.0439
Trichomonas vaginalis PIKK family atypical protein kinase 0.0937 0.1018 1
Schistosoma mansoni RAR-like nuclear receptor 0.001 0.0003 0.003
Schistosoma mansoni thyroid hormone receptor 0.001 0.0003 0.003
Plasmodium vivax mitogen-activated protein kinase 2, putative 0.0168 0.0176 0.3692
Entamoeba histolytica P-glycoprotein-2 0.014 0.0146 0.1431
Plasmodium vivax multidrug resistance-associated protein 2, putative 0.0044 0.004 0.0829
Trichomonas vaginalis conserved hypothetical protein 0.0348 0.0373 0.3667
Loa Loa (eye worm) hypothetical protein 0.0042 0.0038 0.0369
Trichomonas vaginalis sugar transporter, putative 0.0032 0.0027 0.0268
Brugia malayi MH2 domain containing protein 0.0008 0.0001 0.0009
Trichomonas vaginalis PIKK family atypical protein kinase 0.0528 0.0571 0.5606
Loa Loa (eye worm) hypothetical protein 0.001 0.0003 0.0032
Echinococcus granulosus General substrate transporter 0.0089 0.009 0.009
Echinococcus multilocularis multidrug resistance protein 1 0.014 0.0146 0.0146
Trichomonas vaginalis sugar transporter, putative 0.0015 0.0008 0.0079
Toxoplasma gondii sugar transporter ST2 0.0015 0.0008 0.0071
Loa Loa (eye worm) hypothetical protein 0.001 0.0003 0.003
Echinococcus multilocularis calcium:calmodulin dependent protein kinase type 0.0032 0.0027 0.0027
Trichomonas vaginalis sugar transporter, putative 0.0015 0.0008 0.0079
Plasmodium vivax multidrug resistance-associated protein 1, putative 0.0044 0.004 0.0829
Trypanosoma brucei glucose transporter, putative 0.0032 0.0027 0.026
Schistosoma mansoni hypothetical protein 0.0029 0.0024 0.0235
Brugia malayi multidrug resistance related protein 1 0.0044 0.004 0.0394
Leishmania major hypothetical protein, unknown function 0.018 0.0189 0.0515
Trypanosoma brucei phosphatidylinositol 4-kinase, putative 0.0937 0.1018 1
Trichomonas vaginalis sugar transporter, putative 0.0032 0.0027 0.0268
Brugia malayi Phosphatidylinositol 3- and 4-kinase family protein 0.018 0.0189 0.1861
Schistosoma mansoni jumonji domain containing protein 0.0009 0.0002 0.0023
Plasmodium falciparum lysine--tRNA ligase 0.0023 0.0017 0.035
Echinococcus multilocularis nuclear receptor 2DBD gamma 0.001 0.0003 0.0003
Entamoeba histolytica phosphatidylinositol 3-kinase, putative 0.018 0.0189 0.1861
Trypanosoma brucei phosphatidylinositol 3-kinase catalytic subunit, putative 0.018 0.0189 0.1854
Toxoplasma gondii ABC transporter transmembrane region domain-containing protein 0.0044 0.004 0.0386
Trypanosoma cruzi lysyl-tRNA synthetase, putative 0.0023 0.0017 0.005
Entamoeba histolytica protein kinase, putative 0.0032 0.0027 0.0264
Toxoplasma gondii ABC transporter transmembrane region domain-containing protein 0.0044 0.004 0.0386
Brugia malayi jmjC domain containing protein 0.0009 0.0002 0.0023
Echinococcus granulosus synaptic vesicle 2 protein 0.0015 0.0008 0.0008
Toxoplasma gondii calcium-dependent protein kinase CDPK3 0.0032 0.0027 0.0256
Trichomonas vaginalis prolyl-tRNA synthetase, putative 0.0031 0.0026 0.0257
Loa Loa (eye worm) inositol-1 0.0037 0.0032 0.0318
Giardia lamblia Histone acetyltransferase GCN5 0.0045 0.0041 0.0328
Trichomonas vaginalis lipid A export ATP-binding/permease protein msba, putative 0.014 0.0146 0.1431
Toxoplasma gondii FATC domain-containing protein 0.0775 0.0841 0.8256
Trypanosoma brucei myo-inositol/proton symporter (MIT) 0.0015 0.0008 0.0071
Schistosoma mansoni sugar transporter 0.0015 0.0008 0.0079
Loa Loa (eye worm) CAMK/CAMK2 protein kinase 0.0032 0.0027 0.0264
Mycobacterium ulcerans transmembrane ABC transporter ATP-binding protein 0.0044 0.004 1
Mycobacterium ulcerans hypothetical protein 0.0042 0.0038 0.9345
Entamoeba histolytica acyl-CoA synthetase, putative 0.0027 0.0022 0.0216
Mycobacterium ulcerans acyl-CoA synthetase 0.0027 0.0022 0.5388
Schistosoma mansoni phosphatidylinositol 4-kinase type-II 0.018 0.0189 0.1861
Echinococcus multilocularis ATP binding cassette subfamily B (MDR:TAP) 0.014 0.0146 0.0146
Plasmodium vivax calcium-dependent protein kinase 4, putative 0.0032 0.0027 0.055
Trichomonas vaginalis myo inositol monophosphatase, putative 0.0037 0.0032 0.0318
Schistosoma mansoni protein kinase 0.0032 0.0027 0.0264
Schistosoma mansoni multidrug resistance protein 0.014 0.0146 0.1431
Schistosoma mansoni multidrug resistance protein 0.0044 0.004 0.0394
Loa Loa (eye worm) hypothetical protein 0.0015 0.0008 0.0079
Echinococcus multilocularis PHD finger protein rhinoceros 0.0029 0.0024 0.0024
Trypanosoma brucei ABC transporter of the mitochondrion, putative 0.0044 0.004 0.0386
Trichomonas vaginalis PIKK family atypical protein kinase 0.0528 0.0571 0.5606
Trichomonas vaginalis bromodomain-containing protein, putative 0.0049 0.0046 0.0448
Leishmania major ATP-binding cassette protein subfamily B, member 3, putative 0.0044 0.004 0.0107
Echinococcus multilocularis multidrug resistance associated protein 1 0.0044 0.004 0.004
Brugia malayi nuclear receptor NHR-88 0.001 0.0003 0.003
Echinococcus granulosus Phosphatidylinositol 4 kinase type 2 beta 0.018 0.0189 0.0189
Echinococcus multilocularis ATP binding cassette subfamily B (MDR:TAP) 0.014 0.0146 0.0146
Leishmania major hypothetical protein, conserved 0.0015 0.0008 0.002
Entamoeba histolytica phosphatidylinositol 3-kinase 3, putative 0.018 0.0189 0.1861
Schistosoma mansoni jumonji/arid domain-containing protein 0.0035 0.0031 0.03
Onchocerca volvulus 0.0015 0.0008 0.032
Loa Loa (eye worm) hypothetical protein 0.002 0.0014 0.0142
Loa Loa (eye worm) hypothetical protein 0.0139 0.0144 0.1415
Trichomonas vaginalis PIKK family atypical protein kinase 0.0528 0.0571 0.5606
Trypanosoma cruzi phosphatidylinositol 3-kinase vps34-like 0.018 0.0189 0.0546
Plasmodium vivax hexose transporter 0.0104 0.0106 0.2214
Trypanosoma brucei glucose transporter, putative 0.0032 0.0027 0.026
Leishmania major ATP-binding cassette protein subfamily B, member 2, putative 0.014 0.0146 0.0395
Trypanosoma cruzi prolyl-tRNA synthetase, putative 0.0036 0.0032 0.0092
Onchocerca volvulus Rap guanine nucleotide exchange factor 1 homolog 0.0207 0.0219 0.874
Loa Loa (eye worm) hypothetical protein 0.0207 0.0219 0.2153
Echinococcus multilocularis TGF beta signal transducer SmadC 0.0008 0.0001 0.0001
Schistosoma mansoni nuclear transcription factor X-box binding 1 (nfx1) 0.0015 0.0008 0.0079
Trichomonas vaginalis PIKK family atypical protein kinase 0.0937 0.1018 1
Trichomonas vaginalis phosphatidylinositol 3-kinase class, putative 0.018 0.0189 0.1861
Schistosoma mansoni nuclear receptor 2DBD-gamma 0.001 0.0003 0.003
Schistosoma mansoni multidrug resistance protein 0.0044 0.004 0.0394
Brugia malayi Nuclear hormone receptor family member nhr-49 0.001 0.0003 0.003
Mycobacterium ulcerans hypothetical protein 0.0027 0.0022 0.5388
Leishmania major target of rapamycin (TOR) kinase 2, putative 0.0937 0.1018 0.2775
Mycobacterium tuberculosis Probable dicarboxylic acid transport integral membrane protein KgtP (dicarboxylate transporter) 0.0015 0.0008 0.0255
Echinococcus granulosus serine protein kinase ATM 0.0775 0.0841 0.0841
Echinococcus multilocularis multidrug resistance protein 1 0.014 0.0146 0.0146
Schistosoma mansoni coup transcription factor 0.001 0.0003 0.003
Schistosoma mansoni microtubule-associated protein tau 0.0688 0.0746 0.7325
Entamoeba histolytica phosphatidylinositol 3-kinase, putative 0.018 0.0189 0.1861
Plasmodium falciparum protein kinase 7 0.0293 0.0314 0.6595
Giardia lamblia Multidrug resistance-associated protein 1 0.0042 0.0038 0.0301
Schistosoma mansoni bromodomain-containing nuclear protein 1 brd1 0.0029 0.0024 0.0235
Loa Loa (eye worm) hypothetical protein 0.0009 0.0002 0.0023
Echinococcus granulosus lipoxygenase domain containing protein 0.0023 0.0017 0.0017
Schistosoma mansoni histone-lysine n-methyltransferase setb1 0.003 0.0025 0.0242
Mycobacterium tuberculosis Fatty-acid-AMP ligase FadD30 (fatty-acid-AMP synthetase) (fatty-acid-AMP synthase) 0.002 0.0014 0.0482
Schistosoma mansoni ataxia telangiectasia mutated (atm) 0.0775 0.0841 0.8257
Schistosoma mansoni family S12 unassigned peptidase (S12 family) 0.0042 0.0038 0.0369
Brugia malayi jmjC domain containing protein 0.0035 0.0031 0.03
Echinococcus multilocularis ATP binding cassette sub family B 0.0044 0.004 0.004
Schistosoma mansoni lipoxygenase 0.0135 0.014 0.1379
Trichomonas vaginalis sugar transporter, putative 0.0015 0.0008 0.0079
Schistosoma mansoni retinoid-x-receptor (RXR) 0.001 0.0003 0.003
Brugia malayi Phosphatidylinositol 3- and 4-kinase family protein 0.018 0.0189 0.1861
Entamoeba histolytica phosphatidylinositol3-kinaseTor2, putative 0.0937 0.1018 1
Mycobacterium ulcerans acyl-CoA synthetase 0.0027 0.0022 0.5388
Entamoeba histolytica phosphatidylinositol-4,5-bisphosphate 3-kinase, putative 0.018 0.0189 0.1861
Trichomonas vaginalis PIKK family atypical protein kinase 0.0937 0.1018 1
Loa Loa (eye worm) pre-SET domain-containing protein family protein 0.0207 0.0219 0.2155
Trichomonas vaginalis ATP-binding cassette transporter, putative 0.0042 0.0038 0.0378
Leishmania major protein kinase, putative 0.0032 0.0027 0.0071
Echinococcus granulosus inositol monophosphatase 1 0.0037 0.0032 0.0032
Entamoeba histolytica myo-inositol monophosphatase, putative 0.0037 0.0032 0.0318
Brugia malayi Hypothetical 52.5 kDa protein ZK945.1 in chromosome II, putative 0.0042 0.0038 0.0369
Trypanosoma brucei phosphatidylinositol kinase related protein, putative 0.0775 0.0841 0.8256
Plasmodium falciparum LCCL domain-containing protein 0.0023 0.0017 0.0338
Echinococcus multilocularis General substrate transporter 0.0089 0.009 0.009
Echinococcus granulosus jumonji domain containing 1A 0.0009 0.0002 0.0002
Trichomonas vaginalis esterase, putative 0.0042 0.0038 0.0369
Schistosoma mansoni histone-lysine n-methyltransferase setb1 0.003 0.0025 0.0242
Leishmania major ATP-binding cassette protein subfamily C, member 8, putative 0.0044 0.004 0.0107
Plasmodium falciparum phosphatidylinositol 3- and 4-kinase, putative 0.018 0.0189 0.3978
Schistosoma mansoni glucose transporter 0.0015 0.0008 0.0079
Loa Loa (eye worm) hypothetical protein 0.001 0.0003 0.003
Brugia malayi hypothetical protein 0.0044 0.004 0.0394
Entamoeba histolytica P-glyco protein 6, putative 0.014 0.0146 0.1431
Trichomonas vaginalis multidrug resistance protein 1, 2, putative 0.0042 0.0038 0.0378
Echinococcus granulosus calcium:calmodulin dependent protein kinase type 0.0032 0.0027 0.0027
Brugia malayi GTP-binding regulatory protein Gs alpha-S chain, putative 0.0053 0.005 0.049
Trichomonas vaginalis sugar transporter, putative 0.0015 0.0008 0.0079
Loa Loa (eye worm) jmjC domain-containing protein 0.0009 0.0002 0.0023
Trichomonas vaginalis multidrug resistance protein 1, 2, putative 0.014 0.0146 0.1431
Echinococcus granulosus histone lysine methyltransferase setb 0.003 0.0025 0.0025
Onchocerca volvulus 0.0015 0.0008 0.032
Entamoeba histolytica P-glycoprotein-2 0.014 0.0146 0.1431
Echinococcus granulosus solute carrier family 22 0.0015 0.0008 0.0008
Entamoeba histolytica Phosphatidylinositol 3- and 4-kinase family 0.0528 0.0571 0.5606
Brugia malayi Ligand-binding domain of nuclear hormone receptor family protein 0.001 0.0003 0.003
Trichomonas vaginalis taga, putative 0.014 0.0146 0.1431
Trichomonas vaginalis PIKK family atypical protein kinase 0.0937 0.1018 1
Loa Loa (eye worm) hypothetical protein 0.001 0.0003 0.0032
Loa Loa (eye worm) hypothetical protein 0.0594 0.0643 0.6318
Loa Loa (eye worm) nuclear hormone receptor family member nhr-1 0.001 0.0003 0.003
Plasmodium falciparum phosphatidylinositol 4-kinase 0.018 0.0189 0.3978
Plasmodium vivax phosphatidylinositol 3- and 4-kinase, putative 0.018 0.0189 0.3978
Schistosoma mansoni lipoxygenase 0.0095 0.0096 0.0941
Brugia malayi hypothetical protein 0.001 0.0003 0.0032
Mycobacterium leprae Probable prolyl tRNA synthetase ProS 0.0031 0.0026 0.1343
Loa Loa (eye worm) hypothetical protein 0.0015 0.0008 0.0079
Echinococcus multilocularis thyroid hormone receptor alpha 0.001 0.0003 0.0003
Loa Loa (eye worm) nuclear hormone receptor family member nhr-41 0.001 0.0003 0.003
Plasmodium falciparum calcium-dependent protein kinase 3 0.0032 0.0027 0.055
Trichomonas vaginalis lipid A export ATP-binding/permease protein msba, putative 0.014 0.0146 0.1431
Schistosoma mansoni protein phosphatase 2C 0.0009 0.0002 0.0023
Plasmodium vivax multidomain scavenger receptor, putative 0.0023 0.0017 0.0338
Brugia malayi lysyl-tRNA synthetase 0.0023 0.0017 0.0171
Trypanosoma cruzi glucose transporter, putative 0.0015 0.0008 0.0023
Brugia malayi AF-10 protein 0.0009 0.0002 0.0024
Brugia malayi ABC transporter family protein 0.0044 0.004 0.0394
Loa Loa (eye worm) hypothetical protein 0.0044 0.004 0.0394
Trichomonas vaginalis sugar transporter, putative 0.0032 0.0027 0.0268
Schistosoma mansoni smad1 5 8 and 0.0008 0.0001 0.0009
Entamoeba histolytica hypothetical protein 0.0023 0.0017 0.0171
Leishmania major prolyl-tRNA synthetase, putative,bifunctional aminoacyl-tRNA synthetase, putative 0.0036 0.0032 0.0085
Plasmodium vivax sugar transporter, putative 0.0015 0.0008 0.0152
Trichomonas vaginalis multidrug resistance protein 1, 2, putative 0.014 0.0146 0.1431
Trichomonas vaginalis sugar transporter, putative 0.0015 0.0008 0.0079
Schistosoma mansoni phosphatidylinositol-45-bisphosphate 3-kinase catalytic subunit alpha PI3K 0.018 0.0189 0.1861
Trichomonas vaginalis ATP-binding cassette transporter, putative 0.014 0.0146 0.1431
Schistosoma mansoni multidrug resistance protein 0.0042 0.0038 0.0378
Entamoeba histolytica long-chain-fatty-acid--CoA ligase, putative 0.0008 0.0001 0.0008
Echinococcus multilocularis phosphatidylinositol 3 and 4 kinase 0.0937 0.1018 0.1018
Toxoplasma gondii WD domain, G-beta repeat-containing protein 0.0009 0.0002 0.0016
Brugia malayi Major Facilitator Superfamily protein 0.0015 0.0008 0.0079
Loa Loa (eye worm) hypothetical protein 0.0023 0.0017 0.0171
Schistosoma mansoni ATP-binding cassette sub-family B member 6 mitochondrial precursor (abc6) 0.0042 0.0038 0.0378
Echinococcus granulosus solute carrier family 2 facilitated glucose 0.0104 0.0106 0.0106
Brugia malayi PHD-finger family protein 0.0029 0.0024 0.0235
Brugia malayi ABC transporter family protein 0.0044 0.004 0.0394
Mycobacterium tuberculosis Probable lipase LipE 0.0042 0.0038 0.1302
Mycobacterium ulcerans integral membrane transport protein 0.0015 0.0008 0.1832
Trichomonas vaginalis sugar transporter, putative 0.0015 0.0008 0.0079
Trypanosoma cruzi phosphatidylinositol kinase related protein, putative 0.0775 0.0841 0.2423
Echinococcus granulosus glutamyl tRNA synthetase cytoplasmic 0.0031 0.0026 0.0026
Trichomonas vaginalis PIKK family atypical protein kinase 0.0937 0.1018 1
Echinococcus granulosus multidrug resistance protein 1 0.014 0.0146 0.0146
Echinococcus multilocularis segment polarity protein dishevelled 0.001 0.0003 0.0003
Schistosoma mansoni hypothetical protein 0.018 0.0189 0.1861
Giardia lamblia ABC transporter, putative 0.0044 0.004 0.0318
Loa Loa (eye worm) AMP-binding enzyme family protein 0.0008 0.0001 0.0008
Mycobacterium tuberculosis Probable hydrolase 0.0042 0.0038 0.1302
Echinococcus multilocularis ATP binding cassette subfamily B (MDR:TAP) 0.014 0.0146 0.0146
Leishmania major p-glycoprotein e 0.0044 0.004 0.0107
Mycobacterium tuberculosis Conserved protein 0.0042 0.0038 0.1302
Plasmodium vivax calcium-dependent protein kinase, putative 0.0032 0.0027 0.055
Plasmodium falciparum hexose transporter 0.0104 0.0106 0.2214
Loa Loa (eye worm) phosphatidylinositol 3 0.018 0.0189 0.1861
Brugia malayi hypothetical protein 0.001 0.0003 0.0032
Loa Loa (eye worm) hypothetical protein 0.0008 0.0001 0.0008
Schistosoma mansoni ATP-binding cassette sub-family B member 7 mitochondrial precursor (abc7) 0.0044 0.004 0.0394
Chlamydia trachomatis lysine--tRNA ligase 0.0023 0.0017 0.0942
Trichomonas vaginalis multidrug resistance protein 1, 2, putative 0.014 0.0146 0.1431
Leishmania major ATP-binding cassette protein subfamily C, member 2, putative 0.0044 0.004 0.0107
Brugia malayi jmjC domain containing protein 0.0009 0.0002 0.0023
Loa Loa (eye worm) phosphatidylinositol kinase 0.018 0.0189 0.1861
Echinococcus multilocularis lipoxygenase domain containing protein 0.0023 0.0017 0.0017
Echinococcus multilocularis histone lysine methyltransferase setb histone lysine methyltransferase eggless 0.003 0.0025 0.0025
Trypanosoma cruzi myo-inositol-1(or 4)-monophosphatase 1, putative 0.0037 0.0032 0.0093
Brugia malayi Nuclear hormone receptor family member nhr-25 0.001 0.0003 0.003
Mycobacterium ulcerans sugar transporter 0.0015 0.0008 0.1832
Schistosoma mansoni protein kinase 0.0032 0.0027 0.0264
Loa Loa (eye worm) jmjC domain-containing protein 0.0009 0.0002 0.0023
Entamoeba histolytica ATP-binding cassette protein, putative 0.0044 0.004 0.0394
Echinococcus granulosus multidrug resistance protein 1 0.014 0.0146 0.0146
Brugia malayi beta-lactamase family protein 0.0042 0.0038 0.0369
Leishmania major target of rapamycin kinase (TOR) kinase 3 0.0937 0.1018 0.2775
Trichomonas vaginalis sugar transporter, putative 0.0015 0.0008 0.0079
Loa Loa (eye worm) hypothetical protein 0.002 0.0014 0.0142
Mycobacterium leprae PROBABLE FATTY-ACID-CoA LIGASE FADD7 (FATTY-ACID-CoA SYNTHETASE) (FATTY-ACID-CoA SYNTHASE) 0.0027 0.0022 0.1122
Toxoplasma gondii histone lysine acetyltransferase GCN5-A 0.0049 0.0046 0.0441
Loa Loa (eye worm) phosphatidylinositol 3 0.018 0.0189 0.1861
Echinococcus multilocularis Transcription factor, JmjC domain containing protein 0.0095 0.0096 0.0096
Plasmodium falciparum ABC transporter B family member 7, putative 0.0044 0.004 0.0829
Entamoeba histolytica P-glycoprotein-2, putative 0.0042 0.0038 0.0378
Onchocerca volvulus Putative transporter 0.0015 0.0008 0.032
Onchocerca volvulus 0.014 0.0146 0.5811
Loa Loa (eye worm) bifunctional aminoacyl-tRNA synthetase 0.0013 0.0006 0.0059
Echinococcus granulosus arachidonate 5 lipoxygenase 0.0135 0.014 0.014
Brugia malayi Nuclear hormone receptor family member nhr-19 0.001 0.0003 0.003
Mycobacterium tuberculosis Conserved protein 0.0042 0.0038 0.1302
Trypanosoma cruzi ABC transporter of the mitochondrion, putative 0.0044 0.004 0.0116
Loa Loa (eye worm) hypothetical protein 0.0044 0.004 0.0394
Echinococcus multilocularis Pleckstrin G protein, interacting region 0.001 0.0003 0.0003
Trichomonas vaginalis D-aminoacylase, putative 0.0042 0.0038 0.0369
Schistosoma mansoni serine/threonine protein kinase 0.0032 0.0027 0.0264
Plasmodium vivax CDK-related protein kinase 6, putative 0.0441 0.0475 1
Brugia malayi jmjC domain containing protein 0.0095 0.0096 0.0946
Loa Loa (eye worm) hypothetical protein 0.001 0.0003 0.003
Schistosoma mansoni dishevelled 0.001 0.0003 0.0032
Onchocerca volvulus 0.001 0.0003 0.0128
Trichomonas vaginalis sugar transporter, putative 0.0015 0.0008 0.0079
Brugia malayi AMP-binding enzyme family protein 0.0008 0.0001 0.0008
Loa Loa (eye worm) hypothetical protein 0.003 0.0025 0.0242
Trichomonas vaginalis PIKK family atypical protein kinase 0.0937 0.1018 1
Schistosoma mansoni photoreceptor-specific nuclear receptor related 0.001 0.0003 0.003
Leishmania major phosphatidylinositol 4-kinase, putative 0.018 0.0189 0.0515
Trichomonas vaginalis PIKK family atypical protein kinase 0.0937 0.1018 1
Brugia malayi Nuclear hormone receptor-like 1 0.001 0.0003 0.003
Echinococcus multilocularis jumonji domain containing protein 0.004 0.0036 0.0036
Schistosoma mansoni glucose transport protein 0.0104 0.0106 0.1039
Brugia malayi hypothetical protein 0.0015 0.0008 0.0079
Trichomonas vaginalis ABC transporter, putative 0.014 0.0146 0.1431
Trichomonas vaginalis sugar transporter, putative 0.0015 0.0008 0.0079
Loa Loa (eye worm) hypothetical protein 0.002 0.0014 0.0142
Plasmodium falciparum ABC transporter B family member 4, putative 0.0044 0.004 0.0829
Brugia malayi major facilitator superfamily protein 0.0015 0.0008 0.0079
Trichomonas vaginalis conserved hypothetical protein 0.0015 0.0008 0.0079
Giardia lamblia Lysyl-tRNA synthetase 0.0023 0.0017 0.0093
Onchocerca volvulus 0.018 0.0189 0.7554
Loa Loa (eye worm) hypothetical protein 0.001 0.0003 0.003
Onchocerca volvulus 0.0015 0.0008 0.032
Loa Loa (eye worm) hypothetical protein 0.0015 0.0008 0.0079
Trichomonas vaginalis sugar transporter, putative 0.0015 0.0008 0.0079
Plasmodium vivax phosphatidylinositol 4-kinase, putative 0.018 0.0189 0.3978
Brugia malayi photoreceptor-specific nuclear receptor 0.001 0.0003 0.003
Mycobacterium ulcerans drugs-transport transmembrane ATP-binding protein ABC transporter 0.0044 0.004 1
Toxoplasma gondii ABC transporter transmembrane region domain-containing protein 0.014 0.0146 0.1424
Leishmania major hypothetical protein, conserved 0.0042 0.0038 0.01
Entamoeba histolytica hypothetical protein 0.0775 0.0841 0.8257
Trichomonas vaginalis glucose transporter, putative 0.0032 0.0027 0.0268
Echinococcus multilocularis serine:threonine protein kinase SMG1 0.0528 0.0571 0.0571
Plasmodium falciparum ABC transporter B family member 6, putative 0.0044 0.004 0.0829
Trichomonas vaginalis PIKK family atypical protein kinase 0.0937 0.1018 1
Echinococcus multilocularis RUN 0.0023 0.0017 0.0017
Echinococcus multilocularis phosphatidylinositol 4 kinase alpha 0.018 0.0189 0.0189
Schistosoma mansoni transcription factor LCR-F1 0.0041 0.0037 0.0366
Trypanosoma cruzi long-chain-fatty-acid-CoA ligase, putative 0.0008 0.0001 0.0002
Trypanosoma brucei phosphatidylinositol 4-kinase alpha, putative 0.018 0.0189 0.1854
Mycobacterium tuberculosis Conserved hypothetical protein 0.018 0.0189 0.6689
Loa Loa (eye worm) hypothetical protein 0.0015 0.0008 0.0079
Echinococcus multilocularis calcium dependent protein kinase 0.003 0.0025 0.0025
Loa Loa (eye worm) hypothetical protein 0.0015 0.0008 0.0079
Trypanosoma cruzi target of rapamycin kinase 3 0.0937 0.1018 0.2935
Echinococcus granulosus histone acetyltransferase KAT2B 0.0162 0.0169 0.0169
Onchocerca volvulus 0.0015 0.0008 0.032
Entamoeba histolytica ABC transporter, putative 0.0044 0.004 0.0394
Echinococcus granulosus phosphatidylinositol 4 kinase beta 0.018 0.0189 0.0189
Schistosoma mansoni phd/f-box containing protein 0.0009 0.0002 0.0023
Schistosoma mansoni z-protein (S1r protein) 0.001 0.0003 0.0032
Trichomonas vaginalis phopsphatidylinositol 3-kinase, drosophila, putative 0.018 0.0189 0.1861
Toxoplasma gondii target of rapamycin (TOR), putative 0.0937 0.1018 1
Loa Loa (eye worm) major facilitator superfamily transporter 0.0015 0.0008 0.0079
Echinococcus granulosus microtubule associated protein 2 0.0688 0.0746 0.0746
Trichomonas vaginalis PIKK family atypical protein kinase 0.0937 0.1018 1
Schistosoma mansoni lysyl-tRNA synthetase 0.0023 0.0017 0.0171
Echinococcus granulosus FTZ F1 alpha 0.001 0.0003 0.0003
Echinococcus granulosus beta LACTamase domain containing family member 0.0042 0.0038 0.0038
Loa Loa (eye worm) transcription factor SMAD2 0.0119 0.0122 0.1203
Echinococcus multilocularis calcium:calmodulin dependent protein kinase type 0.0032 0.0027 0.0027
Brugia malayi acetyl-Coenzyme A synthetase 2 0.0008 0.0001 0.0008
Brugia malayi hypothetical protein 0.0236 0.025 0.2459
Wolbachia endosymbiont of Brugia malayi ABC-type multidrug transport system, ATPase and permease component 0.0044 0.004 1
Leishmania major phosphatidylinositol 3-kinase, putative 0.018 0.0189 0.0515
Echinococcus multilocularis ATP binding cassette sub family B 0.0044 0.004 0.004
Trypanosoma cruzi phosphatidylinositol 4-kinase alpha, putative 0.018 0.0189 0.0546
Trypanosoma cruzi phosphatidylinositol 3-related kinase, putative 0.0937 0.1018 0.2935
Trichomonas vaginalis multidrug resistance protein 1, 2, putative 0.014 0.0146 0.1431
Trichomonas vaginalis ABC transporter, half transporter, putative 0.014 0.0146 0.1431
Mycobacterium tuberculosis Inositol-1-monophosphatase SuhB 0.0033 0.0028 0.0969
Trichomonas vaginalis PIKK family atypical protein kinase 0.0775 0.0841 0.8257
Echinococcus granulosus PIK kinase FAT and Armadillo domain containing protein 0.0408 0.044 0.044
Toxoplasma gondii ABC1 family protein 0.0042 0.0038 0.0361
Loa Loa (eye worm) hypothetical protein 0.0236 0.025 0.2459
Mycobacterium tuberculosis Lysyl-tRNA synthetase 2 LysX 0.002 0.0014 0.0453
Trichomonas vaginalis multidrug resistance protein 1, 2, putative 0.014 0.0146 0.1431
Echinococcus granulosus acetyl coenzyme A synthetase cytoplasmic 0.0008 0.0001 0.0001
Loa Loa (eye worm) hypothetical protein 0.0044 0.004 0.0394
Mycobacterium leprae possible inositol monophosphatase SubH (IMPase) (inositol-1-phosphatase) (I-1-Pase ). 0.0033 0.0028 0.1448
Mycobacterium ulcerans transmembrane ABC transporter ATP-binding protein 0.0044 0.004 1
Onchocerca volvulus 0.0015 0.0008 0.032
Trichomonas vaginalis sugar transporter, putative 0.0015 0.0008 0.0079
Echinococcus multilocularis peregrin 0.0033 0.0028 0.0028
Echinococcus multilocularis ATP binding cassette sub family B 0.0044 0.004 0.004
Trypanosoma brucei THT1 - hexose transporter, putative 0.0032 0.0027 0.026
Mycobacterium tuberculosis Probable fatty-acid-CoA ligase FadD35 (fatty-acid-CoA synthetase) (fatty-acid-CoA synthase) 0.0019 0.0013 0.0439
Plasmodium vivax hypothetical protein, conserved 0.018 0.0189 0.3978
Brugia malayi Inositol-1 0.0037 0.0032 0.0318
Onchocerca volvulus 0.0023 0.0017 0.0671
Schistosoma mansoni phosphatidylserine receptor 0.0009 0.0002 0.0023
Onchocerca volvulus 0.0015 0.0008 0.032
Trichomonas vaginalis sugar transporter, putative 0.0015 0.0008 0.0079
Schistosoma mansoni TGF-beta signal transducer Smad2 0.0008 0.0001 0.0009
Echinococcus granulosus calcium:calmodulin dependent protein kinase type 1 0.0032 0.0027 0.0027
Brugia malayi hypothetical protein 0.0015 0.0008 0.0079
Trypanosoma brucei THT1 - hexose transporter, putative 0.0032 0.0027 0.026
Trichomonas vaginalis lysyl-tRNA synthetase, putative 0.002 0.0014 0.014
Trichomonas vaginalis PIKK family atypical protein kinase 0.0937 0.1018 1
Echinococcus multilocularis ATP binding cassette subfamily B (MDR:TAP) 0.014 0.0146 0.0146
Trichomonas vaginalis PIKK family atypical protein kinase 0.0937 0.1018 1
Brugia malayi AMP-binding enzyme family protein 0.0027 0.0022 0.0216
Trichomonas vaginalis inositol monophosphatase, putative 0.0037 0.0032 0.0318
Loa Loa (eye worm) phosphatidylinositol 3 0.0937 0.1018 1
Schistosoma mansoni hypothetical protein 0.0009 0.0002 0.0024
Loa Loa (eye worm) nuclear Hormone Receptor family member 0.001 0.0003 0.003
Schistosoma mansoni fkbp-rapamycin associated protein 0.0528 0.0571 0.5606
Trichomonas vaginalis PIKK family atypical protein kinase 0.0937 0.1018 1
Plasmodium vivax lysine--tRNA ligase, putative 0.0023 0.0017 0.035
Trichomonas vaginalis conserved hypothetical protein 0.0408 0.044 0.4316
Toxoplasma gondii ABC transporter transmembrane region domain-containing protein 0.0044 0.004 0.0386
Plasmodium falciparum multidrug resistance-associated protein 2 0.0044 0.004 0.0829
Echinococcus granulosus ATP binding cassette sub family B 0.0044 0.004 0.004
Trypanosoma brucei multidrug resistance-associated protein, putative 0.0044 0.004 0.0386
Trichomonas vaginalis PIKK family atypical protein kinase 0.0528 0.0571 0.5606
Brugia malayi bifunctional aminoacyl-tRNA synthetase 0.0031 0.0026 0.0257
Brugia malayi Major Facilitator Superfamily protein 0.0015 0.0008 0.0079
Mycobacterium tuberculosis Probable conserved lipoprotein 0.0042 0.0038 0.1302
Trichomonas vaginalis sugar transporter, putative 0.0015 0.0008 0.0079
Entamoeba histolytica ATP-binding cassette protein, putative 0.0044 0.004 0.0394
Giardia lamblia Hypothetical protein 0.018 0.0189 0.1796
Onchocerca volvulus 0.0015 0.0008 0.032
Echinococcus multilocularis Zinc finger, PHD finger 0.018 0.0189 0.0189
Leishmania major lysyl-tRNA synthetase, putative 0.0023 0.0017 0.0045
Brugia malayi jmjC domain containing protein 0.0009 0.0002 0.0023
Trichomonas vaginalis ATP-binding cassette transporter, putative 0.0098 0.0099 0.0976
Loa Loa (eye worm) hypothetical protein 0.0015 0.0008 0.0079
Trichomonas vaginalis conserved hypothetical protein 0.0015 0.0008 0.0079
Trichomonas vaginalis glucose transporter, putative 0.0032 0.0027 0.0268
Echinococcus granulosus mothers against decapentaplegic 5 0.0008 0.0001 0.0001
Schistosoma mansoni rab6-interacting 0.0023 0.0017 0.0165
Brugia malayi Iron-sulfur cluster assembly accessory protein 0.0048 0.0045 0.0439
Entamoeba histolytica prolyl-tRNA synthetase, putative 0.0031 0.0026 0.0257
Leishmania major phosphatidylinositol 3-kinase, putative 0.0937 0.1018 0.2775
Schistosoma mansoni smdr1 0.0044 0.004 0.0394
Trichomonas vaginalis PIKK family atypical protein kinase 0.0348 0.0373 0.3667
Brugia malayi acetyltransferase, GNAT family protein 0.0166 0.0174 0.1713
Plasmodium falciparum calcium-dependent protein kinase 2 0.0032 0.0027 0.055
Mycobacterium tuberculosis Possible penicillin-binding protein 0.0265 0.0283 1
Trichomonas vaginalis penicillin-binding protein, putative 0.0042 0.0038 0.0369
Echinococcus granulosus multidrug resistance protein 1 0.0098 0.0099 0.0099
Trichomonas vaginalis PIKK family atypical protein kinase 0.0937 0.1018 1
Onchocerca volvulus 0.0008 0.0001 0.0033
Trichomonas vaginalis conserved hypothetical protein 0.0042 0.0038 0.0378
Trichomonas vaginalis sugar transporter, putative 0.0015 0.0008 0.0079
Echinococcus granulosus multidrug resistance protein 1 0.014 0.0146 0.0146
Echinococcus multilocularis COUP TF:Svp nuclear hormone receptor 0.001 0.0003 0.0003
Loa Loa (eye worm) jmjC domain-containing protein 0.0035 0.0031 0.03
Loa Loa (eye worm) hypothetical protein 0.0042 0.0038 0.0369
Trichomonas vaginalis sugar transporter, putative 0.0015 0.0008 0.0079
Brugia malayi Nuclear hormone receptor family member nhr-3 0.001 0.0003 0.003
Toxoplasma gondii phosphatidylinositol 3- and 4-kinase 0.018 0.0189 0.1854
Mycobacterium ulcerans lysyl-tRNA synthetase 0.0023 0.0017 0.4225
Plasmodium vivax SET domain protein, putative 0.003 0.0025 0.0502
Trichomonas vaginalis PIKK family atypical protein kinase 0.0937 0.1018 1
Echinococcus granulosus COUP TF:Svp nuclear hormone receptor 0.001 0.0003 0.0003
Loa Loa (eye worm) hypothetical protein 0.0042 0.0038 0.0378
Toxoplasma gondii ABC transporter transmembrane region domain-containing protein 0.0044 0.004 0.0386
Echinococcus multilocularis guanine nucleotide binding protein G(s) subunit 0.0053 0.005 0.005
Echinococcus granulosus Sugar transporter ERD6 protein 0.0015 0.0008 0.0008
Echinococcus granulosus peregrin 0.0033 0.0028 0.0028
Schistosoma mansoni survival motor neuron protein 0.0048 0.0045 0.0439
Echinococcus multilocularis calcium:calmodulin dependent protein kinase type 0.0032 0.0027 0.0027
Onchocerca volvulus 0.0236 0.0251 1
Trypanosoma brucei glucose transporter, putative 0.0032 0.0027 0.026
Loa Loa (eye worm) acetyltransferase 0.0166 0.0174 0.1713
Trichomonas vaginalis conserved hypothetical protein 0.0104 0.0106 0.1039
Echinococcus granulosus FTZ F1 nuclear receptor protein 0.001 0.0003 0.0003
Loa Loa (eye worm) hypothetical protein 0.018 0.0189 0.1861
Trichomonas vaginalis conserved hypothetical protein 0.0015 0.0008 0.0079
Brugia malayi hypothetical protein 0.0041 0.0037 0.0366
Loa Loa (eye worm) hypothetical protein 0.001 0.0003 0.003
Echinococcus granulosus phosphatidylinositol 45 bisphosphate 3 kinase 0.018 0.0189 0.0189
Loa Loa (eye worm) jmjC domain-containing protein 0.0009 0.0002 0.0023
Echinococcus multilocularis regulator of G protein signaling 7 0.001 0.0003 0.0003
Plasmodium vivax hypothetical protein, conserved 0.0009 0.0002 0.0034
Onchocerca volvulus 0.0008 0.0001 0.0033
Loa Loa (eye worm) hypothetical protein 0.0042 0.0038 0.0369
Echinococcus granulosus nuclear receptor 2DBD gamma 0.001 0.0003 0.0003
Echinococcus granulosus Pleckstrin G protein interacting region 0.001 0.0003 0.0003
Toxoplasma gondii phosphatidylinositol 3- and 4-kinase 0.018 0.0189 0.1854
Toxoplasma gondii ABC transporter, putative 0.0044 0.004 0.0386
Echinococcus granulosus ATP binding cassette sub family B 0.0042 0.0038 0.0038
Trypanosoma cruzi phosphatidylinositol 4-kinase, putative 0.018 0.0189 0.0546
Trypanosoma cruzi hexose transporter, putative 0.0015 0.0008 0.0023
Echinococcus granulosus ATP binding cassette subfamily B MDR:TAP 0.014 0.0146 0.0146
Onchocerca volvulus 0.0015 0.0008 0.032
Toxoplasma gondii histone lysine acetyltransferase GCN5-B 0.0049 0.0046 0.0441
Loa Loa (eye worm) hypothetical protein 0.0023 0.0017 0.0165
Brugia malayi MH1 domain containing protein 0.0008 0.0001 0.0009
Echinococcus granulosus calcium:calmodulin dependent protein kinase type 0.0032 0.0027 0.0027
Echinococcus granulosus solute carrier family 22 0.0015 0.0008 0.0008
Schistosoma mansoni glutamyl-tRNA synthetase cytoplasmic (glutamate--tRNA ligase) (glurs) 0.0031 0.0026 0.0257
Treponema pallidum prolyl-tRNA synthetase 0.0011 0.0004 0.5
Trypanosoma cruzi hexose transporter, putative 0.0032 0.0027 0.0079
Brugia malayi ABC transporter transmembrane region family protein 0.0044 0.004 0.0394
Echinococcus granulosus hepatocyte nuclear factor 4 alpha 0.001 0.0003 0.0003
Trypanosoma brucei glucose transporter, putative 0.0032 0.0027 0.026
Trypanosoma cruzi multidrug resistance-associated protein, putative 0.0044 0.004 0.0116
Echinococcus granulosus ATP binding cassette sub family B 0.0044 0.004 0.004
Echinococcus granulosus geminin 0.0186 0.0195 0.0195
Loa Loa (eye worm) hypothetical protein 0.0015 0.0008 0.0079
Toxoplasma gondii PHD-finger domain-containing protein 0.0029 0.0024 0.0227
Schistosoma mansoni Smad4 0.0008 0.0001 0.0009
Trypanosoma brucei phosphatidylinositol 3-kinase, putative 0.0937 0.1018 1
Leishmania major glucose transporter, lmgt2 0.0032 0.0027 0.0072
Echinococcus granulosus multidrug resistance associated protein 7 0.0044 0.004 0.004
Chlamydia trachomatis ABC transporter ATP binding protein/permease 0.014 0.0146 1
Trypanosoma brucei calcium/calmodulin-dependent protein kinase, putative 0.0032 0.0027 0.0256
Onchocerca volvulus 0.0042 0.0038 0.1497
Trichomonas vaginalis PIKK family atypical protein kinase 0.018 0.0189 0.1861
Echinococcus granulosus solute carrier family 2 facilitated glucose 0.0104 0.0106 0.0106
Echinococcus multilocularis ATP binding cassette sub family B 0.0044 0.004 0.004
Mycobacterium leprae Possible lysyl-tRNA synthetase 2 LysX 0.0023 0.0017 0.088
Echinococcus granulosus calcium:calmodulin dependent protein kinase type 0.0032 0.0027 0.0027
Onchocerca volvulus 0.0015 0.0008 0.032
Echinococcus multilocularis hepatocyte nuclear factor 4 alpha 0.001 0.0003 0.0003
Trypanosoma brucei multidrug resistance-associated protein, putative 0.0044 0.004 0.0386
Loa Loa (eye worm) hypothetical protein 0.0009 0.0002 0.0023
Toxoplasma gondii facilitative glucose transporter GT1 0.0104 0.0106 0.1032
Schistosoma mansoni phosphatidylinositol 4-kinase 0.018 0.0189 0.1861
Echinococcus multilocularis Jumonji, AT rich interactive domain 1B 0.0009 0.0002 0.0002
Echinococcus granulosus solute carrier family 2 facilitated glucose 0.0104 0.0106 0.0106
Brugia malayi P-glycoprotein-like protein 0.0044 0.004 0.0394
Giardia lamblia PHD finger protein 15 0.0029 0.0024 0.0157
Leishmania major ABC-thiol transporter 0.0044 0.004 0.0107
Toxoplasma gondii calcium-dependent protein kinase CDPK2A 0.0032 0.0027 0.0256
Trichomonas vaginalis lipid A export ATP-binding/permease protein msba, putative 0.014 0.0146 0.1431
Brugia malayi Phosphatidylinositol 3- and 4-kinase family protein 0.018 0.0189 0.1861
Trichomonas vaginalis ABC transporter, putative 0.014 0.0146 0.1431
Onchocerca volvulus Bile acid receptor homolog 0.001 0.0003 0.0122
Echinococcus multilocularis atpase aaa+ type core atpase aaa type core 0.0931 0.1013 0.1013
Brugia malayi major facilitator superfamily protein 0.0015 0.0008 0.0079
Trichomonas vaginalis sugar transporter, putative 0.0015 0.0008 0.0079
Brugia malayi Smad1 0.0008 0.0001 0.0009
Trichomonas vaginalis sugar transporter, putative 0.0015 0.0008 0.0079
Trichomonas vaginalis lipid A export ATP-binding/permease protein msba, putative 0.014 0.0146 0.1431
Trypanosoma cruzi phosphatidylinositol kinase related protein, putative 0.0427 0.046 0.1324
Schistosoma mansoni multidrug resistance protein 0.0044 0.004 0.0394
Brugia malayi Phosphatidylinositol 3- and 4-kinase family protein 0.0775 0.0841 0.8257
Trypanosoma cruzi JmjC domain, hydroxylase, putative 0.0009 0.0002 0.0007
Onchocerca volvulus 0.0015 0.0008 0.032
Mycobacterium ulcerans long-chain fatty-acid CoA ligase 0.0027 0.0022 0.5388
Trypanosoma brucei FAT domain/Rapamycin binding domain/Phosphatidylinositol 3- and 4-kinase, putative 0.0589 0.0637 0.6252
Trichomonas vaginalis lipid A export ATP-binding/permease protein msba, putative 0.014 0.0146 0.1431
Trichomonas vaginalis sugar transporter, putative 0.0015 0.0008 0.0079
Mycobacterium tuberculosis Probable esterase LipL 0.0042 0.0038 0.1302
Plasmodium falciparum calcium-dependent protein kinase 1 0.0032 0.0027 0.055
Loa Loa (eye worm) DIX domain-containing protein 0.001 0.0003 0.0032
Mycobacterium tuberculosis Probable fatty-acid-CoA ligase FadD3 (fatty-acid-CoA synthetase) (fatty-acid-CoA synthase) 0.0019 0.0013 0.0439
Brugia malayi Sugar transporter family protein 0.0015 0.0008 0.0079
Trypanosoma brucei p-glycoprotein 0.0044 0.004 0.0386
Plasmodium vivax ABC transporter B family member 7, putative 0.0044 0.004 0.0829
Echinococcus multilocularis PIK kinase, FAT and Armadillo domain containing protein 0.0408 0.044 0.044
Trichomonas vaginalis phosphatidylinositol 4-kinase, putative 0.018 0.0189 0.1861
Toxoplasma gondii ABC transporter transmembrane region domain-containing protein 0.0044 0.004 0.0386
Loa Loa (eye worm) nuclear hormone receptor family member nhr-31 0.001 0.0003 0.003
Trypanosoma brucei glucose transporter, putative 0.0032 0.0027 0.026
Trypanosoma cruzi Phosphatidylinositol 3-kinase tor1 0.0937 0.1018 0.2935
Plasmodium vivax ABC transporter B family member 4, putative 0.0044 0.004 0.0829
Echinococcus granulosus solute carrier family 22 0.0015 0.0008 0.0008
Toxoplasma gondii inositol(myo)-1(or 4)-monophosphatase 2, putative 0.0037 0.0032 0.031
Leishmania major ATP-binding cassette protein subfamily C, member 5, putative 0.0044 0.004 0.0107
Schistosoma mansoni Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) 0.0053 0.005 0.049
Echinococcus granulosus Transcription factor JmjC domain containing protein 0.0095 0.0096 0.0096
Schistosoma mansoni hypothetical protein 0.0186 0.0195 0.1918
Trichomonas vaginalis sugar transporter, putative 0.0015 0.0008 0.0079
Echinococcus granulosus phosphatidylinositol 3 kinase catalytic subunit 0.018 0.0189 0.0189
Trichomonas vaginalis ATP-binding cassette transporter, putative 0.014 0.0146 0.1431
Brugia malayi MH2 domain containing protein 0.0119 0.0122 0.1203
Leishmania major target of rapamycin (TOR) kinase 1, putative 0.0937 0.1018 0.2775
Loa Loa (eye worm) Smad1 0.0008 0.0001 0.0009
Trichomonas vaginalis sugar transporter, putative 0.0015 0.0008 0.0079
Trichomonas vaginalis antibiotic synthetase, putative 0.0008 0.0001 0.0008
Onchocerca volvulus 0.0015 0.0008 0.032
Loa Loa (eye worm) jmjC domain-containing protein 0.006 0.0058 0.0568
Echinococcus granulosus phosphatidylinositol 4 phosphate 3 kinase C2 0.018 0.0189 0.0189
Loa Loa (eye worm) hypothetical protein 0.001 0.0003 0.0032
Loa Loa (eye worm) ABC transporter 0.0044 0.004 0.0394
Loa Loa (eye worm) hypothetical protein 0.0031 0.0026 0.0257
Echinococcus multilocularis FTZ F1 alpha 0.001 0.0003 0.0003
Toxoplasma gondii ABC transporter family protein 0.0044 0.004 0.0386
Echinococcus multilocularis ATP binding cassette sub family B 0.0139 0.0144 0.0144
Entamoeba histolytica acyl-coA synthetase, putative 0.0027 0.0022 0.0216
Brugia malayi Domain found in Dishevelled, Egl-10, and Pleckstrin family protein 0.001 0.0003 0.0032
Echinococcus granulosus 5'partial|ATP binding cassette sub family B 0.0139 0.0144 0.0144
Giardia lamblia Hypothetical protein 0.0042 0.0038 0.0301
Trypanosoma cruzi Phosphatidylinositol 3-kinase tor2 0.0937 0.1018 0.2935
Schistosoma mansoni phosphatidylinositol 3-kinase class 0.018 0.0189 0.1861
Toxoplasma gondii histone lysine demethylase JMJC1/KDM5D/JARID1D 0.0009 0.0002 0.0015
Plasmodium vivax hypothetical protein 0.018 0.0189 0.3978
Trypanosoma cruzi hypothetical protein, conserved 0.0042 0.0038 0.0108
Loa Loa (eye worm) MH2 domain-containing protein 0.0008 0.0001 0.0009
Echinococcus multilocularis glutamyl tRNA synthetase cytoplasmic 0.0031 0.0026 0.0026
Trypanosoma brucei ABC transporter, mitochondrial, putative 0.0044 0.004 0.0386
Brugia malayi Major Facilitator Superfamily protein 0.0015 0.0008 0.0079
Loa Loa (eye worm) hypothetical protein 0.0528 0.0571 0.5606
Loa Loa (eye worm) hypothetical protein 0.002 0.0014 0.0142
Trichomonas vaginalis CAMK family protein kinase 0.0032 0.0027 0.0264
Leishmania major hypothetical protein, conserved 0.0009 0.0002 0.0004
Toxoplasma gondii cell-cycle-associated protein kinase MAPK, putative 0.0168 0.0176 0.1721
Brugia malayi F/Y-rich N-terminus family protein 0.0011 0.0004 0.0036
Mycobacterium ulcerans component linked with the assembly of cytochrome transport transmembrane ATP-binding protein ABC transporter CydD 0.0044 0.004 1
Schistosoma mansoni glutamyl-tRNA synthetase cytoplasmic (glutamate--tRNA ligase) (glurs) 0.0031 0.0026 0.0257
Echinococcus multilocularis regulator of G protein signaling 7 0.001 0.0003 0.0003
Trichomonas vaginalis antibiotic synthetase, putative 0.0008 0.0001 0.0008
Mycobacterium tuberculosis Probable chain -fatty-acid-CoA ligase FadD13 (fatty-acyl-CoA synthetase) 0.0027 0.0022 0.0751
Trypanosoma brucei sugar transporter, putative 0.0015 0.0008 0.0071
Trichomonas vaginalis PIKK family atypical protein kinase 0.0589 0.0637 0.6255
Schistosoma mansoni multidrug resistance protein 0.014 0.0146 0.1431
Onchocerca volvulus Segment polarity protein dishevelled homolog 0.001 0.0003 0.0128
Onchocerca volvulus 0.0023 0.0017 0.0671
Entamoeba histolytica P-glycoprotein-1 0.014 0.0146 0.1431
Mycobacterium ulcerans long-chain-fatty-acid--CoA ligase 0.0027 0.0022 0.5388
Trypanosoma brucei multidrug resistance protein E 0.0044 0.004 0.0386
Trichomonas vaginalis sugar transporter, putative 0.0015 0.0008 0.0079
Loa Loa (eye worm) hypothetical protein 0.0032 0.0027 0.0264
Toxoplasma gondii protein kinase, putative 0.0293 0.0314 0.3074
Brugia malayi Nuclear hormone receptor family member nhr-41 0.001 0.0003 0.003
Trichomonas vaginalis multidrug resistance protein 1, 2, putative 0.014 0.0146 0.1431
Onchocerca volvulus 0.0015 0.0008 0.032
Schistosoma mansoni hypothetical protein 0.0408 0.044 0.4316
Trichomonas vaginalis sugar transport protein, putative 0.0015 0.0008 0.0079
Trichomonas vaginalis phopsphatidylinositol 3-kinase, drosophila, putative 0.018 0.0189 0.1861
Trichomonas vaginalis PIKK family atypical protein kinase 0.0937 0.1018 1
Brugia malayi steroid hormone receptor 0.001 0.0003 0.003
Brugia malayi Bifunctional aminoacyl-tRNA synthetase 0.0031 0.0026 0.0257
Mycobacterium tuberculosis Possible conserved lipoprotein LpqK 0.0042 0.0038 0.1302
Trichomonas vaginalis phosphatidylinositol kinase, putative 0.018 0.0189 0.1861
Echinococcus multilocularis geminin 0.0186 0.0195 0.0195
Toxoplasma gondii PHD-finger domain-containing protein 0.0029 0.0024 0.0227
Echinococcus multilocularis multidrug resistance protein 1 0.0098 0.0099 0.0099
Onchocerca volvulus 0.0015 0.0008 0.032
Echinococcus multilocularis Smad4 0.0008 0.0001 0.0001
Brugia malayi Doublecortin family protein 0.0023 0.0017 0.0165
Trypanosoma cruzi multidrug resistance-associated protein, putative 0.0044 0.004 0.0116
Leishmania major glucose transporter, lmgt3 0.0032 0.0027 0.0072
Onchocerca volvulus 0.0042 0.0038 0.1497
Echinococcus granulosus lysyl tRNA synthetase 0.0023 0.0017 0.0017
Trichomonas vaginalis PIKK family atypical protein kinase 0.0937 0.1018 1
Schistosoma mansoni regulator of G protein signaling 0.001 0.0003 0.0032
Trypanosoma brucei glucose transporter, putative 0.0032 0.0027 0.026
Trypanosoma brucei glucose transporter, putative 0.0032 0.0027 0.026
Trypanosoma cruzi multidrug resistance protein E, putative 0.0044 0.004 0.0116
Brugia malayi Cam kinase protein 1 0.0032 0.0027 0.0264
Mycobacterium tuberculosis Probable conserved integral membrane transport protein 0.0015 0.0008 0.0255
Loa Loa (eye worm) GTP-binding regulatory protein Gs alpha-S chain 0.0053 0.005 0.049
Leishmania major ATP-binding cassette protein subfamily B, member 1, putative 0.0044 0.004 0.0107
Trichomonas vaginalis sugar transporter, putative 0.0015 0.0008 0.0079
Echinococcus granulosus segment polarity protein dishevelled 0.001 0.0003 0.0003
Brugia malayi beta-lactamase 0.0042 0.0038 0.0369
Entamoeba histolytica P-glycoprotein 6, putative 0.0044 0.004 0.0394
Plasmodium falciparum protein kinase 6 0.0441 0.0475 1
Echinococcus multilocularis ecdysone induced protein 78C 0.001 0.0003 0.0003
Trichomonas vaginalis ATP-binding cassette transporter, putative 0.014 0.0146 0.1431
Trichomonas vaginalis phosphatidylinositol kinase, putative 0.018 0.0189 0.1861
Brugia malayi ABC transporter 0.0044 0.004 0.0394
Trichomonas vaginalis PIKK family atypical protein kinase 0.0937 0.1018 1
Loa Loa (eye worm) hypothetical protein 0.0042 0.0038 0.0378
Trichomonas vaginalis sugar transporter, putative 0.0015 0.0008 0.0079
Echinococcus granulosus Smad4 0.0008 0.0001 0.0001
Schistosoma mansoni hypothetical protein 0.0104 0.0106 0.1039
Brugia malayi Ligand-binding domain of nuclear hormone receptor family protein 0.001 0.0003 0.003
Schistosoma mansoni multidrug resistance protein 0.0044 0.004 0.0394
Entamoeba histolytica hypothetical protein 0.0041 0.0037 0.0366
Brugia malayi AMP-binding enzyme family protein 0.0008 0.0001 0.0008
Loa Loa (eye worm) beta-LACTamase domain containing family member 0.0042 0.0038 0.0369
Plasmodium vivax JmjC domain containing protein 0.0009 0.0002 0.0031
Echinococcus multilocularis phd:f box containing protein 0.0009 0.0002 0.0002
Mycobacterium ulcerans lipase LipD 0.0042 0.0038 0.9345
Brugia malayi Nuclear hormone receptor family member nhr-19 0.001 0.0003 0.003
Echinococcus multilocularis survival motor neuron protein 1 0.0236 0.025 0.025
Loa Loa (eye worm) nuclear hormone receptor family member nhr-49 0.001 0.0003 0.003
Echinococcus multilocularis JmjC domain containing protein 4 0.0009 0.0002 0.0002
Toxoplasma gondii prolyl-tRNA synthetase (ProRS) 0.0036 0.0032 0.0305
Plasmodium falciparum calcium-dependent protein kinase 4 0.0032 0.0027 0.055
Echinococcus granulosus solute carrier family 2 facilitated glucose 0.0104 0.0106 0.0106
Trichomonas vaginalis sugar transporter, putative 0.0015 0.0008 0.0079
Echinococcus granulosus solute carrier family 22 0.0015 0.0008 0.0008
Plasmodium vivax ABC transporter B family member 6, putative 0.0044 0.004 0.0829
Trypanosoma brucei lysyl-tRNA synthetase, putative 0.0023 0.0017 0.0163
Loa Loa (eye worm) hypothetical protein 0.0009 0.0002 0.0024
Echinococcus granulosus phosphatidylinositol 3 and 4 kinase 0.0937 0.1018 0.1018
Toxoplasma gondii histone lysine methyltransferase SET/SUV39 0.003 0.0025 0.0234
Loa Loa (eye worm) oxidoreductase 0.0008 0.0001 0.0008
Mycobacterium ulcerans fatty-acid-CoA ligase 0.0027 0.0022 0.5388
Echinococcus multilocularis solute carrier family 2 facilitated glucose 0.0104 0.0106 0.0106
Trichomonas vaginalis conserved hypothetical protein 0.0589 0.0637 0.6255
Loa Loa (eye worm) phosphatidylinositol 3 0.018 0.0189 0.1861
Trypanosoma brucei JmjC domain, hydroxylase, putative 0.0009 0.0002 0.0015
Loa Loa (eye worm) phosphatidylinositol 3 0.018 0.0189 0.1861
Onchocerca volvulus Steroid hormone receptor family member cnr14 homolog 0.001 0.0003 0.0122
Trichomonas vaginalis PIKK family atypical protein kinase 0.0937 0.1018 1
Onchocerca volvulus 0.0008 0.0001 0.0033
Trichomonas vaginalis myo-inositol transporter, putative 0.0015 0.0008 0.0079
Loa Loa (eye worm) nuclear hormone receptor family member nhr-40 0.001 0.0003 0.003
Trypanosoma brucei glucose transporter, putative 0.0032 0.0027 0.026
Echinococcus granulosus multidrug resistance associated protein 1 0.0044 0.004 0.004
Echinococcus multilocularis inositol monophosphatase 1 0.0037 0.0032 0.0032
Schistosoma mansoni FTZ-F1 nuclear receptor-like protein 0.001 0.0003 0.003
Loa Loa (eye worm) nuclear hormone receptor family member nhr-14 0.001 0.0003 0.003
Echinococcus granulosus Nuclear hormone receptor family member nhr 41 0.001 0.0003 0.0003
Trichomonas vaginalis PIKK family atypical protein kinase 0.0528 0.0571 0.5606
Loa Loa (eye worm) hypothetical protein 0.0042 0.0038 0.0369
Plasmodium falciparum acyl-CoA synthetase 0.002 0.0014 0.0287
Mycobacterium tuberculosis Conserved protein 0.0042 0.0038 0.1302
Trichomonas vaginalis ATP-binding cassette transporter, putative 0.014 0.0146 0.1431
Echinococcus multilocularis acetyl coenzyme A synthetase, cytoplasmic 0.0008 0.0001 0.0001
Echinococcus granulosus 5'partial|histone lysine N methyltransferase SETDB2 0.0029 0.0023 0.0023
Onchocerca volvulus 0.018 0.0189 0.7554
Leishmania major pentamidine resistance protein 1 0.0044 0.004 0.0107
Toxoplasma gondii sugar transporter ST3 0.0015 0.0008 0.0071
Leishmania major ATP-binding cassette protein subfamily C, member 6, putative 0.0044 0.004 0.0107
Brugia malayi AMP-binding enzyme family protein 0.0008 0.0001 0.0008
Loa Loa (eye worm) hypothetical protein 0.0029 0.0024 0.0235
Schistosoma mansoni multidrug resistance protein 0.014 0.0146 0.1431
Echinococcus granulosus ATP binding cassette subfamily B MDR:TAP 0.014 0.0146 0.0146
Trichomonas vaginalis phosphatidylinositol 3-kinase catalytic subunit alpha, beta, delta, putative 0.018 0.0189 0.1861
Trypanosoma cruzi long-chain-fatty-acid-CoA ligase, putative 0.0008 0.0001 0.0002
Trichomonas vaginalis phosphatidylinositol kinase, putative 0.018 0.0189 0.1861
Echinococcus granulosus JmjC domain containing protein 4 0.0009 0.0002 0.0002
Plasmodium falciparum multidrug resistance-associated protein 1 0.0044 0.004 0.0829
Mycobacterium ulcerans transmembrane ABC transporter ATP-binding protein 0.0044 0.004 1
Brugia malayi beta-lactamase family protein 0.0042 0.0038 0.0369
Trypanosoma cruzi phosphatidylinositol 3-kinase 2, putative 0.018 0.0189 0.0546
Plasmodium vivax phosphatidylinositol 4-kinase, putative 0.018 0.0189 0.3978
Giardia lamblia Multidrug resistance-associated protein 1 0.0044 0.004 0.0318
Plasmodium falciparum calcium-dependent protein kinase 5 0.0032 0.0027 0.055
Entamoeba histolytica P-glycoprotein-5 0.014 0.0146 0.1431
Trichomonas vaginalis phosphatidylinositol 3-kinase catalytic subunit alpha, beta, delta, putative 0.018 0.0189 0.1861
Trichomonas vaginalis PIKK family atypical protein kinase 0.0937 0.1018 1
Brugia malayi hypothetical protein 0.0023 0.0017 0.0165
Mycobacterium ulcerans esterase/lipase LipP 0.0042 0.0038 0.9345
Mycobacterium ulcerans fusion protein of transposase for IS2606 and sialic acid-transport integral membrane protein NanT 0.0015 0.0008 0.1832
Trypanosoma cruzi phosphatidylinositol 3-kinase, putative 0.018 0.0189 0.0546
Loa Loa (eye worm) hypothetical protein 0.001 0.0003 0.003
Trichomonas vaginalis PIKK family atypical protein kinase 0.0937 0.1018 1
Trypanosoma brucei glucose transporter 2A 0.0032 0.0027 0.026
Echinococcus granulosus FKBP12 rapamycin complex associated protein 0.0937 0.1018 0.1018
Trypanosoma cruzi hypothetical protein, conserved 0.0042 0.0038 0.0108
Schistosoma mansoni jumonji/arid domain-containing protein 0.0035 0.0031 0.03
Trichomonas vaginalis PIKK family atypical protein kinase 0.0937 0.1018 1
Trypanosoma brucei phosphatidylinositol 3-kinase tor, putative 0.018 0.0189 0.1854
Plasmodium falciparum phosphatidylinositol 3-kinase 0.018 0.0189 0.3978
Toxoplasma gondii calcium-dependent protein kinase CDPK2B 0.0032 0.0027 0.0256
Entamoeba histolytica ATP-binding cassette protein, putative 0.0044 0.004 0.0394
Loa Loa (eye worm) PHD-finger family protein 0.0029 0.0024 0.0235
Mycobacterium ulcerans acyl-CoA synthetase 0.0027 0.0022 0.5388
Echinococcus multilocularis nuclear receptor 2DBD gamma 0.001 0.0003 0.0003
Trypanosoma cruzi phosphatidylinositol 4-kinase, putative 0.018 0.0189 0.0546
Brugia malayi Phosphatidylinositol 3- and 4-kinase family protein 0.0937 0.1018 1
Giardia lamblia Phosphatidylinositol 4-kinase 0.018 0.0189 0.1796
Echinococcus granulosus jumonji domain containing protein 0.004 0.0036 0.0036
Schistosoma mansoni hypothetical protein 0.0041 0.0037 0.0366
Trichomonas vaginalis phosphatidylinositol 3-kinase class, putative 0.018 0.0189 0.1861
Schistosoma mansoni mixed-lineage leukemia protein mll 0.0011 0.0004 0.0036
Onchocerca volvulus 0.003 0.0025 0.0982
Echinococcus multilocularis phosphatidylinositol 4 phosphate 3 kinase C2 0.018 0.0189 0.0189
Echinococcus granulosus smad 0.0008 0.0001 0.0001
Trypanosoma cruzi phosphatidylinositol kinase, putative 0.018 0.0189 0.0546
Brugia malayi Phosphatidylinositol 3- and 4-kinase family protein 0.0528 0.0571 0.5606
Giardia lamblia Phosphoinositide-3-kinase, class 3 0.018 0.0189 0.1796
Loa Loa (eye worm) hypothetical protein 0.0023 0.0017 0.0165
Loa Loa (eye worm) hypothetical protein 0.0589 0.0637 0.6255
Entamoeba histolytica hypothetical protein 0.0041 0.0037 0.0366
Plasmodium vivax phosphatidylinositol 3-kinase, putative 0.018 0.0189 0.3978
Loa Loa (eye worm) major facilitator superfamily transporter 0.0015 0.0008 0.0079
Echinococcus multilocularis lysyl tRNA synthetase 0.0023 0.0017 0.0017
Trypanosoma cruzi phosphatidylinositol 3-kinase 2, putative 0.018 0.0189 0.0546
Trichomonas vaginalis PIKK family atypical protein kinase 0.0937 0.1018 1
Trypanosoma cruzi sugar transporter, putative 0.0015 0.0008 0.0023
Brugia malayi PHD-finger family protein 0.0009 0.0002 0.0024
Onchocerca volvulus Protein ultraspiracle homolog 0.001 0.0003 0.0122
Brugia malayi ABC transporter family protein 0.014 0.0146 0.1431
Plasmodium vivax multidrug resistance protein 2, putative 0.0044 0.004 0.0829
Echinococcus multilocularis lysine specific demethylase 5A 0.0035 0.0031 0.0031
Schistosoma mansoni jumonji domain containing protein 0.0076 0.0075 0.0736
Schistosoma mansoni sugar transporter 0.0015 0.0008 0.0079
Trypanosoma cruzi hypothetical protein, conserved 0.3174 0.347 1
Plasmodium falciparum ABC transporter B family member 3, putative 0.0044 0.004 0.0829
Echinococcus multilocularis Sugar transporter ERD6 protein 0.0015 0.0008 0.0008
Brugia malayi multidrug resistance protein 3 0.014 0.0146 0.1431
Trichomonas vaginalis PIKK family atypical protein kinase 0.0937 0.1018 1
Echinococcus granulosus Jumonji AT rich interactive domain 1B 0.0009 0.0002 0.0002
Brugia malayi Nuclear hormone receptor family member nhr-25 0.001 0.0003 0.003
Trichomonas vaginalis PIKK family atypical protein kinase 0.0937 0.1018 1
Loa Loa (eye worm) ABC transporter transmembrane region family protein 0.0044 0.004 0.0394
Schistosoma mansoni retinoic acid receptor RXR 0.001 0.0003 0.003
Plasmodium falciparum ABC transporter B family member 5, putative 0.0044 0.004 0.0829
Trypanosoma brucei THT1 - hexose transporter, putative 0.0032 0.0027 0.026
Leishmania major phosphatidylinositol kinase related protein, putative 0.0427 0.046 0.1251
Leishmania major phosphatidylinositol kinase, putative 0.018 0.0189 0.0515
Leishmania major phosphatidylinositol 3-related kinase, putative 0.0937 0.1018 0.2775
Mycobacterium ulcerans sugar-transport integral membrane protein SugI 0.0015 0.0008 0.1832
Echinococcus granulosus lysine specific demethylase 5A 0.0035 0.0031 0.0031
Schistosoma mansoni multidrug resistance protein 0.0044 0.004 0.0394
Trichomonas vaginalis sugar transporter, putative 0.0015 0.0008 0.0079
Onchocerca volvulus Alhambra homolog 0.0029 0.0024 0.0952
Trypanosoma brucei phosphatidylinositol 3-kinase, putative 0.018 0.0189 0.1854
Echinococcus multilocularis Polycystic kidney disease protein 0.0023 0.0017 0.0017
Loa Loa (eye worm) ABC transporter 0.0044 0.004 0.0394
Mycobacterium leprae Probable lysyl-tRNA synthase LysS (lysine--tRNA ligase 1) (LysRS 1) (lysine translase) 0.002 0.0014 0.0677
Echinococcus granulosus regulator of G protein signaling 7 0.001 0.0003 0.0003
Trichomonas vaginalis multidrug resistance protein 1, 2, putative 0.014 0.0146 0.1431
Trypanosoma cruzi hexose transporter, putative 0.0018 0.0011 0.0033
Trypanosoma brucei Phosphatidylinositol 3-kinase tor1 0.0937 0.1018 1
Loa Loa (eye worm) hypothetical protein 0.005 0.0047 0.0458
Echinococcus multilocularis solute carrier family 2 facilitated glucose 0.0104 0.0106 0.0106
Trypanosoma cruzi ABC transporter, mitochondrial, putative 0.0044 0.004 0.0116
Schistosoma mansoni hypothetical protein 0.0023 0.0017 0.0165
Mycobacterium leprae conserved hypothetical protein 0.0042 0.0038 0.1947
Mycobacterium ulcerans long-chain-fatty-acid-CoA ligase 0.0027 0.0022 0.5388
Loa Loa (eye worm) calcium/calmodulin-dependent protein kinase ID 0.0032 0.0027 0.0264
Entamoeba histolytica hypothetical protein 0.0041 0.0037 0.0366
Onchocerca volvulus 0.0027 0.0022 0.0877
Brugia malayi ecdysteroid receptor 0.001 0.0003 0.003
Echinococcus multilocularis smad 0.0008 0.0001 0.0001
Schistosoma mansoni Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) 0.0053 0.005 0.049
Plasmodium vivax calcium-dependent protein kinase 3, putative 0.0032 0.0027 0.055
Trichomonas vaginalis phosphatidylinositol kinase, putative 0.018 0.0189 0.1861
Plasmodium vivax calcium-dependent protein kinase 1, putative 0.0032 0.0027 0.055
Trichomonas vaginalis sugar transporter, putative 0.0015 0.0008 0.0079
Entamoeba histolytica phosphatidylinositol 4-kinase, putative 0.018 0.0189 0.1861
Plasmodium falciparum JmjC domain-containing protein, putative 0.0009 0.0002 0.0031
Entamoeba histolytica P-glycoprotein 5, putative 0.014 0.0146 0.1431
Echinococcus granulosus ATP binding cassette subfamily B MDR:TAP 0.014 0.0146 0.0146
Mycobacterium leprae PROBABLE DRUGS-TRANSPORT TRANSMEMBRANE ATP-BINDING PROTEIN ABC TRANSPORTER 0.0044 0.004 0.2083
Giardia lamblia GTOR 0.0937 0.1018 1
Trichomonas vaginalis conserved hypothetical protein 0.0032 0.0027 0.0268
Entamoeba histolytica P-glycoprotein 5, putative 0.0042 0.0038 0.0378
Trichomonas vaginalis sugar transporter, putative 0.0015 0.0008 0.0079
Entamoeba histolytica hypothetical protein 0.0044 0.004 0.0394
Giardia lamblia Multidrug resistance-associated protein 1 0.0044 0.004 0.0318
Trichomonas vaginalis lysyl-tRNA synthetase, putative 0.0023 0.0017 0.0171
Entamoeba histolytica ATP-binding cassette protein, putative 0.0044 0.004 0.0394
Leishmania major p-glycoprotein 0.014 0.0146 0.0395
Schistosoma mansoni fyve finger-containing phosphoinositide kinase fyv1 0.001 0.0003 0.0032
Loa Loa (eye worm) hypothetical protein 0.0015 0.0008 0.0079
Trypanosoma cruzi phosphatidylinositol kinase related protein, putative 0.0594 0.0643 0.1854
Echinococcus multilocularis lipoxygenase domain containing protein 0.0023 0.0017 0.0017
Loa Loa (eye worm) hypothetical protein 0.002 0.0014 0.0142
Trichomonas vaginalis sugar transporter, putative 0.0015 0.0008 0.0079
Plasmodium vivax hypothetical protein, conserved 0.0029 0.0024 0.0486
Loa Loa (eye worm) ABC transporter 0.0044 0.004 0.0394
Chlamydia trachomatis acylglycerophosphoethanolamine acyltransferase 0.002 0.0014 0.073
Echinococcus multilocularis beta LACTamase domain containing family member 0.0042 0.0038 0.0038
Trichomonas vaginalis PIKK family atypical protein kinase 0.0937 0.1018 1
Brugia malayi Pre-SET motif family protein 0.003 0.0025 0.0242
Echinococcus granulosus Phosphatidylinositol 4 kinase type 2 beta 0.018 0.0189 0.0189
Brugia malayi nuclear hormone receptor 0.001 0.0003 0.003
Trichomonas vaginalis ABC transporter, half transporter, putative 0.014 0.0146 0.1431
Mycobacterium ulcerans extragenic suppressor protein SuhB 0.0037 0.0032 0.8029
Toxoplasma gondii non-specific serine/threonine protein kinase 0.0589 0.0637 0.6252
Toxoplasma gondii hypothetical protein 0.001 0.0003 0.0023
Schistosoma mansoni hypothetical protein 0.0048 0.0045 0.0439
Trypanosoma brucei phosphatidylinositol 3-related kinase, putative 0.0937 0.1018 1
Plasmodium falciparum proline--tRNA ligase 0.0036 0.0032 0.0654
Trypanosoma cruzi phosphatidylinositol 3-kinase, putative 0.0528 0.0571 0.1645
Toxoplasma gondii sugar transporter ST1 0.0015 0.0008 0.0071
Toxoplasma gondii transporter, major facilitator family protein 0.0015 0.0008 0.0071
Trichomonas vaginalis PIKK family atypical protein kinase 0.0937 0.1018 1
Mycobacterium ulcerans fusion of enoyl-CoA hydratase, EchA21 and lipase, LipE 0.0042 0.0038 0.9345
Echinococcus multilocularis FKBP12 rapamycin complex associated protein 0.0937 0.1018 0.1018
Brugia malayi ABC transporter transmembrane region family protein 0.0044 0.004 0.0394
Echinococcus multilocularis histone lysine N methyltransferase SETMAR 0.003 0.0025 0.0025
Loa Loa (eye worm) phosphatidylinositol 4-kinase type 3 alpha isoform 1 0.018 0.0189 0.1861
Schistosoma mansoni hypothetical protein 0.0186 0.0195 0.1918
Trichomonas vaginalis abcb9, putative 0.014 0.0146 0.1431
Echinococcus granulosus calcium dependent protein kinase 0.003 0.0025 0.0025
Echinococcus multilocularis gcn5proteinral control of amino acid synthesis 0.0166 0.0174 0.0174
Trypanosoma cruzi JmjC domain, hydroxylase, putative 0.0009 0.0002 0.0007
Echinococcus multilocularis arachidonate 5 lipoxygenase 0.0135 0.014 0.014
Mycobacterium tuberculosis Probable drugs-transport transmembrane ATP-binding protein ABC transporter 0.0044 0.004 0.1393
Trichomonas vaginalis D-aminoacylase, putative 0.0042 0.0038 0.0369
Mycobacterium tuberculosis Probable fatty-acid-CoA ligase FadD5 (fatty-acid-CoA synthetase) (fatty-acid-CoA synthase) 0.0019 0.0013 0.0439
Plasmodium falciparum histone acetyltransferase GCN5 0.0045 0.0041 0.0851
Echinococcus granulosus multidrug resistance protein 1 0.0098 0.0099 0.0099
Echinococcus granulosus phosphatidylinositol 4 kinase alpha 0.018 0.0189 0.0189
Trichomonas vaginalis PIKK family atypical protein kinase 0.0937 0.1018 1
Mycobacterium tuberculosis Probable lipase LipD 0.0042 0.0038 0.1302
Trichomonas vaginalis penicillin-binding protein, putative 0.0042 0.0038 0.0369
Brugia malayi Nuclear hormone receptor family member nhr-14 0.001 0.0003 0.003
Brugia malayi hypothetical protein 0.0023 0.0017 0.0165
Echinococcus multilocularis Nuclear hormone receptor family member nhr 41 0.001 0.0003 0.0003
Trichomonas vaginalis set domain proteins, putative 0.0236 0.0251 0.2463
Loa Loa (eye worm) hypothetical protein 0.0408 0.044 0.4316
Echinococcus granulosus serine:threonine protein kinase SMG1 0.0528 0.0571 0.0571
Trichomonas vaginalis phosphatidylinositol 3-kinase catalytic subunit gamma, putative 0.018 0.0189 0.1861
Echinococcus multilocularis ATP binding cassette subfamily B (MDR:TAP) 0.014 0.0146 0.0146
Brugia malayi hypothetical protein 0.0015 0.0008 0.0079
Echinococcus multilocularis solute carrier family 2 facilitated glucose 0.0104 0.0106 0.0106
Schistosoma mansoni nuclear hormone receptor 0.001 0.0003 0.003
Schistosoma mansoni smdr2 0.014 0.0146 0.1431
Echinococcus granulosus PHD finger protein rhinoceros 0.0029 0.0024 0.0024
Toxoplasma gondii ATP-binding cassette sub-family B member 5 0.0044 0.004 0.0386
Mycobacterium ulcerans fatty-acid-CoA ligase 0.002 0.0014 0.346
Brugia malayi phosphatidylinositol 4-kinase, catalytic, alpha polypeptide 0.018 0.0189 0.1861
Entamoeba histolytica acetyltransferase, GNAT family 0.0045 0.0041 0.0405
Brugia malayi Steroid receptor seven-up type 2 0.001 0.0003 0.003
Echinococcus multilocularis mothers against decapentaplegic 5 0.0008 0.0001 0.0001
Echinococcus multilocularis solute carrier family 22 0.0015 0.0008 0.0008
Schistosoma mansoni smad1 5 8 and 0.0008 0.0001 0.0009
Loa Loa (eye worm) hypothetical protein 0.0027 0.0022 0.0216
Giardia lamblia Prolyl-tRNA synthetase 0.0031 0.0026 0.018
Loa Loa (eye worm) hypothetical protein 0.0015 0.0008 0.0079
Loa Loa (eye worm) MH1 domain-containing protein 0.0008 0.0001 0.0009
Brugia malayi Nuclear hormone receptor family member nhr-1 0.001 0.0003 0.003
Schistosoma mansoni dishevelled 0.001 0.0003 0.0032
Brugia malayi FAT domain containing protein 0.0408 0.044 0.4316
Entamoeba histolytica FKBP-rapamycin associated protein (FRAP), putative 0.0937 0.1018 1
Onchocerca volvulus 0.001 0.0003 0.0122
Trichomonas vaginalis sugar transporter, putative 0.0015 0.0008 0.0079
Toxoplasma gondii phosphatidylinositol 3- and 4-kinase 0.018 0.0189 0.1854
Schistosoma mansoni phosphatidylinositol 4-kinase 0.018 0.0189 0.1861
Entamoeba histolytica acyl-CoA synthetase, putative 0.0027 0.0022 0.0216
Trichomonas vaginalis D-aminoacylase, putative 0.0042 0.0038 0.0369
Trypanosoma cruzi hexose transporter 0.0032 0.0027 0.0079
Echinococcus multilocularis Phosphatidylinositol 4 kinase type 2 beta 0.018 0.0189 0.0189
Echinococcus granulosus guanine nucleotide binding protein Gs subunit 0.0053 0.005 0.005
Leishmania major 4-coumarate:coa ligase-like protein 0.0027 0.0022 0.0058
Mycobacterium leprae Probable lipase LipE 0.0042 0.0038 0.1947
Trichomonas vaginalis lipid A export ATP-binding/permease protein msba, putative 0.014 0.0146 0.1431
Loa Loa (eye worm) AMP-binding enzyme family protein 0.0008 0.0001 0.0008
Trichomonas vaginalis cat eye syndrome critical region protein 2, cscr2, putative 0.0049 0.0046 0.0448
Mycobacterium tuberculosis Iron-regulated transporter IrtA 0.0044 0.004 0.1393
Loa Loa (eye worm) hypothetical protein 0.0031 0.0026 0.0257
Schistosoma mansoni glucose transport protein 0.0104 0.0106 0.1039
Loa Loa (eye worm) hypothetical protein 0.0027 0.0022 0.0216
Echinococcus multilocularis microtubule associated protein 2 0.0688 0.0746 0.0746
Brugia malayi DIX domain containing protein 0.001 0.0003 0.0032
Plasmodium vivax multidrug resistance protein 1, putative 0.014 0.0146 0.3056
Loa Loa (eye worm) hypothetical protein 0.018 0.0189 0.1861
Echinococcus multilocularis 0.018 0.0189 0.0189
Trichomonas vaginalis ABC transporter, putative 0.014 0.0146 0.1431
Trichomonas vaginalis ABC transporter, putative 0.014 0.0146 0.1431
Trypanosoma cruzi hexose transporter, putative 0.0032 0.0027 0.0079
Entamoeba histolytica multidrug resistance protein, putative 0.0044 0.004 0.0394
Loa Loa (eye worm) sugar transporter 0.0104 0.0106 0.1039
Schistosoma mansoni smad 0.0008 0.0001 0.0009
Loa Loa (eye worm) hypothetical protein 0.001 0.0003 0.003
Toxoplasma gondii ATP-binding cassette transporter ABC.B1 0.014 0.0146 0.1424
Onchocerca volvulus 0.0015 0.0008 0.032
Loa Loa (eye worm) hypothetical protein 0.0025 0.002 0.0194
Loa Loa (eye worm) hypothetical protein 0.0027 0.0022 0.0216
Schistosoma mansoni sugar transporter 0.0015 0.0008 0.0079
Mycobacterium leprae conserved hypothetical protein 0.018 0.0189 1
Echinococcus multilocularis synaptic vesicle 2 protein 0.0015 0.0008 0.0008
Echinococcus granulosus histone acetyltransferase KAT2B 0.0049 0.0046 0.0046
Brugia malayi ABC transporter family protein 0.0044 0.004 0.0394
Echinococcus multilocularis serine protein kinase ATM 0.0775 0.0841 0.0841
Echinococcus granulosus segment polarity protein dishevelled 0.001 0.0003 0.0003
Entamoeba histolytica phosphatidylinositol 3-kinase, putative 0.018 0.0189 0.1861
Loa Loa (eye worm) phosphatidylinositol 3 0.018 0.0189 0.1861
Loa Loa (eye worm) MH2 domain-containing protein 0.0119 0.0122 0.1203
Brugia malayi MH2 domain containing protein 0.0008 0.0001 0.0009
Echinococcus granulosus Polycystic kidney disease protein 0.0023 0.0017 0.0017
Plasmodium vivax proline--tRNA ligase, putative 0.0036 0.0032 0.0654
Toxoplasma gondii PHD-finger domain-containing protein 0.0009 0.0002 0.0016
Trichomonas vaginalis sugar transporter, putative 0.0015 0.0008 0.0079
Brugia malayi Calcium/calmodulin-dependent protein kinase type II alpha chain 0.0032 0.0027 0.0264
Trypanosoma brucei PHD-zinc-finger like domain containing protein, putative 0.0009 0.0002 0.0016
Schistosoma mansoni Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) 0.0053 0.005 0.049
Trichomonas vaginalis glucose transporter, putative 0.0015 0.0008 0.0079
Loa Loa (eye worm) hypothetical protein 0.0015 0.0008 0.0079
Onchocerca volvulus 0.0042 0.0038 0.1497
Plasmodium falciparum multidrug resistance protein 2 0.0044 0.004 0.0829
Echinococcus multilocularis lysine specific demethylase 6a 0.0009 0.0002 0.0002
Schistosoma mansoni family S12 unassigned peptidase (S12 family) 0.0042 0.0038 0.0369
Echinococcus granulosus guanine nucleotide binding protein Gs subunit 0.0053 0.005 0.005
Echinococcus multilocularis Basic leucine zipper (bZIP) transcription 0.0041 0.0037 0.0037
Loa Loa (eye worm) hypothetical protein 0.0042 0.0038 0.0369
Plasmodium vivax histone acetyltransferase GCN5, putative 0.0049 0.0046 0.0946
Entamoeba histolytica hypothetical protein 0.018 0.0189 0.1861
Entamoeba histolytica P-glycoprotein 6, putative 0.0044 0.004 0.0394
Schistosoma mansoni histone-lysine n-methyltransferase setb1 0.003 0.0025 0.0242
Schistosoma mansoni phosphatidylinositol-45-bisphosphate 3-kinase catalytic subunit alpha PI3K 0.018 0.0189 0.1861
Brugia malayi AMP-binding enzyme family protein 0.0027 0.0022 0.0216
Echinococcus multilocularis jumonji domain containing 1A 0.0009 0.0002 0.0002
Echinococcus multilocularis solute carrier family 22 0.0015 0.0008 0.0008
Echinococcus granulosus nuclear receptor 2DBD gamma 0.001 0.0003 0.0003
Leishmania major myo-inositol/proton symporter (MIT) 0.0015 0.0008 0.002
Echinococcus granulosus lysine specific demethylase 6a 0.0009 0.0002 0.0002
Leishmania major 4-coumarate:coa ligase-like protein 0.0027 0.0022 0.0058
Mycobacterium tuberculosis Probable esterase/lipase LipP 0.0042 0.0038 0.1302
Trichomonas vaginalis lipid A export ATP-binding/permease protein msba, putative 0.014 0.0146 0.1431
Entamoeba histolytica hypothetical protein 0.018 0.0189 0.1861
Echinococcus granulosus Basic leucine zipper bZIP transcription 0.0041 0.0037 0.0037
Loa Loa (eye worm) steroid hormone receptor 0.001 0.0003 0.003
Mycobacterium ulcerans lysyl-tRNA synthetase 0.0023 0.0017 0.4225
Loa Loa (eye worm) hypothetical protein 0.0008 0.0001 0.0008
Brugia malayi jmjC domain containing protein 0.0009 0.0002 0.0023
Schistosoma mansoni gcn5proteinral control of amino-acid synthesis 5-like 2 gcnl2 0.0166 0.0174 0.1713
Brugia malayi regulator of G-protein signaling egl-10 0.001 0.0003 0.0032
Trichomonas vaginalis lipid A export ATP-binding/permease protein msba, putative 0.014 0.0146 0.1431
Wolbachia endosymbiont of Brugia malayi ABC-type protease secretion system, ATPase and permease component, AprD 0.0044 0.004 1
Loa Loa (eye worm) doublecortin family protein 0.0023 0.0017 0.0165
Trichomonas vaginalis conserved hypothetical protein 0.0032 0.0027 0.0268
Echinococcus granulosus TGF beta signal transducer SmadC 0.0008 0.0001 0.0001
Brugia malayi Domain found in Dishevelled, Egl-10, and Pleckstrin family protein 0.001 0.0003 0.0032
Echinococcus multilocularis calcium:calmodulin dependent protein kinase type 0.0032 0.0027 0.0027
Trypanosoma cruzi phosphatidylinositol 3-related kinase, putative 0.0937 0.1018 0.2935
Trypanosoma brucei hypothetical protein, conserved 0.0042 0.0038 0.0361
Mycobacterium ulcerans prolyl-tRNA synthetase 0.0011 0.0004 0.0829
Loa Loa (eye worm) multidrug resistance protein 3 0.014 0.0146 0.1431
Schistosoma mansoni loxhd1 0.0023 0.0017 0.0165
Echinococcus granulosus retinoic acid receptor rxr beta a 0.001 0.0003 0.0003
Trichomonas vaginalis PIKK family atypical protein kinase 0.018 0.0189 0.1861
Loa Loa (eye worm) hypothetical protein 0.014 0.0146 0.1431
Echinococcus multilocularis DNA dependent protein kinase catalytic subunit 0.9132 1 1
Loa Loa (eye worm) beta-lactamase 0.0042 0.0038 0.0369
Schistosoma mansoni histone-lysine n-methyltransferase suv9 0.003 0.0025 0.0242
Plasmodium vivax ABC transporter B family member 5, putative 0.0044 0.004 0.0829
Entamoeba histolytica P-glycoprotein-2, putative 0.014 0.0146 0.1431
Loa Loa (eye worm) hypothetical protein 0.0015 0.0008 0.0079
Trichomonas vaginalis conserved hypothetical protein 0.0015 0.0008 0.0079
Loa Loa (eye worm) hypothetical protein 0.014 0.0146 0.1431
Trichomonas vaginalis ATP-binding cassette transporter, putative 0.0042 0.0038 0.0378
Trichomonas vaginalis sugar transporter, putative 0.0015 0.0008 0.0079
Plasmodium vivax ABC transporter B family member 3, putative 0.0044 0.004 0.0829
Trypanosoma cruzi myo-inositol-1(or 4)-monophosphatase 1, putative 0.0037 0.0032 0.0093
Leishmania major prolyl-tRNA synthetase, putative,bifunctional aminoacyl-tRNA synthetase, putative 0.0036 0.0032 0.0085
Brugia malayi Nuclear hormone receptor family member nhr-31 0.001 0.0003 0.003
Echinococcus granulosus survival motor neuron protein 1 0.0236 0.025 0.025
Trypanosoma cruzi acetyl-CoA synthetase, putative 0.0008 0.0001 0.0002
Trichomonas vaginalis sugar transporter, putative 0.0015 0.0008 0.0079
Entamoeba histolytica phosphatidylinositol 3-kinase, putative 0.018 0.0189 0.1861
Schistosoma mansoni ataxia telangiectasia mutated (atm)-related 0.0937 0.1018 1
Trichomonas vaginalis abcb9, putative 0.014 0.0146 0.1431
Onchocerca volvulus 0.0015 0.0008 0.032
Loa Loa (eye worm) phosphatidylinositol 3 0.0937 0.1018 1
Trypanosoma brucei phosphatidylinositol 4-kinase, putative 0.018 0.0189 0.1854
Schistosoma mansoni steroid hormone receptor ad4bp 0.001 0.0003 0.003
Brugia malayi Sugar transporter family protein 0.0015 0.0008 0.0079
Trypanosoma cruzi acetyl-CoA synthetase, putative 0.0008 0.0001 0.0002
Mycobacterium ulcerans beta-lactamase 0.0042 0.0038 0.9345
Trypanosoma brucei target of rapamycin kinase 3, putative 0.0937 0.1018 1
Loa Loa (eye worm) sugar transporter 0.0015 0.0008 0.0079
Schistosoma mansoni thyroid hormone receptor 0.001 0.0003 0.003
Loa Loa (eye worm) G protein signaling regulator EGL-10 0.001 0.0003 0.0032
Brugia malayi multidrug Resistance Protein family member (mrp-5), putative 0.0044 0.004 0.0394
Schistosoma mansoni phosphatidylinositol 3-and 4-kinase 0.0937 0.1018 1
Brugia malayi N-terminal motif family protein 0.0207 0.0219 0.2153
Giardia lamblia MRP-like ABC transporter 0.0044 0.004 0.0318
Echinococcus multilocularis 0.0044 0.004 0.004
Schistosoma mansoni smad1 5 8 and 0.0008 0.0001 0.0009
Echinococcus multilocularis solute carrier family 22 0.0015 0.0008 0.0008
Loa Loa (eye worm) hypothetical protein 0.0015 0.0008 0.0079
Echinococcus granulosus ATP binding cassette subfamily B MDR:TAP 0.014 0.0146 0.0146
Trichomonas vaginalis sugar transporter, putative 0.0015 0.0008 0.0079
Echinococcus multilocularis multidrug resistance associated protein 7 0.0044 0.004 0.004
Brugia malayi MH1 domain containing protein 0.0008 0.0001 0.0009
Plasmodium falciparum multidrug resistance protein 1 0.014 0.0146 0.3056
Brugia malayi Phosphatidylinositol 3- and 4-kinase family protein 0.018 0.0189 0.1861
Echinococcus multilocularis FTZ F1 nuclear receptor protein 0.001 0.0003 0.0003
Trichomonas vaginalis PIKK family atypical protein kinase 0.018 0.0189 0.1861
Brugia malayi Phosphatidylinositol 3- and 4-kinase family protein 0.018 0.0189 0.1861
Leishmania major ATP-binding cassette protein subfamily C, member 1, putative 0.0044 0.004 0.0107

Activities

No activities found for this compound.

Phenotypes

Whole-cell/tissue/organism interactions

We have no records of whole-cell/tissue assays done with this compound What does this mean?

Many chemical entities in TDR Targets come from high-throughput screenings with whole cells or tissue samples, and not all assayed compounds have been tested against a single a single target protein, probably because they get ruled out during screening process. Even if these compounds may have not been of interest in the original screening, they may come as interesting leads for other screening assays. Furthermore, we may be able to propose drug-target associations using chemical similarities and network patterns.

Annotated phenotypes:

We have no manually annotated phenotypes for this drug. What does this mean? / Care to help?
In TDR Targets, information about phenotypes that are caused by drugs, or by genetic manipulation of cells (e.g. gene knockouts or knockdowns) is manually curated from the literature. These descriptions help to describe the potential of the target for drug development. If no information is available for this gene or if the information is incomplete, this may mean that i) the papers containing this information either appeared after the curation effort for this organism was carried out or they were inadvertently missed by curators; or that ii) the curation effort for this organism has not yet started.
 
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External resources for this compound

Bibliographic References

No literature references available for this target.

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