Detailed information for compound 440858

Basic information

Technical information
  • Name: Unnamed compound
  • MW: 378.895 | Formula: C23H23ClN2O
  • H donors: 1 H acceptors: 1 LogP: 5.16 Rotable bonds: 5
    Rule of 5 violations (Lipinski): 1
  • SMILES: Clc1cccc(c1)CN1CCC(CC1)NC(=O)c1cccc2c1cccc2
  • InChi: 1S/C23H23ClN2O/c24-19-8-3-5-17(15-19)16-26-13-11-20(12-14-26)25-23(27)22-10-4-7-18-6-1-2-9-21(18)22/h1-10,15,20H,11-14,16H2,(H,25,27)
  • InChiKey: OSZCDLPLSILDJI-UHFFFAOYSA-N  


Substructure search Similarity search

Network

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Synonyms

No synonyms found for this compound

Targets

Known targets for this compound

Species Target name Source Bibliographic reference
Homo sapiens dopamine receptor D4 Starlite/ChEMBL References

Predicted pathogen targets for this compound

By orthology
No druggable targets predicted by orthology data
By sequence similarity to non orthologous known druggable targets
No druggable targets predicted by sequence similarity
Obtained from network model

Ranking Plot

Putative Targets List

Species Potential target Raw Global Species
Brugia malayi Variant SH3 domain containing protein 0.045 0.022 0.0217
Brugia malayi serine/threonine-protein kinase PAK 7 0.1407 0.1673 0.167
Brugia malayi Fes/CIP4 homology domain containing protein 0.0496 0.0291 0.0287
Trichomonas vaginalis CAMK family protein kinase 0.0451 0.0222 0.1003
Echinococcus multilocularis basement membrane specific heparan sulfate 0.0676 0.0564 0.0721
Echinococcus multilocularis expressed conserved protein 0.0588 0.043 0.0542
Entamoeba histolytica protein kinase, putative 0.0432 0.0194 0.0777
Echinococcus granulosus tyrosine kinase 0.0536 0.0351 0.0357
Echinococcus multilocularis cyclin dependent kinase 5 0.0705 0.0607 0.078
Giardia lamblia Kinase, AGC AKT 0.0694 0.0591 0.2932
Entamoeba histolytica protein kinase, putative 0.073 0.0645 0.2872
Brugia malayi Immunoglobulin I-set domain containing protein 0.0341 0.0055 0.0051
Plasmodium falciparum cAMP-dependent protein kinase catalytic subunit 0.0545 0.0365 0.1943
Echinococcus granulosus receptor type tyrosine protein phosphatase 0.0396 0.0139 0.0124
Schistosoma mansoni septate junction protein 0.0341 0.0055 0.0097
Entamoeba histolytica protein kinase, putative 0.0726 0.064 0.2846
Echinococcus multilocularis Serine:threonine protein kinase PLK4 0.0866 0.0852 0.1109
Schistosoma mansoni diacylglycerol kinase theta 0.0322 0.0027 0.0043
Brugia malayi Protein kinase domain containing protein 0.1166 0.1307 0.1304
Echinococcus granulosus ribosomal protein s6 kinase beta 1 0.0958 0.0992 0.1064
Brugia malayi Protein kinase domain containing protein 0.1064 0.1152 0.1149
Loa Loa (eye worm) CK1/CK1/CK1-D protein kinase 0.0562 0.0391 0.0391
Schistosoma mansoni vam6/vps39 related 0.0429 0.0189 0.0351
Trichomonas vaginalis CAMK family protein kinase 0.0451 0.0222 0.1003
Schistosoma mansoni cell adhesion molecule 0.0396 0.0139 0.0257
Plasmodium vivax serine/threonine protein kinase KIN, putative 0.0451 0.0222 0.1109
Echinococcus granulosus calcium:calmodulin dependent protein kinase type 1 0.0498 0.0293 0.0294
Loa Loa (eye worm) TK/FER protein kinase 0.0536 0.0351 0.0351
Trichomonas vaginalis conserved hypothetical protein 0.0329 0.0037 0.0153
Echinococcus granulosus p21 activated protein kinase 1 Dpak1 0.0501 0.0299 0.03
Trypanosoma cruzi polo-like protein kinase, putative 0.1457 0.1749 1
Echinococcus multilocularis serine:threonine protein kinase N2 0.1488 0.1796 0.2377
Echinococcus multilocularis dual specificity 0.0726 0.064 0.0824
Loa Loa (eye worm) TK/FER protein kinase 0.0536 0.0351 0.0351
Echinococcus granulosus calcium activated potassium channel 0.0718 0.0628 0.0663
Trichomonas vaginalis CMGC family protein kinase 0.0487 0.0277 0.1257
Plasmodium vivax protein kinase Crk2 0.0705 0.0607 0.3849
Echinococcus granulosus protein kinase shaggy 0.0766 0.07 0.0743
Echinococcus granulosus neurotracting:lsamp:neurotrimin:obcam 0.085 0.0828 0.0883
Trichomonas vaginalis AGC family protein kinase 0.1275 0.1472 0.6745
Echinococcus multilocularis roundabout 2 0.1072 0.1165 0.1529
Echinococcus multilocularis CDC7 cell division cycle 7 0.0405 0.0152 0.0168
Echinococcus multilocularis nervana 2 0.0739 0.0659 0.0849
Loa Loa (eye worm) PLK/PLK1 protein kinase 0.1457 0.1749 0.1749
Trypanosoma cruzi 5'-AMP-activated protein kinase catalytic subunit alpha, putative 0.0451 0.0222 0.1251
Plasmodium falciparum protein serine/threonine kinase-1 0.0666 0.0548 0.3276
Echinococcus multilocularis receptor type tyrosine protein phosphatase F 0.0396 0.0139 0.0151
Loa Loa (eye worm) TK/FER protein kinase 0.1298 0.1507 0.1507
Echinococcus multilocularis mitogen activated protein kinase 11 0.0955 0.0987 0.129
Echinococcus granulosus homeodomain interacting protein kinase 3 0.0866 0.0852 0.091
Leishmania major protein kinase, putative,SNF1-related protein kinases, putative 0.0451 0.0222 0.068
Entamoeba histolytica protein kinase, putative 0.0412 0.0163 0.0632
Giardia lamblia Kinase, CMGC GSK 0.0766 0.07 0.3598
Leishmania major mitogen activated protein kinase, putative,map kinase, putative 0.0487 0.0277 0.1018
Echinococcus granulosus calcium:calmodulin dependent protein kinase type 0.0498 0.0293 0.0294
Echinococcus granulosus serine:threonine protein kinase mig 15 0.092 0.0934 0.1
Leishmania major mitogen activated protein kinase 4, putative;with=GeneDB:LmxM19.1440 0.0487 0.0277 0.1018
Echinococcus granulosus proto oncogene tyrosine protein kinase LCK 0.1179 0.1328 0.1434
Echinococcus multilocularis fibroblast growth factor receptor 4 0.1505 0.1822 0.2412
Echinococcus multilocularis tyrosine protein kinase HCK 0.073 0.0645 0.0831
Loa Loa (eye worm) TK/ALK protein kinase 0.1719 0.2146 0.2146
Brugia malayi STE20-like kinase MST 0.156 0.1906 0.1903
Trypanosoma cruzi casein kinase II, putative 0.0589 0.0432 0.2451
Loa Loa (eye worm) TK/FAK protein kinase 0.2368 0.3132 0.3132
Echinococcus multilocularis tyrosine protein kinase Srms 0.0989 0.1039 0.136
Entamoeba histolytica protein kinase, putative 0.0367 0.0095 0.0317
Trichomonas vaginalis STE family protein kinase 0.0493 0.0286 0.1297
Echinococcus multilocularis expressed protein 0.0377 0.0111 0.0113
Onchocerca volvulus Serine\/threonine protein kinase homolog 0.1655 0.2049 0.2253
Giardia lamblia Kinase, NEK 0.0812 0.0771 0.4027
Echinococcus multilocularis mitogen activated protein kinase 3 0.0487 0.0277 0.0337
Onchocerca volvulus Tyrosine kinase homolog 0.6211 0.8963 1
Schistosoma mansoni serine/threonine protein kinase 0.0487 0.0277 0.0519
Trypanosoma cruzi STE/STE20 serine/threonine-protein kinase, putative 0.0493 0.0286 0.1618
Echinococcus multilocularis dual specificity 0.05 0.0297 0.0363
Leishmania major rac serine-threonine kinase, putative,protein kinase, putative 0.0739 0.0659 0.3347
Trichomonas vaginalis CAMK family protein kinase 0.0508 0.0309 0.1402
Brugia malayi Protein kinase domain containing protein 0.0473 0.0256 0.0253
Echinococcus multilocularis hemicentin 1 0.0341 0.0055 0.0038
Entamoeba histolytica serine/threonine protein kinase, putative 0.1457 0.1749 0.7996
Entamoeba histolytica serine/threonine- protein kinase 6 , putative 0.1275 0.1472 0.6711
Echinococcus multilocularis C2 calcium dependent membrane targeting 0.033 0.0038 0.0016
Echinococcus multilocularis serine:threonine protein kinase PAK 4 0.1213 0.1378 0.1815
Loa Loa (eye worm) hypothetical protein 0.0568 0.04 0.04
Trichomonas vaginalis CAMK family protein kinase 0.0451 0.0222 0.1003
Giardia lamblia Kinase, STE STE20 0.0493 0.0286 0.1071
Schistosoma mansoni hypothetical protein 0.0546 0.0366 0.0687
Trypanosoma cruzi CMGC/DYRK protein kinase, putative 0.0726 0.064 0.3644
Brugia malayi casein kinase I 0.0562 0.0391 0.0387
Plasmodium vivax tyrosine kinase-like protein, putative 0.0369 0.0098 0.0224
Trichomonas vaginalis CMGC family protein kinase 0.0589 0.0432 0.1965
Echinococcus multilocularis casein kinase ii subunit alpha 0.0589 0.0432 0.0544
Onchocerca volvulus 0.0536 0.0351 0.035
Echinococcus multilocularis tyrosine protein kinase Fps85D 0.1298 0.1507 0.1989
Echinococcus multilocularis contactin neuroglian septate junction protein 0.0396 0.0139 0.0151
Leishmania major protein kinase A catalytic subunit 0.0545 0.0365 0.1551
Brugia malayi cell division control protein 2 homolog 0.0705 0.0607 0.0604
Entamoeba histolytica cell division protein kinase 2, putative 0.0705 0.0607 0.2696
Onchocerca volvulus Serine\/threonine kinase homolog 0.1457 0.1749 0.1917
Brugia malayi Kinase associated domain 1 family protein 0.0546 0.0366 0.0362
Echinococcus multilocularis Protein kinase C, brain isozyme 0.1534 0.1865 0.247
Echinococcus granulosus cyclin dependent kinase 0.0705 0.0607 0.064
Schistosoma mansoni ephrin receptor 0.0673 0.0559 0.1054
Schistosoma mansoni tyrosine kinase 0.2212 0.2895 0.5488
Loa Loa (eye worm) AGC/RSK/P70 protein kinase 0.1697 0.2113 0.2113
Leishmania major mitogen-activated protein kinase 3, putative,map kinase 3, putative 0.0955 0.0987 0.5347
Leishmania major cell division protein kinase 2,cdc2-related kinase 0.0705 0.0607 0.3032
Plasmodium falciparum calcium-dependent protein kinase 5 0.0498 0.0293 0.1423
Plasmodium falciparum calcium-dependent protein kinase 4 0.0498 0.0293 0.1423
Echinococcus granulosus serine:threonine protein kinase 12 B 0.1275 0.1472 0.1594
Trypanosoma brucei CMGC/DYRK protein kinase, putative 0.0726 0.064 0.2556
Echinococcus multilocularis dual specificity 0.05 0.0297 0.0363
Plasmodium falciparum protein kinase 5 0.0705 0.0607 0.3708
Echinococcus granulosus sodium:potassium dependent atpase beta subunit 0.0739 0.0659 0.0697
Trichomonas vaginalis CAMK family protein kinase 0.0451 0.0222 0.1003
Schistosoma mansoni tyrosine kinase 0.0933 0.0953 0.1802
Entamoeba histolytica protein kinase, putative 0.05 0.0297 0.1253
Loa Loa (eye worm) CMGC/DYRK/HIPK protein kinase 0.0866 0.0852 0.0852
Onchocerca volvulus 0.1664 0.2063 0.2269
Brugia malayi Doublecortin family protein 0.0654 0.0531 0.0527
Loa Loa (eye worm) CMGC/MAPK/P38 protein kinase 0.0955 0.0987 0.0987
Giardia lamblia Kinase, CMGC CK2 0.0589 0.0432 0.1958
Brugia malayi Casein kinase II, alpha chain 0.0589 0.0432 0.0428
Echinococcus granulosus NDR protein kinase 0.0958 0.0992 0.1064
Giardia lamblia Kinase, CAMK CAMKL 0.0451 0.0222 0.068
Schistosoma mansoni serine/threonine protein kinase 0.0545 0.0365 0.0685
Echinococcus granulosus cyclin dependent kinase 5 0.0705 0.0607 0.064
Leishmania major cell division related protein kinase 2,cdc2-related kinase 0.0705 0.0607 0.3032
Echinococcus multilocularis mitogen activated protein kinase kinase kinase 0.1286 0.1489 0.1964
Echinococcus granulosus tyrosine protein kinase shark 0.1192 0.1347 0.1456
Echinococcus granulosus serine threonine protein kinase nrc 0.0911 0.0921 0.0986
Brugia malayi cAMP-dependent protein kinase catalytic subunit, putative 0.0545 0.0365 0.0361
Trichomonas vaginalis CAMK family protein kinase 0.0451 0.0222 0.1003
Echinococcus multilocularis 3 phosphoinositide dependent protein kinase 1 0.0473 0.0256 0.0309
Schistosoma mansoni mitogen-activated protein kinase kinase kinase 3 mapkkk3 mekk3 0.0429 0.0189 0.0351
Loa Loa (eye worm) CMGC/DYRK/DYRK2 protein kinase 0.05 0.0297 0.0297
Onchocerca volvulus Serine\/threonine kinase homolog 0.0708 0.0613 0.0644
Echinococcus granulosus ephrin type A receptor 4 A 0.0673 0.0559 0.0587
Toxoplasma gondii protein kinase G AGC kinase family member PKG 0.0588 0.043 0.1934
Schistosoma mansoni protein kinase 0.0664 0.0545 0.1027
Trichomonas vaginalis CMGC family protein kinase 0.0589 0.0432 0.1965
Echinococcus granulosus casein kinase i 0.0562 0.0391 0.0401
Plasmodium falciparum serine/threonine protein kinase, putative 0.1275 0.1472 1
Onchocerca volvulus 0.0395 0.0137 0.011
Brugia malayi Protein kinase domain containing protein 0.2771 0.3743 0.3741
Trypanosoma cruzi kinetoplastid kinetochore protein 19, putative 0.0666 0.0548 0.3118
Loa Loa (eye worm) CAMK/PKD protein kinase 0.119 0.1344 0.1344
Echinococcus granulosus serine:threonine protein kinase TAO1 0.0946 0.0973 0.1044
Echinococcus granulosus serine:threonine protein kinase PAK 4 0.1213 0.1378 0.149
Brugia malayi Furin-like cysteine rich region family protein 0.3779 0.5272 0.5271
Echinococcus granulosus glycogen synthase kinase 3 beta 0.0766 0.07 0.0743
Trichomonas vaginalis CK1 family protein kinase 0.0562 0.0391 0.1777
Brugia malayi Immunoglobulin I-set domain containing protein 0.0396 0.0139 0.0136
Echinococcus multilocularis cGMP dependent protein kinase 1 0.0588 0.043 0.0542
Echinococcus granulosus tyrosine protein kinase Lyn 0.1352 0.1589 0.1723
Echinococcus granulosus mitogen activated protein kinase 11 0.0955 0.0987 0.1059
Trichomonas vaginalis CAMK family protein kinase 0.0451 0.0222 0.1003
Onchocerca volvulus 0.0562 0.0391 0.0395
Echinococcus multilocularis myosin iiia 0.0493 0.0286 0.0349
Echinococcus multilocularis cGMP dependent protein kinase 1 0.0588 0.043 0.0542
Entamoeba histolytica protein kinase, putative 0.1742 0.2181 1
Echinococcus granulosus twitchin 0.1015 0.1078 0.1159
Trichomonas vaginalis serine/threonine-protein kinase sgk, putative 0.0891 0.089 0.4072
Loa Loa (eye worm) CMGC/CLK protein kinase 0.0666 0.0548 0.0548
Giardia lamblia Kinase, CMGC GSK 0.0766 0.07 0.3598
Schistosoma mansoni protein kinase 0.0562 0.0391 0.0734
Loa Loa (eye worm) CAMK/TSSK protein kinase 0.2489 0.3316 0.3316
Trichomonas vaginalis CAMK family protein kinase 0.066 0.0539 0.2458
Echinococcus granulosus tyrosine protein kinase HCK 0.073 0.0645 0.0682
Trypanosoma cruzi casein kinase, putative 0.0562 0.0391 0.2216
Trichomonas vaginalis AGC family protein kinase 0.0323 0.0028 0.0109
Loa Loa (eye worm) TK/FER protein kinase 0.0536 0.0351 0.0351
Onchocerca volvulus 0.1837 0.2325 0.2562
Trichomonas vaginalis CMGC family protein kinase 0.0705 0.0607 0.2773
Trichomonas vaginalis CAMK family protein kinase 0.0451 0.0222 0.1003
Echinococcus multilocularis tyrosine protein kinase 0.1013 0.1076 0.1409
Brugia malayi Protein kinase domain containing protein 0.0676 0.0563 0.056
Echinococcus granulosus lachesin 0.0341 0.0055 0.0031
Loa Loa (eye worm) hypothetical protein 0.086 0.0844 0.0844
Leishmania major protein kinase, putative 0.1275 0.1472 0.831
Loa Loa (eye worm) hypothetical protein 0.085 0.0828 0.0828
Schistosoma mansoni growth factor receptor-bound protein 0.0456 0.023 0.0429
Entamoeba histolytica protein kinase, putative 0.0377 0.0111 0.0391
Brugia malayi C1-like domain containing protein 0.119 0.1344 0.1341
Trichomonas vaginalis AGC family protein kinase 0.0323 0.0028 0.0109
Echinococcus granulosus protein kinase c epsilon type 0.1288 0.1492 0.1616
Trypanosoma brucei Vacuolar sorting protein 39 domain 1/Vacuolar sorting protein 39 domain 2, putative 0.0429 0.0189 0.0377
Loa Loa (eye worm) CMGC/DYRK/DYRK1 protein kinase 0.0726 0.064 0.064
Trypanosoma cruzi kinetoplastid kinetochore protein 10, putative 0.0666 0.0548 0.3118
Trypanosoma cruzi Vacuolar sorting protein 39 domain 1/Vacuolar sorting protein 39 domain 2, putative 0.0429 0.0189 0.106
Echinococcus multilocularis tyrosine protein kinase lyn lyn a protein tyrosine kinase lymphocyte specific protein tyrosine kinase 0.1179 0.1328 0.1748
Brugia malayi Phorbol esters/diacylglycerol binding domain 0.119 0.1344 0.1341
Trichomonas vaginalis CAMK family protein kinase 0.0451 0.0222 0.1003
Trypanosoma brucei cdc2-related kinase 3 0.0705 0.0607 0.24
Trypanosoma cruzi mitogen-activated protein kinase 11, putative 0.0487 0.0277 0.1568
Brugia malayi map kinase activated protein kinase protein 2 0.2412 0.3198 0.3196
Echinococcus granulosus serine:threonine protein kinase PAK 3 0.0501 0.0299 0.03
Echinococcus granulosus serine:threonine protein kinase 0.0676 0.0563 0.0592
Plasmodium vivax serine/threonine kinase-1, putative 0.0666 0.0548 0.3427
Echinococcus multilocularis serine:threonine protein kinase PLK1 0.1457 0.1749 0.2314
Loa Loa (eye worm) STE/STE20/MST protein kinase 0.156 0.1906 0.1906
Entamoeba histolytica protein kinase, putative 0.0407 0.0156 0.0602
Trypanosoma cruzi cdc2-related kinase 1 0.0705 0.0607 0.3458
Loa Loa (eye worm) hypothetical protein 0.1016 0.108 0.108
Plasmodium falciparum glycogen synthase kinase 3 0.0766 0.07 0.4384
Echinococcus granulosus tyrosine protein kinase Src64B 0.1179 0.1328 0.1434
Echinococcus multilocularis tyrosine protein kinase lyn tyrosine protein kinase blk 0.1179 0.1328 0.1748
Trypanosoma cruzi polo-like protein kinase, putative 0.1457 0.1749 1
Loa Loa (eye worm) hypothetical protein 0.0532 0.0346 0.0346
Loa Loa (eye worm) TK/KIN16 protein kinase 0.6894 1 1
Brugia malayi Temporarily assigned gene name protein 59 0.0429 0.0189 0.0185
Echinococcus multilocularis serine:threonine protein kinase MARK2 0.1221 0.1391 0.1833
Loa Loa (eye worm) sex muscle abnormal protein 5 0.045 0.022 0.022
Echinococcus multilocularis mitogen activated protein kinase 14 0.0955 0.0987 0.129
Trichomonas vaginalis CMGC family protein kinase 0.0589 0.0432 0.1965
Trichomonas vaginalis CK1 family protein kinase 0.0562 0.0391 0.1777
Echinococcus granulosus cAMP dependent protein kinase catalytic subunit 0.0545 0.0365 0.0373
Giardia lamblia Kinase, CAMK CAMKL 0.0451 0.0222 0.068
Loa Loa (eye worm) hypothetical protein 0.0451 0.0222 0.0222
Loa Loa (eye worm) variant SH3 domain-containing protein 0.0322 0.0027 0.0027
Loa Loa (eye worm) hypothetical protein 0.2489 0.3316 0.3316
Trypanosoma brucei STE20-like serine/threonine-protein kinase 1, putative 0.0493 0.0286 0.0848
Loa Loa (eye worm) hypothetical protein 0.0429 0.0189 0.0189
Echinococcus multilocularis tyrosine protein kinase Abl 0.1217 0.1385 0.1825
Loa Loa (eye worm) hypothetical protein 0.0429 0.0189 0.0189
Giardia lamblia Kinase, PLK 0.1457 0.1749 1
Loa Loa (eye worm) CK1/CK1/CK1-A protein kinase 0.0562 0.0391 0.0391
Trichomonas vaginalis AGC family protein kinase 0.0545 0.0365 0.1658
Schistosoma mansoni serine/threonine protein kinase 0.0588 0.043 0.0809
Echinococcus multilocularis cyclin dependent kinase 1 0.0705 0.0607 0.078
Brugia malayi probable protein kinase 0.1092 0.1196 0.1192
Plasmodium falciparum serine/threonine protein kinase KIN 0.0451 0.0222 0.0905
Brugia malayi Protein kinase domain containing protein 0.0536 0.0351 0.0347
Brugia malayi Immunoglobulin I-set domain containing protein 0.0341 0.0055 0.0051
Echinococcus multilocularis rho associated protein kinase 0.1837 0.2325 0.3087
Trichomonas vaginalis AGC family protein kinase 0.0323 0.0028 0.0109
Echinococcus granulosus protein tyrosine kinase 0.2344 0.3095 0.3383
Toxoplasma gondii protein kinase, cAMP-dependent, catalytic chain 0.0545 0.0365 0.1621
Brugia malayi Protein kinase domain containing protein 0.1655 0.2049 0.2046
Echinococcus multilocularis protein kinase c iota type 0.1794 0.226 0.3001
Leishmania major protein kinase, putative 0.0448 0.0218 0.0657
Schistosoma mansoni vav2 0.0626 0.0489 0.092
Brugia malayi Tyrosine-protein kinase abl-1 0.0794 0.0743 0.074
Loa Loa (eye worm) calcium/calmodulin-dependent protein kinase ID 0.0498 0.0293 0.0293
Trichomonas vaginalis CAMK family protein kinase 0.1054 0.1137 0.5205
Onchocerca volvulus 0.0397 0.014 0.0114
Trichomonas vaginalis CMGC family protein kinase 0.05 0.0297 0.1345
Brugia malayi Protein kinase domain containing protein 0.0666 0.0548 0.0544
Trichomonas vaginalis AGC family protein kinase 0.1064 0.1152 0.5274
Echinococcus multilocularis serine threonine protein kinase nrc serine threonine protein kinase gad 0.0911 0.0921 0.1201
Echinococcus granulosus tyrosine kinase 0.0989 0.1039 0.1117
Loa Loa (eye worm) TK/ABL protein kinase 0.1821 0.2302 0.2302
Plasmodium vivax rac-beta serine/threonine protein kinase, putative 0.0911 0.0921 0.6077
Echinococcus multilocularis cAMP dependent protein kinase catalytic subunit 0.0545 0.0365 0.0454
Echinococcus granulosus roundabout 2 0.1072 0.1165 0.1255
Echinococcus granulosus neuroglian 0.0396 0.0139 0.0124
Echinococcus multilocularis cAMP dependent protein kinase catalytic subunit 0.0545 0.0365 0.0454
Schistosoma mansoni serine/threonine protein kinase 0.148 0.1783 0.3377
Echinococcus multilocularis basic fibroblast growth factor receptor 1 A 0.1505 0.1822 0.2412
Loa Loa (eye worm) CMGC/GSK protein kinase 0.0766 0.07 0.07
Echinococcus granulosus serine:threonine protein kinase MARK2 0.1221 0.1391 0.1505
Echinococcus granulosus raf serine:threonine protein kinase 0.2971 0.4046 0.4431
Echinococcus granulosus melanoma receptor tyrosine protein kinase 0.2488 0.3314 0.3625
Trypanosoma brucei cdc2-related kinase 1 0.0705 0.0607 0.24
Echinococcus multilocularis receptor type tyrosine protein phosphatase 0.0396 0.0139 0.0151
Trichomonas vaginalis CMGC family protein kinase 0.0487 0.0277 0.1257
Brugia malayi Stress-activated protein kinase jnk-1 0.1607 0.1976 0.1973
Echinococcus granulosus tyrosine protein kinase Fps85D 0.1298 0.1507 0.1633
Brugia malayi Immunoglobulin I-set domain containing protein 0.1671 0.2074 0.2071
Brugia malayi Protein kinase domain containing protein 0.1213 0.1378 0.1375
Brugia malayi Immunoglobulin I-set domain containing protein 0.0396 0.0139 0.0136
Trypanosoma cruzi glycogen synthase kinase 3, putative 0.0766 0.07 0.399
Echinococcus granulosus proto oncogene serine:threonine protein kinase 0.1655 0.2049 0.223
Echinococcus multilocularis mitogen activated protein kinase 14 0.0955 0.0987 0.129
Echinococcus granulosus CDC7 cell division cycle 7 0.0405 0.0152 0.0138
Echinococcus granulosus defective proboscis extension response 0.0676 0.0564 0.0592
Schistosoma mansoni receptor tyrosine phosphatase type r2a 0.0396 0.0139 0.0257
Echinococcus granulosus Immunoglobulin 0.0676 0.0564 0.0592
Echinococcus multilocularis tyrosine protein kinase Fyn 0.1179 0.1328 0.1748
Trichomonas vaginalis CMGC family protein kinase 0.0705 0.0607 0.2773
Trichomonas vaginalis CMGC family protein kinase 0.0487 0.0277 0.1257
Echinococcus multilocularis enhancer of mRNA decapping protein 4 0.0372 0.0103 0.0103
Trichomonas vaginalis AGC family protein kinase 0.1275 0.1472 0.6745
Loa Loa (eye worm) CAMK/CAMKL/MARK protein kinase 0.0676 0.0563 0.0563
Schistosoma mansoni titin 0.0341 0.0055 0.0097
Echinococcus granulosus Vam6:Vps39 protein 0.0429 0.0189 0.0179
Trichomonas vaginalis AGC family protein kinase 0.1275 0.1472 0.6745
Echinococcus granulosus neuroglian 0.0842 0.0816 0.0871
Schistosoma mansoni serine/threonine protein kinase 0.1607 0.1976 0.3743
Trichomonas vaginalis CMGC family protein kinase 0.0766 0.07 0.3199
Echinococcus multilocularis protein kinase shaggy 0.0766 0.07 0.0905
Echinococcus granulosus protein kinase c iota type 0.1794 0.226 0.2463
Trichomonas vaginalis AGC family protein kinase 0.1275 0.1472 0.6745
Leishmania major protein kinase, putative,polo-like protein kinase, putative 0.1457 0.1749 1
Schistosoma mansoni tyrosine kinase 0.2344 0.3095 0.5867
Entamoeba histolytica PH domain containing protein kinase, putative 0.0956 0.0989 0.4466
Schistosoma mansoni serine/threonine protein kinase 0.2971 0.4046 0.7672
Schistosoma mansoni diacylglycerol kinase theta 0.0322 0.0027 0.0043
Toxoplasma gondii cell-cycle-associated protein kinase DYRK2, putative 0.05 0.0297 0.1294
Trichomonas vaginalis AGC family protein kinase 0.1742 0.2181 1
Loa Loa (eye worm) STE/STE20/SLK protein kinase 0.0826 0.0791 0.0791
Echinococcus granulosus unc 13 munc13 0.033 0.0038 0.0013
Loa Loa (eye worm) hypothetical protein 0.0396 0.0139 0.0139
Loa Loa (eye worm) hypothetical protein 0.0341 0.0055 0.0055
Brugia malayi serine/threonine protein kinase 6 0.1275 0.1472 0.1469
Brugia malayi diacylglycerol kinase 0.0322 0.0027 0.0023
Brugia malayi Immunoglobulin I-set domain containing protein 0.0396 0.0139 0.0136
Onchocerca volvulus 0.0405 0.0152 0.0127
Echinococcus multilocularis serine:threonine protein kinase PAK 3 0.0501 0.0299 0.0366
Loa Loa (eye worm) hypothetical protein 0.0342 0.0057 0.0057
Schistosoma mansoni serine/threonine protein kinase 0.1534 0.1865 0.3533
Echinococcus granulosus calcium:calmodulin dependent protein kinase type 0.0498 0.0293 0.0294
Echinococcus granulosus growth factor receptor bound protein 2 0.0456 0.023 0.0224
Trichomonas vaginalis AGC family protein kinase 0.1742 0.2181 1
Entamoeba histolytica protein kinase domain containing protein 0.0766 0.07 0.3127
Schistosoma mansoni protein kinase 0.1259 0.1448 0.2742
Entamoeba histolytica protein kinase domain containing protein 0.0448 0.0218 0.089
Trichomonas vaginalis CAMK family protein kinase 0.0508 0.0309 0.1402
Schistosoma mansoni serine/threonine protein kinase 0.0666 0.0548 0.1033
Trypanosoma cruzi Vacuolar sorting protein 39 domain 1/Vacuolar sorting protein 39 domain 2, putative 0.0429 0.0189 0.106
Plasmodium falciparum calcium-dependent protein kinase 2 0.0498 0.0293 0.1423
Brugia malayi RhoGAP domain containing protein 0.0322 0.0027 0.0023
Echinococcus multilocularis neuroglian 0.0842 0.0816 0.1061
Trichomonas vaginalis CMGC family protein kinase 0.0589 0.0432 0.1965
Loa Loa (eye worm) hypothetical protein 0.0546 0.0366 0.0366
Echinococcus multilocularis tyrosine kinase 0.0536 0.0351 0.0435
Leishmania major glycogen synthase kinase, putative;with=GeneDB:LinJ18_V3.0270 0.0766 0.07 0.3598
Trichomonas vaginalis STE family protein kinase 0.0812 0.0771 0.3522
Loa Loa (eye worm) TK protein kinase 0.0989 0.1039 0.1039
Brugia malayi ephrin receptor 1 precursor 0.0463 0.024 0.0237
Trypanosoma cruzi cAMP-dependent protein kinase catalytic subunit 1 0.0545 0.0365 0.2068
Trichomonas vaginalis AGC family protein kinase 0.0323 0.0028 0.0109
Loa Loa (eye worm) hypothetical protein 0.0536 0.0351 0.0351
Toxoplasma gondii cell-cycle-associated protein kinase GSK, putative 0.0766 0.07 0.3229
Onchocerca volvulus 0.086 0.0844 0.0902
Echinococcus multilocularis ribosomal protein s6 kinase beta 1 0.0958 0.0992 0.1297
Trypanosoma brucei polo-like protein kinase 0.1457 0.1749 0.7915
Echinococcus multilocularis tyrosine protein kinase Fyn 0.1179 0.1328 0.1748
Brugia malayi Protein kinase domain containing protein 0.0377 0.0111 0.0107
Echinococcus multilocularis serine:threonine protein kinase 38 0.0958 0.0992 0.1297
Trichomonas vaginalis AGC family protein kinase 0.0473 0.0256 0.1159
Schistosoma mansoni serine/threonine protein kinase 0.0405 0.0152 0.0281
Leishmania major serine/threonine-protein kinase, putative,protein kinase, putative 0.0726 0.064 0.3229
Loa Loa (eye worm) raf kinase 0.2695 0.3627 0.3627
Echinococcus multilocularis raf serine:threonine protein kinase 0.2971 0.4046 0.5399
Trypanosoma brucei calcium/calmodulin-dependent protein kinase, putative 0.0498 0.0293 0.0882
Schistosoma mansoni tyrosine kinase 0.1505 0.1822 0.3451
Echinococcus multilocularis serine:threonine protein kinase MRCK beta 0.1224 0.1395 0.1838
Echinococcus multilocularis Immunoglobulin 0.0676 0.0564 0.0721
Brugia malayi Calcium/calmodulin-dependent protein kinase type II alpha chain 0.1361 0.1603 0.16
Plasmodium vivax calcium-dependent protein kinase 1, putative 0.0498 0.0293 0.1615
Echinococcus granulosus phosphorylase kinase gamma subunit 0.0708 0.0613 0.0646
Loa Loa (eye worm) AGC/RSK/MSK protein kinase 0.1064 0.1152 0.1152
Schistosoma mansoni serine/threonine protein kinase 0.2412 0.3198 0.6063
Echinococcus multilocularis 0.0664 0.0545 0.0696
Echinococcus multilocularis proto oncogene tyrosine protein kinase LCK 0.1179 0.1328 0.1748
Loa Loa (eye worm) hypothetical protein 0.0732 0.0648 0.0648
Toxoplasma gondii calcium-dependent protein kinase CDPK2A 0.0498 0.0293 0.1278
Giardia lamblia Kinase, CMGC CDK 0.0705 0.0607 0.3032
Entamoeba histolytica protein kinase, putative 0.0726 0.064 0.2846
Trichomonas vaginalis AGC family protein kinase 0.0473 0.0256 0.1159
Toxoplasma gondii calcium-dependent protein kinase CDPK2B 0.0498 0.0293 0.1278
Echinococcus multilocularis roundabout 2 0.0396 0.0139 0.0151
Loa Loa (eye worm) calcium/calmodulin-dependent protein kinase subunit type II alpha 0.1361 0.1603 0.1603
Schistosoma mansoni mitogen-activated protein kinase kinase kinase 3 mapkkk3 mekk3 0.0429 0.0189 0.0351
Giardia lamblia Kinase, CMGC MAPK 0.0487 0.0277 0.1018
Loa Loa (eye worm) hypothetical protein 0.045 0.022 0.022
Loa Loa (eye worm) hypothetical protein 0.1182 0.1332 0.1332
Schistosoma mansoni glycogen synthase kinase 3-related (gsk3) (cmgc group III) 0.0766 0.07 0.1322
Loa Loa (eye worm) CMGC/SRPK protein kinase 0.0377 0.0111 0.0111
Schistosoma mansoni serine/threonine protein kinase 0.0718 0.0628 0.1184
Toxoplasma gondii Tyrosine kinase-like (TKL) protein 0.0369 0.0098 0.0341
Brugia malayi Protein kinase domain containing protein 0.2489 0.3316 0.3313
Loa Loa (eye worm) TK/FER protein kinase 0.0536 0.0351 0.0351
Schistosoma mansoni serine/threonine protein kinase 0.0498 0.0293 0.0549
Schistosoma mansoni proto-oncogene tyrosine-protein kinase src 0.0726 0.0639 0.1206
Toxoplasma gondii CMGC kinase, MAPK family (ERK) MAPK-1 0.0487 0.0277 0.1203
Plasmodium vivax glycogen synthase kinase 3, putative 0.0766 0.07 0.4509
Toxoplasma gondii casein kinase I 0.0562 0.0391 0.1745
Brugia malayi p70 ribosomal S6 kinase beta 0.1697 0.2113 0.211
Schistosoma mansoni protein kinase C 0.033 0.0038 0.0066
Schistosoma mansoni serine/threonine protein kinase 0.0451 0.0222 0.0414
Echinococcus multilocularis serine:threonine protein kinase N2 0.053 0.0342 0.0424
Loa Loa (eye worm) hypothetical protein 0.1819 0.2298 0.2298
Loa Loa (eye worm) hypothetical protein 0.0498 0.0293 0.0293
Schistosoma mansoni tyrosine kinase 0.2488 0.3314 0.6283
Loa Loa (eye worm) SRC-1 0.1179 0.1328 0.1328
Trypanosoma cruzi cdc2-related kinase 1 0.0705 0.0607 0.3458
Trypanosoma brucei casein kinase I, isoform 2 0.0562 0.0391 0.1352
Echinococcus multilocularis tyrosine protein kinase Src42A 0.072 0.063 0.0811
Mycobacterium ulcerans hypothetical protein 0.0415 0.0168 0.5
Schistosoma mansoni chimerin-related rho-gtpase-activating protein 0.0582 0.0421 0.0791
Schistosoma mansoni protein kinase 0.0501 0.0299 0.056
Echinococcus granulosus tyrosine protein kinase Btk29A 0.1963 0.2517 0.2745
Trichomonas vaginalis CMGC family protein kinase 0.0487 0.0277 0.1257
Schistosoma mansoni serine/threonine protein kinase 0.0562 0.0391 0.0734
Schistosoma mansoni protein kinase 0.1859 0.2358 0.4469
Loa Loa (eye worm) STE/STE20/MSN protein kinase 0.0664 0.0545 0.0545
Trypanosoma brucei kinetoplastid kinetochore protein 10 0.0666 0.0548 0.2113
Echinococcus multilocularis ribosomal protein S6 kinase alpha 3 0.148 0.1783 0.236
Echinococcus granulosus C2 calcium dependent membrane targeting 0.033 0.0038 0.0013
Loa Loa (eye worm) AGC/PKC/IOTA protein kinase 0.1046 0.1125 0.1125
Echinococcus granulosus myotubularin protein 13 0.0367 0.0094 0.0075
Echinococcus multilocularis calcium:calmodulin dependent protein kinase I 0.0407 0.0156 0.0174
Trichomonas vaginalis CMGC family protein kinase 0.05 0.0297 0.1345
Echinococcus granulosus cGMP dependent protein kinase 0.0588 0.043 0.0445
Echinococcus granulosus roundabout 2 0.0396 0.0139 0.0124
Trichomonas vaginalis AGC family protein kinase 0.0323 0.0028 0.0109
Brugia malayi casein kinase 1, delta 0.0562 0.0391 0.0387
Trypanosoma brucei aurora B kinase 0.1275 0.1472 0.6577
Schistosoma mansoni tyrosine kinase 0.1192 0.1347 0.255
Loa Loa (eye worm) TK/INSR protein kinase 0.2771 0.3743 0.3743
Schistosoma mansoni defective proboscis extension response (dpr)-related 0.0676 0.0564 0.1063
Echinococcus granulosus tyrosine protein kinase Fyn 0.1179 0.1328 0.1434
Echinococcus granulosus titin 0.0395 0.0137 0.0122
Echinococcus multilocularis proto oncogene serine:threonine protein kinase 0.1655 0.2049 0.2717
Entamoeba histolytica protein kinase, putative 0.0377 0.0111 0.0391
Brugia malayi Protein kinase domain containing protein 0.0726 0.064 0.0636
Brugia malayi Peroxidasin 0.0342 0.0057 0.0053
Trypanosoma cruzi CMGC/DYRK protein kinase, putative 0.0726 0.064 0.3644
Schistosoma mansoni rap gtpase-activating protein 0.0429 0.0189 0.0351
Loa Loa (eye worm) STE/STE20/TAO protein kinase 0.0946 0.0973 0.0973
Echinococcus granulosus mitogen activated protein kinase kinase kinase 0.0601 0.045 0.0467
Trichomonas vaginalis CAMK family protein kinase 0.066 0.0539 0.2458
Brugia malayi Calcium/calmodulin-dependent protein kinase type II alpha chain 0.0498 0.0293 0.029
Trichomonas vaginalis AGC family protein kinase 0.1742 0.2181 1
Schistosoma mansoni serine/threonine protein kinase 0.1288 0.1492 0.2825
Onchocerca volvulus 0.0389 0.0129 0.0101
Entamoeba histolytica casein kinase 1, putative 0.0562 0.0391 0.169
Echinococcus granulosus protein kinase 0.0664 0.0545 0.0572
Brugia malayi Protein kinase domain containing protein 0.0958 0.0992 0.0989
Echinococcus multilocularis casein kinase I alpha 0.0562 0.0391 0.0489
Entamoeba histolytica protein kinase , putative 0.1275 0.1472 0.6711
Echinococcus granulosus Glutaredoxin protein 5 0.0739 0.0659 0.0697
Entamoeba histolytica protein kinase, putative 0.0412 0.0163 0.0632
Echinococcus granulosus dual specificity testis-specific protein kinase 0.1259 0.1448 0.1568
Loa Loa (eye worm) AGC/RSK/RSK protein kinase 0.148 0.1783 0.1783
Echinococcus multilocularis cyclin dependent kinase 1 0.0705 0.0607 0.078
Schistosoma mansoni serine/threonine protein kinase 0.0545 0.0365 0.0685
Schistosoma mansoni chimerin-related rho-gtpase-activating protein 0.0582 0.0421 0.0791
Schistosoma mansoni serine/threonine protein kinase 0.05 0.0297 0.0556
Entamoeba histolytica PH domain containing protein kinase, putative 0.0956 0.0989 0.4466
Echinococcus granulosus casein kinase I alpha 0.0562 0.0391 0.0401
Echinococcus multilocularis tyrosine protein kinase ABL1 0.1821 0.2302 0.3057
Brugia malayi SRC-1 0.1179 0.1328 0.1324
Echinococcus granulosus tyrosine protein kinase Blk 0.0989 0.1039 0.1117
Entamoeba histolytica casein kinase, putative 0.0562 0.0391 0.169
Schistosoma mansoni ephrin receptor 0.0332 0.0041 0.0071
Trichomonas vaginalis AGC family protein kinase 0.1742 0.2181 1
Brugia malayi Dual-specificity tyrosine-phosphorylation regulated kinase 2 0.05 0.0297 0.0293
Loa Loa (eye worm) hypothetical protein 0.0322 0.0027 0.0027
Echinococcus granulosus serine:threonine protein kinase 0.0676 0.0563 0.0592
Schistosoma mansoni protein kinase 0.1286 0.1489 0.2819
Echinococcus granulosus calcium:calmodulin dependent protein kinase type 0.1859 0.2358 0.2571
Loa Loa (eye worm) TK protein kinase 0.1671 0.2074 0.2074
Schistosoma mansoni tyrosine kinase 0.2212 0.2895 0.5488
Loa Loa (eye worm) hypothetical protein 0.033 0.0038 0.0038
Trichomonas vaginalis AGC family protein kinase 0.1742 0.2181 1
Echinococcus multilocularis dual specificity testis specific protein kinase 0.1259 0.1448 0.191
Loa Loa (eye worm) hypothetical protein 0.1016 0.108 0.108
Echinococcus multilocularis neuroglian 0.0396 0.0139 0.0151
Echinococcus multilocularis epidermal growth factor receptor 0.2488 0.3314 0.4416
Entamoeba histolytica protein kinase domain containing protein 0.0766 0.07 0.3127
Schistosoma mansoni tyrosine kinase 0.3779 0.5272 1
Brugia malayi hypothetical protein 0.0732 0.0648 0.0645
Schistosoma mansoni Neurotrimin precursor (hNT) 0.0676 0.0564 0.1063
Schistosoma mansoni serine/threonine protein kinase 0.1837 0.2325 0.4406
Onchocerca volvulus 0.0696 0.0594 0.0622
Echinococcus multilocularis serine:threonine kinase SAD 1 0.0451 0.0222 0.0263
Brugia malayi Protein kinase domain containing protein 0.1232 0.1407 0.1404
Echinococcus granulosus tyrosine protein kinase transmembrane receptor 0.0442 0.0209 0.0201
Entamoeba histolytica serine/threonine protein kinase, putative 0.0451 0.0222 0.0908
Loa Loa (eye worm) STE/STE20/PAKB protein kinase 0.1407 0.1673 0.1673
Trichomonas vaginalis CMGC family protein kinase 0.0766 0.07 0.3199
Trichomonas vaginalis CAMK family protein kinase 0.1457 0.1749 0.8017
Trypanosoma cruzi cdc2-related kinase 3 0.0705 0.0607 0.3458
Schistosoma mansoni protein kinase 0.0826 0.0791 0.1494
Trichomonas vaginalis 3-phosphoinositide dependent protein kinase-1, putative 0.0323 0.0028 0.0109
Echinococcus multilocularis neurotracting:lsamp:neurotrimin:obcam 0.0341 0.0055 0.0038
Loa Loa (eye worm) CMGC/CDK/CDC2 protein kinase 0.0705 0.0607 0.0607
Trichomonas vaginalis AGC family protein kinase 0.1742 0.2181 1
Brugia malayi Protein kinase domain containing protein 0.1742 0.2181 0.2178
Trichomonas vaginalis CMGC family protein kinase 0.0589 0.0432 0.1965
Trypanosoma cruzi STE/STE20 serine/threonine-protein kinase, putative 0.0493 0.0286 0.1618
Trichomonas vaginalis CAMK family protein kinase 0.0451 0.0222 0.1003
Giardia lamblia Kinase, NEK 0.0812 0.0771 0.4027
Leishmania major serine/threonine protein kinase, putative,protein kinase, putative 0.0451 0.0222 0.068
Schistosoma mansoni tyrosine kinase 0.047 0.0252 0.047
Trypanosoma brucei cAMP-dependent protein kinase catalytic subunit 2 0.0545 0.0365 0.1227
Brugia malayi serine/threonine-protein kinase 6 0.1275 0.1472 0.1469
Loa Loa (eye worm) hypothetical protein 0.0341 0.0055 0.0055
Entamoeba histolytica serine/threonine-protein kinase 3, putative 0.0493 0.0286 0.1205
Echinococcus granulosus mitogen activated protein kinase 3 0.0487 0.0277 0.0277
Trichomonas vaginalis CAMK family protein kinase 0.0451 0.0222 0.1003
Trichomonas vaginalis AGC family protein kinase 0.0958 0.0992 0.4539
Loa Loa (eye worm) hypothetical protein 0.127 0.1465 0.1465
Loa Loa (eye worm) camk/mapkapk/mnk protein kinase 0.1871 0.2376 0.2376
Trichomonas vaginalis AGC family protein kinase 0.1742 0.2181 1
Brugia malayi hypothetical protein 0.0429 0.0189 0.0185
Brugia malayi RhoGAP domain containing protein 0.0582 0.0421 0.0417
Echinococcus multilocularis PAK box P21 Rho binding 0.0367 0.0095 0.0092
Loa Loa (eye worm) CMGC/GSK protein kinase 0.0766 0.07 0.07
Brugia malayi Sex muscle abnormal protein 5 0.045 0.022 0.0217
Schistosoma mansoni serine/threonine protein kinase 0.0588 0.043 0.0809
Echinococcus multilocularis tyrosine protein kinase Btk29A 0.1963 0.2517 0.3345
Schistosoma mansoni serine/threonine protein kinase 0.0339 0.0052 0.0092
Loa Loa (eye worm) AUR protein kinase 0.1275 0.1472 0.1472
Echinococcus granulosus roundabout 2 0.0396 0.0139 0.0124
Entamoeba histolytica protein kinase, putative 0.1697 0.2113 0.9685
Loa Loa (eye worm) hypothetical protein 0.0341 0.0055 0.0055
Schistosoma mansoni rac gtpase activating protein 0.0322 0.0027 0.0043
Schistosoma mansoni ste20-related kinase 0.124 0.142 0.2687
Loa Loa (eye worm) CAMK/CAMKL/MELK protein kinase 0.1054 0.1137 0.1137
Trichomonas vaginalis CMGC family protein kinase 0.0405 0.0152 0.0681
Onchocerca volvulus 0.0536 0.0351 0.035
Trypanosoma cruzi casein kinase, delta isoform, putative 0.0389 0.0129 0.0716
Brugia malayi Prion-like- 0.0341 0.0055 0.0051
Echinococcus multilocularis tyrosine protein kinase shark 0.1192 0.1347 0.1774
Schistosoma mansoni serine/threonine protein kinase 0.1655 0.2049 0.3882
Schistosoma mansoni neuroglian 0.0396 0.0139 0.0257
Schistosoma mansoni serine/threonine protein kinase 0.0866 0.0852 0.1609
Echinococcus granulosus serine:threonine protein kinase MARK2 0.1221 0.1391 0.1505
Trichomonas vaginalis CMGC family protein kinase 0.05 0.0297 0.1345
Brugia malayi MAP kinase sur-1 0.0487 0.0277 0.0274
Toxoplasma gondii aurora kinase 0.1275 0.1472 0.6929
Toxoplasma gondii histone kinase SNF1, putative 0.0451 0.0222 0.0938
Loa Loa (eye worm) CAMK/TSSK protein kinase 0.2489 0.3316 0.3316
Loa Loa (eye worm) hypothetical protein 0.0397 0.014 0.014
Schistosoma mansoni serine/threonine kinase 0.0958 0.0992 0.1876
Echinococcus granulosus expressed protein 0.0377 0.0111 0.0093
Echinococcus multilocularis c src tyrosine kinase 0.0726 0.0639 0.0823
Echinococcus multilocularis twitchin 0.0339 0.0052 0.0035
Echinococcus granulosus tyrosine protein kinase Fyn 0.1179 0.1328 0.1434
Echinococcus multilocularis lachesin 0.0341 0.0055 0.0038
Echinococcus granulosus serine:threonine protein kinase Chk2 0.0407 0.0156 0.0143
Loa Loa (eye worm) casein kinase 0.0676 0.0564 0.0564
Plasmodium falciparum serine/threonine protein kinase 0.0377 0.0111 0.0094
Schistosoma mansoni hypothetical protein 0.0546 0.0366 0.0687
Onchocerca volvulus 0.0536 0.0351 0.035
Loa Loa (eye worm) AUR protein kinase 0.1275 0.1472 0.1472
Loa Loa (eye worm) TK/EPH protein kinase 0.0782 0.0724 0.0724
Onchocerca volvulus 0.1018 0.1082 0.117
Plasmodium vivax serine/threonine protein kinase 6, putative 0.1275 0.1472 1
Echinococcus multilocularis myotubularin protein 13 0.0367 0.0094 0.0091
Brugia malayi Immunoglobulin I-set domain containing protein 0.0341 0.0055 0.0051
Trichomonas vaginalis CMGC family protein kinase 0.0405 0.0152 0.0681
Plasmodium falciparum protein kinase, putative 0.0448 0.0218 0.0877
Trichomonas vaginalis CMGC family protein kinase 0.0405 0.0152 0.0681
Echinococcus multilocularis titin 0.0395 0.0137 0.0148
Echinococcus multilocularis mitogen activated protein kinase 11 0.0955 0.0987 0.129
Schistosoma mansoni serine/threonine protein kinase 0.0705 0.0607 0.1146
Echinococcus granulosus mitogen activated protein kinase 14 0.0955 0.0987 0.1059
Echinococcus multilocularis Glutaredoxin protein 5 0.0739 0.0659 0.0849
Brugia malayi Ras association domain family 1 isoform A 0.0322 0.0027 0.0023
Schistosoma mansoni hypothetical protein 0.0322 0.0027 0.0043
Plasmodium falciparum casein kinase 1 0.0562 0.0391 0.2131
Loa Loa (eye worm) camk/dcamkl protein kinase 0.0654 0.0531 0.0531
Schistosoma mansoni serine/threonine protein kinase 0.0946 0.0973 0.184
Loa Loa (eye worm) variant SH3 domain-containing protein 0.045 0.022 0.022
Onchocerca volvulus 0.0766 0.07 0.0742
Plasmodium falciparum RAC-beta serine/threonine protein kinase 0.0911 0.0921 0.5987
Echinococcus granulosus maternal embryonic leucine zipper kinase 0.0508 0.0309 0.0311
Onchocerca volvulus Basement membrane proteoglycan homolog 0.0341 0.0055 0.0018
Plasmodium falciparum cGMP-dependent protein kinase 0.0588 0.043 0.2417
Echinococcus granulosus epidermal growth factor receptor 0.2488 0.3314 0.3625
Plasmodium vivax calcium-dependent protein kinase 3, putative 0.0498 0.0293 0.1615
Loa Loa (eye worm) CAMK/MLCK protein kinase 0.0569 0.0401 0.0401
Plasmodium vivax calcium-dependent protein kinase, putative 0.0498 0.0293 0.1615
Loa Loa (eye worm) AUR protein kinase 0.1275 0.1472 0.1472
Onchocerca volvulus 0.0536 0.0351 0.035
Entamoeba histolytica protein kinase, putative 0.0766 0.07 0.3127
Trichomonas vaginalis AGC family protein kinase 0.0323 0.0028 0.0109
Echinococcus multilocularis tyrosine protein kinase Src42A 0.1179 0.1328 0.1748
Echinococcus multilocularis serine:threonine protein kinase PAK 3 0.0501 0.0299 0.0366
Trypanosoma cruzi cAMP-dependent protein kinase catalytic subunit 3 0.0545 0.0365 0.2068
Plasmodium falciparum calcium-dependent protein kinase 1 0.0498 0.0293 0.1423
Brugia malayi Pleckstrin Homology Domain 0.0367 0.0094 0.0091
Brugia malayi EST embl|AI107989|AI107989 comes from the 3' UTR, putative 0.1048 0.1129 0.1126
Schistosoma mansoni tyrosine kinase 0.2212 0.2895 0.5488
Loa Loa (eye worm) CAMK protein kinase 0.0395 0.0137 0.0137
Loa Loa (eye worm) TK protein kinase 0.1013 0.1076 0.1076
Brugia malayi intracellular kinase 0.0766 0.07 0.0697
Echinococcus multilocularis tyrosine protein kinase Src64B 0.1179 0.1328 0.1748
Echinococcus multilocularis phosphorylase kinase gamma subunit 0.0708 0.0613 0.0787
Echinococcus granulosus casein kinase I alpha 0.0562 0.0391 0.0401
Schistosoma mansoni serine/threonine protein kinase 0.0451 0.0222 0.0414
Brugia malayi Protein kinase domain containing protein 0.0536 0.0351 0.0347
Schistosoma mansoni tyrosine kinase 0.1562 0.1908 0.3614
Onchocerca volvulus 0.0405 0.0152 0.0127
Trichomonas vaginalis CAMK family protein kinase 0.0498 0.0293 0.133
Schistosoma mansoni serine/threonine protein kinase 0.066 0.054 0.1018
Schistosoma mansoni unc-13 (munc13) 0.033 0.0038 0.0066
Loa Loa (eye worm) TK/FER protein kinase 0.0536 0.0351 0.0351
Loa Loa (eye worm) CAMK/CAMKL/CHK1 protein kinase 0.1213 0.1378 0.1378
Entamoeba histolytica hypothetical protein 0.0726 0.064 0.2846
Echinococcus multilocularis serine:threonine protein kinase N2 0.0958 0.0992 0.1297
Loa Loa (eye worm) hypothetical protein 0.0676 0.0564 0.0564
Trichomonas vaginalis CAMK family protein kinase 0.0451 0.0222 0.1003
Schistosoma mansoni protein kinase 0.1275 0.1472 0.2787
Trichomonas vaginalis STE family protein kinase 0.0501 0.0299 0.1356
Schistosoma mansoni serine/threonine-protein kinase 0.0956 0.0989 0.1869
Loa Loa (eye worm) Ras association domain family 1 isoform A 0.0322 0.0027 0.0027
Echinococcus granulosus mitogen activated protein kinase kinase kinase 0.1286 0.1489 0.1612
Brugia malayi Immunoglobulin I-set domain containing protein 0.0341 0.0055 0.0051
Entamoeba histolytica casein kinase, putative 0.0589 0.0432 0.188
Loa Loa (eye worm) CAMK/PKD protein kinase 0.0868 0.0856 0.0856
Schistosoma mansoni serine/threonine protein kinase 0.0666 0.0548 0.1033
Schistosoma mansoni atypical protein kinase C 0.1832 0.2318 0.4392
Plasmodium vivax cAMP-dependent protein kinase catalytic subunit, putative 0.0545 0.0365 0.2123
Entamoeba histolytica PH domain containing protein kinase, putative 0.059 0.0433 0.1885
Plasmodium falciparum NIMA related kinase 1 0.0812 0.0771 0.4895
Onchocerca volvulus 0.0536 0.0351 0.035
Echinococcus multilocularis serine:threonine protein kinase 0.0676 0.0563 0.0721
Echinococcus granulosus casein kinase I gamma 0.0848 0.0825 0.0881
Brugia malayi serine/threonine-protein kinase plk-2 0.1457 0.1749 0.1746
Entamoeba histolytica protein kinase, putative 0.0407 0.0156 0.0602
Echinococcus multilocularis insulin receptor 0.2771 0.3743 0.4992
Echinococcus granulosus serine/threonine protein kinase 0.0956 0.0989 0.1061
Schistosoma mansoni serine/threonine protein kinase 0.1221 0.1391 0.2633
Schistosoma mansoni protein kinase C mu 0.0322 0.0027 0.0043
Loa Loa (eye worm) hypothetical protein 0.1062 0.115 0.115
Schistosoma mansoni protein kinase 0.0448 0.0218 0.0407
Loa Loa (eye worm) TK/EGFR protein kinase 0.3779 0.5272 0.5272
Entamoeba histolytica protein kinase, putative 0.0506 0.0305 0.1293
Trypanosoma cruzi casein kinase, putative 0.0562 0.0391 0.2216
Loa Loa (eye worm) AGC/PDK1 protein kinase 0.0473 0.0256 0.0256
Plasmodium falciparum casein kinase 2, alpha subunit 0.0589 0.0432 0.2429
Trichomonas vaginalis AGC family protein kinase 0.0323 0.0028 0.0109
Brugia malayi Variant SH3 domain containing protein 0.0312 0.0012 0.0008
Brugia malayi Protein kinase domain containing protein 0.2489 0.3316 0.3313
Loa Loa (eye worm) TKL/RAF/RAF protein kinase 0.1665 0.2064 0.2064
Echinococcus multilocularis protein tyrosine kinase 0.2344 0.3095 0.4121
Echinococcus multilocularis receptor type tyrosine protein phosphatase 0.0396 0.0139 0.0151
Echinococcus multilocularis casein kinase I delta 0.0562 0.0391 0.0489
Loa Loa (eye worm) hypothetical protein 0.0493 0.0286 0.0286
Echinococcus multilocularis tyrosine protein kinase otk 0.0341 0.0055 0.0038
Trichomonas vaginalis AGC family protein kinase 0.0323 0.0028 0.0109
Loa Loa (eye worm) hypothetical protein 0.0732 0.0648 0.0648
Echinococcus multilocularis 5' AMP activated protein kinase catalytic 0.1048 0.1129 0.1481
Leishmania major casein kinase, putative 0.0562 0.0391 0.1708
Trypanosoma cruzi kinetoplastid kinetochore protein 10, putative 0.0666 0.0548 0.3118
Entamoeba histolytica protein kinase 2, putative 0.0911 0.0921 0.4151
Leishmania major protein kinase, putative 0.0498 0.0293 0.1114
Echinococcus granulosus dual specificity 0.05 0.0297 0.0298
Giardia lamblia Kinase, AGC PKA 0.0911 0.0921 0.4944
Echinococcus multilocularis c Jun NH2 terminal kinase 0.1607 0.1976 0.2618
Brugia malayi Protein kinase domain containing protein 0.0536 0.0351 0.0347
Schistosoma mansoni tyrosine kinase 0.0726 0.0639 0.1206
Schistosoma mansoni nck2/grb4 0.045 0.022 0.0411
Brugia malayi protein kinase C3,putative 0.1008 0.1068 0.1065
Loa Loa (eye worm) CMGC/CDK/CDK5 protein kinase 0.0705 0.0607 0.0607
Brugia malayi Protein kinase domain containing protein 0.1054 0.1137 0.1133
Schistosoma mansoni serine/threonine protein kinase 0.0958 0.0992 0.1876
Echinococcus granulosus 5'partial|cyclin dependent kinase 1 0.0705 0.0607 0.064
Brugia malayi diacylglycerol kinase 0.0322 0.0027 0.0023
Schistosoma mansoni unc-13 (munc13) 0.033 0.0038 0.0066
Entamoeba histolytica protein kinase domain containing protein 0.0726 0.064 0.2846
Echinococcus granulosus casein kinase I alpha 0.0562 0.0391 0.0401
Schistosoma mansoni serine/threonine protein kinase 0.0377 0.0111 0.0203
Echinococcus granulosus tyrosine protein kinase Src42A 0.1179 0.1328 0.1434
Brugia malayi Cam kinase protein 1 0.0498 0.0293 0.029
Giardia lamblia Kinase, CDC7 0.0405 0.0152 0.0252
Plasmodium vivax unspecified product 0.0589 0.0432 0.2598
Trypanosoma brucei protein kinase, putative 0.0766 0.07 0.2848
Echinococcus granulosus calcium:calmodulin dependent protein kinase 0.0911 0.0921 0.0986
Loa Loa (eye worm) hypothetical protein 0.1022 0.1089 0.1089
Entamoeba histolytica protein kinase domain containing protein 0.0866 0.0852 0.3831
Entamoeba histolytica protein kinase domain containing protein 0.0589 0.0432 0.188
Brugia malayi Egg laying defective protein 4 0.0588 0.043 0.0426
Echinococcus granulosus tyrosine protein kinase otk 0.0341 0.0055 0.0031
Giardia lamblia Kinase, STE STE20 0.0501 0.0299 0.1149
Echinococcus multilocularis cAMP dependent protein kinase catalytic subunit 0.0545 0.0365 0.0454
Loa Loa (eye worm) AGC/PKA protein kinase 0.0545 0.0365 0.0365
Echinococcus granulosus hemicentin 1 0.0341 0.0055 0.0031
Entamoeba histolytica SH2-protein kinase domain containing protein 0.0536 0.0351 0.1505
Loa Loa (eye worm) hypothetical protein 0.0329 0.0037 0.0037
Echinococcus granulosus dual specificity protein kinase clk2 0.0666 0.0548 0.0575
Schistosoma mansoni protein kinase 0.1092 0.1196 0.2262
Echinococcus granulosus casein kinase ii subunit alpha 0.0589 0.0432 0.0447
Trypanosoma brucei mitogen-activated protein kinase 3, putative 0.0955 0.0987 0.4232
Brugia malayi SH2 domain containing protein 0.1298 0.1507 0.1504
Echinococcus multilocularis serine:threonine protein kinase Chk2 0.0407 0.0156 0.0174
Entamoeba histolytica serine/threonine- protein kinase 6, putative 0.1275 0.1472 0.6711
Loa Loa (eye worm) CAMK/CAMK2 protein kinase 0.0498 0.0293 0.0293
Loa Loa (eye worm) hypothetical protein 0.0554 0.0378 0.0378
Loa Loa (eye worm) AGC/PKG protein kinase 0.0588 0.043 0.043
Loa Loa (eye worm) hypothetical protein 0.0322 0.0027 0.0027
Loa Loa (eye worm) AGC/NDR protein kinase 0.0958 0.0992 0.0992
Echinococcus multilocularis N chimaerin 0.0582 0.0421 0.0529
Entamoeba histolytica protein kinase domain containing protein 0.1275 0.1472 0.6711
Brugia malayi Protein kinase domain containing protein 0.1286 0.1489 0.1486
Brugia malayi P38 map kinase family protein 2 0.0955 0.0987 0.0983
Brugia malayi serine/threonine kinase 12 0.1275 0.1472 0.1469
Loa Loa (eye worm) TK/FER protein kinase 0.0536 0.0351 0.0351
Echinococcus granulosus dual specificity 0.05 0.0297 0.0298
Echinococcus multilocularis ephrin type A receptor 4 A 0.0673 0.0559 0.0715
Brugia malayi Protein kinase domain 0.0501 0.0299 0.0295
Toxoplasma gondii calcium dependent protein kinase CDPK8 0.0448 0.0218 0.0919
Trichomonas vaginalis CMGC family protein kinase 0.0589 0.0432 0.1965
Schistosoma mansoni serine/threonine protein kinase 0.0958 0.0992 0.1876
Trypanosoma cruzi mitogen-activated protein kinase 3, putative 0.0955 0.0987 0.5632
Echinococcus multilocularis activin receptor type 0.0448 0.0218 0.0258
Echinococcus multilocularis calcium:calmodulin dependent protein kinase type 0.0498 0.0293 0.0358
Echinococcus granulosus ribosomal protein S6 kinase alpha 3 0.148 0.1783 0.1937
Echinococcus multilocularis death associated protein kinase 1 0.5228 0.7471 1
Echinococcus multilocularis serine threonine protein kinase 0.1212 0.1377 0.1814
Echinococcus granulosus mitogen activated protein kinase 0.0487 0.0277 0.0277
Brugia malayi protein-tyrosine kinase 0.0989 0.1039 0.1036
Schistosoma mansoni serine/threonine protein kinase 0.1538 0.1872 0.3546
Echinococcus granulosus casein kinase I delta 0.0562 0.0391 0.0401
Echinococcus granulosus guanine nucleotide exchange factor VAV2 0.0582 0.0421 0.0435
Echinococcus granulosus serine:threonine protein kinase PLK1 0.1457 0.1749 0.1899
Echinococcus multilocularis casein kinase I gamma 0.0848 0.0825 0.1073
Echinococcus granulosus rho-associated protein kinase 1 0.1837 0.2325 0.2534
Giardia lamblia Kinase, NEK 0.0812 0.0771 0.4027
Schistosoma mansoni serine/threonine-protein kinase 0.0956 0.0989 0.1869
Echinococcus granulosus casein kinase I delta 0.0562 0.0391 0.0401
Echinococcus granulosus N chimaerin 0.0582 0.0421 0.0435
Loa Loa (eye worm) AGC/DMPK/ROCK protein kinase 0.535 0.7656 0.7656
Entamoeba histolytica protein kinase, putative 0.0501 0.0299 0.1264
Trichomonas vaginalis CAMK family protein kinase 0.1457 0.1749 0.8017
Trypanosoma cruzi mitogen-activated protein kinase 3, putative 0.0955 0.0987 0.5632
Echinococcus granulosus 3'partial|tyrosine protein kinase Fgr 0.1179 0.1328 0.1434
Loa Loa (eye worm) TK/FER protein kinase 0.0536 0.0351 0.0351
Loa Loa (eye worm) hypothetical protein 0.0767 0.0703 0.0703
Echinococcus granulosus c src tyrosine kinase 0.0726 0.0639 0.0675
Brugia malayi Protein kinase domain containing protein 0.0848 0.0825 0.0822
Loa Loa (eye worm) AGC/DMPK/GEK protein kinase 0.2058 0.2662 0.2662
Trichomonas vaginalis CAMK family protein kinase 0.0451 0.0222 0.1003
Brugia malayi Protein kinase domain containing protein 0.0405 0.0152 0.0148
Giardia lamblia Kinase, AGC PKA 0.0545 0.0365 0.1551
Echinococcus multilocularis tyrosine protein kinase Fyn 0.1179 0.1328 0.1748
Schistosoma mansoni protein kinase C mu 0.119 0.1344 0.2544
Loa Loa (eye worm) hypothetical protein 0.086 0.0844 0.0844
Loa Loa (eye worm) RhoGAP domain-containing protein 0.0582 0.0421 0.0421
Loa Loa (eye worm) CAMK/MLCK protein kinase 0.0395 0.0137 0.0137
Schistosoma mansoni protein kinase 0.0367 0.0095 0.0173
Leishmania major protein kinase, putative 0.0493 0.0286 0.1071
Loa Loa (eye worm) CAMK/CAMKL/AMPK protein kinase 0.1048 0.1129 0.1129
Schistosoma mansoni cell adhesion molecule 0.0396 0.0139 0.0257
Echinococcus granulosus c-Jun N-terminal kinases 0.1607 0.1976 0.2149
Brugia malayi Fibronectin type III domain containing protein 0.0732 0.0648 0.0645
Schistosoma mansoni serine/threonine protein kinase 0.1224 0.1395 0.2641
Loa Loa (eye worm) CMGC/MAPK/JNK protein kinase 0.1607 0.1976 0.1976
Loa Loa (eye worm) variant SH3 domain-containing protein 0.0312 0.0012 0.0012
Loa Loa (eye worm) AGC/PKC/ALPHA protein kinase 0.0426 0.0185 0.0185
Trichomonas vaginalis AGC family protein kinase 0.0473 0.0256 0.1159
Entamoeba histolytica protein kinase, putative 0.0473 0.0256 0.1066
Entamoeba histolytica SH2-protein kinase domain containing protein 0.0432 0.0194 0.0777
Loa Loa (eye worm) hypothetical protein 0.1018 0.1082 0.1082
Echinococcus granulosus insulin receptor 0.2771 0.3743 0.4098
Trypanosoma cruzi aurora B kinase, putative 0.1275 0.1472 0.8413
Entamoeba histolytica protein kinase domain containing protein 0.05 0.0297 0.1253
Echinococcus multilocularis serine:threonine protein kinase TAO1 0.0946 0.0973 0.1272
Onchocerca volvulus 0.0429 0.0189 0.0168
Schistosoma mansoni serine/threonine protein kinase 0.0621 0.048 0.0904
Trichomonas vaginalis CMGC family protein kinase 0.05 0.0297 0.1345
Trichomonas vaginalis AGC family protein kinase 0.0323 0.0028 0.0109
Loa Loa (eye worm) hypothetical protein 0.0341 0.0055 0.0055
Onchocerca volvulus 0.1062 0.115 0.1246
Trichomonas vaginalis AGC family protein kinase 0.0323 0.0028 0.0109
Echinococcus granulosus cyclin dependent kinase 1 0.0705 0.0607 0.064
Brugia malayi Protein kinase domain containing protein 0.0536 0.0351 0.0347
Toxoplasma gondii AGC kinase 0.0545 0.0365 0.1621
Echinococcus multilocularis tyrosine protein kinase Fgr 0.1179 0.1328 0.1748
Toxoplasma gondii cell-cycle-associated protein kinase CDK, putative 0.0705 0.0607 0.2784
Loa Loa (eye worm) hypothetical protein 0.0554 0.0378 0.0378
Trichomonas vaginalis CAMK family protein kinase 0.1457 0.1749 0.8017
Trichomonas vaginalis CAMK family protein kinase 0.0451 0.0222 0.1003
Trichomonas vaginalis AGC family protein kinase 0.0323 0.0028 0.0109
Brugia malayi putative serine/threonine kinase SADA gamma 0.0451 0.0222 0.0218
Brugia malayi hypothetical protein 0.0946 0.0973 0.097
Echinococcus granulosus cGMP dependent protein kinase 1 0.0588 0.043 0.0445
Echinococcus granulosus peroxidasin 0.0342 0.0057 0.0034
Echinococcus granulosus macrophage colony stimulating factor 1 receptor 0.6299 0.9096 1
Echinococcus granulosus tyrosine protein kinase 0.1013 0.1076 0.1157
Loa Loa (eye worm) hypothetical protein 0.0696 0.0594 0.0594
Schistosoma mansoni tyrosine kinase 0.1179 0.1328 0.2513
Trichomonas vaginalis CMGC family protein kinase 0.0666 0.0548 0.25
Loa Loa (eye worm) STE/STE20/KHS protein kinase 0.1286 0.1489 0.1489
Echinococcus granulosus nervana 2 0.0739 0.0659 0.0697
Trypanosoma brucei cAMP-dependent protein kinase catalytic subunit 1 0.0545 0.0365 0.1227
Echinococcus granulosus GTPase activating Rap:RanGAP domain 3 0.0429 0.0189 0.0179
Brugia malayi phosphoinositide-dependent protein kinase I 0.0473 0.0256 0.0253
Brugia malayi Serine/threonine-protein kinase SULU 0.0946 0.0973 0.097
Brugia malayi Protein kinase domain containing protein 0.0705 0.0607 0.0604
Echinococcus multilocularis calcium dependent protein kinase 0.0325 0.0031 0.0007
Trypanosoma cruzi mitogen activated protein kinase 2, putative 0.0487 0.0277 0.1568
Plasmodium vivax casein kinase 2, alpha subunit, putative 0.0589 0.0432 0.2598
Toxoplasma gondii AGC kinase 0.0545 0.0365 0.1621
Schistosoma mansoni tyrosine kinase 0.2771 0.3743 0.7097
Trypanosoma cruzi mitogen-activated protein kinase 11, putative 0.0487 0.0277 0.1568
Brugia malayi protein unc-22 0.0395 0.0137 0.0133
Brugia malayi Hr1 repeat family protein 0.1488 0.1796 0.1793
Entamoeba histolytica p21-activated kinase 0.0546 0.0367 0.1579
Loa Loa (eye worm) camk/mapkapk/mapkapk protein kinase 0.2412 0.3198 0.3198
Entamoeba histolytica protein kinase, putative 0.1275 0.1472 0.6711
Loa Loa (eye worm) thyroid receptor interactor 0.0496 0.0291 0.0291
Loa Loa (eye worm) CAMK/PIM protein kinase 0.1655 0.2049 0.2049
Trypanosoma cruzi casein kinase, putative 0.0562 0.0391 0.2216
Echinococcus granulosus serine:threonine protein kinase N2 0.053 0.0342 0.0348
Loa Loa (eye worm) CAMK/PHK protein kinase 0.0708 0.0613 0.0613
Echinococcus multilocularis 0.0493 0.0286 0.0349
Echinococcus granulosus fibroblast growth factor receptor 4 0.1505 0.1822 0.1979
Echinococcus granulosus contactin 0.0396 0.0139 0.0124
Giardia lamblia Kinase, CMGC CLK 0.0666 0.0548 0.2669
Schistosoma mansoni serine/threonine protein kinase 0.1221 0.1391 0.2633
Loa Loa (eye worm) hypothetical protein 0.0696 0.0594 0.0594
Loa Loa (eye worm) hypothetical protein 0.0341 0.0055 0.0055
Loa Loa (eye worm) hypothetical protein 0.086 0.0844 0.0844
Trichomonas vaginalis AGC family protein kinase 0.0323 0.0028 0.0109
Toxoplasma gondii cell-cycle-associated protein kinase SRPK, putative 0.0377 0.0111 0.0403
Schistosoma mansoni titin 0.0395 0.0137 0.0253
Leishmania major protein kinase A catalytic subunit isoform 1 0.0545 0.0365 0.1551
Echinococcus granulosus activin receptor type 0.0448 0.0218 0.0211
Echinococcus granulosus cGMP dependent protein kinase 1 0.0588 0.043 0.0445
Loa Loa (eye worm) TK protein kinase 0.073 0.0645 0.0645
Echinococcus multilocularis unc 13 (munc13) 0.033 0.0038 0.0016
Brugia malayi ribosomal protein S6 kinase alpha 3 0.0694 0.0591 0.0588
Echinococcus multilocularis growth factor receptor bound protein 2 0.045 0.022 0.0261
Brugia malayi Tyrosine-protein kinase abl-1 0.1217 0.1385 0.1382
Echinococcus multilocularis hypothetical protein 0.0546 0.0366 0.0456
Trichomonas vaginalis AGC family protein kinase 0.1064 0.1152 0.5274
Trypanosoma brucei Casein kinase II 0.0589 0.0432 0.155
Leishmania major protein kinase, putative,dual-specificity protein kinase, putative 0.05 0.0297 0.1134
Brugia malayi Homeodomain interacting protein kinase protein 1 0.0866 0.0852 0.0848
Trichomonas vaginalis CK1 family protein kinase 0.0562 0.0391 0.1777
Onchocerca volvulus 0.5769 0.8292 0.9248
Plasmodium vivax casein kinase 1, putative 0.0562 0.0391 0.2307
Loa Loa (eye worm) hypothetical protein 0.0341 0.0055 0.0055
Echinococcus granulosus dual specificity 0.05 0.0297 0.0298
Trichomonas vaginalis AGC family protein kinase 0.0323 0.0028 0.0109
Brugia malayi Protein kinase domain containing protein 0.0826 0.0791 0.0787
Trypanosoma brucei SNF1-related protein kinases, putative 0.0451 0.0222 0.0539
Trypanosoma cruzi Protein kinase B 0.0956 0.0989 0.5642
Trichomonas vaginalis CAMK family protein kinase 0.0676 0.0563 0.257
Echinococcus multilocularis p21 activated protein kinase 1 Dpak1 0.0501 0.0299 0.0366
Schistosoma mansoni proto-oncogene tyrosine-protein kinase abl1 0.045 0.022 0.0411
Loa Loa (eye worm) immunoglobulin I-set domain-containing protein 0.0341 0.0055 0.0055
Brugia malayi Variant SH3 domain containing protein 0.045 0.022 0.0217
Trypanosoma cruzi casein kinase, delta isoform, putative 0.0562 0.0391 0.2216
Echinococcus multilocularis tyrosine protein kinase Blk 0.0989 0.1039 0.136
Echinococcus multilocularis mitogen activated protein kinase 0.0487 0.0277 0.0337
Toxoplasma gondii cell-cycle-associated protein kinase CLK, putative 0.0666 0.0548 0.25
Schistosoma mansoni serine/threonine protein kinase 0.1048 0.1129 0.2136
Schistosoma mansoni serine/threonine protein kinase 0.0708 0.0613 0.1156
Echinococcus multilocularis tyrosine protein kinase Fyn 0.0989 0.1039 0.136
Schistosoma mansoni cell adhesion molecule 0.0341 0.0055 0.0097
Entamoeba histolytica protein kinase, putative 0.0498 0.0293 0.1238
Trypanosoma brucei protein kinase A catalytic subunit, putative 0.0545 0.0365 0.1227
Echinococcus multilocularis casein kinase I alpha 0.0562 0.0391 0.0489
Trypanosoma cruzi rac serine-threonine kinase, putative 0.0911 0.0921 0.5253
Echinococcus granulosus calcium:calmodulin dependent protein kinase I 0.0407 0.0156 0.0143
Loa Loa (eye worm) immunoglobulin I-set domain-containing protein 0.0396 0.0139 0.0139
Trypanosoma brucei mitogen activated protein kinase 4, putative 0.0487 0.0277 0.0806
Trypanosoma brucei dual specificity tyrosine-phosphorylation-regulated kinase 2, putative 0.05 0.0297 0.0898
Echinococcus multilocularis serine:threonine protein kinase 3 0.156 0.1906 0.2525
Echinococcus multilocularis dual specificity protein kinase clk2 0.0666 0.0548 0.07
Echinococcus granulosus nervana 2 0.0739 0.0659 0.0697
Loa Loa (eye worm) hypothetical protein 0.0738 0.0657 0.0657
Schistosoma mansoni serine/threonine protein kinase 0.0705 0.0607 0.1146
Trichomonas vaginalis STE family protein kinase 0.0501 0.0299 0.1356
Trypanosoma cruzi dual specificity tyrosine-phosphorylation-regulated kinase 2, putative 0.05 0.0297 0.1677
Loa Loa (eye worm) CK1/CK1/CK1-A protein kinase 0.0562 0.0391 0.0391
Trypanosoma cruzi cdc2-related kinase 3 0.0705 0.0607 0.3458
Entamoeba histolytica serine/threonine protein kinase 6, putative 0.1275 0.1472 0.6711
Plasmodium vivax serine/threonine protein kinase, putative 0.0377 0.0111 0.0316
Loa Loa (eye worm) hypothetical protein 0.1022 0.1089 0.1089
Trichomonas vaginalis AGC family protein kinase 0.0323 0.0028 0.0109
Loa Loa (eye worm) immunoglobulin I-set domain-containing protein 0.0341 0.0055 0.0055
Trichomonas vaginalis CAMK family protein kinase 0.1457 0.1749 0.8017
Schistosoma mansoni hypothetical protein 0.0429 0.0189 0.0351
Echinococcus granulosus Serine:threonine protein kinase PLK4 0.0866 0.0852 0.091
Loa Loa (eye worm) hypothetical protein 0.0732 0.0648 0.0648
Trichomonas vaginalis CAMK family protein kinase 0.1457 0.1749 0.8017
Schistosoma mansoni cell adhesion molecule 0.0906 0.0912 0.1724
Trichomonas vaginalis AGC family protein kinase 0.1108 0.122 0.5586
Brugia malayi Raf kinase 0.2649 0.3557 0.3555
Onchocerca volvulus 0.0373 0.0104 0.0074
Echinococcus multilocularis STE20 serine:threonine protein kinase 0.2058 0.2661 0.3538
Schistosoma mansoni neurotracting/lsamp/neurotrimin/obcam related cell adhesion molecule 0.0341 0.0055 0.0097
Echinococcus granulosus enhancer of mRNA decapping protein 4 0.0372 0.0103 0.0084
Schistosoma mansoni protein kinase 0.0589 0.0432 0.0812
Schistosoma mansoni serine/threonine protein kinase 0.1275 0.1472 0.2787
Entamoeba histolytica hypothetical protein 0.1553 0.1895 0.8671
Echinococcus multilocularis casein kinase i 0.0562 0.0391 0.0489
Echinococcus granulosus MAP kinase activated protein kinase 2 0.2412 0.3198 0.3497
Schistosoma mansoni serine/threonine kinase 0.1054 0.1137 0.215
Schistosoma mansoni serine/threonine protein kinase 0.0726 0.064 0.1207
Schistosoma mansoni tyrosine kinase 0.2771 0.3743 0.7097
Echinococcus multilocularis glycogen synthase kinase 3 beta 0.0766 0.07 0.0905
Loa Loa (eye worm) STE/STE20/PAKA protein kinase 0.0307 0.0004 0.0004
Brugia malayi Protein kinase domain containing protein 0.535 0.7656 0.7655
Schistosoma mansoni tyrosine kinase 0.0616 0.0473 0.0891
Leishmania major protein kinase, putative 0.0666 0.0548 0.2669
Schistosoma mansoni serine/threonine protein kinase 0.0473 0.0256 0.0479
Brugia malayi Protein kinase domain containing protein 0.0536 0.0351 0.0347
Echinococcus granulosus cAMP dependent protein kinase catalytic subunit 0.0545 0.0365 0.0373
Schistosoma mansoni protein kinase 0.1259 0.1448 0.2742
Trypanosoma cruzi cAMP-dependent protein kinase catalytic subunit 2 0.0545 0.0365 0.2068
Trichomonas vaginalis CAMK family protein kinase 0.0451 0.0222 0.1003
Loa Loa (eye worm) AGC/PKC/ETA protein kinase 0.1288 0.1492 0.1492
Trichomonas vaginalis AGC family protein kinase 0.0323 0.0028 0.0109
Loa Loa (eye worm) hypothetical protein 0.0737 0.0657 0.0657
Entamoeba histolytica protein kinase, putative 0.0958 0.0992 0.4482
Trichomonas vaginalis CMGC family protein kinase 0.05 0.0297 0.1345
Loa Loa (eye worm) TK/ROR protein kinase 0.0442 0.0209 0.0209
Trypanosoma cruzi casein kinase, putative 0.0562 0.0391 0.2216
Loa Loa (eye worm) AGC/AKT protein kinase 0.1742 0.2181 0.2181
Echinococcus granulosus NCK adaptor protein 0.045 0.022 0.0214
Plasmodium vivax calcium-dependent protein kinase 4, putative 0.0498 0.0293 0.1615
Leishmania major protein kinase A catalytic subunit isoform 2 0.0545 0.0365 0.1551
Brugia malayi Protein kinase domain containing protein 0.1719 0.2147 0.2144
Echinococcus multilocularis Ribosomal protein S6 kinase beta 2 0.0958 0.0992 0.1297
Giardia lamblia Kinase, CK1 Casein kinase 0.0562 0.0391 0.1708
Echinococcus granulosus 3-phosphoinositide-dependent protein kinase 1 0.0473 0.0256 0.0253
Trypanosoma cruzi rac serine-threonine kinase, putative 0.0956 0.0989 0.5642
Echinococcus granulosus aurora kinase A 0.1275 0.1472 0.1594
Echinococcus multilocularis calcium:calmodulin dependent protein kinase type 0.1859 0.2358 0.3132
Trichomonas vaginalis CAMK family protein kinase 0.0451 0.0222 0.1003
Brugia malayi hypothetical protein 0.0536 0.0351 0.0347
Brugia malayi Temporarily assigned gene name protein 59 0.08 0.0752 0.0748
Echinococcus granulosus serine:threonine protein kinase N2 0.1488 0.1796 0.1951
Echinococcus multilocularis serine:threonine protein kinase 12 B 0.1275 0.1472 0.1942
Echinococcus granulosus serine:threonine kinase SAD 1 0.0451 0.0222 0.0216
Loa Loa (eye worm) hypothetical protein 0.0322 0.0027 0.0027
Schistosoma mansoni serine/threonine protein kinase 0.0395 0.0137 0.0253
Trypanosoma cruzi mitogen activated protein kinase 4, putative 0.0487 0.0277 0.1568
Schistosoma mansoni roundabout 0.0341 0.0055 0.0097
Plasmodium vivax NIMA-related protein kinase (Pfnek-1), putative 0.0812 0.0771 0.5009
Schistosoma mansoni tyrosine kinase 0.2488 0.3314 0.6283
Trichomonas vaginalis CAMK family protein kinase 0.0451 0.0222 0.1003
Schistosoma mansoni adapter molecule crk 0.045 0.022 0.0411
Echinococcus multilocularis casein kinase I delta 0.0562 0.0391 0.0489
Loa Loa (eye worm) hypothetical protein 0.0429 0.0189 0.0189
Echinococcus multilocularis aurora kinase A 0.1275 0.1472 0.1942
Echinococcus granulosus basic fibroblast growth factor receptor 1 A 0.1505 0.1822 0.1979
Trypanosoma brucei STE/STE11 serine/threonine-protein kinase, putative 0.0448 0.0218 0.052
Schistosoma mansoni serine/threonine protein kinase 0.0451 0.0222 0.0414
Schistosoma mansoni protein kinase 0.1859 0.2358 0.4469
Echinococcus granulosus tyrosine kinase|tyrosine protein kinase Fyn 0.0989 0.1039 0.1117
Trypanosoma cruzi STE/STE11 serine/threonine-protein kinase, putative 0.0448 0.0218 0.1229
Echinococcus multilocularis nervana 2 0.0739 0.0659 0.0849
Brugia malayi Immunoglobulin I-set domain containing protein 0.0395 0.0137 0.0133
Loa Loa (eye worm) AGC/PKA protein kinase 0.0545 0.0365 0.0365
Trichomonas vaginalis CMGC family protein kinase 0.0705 0.0607 0.2773
Echinococcus multilocularis peroxidasin 0.0342 0.0057 0.0041
Schistosoma mansoni serine/threonine protein kinase 0.0848 0.0825 0.1559
Loa Loa (eye worm) hypothetical protein 0.092 0.0934 0.0934
Brugia malayi Immunoglobulin I-set domain containing protein 0.0341 0.0055 0.0051
Echinococcus multilocularis homeodomain interacting protein kinase 3 0.0866 0.0852 0.1108
Trypanosoma cruzi serine/arginine-rich protein specific kinase SRPK, putative 0.0377 0.0111 0.0612
Loa Loa (eye worm) hypothetical protein 0.0545 0.0365 0.0365
Entamoeba histolytica protein kinase, putative 0.1275 0.1472 0.6711
Echinococcus multilocularis serine:threonine protein kinase MARK2 0.1221 0.1391 0.1833
Loa Loa (eye worm) hypothetical protein 0.0322 0.0027 0.0027
Schistosoma mansoni serine/threonine protein kinase 0.1534 0.1865 0.3533
Trypanosoma brucei 5'-AMP-activated protein kinase catalytic subunit alpha, putative 0.0451 0.0222 0.0539
Echinococcus multilocularis NCK adaptor protein 0.0456 0.023 0.0273
Echinococcus multilocularis Immunoglobulin 0.0676 0.0564 0.0721
Schistosoma mansoni serine/threonine protein kinase 0.0857 0.0838 0.1584
Echinococcus granulosus tyrosine protein kinase Fyn 0.1179 0.1328 0.1434
Echinococcus granulosus epidermal growth factor receptor 0.3779 0.5272 0.5784
Giardia lamblia Kinase, CMGC CDK 0.0705 0.0607 0.3032
Loa Loa (eye worm) hypothetical protein 0.0322 0.0027 0.0027
Brugia malayi Serine/threonine-protein kinase Pim-3 0.1655 0.2049 0.2046
Echinococcus granulosus Ribosomal protein S6 kinase beta 2 0.0958 0.0992 0.1064
Schistosoma mansoni serine/threonine protein kinase 0.0451 0.0222 0.0414
Trichomonas vaginalis CAMK family protein kinase 0.1457 0.1749 0.8017
Schistosoma mansoni protein kinase 0.1859 0.2358 0.4469
Loa Loa (eye worm) hypothetical protein 0.0676 0.0564 0.0564
Schistosoma mansoni protein kinase 0.0501 0.0299 0.056
Schistosoma mansoni vesicular amine transporter 0.0676 0.0564 0.1063
Echinococcus granulosus serine:threonine protein kinase PAK 3 0.0501 0.0299 0.03
Brugia malayi Variant SH3 domain containing protein 0.0582 0.0421 0.0417
Trichomonas vaginalis AGC family protein kinase 0.0323 0.0028 0.0109
Echinococcus multilocularis rac serine:threonine kinase 0.0956 0.0989 0.1292
Leishmania major casein kinase II, putative 0.0589 0.0432 0.1958
Brugia malayi Protein kinase domain containing protein 0.1871 0.2376 0.2374
Trypanosoma cruzi STE/STE11 serine/threonine-protein kinase, putative 0.0448 0.0218 0.1229
Schistosoma mansoni serine/threonine protein kinase 0.0718 0.0628 0.1184
Echinococcus multilocularis casein kinase I alpha 0.0562 0.0391 0.0489
Loa Loa (eye worm) CDC7 protein kinase 0.0405 0.0152 0.0152
Schistosoma mansoni kinase 0.1664 0.2062 0.3907
Echinococcus granulosus Serine/threonine-protein kinase Genghis Khan 0.1224 0.1395 0.1509
Echinococcus granulosus tyrosine protein kinase Srms 0.179 0.2254 0.2456
Leishmania major protein kinase, putative 0.0666 0.0548 0.2669
Onchocerca volvulus 0.0536 0.0351 0.035
Schistosoma mansoni serine/threonine protein kinase 0.1457 0.1749 0.3313
Echinococcus multilocularis maternal embryonic leucine zipper kinase 0.0508 0.0309 0.0379
Echinococcus granulosus protein kinase C gamma type 0.1212 0.1377 0.1489
Echinococcus multilocularis dual specificity 0.05 0.0297 0.0363
Echinococcus multilocularis insulin growth factor 1 receptor beta 0.2827 0.3827 0.5106
Echinococcus multilocularis GTPase activating Rap:RanGAP domain 3 0.0429 0.0189 0.0218
Trypanosoma cruzi SNF1-related protein kinases, putative 0.0451 0.0222 0.1251
Loa Loa (eye worm) TK/FER protein kinase 0.0536 0.0351 0.0351
Echinococcus granulosus dual specificity 0.0726 0.064 0.0676
Echinococcus granulosus calcium dependent protein kinase 0.0325 0.0031 0.0005
Brugia malayi SH2 domain containing protein 0.0536 0.0351 0.0347
Trichomonas vaginalis AGC family protein kinase 0.0812 0.0771 0.3522
Schistosoma mansoni tyrosine kinase 0.1779 0.2237 0.424
Loa Loa (eye worm) CMGC/MAPK/ERK1 protein kinase 0.0487 0.0277 0.0277
Brugia malayi Immunoglobulin I-set domain containing protein 0.0341 0.0055 0.0051
Schistosoma mansoni serine/threonine protein kinase 0.1213 0.1378 0.2609
Trypanosoma cruzi cAMP-dependent protein kinase catalytic subunit 3 0.0545 0.0365 0.2068
Trichomonas vaginalis CMGC family protein kinase 0.05 0.0297 0.1345
Echinococcus multilocularis epidermal growth factor receptor 0.3779 0.5272 0.7047
Toxoplasma gondii AGC kinase 0.1697 0.2113 1
Schistosoma mansoni serine/threonine protein kinase 0.1224 0.1395 0.2641
Echinococcus granulosus STE20 serine:threonine protein kinase 0.2058 0.2661 0.2904
Brugia malayi RhoGEF domain containing protein 0.0322 0.0027 0.0023
Echinococcus multilocularis calcium:calmodulin dependent protein kinase type 0.0498 0.0293 0.0358
Echinococcus multilocularis 0.1077 0.1172 0.1538
Brugia malayi Immunoglobulin I-set domain containing protein 0.0732 0.0648 0.0645
Loa Loa (eye worm) CAMK/PIM protein kinase 0.1655 0.2049 0.2049
Loa Loa (eye worm) hypothetical protein 0.0322 0.0027 0.0027
Entamoeba histolytica cell division protein kinase 2, putative 0.0705 0.0607 0.2696
Loa Loa (eye worm) protein kinase domain-containing protein 0.0848 0.0825 0.0825
Schistosoma mansoni serine/threonine protein kinase 0.1488 0.1796 0.3401
Echinococcus granulosus insulin growth factor 1 receptor beta 0.2827 0.3827 0.4191
Giardia lamblia Kinase, CMGC DYRK 0.05 0.0297 0.1134
Echinococcus multilocularis hemicentin 1 0.0341 0.0055 0.0038
Loa Loa (eye worm) AGC/PDK1 protein kinase 0.0473 0.0256 0.0256
Toxoplasma gondii calcium-dependent protein kinase CDPK3 0.0498 0.0293 0.1278
Loa Loa (eye worm) hypothetical protein 0.0677 0.0566 0.0566
Loa Loa (eye worm) hypothetical protein 0.0367 0.0094 0.0094
Loa Loa (eye worm) TK protein kinase 0.1038 0.1113 0.1113
Echinococcus multilocularis mitogen activated protein kinase kinase kinase 0.0601 0.045 0.0569
Trichomonas vaginalis STE family protein kinase 0.0501 0.0299 0.1356
Loa Loa (eye worm) AGC/PKN protein kinase 0.1488 0.1796 0.1796
Plasmodium falciparum calcium-dependent protein kinase 3 0.0498 0.0293 0.1423
Brugia malayi protein kinase C II. 0.1288 0.1492 0.1489
Echinococcus granulosus 5' AMP activated protein kinase catalytic 0.1048 0.1129 0.1216
Echinococcus multilocularis calcium:calmodulin dependent protein kinase type 0.0498 0.0293 0.0358
Trypanosoma brucei protein kinase, putative 0.0448 0.0218 0.052
Trypanosoma brucei protein kinase, putative 0.0487 0.0277 0.0806
Schistosoma mansoni tyrosine kinase 0.0726 0.0639 0.1206
Trichomonas vaginalis CMGC family protein kinase 0.0589 0.0432 0.1965
Echinococcus multilocularis guanine nucleotide exchange factor VAV2 0.0582 0.0421 0.0529
Trypanosoma cruzi casein kinase, putative 0.0562 0.0391 0.2216
Brugia malayi Protein kinase domain containing protein 0.0708 0.0613 0.0609
Trichomonas vaginalis ribosomal protein S6 kinase, 90kD, polypeptide, putative 0.0323 0.0028 0.0109
Echinococcus multilocularis tyrosine protein kinase transmembrane receptor 0.0442 0.0209 0.0245
Echinococcus multilocularis sodium:potassium dependent atpase beta subunit 0.0739 0.0659 0.0849
Echinococcus multilocularis serine:threonine protein kinase 0.0676 0.0563 0.0721
Trypanosoma brucei kinetoplastid kinetochore protein 19 0.0666 0.0548 0.2113
Loa Loa (eye worm) RasGEF domain-containing protein 0.0322 0.0027 0.0027
Schistosoma mansoni growth factor receptor-bound protein 0.045 0.022 0.0411
Toxoplasma gondii NIMA-related protein kinase NIMA1 0.0812 0.0771 0.3566
Giardia lamblia Aurora kinase 0.1275 0.1472 0.831
Trichomonas vaginalis CAMK family protein kinase 0.1457 0.1749 0.8017
Loa Loa (eye worm) STE/STE20/PAKA protein kinase 0.0307 0.0004 0.0004
Echinococcus multilocularis calcium activated potassium channel 0.0718 0.0628 0.0807
Echinococcus multilocularis roundabout 2 0.0396 0.0139 0.0151
Echinococcus multilocularis MAP kinase activated protein kinase 2 0.2412 0.3198 0.4261
Trypanosoma cruzi kinetoplastid kinetochore protein 19, putative 0.0666 0.0548 0.3118
Trichomonas vaginalis STE family protein kinase 0.0501 0.0299 0.1356
Trypanosoma brucei rac serine-threonine kinase, putative 0.1742 0.2181 1
Schistosoma mansoni serine/threonine protein kinase 0.0545 0.0365 0.0685
Echinococcus granulosus titin 0.0395 0.0137 0.0122
Schistosoma mansoni serine/threonine protein kinase 0.0407 0.0156 0.0289
Echinococcus multilocularis cAMP dependent protein kinase catalytic subunit 0.0545 0.0365 0.0454
Entamoeba histolytica protein kinase, putative 0.1742 0.2181 1
Schistosoma mansoni nephrin 0.0898 0.0901 0.1702
Schistosoma mansoni tyrosine kinase 0.1179 0.1328 0.2513
Brugia malayi Protein kinase c protein 2 0.0748 0.0673 0.067
Brugia malayi Protein kinase domain containing protein 0.1013 0.1076 0.1072
Entamoeba histolytica PH domain containing protein kinase, putative 0.059 0.0433 0.1885
Echinococcus granulosus Protein kinase C brain isozyme 0.1534 0.1865 0.2027
Trichomonas vaginalis AGC family protein kinase 0.0323 0.0028 0.0109
Schistosoma mansoni septate junction protein 0.0341 0.0055 0.0097
Echinococcus granulosus serine:threonine protein kinase 3 0.156 0.1906 0.2072
Brugia malayi Protein kinase domain containing protein 0.2368 0.3132 0.313
Loa Loa (eye worm) hypothetical protein 0.0676 0.0563 0.0563
Trichomonas vaginalis CAMK family protein kinase 0.0451 0.0222 0.1003
Loa Loa (eye worm) CMGC/CDK/CDC2 protein kinase 0.0705 0.0607 0.0607
Loa Loa (eye worm) CAMK/CAMKL/BRSK protein kinase 0.0451 0.0222 0.0222
Echinococcus granulosus hypothetical protein 0.0493 0.0286 0.0286
Echinococcus multilocularis cyclin dependent kinase 0.0705 0.0607 0.078
Toxoplasma gondii CMGC kinase, CK2 family 0.0589 0.0432 0.1941
Loa Loa (eye worm) hypothetical protein 0.1885 0.2399 0.2399
Echinococcus granulosus cAMP dependent protein kinase catalytic subunit 0.0545 0.0365 0.0373
Echinococcus granulosus tyrosine protein kinase ABL1 0.1821 0.2302 0.2509
Schistosoma mansoni serine/threonine protein kinase 0.0718 0.0628 0.1184
Loa Loa (eye worm) hypothetical protein 0.089 0.0889 0.0889
Entamoeba histolytica serine/threonine protein kinase STE20, putative 0.0493 0.0286 0.1205
Schistosoma mansoni nephrin 0.0396 0.0139 0.0257
Echinococcus multilocularis protein kinase c epsilon type 0.1288 0.1492 0.1969
Loa Loa (eye worm) TK/FER protein kinase 0.0536 0.0351 0.0351
Loa Loa (eye worm) CMGC/CK2 protein kinase 0.0589 0.0432 0.0432
Echinococcus granulosus tyrosine protein kinase Src42A 0.072 0.063 0.0665
Trichomonas vaginalis STE family protein kinase 0.0367 0.0095 0.0418

Activities

Activity type Activity value Assay description Source Reference
Activity (functional) 0 Antagonist activity at dopamine D4.2 receptor assessed as inhibition of dopamine-induced effect at 5 uM ChEMBL. 17251022
Inhibition (binding) = 0 % Displacement of [3H]spiperone from human cloned dopamine D2L receptor at 1 uM ChEMBL. 17251022
Inhibition (binding) = 0 % Displacement of [3H]spiperone from human cloned dopamine D2L receptor at 1 uM ChEMBL. 17251022
Inhibition (binding) = 49 % Displacement of [3H]ketanserin from rat 5HT2A receptor at 1 uM ChEMBL. 17251022
Inhibition (binding) = 49 % Displacement of [3H]ketanserin from rat 5HT2A receptor at 1 uM ChEMBL. 17251022
Ki (binding) = 116 nM Displacement of [3H]nemonapride from human cloned dopamine D4.2 receptor ChEMBL. 17251022
Ki (binding) = 116 nM Displacement of [3H]nemonapride from human cloned dopamine D4.2 receptor ChEMBL. 17251022

Phenotypes

Whole-cell/tissue/organism interactions

We have no records of whole-cell/tissue assays done with this compound What does this mean?

Many chemical entities in TDR Targets come from high-throughput screenings with whole cells or tissue samples, and not all assayed compounds have been tested against a single a single target protein, probably because they get ruled out during screening process. Even if these compounds may have not been of interest in the original screening, they may come as interesting leads for other screening assays. Furthermore, we may be able to propose drug-target associations using chemical similarities and network patterns.

Annotated phenotypes:

We have no manually annotated phenotypes for this drug. What does this mean? / Care to help?
In TDR Targets, information about phenotypes that are caused by drugs, or by genetic manipulation of cells (e.g. gene knockouts or knockdowns) is manually curated from the literature. These descriptions help to describe the potential of the target for drug development. If no information is available for this gene or if the information is incomplete, this may mean that i) the papers containing this information either appeared after the curation effort for this organism was carried out or they were inadvertently missed by curators; or that ii) the curation effort for this organism has not yet started.
 
In any case, if you have information about papers containing relevant validation data for this target, please log in using your TDR Targets username and password and send them to us using the corresponding form in this page (only visible to registered users) or contact us.

External resources for this compound

Bibliographic References

1 literature reference was collected for this gene.

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