Detailed information for compound 546282

Basic information

Technical information
  • TDR Targets ID: 546282
  • Name: 3,4-dichloro-N-[2-(methylamino)cyclohexyl]ben zamide
  • MW: 301.212 | Formula: C14H18Cl2N2O
  • H donors: 2 H acceptors: 1 LogP: 3.36 Rotable bonds: 4
    Rule of 5 violations (Lipinski): 1
  • SMILES: CNC1CCCCC1NC(=O)c1ccc(c(c1)Cl)Cl
  • InChi: 1S/C14H18Cl2N2O/c1-17-12-4-2-3-5-13(12)18-14(19)9-6-7-10(15)11(16)8-9/h6-8,12-13,17H,2-5H2,1H3,(H,18,19)
  • InChiKey: DXQXUBODPOIWLJ-UHFFFAOYSA-N  


Substructure search Similarity search

Network

Hover on a compound node to display the structore

Synonyms

  • N-(2-methylaminocyclohexyl)-3,4-dichlorobenzamide
  • 3,4-dichloro-N-(2-methylaminocyclohexyl)benzamide
  • 147934-29-0
  • U 83894A
  • U-83894A
  • Benzamide, 3,4-dichloro-N-(2-(methylamino)cyclohexyl)-, monohydrochloride, cis-

Targets

Known targets for this compound

No curated genes were found associated with this compound

Predicted pathogen targets for this compound

By orthology
No druggable targets predicted by orthology data
By sequence similarity to non orthologous known druggable targets
No druggable targets predicted by sequence similarity
Obtained from network model

Ranking Plot

Putative Targets List

Species Potential target Raw Global Species
Brugia malayi beta-lactamase family protein 0.0215 0.0276 0.0274
Trypanosoma brucei glycerol uptake protein, putative 0.0383 0.0518 0.2115
Onchocerca volvulus 0.0178 0.0224 0.1661
Trypanosoma cruzi hypothetical protein, conserved 0.0215 0.0276 0.1138
Echinococcus granulosus rhodopsin orphan GPCR 0.0178 0.0224 0.0353
Mycobacterium ulcerans cytochrome P450 150A6 Cyp150A6 0.004 0.0025 0.0109
Loa Loa (eye worm) hypothetical protein 0.0178 0.0224 0.0222
Echinococcus granulosus zinc finger protein 0.4066 0.5804 0.9134
Loa Loa (eye worm) hypothetical protein 0.0024 0.0003 0.0001
Echinococcus multilocularis g protein linked acetylcholine receptor gar 2a 0.0178 0.0224 0.0353
Loa Loa (eye worm) hypothetical protein 0.0028 0.0008 0.0006
Echinococcus granulosus mitogen activated protein kinase 14 0.1709 0.242 0.3809
Mycobacterium tuberculosis Probable cytochrome P450 137 Cyp137 0.004 0.0025 0.0055
Echinococcus multilocularis integrin beta 2 0.0992 0.1392 0.2191
Schistosoma mansoni alpha-1 adrenergic receptor 0.0178 0.0224 0.0353
Loa Loa (eye worm) hypothetical protein 0.699 1 1
Trichomonas vaginalis calcium/calmodulin-dependent 3,5-cyclic nucleotide phosphodiesterase, putative 0.0026 0.0006 0.0039
Mycobacterium tuberculosis Probable cytochrome P450 128 Cyp128 0.004 0.0025 0.0055
Loa Loa (eye worm) hypothetical protein 0.0178 0.0224 0.0222
Echinococcus multilocularis tachykinin peptides receptor 99D 0.0178 0.0224 0.0353
Loa Loa (eye worm) hypothetical protein 0.0383 0.0518 0.0516
Loa Loa (eye worm) acetyltransferase 0.0153 0.0188 0.0185
Mycobacterium tuberculosis Probable cytochrome P450 124 Cyp124 0.004 0.0025 0.0055
Mycobacterium ulcerans beta-lactamase 0.0215 0.0276 0.5424
Trichomonas vaginalis conserved hypothetical protein 0.0026 0.0006 0.0038
Schistosoma mansoni nuclear hormone receptor superfamily protein-related 0.0024 0.0003 0.0004
Loa Loa (eye worm) hypothetical protein 0.0024 0.0003 0.0001
Mycobacterium tuberculosis Probable L-lysine-epsilon aminotransferase Lat (L-lysine aminotransferase) (lysine 6-aminotransferase) 0.0044 0.0031 0.0085
Loa Loa (eye worm) hypothetical protein 0.0052 0.0042 0.004
Trypanosoma brucei PAB1-binding protein , putative 0.005 0.0039 0.0129
Trichomonas vaginalis glutaminase, putative 0.0266 0.035 0.2613
Echinococcus granulosus FTZ F1 alpha 0.0051 0.0041 0.0065
Loa Loa (eye worm) hypothetical protein 0.0178 0.0224 0.0222
Echinococcus granulosus microtubule associated protein 2 0.2046 0.2905 0.4572
Loa Loa (eye worm) hypothetical protein 0.0052 0.0042 0.004
Echinococcus multilocularis rhodopsin orphan GPCR 0.0178 0.0224 0.0353
Trypanosoma cruzi DNA polymerase beta thumb, putative 0.0042 0.0028 0.0112
Mycobacterium ulcerans cytochrome P450 142A3 Cyp142A3 0.004 0.0025 0.0109
Brugia malayi Cytochrome P450 family protein 0.0156 0.0192 0.0189
Brugia malayi nicotinic acetylcholine receptor alpha subunit, putative 0.0052 0.0042 0.004
Mycobacterium tuberculosis Possible cytochrome P450 135A1 Cyp135A1 0.004 0.0025 0.0055
Echinococcus multilocularis g protein linked acetylcholine receptor gar 2a 0.0178 0.0224 0.0353
Echinococcus multilocularis glycine receptor subunit alpha 1 0.0052 0.0042 0.0067
Trichomonas vaginalis transmembrane protein nessy, putative 0.0383 0.0518 0.3872
Schistosoma mansoni nuclear hormone receptor 0.0024 0.0003 0.0004
Echinococcus multilocularis gcn5proteinral control of amino acid synthesis 0.0153 0.0188 0.0295
Trichomonas vaginalis cGMP-inhibited 3,5-cyclic phosphodiesterase, putative 0.006 0.0054 0.0396
Trichomonas vaginalis high-affinity cGMP-specific 3,5-cyclic phosphodiesterase, putative 0.006 0.0054 0.0396
Echinococcus granulosus intermediate filament protein 0.0052 0.0043 0.0068
Trichomonas vaginalis conserved hypothetical protein 0.0052 0.0043 0.0318
Schistosoma mansoni nAChR subunit 0.0052 0.0042 0.0067
Echinococcus granulosus neuropeptide Y receptor 0.0178 0.0224 0.0353
Loa Loa (eye worm) hypothetical protein 0.0028 0.0008 0.0006
Trichomonas vaginalis D-aminoacylase, putative 0.0215 0.0276 0.206
Loa Loa (eye worm) intermediate filament protein 0.0052 0.0043 0.0041
Trypanosoma brucei protein kinase, putative 0.011 0.0126 0.0488
Onchocerca volvulus 0.0178 0.0224 0.1661
Loa Loa (eye worm) hypothetical protein 0.0043 0.003 0.0028
Giardia lamblia Histone acetyltransferase GCN5 0.0041 0.0027 0.0256
Brugia malayi AKH receptor 0.0178 0.0224 0.0222
Trichomonas vaginalis helicase, putative 0.0026 0.0006 0.0038
Onchocerca volvulus Putative nachr subunit 0.0052 0.0042 0.0299
Schistosoma mansoni histone-lysine n-methyltransferase setb1 0.0122 0.0144 0.0226
Brugia malayi Latrophilin receptor protein 2 0.0031 0.0012 0.001
Echinococcus multilocularis dro:myosuppressin receptor 0.0178 0.0224 0.0353
Schistosoma mansoni biogenic amine (5HT) receptor 0.0178 0.0224 0.0353
Echinococcus granulosus geminin 0.0164 0.0204 0.0321
Loa Loa (eye worm) hypothetical protein 0.1184 0.1667 0.1666
Leishmania major cytochrome p450-like protein 0.004 0.0025 0.01
Onchocerca volvulus Neuropeptide F receptor homolog 0.0178 0.0224 0.1661
Schistosoma mansoni peptide (FMRFamide/neurokinin-3)-like receptor 0.0178 0.0224 0.0353
Echinococcus multilocularis FTZ F1 alpha 0.0051 0.0041 0.0065
Loa Loa (eye worm) hypothetical protein 0.0178 0.0224 0.0222
Schistosoma mansoni nuclear receptor nhr-48 0.0024 0.0003 0.0004
Giardia lamblia Tenascin precursor 0.0043 0.003 0.0429
Mycobacterium tuberculosis Dihydrolipoamide dehydrogenase LpdC (lipoamide reductase (NADH)) (lipoyl dehydrogenase) (dihydrolipoyl dehydrogenase) (diaphoras 0.0116 0.0135 0.0628
Echinococcus multilocularis cytoplasmic intermediate filament protein 0.0025 0.0004 0.0007
Echinococcus multilocularis neuropeptide FF receptor 2 0.0178 0.0224 0.0353
Trichomonas vaginalis chromodomain helicase DNA binding protein, putative 0.0026 0.0006 0.0038
Schistosoma mansoni serine/threonine protein kinase 0.011 0.0126 0.0198
Loa Loa (eye worm) hypothetical protein 0.0178 0.0224 0.0222
Schistosoma mansoni RAR-like nuclear receptor 0.0051 0.0041 0.0065
Echinococcus multilocularis orexin receptor type 2 0.0178 0.0224 0.0353
Trichomonas vaginalis conserved hypothetical protein 0.0052 0.0043 0.0318
Mycobacterium tuberculosis Probable NADH dehydrogenase Ndh 0.0105 0.0118 0.0541
Onchocerca volvulus 0.0043 0.003 0.0208
Trichomonas vaginalis ap endonuclease, putative 0.0038 0.0023 0.0168
Brugia malayi hypothetical protein 0.005 0.0039 0.0037
Echinococcus granulosus somatostatin receptor 0.0178 0.0224 0.0353
Echinococcus granulosus adam 0.0043 0.003 0.0047
Trichomonas vaginalis inositol monophosphatase, putative 0.0036 0.002 0.0143
Toxoplasma gondii CMGC kinase, MAPK family (ERK) MAPK-1 0.011 0.0126 0.2305
Trypanosoma brucei mitochondrial DNA polymerase beta-PAK 0.014 0.0169 0.0666
Echinococcus granulosus rhodopsin orphan GPCR 0.0178 0.0224 0.0353
Trypanosoma cruzi GUP1, putative 0.0383 0.0518 0.214
Echinococcus multilocularis ubiquitin carboxyl terminal hydrolase 8 0.0151 0.0185 0.029
Echinococcus granulosus rhodopsin orphan GPCR 0.0178 0.0224 0.0353
Mycobacterium tuberculosis Possible penicillin-binding protein 0.1371 0.1936 1
Schistosoma mansoni hypothetical protein 0.0178 0.0224 0.0353
Trypanosoma cruzi cAMP specific phosphodiesterase, putative 0.006 0.0054 0.0219
Loa Loa (eye worm) hypothetical protein 0.0052 0.0042 0.004
Loa Loa (eye worm) hypothetical protein 0.0178 0.0224 0.0222
Schistosoma mansoni amine GPCR 0.0178 0.0224 0.0353
Schistosoma mansoni mixed-lineage leukemia protein mll 0.025 0.0327 0.0515
Toxoplasma gondii acyl-CoA:cholesterol acyltransferase alpha ACAT1-alpha 0.0383 0.0518 1
Trypanosoma cruzi glycerol uptake protein, putative 0.0383 0.0518 0.214
Schistosoma mansoni loxhd1 0.0041 0.0027 0.0042
Loa Loa (eye worm) nuclear hormone receptor family member nhr-40 0.0051 0.0041 0.0039
Trypanosoma brucei cAMP-specific phosphodiesterase 0.006 0.0054 0.0188
Schistosoma mansoni thyroid hormone receptor 0.0051 0.0041 0.0065
Echinococcus granulosus rhodopsin orphan GPCR 0.0178 0.0224 0.0353
Echinococcus granulosus nicotinic acetylcholine receptor subunit type 0.0052 0.0042 0.0067
Echinococcus granulosus 5'partial|histone lysine N methyltransferase SETDB2 0.0116 0.0134 0.0211
Trichomonas vaginalis CMGC family protein kinase 0.011 0.0126 0.0936
Trichomonas vaginalis cone cGMP-specific 3,5-cyclic phosphodiesterase, putative 0.006 0.0054 0.0396
Loa Loa (eye worm) pre-SET domain-containing protein family protein 0.0839 0.1172 0.117
Trypanosoma cruzi mitochondrial DNA polymerase beta-PAK, putative 0.014 0.0169 0.0696
Mycobacterium tuberculosis Probable lipase LipE 0.0215 0.0276 0.1362
Echinococcus multilocularis neuropeptide Y receptor 0.0178 0.0224 0.0353
Echinococcus multilocularis nicotinic acetylcholine receptor alpha subunit 0.0052 0.0042 0.0067
Echinococcus multilocularis fmrfamide receptor 0.0178 0.0224 0.0353
Trypanosoma cruzi DNA polymerase beta thumb, putative 0.0042 0.0028 0.0112
Brugia malayi exodeoxyribonuclease III family protein 0.0038 0.0023 0.0021
Loa Loa (eye worm) hypothetical protein 0.0383 0.0518 0.0516
Loa Loa (eye worm) hypothetical protein 0.0047 0.0035 0.0033
Schistosoma mansoni nAChR subunit 0.0052 0.0042 0.0067
Echinococcus multilocularis neuropeptide receptor 0.0178 0.0224 0.0353
Echinococcus multilocularis fibrillin 2 0.0043 0.003 0.0047
Trypanosoma cruzi Lanosterol 14-alpha demethylase 0.004 0.0025 0.01
Echinococcus multilocularis histone lysine N methyltransferase MLL3 0.0033 0.0016 0.0025
Mycobacterium tuberculosis Probable conserved lipoprotein 0.0215 0.0276 0.1362
Mycobacterium tuberculosis Probable cytochrome P450 143 Cyp143 0.004 0.0025 0.0055
Onchocerca volvulus 0.0052 0.0042 0.0299
Trichomonas vaginalis conserved hypothetical protein 0.0026 0.0006 0.0038
Brugia malayi Dopamine receptor protein 2 0.0178 0.0224 0.0222
Mycobacterium tuberculosis Probable ornithine aminotransferase (N-terminus part) RocD1 (ornithine--oxo-acid aminotransferase) 0.0044 0.0031 0.0085
Echinococcus multilocularis cadherin EGF LAG seven pass G type receptor 0.0031 0.0012 0.002
Loa Loa (eye worm) hypothetical protein 0.0052 0.0042 0.004
Brugia malayi MBOAT family protein 0.445 0.6354 0.6354
Brugia malayi Serotonin receptor 0.1173 0.1651 0.1649
Trichomonas vaginalis cAMP-specific phosphodiesterase, putative 0.006 0.0054 0.0396
Giardia lamblia Tenascin-like 0.0043 0.003 0.0429
Brugia malayi Nuclear hormone receptor family member nhr-49 0.0051 0.0041 0.0039
Schistosoma mansoni membrane-bound acyltransferase/hhat 0.0383 0.0518 0.0816
Schistosoma mansoni nAChR subunit 0.0024 0.0002 0.0004
Echinococcus granulosus acetylcholine receptor subunit beta 1 0.0052 0.0042 0.0067
Echinococcus granulosus sex peptide receptor 0.0178 0.0224 0.0353
Trichomonas vaginalis cyclic nucleotide phosphodiesterase, putative 0.006 0.0054 0.0396
Mycobacterium ulcerans cytochrome P450 125A7 Cyp125A7 0.004 0.0025 0.0109
Loa Loa (eye worm) hhat protein 0.0383 0.0518 0.0516
Echinococcus granulosus ubiquitin specific protease 41 0.0151 0.0185 0.029
Brugia malayi Dopamine receptor protein 1 0.0178 0.0224 0.0222
Echinococcus granulosus histone acetyltransferase KAT2B 0.0045 0.0033 0.0051
Schistosoma mansoni o-acyltransferase (membrane bound) domain containing protein 0.0383 0.0518 0.0816
Brugia malayi hypothetical protein 0.0204 0.026 0.0258
Brugia malayi Neurotransmitter-gated ion-channel transmembrane region family protein 0.0028 0.0008 0.0006
Schistosoma mansoni hypothetical protein 0.0322 0.043 0.0677
Echinococcus granulosus neuropeptide receptor 0.0178 0.0224 0.0353
Entamoeba histolytica ubiquitin carboxyl-terminal hydrolase domain containing protein 0.0151 0.0185 0.3551
Loa Loa (eye worm) nuclear hormone receptor family member nhr-31 0.0051 0.0041 0.0039
Brugia malayi Cytochrome P450 family protein 0.0058 0.0051 0.0049
Schistosoma mansoni histamine-responsive GPCR (AAF21638) 0.0178 0.0224 0.0353
Brugia malayi Hhat protein 0.0383 0.0518 0.0516
Toxoplasma gondii histone lysine methyltransferase SET1 0.0228 0.0295 0.5622
Brugia malayi larval opioid receptor 0.0178 0.0224 0.0222
Trichomonas vaginalis teneurin and N-acetylglucosamine-1-phosphodiester alpha-N-acetylglucosaminidase, putative 0.0043 0.003 0.022
Echinococcus granulosus GPCR family 2 0.0031 0.0012 0.002
Schistosoma mansoni hypothetical protein 0.0043 0.003 0.0047
Brugia malayi P38 map kinase family protein 2 0.1709 0.242 0.2419
Loa Loa (eye worm) hypothetical protein 0.0178 0.0224 0.0222
Onchocerca volvulus 0.0041 0.0027 0.0182
Echinococcus granulosus nicotinic acetylcholine receptor a11 subunit 0.0052 0.0042 0.0067
Mycobacterium ulcerans cytochrome P450 189A7 Cyp189A7 0.004 0.0025 0.0109
Loa Loa (eye worm) neuropeptide F receptor 0.0178 0.0224 0.0222
Echinococcus granulosus rhodopsin orphan GPCR 0.0178 0.0224 0.0353
Brugia malayi GTP-binding regulatory protein Gs alpha-S chain, putative 0.041 0.0557 0.0555
Schistosoma mansoni peptide (allatostatin/somatostatin)-like receptor 0.0178 0.0224 0.0353
Schistosoma mansoni peptide (FMRFamide/somatostatin)-like receptor 0.0178 0.0224 0.0353
Echinococcus multilocularis mitogen activated protein kinase 14 0.1709 0.242 0.3809
Brugia malayi hypothetical protein 0.0178 0.0224 0.0222
Brugia malayi Pre-SET motif family protein 0.0839 0.1172 0.117
Trypanosoma cruzi mitogen-activated protein kinase 3, putative 0.1709 0.242 1
Echinococcus multilocularis rhodopsin orphan GPCR 0.0178 0.0224 0.0353
Schistosoma mansoni nuclear receptor 2DBD-gamma 0.0051 0.0041 0.0065
Loa Loa (eye worm) hypothetical protein 0.0052 0.0042 0.004
Echinococcus multilocularis gamma aminobutyric acid receptor subunit 0.0024 0.0002 0.0004
Echinococcus granulosus nAChR subunit 0.0028 0.0008 0.0013
Brugia malayi nicotinic acetylcholine receptor beta-1 chain precursor 0.0052 0.0042 0.004
Echinococcus multilocularis nuclear receptor 2DBD gamma 0.0051 0.0041 0.0065
Brugia malayi MBOAT family protein 0.0383 0.0518 0.0516
Schistosoma mansoni neurotransmitter gated ion channel 0.0028 0.0008 0.0013
Loa Loa (eye worm) cytochrome P450 0.004 0.0025 0.0023
Onchocerca volvulus Nuclear receptor subfamily 6 group A member 1 homolog 0.0024 0.0003 0.0002
Brugia malayi Neurotransmitter-gated ion-channel ligand binding domain containing protein 0.0052 0.0042 0.004
Toxoplasma gondii hypothetical protein 0.0383 0.0518 1
Loa Loa (eye worm) kelch domain-containing protein family protein 0.0204 0.026 0.0258
Echinococcus multilocularis lamin dm0 0.0052 0.0043 0.0068
Schistosoma mansoni nuclear hormone receptor nor-1/nor-2 0.0051 0.0041 0.0065
Echinococcus granulosus fibrillin 1 0.0043 0.003 0.0047
Brugia malayi Dopamine receptor 0.0178 0.0224 0.0222
Schistosoma mansoni hypothetical protein 0.0031 0.0012 0.002
Echinococcus multilocularis retinoic acid receptor rxr beta a retinoic acid receptor rxr alpha a retinoic acid receptor rxr alpha 0.0024 0.0003 0.0004
Loa Loa (eye worm) doublecortin family protein 0.0041 0.0027 0.0024
Plasmodium vivax multidomain scavenger receptor, putative 0.0041 0.0027 0.036
Mycobacterium ulcerans fusion of enoyl-CoA hydratase, EchA21 and lipase, LipE 0.0215 0.0276 0.5424
Mycobacterium tuberculosis Probable cytochrome P450 136 Cyp136 0.004 0.0025 0.0055
Schistosoma mansoni histamine h1 receptor 0.0178 0.0224 0.0353
Trypanosoma brucei Lanosterol 14-alpha demethylase 0.004 0.0025 0.0069
Schistosoma mansoni hypothetical protein 0.0031 0.0012 0.002
Loa Loa (eye worm) hypothetical protein 0.0178 0.0224 0.0222
Onchocerca volvulus 0.0215 0.0276 0.205
Giardia lamblia hypothetical protein 0.0043 0.003 0.0429
Brugia malayi cytochrome P450 0.004 0.0025 0.0023
Giardia lamblia Tenascin-X 0.0043 0.003 0.0429
Trichomonas vaginalis conserved hypothetical protein 0.0026 0.0006 0.0038
Trichomonas vaginalis D-aminoacylase, putative 0.0215 0.0276 0.206
Echinococcus multilocularis thioredoxin glutathione reductase 0.0046 0.0034 0.0053
Trypanosoma cruzi mitogen-activated protein kinase 11, putative 0.011 0.0126 0.0517
Loa Loa (eye worm) hypothetical protein 0.0052 0.0042 0.004
Echinococcus multilocularis Polycystic kidney disease protein 0.0041 0.0027 0.0042
Schistosoma mansoni nuclear receptor 0.0024 0.0003 0.0004
Onchocerca volvulus 0.0052 0.0042 0.0299
Brugia malayi hypothetical protein 0.0178 0.0224 0.0222
Plasmodium vivax diacylglycerol O-acyltransferase, putative 0.0383 0.0518 1
Echinococcus multilocularis alpha 1A adrenergic receptor 0.0178 0.0224 0.0353
Loa Loa (eye worm) hypothetical protein 0.0383 0.0518 0.0516
Trypanosoma cruzi mitogen-activated protein kinase 3, putative 0.1709 0.242 1
Schistosoma mansoni family S12 unassigned peptidase (S12 family) 0.0215 0.0276 0.0435
Echinococcus multilocularis adam 0.0043 0.003 0.0047
Echinococcus multilocularis Aminotransferase class III 0.0044 0.0031 0.0048
Loa Loa (eye worm) hypothetical protein 0.0178 0.0224 0.0222
Echinococcus multilocularis allatostatin A receptor 0.0178 0.0224 0.0353
Echinococcus granulosus tm gpcr rhodopsin 0.0178 0.0224 0.0353
Onchocerca volvulus 0.0178 0.0224 0.1661
Loa Loa (eye worm) nicotinic acetylcholine receptor alpha subunit 0.0052 0.0042 0.004
Mycobacterium tuberculosis Conserved protein 0.0215 0.0276 0.1362
Trichomonas vaginalis cGMP-specific 3,5-cyclic phosphodiesterase, putative 0.006 0.0054 0.0396
Brugia malayi Calcitonin receptor-like protein seb-1 0.0098 0.0108 0.0106
Brugia malayi sulfakinin receptor protein 0.699 1 1
Schistosoma mansoni retinoic acid receptor RXR 0.0051 0.0041 0.0065
Trichomonas vaginalis conserved hypothetical protein 0.0151 0.0185 0.1375
Schistosoma mansoni intermediate filament proteins 0.0052 0.0043 0.0068
Loa Loa (eye worm) hypothetical protein 0.0043 0.003 0.0027
Mycobacterium ulcerans lipase LipD 0.0215 0.0276 0.5424
Loa Loa (eye worm) hypothetical protein 0.0178 0.0224 0.0222
Onchocerca volvulus 0.0215 0.0276 0.205
Onchocerca volvulus 0.0178 0.0224 0.1661
Loa Loa (eye worm) hypothetical protein 0.0178 0.0224 0.0222
Mycobacterium tuberculosis Probable exodeoxyribonuclease III protein XthA (exonuclease III) (EXO III) (AP endonuclease VI) 0.0038 0.0023 0.0045
Loa Loa (eye worm) pigment dispersing factor receptor c 0.0098 0.0108 0.0106
Echinococcus multilocularis dnaJ subfamily B 0.1244 0.1753 0.2759
Loa Loa (eye worm) hypothetical protein 0.0052 0.0042 0.004
Brugia malayi glutaminase DH11.1 0.0266 0.035 0.0348
Mycobacterium ulcerans aldehyde dehydrogenase 0.0365 0.0492 1
Brugia malayi MBOAT family protein 0.0383 0.0518 0.0516
Loa Loa (eye worm) hypothetical protein 0.0215 0.0276 0.0274
Trypanosoma cruzi PAB1-binding protein , putative 0.005 0.0039 0.016
Loa Loa (eye worm) GTP-binding regulatory protein Gs alpha-S chain 0.041 0.0557 0.0555
Echinococcus granulosus g protein linked acetylcholine receptor gar 2a 0.0178 0.0224 0.0353
Brugia malayi hypothetical protein 0.0178 0.0224 0.0222
Echinococcus granulosus mitogen activated protein kinase 0.011 0.0126 0.0198
Schistosoma mansoni lamin 0.0052 0.0043 0.0068
Echinococcus multilocularis mixed lineage leukemia protein mll 0.0033 0.0016 0.0025
Echinococcus multilocularis Nuclear hormone receptor HR96 0.0024 0.0003 0.0004
Loa Loa (eye worm) nuclear hormone receptor family member nhr-1 0.0051 0.0041 0.0039
Trichomonas vaginalis conserved hypothetical protein 0.0026 0.0006 0.0038
Loa Loa (eye worm) G-protein coupled receptor 0.0178 0.0224 0.0222
Schistosoma mansoni steroid hormone receptor ad4bp 0.0051 0.0041 0.0065
Brugia malayi MBOAT family protein 0.0383 0.0518 0.0516
Schistosoma mansoni polycystin 1-related 0.0041 0.0027 0.0042
Trypanosoma cruzi PAB1-binding protein , putative 0.005 0.0039 0.016
Brugia malayi hypothetical protein 0.0178 0.0224 0.0222
Trypanosoma cruzi cAMP specific phosphodiesterase, putative 0.0041 0.0026 0.0106
Echinococcus multilocularis mitogen activated protein kinase 0.011 0.0126 0.0198
Toxoplasma gondii ABC1 family protein 0.0215 0.0276 0.525
Echinococcus granulosus dro:myosuppressin receptor 0.0178 0.0224 0.0353
Schistosoma mansoni opsin-like receptor 0.0178 0.0224 0.0353
Schistosoma mansoni retinoid-x-receptor (RXR) 0.0027 0.0007 0.0011
Schistosoma mansoni adenoreceptor 0.0178 0.0224 0.0353
Brugia malayi Hypothetical glycine receptor like protein T20B12.9 in chromosome III 0.0052 0.0042 0.004
Brugia malayi 3'5'-cyclic nucleotide phosphodiesterase family protein 0.0026 0.0006 0.0004
Loa Loa (eye worm) hypothetical protein 0.0028 0.0008 0.0006
Echinococcus granulosus cytochrome P450 2K1 0.004 0.0025 0.0039
Onchocerca volvulus 0.0041 0.0027 0.0182
Brugia malayi Intermediate filament tail domain containing protein 0.0052 0.0043 0.0041
Schistosoma mansoni nuclear receptor 0.0024 0.0003 0.0004
Onchocerca volvulus 0.0052 0.0042 0.0299
Echinococcus granulosus histone lysine N methyltransferase MLL3 0.0033 0.0016 0.0025
Toxoplasma gondii histone lysine acetyltransferase GCN5-A 0.0045 0.0033 0.0478
Onchocerca volvulus 0.0178 0.0224 0.1661
Trichomonas vaginalis cGMP-dependent 3,5-cyclic phosphodiesterase, putative 0.0026 0.0006 0.0039
Echinococcus multilocularis rhodopsin orphan GPCR 0.0178 0.0224 0.0353
Schistosoma mansoni hypothetical protein 0.0178 0.0224 0.0353
Echinococcus granulosus mixed lineage leukemia protein mll 0.0033 0.0016 0.0025
Echinococcus multilocularis g-protein coupled receptor 0.0178 0.0224 0.0353
Giardia lamblia High cysteine protein 0.0043 0.003 0.0429
Plasmodium vivax ataxin-2 like protein, putative 0.005 0.0039 0.0608
Plasmodium falciparum AP endonuclease (DNA-[apurinic or apyrimidinic site] lyase), putative 0.0038 0.0023 0.0292
Mycobacterium tuberculosis Probable acetylornithine aminotransferase ArgD 0.0044 0.0031 0.0085
Schistosoma mansoni nAChR subunit (ShAR1-beta-like) 0.0052 0.0042 0.0067
Schistosoma mansoni survival motor neuron protein 0.0143 0.0174 0.0273
Echinococcus granulosus cAMP and cAMP inhibited cGMP 3'5' cyclic 0.0026 0.0006 0.0009
Echinococcus granulosus biogenic amine 5HT receptor 0.0178 0.0224 0.0353
Schistosoma mansoni ubiquitin-specific peptidase 2 (C19 family) 0.0151 0.0185 0.029
Plasmodium falciparum glutathione reductase 0.0046 0.0034 0.0504
Trichomonas vaginalis set domain proteins, putative 0.0954 0.1338 1
Brugia malayi Nuclear hormone receptor family member nhr-3 0.0051 0.0041 0.0039
Loa Loa (eye worm) hypothetical protein 0.0027 0.0007 0.0004
Echinococcus multilocularis integrin alpha ps 0.0043 0.003 0.0047
Echinococcus granulosus snurportin 1 0.0299 0.0397 0.0624
Echinococcus granulosus glycine receptor subunit alpha 1 0.0052 0.0042 0.0067
Loa Loa (eye worm) glutaminase 2 0.0266 0.035 0.0348
Trichomonas vaginalis CMGC family protein kinase 0.011 0.0126 0.0936
Echinococcus granulosus nuclear receptor 2DBD gamma 0.0051 0.0041 0.0065
Mycobacterium ulcerans cytochrome P450 187A4 Cyp187A4 0.004 0.0025 0.0109
Brugia malayi hypothetical protein 0.0041 0.0027 0.0024
Echinococcus multilocularis o acyltransferase (membrane bound) domain 0.0383 0.0518 0.0816
Schistosoma mansoni nicotinic acetylcholine receptor alpha 0.0028 0.0008 0.0013
Echinococcus multilocularis membrane bound acyltransferase:hhat 0.0383 0.0518 0.0816
Echinococcus granulosus gamma aminobutyric acid receptor subunit 0.0024 0.0002 0.0004
Schistosoma mansoni rab6-interacting 0.0041 0.0027 0.0042
Entamoeba histolytica hypothetical protein 0.0322 0.043 0.8301
Schistosoma mansoni Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) 0.041 0.0557 0.0876
Entamoeba histolytica hypothetical protein 0.0322 0.043 0.8301
Echinococcus multilocularis cAMP and cAMP inhibited cGMP 3',5' cyclic 0.0026 0.0006 0.0009
Onchocerca volvulus 0.0178 0.0224 0.1661
Loa Loa (eye worm) hypothetical protein 0.0043 0.003 0.0027
Echinococcus multilocularis nicotinic acetylcholine receptor a11 subunit 0.0052 0.0042 0.0067
Schistosoma mansoni hypothetical protein 0.004 0.0025 0.0039
Brugia malayi Iron-sulfur cluster assembly accessory protein 0.0143 0.0174 0.0172
Trichomonas vaginalis calcium/calmodulin-dependent 3,5-cyclic nucleotide phosphodiesterase, putative 0.006 0.0054 0.0396
Mycobacterium tuberculosis Probable nitrite reductase [NAD(P)H] large subunit [FAD flavoprotein] NirB 0.0105 0.0118 0.0541
Loa Loa (eye worm) hypothetical protein 0.0027 0.0007 0.0004
Echinococcus granulosus serotonin receptor 0.0178 0.0224 0.0353
Trichomonas vaginalis hypothetical protein 0.0043 0.003 0.022
Schistosoma mansoni lipoxygenase 0.018 0.0227 0.0357
Loa Loa (eye worm) hypothetical protein 0.0051 0.0041 0.0039
Brugia malayi Kelch motif family protein 0.0204 0.026 0.0258
Loa Loa (eye worm) G-protein-linked acetylcholine receptor protein 2 0.0178 0.0224 0.0222
Mycobacterium tuberculosis Probable membrane NADH dehydrogenase NdhA 0.0105 0.0118 0.0541
Loa Loa (eye worm) glutamate-gated chloride channel alpha3A subunit 0.0052 0.0042 0.004
Mycobacterium tuberculosis Possible cytochrome P450 126 Cyp126 0.004 0.0025 0.0055
Schistosoma mansoni biogenic amine (dopamine) receptor 0.0178 0.0224 0.0353
Echinococcus multilocularis mitogen activated protein kinase 11 0.1709 0.242 0.3809
Entamoeba histolytica hypothetical protein 0.0028 0.0008 0.0143
Trypanosoma cruzi ubiquitin carboxyl-terminal hydrolase, putative 0.0151 0.0185 0.076
Echinococcus multilocularis musashi 0.0052 0.0043 0.0068
Echinococcus granulosus glycine receptor subunit alpha 1 0.0052 0.0042 0.0067
Brugia malayi hypothetical protein 0.0027 0.0007 0.0004
Brugia malayi Pre-SET motif family protein 0.0122 0.0144 0.0142
Loa Loa (eye worm) gonadotropin-releasing hormone receptor 2 0.0178 0.0224 0.0222
Echinococcus multilocularis nicotinic acetylcholine receptor beta 1 subunit 0.0052 0.0042 0.0067
Trypanosoma cruzi cytochrome P450, putative 0.0058 0.0051 0.0208
Entamoeba histolytica exodeoxyribonuclease III, putative 0.0038 0.0023 0.0434
Echinococcus multilocularis acetylcholine receptor subunit beta 1 0.0052 0.0042 0.0067
Schistosoma mansoni hypothetical protein 0.0299 0.0397 0.0624
Echinococcus multilocularis G-protein coupled receptor, putative 0.0178 0.0224 0.0353
Mycobacterium tuberculosis Conserved protein 0.0215 0.0276 0.1362
Echinococcus granulosus integrin alpha 3 0.0043 0.003 0.0047
Echinococcus granulosus neuropeptide Y receptor 0.0178 0.0224 0.0353
Toxoplasma gondii inositol(myo)-1(or 4)-monophosphatase 2, putative 0.0036 0.002 0.0227
Loa Loa (eye worm) nuclear Hormone Receptor family member 0.0051 0.0041 0.0039
Mycobacterium leprae conserved hypothetical protein 0.0215 0.0276 0.6639
Schistosoma mansoni inositol monophosphatase 0.0036 0.002 0.0031
Mycobacterium ulcerans cytochrome P450 143A3 Cyp143A3 0.004 0.0025 0.0109
Loa Loa (eye worm) hypothetical protein 0.0052 0.0042 0.004
Schistosoma mansoni nAChR subunit 0.0052 0.0042 0.0067
Brugia malayi EGF-like domain containing protein 0.0043 0.003 0.0028
Brugia malayi cytoplasmic intermediate filament protein 0.0028 0.0008 0.0006
Trypanosoma cruzi apurinic/apyrimidinic endonuclease 0.0038 0.0023 0.0093
Echinococcus multilocularis diacylglycerol O acyltransferase 1 0.0383 0.0518 0.0816
Loa Loa (eye worm) hypothetical protein 0.0052 0.0042 0.004
Loa Loa (eye worm) unidentified vitellogenin-linked transcript protein 6 0.0178 0.0224 0.0222
Echinococcus multilocularis neuropeptide s receptor 0.0657 0.0911 0.1434
Trichomonas vaginalis cAMP-specific phosphodiesterase, putative 0.006 0.0054 0.0396
Mycobacterium tuberculosis Probable lipase LipD 0.0215 0.0276 0.1362
Trichomonas vaginalis cone cGMP-specific 3,5-cyclic phosphodiesterase, putative 0.006 0.0054 0.0396
Echinococcus multilocularis integrin alpha 3 0.0043 0.003 0.0047
Loa Loa (eye worm) histone methyltransferase 0.004 0.0026 0.0024
Echinococcus granulosus fibrillin 2 0.0043 0.003 0.0047
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0178 0.0224 0.0353
Plasmodium falciparum LCCL domain-containing protein 0.0041 0.0027 0.036
Echinococcus granulosus G protein coupled receptor 139 0.0178 0.0224 0.0353
Echinococcus granulosus neuropeptides capa receptor 0.0178 0.0224 0.0353
Echinococcus multilocularis geminin 0.0164 0.0204 0.0321
Schistosoma mansoni histone-lysine n-methyltransferase setb1 0.0122 0.0144 0.0226
Loa Loa (eye worm) hypothetical protein 0.0178 0.0224 0.0222
Brugia malayi RE15519p 0.0178 0.0224 0.0222
Wolbachia endosymbiont of Brugia malayi acetylornithine transaminase protein 0.0044 0.0031 1
Loa Loa (eye worm) CMGC/MAPK/ERK1 protein kinase 0.011 0.0126 0.0124
Loa Loa (eye worm) nuclear hormone receptor family member nhr-14 0.0051 0.0041 0.0039
Schistosoma mansoni ap endonuclease 0.0038 0.0023 0.0036
Trypanosoma brucei mitogen-activated protein kinase 3, putative 0.1709 0.242 1
Echinococcus multilocularis mitogen activated protein kinase 11 0.1709 0.242 0.3809
Trypanosoma brucei hypothetical protein, conserved 0.0215 0.0276 0.1111
Entamoeba histolytica membrane-bound O-acyltransferase (MBOAT ) family protein 0.0383 0.0518 1
Echinococcus multilocularis o acyltransferase (membrane bound) domain 0.0383 0.0518 0.0816
Plasmodium falciparum diacylglycerol O-acyltransferase 0.0383 0.0518 1
Schistosoma mansoni hypothetical protein 0.1244 0.1753 0.2759
Loa Loa (eye worm) G-protein coupled receptor 0.0178 0.0224 0.0222
Brugia malayi ecdysteroid receptor 0.0051 0.0041 0.0039
Loa Loa (eye worm) hypothetical protein 0.0215 0.0276 0.0274
Leishmania major cytochrome p450-like protein 0.0058 0.0051 0.0208
Schistosoma mansoni coup transcription factor 0.0051 0.0041 0.0065
Trichomonas vaginalis myo inositol monophosphatase, putative 0.0036 0.002 0.0143
Echinococcus multilocularis g protein coupled receptor 0.0178 0.0224 0.0353
Loa Loa (eye worm) CMGC/MAPK/P38 protein kinase 0.1709 0.242 0.2419
Mycobacterium tuberculosis Probable cytochrome P450 130 Cyp130 0.004 0.0025 0.0055
Schistosoma mansoni hypothetical protein 0.0383 0.0518 0.0816
Brugia malayi Tachykinin-like peptides receptor 99D 0.0178 0.0224 0.0222
Loa Loa (eye worm) hypothetical protein 0.0178 0.0224 0.0222
Entamoeba histolytica hypothetical protein 0.0322 0.043 0.8301
Leishmania major ubiquitin hydrolase, putative,cysteine peptidase, Clan CA, family C19, putative 0.0151 0.0185 0.076
Trypanosoma cruzi mitogen activated protein kinase 2, putative 0.011 0.0126 0.0517
Entamoeba histolytica membrane-bound O-acyltransferase (MBOAT ) family protein 0.0383 0.0518 1
Trichomonas vaginalis cyclic nucleotide phosphodiesterase, putative 0.006 0.0054 0.0396
Schistosoma mansoni biogenic amine (dopamine) receptor 0.0178 0.0224 0.0353
Echinococcus granulosus cytoplasmic intermediate filament protein 0.0025 0.0004 0.0007
Brugia malayi Nuclear hormone receptor-like 1 0.0027 0.0007 0.0004
Brugia malayi glutathione reductase 0.0046 0.0034 0.0032
Brugia malayi hypothetical protein 0.0126 0.0149 0.0146
Echinococcus granulosus biogenic amine 5HT receptor 0.0178 0.0224 0.0353
Toxoplasma gondii hypothetical protein 0.0043 0.003 0.0427
Echinococcus granulosus Cys loop ligand gated ion channel subunit 0.0052 0.0042 0.0067
Echinococcus multilocularis tm gpcr rhodopsin gpcr rhodopsin superfamily 0.0178 0.0224 0.0353
Brugia malayi hypothetical protein 0.0322 0.043 0.0428
Echinococcus granulosus muscleblind protein 0.1184 0.1667 0.2624
Trichomonas vaginalis chromodomain helicase DNA binding protein, putative 0.0026 0.0006 0.0038
Echinococcus multilocularis integrin alpha ps 0.0089 0.0097 0.0152
Brugia malayi Nuclear hormone receptor family member nhr-19 0.0051 0.0041 0.0039
Mycobacterium ulcerans acetylornithine aminotransferase 0.0044 0.0031 0.0231
Onchocerca volvulus 0.0052 0.0043 0.0306
Loa Loa (eye worm) hypothetical protein 0.0178 0.0224 0.0222
Mycobacterium tuberculosis Probable hydrolase 0.0215 0.0276 0.1362
Mycobacterium leprae Probable lipase LipE 0.0215 0.0276 0.6639
Brugia malayi F/Y-rich N-terminus family protein 0.004 0.0025 0.0023
Echinococcus granulosus lysophospholipid acyltransferase 7 0.0383 0.0518 0.0816
Schistosoma mansoni amine GPCR 0.0178 0.0224 0.0353
Echinococcus multilocularis zinc finger protein 0.4066 0.5804 0.9134
Echinococcus granulosus histone lysine methyltransferase setb 0.0122 0.0144 0.0226
Schistosoma mansoni hypothetical protein 0.0178 0.0224 0.0353
Echinococcus multilocularis thyrotropin releasing hormone receptor 0.0178 0.0224 0.0353
Schistosoma mansoni leukocyte receptor cluster (lrc) member 4 protein 0.0383 0.0518 0.0816
Trypanosoma cruzi glycerol uptake protein, putative 0.0383 0.0518 0.214
Loa Loa (eye worm) hypothetical protein 0.0178 0.0224 0.0222
Toxoplasma gondii cytochrome p450 superfamily protein 0.004 0.0025 0.0328
Mycobacterium tuberculosis Probable cytochrome P450 138 Cyp138 0.004 0.0025 0.0055
Echinococcus multilocularis rhodopsin orphan GPCR 0.0178 0.0224 0.0353
Echinococcus granulosus g protein coupled receptor 0.0178 0.0224 0.0353
Echinococcus granulosus lamin 0.0052 0.0043 0.0068
Loa Loa (eye worm) hypothetical protein 0.0178 0.0224 0.0222
Loa Loa (eye worm) hypothetical protein 0.0178 0.0224 0.0222
Trypanosoma cruzi GUP1, putative 0.0383 0.0518 0.214
Trichomonas vaginalis cGMP-specific 3,5-cyclic phosphodiesterase, putative 0.006 0.0054 0.0396
Echinococcus multilocularis o acyltransferase (membrane bound) domain 0.0383 0.0518 0.0816
Mycobacterium tuberculosis Probable cytochrome P450 144 Cyp144 0.004 0.0025 0.0055
Brugia malayi Nuclear hormone receptor family member nhr-25 0.0051 0.0041 0.0039
Schistosoma mansoni opsin-like receptor 0.0178 0.0224 0.0353
Echinococcus multilocularis neuropeptide Y receptor 0.0178 0.0224 0.0353
Echinococcus multilocularis thyroid hormone receptor alpha 0.0051 0.0041 0.0065
Schistosoma mansoni sterol O-acyltransferase 1 0.0383 0.0518 0.0816
Plasmodium vivax glutathione reductase, putative 0.0046 0.0034 0.0504
Trypanosoma brucei DNA polymerase beta thumb, putative 0.0042 0.0028 0.0081
Trichomonas vaginalis chromodomain helicase DNA binding protein, putative 0.0026 0.0006 0.0038
Schistosoma mansoni zinc finger protein 0.445 0.6354 1
Echinococcus granulosus histone lysine N methyltransferase MLL3 0.004 0.0026 0.0041
Loa Loa (eye worm) hypothetical protein 0.0215 0.0276 0.0274
Mycobacterium ulcerans cytochrome P450 108B4 Cyp108B4 0.004 0.0025 0.0109
Loa Loa (eye worm) hypothetical protein 0.0043 0.003 0.0028
Brugia malayi Inositol-1 0.0036 0.002 0.0017
Echinococcus multilocularis inositol monophosphatase 1 0.0036 0.002 0.0031
Brugia malayi MAP kinase sur-1 0.011 0.0126 0.0124
Echinococcus multilocularis Cys loop ligand gated ion channel subunit 0.0024 0.0002 0.0004
Loa Loa (eye worm) hypothetical protein 0.0178 0.0224 0.0222
Echinococcus multilocularis protein cysteine N palmitoyltransferase 0.445 0.6354 1
Schistosoma mansoni hypothetical protein 0.0031 0.0012 0.002
Trypanosoma brucei apurinic/apyrimidinic endonuclease, putative 0.0038 0.0023 0.0062
Schistosoma mansoni nuclear hormone receptor 0.0024 0.0003 0.0004
Loa Loa (eye worm) hypothetical protein 0.0052 0.0043 0.0041
Brugia malayi Thioredoxin reductase 0.0046 0.0034 0.0032
Echinococcus multilocularis nuclear receptor 2DBD gamma 0.0051 0.0041 0.0065
Brugia malayi photoreceptor-specific nuclear receptor 0.0051 0.0041 0.0039
Echinococcus granulosus nuclear receptor subfamily 4 group A 0.0024 0.0003 0.0004
Schistosoma mansoni thyroid hormone receptor 0.0051 0.0041 0.0065
Leishmania major mitochondrial DNA polymerase beta-PAK, putative 0.014 0.0169 0.0696
Onchocerca volvulus Huntingtin homolog 0.0126 0.0149 0.1095
Brugia malayi intermediate filament protein 0.0052 0.0043 0.0041
Echinococcus granulosus aldehyde dehydrogenase mitochondrial 0.0365 0.0492 0.0775
Echinococcus granulosus rhodopsin orphan GPCR 0.0178 0.0224 0.0353
Trichomonas vaginalis high-affinity cGMP-specific 3,5-cyclic phosphodiesterase, putative 0.006 0.0054 0.0396
Loa Loa (eye worm) hypothetical protein 0.0178 0.0224 0.0222
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0178 0.0224 0.0353
Loa Loa (eye worm) cytoplasmic intermediate filament protein 0.0028 0.0008 0.0006
Echinococcus multilocularis muscleblind protein 0.1184 0.1667 0.2624
Echinococcus granulosus g-protein coupled receptor 0.0178 0.0224 0.0353
Brugia malayi hypothetical protein 0.0027 0.0007 0.0004
Echinococcus granulosus guanine nucleotide binding protein Gs subunit 0.041 0.0557 0.0876
Trichomonas vaginalis ap endonuclease, putative 0.0038 0.0023 0.0168
Trypanosoma cruzi cAMP specific phosphodiesterase, putative 0.006 0.0054 0.0219
Echinococcus granulosus orexin receptor type 2 0.0178 0.0224 0.0353
Loa Loa (eye worm) nuclear hormone receptor-like 1 0.0027 0.0007 0.0004
Brugia malayi Integrin alpha cytoplasmic region family protein 0.0043 0.003 0.0027
Trichomonas vaginalis calcium/calmodulin-dependent 3,5-cyclic nucleotide phosphodiesterase, putative 0.006 0.0054 0.0396
Schistosoma mansoni o-acyltransferase (membrane bound) domain containing protein 0.0383 0.0518 0.0816
Leishmania major hypothetical protein, conserved 0.0215 0.0276 0.1138
Mycobacterium tuberculosis Adenosylmethionine-8-amino-7-oxononanoate aminotransferase BioA 0.0307 0.0409 0.2051
Echinococcus granulosus dual 3'5' cyclic AMP and GMP phosphodiesterase 0.006 0.0054 0.0084
Onchocerca volvulus 0.0052 0.0042 0.0299
Mycobacterium ulcerans cytochrome P450 124A1, Cyp124A1 0.004 0.0025 0.0109
Onchocerca volvulus Bile acid receptor homolog 0.0051 0.0041 0.0292
Mycobacterium ulcerans cytochrome P450 51B1 Cyp51B1 0.004 0.0025 0.0109
Leishmania major mitogen activated protein kinase 4, putative;with=GeneDB:LmxM19.1440 0.011 0.0126 0.0517
Loa Loa (eye worm) hypothetical protein 0.0178 0.0224 0.0222
Mycobacterium ulcerans cytochrome p450 150 cyp150 0.004 0.0025 0.0109
Brugia malayi Probable 3',5'-cyclic phosphodiesterase C32E12.2, putative 0.0026 0.0006 0.0004
Mycobacterium ulcerans esterase/lipase LipP 0.0215 0.0276 0.5424
Loa Loa (eye worm) follicle stimulating hormone receptor 0.0858 0.1199 0.1197
Mycobacterium ulcerans L-lysine aminotransferase 0.0044 0.0031 0.0231
Echinococcus granulosus tachykinin peptides receptor 99D 0.0178 0.0224 0.0353
Brugia malayi Nuclear hormone receptor family member nhr-1 0.0051 0.0041 0.0039
Loa Loa (eye worm) hypothetical protein 0.0178 0.0224 0.0222
Schistosoma mansoni Cys-loop ligand gated ion channel subunit 0.0028 0.0008 0.0013
Trichomonas vaginalis esterase, putative 0.0215 0.0276 0.206
Brugia malayi Melatonin receptor type 1A 0.0178 0.0224 0.0222
Echinococcus granulosus Nuclear hormone receptor family member nhr 41 0.0051 0.0041 0.0065
Brugia malayi Nuclear hormone receptor family member nhr-31 0.0051 0.0041 0.0039
Brugia malayi beta-lactamase family protein 0.0215 0.0276 0.0274
Loa Loa (eye worm) hypothetical protein 0.0051 0.0041 0.0039
Brugia malayi Neurotransmitter-gated ion-channel ligand binding domain containing protein 0.0052 0.0042 0.004
Loa Loa (eye worm) hypothetical protein 0.0043 0.003 0.0028
Trichomonas vaginalis high-affinity cGMP-specific 3,5-cyclic phosphodiesterase, putative 0.006 0.0054 0.0396
Giardia lamblia Neurogenic locus notch-like protein 0.0043 0.003 0.0429
Loa Loa (eye worm) hypothetical protein 0.0031 0.0012 0.001
Schistosoma mansoni hypothetical protein 0.0164 0.0204 0.0321
Echinococcus granulosus nicotinic acetylcholine receptor subunit alpha 8 0.0052 0.0042 0.0067
Brugia malayi glutamate-gated chloride channel alpha3A subunit, putative 0.0028 0.0008 0.0006
Trichomonas vaginalis calcium/calmodulin-dependent 3,5-cyclic nucleotide phosphodiesterase, putative 0.006 0.0054 0.0396
Schistosoma mansoni ubiquitin-specific peptidase 8 (C19 family) 0.0151 0.0185 0.029
Mycobacterium ulcerans hypothetical protein 0.0156 0.0192 0.3637
Mycobacterium tuberculosis Probable cytochrome P450 123 Cyp123 0.004 0.0025 0.0055
Trichomonas vaginalis chromodomain helicase DNA binding protein, putative 0.0026 0.0006 0.0038
Loa Loa (eye worm) latrophilin receptor protein 2 0.0031 0.0012 0.001
Mycobacterium tuberculosis Probable cytochrome P450 139 Cyp139 0.004 0.0025 0.0055
Mycobacterium ulcerans 4-aminobutyrate aminotransferase 0.0044 0.0031 0.0231
Brugia malayi calcium-independent alpha-latrotoxin receptor 2, putative 0.0031 0.0012 0.001
Trichomonas vaginalis chromodomain helicase DNA binding protein, putative 0.0026 0.0006 0.0038
Mycobacterium leprae DIHYDROLIPOAMIDE DEHYDROGENASE LPD (LIPOAMIDE REDUCTASE (NADH)) (LIPOYL DEHYDROGENASE) (DIHYDROLIPOYL DEHYDROGENASE) (DIAPHORASE 0.0116 0.0135 0.3062
Brugia malayi Nuclear hormone receptor family member nhr-41 0.0051 0.0041 0.0039
Brugia malayi Nuclear hormone receptor family member nhr-25 0.0051 0.0041 0.0039
Echinococcus multilocularis cpg binding protein 0.0123 0.0144 0.0227
Loa Loa (eye worm) glutathione reductase 0.0046 0.0034 0.0032
Echinococcus granulosus hepatocyte nuclear factor 4 alpha 0.0051 0.0041 0.0065
Echinococcus granulosus histone acetyltransferase KAT2B 0.0149 0.0181 0.0286
Onchocerca volvulus 0.0116 0.0134 0.099
Leishmania major aldehyde dehydrogenase, mitochondrial precursor 0.0365 0.0492 0.2032
Schistosoma mansoni hepatocyte nuclear factor 4-alpha (hnf-4-alpha) 0.0024 0.0003 0.0004
Echinococcus granulosus Basic leucine zipper bZIP transcription 0.0322 0.043 0.0677
Echinococcus multilocularis rhodopsin orphan GPCR 0.0178 0.0224 0.0353
Mycobacterium tuberculosis Conserved hypothetical protein 0.0156 0.0192 0.0922
Brugia malayi Neurotransmitter-gated ion-channel transmembrane region family protein 0.0052 0.0042 0.004
Mycobacterium ulcerans cytochrome P450 123A3 Cyp123A3 0.004 0.0025 0.0109
Loa Loa (eye worm) hypothetical protein 0.0027 0.0007 0.0004
Schistosoma mansoni aldehyde dehydrogenase 0.0365 0.0492 0.0775
Brugia malayi Cation transporter family protein 0.0052 0.0042 0.004
Loa Loa (eye worm) hhat protein 0.0383 0.0518 0.0516
Echinococcus multilocularis neuropeptide receptor 0.0178 0.0224 0.0353
Echinococcus multilocularis nuclear receptor 2DBD gamma 0.0024 0.0003 0.0004
Loa Loa (eye worm) MBOAT family protein 0.0383 0.0518 0.0516
Loa Loa (eye worm) hypothetical protein 0.1184 0.1667 0.1666
Brugia malayi EGF-like domain containing protein 0.0043 0.003 0.0028
Schistosoma mansoni o-acyltransferase (membrane bound) domain containing protein 0.0383 0.0518 0.0816
Onchocerca volvulus 0.0051 0.0041 0.0292
Loa Loa (eye worm) hypothetical protein 0.0178 0.0224 0.0222
Plasmodium vivax ornithine aminotransferase, putative 0.0044 0.0031 0.044
Schistosoma mansoni nAChR subunit (ShAR1-alpha-like) 0.0052 0.0042 0.0067
Echinococcus multilocularis biogenic amine (5HT) receptor 0.0178 0.0224 0.0353
Onchocerca volvulus Steroid hormone receptor family member cnr14 homolog 0.0051 0.0041 0.0292
Schistosoma mansoni nAChR subunit 0.0052 0.0042 0.0067
Echinococcus multilocularis guanine nucleotide binding protein G(s) subunit 0.041 0.0557 0.0876
Trypanosoma cruzi mitochondrial DNA polymerase beta, putative 0.0296 0.0393 0.1619
Trichomonas vaginalis bromodomain-containing protein, putative 0.0045 0.0033 0.0239
Echinococcus multilocularis GPCR, family 2 0.0031 0.0012 0.002
Echinococcus granulosus neuropeptide receptor 0.0178 0.0224 0.0353
Trichomonas vaginalis high-affinity cGMP-specific 3,5-cyclic phosphodiesterase, putative 0.006 0.0054 0.0396
Brugia malayi GnHR receptor homolog 0.0178 0.0224 0.0222
Plasmodium vivax thioredoxin reductase, putative 0.0046 0.0034 0.0504
Plasmodium vivax histone acetyltransferase GCN5, putative 0.0045 0.0033 0.0478
Toxoplasma gondii hypothetical protein 0.0048 0.0037 0.0555
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0178 0.0224 0.0353
Brugia malayi MH2 domain containing protein 0.0123 0.0145 0.0142
Echinococcus multilocularis serotonin receptor 0.0178 0.0224 0.0353
Loa Loa (eye worm) nucleolar RNA-associated protein alpha 0.0299 0.0397 0.0395
Mycobacterium leprae PROBABLE ADENOSYLMETHIONINE-8-AMINO-7-OXONONANOATE AMINOTRANSFERASE BIOA 0.0307 0.0409 1
Leishmania major cytochrome p450-like protein 0.004 0.0025 0.01
Mycobacterium leprae Probable 4-aminobutyrate aminotransferase GabT (GAMMA-AMINO-N-BUTYRATE TRANSAMINASE) (GABA TRANSAMINASE) (GLUTAMATE:SUCCINIC SEM 0.0044 0.0031 0.0414
Leishmania major mitogen activated protein kinase, putative,map kinase, putative 0.011 0.0126 0.0517
Mycobacterium tuberculosis NADPH-dependent mycothiol reductase Mtr 0.0046 0.0034 0.0102
Loa Loa (eye worm) hypothetical protein 0.0151 0.0185 0.0182
Echinococcus multilocularis tumor protein p63 0.0662 0.0918 0.1445
Loa Loa (eye worm) integrin alpha pat-2 0.0089 0.0097 0.0094
Echinococcus multilocularis Peptidase C19, ubiquitin carboxyl terminal hydrolase 2 0.0151 0.0185 0.029
Onchocerca volvulus 0.0178 0.0224 0.1661
Loa Loa (eye worm) hypothetical protein 0.0178 0.0224 0.0222
Leishmania major myo-inositol-1(or 4)-monophosphatase 1, putative 0.0036 0.002 0.0079
Loa Loa (eye worm) ACC-1 protein 0.0052 0.0042 0.004
Schistosoma mansoni transcription factor LCR-F1 0.0322 0.043 0.0677
Echinococcus granulosus diacylglycerol O acyltransferase 1 0.0383 0.0518 0.0816
Schistosoma mansoni FTZ-F1 nuclear receptor-like protein 0.0051 0.0041 0.0065
Schistosoma mansoni rab6-interacting 0.0041 0.0027 0.0042
Schistosoma mansoni nuclear hormone receptor 0.0051 0.0041 0.0065
Brugia malayi putative neuropeptide receptor NPR1 0.0178 0.0224 0.0222
Brugia malayi Serotonin receptor 0.0178 0.0224 0.0222
Trichomonas vaginalis conserved hypothetical protein 0.0052 0.0043 0.0318
Chlamydia trachomatis glutamate-1-semialdehyde-2,1-aminomutase 0.0044 0.0031 0.5
Mycobacterium tuberculosis Probable esterase/lipase LipP 0.0215 0.0276 0.1362
Echinococcus multilocularis Cys loop ligand gated ion channel subunit 0.0052 0.0042 0.0067
Brugia malayi Ligand-binding domain of nuclear hormone receptor family protein 0.0051 0.0041 0.0039
Loa Loa (eye worm) hypothetical protein 0.0126 0.0149 0.0146
Echinococcus granulosus cadherin EGF LAG seven pass G type receptor 0.0031 0.0012 0.002
Trichomonas vaginalis cAMP and cAMP-inhibited cGMP 3,5-cyclic phosphodiesterase, putative 0.0041 0.0026 0.0193
Trichomonas vaginalis Clan CA, family C19, ubiquitin hydrolase-like cysteine peptidase 0.0151 0.0185 0.1375
Loa Loa (eye worm) hypothetical protein 0.0043 0.003 0.0028
Toxoplasma gondii aldehyde dehydrogenase 0.0365 0.0492 0.9488
Loa Loa (eye worm) hypothetical protein 0.0028 0.0008 0.0006
Loa Loa (eye worm) hypothetical protein 0.0178 0.0224 0.0222
Giardia lamblia Tenascin-37 0.0043 0.003 0.0429
Loa Loa (eye worm) hypothetical protein 0.0215 0.0276 0.0274
Schistosoma mansoni hypothetical protein 0.0067 0.0064 0.0101
Echinococcus granulosus integrin beta 2 0.0992 0.1392 0.2191
Brugia malayi G-protein coupled receptor 0.0178 0.0224 0.0222
Onchocerca volvulus Nuclear receptor subfamily 6 group A member 1 homolog 0.0024 0.0003 0.0002
Loa Loa (eye worm) hypothetical protein 0.0178 0.0224 0.0222
Schistosoma mansoni biogenic amine receptor 0.0178 0.0224 0.0353
Schistosoma mansoni cpg binding protein 0.0123 0.0144 0.0227
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0178 0.0224 0.0353
Brugia malayi G-protein coupled receptor 0.0178 0.0224 0.0222
Loa Loa (eye worm) hypothetical protein 0.0027 0.0007 0.0004
Brugia malayi Nuclear hormone receptor family member nhr-19 0.0051 0.0041 0.0039
Mycobacterium tuberculosis Probable oxidoreductase 0.0116 0.0135 0.0628
Loa Loa (eye worm) neuropeptide F receptor 0.0178 0.0224 0.0222
Loa Loa (eye worm) hypothetical protein 0.0178 0.0224 0.0222
Brugia malayi Doublecortin family protein 0.0041 0.0027 0.0024
Brugia malayi Nuclear hormone receptor-like 1 0.0027 0.0007 0.0004
Schistosoma mansoni cpg binding protein 0.0123 0.0144 0.0227
Brugia malayi Cytochrome P450 family protein 0.0058 0.0051 0.0049
Mycobacterium tuberculosis NAD(P)H quinone reductase LpdA 0.0116 0.0135 0.0628
Brugia malayi Neurotransmitter-gated ion-channel transmembrane region family protein 0.0028 0.0008 0.0006
Brugia malayi hypothetical protein 0.0032 0.0014 0.0012
Mycobacterium tuberculosis Putative ferredoxin reductase 0.0105 0.0118 0.0541
Brugia malayi Nuclear hormone receptor family member nhr-14 0.0051 0.0041 0.0039
Echinococcus granulosus DNA apurinic or apyrimidinic site lyase 0.0038 0.0023 0.0036
Brugia malayi acetyltransferase, GNAT family protein 0.0153 0.0188 0.0185
Mycobacterium tuberculosis Probable cytochrome P450 140 Cyp140 0.004 0.0025 0.0055
Entamoeba histolytica myo-inositol monophosphatase, putative 0.0036 0.002 0.037
Brugia malayi acetylcholine receptor alpha subunit precursor, putative 0.0052 0.0042 0.004
Echinococcus multilocularis sex peptide receptor 0.0178 0.0224 0.0353
Loa Loa (eye worm) hypothetical protein 0.0051 0.0041 0.0039
Mycobacterium tuberculosis Probable cytochrome P450 monooxygenase 142 Cyp142 0.004 0.0025 0.0055
Plasmodium falciparum ataxin-2 like protein, putative 0.005 0.0039 0.0608
Schistosoma mansoni acetylcholine receptor-related 0.0024 0.0002 0.0004
Echinococcus multilocularis glycine receptor subunit alpha 1 0.0052 0.0042 0.0067
Brugia malayi hypothetical protein 0.0178 0.0224 0.0222
Schistosoma mansoni neurotransmitter gated ion channel 0.0024 0.0002 0.0004
Onchocerca volvulus 0.0052 0.0042 0.0299
Loa Loa (eye worm) hypothetical protein 0.0052 0.0042 0.004
Echinococcus multilocularis integrin alpha ps 0.0089 0.0097 0.0152
Trichomonas vaginalis high-affinity cGMP-specific 3,5-cyclic phosphodiesterase, putative 0.0026 0.0006 0.0039
Loa Loa (eye worm) acetylcholine receptor alpha subunit 0.0052 0.0042 0.004
Trypanosoma cruzi cAMP specific phosphodiesterase, putative 0.006 0.0054 0.0219
Leishmania major trypanothione reductase 0.0046 0.0034 0.0138
Onchocerca volvulus 0.0178 0.0224 0.1661
Mycobacterium ulcerans glutaminase 0.0266 0.035 0.699
Toxoplasma gondii thioredoxin reductase 0.0046 0.0034 0.0504
Schistosoma mansoni neuropeptide receptor 0.0178 0.0224 0.0353
Loa Loa (eye worm) hypothetical protein 0.0178 0.0224 0.0222
Loa Loa (eye worm) nuclear hormone receptor family member nhr-49 0.0051 0.0041 0.0039
Schistosoma mansoni aldehyde dehydrogenase 0.0365 0.0492 0.0775
Echinococcus granulosus fmrfamide receptor 0.0178 0.0224 0.0353
Trichomonas vaginalis calcium/calmodulin-dependent 3,5-cyclic nucleotide phosphodiesterase, putative 0.006 0.0054 0.0396
Giardia lamblia Neurogenic locus Notch protein precursor 0.0043 0.003 0.0429
Leishmania major mitogen-activated protein kinase 3, putative,map kinase 3, putative 0.1709 0.242 1
Mycobacterium tuberculosis Probable cytochrome P450 132 Cyp132 0.004 0.0025 0.0055
Trypanosoma brucei cytochrome P450, putative 0.0058 0.0051 0.0177
Onchocerca volvulus 0.0122 0.0144 0.106
Brugia malayi 4-aminobutyrate aminotransferase, mitochondrial precursor 0.0044 0.0031 0.0028
Brugia malayi nuclear receptor NHR-88 0.0051 0.0041 0.0039
Loa Loa (eye worm) hypothetical protein 0.0028 0.0008 0.0006
Echinococcus multilocularis atpase aaa+ type core atpase aaa type core 0.1632 0.231 0.3635
Trichomonas vaginalis cAMP/cGMP cyclic nucleotide phosphodiesterase, putative 0.006 0.0054 0.0396
Echinococcus granulosus nuclear receptor 2DBD gamma 0.0051 0.0041 0.0065
Echinococcus multilocularis aldehyde dehydrogenase, mitochondrial 0.0365 0.0492 0.0775
Onchocerca volvulus 0.0178 0.0224 0.1661
Echinococcus granulosus allatostatin A receptor 0.0178 0.0224 0.0353
Brugia malayi Cation transporter family protein 0.0052 0.0042 0.004
Echinococcus granulosus Cys loop ligand gated ion channel subunit 0.0024 0.0002 0.0004
Loa Loa (eye worm) cytochrome P450 family protein 0.0058 0.0051 0.0049
Toxoplasma gondii hypothetical protein 0.0052 0.0043 0.0684
Brugia malayi Ubiquitin carboxyl-terminal hydrolase family protein 0.0151 0.0185 0.0182
Echinococcus multilocularis ecdysone induced protein 78C 0.0051 0.0041 0.0065
Echinococcus multilocularis hepatocyte nuclear factor 4 alpha 0.0051 0.0041 0.0065
Echinococcus multilocularis mitogen activated protein kinase 3 0.011 0.0126 0.0198
Trichomonas vaginalis CMGC family protein kinase 0.011 0.0126 0.0936
Echinococcus granulosus growth hormone secretagogue receptor type 1 0.0178 0.0224 0.0353
Echinococcus granulosus COUP TF:Svp nuclear hormone receptor 0.0051 0.0041 0.0065
Toxoplasma gondii exonuclease III APE 0.0038 0.0023 0.0292
Mycobacterium ulcerans exodeoxyribonuclease III protein XthA 0.0038 0.0023 0.007
Loa Loa (eye worm) nicotinic acetylcholine receptor non-alpha subunit 0.0052 0.0042 0.004
Loa Loa (eye worm) hypothetical protein 0.0178 0.0224 0.0222
Mycobacterium ulcerans cytochrome P450 144A4 Cyp144A4 0.004 0.0025 0.0109
Mycobacterium tuberculosis Probable cytochrome P450 125 Cyp125 0.004 0.0025 0.0055
Echinococcus multilocularis muscleblind protein 1 0.1184 0.1667 0.2624
Mycobacterium ulcerans adenosylmethionine-8-amino-7-oxononanoate aminotransferase 0.0307 0.0409 0.8228
Schistosoma mansoni muscarinic acetylcholine (GAR) receptor 0.0178 0.0224 0.0353
Brugia malayi putative neuropeptide receptor 0.0178 0.0224 0.0222
Mycobacterium ulcerans 4-aminobutyrate aminotransferase 0.0044 0.0031 0.0231
Loa Loa (eye worm) intermediate filament tail domain-containing protein 0.0052 0.0043 0.0041
Trypanosoma cruzi mitochondrial DNA polymerase beta-PAK, putative 0.0042 0.0028 0.0112
Schistosoma mansoni eyes absent homolog 0.009 0.0097 0.0152
Mycobacterium tuberculosis Probable esterase LipL 0.0215 0.0276 0.1362
Mycobacterium ulcerans cytochrome P450 143A4 Cyp143A4 0.004 0.0025 0.0109
Loa Loa (eye worm) hypothetical protein 0.0052 0.0042 0.004
Schistosoma mansoni ancient conserved domain protein 2 (cyclin m2) 0.0178 0.0224 0.0353
Mycobacterium ulcerans cytochrome P450 187A5 Cyp187A5 0.004 0.0025 0.0109
Echinococcus granulosus Polycystic kidney disease protein 0.0041 0.0027 0.0042
Onchocerca volvulus 0.0052 0.0043 0.0306
Loa Loa (eye worm) hypothetical protein 0.0052 0.0042 0.004
Schistosoma mansoni photoreceptor-specific nuclear receptor related 0.0051 0.0041 0.0065
Onchocerca volvulus 0.0215 0.0276 0.205
Trypanosoma cruzi ubiquitin carboxyl-terminal hydrolase, putative 0.0151 0.0185 0.076
Loa Loa (eye worm) hypothetical protein 0.0067 0.0064 0.0062
Echinococcus granulosus Aminotransferase class III 0.0044 0.0031 0.0048
Echinococcus multilocularis somatostatin receptor 0.0178 0.0224 0.0353
Echinococcus granulosus lipoxygenase domain containing protein 0.0041 0.0027 0.0042
Trichomonas vaginalis cGMP-dependent 3,5-cyclic phosphodiesterase, putative 0.006 0.0054 0.0396
Echinococcus multilocularis peptide (allatostatin:somatostatin) 0.0178 0.0224 0.0353
Trypanosoma cruzi cytochrome P450, putative 0.0058 0.0051 0.0208
Loa Loa (eye worm) membrane bound O-acyltransferase domain containing 1 0.0383 0.0518 0.0516
Brugia malayi excitatory GABA receptor EXP-1A 0.0052 0.0042 0.004
Toxoplasma gondii LsmAD domain-containing protein 0.005 0.0039 0.0608
Brugia malayi Neurotransmitter-gated ion-channel ligand binding domain containing protein 0.0052 0.0042 0.004
Entamoeba histolytica acetyltransferase, GNAT family 0.0041 0.0027 0.0514
Schistosoma mansoni opsin-like receptor 0.0178 0.0224 0.0353
Echinococcus multilocularis fmrfamide receptor 0.0178 0.0224 0.0353
Trypanosoma brucei mitogen activated protein kinase 4, putative 0.011 0.0126 0.0488
Treponema pallidum alginate O-acetylation protein (algI) 0.0383 0.0518 1
Echinococcus granulosus protein cysteine N palmitoyltransferase 0.445 0.6354 1
Loa Loa (eye worm) hypothetical protein 0.0028 0.0008 0.0006
Echinococcus multilocularis nicotinic acetylcholine receptor subunit type 0.0024 0.0002 0.0004
Schistosoma mansoni integrin alpha-ps 0.0047 0.0035 0.0055
Loa Loa (eye worm) hypothetical protein 0.0028 0.0008 0.0006
Onchocerca volvulus 0.0097 0.0107 0.0785
Loa Loa (eye worm) hypothetical protein 0.0051 0.0041 0.0039
Schistosoma mansoni Cys-loop ligand gated ion channel subunit 0.0052 0.0042 0.0067
Echinococcus multilocularis ornithine aminotransferase 0.0044 0.0031 0.0048
Echinococcus granulosus neuropeptide s receptor 0.0657 0.0911 0.1434
Entamoeba histolytica membrane-bound O-acyltransferase (MBOAT ) family protein 0.0383 0.0518 1
Schistosoma mansoni amine GPCR 0.0178 0.0224 0.0353
Echinococcus multilocularis neuropeptides capa receptor 0.0178 0.0224 0.0353
Echinococcus multilocularis arachidonate 5 lipoxygenase 0.018 0.0227 0.0357
Schistosoma mansoni integrin alpha-ps 0.0089 0.0097 0.0152
Loa Loa (eye worm) hypothetical protein 0.0178 0.0224 0.0222
Onchocerca volvulus 0.0178 0.0224 0.1661
Plasmodium falciparum ataxin-2 like protein, putative 0.005 0.0039 0.0608
Echinococcus multilocularis nAChR subunit 0.0028 0.0008 0.0013
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0178 0.0224 0.0353
Brugia malayi Neurotransmitter-gated ion-channel ligand binding domain containing protein 0.0052 0.0042 0.004
Schistosoma mansoni neurotransmitter gated ion channel 0.0024 0.0002 0.0004
Schistosoma mansoni gcn5proteinral control of amino-acid synthesis 5-like 2 gcnl2 0.0153 0.0188 0.0295
Echinococcus multilocularis glycine receptor subunit alpha 1 0.0052 0.0042 0.0067
Loa Loa (eye worm) hypothetical protein 0.0178 0.0224 0.0222
Giardia lamblia Ubiquitin carboxyl-terminal hydrolase 4 0.0151 0.0185 1
Echinococcus granulosus 7tm_1 domain containing protein 0.0178 0.0224 0.0353
Leishmania major glycerol uptake protein, putative 0.0383 0.0518 0.214
Echinococcus granulosus mitogen activated protein kinase 3 0.011 0.0126 0.0198
Mycobacterium tuberculosis Conserved protein 0.0215 0.0276 0.1362
Loa Loa (eye worm) GABA receptor subunit 0.0028 0.0008 0.0006
Brugia malayi Cytochrome P450 family protein 0.004 0.0025 0.0023
Schistosoma mansoni biogenic amine (dopamine) receptor 0.0178 0.0224 0.0353
Trichomonas vaginalis conserved hypothetical protein 0.0026 0.0006 0.0038
Loa Loa (eye worm) hypothetical protein 0.0215 0.0276 0.0274
Schistosoma mansoni myosin xvIII 0.0178 0.0224 0.0353
Schistosoma mansoni integrin alpha-4 0.0383 0.0517 0.0814
Schistosoma mansoni diacylglycerol O-acyltransferase 1 0.0383 0.0518 0.0816
Loa Loa (eye worm) hypothetical protein 0.0703 0.0977 0.0974
Entamoeba histolytica hypothetical protein 0.0322 0.043 0.8301
Loa Loa (eye worm) hypothetical protein 0.0051 0.0041 0.0039
Echinococcus granulosus peptide allatostatin:somatostatin 0.0178 0.0224 0.0353
Loa Loa (eye worm) 5-hydroxytryptamine 2C receptor 0.0178 0.0224 0.0222
Echinococcus granulosus nuclear receptor nhr 48 0.0024 0.0003 0.0004
Brugia malayi Serotonin/octopamine receptor family protein 7 0.0178 0.0224 0.0222
Schistosoma mansoni neuropeptide F-like receptor 0.0178 0.0224 0.0353
Loa Loa (eye worm) hypothetical protein 0.0051 0.0041 0.0039
Loa Loa (eye worm) hypothetical protein 0.0025 0.0004 0.0002
Echinococcus granulosus nuclear receptor 2DBD gamma 0.0024 0.0003 0.0004
Brugia malayi RNA, U transporter 1 0.008 0.0082 0.008
Schistosoma mansoni nAChR subunit 0.0052 0.0042 0.0067
Echinococcus multilocularis conserved hypothetical protein 0.1404 0.1982 0.312
Loa Loa (eye worm) hypothetical protein 0.0178 0.0224 0.0222
Leishmania major glycerol uptake protein, putative 0.0383 0.0518 0.214
Echinococcus granulosus glycine receptor subunit alpha 1 0.0052 0.0042 0.0067
Mycobacterium tuberculosis Possible cytochrome P450 135B1 Cyp135B1 0.004 0.0025 0.0055
Plasmodium falciparum histone acetyltransferase GCN5 0.0041 0.0027 0.0373
Schistosoma mansoni glutaminase 0.0266 0.035 0.0551
Trypanosoma cruzi cytochrome p450-like protein, putative 0.004 0.0025 0.01
Schistosoma mansoni hypothetical protein 0.0143 0.0174 0.0273
Loa Loa (eye worm) TYRA-2 protein 0.0178 0.0224 0.0222
Mycobacterium tuberculosis Probable glutamate-1-semialdehyde 2,1-aminomutase HemL (GSA) (glutamate-1-semialdehyde aminotransferase) (GSA-at) 0.0044 0.0031 0.0085
Echinococcus granulosus importin subunit beta 1 0.0028 0.0008 0.0013
Echinococcus granulosus glycine receptor subunit beta 0.0052 0.0042 0.0067
Loa Loa (eye worm) hypothetical protein 0.0178 0.0224 0.0222
Echinococcus multilocularis histone lysine methyltransferase setb histone lysine methyltransferase eggless 0.0122 0.0144 0.0226
Echinococcus granulosus nicotinic acetylcholine receptor beta 1 subunit 0.0052 0.0042 0.0067
Onchocerca volvulus 0.0178 0.0224 0.1661
Echinococcus granulosus lipoxygenase domain containing protein 0.0041 0.0027 0.0042
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0178 0.0224 0.0353
Leishmania major glycerol uptake protein, putative 0.0383 0.0518 0.214
Echinococcus granulosus rhodopsin orphan GPCR 0.0178 0.0224 0.0353
Echinococcus multilocularis g protein coupled receptor 0.0178 0.0224 0.0353
Brugia malayi hypothetical protein 0.0041 0.0027 0.0024
Loa Loa (eye worm) excitatory GABA receptor EXP-1A 0.0052 0.0042 0.004
Trichomonas vaginalis rod cGMP-specific 3,5-cyclic phosphodiesterase, putative 0.006 0.0054 0.0396
Echinococcus multilocularis fibrillin 1 0.0043 0.003 0.0047
Loa Loa (eye worm) CXXC zinc finger family protein 0.0116 0.0134 0.0132
Echinococcus multilocularis lipoxygenase domain containing protein 0.0041 0.0027 0.0042
Mycobacterium ulcerans cytochrome P450 136A2 Cyp136A2 0.004 0.0025 0.0109
Echinococcus granulosus mitogen activated protein kinase 11 0.1709 0.242 0.3809
Loa Loa (eye worm) hypothetical protein 0.0028 0.0008 0.0006
Leishmania major mitochondrial DNA polymerase beta 0.0296 0.0393 0.1619
Echinococcus multilocularis G protein coupled 5 hydroxytryptamine receptor 0.0178 0.0224 0.0353
Loa Loa (eye worm) integrin beta-2 0.1244 0.1754 0.1752
Toxoplasma gondii histone lysine acetyltransferase GCN5-B 0.0045 0.0033 0.0478
Schistosoma mansoni biogenic amine (octopamine/dopamine) receptor 0.0178 0.0224 0.0353
Trichomonas vaginalis calcium/calmodulin-dependent 3,5-cyclic nucleotide phosphodiesterase, putative 0.006 0.0054 0.0396
Echinococcus granulosus ornithine aminotransferase 0.0044 0.0031 0.0048
Trichomonas vaginalis cyclic nucleotide phosphodiesterase, putative 0.006 0.0054 0.0396
Onchocerca volvulus Protein ultraspiracle homolog 0.0051 0.0041 0.0292
Entamoeba histolytica hypothetical protein 0.0383 0.0518 1
Trypanosoma brucei glycerol uptake protein, putative 0.0383 0.0518 0.2115
Leishmania major hypothetical protein, conserved 0.0383 0.0518 0.214
Echinococcus multilocularis pyroglutamylated rfamide peptide receptor 0.0178 0.0224 0.0353
Trichomonas vaginalis cAMP-specific phosphodiesterase, putative 0.0041 0.0026 0.0193
Loa Loa (eye worm) hypothetical protein 0.0052 0.0042 0.004
Brugia malayi Integrin alpha pat-2 precursor 0.0089 0.0097 0.0094
Echinococcus multilocularis neuropeptides capa receptor 0.0178 0.0224 0.0353
Loa Loa (eye worm) hypothetical protein 0.0027 0.0007 0.0004
Loa Loa (eye worm) hypothetical protein 0.0178 0.0224 0.0222
Echinococcus multilocularis Nuclear hormone receptor family member nhr 41 0.0051 0.0041 0.0065
Brugia malayi acetylcholine receptor protein, alpha-like chain, putative 0.0052 0.0042 0.004
Brugia malayi EGF-like domain containing protein 0.0043 0.003 0.0028
Echinococcus multilocularis protein jagged 2 0.0043 0.003 0.0047
Loa Loa (eye worm) hypothetical protein 0.0098 0.0108 0.0106
Brugia malayi hypothetical protein 0.0703 0.0977 0.0974
Loa Loa (eye worm) hypothetical protein 0.0178 0.0224 0.0222
Loa Loa (eye worm) hypothetical protein 0.0178 0.0224 0.0222
Schistosoma mansoni thyrotropin-releasing hormone receptor 0.0178 0.0224 0.0353
Mycobacterium ulcerans cytochrome P450 140A5 Cyp140A5 0.004 0.0025 0.0109
Echinococcus granulosus hypothetical protein 0.1582 0.2239 0.3523
Brugia malayi neuropeptide F receptor 0.0178 0.0224 0.0222
Schistosoma mansoni Cys-loop ligand gated ion channel subunit 0.0052 0.0042 0.0067
Echinococcus multilocularis histone lysine N methyltransferase SETMAR 0.0122 0.0144 0.0226
Schistosoma mansoni family S12 unassigned peptidase (S12 family) 0.0215 0.0276 0.0435
Echinococcus multilocularis Basic leucine zipper (bZIP) transcription 0.0322 0.043 0.0677
Echinococcus granulosus nuclear receptor subfamily 1 group D 0.0027 0.0007 0.0011
Loa Loa (eye worm) hypothetical protein 0.009 0.0097 0.0094
Echinococcus multilocularis DNA (apurinic or apyrimidinic site) lyase 0.0038 0.0023 0.0036
Echinococcus granulosus beta LACTamase domain containing family member 0.0215 0.0276 0.0435
Loa Loa (eye worm) hypothetical protein 0.0126 0.0149 0.0146
Mycobacterium tuberculosis Probable aminotransferase 0.0307 0.0409 0.2051
Brugia malayi hypothetical protein 0.0178 0.0224 0.0222
Mycobacterium leprae putative cytochrome p450 0.004 0.0025 0.0268
Echinococcus multilocularis survival motor neuron protein 1 0.0703 0.0977 0.1537
Schistosoma mansoni nAChR subunit 0.0024 0.0002 0.0004
Mycobacterium ulcerans hypothetical protein 0.0215 0.0276 0.5424
Echinococcus multilocularis beta LACTamase domain containing family member 0.0215 0.0276 0.0435
Echinococcus multilocularis rhodopsin orphan GPCR 0.0178 0.0224 0.0353
Mycobacterium tuberculosis Probable reductase 0.0105 0.0118 0.0541
Mycobacterium tuberculosis Cytochrome P450 121 Cyp121 0.004 0.0025 0.0055
Echinococcus multilocularis growth hormone secretagogue receptor type 1 0.0178 0.0224 0.0353
Echinococcus granulosus integrin alpha ps 0.0043 0.003 0.0047
Echinococcus granulosus dnaJ subfamily B 0.1244 0.1753 0.2759
Brugia malayi Muscleblind-like protein 0.1184 0.1667 0.1666
Echinococcus multilocularis Membrane bound O acyl transferase, MBOAT 0.0383 0.0518 0.0816
Echinococcus multilocularis RUN 0.0041 0.0027 0.0042
Loa Loa (eye worm) hypothetical protein 0.0051 0.0042 0.004
Loa Loa (eye worm) hypothetical protein 0.0052 0.0042 0.004
Trypanosoma cruzi trypanothione reductase, putative 0.0046 0.0034 0.0138
Echinococcus multilocularis tm gpcr rhodopsin gpcr rhodopsin superfamily 0.0178 0.0224 0.0353
Brugia malayi CXXC zinc finger family protein 0.0116 0.0134 0.0132
Trypanosoma cruzi mitochondrial DNA polymerase beta-PAK, putative 0.0051 0.0041 0.0166
Schistosoma mansoni Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) 0.041 0.0557 0.0876
Echinococcus granulosus arachidonate 5 lipoxygenase 0.018 0.0227 0.0357
Schistosoma mansoni cpg binding protein 0.0116 0.0134 0.0212
Mycobacterium ulcerans cytochrome P450 185A4 Cyp185A4 0.0058 0.0051 0.0661
Mycobacterium tuberculosis Probable aldehyde dehydrogenase 0.0365 0.0492 0.2487
Onchocerca volvulus 0.0143 0.0174 0.1284
Echinococcus granulosus thyrotropin releasing hormone receptor 0.0178 0.0224 0.0353
Mycobacterium ulcerans aldehyde dehydrogenase 0.0365 0.0492 1
Mycobacterium ulcerans ornithine aminotransferase RocD1 and RocD2 0.0044 0.0031 0.0231
Schistosoma mansoni hypothetical protein 0.0041 0.0027 0.0042
Echinococcus multilocularis g protein coupled receptor 0.0178 0.0224 0.0353
Loa Loa (eye worm) hypothetical protein 0.0178 0.0224 0.0222
Echinococcus multilocularis serotonin receptor 0.0178 0.0224 0.0353
Echinococcus multilocularis sterol O acyltransferase 1 0.0383 0.0518 0.0816
Brugia malayi hypothetical protein 0.009 0.0097 0.0094
Brugia malayi Hypothetical glycine receptor like protein T20B12.9 in chromosome III 0.0028 0.0008 0.0006
Loa Loa (eye worm) hypothetical protein 0.0028 0.0008 0.0006
Echinococcus granulosus tumor protein p63 0.0662 0.0918 0.1445
Loa Loa (eye worm) hypothetical protein 0.0122 0.0144 0.0142
Loa Loa (eye worm) inositol-1 0.0036 0.002 0.0017
Brugia malayi Cation transporter family protein 0.0052 0.0042 0.004
Loa Loa (eye worm) hypothetical protein 0.0178 0.0224 0.0222
Brugia malayi beta-lactamase 0.0215 0.0276 0.0274
Loa Loa (eye worm) hypothetical protein 0.0097 0.0107 0.0105
Loa Loa (eye worm) hypothetical protein 0.0178 0.0224 0.0222
Loa Loa (eye worm) hypothetical protein 0.0052 0.0042 0.004
Echinococcus multilocularis COUP TF:Svp nuclear hormone receptor 0.0051 0.0041 0.0065
Schistosoma mansoni peptide (FMRFamide/somatostatin)-like receptor 0.0178 0.0224 0.0353
Echinococcus multilocularis neuronal acetylcholine receptor subunit alpha 4 0.0052 0.0042 0.0067
Brugia malayi nuclear hormone receptor 0.0051 0.0041 0.0039
Schistosoma mansoni neuropeptide receptor 0.0178 0.0224 0.0353
Leishmania major hypothetical protein, conserved 0.005 0.0039 0.016
Mycobacterium ulcerans glutamate-1-semialdehyde aminotransferase 0.0044 0.0031 0.0231
Trichomonas vaginalis chromodomain helicase DNA binding protein, putative 0.0026 0.0006 0.0038
Loa Loa (eye worm) hypothetical protein 0.005 0.0039 0.0037
Trichomonas vaginalis conserved hypothetical protein 0.0383 0.0518 0.3872
Brugia malayi Integrin beta pat-3 precursor 0.1244 0.1754 0.1752
Schistosoma mansoni microtubule-associated protein tau 0.2046 0.2905 0.4572
Schistosoma mansoni mixed-lineage leukemia protein mll 0.0033 0.0016 0.0025
Brugia malayi G protein-coupled receptor 0.0178 0.0224 0.0222
Trypanosoma cruzi mitogen-activated protein kinase 11, putative 0.011 0.0126 0.0517
Onchocerca volvulus Dopamine\/Ecdysteroid receptor homolog 0.0178 0.0224 0.1661
Trichomonas vaginalis conserved hypothetical protein 0.0026 0.0006 0.0038
Onchocerca volvulus Huntingtin homolog 0.0126 0.0149 0.1095
Echinococcus granulosus integrin alpha ps 0.0089 0.0097 0.0152
Schistosoma mansoni inositol monophosphatase 0.0036 0.002 0.0031
Schistosoma mansoni Tr4/Tr2 (homologue) 0.0051 0.0041 0.0065
Schistosoma mansoni lamin 0.0052 0.0043 0.0068
Loa Loa (eye worm) CYP4Cod1 0.0058 0.0051 0.0049
Plasmodium falciparum thioredoxin reductase 0.0046 0.0034 0.0504
Onchocerca volvulus 0.0028 0.0008 0.0043
Plasmodium vivax AP endonuclease (DNA-[apurinic or apyrimidinic site] lyase), putative 0.0038 0.0023 0.0292
Brugia malayi Neurotransmitter-gated ion-channel transmembrane region family protein 0.0052 0.0042 0.004
Mycobacterium tuberculosis Cytochrome P450 51 Cyp51 (CYPL1) (P450-L1A1) (sterol 14-alpha demethylase) (lanosterol 14-alpha demethylase) (P450-14DM) 0.004 0.0025 0.0055
Brugia malayi Importin beta-1 subunit 0.0028 0.0008 0.0006
Schistosoma mansoni hypothetical protein 0.0178 0.0224 0.0353
Echinococcus multilocularis diuretic hormone 44 receptor GPRdih2 0.0031 0.0012 0.002
Trypanosoma cruzi mitochondrial DNA polymerase beta, putative 0.0296 0.0393 0.1619
Echinococcus multilocularis G protein coupled receptor 139 0.0178 0.0224 0.0353
Schistosoma mansoni neuropeptide F-like receptor 0.0178 0.0224 0.0353
Loa Loa (eye worm) MBOAT family protein 0.0383 0.0518 0.0516
Trypanosoma brucei inositol-1(or 4)-monophosphatase 1, putative 0.0036 0.002 0.0048
Schistosoma mansoni biogenic amine receptor 0.0178 0.0224 0.0353
Brugia malayi nuclear receptor RXR 0.0027 0.0007 0.0004
Schistosoma mansoni camp/cgmp cyclic nucleotide phosphodiesterase 0.006 0.0054 0.0084
Echinococcus granulosus Peptidase C19 ubiquitin carboxyl terminal hydrolase 2 0.0151 0.0185 0.029
Brugia malayi Nuclear hormone receptor-like 1 0.0051 0.0041 0.0039
Onchocerca volvulus 0.0178 0.0224 0.1661
Schistosoma mansoni zinc finger protein 0.0024 0.0003 0.0004
Trichomonas vaginalis cAMP-specific 3,5-cyclic phosphodiesterase, putative 0.006 0.0054 0.0396
Schistosoma mansoni hypothetical protein 0.0164 0.0204 0.0321
Toxoplasma gondii ornithine aminotransferase, mitochondrial precursor, putative 0.0044 0.0031 0.044
Echinococcus granulosus Nuclear hormone receptor HR96 0.0024 0.0003 0.0004
Brugia malayi Hypothetical 52.5 kDa protein ZK945.1 in chromosome II, putative 0.0215 0.0276 0.0274
Trypanosoma cruzi myo-inositol-1(or 4)-monophosphatase 1, putative 0.0036 0.002 0.0079
Echinococcus multilocularis FTZ F1 nuclear receptor protein 0.0051 0.0041 0.0065
Echinococcus multilocularis nuclear receptor nhr 48 0.0024 0.0003 0.0004
Trichomonas vaginalis conserved hypothetical protein 0.006 0.0054 0.0396
Onchocerca volvulus 0.0178 0.0224 0.1661
Brugia malayi hypothetical protein 0.0178 0.0224 0.0222
Mycobacterium ulcerans cytochrome P450 188A3 Cyp188A3 0.004 0.0025 0.0109
Plasmodium vivax hypothetical protein, conserved 0.0215 0.0276 0.525
Loa Loa (eye worm) cytochrome P450 family protein 0.0156 0.0192 0.0189
Trypanosoma brucei trypanothione reductase 0.0046 0.0034 0.0107
Loa Loa (eye worm) hypothetical protein 0.0052 0.0042 0.004
Echinococcus granulosus ecdysone induced protein 78C 0.0051 0.0041 0.0065
Brugia malayi acetylcholine receptor, alpha-type subunit unc-38 precursor 0.0052 0.0042 0.004
Echinococcus multilocularis neuropeptide receptor A26 0.0657 0.0911 0.1434
Onchocerca volvulus 0.0383 0.0518 0.3864
Echinococcus granulosus G protein coupled 5 hydroxytryptamine receptor 0.0178 0.0224 0.0353
Echinococcus multilocularis glycine receptor subunit beta 0.0052 0.0042 0.0067
Trypanosoma cruzi myo-inositol-1(or 4)-monophosphatase 1, putative 0.0036 0.002 0.0079
Echinococcus granulosus neuropeptide receptor A26 0.0657 0.0911 0.1434
Trichomonas vaginalis Clan CA, family C19, ubiquitin hydrolase-like cysteine peptidase 0.0151 0.0185 0.1375
Leishmania major glycerol uptake protein, putative 0.0383 0.0518 0.214
Schistosoma mansoni neuropeptide f receptor 76f 0.0178 0.0224 0.0353
Loa Loa (eye worm) hypothetical protein 0.0215 0.0276 0.0274
Echinococcus granulosus o acyltransferase membrane bound domain 0.0383 0.0518 0.0816
Brugia malayi hypothetical protein 0.0178 0.0224 0.0222
Brugia malayi steroid hormone receptor 0.0051 0.0041 0.0039
Schistosoma mansoni lipoxygenase 0.0107 0.0122 0.0191
Mycobacterium ulcerans cytochrome P450 191A3 Cyp191A3 0.004 0.0025 0.0109
Echinococcus multilocularis nicotinic acetylcholine receptor subunit alpha 8 0.0052 0.0042 0.0067
Echinococcus multilocularis nAChR subunit 0.0052 0.0042 0.0067
Loa Loa (eye worm) beta-lactamase 0.0215 0.0276 0.0274
Schistosoma mansoni Cys-loop ligand gated ion channel subunit 0.0052 0.0042 0.0067
Mycobacterium leprae Probable Acetylornithine aminotransferase ArgD 0.0044 0.0031 0.0414
Echinococcus granulosus g protein coupled receptor 0.0178 0.0224 0.0353
Schistosoma mansoni neuropeptide receptor 0.0178 0.0224 0.0353
Trichomonas vaginalis rod cGMP-specific 3,5-cyclic phosphodiesterase, putative 0.006 0.0054 0.0396
Schistosoma mansoni ecdysone-induced protein 78c (dr-78) 0.0027 0.0007 0.0011
Echinococcus granulosus tm gpcr rhodopsin 0.0178 0.0224 0.0353
Trichomonas vaginalis conserved hypothetical protein 0.0383 0.0518 0.3872
Brugia malayi follicle stimulating hormone receptor 0.0858 0.1199 0.1197
Trichomonas vaginalis cGMP-dependent 3,5-cyclic phosphodiesterase, putative 0.006 0.0054 0.0396
Trichomonas vaginalis conserved hypothetical protein 0.0383 0.0518 0.3872
Echinococcus multilocularis tm gpcr rhodopsin gpcr rhodopsin superfamily 0.0178 0.0224 0.0353
Loa Loa (eye worm) hypothetical protein 0.0047 0.0035 0.0033
Echinococcus granulosus o acyltransferase membrane bound domain 0.0383 0.0518 0.0816
Onchocerca volvulus 0.0178 0.0224 0.1661
Echinococcus granulosus ubiquitin carboxyl terminal hydrolase 8 0.0151 0.0185 0.029
Schistosoma mansoni importin beta-1 0.0028 0.0008 0.0013
Schistosoma mansoni histone-lysine n-methyltransferase setb1 0.0122 0.0144 0.0226
Echinococcus granulosus pyroglutamylated rfamide peptide receptor 0.0178 0.0224 0.0353
Loa Loa (eye worm) steroid hormone receptor 0.0051 0.0041 0.0039
Schistosoma mansoni Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) 0.041 0.0557 0.0876
Leishmania major lanosterol 14-alpha-demethylase, putative 0.004 0.0025 0.01
Mycobacterium ulcerans aldehyde dehydrogenase 0.0365 0.0492 1
Leishmania major apurinic/apyrimidinic endonuclease-redox protein 0.0038 0.0023 0.0093
Echinococcus granulosus retinoic acid receptor rxr beta a 0.0051 0.0041 0.0065
Echinococcus multilocularis nuclear receptor subfamily 4 group A 0.0024 0.0003 0.0004
Echinococcus granulosus glycine receptor subunit beta 0.0052 0.0042 0.0067
Schistosoma mansoni nAChR subunit 0.0052 0.0042 0.0067
Echinococcus multilocularis nuclear receptor subfamily 1 group D 0.0027 0.0007 0.0011
Trypanosoma brucei cAMP-specific phosphodiesterase 0.006 0.0054 0.0188
Schistosoma mansoni integrin alpha 0.0089 0.0097 0.0152
Trichomonas vaginalis cAMP-specific 3,5-cyclic phosphodiesterase, putative 0.006 0.0054 0.0396
Brugia malayi Neurotransmitter-gated ion-channel ligand binding domain containing protein 0.0052 0.0042 0.004
Mycobacterium leprae Conserved hypothetical protein 0.004 0.0025 0.0268
Echinococcus multilocularis lysophospholipid acyltransferase 7 0.0383 0.0518 0.0816
Echinococcus granulosus thioredoxin glutathione reductase 0.0046 0.0034 0.0053
Trypanosoma cruzi glycerol uptake protein, putative 0.0383 0.0518 0.214
Brugia malayi Nuclear hormone receptor family member nhr-40 0.0051 0.0041 0.0039
Schistosoma mansoni integrin beta subunit 0.0789 0.11 0.1731
Brugia malayi gonadotropin-releasing hormone receptor 2 0.0178 0.0224 0.0222
Loa Loa (eye worm) hypothetical protein 0.0178 0.0224 0.0222
Brugia malayi Steroid receptor seven-up type 2 0.0051 0.0041 0.0039
Echinococcus granulosus neuropeptides capa receptor 0.0178 0.0224 0.0353
Echinococcus multilocularis guanine nucleotide binding protein G(s) subunit 0.041 0.0557 0.0876
Echinococcus granulosus o acyltransferase membrane bound domain 0.0383 0.0518 0.0816
Brugia malayi diacylglycerol acyltransferase 0.0383 0.0518 0.0516
Echinococcus granulosus cpg binding protein 0.0123 0.0144 0.0227
Loa Loa (eye worm) MH2 domain-containing protein 0.0123 0.0145 0.0142
Trichomonas vaginalis chromodomain-helicase-DNA-binding protein, putative 0.0026 0.0006 0.0038
Mycobacterium ulcerans cytochrome P450 105Q4 Cyp105Q4 0.004 0.0025 0.0109
Echinococcus granulosus guanine nucleotide binding protein Gs subunit 0.041 0.0557 0.0876
Schistosoma mansoni hypothetical protein 0.0031 0.0012 0.002
Brugia malayi G protein-coupled receptor F59B2.13 0.0178 0.0224 0.0222
Onchocerca volvulus 0.0028 0.0008 0.0043
Onchocerca volvulus 0.0178 0.0224 0.1661
Mycobacterium tuberculosis Probable dehydrogenase 0.0105 0.0118 0.0541
Echinococcus multilocularis importin subunit beta 1 0.0028 0.0008 0.0013
Echinococcus multilocularis ornithine aminotransferase 0.0044 0.0031 0.0048
Schistosoma mansoni amine GPCR 0.0178 0.0224 0.0353
Schistosoma mansoni cytochrome P450 0.004 0.0025 0.0039
Echinococcus granulosus sterol O acyltransferase 1 0.0383 0.0518 0.0816
Entamoeba histolytica vacuolar protein sorting 26 0.0383 0.0518 1
Echinococcus granulosus nicotinic acetylcholine receptor alpha subunit 0.0052 0.0042 0.0067
Leishmania major glycerol uptake protein, putative 0.0383 0.0518 0.214
Echinococcus granulosus FTZ F1 nuclear receptor protein 0.0051 0.0041 0.0065
Schistosoma mansoni cgmp-dependent 35-cyclic phosphodiesterase 0.0026 0.0006 0.0009
Brugia malayi Dopamine receptor protein 1, putative (partial) 0.0178 0.0224 0.0222
Echinococcus granulosus 7TM GPCR rhodopsin 0.0178 0.0224 0.0353
Giardia lamblia High cysteine protein 0.0043 0.003 0.0429
Echinococcus granulosus alpha 1A adrenergic receptor 0.0178 0.0224 0.0353
Trichomonas vaginalis conserved hypothetical protein 0.0026 0.0006 0.0038
Trichomonas vaginalis myo inositol monophosphatase, putative 0.0036 0.002 0.0143
Brugia malayi ORL1-like opioid receptor 0.0178 0.0224 0.0222
Loa Loa (eye worm) hypothetical protein 0.0178 0.0224 0.0222
Loa Loa (eye worm) hypothetical protein 0.0041 0.0027 0.0024
Trichomonas vaginalis conserved hypothetical protein 0.0026 0.0006 0.0038
Echinococcus multilocularis ubiquitin specific protease 41 0.0151 0.0185 0.029
Brugia malayi G-protein-linked acetylcholine receptor protein 2, putative 0.0178 0.0224 0.0222
Brugia malayi Ligand-binding domain of nuclear hormone receptor family protein 0.0051 0.0041 0.0039
Trichomonas vaginalis porcupine, putative 0.0383 0.0518 0.3872
Echinococcus multilocularis lamin 0.0052 0.0043 0.0068
Loa Loa (eye worm) hypothetical protein 0.0383 0.0518 0.0516
Plasmodium vivax SET domain protein, putative 0.0122 0.0144 0.2659
Loa Loa (eye worm) beta-LACTamase domain containing family member 0.0215 0.0276 0.0274
Echinococcus granulosus neuronal acetylcholine receptor subunit alpha 4 0.0052 0.0042 0.0067
Echinococcus multilocularis histone lysine N methyltransferase MLL3 0.004 0.0026 0.0041
Onchocerca volvulus 0.0052 0.0042 0.0299
Schistosoma mansoni ornithine--oxo-acid transaminase 0.0044 0.0031 0.0048
Loa Loa (eye worm) hypothetical protein 0.0178 0.0224 0.0222
Brugia malayi Corticotropin releasing factor receptor 2 precursor, putative 0.0098 0.0108 0.0106
Echinococcus multilocularis mitogen activated protein kinase 14 0.1709 0.242 0.3809
Schistosoma mansoni ap endonuclease 0.0038 0.0023 0.0036
Schistosoma mansoni cellular tumor antigen P53 0.0097 0.0107 0.0169
Trichomonas vaginalis CMGC family protein kinase 0.011 0.0126 0.0936
Trichomonas vaginalis acetylornithine aminotransferase, putative 0.0307 0.0409 0.305
Loa Loa (eye worm) nuclear hormone receptor family member nhr-41 0.0051 0.0041 0.0039
Loa Loa (eye worm) ACC-1 protein 0.0052 0.0042 0.004
Trichomonas vaginalis D-aminoacylase, putative 0.0215 0.0276 0.206
Loa Loa (eye worm) hypothetical protein 0.0051 0.0041 0.0039
Echinococcus granulosus Membrane bound O acyl transferase MBOAT 0.0383 0.0518 0.0816
Echinococcus granulosus inositol monophosphatase 1 0.0036 0.002 0.0031
Schistosoma mansoni peptide (allatostatin)-like receptor 0.0178 0.0224 0.0353
Trypanosoma brucei mitochondrial DNA polymerase beta 0.0296 0.0393 0.1593
Schistosoma mansoni histone-lysine n-methyltransferase suv9 0.0122 0.0144 0.0226
Brugia malayi neuropeptide F receptor 0.0178 0.0224 0.0222
Trichomonas vaginalis cat eye syndrome critical region protein 2, cscr2, putative 0.0045 0.0033 0.0239
Brugia malayi gamma-aminobutyric-acid receptor beta subunit precursor 0.0052 0.0042 0.004
Echinococcus granulosus thyroid hormone receptor alpha 0.0024 0.0003 0.0004
Trypanosoma cruzi hypothetical protein, conserved 0.0215 0.0276 0.1138
Trichomonas vaginalis chromodomain-helicase-DNA-binding protein, putative 0.0026 0.0006 0.0038
Onchocerca volvulus 0.0954 0.1338 1
Echinococcus multilocularis Nuclear hormone receptor HR96 0.0024 0.0003 0.0004
Mycobacterium leprae PROBABLE GLUTAMATE-1-SEMIALDEHYDE 2,1-AMINOMUTASE HEML (GSA) (GLUTAMATE-1-SEMIALDEHYDE AMINOTRANSFERASE) (GSA-AT) 0.0044 0.0031 0.0414
Onchocerca volvulus 0.0024 0.0003 0.0002
Echinococcus granulosus membrane bound acyltransferase:hhat 0.0383 0.0518 0.0816
Loa Loa (eye worm) hypothetical protein 0.0051 0.0041 0.0039
Mycobacterium tuberculosis Possible conserved lipoprotein LpqK 0.0215 0.0276 0.1362
Echinococcus granulosus g protein coupled receptor 0.0178 0.0224 0.0353
Loa Loa (eye worm) LGC-31 protein 0.0052 0.0042 0.004
Schistosoma mansoni nAChR subunit (ShAR1-beta2-like) 0.0052 0.0042 0.0067
Echinococcus multilocularis rhodopsin orphan GPCR 0.0178 0.0224 0.0353
Echinococcus granulosus neuropeptide FF receptor 2 0.0178 0.0224 0.0353
Loa Loa (eye worm) hypothetical protein 0.0052 0.0042 0.004
Loa Loa (eye worm) MBOAT family protein 0.445 0.6354 0.6354
Wolbachia endosymbiont of Brugia malayi exonuclease III 0.0038 0.0023 0.3042
Echinococcus multilocularis snurportin 1 0.0299 0.0397 0.0624
Echinococcus multilocularis rhodopsin orphan GPCR 0.0178 0.0224 0.0353
Toxoplasma gondii histone lysine methyltransferase SET/SUV39 0.0122 0.0144 0.2659
Onchocerca volvulus 0.0178 0.0224 0.1661
Schistosoma mansoni amine GPCR 0.0178 0.0224 0.0353
Echinococcus granulosus Nuclear hormone receptor HR96 0.0024 0.0003 0.0004
Trypanosoma brucei ubiquitin carboxyl-terminal hydrolase, putative 0.0151 0.0185 0.0731
Onchocerca volvulus 0.0024 0.0003 0.0002
Mycobacterium ulcerans cytochrome P450 126A3 Cyp126A3 0.004 0.0025 0.0109
Trichomonas vaginalis penicillin-binding protein, putative 0.0215 0.0276 0.206
Echinococcus granulosus g protein linked acetylcholine receptor gar 2a 0.0178 0.0224 0.0353
Schistosoma mansoni biogenic amine receptor 0.0178 0.0224 0.0353
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0178 0.0224 0.0353
Loa Loa (eye worm) ligand-Gated ion Channel family member 0.0052 0.0042 0.004
Schistosoma mansoni nAChR subunit 0.0052 0.0042 0.0067
Brugia malayi EGF-like domain containing protein 0.0043 0.003 0.0028
Echinococcus granulosus RUN 0.0041 0.0027 0.0042
Loa Loa (eye worm) hypothetical protein 0.0178 0.0224 0.0222
Loa Loa (eye worm) hypothetical protein 0.0178 0.0224 0.0222
Loa Loa (eye worm) hypothetical protein 0.0178 0.0224 0.0222
Brugia malayi Unidentified vitellogenin-linked transcript protein 6, putative 0.0178 0.0224 0.0222
Echinococcus granulosus lamin dm0 0.0052 0.0043 0.0068
Echinococcus multilocularis glycine receptor subunit beta 0.0052 0.0042 0.0067
Trypanosoma cruzi Lanosterol 14-alpha demethylase 0.004 0.0025 0.01
Echinococcus multilocularis 0.004 0.0025 0.0039
Loa Loa (eye worm) melatonin receptor type 1A 0.0178 0.0224 0.0222
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0178 0.0224 0.0353
Loa Loa (eye worm) hypothetical protein 0.0052 0.0042 0.004
Entamoeba histolytica hypothetical protein, conserved 0.0383 0.0518 1
Echinococcus granulosus survival motor neuron protein 1 0.0703 0.0977 0.1537
Brugia malayi Neurotransmitter-gated ion-channel ligand binding domain containing protein 0.0052 0.0042 0.004
Loa Loa (eye worm) hypothetical protein 0.0026 0.0006 0.0004
Loa Loa (eye worm) hypothetical protein 0.009 0.0097 0.0094
Loa Loa (eye worm) hypothetical protein 0.0204 0.026 0.0258
Loa Loa (eye worm) hypothetical protein 0.0052 0.0042 0.004
Brugia malayi Neurotransmitter-gated ion-channel transmembrane region family protein 0.0052 0.0042 0.004
Echinococcus granulosus diuretic hormone 44 receptor GPRdih2 0.0031 0.0012 0.002
Schistosoma mansoni neuropeptide receptor 0.0178 0.0224 0.0353
Brugia malayi latrophilin 2 splice variant baaae 0.0067 0.0064 0.0062
Schistosoma mansoni biogenic amine (5HT) receptor 0.0178 0.0224 0.0353
Giardia lamblia Kinase, CMGC MAPK 0.011 0.0126 0.6364
Schistosoma mansoni growth hormone secretagogue receptor 0.0178 0.0224 0.0353
Schistosoma mansoni retinoid-x-receptor (RXR) 0.0051 0.0041 0.0065
Plasmodium falciparum ornithine aminotransferase 0.0044 0.0031 0.044
Loa Loa (eye worm) cytochrome P450 family protein 0.0058 0.0051 0.0049
Loa Loa (eye worm) hypothetical protein 0.0041 0.0027 0.0024
Trichomonas vaginalis rod cGMP-specific 3,5-cyclic phosphodiesterase, putative 0.006 0.0054 0.0396
Mycobacterium leprae PROBABLE NADH DEHYDROGENASE NDH 0.0105 0.0118 0.2636
Mycobacterium tuberculosis Probable cytochrome P450 141 Cyp141 0.004 0.0025 0.0055
Onchocerca volvulus 0.0178 0.0224 0.1661
Loa Loa (eye worm) hypothetical protein 0.0028 0.0008 0.0006
Mycobacterium ulcerans hypothetical protein 0.0307 0.0409 0.8228
Echinococcus multilocularis 7TM GPCR, rhodopsin 0.0178 0.0224 0.0353
Trichomonas vaginalis conserved hypothetical protein 0.0026 0.0006 0.0038
Echinococcus multilocularis dual 3',5' cyclic AMP and GMP phosphodiesterase 0.006 0.0054 0.0084
Toxoplasma gondii acyl-CoA:diacylglycerol acyltransferase 1-related enzyme 0.0383 0.0518 1
Echinococcus granulosus nAChR subunit 0.0052 0.0042 0.0067
Loa Loa (eye worm) thioredoxin reductase 0.0046 0.0034 0.0032
Brugia malayi MBOAT family protein 0.0383 0.0518 0.0516
Loa Loa (eye worm) diacylglycerol acyltransferase 0.0383 0.0518 0.0516
Loa Loa (eye worm) transcription factor SMAD2 0.0123 0.0145 0.0142
Echinococcus granulosus tm gpcr rhodopsin 0.0178 0.0224 0.0353
Schistosoma mansoni acetylcholine receptor subunit beta 0.0024 0.0002 0.0004
Trypanosoma cruzi apurinic/apyrimidinic endonuclease, putative 0.0038 0.0023 0.0093
Loa Loa (eye worm) exodeoxyribonuclease III family protein 0.0038 0.0023 0.0021
Echinococcus multilocularis lipoxygenase domain containing protein 0.0041 0.0027 0.0042
Trichomonas vaginalis penicillin-binding protein, putative 0.0215 0.0276 0.206
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0178 0.0224 0.0353
Loa Loa (eye worm) glutaminase 0.0266 0.035 0.0348
Brugia malayi hypothetical protein 0.0178 0.0224 0.0222
Echinococcus multilocularis microtubule associated protein 2 0.2046 0.2905 0.4572
Trypanosoma cruzi mitogen activated protein kinase 4, putative 0.011 0.0126 0.0517
Trichomonas vaginalis cGMP-specific 3,5-cyclic phosphodiesterase, putative 0.006 0.0054 0.0396

Activities

No activities found for this compound.

Phenotypes

Whole-cell/tissue/organism interactions

We have no records of whole-cell/tissue assays done with this compound What does this mean?

Many chemical entities in TDR Targets come from high-throughput screenings with whole cells or tissue samples, and not all assayed compounds have been tested against a single a single target protein, probably because they get ruled out during screening process. Even if these compounds may have not been of interest in the original screening, they may come as interesting leads for other screening assays. Furthermore, we may be able to propose drug-target associations using chemical similarities and network patterns.

Annotated phenotypes:

We have no manually annotated phenotypes for this drug. What does this mean? / Care to help?
In TDR Targets, information about phenotypes that are caused by drugs, or by genetic manipulation of cells (e.g. gene knockouts or knockdowns) is manually curated from the literature. These descriptions help to describe the potential of the target for drug development. If no information is available for this gene or if the information is incomplete, this may mean that i) the papers containing this information either appeared after the curation effort for this organism was carried out or they were inadvertently missed by curators; or that ii) the curation effort for this organism has not yet started.
 
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External resources for this compound

Bibliographic References

No literature references available for this target.

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