Detailed information for compound 59181

Basic information

Technical information
  • Name: Unnamed compound
  • MW: 400.486 | Formula: C23H29FN2O3
  • H donors: 2 H acceptors: 2 LogP: 4.87 Rotable bonds: 13
    Rule of 5 violations (Lipinski): 1
  • SMILES: FC[C@@H](NC(=O)[C@@H](NC(=O)OCc1ccccc1)CC(C)C)Cc1ccccc1
  • InChi: 1S/C23H29FN2O3/c1-17(2)13-21(26-23(28)29-16-19-11-7-4-8-12-19)22(27)25-20(15-24)14-18-9-5-3-6-10-18/h3-12,17,20-21H,13-16H2,1-2H3,(H,25,27)(H,26,28)/t20-,21-/m0/s1
  • InChiKey: YZNUXKIBNHXFRS-SFTDATJTSA-N  


Substructure search Similarity search

Network

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Synonyms

No synonyms found for this compound

Targets

Known targets for this compound

No curated genes were found associated with this compound

Predicted pathogen targets for this compound

By orthology
No druggable targets predicted by orthology data
By sequence similarity to non orthologous known druggable targets
No druggable targets predicted by sequence similarity
Obtained from network model

Ranking Plot

Putative Targets List

Species Potential target Raw Global Species
Brugia malayi P38 map kinase family protein 2 0.0462 0.1243 0.1231
Loa Loa (eye worm) CK1/CK1/CK1-A protein kinase 0.0227 0.0392 0.0388
Schistosoma mansoni serine/threonine protein kinase 0.0294 0.0636 0.0993
Entamoeba histolytica protein kinase domain containing protein 0.028 0.0583 0.1261
Entamoeba histolytica protein kinase, putative 0.0128 0.003 0.0065
Brugia malayi Protein kinase domain containing protein 0.0552 0.1573 0.1561
Toxoplasma gondii cell-cycle-associated protein kinase SRPK, putative 0.0123 0.0013 0.0017
Brugia malayi Dual-specificity tyrosine-phosphorylation regulated kinase 2 0.0179 0.0216 0.0203
Loa Loa (eye worm) CAMK/CAMKL/BRSK protein kinase 0.0176 0.0207 0.0203
Plasmodium vivax casein kinase 2, alpha subunit, putative 0.028 0.0583 0.2349
Echinococcus granulosus serine:threonine protein kinase PAK 4 0.059 0.1708 0.1955
Leishmania major protein kinase, putative 0.0193 0.0269 0.1034
Onchocerca volvulus Serine\/threonine protein kinase homolog 0.0725 0.2198 0.4415
Onchocerca volvulus 0.09 0.2835 0.5716
Giardia lamblia Kinase, NEK 0.0391 0.0986 0.3933
Schistosoma mansoni serine/threonine protein kinase 0.0196 0.0279 0.0424
Toxoplasma gondii histone kinase SNF1, putative 0.0176 0.0207 0.0455
Trichomonas vaginalis CAMK family protein kinase 0.0188 0.0248 0.0475
Loa Loa (eye worm) TK/FER protein kinase 0.0221 0.0369 0.0366
Echinococcus multilocularis receptor type tyrosine protein phosphatase 0.0126 0.0026 0.0024
Brugia malayi protein kinase C II. 0.073 0.2216 0.2206
Echinococcus granulosus serine:threonine protein kinase 0.0323 0.0739 0.0844
Leishmania major protein kinase, putative 0.042 0.109 0.4355
Loa Loa (eye worm) AGC/RSK/MSK protein kinase 0.0633 0.1866 0.1863
Brugia malayi serine/threonine protein kinase 6 0.042 0.109 0.1079
Entamoeba histolytica p21-activated kinase 0.0291 0.0624 0.135
Schistosoma mansoni chimerin-related rho-gtpase-activating protein 0.0225 0.0382 0.0588
Echinococcus multilocularis calcium:calmodulin dependent protein kinase I 0.019 0.0255 0.0281
Loa Loa (eye worm) hypothetical protein 0.0271 0.055 0.0546
Echinococcus granulosus casein kinase I alpha 0.0227 0.0392 0.0445
Trypanosoma cruzi aurora B kinase, putative 0.042 0.109 0.4068
Schistosoma mansoni serine/threonine protein kinase 0.0242 0.0446 0.0691
Schistosoma mansoni protein kinase 0.0232 0.0411 0.0634
Echinococcus granulosus tyrosine protein kinase HCK 0.0289 0.0615 0.0701
Trypanosoma cruzi mitogen-activated protein kinase 3, putative 0.0462 0.1243 0.4644
Echinococcus granulosus insulin receptor 0.1349 0.4467 0.512
Loa Loa (eye worm) TK/KIN16 protein kinase 0.1689 0.5699 0.5698
Loa Loa (eye worm) TK/FER protein kinase 0.0221 0.0369 0.0366
Onchocerca volvulus 0.0134 0.0053 0.0033
Trypanosoma cruzi 5'-AMP-activated protein kinase catalytic subunit alpha, putative 0.0176 0.0207 0.0731
Echinococcus granulosus neuroglian 0.0126 0.0026 0.0025
Loa Loa (eye worm) AGC/PDK1 protein kinase 0.0222 0.0374 0.037
Onchocerca volvulus 0.0221 0.0369 0.0679
Entamoeba histolytica protein kinase, putative 0.0123 0.0013 0.0028
Trypanosoma cruzi casein kinase, putative 0.0227 0.0392 0.1431
Toxoplasma gondii calcium-dependent protein kinase CDPK2B 0.0188 0.0248 0.055
Echinococcus multilocularis mitogen activated protein kinase 0.0229 0.0399 0.0442
Trichomonas vaginalis STE family protein kinase 0.0236 0.0425 0.086
Echinococcus multilocularis RNA directed DNA polymerase 0.0122 0.001 0.0007
Echinococcus multilocularis protein kinase c iota type 0.0981 0.313 0.3493
Loa Loa (eye worm) CAMK/PIM protein kinase 0.0725 0.2198 0.2195
Loa Loa (eye worm) calcium/calmodulin-dependent protein kinase subunit type II alpha 0.0332 0.0774 0.077
Echinococcus multilocularis titin 0.0147 0.01 0.0108
Loa Loa (eye worm) hypothetical protein 0.0318 0.0721 0.0717
Brugia malayi Protein kinase domain containing protein 0.0348 0.083 0.0818
Echinococcus multilocularis nervana 2 0.0724 0.2197 0.2451
Loa Loa (eye worm) AGC/PKG protein kinase 0.0174 0.02 0.0196
Loa Loa (eye worm) CAMK/CAMKL/CHK1 protein kinase 0.0765 0.2344 0.2341
Plasmodium falciparum serine/threonine protein kinase KIN 0.0176 0.0207 0.0819
Echinococcus multilocularis dual specificity protein kinase clk2 0.0193 0.0269 0.0296
Plasmodium vivax serine/threonine protein kinase 6, putative 0.042 0.109 0.4416
Loa Loa (eye worm) sex muscle abnormal protein 5 0.0195 0.0276 0.0272
Echinococcus multilocularis cGMP dependent protein kinase 1 0.0174 0.02 0.0219
Trichomonas vaginalis CMGC family protein kinase 0.0179 0.0216 0.0404
Echinococcus granulosus dual specificity 0.0179 0.0216 0.0243
Trypanosoma brucei aurora B kinase 0.042 0.109 0.2337
Echinococcus multilocularis hypothetical protein 0.0229 0.0398 0.0441
Echinococcus multilocularis ribosomal protein s6 kinase beta 1 0.0613 0.1792 0.1998
Echinococcus granulosus dual specificity 0.0348 0.083 0.0948
Loa Loa (eye worm) TK/FER protein kinase 0.0221 0.0369 0.0366
Toxoplasma gondii AGC kinase 0.0196 0.0279 0.062
Leishmania major serine/threonine-protein kinase, putative,protein kinase, putative 0.0348 0.083 0.3304
Schistosoma mansoni serine/threonine protein kinase 0.0852 0.266 0.422
Echinococcus multilocularis Serine:threonine protein kinase PLK4 0.0418 0.1083 0.1206
Loa Loa (eye worm) CMGC/GSK protein kinase 0.0368 0.0902 0.0899
Plasmodium falciparum calcium-dependent protein kinase 1 0.0188 0.0248 0.0989
Plasmodium falciparum calcium-dependent protein kinase 4 0.0188 0.0248 0.0989
Trypanosoma brucei polo-like protein kinase 0.0804 0.2486 0.5367
Loa Loa (eye worm) CAMK/CAMKL/AMPK protein kinase 0.0473 0.1285 0.1282
Schistosoma mansoni tyrosine kinase 0.1099 0.3559 0.5653
Trypanosoma brucei protein kinase, putative 0.0128 0.003 0.0037
Echinococcus multilocularis homeodomain interacting protein kinase 3 0.0242 0.0446 0.0494
Loa Loa (eye worm) hypothetical protein 0.0239 0.0435 0.0432
Giardia lamblia Kinase, AGC PKA 0.0797 0.2462 0.9902
Schistosoma mansoni serine/threonine protein kinase 0.0804 0.2486 0.3943
Schistosoma mansoni serine/threonine protein kinase 0.013 0.0037 0.0038
Loa Loa (eye worm) AGC/RSK/RSK protein kinase 0.0872 0.2733 0.273
Trypanosoma brucei STE/STE11 serine/threonine-protein kinase, putative 0.0182 0.0229 0.0469
Giardia lamblia Kinase, STE STE20 0.0236 0.0425 0.1665
Plasmodium falciparum NIMA related kinase 1 0.0391 0.0986 0.399
Echinococcus granulosus neuroglian 0.0266 0.0531 0.0605
Echinococcus multilocularis tyrosine protein kinase HCK 0.0289 0.0615 0.0683
Leishmania major serine/threonine protein kinase, putative,protein kinase, putative 0.0176 0.0207 0.0783
Echinococcus granulosus c-Jun N-terminal kinases 0.0785 0.2419 0.277
Loa Loa (eye worm) TK/FER protein kinase 0.0221 0.0369 0.0366
Echinococcus granulosus proto oncogene serine:threonine protein kinase 0.0725 0.2198 0.2517
Giardia lamblia Kinase, CAMK CAMKL 0.0176 0.0207 0.0783
Echinococcus multilocularis serine:threonine protein kinase N2 0.0129 0.0036 0.0036
Echinococcus granulosus casein kinase I alpha 0.0227 0.0392 0.0445
Entamoeba histolytica protein kinase, putative 0.0224 0.0381 0.0825
Trypanosoma cruzi casein kinase, putative 0.0227 0.0392 0.1431
Schistosoma mansoni Neurotrimin precursor (hNT) 0.0212 0.0337 0.0517
Loa Loa (eye worm) CAMK/MLCK protein kinase 0.0199 0.029 0.0287
Loa Loa (eye worm) calcium/calmodulin-dependent protein kinase ID 0.0188 0.0248 0.0245
Schistosoma mansoni tyrosine kinase 0.072 0.2182 0.3458
Schistosoma mansoni nephrin 0.0126 0.0026 0.002
Trichomonas vaginalis CK1 family protein kinase 0.0227 0.0392 0.0788
Entamoeba histolytica serine/threonine- protein kinase 6 , putative 0.042 0.109 0.2359
Trichomonas vaginalis CAMK family protein kinase 0.0176 0.0207 0.0384
Echinococcus multilocularis tyrosine protein kinase Fyn 0.04 0.102 0.1136
Onchocerca volvulus 0.0221 0.0369 0.0679
Echinococcus multilocularis STE20 serine:threonine protein kinase 0.0533 0.1503 0.1676
Giardia lamblia Kinase, CMGC CDK 0.0337 0.0792 0.3148
Loa Loa (eye worm) camk/mapkapk/mapkapk protein kinase 0.1186 0.3872 0.387
Brugia malayi STE20-like kinase MST 0.0763 0.2336 0.2326
Schistosoma mansoni serine/threonine protein kinase 0.0223 0.0375 0.0577
Echinococcus multilocularis serine:threonine protein kinase 3 0.0763 0.2336 0.2606
Brugia malayi intracellular kinase 0.0368 0.0902 0.089
Entamoeba histolytica protein kinase, putative 0.019 0.0255 0.0552
Echinococcus multilocularis 5' AMP activated protein kinase catalytic 0.0473 0.1285 0.1431
Echinococcus granulosus calcium:calmodulin dependent protein kinase 0.0797 0.2462 0.282
Loa Loa (eye worm) hypothetical protein 0.0427 0.1119 0.1116
Entamoeba histolytica PH domain containing protein kinase, putative 0.0852 0.2661 0.5758
Loa Loa (eye worm) TK/FER protein kinase 0.0524 0.1469 0.1465
Loa Loa (eye worm) hypothetical protein 0.0265 0.0527 0.0524
Plasmodium vivax serine/threonine protein kinase, putative 0.0123 0.0013 0.0031
Echinococcus multilocularis rho associated protein kinase 0.0973 0.31 0.3459
Trypanosoma brucei kinetoplastid kinetochore protein 19 0.0193 0.0269 0.0555
Trypanosoma cruzi kinetoplastid kinetochore protein 19, putative 0.0193 0.0269 0.0965
Trypanosoma cruzi NIMA-related kinase, putative 0.0128 0.003 0.0065
Toxoplasma gondii CMGC kinase, MAPK family (ERK) MAPK-1 0.0229 0.0399 0.0892
Schistosoma mansoni tyrosine kinase 0.0215 0.0348 0.0535
Trypanosoma brucei protein kinase A catalytic subunit, putative 0.0196 0.0279 0.0578
Echinococcus granulosus ribosomal protein s6 kinase beta 1 0.0613 0.1792 0.2051
Entamoeba histolytica protein kinase, putative 0.0184 0.0236 0.0511
Plasmodium vivax glycogen synthase kinase 3, putative 0.0368 0.0902 0.365
Echinococcus granulosus serine threonine protein kinase nrc 0.0797 0.2462 0.282
Echinococcus granulosus MAP kinase activated protein kinase 2 0.1186 0.3872 0.4438
Loa Loa (eye worm) hypothetical protein 0.0176 0.0207 0.0203
Echinococcus granulosus p21 activated protein kinase 1 Dpak1 0.0236 0.0425 0.0483
Echinococcus granulosus contactin 0.0126 0.0026 0.0025
Giardia lamblia Kinase, CMGC CDK 0.0337 0.0792 0.3148
Brugia malayi Protein kinase domain containing protein 0.0633 0.1866 0.1855
Trypanosoma brucei protein kinase, putative 0.0368 0.0902 0.1929
Echinococcus granulosus epidermal growth factor receptor 0.185 0.6285 0.7206
Echinococcus granulosus cAMP dependent protein kinase catalytic subunit 0.0196 0.0279 0.0316
Echinococcus granulosus ephrin type A receptor 4 A 0.0307 0.0681 0.0776
Brugia malayi Stress-activated protein kinase jnk-1 0.0785 0.2419 0.2409
Echinococcus multilocularis serine:threonine protein kinase MARK2 0.0552 0.1571 0.1751
Toxoplasma gondii AGC kinase 0.0196 0.0279 0.062
Entamoeba histolytica SH2-protein kinase domain containing protein 0.0184 0.0236 0.0511
Trypanosoma cruzi mitogen-activated protein kinase 11, putative 0.0229 0.0399 0.1459
Loa Loa (eye worm) CMGC/MAPK/ERK1 protein kinase 0.0229 0.0399 0.0396
Echinococcus multilocularis calcium:calmodulin dependent protein kinase type 0.0188 0.0248 0.0273
Loa Loa (eye worm) TK/ABL protein kinase 0.0643 0.1901 0.1898
Loa Loa (eye worm) hypothetical protein 0.0126 0.0026 0.0022
Trichomonas vaginalis AGC family protein kinase 0.1392 0.4621 1
Echinococcus multilocularis serine:threonine protein kinase N2 0.0613 0.1792 0.1998
Echinococcus multilocularis tyrosine protein kinase lyn tyrosine protein kinase blk 0.0484 0.1324 0.1475
Brugia malayi Protein kinase domain containing protein 0.0221 0.0369 0.0357
Trichomonas vaginalis CAMK family protein kinase 0.0176 0.0207 0.0384
Trichomonas vaginalis AGC family protein kinase 0.0633 0.1866 0.3999
Echinococcus granulosus serine:threonine protein kinase PAK 3 0.0236 0.0425 0.0483
Schistosoma mansoni serine/threonine protein kinase 0.042 0.109 0.1717
Loa Loa (eye worm) CMGC/SRPK protein kinase 0.0123 0.0013 0.0009
Schistosoma mansoni protein kinase 0.0193 0.0267 0.0405
Entamoeba histolytica hypothetical protein 0.0128 0.003 0.0065
Schistosoma mansoni serine/threonine protein kinase 0.0204 0.0307 0.0468
Schistosoma mansoni protein kinase 0.052 0.1456 0.23
Echinococcus granulosus serine:threonine protein kinase PAK 3 0.0236 0.0425 0.0483
Echinococcus granulosus protein kinase C gamma type 0.0739 0.225 0.2576
Loa Loa (eye worm) STE/STE20/MSN protein kinase 0.0193 0.0267 0.0263
Echinococcus granulosus serine:threonine protein kinase TAO1 0.0262 0.0517 0.0589
Echinococcus multilocularis tyrosine protein kinase Src42A 0.0484 0.1324 0.1475
Echinococcus multilocularis growth factor receptor bound protein 2 0.0195 0.0276 0.0304
Loa Loa (eye worm) STE/STE20/MST protein kinase 0.0763 0.2336 0.2333
Leishmania major cell division related protein kinase 2,cdc2-related kinase 0.0337 0.0792 0.3148
Trichomonas vaginalis CMGC family protein kinase 0.0229 0.0399 0.0804
Plasmodium falciparum cGMP-dependent protein kinase 0.0174 0.02 0.079
Echinococcus multilocularis mitogen activated protein kinase kinase kinase 0.0429 0.1123 0.125
Echinococcus multilocularis cGMP dependent protein kinase 1 0.0174 0.02 0.0219
Brugia malayi Immunoglobulin I-set domain containing protein 0.0774 0.2376 0.2366
Trypanosoma brucei NEK family Serine/threonine-protein kinase, putative 0.0128 0.003 0.0037
Echinococcus multilocularis serine threonine protein kinase nrc serine threonine protein kinase gad 0.0797 0.2462 0.2747
Trichomonas vaginalis CMGC family protein kinase 0.0229 0.0399 0.0804
Schistosoma mansoni serine/threonine protein kinase 0.0473 0.1285 0.2028
Leishmania major casein kinase II, putative 0.028 0.0583 0.2303
Trypanosoma cruzi Protein kinase B 0.0852 0.2661 1
Schistosoma mansoni development and differentiation-enhancing factor ddef 0.0139 0.007 0.009
Entamoeba histolytica protein kinase domain containing protein 0.0368 0.0902 0.1952
Onchocerca volvulus 0.0163 0.0158 0.0247
Echinococcus granulosus tyrosine kinase 0.04 0.102 0.1166
Brugia malayi Protein kinase domain containing protein 0.0346 0.0822 0.081
Echinococcus multilocularis tyrosine protein kinase Fyn 0.0484 0.1324 0.1475
Loa Loa (eye worm) hypothetical protein 0.0122 0.001 0.0006
Plasmodium falciparum calcium-dependent protein kinase 2 0.0188 0.0248 0.0989
Echinococcus multilocularis tyrosine protein kinase Fyn 0.0484 0.1324 0.1475
Echinococcus multilocularis basement membrane specific heparan sulfate 0.0212 0.0337 0.0372
Echinococcus granulosus Protein kinase C brain isozyme 0.0852 0.266 0.3047
Brugia malayi Tyrosine-protein kinase abl-1 0.0466 0.1259 0.1248
Echinococcus multilocularis protein tyrosine kinase 0.0615 0.1799 0.2005
Trypanosoma brucei rac serine-threonine kinase, putative 0.1392 0.4621 1
Schistosoma mansoni neuroglian 0.0126 0.0026 0.002
Trichomonas vaginalis STE family protein kinase 0.0391 0.0986 0.2081
Loa Loa (eye worm) hypothetical protein 0.054 0.153 0.1526
Entamoeba histolytica protein kinase, putative 0.042 0.109 0.2359
Plasmodium vivax protein kinase, putative 0.0135 0.0057 0.021
Echinococcus multilocularis receptor type tyrosine protein phosphatase F 0.0126 0.0026 0.0024
Schistosoma mansoni serine/threonine protein kinase 0.073 0.2216 0.3513
Brugia malayi Protein kinase domain 0.0236 0.0425 0.0412
Giardia lamblia Kinase, PLK 0.0804 0.2486 1
Trichomonas vaginalis CAMK family protein kinase 0.0176 0.0207 0.0384
Echinococcus granulosus N chimaerin 0.0225 0.0382 0.0434
Giardia lamblia Kinase, STE STE20 0.0232 0.041 0.1604
Echinococcus granulosus calcium activated potassium channel 0.0302 0.0663 0.0756
Schistosoma mansoni receptor tyrosine phosphatase type r2a 0.0126 0.0026 0.002
Giardia lamblia Kinase, CMGC MAPK 0.0229 0.0399 0.1562
Echinococcus granulosus arf GAP with SH3 domain ANK repeat and PH 0.0139 0.007 0.0075
Echinococcus multilocularis casein kinase I delta 0.0227 0.0392 0.0434
Trichomonas vaginalis CAMK family protein kinase 0.0176 0.0207 0.0384
Leishmania major protein kinase, putative 0.0188 0.0248 0.0952
Brugia malayi protein kinase C3,putative 0.0441 0.1169 0.1158
Leishmania major mitogen activated protein kinase, putative,map kinase, putative 0.0229 0.0399 0.1562
Trichomonas vaginalis AGC family protein kinase 0.0222 0.0374 0.0749
Echinococcus multilocularis raf serine:threonine protein kinase 0.0223 0.0375 0.0414
Echinococcus granulosus phosphorylase kinase gamma subunit 0.0204 0.0307 0.0347
Trichomonas vaginalis CAMK family protein kinase 0.0804 0.2486 0.5349
Loa Loa (eye worm) hypothetical protein 0.0312 0.0701 0.0698
Echinococcus multilocularis tyrosine protein kinase ABL1 0.0643 0.1901 0.212
Echinococcus granulosus cAMP dependent protein kinase catalytic subunit 0.0196 0.0279 0.0316
Schistosoma mansoni tyrosine kinase 0.0434 0.1143 0.1802
Entamoeba histolytica hypothetical protein 0.0128 0.003 0.0065
Trichomonas vaginalis CAMK family protein kinase 0.0361 0.0876 0.1843
Giardia lamblia Kinase, CDC7 0.013 0.0037 0.0098
Trypanosoma brucei kinetoplastid kinetochore protein 10 0.0193 0.0269 0.0555
Loa Loa (eye worm) AGC/PKC/ALPHA protein kinase 0.0199 0.0289 0.0285
Brugia malayi hypothetical protein 0.0221 0.0369 0.0357
Trichomonas vaginalis AGC family protein kinase 0.042 0.109 0.2309
Plasmodium vivax casein kinase 1, putative 0.0227 0.0392 0.1573
Toxoplasma gondii aurora kinase 0.042 0.109 0.2456
Leishmania major casein kinase, putative 0.0227 0.0392 0.1532
Echinococcus granulosus 3'partial|tyrosine protein kinase Fgr 0.0484 0.1324 0.1515
Brugia malayi SH2 domain containing protein 0.0221 0.0369 0.0357
Plasmodium vivax cAMP-dependent protein kinase catalytic subunit, putative 0.0196 0.0279 0.1114
Loa Loa (eye worm) hypothetical protein 0.104 0.3345 0.3342
Schistosoma mansoni serine/threonine protein kinase 0.0765 0.2344 0.3716
Echinococcus multilocularis mitogen activated protein kinase 11 0.0462 0.1243 0.1384
Onchocerca volvulus 0.0425 0.1112 0.2195
Trypanosoma cruzi cAMP-dependent protein kinase catalytic subunit 3 0.0196 0.0279 0.1005
Loa Loa (eye worm) hypothetical protein 0.0414 0.1071 0.1067
Echinococcus granulosus serine:threonine protein kinase MARK2 0.0552 0.1571 0.1798
Trypanosoma cruzi Serine/threonine-protein kinase NEK17, putative 0.0128 0.003 0.0065
Trichomonas vaginalis CMGC family protein kinase 0.028 0.0583 0.1203
Loa Loa (eye worm) TK protein kinase 0.0289 0.0615 0.0612
Echinococcus multilocularis mitogen activated protein kinase 11 0.0462 0.1243 0.1384
Echinococcus multilocularis tyrosine protein kinase Src64B 0.0484 0.1324 0.1475
Echinococcus multilocularis tyrosine protein kinase 0.0349 0.0833 0.0927
Echinococcus granulosus roundabout 2 0.0339 0.0796 0.0909
Echinococcus granulosus cyclin dependent kinase 1 0.0337 0.0792 0.0904
Trypanosoma cruzi STE/STE20 serine/threonine-protein kinase, putative 0.014 0.0074 0.023
Loa Loa (eye worm) hypothetical protein 0.0212 0.0337 0.0333
Echinococcus multilocularis PAK box P21 Rho binding 0.017 0.0182 0.0199
Schistosoma mansoni serine/threonine protein kinase 0.0193 0.0269 0.0408
Brugia malayi casein kinase I 0.0227 0.0392 0.0379
Trichomonas vaginalis AGC family protein kinase 0.0196 0.0279 0.0542
Echinococcus multilocularis tyrosine protein kinase Fyn 0.0484 0.1324 0.1475
Brugia malayi Sex muscle abnormal protein 5 0.0195 0.0276 0.0263
Echinococcus multilocularis dual specificity 0.0179 0.0216 0.0236
Loa Loa (eye worm) hypothetical protein 0.0134 0.0053 0.0049
Echinococcus multilocularis ephrin type A receptor 4 A 0.0307 0.0681 0.0756
Echinococcus granulosus tyrosine kinase 0.0221 0.0369 0.0419
Plasmodium falciparum protein kinase, putative 0.0182 0.0229 0.0911
Schistosoma mansoni serine/threonine protein kinase 0.0176 0.0207 0.0309
Loa Loa (eye worm) TK/EPH protein kinase 0.0361 0.0877 0.0873
Echinococcus multilocularis tyrosine protein kinase shark 0.0434 0.1143 0.1273
Plasmodium vivax serine/threonine protein kinase KIN, putative 0.0176 0.0207 0.0819
Trypanosoma brucei Casein kinase II 0.028 0.0583 0.1236
Brugia malayi Protein kinase domain containing protein 0.0613 0.1792 0.1781
Echinococcus granulosus casein kinase i 0.0227 0.0392 0.0445
Leishmania major protein kinase A catalytic subunit 0.0196 0.0279 0.1076
Loa Loa (eye worm) CMGC/DYRK/HIPK protein kinase 0.0242 0.0446 0.0442
Loa Loa (eye worm) CMGC/GSK protein kinase 0.0368 0.0902 0.0899
Echinococcus granulosus twitchin 0.0338 0.0796 0.0908
Brugia malayi protein unc-22 0.0147 0.01 0.0087
Echinococcus multilocularis serine:threonine protein kinase PAK 3 0.0236 0.0425 0.047
Loa Loa (eye worm) camk/dcamkl protein kinase 0.0191 0.0258 0.0255
Entamoeba histolytica protein kinase, putative 0.0128 0.003 0.0065
Trichomonas vaginalis CMGC family protein kinase 0.028 0.0583 0.1203
Echinococcus multilocularis expressed protein 0.0123 0.0013 0.001
Echinococcus granulosus serine:threonine protein kinase Chk2 0.019 0.0255 0.0288
Echinococcus granulosus mitogen activated protein kinase 0.0229 0.0399 0.0454
Echinococcus multilocularis roundabout 2 0.0126 0.0026 0.0024
Loa Loa (eye worm) hypothetical protein 0.0233 0.0412 0.0408
Entamoeba histolytica protein kinase, putative 0.0222 0.0374 0.081
Brugia malayi Protein kinase domain containing protein 0.0349 0.0833 0.0821
Echinococcus granulosus nervana 2 0.0724 0.2197 0.2516
Trichomonas vaginalis 3-phosphoinositide dependent protein kinase-1, putative 0.0148 0.0104 0.0161
Brugia malayi hypothetical protein 0.0262 0.0517 0.0505
Trichomonas vaginalis mitogen-activated protein kinase kinase kinase 3, MAPKKK3, MEKK3, putative 0.014 0.0074 0.0095
Echinococcus granulosus calcium:calmodulin dependent protein kinase I 0.019 0.0255 0.0288
Schistosoma mansoni nck2/grb4 0.0195 0.0276 0.0419
Entamoeba histolytica PH domain containing protein kinase, putative 0.0251 0.0478 0.1034
Onchocerca volvulus 0.0197 0.0283 0.0502
Echinococcus granulosus Ribosomal protein S6 kinase beta 2 0.0613 0.1792 0.2051
Schistosoma mansoni serine/threonine protein kinase 0.0174 0.02 0.0298
Echinococcus multilocularis mitogen activated protein kinase 14 0.0462 0.1243 0.1384
Plasmodium falciparum calcium-dependent protein kinase 3 0.0188 0.0248 0.0989
Echinococcus multilocularis mitogen activated protein kinase 14 0.0462 0.1243 0.1384
Echinococcus multilocularis tyrosine protein kinase Fgr 0.0484 0.1324 0.1475
Brugia malayi Protein kinase domain containing protein 0.0429 0.1123 0.1111
Loa Loa (eye worm) SRC-1 0.0484 0.1324 0.1321
Entamoeba histolytica protein kinase domain containing protein 0.0242 0.0446 0.0966
Entamoeba histolytica protein kinase, putative 0.0348 0.083 0.1796
Schistosoma mansoni protein kinase 0.042 0.109 0.1717
Echinococcus multilocularis tyrosine protein kinase Fps85D 0.0524 0.1469 0.1637
Schistosoma mansoni serine/threonine protein kinase 0.0227 0.0392 0.0604
Loa Loa (eye worm) thyroid receptor interactor 0.0159 0.0146 0.0142
Echinococcus multilocularis epidermal growth factor receptor 0.1209 0.3957 0.4417
Brugia malayi Serine/threonine-protein kinase SULU 0.0262 0.0517 0.0505
Schistosoma mansoni serine/threonine protein kinase 0.0973 0.31 0.4921
Brugia malayi putative serine/threonine kinase SADA gamma 0.0176 0.0207 0.0194
Trypanosoma cruzi STE/STE20 serine/threonine-protein kinase, putative 0.0232 0.041 0.1498
Schistosoma mansoni serine/threonine protein kinase 0.0262 0.0517 0.0804
Trypanosoma cruzi casein kinase, putative 0.0227 0.0392 0.1431
Trichomonas vaginalis CAMK family protein kinase 0.0176 0.0207 0.0384
Echinococcus granulosus CDC7 cell division cycle 7 0.013 0.0037 0.0038
Echinococcus granulosus tyrosine protein kinase ABL1 0.0643 0.1901 0.2176
Loa Loa (eye worm) CAMK/TSSK protein kinase 0.0639 0.1886 0.1883
Echinococcus granulosus titin 0.0147 0.01 0.011
Brugia malayi Cam kinase protein 1 0.0188 0.0248 0.0236
Schistosoma mansoni serine/threonine protein kinase 0.0785 0.2419 0.3836
Plasmodium falciparum serine/threonine protein kinase 0.0123 0.0013 0.0031
Echinococcus multilocularis basic fibroblast growth factor receptor 1 A 0.072 0.2182 0.2434
Leishmania major protein kinase A catalytic subunit isoform 2 0.0196 0.0279 0.1076
Brugia malayi Protein kinase domain containing protein 0.0337 0.0792 0.078
Echinococcus multilocularis tyrosine protein kinase Src42A 0.0293 0.0629 0.0699
Loa Loa (eye worm) CMGC/MAPK/JNK protein kinase 0.0785 0.2419 0.2416
Leishmania major protein kinase, putative 0.0232 0.041 0.1604
Echinococcus multilocularis tyrosine kinase 0.0221 0.0369 0.0408
Loa Loa (eye worm) CMGC/CDK/CDK5 protein kinase 0.0337 0.0792 0.0788
Loa Loa (eye worm) hypothetical protein 0.046 0.1239 0.1235
Schistosoma mansoni serine/threonine protein kinase 0.014 0.0074 0.0097
Echinococcus granulosus guanine nucleotide exchange factor VAV2 0.0225 0.0382 0.0434
Schistosoma mansoni protein kinase 0.0327 0.0754 0.1181
Schistosoma mansoni serine/threonine protein kinase 0.0222 0.0374 0.0576
Brugia malayi p21/Cdc42/Rac1-activated kinase 0.014 0.0074 0.0061
Schistosoma mansoni serine/threonine protein kinase 0.0742 0.2262 0.3585
Echinococcus multilocularis 3 phosphoinositide dependent protein kinase 1 0.0222 0.0374 0.0414
Echinococcus multilocularis dual specificity 0.0179 0.0216 0.0236
Echinococcus multilocularis cyclin dependent kinase 1 0.0337 0.0792 0.088
Echinococcus multilocularis mitogen activated protein kinase 3 0.0229 0.0399 0.0442
Echinococcus multilocularis calcium:calmodulin dependent protein kinase type 0.0188 0.0248 0.0273
Trypanosoma brucei SNF1-related protein kinases, putative 0.0176 0.0207 0.042
Schistosoma mansoni tyrosine kinase 0.185 0.6285 1
Brugia malayi Protein kinase domain containing protein 0.0193 0.0269 0.0256
Onchocerca volvulus 0.0147 0.01 0.0129
Trypanosoma cruzi cAMP-dependent protein kinase catalytic subunit 3 0.0196 0.0279 0.1005
Entamoeba histolytica PH domain containing protein kinase, putative 0.0128 0.003 0.0065
Leishmania major serine/threonine-protein kinase a, putative 0.0128 0.003 0.0069
Schistosoma mansoni protein kinase 0.0429 0.1123 0.1769
Trypanosoma brucei casein kinase I, isoform 2 0.0227 0.0392 0.0822
Loa Loa (eye worm) camk/mapkapk/mnk protein kinase 0.0488 0.1337 0.1334
Trichomonas vaginalis AGC family protein kinase 0.0148 0.0104 0.0161
Schistosoma mansoni serine/threonine protein kinase 0.0196 0.0279 0.0424
Trichomonas vaginalis CMGC family protein kinase 0.028 0.0583 0.1203
Schistosoma mansoni protein kinase 0.0227 0.0392 0.0604
Brugia malayi Egg laying defective protein 4 0.0174 0.02 0.0187
Brugia malayi SRC-1 0.0484 0.1324 0.1313
Plasmodium vivax calcium-dependent protein kinase 3, putative 0.0188 0.0248 0.0989
Loa Loa (eye worm) AGC/PKA protein kinase 0.0196 0.0279 0.0275
Toxoplasma gondii cell-cycle-associated protein kinase GSK, putative 0.0368 0.0902 0.203
Echinococcus granulosus calcium:calmodulin dependent protein kinase type 0.0188 0.0248 0.0281
Trypanosoma cruzi mitogen activated protein kinase 2, putative 0.0229 0.0399 0.1459
Brugia malayi MAP kinase sur-1 0.0229 0.0399 0.0387
Leishmania major protein kinase, putative,dual-specificity protein kinase, putative 0.0179 0.0216 0.0819
Trypanosoma brucei dual specificity tyrosine-phosphorylation-regulated kinase 2, putative 0.0179 0.0216 0.0439
Echinococcus multilocularis casein kinase ii subunit alpha 0.028 0.0583 0.0647
Echinococcus multilocularis NCK adaptor protein 0.0197 0.0283 0.0312
Trichomonas vaginalis AGC family protein kinase 0.0222 0.0374 0.0749
Echinococcus granulosus cGMP dependent protein kinase 1 0.0174 0.02 0.0225
Loa Loa (eye worm) hypothetical protein 0.048 0.1311 0.1307
Trichomonas vaginalis AGC family protein kinase 0.042 0.109 0.2309
Brugia malayi Protein kinase domain containing protein 0.0639 0.1886 0.1876
Brugia malayi cAMP-dependent protein kinase catalytic subunit, putative 0.0196 0.0279 0.0266
Echinococcus multilocularis receptor type tyrosine protein phosphatase 0.0126 0.0026 0.0024
Echinococcus granulosus melanoma receptor tyrosine protein kinase 0.1209 0.3957 0.4534
Trypanosoma cruzi NIMA-related kinase, putative 0.0128 0.003 0.0065
Brugia malayi Immunoglobulin I-set domain containing protein 0.0126 0.0026 0.0013
Schistosoma mansoni serine/threonine protein kinase 0.0337 0.0792 0.1241
Echinococcus granulosus roundabout 2 0.0126 0.0026 0.0025
Entamoeba histolytica protein kinase, putative 0.1392 0.4621 1
Loa Loa (eye worm) TK/ROR protein kinase 0.0163 0.0158 0.0154
Schistosoma mansoni mitogen-activated protein kinase kinase kinase 3 mapkkk3 mekk3 0.0134 0.0053 0.0064
Loa Loa (eye worm) RhoGAP domain-containing protein 0.0225 0.0382 0.0378
Brugia malayi Temporarily assigned gene name protein 59 0.0397 0.101 0.0998
Echinococcus multilocularis Glutaredoxin protein 5 0.0724 0.2197 0.2451
Leishmania major protein kinase, putative 0.0182 0.0229 0.0874
Loa Loa (eye worm) TK/FER protein kinase 0.0221 0.0369 0.0366
Echinococcus granulosus tyrosine protein kinase Src42A 0.0293 0.0629 0.0718
Loa Loa (eye worm) CAMK/CAMKL/MELK protein kinase 0.0384 0.0961 0.0957
Echinococcus granulosus fibroblast growth factor receptor 4 0.072 0.2182 0.2499
Echinococcus granulosus calcium:calmodulin dependent protein kinase type 0.0188 0.0248 0.0281
Trichomonas vaginalis CAMK family protein kinase 0.0176 0.0207 0.0384
Entamoeba histolytica protein kinase, putative 0.0192 0.0263 0.0568
Echinococcus multilocularis serine:threonine protein kinase PAK 3 0.0236 0.0425 0.047
Brugia malayi phosphoinositide-dependent protein kinase I 0.0222 0.0374 0.0362
Echinococcus granulosus raf serine:threonine protein kinase 0.0223 0.0375 0.0426
Echinococcus multilocularis insulin growth factor 1 receptor beta 0.137 0.4542 0.5071
Echinococcus granulosus mitogen activated protein kinase kinase kinase 0.0207 0.0318 0.036
Plasmodium falciparum protein kinase 5 0.0337 0.0792 0.3201
Trichomonas vaginalis CAMK family protein kinase 0.0176 0.0207 0.0384
Trypanosoma cruzi cdc2-related kinase 3 0.0337 0.0792 0.2941
Echinococcus granulosus serine:threonine protein kinase mig 15 0.0254 0.0489 0.0556
Schistosoma mansoni serine/threonine protein kinase 0.0147 0.01 0.0139
Schistosoma mansoni tyrosine kinase 0.0323 0.0738 0.1156
Echinococcus multilocularis rac serine:threonine kinase 0.0852 0.2661 0.2969
Entamoeba histolytica hypothetical protein 0.0379 0.0944 0.2042
Onchocerca volvulus Serine\/threonine kinase homolog 0.0204 0.0307 0.055
Loa Loa (eye worm) AGC/PKC/IOTA protein kinase 0.046 0.1237 0.1234
Trypanosoma cruzi p21-activated kinase 3, putative 0.014 0.0074 0.023
Entamoeba histolytica protein kinase, putative 0.0289 0.0615 0.1331
Trichomonas vaginalis STE family protein kinase 0.0236 0.0425 0.086
Trypanosoma cruzi cdc2-related kinase 1 0.0337 0.0792 0.2941
Schistosoma mansoni tyrosine kinase 0.1349 0.4467 0.71
Toxoplasma gondii casein kinase I 0.0227 0.0392 0.0875
Loa Loa (eye worm) hypothetical protein 0.0213 0.034 0.0336
Loa Loa (eye worm) hypothetical protein 0.0442 0.1173 0.1169
Echinococcus granulosus 5' AMP activated protein kinase catalytic 0.0473 0.1285 0.147
Loa Loa (eye worm) casein kinase 0.018 0.022 0.0216
Trichomonas vaginalis CMGC family protein kinase 0.0368 0.0902 0.1899
Trichomonas vaginalis CMGC family protein kinase 0.013 0.0037 0.0015
Loa Loa (eye worm) TK/FAK protein kinase 0.0621 0.182 0.1817
Echinococcus granulosus serine/threonine protein kinase 0.0852 0.2661 0.3048
Echinococcus granulosus GTPase activating Rap:RanGAP domain 3 0.0134 0.0053 0.0057
Trichomonas vaginalis AGC family protein kinase 0.0148 0.0104 0.0161
Schistosoma mansoni tyrosine kinase 0.0206 0.0315 0.0482
Trichomonas vaginalis CMGC family protein kinase 0.013 0.0037 0.0015
Echinococcus granulosus tyrosine protein kinase shark 0.0434 0.1143 0.1307
Trypanosoma brucei protein kinase, putative 0.0229 0.0399 0.0838
Trichomonas vaginalis AGC family protein kinase 0.0613 0.1792 0.3837
Trichomonas vaginalis AGC family protein kinase 0.0391 0.0986 0.2081
Schistosoma mansoni atypical protein kinase C 0.1 0.3198 0.5078
Onchocerca volvulus Serine\/threonine kinase homolog 0.0804 0.2486 0.5003
Loa Loa (eye worm) STE/STE20/PAKB protein kinase 0.0686 0.2059 0.2056
Echinococcus multilocularis activin receptor type 0.0182 0.0229 0.0252
Trichomonas vaginalis CAMK family protein kinase 0.0804 0.2486 0.5349
Onchocerca volvulus 0.0427 0.1119 0.221
Echinococcus granulosus tyrosine protein kinase Fps85D 0.0524 0.1469 0.1681
Echinococcus granulosus tyrosine protein kinase Fyn 0.0484 0.1324 0.1515
Trypanosoma cruzi casein kinase, delta isoform, putative 0.0227 0.0392 0.1431
Giardia lamblia Kinase, AGC AKT 0.0332 0.0772 0.307
Plasmodium falciparum serine/threonine protein kinase, putative 0.042 0.109 0.4416
Echinococcus granulosus rho-associated protein kinase 1 0.0973 0.31 0.3552
Loa Loa (eye worm) TK protein kinase 0.0774 0.2376 0.2373
Brugia malayi Variant SH3 domain containing protein 0.017 0.0184 0.0172
Echinococcus multilocularis Immunoglobulin 0.0212 0.0337 0.0372
Entamoeba histolytica PH domain containing protein kinase, putative 0.0852 0.2661 0.5758
Brugia malayi protein-tyrosine kinase 0.04 0.102 0.1008
Loa Loa (eye worm) variant SH3 domain-containing protein 0.0195 0.0276 0.0272
Trichomonas vaginalis CMGC family protein kinase 0.028 0.0583 0.1203
Echinococcus granulosus neurotracting:lsamp:neurotrimin:obcam 0.0265 0.0527 0.06
Schistosoma mansoni serine/threonine protein kinase 0.0348 0.083 0.1303
Entamoeba histolytica protein kinase , putative 0.042 0.109 0.2359
Brugia malayi Protein kinase domain containing protein 0.0221 0.0369 0.0357
Trichomonas vaginalis CMGC family protein kinase 0.0179 0.0216 0.0404
Trypanosoma brucei cdc2-related kinase 1 0.0337 0.0792 0.169
Schistosoma mansoni serine/threonine protein kinase 0.029 0.0619 0.0967
Brugia malayi Serine/threonine-protein kinase Pim-3 0.0725 0.2198 0.2188
Trypanosoma brucei Vacuolar sorting protein 39 domain 1/Vacuolar sorting protein 39 domain 2, putative 0.0134 0.0053 0.0087
Echinococcus multilocularis insulin receptor 0.1349 0.4467 0.4987
Entamoeba histolytica protein kinase, putative 0.1337 0.4423 0.957
Brugia malayi Temporarily assigned gene name protein 59 0.0134 0.0053 0.004
Echinococcus granulosus mitogen activated protein kinase 3 0.0229 0.0399 0.0454
Brugia malayi Phorbol esters/diacylglycerol binding domain 0.0498 0.1377 0.1365
Trichomonas vaginalis CAMK family protein kinase 0.0323 0.0739 0.1544
Loa Loa (eye worm) hypothetical protein 0.0323 0.0739 0.0736
Loa Loa (eye worm) hypothetical protein 0.0168 0.0176 0.0172
Brugia malayi C1-like domain containing protein 0.0498 0.1377 0.1365
Loa Loa (eye worm) AGC/PDK1 protein kinase 0.0222 0.0374 0.037
Echinococcus granulosus tyrosine protein kinase Fyn 0.0484 0.1324 0.1515
Brugia malayi Immunoglobulin I-set domain containing protein 0.0233 0.0412 0.04
Echinococcus granulosus glycogen synthase kinase 3 beta 0.0368 0.0902 0.103
Brugia malayi Protein kinase domain containing protein 0.0253 0.0485 0.0472
Echinococcus granulosus Glutaredoxin protein 5 0.0724 0.2197 0.2516
Loa Loa (eye worm) hypothetical protein 0.0235 0.0421 0.0417
Echinococcus multilocularis ribosomal protein S6 kinase alpha 3 0.0872 0.2733 0.3049
Echinococcus granulosus dual specificity protein kinase clk2 0.0193 0.0269 0.0304
Schistosoma mansoni serine/threonine protein kinase 0.0176 0.0207 0.0309
Loa Loa (eye worm) hypothetical protein 0.0318 0.0721 0.0717
Trypanosoma brucei cAMP-dependent protein kinase catalytic subunit 1 0.0196 0.0279 0.0578
Trypanosoma cruzi STE/STE11 serine/threonine-protein kinase, putative 0.0182 0.0229 0.0816
Echinococcus granulosus dual specificity testis-specific protein kinase 0.0661 0.1969 0.2254
Echinococcus granulosus Immunoglobulin 0.0212 0.0337 0.0382
Schistosoma mansoni serine/threonine protein kinase 0.0552 0.1571 0.2484
Echinococcus multilocularis p21 activated protein kinase 1 Dpak1 0.0236 0.0425 0.047
Echinococcus granulosus Serine/threonine-protein kinase Genghis Khan 0.0469 0.1271 0.1453
Brugia malayi Protein kinase domain containing protein 0.1349 0.4467 0.4459
Trypanosoma cruzi Serine/threonine-protein kinase NEK21, putative 0.0128 0.003 0.0065
Brugia malayi serine/threonine kinase 12 0.042 0.109 0.1079
Schistosoma mansoni serine/threonine protein kinase 0.0469 0.1271 0.2005
Echinococcus granulosus serine:threonine protein kinase N2 0.0129 0.0036 0.0037
Echinococcus granulosus protein kinase c iota type 0.0981 0.313 0.3586
Echinococcus granulosus serine:threonine protein kinase MARK2 0.0552 0.1571 0.1798
Brugia malayi Protein kinase domain containing protein 0.0639 0.1886 0.1876
Entamoeba histolytica PH domain containing protein kinase, putative 0.0251 0.0478 0.1034
Trypanosoma cruzi casein kinase, putative 0.0227 0.0392 0.1431
Echinococcus multilocularis roundabout 2 0.0126 0.0026 0.0024
Echinococcus granulosus dual specificity 0.0179 0.0216 0.0243
Echinococcus granulosus 5'partial|cyclin dependent kinase 1 0.0337 0.0792 0.0904
Loa Loa (eye worm) hypothetical protein 0.0312 0.0701 0.0698
Trypanosoma cruzi casein kinase, putative 0.0227 0.0392 0.1431
Loa Loa (eye worm) AGC/PKA protein kinase 0.0196 0.0279 0.0275
Entamoeba histolytica protein kinase, putative 0.0348 0.083 0.1796
Loa Loa (eye worm) hypothetical protein 0.0229 0.0398 0.0394
Trypanosoma cruzi CMGC/DYRK protein kinase, putative 0.0348 0.083 0.3086
Schistosoma mansoni tyrosine kinase 0.1099 0.3559 0.5653
Loa Loa (eye worm) TK/FER protein kinase 0.0221 0.0369 0.0366
Trichomonas vaginalis AGC family protein kinase 0.0148 0.0104 0.0161
Loa Loa (eye worm) variant SH3 domain-containing protein 0.017 0.0184 0.0181
Trichomonas vaginalis AGC family protein kinase 0.0633 0.1866 0.3999
Schistosoma mansoni tyrosine kinase 0.0305 0.0674 0.1053
Echinococcus multilocularis arf GAP with SH3 domain, ANK repeat and PH 0.0139 0.007 0.0073
Trichomonas vaginalis AGC family protein kinase 0.1392 0.4621 1
Toxoplasma gondii protein kinase domain-containing protein 0.0128 0.003 0.0056
Loa Loa (eye worm) CK1/CK1/CK1-A protein kinase 0.0227 0.0392 0.0388
Brugia malayi Fibronectin type III domain containing protein 0.0233 0.0412 0.04
Trichomonas vaginalis AGC family protein kinase 0.0148 0.0104 0.0161
Trypanosoma cruzi cAMP-dependent protein kinase catalytic subunit 2 0.0196 0.0279 0.1005
Loa Loa (eye worm) STE/STE20/PAKA protein kinase 0.014 0.0074 0.007
Echinococcus multilocularis serine:threonine protein kinase 0.0323 0.0739 0.0822
Schistosoma mansoni serine/threonine-protein kinase 0.0852 0.2661 0.4221
Echinococcus multilocularis Protein kinase C, brain isozyme 0.0852 0.266 0.2968
Brugia malayi Protein kinase domain containing protein 0.0765 0.2344 0.2334
Trichomonas vaginalis CK1 family protein kinase 0.0227 0.0392 0.0788
Toxoplasma gondii protein kinase G AGC kinase family member PKG 0.0174 0.02 0.044
Giardia lamblia Kinase, CMGC DYRK 0.0179 0.0216 0.0819
Trichomonas vaginalis CAMK family protein kinase 0.0176 0.0207 0.0384
Brugia malayi p70 ribosomal S6 kinase beta 0.1337 0.4423 0.4415
Brugia malayi Variant SH3 domain containing protein 0.0225 0.0382 0.0369
Echinococcus granulosus mitogen activated protein kinase kinase kinase 0.0429 0.1123 0.1284
Schistosoma mansoni protein kinase 0.017 0.0182 0.027
Entamoeba histolytica protein kinase, putative 0.0128 0.003 0.0065
Entamoeba histolytica protein kinase, putative 0.0123 0.0013 0.0028
Onchocerca volvulus 0.0221 0.0369 0.0679
Toxoplasma gondii protein kinase, cAMP-dependent, catalytic chain 0.0196 0.0279 0.062
Echinococcus granulosus enhancer of mRNA decapping protein 4 0.0123 0.0014 0.0012
Echinococcus granulosus protein kinase shaggy 0.0368 0.0902 0.103
Trichomonas vaginalis serine/threonine-protein kinase sgk, putative 0.056 0.1601 0.3422
Echinococcus multilocularis calcium:calmodulin dependent protein kinase type 0.0188 0.0248 0.0273
Echinococcus granulosus NDR protein kinase 0.0613 0.1792 0.2051
Loa Loa (eye worm) CAMK/CAMKL/MARK protein kinase 0.0323 0.0739 0.0736
Trichomonas vaginalis conserved hypothetical protein 0.0163 0.016 0.0283
Loa Loa (eye worm) hypothetical protein 0.0639 0.1886 0.1883
Schistosoma mansoni protein kinase C mu 0.0498 0.1377 0.2174
Echinococcus multilocularis guanine nucleotide exchange factor VAV2 0.0225 0.0382 0.0422
Entamoeba histolytica hypothetical protein 0.0348 0.083 0.1796
Onchocerca volvulus 0.0973 0.31 0.6257
Echinococcus multilocularis cAMP dependent protein kinase catalytic subunit 0.0196 0.0279 0.0308
Loa Loa (eye worm) CAMK/PIM protein kinase 0.0725 0.2198 0.2195
Echinococcus granulosus receptor type tyrosine protein phosphatase 0.0126 0.0026 0.0025
Giardia lamblia Kinase, AGC PKA 0.0196 0.0279 0.1076
Entamoeba histolytica PH domain containing protein kinase, putative 0.0128 0.003 0.0065
Echinococcus granulosus cyclin dependent kinase 5 0.0337 0.0792 0.0904
Echinococcus granulosus tyrosine protein kinase Src42A 0.0484 0.1324 0.1515
Schistosoma mansoni hypothetical protein 0.0229 0.0398 0.0614
Schistosoma mansoni protein kinase 0.0182 0.0229 0.0345
Giardia lamblia Kinase, NEK 0.0391 0.0986 0.3933
Echinococcus multilocularis maternal embryonic leucine zipper kinase 0.0155 0.0129 0.014
Echinococcus granulosus proto oncogene tyrosine protein kinase LCK 0.0484 0.1324 0.1515
Echinococcus multilocularis twitchin 0.0126 0.0025 0.0024
Echinococcus granulosus 3-phosphoinositide-dependent protein kinase 1 0.0222 0.0374 0.0425
Schistosoma mansoni proto-oncogene tyrosine-protein kinase abl1 0.0195 0.0276 0.0419
Schistosoma mansoni protein kinase 0.0236 0.0425 0.0657
Echinococcus multilocularis phosphorylase kinase gamma subunit 0.0204 0.0307 0.0338
Echinococcus multilocularis protein kinase shaggy 0.0368 0.0902 0.1004
Schistosoma mansoni growth factor receptor-bound protein 0.0195 0.0276 0.0419
Plasmodium falciparum protein serine/threonine kinase-1 0.0193 0.0269 0.1071
Loa Loa (eye worm) CMGC/CK2 protein kinase 0.028 0.0583 0.0579
Loa Loa (eye worm) AGC/AKT protein kinase 0.1392 0.4621 0.4619
Trichomonas vaginalis AGC family protein kinase 0.042 0.109 0.2309
Schistosoma mansoni protein kinase 0.0661 0.1969 0.3118
Echinococcus granulosus ribosomal protein S6 kinase alpha 3 0.0872 0.2733 0.3131
Schistosoma mansoni serine/threonine protein kinase 0.0725 0.2198 0.3484
Echinococcus multilocularis protein kinase c epsilon type 0.073 0.2216 0.2472
Schistosoma mansoni protein kinase 0.0661 0.1969 0.3118
Loa Loa (eye worm) CAMK protein kinase 0.0147 0.01 0.0096
Brugia malayi Immunoglobulin I-set domain containing protein 0.0147 0.01 0.0087
Trypanosoma cruzi Serine/threonine-protein kinase NEK17, putative 0.0128 0.003 0.0065
Loa Loa (eye worm) CAMK/CAMK2 protein kinase 0.0188 0.0248 0.0245
Loa Loa (eye worm) CAMK/TSSK protein kinase 0.0639 0.1886 0.1883
Echinococcus multilocularis mitogen activated protein kinase kinase kinase 0.0207 0.0318 0.0351
Leishmania major mitogen activated protein kinase 4, putative;with=GeneDB:LmxM19.1440 0.0229 0.0399 0.1562
Echinococcus granulosus protein tyrosine kinase 0.0615 0.1799 0.2059
Entamoeba histolytica casein kinase 1, putative 0.0227 0.0392 0.0848
Brugia malayi Tyrosine-protein kinase abl-1 0.026 0.0512 0.05
Schistosoma mansoni hypothetical protein 0.0229 0.0398 0.0614
Loa Loa (eye worm) hypothetical protein 0.0195 0.0276 0.0272
Trypanosoma brucei Serine/threonine-protein kinase NEK21, putative 0.0128 0.003 0.0037
Trichomonas vaginalis AGC family protein kinase 0.0148 0.0104 0.0161
Plasmodium falciparum casein kinase 2, alpha subunit 0.028 0.0583 0.2349
Loa Loa (eye worm) hypothetical protein 0.0212 0.0337 0.0333
Trichomonas vaginalis CAMK family protein kinase 0.0176 0.0207 0.0384
Schistosoma mansoni cell adhesion molecule 0.0126 0.0026 0.002
Loa Loa (eye worm) CMGC/CLK protein kinase 0.0193 0.0269 0.0265
Trichomonas vaginalis AGC family protein kinase 0.0148 0.0104 0.0161
Trypanosoma cruzi SNF1-related protein kinases, putative 0.0176 0.0207 0.0731
Loa Loa (eye worm) hypothetical protein 0.0275 0.0565 0.0562
Schistosoma mansoni serine/threonine protein kinase 0.1186 0.3872 0.6153
Loa Loa (eye worm) CAMK/PKD protein kinase 0.0385 0.0966 0.0963
Loa Loa (eye worm) hypothetical protein 0.0254 0.0489 0.0485
Echinococcus granulosus tyrosine protein kinase Lyn 0.0557 0.1589 0.1818
Toxoplasma gondii cell-cycle-associated protein kinase CDK, putative 0.0337 0.0792 0.178
Loa Loa (eye worm) CAMK/PKD protein kinase 0.0498 0.1377 0.1373
Entamoeba histolytica protein kinase 2, putative 0.0797 0.2462 0.5327
Echinococcus multilocularis CDC7 cell division cycle 7 0.013 0.0037 0.0037
Echinococcus multilocularis cyclin dependent kinase 0.0337 0.0792 0.088
Loa Loa (eye worm) AGC/RSK/P70 protein kinase 0.1337 0.4423 0.442
Echinococcus granulosus basic fibroblast growth factor receptor 1 A 0.072 0.2182 0.2499
Echinococcus granulosus growth factor receptor bound protein 2 0.0197 0.0283 0.032
Schistosoma mansoni serine/threonine protein kinase 0.0176 0.0207 0.0309
Brugia malayi Pleckstrin Homology Domain 0.0168 0.0176 0.0163
Trichomonas vaginalis CAMK family protein kinase 0.0384 0.0961 0.2026
Echinococcus multilocularis casein kinase I gamma 0.0253 0.0485 0.0537
Plasmodium vivax serine/threonine kinase-1, putative 0.0193 0.0269 0.1071
Schistosoma mansoni serine/threonine protein kinase 0.0174 0.02 0.0298
Echinococcus multilocularis serine:threonine protein kinase Chk2 0.019 0.0255 0.0281
Brugia malayi casein kinase 1, delta 0.0227 0.0392 0.0379
Trichomonas vaginalis AGC family protein kinase 0.1392 0.4621 1
Echinococcus multilocularis serine:threonine protein kinase 0.0323 0.0739 0.0822
Schistosoma mansoni serine/threonine protein kinase 0.0188 0.0248 0.0375
Echinococcus granulosus RNA directed DNA polymerase 0.0122 0.001 0.0007
Trypanosoma cruzi rac serine-threonine kinase, putative 0.0797 0.2462 0.9249
Schistosoma mansoni vam6/vps39 related 0.0134 0.0053 0.0064
Brugia malayi Protein kinase domain containing protein 0.0222 0.0374 0.0362
Schistosoma mansoni tyrosine kinase 0.0531 0.1496 0.2364
Echinococcus multilocularis casein kinase I delta 0.0227 0.0392 0.0434
Echinococcus granulosus Serine:threonine protein kinase PLK4 0.0418 0.1083 0.1238
Schistosoma mansoni tyrosine kinase 0.0767 0.2352 0.3729
Entamoeba histolytica serine/threonine-protein kinase 3, putative 0.0232 0.041 0.0887
Trichomonas vaginalis CMGC family protein kinase 0.028 0.0583 0.1203
Brugia malayi serine/threonine-protein kinase PAK 7 0.0686 0.2059 0.2049
Loa Loa (eye worm) hypothetical protein 0.0366 0.0897 0.0894
Echinococcus multilocularis tyrosine protein kinase Abl 0.0466 0.1259 0.1403
Entamoeba histolytica protein kinase, putative 0.0368 0.0902 0.1952
Trichomonas vaginalis AGC family protein kinase 0.0148 0.0104 0.0161
Entamoeba histolytica protein kinase domain containing protein 0.042 0.109 0.2359
Leishmania major protein kinase, putative 0.0128 0.003 0.0069
Echinococcus granulosus tyrosine protein kinase transmembrane receptor 0.0163 0.0158 0.0177
Trichomonas vaginalis ribosomal protein S6 kinase, 90kD, polypeptide, putative 0.0148 0.0104 0.0161
Entamoeba histolytica casein kinase, putative 0.0227 0.0392 0.0848
Schistosoma mansoni serine/threonine-protein kinase 0.0852 0.2661 0.4221
Echinococcus granulosus protein kinase 0.0193 0.0267 0.0302
Loa Loa (eye worm) TK/INSR protein kinase 0.1349 0.4467 0.4465
Plasmodium vivax protein kinase Crk2 0.0337 0.0792 0.3201
Brugia malayi Protein kinase domain containing protein 0.1392 0.4621 0.4614
Echinococcus multilocularis c Jun NH2 terminal kinase 0.0785 0.2419 0.2699
Loa Loa (eye worm) AGC/NDR protein kinase 0.0613 0.1792 0.1789
Brugia malayi Protein kinase domain containing protein 0.0725 0.2198 0.2188
Echinococcus granulosus insulin growth factor 1 receptor beta 0.137 0.4542 0.5206
Trichomonas vaginalis CAMK family protein kinase 0.0176 0.0207 0.0384
Trypanosoma cruzi mitogen activated protein kinase 4, putative 0.0229 0.0399 0.1459
Loa Loa (eye worm) immunoglobulin I-set domain-containing protein 0.0126 0.0026 0.0022
Trypanosoma brucei protein kinase, putative 0.0182 0.0229 0.0469
Entamoeba histolytica protein kinase, putative 0.0236 0.0425 0.0919
Trypanosoma cruzi glycogen synthase kinase 3, putative 0.0368 0.0902 0.3358
Plasmodium vivax unspecified product 0.028 0.0583 0.2349
Onchocerca volvulus 0.048 0.1311 0.2602
Echinococcus granulosus tyrosine protein kinase 0.0349 0.0833 0.0951
Trichomonas vaginalis CAMK family protein kinase 0.0804 0.2486 0.5349
Trichomonas vaginalis STE family protein kinase 0.017 0.0182 0.0331
Giardia lamblia Kinase, CK1 Casein kinase 0.0227 0.0392 0.1532
Leishmania major protein kinase, putative,serine/threonine protein kinase, putative 0.0128 0.003 0.0069
Loa Loa (eye worm) TK/ALK protein kinase 0.0346 0.0821 0.0818
Brugia malayi Protein kinase domain containing protein 0.0232 0.0411 0.0398
Schistosoma mansoni serine/threonine protein kinase 0.0193 0.0269 0.0408
Trichomonas vaginalis CMGC family protein kinase 0.0179 0.0216 0.0404
Trypanosoma cruzi serine/threonine-protein kinase NRKB, putative 0.0128 0.003 0.0065
Trypanosoma cruzi Serine/threonine-protein kinase NEK21, putative 0.0128 0.003 0.0065
Echinococcus multilocularis Ribosomal protein S6 kinase beta 2 0.0613 0.1792 0.1998
Echinococcus granulosus casein kinase I delta 0.0227 0.0392 0.0445
Echinococcus multilocularis dual specificity testis specific protein kinase 0.0661 0.1969 0.2195
Toxoplasma gondii calcium-dependent protein kinase CDPK3 0.0188 0.0248 0.055
Brugia malayi Homeodomain interacting protein kinase protein 1 0.0242 0.0446 0.0434
Echinococcus granulosus casein kinase I gamma 0.0253 0.0485 0.0552
Schistosoma mansoni serine/threonine protein kinase 0.0176 0.0207 0.0309
Echinococcus multilocularis 0.0193 0.0267 0.0294
Toxoplasma gondii cell-cycle-associated protein kinase DYRK2, putative 0.0179 0.0216 0.0476
Brugia malayi Variant SH3 domain containing protein 0.0195 0.0276 0.0263
Schistosoma mansoni serine/threonine protein kinase 0.0126 0.0025 0.0019
Echinococcus granulosus casein kinase I alpha 0.0227 0.0392 0.0445
Leishmania major rac serine-threonine kinase, putative,protein kinase, putative 0.0387 0.0971 0.3874
Schistosoma mansoni tyrosine kinase 0.1209 0.3957 0.6287
Echinococcus multilocularis contactin neuroglian septate junction protein 0.0126 0.0026 0.0024
Schistosoma mansoni kinase 0.0861 0.2693 0.4272
Loa Loa (eye worm) hypothetical protein 0.0414 0.1071 0.1067
Loa Loa (eye worm) hypothetical protein 0.0425 0.1112 0.1108
Echinococcus multilocularis tyrosine protein kinase Blk 0.04 0.102 0.1136
Loa Loa (eye worm) TK/FER protein kinase 0.0221 0.0369 0.0366
Echinococcus multilocularis sodium:potassium dependent atpase beta subunit 0.0724 0.2197 0.2451
Loa Loa (eye worm) CK1/CK1/CK1-D protein kinase 0.0227 0.0392 0.0388
Trichomonas vaginalis CAMK family protein kinase 0.0361 0.0876 0.1843
Brugia malayi Furin-like cysteine rich region family protein 0.185 0.6285 0.628
Trichomonas vaginalis AGC family protein kinase 0.0148 0.0104 0.0161
Schistosoma mansoni protein kinase 0.052 0.1456 0.23
Trypanosoma brucei serine/threonine-protein kinase NRKB, putative 0.0128 0.003 0.0037
Loa Loa (eye worm) PLK/PLK1 protein kinase 0.0804 0.2486 0.2483
Echinococcus granulosus serine:threonine kinase SAD 1 0.0176 0.0207 0.0233
Schistosoma mansoni serine/threonine protein kinase 0.0179 0.0216 0.0323
Echinococcus multilocularis cyclin dependent kinase 1 0.0337 0.0792 0.088
Brugia malayi Immunoglobulin I-set domain containing protein 0.0126 0.0026 0.0013
Echinococcus multilocularis proto oncogene serine:threonine protein kinase 0.0725 0.2198 0.2452
Loa Loa (eye worm) AUR protein kinase 0.042 0.109 0.1087
Trichomonas vaginalis CMGC family protein kinase 0.0193 0.0269 0.0519
Loa Loa (eye worm) TK/EGFR protein kinase 0.185 0.6285 0.6284
Onchocerca volvulus 0.0368 0.0902 0.1767
Echinococcus multilocularis telomerase reverse transcriptase subunit 0.0122 0.001 0.0007
Trichomonas vaginalis STE family protein kinase 0.0232 0.041 0.0827
Echinococcus granulosus expressed protein 0.0123 0.0013 0.0011
Trichomonas vaginalis AGC family protein kinase 0.0148 0.0104 0.0161
Trypanosoma cruzi serine/threonine protein kinase, putative 0.0128 0.003 0.0065
Trichomonas vaginalis CMGC family protein kinase 0.0337 0.0792 0.1659
Entamoeba histolytica serine/threonine- protein kinase 6, putative 0.042 0.109 0.2359
Plasmodium vivax rac-beta serine/threonine protein kinase, putative 0.0797 0.2462 1
Leishmania major protein kinase, putative,polo-like protein kinase, putative 0.0804 0.2486 1
Trichomonas vaginalis STE family protein kinase 0.0236 0.0425 0.086
Brugia malayi Immunoglobulin I-set domain containing protein 0.1689 0.5699 0.5694
Loa Loa (eye worm) AUR protein kinase 0.042 0.109 0.1087
Echinococcus multilocularis casein kinase i 0.0227 0.0392 0.0434
Trypanosoma cruzi CMGC/DYRK protein kinase, putative 0.0348 0.083 0.3086
Echinococcus multilocularis tyrosine protein kinase Btk29A 0.0849 0.2649 0.2956
Echinococcus multilocularis roundabout 2 0.0339 0.0796 0.0885
Loa Loa (eye worm) TK protein kinase 0.0349 0.0833 0.083
Loa Loa (eye worm) CAMK/PHK protein kinase 0.0204 0.0307 0.0303
Echinococcus granulosus tyrosine kinase|tyrosine protein kinase Fyn 0.04 0.102 0.1166
Loa Loa (eye worm) hypothetical protein 0.0134 0.0053 0.0049
Plasmodium falciparum calcium-dependent protein kinase 7 0.0128 0.003 0.0101
Schistosoma mansoni ephrin receptor 0.0307 0.0681 0.1064
Trichomonas vaginalis CAMK family protein kinase 0.0176 0.0207 0.0384
Echinococcus granulosus tyrosine protein kinase Srms 0.0628 0.1847 0.2114
Entamoeba histolytica protein kinase, putative 0.0179 0.0216 0.0466
Schistosoma mansoni serine/threonine protein kinase 0.0852 0.266 0.422
Echinococcus multilocularis Immunoglobulin 0.0212 0.0337 0.0372
Echinococcus granulosus homeodomain interacting protein kinase 3 0.0242 0.0446 0.0507
Loa Loa (eye worm) AUR protein kinase 0.042 0.109 0.1087
Trichomonas vaginalis CMGC family protein kinase 0.0337 0.0792 0.1659
Trichomonas vaginalis CAMK family protein kinase 0.0176 0.0207 0.0384
Trypanosoma brucei 5'-AMP-activated protein kinase catalytic subunit alpha, putative 0.0176 0.0207 0.042
Entamoeba histolytica serine/threonine protein kinase, putative 0.0176 0.0207 0.0447
Leishmania major mitogen-activated protein kinase 3, putative,map kinase 3, putative 0.0462 0.1243 0.4972
Echinococcus multilocularis casein kinase I alpha 0.0227 0.0392 0.0434
Echinococcus granulosus tyrosine protein kinase Blk 0.04 0.102 0.1166
Brugia malayi Protein kinase domain containing protein 0.0221 0.0369 0.0357
Brugia malayi Calcium/calmodulin-dependent protein kinase type II alpha chain 0.0332 0.0774 0.0762
Echinococcus granulosus serine:threonine protein kinase N2 0.0742 0.2262 0.259
Echinococcus granulosus sodium:potassium dependent atpase beta subunit 0.0724 0.2197 0.2516
Loa Loa (eye worm) TK/FER protein kinase 0.0221 0.0369 0.0366
Toxoplasma gondii calcium dependent protein kinase CDPK7 0.0128 0.003 0.0056
Echinococcus granulosus casein kinase ii subunit alpha 0.028 0.0583 0.0664
Brugia malayi cell division control protein 2 homolog 0.0337 0.0792 0.078
Echinococcus granulosus defective proboscis extension response 0.0212 0.0337 0.0382
Brugia malayi probable protein kinase 0.0327 0.0754 0.0742
Echinococcus multilocularis serine:threonine kinase SAD 1 0.0176 0.0207 0.0227
Entamoeba histolytica protein kinase, putative 0.017 0.0182 0.0394
Plasmodium falciparum RAC-beta serine/threonine protein kinase 0.0797 0.2462 1
Entamoeba histolytica protein kinase domain containing protein 0.0179 0.0216 0.0466
Echinococcus multilocularis serine threonine protein kinase 0.0739 0.225 0.2509
Schistosoma mansoni tyrosine kinase 0.1209 0.3957 0.6287
Schistosoma mansoni serine/threonine protein kinase 0.019 0.0255 0.0386
Giardia lamblia Kinase, CMGC CLK 0.0193 0.0269 0.1034
Loa Loa (eye worm) hypothetical protein 0.0233 0.0412 0.0408
Echinococcus granulosus cGMP dependent protein kinase 1 0.0174 0.02 0.0225
Giardia lamblia Kinase, CMGC CK2 0.028 0.0583 0.2303
Brugia malayi hypothetical protein 0.0134 0.0053 0.004
Brugia malayi Immunoglobulin I-set domain containing protein 0.0126 0.0026 0.0013
Trichomonas vaginalis AGC family protein kinase 0.0688 0.2065 0.4432
Brugia malayi Protein kinase domain containing protein 0.0323 0.0739 0.0727
Echinococcus granulosus nervana 2 0.0724 0.2197 0.2516
Echinococcus multilocularis serine:threonine protein kinase TAO1 0.0262 0.0517 0.0574
Echinococcus granulosus calcium:calmodulin dependent protein kinase type 1 0.0188 0.0248 0.0281
Trypanosoma brucei STE20-like serine/threonine-protein kinase 1, putative 0.0232 0.041 0.0861
Giardia lamblia Kinase, CAMK CAMKL 0.0176 0.0207 0.0783
Schistosoma mansoni protein kinase 0.0236 0.0425 0.0657
Loa Loa (eye worm) hypothetical protein 0.0188 0.0248 0.0245
Brugia malayi Doublecortin family protein 0.0191 0.0258 0.0246
Echinococcus granulosus mitogen activated protein kinase 11 0.0462 0.1243 0.1421
Trichomonas vaginalis AGC family protein kinase 0.0148 0.0104 0.0161
Echinococcus granulosus activin receptor type 0.0182 0.0229 0.0258
Entamoeba histolytica SH2-protein kinase domain containing protein 0.0221 0.0369 0.0799
Echinococcus multilocularis serine:threonine protein kinase PAK 4 0.059 0.1708 0.1904
Echinococcus granulosus STE20 serine:threonine protein kinase 0.0533 0.1503 0.172
Toxoplasma gondii NIMA-related protein kinase NIMA1 0.0391 0.0986 0.2219
Echinococcus granulosus cGMP dependent protein kinase 0.0174 0.02 0.0225
Echinococcus multilocularis MAP kinase activated protein kinase 2 0.1186 0.3872 0.4323
Trypanosoma cruzi cdc2-related kinase 1 0.0337 0.0792 0.2941
Entamoeba histolytica protein kinase, putative 0.019 0.0255 0.0552
Schistosoma mansoni protein kinase 0.052 0.1456 0.23
Echinococcus multilocularis N chimaerin 0.0225 0.0382 0.0422
Schistosoma mansoni vav2 0.0279 0.0581 0.0905
Toxoplasma gondii CMGC kinase, CK2 family 0.028 0.0583 0.1307
Brugia malayi ephrin receptor 1 precursor 0.0202 0.0302 0.0289
Onchocerca volvulus 0.0227 0.0392 0.0725
Brugia malayi Fes/CIP4 homology domain containing protein 0.0159 0.0146 0.0133
Echinococcus granulosus mitogen activated protein kinase 14 0.0462 0.1243 0.1421
Trypanosoma cruzi kinetoplastid kinetochore protein 10, putative 0.0193 0.0269 0.0965
Onchocerca volvulus 0.0154 0.0127 0.0184
Schistosoma mansoni serine/threonine protein kinase 0.014 0.0074 0.0097
Trypanosoma cruzi STE/STE20 serine/threonine-protein kinase, putative 0.0232 0.041 0.1498
Trypanosoma cruzi casein kinase II, putative 0.028 0.0583 0.2151
Echinococcus multilocularis cAMP dependent protein kinase catalytic subunit 0.0196 0.0279 0.0308
Echinococcus multilocularis serine:threonine protein kinase MARK2 0.0552 0.1571 0.1751
Brugia malayi Casein kinase II, alpha chain 0.028 0.0583 0.057
Schistosoma mansoni ephrin receptor 0.013 0.0039 0.0042
Loa Loa (eye worm) STE/STE20/KHS protein kinase 0.0429 0.1123 0.1119
Schistosoma mansoni protein kinase 0.028 0.0583 0.0908
Echinococcus granulosus aurora kinase A 0.042 0.109 0.1246
Brugia malayi ribosomal protein S6 kinase alpha 3 0.0332 0.0772 0.076
Onchocerca volvulus 0.1315 0.4341 0.8791
Trichomonas vaginalis STE family protein kinase 0.0236 0.0425 0.086
Trichomonas vaginalis CMGC family protein kinase 0.028 0.0583 0.1203
Echinococcus multilocularis casein kinase I alpha 0.0227 0.0392 0.0434
Loa Loa (eye worm) CMGC/CDK/CDC2 protein kinase 0.0337 0.0792 0.0788
Echinococcus granulosus serine:threonine protein kinase 3 0.0763 0.2336 0.2675
Echinococcus granulosus NCK adaptor protein 0.0195 0.0276 0.0312
Loa Loa (eye worm) TK/FER protein kinase 0.0221 0.0369 0.0366
Trypanosoma cruzi rac serine-threonine kinase, putative 0.0128 0.003 0.0065
Entamoeba histolytica casein kinase, putative 0.028 0.0583 0.1261
Schistosoma mansoni hypothetical protein 0.0134 0.0053 0.0064
Onchocerca volvulus 0.0221 0.0369 0.0679
Schistosoma mansoni serine/threonine kinase 0.0384 0.0961 0.1511
Trypanosoma brucei cAMP-dependent protein kinase catalytic subunit 2 0.0196 0.0279 0.0578
Brugia malayi RhoGAP domain containing protein 0.0225 0.0382 0.0369
Schistosoma mansoni growth factor receptor-bound protein 0.0197 0.0283 0.043
Trichomonas vaginalis CAMK family protein kinase 0.0176 0.0207 0.0384
Trichomonas vaginalis CMGC family protein kinase 0.0179 0.0216 0.0404
Trypanosoma cruzi cAMP-dependent protein kinase catalytic subunit 1 0.0196 0.0279 0.1005
Schistosoma mansoni serine/threonine protein kinase 0.0516 0.144 0.2276
Schistosoma mansoni tyrosine kinase 0.0305 0.0674 0.1053
Echinococcus granulosus cyclin dependent kinase 0.0337 0.0792 0.0904
Trichomonas vaginalis CMGC family protein kinase 0.028 0.0583 0.1203
Schistosoma mansoni rap gtpase-activating protein 0.0134 0.0053 0.0064
Echinococcus multilocularis serine:threonine protein kinase N2 0.0742 0.2262 0.2523
Loa Loa (eye worm) hypothetical protein 0.0427 0.1119 0.1116
Echinococcus multilocularis death associated protein kinase 1 0.2585 0.8953 1
Schistosoma mansoni mitogen-activated protein kinase kinase kinase 3 mapkkk3 mekk3 0.0134 0.0053 0.0064
Echinococcus multilocularis cAMP dependent protein kinase catalytic subunit 0.0196 0.0279 0.0308
Onchocerca volvulus Tyrosine kinase homolog 0.1477 0.4932 1
Trichomonas vaginalis AGC family protein kinase 0.0148 0.0104 0.0161
Echinococcus granulosus serine:threonine protein kinase 0.0323 0.0739 0.0844
Schistosoma mansoni serine/threonine protein kinase 0.0337 0.0792 0.1241
Entamoeba histolytica protein kinase, putative 0.0188 0.0248 0.0538
Schistosoma mansoni tyrosine kinase 0.0615 0.1799 0.2847
Schistosoma mansoni glycogen synthase kinase 3-related (gsk3) (cmgc group III) 0.0368 0.0902 0.1417
Echinococcus multilocularis serine:threonine protein kinase 38 0.0613 0.1792 0.1998
Schistosoma mansoni nephrin 0.0286 0.0606 0.0945
Schistosoma mansoni ste20-related kinase 0.0603 0.1757 0.2781
Brugia malayi Hr1 repeat family protein 0.0742 0.2262 0.2252
Loa Loa (eye worm) hypothetical protein 0.0134 0.0053 0.0049
Brugia malayi map kinase activated protein kinase protein 2 0.1186 0.3872 0.3864
Loa Loa (eye worm) CMGC/CDK/CDC2 protein kinase 0.0337 0.0792 0.0788
Trichomonas vaginalis AGC family protein kinase 0.1392 0.4621 1
Echinococcus multilocularis epidermal growth factor receptor 0.185 0.6285 0.7019
Trypanosoma brucei cdc2-related kinase 3 0.0337 0.0792 0.169
Plasmodium vivax calcium-dependent protein kinase 7, putative 0.0128 0.003 0.0101
Leishmania major protein kinase A catalytic subunit isoform 1 0.0196 0.0279 0.1076
Echinococcus granulosus macrophage colony stimulating factor 1 receptor 0.2521 0.8721 1
Echinococcus granulosus epidermal growth factor receptor 0.1209 0.3957 0.4534
Trypanosoma cruzi kinetoplastid kinetochore protein 10, putative 0.0193 0.0269 0.0965
Trichomonas vaginalis CAMK family protein kinase 0.0176 0.0207 0.0384
Echinococcus multilocularis serine:threonine protein kinase MRCK beta 0.0469 0.1271 0.1416
Trypanosoma cruzi mitogen-activated protein kinase 3, putative 0.0462 0.1243 0.4644
Trichomonas vaginalis CAMK family protein kinase 0.0804 0.2486 0.5349
Trichomonas vaginalis CAMK family protein kinase 0.0176 0.0207 0.0384
Loa Loa (eye worm) hypothetical protein 0.0275 0.0565 0.0562
Loa Loa (eye worm) AGC/PKN protein kinase 0.0742 0.2262 0.2259
Leishmania major folate/biopterin transporter, putative 0.0128 0.003 0.0069
Loa Loa (eye worm) hypothetical protein 0.0197 0.0283 0.0279
Loa Loa (eye worm) TK protein kinase 0.0412 0.1064 0.106
Trichomonas vaginalis CK1 family protein kinase 0.0227 0.0392 0.0788
Loa Loa (eye worm) hypothetical protein 0.0163 0.016 0.0156
Schistosoma mansoni chimerin-related rho-gtpase-activating protein 0.0225 0.0382 0.0588
Echinococcus multilocularis serine:threonine protein kinase PLK1 0.0804 0.2486 0.2774
Plasmodium falciparum calcium-dependent protein kinase 5 0.0188 0.0248 0.0989
Trichomonas vaginalis AGC family protein kinase 0.0148 0.0104 0.0161
Schistosoma mansoni serine/threonine protein kinase 0.0613 0.1792 0.2836
Loa Loa (eye worm) protein kinase domain-containing protein 0.0253 0.0485 0.0481
Entamoeba histolytica cell division protein kinase 2, putative 0.0337 0.0792 0.1713
Echinococcus granulosus c src tyrosine kinase 0.0305 0.0674 0.0768
Leishmania major protein kinase, putative 0.0193 0.0269 0.1034
Schistosoma mansoni tyrosine kinase 0.1099 0.3559 0.5653
Entamoeba histolytica protein kinase, putative 0.0224 0.0381 0.0825
Echinococcus multilocularis GTPase activating Rap:RanGAP domain 3 0.0134 0.0053 0.0055
Entamoeba histolytica protein kinase, putative 0.0613 0.1792 0.3878
Trichomonas vaginalis CMGC family protein kinase 0.013 0.0037 0.0015
Leishmania major protein kinase, putative,SNF1-related protein kinases, putative 0.0176 0.0207 0.0783
Loa Loa (eye worm) AGC/PKC/ETA protein kinase 0.073 0.2216 0.2213
Trichomonas vaginalis AGC family protein kinase 0.0148 0.0104 0.0161
Schistosoma mansoni defective proboscis extension response (dpr)-related 0.0212 0.0337 0.0517
Schistosoma mansoni serine/threonine protein kinase 0.0302 0.0663 0.1036
Echinococcus granulosus roundabout 2 0.0126 0.0026 0.0025
Echinococcus multilocularis aurora kinase A 0.042 0.109 0.1214
Trypanosoma cruzi cdc2-related kinase 3 0.0337 0.0792 0.2941
Brugia malayi Variant SH3 domain containing protein 0.0195 0.0276 0.0263
Echinococcus granulosus casein kinase I delta 0.0227 0.0392 0.0445
Loa Loa (eye worm) STE/STE20/TAO protein kinase 0.0262 0.0517 0.0513
Giardia lamblia Kinase, NEK 0.0391 0.0986 0.3933
Schistosoma mansoni tyrosine kinase 0.1349 0.4467 0.71
Schistosoma mansoni serine/threonine protein kinase 0.0253 0.0485 0.0752
Echinococcus granulosus tyrosine protein kinase Btk29A 0.0849 0.2649 0.3034
Giardia lamblia Kinase, CMGC GSK 0.0368 0.0902 0.3595
Loa Loa (eye worm) hypothetical protein 0.0166 0.017 0.0167
Plasmodium falciparum glycogen synthase kinase 3 0.0368 0.0902 0.365
Echinococcus multilocularis enhancer of mRNA decapping protein 4 0.0123 0.0014 0.0012
Loa Loa (eye worm) STE/STE20/SLK protein kinase 0.0232 0.0411 0.0407
Brugia malayi Protein kinase domain containing protein 0.0204 0.0307 0.0294
Entamoeba histolytica protein kinase domain containing protein 0.0368 0.0902 0.1952
Brugia malayi hypothetical protein 0.0233 0.0412 0.04
Trypanosoma cruzi mitogen-activated protein kinase 11, putative 0.0229 0.0399 0.1459
Entamoeba histolytica protein kinase domain containing protein 0.0182 0.0229 0.0496
Plasmodium vivax calcium-dependent protein kinase 4, putative 0.0188 0.0248 0.0989
Plasmodium falciparum casein kinase 1 0.0227 0.0392 0.1573
Trypanosoma cruzi polo-like protein kinase, putative 0.0804 0.2486 0.934
Trichomonas vaginalis CAMK family protein kinase 0.0804 0.2486 0.5349
Entamoeba histolytica serine/threonine protein kinase 6, putative 0.042 0.109 0.2359
Schistosoma mansoni serine/threonine protein kinase 0.0613 0.1792 0.2836
Loa Loa (eye worm) CAMK/MLCK protein kinase 0.0147 0.01 0.0096
Entamoeba histolytica protein kinase domain containing protein 0.0348 0.083 0.1796
Schistosoma mansoni proto-oncogene tyrosine-protein kinase src 0.0305 0.0674 0.1053
Brugia malayi Calcium/calmodulin-dependent protein kinase type II alpha chain 0.0188 0.0248 0.0236
Echinococcus multilocularis myosin iiia 0.0232 0.041 0.0453
Schistosoma mansoni serine/threonine protein kinase 0.0302 0.0663 0.1036
Loa Loa (eye worm) hypothetical protein 0.0233 0.0412 0.0408
Trichomonas vaginalis CAMK family protein kinase 0.0155 0.0129 0.0215
Echinococcus multilocularis glycogen synthase kinase 3 beta 0.0368 0.0902 0.1004
Echinococcus granulosus dual specificity 0.0179 0.0216 0.0243
Echinococcus multilocularis neuroglian 0.0126 0.0026 0.0024
Loa Loa (eye worm) CMGC/DYRK/DYRK2 protein kinase 0.0179 0.0216 0.0212
Trichomonas vaginalis AGC family protein kinase 0.0148 0.0104 0.0161
Plasmodium falciparum cAMP-dependent protein kinase catalytic subunit 0.0196 0.0279 0.1114
Schistosoma mansoni serine/threonine protein kinase 0.0229 0.0399 0.0616
Echinococcus multilocularis 0.0535 0.1509 0.1682
Entamoeba histolytica serine/threonine protein kinase STE20, putative 0.0232 0.041 0.0887
Trichomonas vaginalis CAMK family protein kinase 0.0176 0.0207 0.0384
Trichomonas vaginalis CAMK family protein kinase 0.0155 0.0129 0.0215
Echinococcus multilocularis dual specificity 0.0348 0.083 0.0923
Loa Loa (eye worm) CDC7 protein kinase 0.013 0.0037 0.0033
Schistosoma mansoni tyrosine kinase 0.0484 0.1324 0.209
Echinococcus granulosus maternal embryonic leucine zipper kinase 0.0155 0.0129 0.0143
Echinococcus multilocularis serine:threonine protein kinase 12 B 0.042 0.109 0.1214
Brugia malayi Protein kinase domain containing protein 0.013 0.0037 0.0024
Loa Loa (eye worm) CMGC/MAPK/P38 protein kinase 0.0462 0.1243 0.1239
Trichomonas vaginalis CAMK family protein kinase 0.0804 0.2486 0.5349
Toxoplasma gondii cell-cycle-associated protein kinase CLK, putative 0.0193 0.0269 0.0596
Entamoeba histolytica hypothetical protein 0.0139 0.007 0.0151
Echinococcus multilocularis cAMP dependent protein kinase catalytic subunit 0.0196 0.0279 0.0308
Echinococcus granulosus tyrosine protein kinase Src64B 0.0484 0.1324 0.1515
Schistosoma mansoni adapter molecule crk 0.0195 0.0276 0.0419
Brugia malayi Protein kinase domain containing protein 0.0221 0.0369 0.0357
Trichomonas vaginalis CAMK family protein kinase 0.0804 0.2486 0.5349
Leishmania major protein kinase, putative 0.0128 0.003 0.0069
Echinococcus granulosus serine:threonine protein kinase PLK1 0.0804 0.2486 0.2848
Trypanosoma cruzi dual specificity tyrosine-phosphorylation-regulated kinase 2, putative 0.0179 0.0216 0.0765
Echinococcus granulosus Vam6:Vps39 protein 0.0134 0.0053 0.0057
Echinococcus multilocularis calcium:calmodulin dependent protein kinase type 0.052 0.1456 0.1622
Schistosoma mansoni titin 0.0147 0.01 0.0139
Loa Loa (eye worm) STE/STE20/PAKA protein kinase 0.014 0.0074 0.007
Trypanosoma brucei mitogen-activated protein kinase 3, putative 0.0462 0.1243 0.2668
Toxoplasma gondii calcium-dependent protein kinase CDPK2A 0.0188 0.0248 0.055
Echinococcus multilocularis myotubularin protein 13 0.0168 0.0176 0.0192
Trichomonas vaginalis AGC family protein kinase 0.1392 0.4621 1
Giardia lamblia Aurora kinase 0.042 0.109 0.4355
Echinococcus multilocularis tyrosine protein kinase lyn lyn a protein tyrosine kinase lymphocyte specific protein tyrosine kinase 0.0484 0.1324 0.1475
Loa Loa (eye worm) TK protein kinase 0.04 0.102 0.1017
Echinococcus granulosus serine:threonine protein kinase 12 B 0.042 0.109 0.1246
Schistosoma mansoni serine/threonine protein kinase 0.0872 0.2733 0.4336
Entamoeba histolytica cell division protein kinase 2, putative 0.0337 0.0792 0.1713
Loa Loa (eye worm) hypothetical protein 0.0208 0.0321 0.0317
Trypanosoma cruzi NEK family Serine/threonine-protein kinase, putative 0.0128 0.003 0.0065
Loa Loa (eye worm) hypothetical protein 0.0221 0.0369 0.0366
Echinococcus granulosus cAMP dependent protein kinase catalytic subunit 0.0196 0.0279 0.0316
Plasmodium vivax calcium-dependent protein kinase 1, putative 0.0188 0.0248 0.0989
Brugia malayi Protein kinase c protein 2 0.0312 0.0699 0.0687
Loa Loa (eye worm) AGC/DMPK/GEK protein kinase 0.1159 0.3777 0.3775
Entamoeba histolytica protein kinase, putative 0.1392 0.4621 1
Schistosoma mansoni serine/threonine kinase 0.0613 0.1792 0.2836
Brugia malayi serine/threonine-protein kinase 6 0.042 0.109 0.1079
Entamoeba histolytica serine/threonine protein kinase, putative 0.0804 0.2486 0.538
Trichomonas vaginalis AGC family protein kinase 0.0222 0.0374 0.0749
Leishmania major glycogen synthase kinase, putative;with=GeneDB:LinJ18_V3.0270 0.0368 0.0902 0.3595
Echinococcus multilocularis fibroblast growth factor receptor 4 0.072 0.2182 0.2434
Trypanosoma cruzi STE/STE11 serine/threonine-protein kinase, putative 0.0182 0.0229 0.0816
Echinococcus multilocularis neuroglian 0.0266 0.0531 0.0589
Echinococcus granulosus tyrosine protein kinase Fyn 0.0484 0.1324 0.1515
Trichomonas vaginalis CMGC family protein kinase 0.0368 0.0902 0.1899
Trypanosoma cruzi Vacuolar sorting protein 39 domain 1/Vacuolar sorting protein 39 domain 2, putative 0.0134 0.0053 0.0152
Trichomonas vaginalis AGC family protein kinase 0.1392 0.4621 1
Trypanosoma cruzi casein kinase, delta isoform, putative 0.0154 0.0127 0.0431
Echinococcus granulosus myotubularin protein 13 0.0168 0.0176 0.0197
Schistosoma mansoni serine/threonine protein kinase 0.0469 0.1271 0.2005
Schistosoma mansoni cell adhesion molecule 0.0285 0.0602 0.0939
Echinococcus multilocularis c src tyrosine kinase 0.0305 0.0674 0.0748
Trichomonas vaginalis CAMK family protein kinase 0.0176 0.0207 0.0384
Trypanosoma cruzi kinetoplastid kinetochore protein 19, putative 0.0193 0.0269 0.0965
Onchocerca volvulus 0.0221 0.0369 0.0679
Echinococcus multilocularis dual specificity 0.0179 0.0216 0.0236
Loa Loa (eye worm) hypothetical protein 0.0427 0.1119 0.1116
Echinococcus multilocularis tyrosine protein kinase transmembrane receptor 0.0163 0.0158 0.0172
Onchocerca volvulus 0.0312 0.0701 0.1357
Entamoeba histolytica protein kinase, putative 0.042 0.109 0.2359
Brugia malayi Protein kinase domain containing protein 0.0552 0.157 0.1559
Brugia malayi Protein kinase domain containing protein 0.0384 0.0961 0.0949
Echinococcus multilocularis proto oncogene tyrosine protein kinase LCK 0.0484 0.1324 0.1475
Brugia malayi Kinase associated domain 1 family protein 0.0229 0.0398 0.0386
Trichomonas vaginalis AGC family protein kinase 0.0148 0.0104 0.0161
Trypanosoma cruzi polo-like protein kinase, putative 0.0804 0.2486 0.934
Echinococcus granulosus titin 0.0147 0.01 0.011
Trichomonas vaginalis CMGC family protein kinase 0.0179 0.0216 0.0404
Trypanosoma brucei calcium/calmodulin-dependent protein kinase, putative 0.0188 0.0248 0.0511
Trypanosoma cruzi Vacuolar sorting protein 39 domain 1/Vacuolar sorting protein 39 domain 2, putative 0.0134 0.0053 0.0152
Trypanosoma brucei serine/threonine-protein kinase NrkA 0.0128 0.003 0.0037
Brugia malayi Protein kinase domain containing protein 0.0221 0.0369 0.0357
Trichomonas vaginalis AGC family protein kinase 0.042 0.109 0.2309
Toxoplasma gondii AGC kinase 0.1337 0.4423 1
Schistosoma mansoni serine/threonine protein kinase 0.0196 0.0279 0.0424
Trichomonas vaginalis CMGC family protein kinase 0.0229 0.0399 0.0804
Echinococcus multilocularis nervana 2 0.0724 0.2197 0.2451
Brugia malayi Protein kinase domain containing protein 0.0621 0.182 0.181
Schistosoma mansoni cell adhesion molecule 0.0126 0.0026 0.002
Leishmania major cell division protein kinase 2,cdc2-related kinase 0.0337 0.0792 0.3148
Loa Loa (eye worm) CMGC/DYRK/DYRK1 protein kinase 0.0348 0.083 0.0827
Schistosoma mansoni vesicular amine transporter 0.0212 0.0337 0.0517
Toxoplasma gondii calcium dependent protein kinase CDPK8 0.0182 0.0229 0.0506
Trypanosoma cruzi rac serine-threonine kinase, putative 0.0852 0.2661 1
Trichomonas vaginalis CMGC family protein kinase 0.0179 0.0216 0.0404
Brugia malayi SH2 domain containing protein 0.0524 0.1469 0.1458
Brugia malayi EST embl|AI107989|AI107989 comes from the 3' UTR, putative 0.0473 0.1285 0.1274
Trypanosoma brucei mitogen activated protein kinase 4, putative 0.0229 0.0399 0.0838
Echinococcus multilocularis tyrosine protein kinase Srms 0.04 0.102 0.1136
Brugia malayi serine/threonine-protein kinase plk-2 0.0804 0.2486 0.2476
Loa Loa (eye worm) hypothetical protein 0.0196 0.0279 0.0275
Trypanosoma brucei CMGC/DYRK protein kinase, putative 0.0348 0.083 0.1773
Trichomonas vaginalis CMGC family protein kinase 0.0337 0.0792 0.1659
Echinococcus multilocularis expressed conserved protein 0.0174 0.02 0.0219
Trichomonas vaginalis AGC family protein kinase 0.0148 0.0104 0.0161
Schistosoma mansoni serine/threonine protein kinase 0.0302 0.0663 0.1036
Plasmodium vivax NIMA-related protein kinase (Pfnek-1), putative 0.0391 0.0986 0.399
Trichomonas vaginalis AGC family protein kinase 0.1392 0.4621 1
Echinococcus multilocularis cyclin dependent kinase 5 0.0337 0.0792 0.088
Echinococcus granulosus protein kinase c epsilon type 0.073 0.2216 0.2538
Schistosoma mansoni serine/threonine protein kinase 0.0552 0.1571 0.2484
Echinococcus granulosus calcium:calmodulin dependent protein kinase type 0.052 0.1456 0.1665
Echinococcus multilocularis calcium activated potassium channel 0.0302 0.0663 0.0736
Giardia lamblia Kinase, CMGC GSK 0.0368 0.0902 0.3595
Schistosoma mansoni tyrosine kinase 0.0484 0.1324 0.209
Onchocerca volvulus 0.0221 0.0369 0.0679
Trichomonas vaginalis AGC family protein kinase 0.0148 0.0104 0.0161
Loa Loa (eye worm) AGC/DMPK/ROCK protein kinase 0.2873 1 1
Trichomonas vaginalis CMGC family protein kinase 0.0229 0.0399 0.0804
Loa Loa (eye worm) hypothetical protein 0.0264 0.0527 0.0523
Plasmodium vivax calcium-dependent protein kinase, putative 0.0188 0.0248 0.0989
Brugia malayi Protein kinase domain containing protein 0.0488 0.1337 0.1326
Echinococcus multilocularis casein kinase I alpha 0.0227 0.0392 0.0434

Activities

Activity type Activity value Assay description Source Reference
IC50 (binding) nM Inhibitory activity of compound against recombinant human Calpain 1; No data ChEMBL. No reference
IC50 (binding) 0 nM Inhibitory activity of compound against recombinant human Calpain 1; No data ChEMBL. No reference
K obs / 1 (binding) = 136000 M-1 s-1 Inhibitory activity of compound against recombinant human Calpain 1 ChEMBL. No reference
K obs / 1 (binding) = 136000 M-1 s-1 Inhibitory activity of compound against recombinant human Calpain 1 ChEMBL. No reference

Phenotypes

Whole-cell/tissue/organism interactions

We have no records of whole-cell/tissue assays done with this compound What does this mean?

Many chemical entities in TDR Targets come from high-throughput screenings with whole cells or tissue samples, and not all assayed compounds have been tested against a single a single target protein, probably because they get ruled out during screening process. Even if these compounds may have not been of interest in the original screening, they may come as interesting leads for other screening assays. Furthermore, we may be able to propose drug-target associations using chemical similarities and network patterns.

Annotated phenotypes:

We have no manually annotated phenotypes for this drug. What does this mean? / Care to help?
In TDR Targets, information about phenotypes that are caused by drugs, or by genetic manipulation of cells (e.g. gene knockouts or knockdowns) is manually curated from the literature. These descriptions help to describe the potential of the target for drug development. If no information is available for this gene or if the information is incomplete, this may mean that i) the papers containing this information either appeared after the curation effort for this organism was carried out or they were inadvertently missed by curators; or that ii) the curation effort for this organism has not yet started.
 
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External resources for this compound

Bibliographic References

No literature references available for this target.

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