Detailed information for compound 623316

Basic information

Technical information
  • TDR Targets ID: 623316
  • Name: ethyl 3-[(4-fluorophenyl)carbamothioylamino]- 1H-indole-2-carboxylate
  • MW: 357.402 | Formula: C18H16FN3O2S
  • H donors: 3 H acceptors: 1 LogP: 4.24 Rotable bonds: 7
    Rule of 5 violations (Lipinski): 1
  • SMILES: CCOC(=O)c1[nH]c2c(c1NC(=S)Nc1ccc(cc1)F)cccc2
  • InChi: 1S/C18H16FN3O2S/c1-2-24-17(23)16-15(13-5-3-4-6-14(13)21-16)22-18(25)20-12-9-7-11(19)8-10-12/h3-10,21H,2H2,1H3,(H2,20,22,25)
  • InChiKey: AIYHPOCPTWHRNX-UHFFFAOYSA-N  


Substructure search Similarity search

Network

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Synonyms

  • 3-[[[(4-fluorophenyl)amino]-thioxomethyl]amino]-1H-indole-2-carboxylic acid ethyl ester
  • 3-[(4-fluorophenyl)thiocarbamoylamino]-1H-indole-2-carboxylic acid ethyl ester
  • ZINC02284562
  • STOCK3S-11660

Targets

Known targets for this compound

No curated genes were found associated with this compound

Predicted pathogen targets for this compound

By orthology
No druggable targets predicted by orthology data
By sequence similarity to non orthologous known druggable targets
No druggable targets predicted by sequence similarity
Obtained from network model

Ranking Plot

Putative Targets List

Species Potential target Raw Global Species
Toxoplasma gondii aldo/keto reductase family oxidoreductase 0.0025 0.0128 0.0103
Entamoeba histolytica acyl-CoA synthetase, putative 0.0025 0.0126 0.0076
Plasmodium falciparum ataxin-2 like protein, putative 0.0046 0.0338 0.0314
Loa Loa (eye worm) hypothetical protein 0.0027 0.0145 0.0137
Onchocerca volvulus 0.002 0.0082 0.0188
Entamoeba histolytica myo-inositol monophosphatase, putative 0.0036 0.0235 0.0186
Schistosoma mansoni hypothetical protein 0.0028 0.0158 0.0149
Entamoeba histolytica P-glycoprotein-1 0.002 0.0082 0.0032
Echinococcus multilocularis nuclear receptor subfamily 1 group D 0.0014 0.0023 0.0015
Echinococcus granulosus peroxisome assembly protein 26 0.0795 0.7628 0.7626
Echinococcus granulosus ATP binding cassette subfamily B MDR:TAP 0.002 0.0082 0.0074
Brugia malayi isocitrate dehydrogenase 0.0014 0.0025 0.0016
Schistosoma mansoni rab6-interacting 0.0078 0.0645 0.0637
Schistosoma mansoni photoreceptor-specific nuclear receptor related 0.0027 0.0145 0.0137
Echinococcus granulosus tubulin beta 4A class IVa 0.1039 1 1
Plasmodium falciparum AP endonuclease (DNA-[apurinic or apyrimidinic site] lyase), putative 0.0035 0.0231 0.0207
Brugia malayi Pre-SET motif family protein 0.0216 0.199 0.1983
Loa Loa (eye worm) hypothetical protein 0.0121 0.1066 0.1058
Loa Loa (eye worm) oxidoreductase 0.0086 0.0719 0.0711
Onchocerca volvulus 0.0013 0.0009 0.002
Mycobacterium tuberculosis Probable fatty-acid-CoA ligase FadD5 (fatty-acid-CoA synthetase) (fatty-acid-CoA synthase) 0.0017 0.0056 0.0149
Plasmodium vivax delta tubulin, putative 0.0246 0.2282 0.2263
Loa Loa (eye worm) cytochrome P450 family protein 0.0108 0.094 0.0932
Mycobacterium tuberculosis Cell division protein FtsZ 0.0246 0.2282 1
Brugia malayi Steroid receptor seven-up type 2 0.0027 0.0145 0.0137
Trypanosoma cruzi tubulin delta chain 0.0246 0.2282 0.2263
Echinococcus granulosus histone lysine methyltransferase setb 0.0031 0.0188 0.018
Loa Loa (eye worm) hypothetical protein 0.0014 0.0023 0.0015
Echinococcus granulosus aldo keto reductase family 1 member B4 0.0086 0.0719 0.0711
Mycobacterium ulcerans cytochrome P450 150A6 Cyp150A6 0.0102 0.088 0.3715
Schistosoma mansoni glutaminase 0.0246 0.2279 0.2273
Loa Loa (eye worm) hypothetical protein 0.0474 0.4506 0.4501
Trichomonas vaginalis alcohol dehydrogenase, putative 0.0025 0.0128 0.0104
Echinococcus granulosus retinoic acid receptor rxr beta a 0.0027 0.0145 0.0137
Mycobacterium leprae possible inositol monophosphatase SubH (IMPase) (inositol-1-phosphatase) (I-1-Pase ). 0.0032 0.0199 0.0337
Echinococcus multilocularis aldo keto reductase 0.0086 0.0719 0.0711
Echinococcus multilocularis aldo keto reductase 0.0086 0.0719 0.0711
Leishmania major beta tubulin 0.1039 1 1
Schistosoma mansoni potassium channel beta 0.0025 0.0128 0.0119
Echinococcus multilocularis inositol monophosphatase 1 0.0036 0.0235 0.0227
Mycobacterium tuberculosis Probable aldehyde dehydrogenase 0.0057 0.0443 0.1862
Schistosoma mansoni lozenge 0.0058 0.0448 0.044
Plasmodium vivax GTP-binding nuclear protein RAN/TC4, putative 0.0042 0.0291 0.0267
Treponema pallidum quinoline 2-oxidoreductase 0.0027 0.0149 0.019
Schistosoma mansoni lamin 0.0017 0.0049 0.0041
Brugia malayi Nuclear hormone receptor family member nhr-31 0.0027 0.0145 0.0137
Giardia lamblia Kinase, CMGC MAPK 0.0036 0.0237 0.0191
Mycobacterium ulcerans cytochrome P450 188A3 Cyp188A3 0.0102 0.088 0.3715
Trichomonas vaginalis dihydrodiol dehydrogenase, putative 0.0086 0.0719 0.0697
Toxoplasma gondii HEAT repeat-containing protein 0.0056 0.0436 0.0412
Toxoplasma gondii ABC transporter transmembrane region domain-containing protein 0.002 0.0082 0.0057
Toxoplasma gondii LsmAD domain-containing protein 0.0046 0.0338 0.0314
Entamoeba histolytica P-glycoprotein 5, putative 0.002 0.0082 0.0032
Mycobacterium tuberculosis Probable cytochrome P450 monooxygenase 142 Cyp142 0.0102 0.088 0.3795
Mycobacterium tuberculosis Possible cytochrome P450 126 Cyp126 0.0102 0.088 0.3795
Echinococcus multilocularis ATP binding cassette subfamily B (MDR:TAP) 0.002 0.0082 0.0074
Echinococcus multilocularis aldo keto reductase 0.0086 0.0719 0.0711
Brugia malayi Inositol-1 0.0036 0.0235 0.0227
Schistosoma mansoni tubulin subunit alpha 0.0795 0.7628 0.7626
Echinococcus multilocularis voltage gated potassium channel subunit 0.0025 0.0128 0.0119
Echinococcus granulosus tubulin alpha chain 0.0795 0.7628 0.7626
Echinococcus granulosus nuclear receptor 2DBD gamma 0.0027 0.0145 0.0137
Schistosoma mansoni jumonji domain containing protein 0.0042 0.0291 0.0283
Trichomonas vaginalis lipid A export ATP-binding/permease protein msba, putative 0.002 0.0082 0.0059
Leishmania major mitogen activated protein kinase, putative,map kinase, putative 0.0036 0.0237 0.0213
Leishmania major beta tubulin 0.1039 1 1
Trichomonas vaginalis tubulin gamma chain, putative 0.0246 0.2282 0.2264
Echinococcus granulosus Tubulin alpha 1 chain 0.0795 0.7628 0.7626
Onchocerca volvulus 0.0246 0.228 0.5227
Trichomonas vaginalis aldo-keto reductase, putative 0.0086 0.0719 0.0697
Mycobacterium tuberculosis Fatty-acid-AMP ligase FadD30 (fatty-acid-AMP synthetase) (fatty-acid-AMP synthase) 0.0018 0.0066 0.0193
Trichomonas vaginalis tubulin beta chain, putative 0.0795 0.7628 0.7622
Trypanosoma brucei beta tubulin 0.1039 1 1
Brugia malayi Tubulin beta chain 0.0321 0.3008 0.3003
Trypanosoma brucei aldo/keto reductase, putative 0.0025 0.0128 0.0103
Schistosoma mansoni ATP-binding cassette sub-family g2 (white protein) (abcg2) 0.0017 0.0051 0.0042
Onchocerca volvulus 0.0025 0.0128 0.0293
Mycobacterium tuberculosis Probable cytochrome P450 136 Cyp136 0.0102 0.088 0.3795
Mycobacterium tuberculosis Probable cytochrome P450 128 Cyp128 0.0102 0.088 0.3795
Leishmania major beta tubulin 0.1039 1 1
Loa Loa (eye worm) GTP-binding regulatory protein Gs alpha-S chain 0.009 0.0759 0.0751
Trypanosoma brucei importin beta-1 subunit, putative 0.0056 0.0436 0.0412
Entamoeba histolytica tubulin alpha chain, putative 0.0795 0.7628 0.7616
Trichomonas vaginalis aldo-keto reductase, putative 0.0086 0.0719 0.0697
Brugia malayi photoreceptor-specific nuclear receptor 0.0027 0.0145 0.0137
Trichomonas vaginalis tubulin epsilon chain, putative 0.1039 1 1
Onchocerca volvulus Heterochromatin protein 1 homolog 0.003 0.0181 0.0415
Entamoeba histolytica acyl-coA synthetase, putative 0.0025 0.0126 0.0076
Trichomonas vaginalis importin beta-1, putative 0.0046 0.0332 0.0309
Mycobacterium tuberculosis Probable cytochrome P450 141 Cyp141 0.0102 0.088 0.3795
Mycobacterium ulcerans cytochrome P450 123A3 Cyp123A3 0.0102 0.088 0.3715
Trichomonas vaginalis lipid A export ATP-binding/permease protein msba, putative 0.002 0.0082 0.0059
Echinococcus multilocularis ATP binding cassette sub family G 0.0017 0.0051 0.0042
Echinococcus multilocularis aldo keto reductase family 1, member B4 0.0086 0.0719 0.0711
Schistosoma mansoni ran 0.0042 0.0291 0.0283
Echinococcus granulosus chromobox protein 1 0.0054 0.0412 0.0404
Mycobacterium leprae putative cytochrome p450 0.0102 0.088 0.3495
Trichomonas vaginalis abcb9, putative 0.002 0.0082 0.0059
Brugia malayi Importin beta-1 subunit 0.0056 0.0436 0.0428
Brugia malayi Nuclear hormone receptor-like 1 0.0014 0.0023 0.0015
Echinococcus multilocularis snurportin 1 0.0603 0.5755 0.5751
Leishmania major cytochrome p450-like protein 0.0102 0.088 0.0857
Brugia malayi Tubulin gamma chain 0.0567 0.5404 0.54
Echinococcus multilocularis Tubulin alpha 1 chain 0.0795 0.7628 0.7626
Loa Loa (eye worm) tubulin alpha 2 0.0549 0.5232 0.5228
Leishmania major zeta tubulin, putative 0.0246 0.2282 0.2263
Brugia malayi ABC transporter family protein 0.0014 0.0026 0.0017
Echinococcus granulosus aldo keto reductase 0.0086 0.0719 0.0711
Schistosoma mansoni multidrug resistance protein 0.002 0.0082 0.0074
Schistosoma mansoni hypothetical protein 0.0056 0.0432 0.0424
Echinococcus multilocularis tubulin gamma 1 chain 0.0567 0.5404 0.54
Brugia malayi Nuclear hormone receptor family member nhr-41 0.0027 0.0145 0.0137
Brugia malayi hypothetical protein 0.0078 0.0645 0.0637
Echinococcus granulosus guanine nucleotide binding protein Gs subunit 0.009 0.0759 0.0751
Loa Loa (eye worm) hypothetical protein 0.0086 0.0719 0.0711
Echinococcus multilocularis Ataxin 2, N terminal,domain containing protein 0.0021 0.0089 0.0081
Brugia malayi MH2 domain containing protein 0.0107 0.0932 0.0924
Mycobacterium ulcerans carbon monoxyde dehydrogenase large chain CoxL 0.008 0.0667 0.2761
Brugia malayi oxidoreductase, aldo/keto reductase family protein 0.0086 0.0719 0.0711
Brugia malayi Nuclear hormone receptor family member nhr-25 0.0027 0.0145 0.0137
Brugia malayi Tubulin alpha chain 0.0795 0.7628 0.7626
Trypanosoma brucei C-8 sterol isomerase, putative 0.0264 0.2458 0.244
Trypanosoma cruzi aldo/keto reductase, putative 0.0086 0.0719 0.0696
Echinococcus granulosus FTZ F1 nuclear receptor protein 0.0027 0.0145 0.0137
Loa Loa (eye worm) hypothetical protein 0.0795 0.7628 0.7626
Onchocerca volvulus Steroid hormone receptor family member cnr14 homolog 0.0027 0.0145 0.0333
Schistosoma mansoni hypothetical protein 0.0078 0.0645 0.0637
Schistosoma mansoni nuclear hormone receptor 0.0027 0.0145 0.0137
Echinococcus multilocularis tubulin alpha 0.0567 0.5404 0.54
Loa Loa (eye worm) nuclear hormone receptor family member nhr-31 0.0027 0.0145 0.0137
Schistosoma mansoni importin beta-1 0.0056 0.0436 0.0428
Plasmodium vivax multidomain scavenger receptor, putative 0.0078 0.0645 0.0622
Echinococcus granulosus aldehyde reductase 0.0061 0.0478 0.047
Echinococcus granulosus beta tubulin 0.1039 1 1
Trichomonas vaginalis tubulin beta chain, putative 0.0795 0.7628 0.7622
Loa Loa (eye worm) glutaminase 0.0246 0.2279 0.2273
Trypanosoma cruzi Lanosterol 14-alpha demethylase 0.0102 0.088 0.0857
Mycobacterium ulcerans exodeoxyribonuclease III protein XthA 0.0035 0.0231 0.0809
Echinococcus granulosus Tubulin alpha 1 chain 0.0795 0.7628 0.7626
Toxoplasma gondii alpha tubulin TUBA1 0.0795 0.7628 0.7622
Entamoeba histolytica P-glycoprotein-5 0.002 0.0082 0.0032
Mycobacterium tuberculosis Probable short-chain type dehydrogenase/reductase 0.0066 0.0527 0.2236
Echinococcus granulosus aldo keto reductase family 1 member B4 0.0086 0.0719 0.0711
Schistosoma mansoni hypothetical protein 0.0121 0.1066 0.1058
Echinococcus granulosus tubulin alpha chain 0.0795 0.7628 0.7626
Loa Loa (eye worm) hypothetical protein 0.0031 0.0188 0.018
Treponema pallidum hypothetical protein 0.0028 0.0155 0.0218
Echinococcus granulosus RUN 0.0078 0.0645 0.0637
Echinococcus granulosus snurportin 1 0.0603 0.5755 0.5751
Mycobacterium ulcerans cytochrome P450 189A7 Cyp189A7 0.0102 0.088 0.3715
Brugia malayi Nuclear hormone receptor family member nhr-49 0.0027 0.0145 0.0137
Schistosoma mansoni NADP-specific isocitrate dehydrogenase 0.0014 0.0025 0.0016
Plasmodium falciparum GTP-binding nuclear protein RAN/TC4 0.0042 0.0291 0.0267
Brugia malayi jmjC domain containing protein 0.0042 0.0291 0.0283
Brugia malayi ecdysteroid receptor 0.0027 0.0145 0.0137
Giardia lamblia Endonuclease/Exonuclease/phosphatase 0.0035 0.0231 0.0185
Trypanosoma brucei prostaglandin f synthase 0.0086 0.0719 0.0696
Mycobacterium ulcerans cytochrome P450 124A1, Cyp124A1 0.0102 0.088 0.3715
Trichomonas vaginalis CMGC family protein kinase 0.0036 0.0237 0.0214
Mycobacterium ulcerans acyl-CoA synthetase 0.0025 0.0126 0.0338
Trichomonas vaginalis abcb9, putative 0.002 0.0082 0.0059
Plasmodium falciparum aldo-keto reductase, putative 0.0025 0.0128 0.0103
Echinococcus multilocularis GPCR, family 2 0.0056 0.0432 0.0424
Leishmania major mitogen activated protein kinase 4, putative;with=GeneDB:LmxM19.1440 0.0036 0.0237 0.0213
Leishmania major alpha tubulin 0.0795 0.7628 0.7622
Echinococcus granulosus tubulin alpha 0.0567 0.5404 0.54
Brugia malayi Calcitonin receptor-like protein seb-1 0.0177 0.1612 0.1605
Schistosoma mansoni inositol monophosphatase 0.0036 0.0235 0.0227
Brugia malayi ERG2 and Sigma1 receptor like protein 0.0264 0.2458 0.2452
Mycobacterium tuberculosis Probable chain -fatty-acid-CoA ligase FadD13 (fatty-acyl-CoA synthetase) 0.0025 0.0126 0.0461
Schistosoma mansoni thyroid hormone receptor 0.0027 0.0145 0.0137
Echinococcus multilocularis aldo keto reductase 0.0086 0.0719 0.0711
Echinococcus multilocularis ecdysone induced protein 78C 0.0027 0.0145 0.0137
Echinococcus granulosus multidrug resistance protein 1 0.002 0.0082 0.0074
Schistosoma mansoni smdr2 0.002 0.0082 0.0074
Brugia malayi beta-tubulin, identical 0.1039 1 1
Mycobacterium ulcerans long-chain-fatty-acid--CoA ligase 0.0025 0.0126 0.0338
Echinococcus multilocularis aldo keto reductase family 1, member B4 0.0086 0.0719 0.0711
Schistosoma mansoni ecdysone-induced protein 78c (dr-78) 0.0014 0.0023 0.0015
Schistosoma mansoni ap endonuclease 0.0035 0.0231 0.0223
Loa Loa (eye worm) hypothetical protein 0.0025 0.0126 0.0118
Loa Loa (eye worm) hypothetical protein 0.0025 0.0126 0.0118
Leishmania major alpha tubulin 0.0795 0.7628 0.7622
Loa Loa (eye worm) oxidoreductase 0.0086 0.0719 0.0711
Loa Loa (eye worm) hypothetical protein 0.0116 0.1013 0.1005
Plasmodium falciparum ataxin-2 like protein, putative 0.0046 0.0338 0.0314
Echinococcus granulosus beta tubulin 0.1039 1 1
Echinococcus multilocularis tubulin subunit TubB 0.0795 0.7628 0.7626
Schistosoma mansoni tubulin subunit beta 0.1039 1 1
Trypanosoma brucei beta tubulin 0.1039 1 1
Echinococcus multilocularis importin subunit beta 1 0.0056 0.0436 0.0428
Loa Loa (eye worm) transcription factor SMAD2 0.0107 0.0932 0.0924
Entamoeba histolytica exodeoxyribonuclease III, putative 0.0035 0.0231 0.0181
Brugia malayi MAP kinase sur-1 0.0036 0.0237 0.0229
Echinococcus granulosus tubulin epsilon chain 0.0567 0.5404 0.54
Leishmania major 4-coumarate:coa ligase-like protein 0.0025 0.0126 0.0102
Trypanosoma cruzi GTP-binding nuclear protein rtb2, putative 0.0042 0.0291 0.0267
Trichomonas vaginalis CMGC family protein kinase 0.0036 0.0237 0.0214
Trichomonas vaginalis tubulin gamma chain, putative 0.0567 0.5404 0.5393
Echinococcus granulosus ATP binding cassette sub family G 0.0017 0.0051 0.0042
Schistosoma mansoni microtubule-associated protein tau 0.0692 0.6625 0.6622
Schistosoma mansoni jumonji/arid domain-containing protein 0.0042 0.0291 0.0283
Mycobacterium ulcerans carbon monoxyde dehydrogenase large chain CoxL 0.005 0.0377 0.1463
Echinococcus granulosus GPCR family 2 0.0056 0.0432 0.0424
Onchocerca volvulus 0.0078 0.0645 0.1478
Echinococcus granulosus GTP binding nuclear protein Ran 0.0042 0.0291 0.0283
Mycobacterium ulcerans glutaminase 0.0246 0.2279 0.9987
Onchocerca volvulus 0.0017 0.0049 0.0113
Echinococcus multilocularis Nuclear hormone receptor family member nhr 41 0.0027 0.0145 0.0137
Mycobacterium tuberculosis Cytochrome P450 121 Cyp121 0.0102 0.088 0.3795
Plasmodium vivax SET domain protein, putative 0.0031 0.0188 0.0164
Chlamydia trachomatis ABC transporter ATP binding protein/permease 0.002 0.0082 1
Loa Loa (eye worm) cytochrome P450 0.0102 0.088 0.0872
Brugia malayi steroid hormone receptor 0.0027 0.0145 0.0137
Schistosoma mansoni chromobox protein 0.0054 0.0412 0.0404
Echinococcus multilocularis ATP binding cassette sub family B 0.002 0.0078 0.007
Brugia malayi Nuclear hormone receptor family member nhr-25 0.0027 0.0145 0.0137
Echinococcus multilocularis Basic leucine zipper (bZIP) transcription 0.0028 0.0158 0.0149
Toxoplasma gondii tubulin/FtsZ family, GTPase domain-containing protein 0.0567 0.5404 0.5393
Echinococcus granulosus Basic leucine zipper bZIP transcription 0.0028 0.0158 0.0149
Echinococcus granulosus tubulin delta chain 0.0246 0.2282 0.2276
Mycobacterium tuberculosis Probable transmembrane multidrug efflux pump 0.002 0.0082 0.0266
Echinococcus granulosus 5'partial|histone lysine N methyltransferase SETDB2 0.003 0.0177 0.0169
Schistosoma mansoni loxhd1 0.0078 0.0645 0.0637
Onchocerca volvulus 0.0078 0.0645 0.1478
Trichomonas vaginalis ran, putative 0.0042 0.0291 0.0268
Brugia malayi Cytochrome P450 family protein 0.0102 0.088 0.0872
Schistosoma mansoni jumonji/arid domain-containing protein 0.0042 0.0291 0.0283
Brugia malayi Cytochrome P450 family protein 0.0108 0.094 0.0932
Echinococcus multilocularis ATP binding cassette sub family G 0.0017 0.0051 0.0042
Trypanosoma brucei GTP-binding nuclear protein rtb2, putative 0.0042 0.0291 0.0267
Onchocerca volvulus 0.0086 0.0719 0.1649
Leishmania major GTP-binding protein, putative 0.0042 0.0291 0.0267
Mycobacterium ulcerans cytochrome P450 187A4 Cyp187A4 0.0102 0.088 0.3715
Trichomonas vaginalis xanthine dehydrogenase, putative 0.017 0.1541 0.1521
Toxoplasma gondii tubulin/FtsZ family, GTPase domain-containing protein 0.0246 0.2282 0.2263
Leishmania major aldo/keto reductase, putative,aldo/keto reductase family-like protein 0.0025 0.0128 0.0103
Schistosoma mansoni cytochrome P450 0.0102 0.088 0.0872
Echinococcus granulosus Transcription factor JmjC domain containing protein 0.0042 0.0291 0.0283
Mycobacterium ulcerans cytochrome P450 125A7 Cyp125A7 0.0102 0.088 0.3715
Echinococcus multilocularis tubulin alpha chain 0.0795 0.7628 0.7626
Loa Loa (eye worm) hypothetical protein 0.0046 0.0338 0.033
Leishmania major prostaglandin f synthase, putative 0.0086 0.0719 0.0696
Loa Loa (eye worm) CMGC/MAPK/ERK1 protein kinase 0.0036 0.0237 0.0229
Loa Loa (eye worm) hypothetical protein 0.0027 0.0145 0.0137
Mycobacterium tuberculosis Probable cytochrome P450 137 Cyp137 0.0102 0.088 0.3795
Entamoeba histolytica aldose reductase, putative 0.0086 0.0719 0.0672
Trypanosoma cruzi cytochrome P450, putative 0.0108 0.094 0.0917
Echinococcus granulosus 3 hydroxyacyl coenzyme A dehydrogenase type 2 0.0066 0.0527 0.0519
Loa Loa (eye worm) nuclear Hormone Receptor family member 0.0027 0.0145 0.0137
Trichomonas vaginalis multidrug resistance protein 1, 2, putative 0.002 0.0082 0.0059
Giardia lamblia Aldose reductase 0.0086 0.0719 0.0676
Echinococcus multilocularis Polycystic kidney disease protein 0.0078 0.0645 0.0637
Onchocerca volvulus Nuclear receptor subfamily 6 group A member 1 homolog 0.0013 0.0009 0.002
Trypanosoma cruzi mitogen-activated protein kinase 11, putative 0.0036 0.0237 0.0213
Loa Loa (eye worm) hypothetical protein 0.0025 0.0126 0.0118
Toxoplasma gondii beta tubulin 0.1039 1 1
Schistosoma mansoni tubulin subunit beta 0.0246 0.2282 0.2276
Mycobacterium leprae Conserved hypothetical protein 0.0102 0.088 0.3495
Wolbachia endosymbiont of Brugia malayi cell division protein FtsZ 0.0246 0.2282 1
Schistosoma mansoni 3-hydroxyacyl-CoA dehydrogenase 0.0066 0.0527 0.0519
Onchocerca volvulus Protein ultraspiracle homolog 0.0027 0.0145 0.0333
Schistosoma mansoni Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) 0.009 0.0759 0.0751
Echinococcus granulosus hypothetical protein 0.0086 0.0719 0.0711
Echinococcus granulosus tubulin subunit beta 0.1039 1 1
Plasmodium falciparum ABC transporter G family member 2 0.0017 0.0051 0.0026
Trichomonas vaginalis ATP-binding cassette transporter, putative 0.002 0.0082 0.0059
Entamoeba histolytica hypothetical protein 0.0028 0.0158 0.0108
Trypanosoma brucei zeta tubulin, putative 0.0246 0.2282 0.2263
Brugia malayi Nuclear hormone receptor family member nhr-14 0.0027 0.0145 0.0137
Onchocerca volvulus 0.0086 0.0719 0.1649
Mycobacterium tuberculosis Possible cytochrome P450 135A1 Cyp135A1 0.0102 0.088 0.3795
Trichomonas vaginalis Importin beta-1 subunit, putative 0.0046 0.0332 0.0309
Echinococcus multilocularis aldo keto reductase family 1, member B4 0.0086 0.0719 0.0711
Toxoplasma gondii CMGC kinase, MAPK family (ERK) MAPK-1 0.0036 0.0237 0.0213
Echinococcus multilocularis FTZ F1 alpha 0.0027 0.0145 0.0137
Brugia malayi Heterochromatin protein 1 0.0054 0.0412 0.0404
Trichomonas vaginalis aldo-keto reductase, putative 0.0086 0.0719 0.0697
Schistosoma mansoni serine/threonine protein kinase 0.0036 0.0237 0.0229
Leishmania major alpha tubulin 0.0795 0.7628 0.7622
Giardia lamblia Beta tubulin 0.1039 1 1
Plasmodium vivax tubulin alpha chain, putative 0.0795 0.7628 0.7622
Echinococcus granulosus aldo keto reductase family 1 member B4 0.0086 0.0719 0.0711
Trypanosoma cruzi mitogen activated protein kinase 4, putative 0.0036 0.0237 0.0213
Trichomonas vaginalis CMGC family protein kinase 0.0036 0.0237 0.0214
Trypanosoma cruzi Lanosterol 14-alpha demethylase 0.0102 0.088 0.0857
Loa Loa (eye worm) hypothetical protein 0.0135 0.1201 0.1194
Loa Loa (eye worm) beta-tubulin 0.1039 1 1
Mycobacterium ulcerans cytochrome P450 143A3 Cyp143A3 0.0102 0.088 0.3715
Wolbachia endosymbiont of Brugia malayi fructose-1,6-bisphosphatase 0.0036 0.0235 0.0021
Onchocerca volvulus 0.0025 0.0126 0.0289
Mycobacterium tuberculosis Probable exodeoxyribonuclease III protein XthA (exonuclease III) (EXO III) (AP endonuclease VI) 0.0035 0.0231 0.0925
Leishmania major alpha tubulin 0.0795 0.7628 0.7622
Trypanosoma cruzi beta tubulin, putative 0.1039 1 1
Brugia malayi GTP-binding regulatory protein Gs alpha-S chain, putative 0.009 0.0759 0.0751
Trypanosoma brucei alpha tubulin 0.0795 0.7628 0.7622
Loa Loa (eye worm) hypothetical protein 0.0116 0.1013 0.1005
Brugia malayi glutamate-cysteine ligase modifier subunit 0.0025 0.0128 0.0119
Mycobacterium tuberculosis Probable cytochrome P450 125 Cyp125 0.0102 0.088 0.3795
Trypanosoma brucei protein kinase, putative 0.0036 0.0237 0.0213
Schistosoma mansoni multidrug resistance protein 0.002 0.0082 0.0074
Trypanosoma cruzi myo-inositol-1(or 4)-monophosphatase 1, putative 0.0036 0.0235 0.0211
Loa Loa (eye worm) tubulin beta-4 chain 0.1039 1 1
Trypanosoma cruzi C-8 sterol isomerase, putative 0.0264 0.2458 0.244
Trichomonas vaginalis conserved hypothetical protein 0.0025 0.0128 0.0104
Echinococcus granulosus alpha tubulin 0.0795 0.7628 0.7626
Mycobacterium ulcerans cytochrome P450 185A4 Cyp185A4 0.0108 0.094 0.3985
Leishmania major lanosterol 14-alpha-demethylase, putative 0.0102 0.088 0.0857
Loa Loa (eye worm) isocitrate dehydrogenase 0.0014 0.0025 0.0016
Echinococcus multilocularis mitogen activated protein kinase 3 0.0036 0.0237 0.0229
Loa Loa (eye worm) hypothetical protein 0.0018 0.0066 0.0057
Echinococcus granulosus microtubule associated protein 2 0.0692 0.6625 0.6622
Leishmania major beta tubulin 0.1039 1 1
Loa Loa (eye worm) steroid hormone receptor 0.0027 0.0145 0.0137
Echinococcus granulosus diuretic hormone 44 receptor GPRdih2 0.0056 0.0432 0.0424
Echinococcus granulosus aldo keto reductase family 1 member B4 0.0086 0.0719 0.0711
Loa Loa (eye worm) hypothetical protein 0.0018 0.0066 0.0057
Trichomonas vaginalis ap endonuclease, putative 0.0035 0.0231 0.0208
Echinococcus multilocularis nuclear receptor 2DBD gamma 0.0027 0.0145 0.0137
Echinococcus multilocularis lysine specific demethylase 5A 0.0042 0.0291 0.0283
Trypanosoma brucei epsilon tubulin 0.0567 0.5404 0.5393
Plasmodium vivax tubulin gamma chain, putative 0.0567 0.5404 0.5393
Mycobacterium tuberculosis Probable cytochrome P450 140 Cyp140 0.0102 0.088 0.3795
Schistosoma mansoni tubulin subunit gamma 0.0567 0.5404 0.54
Loa Loa (eye worm) hypothetical protein 0.0264 0.2458 0.2452
Brugia malayi Nuclear hormone receptor family member nhr-19 0.0027 0.0145 0.0137
Trichomonas vaginalis tubulin beta-1 chain, putative 0.0246 0.2282 0.2264
Echinococcus granulosus mitogen activated protein kinase 0.0036 0.0237 0.0229
Mycobacterium tuberculosis Probable cytochrome P450 138 Cyp138 0.0102 0.088 0.3795
Schistosoma mansoni tubulin subunit alpha 0.0246 0.2282 0.2276
Brugia malayi hypothetical protein 0.0142 0.1271 0.1263
Echinococcus granulosus tubulin subunit TubB 0.0795 0.7628 0.7626
Schistosoma mansoni rab6-interacting 0.0078 0.0645 0.0637
Echinococcus multilocularis histone lysine methyltransferase setb histone lysine methyltransferase eggless 0.0031 0.0188 0.018
Trypanosoma brucei ABC transporter, putative 0.0017 0.0051 0.0026
Loa Loa (eye worm) hypothetical protein 0.0027 0.0145 0.0137
Loa Loa (eye worm) hypothetical protein 0.0078 0.0645 0.0637
Echinococcus multilocularis chromobox protein 1 0.0054 0.0412 0.0404
Echinococcus granulosus tubulin alpha 3 chain 0.0795 0.7628 0.7626
Trypanosoma brucei zeta tubulin 0.0246 0.2282 0.2263
Schistosoma mansoni aldehyde dehydrogenase 0.0057 0.0443 0.0435
Leishmania major beta tubulin 0.1039 1 1
Echinococcus multilocularis COUP TF:Svp nuclear hormone receptor 0.0027 0.0145 0.0137
Schistosoma mansoni steroid hormone receptor ad4bp 0.0027 0.0145 0.0137
Entamoeba histolytica P-glyco protein 6, putative 0.002 0.0082 0.0032
Plasmodium falciparum LCCL domain-containing protein 0.0078 0.0645 0.0622
Mycobacterium ulcerans acyl-CoA synthetase 0.0025 0.0126 0.0338
Echinococcus granulosus ATP binding cassette sub family G 0.0017 0.0051 0.0042
Trichomonas vaginalis tubulin, putative 0.0246 0.2282 0.2264
Schistosoma mansoni hypothetical protein 0.0102 0.088 0.0872
Leishmania major hypothetical protein, conserved 0.0046 0.0338 0.0314
Loa Loa (eye worm) nuclear hormone receptor family member nhr-14 0.0027 0.0145 0.0137
Trypanosoma cruzi zeta tubulin, putative 0.0246 0.2282 0.2263
Trypanosoma cruzi epsilon tubulin, putative 0.0567 0.5404 0.5393
Schistosoma mansoni lamin 0.0017 0.0049 0.0041
Trypanosoma cruzi aldo-keto reductase 0.0086 0.0719 0.0696
Brugia malayi RNA, U transporter 1 0.0161 0.145 0.1442
Echinococcus granulosus importin subunit beta 1 0.0056 0.0436 0.0428
Echinococcus multilocularis Tubulin beta 2C chain 0.1039 1 1
Loa Loa (eye worm) hypothetical protein 0.0017 0.0049 0.0041
Brugia malayi Intermediate filament tail domain containing protein 0.0017 0.0049 0.0041
Trypanosoma brucei beta tubulin 0.0567 0.5404 0.5393
Trichomonas vaginalis abcb9, putative 0.002 0.0082 0.0059
Echinococcus granulosus ATP binding cassette subfamily B MDR:TAP 0.002 0.0082 0.0074
Plasmodium falciparum tubulin gamma chain 0.0567 0.5404 0.5393
Echinococcus multilocularis tubulin alpha 1C chain 0.0795 0.7628 0.7626
Echinococcus multilocularis guanine nucleotide binding protein G(s) subunit 0.009 0.0759 0.0751
Trichomonas vaginalis multidrug resistance protein 1, 2, putative 0.002 0.0082 0.0059
Giardia lamblia Epsilon tubulin 0.0246 0.2282 0.2246
Plasmodium vivax ABC transporter G family member 2, putative 0.0017 0.0051 0.0026
Trypanosoma brucei alpha tubulin, putative 0.0321 0.3008 0.2991
Trichomonas vaginalis aldo-keto reductase, putative 0.0086 0.0719 0.0697
Mycobacterium tuberculosis Probable carbon monoxyde dehydrogenase (medium chain) 0.0057 0.0445 0.1872
Brugia malayi latrophilin 2 splice variant baaae 0.0121 0.1066 0.1058
Mycobacterium ulcerans cytochrome P450 136A2 Cyp136A2 0.0102 0.088 0.3715
Echinococcus multilocularis ATP binding cassette subfamily B (MDR:TAP) 0.002 0.0082 0.0074
Brugia malayi Corticotropin releasing factor receptor 2 precursor, putative 0.0177 0.1612 0.1605
Echinococcus multilocularis isocitrate dehydrogenase 0.0014 0.0025 0.0016
Loa Loa (eye worm) tubulin alpha-2 chain 0.0795 0.7628 0.7626
Plasmodium falciparum alpha tubulin 2 0.0795 0.7628 0.7622
Echinococcus multilocularis Protein lozenge 0.0058 0.0448 0.044
Onchocerca volvulus Heterochromatin protein 1 homolog 0.0033 0.0203 0.0466
Brugia malayi hypothetical protein 0.0028 0.0158 0.0149
Mycobacterium ulcerans long-chain fatty-acid CoA ligase 0.0025 0.0126 0.0338
Loa Loa (eye worm) hypothetical protein 0.0014 0.0023 0.0015
Brugia malayi GTP-binding nuclear protein RAN/TC4 0.0042 0.0291 0.0283
Trypanosoma cruzi apurinic/apyrimidinic endonuclease 0.0035 0.0231 0.0207
Schistosoma mansoni histone-lysine n-methyltransferase setb1 0.0031 0.0188 0.018
Trichomonas vaginalis tubulin alpha chain, putative 0.1039 1 1
Loa Loa (eye worm) GTP-binding nuclear protein RAN/TC4 0.0042 0.0291 0.0283
Echinococcus multilocularis Tubulin alpha 1 chain 0.0795 0.7628 0.7626
Schistosoma mansoni hypothetical protein 0.0312 0.2922 0.2916
Echinococcus granulosus intermediate filament protein 0.0017 0.0049 0.0041
Brugia malayi AMP-binding enzyme family protein 0.0025 0.0126 0.0118
Schistosoma mansoni intermediate filament proteins 0.0017 0.0049 0.0041
Mycobacterium tuberculosis Conserved protein 0.0025 0.0128 0.0468
Mycobacterium tuberculosis Probable cytochrome P450 143 Cyp143 0.0102 0.088 0.3795
Echinococcus multilocularis lipoxygenase domain containing protein 0.0078 0.0645 0.0637
Onchocerca volvulus 0.0017 0.0049 0.0113
Echinococcus granulosus ATP binding cassette subfamily B MDR:TAP 0.002 0.0082 0.0074
Echinococcus multilocularis Tubulin beta 2C chain 0.1039 1 1
Trichomonas vaginalis conserved hypothetical protein 0.003 0.0181 0.0158
Trichomonas vaginalis ABC transporter, putative 0.002 0.0082 0.0059
Brugia malayi ABC transporter family protein 0.002 0.0082 0.0074
Plasmodium vivax tubulin epsilon chain, putative 0.0567 0.5404 0.5393
Trichomonas vaginalis aldo-keto reductase, putative 0.0086 0.0719 0.0697
Mycobacterium ulcerans carbon monoxyde dehydrogenase small chain CoxS 0.0032 0.0202 0.068
Trichomonas vaginalis conserved hypothetical protein 0.0246 0.2282 0.2264
Brugia malayi exodeoxyribonuclease III family protein 0.0035 0.0231 0.0223
Loa Loa (eye worm) heterochromatin protein 1 0.0054 0.0412 0.0404
Mycobacterium tuberculosis Probable cytochrome P450 139 Cyp139 0.0102 0.088 0.3795
Trypanosoma brucei beta tubulin 0.1039 1 1
Brugia malayi Cytochrome P450 family protein 0.0124 0.1093 0.1085
Echinococcus multilocularis GTP binding nuclear protein Ran 0.0042 0.0291 0.0283
Mycobacterium ulcerans carbon monoxyde dehydrogenase medium chain CoxM 0.0057 0.0445 0.1768
Echinococcus multilocularis Tubulin beta 2C chain 0.1039 1 1
Loa Loa (eye worm) intermediate filament protein 0.0017 0.0049 0.0041
Trichomonas vaginalis tubulin alpha chain, putative 0.0321 0.3008 0.2992
Echinococcus multilocularis ATP binding cassette subfamily B (MDR:TAP) 0.002 0.0082 0.0074
Onchocerca volvulus 0.004 0.0274 0.0628
Trypanosoma brucei tubulin delta chain 0.0246 0.2282 0.2263
Loa Loa (eye worm) tubulin alpha chain 0.0795 0.7628 0.7626
Echinococcus multilocularis nuclear receptor 2DBD gamma 0.0027 0.0145 0.0137
Schistosoma mansoni multidrug resistance protein 0.002 0.0082 0.0074
Mycobacterium tuberculosis Cytochrome P450 51 Cyp51 (CYPL1) (P450-L1A1) (sterol 14-alpha demethylase) (lanosterol 14-alpha demethylase) (P450-14DM) 0.0102 0.088 0.3795
Echinococcus multilocularis tubulin alpha chain 0.0795 0.7628 0.7626
Echinococcus multilocularis tubulin delta chain 0.0246 0.2282 0.2276
Loa Loa (eye worm) ATP-binding cassette sub-family B member 2 0.002 0.0082 0.0074
Onchocerca volvulus 0.0086 0.0719 0.1649
Echinococcus granulosus lipoxygenase domain containing protein 0.0078 0.0645 0.0637
Leishmania major apurinic/apyrimidinic endonuclease-redox protein 0.0035 0.0231 0.0207
Mycobacterium ulcerans cell division protein FtsZ 0.0246 0.2282 1
Brugia malayi jmjC domain containing protein 0.0042 0.0291 0.0283
Trichomonas vaginalis chromobox protein, putative 0.0033 0.0203 0.018
Echinococcus multilocularis geminin 0.0312 0.2922 0.2916
Echinococcus granulosus geminin 0.0312 0.2922 0.2916
Loa Loa (eye worm) hypothetical protein 0.0014 0.0023 0.0015
Echinococcus multilocularis atpase aaa+ type core atpase aaa type core 0.0628 0.5999 0.5996
Echinococcus multilocularis tubulin alpha 1C chain 0.0795 0.7628 0.7626
Trichomonas vaginalis lipid A export ATP-binding/permease protein msba, putative 0.002 0.0082 0.0059
Plasmodium vivax acyl-CoA synthetase, putative 0.0018 0.0066 0.0041
Schistosoma mansoni hypothetical protein 0.0021 0.0089 0.0081
Brugia malayi Nuclear hormone receptor-like 1 0.0014 0.0023 0.0015
Schistosoma mansoni histone-lysine n-methyltransferase suv9 0.004 0.0274 0.0266
Entamoeba histolytica aldose reductase, putative 0.0086 0.0719 0.0672
Echinococcus multilocularis hypothetical protein 0.0795 0.7628 0.7626
Toxoplasma gondii aldehyde dehydrogenase 0.0057 0.0443 0.0419
Loa Loa (eye worm) BEN-1 protein 0.1039 1 1
Leishmania major beta tubulin 0.1039 1 1
Loa Loa (eye worm) doublecortin family protein 0.0078 0.0645 0.0637
Entamoeba histolytica hypothetical protein 0.0028 0.0158 0.0108
Echinococcus granulosus tubulin alpha 3 chain 0.0795 0.7628 0.7626
Loa Loa (eye worm) nuclear hormone receptor-like 1 0.0014 0.0023 0.0015
Toxoplasma gondii alpha-tubulin I, putative 0.0795 0.7628 0.7622
Trichomonas vaginalis tubulin alpha chain, putative 0.0321 0.3008 0.2992
Echinococcus multilocularis aldo keto reductase family 1, member B4 0.0086 0.0719 0.0711
Mycobacterium tuberculosis Inositol-1-monophosphatase SuhB 0.0032 0.0199 0.0782
Mycobacterium ulcerans cytochrome P450 187A5 Cyp187A5 0.0102 0.088 0.3715
Schistosoma mansoni transcription factor LCR-F1 0.0028 0.0158 0.0149
Schistosoma mansoni retinoid-x-receptor (RXR) 0.0014 0.0023 0.0015
Leishmania major delta tubulin, putative 0.0246 0.2282 0.2263
Echinococcus granulosus muscleblind protein 0.0116 0.1013 0.1005
Echinococcus multilocularis aldehyde dehydrogenase, mitochondrial 0.0057 0.0443 0.0435
Leishmania major beta tubulin 0.1039 1 1
Mycobacterium ulcerans cytochrome P450 108B4 Cyp108B4 0.0102 0.088 0.3715
Echinococcus multilocularis NADP dependent isocitrate dehydrogenase 0.0014 0.0025 0.0016
Plasmodium falciparum tubulin delta chain, putative 0.0246 0.2282 0.2263
Echinococcus granulosus nuclear receptor subfamily 1 group D 0.0014 0.0023 0.0015
Loa Loa (eye worm) nuclear hormone receptor family member nhr-49 0.0027 0.0145 0.0137
Trichomonas vaginalis chromobox protein, putative 0.0054 0.0412 0.0389
Schistosoma mansoni chromobox protein 0.0054 0.0412 0.0404
Trichomonas vaginalis tubulin beta chain, putative 0.0321 0.3008 0.2992
Mycobacterium ulcerans cytochrome P450 144A4 Cyp144A4 0.0102 0.088 0.3715
Brugia malayi Tubulin beta chain 0.0246 0.2282 0.2276
Trypanosoma cruzi importin beta-1 subunit, putative 0.0046 0.0332 0.0308
Onchocerca volvulus 0.0086 0.0719 0.1649
Loa Loa (eye worm) alpha-tubulin 0.0795 0.7628 0.7626
Brugia malayi NADH-dependent xylose reductase 0.0025 0.0128 0.0119
Plasmodium vivax oxidoreductase, aldo/keto reductase domain containing protein 0.0025 0.0128 0.0103
Brugia malayi Doublecortin family protein 0.0078 0.0645 0.0637
Trichomonas vaginalis taga, putative 0.002 0.0082 0.0059
Trypanosoma cruzi mitogen activated protein kinase 2, putative 0.0036 0.0237 0.0213
Schistosoma mansoni histone-lysine n-methyltransferase setb1 0.0031 0.0188 0.018
Echinococcus granulosus Tubulin beta 2C chain 0.1039 1 1
Echinococcus granulosus tubulin beta 1 chain 0.1039 1 1
Schistosoma mansoni tubulin subunit alpha 0.0795 0.7628 0.7626
Schistosoma mansoni coup transcription factor 0.0027 0.0145 0.0137
Trichomonas vaginalis tubulin epsilon chain, putative 0.0795 0.7628 0.7622
Plasmodium falciparum tubulin beta chain 0.1039 1 1
Brugia malayi nuclear receptor NHR-88 0.0027 0.0145 0.0137
Mycobacterium ulcerans hypothetical protein 0.0025 0.0128 0.0346
Trypanosoma cruzi tubulin delta chain 0.0246 0.2282 0.2263
Leishmania major beta tubulin 0.1039 1 1
Echinococcus granulosus tubulin gamma 1 chain 0.0567 0.5404 0.54
Trichomonas vaginalis ATP-binding cassette transporter, putative 0.002 0.0082 0.0059
Brugia malayi Tubulin alpha-2 chain 0.0795 0.7628 0.7626
Leishmania major beta tubulin 0.1039 1 1
Trichomonas vaginalis ap endonuclease, putative 0.0035 0.0231 0.0208
Echinococcus multilocularis 0.0102 0.088 0.0872
Schistosoma mansoni Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) 0.009 0.0759 0.0751
Trypanosoma cruzi cytochrome P450, putative 0.0108 0.094 0.0917
Brugia malayi tubulin alpha chain - mouse 0.0795 0.7628 0.7626
Leishmania major 4-coumarate:coa ligase-like protein 0.0025 0.0126 0.0102
Giardia lamblia Aldose reductase 0.0086 0.0719 0.0676
Loa Loa (eye worm) BEN-1 protein 0.1039 1 1
Trichomonas vaginalis dihydrodiol dehydrogenase, putative 0.0086 0.0719 0.0697
Mycobacterium tuberculosis Probable carbon monoxyde dehydrogenase (small chain) 0.0032 0.0202 0.0798
Loa Loa (eye worm) tubulin alpha 2 0.0549 0.5232 0.5228
Trichomonas vaginalis tubulin alpha-1 chain, putative 0.0549 0.5232 0.5221
Loa Loa (eye worm) pre-SET domain-containing protein family protein 0.0216 0.199 0.1983
Loa Loa (eye worm) hypothetical protein 0.0078 0.0645 0.0637
Trichomonas vaginalis lipid A export ATP-binding/permease protein msba, putative 0.002 0.0082 0.0059
Mycobacterium ulcerans carbon monoxide dehydrogenase 0.0113 0.0983 0.4176
Trichomonas vaginalis chromobox protein, putative 0.0054 0.0412 0.0389
Loa Loa (eye worm) multidrug resistance protein 3 0.002 0.0082 0.0074
Echinococcus granulosus mitogen activated protein kinase 3 0.0036 0.0237 0.0229
Echinococcus granulosus lamin 0.0017 0.0049 0.0041
Echinococcus multilocularis tubulin epsilon chain 0.0567 0.5404 0.54
Loa Loa (eye worm) latrophilin receptor protein 2 0.0056 0.0432 0.0424
Entamoeba histolytica P-glycoprotein-2 0.002 0.0082 0.0032
Mycobacterium ulcerans short-chain type dehydrogenase/reductase 0.0066 0.0527 0.2137
Trichomonas vaginalis conserved hypothetical protein 0.0021 0.0095 0.0071
Schistosoma mansoni hypothetical protein 0.0056 0.0432 0.0424
Echinococcus granulosus nuclear receptor 2DBD gamma 0.0027 0.0145 0.0137
Loa Loa (eye worm) tubulin beta chain 0.0246 0.2282 0.2276
Mycobacterium tuberculosis Probable cytochrome P450 130 Cyp130 0.0102 0.088 0.3795
Schistosoma mansoni hypothetical protein 0.0056 0.0432 0.0424
Brugia malayi hypothetical protein 0.0014 0.0023 0.0015
Trichomonas vaginalis ABC transporter, putative 0.002 0.0082 0.0059
Onchocerca volvulus 0.0086 0.0719 0.1649
Echinococcus multilocularis musashi 0.0017 0.0049 0.0041
Trypanosoma brucei Lanosterol 14-alpha demethylase 0.0102 0.088 0.0857
Trichomonas vaginalis myo inositol monophosphatase, putative 0.0036 0.0235 0.0212
Schistosoma mansoni Tr4/Tr2 (homologue) 0.0027 0.0145 0.0137
Mycobacterium ulcerans aerobic-type carbon monoxide dehydrogenase subunit CoxM_2 0.0057 0.0445 0.1768
Loa Loa (eye worm) hypothetical protein 0.0027 0.0145 0.0137
Brugia malayi cytochrome P450 0.0102 0.088 0.0872
Echinococcus granulosus DNA apurinic or apyrimidinic site lyase 0.0035 0.0231 0.0223
Entamoeba histolytica tubulin family protein 0.1039 1 1
Trypanosoma cruzi alpha tubulin, putative 0.0795 0.7628 0.7622
Loa Loa (eye worm) oxidoreductase 0.0086 0.0719 0.0711
Loa Loa (eye worm) tubulin beta-2A chain 0.1039 1 1
Loa Loa (eye worm) jmjC domain-containing protein 0.0042 0.0291 0.0283
Leishmania major beta tubulin 0.1039 1 1
Brugia malayi Ligand-binding domain of nuclear hormone receptor family protein 0.0027 0.0145 0.0137
Echinococcus granulosus aldo keto reductase family 1 member B4 0.0086 0.0719 0.0711
Mycobacterium ulcerans cytochrome P450 126A3 Cyp126A3 0.0102 0.088 0.3715
Trichomonas vaginalis lipid A export ATP-binding/permease protein msba, putative 0.002 0.0082 0.0059
Echinococcus multilocularis aldo keto reductase family 1, member B4 0.0086 0.0719 0.0711
Toxoplasma gondii histone lysine methyltransferase SET/SUV39 0.0031 0.0188 0.0164
Leishmania major alpha tubulin 0.0795 0.7628 0.7622
Mycobacterium ulcerans cytochrome P450 51B1 Cyp51B1 0.0102 0.088 0.3715
Toxoplasma gondii tubulin/FtsZ family, GTPase domain-containing protein 0.0246 0.2282 0.2263
Echinococcus granulosus aldo keto reductase family 1 member B4 0.0086 0.0719 0.0711
Echinococcus multilocularis muscleblind protein 1 0.0116 0.1013 0.1005
Trichomonas vaginalis aldo-keto reductase, putative 0.0086 0.0719 0.0697
Mycobacterium ulcerans cytochrome p450 150 cyp150 0.0102 0.088 0.3715
Leishmania major alpha tubulin 0.0795 0.7628 0.7622
Trypanosoma cruzi GTP-binding nuclear protein rtb2, putative 0.0042 0.0291 0.0267
Schistosoma mansoni Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) 0.009 0.0759 0.0751
Brugia malayi nuclear hormone receptor 0.0027 0.0145 0.0137
Trichomonas vaginalis chromobox protein, putative 0.0033 0.0203 0.018
Brugia malayi intermediate filament protein 0.0017 0.0049 0.0041
Mycobacterium tuberculosis Probable fatty-acid-CoA ligase FadD35 (fatty-acid-CoA synthetase) (fatty-acid-CoA synthase) 0.0017 0.0056 0.0149
Loa Loa (eye worm) glutamate-cysteine ligase modifier subunit 0.0025 0.0128 0.0119
Trichomonas vaginalis aldo/keto reductase, putative 0.0086 0.0719 0.0697
Onchocerca volvulus 0.046 0.4362 1
Loa Loa (eye worm) hypothetical protein 0.0018 0.0066 0.0057
Brugia malayi Nuclear hormone receptor-like 1 0.0027 0.0145 0.0137
Echinococcus multilocularis chromobox protein 1 0.0054 0.0412 0.0404
Trichomonas vaginalis tubulin beta chain, putative 0.0795 0.7628 0.7622
Echinococcus granulosus multidrug resistance protein 1 0.002 0.0082 0.0074
Brugia malayi Tubulin alpha-2 chain 0.0795 0.7628 0.7626
Mycobacterium tuberculosis Probable fatty-acid-CoA ligase FadD2 (fatty-acid-CoA synthetase) (fatty-acid-CoA synthase) 0.0025 0.0126 0.0461
Loa Loa (eye worm) nuclear hormone receptor family member nhr-41 0.0027 0.0145 0.0137
Trichomonas vaginalis xanthine dehydrogenase, putative 0.017 0.1541 0.1521
Trypanosoma brucei epsilon tubulin 0.0567 0.5404 0.5393
Echinococcus granulosus Polycystic kidney disease protein 0.0078 0.0645 0.0637
Loa Loa (eye worm) hypothetical protein 0.0014 0.0023 0.0015
Trypanosoma cruzi apurinic/apyrimidinic endonuclease, putative 0.0035 0.0231 0.0207
Schistosoma mansoni retinoic acid receptor RXR 0.0027 0.0145 0.0137
Echinococcus multilocularis isocitrate dehydrogenase 2 (NADP+) 0.0014 0.0025 0.0016
Trypanosoma brucei tubulin gamma chain 0.0567 0.5404 0.5393
Echinococcus multilocularis thyroid hormone receptor alpha 0.0027 0.0145 0.0137
Trichomonas vaginalis aldo/keto reductase, putative 0.0086 0.0719 0.0697
Echinococcus granulosus chromobox protein 1 0.0054 0.0412 0.0404
Trichomonas vaginalis aldo-keto reductase, putative 0.0086 0.0719 0.0697
Schistosoma mansoni ABC transporter 0.0014 0.0026 0.0017
Echinococcus granulosus aldo keto reductase 0.0086 0.0719 0.0711
Echinococcus multilocularis RUN 0.0078 0.0645 0.0637
Echinococcus multilocularis NADP dependent isocitrate dehydrogenase 0.0014 0.0025 0.0016
Echinococcus multilocularis ATP binding cassette sub family G 0.0017 0.0051 0.0042
Loa Loa (eye worm) hypothetical protein 0.0027 0.0145 0.0137
Brugia malayi AMP-binding enzyme family protein 0.0025 0.0126 0.0118
Trypanosoma brucei alpha tubulin 0.0795 0.7628 0.7622
Echinococcus multilocularis peroxisome assembly protein 26 0.0795 0.7628 0.7626
Loa Loa (eye worm) hypothetical protein 0.0027 0.0145 0.0137
Trypanosoma cruzi cytochrome p450-like protein, putative 0.0102 0.088 0.0857
Schistosoma mansoni tubulin subunit beta 0.1039 1 1
Entamoeba histolytica tubulin gamma chain 0.0567 0.5404 0.5381
Leishmania major prostaglandin f2-alpha synthase/D-arabinose dehydrogenase 0.0086 0.0719 0.0696
Echinococcus granulosus Tubulin beta 2C chain 0.1039 1 1
Plasmodium vivax AP endonuclease (DNA-[apurinic or apyrimidinic site] lyase), putative 0.0035 0.0231 0.0207
Brugia malayi 3-hydroxyacyl-CoA dehydrogenase type II 0.0066 0.0527 0.0519
Loa Loa (eye worm) MH2 domain-containing protein 0.0107 0.0932 0.0924
Trichomonas vaginalis lipid A export ATP-binding/permease protein msba, putative 0.002 0.0082 0.0059
Mycobacterium ulcerans cytochrome P450 142A3 Cyp142A3 0.0102 0.088 0.3715
Schistosoma mansoni alpha tubulin 0.0795 0.7628 0.7626
Schistosoma mansoni histone-lysine n-methyltransferase setb1 0.0031 0.0188 0.018
Leishmania major alpha tubulin 0.0795 0.7628 0.7622
Plasmodium vivax multidrug resistance protein 1, putative 0.002 0.0082 0.0057
Entamoeba histolytica alcohol dehydrogenase, putative 0.0025 0.0128 0.0078
Trichomonas vaginalis glutaminase, putative 0.0246 0.2279 0.2261
Leishmania major 4-coumarate:coa ligase-like protein 0.0025 0.0126 0.0102
Echinococcus granulosus aldo keto reductase 0.0086 0.0719 0.0711
Loa Loa (eye worm) hypothetical protein 0.0018 0.0066 0.0057
Echinococcus multilocularis mitogen activated protein kinase 0.0036 0.0237 0.0229
Loa Loa (eye worm) cytochrome P450 family protein 0.0108 0.094 0.0932
Schistosoma mansoni retinoid-x-receptor (RXR) 0.0027 0.0145 0.0137
Echinococcus granulosus lipoxygenase domain containing protein 0.0078 0.0645 0.0637
Trypanosoma cruzi zeta tubulin, putative 0.0246 0.2282 0.2263
Leishmania major beta tubulin 0.1039 1 1
Trichomonas vaginalis Importin beta-1 subunit, putative 0.0046 0.0332 0.0309
Schistosoma mansoni hypothetical protein 0.0056 0.0432 0.0424
Loa Loa (eye worm) tubulin gamma chain 0.0567 0.5404 0.54
Trichomonas vaginalis aldo-keto reductase, putative 0.0086 0.0719 0.0697
Echinococcus multilocularis tubulin alpha chain 0.0795 0.7628 0.7626
Mycobacterium ulcerans acyl-CoA synthetase 0.0025 0.0126 0.0338
Trichomonas vaginalis tubulin, putative 0.0321 0.3008 0.2992
Echinococcus granulosus tubulin alpha chain 0.0795 0.7628 0.7626
Echinococcus multilocularis tubulin beta 1 chain 0.1039 1 1
Trichomonas vaginalis lipid A export ATP-binding/permease protein msba, putative 0.002 0.0082 0.0059
Mycobacterium ulcerans hypothetical protein 0.0025 0.0126 0.0338
Loa Loa (eye worm) hypothetical protein 0.046 0.4362 0.4358
Echinococcus multilocularis histone lysine N methyltransferase SETMAR 0.0031 0.0188 0.018
Trichomonas vaginalis aldo/keto reductase, putative 0.0086 0.0719 0.0697
Loa Loa (eye worm) tubulin beta-1 chain 0.1039 1 1
Toxoplasma gondii ATP-binding cassette G family transporter ABCG84 0.0017 0.0051 0.0026
Leishmania major beta tubulin 0.1039 1 1
Trypanosoma cruzi PAB1-binding protein , putative 0.0046 0.0338 0.0314
Echinococcus multilocularis cadherin EGF LAG seven pass G type receptor 0.0056 0.0432 0.0424
Brugia malayi hypothetical protein 0.003 0.0178 0.017
Trichomonas vaginalis multidrug resistance protein 1, 2, putative 0.002 0.0082 0.0059
Onchocerca volvulus 0.0027 0.0145 0.0333
Mycobacterium tuberculosis Probable cytochrome P450 123 Cyp123 0.0102 0.088 0.3795
Leishmania major ATP-binding cassette protein subfamily B, member 2, putative 0.002 0.0082 0.0057
Trichomonas vaginalis aldo-keto reductase, putative 0.0086 0.0719 0.0697
Brugia malayi Cell division protein ftsZ 0.0246 0.2282 0.2276
Loa Loa (eye worm) tubulin alpha chain 0.0795 0.7628 0.7626
Mycobacterium tuberculosis Probable cytochrome P450 132 Cyp132 0.0102 0.088 0.3795
Leishmania major aldehyde reductase, putative,oxidoreductase, putative 0.0086 0.0719 0.0696
Trypanosoma brucei beta tubulin 0.1039 1 1
Leishmania major gamma-tubulin 0.0567 0.5404 0.5393
Entamoeba histolytica tubulin alpha-1 chain 0.0795 0.7628 0.7616
Toxoplasma gondii beta-tubulin, putative 0.1039 1 1
Loa Loa (eye worm) exodeoxyribonuclease III family protein 0.0035 0.0231 0.0223
Brugia malayi Tubulin alpha chain 0.0246 0.2282 0.2276
Plasmodium falciparum tubulin epsilon chain, putative 0.0567 0.5404 0.5393
Echinococcus multilocularis tubulin subunit beta 0.1039 1 1
Echinococcus granulosus Ataxin 2 N terminaldomain containing protein 0.0021 0.0089 0.0081
Trichomonas vaginalis inositol monophosphatase, putative 0.0036 0.0235 0.0212
Trypanosoma brucei alpha tubulin 0.0795 0.7628 0.7622
Onchocerca volvulus 0.0321 0.3008 0.6896
Mycobacterium ulcerans hypothetical protein 0.0028 0.0155 0.047
Trypanosoma cruzi mitogen-activated protein kinase 11, putative 0.0036 0.0237 0.0213
Brugia malayi Ligand-binding domain of nuclear hormone receptor family protein 0.0027 0.0145 0.0137
Echinococcus multilocularis lipoxygenase domain containing protein 0.0078 0.0645 0.0637
Mycobacterium ulcerans extragenic suppressor protein SuhB 0.0036 0.0235 0.0828
Leishmania major aldo-keto reductase-like protein 0.0086 0.0719 0.0696
Echinococcus granulosus ATP binding cassette sub family G 0.0017 0.0051 0.0042
Mycobacterium ulcerans cytochrome P450 105Q4 Cyp105Q4 0.0102 0.088 0.3715
Echinococcus multilocularis 3 hydroxyacyl coenzyme A dehydrogenase type 2 0.0066 0.0527 0.0519
Treponema pallidum cell division protein FtsZ 0.0246 0.2282 1
Echinococcus multilocularis guanine nucleotide binding protein G(s) subunit 0.009 0.0759 0.0751
Mycobacterium tuberculosis Possible cytochrome P450 135B1 Cyp135B1 0.0102 0.088 0.3795
Trichomonas vaginalis ATP-binding cassette transporter, putative 0.002 0.0082 0.0059
Echinococcus granulosus COUP TF:Svp nuclear hormone receptor 0.0027 0.0145 0.0137
Echinococcus multilocularis beta tubulin 0.1039 1 1
Entamoeba histolytica hypothetical protein 0.0028 0.0158 0.0108
Leishmania major beta tubulin 0.1039 1 1
Toxoplasma gondii aldo-keto reductase 0.0025 0.0128 0.0103
Echinococcus multilocularis aldo keto reductase family 1, member B4 0.0086 0.0719 0.0711
Schistosoma mansoni alpha tubulin 0.0795 0.7628 0.7626
Mycobacterium tuberculosis Probable isocitrate dehydrogenase [NADP] Icd1 (oxalosuccinate decarboxylase) (IDH) (NADP+-specific ICDH) (IDP) 0.0014 0.0025 0.0013
Brugia malayi oxidoreductase, aldo/keto reductase family protein 0.0086 0.0719 0.0711
Trichomonas vaginalis aldo-keto reductase, putative 0.0086 0.0719 0.0697
Mycobacterium ulcerans fatty-acid-CoA ligase 0.0025 0.0126 0.0338
Loa Loa (eye worm) inositol-1 0.0036 0.0235 0.0227
Leishmania major p-glycoprotein 0.002 0.0082 0.0057
Mycobacterium leprae Possible oxidoreductase 0.0025 0.0128 0.0008
Trichomonas vaginalis tubulin beta chain, putative 0.1039 1 1
Echinococcus multilocularis muscleblind protein 0.0116 0.1013 0.1005
Mycobacterium ulcerans fatty-acid-CoA ligase 0.0018 0.0066 0.0067
Giardia lamblia Beta tubulin 0.1039 1 1
Echinococcus granulosus tubulin alpha 1C chain 0.0795 0.7628 0.7626
Echinococcus granulosus 5'partial|ATP binding cassette sub family B 0.002 0.0078 0.007
Loa Loa (eye worm) nuclear hormone receptor family member nhr-40 0.0027 0.0145 0.0137
Mycobacterium leprae PROBABLE OXIDOREDUCTASE 0.0086 0.0719 0.2751
Trichomonas vaginalis tubulin alpha-1 chain, putative 0.0474 0.4506 0.4493
Entamoeba histolytica P-glycoprotein-2 0.002 0.0082 0.0032
Treponema pallidum exodeoxyribonuclease (exoA) 0.0035 0.0231 0.0566
Trichomonas vaginalis tubulin epsilon chain, putative 0.0246 0.2282 0.2264
Loa Loa (eye worm) hypothetical protein 0.002 0.0082 0.0074
Leishmania major ATP-binding cassette protein subfamily G, member 6, putative 0.0017 0.0051 0.0026
Loa Loa (eye worm) oxidoreductase 0.0086 0.0719 0.0711
Trichomonas vaginalis aldo-keto reductase, putative 0.0086 0.0719 0.0697
Trichomonas vaginalis multidrug resistance protein 1, 2, putative 0.002 0.0082 0.0059
Leishmania major beta tubulin 0.1039 1 1
Loa Loa (eye worm) ABC transporter 0.0014 0.0026 0.0017
Brugia malayi Isocitrate dehydrogenase 0.0014 0.0025 0.0016
Brugia malayi AMP-binding enzyme family protein 0.0025 0.0126 0.0118
Echinococcus multilocularis microtubule associated protein 2 0.0692 0.6625 0.6622
Loa Loa (eye worm) hypothetical protein 0.0024 0.0117 0.0109
Mycobacterium tuberculosis Probable fatty-acid-CoA ligase FadD3 (fatty-acid-CoA synthetase) (fatty-acid-CoA synthase) 0.0017 0.0056 0.0149
Trichomonas vaginalis ABC transporter, putative 0.002 0.0082 0.0059
Plasmodium vivax aldehyde reductase, putative 0.0025 0.0128 0.0103
Echinococcus granulosus Tubulin alpha 1 chain 0.0795 0.7628 0.7626
Loa Loa (eye worm) tubulin alpha-3 chain 0.0474 0.4506 0.4501
Plasmodium falciparum multidrug resistance protein 1 0.002 0.0082 0.0057
Trichomonas vaginalis ABC transporter, half transporter, putative 0.002 0.0082 0.0059
Schistosoma mansoni nuclear receptor 2DBD-gamma 0.0027 0.0145 0.0137
Trichomonas vaginalis dihydrodiol dehydrogenase, putative 0.0086 0.0719 0.0697
Schistosoma mansoni lipoxygenase 0.0264 0.2455 0.2448
Trypanosoma brucei epsilon tubulin 0.0567 0.5404 0.5393
Schistosoma mansoni nuclear hormone receptor nor-1/nor-2 0.0027 0.0145 0.0137
Mycobacterium ulcerans oxidoreductase 0.0086 0.0719 0.2996
Echinococcus multilocularis tubulin, beta 4A class IVa 0.1039 1 1
Leishmania major ATP-binding cassette protein subfamily G, member 4, putative 0.0017 0.0051 0.0026
Trypanosoma cruzi ABC transporter, putative 0.0017 0.0051 0.0026
Brugia malayi hypothetical protein 0.046 0.4362 0.4358
Toxoplasma gondii exonuclease III APE 0.0035 0.0231 0.0207
Trypanosoma brucei cytochrome P450, putative 0.0108 0.094 0.0917
Echinococcus multilocularis hepatocyte nuclear factor 4 alpha 0.0027 0.0145 0.0137
Giardia lamblia Alpha-tubulin 0.0795 0.7628 0.7617
Schistosoma mansoni hypothetical protein 0.0603 0.5755 0.5751
Trypanosoma cruzi PAB1-binding protein , putative 0.0046 0.0338 0.0314
Trichomonas vaginalis myo inositol monophosphatase, putative 0.0036 0.0235 0.0212
Echinococcus multilocularis diuretic hormone 44 receptor GPRdih2 0.0056 0.0432 0.0424
Echinococcus multilocularis FTZ F1 nuclear receptor protein 0.0027 0.0145 0.0137
Trichomonas vaginalis tubulin, putative 0.1039 1 1
Trypanosoma cruzi aldo/keto reductase, putative 0.0025 0.0128 0.0103
Leishmania major alpha tubulin 0.0795 0.7628 0.7622
Trichomonas vaginalis tubulin beta chain, putative 0.0795 0.7628 0.7622
Brugia malayi nuclear receptor RXR 0.0014 0.0023 0.0015
Leishmania major cytochrome p450-like protein 0.0102 0.088 0.0857
Leishmania major importin beta-1 subunit, putative 0.0046 0.0332 0.0308
Trypanosoma brucei PAB1-binding protein , putative 0.0046 0.0338 0.0314
Trichomonas vaginalis tubulin, putative 0.0321 0.3008 0.2992
Echinococcus multilocularis DNA (apurinic or apyrimidinic site) lyase 0.0035 0.0231 0.0223
Trichomonas vaginalis tubulin epsilon chain, putative 0.0795 0.7628 0.7622
Schistosoma mansoni pol-related 0.0086 0.0719 0.0711
Brugia malayi oxidoreductase, aldo/keto reductase family protein 0.0086 0.0719 0.0711
Echinococcus multilocularis multidrug resistance protein 1 0.002 0.0082 0.0074
Loa Loa (eye worm) intermediate filament tail domain-containing protein 0.0017 0.0049 0.0041
Schistosoma mansoni aldo-keto reductase 0.0086 0.0719 0.0711
Schistosoma mansoni hypothetical protein 0.0014 0.0022 0.0013
Mycobacterium tuberculosis Probable cytochrome P450 124 Cyp124 0.0102 0.088 0.3795
Echinococcus multilocularis Transcription factor, JmjC domain containing protein 0.0042 0.0291 0.0283
Echinococcus granulosus Tubulin beta 2C chain 0.1039 1 1
Echinococcus multilocularis Tubulin beta 2C chain 0.1039 1 1
Mycobacterium ulcerans aldehyde dehydrogenase 0.0057 0.0443 0.1757
Trichomonas vaginalis conserved hypothetical protein 0.0246 0.2282 0.2264
Trypanosoma cruzi myo-inositol-1(or 4)-monophosphatase 1, putative 0.0036 0.0235 0.0211
Schistosoma mansoni thyroid hormone receptor 0.0027 0.0145 0.0137
Leishmania major C-8 sterol isomerase-like protein 0.0264 0.2458 0.244
Trichomonas vaginalis CMGC family protein kinase 0.0036 0.0237 0.0214
Echinococcus granulosus NADP dependent isocitrate dehydrogenase 0.0014 0.0025 0.0016
Echinococcus granulosus Nuclear hormone receptor family member nhr 41 0.0027 0.0145 0.0137
Plasmodium vivax importin-beta 2, putative 0.0056 0.0436 0.0412
Trypanosoma brucei mitogen activated protein kinase 4, putative 0.0036 0.0237 0.0213
Schistosoma mansoni aldehyde dehydrogenase 0.0057 0.0443 0.0435
Schistosoma mansoni tubulin subunit epsilon 0.0567 0.5404 0.54
Leishmania major alpha tubulin 0.0795 0.7628 0.7622
Toxoplasma gondii beta-1 tubulin, putative 0.1039 1 1
Echinococcus granulosus lamin dm0 0.0017 0.0049 0.0041
Schistosoma mansoni RAR-like nuclear receptor 0.0027 0.0145 0.0137
Trichomonas vaginalis lipid A export ATP-binding/permease protein msba, putative 0.002 0.0082 0.0059
Loa Loa (eye worm) hypothetical protein 0.0177 0.1612 0.1605
Schistosoma mansoni alpha tubulin 0.0795 0.7628 0.7626
Giardia lamblia Alpha-tubulin 0.0795 0.7628 0.7617
Loa Loa (eye worm) CYP4Cod1 0.0108 0.094 0.0932
Echinococcus granulosus cadherin EGF LAG seven pass G type receptor 0.0056 0.0432 0.0424
Mycobacterium ulcerans cytochrome P450 143A4 Cyp143A4 0.0102 0.088 0.3715
Trichomonas vaginalis set domain proteins, putative 0.0246 0.228 0.2262
Brugia malayi Latrophilin receptor protein 2 0.0056 0.0432 0.0424
Plasmodium vivax tubulin beta chain, putative 0.1039 1 1
Leishmania major 3-oxoacyl-(acyl-carrier protein) reductase, putative 0.0066 0.0527 0.0504
Trichomonas vaginalis tubulin gamma chain, putative 0.1039 1 1
Trichomonas vaginalis ABC transporter, putative 0.002 0.0082 0.0059
Echinococcus granulosus ATP binding cassette subfamily B MDR:TAP 0.002 0.0082 0.0074
Brugia malayi hypothetical protein 0.0046 0.0338 0.033
Trichomonas vaginalis multidrug resistance protein 1, 2, putative 0.002 0.0082 0.0059
Brugia malayi alpha-tubulin 0.0795 0.7628 0.7626
Trichomonas vaginalis aldo-keto reductase, putative 0.0025 0.0128 0.0104
Mycobacterium ulcerans aldehyde dehydrogenase 0.0057 0.0443 0.1757
Plasmodium falciparum acyl-CoA synthetase 0.0018 0.0066 0.0041
Trichomonas vaginalis ATP-binding cassette transporter, putative 0.002 0.0082 0.0059
Brugia malayi multidrug resistance protein 3 0.002 0.0082 0.0074
Echinococcus granulosus arachidonate 5 lipoxygenase 0.0404 0.382 0.3814
Echinococcus granulosus guanine nucleotide binding protein Gs subunit 0.009 0.0759 0.0751
Schistosoma mansoni tubulin subunit beta 0.1039 1 1
Plasmodium falciparum alpha tubulin 1 0.0795 0.7628 0.7622
Echinococcus multilocularis Tubulin beta 2C chain 0.1039 1 1
Schistosoma mansoni FTZ-F1 nuclear receptor-like protein 0.0027 0.0145 0.0137
Leishmania major aldehyde dehydrogenase, mitochondrial precursor 0.0057 0.0443 0.0419
Echinococcus multilocularis aldo keto reductase family 1, member B4 0.0086 0.0719 0.0711
Leishmania major beta tubulin 0.1039 1 1
Echinococcus multilocularis aldo keto reductase family 1, member B4 0.0086 0.0719 0.0711
Mycobacterium ulcerans aldehyde dehydrogenase 0.0057 0.0443 0.1757
Brugia malayi hypothetical protein 0.0014 0.0023 0.0015
Loa Loa (eye worm) hypothetical protein 0.0142 0.1271 0.1263
Leishmania major beta tubulin 0.1039 1 1
Leishmania major alpha tubulin 0.0795 0.7628 0.7622
Schistosoma mansoni lipoxygenase 0.0404 0.382 0.3814
Mycobacterium ulcerans short-chain type dehydrogenase/reductase 0.0066 0.0527 0.2137
Echinococcus multilocularis Tubulin alpha 1 chain 0.0795 0.7628 0.7626
Trichomonas vaginalis tubulin gamma chain, putative 0.0567 0.5404 0.5393
Trichomonas vaginalis tubulin epsilon chain, putative 0.1039 1 1
Brugia malayi glutaminase DH11.1 0.0246 0.2279 0.2273
Echinococcus granulosus Tubulin beta 2C chain 0.1039 1 1
Trichomonas vaginalis aldo-keto reductase, putative 0.0086 0.0719 0.0697
Trichomonas vaginalis tubulin beta chain, putative 0.0795 0.7628 0.7622
Mycobacterium ulcerans long-chain-fatty-acid-CoA ligase 0.0025 0.0126 0.0338
Loa Loa (eye worm) tubulin beta chain 0.1039 1 1
Brugia malayi Nuclear hormone receptor family member nhr-19 0.0027 0.0145 0.0137
Echinococcus granulosus aldehyde dehydrogenase mitochondrial 0.0057 0.0443 0.0435
Plasmodium vivax tubulin alpha chain, putative 0.0795 0.7628 0.7622
Trichomonas vaginalis tubulin alpha chain, putative 0.0321 0.3008 0.2992
Schistosoma mansoni ap endonuclease 0.0035 0.0231 0.0223
Entamoeba histolytica tubulin family protein 0.1039 1 1
Trichomonas vaginalis tubulin alpha-1 chain, putative 0.0795 0.7628 0.7622
Mycobacterium leprae cell division protein FtsZ 0.0246 0.2282 1
Brugia malayi Pre-SET motif family protein 0.0031 0.0188 0.018
Loa Loa (eye worm) hypothetical protein 0.0027 0.0145 0.0137
Brugia malayi Muscleblind-like protein 0.0116 0.1013 0.1005
Echinococcus granulosus cytochrome P450 2K1 0.0102 0.088 0.0872
Trypanosoma brucei inositol-1(or 4)-monophosphatase 1, putative 0.0036 0.0235 0.0211
Echinococcus granulosus Tubulin beta 2C chain 0.1039 1 1
Schistosoma mansoni hypothetical protein 0.0312 0.2922 0.2916
Schistosoma mansoni tubulin subunit alpha 0.0795 0.7628 0.7626
Trichomonas vaginalis conserved hypothetical protein 0.0021 0.0095 0.0071
Toxoplasma gondii inositol(myo)-1(or 4)-monophosphatase 2, putative 0.0036 0.0235 0.0211
Brugia malayi Nuclear hormone receptor family member nhr-40 0.0027 0.0145 0.0137
Echinococcus granulosus tubulin alpha chain 0.0795 0.7628 0.7626
Brugia malayi Nuclear hormone receptor family member nhr-1 0.0027 0.0145 0.0137
Loa Loa (eye worm) runx1 0.0058 0.0448 0.044
Trichomonas vaginalis multidrug resistance protein 1, 2, putative 0.002 0.0082 0.0059
Loa Loa (eye worm) hypothetical protein 0.0027 0.0145 0.0137
Brugia malayi oxidoreductase, aldo/keto reductase family protein 0.0086 0.0719 0.0711
Trichomonas vaginalis conserved hypothetical protein 0.003 0.0181 0.0158
Echinococcus granulosus aldo keto reductase family 1 member B4 0.0086 0.0719 0.0711
Echinococcus multilocularis aldo keto reductase family 1, member B4 0.0086 0.0719 0.0711
Mycobacterium ulcerans aerobic-type carbon monoxide dehydrogenase subunit CoxL_2 0.008 0.0667 0.2761
Toxoplasma gondii ATP-binding cassette transporter ABC.B1 0.002 0.0082 0.0057
Leishmania major myo-inositol-1(or 4)-monophosphatase 1, putative 0.0036 0.0235 0.0211
Trypanosoma cruzi tubulin gamma chain 0.0567 0.5404 0.5393
Mycobacterium tuberculosis Probable fatty-acid-CoA ligase FadD7 (fatty-acid-CoA synthetase) (fatty-acid-CoA synthase) 0.0017 0.0056 0.0149
Echinococcus multilocularis tubulin alpha chain 0.0795 0.7628 0.7626
Loa Loa (eye worm) hypothetical protein 0.002 0.0082 0.0074
Loa Loa (eye worm) oxidoreductase 0.0086 0.0719 0.0711
Schistosoma mansoni tubulin subunit beta 0.1039 1 1
Entamoeba histolytica aldose reductase, putative 0.0086 0.0719 0.0672
Loa Loa (eye worm) hypothetical protein 0.0056 0.0432 0.0424
Plasmodium falciparum importin beta, putative 0.0056 0.0436 0.0412
Trichomonas vaginalis tubulin beta chain, putative 0.0795 0.7628 0.7622
Loa Loa (eye worm) hypothetical protein 0.046 0.4362 0.4358
Brugia malayi Cytochrome P450 family protein 0.0108 0.094 0.0932
Loa Loa (eye worm) hypothetical protein 0.0018 0.0066 0.0057
Mycobacterium ulcerans carbon monoxyde dehydrogenase small chain CoxS 0.0032 0.0202 0.068
Trypanosoma cruzi epsilon tubulin, putative 0.0567 0.5404 0.5393
Echinococcus granulosus voltage gated potassium channel subunit 0.0025 0.0128 0.0119
Mycobacterium tuberculosis Probable carbon monoxyde dehydrogenase (large chain) 0.008 0.0667 0.2852
Onchocerca volvulus 0.0024 0.0117 0.0269
Echinococcus multilocularis multidrug resistance protein 1 0.002 0.0082 0.0074
Trichomonas vaginalis multidrug resistance protein 1, 2, putative 0.002 0.0082 0.0059
Mycobacterium tuberculosis Probable oxidoreductase 0.0086 0.0719 0.3085
Schistosoma mansoni inositol monophosphatase 0.0036 0.0235 0.0227
Echinococcus granulosus inositol monophosphatase 1 0.0036 0.0235 0.0227
Echinococcus granulosus multidrug resistance protein 1 0.002 0.0082 0.0074
Echinococcus granulosus lysine specific demethylase 5A 0.0042 0.0291 0.0283
Echinococcus multilocularis tubulin alpha chain 0.0795 0.7628 0.7626
Giardia lamblia GTP-binding nuclear protein RAN/TC4 0.0042 0.0291 0.0246
Echinococcus multilocularis tubulin alpha 3 chain 0.0795 0.7628 0.7626
Trichomonas vaginalis ATP-binding cassette transporter, putative 0.002 0.0082 0.0059
Plasmodium falciparum aldehyde reductase, putative 0.0025 0.0128 0.0103
Loa Loa (eye worm) 3-hydroxyacyl-CoA dehydrogenase type II 0.0061 0.0484 0.0476
Echinococcus multilocularis ATP binding cassette subfamily B (MDR:TAP) 0.002 0.0082 0.0074
Entamoeba histolytica alcohol dehydrogenase, putative 0.0025 0.0128 0.0078
Schistosoma mansoni aldo-keto reductase 0.0086 0.0719 0.0711
Echinococcus granulosus aldo keto reductase family 1, member B4 0.0025 0.0128 0.0119
Echinococcus granulosus aldo keto reductase family 1 member B4 0.0086 0.0719 0.0711
Schistosoma mansoni polycystin 1-related 0.0078 0.0645 0.0637
Toxoplasma gondii oxidoreductase, aldo/keto reductase family protein 0.0025 0.0128 0.0103
Loa Loa (eye worm) nucleolar RNA-associated protein alpha 0.0603 0.5755 0.5751
Loa Loa (eye worm) pigment dispersing factor receptor c 0.0177 0.1612 0.1605
Trichomonas vaginalis aldehyde oxidase, putative 0.017 0.1541 0.1521
Echinococcus multilocularis aldo keto reductase family 1, member B4 0.0086 0.0719 0.0711
Plasmodium vivax ataxin-2 like protein, putative 0.0046 0.0338 0.0314
Echinococcus granulosus tubulin alpha 1C chain 0.0795 0.7628 0.7626
Echinococcus granulosus ecdysone induced protein 78C 0.0027 0.0145 0.0137
Leishmania major alpha tubulin 0.0795 0.7628 0.7622
Schistosoma mansoni ran 0.0042 0.0291 0.0283
Trypanosoma brucei aldo-keto reductase, putative 0.0086 0.0719 0.0696
Echinococcus granulosus multidrug resistance protein 1 0.0014 0.0024 0.0015
Trichomonas vaginalis tubulin alpha chain, putative 0.0567 0.5404 0.5393
Loa Loa (eye worm) hypothetical protein 0.0016 0.0046 0.0038
Onchocerca volvulus Bile acid receptor homolog 0.0027 0.0145 0.0333
Onchocerca volvulus Nuclear receptor subfamily 6 group A member 1 homolog 0.0013 0.0009 0.002
Mycobacterium tuberculosis Probable cytochrome P450 144 Cyp144 0.0102 0.088 0.3795
Brugia malayi hypothetical protein 0.0078 0.0645 0.0637
Toxoplasma gondii cytochrome p450 superfamily protein 0.0102 0.088 0.0857
Entamoeba histolytica acyl-CoA synthetase, putative 0.0025 0.0126 0.0076
Echinococcus multilocularis ATP binding cassette subfamily B (MDR:TAP) 0.002 0.0082 0.0074
Schistosoma mansoni tubulin subunit beta 0.1039 1 1
Toxoplasma gondii aldose reductase, putative 0.0086 0.0719 0.0696
Entamoeba histolytica P-glycoprotein-2, putative 0.002 0.0082 0.0032
Trichomonas vaginalis aldo-keto reductase, putative 0.0025 0.0128 0.0104
Echinococcus multilocularis lamin 0.0017 0.0049 0.0041
Mycobacterium leprae Conserved hypothetical protein 0.0061 0.0478 0.1632
Loa Loa (eye worm) hypothetical protein 0.003 0.0181 0.0173
Schistosoma mansoni tubulin subunit beta 0.1039 1 1
Entamoeba histolytica Ran family GTPase 0.0042 0.0291 0.0242
Loa Loa (eye worm) hypothetical protein 0.0056 0.0436 0.0428
Onchocerca volvulus 0.0142 0.1271 0.2913
Leishmania major epsilon tubulin, putative 0.0567 0.5404 0.5393
Loa Loa (eye worm) hypothetical protein 0.002 0.0078 0.007
Echinococcus multilocularis aldehyde reductase 0.0061 0.0478 0.047
Giardia lamblia Beta tubulin 0.1039 1 1
Echinococcus granulosus tubulin alpha chain 0.0795 0.7628 0.7626
Brugia malayi Nuclear hormone receptor family member nhr-3 0.0027 0.0145 0.0137
Loa Loa (eye worm) hypothetical protein 0.0549 0.5232 0.5228
Onchocerca volvulus 0.0086 0.0719 0.1649
Schistosoma mansoni tubulin subunit delta 0.0246 0.2282 0.2276
Trypanosoma brucei ATP-binding cassette protein, putative 0.0017 0.0051 0.0026
Trypanosoma brucei importin beta-1 subunit, putative 0.0056 0.0436 0.0412
Trypanosoma brucei apurinic/apyrimidinic endonuclease, putative 0.0035 0.0231 0.0207
Trichomonas vaginalis ABC transporter, half transporter, putative 0.002 0.0082 0.0059
Giardia lamblia Gamma tubulin 0.0567 0.5404 0.5383
Loa Loa (eye worm) hypothetical protein 0.0014 0.0023 0.0015
Echinococcus multilocularis beta tubulin 0.1039 1 1
Leishmania major cytochrome p450-like protein 0.0108 0.094 0.0917
Echinococcus granulosus aldo keto reductase family 1 member B4 0.0086 0.0719 0.0711
Echinococcus multilocularis NADP dependent isocitrate dehydrogenase 0.0014 0.0025 0.0016
Loa Loa (eye worm) nuclear hormone receptor family member nhr-1 0.0027 0.0145 0.0137
Trichomonas vaginalis tubulin alpha-1 chain, putative 0.0321 0.3008 0.2992
Mycobacterium ulcerans cytochrome P450 140A5 Cyp140A5 0.0102 0.088 0.3715
Echinococcus multilocularis aldo keto reductase family 1, member B4 0.0086 0.0719 0.0711
Trichomonas vaginalis aldo-keto reductase, putative 0.0025 0.0128 0.0104
Loa Loa (eye worm) cytochrome P450 family protein 0.0124 0.1093 0.1085
Entamoeba histolytica hypothetical protein 0.0046 0.0332 0.0283
Trypanosoma brucei alpha tubulin 0.0795 0.7628 0.7622
Leishmania major alpha tubulin 0.0795 0.7628 0.7622
Giardia lamblia Delta tubulin 0.0246 0.2282 0.2246
Brugia malayi tubulin alpha-2 chain 0.0795 0.7628 0.7626
Mycobacterium ulcerans cytochrome P450 191A3 Cyp191A3 0.0102 0.088 0.3715
Loa Loa (eye worm) glutaminase 2 0.0246 0.2279 0.2273
Echinococcus granulosus hepatocyte nuclear factor 4 alpha 0.0027 0.0145 0.0137
Trypanosoma cruzi ATP-binding cassette protein, putative 0.0017 0.0051 0.0026
Entamoeba histolytica hypothetical protein 0.0028 0.0158 0.0108
Loa Loa (eye worm) alpha-tubulin 0.0795 0.7628 0.7626
Brugia malayi chromobox protein homolog 3 0.003 0.0181 0.0173
Echinococcus multilocularis lamin dm0 0.0017 0.0049 0.0041
Onchocerca volvulus 0.0013 0.0009 0.002
Echinococcus multilocularis arachidonate 5 lipoxygenase 0.0404 0.382 0.3814
Loa Loa (eye worm) tubulin alpha 2 0.0228 0.211 0.2103
Echinococcus granulosus multidrug resistance protein 1 0.0014 0.0024 0.0015
Loa Loa (eye worm) alpha-tubulin isotype 2 0.0549 0.5232 0.5228
Echinococcus multilocularis tubulin alpha 3 chain 0.0795 0.7628 0.7626
Echinococcus granulosus FTZ F1 alpha 0.0027 0.0145 0.0137
Toxoplasma gondii GTP-binding nuclear protein ran/tc4 0.0042 0.0291 0.0267
Leishmania major beta tubulin 0.1039 1 1
Echinococcus multilocularis multidrug resistance protein 1 0.0014 0.0024 0.0015
Leishmania major beta tubulin 0.1039 1 1
Brugia malayi calcium-independent alpha-latrotoxin receptor 2, putative 0.0056 0.0432 0.0424

Activities

No activities found for this compound.

Phenotypes

Whole-cell/tissue/organism interactions

We have no records of whole-cell/tissue assays done with this compound What does this mean?

Many chemical entities in TDR Targets come from high-throughput screenings with whole cells or tissue samples, and not all assayed compounds have been tested against a single a single target protein, probably because they get ruled out during screening process. Even if these compounds may have not been of interest in the original screening, they may come as interesting leads for other screening assays. Furthermore, we may be able to propose drug-target associations using chemical similarities and network patterns.

Annotated phenotypes:

We have no manually annotated phenotypes for this drug. What does this mean? / Care to help?
In TDR Targets, information about phenotypes that are caused by drugs, or by genetic manipulation of cells (e.g. gene knockouts or knockdowns) is manually curated from the literature. These descriptions help to describe the potential of the target for drug development. If no information is available for this gene or if the information is incomplete, this may mean that i) the papers containing this information either appeared after the curation effort for this organism was carried out or they were inadvertently missed by curators; or that ii) the curation effort for this organism has not yet started.
 
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External resources for this compound

Bibliographic References

No literature references available for this target.

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