Detailed information for compound 679857

Basic information

Technical information
  • TDR Targets ID: 679857
  • Name: methyl 4-[(Z)-[2,4-dioxo-3-(phenylmethyl)-1,3 -thiazolidin-5-ylidene]methyl]benzoate
  • MW: 353.392 | Formula: C19H15NO4S
  • H donors: 0 H acceptors: 3 LogP: 3.73 Rotable bonds: 5
    Rule of 5 violations (Lipinski): 1
  • SMILES: COC(=O)c1ccc(cc1)C=C1SC(=O)N(C1=O)Cc1ccccc1
  • InChi: 1S/C19H15NO4S/c1-24-18(22)15-9-7-13(8-10-15)11-16-17(21)20(19(23)25-16)12-14-5-3-2-4-6-14/h2-11H,12H2,1H3/b16-11-
  • InChiKey: UGWSEJMZUSGXPG-WJDWOHSUSA-N  


Substructure search Similarity search

Network

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Synonyms

  • methyl 4-[[2,4-dioxo-3-(phenylmethyl)-1,3-thiazolidin-5-ylidene]methyl]benzoate
  • methyl 4-[[2,4-dioxo-3-(phenylmethyl)thiazolidin-5-ylidene]methyl]benzoate
  • methyl 4-[(Z)-[2,4-dioxo-3-(phenylmethyl)thiazolidin-5-ylidene]methyl]benzoate
  • 4-[[2,4-dioxo-3-(phenylmethyl)-5-thiazolidinylidene]methyl]benzoic acid methyl ester
  • 4-[(Z)-[2,4-dioxo-3-(phenylmethyl)-5-thiazolidinylidene]methyl]benzoic acid methyl ester
  • 4-[[3-(benzyl)-2,4-diketo-thiazolidin-5-ylidene]methyl]benzoic acid methyl ester
  • 4-[(Z)-[3-(benzyl)-2,4-diketo-thiazolidin-5-ylidene]methyl]benzoic acid methyl ester
  • AN-989/40746961
  • ZINC02168202

Targets

Known targets for this compound

No curated genes were found associated with this compound

Predicted pathogen targets for this compound

By orthology
No druggable targets predicted by orthology data
By sequence similarity to non orthologous known druggable targets
No druggable targets predicted by sequence similarity
Obtained from network model

Ranking Plot

Putative Targets List

Species Potential target Raw Global Species
Echinococcus multilocularis cathepsin l cysteine peptidase 0.0018 0.0071 0.008
Loa Loa (eye worm) hypothetical protein 0.0019 0.0087 0.0081
Echinococcus multilocularis fmrfamide receptor 0.0019 0.0087 0.0098
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0068 0.0577 0.0589
Plasmodium falciparum SWIB/MDM2 domain-containing protein 0.0161 0.1516 0.6538
Trypanosoma cruzi mitochondrial RNA binding complex 1 subunit, putative 0.0057 0.0469 0.0475
Schistosoma mansoni peptide (allatostatin/somatostatin)-like receptor 0.0019 0.0087 0.0087
Brugia malayi RE15519p 0.0019 0.0087 0.0081
Loa Loa (eye worm) hypothetical protein 0.0019 0.0087 0.0081
Echinococcus granulosus neuropeptide receptor 0.0019 0.0087 0.0106
Echinococcus granulosus sodium and chloride dependent glycine 0.0118 0.1081 0.132
Loa Loa (eye worm) hypothetical protein 0.0033 0.0227 0.0221
Entamoeba histolytica Ras guanine nucleotide exchange factor, putative 0.0016 0.005 0.0081
Trichomonas vaginalis D-aminoacylase, putative 0.0041 0.0302 0.0302
Schistosoma mansoni norepinephrine/norepinephrine transporter 0.0118 0.1081 0.1081
Echinococcus multilocularis G protein coupled receptor 139 0.0019 0.0087 0.0098
Trypanosoma cruzi Acyl carrier protein, mitochondrial, putative 0.0014 0.003 0.0013
Loa Loa (eye worm) hypothetical protein 0.0019 0.0087 0.0081
Plasmodium vivax proline--tRNA ligase, putative 0.002 0.0089 0.0386
Leishmania major cathepsin L-like protease 0.0068 0.0577 0.0599
Brugia malayi AKH receptor 0.0019 0.0087 0.0081
Mycobacterium ulcerans acyl-CoA synthetase 0.0026 0.0153 0.0147
Echinococcus granulosus neuropeptide receptor A26 0.0019 0.0087 0.0106
Brugia malayi Melatonin receptor type 1A 0.0019 0.0087 0.0081
Brugia malayi sulfakinin receptor protein 0.0019 0.0087 0.0081
Echinococcus granulosus isocitrate dehydrogenase NAD 0.0011 0.0007 0.0008
Loa Loa (eye worm) hypothetical protein 0.0019 0.0087 0.0081
Echinococcus granulosus biogenic amine 5HT receptor 0.0019 0.0087 0.0106
Echinococcus granulosus hepatocyte nuclear factor 4 alpha 0.0011 0.0006 0.0008
Brugia malayi putative neuropeptide receptor 0.0019 0.0087 0.0081
Toxoplasma gondii calcium-dependent protein kinase CDPK2A 0.0019 0.0085 0.0484
Brugia malayi Zn-finger in Ran binding protein and others containing protein 0.0057 0.0469 0.0463
Mycobacterium ulcerans thioesterase TesA 0.0113 0.1036 0.103
Loa Loa (eye worm) hypothetical protein 0.0021 0.0102 0.0095
Onchocerca volvulus 0.0026 0.0155 0.0181
Schistosoma mansoni unc-13 (munc13) 0.0011 0.0007 0.0007
Toxoplasma gondii Sodium:neurotransmitter symporter family protein 0.0118 0.1081 0.6142
Mycobacterium ulcerans non-ribosomal peptide synthetase MbtF 0.0021 0.0107 0.01
Leishmania major prolyl-tRNA synthetase, putative,bifunctional aminoacyl-tRNA synthetase, putative 0.002 0.0089 0.0087
Plasmodium falciparum isocitrate dehydrogenase [NADP], mitochondrial 0.0094 0.0845 0.3642
Mycobacterium tuberculosis Polyketide synthase Pks13 0.0203 0.1945 0.4903
Mycobacterium ulcerans Type I modular polyketide synthase 0.0136 0.1265 0.1259
Schistosoma mansoni neuropeptide f receptor 76f 0.0019 0.0087 0.0087
Plasmodium falciparum cysteine proteinase falcipain 3 0.0018 0.0071 0.0307
Loa Loa (eye worm) pigment dispersing factor receptor c 0.0534 0.529 0.5287
Trichomonas vaginalis glucosylceramidase, putative 0.009 0.0798 0.0798
Echinococcus multilocularis calcium:calmodulin dependent protein kinase type 0.0019 0.0085 0.0096
Loa Loa (eye worm) hypothetical protein 0.0487 0.4817 0.4813
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0019 0.0087 0.0087
Mycobacterium leprae PHENOLPTHIOCEROL SYNTHESIS TYPE-I POLYKETIDE SYNTHASE PPSE 0.009 0.08 0.4091
Plasmodium vivax calcium-dependent protein kinase 3, putative 0.0019 0.0085 0.0368
Schistosoma mansoni sodium/chloride dependent transporter 0.0118 0.1081 0.1081
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0019 0.0087 0.0087
Trichomonas vaginalis ras GTP exchange factor, putative 0.0016 0.005 0.005
Entamoeba histolytica Ras guanine nucleotide exchange factor, putative 0.0016 0.005 0.0081
Entamoeba histolytica hypothetical protein 0.008 0.07 0.1136
Schistosoma mansoni hypothetical protein 0.0019 0.0087 0.0087
Brugia malayi Domain found in Dishevelled, Egl-10, and Pleckstrin family protein 0.0022 0.0114 0.0107
Echinococcus multilocularis neuropeptide receptor A26 0.0019 0.0087 0.0098
Onchocerca volvulus Cathepsin F homolog 0.0018 0.0071 0.0079
Loa Loa (eye worm) hypothetical protein 0.0693 0.6901 0.6899
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0068 0.0577 0.0589
Trichomonas vaginalis conserved hypothetical protein 0.0041 0.0305 0.0305
Schistosoma mansoni hypothetical protein 0.0083 0.0729 0.0729
Mycobacterium tuberculosis Probable peptide synthetase Nrp (peptide synthase) 0.0021 0.0107 0.0253
Loa Loa (eye worm) TYRA-2 protein 0.0019 0.0087 0.0081
Loa Loa (eye worm) heterochromatin protein 1 0.0059 0.0491 0.0485
Plasmodium vivax vivapain-2 0.0018 0.0071 0.0307
Echinococcus multilocularis regulator of G protein signaling 7 0.0022 0.0114 0.0128
Loa Loa (eye worm) hypothetical protein 0.0019 0.0087 0.0081
Mycobacterium ulcerans fatty-acid-CoA ligase FadD9 0.0015 0.0041 0.0034
Brugia malayi serine/threonine-protein kinase plk-2 0.0619 0.6156 0.6154
Trypanosoma cruzi isocitrate dehydrogenase [NADP], mitochondrial precursor, putative 0.0094 0.0845 0.087
Echinococcus granulosus regulator of G protein signaling 7 0.0022 0.0114 0.0139
Trichomonas vaginalis CAMK family protein kinase 0.0619 0.6156 0.6156
Loa Loa (eye worm) hypothetical protein 0.0118 0.1081 0.1075
Brugia malayi GnHR receptor homolog 0.0019 0.0087 0.0081
Brugia malayi hypothetical protein 0.0019 0.0087 0.0081
Schistosoma mansoni sodium-dependent amino acid transporter 0.0118 0.1081 0.1081
Onchocerca volvulus 0.0019 0.0087 0.0099
Entamoeba histolytica hypothetical protein 0.008 0.07 0.1136
Schistosoma mansoni Isocitrate dehydrogenase [NAD] subunit gamma mitochondrial 0.0011 0.0007 0.0007
Echinococcus multilocularis FTZ F1 alpha 0.0011 0.0006 0.0007
Schistosoma mansoni glutaminase 0.0999 1 1
Brugia malayi beta-lactamase family protein 0.0041 0.0302 0.0296
Trichomonas vaginalis conserved hypothetical protein 0.0033 0.0227 0.0227
Trichomonas vaginalis CAMK family protein kinase 0.0619 0.6156 0.6156
Toxoplasma gondii SWIB/MDM2 domain-containing protein 0.0161 0.1516 0.8615
Leishmania major 4-coumarate:coa ligase-like protein 0.0026 0.0153 0.0154
Echinococcus multilocularis regulator of G protein signaling 7 0.0022 0.0114 0.0128
Schistosoma mansoni amine GPCR 0.0019 0.0087 0.0087
Schistosoma mansoni adenoreceptor 0.0019 0.0087 0.0087
Onchocerca volvulus Heterochromatin protein 1 homolog 0.0036 0.0253 0.0301
Schistosoma mansoni tar DNA-binding protein 0.0129 0.1198 0.1198
Loa Loa (eye worm) hypothetical protein 0.0019 0.0087 0.0081
Trichomonas vaginalis conserved hypothetical protein 0.0017 0.0067 0.0067
Schistosoma mansoni dishevelled 0.0022 0.0114 0.0114
Mycobacterium tuberculosis Probable multifunctional mycocerosic acid synthase membrane-associated Mas 0.0144 0.1351 0.34
Echinococcus granulosus calcium:calmodulin dependent protein kinase type 0.0019 0.0085 0.0104
Loa Loa (eye worm) CAMK/CAMK2 protein kinase 0.0019 0.0085 0.0079
Echinococcus multilocularis COUP TF:Svp nuclear hormone receptor 0.0011 0.0006 0.0007
Schistosoma mansoni RAR-like nuclear receptor 0.0011 0.0006 0.0006
Echinococcus granulosus vesicular acetylcholine transporter 0.0821 0.8191 1
Trypanosoma cruzi cysteine peptidase, putative 0.0068 0.0577 0.0589
Trichomonas vaginalis ras GTP exchange factor, son of sevenless, putative 0.0016 0.005 0.005
Brugia malayi Zn-finger in Ran binding protein and others containing protein 0.0057 0.0469 0.0463
Echinococcus multilocularis beta LACTamase domain containing family member 0.0041 0.0302 0.0341
Trichomonas vaginalis penicillin-binding protein, putative 0.0041 0.0302 0.0302
Trypanosoma cruzi PAB1-binding protein , putative 0.0185 0.176 0.1832
Loa Loa (eye worm) ctsf protein 0.0018 0.0071 0.0065
Entamoeba histolytica acyl-CoA synthetase, putative 0.0026 0.0153 0.0249
Loa Loa (eye worm) acyl carrier protein 0.0014 0.003 0.0023
Entamoeba histolytica Ras guanine nucleotide exchange factor, putative 0.0016 0.005 0.0081
Loa Loa (eye worm) hypothetical protein 0.0019 0.0087 0.0081
Plasmodium vivax SET domain protein, putative 0.0052 0.042 0.1809
Entamoeba histolytica protein kinase, putative 0.0019 0.0085 0.0138
Onchocerca volvulus Ubiquitin thioesterase ZRANB1 homolog 0.0057 0.0469 0.0565
Plasmodium vivax calcium-dependent protein kinase 1, putative 0.0019 0.0085 0.0368
Mycobacterium leprae PROBABLE FATTY-ACID-CoA LIGASE FADD2 (FATTY-ACID-CoA SYNTHETASE) (FATTY-ACID-CoA SYNTHASE) 0.0026 0.0153 0.0756
Mycobacterium ulcerans fusion of enoyl-CoA hydratase, EchA21 and lipase, LipE 0.0041 0.0302 0.0295
Plasmodium falciparum cysteine proteinase falcipain 2b 0.0018 0.0071 0.0307
Leishmania major glucose transporter, lmgt1 0.0017 0.0067 0.0063
Mycobacterium leprae Probable lipase LipE 0.0041 0.0302 0.1522
Loa Loa (eye worm) hypothetical protein 0.0365 0.3582 0.3578
Echinococcus multilocularis sodium and chloride dependent glycine 0.0118 0.1081 0.122
Echinococcus granulosus neuropeptide Y receptor 0.0019 0.0087 0.0106
Mycobacterium leprae PHENOLPTHIOCEROL SYNTHESIS TYPE-I POLYKETIDE SYNTHASE PPSC 0.0144 0.1351 0.6934
Echinococcus multilocularis serine:threonine protein kinase PLK1 0.0619 0.6156 0.6946
Schistosoma mansoni sodium/chloride dependent transporter 0.0121 0.1112 0.1112
Schistosoma mansoni lysyl-tRNA synthetase 0.0013 0.0018 0.0018
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0068 0.0577 0.0589
Loa Loa (eye worm) hypothetical protein 0.0019 0.0087 0.0081
Toxoplasma gondii type I fatty acid synthase 0.0021 0.0102 0.0579
Plasmodium vivax lysine--tRNA ligase, putative 0.0013 0.0018 0.0076
Onchocerca volvulus 0.0018 0.0071 0.0079
Loa Loa (eye worm) hypothetical protein 0.0019 0.0087 0.0081
Schistosoma mansoni biogenic amine (octopamine/dopamine) receptor 0.0019 0.0087 0.0087
Echinococcus multilocularis calcium:calmodulin dependent protein kinase type 0.0019 0.0085 0.0096
Loa Loa (eye worm) hypothetical protein 0.0019 0.0087 0.0081
Echinococcus granulosus g protein linked acetylcholine receptor gar 2a 0.0019 0.0087 0.0106
Entamoeba histolytica Ras guanine nucleotide exchange factor, putative 0.0016 0.005 0.0081
Echinococcus multilocularis segment polarity protein dishevelled 0.0022 0.0114 0.0128
Loa Loa (eye worm) hypothetical protein 0.0041 0.0302 0.0296
Toxoplasma gondii calcium-dependent protein kinase CDPK3 0.0019 0.0085 0.0484
Echinococcus granulosus diuretic hormone 44 receptor GPRdih2 0.0169 0.1599 0.1952
Brugia malayi AMP-binding enzyme family protein 0.0135 0.1252 0.1246
Echinococcus granulosus calcium:calmodulin dependent protein kinase type 0.0019 0.0085 0.0104
Loa Loa (eye worm) hypothetical protein 0.0012 0.0012 0.0005
Mycobacterium ulcerans fatty-acid-CoA ligase 0.0019 0.0087 0.008
Echinococcus multilocularis GPCR, family 2 0.0169 0.1599 0.1805
Echinococcus multilocularis rhodopsin orphan GPCR 0.0019 0.0087 0.0098
Echinococcus multilocularis sodium dependent neurotransmitter transporter 0.0118 0.1081 0.122
Echinococcus granulosus 3 oxoacyl acyl carrier protein synthase 0.0034 0.0236 0.0288
Chlamydia trachomatis acyl carrier protein 0.0014 0.003 0.0081
Brugia malayi Cathepsin L-like precursor 0.0018 0.0071 0.0065
Brugia malayi Cathepsin L-like precursor 0.0018 0.0071 0.0065
Echinococcus granulosus histone lysine methyltransferase setb 0.0052 0.042 0.0512
Plasmodium vivax hexose transporter 0.0056 0.0458 0.1976
Brugia malayi cathepsin L-like precursor 0.0012 0.0012 0.0005
Loa Loa (eye worm) norepinephrine transporter 0.0693 0.6901 0.6899
Brugia malayi Sodium:neurotransmitter symporter family protein 1, putative 0.0118 0.1081 0.1075
Schistosoma mansoni retinoic acid receptor RXR 0.0011 0.0006 0.0006
Loa Loa (eye worm) hypothetical protein 0.0017 0.0061 0.0055
Loa Loa (eye worm) hypothetical protein 0.0019 0.0087 0.0081
Schistosoma mansoni growth hormone secretagogue receptor 0.0019 0.0087 0.0087
Onchocerca volvulus Dopamine\/Ecdysteroid receptor homolog 0.0019 0.0087 0.0099
Brugia malayi Dopamine receptor protein 2 0.0019 0.0087 0.0081
Onchocerca volvulus 0.0019 0.0087 0.0099
Toxoplasma gondii hypothetical protein 0.0118 0.1081 0.6142
Echinococcus multilocularis vesicular acetylcholine transporter 0.0821 0.8191 0.9243
Schistosoma mansoni tar DNA-binding protein 0.0129 0.1198 0.1198
Toxoplasma gondii hypothetical protein 0.0022 0.0114 0.0646
Trypanosoma cruzi hexose transporter, putative 0.0017 0.0067 0.0052
Loa Loa (eye worm) hypothetical protein 0.0018 0.0071 0.0065
Echinococcus multilocularis diuretic hormone 44 receptor GPRdih2 0.0169 0.1599 0.1805
Trichomonas vaginalis chromobox protein, putative 0.0036 0.0253 0.0253
Trichomonas vaginalis set domain proteins, putative 0.0415 0.4084 0.4084
Trypanosoma cruzi polo-like protein kinase, putative 0.0619 0.6156 0.6454
Schistosoma mansoni glucose transport protein 0.0056 0.0458 0.0458
Mycobacterium ulcerans polyketide synthase Pks13 0.0203 0.1945 0.1939
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0019 0.0087 0.0087
Mycobacterium tuberculosis Probable polyketide synthase Pks15 0.0055 0.0447 0.1113
Brugia malayi Heterochromatin protein 1 0.0059 0.0491 0.0485
Brugia malayi putative neuropeptide receptor NPR1 0.0019 0.0087 0.0081
Echinococcus granulosus g-protein coupled receptor 0.0019 0.0087 0.0106
Brugia malayi beta-lactamase 0.0041 0.0302 0.0296
Trypanosoma cruzi beta-ketoacyl synthase family protein, putative 0.0034 0.0236 0.023
Mycobacterium leprae Probable fatty-acid-CoA ligase FadD9 (fatty-acid-CoA synthetase) (fatty-acid-CoA synthase) 0.0015 0.0041 0.0174
Loa Loa (eye worm) O-glycosyl hydrolase family 30 protein 0.0137 0.1273 0.1267
Trichomonas vaginalis chromobox protein, putative 0.0059 0.0491 0.0491
Mycobacterium tuberculosis Probable acyl carrier protein AcpA (ACP) 0.0014 0.003 0.0058
Trypanosoma cruzi hypothetical protein, conserved 0.0057 0.0469 0.0475
Loa Loa (eye worm) hypothetical protein 0.0041 0.0302 0.0296
Echinococcus granulosus solute carrier family 2 facilitated glucose 0.0056 0.0458 0.056
Schistosoma mansoni isocitrate dehydrogenase 0.0011 0.0007 0.0007
Trichomonas vaginalis conserved hypothetical protein 0.0161 0.1516 0.1516
Schistosoma mansoni histone-lysine n-methyltransferase setb1 0.0052 0.042 0.042
Loa Loa (eye worm) acyl carrier protein 0.0062 0.0523 0.0517
Echinococcus multilocularis tar DNA binding protein 0.0129 0.1198 0.1352
Echinococcus granulosus neuropeptide Y receptor 0.0019 0.0087 0.0106
Echinococcus granulosus lysyl tRNA synthetase 0.0013 0.0018 0.0022
Brugia malayi G protein-coupled receptor F59B2.13 0.0019 0.0087 0.0081
Onchocerca volvulus 0.0019 0.0087 0.0099
Plasmodium vivax SWIB/MDM2 domain-containing protein, putative 0.0161 0.1516 0.6538
Brugia malayi Sodium:neurotransmitter symporter family protein 0.0118 0.1081 0.1075
Schistosoma mansoni cathepsin F (C01 family) 0.0018 0.0071 0.0071
Onchocerca volvulus 0.0019 0.0087 0.0099
Trypanosoma cruzi cysteine peptidase, clan CA, family C1, cathepsin L-like, putative 0.0062 0.0518 0.0526
Trypanosoma cruzi hypothetical protein, conserved 0.0041 0.0302 0.0299
Mycobacterium tuberculosis Probable lipase LipD 0.0041 0.0302 0.0746
Brugia malayi Methyltransferase-like protein 4 0.0041 0.0305 0.0299
Brugia malayi regulator of G-protein signaling egl-10 0.0022 0.0114 0.0107
Giardia lamblia Prolyl-tRNA synthetase 0.0017 0.0061 0.01
Toxoplasma gondii cell-cycle-associated protein kinase MAPK, putative 0.0093 0.0828 0.4705
Echinococcus multilocularis biogenic amine (5HT) receptor 0.0019 0.0087 0.0098
Onchocerca volvulus 0.0057 0.0469 0.0565
Toxoplasma gondii beta-ketoacyl synthase, N-terminal domain-containing protein 0.0088 0.0782 0.4446
Schistosoma mansoni sodium-dependent neurotransmitter transporter 0.0118 0.1081 0.1081
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0018 0.0071 0.0071
Onchocerca volvulus 0.0135 0.1252 0.1522
Loa Loa (eye worm) hypothetical protein 0.0019 0.0087 0.0081
Entamoeba histolytica serine/threonine protein kinase, putative 0.0619 0.6156 1
Echinococcus multilocularis rap guanine nucleotide exchange factor 6 0.0016 0.005 0.0056
Trypanosoma cruzi hexose transporter 0.0017 0.0067 0.0052
Echinococcus granulosus serine:threonine protein kinase PLK1 0.0619 0.6156 0.7516
Echinococcus multilocularis zinc finger protein Ran binding 0.0057 0.0469 0.0529
Echinococcus granulosus sex peptide receptor 0.0019 0.0087 0.0106
Mycobacterium ulcerans hypothetical protein 0.0026 0.0153 0.0147
Trichomonas vaginalis Clan CA, family C1, papain-like cysteine peptidase 0.0018 0.0071 0.0071
Trichomonas vaginalis chromobox protein, putative 0.0059 0.0491 0.0491
Loa Loa (eye worm) hypothetical protein 0.0693 0.6901 0.6899
Giardia lamblia Kinase, PLK 0.0619 0.6156 1
Echinococcus granulosus nuclear receptor 2DBD gamma 0.0011 0.0006 0.0008
Brugia malayi hypothetical protein 0.0019 0.0087 0.0081
Trichomonas vaginalis ras GTP exchange factor, putative 0.0016 0.005 0.005
Mycobacterium ulcerans non-ribosomal peptide synthetase MbtE 0.0021 0.0107 0.01
Brugia malayi RNA binding protein 0.0129 0.1198 0.1193
Schistosoma mansoni amine GPCR 0.0019 0.0087 0.0087
Plasmodium vivax isocitrate dehydrogenase [NADP], mitochondrial, putative 0.0094 0.0845 0.3642
Echinococcus granulosus sodium and chloride dependent glycine 0.0118 0.1081 0.132
Echinococcus multilocularis rhodopsin orphan GPCR 0.0019 0.0087 0.0098
Loa Loa (eye worm) hypothetical protein 0.0019 0.0087 0.0081
Onchocerca volvulus 0.0019 0.0087 0.0099
Loa Loa (eye worm) hypothetical protein 0.0118 0.1081 0.1075
Mycobacterium ulcerans esterase/lipase LipP 0.0041 0.0302 0.0295
Trypanosoma cruzi cysteine peptidase, putative 0.0068 0.0577 0.0589
Loa Loa (eye worm) hypothetical protein 0.0118 0.1081 0.1075
Schistosoma mansoni hypothetical protein 0.008 0.07 0.07
Schistosoma mansoni nuclear hormone receptor 0.0011 0.0006 0.0006
Entamoeba histolytica hypothetical protein 0.008 0.07 0.1136
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0012 0.0012 0.0012
Trichomonas vaginalis lysyl-tRNA synthetase, putative 0.0013 0.0018 0.0018
Echinococcus multilocularis neuropeptide FF receptor 2 0.0019 0.0087 0.0098
Schistosoma mansoni hypothetical protein 0.0014 0.003 0.003
Schistosoma mansoni transcription factor LCR-F1 0.008 0.07 0.07
Plasmodium vivax calcium-dependent protein kinase, putative 0.0019 0.0085 0.0368
Onchocerca volvulus Fatty acid synthase homolog 0.0245 0.2368 0.2885
Mycobacterium leprae Probable multifunctional mycocerosic acid synthase membrane associated enzyme Mas 0.0144 0.1351 0.6934
Loa Loa (eye worm) hypothetical protein 0.0153 0.1439 0.1433
Echinococcus multilocularis rhodopsin orphan GPCR 0.0019 0.0087 0.0098
Leishmania major glucose transporter/membrane transporter D2, putative 0.0017 0.0067 0.0063
Mycobacterium tuberculosis Conserved protein 0.0041 0.0302 0.0746
Echinococcus multilocularis Protein son of sevenless 0.0016 0.005 0.0056
Mycobacterium tuberculosis Peptide synthetase MbtE (peptide synthase) 0.0021 0.0107 0.0253
Loa Loa (eye worm) hypothetical protein 0.0019 0.0087 0.0081
Loa Loa (eye worm) neuropeptide F receptor 0.0019 0.0087 0.0081
Loa Loa (eye worm) calcium/calmodulin-dependent protein kinase ID 0.0019 0.0085 0.0079
Brugia malayi N-terminal motif family protein 0.0016 0.005 0.0043
Schistosoma mansoni thyroid hormone receptor 0.0011 0.0006 0.0006
Loa Loa (eye worm) hypothetical protein 0.0026 0.0153 0.0147
Brugia malayi larval opioid receptor 0.0019 0.0087 0.0081
Echinococcus multilocularis peptide (allatostatin:somatostatin) 0.0019 0.0087 0.0098
Echinococcus multilocularis g-protein coupled receptor 0.0019 0.0087 0.0098
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0018 0.0071 0.0071
Mycobacterium leprae Probable fatty-acid-CoA synthetase FadD22 (fatty-acid-CoA ligase) (fatty-acid-CoA synthase) 0.0021 0.0107 0.0516
Mycobacterium tuberculosis Phenolpthiocerol synthesis type-I polyketide synthase PpsA 0.0136 0.1265 0.3184
Echinococcus multilocularis rap guanine nucleotide exchange factor 1 0.0016 0.005 0.0056
Echinococcus granulosus ras GTP exchange factor 0.0016 0.005 0.0061
Toxoplasma gondii AMP-binding enzyme domain-containing protein 0.007 0.0596 0.3388
Trichomonas vaginalis glucose transporter, putative 0.0017 0.0067 0.0067
Mycobacterium tuberculosis Probable esterase LipL 0.0041 0.0302 0.0746
Echinococcus granulosus NADH dehydrogenase 0.0014 0.003 0.0036
Toxoplasma gondii protein kinase G AGC kinase family member PKG 0.0013 0.002 0.0113
Echinococcus granulosus serotonin receptor 0.0019 0.0087 0.0106
Schistosoma mansoni sodium/chloride dependent transporter 0.0693 0.6901 0.6901
Loa Loa (eye worm) hypothetical protein 0.0019 0.0087 0.0081
Echinococcus multilocularis dro:myosuppressin receptor 0.0019 0.0087 0.0098
Loa Loa (eye worm) hypothetical protein 0.0016 0.005 0.0043
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0018 0.0071 0.0071
Schistosoma mansoni retinoid-x-receptor (RXR) 0.0011 0.0006 0.0006
Onchocerca volvulus 0.0019 0.0087 0.0099
Mycobacterium tuberculosis Phenyloxazoline synthase MbtB (phenyloxazoline synthetase) 0.0135 0.1252 0.315
Echinococcus multilocularis Upstream activation factor subunit UAF30 0.0161 0.1516 0.1711
Schistosoma mansoni hypothetical protein 0.0019 0.0087 0.0087
Mycobacterium tuberculosis Conserved hypothetical protein 0.0014 0.003 0.0058
Loa Loa (eye worm) hypothetical protein 0.0019 0.0087 0.0081
Brugia malayi DIX domain containing protein 0.0022 0.0114 0.0107
Brugia malayi Pre-SET motif family protein 0.0364 0.3575 0.3571
Echinococcus multilocularis neuropeptide Y receptor 0.0019 0.0087 0.0098
Leishmania major hypothetical protein, conserved 0.0057 0.0469 0.0486
Trypanosoma brucei mitochondrial RNA binding complex 1 subunit 0.0057 0.0469 0.0475
Loa Loa (eye worm) 5-hydroxytryptamine 2C receptor 0.0019 0.0087 0.0081
Mycobacterium tuberculosis Probable fatty acid synthase Fas (fatty acid synthetase) 0.0043 0.0323 0.0799
Mycobacterium ulcerans phenyloxazoline synthase MbtB 0.0021 0.0107 0.01
Leishmania major glucose transporter, lmgt3 0.0017 0.0067 0.0063
Echinococcus granulosus calcium:calmodulin dependent protein kinase type 0.0019 0.0085 0.0104
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0018 0.0071 0.0071
Schistosoma mansoni guanine-nucleotide-exchange-factor 0.0016 0.005 0.005
Plasmodium vivax amine transporter, putative 0.0118 0.1081 0.4661
Echinococcus granulosus Nuclear pore complex protein Nup153 0.0057 0.0469 0.0573
Trypanosoma cruzi isocitrate dehydrogenase, putative 0.0094 0.0845 0.087
Loa Loa (eye worm) isocitrate dehydrogenase 0.0094 0.0845 0.0839
Mycobacterium ulcerans acyl-CoA synthetase 0.0026 0.0153 0.0147
Entamoeba histolytica Ras guanine nucleotide exchange factor, putative 0.0016 0.005 0.0081
Echinococcus multilocularis tm gpcr rhodopsin gpcr rhodopsin superfamily 0.0019 0.0087 0.0098
Schistosoma mansoni biogenic amine receptor 0.0019 0.0087 0.0087
Loa Loa (eye worm) hypothetical protein 0.0017 0.0061 0.0055
Mycobacterium leprae conserved hypothetical protein 0.0041 0.0302 0.1522
Plasmodium falciparum calcium-dependent protein kinase 3 0.0019 0.0085 0.0368
Onchocerca volvulus 0.0062 0.0518 0.0625
Echinococcus granulosus G protein coupled 5 hydroxytryptamine receptor 0.0019 0.0087 0.0106
Onchocerca volvulus 0.0016 0.005 0.0053
Trichomonas vaginalis CAMK family protein kinase 0.0307 0.2998 0.2998
Brugia malayi AMP-binding enzyme family protein 0.0026 0.0153 0.0147
Brugia malayi glutaminase DH11.1 0.0999 1 1
Schistosoma mansoni steroid hormone receptor ad4bp 0.0011 0.0006 0.0006
Mycobacterium tuberculosis Probable esterase/lipase LipP 0.0041 0.0302 0.0746
Leishmania major isocitrate dehydrogenase [NADP], mitochondrial precursor, putative 0.0094 0.0845 0.088
Echinococcus multilocularis tachykinin peptides receptor 99D 0.0019 0.0087 0.0098
Loa Loa (eye worm) Sodium:neurotransmitter symporter family protein 0.0118 0.1081 0.1075
Schistosoma mansoni hypothetical protein 0.0056 0.0458 0.0458
Schistosoma mansoni glucose transport protein 0.0056 0.0458 0.0458
Trichomonas vaginalis glucosylceramidase, putative 0.0094 0.0847 0.0847
Mycobacterium tuberculosis Probable polyketide synthase Pks17 0.0033 0.0227 0.0556
Schistosoma mansoni fyve finger-containing phosphoinositide kinase fyv1 0.0022 0.0114 0.0114
Echinococcus granulosus NADP dependent isocitrate dehydrogenase 0.0094 0.0845 0.1031
Brugia malayi Phosphopantetheine attachment site family protein 0.0014 0.003 0.0023
Leishmania major cysteine peptidase A (CPA) 0.0018 0.0071 0.0068
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0012 0.0012 0.0012
Trichomonas vaginalis conserved hypothetical protein 0.0033 0.0227 0.0227
Trypanosoma brucei C-8 sterol isomerase, putative 0.0953 0.9528 1
Trichomonas vaginalis D-aminoacylase, putative 0.0041 0.0302 0.0302
Brugia malayi hypothetical protein 0.0118 0.1081 0.1075
Echinococcus granulosus chromobox protein 1 0.0059 0.0491 0.06
Trypanosoma cruzi hypothetical protein, conserved 0.0057 0.0469 0.0475
Mycobacterium tuberculosis Probable isocitrate dehydrogenase [NADP] Icd1 (oxalosuccinate decarboxylase) (IDH) (NADP+-specific ICDH) (IDP) 0.0094 0.0845 0.212
Brugia malayi Cathepsin L-like precursor 0.0018 0.0071 0.0065
Mycobacterium ulcerans non-ribosomal peptide synthetase 0.0015 0.0041 0.0034
Schistosoma mansoni neuropeptide receptor 0.0019 0.0087 0.0087
Mycobacterium leprae conserved hypothetical protein 0.0014 0.003 0.0118
Toxoplasma gondii LsmAD domain-containing protein 0.0185 0.176 1
Leishmania major lysyl-tRNA synthetase, putative 0.0013 0.0018 0.0011
Schistosoma mansoni peptide (allatostatin)-like receptor 0.0019 0.0087 0.0087
Echinococcus multilocularis thyroid hormone receptor alpha 0.0011 0.0006 0.0007
Mycobacterium tuberculosis Probable conserved lipoprotein 0.0041 0.0302 0.0746
Loa Loa (eye worm) Sodium:neurotransmitter symporter family protein 0.0118 0.1081 0.1075
Echinococcus granulosus serotonin transporter 0.0693 0.6901 0.8425
Brugia malayi Dopamine receptor protein 1, putative (partial) 0.0019 0.0087 0.0081
Echinococcus granulosus Protein son of sevenless 0.0016 0.005 0.0061
Mycobacterium tuberculosis Probable fatty-acid-CoA ligase FadD7 (fatty-acid-CoA synthetase) (fatty-acid-CoA synthase) 0.0018 0.0076 0.0176
Onchocerca volvulus 0.0018 0.0071 0.0079
Echinococcus multilocularis ring and YY1 binding protein 0.0057 0.0469 0.0529
Trichomonas vaginalis glucosylceramidase, putative 0.0137 0.1273 0.1273
Loa Loa (eye worm) sugar transporter 0.0056 0.0458 0.0452
Loa Loa (eye worm) hypothetical protein 0.0438 0.4324 0.4321
Entamoeba histolytica acyl-coA synthetase, putative 0.0026 0.0153 0.0249
Giardia lamblia Methyltransferase like 2 0.0041 0.0305 0.0495
Echinococcus multilocularis somatostatin receptor 0.0019 0.0087 0.0098
Plasmodium vivax vivapain-2 0.0018 0.0071 0.0307
Schistosoma mansoni cathepsin F (C01 family) 0.0012 0.0012 0.0012
Entamoeba histolytica Ras guanine nucleotide exchange factor, putative 0.0016 0.005 0.0081
Brugia malayi Serotonin receptor 0.0019 0.0087 0.0081
Brugia malayi Serotonin/octopamine receptor family protein 7 0.0019 0.0087 0.0081
Trichomonas vaginalis Clan CA, family C1, papain-like cysteine peptidase 0.0018 0.0071 0.0071
Mycobacterium ulcerans lysyl-tRNA synthetase 0.0013 0.0018 0.0011
Trypanosoma brucei glucose transporter, putative 0.0017 0.0067 0.0052
Loa Loa (eye worm) transcription factor SMAD2 0.0127 0.1175 0.117
Brugia malayi latrophilin 2 splice variant baaae 0.0365 0.3582 0.3578
Toxoplasma gondii isocitrate dehydrogenase 0.0094 0.0845 0.4799
Echinococcus granulosus uncharacterized sodium dependent transporter 0.0118 0.1081 0.132
Trypanosoma cruzi C-8 sterol isomerase, putative 0.0953 0.9528 1
Loa Loa (eye worm) hypothetical protein 0.0019 0.0087 0.0081
Schistosoma mansoni neuropeptide receptor 0.0019 0.0087 0.0087
Echinococcus multilocularis cGMP dependent protein kinase 1 0.0013 0.002 0.0022
Plasmodium falciparum lysine--tRNA ligase 0.0013 0.0018 0.0076
Echinococcus multilocularis isocitrate dehydrogenase (NAD+) 0.0011 0.0007 0.0008
Brugia malayi Cam kinase protein 1 0.0019 0.0085 0.0079
Plasmodium falciparum cGMP-dependent protein kinase 0.0013 0.002 0.0086
Schistosoma mansoni sodium-dependent neurotransmitter transporter 0.0118 0.1081 0.1081
Echinococcus multilocularis microtubule associated protein 2 0.0674 0.6708 0.7569
Mycobacterium ulcerans phenolpthiocerol synthesis type-I polyketide synthase PpsA 0.0109 0.0997 0.099
Onchocerca volvulus 0.0118 0.1081 0.1313
Trichomonas vaginalis sugar transporter, putative 0.0017 0.0067 0.0067
Echinococcus multilocularis isocitrate dehydrogenase (NAD) subunit 0.0011 0.0007 0.0008
Echinococcus multilocularis calcium dependent protein kinase 0.0016 0.0054 0.0061
Trichomonas vaginalis conserved hypothetical protein 0.0017 0.0067 0.0067
Onchocerca volvulus 0.0019 0.0087 0.0099
Leishmania major cathepsin L-like protease 0.0018 0.0071 0.0068
Loa Loa (eye worm) beta-ketoacyl synthase domain-containing protein 0.0034 0.0236 0.023
Loa Loa (eye worm) hypothetical protein 0.0019 0.0087 0.0081
Mycobacterium tuberculosis Conserved protein 0.0041 0.0302 0.0746
Brugia malayi beta-lactamase family protein 0.0041 0.0302 0.0296
Echinococcus granulosus calcium:calmodulin dependent protein kinase type 1 0.0019 0.0085 0.0104
Entamoeba histolytica hypothetical protein 0.0016 0.005 0.0081
Schistosoma mansoni FTZ-F1 nuclear receptor-like protein 0.0011 0.0006 0.0006
Echinococcus multilocularis fmrfamide receptor 0.0019 0.0087 0.0098
Plasmodium vivax hypothetical protein, conserved 0.0118 0.1081 0.4661
Echinococcus multilocularis Pleckstrin G protein, interacting region 0.0022 0.0114 0.0128
Trichomonas vaginalis esterase, putative 0.0041 0.0302 0.0302
Toxoplasma gondii 3-oxoacyl-acyl-carrier protein synthase I/II, putative 0.0034 0.0236 0.1341
Schistosoma mansoni TRABID protein (C64 family) 0.0057 0.0469 0.0469
Schistosoma mansoni regulator of G protein signaling 0.0022 0.0114 0.0114
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0018 0.0071 0.0071
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0018 0.0071 0.0071
Echinococcus multilocularis orexin receptor type 2 0.0019 0.0087 0.0098
Echinococcus granulosus Zinc finger RanBP2 type 0.0057 0.0469 0.0573
Trypanosoma cruzi PAB1-binding protein , putative 0.0185 0.176 0.1832
Mycobacterium tuberculosis Probable fatty-acid-CoA ligase FadD35 (fatty-acid-CoA synthetase) (fatty-acid-CoA synthase) 0.0018 0.0076 0.0176
Mycobacterium tuberculosis Possible conserved lipoprotein LpqK 0.0041 0.0302 0.0746
Echinococcus multilocularis solute carrier family 2 facilitated glucose 0.0056 0.0458 0.0517
Echinococcus multilocularis G protein coupled 5 hydroxytryptamine receptor 0.0019 0.0087 0.0098
Schistosoma mansoni opsin-like receptor 0.0019 0.0087 0.0087
Echinococcus multilocularis isocitrate dehydrogenase 2 (NADP+) 0.0094 0.0845 0.0953
Schistosoma mansoni hypothetical protein 0.0169 0.1599 0.1599
Echinococcus granulosus allatostatin A receptor 0.0019 0.0087 0.0106
Schistosoma mansoni hypothetical protein 0.0161 0.1516 0.1516
Brugia malayi AMP-binding enzyme family protein 0.0043 0.0324 0.0318
Entamoeba histolytica hypothetical protein 0.008 0.07 0.1136
Trypanosoma brucei glucose transporter, putative 0.0017 0.0067 0.0052
Brugia malayi Egg laying defective protein 4 0.0013 0.002 0.0013
Brugia malayi Cathepsin L-like precursor 0.0012 0.0012 0.0005
Onchocerca volvulus 0.0057 0.0469 0.0565
Schistosoma mansoni biogenic amine receptor 0.0019 0.0087 0.0087
Toxoplasma gondii isocitrate dehydrogenase 0.0094 0.0845 0.4799
Onchocerca volvulus 0.0041 0.0302 0.0361
Onchocerca volvulus Segment polarity protein dishevelled homolog 0.0022 0.0114 0.0131
Schistosoma mansoni vesicular acetylcholine transporter 0.0821 0.8191 0.8191
Schistosoma mansoni serine/threonine protein kinase 0.0013 0.002 0.002
Schistosoma mansoni camp-dependent rap1 guanine-nucleotide exchange factor 0.0015 0.0042 0.0042
Loa Loa (eye worm) beta-lactamase 0.0041 0.0302 0.0296
Entamoeba histolytica Ras guanine nucleotide exchange factor, putative 0.0016 0.005 0.0081
Brugia malayi RasGEF domain containing protein 0.0016 0.005 0.0043
Loa Loa (eye worm) MH2 domain-containing protein 0.0127 0.1175 0.117
Echinococcus granulosus neuropeptide FF receptor 2 0.0019 0.0087 0.0106
Plasmodium falciparum transporter, putative 0.0118 0.1081 0.4661
Schistosoma mansoni family S12 unassigned peptidase (S12 family) 0.0041 0.0302 0.0302
Loa Loa (eye worm) pre-SET domain-containing protein family protein 0.0364 0.3575 0.3571
Loa Loa (eye worm) hypothetical protein 0.0041 0.0302 0.0296
Trypanosoma cruzi cruzipain precursor, putative 0.0068 0.0577 0.0589
Mycobacterium ulcerans phenolpthiocerol synthesis type-I polyketide synthase PpsC 0.0144 0.1351 0.1345
Onchocerca volvulus Rap guanine nucleotide exchange factor 1 homolog 0.0016 0.005 0.0053
Leishmania major protein kinase, putative 0.0013 0.002 0.0014
Trypanosoma brucei beta-ketoacyl-ACP synthase 0.0034 0.0236 0.023
Schistosoma mansoni acyl carrier protein 0.0014 0.003 0.003
Echinococcus granulosus calcium dependent protein kinase 0.0016 0.0054 0.0066
Schistosoma mansoni microtubule-associated protein tau 0.0674 0.6708 0.6708
Echinococcus granulosus somatostatin receptor 0.0019 0.0087 0.0106
Schistosoma mansoni hypothetical protein 0.0161 0.1516 0.1516
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0019 0.0087 0.0087
Trichomonas vaginalis Clan CA, family C1, papain-like cysteine peptidase 0.0018 0.0071 0.0071
Entamoeba histolytica Ras guanine nucleotide exchange factor, putative 0.0016 0.005 0.0081
Schistosoma mansoni biogenic amine (dopamine) receptor 0.0019 0.0087 0.0087
Trypanosoma brucei glucose transporter, putative 0.0017 0.0067 0.0052
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0019 0.0087 0.0087
Plasmodium vivax hypothetical protein, conserved 0.0019 0.0088 0.038
Echinococcus granulosus G protein coupled receptor 139 0.0019 0.0087 0.0106
Mycobacterium leprae PROBABLE THIOESTERASE TESA 0.0113 0.1036 0.5311
Loa Loa (eye worm) serotonin transporter b 0.0693 0.6901 0.6899
Leishmania major hypothetical protein, conserved 0.0041 0.0302 0.031
Entamoeba histolytica hypothetical protein 0.0013 0.0018 0.0029
Echinococcus multilocularis growth hormone secretagogue receptor type 1 0.0019 0.0087 0.0098
Loa Loa (eye worm) hypothetical protein 0.0229 0.221 0.2205
Loa Loa (eye worm) hypothetical protein 0.0041 0.0302 0.0296
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0019 0.0087 0.0087
Brugia malayi Papain family cysteine protease containing protein 0.0018 0.0071 0.0065
Brugia malayi isocitrate dehydrogenase 0.0094 0.0845 0.0839
Brugia malayi hypothetical protein 0.0185 0.176 0.1755
Trichomonas vaginalis glucosylceramidase, putative 0.009 0.0798 0.0798
Echinococcus multilocularis Zinc finger, RanBP2 type 0.0057 0.0469 0.0529
Trypanosoma brucei THT1 - hexose transporter, putative 0.0017 0.0067 0.0052
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0068 0.0577 0.0589
Trypanosoma brucei bifunctional aminoacyl-tRNA synthetase, putative 0.002 0.0089 0.0075
Brugia malayi bifunctional aminoacyl-tRNA synthetase 0.0017 0.0061 0.0055
Trypanosoma cruzi Zn-finger in Ran binding protein and others/FYVE zinc finger, putative 0.0057 0.0469 0.0475
Brugia malayi Zn-finger in Ran binding protein and others containing protein 0.0057 0.0469 0.0463
Mycobacterium ulcerans acyl carrier protein 0.0014 0.003 0.0023
Entamoeba histolytica tartrate dehydrogenase, putative 0.0011 0.0007 0.0011
Loa Loa (eye worm) beta-LACTamase domain containing family member 0.0041 0.0302 0.0296
Brugia malayi Sodium:neurotransmitter symporter family protein 0.0693 0.6901 0.6899
Loa Loa (eye worm) G-protein coupled receptor 0.0019 0.0087 0.0081
Brugia malayi photoreceptor-specific nuclear receptor 0.0153 0.1439 0.1433
Mycobacterium ulcerans thioesterase 0.0113 0.1036 0.103
Echinococcus multilocularis neuropeptides capa receptor 0.0019 0.0087 0.0098
Leishmania major protein kinase, putative 0.0013 0.002 0.0014
Echinococcus multilocularis NADP dependent isocitrate dehydrogenase 0.0094 0.0845 0.0953
Leishmania major hypothetical protein, conserved 0.0057 0.0469 0.0486
Entamoeba histolytica cysteine proteinase, putative 0.0012 0.0012 0.0019
Trypanosoma cruzi hexose transporter, putative 0.0017 0.0067 0.0052
Loa Loa (eye worm) hypothetical protein 0.0019 0.0087 0.0081
Schistosoma mansoni hypothetical protein 0.0169 0.1599 0.1599
Echinococcus granulosus General substrate transporter 0.0048 0.0379 0.0462
Echinococcus multilocularis sex peptide receptor 0.0019 0.0087 0.0098
Trypanosoma cruzi prolyl-tRNA synthetase, putative 0.002 0.0089 0.0075
Loa Loa (eye worm) RasGEF domain-containing protein 0.0016 0.005 0.0043
Trypanosoma cruzi major cysteine proteinase, putative 0.0053 0.0431 0.0434
Brugia malayi hypothetical protein 0.0019 0.0087 0.0081
Mycobacterium ulcerans hypothetical protein 0.0041 0.0302 0.0295
Brugia malayi Beta-ketoacyl synthase, N-terminal domain containing protein 0.0136 0.1265 0.126
Schistosoma mansoni serine/threonine protein kinase 0.0013 0.002 0.002
Onchocerca volvulus 0.0019 0.0087 0.0099
Echinococcus granulosus Basic leucine zipper bZIP transcription 0.008 0.07 0.0854
Loa Loa (eye worm) hypothetical protein 0.0057 0.0469 0.0463
Toxoplasma gondii ABC1 family protein 0.0041 0.0302 0.1715
Loa Loa (eye worm) hypothetical protein 0.0118 0.1081 0.1075
Trichomonas vaginalis CAMK family protein kinase 0.0019 0.0085 0.0085
Echinococcus multilocularis sodium:chloride dependent neurotransmitter 0.0118 0.1081 0.122
Onchocerca volvulus Cathepsin L homolog 0.0018 0.0071 0.0079
Trypanosoma cruzi WLM domain containing protein, putative 0.0057 0.0469 0.0475
Trichomonas vaginalis D-aminoacylase, putative 0.0041 0.0302 0.0302
Mycobacterium tuberculosis Hypothetical protein 0.0041 0.0305 0.0754
Echinococcus granulosus pyroglutamylated rfamide peptide receptor 0.0019 0.0087 0.0106
Echinococcus granulosus zinc finger protein Ran binding 0.0057 0.0469 0.0573
Schistosoma mansoni sodium-dependent neurotransmitter transporter 0.0118 0.1081 0.1081
Schistosoma mansoni hypothetical protein 0.0365 0.3582 0.3582
Chlamydia trachomatis 3-oxoacyl-ACP synthase 0.0034 0.0236 0.1456
Echinococcus multilocularis lysyl tRNA synthetase 0.0013 0.0018 0.002
Mycobacterium tuberculosis Probable conserved lipoprotein LpqF 0.0193 0.1844 0.4648
Entamoeba histolytica Ras guanine nucleotide exchange factor, putative 0.0016 0.005 0.0081
Loa Loa (eye worm) hypothetical protein 0.0022 0.0114 0.0107
Echinococcus multilocularis hepatocyte nuclear factor 4 alpha 0.0011 0.0006 0.0007
Mycobacterium ulcerans phenolpthiocerol synthesis type-I polyketide synthase PpsE 0.009 0.08 0.0793
Entamoeba histolytica prolyl-tRNA synthetase, putative 0.0017 0.0061 0.01
Loa Loa (eye worm) Papain cysteine protease/cathepsin propeptide inhibitor-containing protein 0.0018 0.0071 0.0065
Trichomonas vaginalis CAMK family protein kinase 0.0619 0.6156 0.6156
Brugia malayi oxidoreductase, short chain dehydrogenase/reductase family protein 0.0021 0.0107 0.01
Mycobacterium tuberculosis Probable thioesterase TesA 0.0113 0.1036 0.2604
Loa Loa (eye worm) G-protein coupled receptor 0.0019 0.0087 0.0081
Loa Loa (eye worm) hypothetical protein 0.0169 0.1599 0.1594
Loa Loa (eye worm) hypothetical protein 0.0185 0.176 0.1755
Mycobacterium tuberculosis Probable polyketide synthase Pks9 0.0077 0.0672 0.1684
Loa Loa (eye worm) melatonin receptor type 1A 0.0019 0.0087 0.0081
Echinococcus granulosus neuropeptide s receptor 0.0019 0.0087 0.0106
Echinococcus granulosus rhodopsin orphan GPCR 0.0019 0.0087 0.0106
Echinococcus multilocularis rhodopsin orphan GPCR 0.0019 0.0087 0.0098
Brugia malayi Serotonin receptor 0.0019 0.0087 0.0081
Loa Loa (eye worm) hypothetical protein 0.0019 0.0087 0.0081
Schistosoma mansoni ras GTP exchange factor son of sevenless 0.0016 0.005 0.005
Schistosoma mansoni hypothetical protein 0.0169 0.1599 0.1599
Trichomonas vaginalis glucosylceramidase, putative 0.009 0.0798 0.0798
Trypanosoma brucei hypothetical protein, conserved 0.0041 0.0302 0.0299
Loa Loa (eye worm) hypothetical protein 0.0016 0.005 0.0043
Mycobacterium leprae Probable polyketide synthase Pks1 0.0144 0.1351 0.6934
Brugia malayi RNA recognition motif domain containing protein 0.0129 0.1198 0.1193
Brugia malayi ORL1-like opioid receptor 0.0019 0.0087 0.0081
Brugia malayi brahma associated protein 60 kDa 0.0161 0.1516 0.1511
Mycobacterium ulcerans acyl-CoA synthetase 0.0021 0.0107 0.01
Onchocerca volvulus 0.0018 0.0071 0.0079
Echinococcus multilocularis uncharacterized sodium dependent transporter 0.0118 0.1081 0.122
Schistosoma mansoni biogenic amine (5HT) receptor 0.0438 0.4324 0.4324
Onchocerca volvulus 0.0018 0.0071 0.0079
Schistosoma mansoni chromobox protein 0.0059 0.0491 0.0491
Schistosoma mansoni neuropeptide F-like receptor 0.0019 0.0087 0.0087
Loa Loa (eye worm) latrophilin receptor protein 2 0.0169 0.1599 0.1594
Mycobacterium tuberculosis Probable polyketide synthase Pks1 0.0098 0.0878 0.2205
Loa Loa (eye worm) phosphopantetheine attachment site family protein 0.0014 0.003 0.0023
Mycobacterium tuberculosis Conserved protein 0.0041 0.0305 0.0754
Brugia malayi Cathepsin L-like precursor 0.0012 0.0012 0.0005
Loa Loa (eye worm) hypothetical protein 0.0012 0.0012 0.0005
Leishmania major cathepsin L-like protease 0.0018 0.0071 0.0068
Loa Loa (eye worm) G protein signaling regulator EGL-10 0.0022 0.0114 0.0107
Trypanosoma brucei glucose transporter, putative 0.0017 0.0067 0.0052
Echinococcus granulosus GPCR family 2 0.0169 0.1599 0.1952
Entamoeba histolytica cysteine protease, putative 0.0018 0.0071 0.0116
Mycobacterium tuberculosis Class a beta-lactamase BlaC 0.0402 0.3959 1
Schistosoma mansoni sodium/chloride dependent neurotransmitter transporter 0.0118 0.1081 0.1081
Trypanosoma brucei hypothetical protein, conserved 0.0057 0.0469 0.0475
Echinococcus multilocularis histone lysine N methyltransferase SETMAR 0.0052 0.042 0.0473
Loa Loa (eye worm) vesicular acetylcholine transporter unc-17 0.0821 0.8191 0.819
Loa Loa (eye worm) hypothetical protein 0.0026 0.0155 0.0148
Toxoplasma gondii type I fatty acid synthase, putative 0.0145 0.1361 0.7734
Loa Loa (eye worm) RasGEF domain-containing protein 0.0016 0.005 0.0043
Loa Loa (eye worm) hypothetical protein 0.0026 0.0153 0.0147
Mycobacterium tuberculosis Possible penicillin-binding protein 0.0259 0.2515 0.6347
Echinococcus multilocularis neuropeptide receptor 0.0019 0.0087 0.0098
Schistosoma mansoni serine/threonine protein kinase 0.0019 0.0085 0.0085
Leishmania major cathepsin L-like protease 0.0068 0.0577 0.0599
Echinococcus multilocularis cathepsin l cysteine peptidase 0.0018 0.0071 0.008
Echinococcus granulosus rhodopsin orphan GPCR 0.0019 0.0087 0.0106
Mycobacterium tuberculosis Probable polyketide beta-ketoacyl synthase Pks4 0.0021 0.0102 0.024
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0018 0.0071 0.0071
Brugia malayi RasGEF domain containing protein 0.0016 0.005 0.0043
Loa Loa (eye worm) hypothetical protein 0.0022 0.0114 0.0107
Schistosoma mansoni amine GPCR 0.0019 0.0087 0.0087
Schistosoma mansoni sodium/chloride dependent neurotransmitter transporter 0.0118 0.1081 0.1081
Loa Loa (eye worm) hypothetical protein 0.0019 0.0087 0.0081
Echinococcus granulosus glutamyl tRNA synthetase cytoplasmic 0.0017 0.0061 0.0075
Echinococcus granulosus microtubule associated protein 2 0.0674 0.6708 0.819
Trypanosoma cruzi hypothetical protein 0.0016 0.005 0.0034
Mycobacterium tuberculosis Conserved protein 0.0041 0.0302 0.0746
Wolbachia endosymbiont of Brugia malayi acyl carrier protein 0.0014 0.003 0.1002
Trichomonas vaginalis conserved hypothetical protein 0.0056 0.0458 0.0458
Loa Loa (eye worm) fatty acid synthase 0.0134 0.1247 0.1241
Echinococcus multilocularis 3 oxoacyl (acyl carrier protein) synthase 0.0034 0.0236 0.0266
Echinococcus multilocularis tm gpcr rhodopsin gpcr rhodopsin superfamily 0.0019 0.0087 0.0098
Onchocerca volvulus 0.0019 0.0087 0.0099
Schistosoma mansoni family S12 unassigned peptidase (S12 family) 0.0041 0.0302 0.0302
Echinococcus multilocularis thyrotropin releasing hormone receptor 0.0019 0.0087 0.0098
Loa Loa (eye worm) hypothetical protein 0.0019 0.0087 0.0081
Trypanosoma brucei Zn-finger in Ran binding protein and others/FYVE zinc finger, putative 0.0057 0.0469 0.0475
Echinococcus granulosus tm gpcr rhodopsin 0.0019 0.0087 0.0106
Echinococcus multilocularis histone lysine methyltransferase setb histone lysine methyltransferase eggless 0.0052 0.042 0.0473
Leishmania major 4-coumarate:coa ligase-like protein 0.0026 0.0153 0.0154
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0018 0.0071 0.0071
Schistosoma mansoni amine GPCR 0.0019 0.0087 0.0087
Echinococcus granulosus rhodopsin orphan GPCR 0.0019 0.0087 0.0106
Plasmodium falciparum SWIB/MDM2 domain-containing protein 0.0161 0.1516 0.6538
Echinococcus granulosus isocitrate dehydrogenase NAD subunit 0.0011 0.0007 0.0008
Schistosoma mansoni ras GTP exchange factor son of sevenless 0.0016 0.005 0.005
Mycobacterium tuberculosis Probable fatty-acid-CoA ligase FadD3 (fatty-acid-CoA synthetase) (fatty-acid-CoA synthase) 0.0018 0.0076 0.0176
Trypanosoma brucei isocitrate dehydrogenase, putative 0.0094 0.0845 0.087
Echinococcus multilocularis NADH dehydrogenase 0.0014 0.003 0.0034
Brugia malayi Dopamine receptor 0.0019 0.0087 0.0081
Trichomonas vaginalis glucosylceramidase, putative 0.009 0.0798 0.0798
Trichomonas vaginalis glucosylceramidase, putative 0.009 0.0798 0.0798
Loa Loa (eye worm) hypothetical protein 0.0019 0.0087 0.0081
Loa Loa (eye worm) unidentified vitellogenin-linked transcript protein 6 0.0019 0.0087 0.0081
Loa Loa (eye worm) hypothetical protein 0.0118 0.1081 0.1075
Echinococcus granulosus 7TM GPCR rhodopsin 0.0019 0.0087 0.0106
Brugia malayi follicle stimulating hormone receptor 0.0019 0.0087 0.0081
Loa Loa (eye worm) hypothetical protein 0.0022 0.0114 0.0107
Echinococcus granulosus segment polarity protein dishevelled 0.0022 0.0114 0.0139
Plasmodium falciparum cysteine proteinase falcipain 2a 0.0018 0.0071 0.0307
Trichomonas vaginalis conserved hypothetical protein 0.0024 0.0129 0.0129
Toxoplasma gondii type I fatty acid synthase, putative 0.0097 0.0869 0.4939
Mycobacterium ulcerans peptide synthetase Nrp (peptide synthase) 0.0021 0.0107 0.01
Mycobacterium ulcerans 3-oxoacyl-(acyl carrier protein) synthase II 0.0034 0.0236 0.0229
Schistosoma mansoni ras GTP exchange factor 0.0016 0.005 0.005
Loa Loa (eye worm) hypothetical protein 0.0118 0.1081 0.1075
Plasmodium vivax acyl carrier protein, putative 0.0014 0.003 0.0129
Brugia malayi hypothetical protein 0.008 0.07 0.0694
Trypanosoma cruzi prolyl-tRNA synthetase, putative 0.002 0.0089 0.0075
Treponema pallidum sodium- and chloride- dependent transporter 0.0693 0.6901 1
Plasmodium falciparum protein kinase 7 0.016 0.1514 0.6529
Echinococcus granulosus Ataxin 2 N terminaldomain containing protein 0.0083 0.0729 0.089
Onchocerca volvulus 0.0012 0.0012 0.0006
Echinococcus granulosus rhodopsin orphan GPCR 0.0019 0.0087 0.0106
Onchocerca volvulus 0.0019 0.0087 0.0099
Echinococcus granulosus biogenic amine 5HT receptor 0.0438 0.4324 0.5279
Entamoeba histolytica Ras guanine nucleotide exchange factor, putative 0.0016 0.005 0.0081
Leishmania major C-8 sterol isomerase-like protein 0.0953 0.9528 1
Brugia malayi Latrophilin receptor protein 2 0.0169 0.1599 0.1594
Entamoeba histolytica Ras guanine nucleotide exchange factor, putative 0.0016 0.005 0.0081
Echinococcus granulosus ecdysone induced protein 78C 0.0011 0.0006 0.0008
Schistosoma mansoni biogenic amine (5HT) receptor 0.0019 0.0087 0.0087
Trichomonas vaginalis chromobox protein, putative 0.0036 0.0253 0.0253
Trichomonas vaginalis CAMK family protein kinase 0.0619 0.6156 0.6156
Onchocerca volvulus Glucosylceramidase homolog 0.009 0.0798 0.0967
Echinococcus multilocularis alpha 1A adrenergic receptor 0.0019 0.0087 0.0098
Echinococcus multilocularis solute carrier family 2 facilitated glucose 0.0056 0.0458 0.0517
Leishmania major hypothetical protein, conserved 0.0185 0.176 0.1841
Toxoplasma gondii Zn-finger in Ran binding protein and others domain-containing protein 0.0057 0.0469 0.2666
Mycobacterium ulcerans beta-lactamase 0.0041 0.0302 0.0295
Loa Loa (eye worm) hypothetical protein 0.0019 0.0087 0.0081
Schistosoma mansoni biogenic amine receptor 0.0019 0.0087 0.0087
Echinococcus granulosus retinoic acid receptor rxr beta a 0.0011 0.0006 0.0008
Leishmania major hypothetical protein, conserved 0.0041 0.0305 0.0313
Plasmodium falciparum mitogen-activated protein kinase 2 0.0093 0.0828 0.3571
Echinococcus multilocularis FTZ F1 nuclear receptor protein 0.0011 0.0006 0.0007
Toxoplasma gondii histone lysine methyltransferase SET/SUV39 0.0052 0.042 0.2384
Echinococcus multilocularis ecdysone induced protein 78C 0.0011 0.0006 0.0007
Loa Loa (eye worm) hypothetical protein 0.0019 0.0087 0.0081
Plasmodium falciparum calcium-dependent protein kinase 5 0.0019 0.0085 0.0368
Echinococcus granulosus cathepsin l1 0.0012 0.0012 0.0014
Schistosoma mansoni alpha-1 adrenergic receptor 0.0019 0.0087 0.0087
Mycobacterium tuberculosis Probable membrane bound polyketide synthase Pks6 0.0203 0.1945 0.4903
Mycobacterium tuberculosis Polyketide synthetase MbtD (polyketide synthase) 0.0042 0.0314 0.0776
Echinococcus granulosus thyrotropin releasing hormone receptor 0.0019 0.0087 0.0106
Brugia malayi Isocitrate dehydrogenase 0.0094 0.0845 0.0839
Echinococcus multilocularis calcium:calmodulin dependent protein kinase type 0.0019 0.0085 0.0096
Loa Loa (eye worm) hypothetical protein 0.0019 0.0087 0.0081
Schistosoma mansoni histamine-responsive GPCR (AAF21638) 0.0019 0.0087 0.0087
Schistosoma mansoni dep domain containing protein 0.0022 0.0114 0.0114
Trichomonas vaginalis glucosylceramidase, putative 0.0094 0.0847 0.0847
Plasmodium falciparum ataxin-2 like protein, putative 0.0185 0.176 0.7589
Echinococcus multilocularis serotonin receptor 0.0438 0.4324 0.4879
Mycobacterium tuberculosis Probable polyketide synthase Pks7 0.0144 0.1351 0.34
Trypanosoma cruzi guanine nucleotide releasing protein, putative 0.0016 0.005 0.0034
Toxoplasma gondii calcium-dependent protein kinase CDPK2B 0.0019 0.0085 0.0484
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0018 0.0071 0.0071
Toxoplasma gondii Sodium:neurotransmitter symporter family protein 0.0118 0.1081 0.6142
Leishmania major glucose transporter, lmgt2 0.0017 0.0067 0.0063
Brugia malayi Tachykinin-like peptides receptor 99D 0.0019 0.0087 0.0081
Leishmania major cathepsin L-like protease 0.0018 0.0071 0.0068
Brugia malayi SWIB/MDM2 domain containing protein 0.0161 0.1516 0.1511
Echinococcus granulosus fmrfamide receptor 0.0019 0.0087 0.0106
Brugia malayi calcium-independent alpha-latrotoxin receptor 2, putative 0.0169 0.1599 0.1594
Trichomonas vaginalis conserved hypothetical protein 0.0024 0.0129 0.0129
Wolbachia endosymbiont of Brugia malayi 3-oxoacyl-ACP synthase 0.0034 0.0236 1
Plasmodium falciparum conserved Plasmodium protein, unknown function 0.0019 0.0088 0.038
Brugia malayi YY1-associated factor 2 0.0057 0.0469 0.0463
Onchocerca volvulus Acyl carrier protein, mitochondrial homolog 0.0014 0.003 0.0029
Echinococcus granulosus hypothetical protein 0.0019 0.0087 0.0106
Schistosoma mansoni protein kinase 0.0019 0.0085 0.0085
Loa Loa (eye worm) DIX domain-containing protein 0.0022 0.0114 0.0107
Brugia malayi Cathepsin L-like cysteine proteinase 0.0012 0.0012 0.0005
Brugia malayi oxidoreductase, zinc-binding dehydrogenase family protein 0.0257 0.2496 0.2491
Schistosoma mansoni norepinephrine/norepinephrine transporter 0.0693 0.6901 0.6901
Echinococcus granulosus growth hormone secretagogue receptor type 1 0.0019 0.0087 0.0106
Trichomonas vaginalis glucosylceramidase, putative 0.0137 0.1273 0.1273
Echinococcus multilocularis solute carrier family 2, facilitated glucose 0.0056 0.0458 0.0517
Schistosoma mansoni nuclear hormone receptor nor-1/nor-2 0.0011 0.0006 0.0006
Mycobacterium tuberculosis Polyketide synthase Pks12 0.0144 0.1351 0.34
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0068 0.0577 0.0589
Plasmodium falciparum hexose transporter 0.0056 0.0458 0.1976
Loa Loa (eye worm) AMP-binding enzyme family protein 0.0135 0.1252 0.1246
Onchocerca volvulus 0.0118 0.1081 0.1313
Mycobacterium ulcerans hypothetical protein 0.0014 0.003 0.0023
Schistosoma mansoni muscarinic acetylcholine (GAR) receptor 0.0019 0.0087 0.0087
Onchocerca volvulus 0.0019 0.0087 0.0099
Mycobacterium leprae PHENOLPTHIOCEROL SYNTHESIS TYPE-I POLYKETIDE SYNTHASE PPSB 0.0109 0.0997 0.5108
Echinococcus multilocularis cathepsin L cysteine protease 0.0018 0.0071 0.008
Loa Loa (eye worm) hypothetical protein 0.0012 0.0012 0.0005
Trypanosoma cruzi mitochondrial RNA binding complex 1 subunit, putative 0.0057 0.0469 0.0475
Schistosoma mansoni chromobox protein 0.0059 0.0491 0.0491
Onchocerca volvulus 0.0019 0.0087 0.0099
Leishmania major hypothetical protein, conserved 0.0057 0.0469 0.0486
Schistosoma mansoni hypothetical protein 0.0057 0.0469 0.0469
Echinococcus multilocularis NADP dependent isocitrate dehydrogenase 0.0094 0.0845 0.0953
Echinococcus granulosus rap guanine nucleotide exchange factor 1 0.0016 0.005 0.0061
Echinococcus granulosus sodium:chloride dependent neurotransmitter 0.0118 0.1081 0.132
Echinococcus granulosus alpha 1A adrenergic receptor 0.0019 0.0087 0.0106
Mycobacterium leprae PROBABLE FATTY-ACID-CoA LIGASE FADD7 (FATTY-ACID-CoA SYNTHETASE) (FATTY-ACID-CoA SYNTHASE) 0.0026 0.0153 0.0756
Trichomonas vaginalis Clan CA, family C1, papain-like cysteine peptidase 0.0018 0.0071 0.0071
Trichomonas vaginalis guanine nucleotide exchange factor, putative 0.0016 0.005 0.005
Loa Loa (eye worm) hypothetical protein 0.0057 0.0469 0.0463
Mycobacterium ulcerans polyketide synthase Pks9 0.009 0.08 0.0793
Echinococcus granulosus beta LACTamase domain containing family member 0.0041 0.0302 0.0369
Echinococcus multilocularis g protein coupled receptor 0.0019 0.0087 0.0098
Mycobacterium ulcerans phenolpthiocerol synthesis type-I polyketide synthase PpsB 0.0109 0.0997 0.099
Mycobacterium tuberculosis Probable fatty-acid-CoA ligase FadD2 (fatty-acid-CoA synthetase) (fatty-acid-CoA synthase) 0.0026 0.0153 0.0371
Echinococcus multilocularis SWI:SNF matrix associated 0.0161 0.1516 0.1711
Trichomonas vaginalis glucosylceramidase, putative 0.0137 0.1273 0.1273
Mycobacterium tuberculosis Probable polyketide beta-ketoacyl synthase Pks3 0.0021 0.0102 0.024
Loa Loa (eye worm) hypothetical protein 0.0019 0.0087 0.0081
Mycobacterium leprae Probable prolyl tRNA synthetase ProS 0.0017 0.0061 0.0281
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0068 0.0577 0.0589
Brugia malayi AMP-binding enzyme family protein 0.0026 0.0153 0.0147
Loa Loa (eye worm) hypothetical protein 0.0041 0.0302 0.0296
Echinococcus multilocularis segment polarity protein dishevelled 0.0022 0.0114 0.0128
Brugia malayi Sugar transporter family protein 0.0056 0.0458 0.0452
Loa Loa (eye worm) hypothetical protein 0.0019 0.0087 0.0081
Echinococcus multilocularis cadherin EGF LAG seven pass G type receptor 0.0169 0.1599 0.1805
Schistosoma mansoni Tr4/Tr2 (homologue) 0.0011 0.0006 0.0006
Leishmania major acyl carrier protein, putative 0.0014 0.003 0.0024
Loa Loa (eye worm) hypothetical protein 0.0019 0.0087 0.0081
Plasmodium vivax ataxin-2 like protein, putative 0.0185 0.176 0.7589
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0068 0.0577 0.0589
Loa Loa (eye worm) hypothetical protein 0.0057 0.0469 0.0463
Echinococcus granulosus cGMP dependent protein kinase 0.0013 0.002 0.0024
Echinococcus granulosus nuclear receptor 2DBD gamma 0.0011 0.0006 0.0008
Schistosoma mansoni peptide (FMRFamide/somatostatin)-like receptor 0.0019 0.0087 0.0087
Echinococcus multilocularis cGMP dependent protein kinase 1 0.0013 0.002 0.0022
Plasmodium falciparum amino acid transporter, putative 0.0118 0.1081 0.4661
Schistosoma mansoni ancient conserved domain protein 2 (cyclin m2) 0.0019 0.0087 0.0087
Echinococcus multilocularis g protein linked acetylcholine receptor gar 2a 0.0019 0.0087 0.0098
Brugia malayi hypothetical protein 0.0019 0.0087 0.0081
Brugia malayi lysyl-tRNA synthetase 0.0013 0.0018 0.0011
Echinococcus granulosus chromobox protein 1 0.0059 0.0491 0.06
Echinococcus granulosus tm gpcr rhodopsin 0.0019 0.0087 0.0106
Onchocerca volvulus Rap guanine nucleotide exchange factor 1 homolog 0.0447 0.4415 0.5387
Brugia malayi Cathepsin L-like precursor 0.0018 0.0071 0.0065
Leishmania major cathepsin L-like protease 0.0068 0.0577 0.0599
Brugia malayi hypothetical protein 0.0119 0.1098 0.1092
Chlamydia trachomatis SWIB complex protein 0.0161 0.1516 1
Loa Loa (eye worm) hypothetical protein 0.0019 0.0087 0.0081
Schistosoma mansoni 3-oxoacyl-[ACP] synthase 0.0034 0.0236 0.0236
Echinococcus multilocularis cysteine protease 0.0018 0.0071 0.008
Loa Loa (eye worm) papain family cysteine protease containing protein 0.0018 0.0071 0.0065
Echinococcus granulosus solute carrier family 2 facilitated glucose 0.0056 0.0458 0.056
Schistosoma mansoni histone-lysine n-methyltransferase suv9 0.0062 0.0518 0.0518
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0068 0.0577 0.0589
Schistosoma mansoni ras GTP exchange factor son of sevenless 0.0016 0.005 0.005
Brugia malayi Zn-finger in Ran binding protein and others containing protein 0.0057 0.0469 0.0463
Trichomonas vaginalis Clan CA, family C1, papain-like cysteine peptidase 0.0018 0.0071 0.0071
Leishmania major prolyl-tRNA synthetase, putative,bifunctional aminoacyl-tRNA synthetase, putative 0.002 0.0089 0.0087
Echinococcus granulosus sodium dependent neurotransmitter transporter 0.0118 0.1081 0.132
Onchocerca volvulus 0.0018 0.0071 0.0079
Plasmodium vivax 3-oxoacyl-[acyl-carrier-protein] synthase i/ii, putative 0.0034 0.0236 0.1017
Loa Loa (eye worm) hypothetical protein 0.0014 0.0029 0.0023
Echinococcus multilocularis tm gpcr rhodopsin gpcr rhodopsin superfamily 0.0019 0.0087 0.0098
Loa Loa (eye worm) hypothetical protein 0.0019 0.0087 0.0081
Loa Loa (eye worm) TAR-binding protein 0.0129 0.1198 0.1193
Trichomonas vaginalis glucose transporter, putative 0.0017 0.0067 0.0067
Brugia malayi neuropeptide F receptor 0.0019 0.0087 0.0081
Mycobacterium ulcerans glutaminase 0.0999 1 1
Brugia malayi Unidentified vitellogenin-linked transcript protein 6, putative 0.0019 0.0087 0.0081
Onchocerca volvulus 0.0019 0.0087 0.0099
Echinococcus granulosus Pleckstrin G protein interacting region 0.0022 0.0114 0.0139
Schistosoma mansoni hypothetical protein 0.0161 0.1516 0.1516
Echinococcus multilocularis pyroglutamylated rfamide peptide receptor 0.0019 0.0087 0.0098
Trichomonas vaginalis glucosylceramidase, putative 0.0137 0.1273 0.1273
Schistosoma mansoni photoreceptor-specific nuclear receptor related 0.0011 0.0006 0.0006
Mycobacterium ulcerans polyketide synthase 0.0144 0.1351 0.1345
Echinococcus multilocularis son of sevenless 1 0.0016 0.005 0.0056
Brugia malayi Corticotropin releasing factor receptor 2 precursor, putative 0.0534 0.529 0.5287
Trypanosoma cruzi hypothetical protein 0.0016 0.005 0.0034
Brugia malayi hypothetical protein 0.0022 0.0114 0.0107
Echinococcus multilocularis G-protein coupled receptor, putative 0.0019 0.0087 0.0098
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0018 0.0071 0.0071
Echinococcus multilocularis rhodopsin orphan GPCR 0.0019 0.0087 0.0098
Echinococcus granulosus peptide allatostatin:somatostatin 0.0019 0.0087 0.0106
Echinococcus granulosus rhodopsin orphan GPCR 0.0019 0.0087 0.0106
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0068 0.0577 0.0589
Entamoeba histolytica cysteine proteinase, putative 0.0018 0.0071 0.0116
Brugia malayi Domain found in Dishevelled, Egl-10, and Pleckstrin family protein 0.0022 0.0114 0.0107
Trichomonas vaginalis CAMK family protein kinase 0.0307 0.2998 0.2998
Echinococcus granulosus g protein linked acetylcholine receptor gar 2a 0.0019 0.0087 0.0106
Brugia malayi O-Glycosyl hydrolase family 30 protein 0.0137 0.1273 0.1267
Loa Loa (eye worm) hypothetical protein 0.0057 0.0469 0.0463
Loa Loa (eye worm) hypothetical protein 0.0019 0.0087 0.0081
Schistosoma mansoni histone-lysine n-methyltransferase setb1 0.0052 0.042 0.042
Echinococcus granulosus orexin receptor type 2 0.0019 0.0087 0.0106
Entamoeba histolytica cysteine proteinase, putative 0.0018 0.0071 0.0116
Mycobacterium leprae Possible lysyl-tRNA synthetase 2 LysX 0.0013 0.0018 0.0056
Brugia malayi SET domain containing protein 0.0012 0.0009 0.0002
Loa Loa (eye worm) G-protein-linked acetylcholine receptor protein 2 0.0019 0.0087 0.0081
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0018 0.0071 0.0071
Plasmodium falciparum acyl-CoA synthetase 0.0019 0.0087 0.0375
Loa Loa (eye worm) hypothetical protein 0.0019 0.0087 0.0081
Echinococcus multilocularis SWI:SNF matrix associated 0.0161 0.1516 0.1711
Mycobacterium ulcerans polyketide synthase MbtD 0.0042 0.0314 0.0307
Trichomonas vaginalis prolyl-tRNA synthetase, putative 0.0017 0.0061 0.0061
Echinococcus granulosus neuropeptides capa receptor 0.0019 0.0087 0.0106
Brugia malayi G-protein coupled receptor 0.0019 0.0087 0.0081
Loa Loa (eye worm) gonadotropin-releasing hormone receptor 2 0.0019 0.0087 0.0081
Loa Loa (eye worm) hypothetical protein 0.0019 0.0087 0.0081
Mycobacterium tuberculosis Probable lipase LipE 0.0041 0.0302 0.0746
Loa Loa (eye worm) hypothetical protein 0.0693 0.6901 0.6899
Trichomonas vaginalis sugar transporter, putative 0.0017 0.0067 0.0067
Loa Loa (eye worm) hypothetical protein 0.0019 0.0087 0.0081
Schistosoma mansoni norepinephrine/norepinephrine transporter 0.0118 0.1081 0.1081
Echinococcus multilocularis serotonin receptor 0.0438 0.4324 0.4879
Mycobacterium tuberculosis Probable polyketide synthase Pks8 0.0111 0.1015 0.255
Loa Loa (eye worm) hypothetical protein 0.0019 0.0087 0.0081
Trichomonas vaginalis glutaminase, putative 0.0999 1 1
Schistosoma mansoni histone-lysine n-methyltransferase setb1 0.0052 0.042 0.042
Trichomonas vaginalis CAMK family protein kinase 0.0619 0.6156 0.6156
Loa Loa (eye worm) hypothetical protein 0.0076 0.0661 0.0655
Echinococcus granulosus g protein coupled receptor 0.0019 0.0087 0.0106
Loa Loa (eye worm) hypothetical protein 0.0019 0.0087 0.0081
Schistosoma mansoni fusion 0.0057 0.0469 0.0469
Schistosoma mansoni opsin-like receptor 0.0019 0.0087 0.0087
Chlamydia trachomatis acylglycerophosphoethanolamine acyltransferase 0.0019 0.0087 0.0463
Echinococcus multilocularis calcium:calmodulin dependent protein kinase type 0.0019 0.0085 0.0096
Plasmodium falciparum protein kinase 6 0.024 0.2319 1
Brugia malayi hypothetical protein 0.0022 0.0114 0.0107
Echinococcus multilocularis solute carrier family 2 facilitated glucose 0.0056 0.0458 0.0517
Trichomonas vaginalis glucosylceramidase, putative 0.009 0.0798 0.0798
Echinococcus multilocularis NADP dependent isocitrate dehydrogenase 0.0094 0.0845 0.0953
Giardia lamblia Lysyl-tRNA synthetase 0.0013 0.0018 0.0029
Chlamydia trachomatis Ssodium-dependent amino acid transporter 0.0118 0.1081 0.7096
Brugia malayi chromobox protein homolog 3 0.0033 0.0227 0.0221
Echinococcus multilocularis neuropeptides capa receptor 0.0019 0.0087 0.0098
Onchocerca volvulus Neuropeptide F receptor homolog 0.0019 0.0087 0.0099
Brugia malayi neuropeptide F receptor 0.0019 0.0087 0.0081
Plasmodium falciparum zinc finger Ran-binding domain-containing protein 2, putative 0.0057 0.0469 0.2023
Trypanosoma cruzi Zn-finger in Ran binding protein and others, putative 0.0057 0.0469 0.0475
Echinococcus multilocularis Ataxin 2, N terminal,domain containing protein 0.0083 0.0729 0.0823
Toxoplasma gondii prolyl-tRNA synthetase (ProRS) 0.002 0.0089 0.0508
Onchocerca volvulus 0.0415 0.4084 0.4982
Trypanosoma brucei PAB1-binding protein , putative 0.0185 0.176 0.1832
Brugia malayi Hypothetical 52.5 kDa protein ZK945.1 in chromosome II, putative 0.0041 0.0302 0.0296
Schistosoma mansoni lysyl-tRNA synthetase 0.0013 0.0018 0.0018
Trichomonas vaginalis Clan CA, family C1, papain-like cysteine peptidase 0.0018 0.0071 0.0071
Mycobacterium ulcerans Type I modular polyketide synthase 0.0136 0.1265 0.1259
Echinococcus multilocularis ras GTP exchange factor 0.0016 0.005 0.0056
Echinococcus granulosus cadherin EGF LAG seven pass G type receptor 0.0169 0.1599 0.1952
Mycobacterium tuberculosis Peptide synthetase MbtF (peptide synthase) 0.0021 0.0107 0.0253
Trichomonas vaginalis glucosylceramidase, putative 0.0137 0.1273 0.1273
Schistosoma mansoni cathepsin F (C01 family) 0.0018 0.0071 0.0071
Loa Loa (eye worm) hypothetical protein 0.0057 0.0469 0.0463
Toxoplasma gondii acyl carrier protein ACP 0.0014 0.003 0.017
Echinococcus granulosus neuropeptide receptor 0.0019 0.0087 0.0106
Trichomonas vaginalis CAMK family protein kinase 0.0619 0.6156 0.6156
Plasmodium falciparum calcium-dependent protein kinase 4 0.0019 0.0085 0.0368
Echinococcus granulosus neuropeptides capa receptor 0.0019 0.0087 0.0106
Schistosoma mansoni NADP-specific isocitrate dehydrogenase 0.0094 0.0845 0.0845
Mycobacterium tuberculosis Probable chain -fatty-acid-CoA ligase FadD13 (fatty-acyl-CoA synthetase) 0.0026 0.0153 0.0371
Echinococcus multilocularis allatostatin A receptor 0.0019 0.0087 0.0098
Schistosoma mansoni kinase 0.0315 0.308 0.308
Loa Loa (eye worm) hypothetical protein 0.0118 0.1081 0.1075
Trypanosoma cruzi hypothetical protein, conserved 0.0041 0.0302 0.0299
Echinococcus granulosus SWI:SNF matrix associated 0.0161 0.1516 0.1851
Echinococcus granulosus dro:myosuppressin receptor 0.0019 0.0087 0.0106
Loa Loa (eye worm) RNA recognition domain-containing protein domain-containing protein 0.0129 0.1198 0.1193
Echinococcus multilocularis rhodopsin orphan GPCR 0.0019 0.0087 0.0098
Plasmodium vivax mitogen-activated protein kinase 2, putative 0.0093 0.0828 0.3571
Loa Loa (eye worm) follicle stimulating hormone receptor 0.0019 0.0087 0.0081
Trypanosoma brucei isocitrate dehydrogenase [NADP], mitochondrial precursor, putative 0.0094 0.0845 0.087
Brugia malayi Sodium:neurotransmitter symporter family protein 0.0118 0.1081 0.1075
Schistosoma mansoni z-protein (S1r protein) 0.0022 0.0114 0.0114
Brugia malayi TAR-binding protein 0.0129 0.1198 0.1193
Trypanosoma brucei glucose transporter, putative 0.0017 0.0067 0.0052
Schistosoma mansoni tar DNA-binding protein 0.0129 0.1198 0.1198
Brugia malayi G-protein-linked acetylcholine receptor protein 2, putative 0.0019 0.0087 0.0081
Echinococcus multilocularis g protein coupled receptor 0.0019 0.0087 0.0098
Echinococcus multilocularis g protein coupled receptor 0.0019 0.0087 0.0098
Toxoplasma gondii ran binding protein 0.0057 0.0469 0.2666
Mycobacterium tuberculosis P-hydroxybenzoyl-AMP ligase FadD22 0.0021 0.0107 0.0253
Brugia malayi Sodium:neurotransmitter symporter family protein 0.0118 0.1081 0.1075
Loa Loa (eye worm) hypothetical protein 0.0019 0.0087 0.0081
Echinococcus multilocularis sodium and chloride dependent glycine 0.0118 0.1081 0.122
Brugia malayi N-terminal motif family protein 0.0016 0.005 0.0043
Echinococcus granulosus tachykinin peptides receptor 99D 0.0019 0.0087 0.0106
Trichomonas vaginalis lysyl-tRNA synthetase, putative 0.0011 0.0002 0.0002
Mycobacterium tuberculosis Fatty-acid-AMP ligase FadD30 (fatty-acid-AMP synthetase) (fatty-acid-AMP synthase) 0.0019 0.0087 0.0203
Onchocerca volvulus 0.0019 0.0087 0.0099
Echinococcus granulosus FTZ F1 nuclear receptor protein 0.0011 0.0006 0.0008
Trichomonas vaginalis Clan CA, family C1, papain-like cysteine peptidase 0.0018 0.0071 0.0071
Onchocerca volvulus 0.0019 0.0087 0.0099
Schistosoma mansoni brg-1 associated factor 0.0161 0.1516 0.1516
Echinococcus multilocularis nuclear receptor 2DBD gamma 0.0011 0.0006 0.0007
Schistosoma mansoni sodium/chloride dependent neurotransmitter transporter 0.0118 0.1081 0.1081
Schistosoma mansoni neuropeptide receptor 0.0019 0.0087 0.0087
Mycobacterium ulcerans phenolpthiocerol synthesis type-I polyketide synthase PpsD 0.0136 0.1265 0.1259
Trichomonas vaginalis Clan CA, family C1, papain-like cysteine peptidase 0.0018 0.0071 0.0071
Brugia malayi hypothetical protein 0.0019 0.0087 0.0081
Loa Loa (eye worm) hypothetical protein 0.0026 0.0153 0.0147
Trypanosoma brucei glucose transporter 1E 0.0017 0.0067 0.0052
Brugia malayi hypothetical protein 0.0019 0.0087 0.0081
Schistosoma mansoni amine GPCR 0.0019 0.0087 0.0087
Echinococcus granulosus solute carrier family 2 facilitated glucose 0.0056 0.0458 0.056
Echinococcus multilocularis Basic leucine zipper (bZIP) transcription 0.008 0.07 0.0789
Plasmodium vivax calcium-dependent protein kinase 4, putative 0.0019 0.0085 0.0368
Schistosoma mansoni hypothetical protein 0.0019 0.0087 0.0087
Trichomonas vaginalis glucosylceramidase, putative 0.0137 0.1273 0.1273
Echinococcus granulosus FTZ F1 alpha 0.0011 0.0006 0.0008
Trypanosoma brucei glucose transporter, putative 0.0017 0.0067 0.0052
Brugia malayi Beta-ketoacyl synthase, N-terminal domain containing protein 0.0034 0.0236 0.023
Echinococcus multilocularis atpase aaa+ type core atpase aaa type core 0.0887 0.8862 1
Leishmania major hypothetical protein, conserved 0.0057 0.0469 0.0486
Echinococcus multilocularis chromobox protein 1 0.0059 0.0491 0.0554
Leishmania major cathepsin L-like protease 0.0018 0.0071 0.0068
Trypanosoma cruzi polo-like protein kinase, putative 0.0619 0.6156 0.6454
Onchocerca volvulus Serine\/threonine kinase homolog 0.0619 0.6156 0.7514
Mycobacterium ulcerans fatty-acid-CoA ligase 0.0026 0.0153 0.0147
Echinococcus granulosus son of sevenless 1 0.0016 0.005 0.0061
Plasmodium falciparum 3-oxoacyl-acyl-carrier protein synthase I/II 0.0034 0.0236 0.1017
Echinococcus multilocularis Nuclear hormone receptor family member nhr 41 0.0011 0.0006 0.0007
Trichomonas vaginalis sugar transporter, putative 0.0017 0.0067 0.0067
Brugia malayi MH2 domain containing protein 0.0127 0.1175 0.117
Leishmania major hypothetical protein, conserved 0.0057 0.0469 0.0486
Echinococcus granulosus solute carrier family 2 facilitated glucose 0.0056 0.0458 0.056
Entamoeba histolytica Ras guanine nucleotide exchange factor, putative 0.0016 0.005 0.0081
Brugia malayi ERG2 and Sigma1 receptor like protein 0.0953 0.9528 0.9528
Echinococcus multilocularis neuropeptide receptor 0.0019 0.0087 0.0098
Onchocerca volvulus 0.0693 0.6901 0.8424
Loa Loa (eye worm) hypothetical protein 0.0019 0.0087 0.0081
Loa Loa (eye worm) hypothetical protein 0.0019 0.0087 0.0081
Brugia malayi Cathepsin L-like precursor 0.0018 0.0071 0.0065
Plasmodium falciparum acyl carrier protein 0.0014 0.003 0.0129
Plasmodium vivax hypothetical protein, conserved 0.0041 0.0302 0.1302
Echinococcus granulosus COUP TF:Svp nuclear hormone receptor 0.0011 0.0006 0.0008
Mycobacterium leprae PROBABLE POLYKETIDE BETA-KETOACYL SYNTHASE PKS4 0.0021 0.0102 0.049
Trypanosoma brucei glucose transporter 2A 0.0017 0.0067 0.0052
Schistosoma mansoni RNA binding protein 0.0057 0.0469 0.0469
Onchocerca volvulus 0.0041 0.0302 0.0361
Loa Loa (eye worm) hypothetical protein 0.0019 0.0087 0.0081
Trypanosoma cruzi hexose transporter, putative 0.0017 0.0067 0.0052
Trichomonas vaginalis Clan CA, family C1, papain-like cysteine peptidase 0.0018 0.0071 0.0071
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0019 0.0087 0.0087
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0019 0.0087 0.0087
Chlamydia trachomatis DNA topoisomerase I 0.0161 0.1516 1
Mycobacterium tuberculosis Phenolpthiocerol synthesis type-I polyketide synthase PpsB 0.0021 0.0102 0.024
Trypanosoma brucei polo-like protein kinase 0.0619 0.6156 0.6454
Loa Loa (eye worm) hypothetical protein 0.0534 0.529 0.5287
Loa Loa (eye worm) fibroinase 0.0018 0.0071 0.0065
Brugia malayi G-protein coupled receptor 0.0019 0.0087 0.0081
Trypanosoma brucei calcium/calmodulin-dependent protein kinase, putative 0.0019 0.0085 0.0071
Mycobacterium tuberculosis Acyl carrier protein (ACP) MbtL 0.0014 0.003 0.0058
Mycobacterium tuberculosis Phenolpthiocerol synthesis type-I polyketide synthase PpsD 0.0136 0.1265 0.3184
Onchocerca volvulus 0.0022 0.0114 0.0131
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0018 0.0071 0.0071
Schistosoma mansoni opsin-like receptor 0.0019 0.0087 0.0087
Echinococcus multilocularis cathepsin L cysteine protease 0.0018 0.0071 0.008
Mycobacterium leprae PROBABLE FATTY ACID SYNTHASE FAS (FATTY ACID SYNTHETASE) 0.0043 0.0323 0.163
Echinococcus granulosus 7tm_1 domain containing protein 0.0019 0.0087 0.0106
Brugia malayi Calcium/calmodulin-dependent protein kinase type II alpha chain 0.0019 0.0085 0.0079
Toxoplasma gondii Sodium:neurotransmitter symporter family protein 0.0118 0.1081 0.6142
Brugia malayi vesicular acetylcholine transporter unc-17 0.0821 0.8191 0.819
Echinococcus multilocularis 7TM GPCR, rhodopsin 0.0019 0.0087 0.0098
Entamoeba histolytica acyl-CoA synthetase, putative 0.004 0.0292 0.0475
Schistosoma mansoni hypothetical protein 0.0169 0.1599 0.1599
Echinococcus multilocularis SWI:SNF matrix associated 0.0161 0.1516 0.1711
Leishmania major protein kinase, putative 0.0019 0.0085 0.0082
Mycobacterium tuberculosis Meromycolate extension acyl carrier protein AcpM 0.0014 0.003 0.0058
Toxoplasma gondii protein kinase, putative 0.016 0.1514 0.8604
Schistosoma mansoni peptide (FMRFamide/somatostatin)-like receptor 0.0019 0.0087 0.0087
Echinococcus granulosus tm gpcr rhodopsin 0.0019 0.0087 0.0106
Loa Loa (eye worm) hypothetical protein 0.0052 0.042 0.0413
Schistosoma mansoni biogenic amine (dopamine) receptor 0.0019 0.0087 0.0087
Plasmodium falciparum calcium-dependent protein kinase 1 0.0019 0.0085 0.0368
Loa Loa (eye worm) neuropeptide F receptor 0.0019 0.0087 0.0081
Trypanosoma brucei hypothetical protein, conserved 0.0057 0.0469 0.0475
Leishmania major protein kinase, putative,polo-like protein kinase, putative 0.0619 0.6156 0.6458
Echinococcus granulosus cathepsin l1 0.0018 0.0071 0.0087
Echinococcus multilocularis cysteine protease 0.0018 0.0071 0.008
Mycobacterium ulcerans acyl carrier protein 0.0014 0.003 0.0023
Echinococcus multilocularis rhodopsin orphan GPCR 0.0019 0.0087 0.0098
Plasmodium vivax CDK-related protein kinase 6, putative 0.024 0.2319 1
Toxoplasma gondii lysine-tRNA ligase 0.0013 0.0018 0.0101
Echinococcus multilocularis g protein linked acetylcholine receptor gar 2a 0.0019 0.0087 0.0098
Echinococcus granulosus regulator of G protein signaling 7 0.0022 0.0114 0.0139
Echinococcus granulosus AMP dependent ligase 0.0015 0.0041 0.005
Brugia malayi Pre-SET motif family protein 0.0052 0.042 0.0413
Mycobacterium ulcerans fatty acid synthase Fas 0.0043 0.0323 0.0316
Echinococcus multilocularis neuropeptide s receptor 0.0019 0.0087 0.0098
Loa Loa (eye worm) solute carrier family 6 member 4 0.0693 0.6901 0.6899
Brugia malayi Calcitonin receptor-like protein seb-1 0.0534 0.529 0.5287
Mycobacterium ulcerans 3-oxoacyl-(acyl carrier protein) synthase II 0.0034 0.0236 0.0229
Brugia malayi brahma associated protein 60 kDa 0.0161 0.1516 0.1511
Mycobacterium ulcerans multifunctional mycocerosic acid synthase membrane-associated Mas 0.0144 0.1351 0.1345
Schistosoma mansoni neuropeptide receptor 0.0019 0.0087 0.0087
Toxoplasma gondii hypothetical protein 0.0118 0.1081 0.6142
Mycobacterium tuberculosis Probable hydrolase 0.0041 0.0302 0.0746
Loa Loa (eye worm) hypothetical protein 0.0953 0.9528 0.9528
Mycobacterium tuberculosis Polyketide synthase Pks2 0.0132 0.1223 0.3077
Echinococcus multilocularis neuropeptide Y receptor 0.0019 0.0087 0.0098
Onchocerca volvulus 0.0161 0.1516 0.1845
Schistosoma mansoni protein kinase 0.0019 0.0085 0.0085
Loa Loa (eye worm) hypothetical protein 0.0019 0.0087 0.0081
Onchocerca volvulus 0.0018 0.0071 0.0079
Echinococcus granulosus cathepsin L cysteine proteinase 0.0018 0.0071 0.0087
Mycobacterium ulcerans acyl-CoA synthetase 0.0026 0.0153 0.0147
Loa Loa (eye worm) hypothetical protein 0.0019 0.0087 0.0081
Schistosoma mansoni myosin xvIII 0.0019 0.0087 0.0087
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0068 0.0577 0.0589
Brugia malayi hypothetical protein 0.0019 0.0087 0.0081
Echinococcus granulosus g protein coupled receptor 0.0019 0.0087 0.0106
Mycobacterium ulcerans lipase LipD 0.0041 0.0302 0.0295
Mycobacterium ulcerans lipoprotein LpqF 0.0193 0.1844 0.1838
Mycobacterium tuberculosis Phenolpthiocerol synthesis type-I polyketide synthase PpsC 0.0136 0.1265 0.3184
Loa Loa (eye worm) hypothetical protein 0.0019 0.0087 0.0081
Plasmodium vivax hypothetical protein, conserved 0.0161 0.1516 0.6538
Schistosoma mansoni serine/threonine protein kinase 0.0619 0.6156 0.6156
Onchocerca volvulus 0.0057 0.0469 0.0565
Echinococcus granulosus g protein coupled receptor 0.0019 0.0087 0.0106
Schistosoma mansoni nuclear receptor 2DBD-gamma 0.0011 0.0006 0.0006
Brugia malayi hypothetical protein 0.0019 0.0087 0.0081
Echinococcus granulosus cGMP dependent protein kinase 1 0.0013 0.002 0.0024
Brugia malayi Cathepsin L-like precursor 0.0018 0.0071 0.0065
Entamoeba histolytica acyl-CoA synthetase, putative 0.0015 0.0041 0.0066
Mycobacterium leprae Polyketide synthase Pks13 0.0203 0.1945 1
Onchocerca volvulus 0.0041 0.0302 0.0361
Mycobacterium tuberculosis Probable fatty-acid-CoA ligase FadD9 (fatty-acid-CoA synthetase) (fatty-acid-CoA synthase) 0.0015 0.0041 0.0085
Brugia malayi acyl carrier protein, mitochondrial precursor, putative 0.0014 0.003 0.0023
Mycobacterium ulcerans polyketide synthase 0.0136 0.1265 0.1259
Entamoeba histolytica protein kinase, putative 0.0019 0.0085 0.0138
Mycobacterium ulcerans long-chain fatty-acid CoA ligase 0.0026 0.0153 0.0147
Onchocerca volvulus 0.0057 0.0469 0.0565
Loa Loa (eye worm) hypothetical protein 0.0013 0.0018 0.0011
Loa Loa (eye worm) RasGEF domain-containing protein 0.0016 0.005 0.0043
Echinococcus multilocularis Acyl carrier protein, mitochondrial 0.0014 0.003 0.0034
Schistosoma mansoni zinc finger protein 0.0057 0.0469 0.0469
Mycobacterium tuberculosis Probable fatty-acid-CoA ligase FadD5 (fatty-acid-CoA synthetase) (fatty-acid-CoA synthase) 0.0018 0.0076 0.0176
Schistosoma mansoni glutamyl-tRNA synthetase cytoplasmic (glutamate--tRNA ligase) (glurs) 0.0017 0.0061 0.0061
Trichomonas vaginalis glucosylceramidase, putative 0.009 0.0798 0.0798
Loa Loa (eye worm) cysteine protease 0.0018 0.0071 0.0065
Toxoplasma gondii facilitative glucose transporter GT1 0.0056 0.0458 0.2604
Loa Loa (eye worm) hypothetical protein 0.0019 0.0087 0.0081
Trichomonas vaginalis CAMK family protein kinase 0.0619 0.6156 0.6156
Trichomonas vaginalis Clan CA, family C1, cathepsin L or K-like cysteine peptidase 0.0018 0.0071 0.0071
Leishmania major cathepsin L-like protease 0.0018 0.0071 0.0068
Brugia malayi RasGEF domain containing protein 0.0016 0.005 0.0043
Trichomonas vaginalis penicillin-binding protein, putative 0.0041 0.0302 0.0302
Onchocerca volvulus 0.0018 0.0071 0.0079
Echinococcus granulosus rhodopsin orphan GPCR 0.0019 0.0087 0.0106
Echinococcus granulosus segment polarity protein dishevelled 0.0022 0.0114 0.0139
Trypanosoma brucei glucose transporter, putative 0.0017 0.0067 0.0052
Plasmodium falciparum calcium-dependent protein kinase 2 0.0019 0.0085 0.0368
Schistosoma mansoni biogenic amine (dopamine) receptor 0.0019 0.0087 0.0087
Brugia malayi AMP-binding enzyme family protein 0.0026 0.0153 0.0147
Loa Loa (eye worm) AGC/PKG protein kinase 0.0013 0.002 0.0013
Trypanosoma brucei THT1 - hexose transporter, putative 0.0017 0.0067 0.0052
Schistosoma mansoni tar DNA-binding protein 0.0129 0.1198 0.1198
Loa Loa (eye worm) hypothetical protein 0.0447 0.4415 0.4412
Mycobacterium tuberculosis Phenolpthiocerol synthesis type-I polyketide synthase PpsE 0.0021 0.0102 0.024
Trypanosoma brucei Acyl carrier protein, mitochondrial 0.0014 0.003 0.0013
Loa Loa (eye worm) PLK/PLK1 protein kinase 0.0619 0.6156 0.6154
Trypanosoma cruzi cysteine peptidase, putative 0.0068 0.0577 0.0589
Toxoplasma gondii cathepsin CPL 0.0018 0.0071 0.0405
Schistosoma mansoni serine/threonine protein kinase 0.0013 0.002 0.002
Echinococcus multilocularis isocitrate dehydrogenase 0.0094 0.0845 0.0953
Mycobacterium ulcerans long-chain-fatty-acid--CoA ligase 0.0026 0.0153 0.0147
Schistosoma mansoni peptide (FMRFamide/neurokinin-3)-like receptor 0.0019 0.0087 0.0087
Schistosoma mansoni thyroid hormone receptor 0.0011 0.0006 0.0006
Entamoeba histolytica Ras guanine nucleotide exchange factor, putative 0.0016 0.005 0.0081
Schistosoma mansoni histamine h1 receptor 0.0019 0.0087 0.0087
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0018 0.0071 0.0071
Schistosoma mansoni protein kinase 0.0019 0.0085 0.0085
Loa Loa (eye worm) RNA binding protein 0.0129 0.1198 0.1193
Mycobacterium leprae PROBABLE CONSERVED LIPOPROTEIN LPQF 0.0193 0.1844 0.9478
Loa Loa (eye worm) SWIB/MDM2 domain-containing protein 0.0161 0.1516 0.1511
Onchocerca volvulus Vesicular acetylcholine transporter homolog 0.0821 0.8191 1
Echinococcus granulosus cGMP dependent protein kinase 1 0.0013 0.002 0.0024
Trypanosoma cruzi Zn-finger in Ran binding protein and others, putative 0.0057 0.0469 0.0475
Loa Loa (eye worm) hypothetical protein 0.0041 0.0302 0.0296
Schistosoma mansoni tar DNA-binding protein 0.0129 0.1198 0.1198
Schistosoma mansoni neuropeptide F-like receptor 0.0019 0.0087 0.0087
Mycobacterium leprae PHENOLPTHIOCEROL SYNTHESIS TYPE-I POLYKETIDE SYNTHASE PPSD 0.0136 0.1265 0.6493
Brugia malayi N-terminal motif family protein 0.0447 0.4415 0.4412
Mycobacterium ulcerans polyketide synthase MbtC 0.0034 0.0236 0.0229
Echinococcus granulosus Nuclear hormone receptor family member nhr 41 0.0011 0.0006 0.0008
Onchocerca volvulus Cathepsin L homolog 0.0018 0.0071 0.0079
Mycobacterium tuberculosis Polyketide synthetase MbtC (polyketide synthase) 0.0047 0.0363 0.0902
Schistosoma mansoni glucose transport protein 0.0056 0.0458 0.0458
Schistosoma mansoni dishevelled 0.0022 0.0114 0.0114
Loa Loa (eye worm) hypothetical protein 0.0019 0.0085 0.0079
Echinococcus granulosus uncharacterized sodium dependent transporter 0.0118 0.1081 0.132
Mycobacterium tuberculosis Probable polyketide synthase Pks5 0.0132 0.1223 0.3077
Loa Loa (eye worm) hypothetical protein 0.0019 0.0087 0.0081
Brugia malayi G protein-coupled receptor 0.0019 0.0087 0.0081
Schistosoma mansoni thyrotropin-releasing hormone receptor 0.0019 0.0087 0.0087
Brugia malayi hypothetical protein 0.0019 0.0087 0.0081
Echinococcus granulosus tar DNA binding protein 0.0129 0.1198 0.1463
Schistosoma mansoni methyltransferase-related 0.0041 0.0305 0.0305
Loa Loa (eye worm) glutaminase 0.0999 1 1
Mycobacterium ulcerans Type I modular polyketide synthase 0.0136 0.1265 0.1259
Mycobacterium ulcerans lysyl-tRNA synthetase 0.0013 0.0018 0.0011
Echinococcus multilocularis nuclear receptor 2DBD gamma 0.0011 0.0006 0.0007
Plasmodium vivax acyl-CoA synthetase, putative 0.0019 0.0087 0.0375
Echinococcus granulosus Upstream activation factor subunit UAF30 0.0161 0.1516 0.1851
Echinococcus granulosus cathepsin l cysteine peptidase 0.0018 0.0071 0.0087
Echinococcus multilocularis rhodopsin orphan GPCR 0.0019 0.0087 0.0098
Echinococcus multilocularis expressed conserved protein 0.0013 0.002 0.0022
Trypanosoma cruzi WLM domain containing protein, putative 0.0057 0.0469 0.0475
Mycobacterium ulcerans long-chain-fatty-acid-CoA ligase 0.0026 0.0153 0.0147
Onchocerca volvulus 0.0019 0.0087 0.0099
Echinococcus multilocularis chromobox protein 1 0.0059 0.0491 0.0554
Toxoplasma gondii DNA topoisomerase domain-containing protein 0.0161 0.1516 0.8615
Onchocerca volvulus 0.0118 0.1081 0.1313
Loa Loa (eye worm) hypothetical protein 0.0019 0.0087 0.0081
Trypanosoma brucei glucose transporter, putative 0.0017 0.0067 0.0052
Echinococcus granulosus 5'partial|histone lysine N methyltransferase SETDB2 0.005 0.04 0.0488
Brugia malayi gonadotropin-releasing hormone receptor 2 0.0019 0.0087 0.0081
Leishmania major beta-ketoacyl synthase family protein, putative,3-oxoacyl-acyl carrier protein synthase ii, putative 0.0034 0.0236 0.0241
Trypanosoma cruzi beta-ketoacyl synthase family protein, putative 0.0034 0.0236 0.023
Loa Loa (eye worm) hypothetical protein 0.0019 0.0087 0.0081
Schistosoma mansoni glutamyl-tRNA synthetase cytoplasmic (glutamate--tRNA ligase) (glurs) 0.0017 0.0061 0.0061
Brugia malayi Dopamine receptor protein 1 0.0019 0.0087 0.0081
Onchocerca volvulus 0.0244 0.236 0.2875
Trypanosoma cruzi hypothetical protein, conserved 0.0057 0.0469 0.0475
Plasmodium falciparum proline--tRNA ligase 0.002 0.0089 0.0386
Echinococcus granulosus rhodopsin orphan GPCR 0.0019 0.0087 0.0106
Schistosoma mansoni coup transcription factor 0.0011 0.0006 0.0006
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0018 0.0071 0.0071
Trichomonas vaginalis isocitrate dehydrogenase, putative 0.0011 0.0007 0.0007
Brugia malayi hypothetical protein 0.0019 0.0087 0.0081
Echinococcus multilocularis glutamyl tRNA synthetase cytoplasmic 0.0017 0.0061 0.0069
Loa Loa (eye worm) hypothetical protein 0.0438 0.4324 0.4321
Echinococcus multilocularis AMP dependent ligase 0.0015 0.0041 0.0046
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0019 0.0087 0.0087
Plasmodium falciparum ataxin-2 like protein, putative 0.0185 0.176 0.7589
Echinococcus multilocularis serotonin transporter 0.0693 0.6901 0.7787
Echinococcus multilocularis Nuclear pore complex protein Nup153 0.0057 0.0469 0.0529
Trichomonas vaginalis Clan CA, family C1, cathepsin L or K-like cysteine peptidase 0.0018 0.0071 0.0071
Trypanosoma brucei beta lactamase 0.0193 0.1844 0.192
Brugia malayi Bifunctional aminoacyl-tRNA synthetase 0.0017 0.0061 0.0055
Loa Loa (eye worm) hypothetical protein 0.0021 0.0102 0.0095
Echinococcus granulosus rap guanine nucleotide exchange factor 6 0.0016 0.005 0.0061
Echinococcus multilocularis General substrate transporter 0.0048 0.0379 0.0427
Onchocerca volvulus Heterochromatin protein 1 homolog 0.0033 0.0227 0.027
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0068 0.0577 0.0589
Schistosoma mansoni hypothetical protein 0.0019 0.0087 0.0087
Leishmania major 4-coumarate:coa ligase-like protein 0.0026 0.0153 0.0154
Mycobacterium ulcerans class a beta-lactamase, BlaC 0.0402 0.3959 0.3955
Trypanosoma brucei THT1 - hexose transporter, putative 0.0017 0.0067 0.0052
Onchocerca volvulus 0.0026 0.0153 0.0179
Onchocerca volvulus 0.0019 0.0087 0.0099
Trypanosoma cruzi cysteine peptidase, putative 0.0018 0.0071 0.0056
Mycobacterium leprae PHENOLPTHIOCEROL SYNTHESIS TYPE-I POLYKETIDE SYNTHASE PPSA 0.0136 0.1265 0.6493
Onchocerca volvulus 0.0021 0.0107 0.0123
Echinococcus granulosus acyl carrier protein mitochondrial 0.0014 0.003 0.0036
Echinococcus granulosus ring and YY1 binding protein 0.0057 0.0469 0.0573
Loa Loa (eye worm) brahma associated protein 0.0161 0.1516 0.1511

Activities

No activities found for this compound.

Phenotypes

Whole-cell/tissue/organism interactions

We have no records of whole-cell/tissue assays done with this compound What does this mean?

Many chemical entities in TDR Targets come from high-throughput screenings with whole cells or tissue samples, and not all assayed compounds have been tested against a single a single target protein, probably because they get ruled out during screening process. Even if these compounds may have not been of interest in the original screening, they may come as interesting leads for other screening assays. Furthermore, we may be able to propose drug-target associations using chemical similarities and network patterns.

Annotated phenotypes:

We have no manually annotated phenotypes for this drug. What does this mean? / Care to help?
In TDR Targets, information about phenotypes that are caused by drugs, or by genetic manipulation of cells (e.g. gene knockouts or knockdowns) is manually curated from the literature. These descriptions help to describe the potential of the target for drug development. If no information is available for this gene or if the information is incomplete, this may mean that i) the papers containing this information either appeared after the curation effort for this organism was carried out or they were inadvertently missed by curators; or that ii) the curation effort for this organism has not yet started.
 
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External resources for this compound

Bibliographic References

No literature references available for this target.

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