Detailed information for compound 712163

Basic information

Technical information
  • TDR Targets ID: 712163
  • Name: N-(4-bromophenyl)-5-nitropyrimidine-4,6-diami ne
  • MW: 310.107 | Formula: C10H8BrN5O2
  • H donors: 2 H acceptors: 4 LogP: 3.35 Rotable bonds: 3
    Rule of 5 violations (Lipinski): 1
  • SMILES: Brc1ccc(cc1)Nc1ncnc(c1[N+](=O)[O-])N
  • InChi: 1S/C10H8BrN5O2/c11-6-1-3-7(4-2-6)15-10-8(16(17)18)9(12)13-5-14-10/h1-5H,(H3,12,13,14,15)
  • InChiKey: HHDWZWUTFPJBER-UHFFFAOYSA-N  


Substructure search Similarity search

Network

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Synonyms

  • N-(4-bromophenyl)-5-nitro-pyrimidine-4,6-diamine
  • (6-amino-5-nitro-pyrimidin-4-yl)-(4-bromophenyl)amine
  • ZINC03912732

Targets

Known targets for this compound

No curated genes were found associated with this compound

Predicted pathogen targets for this compound

By orthology
No druggable targets predicted by orthology data
By sequence similarity to non orthologous known druggable targets
No druggable targets predicted by sequence similarity
Obtained from network model

Ranking Plot

Putative Targets List

Species Potential target Raw Global Species
Trichomonas vaginalis Clan CA, family C1, cathepsin L or K-like cysteine peptidase 0.0034 0.045 0.2292
Trichomonas vaginalis Clan CA, family C1, papain-like cysteine peptidase 0.0034 0.045 0.2292
Echinococcus multilocularis Smad4 0.0016 0.0068 0.0085
Mycobacterium ulcerans lipase LipD 0.0076 0.133 1
Mycobacterium tuberculosis Possible cytochrome P450 135A1 Cyp135A1 0.0015 0.0031 0.0006
Trypanosoma cruzi Phosphatidylinositol 3-kinase tor1 0.0106 0.1962 0.7854
Brugia malayi MAP kinase sur-1 0.0052 0.0815 0.1675
Leishmania major heat shock protein 83-1 0.0033 0.0424 0.1669
Echinococcus granulosus intermediate filament protein 0.0026 0.0282 0.0393
Leishmania major cathepsin L-like protease 0.0034 0.045 0.177
Echinococcus multilocularis solute carrier family 2 facilitated glucose 0.0102 0.1886 0.2704
Echinococcus multilocularis TGF beta signal transducer SmadC 0.0016 0.0068 0.0085
Mycobacterium tuberculosis Putative ferredoxin reductase 0.0105 0.1949 0.1929
Schistosoma mansoni cathepsin F (C01 family) 0.0023 0.0209 0.0288
Mycobacterium ulcerans dihydrolipoamide dehydrogenase, LpdB 0.0016 0.0059 0.0262
Trypanosoma cruzi cysteine peptidase (N-terminal), putative 0.0018 0.0096 0.0385
Loa Loa (eye worm) ctsf protein 0.0034 0.045 0.0735
Plasmodium falciparum major facilitator superfamily domain-containing protein, putative 0.0014 0.0025 0.0018
Entamoeba histolytica prolyl-tRNA synthetase, putative 0.0031 0.037 0.1728
Trichomonas vaginalis Clan CA, family C1, papain-like cysteine peptidase 0.0034 0.045 0.2292
Onchocerca volvulus Cathepsin L homolog 0.0034 0.045 0.3337
Mycobacterium tuberculosis Probable cytochrome P450 128 Cyp128 0.0015 0.0031 0.0006
Trichomonas vaginalis sugar transporter, putative 0.0014 0.0025 0.0128
Toxoplasma gondii pyruvate dehydrogenase complex subunit PDH-E3II 0.0016 0.0059 0.0086
Onchocerca volvulus Putative transporter 0.0014 0.0025 0.0122
Leishmania major heat shock protein 83-1 0.0033 0.0424 0.1669
Trypanosoma brucei ubiquitin carboxyl-terminal hydrolase, putative 0.0074 0.1291 0.5151
Brugia malayi Cathepsin L-like precursor 0.0023 0.0209 0.0415
Mycobacterium leprae conserved hypothetical protein 0.0076 0.133 0.5994
Schistosoma mansoni glutamyl-tRNA synthetase cytoplasmic (glutamate--tRNA ligase) (glurs) 0.0031 0.037 0.052
Trichomonas vaginalis sugar transporter, putative 0.0014 0.0025 0.0128
Echinococcus granulosus geminin 0.0341 0.6948 1
Echinococcus granulosus aldehyde dehydrogenase mitochondrial 0.0062 0.1035 0.1479
Plasmodium vivax vivapain-3 0.0018 0.0096 0.0098
Leishmania major cytochrome p450-like protein 0.0032 0.0408 0.1602
Onchocerca volvulus 0.0034 0.045 0.3337
Toxoplasma gondii protein kinase, putative 0.0289 0.5847 1
Onchocerca volvulus Cathepsin L homolog 0.0034 0.045 0.3337
Mycobacterium tuberculosis Lysyl-tRNA synthetase 2 LysX 0.0019 0.0131 0.0106
Trichomonas vaginalis sugar transporter, putative 0.0014 0.0025 0.0128
Trichomonas vaginalis ap endonuclease, putative 0.0019 0.0128 0.0652
Entamoeba histolytica cysteine protease, putative 0.0018 0.0096 0.0417
Loa Loa (eye worm) hypothetical protein 0.0068 0.1168 0.1908
Mycobacterium tuberculosis NADPH-dependent mycothiol reductase Mtr 0.0046 0.0698 0.0674
Plasmodium falciparum calcium-dependent protein kinase 2 0.0032 0.0394 0.0432
Entamoeba histolytica hypothetical protein 0.002 0.0145 0.0649
Brugia malayi heat shock protein 90 0.0033 0.0424 0.0864
Trichomonas vaginalis sugar transporter, putative 0.0014 0.0025 0.0128
Onchocerca volvulus 0.0014 0.0025 0.0122
Echinococcus granulosus heat shock protein 90 0.0026 0.0281 0.0392
Leishmania major lipophosphoglycan biosynthetic protein, putative,heat shock protein 90, putative,glucose regulated protein 94, putative 0.0026 0.0281 0.1093
Schistosoma mansoni smad 0.0016 0.0068 0.0085
Mycobacterium ulcerans dihydrolipoamide dehydrogenase 0.0016 0.0059 0.0262
Trichomonas vaginalis sugar transporter, putative 0.0014 0.0025 0.0128
Echinococcus multilocularis guanine nucleotide binding protein G(s) subunit 0.0089 0.1618 0.2319
Brugia malayi Cytochrome P450 family protein 0.0032 0.0408 0.0829
Brugia malayi Cytochrome P450 family protein 0.0015 0.0031 0.0045
Leishmania major myo-inositol/proton symporter (MIT) 0.0014 0.0025 0.0065
Trypanosoma brucei mitogen activated protein kinase 4, putative 0.0052 0.0815 0.3237
Schistosoma mansoni ataxia telangiectasia mutated (atm) 0.002 0.0145 0.0195
Toxoplasma gondii calcium-dependent protein kinase CDPK3 0.0032 0.0394 0.0659
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0131 0.2498 1
Trichomonas vaginalis PIKK family atypical protein kinase 0.0069 0.1176 0.5992
Trichomonas vaginalis PIKK family atypical protein kinase 0.0062 0.1047 0.5335
Mycobacterium ulcerans cytochrome P450 142A3 Cyp142A3 0.0015 0.0031 0.0042
Echinococcus multilocularis diuretic hormone 44 receptor GPRdih2 0.0032 0.0391 0.055
Trichomonas vaginalis sugar transporter, putative 0.0014 0.0025 0.0128
Onchocerca volvulus 0.0014 0.0025 0.0122
Trypanosoma brucei GTP-binding nuclear protein rtb2, putative 0.0021 0.0162 0.0614
Loa Loa (eye worm) heat shock protein 90 0.0033 0.0424 0.0693
Entamoeba histolytica hypothetical protein 0.0112 0.2099 1
Echinococcus multilocularis cathepsin L 0.0018 0.0096 0.0126
Trypanosoma brucei phosphatidylinositol 3-related kinase, putative 0.0035 0.0472 0.1861
Trypanosoma brucei heat shock protein, putative 0.0033 0.0424 0.1669
Trypanosoma brucei apurinic/apyrimidinic endonuclease, putative 0.0019 0.0128 0.0477
Schistosoma mansoni glucose transport protein 0.0102 0.1886 0.2704
Brugia malayi GTP-binding regulatory protein Gs alpha-S chain, putative 0.0089 0.1618 0.3345
Trypanosoma brucei glucose transporter, putative 0.0032 0.0392 0.1539
Leishmania major dihydrolipoamide dehydrogenase, putative 0.0016 0.0059 0.0202
Echinococcus granulosus solute carrier family 22 0.0014 0.0025 0.0023
Leishmania major heat shock protein 83-1 0.0033 0.0424 0.1669
Leishmania major heat shock protein 83-1 0.0033 0.0424 0.1669
Trichomonas vaginalis PIKK family atypical protein kinase 0.0079 0.1388 0.7073
Echinococcus granulosus ubiquitin specific protease 41 0.0074 0.1291 0.1848
Toxoplasma gondii HEAT repeat-containing protein 0.0028 0.032 0.0533
Leishmania major heat shock protein 83-1 0.0033 0.0424 0.1669
Trypanosoma cruzi trypanothione reductase, putative 0.0016 0.0059 0.0237
Echinococcus multilocularis Basic leucine zipper (bZIP) transcription 0.0112 0.2099 0.3012
Brugia malayi MH1 domain containing protein 0.0016 0.0068 0.0123
Leishmania major phosphatidylinositol 3-kinase, putative 0.0035 0.0472 0.1861
Echinococcus multilocularis serine:threonine protein kinase SMG1 0.002 0.0145 0.0195
Loa Loa (eye worm) cytochrome P450 family protein 0.0035 0.0455 0.0744
Entamoeba histolytica cysteine protease, putative 0.0018 0.0096 0.0417
Loa Loa (eye worm) hypothetical protein 0.0028 0.032 0.0523
Entamoeba histolytica FKBP-rapamycin associated protein (FRAP), putative 0.0106 0.1962 0.9345
Loa Loa (eye worm) cytoplasmic intermediate filament protein 0.0014 0.0021 0.0035
Echinococcus multilocularis General substrate transporter 0.0088 0.1581 0.2266
Schistosoma mansoni gabp alpha 0.0074 0.1286 0.184
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0034 0.045 0.2292
Brugia malayi Phosphatidylinositol 3- and 4-kinase family protein 0.002 0.0145 0.0282
Leishmania major glucose transporter, lmgt3 0.0032 0.0392 0.1539
Leishmania major cathepsin L-like protease 0.0034 0.045 0.177
Onchocerca volvulus 0.0034 0.045 0.3337
Leishmania major GTP-binding protein, putative 0.0021 0.0162 0.0614
Loa Loa (eye worm) hypothetical protein 0.0014 0.0025 0.0041
Trichomonas vaginalis sugar transporter, putative 0.0014 0.0025 0.0128
Leishmania major cytochrome p450-like protein 0.0015 0.0031 0.0087
Trypanosoma cruzi mitogen-activated protein kinase 11, putative 0.0052 0.0815 0.3262
Plasmodium vivax hexose transporter 0.0102 0.1886 0.2106
Trichomonas vaginalis glucose transporter, putative 0.0032 0.0392 0.1999
Toxoplasma gondii NADPH-glutathione reductase 0.0016 0.0059 0.0086
Schistosoma mansoni ubiquitin-specific peptidase 8 (C19 family) 0.0074 0.1291 0.1848
Loa Loa (eye worm) sugar transporter 0.0102 0.1886 0.308
Schistosoma mansoni glucose transporter 0.0014 0.0025 0.0023
Mycobacterium ulcerans lysyl-tRNA synthetase 0.0023 0.0204 0.1371
Trypanosoma cruzi cysteine peptidase, putative 0.0131 0.2498 1
Trypanosoma brucei bifunctional aminoacyl-tRNA synthetase, putative 0.0036 0.0478 0.1883
Trypanosoma cruzi hexose transporter, putative 0.0014 0.0025 0.0101
Mycobacterium ulcerans cytochrome P450 191A3 Cyp191A3 0.0015 0.0031 0.0042
Trichomonas vaginalis heat shock protein, putative 0.0014 0.0009 0.0046
Schistosoma mansoni smad1 5 8 and 0.0016 0.0068 0.0085
Mycobacterium ulcerans fusion of enoyl-CoA hydratase, EchA21 and lipase, LipE 0.0076 0.133 1
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0131 0.2498 1
Echinococcus multilocularis calcium:calmodulin dependent protein kinase type 0.0032 0.0393 0.0554
Entamoeba histolytica hypothetical protein 0.0023 0.0207 0.0947
Echinococcus granulosus serine protein kinase ATM 0.002 0.0145 0.0195
Trichomonas vaginalis lysyl-tRNA synthetase, putative 0.0023 0.0204 0.104
Schistosoma mansoni glucose transport protein 0.0102 0.1886 0.2704
Schistosoma mansoni Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) 0.0089 0.1618 0.2319
Trypanosoma cruzi heat shock protein 90, putative 0.002 0.0136 0.0545
Trypanosoma brucei heat shock protein 90, putative 0.0033 0.0424 0.1669
Wolbachia endosymbiont of Brugia malayi heat shock protein 90 0.0026 0.0281 1
Onchocerca volvulus 0.0014 0.0025 0.0122
Brugia malayi exodeoxyribonuclease III family protein 0.0019 0.0128 0.0247
Echinococcus granulosus cathepsin l1 0.0034 0.045 0.0635
Trypanosoma cruzi dihydrolipoamide dehydrogenase, putative 0.0016 0.0059 0.0237
Loa Loa (eye worm) CAMK/CAMK2 protein kinase 0.0032 0.0393 0.0642
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0018 0.0096 0.035
Plasmodium vivax GTP-binding nuclear protein RAN/TC4, putative 0.0021 0.0162 0.0172
Trypanosoma cruzi importin beta-1 subunit, putative 0.0023 0.0207 0.0828
Onchocerca volvulus 0.0014 0.0025 0.0122
Entamoeba histolytica cysteine protease, putative 0.0018 0.0096 0.0417
Trichomonas vaginalis Clan CA, family C1, papain-like cysteine peptidase 0.0034 0.045 0.2292
Brugia malayi hypothetical protein 0.0014 0.0025 0.0033
Mycobacterium leprae Probable prolyl tRNA synthetase ProS 0.0031 0.037 0.1567
Echinococcus multilocularis calcium:calmodulin dependent protein kinase type 0.0032 0.0393 0.0554
Trypanosoma brucei Lanosterol 14-alpha demethylase 0.0015 0.0031 0.0087
Schistosoma mansoni fkbp-rapamycin associated protein 0.002 0.0145 0.0195
Trichomonas vaginalis conserved hypothetical protein 0.0022 0.0193 0.0984
Mycobacterium ulcerans heat shock protein 90 0.0026 0.0281 0.1962
Trypanosoma cruzi trypanothione reductase, putative 0.0046 0.0698 0.2793
Toxoplasma gondii ABC1 family protein 0.0076 0.133 0.2262
Entamoeba histolytica cysteine protease, putative 0.0018 0.0096 0.0417
Trypanosoma brucei sugar transporter, putative 0.0014 0.0025 0.0065
Echinococcus granulosus Peptidase C19 ubiquitin carboxyl terminal hydrolase 2 0.0074 0.1291 0.1848
Schistosoma mansoni ap endonuclease 0.0019 0.0128 0.0171
Trichomonas vaginalis CMGC family protein kinase 0.0052 0.0815 0.4153
Mycobacterium ulcerans cytochrome P450 185A4 Cyp185A4 0.0032 0.0408 0.2934
Echinococcus granulosus calcium:calmodulin dependent protein kinase type 1 0.0032 0.0393 0.0554
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0131 0.2498 1
Trypanosoma brucei glucose transporter 2A 0.0032 0.0392 0.1539
Loa Loa (eye worm) intermediate filament tail domain-containing protein 0.0026 0.0282 0.0461
Entamoeba histolytica cysteine protease, putative 0.0018 0.0096 0.0417
Leishmania major apurinic/apyrimidinic endonuclease-redox protein 0.0019 0.0128 0.0477
Mycobacterium tuberculosis Probable cytochrome P450 125 Cyp125 0.0015 0.0031 0.0006
Trypanosoma cruzi sugar transporter, putative 0.0014 0.0025 0.0101
Schistosoma mansoni hypothetical protein 0.0341 0.6948 1
Echinococcus multilocularis thioredoxin glutathione reductase 0.0046 0.0698 0.0992
Brugia malayi Major Facilitator Superfamily protein 0.0014 0.0025 0.0033
Trypanosoma cruzi phosphatidylinositol 3-kinase, putative 0.002 0.0145 0.0579
Plasmodium vivax dihydrolipoyl dehydrogenase, mitochondrial, putative 0.0016 0.0059 0.0056
Leishmania major acetoin dehydrogenase e3 component-like protein 0.0016 0.0059 0.0202
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0131 0.2498 1
Trichomonas vaginalis PIKK family atypical protein kinase 0.0106 0.1962 1
Brugia malayi Importin beta-1 subunit 0.0028 0.032 0.0647
Echinococcus granulosus ubiquitin carboxyl terminal hydrolase 8 0.0074 0.1291 0.1848
Mycobacterium leprae PROBABLE CHAPERONE PROTEIN HTPG (HEAT SHOCK PROTEIN) (HSP90 FAMILY PROTEIN) (HIGH TEMPERATURE PROTEIN G) 0.0026 0.0281 0.1156
Schistosoma mansoni sugar transporter 0.0014 0.0025 0.0023
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0131 0.2498 1
Mycobacterium ulcerans cytochrome P450 150A6 Cyp150A6 0.0015 0.0031 0.0042
Leishmania major hypothetical protein, conserved 0.0076 0.133 0.5306
Trichomonas vaginalis Clan CA, family C1, papain-like cysteine peptidase 0.0034 0.045 0.2292
Loa Loa (eye worm) calcium/calmodulin-dependent protein kinase ID 0.0032 0.0393 0.0642
Mycobacterium tuberculosis Probable cytochrome P450 143 Cyp143 0.0015 0.0031 0.0006
Trypanosoma brucei target of rapamycin kinase 3, putative 0.0084 0.1505 0.6011
Trypanosoma cruzi heat shock protein 85, putative 0.0033 0.0424 0.1699
Loa Loa (eye worm) GTP-binding nuclear protein RAN/TC4 0.0021 0.0162 0.0265
Entamoeba histolytica cysteine protease, putative 0.0018 0.0096 0.0417
Echinococcus multilocularis heat shock protein 90 0.0026 0.0281 0.0392
Trypanosoma cruzi GTP-binding nuclear protein rtb2, putative 0.0021 0.0162 0.0649
Mycobacterium ulcerans hypothetical protein 0.0076 0.133 1
Leishmania major glucose transporter, lmgt1 0.0032 0.0392 0.1539
Trypanosoma cruzi dihydrolipoyl dehydrogenase, putative 0.0016 0.0059 0.0237
Mycobacterium ulcerans aldehyde dehydrogenase 0.0062 0.1035 0.7744
Loa Loa (eye worm) hypothetical protein 0.0014 0.0025 0.0041
Loa Loa (eye worm) hypothetical protein 0.0014 0.0025 0.0041
Leishmania major cysteine peptidase A (CPA) 0.0034 0.045 0.177
Trichomonas vaginalis sugar transporter, putative 0.0014 0.0025 0.0128
Loa Loa (eye worm) fli-1 protein 0.0224 0.4472 0.7306
Trypanosoma cruzi hexose transporter, putative 0.0017 0.0088 0.0351
Mycobacterium tuberculosis Probable lipase LipE 0.0076 0.133 0.1308
Trypanosoma brucei dihydrolipoamide dehydrogenase, point mutation 0.0016 0.0059 0.0202
Trichomonas vaginalis glutathione reductase, putative 0.0016 0.0059 0.0302
Brugia malayi bifunctional aminoacyl-tRNA synthetase 0.0031 0.037 0.0751
Trypanosoma brucei dihydrolipoamide dehydrogenase 0.0016 0.0059 0.0202
Loa Loa (eye worm) hypothetical protein 0.0063 0.1059 0.173
Toxoplasma gondii prolyl-tRNA synthetase (ProRS) 0.0036 0.0478 0.0803
Trypanosoma cruzi dihydrolipoamide dehydrogenase, putative 0.0016 0.0059 0.0237
Loa Loa (eye worm) hypothetical protein 0.0031 0.037 0.0605
Mycobacterium tuberculosis Probable soluble pyridine nucleotide transhydrogenase SthA (STH) (NAD(P)(+) transhydrogenase [B-specific]) (nicotinamide nucleot 0.0016 0.0059 0.0034
Entamoeba histolytica cysteine proteinase, putative 0.0023 0.0209 0.0955
Echinococcus granulosus heat shock protein 90 0.0033 0.0424 0.0599
Echinococcus granulosus solute carrier family 2 facilitated glucose 0.0102 0.1886 0.2704
Echinococcus granulosus solute carrier family 22 0.0014 0.0025 0.0023
Entamoeba histolytica cysteine protease, putative 0.0034 0.045 0.2108
Onchocerca volvulus 0.0014 0.0025 0.0122
Trichomonas vaginalis PIKK family atypical protein kinase 0.0079 0.1388 0.7073
Mycobacterium ulcerans cytochrome P450 144A4 Cyp144A4 0.0015 0.0031 0.0042
Brugia malayi Cathepsin L-like precursor 0.0034 0.045 0.0916
Leishmania major dihydrolipoamide dehydrogenase, putative 0.0016 0.0059 0.0202
Trichomonas vaginalis PIKK family atypical protein kinase 0.0079 0.1388 0.7073
Brugia malayi hypothetical protein 0.0014 0.0025 0.0033
Entamoeba histolytica cysteine proteinase 1, putative 0.0018 0.0096 0.0417
Plasmodium vivax calcium-dependent protein kinase 4, putative 0.0032 0.0394 0.0432
Schistosoma mansoni phosphatidylinositol 3-and 4-kinase 0.0035 0.0472 0.0668
Trypanosoma cruzi cysteine peptidase, putative 0.0131 0.2498 1
Brugia malayi Calcium/calmodulin-dependent protein kinase type II alpha chain 0.0032 0.0393 0.0799
Loa Loa (eye worm) hypothetical protein 0.0076 0.133 0.2172
Brugia malayi Sugar transporter family protein 0.0014 0.0025 0.0033
Leishmania major prolyl-tRNA synthetase, putative,bifunctional aminoacyl-tRNA synthetase, putative 0.0036 0.0478 0.1883
Echinococcus granulosus survival motor neuron protein 1 0.023 0.4606 0.6625
Trichomonas vaginalis conserved hypothetical protein 0.0014 0.0025 0.0128
Loa Loa (eye worm) heat shock protein 75 0.0014 0.0009 0.0015
Trypanosoma brucei THT1 - hexose transporter, putative 0.0032 0.0392 0.1539
Echinococcus multilocularis calcium:calmodulin dependent protein kinase type 0.0032 0.0393 0.0554
Echinococcus granulosus GTP binding nuclear protein Ran 0.0021 0.0162 0.022
Toxoplasma gondii non-specific serine/threonine protein kinase 0.0022 0.0193 0.0315
Mycobacterium ulcerans aldehyde dehydrogenase 0.0062 0.1035 0.7744
Schistosoma mansoni lysyl-tRNA synthetase 0.0023 0.0204 0.0281
Schistosoma mansoni cathepsin F (C01 family) 0.0034 0.045 0.0635
Echinococcus granulosus endoplasmin 0.0026 0.0281 0.0392
Brugia malayi cathepsin L-like precursor 0.0023 0.0209 0.0415
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0131 0.2498 1
Echinococcus multilocularis solute carrier family 2 facilitated glucose 0.0102 0.1886 0.2704
Trichomonas vaginalis Clan CA, family C1, papain-like cysteine peptidase 0.0034 0.045 0.2292
Echinococcus granulosus mothers against decapentaplegic 5 0.0016 0.0068 0.0085
Schistosoma mansoni hypothetical protein 0.0112 0.2099 0.3012
Loa Loa (eye worm) sugar transporter 0.0014 0.0025 0.0041
Trichomonas vaginalis PIKK family atypical protein kinase 0.002 0.0145 0.0737
Brugia malayi Cathepsin L-like precursor 0.0034 0.045 0.0916
Plasmodium falciparum mitogen-activated protein kinase 2 0.0165 0.3229 0.3613
Onchocerca volvulus 0.0014 0.0025 0.0122
Trypanosoma cruzi major cysteine proteinase, putative 0.0103 0.1904 0.762
Trichomonas vaginalis PIKK family atypical protein kinase 0.0057 0.0931 0.4745
Trichomonas vaginalis D-aminoacylase, putative 0.0076 0.133 0.6777
Mycobacterium tuberculosis Conserved protein 0.0076 0.133 0.1308
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0034 0.045 0.2292
Plasmodium vivax glutathione reductase, putative 0.0046 0.0698 0.0773
Leishmania major glucose transporter/membrane transporter D2, putative 0.0032 0.0392 0.1539
Mycobacterium tuberculosis Possible cytochrome P450 126 Cyp126 0.0015 0.0031 0.0006
Toxoplasma gondii transporter, major facilitator family protein 0.0014 0.0025 0.0028
Leishmania major cytochrome p450-like protein 0.0015 0.0031 0.0087
Echinococcus granulosus smad 0.0016 0.0068 0.0085
Entamoeba histolytica hypothetical protein 0.0112 0.2099 1
Schistosoma mansoni serine/threonine protein kinase 0.0052 0.0815 0.1161
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0018 0.0096 0.049
Echinococcus granulosus thioredoxin glutathione reductase 0.0046 0.0698 0.0992
Brugia malayi beta-lactamase 0.0076 0.133 0.2746
Schistosoma mansoni hypothetical protein 0.0032 0.0391 0.055
Entamoeba histolytica protein kinase rad3, putative 0.002 0.0145 0.0649
Giardia lamblia Grp94/Hsp90 0.0026 0.0281 0.1322
Trypanosoma brucei glucose transporter, putative 0.0032 0.0392 0.1539
Loa Loa (eye worm) hypothetical protein 0.0032 0.0391 0.0638
Plasmodium falciparum thioredoxin reductase 0.0016 0.0059 0.0056
Leishmania major trypanothione reductase 0.0046 0.0698 0.2767
Trypanosoma cruzi phosphatidylinositol kinase related protein, putative 0.002 0.0145 0.0579
Trichomonas vaginalis sugar transporter, putative 0.0014 0.0025 0.0128
Trichomonas vaginalis sugar transport protein, putative 0.0014 0.0025 0.0128
Brugia malayi cytochrome P450 0.0015 0.0031 0.0045
Loa Loa (eye worm) beta-LACTamase domain containing family member 0.0076 0.133 0.2172
Schistosoma mansoni transcription factor LCR-F1 0.0112 0.2099 0.3012
Echinococcus granulosus mitogen activated protein kinase 3 0.0052 0.0815 0.1161
Trichomonas vaginalis conserved hypothetical protein 0.0032 0.0392 0.1999
Giardia lamblia Endonuclease/Exonuclease/phosphatase 0.0019 0.0128 0.0531
Echinococcus granulosus solute carrier family 22 0.0014 0.0025 0.0023
Leishmania major cathepsin L-like protease 0.0131 0.2498 1
Onchocerca volvulus 0.0023 0.0209 0.1512
Mycobacterium ulcerans cytochrome P450 136A2 Cyp136A2 0.0015 0.0031 0.0042
Trypanosoma cruzi cysteine protease, putative 0.0018 0.0096 0.0385
Loa Loa (eye worm) MH2 domain-containing protein 0.0016 0.0068 0.0111
Entamoeba histolytica cysteine proteinase, putative 0.0034 0.045 0.2108
Brugia malayi RNA, U transporter 1 0.008 0.1426 0.2946
Toxoplasma gondii sugar transporter ST1 0.0014 0.0025 0.0028
Echinococcus granulosus calcium:calmodulin dependent protein kinase type 0.0032 0.0393 0.0554
Trypanosoma cruzi glucose transporter, putative 0.0014 0.0025 0.0101
Trichomonas vaginalis PIKK family atypical protein kinase 0.0079 0.1388 0.7073
Trichomonas vaginalis Clan CA, family C1, papain-like cysteine peptidase 0.0034 0.045 0.2292
Entamoeba histolytica protein kinase, putative 0.0032 0.0393 0.1838
Trypanosoma brucei Phosphatidylinositol 3-kinase tor1 0.0106 0.1962 0.7846
Trichomonas vaginalis PIKK family atypical protein kinase 0.0084 0.1503 0.7663
Trypanosoma cruzi dihydrolipoamide dehydrogenase, putative 0.0016 0.0059 0.0237
Giardia lamblia Kinase, CMGC MAPK 0.0052 0.0815 0.4078
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0131 0.2498 1
Echinococcus multilocularis Peptidase C19, ubiquitin carboxyl terminal hydrolase 2 0.0074 0.1291 0.1848
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0034 0.045 0.2292
Echinococcus multilocularis mitogen activated protein kinase 3 0.0052 0.0815 0.1161
Trichomonas vaginalis PIKK family atypical protein kinase 0.0035 0.0472 0.2407
Schistosoma mansoni hypothetical protein 0.0015 0.0048 0.0057
Trypanosoma brucei heat shock protein, putative 0.0033 0.0424 0.1669
Mycobacterium ulcerans cytochrome P450 105Q4 Cyp105Q4 0.0015 0.0031 0.0042
Mycobacterium tuberculosis Probable membrane NADH dehydrogenase NdhA 0.0105 0.1949 0.1929
Schistosoma mansoni protein kinase 0.0032 0.0393 0.0554
Echinococcus multilocularis survival motor neuron protein 1 0.023 0.4606 0.6625
Mycobacterium ulcerans cytochrome p450 150 cyp150 0.0015 0.0031 0.0042
Plasmodium falciparum cysteine proteinase falcipain 1 0.0018 0.0096 0.0098
Brugia malayi Intermediate filament tail domain containing protein 0.0026 0.0282 0.0568
Mycobacterium tuberculosis Probable esterase LipL 0.0076 0.133 0.1308
Loa Loa (eye worm) cytochrome P450 family protein 0.0032 0.0408 0.0666
Schistosoma mansoni ubiquitin-specific peptidase 2 (C19 family) 0.0074 0.1291 0.1848
Plasmodium falciparum calcium-dependent protein kinase 1 0.0032 0.0394 0.0432
Plasmodium falciparum dihydrolipoyl dehydrogenase, mitochondrial 0.0016 0.0059 0.0056
Brugia malayi Thioredoxin reductase 0.0046 0.0698 0.1432
Loa Loa (eye worm) pigment dispersing factor receptor c 0.01 0.1838 0.3002
Leishmania major ubiquitin hydrolase, putative,cysteine peptidase, Clan CA, family C19, putative 0.0074 0.1291 0.5151
Mycobacterium ulcerans lysyl-tRNA synthetase 0.0023 0.0204 0.1371
Plasmodium vivax calcium-dependent protein kinase, putative 0.0032 0.0394 0.0432
Plasmodium vivax sugar transporter, putative 0.0014 0.0025 0.0018
Giardia lamblia Prolyl-tRNA synthetase 0.0031 0.037 0.1782
Trichomonas vaginalis PIKK family atypical protein kinase 0.0062 0.1047 0.5335
Mycobacterium tuberculosis Conserved protein 0.0076 0.133 0.1308
Leishmania major mitogen activated protein kinase 4, putative;with=GeneDB:LmxM19.1440 0.0052 0.0815 0.3237
Echinococcus multilocularis cathepsin l cysteine peptidase 0.0034 0.045 0.0635
Onchocerca volvulus 0.0076 0.133 1
Brugia malayi Iron-sulfur cluster assembly accessory protein 0.0047 0.0717 0.1472
Leishmania major target of rapamycin (TOR) kinase 1, putative 0.0106 0.1962 0.7846
Echinococcus multilocularis solute carrier family 22 0.0014 0.0025 0.0023
Entamoeba histolytica cysteine proteinase, putative 0.0018 0.0096 0.0417
Echinococcus multilocularis aldehyde dehydrogenase, mitochondrial 0.0062 0.1035 0.1479
Entamoeba histolytica cysteine protease, putative 0.0018 0.0096 0.0417
Echinococcus multilocularis mitogen activated protein kinase 0.0052 0.0815 0.1161
Mycobacterium ulcerans cytochrome P450 51B1 Cyp51B1 0.0015 0.0031 0.0042
Loa Loa (eye worm) hypothetical protein 0.0034 0.045 0.0735
Brugia malayi Endoplasmin precursor 0.0033 0.0424 0.0864
Trichomonas vaginalis importin beta-1, putative 0.0023 0.0207 0.1055
Brugia malayi Cathepsin L-like precursor 0.0023 0.0209 0.0415
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0034 0.045 0.2292
Brugia malayi MH2 domain containing protein 0.0016 0.0068 0.0123
Echinococcus multilocularis calcium dependent protein kinase 0.0029 0.0343 0.0481
Brugia malayi Papain family cysteine protease containing protein 0.0034 0.045 0.0916
Loa Loa (eye worm) major facilitator superfamily transporter 0.0014 0.0025 0.0041
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0023 0.0209 0.1064
Toxoplasma gondii FATC domain-containing protein 0.002 0.0145 0.0232
Loa Loa (eye worm) hypothetical protein 0.0014 0.0025 0.0041
Plasmodium falciparum glutathione reductase 0.0016 0.0059 0.0056
Mycobacterium tuberculosis Probable cytochrome P450 123 Cyp123 0.0015 0.0031 0.0006
Brugia malayi major facilitator superfamily protein 0.0014 0.0025 0.0033
Trypanosoma cruzi phosphatidylinositol 3-related kinase, putative 0.0035 0.0472 0.1891
Trypanosoma cruzi dihydrolipoyl dehydrogenase, putative 0.0016 0.0059 0.0237
Echinococcus granulosus guanine nucleotide binding protein Gs subunit 0.0089 0.1618 0.2319
Brugia malayi Cytochrome P450 family protein 0.0032 0.0408 0.0829
Mycobacterium ulcerans flavoprotein disulfide reductase 0.0016 0.0059 0.0262
Loa Loa (eye worm) hypothetical protein 0.0076 0.133 0.2172
Plasmodium falciparum calcium-dependent protein kinase 4 0.0032 0.0394 0.0432
Leishmania major heat shock protein 83-1 0.0033 0.0424 0.1669
Plasmodium falciparum calcium-dependent protein kinase 3 0.0032 0.0394 0.0432
Schistosoma mansoni ran 0.0021 0.0162 0.022
Echinococcus granulosus TGF beta signal transducer SmadC 0.0016 0.0068 0.0085
Trypanosoma cruzi hypothetical protein, conserved 0.0076 0.133 0.5323
Trichomonas vaginalis mercuric reductase, putative 0.0016 0.0059 0.0302
Schistosoma mansoni endoplasmin 0.0033 0.0424 0.0599
Trichomonas vaginalis PIKK family atypical protein kinase 0.0079 0.1388 0.7073
Loa Loa (eye worm) cytochrome P450 family protein 0.0032 0.0408 0.0666
Trichomonas vaginalis PIKK family atypical protein kinase 0.0106 0.1962 1
Trichomonas vaginalis Clan CA, family C19, ubiquitin hydrolase-like cysteine peptidase 0.0074 0.1291 0.6581
Trichomonas vaginalis PIKK family atypical protein kinase 0.0057 0.0931 0.4745
Mycobacterium ulcerans cytochrome P450 188A3 Cyp188A3 0.0015 0.0031 0.0042
Plasmodium vivax calcium-dependent protein kinase 3, putative 0.0032 0.0394 0.0432
Toxoplasma gondii heat shock protein HSP90 0.0033 0.0424 0.0711
Trypanosoma cruzi hexose transporter, putative 0.0032 0.0392 0.157
Brugia malayi Papain family cysteine protease containing protein 0.0018 0.0096 0.0181
Schistosoma mansoni intermediate filament proteins 0.0026 0.0282 0.0393
Plasmodium vivax vivapain-1 0.0018 0.0096 0.0098
Brugia malayi beta-lactamase family protein 0.0076 0.133 0.2746
Mycobacterium tuberculosis Probable cytochrome P450 137 Cyp137 0.0015 0.0031 0.0006
Trypanosoma cruzi cytochrome p450-like protein, putative 0.0015 0.0031 0.0123
Trypanosoma cruzi mitogen activated protein kinase 2, putative 0.0052 0.0815 0.3262
Trichomonas vaginalis PIKK family atypical protein kinase 0.0063 0.106 0.5402
Loa Loa (eye worm) cytochrome P450 0.0015 0.0031 0.005
Trypanosoma brucei glucose transporter, putative 0.0032 0.0392 0.1539
Mycobacterium tuberculosis Probable reductase 0.0105 0.1949 0.1929
Trypanosoma brucei calcium/calmodulin-dependent protein kinase, putative 0.0032 0.0393 0.1543
Echinococcus multilocularis heat shock protein 90 0.0033 0.0424 0.0599
Onchocerca volvulus 0.0026 0.0282 0.2067
Trichomonas vaginalis sugar transporter, putative 0.0032 0.0392 0.1999
Leishmania major target of rapamycin (TOR) kinase 2, putative 0.0106 0.1962 0.7846
Entamoeba histolytica hypothetical protein 0.0112 0.2099 1
Mycobacterium tuberculosis Dihydrolipoamide dehydrogenase LpdC (lipoamide reductase (NADH)) (lipoyl dehydrogenase) (dihydrolipoyl dehydrogenase) (diaphoras 0.0117 0.2198 0.2178
Leishmania major glucose transporter, lmgt2 0.0032 0.0392 0.1539
Loa Loa (eye worm) nucleolar RNA-associated protein alpha 0.0302 0.6122 1
Plasmodium vivax CDK-related protein kinase 6, putative 0.0434 0.8919 1
Echinococcus granulosus cathepsin L 0.0018 0.0096 0.0126
Mycobacterium leprae DIHYDROLIPOAMIDE DEHYDROGENASE LPD (LIPOAMIDE REDUCTASE (NADH)) (LIPOYL DEHYDROGENASE) (DIHYDROLIPOYL DEHYDROGENASE) (DIAPHORASE 0.0117 0.2198 1
Echinococcus multilocularis cysteine protease 0.0034 0.045 0.0635
Trypanosoma cruzi ubiquitin carboxyl-terminal hydrolase, putative 0.0074 0.1291 0.5168
Mycobacterium tuberculosis Probable cytochrome P450 monooxygenase 142 Cyp142 0.0015 0.0031 0.0006
Onchocerca volvulus 0.0014 0.0025 0.0122
Trypanosoma brucei dihydrolipoyl dehydrogenase 0.0016 0.0059 0.0202
Echinococcus multilocularis synaptic vesicle 2 protein 0.0014 0.0025 0.0023
Trichomonas vaginalis sugar transporter, putative 0.0014 0.0025 0.0128
Schistosoma mansoni smad1 5 8 and 0.0016 0.0068 0.0085
Trypanosoma cruzi cruzipain precursor, putative 0.0131 0.2498 1
Trichomonas vaginalis Clan CA, family C19, ubiquitin hydrolase-like cysteine peptidase 0.0074 0.1291 0.6581
Onchocerca volvulus 0.0047 0.0717 0.5363
Trichomonas vaginalis sugar transporter, putative 0.0014 0.0025 0.0128
Echinococcus granulosus cysteine protease 0.0018 0.0096 0.0126
Toxoplasma gondii thioredoxin reductase 0.0046 0.0698 0.1179
Leishmania major cathepsin L-like protease 0.0034 0.045 0.177
Onchocerca volvulus 0.0014 0.0025 0.0122
Trichomonas vaginalis lysyl-tRNA synthetase, putative 0.002 0.0144 0.0736
Schistosoma mansoni family S12 unassigned peptidase (S12 family) 0.0076 0.133 0.1903
Mycobacterium ulcerans cytochrome P450 123A3 Cyp123A3 0.0015 0.0031 0.0042
Onchocerca volvulus 0.0014 0.0025 0.0122
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0034 0.045 0.2292
Trypanosoma brucei glucose transporter, putative 0.0032 0.0392 0.1539
Trichomonas vaginalis PIKK family atypical protein kinase 0.0028 0.0322 0.1641
Trichomonas vaginalis sugar transporter, putative 0.0014 0.0025 0.0128
Trichomonas vaginalis sugar transporter, putative 0.0014 0.0025 0.0128
Entamoeba histolytica cysteine proteinase, putative 0.0018 0.0096 0.0417
Schistosoma mansoni hypothetical protein 0.0032 0.0391 0.055
Echinococcus granulosus guanine nucleotide binding protein Gs subunit 0.0089 0.1618 0.2319
Giardia lamblia GTOR 0.0106 0.1962 1
Trypanosoma brucei phosphatidylinositol kinase related protein, putative 0.002 0.0145 0.0545
Echinococcus granulosus DNA apurinic or apyrimidinic site lyase 0.0019 0.0128 0.0171
Schistosoma mansoni lysyl-tRNA synthetase 0.0023 0.0204 0.0281
Loa Loa (eye worm) cysteine protease 0.0034 0.045 0.0735
Schistosoma mansoni lamin 0.0026 0.0282 0.0393
Trichomonas vaginalis sugar transporter, putative 0.0014 0.0025 0.0128
Schistosoma mansoni glucose transport protein 0.0102 0.1886 0.2704
Trypanosoma cruzi Phosphatidylinositol 3-kinase tor2 0.0106 0.1962 0.7854
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0034 0.045 0.2292
Toxoplasma gondii cell-cycle-associated protein kinase MAPK, putative 0.0165 0.3229 0.5515
Trypanosoma cruzi mitogen-activated protein kinase 11, putative 0.0052 0.0815 0.3262
Onchocerca volvulus 0.0034 0.045 0.3337
Brugia malayi calcium-independent alpha-latrotoxin receptor 2, putative 0.0032 0.0391 0.0793
Echinococcus granulosus beta LACTamase domain containing family member 0.0076 0.133 0.1903
Onchocerca volvulus 0.0014 0.0025 0.0122
Loa Loa (eye worm) hypothetical protein 0.0014 0.0025 0.0041
Leishmania major cathepsin L-like protease 0.0131 0.2498 1
Trichomonas vaginalis sugar transporter, putative 0.0014 0.0025 0.0128
Trichomonas vaginalis glucose transporter, putative 0.0032 0.0392 0.1999
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0034 0.045 0.2292
Trypanosoma brucei phosphatidylinositol 4-kinase, putative 0.0106 0.1962 0.7846
Schistosoma mansoni cytochrome P450 0.0015 0.0031 0.0031
Leishmania major cathepsin L-like protease 0.0131 0.2498 1
Echinococcus granulosus General substrate transporter 0.0088 0.1581 0.2266
Echinococcus granulosus calcium:calmodulin dependent protein kinase type 0.0032 0.0393 0.0554
Trypanosoma brucei lysyl-tRNA synthetase, putative 0.0023 0.0204 0.0783
Wolbachia endosymbiont of Brugia malayi exonuclease III 0.0019 0.0128 0.4014
Echinococcus granulosus lamin dm0 0.0026 0.0282 0.0393
Echinococcus granulosus solute carrier family 2 facilitated glucose 0.0102 0.1886 0.2704
Entamoeba histolytica Phosphatidylinositol 3- and 4-kinase family 0.002 0.0145 0.0649
Trypanosoma brucei dihydrolipoamide dehydrogenase 0.0016 0.0059 0.0202
Mycobacterium ulcerans cytochrome P450 125A7 Cyp125A7 0.0015 0.0031 0.0042
Entamoeba histolytica cysteine protease, putative 0.0018 0.0096 0.0417
Toxoplasma gondii facilitative glucose transporter GT1 0.0102 0.1886 0.3215
Leishmania major heat shock protein 83-1 0.0033 0.0424 0.1669
Plasmodium falciparum GTP-binding nuclear protein RAN/TC4 0.0021 0.0162 0.0172
Entamoeba histolytica cysteine protease, putative 0.0018 0.0096 0.0417
Trypanosoma brucei THT1 - hexose transporter, putative 0.0032 0.0392 0.1539
Trichomonas vaginalis sugar transporter, putative 0.0014 0.0025 0.0128
Schistosoma mansoni hypothetical protein 0.0032 0.0391 0.055
Leishmania major cathepsin L-like protease 0.0034 0.045 0.177
Brugia malayi Cathepsin L-like precursor 0.0034 0.045 0.0916
Toxoplasma gondii GTP-binding nuclear protein ran/tc4 0.0021 0.0162 0.0262
Mycobacterium tuberculosis Cytochrome P450 121 Cyp121 0.0015 0.0031 0.0006
Echinococcus multilocularis snurportin 1 0.0302 0.6122 0.8809
Plasmodium falciparum endoplasmin, putative 0.002 0.0152 0.0161
Mycobacterium tuberculosis Probable oxidoreductase 0.0117 0.2198 0.2178
Echinococcus granulosus serine:threonine protein kinase SMG1 0.002 0.0145 0.0195
Onchocerca volvulus 0.0014 0.0025 0.0122
Trypanosoma cruzi dihydrolipoamide dehydrogenase, putative 0.0016 0.0059 0.0237
Echinococcus granulosus mitogen activated protein kinase 0.0052 0.0815 0.1161
Mycobacterium leprae Probable lysyl-tRNA synthase LysS (lysine--tRNA ligase 1) (LysRS 1) (lysine translase) 0.0019 0.0131 0.0464
Mycobacterium leprae Possible lysyl-tRNA synthetase 2 LysX 0.0023 0.0204 0.08
Schistosoma mansoni heat shock protein 0.0033 0.0424 0.0599
Trichomonas vaginalis CMGC family protein kinase 0.0052 0.0815 0.4153
Trichomonas vaginalis sugar transporter, putative 0.0014 0.0025 0.0128
Brugia malayi glutathione reductase 0.0046 0.0698 0.1432
Echinococcus multilocularis DNA (apurinic or apyrimidinic site) lyase 0.0019 0.0128 0.0171
Loa Loa (eye worm) beta-lactamase 0.0076 0.133 0.2172
Echinococcus granulosus dihydrolipoamide dehydrogenase 0.0016 0.0059 0.0072
Trypanosoma cruzi hypothetical protein, conserved 0.0076 0.133 0.5323
Echinococcus granulosus Basic leucine zipper bZIP transcription 0.0112 0.2099 0.3012
Trypanosoma cruzi target of rapamycin kinase 3 0.0084 0.1505 0.6025
Brugia malayi Sugar transporter family protein 0.0014 0.0025 0.0033
Trichomonas vaginalis Clan CA, family C1, cathepsin L or K-like cysteine peptidase 0.0034 0.045 0.2292
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0034 0.045 0.2292
Trypanosoma brucei phosphatidylinositol 3-kinase, putative 0.0035 0.0472 0.1861
Echinococcus granulosus cathepsin l1 0.0023 0.0209 0.0288
Onchocerca volvulus 0.0026 0.0282 0.2067
Echinococcus multilocularis cathepsin L cysteine protease 0.0034 0.045 0.0635
Echinococcus multilocularis PIK kinase, FAT and Armadillo domain containing protein 0.0015 0.0048 0.0057
Brugia malayi Papain family cysteine protease containing protein 0.0018 0.0096 0.0181
Trichomonas vaginalis sugar transporter, putative 0.0014 0.0025 0.0128
Loa Loa (eye worm) hypothetical protein 0.0014 0.0025 0.0041
Schistosoma mansoni Smad4 0.0016 0.0068 0.0085
Mycobacterium tuberculosis Probable NADH dehydrogenase Ndh 0.0105 0.1949 0.1929
Trypanosoma cruzi cysteine proteinase, putative 0.0018 0.0096 0.0385
Trichomonas vaginalis heat shock protein, putative 0.002 0.0152 0.0777
Trypanosoma cruzi prolyl-tRNA synthetase, putative 0.0036 0.0478 0.1913
Plasmodium falciparum cysteine proteinase falcipain 2b 0.0034 0.045 0.0495
Giardia lamblia Lysyl-tRNA synthetase 0.0023 0.0204 0.0923
Loa Loa (eye worm) hypothetical protein 0.023 0.4606 0.7525
Trichomonas vaginalis Clan CA, family C1, papain-like cysteine peptidase 0.0034 0.045 0.2292
Schistosoma mansoni family S12 unassigned peptidase (S12 family) 0.0076 0.133 0.1903
Brugia malayi Bifunctional aminoacyl-tRNA synthetase 0.0031 0.037 0.0751
Loa Loa (eye worm) MH1 domain-containing protein 0.0016 0.0068 0.0111
Trypanosoma cruzi mitogen activated protein kinase 4, putative 0.0052 0.0815 0.3262
Trypanosoma brucei glucose transporter, putative 0.0032 0.0392 0.1539
Onchocerca volvulus 0.0034 0.045 0.3337
Schistosoma mansoni aldehyde dehydrogenase 0.0062 0.1035 0.1479
Mycobacterium tuberculosis Probable cytochrome P450 124 Cyp124 0.0015 0.0031 0.0006
Trichomonas vaginalis PIKK family atypical protein kinase 0.0057 0.0929 0.4735
Trypanosoma brucei cytochrome P450, putative 0.0032 0.0408 0.1602
Mycobacterium tuberculosis Probable cytochrome P450 136 Cyp136 0.0015 0.0031 0.0006
Plasmodium vivax vivapain-2 0.0034 0.045 0.0495
Mycobacterium leprae Probable lipase LipE 0.0076 0.133 0.5994
Trichomonas vaginalis sugar transporter, putative 0.0014 0.0025 0.0128
Echinococcus multilocularis 0.0015 0.0031 0.0031
Loa Loa (eye worm) hypothetical protein 0.0014 0.0025 0.0041
Entamoeba histolytica cysteine proteinase, putative 0.0018 0.0096 0.0417
Trichomonas vaginalis penicillin-binding protein, putative 0.0076 0.133 0.6777
Entamoeba histolytica exodeoxyribonuclease III, putative 0.0019 0.0128 0.0569
Echinococcus granulosus cadherin EGF LAG seven pass G type receptor 0.0032 0.0391 0.055
Leishmania major protein kinase, putative 0.0032 0.0393 0.1543
Trichomonas vaginalis sugar transporter, putative 0.0014 0.0025 0.0128
Mycobacterium ulcerans cytochrome P450 108B4 Cyp108B4 0.0015 0.0031 0.0042
Echinococcus granulosus cathepsin l cysteine peptidase 0.0034 0.045 0.0635
Trichomonas vaginalis CMGC family protein kinase 0.0052 0.0815 0.4153
Loa Loa (eye worm) hypothetical protein 0.0022 0.0177 0.029
Trichomonas vaginalis CMGC family protein kinase 0.0052 0.0815 0.4153
Plasmodium falciparum cysteine proteinase falcipain 2a 0.0034 0.045 0.0495
Loa Loa (eye worm) glutathione reductase 0.0046 0.0698 0.114
Echinococcus granulosus calcium:calmodulin dependent protein kinase type 0.0032 0.0393 0.0554
Toxoplasma gondii cytochrome p450 superfamily protein 0.0015 0.0031 0.0037
Trichomonas vaginalis Importin beta-1 subunit, putative 0.0023 0.0207 0.1055
Leishmania major hypothetical protein, conserved 0.0014 0.0025 0.0065
Onchocerca volvulus 0.0014 0.0025 0.0122
Toxoplasma gondii target of rapamycin (TOR), putative 0.0079 0.1388 0.2361
Echinococcus multilocularis cadherin EGF LAG seven pass G type receptor 0.0032 0.0391 0.055
Brugia malayi MH1 domain containing protein 0.0016 0.0068 0.0123
Trichomonas vaginalis sugar transporter, putative 0.0014 0.0025 0.0128
Trypanosoma cruzi heat shock protein 90, putative 0.0033 0.0424 0.1699
Trichomonas vaginalis PIKK family atypical protein kinase 0.0057 0.0931 0.4745
Plasmodium falciparum protein kinase 7 0.0289 0.5847 0.6552
Trypanosoma cruzi phosphatidylinositol 3-related kinase, putative 0.0035 0.0472 0.1891
Mycobacterium tuberculosis Conserved protein 0.0076 0.133 0.1308
Wolbachia endosymbiont of Brugia malayi dihydrolipoamide dehydrogenase E3 component 0.0016 0.0059 0.1333
Trypanosoma brucei glucose transporter 1E 0.0032 0.0392 0.1539
Plasmodium falciparum protein kinase 6 0.0434 0.8919 1
Leishmania major heat shock protein 83-1 0.0033 0.0424 0.1669
Loa Loa (eye worm) D-ets-4 DNA binding domain-containing protein 0.0074 0.1286 0.21
Plasmodium vivax mitogen-activated protein kinase 2, putative 0.0165 0.3229 0.3613
Trichomonas vaginalis Importin beta-1 subunit, putative 0.0023 0.0207 0.1055
Trichomonas vaginalis endoplasmin, putative 0.002 0.0152 0.0777
Brugia malayi Phosphatidylinositol 3- and 4-kinase family protein 0.0106 0.1962 0.406
Loa Loa (eye worm) hypothetical protein 0.0014 0.0025 0.0041
Loa Loa (eye worm) hypothetical protein 0.0023 0.0204 0.0333
Trichomonas vaginalis sugar transporter, putative 0.0032 0.0392 0.1999
Schistosoma mansoni aldehyde dehydrogenase 0.0062 0.1035 0.1479
Trypanosoma brucei myo-inositol/proton symporter (MIT) 0.0014 0.0025 0.0065
Brugia malayi beta-lactamase family protein 0.0076 0.133 0.2746
Trichomonas vaginalis conserved hypothetical protein 0.0015 0.0048 0.0247
Loa Loa (eye worm) hypothetical protein 0.0015 0.0048 0.0079
Trichomonas vaginalis penicillin-binding protein, putative 0.0076 0.133 0.6777
Giardia lamblia GTP-binding nuclear protein RAN/TC4 0.0021 0.0162 0.0707
Mycobacterium tuberculosis NAD(P)H quinone reductase LpdA 0.0117 0.2198 0.2178
Trichomonas vaginalis sugar transporter, putative 0.0014 0.0025 0.0128
Brugia malayi Ubiquitin carboxyl-terminal hydrolase family protein 0.0074 0.1291 0.2666
Plasmodium falciparum lysine--tRNA ligase 0.0023 0.0204 0.0219
Onchocerca volvulus 0.0034 0.045 0.3337
Mycobacterium ulcerans cytochrome P450 143A3 Cyp143A3 0.0015 0.0031 0.0042
Brugia malayi Ets-domain containing protein 0.0074 0.1286 0.2655
Mycobacterium ulcerans esterase/lipase LipP 0.0076 0.133 1
Schistosoma mansoni smad1 5 8 and 0.0016 0.0068 0.0085
Trichomonas vaginalis PIKK family atypical protein kinase 0.0057 0.0929 0.4735
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0034 0.045 0.2292
Trichomonas vaginalis sugar transporter, putative 0.0014 0.0025 0.0128
Brugia malayi Latrophilin receptor protein 2 0.0032 0.0391 0.0793
Trypanosoma brucei heat shock protein, putative 0.0033 0.0424 0.1669
Trichomonas vaginalis esterase, putative 0.0076 0.133 0.6777
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0018 0.0096 0.035
Trypanosoma brucei trypanothione reductase 0.0046 0.0698 0.2767
Brugia malayi GTP-binding nuclear protein RAN/TC4 0.0021 0.0162 0.0318
Echinococcus granulosus synaptic vesicle 2 protein 0.0014 0.0025 0.0023
Loa Loa (eye worm) hypothetical protein 0.0076 0.133 0.2172
Giardia lamblia Ubiquitin carboxyl-terminal hydrolase 4 0.0074 0.1291 0.6536
Echinococcus granulosus lysyl tRNA synthetase 0.0023 0.0204 0.0281
Onchocerca volvulus 0.0034 0.045 0.3337
Trypanosoma cruzi apurinic/apyrimidinic endonuclease, putative 0.0019 0.0128 0.0512
Toxoplasma gondii aldehyde dehydrogenase 0.0062 0.1035 0.1758
Echinococcus multilocularis serine protein kinase ATM 0.002 0.0145 0.0195
Trypanosoma cruzi cytochrome P450, putative 0.0032 0.0408 0.1633
Loa Loa (eye worm) hypothetical protein 0.0023 0.0209 0.0341
Mycobacterium ulcerans cytochrome P450 124A1, Cyp124A1 0.0015 0.0031 0.0042
Mycobacterium tuberculosis Possible cytochrome P450 135B1 Cyp135B1 0.0015 0.0031 0.0006
Plasmodium vivax heat shock protein 86, putative 0.0033 0.0424 0.0466
Schistosoma mansoni heat shock protein 0.0033 0.0424 0.0599
Plasmodium vivax dihydrolipoyl dehydrogenase, apicoplast, putative 0.0016 0.0059 0.0056
Trypanosoma cruzi dihydrolipoamide dehydrogenase, putative 0.0016 0.0059 0.0237
Trichomonas vaginalis sugar transporter, putative 0.0014 0.0025 0.0128
Mycobacterium ulcerans aldehyde dehydrogenase 0.0062 0.1035 0.7744
Brugia malayi Sugar transporter family protein 0.0102 0.1886 0.3902
Plasmodium vivax unspecified product 0.0018 0.0096 0.0098
Trichomonas vaginalis PIKK family atypical protein kinase 0.002 0.0145 0.0737
Schistosoma mansoni SmCL2-like peptidase (C01 family) 0.0018 0.0096 0.0126
Loa Loa (eye worm) hypothetical protein 0.0025 0.0248 0.0406
Echinococcus multilocularis solute carrier family 2, facilitated glucose 0.0102 0.1886 0.2704
Trypanosoma cruzi dihydrolipoamide dehydrogenase, putative 0.0016 0.0059 0.0237
Plasmodium vivax hypothetical protein, conserved 0.0076 0.133 0.1482
Echinococcus multilocularis lamin dm0 0.0026 0.0282 0.0393
Leishmania major phosphatidylinositol 3-related kinase, putative 0.0035 0.0472 0.1861
Loa Loa (eye worm) hypothetical protein 0.0018 0.0098 0.016
Trichomonas vaginalis conserved hypothetical protein 0.0014 0.0025 0.0128
Trichomonas vaginalis prolyl-tRNA synthetase, putative 0.0031 0.037 0.1887
Mycobacterium tuberculosis Probable chaperone protein HtpG (heat shock protein) (HSP90 family protein) (high temperature protein G) 0.0026 0.0281 0.0257
Trichomonas vaginalis ap endonuclease, putative 0.0019 0.0128 0.0652
Brugia malayi dihydrolipoyl dehydrogenase, mitochondrial precursor, putative 0.0016 0.0059 0.0104
Mycobacterium tuberculosis Probable nitrite reductase [NAD(P)H] large subunit [FAD flavoprotein] NirB 0.0105 0.1949 0.1929
Trichomonas vaginalis conserved hypothetical protein 0.0032 0.0392 0.1999
Loa Loa (eye worm) Papain cysteine protease/cathepsin propeptide inhibitor-containing protein 0.0034 0.045 0.0735
Trichomonas vaginalis sugar transporter, putative 0.0014 0.0025 0.0128
Mycobacterium tuberculosis Probable cytochrome P450 139 Cyp139 0.0015 0.0031 0.0006
Leishmania major importin beta-1 subunit, putative 0.0023 0.0207 0.0795
Plasmodium falciparum AP endonuclease (DNA-[apurinic or apyrimidinic site] lyase), putative 0.0019 0.0128 0.0133
Mycobacterium ulcerans exodeoxyribonuclease III protein XthA 0.0019 0.0128 0.0788
Entamoeba histolytica heat shock protein 90, putative 0.0033 0.0424 0.1988
Loa Loa (eye worm) intermediate filament protein 0.0026 0.0282 0.0461
Plasmodium vivax calcium-dependent protein kinase 1, putative 0.0032 0.0394 0.0432
Loa Loa (eye worm) hypothetical protein 0.0014 0.0025 0.0041
Trichomonas vaginalis myo-inositol transporter, putative 0.0014 0.0025 0.0128
Trichomonas vaginalis conserved hypothetical protein 0.0014 0.0025 0.0128
Toxoplasma gondii calcium-dependent protein kinase CDPK2B 0.0032 0.0394 0.0659
Mycobacterium ulcerans beta-lactamase 0.0076 0.133 1
Schistosoma mansoni ap endonuclease 0.0019 0.0128 0.0171
Trypanosoma cruzi hexose transporter 0.0032 0.0392 0.157
Trichomonas vaginalis ran, putative 0.0021 0.0162 0.0826
Echinococcus granulosus GPCR family 2 0.0032 0.0391 0.055
Giardia lamblia NADH oxidase lateral transfer candidate 0.0016 0.0059 0.0176
Trichomonas vaginalis conserved hypothetical protein 0.0102 0.1886 0.9612
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0034 0.045 0.2292
Mycobacterium tuberculosis Lysyl-tRNA synthetase 1 LysS (lysine--tRNA ligase 1) (LysRS 1) (lysine translase) 0.0019 0.0131 0.0106
Loa Loa (eye worm) papain family cysteine protease containing protein 0.0034 0.045 0.0735
Trichomonas vaginalis conserved hypothetical protein 0.0074 0.1291 0.6581
Entamoeba histolytica cysteine protease, putative 0.0018 0.0096 0.0417
Echinococcus granulosus solute carrier family 2 facilitated glucose 0.0102 0.1886 0.2704
Loa Loa (eye worm) phosphatidylinositol 3 0.0035 0.0472 0.0772
Schistosoma mansoni hypothetical protein 0.0341 0.6948 1
Mycobacterium tuberculosis Probable cytochrome P450 140 Cyp140 0.0015 0.0031 0.0006
Toxoplasma gondii sugar transporter ST2 0.0014 0.0025 0.0028
Echinococcus granulosus snurportin 1 0.0302 0.6122 0.8809
Trypanosoma cruzi Lanosterol 14-alpha demethylase 0.0015 0.0031 0.0123
Echinococcus multilocularis lysyl tRNA synthetase 0.0023 0.0204 0.0281
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0018 0.0096 0.049
Trypanosoma brucei hypothetical protein, conserved 0.0076 0.133 0.5306
Trichomonas vaginalis PIKK family atypical protein kinase 0.0071 0.1224 0.6239
Trypanosoma brucei heat shock protein, putative 0.0033 0.0424 0.1669
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0034 0.045 0.2292
Mycobacterium tuberculosis Probable cytochrome P450 138 Cyp138 0.0015 0.0031 0.0006
Trichomonas vaginalis PIKK family atypical protein kinase 0.0079 0.1388 0.7073
Trypanosoma brucei heat shock protein, putative 0.0033 0.0424 0.1669
Brugia malayi Phosphatidylinositol 3- and 4-kinase family protein 0.0035 0.0472 0.0963
Trypanosoma brucei importin beta-1 subunit, putative 0.0028 0.032 0.1251
Echinococcus multilocularis musashi 0.0026 0.0282 0.0393
Leishmania major cathepsin L-like protease 0.0034 0.045 0.177
Echinococcus granulosus GA binding protein alpha chain 0.0074 0.1286 0.184
Onchocerca volvulus 0.0034 0.045 0.3337
Toxoplasma gondii cathepsin CPL 0.0034 0.045 0.0755
Loa Loa (eye worm) CYP4Cod1 0.0032 0.0408 0.0666
Trichomonas vaginalis D-aminoacylase, putative 0.0076 0.133 0.6777
Mycobacterium ulcerans cytochrome P450 187A4 Cyp187A4 0.0015 0.0031 0.0042
Entamoeba histolytica cysteine protease, putative 0.0018 0.0096 0.0417
Trypanosoma cruzi heat shock protein, putative 0.0014 0.0009 0.0036
Echinococcus multilocularis beta LACTamase domain containing family member 0.0076 0.133 0.1903
Trypanosoma cruzi cysteine peptidase, putative 0.0034 0.045 0.18
Plasmodium vivax endoplasmin, putative 0.0033 0.0424 0.0466
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0131 0.2498 1
Schistosoma mansoni nuclear transcription factor X-box binding 1 (nfx1) 0.0014 0.0025 0.0023
Plasmodium falciparum thioredoxin reductase 0.0046 0.0698 0.0773
Trichomonas vaginalis heat shock protein, putative 0.0026 0.0281 0.1433
Loa Loa (eye worm) hypothetical protein 0.0014 0.0025 0.0041
Brugia malayi Cathepsin L-like precursor 0.0034 0.045 0.0916
Echinococcus multilocularis GTP binding nuclear protein Ran 0.0021 0.0162 0.022
Plasmodium falciparum calcium-dependent protein kinase 5 0.0032 0.0394 0.0432
Onchocerca volvulus 0.0014 0.0025 0.0122
Trichomonas vaginalis PIKK family atypical protein kinase 0.0084 0.1503 0.7663
Trypanosoma cruzi heat shock protein 85, putative 0.0033 0.0424 0.1699
Brugia malayi intermediate filament protein 0.0026 0.0282 0.0568
Trichomonas vaginalis sugar transporter, putative 0.0014 0.0025 0.0128
Trichomonas vaginalis glucose transporter, putative 0.0014 0.0025 0.0128
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0131 0.2498 1
Trypanosoma cruzi apurinic/apyrimidinic endonuclease 0.0019 0.0128 0.0512
Entamoeba histolytica phosphatidylinositol3-kinaseTor2, putative 0.0106 0.1962 0.9345
Schistosoma mansoni cathepsin F (C01 family) 0.0034 0.045 0.0635
Brugia malayi Phosphatidylinositol 3- and 4-kinase family protein 0.002 0.0145 0.0282
Brugia malayi Cathepsin L-like cysteine proteinase 0.0023 0.0209 0.0415
Entamoeba histolytica Ran family GTPase 0.0021 0.0162 0.0732
Echinococcus multilocularis cathepsin L cysteine protease 0.0034 0.045 0.0635
Schistosoma mansoni SmCL2-like peptidase (C01 family) 0.0018 0.0096 0.0126
Schistosoma mansoni lamin 0.0026 0.0282 0.0393
Brugia malayi Smad1 0.0016 0.0068 0.0123
Mycobacterium leprae PROBABLE NADH DEHYDROGENASE NDH 0.0105 0.1949 0.8853
Mycobacterium tuberculosis Probable exodeoxyribonuclease III protein XthA (exonuclease III) (EXO III) (AP endonuclease VI) 0.0019 0.0128 0.0103
Leishmania major prolyl-tRNA synthetase, putative,bifunctional aminoacyl-tRNA synthetase, putative 0.0036 0.0478 0.1883
Echinococcus multilocularis GPCR, family 2 0.0032 0.0391 0.055
Trypanosoma cruzi hexose transporter, putative 0.0032 0.0392 0.157
Trypanosoma brucei FAT domain/Rapamycin binding domain/Phosphatidylinositol 3- and 4-kinase, putative 0.0044 0.0652 0.2581
Mycobacterium tuberculosis Probable conserved lipoprotein 0.0076 0.133 0.1308
Echinococcus multilocularis calcium:calmodulin dependent protein kinase type 0.0032 0.0393 0.0554
Loa Loa (eye worm) Smad1 0.0016 0.0068 0.0111
Trichomonas vaginalis sugar transporter, putative 0.0014 0.0025 0.0128
Echinococcus granulosus heat shock protein 0.0033 0.0424 0.0599
Trichomonas vaginalis PIKK family atypical protein kinase 0.0106 0.1962 1
Brugia malayi FAT domain containing protein 0.0015 0.0048 0.0082
Plasmodium vivax importin-beta 2, putative 0.0028 0.032 0.0349
Trypanosoma brucei phosphatidylinositol 3-kinase tor, putative 0.005 0.0781 0.31
Trypanosoma cruzi lysyl-tRNA synthetase, putative 0.0023 0.0204 0.0816
Loa Loa (eye worm) hypothetical protein 0.0076 0.133 0.2172
Brugia malayi hypothetical protein 0.0112 0.2099 0.4345
Mycobacterium tuberculosis Cytochrome P450 51 Cyp51 (CYPL1) (P450-L1A1) (sterol 14-alpha demethylase) (lanosterol 14-alpha demethylase) (P450-14DM) 0.0015 0.0031 0.0006
Schistosoma mansoni sugar transporter 0.0014 0.0025 0.0023
Trichomonas vaginalis PIKK family atypical protein kinase 0.0063 0.106 0.5402
Schistosoma mansoni importin beta-1 0.0028 0.032 0.0449
Echinococcus multilocularis geminin 0.0341 0.6948 1
Trichomonas vaginalis Clan CA, family C1, papain-like cysteine peptidase 0.0034 0.045 0.2292
Echinococcus multilocularis guanine nucleotide binding protein G(s) subunit 0.0089 0.1618 0.2319
Entamoeba histolytica cysteine protease, putative 0.0018 0.0096 0.0417
Entamoeba histolytica hypothetical protein 0.0112 0.2099 1
Echinococcus multilocularis ubiquitin carboxyl terminal hydrolase 8 0.0074 0.1291 0.1848
Mycobacterium tuberculosis Probable cytochrome P450 141 Cyp141 0.0015 0.0031 0.0006
Giardia lamblia Heat shock protein HSP 90-alpha 0.0026 0.0281 0.1322
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0131 0.2498 1
Brugia malayi Hypothetical 52.5 kDa protein ZK945.1 in chromosome II, putative 0.0076 0.133 0.2746
Onchocerca volvulus 0.0076 0.133 1
Trypanosoma cruzi hexose transporter, putative 0.0032 0.0392 0.157
Schistosoma mansoni dihydrolipoamide dehydrogenase 0.0016 0.0059 0.0072
Schistosoma mansoni hypothetical protein 0.0068 0.1168 0.167
Schistosoma mansoni hypothetical protein 0.0047 0.0717 0.1021
Trichomonas vaginalis sugar transporter, putative 0.0014 0.0025 0.0128
Toxoplasma gondii calcium-dependent protein kinase CDPK2A 0.0032 0.0394 0.0659
Trypanosoma brucei protein kinase, putative 0.0052 0.0815 0.3237
Trichomonas vaginalis PIKK family atypical protein kinase 0.0079 0.1388 0.7073
Brugia malayi latrophilin 2 splice variant baaae 0.0068 0.1168 0.2409
Trichomonas vaginalis PIKK family atypical protein kinase 0.0035 0.0472 0.2407
Trichomonas vaginalis PIKK family atypical protein kinase 0.0035 0.0472 0.2407
Trichomonas vaginalis CAMK family protein kinase 0.0032 0.0393 0.2004
Trichomonas vaginalis sugar transporter, putative 0.0014 0.0025 0.0128
Echinococcus multilocularis heat shock protein 0.0033 0.0424 0.0599
Trichomonas vaginalis PIKK family atypical protein kinase 0.002 0.0145 0.0737
Loa Loa (eye worm) hypothetical protein 0.0023 0.0209 0.0341
Loa Loa (eye worm) hypothetical protein 0.0032 0.0393 0.0642
Echinococcus multilocularis mothers against decapentaplegic 5 0.0016 0.0068 0.0085
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0023 0.0209 0.1064
Mycobacterium tuberculosis Probable aldehyde dehydrogenase 0.0062 0.1035 0.1013
Plasmodium falciparum glutathione reductase 0.0046 0.0698 0.0773
Echinococcus multilocularis endoplasmin 0.0026 0.0281 0.0392
Trichomonas vaginalis sugar transporter, putative 0.0014 0.0025 0.0128
Trichomonas vaginalis conserved hypothetical protein 0.0014 0.0025 0.0128
Schistosoma mansoni serine/threonine protein kinase 0.0032 0.0393 0.0554
Schistosoma mansoni ran 0.0021 0.0162 0.022
Echinococcus multilocularis phosphatidylinositol 3 and 4 kinase 0.0035 0.0472 0.0668
Plasmodium vivax thioredoxin reductase, putative 0.0046 0.0698 0.0773
Brugia malayi Cathepsin L-like precursor 0.0034 0.045 0.0916
Trypanosoma cruzi Lanosterol 14-alpha demethylase 0.0015 0.0031 0.0123
Echinococcus multilocularis GA binding protein alpha chain 0.0074 0.1286 0.184
Schistosoma mansoni ataxia telangiectasia mutated (atm)-related 0.0106 0.1962 0.2814
Toxoplasma gondii sugar transporter ST3 0.0014 0.0025 0.0028
Echinococcus multilocularis smad 0.0016 0.0068 0.0085
Trypanosoma brucei glucose transporter, putative 0.0032 0.0392 0.1539
Treponema pallidum heat shock protein 90 0.0026 0.0281 1
Trypanosoma brucei heat shock protein, putative 0.0033 0.0424 0.1669
Trypanosoma cruzi cysteine peptidase, putative 0.0018 0.0096 0.0385
Trypanosoma brucei THT1 - hexose transporter, putative 0.0032 0.0392 0.1539
Plasmodium falciparum proline--tRNA ligase 0.0036 0.0478 0.0526
Leishmania major target of rapamycin kinase (TOR) kinase 3 0.0084 0.1505 0.6011
Entamoeba histolytica ubiquitin carboxyl-terminal hydrolase domain containing protein 0.0074 0.1291 0.6135
Trypanosoma cruzi heat shock protein 85, putative 0.0026 0.0281 0.1125
Echinococcus multilocularis importin subunit beta 1 0.0028 0.032 0.0449
Echinococcus multilocularis lamin 0.0026 0.0282 0.0393
Brugia malayi MH2 domain containing protein 0.0016 0.0068 0.0123
Echinococcus granulosus heat shock protein heat shock protein 90 alpha 0.0026 0.0281 0.0392
Entamoeba histolytica cysteine protease, putative 0.0018 0.0096 0.0417
Plasmodium falciparum hexose transporter 0.0102 0.1886 0.2106
Loa Loa (eye worm) CMGC/MAPK/ERK1 protein kinase 0.0052 0.0815 0.1331
Brugia malayi Cam kinase protein 1 0.0032 0.0393 0.0799
Trypanosoma cruzi cysteine proteinase, putative 0.0018 0.0096 0.0385
Onchocerca volvulus 0.0076 0.133 1
Leishmania major aldehyde dehydrogenase, mitochondrial precursor 0.0062 0.1035 0.4123
Loa Loa (eye worm) hypothetical protein 0.0076 0.133 0.2172
Trypanosoma brucei glucose transporter, putative 0.0032 0.0392 0.1539
Echinococcus multilocularis ubiquitin specific protease 41 0.0074 0.1291 0.1848
Toxoplasma gondii heat shock protein 90, putative 0.0033 0.0424 0.0711
Onchocerca volvulus 0.0014 0.0025 0.0122
Echinococcus granulosus cathepsin L cysteine protease 0.0018 0.0096 0.0126
Echinococcus granulosus phosphatidylinositol 3 and 4 kinase 0.0035 0.0472 0.0668
Brugia malayi Corticotropin releasing factor receptor 2 precursor, putative 0.01 0.1838 0.3802
Echinococcus multilocularis dihydrolipoamide dehydrogenase 0.0016 0.0059 0.0072
Trichomonas vaginalis sugar transporter, putative 0.0014 0.0025 0.0128
Leishmania major heat shock protein 83-1 0.0033 0.0424 0.1669
Loa Loa (eye worm) hypothetical protein 0.0031 0.037 0.0605
Treponema pallidum exodeoxyribonuclease (exoA) 0.0019 0.0128 0.3094
Echinococcus multilocularis solute carrier family 22 0.0014 0.0025 0.0023
Echinococcus granulosus cytochrome P450 2K1 0.0015 0.0031 0.0031
Loa Loa (eye worm) latrophilin receptor protein 2 0.0032 0.0391 0.0638
Giardia lamblia Heat shock protein HSP 90-alpha 0.0033 0.0424 0.2062
Loa Loa (eye worm) hypothetical protein 0.0023 0.0209 0.0341
Chlamydia trachomatis lysine--tRNA ligase 0.0023 0.0204 1
Leishmania major heat shock protein 83-1 0.0033 0.0424 0.1669
Schistosoma mansoni protein kinase 0.0032 0.0393 0.0554
Trypanosoma cruzi cysteine peptidase, clan CA, family C1, cathepsin L-like, putative 0.012 0.2257 0.9035
Trichomonas vaginalis sugar transporter, putative 0.0014 0.0025 0.0128
Entamoeba histolytica cysteine proteinase, putative 0.0034 0.045 0.2108
Mycobacterium ulcerans cytochrome P450 143A4 Cyp143A4 0.0015 0.0031 0.0042
Leishmania major heat shock protein 83-1 0.0033 0.0424 0.1669
Trichomonas vaginalis PIKK family atypical protein kinase 0.009 0.1634 0.833
Plasmodium falciparum dihydrolipoyl dehydrogenase, apicoplast 0.0016 0.0059 0.0056
Echinococcus granulosus Smad4 0.0016 0.0068 0.0085
Mycobacterium tuberculosis Probable hydrolase 0.0076 0.133 0.1308
Trichomonas vaginalis PIKK family atypical protein kinase 0.0084 0.1503 0.7663
Mycobacterium tuberculosis Probable lipase LipD 0.0076 0.133 0.1308
Trichomonas vaginalis heat shock protein, putative 0.0033 0.0424 0.2163
Onchocerca volvulus 0.0014 0.0025 0.0122
Loa Loa (eye worm) hypothetical protein 0.0026 0.0272 0.0444
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0034 0.045 0.2292
Leishmania major heat shock protein 83-1 0.0033 0.0424 0.1669
Echinococcus granulosus Sugar transporter ERD6 protein 0.0014 0.0025 0.0023
Leishmania major heat shock protein 83-1 0.0033 0.0424 0.1669
Schistosoma mansoni endoplasmin 0.0033 0.0424 0.0599
Trichomonas vaginalis heat shock protein, putative 0.0026 0.0281 0.1433
Loa Loa (eye worm) major facilitator superfamily transporter 0.0014 0.0025 0.0041
Loa Loa (eye worm) hypothetical protein 0.0014 0.0025 0.0041
Trypanosoma cruzi heat shock protein 85, putative 0.0033 0.0424 0.1699
Schistosoma mansoni hypothetical protein 0.0102 0.1886 0.2704
Plasmodium vivax lysine--tRNA ligase, putative 0.0023 0.0204 0.0219
Schistosoma mansoni sugar transporter 0.0014 0.0025 0.0023
Schistosoma mansoni hypothetical protein 0.0032 0.0391 0.055
Schistosoma mansoni SmCL2-like peptidase (C01 family) 0.0018 0.0096 0.0126
Mycobacterium ulcerans cytochrome P450 187A5 Cyp187A5 0.0015 0.0031 0.0042
Schistosoma mansoni Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) 0.0089 0.1618 0.2319
Mycobacterium tuberculosis Possible conserved lipoprotein LpqK 0.0076 0.133 0.1308
Trypanosoma brucei Heat shock protein 83, putative 0.0033 0.0424 0.1669
Trypanosoma brucei heat shock protein, putative 0.0033 0.0424 0.1669
Toxoplasma gondii CMGC kinase, MAPK family (ERK) MAPK-1 0.0052 0.0815 0.138
Echinococcus multilocularis solute carrier family 2 facilitated glucose 0.0102 0.1886 0.2704
Trichomonas vaginalis conserved hypothetical protein 0.0014 0.0025 0.0128
Echinococcus multilocularis glutamyl tRNA synthetase cytoplasmic 0.0031 0.037 0.052
Echinococcus multilocularis Sugar transporter ERD6 protein 0.0014 0.0025 0.0023
Onchocerca volvulus 0.0014 0.0025 0.0122
Schistosoma mansoni hypothetical protein 0.0015 0.0031 0.0031
Entamoeba histolytica heat shock protein 90, putative 0.0033 0.0424 0.1988
Echinococcus granulosus importin subunit beta 1 0.0028 0.032 0.0449
Echinococcus granulosus FKBP12 rapamycin complex associated protein 0.0106 0.1962 0.2814
Trypanosoma brucei heat shock protein, putative 0.0033 0.0424 0.1669
Brugia malayi Major Facilitator Superfamily protein 0.0014 0.0025 0.0033
Echinococcus granulosus solute carrier family 22 0.0014 0.0025 0.0023
Mycobacterium tuberculosis Probable esterase/lipase LipP 0.0076 0.133 0.1308
Loa Loa (eye worm) MH2 domain-containing protein 0.024 0.4819 0.7872
Trichomonas vaginalis PIKK family atypical protein kinase 0.0084 0.1503 0.7663
Leishmania major lysyl-tRNA synthetase, putative 0.0023 0.0204 0.0783
Trichomonas vaginalis PIKK family atypical protein kinase 0.0057 0.0931 0.4745
Loa Loa (eye worm) hypothetical protein 0.0026 0.0282 0.0461
Loa Loa (eye worm) hypothetical protein 0.0076 0.133 0.2172
Leishmania major heat shock protein 83-1 0.0033 0.0424 0.1669
Brugia malayi Cytochrome P450 family protein 0.0035 0.0455 0.0928
Toxoplasma gondii exonuclease III APE 0.0019 0.0128 0.0204
Trichomonas vaginalis sugar transporter, putative 0.0014 0.0025 0.0128
Echinococcus multilocularis cathepsin l cysteine peptidase 0.0034 0.045 0.0635
Plasmodium vivax AP endonuclease (DNA-[apurinic or apyrimidinic site] lyase), putative 0.0019 0.0128 0.0133
Schistosoma mansoni sugar transporter 0.0014 0.0025 0.0023
Plasmodium falciparum importin beta, putative 0.0028 0.032 0.0349
Loa Loa (eye worm) transcription factor SMAD2 0.024 0.4819 0.7872
Echinococcus multilocularis FKBP12 rapamycin complex associated protein 0.0106 0.1962 0.2814
Leishmania major heat shock protein 83-1 0.0033 0.0424 0.1669
Brugia malayi Major Facilitator Superfamily protein 0.0014 0.0025 0.0033
Echinococcus granulosus cathepsin L cysteine proteinase 0.0034 0.045 0.0635
Entamoeba histolytica protein kinase, putative 0.0032 0.0393 0.1838
Mycobacterium tuberculosis Probable cytochrome P450 144 Cyp144 0.0015 0.0031 0.0006
Mycobacterium ulcerans cytochrome P450 126A3 Cyp126A3 0.0015 0.0031 0.0042
Trypanosoma cruzi ubiquitin carboxyl-terminal hydrolase, putative 0.0074 0.1291 0.5168
Brugia malayi hypothetical protein 0.0014 0.0025 0.0033
Echinococcus granulosus diuretic hormone 44 receptor GPRdih2 0.0032 0.0391 0.055
Loa Loa (eye worm) fibroinase 0.0034 0.045 0.0735
Loa Loa (eye worm) phosphatidylinositol 3 0.0106 0.1962 0.3205
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0034 0.045 0.2292
Trypanosoma cruzi cysteine peptidase, putative 0.0131 0.2498 1
Schistosoma mansoni hypothetical protein 0.0302 0.6122 0.8809
Brugia malayi Fli-1 protein 0.0224 0.4472 0.928
Echinococcus multilocularis cysteine protease 0.0034 0.045 0.0635
Trichomonas vaginalis PIKK family atypical protein kinase 0.0057 0.0929 0.4735
Entamoeba histolytica cysteine proteinase, putative 0.0018 0.0096 0.0417
Plasmodium vivax proline--tRNA ligase, putative 0.0036 0.0478 0.0526
Trichomonas vaginalis sugar transporter, putative 0.0032 0.0392 0.1999
Echinococcus granulosus lamin 0.0026 0.0282 0.0393
Plasmodium falciparum cysteine proteinase falcipain 3 0.0034 0.045 0.0495
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0131 0.2498 1
Loa Loa (eye worm) thioredoxin reductase 0.0046 0.0698 0.114
Trypanosoma cruzi GTP-binding nuclear protein rtb2, putative 0.0021 0.0162 0.0649
Trypanosoma cruzi cytochrome P450, putative 0.0032 0.0408 0.1633
Brugia malayi Ets-domain containing protein 0.0074 0.1286 0.2655
Schistosoma mansoni protein kinase 0.0032 0.0393 0.0554
Brugia malayi MH2 domain containing protein 0.024 0.4819 1
Loa Loa (eye worm) hypothetical protein 0.0014 0.0025 0.0041
Trichomonas vaginalis heat shock protein, putative 0.0026 0.0281 0.1433
Wolbachia endosymbiont of Brugia malayi dihydrolipoamide dehydrogenase E3 component 0.0016 0.0059 0.1333
Schistosoma mansoni TGF-beta signal transducer Smad2 0.0016 0.0068 0.0085
Brugia malayi Cathepsin L-like precursor 0.0034 0.045 0.0916
Leishmania major mitogen activated protein kinase, putative,map kinase, putative 0.0052 0.0815 0.3237
Trypanosoma brucei heat shock protein 90, putative 0.0033 0.0424 0.1669
Trypanosoma cruzi Heat shock protein 83, putative 0.0033 0.0424 0.1699
Echinococcus granulosus solute carrier family 2 facilitated glucose 0.0102 0.1886 0.2704
Echinococcus granulosus calcium dependent protein kinase 0.0029 0.0343 0.0481
Leishmania major heat shock protein 83-1 0.0033 0.0424 0.1669
Brugia malayi lysyl-tRNA synthetase 0.0023 0.0204 0.0405
Loa Loa (eye worm) endoplasmin 0.0033 0.0424 0.0693
Onchocerca volvulus Cathepsin F homolog 0.0034 0.045 0.3337
Loa Loa (eye worm) hypothetical protein 0.0074 0.1291 0.2109
Brugia malayi major facilitator superfamily protein 0.0014 0.0025 0.0033
Trypanosoma brucei glucose transporter, putative 0.0032 0.0392 0.1539
Echinococcus multilocularis solute carrier family 22 0.0014 0.0025 0.0023
Trichomonas vaginalis PIKK family atypical protein kinase 0.0035 0.0472 0.2407
Trichomonas vaginalis PIKK family atypical protein kinase 0.0063 0.106 0.5402
Trichomonas vaginalis Clan CA, family C1, papain-like cysteine peptidase 0.0034 0.045 0.2292
Loa Loa (eye worm) hypothetical protein 0.0014 0.0025 0.0041
Leishmania major 2-oxoglutarate dehydrogenase, e3 component, lipoamidedehydrogenase-like protein 0.0016 0.0059 0.0202
Leishmania major lanosterol 14-alpha-demethylase, putative 0.0015 0.0031 0.0087
Mycobacterium ulcerans cytochrome P450 189A7 Cyp189A7 0.0015 0.0031 0.0042
Echinococcus granulosus glutamyl tRNA synthetase cytoplasmic 0.0031 0.037 0.052
Brugia malayi Calcitonin receptor-like protein seb-1 0.01 0.1838 0.3802
Mycobacterium tuberculosis Probable dehydrogenase 0.0105 0.1949 0.1929
Toxoplasma gondii lysine-tRNA ligase 0.0023 0.0204 0.0334
Loa Loa (eye worm) hypothetical protein 0.002 0.0145 0.0236
Schistosoma mansoni glutamyl-tRNA synthetase cytoplasmic (glutamate--tRNA ligase) (glurs) 0.0031 0.037 0.052
Loa Loa (eye worm) GTP-binding regulatory protein Gs alpha-S chain 0.0089 0.1618 0.2643
Brugia malayi cytoplasmic intermediate filament protein 0.0014 0.0021 0.0026
Schistosoma mansoni survival motor neuron protein 0.0047 0.0717 0.1021
Echinococcus multilocularis solute carrier family 22 0.0014 0.0025 0.0023
Trypanosoma brucei importin beta-1 subunit, putative 0.0028 0.032 0.1251
Loa Loa (eye worm) hypothetical protein 0.01 0.1838 0.3002
Loa Loa (eye worm) hypothetical protein 0.0014 0.0025 0.0041
Trichomonas vaginalis sugar transporter, putative 0.0014 0.0025 0.0128
Mycobacterium tuberculosis Probable cytochrome P450 130 Cyp130 0.0015 0.0031 0.0006
Echinococcus granulosus PIK kinase FAT and Armadillo domain containing protein 0.0015 0.0048 0.0057
Trypanosoma cruzi prolyl-tRNA synthetase, putative 0.0036 0.0478 0.1913
Entamoeba histolytica hypothetical protein 0.0023 0.0204 0.0933
Mycobacterium tuberculosis Probable cytochrome P450 132 Cyp132 0.0015 0.0031 0.0006
Trichomonas vaginalis D-aminoacylase, putative 0.0076 0.133 0.6777
Plasmodium falciparum heat shock protein 90 0.0033 0.0424 0.0466
Mycobacterium ulcerans cytochrome P450 140A5 Cyp140A5 0.0015 0.0031 0.0042
Leishmania major heat shock protein 83-1 0.0033 0.0424 0.1669
Loa Loa (eye worm) hypothetical protein 0.0022 0.0193 0.0315
Plasmodium vivax vivapain-2 0.0034 0.045 0.0495
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0034 0.045 0.2292
Trichomonas vaginalis PIKK family atypical protein kinase 0.0084 0.1503 0.7663
Entamoeba histolytica cysteine proteinase 2 0.0018 0.0096 0.0417
Schistosoma mansoni Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) 0.0089 0.1618 0.2319
Trypanosoma cruzi heat shock protein 90, putative 0.0026 0.0281 0.1125
Trichomonas vaginalis sugar transporter, putative 0.0014 0.0025 0.0128
Schistosoma mansoni ets-related 0.0224 0.4472 0.6432
Trichomonas vaginalis PIKK family atypical protein kinase 0.0035 0.0472 0.2407
Loa Loa (eye worm) exodeoxyribonuclease III family protein 0.0019 0.0128 0.0209
Loa Loa (eye worm) hypothetical protein 0.0014 0.0025 0.0041
Brugia malayi hypothetical protein 0.023 0.4606 0.9559

Activities

No activities found for this compound.

Phenotypes

Whole-cell/tissue/organism interactions

We have no records of whole-cell/tissue assays done with this compound What does this mean?

Many chemical entities in TDR Targets come from high-throughput screenings with whole cells or tissue samples, and not all assayed compounds have been tested against a single a single target protein, probably because they get ruled out during screening process. Even if these compounds may have not been of interest in the original screening, they may come as interesting leads for other screening assays. Furthermore, we may be able to propose drug-target associations using chemical similarities and network patterns.

Annotated phenotypes:

We have no manually annotated phenotypes for this drug. What does this mean? / Care to help?
In TDR Targets, information about phenotypes that are caused by drugs, or by genetic manipulation of cells (e.g. gene knockouts or knockdowns) is manually curated from the literature. These descriptions help to describe the potential of the target for drug development. If no information is available for this gene or if the information is incomplete, this may mean that i) the papers containing this information either appeared after the curation effort for this organism was carried out or they were inadvertently missed by curators; or that ii) the curation effort for this organism has not yet started.
 
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External resources for this compound

Bibliographic References

No literature references available for this target.

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