Detailed information for compound 833154

Basic information

Technical information
  • TDR Targets ID: 833154
  • Name: 2-(7-tert-butyl-4-oxo-5,6,7,8-tetrahydro-[1]b enzothiolo[2,3-d]triazin-3-yl)-N-(4-methoxy-2 -nitrophenyl)acetamide
  • MW: 471.529 | Formula: C22H25N5O5S
  • H donors: 1 H acceptors: 4 LogP: 5.69 Rotable bonds: 7
    Rule of 5 violations (Lipinski): 1
  • SMILES: COc1ccc(c(c1)[N+](=O)[O-])NC(=O)Cn1nnc2c(c1=O)c1CCC(Cc1s2)C(C)(C)C
  • InChi: 1S/C22H25N5O5S/c1-22(2,3)12-5-7-14-17(9-12)33-20-19(14)21(29)26(25-24-20)11-18(28)23-15-8-6-13(32-4)10-16(15)27(30)31/h6,8,10,12H,5,7,9,11H2,1-4H3,(H,23,28)
  • InChiKey: QSZGQBSFZBWVTH-UHFFFAOYSA-N  


Substructure search Similarity search

Network

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Synonyms

  • 2-(7-tert-butyl-4-oxo-5,6,7,8-tetrahydrobenzothiopheno[2,3-d]triazin-3-yl)-N-(4-methoxy-2-nitro-phenyl)acetamide
  • 2-(7-tert-butyl-4-oxo-5,6,7,8-tetrahydrobenzothiopheno[2,3-d]triazin-3-yl)-N-(4-methoxy-2-nitrophenyl)acetamide
  • 2-(7-tert-butyl-4-keto-5,6,7,8-tetrahydrobenzothiopheno[2,3-d]triazin-3-yl)-N-(4-methoxy-2-nitro-phenyl)acetamide
  • 2-(7-tert-butyl-4-oxo-5,6,7,8-tetrahydro-[1]benzothiolo[2,3-d][1,2,3]triazin-3-yl)-N-(4-methoxy-2-nitro-phenyl)ethanamide

Targets

Known targets for this compound

No curated genes were found associated with this compound

Predicted pathogen targets for this compound

By orthology
No druggable targets predicted by orthology data
By sequence similarity to non orthologous known druggable targets
No druggable targets predicted by sequence similarity
Obtained from network model

Ranking Plot

Putative Targets List

Species Potential target Raw Global Species
Loa Loa (eye worm) hypoxia-induced factor 1 0.0296 0.1806 0.2705
Trypanosoma brucei alpha tubulin 0.0807 0.5039 0.7558
Brugia malayi Nuclear hormone receptor-like 1 0.0027 0.011 0.0159
Schistosoma mansoni thyroid hormone receptor 0.0027 0.011 0.0129
Leishmania major target of rapamycin (TOR) kinase 2, putative 0.0044 0.0219 0.0323
Echinococcus granulosus ATP dependent DNA helicase Q5 0.0019 0.006 0.0066
Onchocerca volvulus 0.0235 0.1424 0.7082
Trypanosoma cruzi isocitrate dehydrogenase [NADP], mitochondrial precursor, putative 0.0015 0.0035 0.0047
Trypanosoma cruzi PAB1-binding protein , putative 0.0049 0.0251 0.037
Schistosoma mansoni nuclear hormone receptor 0.0027 0.011 0.0129
Brugia malayi Nuclear hormone receptor E75 0.0013 0.0019 0.0023
Trichomonas vaginalis tubulin beta chain, putative 0.0807 0.5039 0.7555
Echinococcus multilocularis histone lysine N methyltransferase SETMAR 0.003 0.0128 0.0125
Brugia malayi Nuclear hormone receptor family member nhr-40 0.0027 0.011 0.0159
Leishmania major beta tubulin 0.1064 0.6665 1
Entamoeba histolytica recQ family helicase, putative 0.0019 0.006 0.009
Onchocerca volvulus 0.0026 0.0104 0.0428
Echinococcus multilocularis tubulin alpha chain 0.0807 0.5039 0.5037
Loa Loa (eye worm) hypothetical protein 0.0055 0.0287 0.0424
Echinococcus granulosus death domain containing protein 0.0014 0.0026 0.0026
Brugia malayi Cytochrome P450 family protein 0.0028 0.0113 0.0163
Brugia malayi Tubulin alpha-2 chain 0.0807 0.5039 0.7558
Brugia malayi bZIP transcription factor family protein 0.0082 0.0455 0.0677
Trichomonas vaginalis adenylate cyclase, type VII, putative 0.0025 0.0095 0.0122
Echinococcus multilocularis Nuclear hormone receptor family member nhr 41 0.0027 0.011 0.0106
Trypanosoma cruzi dihydrolipoyl dehydrogenase, putative 0.0016 0.004 0.0055
Mycobacterium tuberculosis Cell division protein FtsZ 0.0269 0.164 1
Brugia malayi Pre-SET motif family protein 0.0207 0.1243 0.1861
Trypanosoma cruzi Phosphatidylinositol 3-kinase tor1 0.0044 0.0219 0.0323
Trypanosoma cruzi target of rapamycin kinase 3 0.0035 0.0162 0.0237
Schistosoma mansoni hypothetical protein 0.0152 0.0898 0.1056
Echinococcus multilocularis ATP binding cassette subfamily B (MDR:TAP) 0.0021 0.007 0.0066
Trichomonas vaginalis tubulin, putative 0.1064 0.6665 1
Echinococcus multilocularis tubulin, beta 4A class IVa 0.1064 0.6665 0.6664
Trichomonas vaginalis tubulin, putative 0.0296 0.1809 0.2699
Entamoeba histolytica hypothetical protein 0.0071 0.0384 0.0576
Brugia malayi sodium-independent organic anion transporter family protein 0.0055 0.0287 0.0424
Trichomonas vaginalis conserved hypothetical protein 0.0041 0.0198 0.0278
Echinococcus multilocularis ATP binding cassette subfamily B (MDR:TAP) 0.0021 0.007 0.0066
Trichomonas vaginalis multidrug resistance protein 1, 2, putative 0.0021 0.007 0.0085
Leishmania major alpha tubulin 0.0807 0.5039 0.7558
Schistosoma mansoni histone-lysine n-methyltransferase setb1 0.003 0.0128 0.0151
Trypanosoma brucei tyrosyl-DNA Phosphodiesterase (Tdp1), putative 0.0064 0.0344 0.0511
Trichomonas vaginalis multidrug resistance protein 1, 2, putative 0.0021 0.007 0.0085
Brugia malayi Phosphatidylinositol 3- and 4-kinase family protein 0.0015 0.0032 0.0042
Brugia malayi Kazal-type serine protease inhibitor domain containing protein 0.0038 0.0176 0.0258
Trichomonas vaginalis PIKK family atypical protein kinase 0.0015 0.0032 0.0028
Schistosoma mansoni netrin receptor unc5 0.0014 0.0026 0.0031
Echinococcus granulosus tubulin alpha 1C chain 0.0807 0.5039 0.5926
Brugia malayi beta-tubulin, identical 0.1064 0.6665 1
Leishmania major ubiquitin hydrolase, putative,cysteine peptidase, Clan CA, family C19, putative 0.0036 0.0165 0.0243
Toxoplasma gondii Kazal-type serine protease inhibitor domain-containing protein 0.0038 0.0176 0.0264
Trypanosoma cruzi zeta tubulin, putative 0.0545 0.3384 0.5075
Echinococcus multilocularis nuclear receptor nhr 48 0.0013 0.0019 0.0015
Echinococcus granulosus ATP binding cassette subfamily B MDR:TAP 0.0021 0.007 0.0077
Loa Loa (eye worm) tubulin beta chain 0.1064 0.6665 1
Schistosoma mansoni single-minded 0.0096 0.0541 0.0637
Echinococcus granulosus tubulin alpha chain 0.0807 0.5039 0.5926
Echinococcus multilocularis beta tubulin 0.1064 0.6665 0.6664
Trichomonas vaginalis tubulin alpha-1 chain, putative 0.048 0.2974 0.4451
Toxoplasma gondii histone lysine methyltransferase SET/SUV39 0.003 0.0128 0.0193
Leishmania major target of rapamycin kinase (TOR) kinase 3 0.0035 0.0162 0.0237
Loa Loa (eye worm) hypothetical protein 0.0026 0.0101 0.0145
Echinococcus granulosus agrin 0.0038 0.0176 0.0203
Trichomonas vaginalis conserved hypothetical protein 0.0025 0.0095 0.0122
Plasmodium falciparum dihydrolipoyl dehydrogenase, apicoplast 0.0016 0.004 0.0009
Trypanosoma brucei alpha tubulin 0.0807 0.5039 0.7558
Loa Loa (eye worm) beta-tubulin 0.1064 0.6665 1
Echinococcus multilocularis lysine specific demethylase 6a 0.0015 0.0034 0.003
Trichomonas vaginalis ATP-binding cassette transporter, putative 0.0021 0.007 0.0085
Trichomonas vaginalis ABC transporter, putative 0.0021 0.007 0.0085
Trichomonas vaginalis tubulin alpha-1 chain, putative 0.0807 0.5039 0.7555
Trichomonas vaginalis conserved hypothetical protein 0.0036 0.0165 0.0229
Echinococcus multilocularis tubulin alpha 3 chain 0.0807 0.5039 0.5037
Echinococcus multilocularis Nuclear hormone receptor HR96 0.0013 0.0019 0.0015
Trichomonas vaginalis lipid A export ATP-binding/permease protein msba, putative 0.0021 0.007 0.0085
Echinococcus granulosus cpg binding protein 0.003 0.0125 0.0142
Schistosoma mansoni TGF-beta signal transducer Smad2 0.0016 0.0039 0.0046
Brugia malayi Nuclear hormone receptor family member nhr-25 0.0027 0.011 0.0159
Brugia malayi secreted modular calcium-binding protein 1 0.0038 0.0176 0.0258
Echinococcus granulosus lysine specific demethylase 6a 0.0015 0.0034 0.0036
Echinococcus multilocularis tubulin alpha 3 chain 0.0807 0.5039 0.5037
Leishmania major beta tubulin 0.1064 0.6665 1
Mycobacterium tuberculosis Probable dehydrogenase 0.0107 0.0612 0.372
Leishmania major alpha tubulin 0.0807 0.5039 0.7558
Echinococcus granulosus transcription factor Dp 1 0.0037 0.0173 0.0199
Brugia malayi hypothetical protein 0.0013 0.0019 0.0023
Leishmania major cytochrome p450-like protein 0.0028 0.0113 0.0163
Loa Loa (eye worm) hypothetical protein 0.005 0.0256 0.0379
Leishmania major hypothetical protein, conserved 0.0015 0.0034 0.0046
Loa Loa (eye worm) hypothetical protein 0.0014 0.0027 0.0035
Trichomonas vaginalis PIKK family atypical protein kinase 0.0027 0.0106 0.0139
Echinococcus multilocularis neuropeptide receptor A26 0.0452 0.2794 0.2791
Loa Loa (eye worm) glutathione reductase 0.0047 0.0234 0.0345
Schistosoma mansoni agrin 0.0038 0.0176 0.0207
Loa Loa (eye worm) BEN-1 protein 0.1064 0.6665 1
Echinococcus granulosus Tubulin beta 2C chain 0.1064 0.6665 0.784
Giardia lamblia Kinase, CMGC MAPK 0.01 0.057 0.08
Brugia malayi dihydrolipoyl dehydrogenase, mitochondrial precursor, putative 0.0016 0.004 0.0055
Schistosoma mansoni organic anion transporter 0.0055 0.0287 0.0337
Echinococcus multilocularis mitogen activated protein kinase 0.01 0.057 0.0566
Trichomonas vaginalis tubulin beta-1 chain, putative 0.0269 0.164 0.2445
Schistosoma mansoni multidrug resistance protein 0.0021 0.007 0.0082
Trypanosoma cruzi mitogen activated protein kinase 4, putative 0.01 0.057 0.085
Schistosoma mansoni hypothetical protein 0.001 0.0004 0.0005
Brugia malayi ecdysteroid receptor 0.0027 0.011 0.0159
Trichomonas vaginalis lipid A export ATP-binding/permease protein msba, putative 0.0021 0.007 0.0085
Brugia malayi Nuclear hormone receptor family member nhr-31 0.0027 0.011 0.0159
Trichomonas vaginalis PIKK family atypical protein kinase 0.0029 0.012 0.0161
Schistosoma mansoni hypothetical protein 0.0066 0.0358 0.0421
Loa Loa (eye worm) hypothetical protein 0.0013 0.0019 0.0023
Echinococcus granulosus Solute carrier organic anion transporter family 0.0055 0.0287 0.0333
Brugia malayi Kazal-type serine protease inhibitor domain containing protein 0.0038 0.0176 0.0258
Echinococcus granulosus Peptidase C19 ubiquitin carboxyl terminal hydrolase 2 0.0036 0.0165 0.019
Echinococcus multilocularis ATP binding cassette sub family B 0.0021 0.0068 0.0064
Trichomonas vaginalis tubulin epsilon chain, putative 0.1064 0.6665 1
Echinococcus granulosus jun protein 0.0082 0.0455 0.0531
Leishmania major beta tubulin 0.1064 0.6665 1
Echinococcus multilocularis NADP dependent isocitrate dehydrogenase 0.0015 0.0035 0.0031
Brugia malayi hypothetical protein 0.0014 0.0029 0.0037
Treponema pallidum cell division protein FtsZ 0.0269 0.164 1
Echinococcus granulosus lipoxygenase domain containing protein 0.0059 0.0308 0.0358
Mycobacterium leprae Possible regulatory protein 0.0025 0.0095 0.0555
Schistosoma mansoni thyroid hormone receptor 0.0027 0.011 0.0129
Trichomonas vaginalis tubulin, putative 0.0327 0.2003 0.2991
Trichomonas vaginalis PIKK family atypical protein kinase 0.0044 0.0219 0.0309
Brugia malayi Cytochrome P450 family protein 0.0028 0.0113 0.0163
Echinococcus granulosus neuropeptide receptor A26 0.0452 0.2794 0.3284
Echinococcus granulosus nuclear receptor nhr 48 0.0013 0.0019 0.0018
Brugia malayi Pyridine nucleotide-disulphide oxidoreductase, dimerisation domain containing protein 0.0012 0.0013 0.0014
Toxoplasma gondii transporter, major facilitator family protein 0.0055 0.0287 0.043
Trichomonas vaginalis tubulin gamma chain, putative 0.0622 0.3871 0.5799
Loa Loa (eye worm) hypothetical protein 0.0026 0.0104 0.015
Loa Loa (eye worm) RecQ helicase 0.0019 0.006 0.0084
Plasmodium falciparum LCCL domain-containing protein 0.0059 0.0308 0.0412
Trypanosoma cruzi STE/STE11 serine/threonine-protein kinase, putative 0.0026 0.01 0.0145
Plasmodium vivax SET domain protein, putative 0.003 0.0128 0.0193
Toxoplasma gondii histone lysine demethylase JMJC1/KDM5D/JARID1D 0.0015 0.0034 0.0052
Onchocerca volvulus Huntingtin homolog 0.0119 0.0692 0.3392
Brugia malayi nuclear receptor NHR-67 0.0013 0.0019 0.0023
Echinococcus multilocularis dnaJ subfamily B 0.0398 0.2455 0.2452
Trichomonas vaginalis soluble guanylate cyclase gcy, putative 0.0025 0.0095 0.0122
Trichomonas vaginalis conserved hypothetical protein 0.0025 0.0095 0.0122
Schistosoma mansoni tubulin subunit alpha 0.0807 0.5039 0.5928
Loa Loa (eye worm) thioredoxin reductase 0.0047 0.0234 0.0345
Leishmania major protein kinase, putative 0.0026 0.01 0.0145
Trichomonas vaginalis PIKK family atypical protein kinase 0.0033 0.0147 0.0201
Entamoeba histolytica P-glycoprotein 5, putative 0.0021 0.007 0.0105
Loa Loa (eye worm) doublecortin family protein 0.0059 0.0308 0.0456
Trichomonas vaginalis DNA helicase recq, putative 0.0019 0.006 0.007
Trichomonas vaginalis abcb9, putative 0.0021 0.007 0.0085
Mycobacterium leprae cell division protein FtsZ 0.0269 0.164 1
Trypanosoma cruzi dihydrolipoamide dehydrogenase, putative 0.0016 0.004 0.0055
Schistosoma mansoni tubulin subunit gamma 0.0623 0.3873 0.4557
Mycobacterium ulcerans putative regulatory protein 0.0071 0.0385 0.2327
Schistosoma mansoni cytochrome P450 0.001 0.0004 0.0005
Schistosoma mansoni retinoblastoma-binding protein 4 (rbbp4) 0.0014 0.0027 0.0032
Echinococcus multilocularis tubulin subunit TubB 0.0807 0.5039 0.5037
Echinococcus granulosus intermediate filament protein 0.0026 0.0104 0.0118
Trichomonas vaginalis tubulin epsilon chain, putative 0.0807 0.5039 0.7555
Trichomonas vaginalis conserved hypothetical protein 0.0269 0.164 0.2445
Brugia malayi Tyrosyl-DNA phosphodiesterase family protein 0.0064 0.0344 0.0511
Echinococcus multilocularis tubulin alpha chain 0.0807 0.5039 0.5037
Loa Loa (eye worm) hypothetical protein 0.0013 0.0019 0.0023
Trypanosoma cruzi phosphatidylinositol 3-related kinase, putative 0.0015 0.0032 0.0042
Echinococcus granulosus Tubulin beta 2C chain 0.1064 0.6665 0.784
Onchocerca volvulus 0.0047 0.0235 0.1087
Loa Loa (eye worm) CYP4Cod1 0.0028 0.0113 0.0163
Brugia malayi hypothetical protein 0.0059 0.0308 0.0456
Leishmania major beta tubulin 0.1064 0.6665 1
Leishmania major beta tubulin 0.1064 0.6665 1
Echinococcus granulosus smad 0.0016 0.0039 0.0041
Leishmania major beta tubulin 0.1064 0.6665 1
Trichomonas vaginalis ABC transporter, putative 0.0021 0.007 0.0085
Schistosoma mansoni rab6-interacting 0.0059 0.0308 0.0362
Trypanosoma brucei tubulin gamma chain 0.0623 0.3873 0.5809
Leishmania major beta tubulin 0.1064 0.6665 1
Toxoplasma gondii protease inhibitor PI2 0.0038 0.0176 0.0264
Schistosoma mansoni ubiquitously transcribed sex (X/Y) chromosome tetratricopeptide repeat protein-related 0.0015 0.0034 0.004
Loa Loa (eye worm) MH2 domain-containing protein 0.0016 0.0039 0.0052
Schistosoma mansoni multidrug resistance protein 0.0021 0.007 0.0082
Echinococcus multilocularis Tubulin alpha 1 chain 0.0807 0.5039 0.5037
Trypanosoma cruzi STE group serine/threonine-protein kinase, putative 0.0026 0.01 0.0145
Trichomonas vaginalis abcb9, putative 0.0021 0.007 0.0085
Trichomonas vaginalis DNA helicase recq, putative 0.0019 0.006 0.007
Trichomonas vaginalis adenylate and guanylate cyclases, putative 0.0025 0.0095 0.0122
Trypanosoma cruzi tyrosyl-DNA Phosphodiesterase (Tdp1), putative 0.0064 0.0344 0.0511
Echinococcus multilocularis protein dispatched 1 0.0047 0.0235 0.0231
Echinococcus granulosus phd:f box containing protein 0.0015 0.0034 0.0036
Loa Loa (eye worm) hypothetical protein 0.0049 0.0251 0.037
Echinococcus granulosus Tubulin beta 2C chain 0.1064 0.6665 0.784
Schistosoma mansoni histone-lysine n-methyltransferase setb1 0.003 0.0128 0.0151
Schistosoma mansoni alpha tubulin 0.0807 0.5039 0.5928
Loa Loa (eye worm) hypothetical protein 0.0038 0.0176 0.0258
Trypanosoma cruzi dihydrolipoamide dehydrogenase, putative 0.0016 0.004 0.0055
Brugia malayi Immunoglobulin I-set domain containing protein 0.0014 0.0026 0.0034
Trichomonas vaginalis guanylate cyclase, putative 0.0025 0.0095 0.0122
Brugia malayi Kazal-type serine protease inhibitor domain containing protein 0.0038 0.0176 0.0258
Brugia malayi jmjC domain containing protein 0.0059 0.031 0.0459
Brugia malayi nuclear receptor RXR 0.0014 0.0029 0.0037
Trichomonas vaginalis Clan CA, family C19, ubiquitin hydrolase-like cysteine peptidase 0.0036 0.0165 0.0229
Brugia malayi Ligand-binding domain of nuclear hormone receptor family protein 0.0027 0.011 0.0159
Trichomonas vaginalis PIKK family atypical protein kinase 0.0038 0.0178 0.0247
Echinococcus granulosus tubulin alpha 0.0596 0.3704 0.4355
Echinococcus granulosus tubulin alpha chain 0.0807 0.5039 0.5926
Mycobacterium leprae DIHYDROLIPOAMIDE DEHYDROGENASE LPD (LIPOAMIDE REDUCTASE (NADH)) (LIPOYL DEHYDROGENASE) (DIHYDROLIPOYL DEHYDROGENASE) (DIAPHORASE 0.0119 0.0688 0.418
Toxoplasma gondii ATP-dependent DNA helicase, RecQ family protein 0.0019 0.006 0.009
Echinococcus granulosus tubulin alpha 1C chain 0.0807 0.5039 0.5926
Onchocerca volvulus 0.0055 0.0287 0.1349
Schistosoma mansoni microtubule-associated protein tau 0.1355 0.8501 1
Echinococcus granulosus netrin receptor unc 5 0.0014 0.0026 0.0026
Leishmania major protein kinase, putative 0.0026 0.01 0.0145
Echinococcus granulosus peroxisome assembly protein 26 0.0807 0.5039 0.5926
Echinococcus granulosus nuclear factor of activated T cells 5 0.0072 0.0391 0.0456
Trichomonas vaginalis PIKK family atypical protein kinase 0.0035 0.0161 0.0223
Brugia malayi intermediate filament protein 0.0026 0.0104 0.015
Trypanosoma brucei phosphatidylinositol 4-kinase, putative 0.0044 0.0219 0.0323
Echinococcus multilocularis Tubulin beta 2C chain 0.1064 0.6665 0.6664
Schistosoma mansoni jumonji/arid domain-containing protein 0.0059 0.031 0.0365
Echinococcus granulosus mitogen activated protein kinase 3 0.01 0.057 0.0666
Toxoplasma gondii Kazal-type serine protease inhibitor domain-containing protein 0.0038 0.0176 0.0264
Echinococcus multilocularis isocitrate dehydrogenase 0.0015 0.0035 0.0031
Mycobacterium tuberculosis Dihydrolipoamide dehydrogenase LpdC (lipoamide reductase (NADH)) (lipoyl dehydrogenase) (dihydrolipoyl dehydrogenase) (diaphoras 0.0119 0.0688 0.418
Trypanosoma brucei phosphatidylinositol 3-kinase tor, putative 0.0021 0.0071 0.01
Echinococcus multilocularis musashi 0.0026 0.0104 0.01
Mycobacterium tuberculosis NADPH-dependent mycothiol reductase Mtr 0.0047 0.0234 0.1404
Trypanosoma cruzi PAB1-binding protein , putative 0.0049 0.0251 0.037
Trypanosoma cruzi PAS-domain containing phosphoglycerate kinase, putative 0.0025 0.0095 0.0136
Echinococcus multilocularis ubiquitin specific protease 41 0.0036 0.0165 0.0162
Echinococcus granulosus lamin 0.0026 0.0104 0.0118
Loa Loa (eye worm) hypothetical protein 0.0014 0.0029 0.0037
Brugia malayi isocitrate dehydrogenase 0.0015 0.0035 0.0047
Schistosoma mansoni hypothetical protein 0.0333 0.204 0.24
Trypanosoma cruzi ubiquitin carboxyl-terminal hydrolase, putative 0.0036 0.0165 0.0243
Schistosoma mansoni DNA helicase recq5 0.0019 0.006 0.007
Entamoeba histolytica ubiquitin carboxyl-terminal hydrolase domain containing protein 0.0036 0.0165 0.0248
Schistosoma mansoni follistatin 0.0038 0.0176 0.0207
Leishmania major epsilon tubulin, putative 0.0622 0.3871 0.5805
Leishmania major beta tubulin 0.1064 0.6665 1
Trichomonas vaginalis tubulin beta chain, putative 0.0807 0.5039 0.7555
Trichomonas vaginalis tubulin alpha chain, putative 0.0596 0.3704 0.5549
Echinococcus multilocularis histone lysine methyltransferase setb histone lysine methyltransferase eggless 0.003 0.0128 0.0125
Echinococcus granulosus sterol regulatory element binding protein 0.0041 0.0198 0.0228
Schistosoma mansoni lipoxygenase 0.0121 0.07 0.0824
Loa Loa (eye worm) cytochrome P450 family protein 0.0028 0.0113 0.0163
Leishmania major alpha tubulin 0.0807 0.5039 0.7558
Echinococcus multilocularis beta tubulin 0.1064 0.6665 0.6664
Brugia malayi Ligand-binding domain of nuclear hormone receptor family protein 0.0027 0.011 0.0159
Trypanosoma cruzi tubulin delta chain 0.0434 0.2683 0.4022
Leishmania major alpha tubulin 0.0807 0.5039 0.7558
Entamoeba histolytica tubulin family protein 0.1064 0.6665 1
Toxoplasma gondii ABC transporter transmembrane region domain-containing protein 0.0021 0.007 0.0105
Trypanosoma cruzi Phosphatidylinositol 3-kinase tor2 0.0044 0.0219 0.0323
Brugia malayi orphan nuclear receptor NR2E1 0.0013 0.0019 0.0023
Trichomonas vaginalis Clan CA, family C19, ubiquitin hydrolase-like cysteine peptidase 0.0036 0.0165 0.0229
Leishmania major beta tubulin 0.1064 0.6665 1
Echinococcus granulosus expressed conserved protein 0.009 0.0507 0.0592
Echinococcus granulosus nuclear receptor 2DBD gamma 0.0027 0.011 0.0125
Echinococcus granulosus hepatocyte nuclear factor 4 alpha 0.0027 0.011 0.0125
Loa Loa (eye worm) hypothetical protein 0.0027 0.011 0.0159
Echinococcus multilocularis transfer RNA-Lys 0.0071 0.0385 0.0381
Echinococcus multilocularis arachidonate 5 lipoxygenase 0.0226 0.1366 0.1363
Plasmodium falciparum glutathione reductase 0.0016 0.004 0.0009
Mycobacterium tuberculosis Probable transmembrane multidrug efflux pump 0.0021 0.007 0.0402
Trypanosoma cruzi ATP-dependent DEAD/H DNA helicase recQ, putative 0.0019 0.006 0.0084
Leishmania major beta tubulin 0.1064 0.6665 1
Loa Loa (eye worm) hypothetical protein 0.0015 0.0034 0.0046
Trichomonas vaginalis DNA helicase recq1, putative 0.0019 0.006 0.007
Echinococcus multilocularis protein patched 0.0041 0.0198 0.0194
Loa Loa (eye worm) steroid hormone receptor 0.0027 0.011 0.0159
Echinococcus multilocularis follistatin 0.0038 0.0176 0.0172
Schistosoma mansoni jun-related protein 0.0066 0.0358 0.0421
Loa Loa (eye worm) ATP-binding cassette sub-family B member 2 0.0021 0.007 0.0099
Echinococcus granulosus Niemann Pick C1 protein 0.0096 0.0544 0.0635
Brugia malayi jmjC domain containing protein 0.0015 0.0034 0.0046
Echinococcus multilocularis lamin 0.0026 0.0104 0.01
Trichomonas vaginalis tubulin epsilon chain, putative 0.0807 0.5039 0.7555
Echinococcus multilocularis thyroid hormone receptor alpha 0.0027 0.011 0.0106
Mycobacterium ulcerans cell division protein FtsZ 0.0269 0.164 1
Trypanosoma cruzi dihydrolipoyl dehydrogenase, putative 0.0016 0.004 0.0055
Echinococcus multilocularis tubulin alpha chain 0.0807 0.5039 0.5037
Leishmania major beta tubulin 0.1064 0.6665 1
Loa Loa (eye worm) cytochrome P450 family protein 0.0028 0.0113 0.0163
Loa Loa (eye worm) hypothetical protein 0.0036 0.0165 0.0243
Brugia malayi steroid hormone receptor 0.0027 0.011 0.0159
Schistosoma mansoni tubulin subunit alpha 0.0269 0.164 0.1929
Trichomonas vaginalis PIKK family atypical protein kinase 0.0026 0.0104 0.0137
Trichomonas vaginalis CMGC family protein kinase 0.01 0.057 0.0837
Schistosoma mansoni hypothetical protein 0.0059 0.0308 0.0362
Echinococcus multilocularis smad 0.0016 0.0039 0.0035
Echinococcus multilocularis JmjC domain containing protein 4 0.0015 0.0034 0.003
Plasmodium vivax tubulin alpha chain, putative 0.0807 0.5039 0.756
Onchocerca volvulus 0.0055 0.0287 0.1349
Loa Loa (eye worm) nuclear hormone receptor family member nhr-40 0.0027 0.011 0.0159
Schistosoma mansoni nuclear hormone receptor nor-1/nor-2 0.0027 0.011 0.0129
Brugia malayi hypothetical protein 0.023 0.1393 0.2086
Echinococcus granulosus ATP binding cassette subfamily B MDR:TAP 0.0021 0.007 0.0077
Schistosoma mansoni hypothetical protein 0.004 0.0188 0.0222
Echinococcus multilocularis cytoplasmic intermediate filament protein 0.0013 0.0018 0.0014
Schistosoma mansoni alpha tubulin 0.0807 0.5039 0.5928
Trypanosoma cruzi MFS transporter, putative 0.0055 0.0287 0.0424
Leishmania major alpha tubulin 0.0807 0.5039 0.7558
Trypanosoma cruzi PAS-domain containing phosphoglycerate kinase, putative 0.0025 0.0095 0.0136
Schistosoma mansoni multidrug resistance protein 0.0021 0.007 0.0082
Loa Loa (eye worm) hypothetical protein 0.0021 0.007 0.0099
Plasmodium vivax ataxin-2 like protein, putative 0.0049 0.0251 0.0376
Entamoeba histolytica P-glycoprotein-2 0.0021 0.007 0.0105
Echinococcus granulosus phosphatidylinositol 3 and 4 kinase 0.0015 0.0032 0.0033
Brugia malayi hypothetical protein 0.0055 0.0287 0.0424
Plasmodium falciparum ADP-dependent DNA helicase RecQ 0.0019 0.006 0.0038
Trichomonas vaginalis PIKK family atypical protein kinase 0.0024 0.0089 0.0114
Trichomonas vaginalis PIKK family atypical protein kinase 0.0044 0.0219 0.0309
Trypanosoma brucei epsilon tubulin 0.0622 0.3871 0.5805
Schistosoma mansoni mixed-lineage leukemia protein mll 0.006 0.032 0.0376
Echinococcus multilocularis neuropeptide s receptor 0.0452 0.2794 0.2791
Loa Loa (eye worm) hypothetical protein 0.0027 0.011 0.0159
Brugia malayi nuclear receptor NHR-88 0.0027 0.011 0.0159
Brugia malayi Tubulin beta chain 0.0327 0.2003 0.3
Onchocerca volvulus Netrin receptor homolog 0.0014 0.0026 0.0037
Loa Loa (eye worm) DR-78 0.0013 0.0019 0.0023
Leishmania major mitogen activated protein kinase, putative,map kinase, putative 0.01 0.057 0.085
Plasmodium vivax tubulin beta chain, putative 0.1064 0.6665 1
Loa Loa (eye worm) MH2 domain-containing protein 0.0234 0.1419 0.2125
Echinococcus granulosus geminin 0.0333 0.204 0.2397
Echinococcus multilocularis FTZ F1 nuclear receptor protein 0.0027 0.011 0.0106
Chlamydia trachomatis two component regulatory system sensor histidine kinase 0.0025 0.0095 1
Onchocerca volvulus 0.0038 0.0176 0.0791
Giardia lamblia Alpha-tubulin 0.0807 0.5039 0.7545
Echinococcus multilocularis Basic leucine zipper (bZIP) transcription 0.0071 0.0384 0.0381
Loa Loa (eye worm) tubulin alpha 2 0.0538 0.3337 0.5004
Mycobacterium tuberculosis Probable soluble pyridine nucleotide transhydrogenase SthA (STH) (NAD(P)(+) transhydrogenase [B-specific]) (nicotinamide nucleot 0.0016 0.004 0.0223
Plasmodium vivax thioredoxin reductase, putative 0.0047 0.0234 0.035
Plasmodium vivax tubulin alpha chain, putative 0.0807 0.5039 0.756
Leishmania major dihydrolipoamide dehydrogenase, putative 0.0016 0.004 0.0055
Trypanosoma brucei beta tubulin 0.1064 0.6665 1
Trypanosoma cruzi JmjC domain, hydroxylase, putative 0.0015 0.0034 0.0046
Brugia malayi photoreceptor-specific nuclear receptor 0.0027 0.011 0.0159
Echinococcus granulosus Smad4 0.0016 0.0039 0.0041
Trypanosoma cruzi phosphatidylinositol 3-related kinase, putative 0.0015 0.0032 0.0042
Echinococcus multilocularis lysine specific demethylase 5A 0.0057 0.03 0.0296
Onchocerca volvulus 0.0021 0.007 0.0256
Leishmania major beta tubulin 0.1064 0.6665 1
Plasmodium falciparum tubulin beta chain 0.1064 0.6665 1
Trichomonas vaginalis PIKK family atypical protein kinase 0.0024 0.009 0.0115
Entamoeba histolytica tyrosyl-DNA phosphodiesterase, putative 0.0064 0.0344 0.0516
Trichomonas vaginalis tubulin beta chain, putative 0.1064 0.6665 1
Trypanosoma brucei tubulin delta chain 0.0434 0.2683 0.4022
Echinococcus granulosus Nuclear hormone receptor family member nhr 41 0.0027 0.011 0.0125
Trichomonas vaginalis PIKK family atypical protein kinase 0.0026 0.0104 0.0137
Echinococcus granulosus Tubulin alpha 1 chain 0.0807 0.5039 0.5926
Brugia malayi Pax transcription factor protein 2 0.0234 0.1419 0.2124
Trichomonas vaginalis ATP-binding cassette transporter, putative 0.0021 0.007 0.0085
Schistosoma mansoni tubulin subunit alpha 0.0807 0.5039 0.5928
Schistosoma mansoni loxhd1 0.0059 0.0308 0.0362
Echinococcus multilocularis FTZ F1 alpha 0.0027 0.011 0.0106
Toxoplasma gondii thioredoxin reductase 0.0047 0.0234 0.035
Leishmania major phosphatidylinositol 3-related kinase, putative 0.0015 0.0032 0.0042
Echinococcus multilocularis isocitrate dehydrogenase 2 (NADP+) 0.0015 0.0035 0.0031
Trypanosoma brucei target of rapamycin kinase 3, putative 0.0035 0.0162 0.0237
Echinococcus multilocularis Polycystic kidney disease protein 0.0059 0.0308 0.0304
Toxoplasma gondii histone lysine methyltransferase SET1 0.0054 0.028 0.0419
Loa Loa (eye worm) nuclear hormone receptor 0.0013 0.0019 0.0023
Loa Loa (eye worm) tyrosyl-DNA phosphodiesterase 0.0064 0.0344 0.0511
Schistosoma mansoni RAR-like nuclear receptor 0.0027 0.011 0.0129
Trypanosoma brucei beta tubulin 0.1064 0.6665 1
Trichomonas vaginalis tubulin beta chain, putative 0.0327 0.2003 0.2991
Schistosoma mansoni ankyrin 23/unc44 0.0014 0.0026 0.0031
Trichomonas vaginalis PIKK family atypical protein kinase 0.0033 0.0147 0.0201
Schistosoma mansoni transcription factor LCR-F1 0.0071 0.0384 0.0452
Onchocerca volvulus 0.0327 0.2003 1
Loa Loa (eye worm) nuclear hormone receptor family member nhr-14 0.0027 0.011 0.0159
Trypanosoma cruzi trypanothione reductase, putative 0.0047 0.0234 0.0345
Brugia malayi hypothetical protein 0.0032 0.014 0.0204
Schistosoma mansoni phd/f-box containing protein 0.0015 0.0034 0.004
Trypanosoma cruzi zeta tubulin, putative 0.0545 0.3384 0.5075
Onchocerca volvulus Huntingtin homolog 0.0119 0.0692 0.3392
Schistosoma mansoni tubulin subunit beta 0.1064 0.6665 0.7841
Schistosoma mansoni nuclear hormone receptor 0.0013 0.0019 0.0022
Schistosoma mansoni aryl hydrocarbon receptor 0.0096 0.0541 0.0637
Brugia malayi Death domain containing protein 0.0014 0.0026 0.0034
Loa Loa (eye worm) hypothetical protein 0.0013 0.0019 0.0023
Loa Loa (eye worm) pre-SET domain-containing protein family protein 0.0207 0.1243 0.1861
Echinococcus multilocularis Transcription factor, JmjC domain containing protein 0.0057 0.03 0.0296
Echinococcus granulosus multidrug resistance protein 1 0.0015 0.003 0.0031
Echinococcus granulosus 5'partial|histone lysine N methyltransferase SETDB2 0.0028 0.0118 0.0134
Loa Loa (eye worm) hypothetical protein 0.0013 0.0019 0.0023
Echinococcus granulosus beta tubulin 0.1064 0.6665 0.784
Onchocerca volvulus 0.003 0.0128 0.0551
Schistosoma mansoni tubulin subunit beta 0.1064 0.6665 0.7841
Leishmania major alpha tubulin 0.0807 0.5039 0.7558
Echinococcus granulosus ubiquitin specific protease 41 0.0036 0.0165 0.019
Loa Loa (eye worm) phosphatidylinositol 3 0.0015 0.0032 0.0042
Trypanosoma cruzi STE group serine/threonine-protein kinase, putative 0.0026 0.01 0.0145
Trypanosoma cruzi tubulin delta chain 0.0434 0.2683 0.4022
Schistosoma mansoni DNA helicase recq1 0.0019 0.006 0.007
Echinococcus granulosus tubulin gamma 1 chain 0.0623 0.3873 0.4554
Trichomonas vaginalis PIKK family atypical protein kinase 0.0015 0.0032 0.0028
Trichomonas vaginalis tubulin gamma chain, putative 0.1064 0.6665 1
Schistosoma mansoni histone-lysine n-methyltransferase setb1 0.003 0.0128 0.0151
Brugia malayi Protein kinase domain containing protein 0.0015 0.0032 0.0042
Leishmania major acetoin dehydrogenase e3 component-like protein 0.0016 0.004 0.0055
Leishmania major beta tubulin 0.1064 0.6665 1
Trypanosoma cruzi JmjC domain, hydroxylase, putative 0.0015 0.0034 0.0046
Brugia malayi Isocitrate dehydrogenase 0.0015 0.0035 0.0047
Trichomonas vaginalis lipid A export ATP-binding/permease protein msba, putative 0.0021 0.007 0.0085
Echinococcus multilocularis tubulin alpha chain 0.0807 0.5039 0.5037
Plasmodium falciparum alpha tubulin 1 0.0807 0.5039 0.7547
Plasmodium falciparum isocitrate dehydrogenase [NADP], mitochondrial 0.0015 0.0035 0.0001
Echinococcus multilocularis tubulin gamma 1 chain 0.0623 0.3873 0.3871
Brugia malayi MH1 domain containing protein 0.0016 0.0039 0.0052
Brugia malayi hypothetical protein 0.0055 0.0287 0.0424
Brugia malayi multidrug resistance protein 3 0.0021 0.007 0.0099
Echinococcus granulosus Aryl hydrocarbon receptor nuclear 0.0025 0.0095 0.0107
Trichomonas vaginalis PIKK family atypical protein kinase 0.0024 0.009 0.0115
Schistosoma mansoni hypothetical protein 0.0022 0.0078 0.0092
Toxoplasma gondii ATP-binding cassette transporter ABC.B1 0.0021 0.007 0.0105
Plasmodium falciparum alpha tubulin 2 0.0807 0.5039 0.7547
Loa Loa (eye worm) hypothetical protein 0.0021 0.007 0.0099
Brugia malayi alpha keto acid dehydrogenase complex, E3 component, lipoamide dehydrogenase 0.0012 0.0013 0.0014
Brugia malayi jmjC domain containing protein 0.0015 0.0034 0.0046
Echinococcus multilocularis Nuclear hormone receptor HR96 0.0013 0.0019 0.0015
Brugia malayi nuclear receptor NHR-88 0.0013 0.0019 0.0023
Echinococcus granulosus lamin dm0 0.0026 0.0104 0.0118
Schistosoma mansoni ecdysone-induced protein 78c (dr-78) 0.0014 0.0029 0.0034
Trypanosoma cruzi epsilon tubulin, putative 0.0622 0.3871 0.5805
Echinococcus multilocularis mothers against decapentaplegic 5 0.0016 0.0039 0.0035
Onchocerca volvulus Putative organic anion transporter 0.0055 0.0287 0.1349
Schistosoma mansoni FTZ-F1 nuclear receptor-like protein 0.0027 0.011 0.0129
Schistosoma mansoni rab6-interacting 0.0059 0.0308 0.0362
Loa Loa (eye worm) hypothetical protein 0.0038 0.0176 0.0258
Entamoeba histolytica phosphatidylinositol3-kinaseTor2, putative 0.0044 0.0219 0.0328
Brugia malayi prostaglandin transporter 0.0055 0.0287 0.0424
Brugia malayi Tubulin alpha chain 0.0269 0.164 0.2456
Loa Loa (eye worm) nuclear receptor nhr-7B 0.0013 0.0019 0.0023
Echinococcus granulosus dihydrolipoamide dehydrogenase 0.0016 0.004 0.0043
Plasmodium falciparum tubulin epsilon chain, putative 0.0622 0.3871 0.5786
Loa Loa (eye worm) jmjC domain-containing protein 0.0059 0.031 0.0459
Chlamydia trachomatis ABC transporter ATP binding protein/permease 0.0021 0.007 0.5405
Schistosoma mansoni lipoxygenase 0.0226 0.1366 0.1607
Plasmodium vivax JmjC domain containing protein 0.0015 0.0034 0.0052
Leishmania major 2-oxoglutarate dehydrogenase, e3 component, lipoamidedehydrogenase-like protein 0.0016 0.004 0.0055
Brugia malayi nuclear hormone receptor 0.0013 0.0019 0.0023
Echinococcus granulosus multidrug resistance protein 1 0.0021 0.007 0.0077
Echinococcus multilocularis microtubule associated protein 2 0.1355 0.8501 0.85
Trichomonas vaginalis abcb9, putative 0.0021 0.007 0.0085
Trypanosoma cruzi mitogen activated protein kinase 2, putative 0.01 0.057 0.085
Echinococcus multilocularis ankyrin repeat and death domain containing protein 0.0014 0.0026 0.0022
Schistosoma mansoni hypothetical protein 0.0333 0.204 0.24
Onchocerca volvulus 0.0097 0.0552 0.2685
Echinococcus granulosus lipoxygenase domain containing protein 0.0059 0.0308 0.0358
Leishmania major ATP-dependent DEAD/H DNA helicase recQ, putative 0.0019 0.006 0.0084
Plasmodium vivax dihydrolipoyl dehydrogenase, apicoplast, putative 0.0016 0.004 0.006
Echinococcus granulosus tyrosyl DNA phosphodiesterase 1 0.0064 0.0344 0.04
Echinococcus granulosus nuclear receptor subfamily 4 group A 0.0013 0.0019 0.0018
Echinococcus granulosus jumonji domain containing 1A 0.0015 0.0034 0.0036
Loa Loa (eye worm) hypothetical protein 0.0059 0.0308 0.0456
Trichomonas vaginalis set domain proteins, putative 0.0235 0.1423 0.2119
Trypanosoma brucei isocitrate dehydrogenase, putative 0.0015 0.0035 0.0047
Echinococcus multilocularis ATP binding cassette subfamily B (MDR:TAP) 0.0021 0.007 0.0066
Loa Loa (eye worm) tubulin alpha-2 chain 0.0807 0.5039 0.7558
Loa Loa (eye worm) alpha-tubulin 0.0807 0.5039 0.7558
Brugia malayi hypothetical protein 0.032 0.1963 0.2941
Trichomonas vaginalis PIKK family atypical protein kinase 0.0044 0.0219 0.0309
Echinococcus multilocularis netrin receptor unc 5 0.0014 0.0026 0.0022
Toxoplasma gondii isocitrate dehydrogenase 0.0015 0.0035 0.0053
Trichomonas vaginalis PIKK family atypical protein kinase 0.0015 0.0032 0.0028
Giardia lamblia Gamma tubulin 0.0623 0.3873 0.5786
Brugia malayi hypothetical protein 0.0071 0.0384 0.0571
Echinococcus granulosus Tubulin beta 2C chain 0.1064 0.6665 0.784
Brugia malayi alpha-tubulin 0.0807 0.5039 0.7558
Brugia malayi hypothetical protein 0.0059 0.0308 0.0456
Loa Loa (eye worm) hypothetical protein 0.0055 0.0287 0.0424
Trypanosoma cruzi dihydrolipoamide dehydrogenase, putative 0.0016 0.004 0.0055
Echinococcus multilocularis NADP dependent isocitrate dehydrogenase 0.0015 0.0035 0.0031
Trichomonas vaginalis multidrug resistance protein 1, 2, putative 0.0021 0.007 0.0085
Mycobacterium tuberculosis Probable reductase 0.0107 0.0612 0.372
Echinococcus multilocularis Niemann Pick C1 protein 0.0137 0.0804 0.08
Loa Loa (eye worm) hypothetical protein 0.0015 0.0034 0.0046
Echinococcus granulosus nuclear receptor 2DBD gamma 0.0013 0.0019 0.0018
Echinococcus multilocularis Basic leucine zipper (bZIP) transcription factor 0.0082 0.0455 0.0451
Giardia lamblia GTOR 0.0044 0.0219 0.027
Echinococcus multilocularis tubulin alpha 1C chain 0.0807 0.5039 0.5037
Brugia malayi nuclear hormone receptor 0.0027 0.011 0.0159
Plasmodium falciparum thioredoxin reductase 0.0047 0.0234 0.03
Loa Loa (eye worm) hypothetical protein 0.0027 0.011 0.0159
Trypanosoma brucei ATP-dependent DEAD/H DNA helicase recQ, putative 0.0019 0.006 0.0084
Onchocerca volvulus 0.0028 0.0115 0.0482
Loa Loa (eye worm) immunoglobulin I-set domain-containing protein 0.0014 0.0026 0.0034
Echinococcus multilocularis nuclear receptor 2DBD gamma 0.0027 0.011 0.0106
Giardia lamblia Alpha-tubulin 0.0807 0.5039 0.7545
Giardia lamblia Ubiquitin carboxyl-terminal hydrolase 4 0.0036 0.0165 0.0189
Leishmania major beta tubulin 0.1064 0.6665 1
Trichomonas vaginalis PIKK family atypical protein kinase 0.0027 0.0106 0.0139
Mycobacterium leprae PROBABLE NADH DEHYDROGENASE NDH 0.0107 0.0612 0.372
Loa Loa (eye worm) alpha-tubulin isotype 2 0.0538 0.3337 0.5004
Echinococcus multilocularis multidrug resistance protein 1 0.0021 0.007 0.0066
Giardia lamblia Epsilon tubulin 0.0296 0.1806 0.2665
Onchocerca volvulus 0.0059 0.0308 0.1456
Echinococcus multilocularis expressed protein 0.0038 0.0176 0.0172
Onchocerca volvulus Putative organic anion transporter 0.0055 0.0287 0.1349
Giardia lamblia Beta tubulin 0.1064 0.6665 1
Trichomonas vaginalis tubulin gamma chain, putative 0.0623 0.3873 0.5803
Loa Loa (eye worm) hypothetical protein 0.048 0.2974 0.4459
Schistosoma mansoni phosphatidylinositol 3-and 4-kinase 0.0015 0.0032 0.0038
Schistosoma mansoni tubulin subunit beta 0.1064 0.6665 0.7841
Trichomonas vaginalis lipid A export ATP-binding/permease protein msba, putative 0.0021 0.007 0.0085
Echinococcus granulosus beta tubulin 0.1064 0.6665 0.784
Trypanosoma brucei JmjC domain, hydroxylase, putative 0.0015 0.0034 0.0046
Trichomonas vaginalis tubulin alpha chain, putative 0.0327 0.2003 0.2991
Loa Loa (eye worm) hypothetical protein 0.0055 0.0287 0.0424
Trichomonas vaginalis PIKK family atypical protein kinase 0.0024 0.0089 0.0114
Brugia malayi bHLH-PAS transcription factor 0.0071 0.0385 0.0572
Loa Loa (eye worm) MH1 domain-containing protein 0.0016 0.0039 0.0052
Onchocerca volvulus Protein ultraspiracle homolog 0.0027 0.011 0.0458
Brugia malayi Tubulin alpha-2 chain 0.0807 0.5039 0.7558
Brugia malayi sodium-independent organic anion transporter family protein 0.0055 0.0287 0.0424
Schistosoma mansoni cpg binding protein 0.003 0.0125 0.0147
Brugia malayi MAP kinase sur-1 0.01 0.057 0.085
Trichomonas vaginalis ABC transporter, half transporter, putative 0.0021 0.007 0.0085
Brugia malayi Niemann-Pick C1 protein precursor 0.0096 0.0544 0.081
Entamoeba histolytica hypothetical protein 0.0071 0.0384 0.0576
Onchocerca volvulus 0.0055 0.0287 0.1349
Trichomonas vaginalis PIKK family atypical protein kinase 0.0024 0.009 0.0115
Echinococcus granulosus tubulin alpha 3 chain 0.0807 0.5039 0.5926
Toxoplasma gondii beta-tubulin, putative 0.1064 0.6665 1
Trichomonas vaginalis adenylate and guanylate cyclases, putative 0.0025 0.0095 0.0122
Echinococcus multilocularis nuclear receptor 2DBD gamma 0.0013 0.0019 0.0015
Loa Loa (eye worm) CMGC/MAPK/ERK1 protein kinase 0.01 0.057 0.085
Brugia malayi nuclear receptor subfamily 1, group D, member 1, putative 0.0013 0.0019 0.0023
Echinococcus multilocularis phosphatidylinositol 3 and 4 kinase 0.0015 0.0032 0.0028
Brugia malayi cytoplasmic intermediate filament protein 0.0014 0.0027 0.0034
Entamoeba histolytica tubulin alpha chain, putative 0.0807 0.5039 0.756
Trypanosoma brucei protein kinase, putative 0.01 0.057 0.085
Schistosoma mansoni survival motor neuron protein 0.0047 0.0235 0.0276
Brugia malayi tailless protein 0.0013 0.0019 0.0023
Schistosoma mansoni photoreceptor-specific nuclear receptor related 0.0027 0.011 0.0129
Trypanosoma cruzi tyrosyl-DNA Phosphodiesterase (Tdp1), putative 0.0064 0.0344 0.0511
Trichomonas vaginalis tubulin alpha chain, putative 0.0327 0.2003 0.2991
Brugia malayi Tubulin beta chain 0.0269 0.164 0.2456
Mycobacterium tuberculosis Probable membrane NADH dehydrogenase NdhA 0.0107 0.0612 0.372
Trypanosoma cruzi cytochrome P450, putative 0.0028 0.0113 0.0163
Loa Loa (eye worm) hypothetical protein 0.0097 0.0552 0.0822
Brugia malayi Bloom's syndrome protein homolog 0.0019 0.006 0.0084
Brugia malayi PAS domain containing protein 0.0096 0.0541 0.0807
Trichomonas vaginalis CMGC family protein kinase 0.01 0.057 0.0837
Schistosoma mansoni jumonji domain containing protein 0.0057 0.03 0.0353
Brugia malayi Thioredoxin reductase 0.0047 0.0234 0.0345
Schistosoma mansoni jumonji/arid domain-containing protein 0.0059 0.031 0.0365
Echinococcus multilocularis Niemann Pick C1 protein 0.0096 0.0544 0.054
Schistosoma mansoni smad1 5 8 and 0.0016 0.0039 0.0046
Entamoeba histolytica tubulin alpha-1 chain 0.0807 0.5039 0.756
Leishmania major trypanothione reductase 0.0047 0.0234 0.0345
Plasmodium vivax multidrug resistance protein 1, putative 0.0021 0.007 0.0105
Echinococcus multilocularis hepatocyte nuclear factor 4 alpha 0.0027 0.011 0.0106
Trypanosoma brucei ubiquitin carboxyl-terminal hydrolase, putative 0.0036 0.0165 0.0243
Echinococcus multilocularis Tubulin beta 2C chain 0.1064 0.6665 0.6664
Echinococcus granulosus TGF beta signal transducer SmadC 0.0016 0.0039 0.0041
Brugia malayi Nuclear hormone receptor family member nhr-49 0.0027 0.011 0.0159
Brugia malayi hypothetical protein 0.0064 0.0344 0.051
Loa Loa (eye worm) hypothetical protein 0.0013 0.0018 0.0021
Loa Loa (eye worm) hypothetical protein 0.0119 0.0692 0.1033
Echinococcus granulosus 5'partial|ATP binding cassette sub family B 0.0021 0.0068 0.0076
Mycobacterium tuberculosis Probable nitrite reductase [NAD(P)H] large subunit [FAD flavoprotein] NirB 0.0107 0.0612 0.372
Plasmodium falciparum dihydrolipoyl dehydrogenase, mitochondrial 0.0016 0.004 0.0009
Echinococcus multilocularis lipoxygenase domain containing protein 0.0059 0.0308 0.0304
Schistosoma mansoni retinoic acid receptor RXR 0.0027 0.011 0.0129
Loa Loa (eye worm) tubulin alpha-3 chain 0.048 0.2974 0.4459
Echinococcus multilocularis aryl hydrocarbon receptor 0.0025 0.0095 0.0091
Loa Loa (eye worm) hypothetical protein 0.0014 0.0026 0.0034
Loa Loa (eye worm) hypothetical protein 0.008 0.0441 0.0655
Trichomonas vaginalis tubulin beta chain, putative 0.0807 0.5039 0.7555
Echinococcus granulosus ATP dependent DNA helicase Q1 0.0019 0.006 0.0066
Loa Loa (eye worm) hypothetical protein 0.0013 0.0019 0.0023
Brugia malayi Nuclear hormone receptor family member nhr-19 0.0027 0.011 0.0159
Brugia malayi sodium-independent organic anion transporter family protein 0.0055 0.0287 0.0424
Trypanosoma cruzi isocitrate dehydrogenase, putative 0.0015 0.0035 0.0047
Echinococcus granulosus arachidonate 5 lipoxygenase 0.0226 0.1366 0.1603
Plasmodium falciparum glutathione reductase 0.0047 0.0234 0.03
Toxoplasma gondii cytochrome p450 superfamily protein 0.001 0.0004 0.0006
Echinococcus granulosus nuclear receptor subfamily 1 group D 0.0014 0.0029 0.0029
Trichomonas vaginalis multidrug resistance protein 1, 2, putative 0.0021 0.007 0.0085
Brugia malayi CHE-14 protein 0.0041 0.0198 0.0291
Echinococcus multilocularis expressed conserved protein 0.009 0.0507 0.0503
Echinococcus multilocularis NADP dependent isocitrate dehydrogenase 0.0015 0.0035 0.0031
Trypanosoma cruzi cytochrome P450, putative 0.0028 0.0113 0.0163
Entamoeba histolytica Niemann-Pick C1 protein, putative 0.0096 0.0544 0.0816
Trypanosoma cruzi epsilon tubulin, putative 0.0622 0.3871 0.5805
Brugia malayi ABC transporter family protein 0.0021 0.007 0.0099
Leishmania major alpha tubulin 0.0807 0.5039 0.7558
Echinococcus granulosus Ankyrin 0.0014 0.0027 0.0027
Brugia malayi nuclear hormone receptor family member odr-7 0.0013 0.0019 0.0023
Loa Loa (eye worm) jmjC domain-containing protein 0.0015 0.0034 0.0046
Echinococcus granulosus neuropeptide s receptor 0.0452 0.2794 0.3284
Brugia malayi Tubulin beta-1 chain 0.1064 0.6665 1
Trichomonas vaginalis tubulin, putative 0.0327 0.2003 0.2991
Trypanosoma cruzi alpha tubulin, putative 0.0807 0.5039 0.7558
Loa Loa (eye worm) hypothetical protein 0.0059 0.0308 0.0456
Schistosoma mansoni tubulin subunit beta 0.1064 0.6665 0.7841
Leishmania major ATP-binding cassette protein subfamily B, member 2, putative 0.0021 0.007 0.0099
Schistosoma mansoni hypothetical protein 0.004 0.0188 0.0222
Trichomonas vaginalis ABC transporter, putative 0.0021 0.007 0.0085
Schistosoma mansoni organic anion transporter 0.0055 0.0287 0.0337
Schistosoma mansoni retinoid-x-receptor (RXR) 0.0014 0.0029 0.0034
Brugia malayi nuclear hormone receptor family member nhr-6 0.0013 0.0019 0.0023
Brugia malayi Tubulin gamma chain 0.0623 0.3873 0.5809
Loa Loa (eye worm) hypothetical protein 0.0807 0.5039 0.7558
Echinococcus multilocularis TGF beta signal transducer SmadC 0.0016 0.0039 0.0035
Trichomonas vaginalis conserved hypothetical protein 0.0025 0.0095 0.0122
Brugia malayi MH2 domain containing protein 0.0234 0.1419 0.2125
Loa Loa (eye worm) hypothetical protein 0.023 0.1393 0.2086
Echinococcus multilocularis hypothetical protein 0.0807 0.5039 0.5037
Echinococcus granulosus Tubulin alpha 1 chain 0.0807 0.5039 0.5926
Toxoplasma gondii tubulin/FtsZ family, GTPase domain-containing protein 0.0596 0.3704 0.5558
Entamoeba histolytica P-glyco protein 6, putative 0.0021 0.007 0.0105
Mycobacterium tuberculosis Putative ferredoxin reductase 0.0107 0.0612 0.372
Echinococcus granulosus survival motor neuron protein 1 0.023 0.1393 0.1635
Leishmania major alpha tubulin 0.0807 0.5039 0.7558
Schistosoma mansoni Tr4/Tr2 (homologue) 0.0027 0.011 0.0129
Schistosoma mansoni dihydrolipoamide dehydrogenase 0.0016 0.004 0.0047
Trichomonas vaginalis tubulin alpha-1 chain, putative 0.0538 0.3337 0.4997
Brugia malayi SPARC precursor 0.0038 0.0176 0.0258
Trichomonas vaginalis lipid A export ATP-binding/permease protein msba, putative 0.0021 0.007 0.0085
Echinococcus granulosus bloom syndrome protein 0.0019 0.006 0.0066
Echinococcus multilocularis lipoxygenase domain containing protein 0.0059 0.0308 0.0304
Loa Loa (eye worm) hypothetical protein 0.0055 0.0287 0.0424
Schistosoma mansoni protein phosphatase 2C 0.0015 0.0034 0.004
Echinococcus granulosus single minded 2 0.0071 0.0385 0.0448
Brugia malayi Phosphatidylinositol 3- and 4-kinase family protein 0.0044 0.0219 0.0323
Echinococcus granulosus JmjC domain containing protein 4 0.0015 0.0034 0.0036
Loa Loa (eye worm) nuclear hormone receptor family member nhr-41 0.0027 0.011 0.0159
Loa Loa (eye worm) hypothetical protein 0.032 0.1963 0.2941
Brugia malayi Nuclear hormone receptor family member nhr-41 0.0027 0.011 0.0159
Plasmodium falciparum tubulin delta chain, putative 0.0269 0.164 0.2421
Schistosoma mansoni hypothetical protein 0.0047 0.0235 0.0276
Toxoplasma gondii Kazal-type serine protease inhibitor domain-containing protein 0.0038 0.0176 0.0264
Trichomonas vaginalis lipid A export ATP-binding/permease protein msba, putative 0.0021 0.007 0.0085
Schistosoma mansoni tubulin subunit delta 0.0269 0.164 0.1929
Echinococcus multilocularis Peptidase C19, ubiquitin carboxyl terminal hydrolase 2 0.0036 0.0165 0.0162
Echinococcus multilocularis dihydrolipoamide dehydrogenase 0.0016 0.004 0.0036
Loa Loa (eye worm) follicle stimulating hormone receptor 0.0231 0.1401 0.2097
Trypanosoma brucei phosphatidylinositol 3-related kinase, putative 0.0015 0.0032 0.0042
Echinococcus granulosus multidrug resistance protein 1 0.0021 0.007 0.0077
Onchocerca volvulus 0.0027 0.011 0.0458
Leishmania major hypothetical protein, conserved 0.0049 0.0251 0.037
Brugia malayi Smad1 0.0016 0.0039 0.0052
Leishmania major beta tubulin 0.1064 0.6665 1
Trichomonas vaginalis ABC transporter, putative 0.0021 0.007 0.0085
Schistosoma mansoni cpg binding protein 0.003 0.0125 0.0147
Echinococcus granulosus FTZ F1 nuclear receptor protein 0.0027 0.011 0.0125
Trichomonas vaginalis mercuric reductase, putative 0.0016 0.004 0.0041
Brugia malayi Nuclear hormone receptor family member nhr-25 0.0027 0.011 0.0159
Schistosoma mansoni polycystin 1-related 0.0059 0.0308 0.0362
Trichomonas vaginalis tubulin epsilon chain, putative 0.1064 0.6665 1
Brugia malayi Cell division protein ftsZ 0.0269 0.164 0.2456
Mycobacterium tuberculosis Probable isocitrate dehydrogenase [NADP] Icd1 (oxalosuccinate decarboxylase) (IDH) (NADP+-specific ICDH) (IDP) 0.0015 0.0035 0.0191
Entamoeba histolytica hypothetical protein 0.0071 0.0384 0.0576
Toxoplasma gondii alpha tubulin TUBA1 0.0807 0.5039 0.756
Echinococcus multilocularis Aryl hydrocarbon receptor nuclear 0.0025 0.0095 0.0091
Toxoplasma gondii tubulin/FtsZ family, GTPase domain-containing protein 0.0434 0.2683 0.4026
Brugia malayi Nuclear hormone receptor-like 1 0.0014 0.0029 0.0037
Brugia malayi Iron-sulfur cluster assembly accessory protein 0.0047 0.0235 0.0346
Toxoplasma gondii beta tubulin 0.1064 0.6665 1
Entamoeba histolytica tubulin gamma chain 0.0623 0.3873 0.5811
Echinococcus granulosus tubulin alpha chain 0.0807 0.5039 0.5926
Plasmodium vivax tubulin epsilon chain, putative 0.0622 0.3871 0.5807
Echinococcus granulosus FKBP12 rapamycin complex associated protein 0.0044 0.0219 0.0253
Loa Loa (eye worm) intermediate filament protein 0.0026 0.0104 0.015
Echinococcus multilocularis nuclear receptor subfamily 1 group D 0.0014 0.0029 0.0025
Loa Loa (eye worm) hypothetical protein 0.0055 0.0287 0.0424
Loa Loa (eye worm) cytoplasmic intermediate filament protein 0.0014 0.0027 0.0034
Brugia malayi Doublecortin family protein 0.0059 0.0308 0.0456
Loa Loa (eye worm) BEN-1 protein 0.1064 0.6665 1
Brugia malayi Pre-SET motif family protein 0.003 0.0128 0.0187
Trypanosoma brucei dihydrolipoyl dehydrogenase 0.0016 0.004 0.0055
Echinococcus granulosus Basic leucine zipper bZIP transcription 0.0071 0.0384 0.0448
Brugia malayi jmjC domain containing protein 0.0015 0.0034 0.0046
Echinococcus granulosus tubulin beta 4A class IVa 0.1064 0.6665 0.784
Brugia malayi Nuclear hormone receptor family member nhr-14 0.0027 0.011 0.0159
Leishmania major PAS-domain containing phosphoglycerate kinase, putative 0.0025 0.0095 0.0136
Plasmodium vivax multidomain scavenger receptor, putative 0.0059 0.0308 0.0462
Echinococcus multilocularis tubulin alpha 1C chain 0.0807 0.5039 0.5037
Trichomonas vaginalis tubulin epsilon chain, putative 0.0269 0.164 0.2445
Entamoeba histolytica hypothetical protein 0.0071 0.0384 0.0576
Echinococcus multilocularis tubulin epsilon chain 0.0622 0.3871 0.3869
Entamoeba histolytica P-glycoprotein-1 0.0021 0.007 0.0105
Brugia malayi Nuclear hormone receptor family member nhr-1 0.0027 0.011 0.0159
Echinococcus multilocularis geminin 0.0333 0.204 0.2037
Trypanosoma brucei epsilon tubulin 0.0596 0.3704 0.5555
Leishmania major mitogen activated protein kinase 4, putative;with=GeneDB:LmxM19.1440 0.01 0.057 0.085
Trypanosoma brucei FAT domain/Rapamycin binding domain/Phosphatidylinositol 3- and 4-kinase, putative 0.0018 0.0055 0.0076
Brugia malayi Uncoordinated protein 44 0.0014 0.0026 0.0034
Onchocerca volvulus Putative organic anion transporter 0.0055 0.0287 0.1349
Loa Loa (eye worm) hypothetical protein 0.0027 0.011 0.0159
Entamoeba histolytica FKBP-rapamycin associated protein (FRAP), putative 0.0044 0.0219 0.0328
Echinococcus granulosus Niemann Pick C1 protein 0.0137 0.0804 0.0941
Echinococcus granulosus tubulin subunit TubB 0.0807 0.5039 0.5926
Echinococcus multilocularis peroxisome assembly protein 26 0.0807 0.5039 0.5037
Loa Loa (eye worm) hypothetical protein 0.0017 0.0047 0.0064
Echinococcus granulosus mitogen activated protein kinase 0.01 0.057 0.0666
Loa Loa (eye worm) kazal-type serine protease inhibitor domain-containing protein 0.0038 0.0176 0.0258
Schistosoma mansoni smad 0.0016 0.0039 0.0046
Loa Loa (eye worm) hypothetical protein 0.0014 0.0029 0.0037
Leishmania major beta tubulin 0.1064 0.6665 1
Echinococcus multilocularis ATP binding cassette subfamily B (MDR:TAP) 0.0021 0.007 0.0066
Trypanosoma brucei phosphatidylinositol 3-kinase, putative 0.0015 0.0032 0.0042
Echinococcus granulosus Polycystic kidney disease protein 0.0059 0.0308 0.0358
Echinococcus multilocularis transcription factor Dp 1 0.0037 0.0173 0.0169
Trypanosoma brucei dihydrolipoamide dehydrogenase, point mutation 0.0016 0.004 0.0055
Echinococcus multilocularis phd:f box containing protein 0.0015 0.0034 0.003
Brugia malayi Kazal-type serine protease inhibitor domain containing protein 0.0038 0.0176 0.0258
Mycobacterium ulcerans dihydrolipoamide dehydrogenase 0.0016 0.004 0.0223
Loa Loa (eye worm) CXXC zinc finger family protein 0.0028 0.0115 0.0166
Schistosoma mansoni nuclear receptor 2DBD-gamma 0.0027 0.011 0.0129
Trichomonas vaginalis tubulin alpha chain, putative 0.1064 0.6665 1
Trypanosoma brucei alpha tubulin 0.0807 0.5039 0.7558
Echinococcus granulosus dnaJ subfamily B 0.0398 0.2455 0.2885
Trichomonas vaginalis PIKK family atypical protein kinase 0.0015 0.0032 0.0028
Trichomonas vaginalis tubulin alpha-1 chain, putative 0.0327 0.2003 0.2991
Leishmania major beta tubulin 0.1064 0.6665 1
Plasmodium vivax dihydrolipoyl dehydrogenase, mitochondrial, putative 0.0016 0.004 0.006
Trichomonas vaginalis PIKK family atypical protein kinase 0.0033 0.0147 0.0201
Onchocerca volvulus 0.0025 0.0095 0.0382
Echinococcus multilocularis Tubulin beta 2C chain 0.1064 0.6665 0.6664
Brugia malayi nuclear receptor RXR 0.0013 0.0019 0.0023
Schistosoma mansoni histone-lysine n-methyltransferase suv9 0.003 0.0128 0.0151
Echinococcus multilocularis tumor protein p63 0.0663 0.4131 0.4128
Trichomonas vaginalis lipid A export ATP-binding/permease protein msba, putative 0.0021 0.007 0.0085
Schistosoma mansoni tubulin subunit beta 0.1064 0.6665 0.7841
Schistosoma mansoni tubulin subunit beta 0.1064 0.6665 0.7841
Brugia malayi Nuclear hormone receptor family member nhr-3 0.0027 0.011 0.0159
Onchocerca volvulus 0.0055 0.0287 0.1349
Brugia malayi Intermediate filament tail domain containing protein 0.0026 0.0104 0.015
Echinococcus granulosus Nuclear hormone receptor HR96 0.0013 0.0019 0.0018
Echinococcus multilocularis jun protein 0.0082 0.0455 0.0451
Trichomonas vaginalis PIKK family atypical protein kinase 0.0035 0.0161 0.0223
Trichomonas vaginalis multidrug resistance protein 1, 2, putative 0.0021 0.007 0.0085
Leishmania major p-glycoprotein 0.0021 0.007 0.0099
Echinococcus granulosus tubulin alpha chain 0.0807 0.5039 0.5926
Schistosoma mansoni tubulin subunit beta 0.0269 0.164 0.1929
Echinococcus granulosus alpha tubulin 0.0807 0.5039 0.5926
Loa Loa (eye worm) hypothetical protein 0.0538 0.3337 0.5004
Entamoeba histolytica P-glycoprotein-2, putative 0.0021 0.007 0.0105
Loa Loa (eye worm) hypothetical protein 0.0038 0.0176 0.0258
Leishmania major alpha tubulin 0.0807 0.5039 0.7558
Schistosoma mansoni alpha tubulin 0.0807 0.5039 0.5928
Leishmania major beta tubulin 0.1064 0.6665 1
Schistosoma mansoni lamin 0.0026 0.0104 0.0122
Schistosoma mansoni niemann-pick C1 (NPC1) 0.0097 0.0553 0.0651
Onchocerca volvulus Bile acid receptor homolog 0.0027 0.011 0.0458
Loa Loa (eye worm) hypothetical protein 0.0013 0.0019 0.0023
Schistosoma mansoni hypothetical protein 0.004 0.0188 0.0222
Loa Loa (eye worm) nuclear hormone receptor-like 1 0.0014 0.0029 0.0037
Loa Loa (eye worm) hypothetical protein 0.0055 0.0287 0.0424
Brugia malayi Tubulin alpha chain 0.0807 0.5039 0.7558
Echinococcus multilocularis ATP binding cassette subfamily B (MDR:TAP) 0.0021 0.007 0.0066
Echinococcus granulosus tubulin epsilon chain 0.0622 0.3871 0.4551
Echinococcus granulosus tubulin alpha 3 chain 0.0807 0.5039 0.5926
Echinococcus granulosus Tubulin beta 2C chain 0.1064 0.6665 0.784
Echinococcus granulosus retinoic acid receptor rxr beta a 0.0027 0.011 0.0125
Schistosoma mansoni serine/threonine protein kinase 0.01 0.057 0.0671
Loa Loa (eye worm) tubulin alpha 2 0.0211 0.1272 0.1904
Loa Loa (eye worm) isocitrate dehydrogenase 0.0015 0.0035 0.0047
Echinococcus granulosus Tubulin alpha 1 chain 0.0807 0.5039 0.5926
Toxoplasma gondii LsmAD domain-containing protein 0.0049 0.0251 0.0376
Echinococcus granulosus microtubule associated protein 2 0.1355 0.8501 1
Loa Loa (eye worm) tubulin beta-2A chain 0.1064 0.6665 1
Brugia malayi hypothetical protein 0.0119 0.0692 0.1033
Loa Loa (eye worm) hypothetical protein 0.0096 0.0544 0.081
Trichomonas vaginalis CMGC family protein kinase 0.01 0.057 0.0837
Loa Loa (eye worm) hypothetical protein 0.0013 0.0019 0.0023
Echinococcus multilocularis multidrug resistance protein 1 0.0021 0.007 0.0066
Loa Loa (eye worm) hypothetical protein 0.0027 0.011 0.0159
Leishmania major target of rapamycin (TOR) kinase 1, putative 0.0044 0.0219 0.0323
Loa Loa (eye worm) hypothetical protein 0.0027 0.011 0.0159
Schistosoma mansoni coup transcription factor 0.0027 0.011 0.0129
Trichomonas vaginalis PIKK family atypical protein kinase 0.0033 0.0147 0.0201
Trypanosoma brucei cytochrome P450, putative 0.0028 0.0113 0.0163
Echinococcus granulosus Basic leucine zipper bZIP transcription factor 0.0082 0.0455 0.0531
Loa Loa (eye worm) nuclear hormone receptor family member nhr-1 0.0027 0.011 0.0159
Giardia lamblia Beta tubulin 0.1064 0.6665 1
Schistosoma mansoni lamin 0.0026 0.0104 0.0122
Giardia lamblia Sgs1 DNA helicase, putative 0.0019 0.006 0.0029
Echinococcus granulosus Jumonji AT rich interactive domain 1B 0.0017 0.0044 0.0048
Brugia malayi glutathione reductase 0.0047 0.0234 0.0345
Trypanosoma cruzi mitogen-activated protein kinase 11, putative 0.01 0.057 0.085
Schistosoma mansoni nuclear hormone receptor superfamily protein-related 0.0013 0.0019 0.0022
Echinococcus granulosus tubulin beta 1 chain 0.1064 0.6665 0.784
Echinococcus multilocularis Jumonji, AT rich interactive domain 1B 0.0017 0.0044 0.0041
Loa Loa (eye worm) hypothetical protein 0.0041 0.0198 0.0291
Loa Loa (eye worm) hypothetical protein 0.0014 0.0029 0.0037
Echinococcus multilocularis tubulin delta chain 0.0269 0.164 0.1636
Echinococcus multilocularis tubulin subunit beta 0.1064 0.6665 0.6664
Trypanosoma brucei dihydrolipoamide dehydrogenase 0.0016 0.004 0.0055
Loa Loa (eye worm) sodium-independent organic anion transporter 0.0055 0.0287 0.0424
Echinococcus granulosus tubulin alpha chain 0.0807 0.5039 0.5926
Schistosoma mansoni steroid hormone receptor ad4bp 0.0027 0.011 0.0129
Trichomonas vaginalis tubulin beta chain, putative 0.0807 0.5039 0.7555
Loa Loa (eye worm) multidrug resistance protein 3 0.0021 0.007 0.0099
Schistosoma mansoni nuclear receptor nhr-48 0.0013 0.0019 0.0022
Schistosoma mansoni jumonji domain containing protein 0.0015 0.0034 0.004
Echinococcus multilocularis RUN 0.0059 0.0308 0.0304
Echinococcus multilocularis Ataxin 2, N terminal,domain containing protein 0.0022 0.0078 0.0074
Loa Loa (eye worm) hypothetical protein 0.0013 0.0019 0.0023
Plasmodium falciparum multidrug resistance protein 1 0.0021 0.007 0.0053
Loa Loa (eye worm) hypothetical protein 0.0012 0.0015 0.0017
Plasmodium vivax delta tubulin, putative 0.0269 0.164 0.246
Toxoplasma gondii histone lysine demethylase JMJD6a 0.0015 0.0034 0.0052
Echinococcus granulosus multidrug resistance protein 1 0.0021 0.007 0.0077
Echinococcus granulosus cytoplasmic intermediate filament protein 0.0013 0.0018 0.0017
Mycobacterium ulcerans dihydrolipoamide dehydrogenase, LpdB 0.0016 0.004 0.0223
Echinococcus multilocularis Ankyrin 0.0014 0.0027 0.0023
Echinococcus multilocularis ATP dependent DNA helicase Q5 0.0019 0.006 0.0056
Echinococcus granulosus COUP TF:Svp nuclear hormone receptor 0.0027 0.011 0.0125
Loa Loa (eye worm) phosphatidylinositol 3 0.0044 0.0219 0.0323
Echinococcus multilocularis ATP dependent DNA helicase Q1 0.0019 0.006 0.0056
Loa Loa (eye worm) hypothetical protein 0.0013 0.0019 0.0023
Toxoplasma gondii tubulin/FtsZ family, GTPase domain-containing protein 0.0296 0.1806 0.271
Echinococcus multilocularis tubulin alpha chain 0.0807 0.5039 0.5037
Schistosoma mansoni smdr2 0.0021 0.007 0.0082
Schistosoma mansoni Smad4 0.0016 0.0039 0.0046
Trichomonas vaginalis tubulin beta chain, putative 0.0807 0.5039 0.7555
Trypanosoma brucei mitogen activated protein kinase 4, putative 0.01 0.057 0.085
Echinococcus granulosus follistatin 0.0038 0.0176 0.0203
Trypanosoma brucei beta tubulin 0.1064 0.6665 1
Trichomonas vaginalis PIKK family atypical protein kinase 0.0033 0.0147 0.0201
Trypanosoma brucei dihydrolipoamide dehydrogenase 0.0016 0.004 0.0055
Echinococcus multilocularis Tubulin beta 2C chain 0.1064 0.6665 0.6664
Loa Loa (eye worm) intermediate filament tail domain-containing protein 0.0026 0.0104 0.015
Echinococcus granulosus Transcription factor JmjC domain containing protein 0.0057 0.03 0.0348
Loa Loa (eye worm) hypothetical protein 0.0013 0.0019 0.0023
Echinococcus multilocularis Tubulin alpha 1 chain 0.0807 0.5039 0.5037
Brugia malayi jmjC domain containing protein 0.0015 0.0034 0.0046
Loa Loa (eye worm) transcription factor SMAD2 0.0234 0.1419 0.2125
Leishmania major alpha tubulin 0.0807 0.5039 0.7558
Echinococcus multilocularis lamin dm0 0.0026 0.0104 0.01
Trichomonas vaginalis ATP-binding cassette transporter, putative 0.0021 0.007 0.0085
Plasmodium falciparum ATP-dependent DNA helicase Q1 0.0019 0.006 0.0038
Echinococcus multilocularis survival motor neuron protein 1 0.023 0.1393 0.139
Onchocerca volvulus 0.0071 0.0385 0.1843
Schistosoma mansoni hypothetical protein 0.0014 0.0026 0.0031
Trichomonas vaginalis PIKK family atypical protein kinase 0.0033 0.0147 0.0201
Toxoplasma gondii NADPH-glutathione reductase 0.0016 0.004 0.006
Echinococcus granulosus mothers against decapentaplegic 5 0.0016 0.0039 0.0041
Trichomonas vaginalis tubulin beta chain, putative 0.0807 0.5039 0.7555
Entamoeba histolytica P-glycoprotein-5 0.0021 0.007 0.0105
Toxoplasma gondii alpha-tubulin I, putative 0.0807 0.5039 0.756
Trypanosoma cruzi STE/STE11 serine/threonine-protein kinase, putative 0.0026 0.01 0.0145
Echinococcus multilocularis nuclear receptor subfamily 4 group A 0.0013 0.0019 0.0015
Schistosoma mansoni hypothetical protein 0.0398 0.2455 0.2888
Trichomonas vaginalis PIKK family atypical protein kinase 0.003 0.0126 0.017
Echinococcus granulosus tubulin subunit beta 0.1064 0.6665 0.784
Trichomonas vaginalis adenylate and guanylate cyclases, putative 0.0025 0.0095 0.0122
Echinococcus multilocularis tyrosyl DNA phosphodiesterase 1 0.0064 0.0344 0.034
Echinococcus multilocularis sterol regulatory element binding protein 0.0041 0.0198 0.0194
Brugia malayi MH2 domain containing protein 0.0016 0.0039 0.0052
Brugia malayi ATP-dependent DNA helicase, RecQ family protein 0.0019 0.006 0.0084
Trypanosoma brucei Phosphatidylinositol 3-kinase tor1 0.0044 0.0219 0.0323
Mycobacterium tuberculosis Probable NADH dehydrogenase Ndh 0.0107 0.0612 0.372
Wolbachia endosymbiont of Brugia malayi cell division protein FtsZ 0.0269 0.164 1
Loa Loa (eye worm) hypothetical protein 0.0013 0.0019 0.0023
Trypanosoma brucei PAB1-binding protein , putative 0.0049 0.0251 0.037
Plasmodium falciparum ataxin-2 like protein, putative 0.0049 0.0251 0.0326
Echinococcus granulosus nuclear receptor 2DBD gamma 0.0027 0.011 0.0125
Loa Loa (eye worm) tubulin alpha 2 0.0538 0.3337 0.5004
Schistosoma mansoni ubiquitin-specific peptidase 2 (C19 family) 0.0036 0.0165 0.0195
Echinococcus granulosus multidrug resistance protein 1 0.0015 0.003 0.0031
Echinococcus granulosus Nuclear hormone receptor HR96 0.0013 0.0019 0.0018
Trypanosoma brucei alpha tubulin 0.0807 0.5039 0.7558
Trypanosoma brucei epsilon tubulin 0.0622 0.3871 0.5805
Toxoplasma gondii isocitrate dehydrogenase 0.0015 0.0035 0.0053
Toxoplasma gondii ATP-dependent DNA helicase, RecQ family protein 0.0019 0.006 0.009
Echinococcus granulosus tubulin delta chain 0.0269 0.164 0.1925
Leishmania major tyrosyl-DNA phosphodiesterase 1 0.0064 0.0344 0.0511
Schistosoma mansoni cellular tumor antigen P53 0.0097 0.0552 0.0649
Loa Loa (eye worm) hypothetical protein 0.0014 0.0029 0.0037
Trichomonas vaginalis PIKK family atypical protein kinase 0.0024 0.0089 0.0114
Trichomonas vaginalis tubulin alpha chain, putative 0.0327 0.2003 0.2991
Giardia lamblia Beta tubulin 0.1064 0.6665 1
Echinococcus multilocularis thioredoxin glutathione reductase 0.0047 0.0234 0.023
Echinococcus granulosus ATP binding cassette subfamily B MDR:TAP 0.0021 0.007 0.0077
Brugia malayi hypoxia-induced factor 1 0.0296 0.1806 0.2705
Schistosoma mansoni smad1 5 8 and 0.0016 0.0039 0.0046
Loa Loa (eye worm) tubulin alpha chain 0.0807 0.5039 0.7558
Onchocerca volvulus 0.0026 0.0104 0.0428
Trichomonas vaginalis multidrug resistance protein 1, 2, putative 0.0021 0.007 0.0085
Echinococcus granulosus Ataxin 2 N terminaldomain containing protein 0.0022 0.0078 0.0087
Trypanosoma brucei trypanothione reductase 0.0047 0.0234 0.0345
Mycobacterium tuberculosis NAD(P)H quinone reductase LpdA 0.0119 0.0688 0.418
Trypanosoma cruzi dihydrolipoamide dehydrogenase, putative 0.0016 0.004 0.0055
Brugia malayi hypothetical protein 0.0013 0.0019 0.0023
Brugia malayi MH2 domain containing protein 0.0016 0.0039 0.0052
Toxoplasma gondii beta-1 tubulin, putative 0.1064 0.6665 1
Loa Loa (eye worm) agrin synaptic family protein 0.0038 0.0176 0.0258
Loa Loa (eye worm) tubulin beta-1 chain 0.1064 0.6665 1
Trichomonas vaginalis PIKK family atypical protein kinase 0.0035 0.0161 0.0223
Leishmania major zeta tubulin, putative 0.0545 0.3384 0.5075
Toxoplasma gondii tubulin, putative 0.0026 0.0104 0.0157
Onchocerca volvulus 0.0059 0.0308 0.1456
Loa Loa (eye worm) hypothetical protein 0.0014 0.0029 0.0037
Loa Loa (eye worm) nuclear receptor NHR-67 0.0013 0.0019 0.0023
Mycobacterium ulcerans cytochrome P450 185A4 Cyp185A4 0.0028 0.0113 0.0665
Echinococcus granulosus ATP binding cassette subfamily B MDR:TAP 0.0021 0.007 0.0077
Trichomonas vaginalis PIKK family atypical protein kinase 0.0027 0.0106 0.0139
Leishmania major alpha tubulin 0.0807 0.5039 0.7558
Schistosoma mansoni smad1 5 8 and 0.0016 0.0039 0.0046
Loa Loa (eye worm) abnormal chemotaxis protein 14 0.0041 0.0198 0.0291
Loa Loa (eye worm) tubulin gamma chain 0.0623 0.3873 0.5809
Echinococcus granulosus thyroid hormone receptor alpha 0.0013 0.0019 0.0018
Brugia malayi jmjC domain containing protein 0.0057 0.03 0.0444
Schistosoma mansoni tyrosyl-DNA phosphodiesterase 0.0064 0.0344 0.0405
Toxoplasma gondii CMGC kinase, MAPK family (ERK) MAPK-1 0.01 0.057 0.0855
Schistosoma mansoni patched 1 0.0041 0.0198 0.0233
Entamoeba histolytica tubulin family protein 0.1064 0.6665 1
Schistosoma mansoni hypothetical protein 0.004 0.0188 0.0222
Loa Loa (eye worm) hypothetical protein 0.0025 0.0095 0.0136
Trichomonas vaginalis PIKK family atypical protein kinase 0.0035 0.0161 0.0223
Trypanosoma cruzi ubiquitin carboxyl-terminal hydrolase, putative 0.0036 0.0165 0.0243
Schistosoma mansoni tubulin subunit alpha 0.0807 0.5039 0.5928
Schistosoma mansoni hepatocyte nuclear factor 4-alpha (hnf-4-alpha) 0.0013 0.0019 0.0022
Loa Loa (eye worm) hypothetical protein 0.0019 0.006 0.0084
Loa Loa (eye worm) hypothetical protein 0.0055 0.0287 0.0424
Loa Loa (eye worm) alpha-tubulin 0.0807 0.5039 0.7558
Schistosoma mansoni nuclear hormone receptor 0.0013 0.0019 0.0022
Echinococcus multilocularis bloom syndrome protein 0.0019 0.006 0.0056
Loa Loa (eye worm) hypothetical protein 0.0038 0.0176 0.0258
Leishmania major phosphatidylinositol 3-kinase, putative 0.0015 0.0032 0.0042
Toxoplasma gondii Kazal-type serine protease inhibitor domain-containing protein 0.0038 0.0176 0.0264
Loa Loa (eye worm) hypothetical protein 0.0012 0.0015 0.0017
Entamoeba histolytica P-glycoprotein-2 0.0021 0.007 0.0105
Brugia malayi tubulin alpha-2 chain 0.0807 0.5039 0.7558
Loa Loa (eye worm) nuclear hormone receptor family member nhr-49 0.0027 0.011 0.0159
Echinococcus multilocularis organic anion transporting polypeptide 30B 0.0055 0.0287 0.0283
Plasmodium falciparum thioredoxin reductase 0.0016 0.004 0.0009
Echinococcus multilocularis ecdysone induced protein 78C 0.0027 0.011 0.0106
Trichomonas vaginalis tubulin gamma chain, putative 0.0269 0.164 0.2445
Trichomonas vaginalis ATP-binding cassette transporter, putative 0.0021 0.007 0.0085
Trichomonas vaginalis guanylate cyclase, putative 0.0025 0.0095 0.0122
Plasmodium falciparum ataxin-2 like protein, putative 0.0049 0.0251 0.0326
Plasmodium falciparum tubulin gamma chain 0.0623 0.3873 0.579
Loa Loa (eye worm) hypothetical protein 0.003 0.0128 0.0187
Trichomonas vaginalis multidrug resistance protein 1, 2, putative 0.0021 0.007 0.0085
Trichomonas vaginalis PIKK family atypical protein kinase 0.0033 0.0147 0.0201
Echinococcus multilocularis multidrug resistance protein 1 0.0015 0.003 0.0026
Plasmodium vivax tubulin gamma chain, putative 0.0623 0.3873 0.5811
Echinococcus multilocularis Smad4 0.0016 0.0039 0.0035
Schistosoma mansoni hypothetical protein 0.0071 0.0384 0.0452
Echinococcus granulosus FTZ F1 alpha 0.0027 0.011 0.0125
Loa Loa (eye worm) hypothetical protein 0.0119 0.0692 0.1033
Brugia malayi CXXC zinc finger family protein 0.0028 0.0115 0.0166
Schistosoma mansoni NADP-specific isocitrate dehydrogenase 0.0015 0.0035 0.0041
Onchocerca volvulus 0.0064 0.0344 0.1637
Echinococcus granulosus Protein patched homolog 1 0.0041 0.0198 0.0228
Brugia malayi hypothetical protein 0.0049 0.0251 0.037
Schistosoma mansoni intermediate filament proteins 0.0026 0.0104 0.0122
Trypanosoma brucei beta tubulin 0.1064 0.6665 1
Leishmania major dihydrolipoamide dehydrogenase, putative 0.0016 0.004 0.0055
Trypanosoma brucei beta tubulin 0.0596 0.3704 0.5555
Trichomonas vaginalis ATP-binding cassette transporter, putative 0.0015 0.003 0.0025
Echinococcus granulosus histone lysine methyltransferase setb 0.003 0.0128 0.0147
Echinococcus multilocularis Tubulin alpha 1 chain 0.0807 0.5039 0.5037
Onchocerca volvulus 0.0055 0.0287 0.1349
Leishmania major isocitrate dehydrogenase [NADP], mitochondrial precursor, putative 0.0015 0.0035 0.0047
Schistosoma mansoni phosphatidylserine receptor 0.0015 0.0034 0.004
Echinococcus granulosus ecdysone induced protein 78C 0.0027 0.011 0.0125
Echinococcus multilocularis ubiquitin carboxyl terminal hydrolase 8 0.0036 0.0165 0.0162
Trypanosoma brucei zeta tubulin 0.0545 0.3384 0.5075
Trichomonas vaginalis taga, putative 0.0021 0.007 0.0085
Brugia malayi Nuclear hormone receptor E75 0.0013 0.0019 0.0023
Echinococcus multilocularis jumonji domain containing 1A 0.0015 0.0034 0.003
Echinococcus granulosus NADP dependent isocitrate dehydrogenase 0.0015 0.0035 0.0037
Mycobacterium tuberculosis Probable oxidoreductase 0.0119 0.0688 0.418
Brugia malayi tubulin alpha chain - mouse 0.0807 0.5039 0.7558
Echinococcus multilocularis mitogen activated protein kinase 3 0.01 0.057 0.0566
Loa Loa (eye worm) hypothetical protein 0.0027 0.011 0.0159
Trichomonas vaginalis ABC transporter, half transporter, putative 0.0021 0.007 0.0085
Echinococcus granulosus aryl hydrocarbon receptor 0.0025 0.0095 0.0107
Trypanosoma brucei zeta tubulin, putative 0.0545 0.3384 0.5075
Echinococcus multilocularis tubulin alpha 0.0596 0.3704 0.3702
Onchocerca volvulus Steroid hormone receptor family member cnr14 homolog 0.0027 0.011 0.0458
Loa Loa (eye worm) ATP-dependent DNA helicase 0.0019 0.006 0.0084
Schistosoma mansoni tubulin subunit epsilon 0.0622 0.3871 0.4554
Echinococcus multilocularis Solute carrier organic anion transporter family 0.0055 0.0287 0.0283
Loa Loa (eye worm) jmjC domain-containing protein 0.0015 0.0034 0.0046
Toxoplasma gondii target of rapamycin (TOR), putative 0.0033 0.0147 0.022
Brugia malayi Nuclear hormone receptor-like 1 0.0014 0.0029 0.0037
Echinococcus granulosus RUN 0.0059 0.0308 0.0358
Echinococcus granulosus lysine specific demethylase 5A 0.0059 0.031 0.036
Trichomonas vaginalis CMGC family protein kinase 0.01 0.057 0.0837
Trypanosoma brucei isocitrate dehydrogenase [NADP], mitochondrial precursor, putative 0.0015 0.0035 0.0047
Echinococcus multilocularis cpg binding protein 0.003 0.0125 0.0121
Trichomonas vaginalis PIKK family atypical protein kinase 0.0035 0.0161 0.0223
Plasmodium vivax glutathione reductase, putative 0.0047 0.0234 0.035
Schistosoma mansoni nuclear receptor 0.0013 0.0019 0.0022
Loa Loa (eye worm) tubulin alpha chain 0.0807 0.5039 0.7558
Brugia malayi MH1 domain containing protein 0.0016 0.0039 0.0052
Giardia lamblia Delta tubulin 0.0269 0.164 0.2414
Trichomonas vaginalis glutathione reductase, putative 0.0016 0.004 0.0041
Echinococcus granulosus tumor protein p63 0.0663 0.4131 0.4857
Trypanosoma brucei alpha tubulin, putative 0.0327 0.2003 0.3
Schistosoma mansoni ubiquitin-specific peptidase 8 (C19 family) 0.0036 0.0165 0.0195
Echinococcus multilocularis COUP TF:Svp nuclear hormone receptor 0.0027 0.011 0.0106
Loa Loa (eye worm) hypothetical protein 0.0013 0.0019 0.0023
Brugia malayi Ubiquitin carboxyl-terminal hydrolase family protein 0.0036 0.0165 0.0243
Schistosoma mansoni nuclear receptor 0.0013 0.0019 0.0022
Trypanosoma cruzi dihydrolipoamide dehydrogenase, putative 0.0016 0.004 0.0055
Echinococcus multilocularis Tubulin beta 2C chain 0.1064 0.6665 0.6664
Echinococcus multilocularis tubulin beta 1 chain 0.1064 0.6665 0.6664
Echinococcus multilocularis retinoic acid receptor rxr beta a retinoic acid receptor rxr alpha a retinoic acid receptor rxr alpha 0.0013 0.0019 0.0015
Brugia malayi ecdysone receptor 0.0013 0.0019 0.0023
Schistosoma mansoni cpg binding protein 0.0028 0.0115 0.0135
Trichomonas vaginalis adenylate cyclase, putative 0.0025 0.0095 0.0122
Loa Loa (eye worm) hypothetical protein 0.0015 0.0034 0.0046
Loa Loa (eye worm) pax transcription factor protein 2 0.0234 0.1419 0.2124
Loa Loa (eye worm) hypothetical protein 0.0027 0.011 0.0159
Schistosoma mansoni retinoid-x-receptor (RXR) 0.0027 0.011 0.0129
Brugia malayi conserved hypotetical protein 0.0013 0.0019 0.0023
Loa Loa (eye worm) aryl Hydrocarbon receptor Associated protein family member 0.0025 0.0095 0.0136
Mycobacterium ulcerans flavoprotein disulfide reductase 0.0016 0.004 0.0223
Trichomonas vaginalis PIKK family atypical protein kinase 0.0024 0.009 0.0115
Loa Loa (eye worm) tubulin beta chain 0.0269 0.164 0.2456
Toxoplasma gondii pyruvate dehydrogenase complex subunit PDH-E3II 0.0016 0.004 0.006
Trichomonas vaginalis PIKK family atypical protein kinase 0.0015 0.0032 0.0028
Schistosoma mansoni zinc finger protein 0.0013 0.0019 0.0022
Onchocerca volvulus 0.0234 0.1419 0.7058
Loa Loa (eye worm) hypothetical protein 0.0013 0.0019 0.0023
Trichomonas vaginalis lipid A export ATP-binding/permease protein msba, putative 0.0021 0.007 0.0085
Echinococcus multilocularis nuclear factor of activated T cells 5 0.0072 0.0391 0.0387
Echinococcus multilocularis nuclear receptor 2DBD gamma 0.0027 0.011 0.0106
Trypanosoma cruzi dihydrolipoamide dehydrogenase, putative 0.0016 0.004 0.0055
Trypanosoma cruzi beta tubulin, putative 0.1064 0.6665 1
Loa Loa (eye worm) Smad1 0.0016 0.0039 0.0052
Brugia malayi hypothetical protein 0.0014 0.0029 0.0037
Brugia malayi follicle stimulating hormone receptor 0.0231 0.1401 0.2097
Leishmania major delta tubulin, putative 0.0434 0.2683 0.4022
Brugia malayi ATP-dependent DNA helicase, RecQ family protein 0.0019 0.006 0.0084
Schistosoma mansoni ataxia telangiectasia mutated (atm)-related 0.0044 0.0219 0.0257
Trypanosoma cruzi mitogen-activated protein kinase 11, putative 0.01 0.057 0.085
Trichomonas vaginalis ATP-binding cassette transporter, putative 0.0021 0.007 0.0085
Brugia malayi Steroid receptor seven-up type 2 0.0027 0.011 0.0159
Loa Loa (eye worm) nuclear Hormone Receptor family member 0.0027 0.011 0.0159
Echinococcus granulosus ankyrin repeat and death domain containing protein 0.0014 0.0026 0.0026
Echinococcus granulosus thioredoxin glutathione reductase 0.0047 0.0234 0.027
Trypanosoma cruzi trypanothione reductase, putative 0.0016 0.004 0.0055
Echinococcus multilocularis FKBP12 rapamycin complex associated protein 0.0044 0.0219 0.0215
Loa Loa (eye worm) tubulin beta-4 chain 0.1064 0.6665 1
Plasmodium vivax isocitrate dehydrogenase [NADP], mitochondrial, putative 0.0015 0.0035 0.0053
Echinococcus granulosus ubiquitin carboxyl terminal hydrolase 8 0.0036 0.0165 0.019
Echinococcus multilocularis agrin 0.0038 0.0176 0.0172
Leishmania major alpha tubulin 0.0807 0.5039 0.7558
Trypanosoma cruzi tubulin gamma chain 0.0623 0.3873 0.5809
Leishmania major gamma-tubulin 0.0623 0.3873 0.5809
Echinococcus granulosus organic anion transporting polypeptide 30B 0.0055 0.0287 0.0333
Loa Loa (eye worm) nuclear hormone receptor family member nhr-31 0.0027 0.011 0.0159
Loa Loa (eye worm) hypothetical protein 0.0021 0.0068 0.0097
Trichomonas vaginalis conserved hypothetical protein 0.0269 0.164 0.2445
Loa Loa (eye worm) jmjC domain-containing protein 0.0015 0.0034 0.0046
Brugia malayi Nuclear hormone receptor family member nhr-19 0.0027 0.011 0.0159

Activities

No activities found for this compound.

Phenotypes

Whole-cell/tissue/organism interactions

We have no records of whole-cell/tissue assays done with this compound What does this mean?

Many chemical entities in TDR Targets come from high-throughput screenings with whole cells or tissue samples, and not all assayed compounds have been tested against a single a single target protein, probably because they get ruled out during screening process. Even if these compounds may have not been of interest in the original screening, they may come as interesting leads for other screening assays. Furthermore, we may be able to propose drug-target associations using chemical similarities and network patterns.

Annotated phenotypes:

We have no manually annotated phenotypes for this drug. What does this mean? / Care to help?
In TDR Targets, information about phenotypes that are caused by drugs, or by genetic manipulation of cells (e.g. gene knockouts or knockdowns) is manually curated from the literature. These descriptions help to describe the potential of the target for drug development. If no information is available for this gene or if the information is incomplete, this may mean that i) the papers containing this information either appeared after the curation effort for this organism was carried out or they were inadvertently missed by curators; or that ii) the curation effort for this organism has not yet started.
 
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External resources for this compound

Bibliographic References

No literature references available for this target.

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