Detailed information for compound 86281

Basic information

Technical information
  • Name: Unnamed compound
  • MW: 409.326 | Formula: C21H24Cl2NO3-
  • H donors: 2 H acceptors: 2 LogP: 4.7 Rotable bonds: 7
    Rule of 5 violations (Lipinski): 1
  • SMILES: CCOC(=O)c1ccc2c(c1)CC(CC2)NCC(c1cccc(c1)Cl)O.[Cl-]
  • InChi: 1S/C21H24ClNO3.ClH/c1-2-26-21(25)16-7-6-14-8-9-19(12-17(14)10-16)23-13-20(24)15-4-3-5-18(22)11-15;/h3-7,10-11,19-20,23-24H,2,8-9,12-13H2,1H3;1H/p-1
  • InChiKey: NNBDAERRXFAUII-UHFFFAOYSA-M  


Substructure search Similarity search

Network

Hover on a compound node to display the structore

Synonyms

No synonyms found for this compound

Targets

Known targets for this compound

No curated genes were found associated with this compound

Predicted pathogen targets for this compound

By orthology
No druggable targets predicted by orthology data
By sequence similarity to non orthologous known druggable targets
No druggable targets predicted by sequence similarity
Obtained from network model

Ranking Plot

Putative Targets List

Species Potential target Raw Global Species
Echinococcus granulosus tumor protein p63 0.0751 0.3043 0.7735
Onchocerca volvulus 0.0149 0.0544 0.3679
Brugia malayi Smad1 0.0033 0.0061 0.0155
Schistosoma mansoni serine/threonine protein kinase 0.0052 0.0143 0.0351
Plasmodium falciparum glutathione reductase 0.005 0.0133 0.3184
Echinococcus granulosus sodium:glucose cotransporter 2 0.0039 0.0088 0.0212
Brugia malayi MH2 domain containing protein 0.0033 0.0061 0.0155
Schistosoma mansoni mixed-lineage leukemia protein mll 0.003 0.0049 0.0113
Echinococcus multilocularis histone lysine N methyltransferase MLL3 0.0037 0.0078 0.0074
Schistosoma mansoni hypothetical protein 0.0043 0.0102 0.0248
Trypanosoma cruzi acetyl-CoA synthetase, putative 0.0029 0.0046 0.0295
Loa Loa (eye worm) hypothetical protein 0.0126 0.0448 0.1139
Brugia malayi 3'5'-cyclic nucleotide phosphodiesterase family protein 0.025 0.0962 0.2444
Schistosoma mansoni nuclear hormone receptor 0.0059 0.0172 0.0426
Loa Loa (eye worm) nuclear receptor nhr-7B 0.0059 0.0172 0.0436
Trichomonas vaginalis sucrase-isomaltase, putative 0.0036 0.0075 0.0474
Echinococcus granulosus ATP dependent Clp protease proteolytic subunit 0.0083 0.0268 0.067
Echinococcus granulosus cadherin EGF LAG seven pass G type receptor 0.0047 0.0121 0.0297
Mycobacterium tuberculosis Probable hydrolase 0.0111 0.0384 0.1308
Echinococcus multilocularis lysosomal alpha glucosidase 0.0163 0.06 0.0595
Echinococcus granulosus high affinity cgmp specific 3' 5' cyclic 0.0045 0.0111 0.027
Loa Loa (eye worm) hypothetical protein 0.0102 0.0349 0.0886
Brugia malayi nuclear receptor NHR-88 0.0059 0.0172 0.0436
Echinococcus multilocularis Niemann Pick C1 protein 0.0147 0.0536 0.0532
Schistosoma mansoni family S12 unassigned peptidase (S12 family) 0.0111 0.0384 0.0966
Giardia lamblia Hypothetical protein 0.0045 0.0111 0.7557
Echinococcus granulosus acetyl coenzyme A synthetase cytoplasmic 0.0029 0.0046 0.0105
Onchocerca volvulus 0.011 0.0382 0.2571
Trichomonas vaginalis calcium/calmodulin-dependent 3,5-cyclic nucleotide phosphodiesterase, putative 0.0341 0.1342 1
Brugia malayi MH2 domain containing protein 0.0481 0.1922 0.4888
Echinococcus granulosus nuclear receptor 2DBD gamma 0.0126 0.0448 0.1129
Mycobacterium ulcerans long-chain-fatty-acid-CoA ligase 0.0099 0.0337 0.5834
Loa Loa (eye worm) hypothetical protein 0.0126 0.0448 0.1139
Schistosoma mansoni histone-lysine n-methyltransferase setb1 0.0049 0.0127 0.031
Mycobacterium ulcerans long-chain-fatty-acid--CoA ligase 0.0029 0.0046 0.0616
Schistosoma mansoni hypothetical protein 0.0047 0.0121 0.0297
Echinococcus multilocularis guanine nucleotide binding protein G(s) subunit 0.0391 0.1549 0.1545
Mycobacterium tuberculosis Probable medium chain fatty-acid-CoA ligase FadD14 (fatty-acid-CoA synthetase) (fatty-acid-CoA synthase) 0.0029 0.0046 0.0121
Toxoplasma gondii hypothetical protein 0.0257 0.0993 1
Loa Loa (eye worm) hypothetical protein 0.0099 0.0337 0.0857
Trypanosoma brucei cAMP-specific phosphodiesterase 0.0302 0.1178 1
Schistosoma mansoni smad1 5 8 and 0.0033 0.0061 0.0144
Schistosoma mansoni nuclear hormone receptor 0.0126 0.0448 0.1129
Loa Loa (eye worm) hypothetical protein 0.0044 0.0109 0.0275
Trypanosoma brucei cAMP-specific phosphodiesterase, putative 0.0045 0.0111 0.0848
Loa Loa (eye worm) hypothetical protein 0.0074 0.0233 0.0592
Mycobacterium tuberculosis Adenosylmethionine-8-amino-7-oxononanoate aminotransferase BioA 0.015 0.0547 0.188
Brugia malayi Latrophilin receptor protein 2 0.0047 0.0121 0.0307
Echinococcus granulosus COUP TF:Svp nuclear hormone receptor 0.0126 0.0448 0.1129
Trypanosoma cruzi GAF domain/TIP41-like family, putative 0.0039 0.0089 0.0661
Echinococcus granulosus neuropeptide s receptor 0.0949 0.3863 0.9824
Echinococcus multilocularis acetyl coenzyme A synthetase, cytoplasmic 0.0029 0.0046 0.0041
Loa Loa (eye worm) hypothetical protein 0.0099 0.0337 0.0857
Brugia malayi F/Y-rich N-terminus family protein 0.0038 0.0084 0.0214
Schistosoma mansoni hypothetical protein 0.0149 0.0544 0.1373
Trypanosoma cruzi glycerol uptake protein, putative 0.0083 0.0271 0.2218
Trichomonas vaginalis conserved hypothetical protein 0.0083 0.0271 0.1945
Echinococcus granulosus arachidonate 5 lipoxygenase 0.0054 0.0148 0.0365
Loa Loa (eye worm) DR-78 0.0059 0.0172 0.0436
Mycobacterium leprae Probable lipase LipE 0.0111 0.0384 0.6951
Trichomonas vaginalis conserved hypothetical protein 0.0341 0.1342 1
Echinococcus multilocularis neuropeptide s receptor 0.0949 0.3863 0.386
Mycobacterium tuberculosis Probable fatty-acid-CoA ligase FadD7 (fatty-acid-CoA synthetase) (fatty-acid-CoA synthase) 0.007 0.0216 0.0718
Brugia malayi conserved hypotetical protein 0.0059 0.0172 0.0436
Schistosoma mansoni cpg binding protein 0.0124 0.0442 0.1112
Trichomonas vaginalis calcium/calmodulin-dependent 3,5-cyclic nucleotide phosphodiesterase, putative 0.0302 0.1178 0.8769
Trichomonas vaginalis conserved hypothetical protein 0.0257 0.0993 0.7375
Toxoplasma gondii ABC1 family protein 0.0111 0.0384 0.3796
Brugia malayi MAP kinase sur-1 0.0052 0.0143 0.0362
Wolbachia endosymbiont of Brugia malayi ATP-dependent Clp protease proteolytic subunit 0.0083 0.0268 1
Loa Loa (eye worm) hypothetical protein 0.025 0.0962 0.2444
Entamoeba histolytica hypothetical protein 0.0221 0.0842 1
Mycobacterium tuberculosis Fatty-acid-CoA synthetase FadD17 (fatty-acid-CoA synthase) (fatty-acid-CoA ligase) 0.0029 0.0046 0.0121
Mycobacterium tuberculosis Probable esterase/lipase LipP 0.0111 0.0384 0.1308
Schistosoma mansoni ap endonuclease 0.0021 0.0012 0.0018
Brugia malayi Bromodomain containing protein 0.0081 0.0263 0.0668
Trypanosoma cruzi hypothetical protein, conserved 0.0045 0.0111 0.0848
Loa Loa (eye worm) hypothetical protein 0.0103 0.0353 0.0896
Schistosoma mansoni hypothetical protein 0.0083 0.0271 0.0676
Trichomonas vaginalis rod cGMP-specific 3,5-cyclic phosphodiesterase, putative 0.0302 0.1178 0.8769
Trypanosoma cruzi cyclic nucleotide phosphodiesterase 0.0045 0.0111 0.0848
Brugia malayi Nuclear hormone receptor family member nhr-1 0.0126 0.0448 0.1139
Echinococcus granulosus smad 0.0033 0.0061 0.0144
Loa Loa (eye worm) diacylglycerol acyltransferase 0.0083 0.0271 0.0687
Schistosoma mansoni photoreceptor-specific nuclear receptor related 0.0126 0.0448 0.1129
Echinococcus granulosus dual 3'5' cyclic AMP and GMP phosphodiesterase 0.0302 0.1178 0.2988
Entamoeba histolytica hypothetical protein 0.0083 0.0271 0.3118
Echinococcus multilocularis Niemann Pick C1 protein 0.0103 0.0353 0.0348
Schistosoma mansoni o-acyltransferase (membrane bound) domain containing protein 0.0083 0.0271 0.0676
Echinococcus multilocularis expressed conserved protein 0.0097 0.0327 0.0322
Trichomonas vaginalis chromodomain-helicase-DNA-binding protein, putative 0.0026 0.0034 0.0168
Echinococcus granulosus DNA apurinic or apyrimidinic site lyase 0.0021 0.0012 0.0018
Toxoplasma gondii 3'5'-cyclic nucleotide phosphodiesterase domain-containing protein 0.0045 0.0111 0.1008
Entamoeba histolytica hypothetical protein 0.0221 0.0842 1
Echinococcus granulosus single minded 2 0.0038 0.0083 0.0199
Trypanosoma brucei inositol-1(or 4)-monophosphatase 1, putative 0.0039 0.0087 0.0646
Loa Loa (eye worm) hypothetical protein 0.0111 0.0384 0.0976
Trichomonas vaginalis cAMP and cAMP-inhibited cGMP 3,5-cyclic phosphodiesterase, putative 0.0186 0.0698 0.5155
Brugia malayi nuclear receptor NHR-88 0.0126 0.0448 0.1139
Loa Loa (eye worm) hypothetical protein 0.0059 0.0172 0.0436
Echinococcus multilocularis transfer RNA-Lys 0.0038 0.0083 0.0078
Loa Loa (eye worm) RNA binding protein 0.02 0.0756 0.1923
Echinococcus multilocularis sterol O acyltransferase 1 0.0083 0.0271 0.0266
Echinococcus granulosus histone lysine N methyltransferase MLL3 0.003 0.0049 0.0113
Toxoplasma gondii Acetyl-coenzyme A synthetase 2, putative 0.0029 0.0046 0.035
Schistosoma mansoni camp/cgmp cyclic nucleotide phosphodiesterase 0.0302 0.1178 0.2988
Brugia malayi Nuclear hormone receptor E75 0.0059 0.0172 0.0436
Schistosoma mansoni thyroid hormone receptor 0.0126 0.0448 0.1129
Echinococcus granulosus ecdysone induced protein 78C 0.0126 0.0448 0.1129
Loa Loa (eye worm) hypothetical protein 0.0045 0.0111 0.028
Trichomonas vaginalis conserved hypothetical protein 0.0026 0.0034 0.0168
Brugia malayi MBOAT family protein 0.0966 0.3932 1
Onchocerca volvulus 0.0038 0.0083 0.0534
Echinococcus granulosus fetal alzheimer antigen falz 0.0029 0.0046 0.0105
Echinococcus granulosus lamin dm0 0.0026 0.0034 0.0074
Schistosoma mansoni single-minded 0.0051 0.0139 0.034
Loa Loa (eye worm) hypothetical protein 0.0083 0.0271 0.0687
Trichomonas vaginalis CMGC family protein kinase 0.0052 0.0143 0.0984
Entamoeba histolytica membrane-bound O-acyltransferase (MBOAT ) family protein 0.0083 0.0271 0.3118
Echinococcus granulosus neuropeptide receptor A26 0.0949 0.3863 0.9824
Trypanosoma brucei hypothetical protein, conserved 0.0045 0.0111 0.0848
Loa Loa (eye worm) hypothetical protein 0.0067 0.0202 0.0511
Schistosoma mansoni camp-specific 35-cyclic phosphodiesterase 0.0045 0.0111 0.027
Plasmodium vivax hypothetical protein, conserved 0.0111 0.0384 0.9458
Trichomonas vaginalis CMGC family protein kinase 0.0052 0.0143 0.0984
Trypanosoma cruzi hypothetical protein, conserved 0.0036 0.0075 0.0541
Mycobacterium ulcerans acyl-CoA synthetase 0.0029 0.0046 0.0616
Toxoplasma gondii 3'5'-cyclic nucleotide phosphodiesterase domain-containing protein 0.0045 0.0111 0.1008
Echinococcus multilocularis lysosomal alpha glucosidase 0.0163 0.06 0.0595
Loa Loa (eye worm) exodeoxyribonuclease III family protein 0.0021 0.0012 0.0029
Trypanosoma cruzi mitogen activated protein kinase 4, putative 0.0052 0.0143 0.1122
Schistosoma mansoni tar DNA-binding protein 0.02 0.0756 0.1914
Brugia malayi MBOAT family protein 0.0083 0.0271 0.0687
Plasmodium vivax 3',5'-cyclic nucleotide phosphodiesterase, putative 0.0045 0.0111 0.2639
Schistosoma mansoni aldehyde dehydrogenase 0.0072 0.0224 0.0559
Brugia malayi Corticotropin releasing factor receptor 2 precursor, putative 0.0149 0.0545 0.1385
Schistosoma mansoni peptidase Clp (S14 family) 0.0083 0.0268 0.067
Loa Loa (eye worm) transcription factor SMAD2 0.0481 0.1922 0.4888
Brugia malayi TAR-binding protein 0.02 0.0756 0.1923
Trichomonas vaginalis calcium/calmodulin-dependent 3,5-cyclic nucleotide phosphodiesterase, putative 0.0302 0.1178 0.8769
Schistosoma mansoni acetyl-CoA synthetase 0.0029 0.0046 0.0105
Mycobacterium tuberculosis Possible fatty-acid-CoA ligase FadD1 (fatty-acid-CoA synthetase) (fatty-acid-CoA synthase) 0.0029 0.0046 0.0121
Brugia malayi AMP-binding enzyme family protein 0.0029 0.0046 0.0116
Trypanosoma cruzi cAMP specific phosphodiesterase, putative 0.0302 0.1178 1
Trypanosoma brucei cAMP phosphodiesterase A, putative 0.0045 0.0111 0.0848
Echinococcus multilocularis membrane bound acyltransferase:hhat 0.0083 0.0271 0.0266
Plasmodium falciparum cGMP-specific phosphodiesterase 0.0045 0.0111 0.2639
Toxoplasma gondii 3'5'-cyclic nucleotide phosphodiesterase domain-containing protein 0.0045 0.0111 0.1008
Plasmodium vivax diacylglycerol O-acyltransferase, putative 0.0083 0.0271 0.6624
Trichomonas vaginalis cAMP-specific 3,5-cyclic phosphodiesterase, putative 0.0302 0.1178 0.8769
Mycobacterium ulcerans acyl-CoA synthetase 0.0029 0.0046 0.0616
Echinococcus multilocularis calcium:calmodulin dependent 3',5' cyclic 0.0045 0.0111 0.0106
Trichomonas vaginalis cGMP-specific 3,5-cyclic phosphodiesterase, putative 0.0302 0.1178 0.8769
Loa Loa (eye worm) RNA recognition domain-containing protein domain-containing protein 0.02 0.0756 0.1923
Schistosoma mansoni zinc finger protein 0.0059 0.0172 0.0426
Leishmania major acetyl-CoA synthetase, putative 0.0029 0.0046 0.0392
Toxoplasma gondii ornithine aminotransferase, mitochondrial precursor, putative 0.0021 0.0014 0.0018
Mycobacterium ulcerans hypothetical protein 0.0111 0.0384 0.6675
Schistosoma mansoni nuclear hormone receptor nor-1/nor-2 0.0126 0.0448 0.1129
Schistosoma mansoni alpha-glucosidase 0.014 0.0506 0.1276
Mycobacterium tuberculosis Probable chain -fatty-acid-CoA ligase FadD13 (fatty-acyl-CoA synthetase) 0.0099 0.0337 0.1144
Echinococcus multilocularis zinc finger protein 0.0882 0.3587 0.3584
Brugia malayi Nuclear hormone receptor-like 1 0.0126 0.0448 0.1139
Toxoplasma gondii GAF domain-containing protein 0.0116 0.0406 0.4018
Mycobacterium ulcerans acyl-CoA synthetase 0.0029 0.0046 0.0616
Echinococcus granulosus Niemann Pick C1 protein 0.0103 0.0353 0.0886
Mycobacterium tuberculosis Probable ATP-dependent CLP protease proteolytic subunit 1 ClpP1 (endopeptidase CLP) 0.0054 0.015 0.0485
Loa Loa (eye worm) PDE1B protein 0.0045 0.0111 0.028
Plasmodium vivax hypothetical protein, conserved 0.0116 0.0406 1
Mycobacterium tuberculosis Bifunctional enzyme MbtA: salicyl-AMP ligase (SAL-AMP ligase) + salicyl-S-ArCP synthetase 0.0029 0.0046 0.0121
Mycobacterium ulcerans acyl-CoA synthetase 0.0029 0.0046 0.0616
Trichomonas vaginalis antibiotic synthetase, putative 0.0029 0.0046 0.0258
Loa Loa (eye worm) hypothetical protein 0.0045 0.0111 0.028
Echinococcus multilocularis o acyltransferase (membrane bound) domain 0.0083 0.0271 0.0266
Loa Loa (eye worm) beta-LACTamase domain containing family member 0.0111 0.0384 0.0976
Schistosoma mansoni nuclear receptor 0.0059 0.0172 0.0426
Schistosoma mansoni aldehyde dehydrogenase 0.0072 0.0224 0.0559
Mycobacterium tuberculosis Probable reductase 0.0114 0.0398 0.1357
Echinococcus granulosus FTZ F1 nuclear receptor protein 0.0126 0.0448 0.1129
Echinococcus multilocularis neutral alpha glucosidase AB 0.0036 0.0075 0.007
Loa Loa (eye worm) hypothetical protein 0.0067 0.0202 0.0511
Toxoplasma gondii acyl-CoA:cholesterol acyltransferase alpha ACAT1-alpha 0.0083 0.0271 0.2637
Mycobacterium ulcerans phenyloxazoline synthase MbtB 0.0029 0.0046 0.0616
Schistosoma mansoni Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) 0.0391 0.1549 0.3931
Mycobacterium ulcerans acyl-CoA synthetase 0.0099 0.0337 0.5834
Schistosoma mansoni coup transcription factor 0.0126 0.0448 0.1129
Echinococcus granulosus FTZ F1 alpha 0.0126 0.0448 0.1129
Loa Loa (eye worm) hypothetical protein 0.011 0.0382 0.0969
Schistosoma mansoni histone-lysine n-methyltransferase suv9 0.0032 0.0056 0.0131
Loa Loa (eye worm) nuclear hormone receptor family member nhr-49 0.0126 0.0448 0.1139
Leishmania major hypothetical protein, conserved 0.0045 0.0111 0.094
Echinococcus granulosus Protein patched homolog 1 0.0044 0.0109 0.0264
Brugia malayi Intermediate filament tail domain containing protein 0.0026 0.0034 0.0085
Mycobacterium leprae conserved hypothetical protein 0.0116 0.0406 0.7359
Trichomonas vaginalis alpha-glucosidase, putative 0.0036 0.0075 0.0474
Onchocerca volvulus 0.0111 0.0384 0.2589
Mycobacterium tuberculosis Probable nitrite reductase [NAD(P)H] large subunit [FAD flavoprotein] NirB 0.0114 0.0398 0.1357
Echinococcus multilocularis Smad4 0.0033 0.0061 0.0056
Plasmodium falciparum ATP-dependent Clp protease proteolytic subunit 0.0028 0.0043 0.096
Schistosoma mansoni lamin 0.0026 0.0034 0.0074
Trypanosoma cruzi cAMP phosphodiesterase A, putative 0.0045 0.0111 0.0848
Brugia malayi 3'5'-cyclic nucleotide phosphodiesterase family protein 0.0045 0.0111 0.028
Mycobacterium ulcerans 4-aminobutyrate aminotransferase 0.0021 0.0014 0.0031
Leishmania major glycerol uptake protein, putative 0.0083 0.0271 0.2296
Echinococcus granulosus cAMP specific 3'5' cyclic phosphodiesterase 0.0045 0.0111 0.027
Loa Loa (eye worm) hypothetical protein 0.0067 0.0202 0.0511
Echinococcus multilocularis o acyltransferase (membrane bound) domain 0.0083 0.0271 0.0266
Onchocerca volvulus Nuclear receptor subfamily 6 group A member 1 homolog 0.0059 0.0172 0.114
Toxoplasma gondii 3'5'-cyclic nucleotide phosphodiesterase domain-containing protein 0.0045 0.0111 0.1008
Trichomonas vaginalis porcupine, putative 0.0083 0.0271 0.1945
Echinococcus multilocularis nuclear receptor 2DBD gamma 0.0126 0.0448 0.0444
Echinococcus granulosus ornithine aminotransferase 0.0021 0.0014 0.0022
Schistosoma mansoni ecdysone-induced protein 78c (dr-78) 0.0067 0.0202 0.0501
Echinococcus granulosus calcium:calmodulin dependent 3'5' cyclic 0.0045 0.0111 0.027
Mycobacterium ulcerans peptide synthetase Nrp (peptide synthase) 0.0029 0.0046 0.0616
Mycobacterium tuberculosis Conserved hypothetical protein 0.0039 0.0089 0.0271
Echinococcus multilocularis nuclear receptor nhr 48 0.0059 0.0172 0.0167
Brugia malayi Bromodomain containing protein 0.0038 0.0084 0.0212
Entamoeba histolytica membrane-bound O-acyltransferase (MBOAT ) family protein 0.0083 0.0271 0.3118
Echinococcus granulosus bromodomain adjacent to zinc finger domain 0.0036 0.0074 0.0176
Loa Loa (eye worm) hypothetical protein 0.0111 0.0384 0.0976
Toxoplasma gondii inositol(myo)-1(or 4)-monophosphatase 2, putative 0.0039 0.0087 0.0768
Loa Loa (eye worm) hypothetical protein 0.0059 0.0172 0.0436
Entamoeba histolytica hypothetical protein 0.0221 0.0842 1
Mycobacterium ulcerans acyl-CoA synthetase 0.0029 0.0046 0.0616
Echinococcus granulosus peptidase Clp S14 family 0.0054 0.015 0.0369
Echinococcus granulosus TGF beta signal transducer SmadC 0.0033 0.0061 0.0144
Brugia malayi Probable 3',5'-cyclic phosphodiesterase C32E12.2, putative 0.038 0.1503 0.382
Loa Loa (eye worm) hypothetical protein 0.0059 0.0172 0.0436
Schistosoma mansoni hypothetical protein 0.0043 0.0102 0.0248
Brugia malayi hypothetical protein 0.0172 0.0641 0.1629
Schistosoma mansoni high-affinity cgmp-specific 35-cyclic phosphodiesterase 0.0045 0.0111 0.027
Trypanosoma cruzi trypanothione reductase, putative 0.005 0.0133 0.1035
Brugia malayi Nuclear hormone receptor family member nhr-3 0.0126 0.0448 0.1139
Trichomonas vaginalis penicillin-binding protein, putative 0.0111 0.0384 0.2799
Mycobacterium ulcerans two component sensor histidine kinase DevS 0.0155 0.057 1
Loa Loa (eye worm) hypothetical protein 0.0083 0.0271 0.0687
Schistosoma mansoni histone-lysine n-methyltransferase setb1 0.0049 0.0127 0.031
Brugia malayi beta-lactamase family protein 0.0111 0.0384 0.0976
Toxoplasma gondii 3'5'-cyclic nucleotide phosphodiesterase domain-containing protein 0.0045 0.0111 0.1008
Mycobacterium tuberculosis Probable conserved lipoprotein 0.0111 0.0384 0.1308
Echinococcus granulosus retinoic acid receptor rxr beta a 0.0126 0.0448 0.1129
Trichomonas vaginalis chromodomain helicase DNA binding protein, putative 0.0026 0.0034 0.0168
Schistosoma mansoni alpha-glucosidase 0.014 0.0506 0.1276
Mycobacterium leprae PROBABLE FATTY-ACID-CoA LIGASE FADD7 (FATTY-ACID-CoA SYNTHETASE) (FATTY-ACID-CoA SYNTHASE) 0.0099 0.0337 0.6071
Mycobacterium tuberculosis Probable esterase LipL 0.0111 0.0384 0.1308
Schistosoma mansoni smad1 5 8 and 0.0033 0.0061 0.0144
Onchocerca volvulus 0.0083 0.0271 0.1813
Leishmania major mitogen activated protein kinase, putative,map kinase, putative 0.0052 0.0143 0.1211
Brugia malayi Ligand-binding domain of nuclear hormone receptor family protein 0.0126 0.0448 0.1139
Echinococcus multilocularis tar DNA binding protein 0.02 0.0756 0.0752
Mycobacterium leprae PROBABLE ATP-DEPENDENT CLP PROTEASE PROTEOLYTIC SUBUNIT 2 CLPP2 (ENDOPEPTIDASE CLP 2) 0.0083 0.0268 0.4774
Echinococcus multilocularis sodium:myo inositol cotransporter 0.0039 0.0088 0.0083
Mycobacterium ulcerans esterase/lipase LipP 0.0111 0.0384 0.6675
Brugia malayi hypothetical protein 0.0731 0.2959 0.7523
Mycobacterium tuberculosis Conserved protein 0.0111 0.0384 0.1308
Echinococcus multilocularis nuclear receptor 2DBD gamma 0.0059 0.0172 0.0167
Brugia malayi Inositol-1 0.0039 0.0087 0.022
Schistosoma mansoni hypothetical protein 0.0047 0.0121 0.0297
Trypanosoma cruzi myo-inositol-1(or 4)-monophosphatase 1, putative 0.0039 0.0087 0.0646
Echinococcus granulosus o acyltransferase membrane bound domain 0.0083 0.0271 0.0676
Onchocerca volvulus Nuclear receptor subfamily 6 group A member 1 homolog 0.0059 0.0172 0.114
Echinococcus granulosus cAMP specific 3'5' cyclic phosphodiesterase 0.0045 0.0111 0.027
Trypanosoma brucei glucosidase, putative 0.0036 0.0075 0.0541
Echinococcus granulosus Nuclear hormone receptor HR96 0.0059 0.0172 0.0426
Plasmodium falciparum 3',5'-cyclic nucleotide phosphodiesterase, putative 0.0045 0.0111 0.2639
Echinococcus granulosus inositol monophosphatase 1 0.0039 0.0087 0.021
Toxoplasma gondii aldehyde dehydrogenase 0.0072 0.0224 0.2166
Toxoplasma gondii 3'5'-cyclic nucleotide phosphodiesterase domain-containing protein 0.0045 0.0111 0.1008
Brugia malayi Iron-sulfur cluster assembly accessory protein 0.0149 0.0544 0.1382
Loa Loa (eye worm) hhat protein 0.0083 0.0271 0.0687
Trichomonas vaginalis helicase, putative 0.0026 0.0034 0.0168
Loa Loa (eye worm) nuclear hormone receptor family member nhr-41 0.0126 0.0448 0.1139
Echinococcus granulosus mothers against decapentaplegic 5 0.0033 0.0061 0.0144
Schistosoma mansoni RAR-like nuclear receptor 0.0126 0.0448 0.1129
Schistosoma mansoni steroid hormone receptor ad4bp 0.0126 0.0448 0.1129
Entamoeba histolytica acyl-CoA synthetase, putative 0.0099 0.0337 0.3922
Brugia malayi hypothetical protein 0.0067 0.0202 0.0511
Plasmodium falciparum acetyl-CoA synthetase, putative 0.0029 0.0046 0.1031
Schistosoma mansoni hypothetical protein 0.0043 0.0102 0.0248
Brugia malayi PHD-finger family protein 0.0031 0.0056 0.0141
Trypanosoma brucei 3', 5'-cyclic nucleotide phosphodiesterase, putative 0.0045 0.0111 0.0848
Mycobacterium tuberculosis Possible fatty-acid-CoA ligase FadD10 (fatty-acid-CoA synthetase) (fatty-acid-CoA synthase) 0.0029 0.0046 0.0121
Loa Loa (eye worm) hypothetical protein 0.0126 0.0448 0.1139
Schistosoma mansoni retinoid-x-receptor (RXR) 0.0067 0.0202 0.0501
Brugia malayi calcium-independent alpha-latrotoxin receptor 2, putative 0.0047 0.0121 0.0307
Echinococcus granulosus aldehyde dehydrogenase mitochondrial 0.0072 0.0224 0.0559
Loa Loa (eye worm) CXXC zinc finger family protein 0.0116 0.0406 0.1032
Echinococcus granulosus sodium:glucose cotransporter 0.0039 0.0088 0.0212
Onchocerca volvulus Rap guanine nucleotide exchange factor 1 homolog 0.0194 0.0729 0.4944
Trichomonas vaginalis cyclic nucleotide phosphodiesterase, putative 0.0045 0.0111 0.0743
Echinococcus multilocularis mothers against decapentaplegic 5 0.0033 0.0061 0.0056
Loa Loa (eye worm) AMP-binding enzyme family protein 0.0029 0.0046 0.0116
Echinococcus granulosus sodium:myo inositol cotransporter 0.0039 0.0088 0.0212
Brugia malayi GH02984p 0.0356 0.1402 0.3564
Mycobacterium ulcerans hypothetical protein 0.0099 0.0337 0.5834
Echinococcus granulosus high affinity choline transporter 1 0.0356 0.1402 0.3557
Trichomonas vaginalis cAMP-specific phosphodiesterase, putative 0.0186 0.0698 0.5155
Trichomonas vaginalis transmembrane protein nessy, putative 0.0083 0.0271 0.1945
Mycobacterium ulcerans extragenic suppressor protein SuhB 0.0039 0.0087 0.135
Schistosoma mansoni calcium/calmodulin-dependent 35-cyclic nucleotide phosphodiesterase 0.0045 0.0111 0.027
Brugia malayi Nuclear hormone receptor family member nhr-14 0.0126 0.0448 0.1139
Mycobacterium ulcerans acyl-CoA synthetase 0.0029 0.0046 0.0616
Echinococcus granulosus lysosomal alpha glucosidase 0.0163 0.06 0.1515
Loa Loa (eye worm) hypothetical protein 0.0083 0.0268 0.0681
Echinococcus granulosus lysophospholipid acyltransferase 7 0.0083 0.0271 0.0676
Mycobacterium ulcerans ATP-dependent Clp protease proteolytic subunit 0.0083 0.0268 0.4594
Echinococcus multilocularis Aminotransferase class III 0.0021 0.0014 0.0009
Schistosoma mansoni acetyl-CoA C-acetyltransferase 0.0029 0.0046 0.0105
Brugia malayi N-terminal motif family protein 0.0194 0.0729 0.1854
Onchocerca volvulus Huntingtin homolog 0.0372 0.147 1
Echinococcus granulosus nuclear receptor nhr 48 0.0059 0.0172 0.0426
Brugia malayi glutathione reductase 0.005 0.0133 0.0336
Trichomonas vaginalis cAMP and cAMP-inhibited cGMP 3,5-cyclic phosphodiesterase, putative 0.0045 0.0111 0.0743
Chlamydia trachomatis ATP-dependent Clp protease proteolytic subunit 0.0083 0.0268 1
Schistosoma mansoni hypothetical protein 0.0043 0.0102 0.0248
Schistosoma mansoni leukocyte receptor cluster (lrc) member 4 protein 0.0083 0.0271 0.0676
Echinococcus multilocularis high affinity cAMP specific 3',5' cyclic 0.0045 0.0111 0.0106
Loa Loa (eye worm) steroid hormone receptor 0.0126 0.0448 0.1139
Loa Loa (eye worm) hypothetical protein 0.0059 0.0172 0.0436
Loa Loa (eye worm) glutathione reductase 0.005 0.0133 0.0336
Loa Loa (eye worm) hypothetical protein 0.0111 0.0384 0.0976
Echinococcus multilocularis histone lysine N methyltransferase MLL3 0.003 0.0049 0.0044
Mycobacterium tuberculosis Probable fatty-acid-CoA ligase FadD2 (fatty-acid-CoA synthetase) (fatty-acid-CoA synthase) 0.0099 0.0337 0.1144
Loa Loa (eye worm) hypothetical protein 0.0029 0.0046 0.0116
Onchocerca volvulus 0.0029 0.0046 0.0282
Echinococcus multilocularis Nuclear hormone receptor HR96 0.0059 0.0172 0.0167
Schistosoma mansoni family S12 unassigned peptidase (S12 family) 0.0111 0.0384 0.0966
Echinococcus multilocularis sodium:glucose cotransporter 2 0.0039 0.0088 0.0083
Brugia malayi GTP-binding regulatory protein Gs alpha-S chain, putative 0.0391 0.1549 0.3937
Loa Loa (eye worm) histone methyltransferase 0.0037 0.0078 0.0198
Mycobacterium tuberculosis Phenyloxazoline synthase MbtB (phenyloxazoline synthetase) 0.0029 0.0046 0.0121
Loa Loa (eye worm) oxidoreductase 0.0029 0.0046 0.0116
Echinococcus granulosus histone lysine N methyltransferase MLL3 0.0037 0.0078 0.0187
Echinococcus granulosus Basic leucine zipper bZIP transcription 0.0221 0.0842 0.213
Trichomonas vaginalis conserved hypothetical protein 0.0026 0.0034 0.0168
Brugia malayi follicle stimulating hormone receptor 0.0932 0.3793 0.9645
Mycobacterium tuberculosis Probable oxidoreductase 0.0127 0.0451 0.1543
Trypanosoma cruzi mitogen-activated protein kinase 11, putative 0.0052 0.0143 0.1122
Schistosoma mansoni survival motor neuron protein 0.0149 0.0544 0.1373
Echinococcus multilocularis calcium:calmodulin dependent 3',5' cyclic 0.0045 0.0111 0.0106
Loa Loa (eye worm) hypothetical protein 0.0596 0.2399 0.6099
Brugia malayi MH1 domain containing protein 0.0033 0.0061 0.0155
Trichomonas vaginalis conserved hypothetical protein 0.0026 0.0034 0.0168
Brugia malayi CXXC zinc finger family protein 0.0116 0.0406 0.1032
Brugia malayi exodeoxyribonuclease III family protein 0.0021 0.0012 0.0029
Mycobacterium ulcerans hypothetical protein 0.015 0.0547 0.9589
Echinococcus granulosus tar DNA binding protein 0.02 0.0756 0.1914
Schistosoma mansoni tar DNA-binding protein 0.02 0.0756 0.1914
Echinococcus multilocularis peptidase Clp (S14 family) 0.0054 0.015 0.0145
Mycobacterium tuberculosis Probable aldehyde dehydrogenase 0.0072 0.0224 0.0747
Echinococcus multilocularis high affinity choline transporter 1 0.0356 0.1402 0.1398
Mycobacterium tuberculosis Probable aminotransferase 0.015 0.0547 0.188
Schistosoma mansoni nuclear hormone receptor superfamily protein-related 0.0059 0.0172 0.0426
Mycobacterium tuberculosis Probable fatty-acid-CoA ligase FadD5 (fatty-acid-CoA synthetase) (fatty-acid-CoA synthase) 0.007 0.0216 0.0718
Trypanosoma cruzi hypothetical protein, conserved 0.0036 0.0075 0.0541
Echinococcus multilocularis thioredoxin glutathione reductase 0.005 0.0133 0.0128
Plasmodium falciparum cGMP-specific phosphodiesterase 0.0045 0.0111 0.2639
Schistosoma mansoni camp-specific cyclic nucleotide phosphodiesterase 0.0045 0.0111 0.027
Echinococcus multilocularis lamin 0.0026 0.0034 0.0029
Echinococcus multilocularis solute carrier family 5 0.0039 0.0088 0.0083
Trypanosoma cruzi acetyl-CoA synthetase, putative 0.0029 0.0046 0.0295
Loa Loa (eye worm) hypothetical protein 0.0019 0.0005 0.0011
Trypanosoma cruzi cAMP-specific phosphodiesterase, putative 0.0045 0.0111 0.0848
Leishmania major mitogen activated protein kinase 4, putative;with=GeneDB:LmxM19.1440 0.0052 0.0143 0.1211
Loa Loa (eye worm) hypothetical protein 0.0059 0.0172 0.0436
Echinococcus granulosus GPCR family 2 0.0047 0.0121 0.0297
Onchocerca volvulus 0.0233 0.0891 0.6049
Trypanosoma cruzi long-chain-fatty-acid-CoA ligase, putative 0.0029 0.0046 0.0295
Loa Loa (eye worm) hypothetical protein 0.0059 0.0172 0.0436
Mycobacterium ulcerans fatty-acid-CoA ligase 0.0099 0.0337 0.5834
Toxoplasma gondii hypothetical protein 0.0028 0.0043 0.0321
Loa Loa (eye worm) hypothetical protein 0.0071 0.0218 0.0553
Echinococcus granulosus Nuclear hormone receptor HR96 0.0059 0.0172 0.0426
Loa Loa (eye worm) AMP-binding enzyme family protein 0.0029 0.0046 0.0116
Mycobacterium ulcerans acyl-CoA synthetase 0.0099 0.0337 0.5834
Toxoplasma gondii 3'5'-cyclic nucleotide phosphodiesterase domain-containing protein 0.0045 0.0111 0.1008
Brugia malayi nuclear receptor RXR 0.0059 0.0172 0.0436
Loa Loa (eye worm) MH1 domain-containing protein 0.0033 0.0061 0.0155
Trichomonas vaginalis cyclic nucleotide phosphodiesterase, putative 0.0341 0.1342 1
Loa Loa (eye worm) doublecortin family protein 0.0019 0.0005 0.0011
Echinococcus granulosus geminin 0.0525 0.2103 0.5343
Trichomonas vaginalis cGMP-dependent 3,5-cyclic phosphodiesterase, putative 0.0161 0.0591 0.4357
Brugia malayi Probable ClpP-like protease 0.0083 0.0268 0.0681
Trichomonas vaginalis high-affinity cGMP-specific 3,5-cyclic phosphodiesterase, putative 0.0161 0.0591 0.4357
Echinococcus multilocularis TGF beta signal transducer SmadC 0.0033 0.0061 0.0056
Trichomonas vaginalis calcium/calmodulin-dependent 3,5-cyclic nucleotide phosphodiesterase, putative 0.0045 0.0111 0.0743
Plasmodium vivax thioredoxin reductase, putative 0.005 0.0133 0.3184
Trypanosoma cruzi hypothetical protein, conserved 0.0045 0.0111 0.0848
Trichomonas vaginalis alpha-glucosidase, putative 0.0036 0.0075 0.0474
Plasmodium falciparum thioredoxin reductase 0.005 0.0133 0.3184
Toxoplasma gondii AMP-binding enzyme domain-containing protein 0.0029 0.0046 0.035
Toxoplasma gondii 3'5'-cyclic nucleotide phosphodiesterase domain-containing protein 0.0045 0.0111 0.1008
Loa Loa (eye worm) hypothetical protein 0.0049 0.0127 0.0321
Echinococcus multilocularis inositol monophosphatase 1 0.0039 0.0087 0.0082
Loa Loa (eye worm) hypothetical protein 0.0194 0.0729 0.1854
Mycobacterium tuberculosis P-hydroxybenzoyl-AMP ligase FadD22 0.0029 0.0046 0.0121
Trypanosoma cruzi hypothetical protein, conserved 0.0045 0.0111 0.0848
Echinococcus granulosus cAMP and cAMP inhibited cGMP 3'5' cyclic 0.038 0.1503 0.3813
Echinococcus multilocularis cpg binding protein 0.0124 0.0442 0.0437
Trichomonas vaginalis high-affinity cGMP-specific 3,5-cyclic phosphodiesterase, putative 0.0302 0.1178 0.8769
Trichomonas vaginalis alpha-glucosidase, putative 0.0036 0.0075 0.0474
Brugia malayi Ligand-binding domain of nuclear hormone receptor family protein 0.0126 0.0448 0.1139
Plasmodium vivax ATP-dependent Clp protease proteolytic subunit, putative 0.0083 0.0268 0.6564
Entamoeba histolytica glycosyl hydrolase, family 31 protein 0.0036 0.0075 0.076
Echinococcus granulosus Membrane bound O acyl transferase MBOAT 0.0083 0.0271 0.0676
Schistosoma mansoni nuclear receptor 2DBD-gamma 0.0126 0.0448 0.1129
Mycobacterium ulcerans beta-lactamase 0.0111 0.0384 0.6675
Trichomonas vaginalis calcium/calmodulin-dependent 3,5-cyclic nucleotide phosphodiesterase, putative 0.0302 0.1178 0.8769
Trichomonas vaginalis cone cGMP-specific 3,5-cyclic phosphodiesterase, putative 0.0302 0.1178 0.8769
Schistosoma mansoni cgmp-dependent 35-cyclic phosphodiesterase 0.025 0.0962 0.2436
Loa Loa (eye worm) hypothetical protein 0.0059 0.0172 0.0436
Trichomonas vaginalis conserved hypothetical protein 0.0257 0.0993 0.7375
Loa Loa (eye worm) nuclear receptor NHR-67 0.0059 0.0172 0.0436
Schistosoma mansoni high-affinity choline transporter 0.0356 0.1402 0.3557
Loa Loa (eye worm) hypothetical protein 0.0047 0.0121 0.0307
Echinococcus multilocularis Nuclear hormone receptor HR96 0.0059 0.0172 0.0167
Schistosoma mansoni FTZ-F1 nuclear receptor-like protein 0.0126 0.0448 0.1129
Loa Loa (eye worm) intermediate filament protein 0.0026 0.0034 0.0085
Onchocerca volvulus 0.0111 0.0384 0.2589
Trichomonas vaginalis high-affinity cGMP-specific 3,5-cyclic phosphodiesterase, putative 0.0302 0.1178 0.8769
Onchocerca volvulus 0.0026 0.0034 0.0199
Trichomonas vaginalis conserved hypothetical protein 0.0257 0.0993 0.7375
Trichomonas vaginalis penicillin-binding protein, putative 0.0111 0.0384 0.2799
Trichomonas vaginalis conserved hypothetical protein 0.0116 0.0406 0.2963
Onchocerca volvulus 0.0094 0.0315 0.2119
Brugia malayi Glycosyl hydrolases family 31 protein 0.0036 0.0075 0.0189
Trichomonas vaginalis conserved hypothetical protein 0.0026 0.0034 0.0168
Trichomonas vaginalis conserved hypothetical protein 0.0083 0.0271 0.1945
Brugia malayi steroid hormone receptor 0.0126 0.0448 0.1139
Giardia lamblia Kinase, CMGC MAPK 0.0052 0.0143 1
Brugia malayi nuclear hormone receptor family member nhr-6 0.0059 0.0172 0.0436
Entamoeba histolytica acyl-CoA synthetase, putative 0.0099 0.0337 0.3922
Loa Loa (eye worm) hypothetical protein 0.0067 0.0202 0.0511
Schistosoma mansoni Smad4 0.0033 0.0061 0.0144
Trypanosoma brucei protein kinase, putative 0.0052 0.0143 0.1122
Mycobacterium ulcerans non-ribosomal peptide synthetase MbtF 0.0029 0.0046 0.0616
Echinococcus multilocularis survival motor neuron protein 1 0.0731 0.2959 0.2955
Loa Loa (eye worm) TAR-binding protein 0.02 0.0756 0.1923
Toxoplasma gondii histone lysine methyltransferase SET1 0.0223 0.0851 0.8552
Echinococcus granulosus Nuclear hormone receptor family member nhr 41 0.0126 0.0448 0.1129
Trichomonas vaginalis inositol monophosphatase, putative 0.0039 0.0087 0.0566
Echinococcus granulosus zinc finger protein 0.0882 0.3587 0.9121
Trypanosoma brucei GAF domain/TIP41-like family, putative 0.0039 0.0089 0.0661
Loa Loa (eye worm) hypothetical protein 0.0038 0.0084 0.0213
Toxoplasma gondii hypothetical protein 0.0083 0.0271 0.2637
Echinococcus granulosus muscleblind protein 0.0596 0.2399 0.6095
Trypanosoma cruzi cAMP specific phosphodiesterase, putative 0.0302 0.1178 1
Loa Loa (eye worm) hypothetical protein 0.0126 0.0448 0.1139
Plasmodium falciparum phosphodiesterase delta, putative 0.0045 0.0111 0.2639
Brugia malayi latrophilin 2 splice variant baaae 0.0102 0.0349 0.0886
Brugia malayi acetyl-Coenzyme A synthetase 2 0.0029 0.0046 0.0116
Brugia malayi Hypothetical 52.5 kDa protein ZK945.1 in chromosome II, putative 0.0111 0.0384 0.0976
Loa Loa (eye worm) nuclear hormone receptor family member nhr-1 0.0126 0.0448 0.1139
Toxoplasma gondii 3'5'-cyclic nucleotide phosphodiesterase domain-containing protein 0.0045 0.0111 0.1008
Schistosoma mansoni ornithine--oxo-acid transaminase 0.0021 0.0014 0.0022
Trichomonas vaginalis cGMP-specific 3,5-cyclic phosphodiesterase, putative 0.0302 0.1178 0.8769
Onchocerca volvulus 0.0033 0.0063 0.0398
Schistosoma mansoni hypothetical protein 0.0047 0.0121 0.0297
Leishmania major glycerol uptake protein, putative 0.0083 0.0271 0.2296
Echinococcus multilocularis tumor protein p63 0.0751 0.3043 0.3039
Treponema pallidum alginate O-acetylation protein (algI) 0.0083 0.0271 1
Toxoplasma gondii hypothetical protein 0.0116 0.0406 0.4018
Mycobacterium tuberculosis Two component sensor histidine kinase DevS 0.0155 0.057 0.196
Loa Loa (eye worm) hypothetical protein 0.022 0.0836 0.2126
Loa Loa (eye worm) hypothetical protein 0.0099 0.0337 0.0857
Toxoplasma gondii 3'5'-cyclic nucleotide phosphodiesterase domain-containing protein 0.0045 0.0111 0.1008
Entamoeba histolytica hypothetical protein 0.0221 0.0842 1
Echinococcus multilocularis bromodomain adjacent to zinc finger domain 0.0066 0.02 0.0195
Echinococcus granulosus guanine nucleotide binding protein Gs subunit 0.0391 0.1549 0.3931
Schistosoma mansoni lipoxygenase 0.0054 0.0148 0.0365
Echinococcus multilocularis Basic leucine zipper (bZIP) transcription 0.0221 0.0842 0.0837
Mycobacterium ulcerans fusion of enoyl-CoA hydratase, EchA21 and lipase, LipE 0.0111 0.0384 0.6675
Loa Loa (eye worm) calcium/calmodulin-stimulated cyclic nucleotide phosphodiesterase 0.0045 0.0111 0.028
Trypanosoma cruzi glycerol uptake protein, putative 0.0083 0.0271 0.2218
Trichomonas vaginalis cGMP-specific 3,5-cyclic phosphodiesterase, putative 0.0302 0.1178 0.8769
Toxoplasma gondii histone lysine methyltransferase SET/SUV39 0.0032 0.0056 0.0452
Entamoeba histolytica vacuolar protein sorting 26 0.0083 0.0271 0.3118
Schistosoma mansoni histone-lysine n-methyltransferase setb1 0.0032 0.0056 0.0131
Schistosoma mansoni cpg binding protein 0.0124 0.0442 0.1112
Mycobacterium leprae conserved hypothetical protein 0.0111 0.0384 0.6951
Mycobacterium tuberculosis NADPH-dependent mycothiol reductase Mtr 0.005 0.0133 0.0424
Trichomonas vaginalis high-affinity cGMP-specific 3,5-cyclic phosphodiesterase, putative 0.0302 0.1178 0.8769
Plasmodium falciparum 3',5'-cyclic nucleotide phosphodiesterase, putative 0.0045 0.0111 0.2639
Loa Loa (eye worm) hypothetical protein 0.0596 0.2399 0.6099
Toxoplasma gondii 3'5'-cyclic nucleotide phosphodiesterase domain-containing protein 0.0045 0.0111 0.1008
Loa Loa (eye worm) hypothetical protein 0.0083 0.0271 0.0687
Echinococcus multilocularis Nuclear hormone receptor family member nhr 41 0.0126 0.0448 0.0444
Schistosoma mansoni inositol monophosphatase 0.0039 0.0087 0.021
Echinococcus multilocularis lamin dm0 0.0026 0.0034 0.0029
Echinococcus multilocularis high affinity cgmp specific 3' 5' cyclic 0.0045 0.0111 0.0106
Mycobacterium tuberculosis Probable L-lysine-epsilon aminotransferase Lat (L-lysine aminotransferase) (lysine 6-aminotransferase) 0.0021 0.0014 0.0006
Mycobacterium leprae ATP-dependent Clp protease proteolytic subunit 1 0.0028 0.0043 0.0558
Loa Loa (eye worm) glycosyl hydrolase family 31 protein 0.0036 0.0075 0.0189
Trichomonas vaginalis cGMP-dependent 3,5-cyclic phosphodiesterase, putative 0.0302 0.1178 0.8769
Mycobacterium ulcerans putative regulatory protein 0.0116 0.0406 0.7065
Mycobacterium leprae DIHYDROLIPOAMIDE DEHYDROGENASE LPD (LIPOAMIDE REDUCTASE (NADH)) (LIPOYL DEHYDROGENASE) (DIHYDROLIPOYL DEHYDROGENASE) (DIAPHORASE 0.0127 0.0451 0.8203
Brugia malayi 4-aminobutyrate aminotransferase, mitochondrial precursor 0.0021 0.0014 0.0033
Brugia malayi intermediate filament protein 0.0026 0.0034 0.0085
Schistosoma mansoni ap endonuclease 0.0021 0.0012 0.0018
Brugia malayi ecdysteroid receptor 0.0126 0.0448 0.1139
Loa Loa (eye worm) hypothetical protein 0.0019 0.0005 0.0011
Trichomonas vaginalis esterase, putative 0.0111 0.0384 0.2799
Loa Loa (eye worm) hypothetical protein 0.0059 0.0172 0.0436
Echinococcus multilocularis zinc finger protein 0.0026 0.0034 0.0029
Echinococcus multilocularis ecdysone induced protein 78C 0.0126 0.0448 0.0444
Trichomonas vaginalis conserved hypothetical protein 0.0083 0.0271 0.1945
Schistosoma mansoni zinc finger protein 0.0026 0.0034 0.0073
Leishmania major glycerol uptake protein, putative 0.0083 0.0271 0.2296
Brugia malayi AMP-binding enzyme family protein 0.0029 0.0046 0.0116
Mycobacterium ulcerans acyl-CoA synthetase 0.0029 0.0046 0.0616
Trypanosoma cruzi GUP1, putative 0.0083 0.0271 0.2218
Mycobacterium leprae PROBABLE ATP-DEPENDENT CLP PROTEASE PROTEOLYTIC SUBUNIT 1 CLPP1 (ENDOPEPTIDASE CLP) 0.0054 0.015 0.2558
Echinococcus granulosus nuclear receptor 2DBD gamma 0.0126 0.0448 0.1129
Trypanosoma cruzi hypothetical protein, conserved 0.0045 0.0111 0.0848
Loa Loa (eye worm) hypothetical protein 0.0039 0.0088 0.0223
Brugia malayi ecdysone receptor 0.0059 0.0172 0.0436
Mycobacterium ulcerans aldehyde dehydrogenase 0.0072 0.0224 0.3809
Schistosoma mansoni hypothetical protein 0.0021 0.0011 0.0015
Mycobacterium ulcerans 4-aminobutyrate aminotransferase 0.0021 0.0014 0.0031
Mycobacterium leprae PROBABLE NADH DEHYDROGENASE NDH 0.0114 0.0398 0.7213
Echinococcus multilocularis cAMP specific 3',5' cyclic phosphodiesterase 0.0045 0.0111 0.0106
Entamoeba histolytica myo-inositol monophosphatase, putative 0.0039 0.0087 0.0908
Mycobacterium ulcerans long-chain-fatty-acid--CoA ligase 0.0099 0.0337 0.5834
Trichomonas vaginalis cAMP-specific phosphodiesterase, putative 0.0302 0.1178 0.8769
Mycobacterium tuberculosis Probable dehydrogenase 0.0114 0.0398 0.1357
Trypanosoma brucei cAMP-specific phosphodiesterase 0.0302 0.1178 1
Schistosoma mansoni o-acyltransferase (membrane bound) domain containing protein 0.0083 0.0271 0.0676
Echinococcus granulosus intermediate filament protein 0.0026 0.0034 0.0074
Echinococcus granulosus high affinity cAMP specific 3'5' cyclic 0.0045 0.0111 0.027
Brugia malayi Nuclear hormone receptor family member nhr-25 0.0126 0.0448 0.1139
Schistosoma mansoni smad 0.0033 0.0061 0.0144
Onchocerca volvulus 0.0059 0.0172 0.114
Onchocerca volvulus 0.0029 0.0046 0.0282
Loa Loa (eye worm) hypoxia-induced factor 1 0.0159 0.0585 0.1488
Onchocerca volvulus 0.0099 0.0337 0.2268
Plasmodium vivax phosphodiesterase gamma, putative 0.0045 0.0111 0.2639
Brugia malayi hypothetical protein 0.0372 0.147 0.3738
Mycobacterium ulcerans lipase LipD 0.0111 0.0384 0.6675
Schistosoma mansoni hypothetical protein 0.0221 0.0842 0.213
Leishmania major hypothetical protein, conserved 0.0111 0.0384 0.3261
Echinococcus multilocularis dual 3',5' cyclic AMP and GMP phosphodiesterase 0.0302 0.1178 0.1174
Brugia malayi Hhat protein 0.0083 0.0271 0.0687
Brugia malayi photoreceptor-specific nuclear receptor 0.0126 0.0448 0.1139
Loa Loa (eye worm) thioredoxin reductase 0.005 0.0133 0.0336
Loa Loa (eye worm) nuclear hormone receptor family member nhr-14 0.0126 0.0448 0.1139
Mycobacterium tuberculosis Peptide synthetase MbtE (peptide synthase) 0.0029 0.0046 0.0121
Toxoplasma gondii acyl-CoA:diacylglycerol acyltransferase 1-related enzyme 0.0083 0.0271 0.2637
Echinococcus multilocularis aldehyde dehydrogenase, mitochondrial 0.0072 0.0224 0.022
Mycobacterium tuberculosis Two component sensor histidine kinase DosT 0.0116 0.0406 0.1385
Echinococcus granulosus 5'partial|histone lysine N methyltransferase SETDB2 0.0028 0.0041 0.0093
Trichomonas vaginalis conserved hypothetical protein 0.0026 0.0034 0.0168
Toxoplasma gondii 3'5'-cyclic nucleotide phosphodiesterase domain-containing protein 0.0045 0.0111 0.1008
Mycobacterium tuberculosis Conserved protein 0.0111 0.0384 0.1308
Echinococcus granulosus microtubule associated protein 2 0.0766 0.3103 0.7889
Chlamydia trachomatis ATP-dependent Clp protease proteolytic subunit 0.0083 0.0268 1
Echinococcus multilocularis retinoic acid receptor rxr beta a retinoic acid receptor rxr alpha a retinoic acid receptor rxr alpha 0.0059 0.0172 0.0167
Loa Loa (eye worm) hypothetical protein 0.0067 0.0202 0.0511
Loa Loa (eye worm) inositol-1 0.0039 0.0087 0.022
Plasmodium vivax AP endonuclease (DNA-[apurinic or apyrimidinic site] lyase), putative 0.0021 0.0012 0.0174
Schistosoma mansoni niemann-pick C1 (NPC1) 0.0105 0.0359 0.0903
Trichomonas vaginalis calcium/calmodulin-dependent 3,5-cyclic nucleotide phosphodiesterase, putative 0.0302 0.1178 0.8769
Entamoeba histolytica membrane-bound O-acyltransferase (MBOAT ) family protein 0.0083 0.0271 0.3118
Loa Loa (eye worm) CMGC/MAPK/ERK1 protein kinase 0.0052 0.0143 0.0362
Schistosoma mansoni thyroid hormone receptor 0.0126 0.0448 0.1129
Trichomonas vaginalis cGMP-inhibited 3,5-cyclic phosphodiesterase, putative 0.0045 0.0111 0.0743
Echinococcus multilocularis o acyltransferase (membrane bound) domain 0.0083 0.0271 0.0266
Loa Loa (eye worm) hypothetical protein 0.0356 0.1402 0.3564
Loa Loa (eye worm) hypothetical protein 0.0111 0.0384 0.0976
Mycobacterium tuberculosis Conserved protein 0.0111 0.0384 0.1308
Entamoeba histolytica Niemann-Pick C1 protein, putative 0.0103 0.0353 0.4109
Onchocerca volvulus Protein ultraspiracle homolog 0.0126 0.0448 0.3026
Loa Loa (eye worm) hypothetical protein 0.0731 0.2959 0.7523
Brugia malayi beta-lactamase 0.0111 0.0384 0.0976
Echinococcus multilocularis dnaJ subfamily B 0.0827 0.3357 0.3354
Echinococcus granulosus guanine nucleotide binding protein Gs subunit 0.0391 0.1549 0.3931
Schistosoma mansoni Tr4/Tr2 (homologue) 0.0126 0.0448 0.1129
Loa Loa (eye worm) hypothetical protein 0.0111 0.0384 0.0976
Plasmodium falciparum diacylglycerol O-acyltransferase 0.0083 0.0271 0.6624
Trichomonas vaginalis maltase-glucoamylase, putative 0.0036 0.0075 0.0474
Trichomonas vaginalis cyclic nucleotide phosphodiesterase, putative 0.0302 0.1178 0.8769
Leishmania major hypothetical protein, conserved 0.0039 0.0089 0.0755
Mycobacterium leprae PROBABLE ADENOSYLMETHIONINE-8-AMINO-7-OXONONANOATE AMINOTRANSFERASE BIOA 0.015 0.0547 1
Onchocerca volvulus 0.0032 0.0056 0.035
Trichomonas vaginalis cone cGMP-specific 3,5-cyclic phosphodiesterase, putative 0.0302 0.1178 0.8769
Loa Loa (eye worm) hypothetical protein 0.0372 0.147 0.3738
Brugia malayi AMP-binding enzyme family protein 0.0099 0.0337 0.0857
Leishmania major cAMP phosphodiesterase A, putative;with=GeneDB:LinJ18_V3.1100 0.0045 0.0111 0.094
Entamoeba histolytica glycosyl hydrolase, family 31 protein 0.0036 0.0075 0.076
Echinococcus multilocularis beta LACTamase domain containing family member 0.0111 0.0384 0.038
Plasmodium vivax acetyl-CoA synthetase, putative 0.0029 0.0046 0.1031
Trichomonas vaginalis cAMP/cGMP cyclic nucleotide phosphodiesterase, putative 0.0302 0.1178 0.8769
Mycobacterium tuberculosis Possible penicillin-binding protein 0.0707 0.2858 1
Plasmodium falciparum GAF domain-related protein, putative 0.0116 0.0406 1
Mycobacterium tuberculosis PROBABLE FATTY-ACID-CoA LIGASE FADD18 (FRAGMENT) (FATTY-ACID-CoA SYNTHETASE) (FATTY-ACID-CoA SYNTHASE) 0.0025 0.0029 0.0062
Echinococcus multilocularis nuclear receptor subfamily 4 group A 0.0059 0.0172 0.0167
Echinococcus granulosus mitogen activated protein kinase 0.0052 0.0143 0.0351
Trichomonas vaginalis chromodomain helicase DNA binding protein, putative 0.0026 0.0034 0.0168
Schistosoma mansoni retinoic acid receptor RXR 0.0126 0.0448 0.1129
Onchocerca volvulus Bile acid receptor homolog 0.0126 0.0448 0.3026
Trypanosoma cruzi hypothetical protein, conserved 0.0045 0.0111 0.0848
Mycobacterium ulcerans adenosylmethionine-8-amino-7-oxononanoate aminotransferase 0.015 0.0547 0.9589
Loa Loa (eye worm) nuclear Hormone Receptor family member 0.0126 0.0448 0.1139
Brugia malayi AMP-binding enzyme family protein 0.0099 0.0337 0.0857
Trichomonas vaginalis D-aminoacylase, putative 0.0111 0.0384 0.2799
Echinococcus granulosus beta LACTamase domain containing family member 0.0111 0.0384 0.0966
Leishmania major trypanothione reductase 0.005 0.0133 0.1125
Plasmodium falciparum phosphodiesterase gamma, putative 0.0045 0.0111 0.2639
Schistosoma mansoni nuclear receptor nhr-48 0.0059 0.0172 0.0426
Loa Loa (eye worm) pigment dispersing factor receptor c 0.0149 0.0545 0.1385
Loa Loa (eye worm) nuclear hormone receptor family member nhr-40 0.0126 0.0448 0.1139
Onchocerca volvulus Huntingtin homolog 0.0372 0.147 1
Echinococcus granulosus Aminotransferase class III 0.0021 0.0014 0.0022
Toxoplasma gondii hypothetical protein 0.0116 0.0406 0.4018
Trichomonas vaginalis conserved hypothetical protein 0.0045 0.0111 0.0743
Echinococcus multilocularis COUP TF:Svp nuclear hormone receptor 0.0126 0.0448 0.0444
Loa Loa (eye worm) hhat protein 0.0083 0.0271 0.0687
Brugia malayi Sodium:solute symporter family protein 0.0039 0.0088 0.0223
Plasmodium vivax ATP-dependent Clp protease proteolytic subunit, putative 0.0028 0.0043 0.096
Echinococcus multilocularis nuclear receptor 2DBD gamma 0.0126 0.0448 0.0444
Loa Loa (eye worm) hypothetical protein 0.0083 0.0271 0.0687
Loa Loa (eye worm) PHD-finger family protein 0.0021 0.0011 0.0026
Trypanosoma cruzi mitogen activated protein kinase 2, putative 0.0052 0.0143 0.1122
Mycobacterium ulcerans acyl-CoA synthetase 0.0029 0.0046 0.0616
Schistosoma mansoni hypothetical protein 0.0525 0.2103 0.5343
Echinococcus multilocularis muscleblind protein 0.0596 0.2399 0.2395
Echinococcus multilocularis ornithine aminotransferase 0.0021 0.0014 0.0009
Mycobacterium ulcerans fatty-acid-CoA ligase 0.0074 0.0233 0.3967
Mycobacterium tuberculosis Probable fatty-acid-CoA ligase FadD35 (fatty-acid-CoA synthetase) (fatty-acid-CoA synthase) 0.007 0.0216 0.0718
Brugia malayi RNA binding protein 0.02 0.0756 0.1923
Plasmodium falciparum ATP-dependent Clp protease proteolytic subunit 0.0083 0.0268 0.6564
Loa Loa (eye worm) MH2 domain-containing protein 0.0033 0.0061 0.0155
Schistosoma mansoni intermediate filament proteins 0.0026 0.0034 0.0074
Brugia malayi 3'5'-cyclic nucleotide phosphodiesterase family protein 0.0045 0.0111 0.028
Schistosoma mansoni membrane-bound acyltransferase/hhat 0.0083 0.0271 0.0676
Trypanosoma cruzi long-chain-fatty-acid-CoA ligase, putative 0.0029 0.0046 0.0295
Mycobacterium tuberculosis Probable lipase LipE 0.0111 0.0384 0.1308
Brugia malayi bHLH-PAS transcription factor 0.0038 0.0083 0.021
Trichomonas vaginalis rod cGMP-specific 3,5-cyclic phosphodiesterase, putative 0.0341 0.1342 1
Brugia malayi nuclear hormone receptor 0.0059 0.0172 0.0436
Trypanosoma cruzi cAMP specific phosphodiesterase, putative 0.0186 0.0698 0.5879
Leishmania major 4-coumarate:coa ligase-like protein 0.0099 0.0337 0.2863
Loa Loa (eye worm) hypothetical protein 0.0059 0.0172 0.0436
Brugia malayi Nuclear hormone receptor family member nhr-41 0.0126 0.0448 0.1139
Brugia malayi tailless protein 0.0059 0.0172 0.0436
Brugia malayi AMP-binding enzyme family protein 0.0029 0.0046 0.0116
Plasmodium vivax cyclic nucleotide phosphodiesterase, putative 0.0045 0.0111 0.2639
Loa Loa (eye worm) nuclear hormone receptor family member nhr-31 0.0126 0.0448 0.1139
Echinococcus granulosus sterol regulatory element binding protein 0.0044 0.0109 0.0264
Schistosoma mansoni hypothetical protein 0.0827 0.3357 0.8536
Brugia malayi RNA recognition motif domain containing protein 0.02 0.0756 0.1923
Echinococcus multilocularis diacylglycerol O acyltransferase 1 0.0083 0.0271 0.0266
Mycobacterium ulcerans long-chain fatty-acid CoA ligase 0.0099 0.0337 0.5834
Plasmodium vivax acyl-CoA synthetase, putative 0.0074 0.0233 0.5691
Echinococcus granulosus nuclear receptor subfamily 4 group A 0.0059 0.0172 0.0426
Schistosoma mansoni lamin 0.0026 0.0034 0.0074
Echinococcus granulosus lamin 0.0026 0.0034 0.0074
Mycobacterium leprae POSSIBLE O-SUCCINYLBENZOIC ACID--CoA LIGASE MENE (OSB-CoA SYNTHETASE) (O-SUCCINYLBENZOATE-CoA SYNTHASE) 0.0029 0.0046 0.0612
Trypanosoma brucei glycerol uptake protein, putative 0.0083 0.0271 0.2218
Brugia malayi diacylglycerol acyltransferase 0.0083 0.0271 0.0687
Echinococcus multilocularis GPCR, family 2 0.0047 0.0121 0.0117
Schistosoma mansoni sodium/solute symporter 0.0039 0.0088 0.0212
Echinococcus multilocularis DNA (apurinic or apyrimidinic site) lyase 0.0021 0.0012 0.0007
Echinococcus multilocularis microtubule associated protein 2 0.0766 0.3103 0.31
Loa Loa (eye worm) hypothetical protein 0.0074 0.0233 0.0592
Echinococcus granulosus Niemann Pick C1 protein 0.0147 0.0536 0.1353
Loa Loa (eye worm) latrophilin receptor protein 2 0.0047 0.0121 0.0307
Trichomonas vaginalis D-aminoacylase, putative 0.0111 0.0384 0.2799
Schistosoma mansoni camp-specific 35-cyclic phosphodiesterase 0.0045 0.0111 0.027
Echinococcus multilocularis muscleblind protein 1 0.0596 0.2399 0.2395
Loa Loa (eye worm) hypothetical protein 0.0029 0.0046 0.0116
Brugia malayi Nuclear hormone receptor family member nhr-25 0.0126 0.0448 0.1139
Trichomonas vaginalis neutral alpha-glucosidase ab precursor, putative 0.0036 0.0075 0.0474
Mycobacterium tuberculosis Peptide synthetase MbtF (peptide synthase) 0.0029 0.0046 0.0121
Loa Loa (eye worm) hypothetical protein 0.0059 0.0172 0.0436
Mycobacterium leprae Probable fatty-acid-CoA synthetase FadD22 (fatty-acid-CoA ligase) (fatty-acid-CoA synthase) 0.0029 0.0046 0.0612
Schistosoma mansoni aryl hydrocarbon receptor 0.0051 0.0139 0.034
Echinococcus multilocularis protein cysteine N palmitoyltransferase 0.0966 0.3932 0.3929
Schistosoma mansoni hypothetical protein 0.0047 0.0121 0.0297
Trichomonas vaginalis chromodomain helicase DNA binding protein, putative 0.0026 0.0034 0.0168
Schistosoma mansoni transcription factor LCR-F1 0.0221 0.0842 0.213
Trichomonas vaginalis cAMP-specific phosphodiesterase, putative 0.0302 0.1178 0.8769
Trypanosoma cruzi cAMP specific phosphodiesterase, putative 0.0302 0.1178 1
Trichomonas vaginalis calcium/calmodulin-dependent 3',5'-cyclic nucleotide phosphodiesterase, putative 0.0045 0.0111 0.0743
Echinococcus multilocularis FTZ F1 alpha 0.0126 0.0448 0.0444
Trichomonas vaginalis high-affinity cGMP-specific 3,5-cyclic phosphodiesterase, putative 0.0084 0.0274 0.1974
Mycobacterium tuberculosis Probable acetylornithine aminotransferase ArgD 0.0021 0.0014 0.0006
Trypanosoma brucei glycerol uptake protein, putative 0.0083 0.0271 0.2218
Leishmania major aldehyde dehydrogenase, mitochondrial precursor 0.0072 0.0224 0.1904
Echinococcus multilocularis hepatocyte nuclear factor 4 alpha 0.0126 0.0448 0.0444
Trypanosoma cruzi GUP1, putative 0.0083 0.0271 0.2218
Trypanosoma cruzi GAF domain/TIP41-like family, putative 0.0039 0.0089 0.0661
Echinococcus multilocularis protein dispatched 1 0.005 0.0135 0.013
Schistosoma mansoni o-acyltransferase (membrane bound) domain containing protein 0.0083 0.0271 0.0676
Echinococcus multilocularis ATP dependent Clp protease proteolytic subunit 0.0083 0.0268 0.0263
Mycobacterium tuberculosis NAD(P)H quinone reductase LpdA 0.0127 0.0451 0.1543
Brugia malayi Glycosyl hydrolases family 31 protein 0.0163 0.06 0.1524
Brugia malayi PAS domain containing protein 0.0051 0.0139 0.0351
Echinococcus multilocularis geminin 0.0525 0.2103 0.21
Trichomonas vaginalis myo inositol monophosphatase, putative 0.0039 0.0087 0.0566
Echinococcus granulosus mixed lineage leukemia protein mll 0.003 0.0049 0.0113
Trichomonas vaginalis cGMP-inhibited 3,5-cyclic phosphodiesterase, putative 0.0302 0.1178 0.8769
Brugia malayi Niemann-Pick C1 protein precursor 0.0103 0.0353 0.0896
Echinococcus multilocularis mitogen activated protein kinase 3 0.0052 0.0143 0.0138
Brugia malayi AMP-binding enzyme family protein 0.0029 0.0046 0.0116
Echinococcus granulosus cpg binding protein 0.0124 0.0442 0.1112
Trichomonas vaginalis chromodomain helicase DNA binding protein, putative 0.0026 0.0034 0.0168
Loa Loa (eye worm) hypothetical protein 0.0126 0.0448 0.1139
Leishmania major hypothetical protein, conserved 0.0045 0.0111 0.094
Trichomonas vaginalis antibiotic synthetase, putative 0.0029 0.0046 0.0258
Loa Loa (eye worm) hypothetical protein 0.0335 0.1317 0.3348
Echinococcus multilocularis cAMP and cAMP inhibited cGMP 3',5' cyclic 0.038 0.1503 0.1498
Loa Loa (eye worm) Smad1 0.0033 0.0061 0.0155
Echinococcus granulosus sterol O acyltransferase 1 0.0083 0.0271 0.0676
Trypanosoma brucei 3', 5'-cyclic nucleotide phosphodiesterase, putative 0.0045 0.0111 0.0848
Toxoplasma gondii thioredoxin reductase 0.005 0.0133 0.1231
Echinococcus granulosus diacylglycerol O acyltransferase 1 0.0083 0.0271 0.0676
Entamoeba histolytica hypothetical protein, conserved 0.0083 0.0271 0.3118
Wolbachia endosymbiont of Brugia malayi acetylornithine transaminase protein 0.0021 0.0014 0.0068
Brugia malayi nuclear receptor RXR 0.0067 0.0202 0.0511
Trichomonas vaginalis alpha-glucosidase, putative 0.0036 0.0075 0.0474
Trypanosoma cruzi hypothetical protein, conserved 0.0045 0.0111 0.0848
Trypanosoma cruzi myo-inositol-1(or 4)-monophosphatase 1, putative 0.0039 0.0087 0.0646
Brugia malayi hypothetical protein 0.0221 0.0842 0.2139
Brugia malayi hypothetical protein 0.0059 0.0172 0.0436
Echinococcus multilocularis Membrane bound O acyl transferase, MBOAT 0.0083 0.0271 0.0266
Echinococcus granulosus zinc finger protein 0.0026 0.0034 0.0073
Leishmania major glycerol uptake protein, putative 0.0083 0.0271 0.2296
Echinococcus granulosus o acyltransferase membrane bound domain 0.0083 0.0271 0.0676
Schistosoma mansoni camp-specific 35-cyclic phosphodiesterase 0.0045 0.0111 0.027
Schistosoma mansoni hepatocyte nuclear factor 4-alpha (hnf-4-alpha) 0.0059 0.0172 0.0426
Echinococcus granulosus nuclear receptor subfamily 1 group D 0.0067 0.0202 0.0501
Brugia malayi Probable 3',5'-cyclic phosphodiesterase R153.1, putative 0.0045 0.0111 0.028
Toxoplasma gondii 3'5'-cyclic nucleotide phosphodiesterase domain-containing protein 0.0045 0.0111 0.1008
Schistosoma mansoni high-affinity cgmp-specific 35-cyclic phosphodiesterase 0.0045 0.0111 0.027
Brugia malayi orphan nuclear receptor NR2E1 0.0059 0.0172 0.0436
Trypanosoma cruzi cAMP phosphodiesterase A, putative 0.0045 0.0111 0.0848
Toxoplasma gondii CMGC kinase, MAPK family (ERK) MAPK-1 0.0052 0.0143 0.1334
Echinococcus granulosus neutral alpha glucosidase AB 0.0036 0.0075 0.0178
Brugia malayi AMP-binding enzyme family protein 0.0099 0.0337 0.0857
Brugia malayi Nuclear hormone receptor-like 1 0.0067 0.0202 0.0511
Trichomonas vaginalis cGMP-dependent 3,5-cyclic phosphodiesterase, putative 0.0045 0.0111 0.0743
Schistosoma mansoni smad1 5 8 and 0.0033 0.0061 0.0144
Loa Loa (eye worm) hypothetical protein 0.0126 0.0448 0.1139
Giardia lamblia hypothetical protein 0.0045 0.0111 0.7557
Loa Loa (eye worm) hypothetical protein 0.0074 0.0233 0.0592
Leishmania major apurinic/apyrimidinic endonuclease-redox protein 0.0021 0.0012 0.0101
Mycobacterium tuberculosis Probable fatty-acid-CoA ligase FadD8 (fatty-acid-CoA synthetase) (fatty-acid-CoA synthase) 0.0029 0.0046 0.0121
Echinococcus granulosus sodium coupled monocarboxylate transporter 1 0.0039 0.0088 0.0212
Echinococcus multilocularis arachidonate 5 lipoxygenase 0.0054 0.0148 0.0143
Brugia malayi hypothetical protein 0.0067 0.0202 0.0511
Trichomonas vaginalis conserved hypothetical protein 0.0026 0.0034 0.0168
Mycobacterium ulcerans L-lysine aminotransferase 0.0021 0.0014 0.0031
Toxoplasma gondii transporter, solute:sodium symporter (SSS) family protein 0.0039 0.0088 0.0777
Onchocerca volvulus Steroid hormone receptor family member cnr14 homolog 0.0126 0.0448 0.3026
Schistosoma mansoni inositol transporter 0.0039 0.0088 0.0212
Plasmodium vivax glutathione reductase, putative 0.005 0.0133 0.3184
Leishmania major myo-inositol-1(or 4)-monophosphatase 1, putative 0.0039 0.0087 0.074
Schistosoma mansoni cpg binding protein 0.0116 0.0406 0.1022
Mycobacterium ulcerans putative regulatory protein 0.0038 0.0083 0.1277
Loa Loa (eye worm) abnormal chemotaxis protein 14 0.0044 0.0109 0.0275
Brugia malayi nuclear receptor NHR-67 0.0059 0.0172 0.0436
Echinococcus multilocularis diuretic hormone 44 receptor GPRdih2 0.0047 0.0121 0.0117
Schistosoma mansoni hypothetical protein 0.0525 0.2103 0.5343
Echinococcus multilocularis lysophospholipid acyltransferase 7 0.0083 0.0271 0.0266
Brugia malayi Nuclear hormone receptor-like 1 0.0067 0.0202 0.0511
Trypanosoma brucei hypothetical protein, conserved 0.0111 0.0384 0.3192
Loa Loa (eye worm) hypothetical protein 0.0126 0.0448 0.1139
Leishmania major acetyl-CoA synthetase, putative 0.0029 0.0046 0.0392
Schistosoma mansoni bromodomain containing protein 0.007 0.0215 0.0534
Mycobacterium tuberculosis Possible conserved lipoprotein LpqK 0.0111 0.0384 0.1308
Brugia malayi hypothetical protein 0.0019 0.0005 0.0011
Trypanosoma cruzi hypothetical protein, conserved 0.0111 0.0384 0.3192
Echinococcus granulosus o acyltransferase membrane bound domain 0.0083 0.0271 0.0676
Trypanosoma brucei long-chain-fatty-acid-CoA ligase, putative 0.0029 0.0046 0.0295
Echinococcus multilocularis nuclear receptor subfamily 1 group D 0.0067 0.0202 0.0197
Brugia malayi Pre-SET motif family protein 0.0205 0.0775 0.197
Loa Loa (eye worm) hypothetical protein 0.0149 0.0545 0.1385
Brugia malayi Steroid receptor seven-up type 2 0.0126 0.0448 0.1139
Trichomonas vaginalis acetylornithine aminotransferase, putative 0.015 0.0547 0.4021
Mycobacterium ulcerans acetyl-CoA synthetase 0.0029 0.0046 0.0616
Brugia malayi Doublecortin family protein 0.0019 0.0005 0.0011
Mycobacterium tuberculosis Probable fatty-acid-CoA ligase FadD3 (fatty-acid-CoA synthetase) (fatty-acid-CoA synthase) 0.007 0.0216 0.0718
Trypanosoma brucei trypanothione reductase 0.005 0.0133 0.1035
Loa Loa (eye worm) hypothetical protein 0.0059 0.0172 0.0436
Mycobacterium tuberculosis Probable ATP-dependent CLP protease proteolytic subunit 2 ClpP2 (endopeptidase CLP 2) 0.0054 0.015 0.0485
Loa Loa (eye worm) hypothetical protein 0.0372 0.147 0.3738
Schistosoma mansoni retinoid-x-receptor (RXR) 0.0126 0.0448 0.1129
Entamoeba histolytica acyl-coA synthetase, putative 0.0099 0.0337 0.3922
Brugia malayi nuclear hormone receptor family member odr-7 0.0059 0.0172 0.0436
Entamoeba histolytica long-chain-fatty-acid--CoA ligase, putative 0.0029 0.0046 0.0414
Toxoplasma gondii ATP-dependent Clp endopeptidase, proteolytic subunit ClpP domain-containing protein 0.0083 0.0268 0.2612
Mycobacterium ulcerans aldehyde dehydrogenase 0.0072 0.0224 0.3809
Leishmania major glycerol uptake protein, putative 0.0083 0.0271 0.2296
Echinococcus multilocularis neuropeptide receptor A26 0.0949 0.3863 0.386
Brugia malayi CHE-14 protein 0.0044 0.0109 0.0275
Brugia malayi hypoxia-induced factor 1 0.0159 0.0585 0.1488
Schistosoma mansoni mixed-lineage leukemia protein mll 0.0247 0.095 0.2406
Toxoplasma gondii glycosyl hydrolase, family 31 protein 0.0036 0.0075 0.0643
Schistosoma mansoni microtubule-associated protein tau 0.0766 0.3103 0.7889
Brugia malayi MBOAT family protein 0.0083 0.0271 0.0687
Echinococcus multilocularis ornithine aminotransferase 0.0021 0.0014 0.0009
Schistosoma mansoni Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) 0.0391 0.1549 0.3931
Trichomonas vaginalis conserved hypothetical protein 0.0026 0.0034 0.0168
Mycobacterium tuberculosis Probable membrane NADH dehydrogenase NdhA 0.0114 0.0398 0.1357
Mycobacterium tuberculosis Probable ornithine aminotransferase (N-terminus part) RocD1 (ornithine--oxo-acid aminotransferase) 0.0021 0.0014 0.0006
Echinococcus granulosus protein cysteine N palmitoyltransferase 0.0966 0.3932 1
Loa Loa (eye worm) beta-lactamase 0.0111 0.0384 0.0976
Schistosoma mansoni alpha glucosidase 0.0036 0.0075 0.0178
Mycobacterium tuberculosis Probable NADH dehydrogenase Ndh 0.0114 0.0398 0.1357
Mycobacterium leprae POSSIBLE FATTY-ACID-CoA LIGASE FADD10 (FATTY-ACID-CoA SYNTHETASE) (FATTY-ACID-CoA SYNTHASE) 0.0029 0.0046 0.0612
Schistosoma mansoni tar DNA-binding protein 0.02 0.0756 0.1914
Loa Loa (eye worm) nuclear hormone receptor-like 1 0.0067 0.0202 0.0511
Brugia malayi Nuclear hormone receptor family member nhr-19 0.0126 0.0448 0.1139
Plasmodium vivax ornithine aminotransferase, putative 0.0021 0.0014 0.0218
Loa Loa (eye worm) MBOAT family protein 0.0083 0.0271 0.0687
Loa Loa (eye worm) hypothetical protein 0.0074 0.0233 0.0592
Trichomonas vaginalis conserved hypothetical protein 0.0045 0.0111 0.0743
Brugia malayi Nuclear hormone receptor family member nhr-19 0.0126 0.0448 0.1139
Loa Loa (eye worm) hypothetical protein 0.0059 0.0172 0.0436
Schistosoma mansoni inositol transporter 0.0039 0.0088 0.0212
Echinococcus multilocularis bromodomain adjacent to zinc finger domain 0.0036 0.0074 0.0069
Loa Loa (eye worm) hypothetical protein 0.0172 0.0641 0.1629
Brugia malayi Nuclear hormone receptor E75 0.0059 0.0172 0.0436
Schistosoma mansoni patched 1 0.0044 0.0109 0.0264
Trichomonas vaginalis chromodomain-helicase-DNA-binding protein, putative 0.0026 0.0034 0.0168
Mycobacterium ulcerans ornithine aminotransferase RocD1 and RocD2 0.0021 0.0014 0.0031
Mycobacterium tuberculosis Probable peptide synthetase Nrp (peptide synthase) 0.0029 0.0046 0.0121
Treponema pallidum ATP-dependent Clp protease proteolytic subunit 0.0083 0.0268 0.9906
Onchocerca volvulus 0.0029 0.0046 0.0282
Schistosoma mansoni Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) 0.0391 0.1549 0.3931
Mycobacterium tuberculosis Dihydrolipoamide dehydrogenase LpdC (lipoamide reductase (NADH)) (lipoyl dehydrogenase) (dihydrolipoyl dehydrogenase) (diaphoras 0.0127 0.0451 0.1543
Loa Loa (eye worm) hypothetical protein 0.0026 0.0032 0.008
Loa Loa (eye worm) hypothetical protein 0.0049 0.0129 0.0327
Loa Loa (eye worm) hypothetical protein 0.0126 0.0448 0.1139
Mycobacterium tuberculosis Probable lipase LipD 0.0111 0.0384 0.1308
Schistosoma mansoni diacylglycerol O-acyltransferase 1 0.0083 0.0271 0.0676
Schistosoma mansoni nuclear receptor 0.0059 0.0172 0.0426
Brugia malayi nuclear hormone receptor 0.0126 0.0448 0.1139
Trichomonas vaginalis D-aminoacylase, putative 0.0111 0.0384 0.2799
Onchocerca volvulus 0.0126 0.0448 0.3026
Loa Loa (eye worm) MBOAT family protein 0.0083 0.0271 0.0687
Echinococcus multilocularis smad 0.0033 0.0061 0.0056
Schistosoma mansoni sterol O-acyltransferase 1 0.0083 0.0271 0.0676
Trichomonas vaginalis conserved hypothetical protein 0.0026 0.0034 0.0168
Loa Loa (eye worm) follicle stimulating hormone receptor 0.0932 0.3793 0.9645
Wolbachia endosymbiont of Brugia malayi fructose-1,6-bisphosphatase 0.0039 0.0087 0.2939
Toxoplasma gondii 3'5'-cyclic nucleotide phosphodiesterase domain-containing protein 0.0045 0.0111 0.1008
Loa Loa (eye worm) hypothetical protein 0.0041 0.0094 0.0238
Trichomonas vaginalis chromodomain helicase DNA binding protein, putative 0.0026 0.0034 0.0168
Echinococcus multilocularis thyroid hormone receptor alpha 0.0126 0.0448 0.0444
Brugia malayi Thioredoxin reductase 0.005 0.0133 0.0336
Loa Loa (eye worm) GTP-binding regulatory protein Gs alpha-S chain 0.0391 0.1549 0.3937
Mycobacterium tuberculosis Fatty-acid-AMP ligase FadD30 (fatty-acid-AMP synthetase) (fatty-acid-AMP synthase) 0.0074 0.0233 0.0778
Loa Loa (eye worm) hypothetical protein 0.0111 0.0384 0.0976
Onchocerca volvulus 0.0039 0.0088 0.0568
Brugia malayi MBOAT family protein 0.0083 0.0271 0.0687
Loa Loa (eye worm) nuclear hormone receptor 0.0059 0.0172 0.0436
Echinococcus granulosus hepatocyte nuclear factor 4 alpha 0.0126 0.0448 0.1129
Echinococcus multilocularis protein patched 0.0044 0.0109 0.0104
Mycobacterium ulcerans acetylornithine aminotransferase 0.0021 0.0014 0.0031
Echinococcus multilocularis sodium coupled monocarboxylate transporter 1 0.0039 0.0088 0.0083
Loa Loa (eye worm) hypothetical protein 0.0026 0.0034 0.0085
Chlamydia trachomatis acylglycerophosphoethanolamine acyltransferase 0.0074 0.0233 0.8625
Trichomonas vaginalis conserved hypothetical protein 0.0026 0.0034 0.0168
Trichomonas vaginalis high-affinity cGMP-specific 3,5-cyclic phosphodiesterase, putative 0.0045 0.0111 0.0743
Schistosoma mansoni tar DNA-binding protein 0.02 0.0756 0.1914
Toxoplasma gondii propionate-CoA ligase 0.0029 0.0046 0.035
Echinococcus granulosus solute carrier family 5 0.0039 0.0088 0.0212
Mycobacterium leprae possible inositol monophosphatase SubH (IMPase) (inositol-1-phosphatase) (I-1-Pase ). 0.0035 0.007 0.1062
Echinococcus multilocularis FTZ F1 nuclear receptor protein 0.0126 0.0448 0.0444
Echinococcus multilocularis histone lysine methyltransferase setb histone lysine methyltransferase eggless 0.0049 0.0127 0.0122
Brugia malayi hypothetical protein 0.0019 0.0005 0.0011
Brugia malayi Nuclear hormone receptor family member nhr-40 0.0126 0.0448 0.1139
Mycobacterium ulcerans O-succinylbenzoic acid--CoA ligase 0.0029 0.0046 0.0616
Echinococcus granulosus bromodomain adjacent to zinc finger domain 0.0066 0.02 0.0496
Onchocerca volvulus 0.0116 0.0406 0.2739
Brugia malayi oxidoreductase, short chain dehydrogenase/reductase family protein 0.0029 0.0046 0.0116
Mycobacterium ulcerans ATP-dependent Clp protease proteolytic subunit 0.0083 0.0268 0.4594
Trichomonas vaginalis myo inositol monophosphatase, putative 0.0039 0.0087 0.0566
Plasmodium vivax 3',5'-cyclic nucleotide phosphodiesterase, putative 0.0045 0.0111 0.2639
Echinococcus multilocularis fetal alzheimer antigen, falz 0.0029 0.0046 0.0041
Loa Loa (eye worm) pre-SET domain-containing protein family protein 0.0205 0.0775 0.197
Plasmodium falciparum AP endonuclease (DNA-[apurinic or apyrimidinic site] lyase), putative 0.0021 0.0012 0.0174
Schistosoma mansoni camp-specific 35-cyclic phosphodiesterase 0.0045 0.0111 0.027
Brugia malayi MBOAT family protein 0.0083 0.0271 0.0687
Toxoplasma gondii 3'5'-cyclic nucleotide phosphodiesterase domain-containing protein 0.0045 0.0111 0.1008
Plasmodium falciparum ornithine aminotransferase 0.0021 0.0014 0.0218
Mycobacterium tuberculosis Putative ferredoxin reductase 0.0114 0.0398 0.1357
Trypanosoma cruzi glycerol uptake protein, putative 0.0083 0.0271 0.2218
Giardia lamblia CAMP-specific 3,5-cyclic phosphodiesterase 4B 0.0045 0.0111 0.7557
Loa Loa (eye worm) MBOAT family protein 0.0966 0.3932 1
Echinococcus multilocularis guanine nucleotide binding protein G(s) subunit 0.0391 0.1549 0.1545
Trichomonas vaginalis set domain proteins, putative 0.0233 0.0891 0.6611
Loa Loa (eye worm) hypothetical protein 0.0054 0.015 0.038
Echinococcus multilocularis sterol regulatory element binding protein 0.0044 0.0109 0.0104
Leishmania major alpha glucosidase II subunit, putative 0.0036 0.0075 0.0636
Schistosoma mansoni zinc finger protein 0.0966 0.3932 1
Trichomonas vaginalis high-affinity cGMP-specific 3,5-cyclic phosphodiesterase, putative 0.0302 0.1178 0.8769
Loa Loa (eye worm) hypothetical protein 0.0045 0.0111 0.028
Trichomonas vaginalis chromodomain helicase DNA binding protein, putative 0.0026 0.0034 0.0168
Echinococcus granulosus diuretic hormone 44 receptor GPRdih2 0.0047 0.0121 0.0297
Schistosoma mansoni cellular tumor antigen P53 0.011 0.0382 0.0959
Echinococcus multilocularis cAMP specific 3',5' cyclic phosphodiesterase 0.0045 0.0111 0.0106
Trypanosoma brucei acetyl-CoA synthetase, putative 0.0029 0.0046 0.0295
Onchocerca volvulus 0.0059 0.0172 0.114
Schistosoma mansoni tar DNA-binding protein 0.02 0.0756 0.1914
Mycobacterium ulcerans non-ribosomal peptide synthetase MbtE 0.0029 0.0046 0.0616
Echinococcus granulosus Smad4 0.0033 0.0061 0.0144
Trichomonas vaginalis cyclic nucleotide phosphodiesterase, putative 0.0302 0.1178 0.8769
Mycobacterium ulcerans putative regulatory protein 0.0116 0.0406 0.7065
Echinococcus granulosus thioredoxin glutathione reductase 0.005 0.0133 0.0325
Echinococcus multilocularis mixed lineage leukemia protein mll 0.003 0.0049 0.0044
Echinococcus granulosus membrane bound acyltransferase:hhat 0.0083 0.0271 0.0676
Schistosoma mansoni TGF-beta signal transducer Smad2 0.0033 0.0061 0.0144
Loa Loa (eye worm) glycosyl hydrolase family 31 protein 0.0163 0.06 0.1524
Schistosoma mansoni hypothetical protein 0.0102 0.0349 0.0876
Onchocerca volvulus 0.0026 0.0034 0.0199
Echinococcus granulosus nuclear receptor 2DBD gamma 0.0059 0.0172 0.0426
Loa Loa (eye worm) hypothetical protein 0.0074 0.0233 0.0592
Toxoplasma gondii 3'5'-cyclic nucleotide phosphodiesterase domain-containing protein 0.0045 0.0111 0.1008
Trichomonas vaginalis CMGC family protein kinase 0.0052 0.0143 0.0984
Trichomonas vaginalis alpha-glucosidase, putative 0.0036 0.0075 0.0474
Plasmodium falciparum acyl-CoA synthetase 0.0074 0.0233 0.5691
Mycobacterium tuberculosis Probable glutamate-1-semialdehyde 2,1-aminomutase HemL (GSA) (glutamate-1-semialdehyde aminotransferase) (GSA-at) 0.0021 0.0014 0.0006
Loa Loa (eye worm) intermediate filament tail domain-containing protein 0.0026 0.0034 0.0085
Echinococcus granulosus dnaJ subfamily B 0.0827 0.3357 0.8536
Loa Loa (eye worm) membrane bound O-acyltransferase domain containing 1 0.0083 0.0271 0.0687
Toxoplasma gondii 3'5'-cyclic nucleotide phosphodiesterase domain-containing protein 0.0045 0.0111 0.1008
Echinococcus granulosus mitogen activated protein kinase 3 0.0052 0.0143 0.0351
Echinococcus granulosus survival motor neuron protein 1 0.0731 0.2959 0.752
Echinococcus granulosus calcium:calmodulin dependent 3'5' cyclic 0.0045 0.0111 0.027
Toxoplasma gondii 3'5'-cyclic nucleotide phosphodiesterase domain-containing protein 0.0045 0.0111 0.1008
Brugia malayi nuclear receptor subfamily 1, group D, member 1, putative 0.0059 0.0172 0.0436
Trichomonas vaginalis neutral alpha-glucosidase ab precursor, putative 0.0036 0.0075 0.0474
Mycobacterium ulcerans bifunctional enzyme MbtA: salicyl-AMP ligase (SAL-AMP ligase) + salicyl-S-ACP synthetase 0.0029 0.0046 0.0616
Brugia malayi MH1 domain containing protein 0.0033 0.0061 0.0155
Trichomonas vaginalis calcium/calmodulin-dependent 3,5-cyclic nucleotide phosphodiesterase, putative 0.0161 0.0591 0.4357
Mycobacterium ulcerans acyl-CoA synthetase 0.0099 0.0337 0.5834
Echinococcus multilocularis musashi 0.0026 0.0034 0.0029
Mycobacterium ulcerans aldehyde dehydrogenase 0.0072 0.0224 0.3809
Leishmania major cAMP-specific phosphodiesterase, putative 0.0045 0.0111 0.094
Leishmania major long-chain-fatty-acid-CoA ligase, putative 0.0029 0.0046 0.0392
Echinococcus multilocularis mitogen activated protein kinase 0.0052 0.0143 0.0138
Schistosoma mansoni high-affinity cgmp-specific 35-cyclic phosphodiesterase 0.0045 0.0111 0.027
Echinococcus granulosus thyroid hormone receptor alpha 0.0059 0.0172 0.0426
Trichomonas vaginalis cyclic nucleotide phosphodiesterase, putative 0.0045 0.0111 0.0743
Leishmania major 4-coumarate:coa ligase-like protein 0.0099 0.0337 0.2863
Treponema pallidum ATP-dependent Clp protease proteolytic subunit 0.0028 0.0043 0.1218
Plasmodium vivax SET domain protein, putative 0.0032 0.0056 0.1279
Trichomonas vaginalis high-affinity cGMP-specific 3,5-cyclic phosphodiesterase, putative 0.0084 0.0274 0.1974
Trichomonas vaginalis cAMP-specific 3,5-cyclic phosphodiesterase, putative 0.0302 0.1178 0.8769
Brugia malayi Pre-SET motif family protein 0.0032 0.0056 0.0142
Loa Loa (eye worm) hypothetical protein 0.0059 0.0172 0.0436
Trichomonas vaginalis CMGC family protein kinase 0.0052 0.0143 0.0984
Brugia malayi Muscleblind-like protein 0.0596 0.2399 0.6099
Trypanosoma cruzi mitogen-activated protein kinase 11, putative 0.0052 0.0143 0.1122
Mycobacterium leprae PROBABLE FATTY-ACID-CoA LIGASE FADD2 (FATTY-ACID-CoA SYNTHETASE) (FATTY-ACID-CoA SYNTHASE) 0.0099 0.0337 0.6071
Schistosoma mansoni nuclear hormone receptor 0.0059 0.0172 0.0426
Echinococcus multilocularis cadherin EGF LAG seven pass G type receptor 0.0047 0.0121 0.0117
Schistosoma mansoni inositol monophosphatase 0.0039 0.0087 0.021
Brugia malayi MH2 domain containing protein 0.0033 0.0061 0.0155
Leishmania major hypothetical protein, conserved 0.0083 0.0271 0.2296
Leishmania major 4-coumarate:coa ligase-like protein 0.0099 0.0337 0.2863
Trypanosoma cruzi hypothetical protein, conserved 0.0111 0.0384 0.3192
Mycobacterium ulcerans glutamate-1-semialdehyde aminotransferase 0.0021 0.0014 0.0031
Brugia malayi Nuclear hormone receptor family member nhr-49 0.0126 0.0448 0.1139
Onchocerca volvulus 0.0111 0.0384 0.2589
Trichomonas vaginalis cGMP-dependent 3,5-cyclic phosphodiesterase, putative 0.0302 0.1178 0.8769
Trichomonas vaginalis rod cGMP-specific 3,5-cyclic phosphodiesterase, putative 0.0302 0.1178 0.8769
Echinococcus granulosus histone lysine methyltransferase setb 0.0049 0.0127 0.031
Toxoplasma gondii ATP-dependent Clp endopeptidase, proteolytic subunit ClpP domain-containing protein 0.0083 0.0268 0.2612
Mycobacterium tuberculosis Inositol-1-monophosphatase SuhB 0.0035 0.007 0.0205
Loa Loa (eye worm) MH2 domain-containing protein 0.0481 0.1922 0.4888
Echinococcus multilocularis histone lysine N methyltransferase SETMAR 0.0032 0.0056 0.0051
Trichomonas vaginalis conserved hypothetical protein 0.0044 0.0109 0.0728
Brugia malayi Calcitonin receptor-like protein seb-1 0.0149 0.0545 0.1385
Brugia malayi hypothetical protein 0.0059 0.0172 0.0436
Trypanosoma brucei mitogen activated protein kinase 4, putative 0.0052 0.0143 0.1122
Brugia malayi beta-lactamase family protein 0.0111 0.0384 0.0976
Brugia malayi Nuclear hormone receptor family member nhr-31 0.0126 0.0448 0.1139
Mycobacterium ulcerans long-chain-acyl-CoA synthetase 0.0029 0.0046 0.0616
Brugia malayi Probable 3',5'-cyclic phosphodiesterase T04D3.3, putative 0.0045 0.0111 0.028
Echinococcus granulosus expressed conserved protein 0.0097 0.0327 0.082

Activities

Activity type Activity value Assay description Source Reference
EC50 (functional) > 30000 nM Beta-adrenergic agonistic activity of the compound was determined in guinea-pig atrium preincubated with phenoxybenzamine (12 uM) for 30 min ChEMBL. No reference
IC50 (functional) = 90 nM Beta-adrenergic agonistic activity of the compound was determined in rat proximal colon ChEMBL. No reference
IC50 (functional) = 185 nM Beta-adrenergic agonistic activity of the compound was determined in rat uterus preincubated with phenoxybenzamine (12 uM) for 30 min ChEMBL. No reference

Phenotypes

Whole-cell/tissue/organism interactions

We have no records of whole-cell/tissue assays done with this compound What does this mean?

Many chemical entities in TDR Targets come from high-throughput screenings with whole cells or tissue samples, and not all assayed compounds have been tested against a single a single target protein, probably because they get ruled out during screening process. Even if these compounds may have not been of interest in the original screening, they may come as interesting leads for other screening assays. Furthermore, we may be able to propose drug-target associations using chemical similarities and network patterns.

Annotated phenotypes:

We have no manually annotated phenotypes for this drug. What does this mean? / Care to help?
In TDR Targets, information about phenotypes that are caused by drugs, or by genetic manipulation of cells (e.g. gene knockouts or knockdowns) is manually curated from the literature. These descriptions help to describe the potential of the target for drug development. If no information is available for this gene or if the information is incomplete, this may mean that i) the papers containing this information either appeared after the curation effort for this organism was carried out or they were inadvertently missed by curators; or that ii) the curation effort for this organism has not yet started.
 
In any case, if you have information about papers containing relevant validation data for this target, please log in using your TDR Targets username and password and send them to us using the corresponding form in this page (only visible to registered users) or contact us.

External resources for this compound

Bibliographic References

No literature references available for this target.

If you have references for this compound, please enter them in a user comment (below) or Contact us.