Detailed information for compound 872633

Basic information

Technical information
  • TDR Targets ID: 872633
  • Name: 1-[6-(4-methylphenyl)imidazo[1,2-d][1,3,4]thi adiazol-2-yl]-N-[(3-methylphenyl)methyl]piper idine-4-carboxamide
  • MW: 445.58 | Formula: C25H27N5OS
  • H donors: 1 H acceptors: 3 LogP: 4.96 Rotable bonds: 6
    Rule of 5 violations (Lipinski): 1
  • SMILES: Cc1ccc(cc1)c1nc2n(c1)nc(s2)N1CCC(CC1)C(=O)NCc1cccc(c1)C
  • InChi: 1S/C25H27N5OS/c1-17-6-8-20(9-7-17)22-16-30-24(27-22)32-25(28-30)29-12-10-21(11-13-29)23(31)26-15-19-5-3-4-18(2)14-19/h3-9,14,16,21H,10-13,15H2,1-2H3,(H,26,31)
  • InChiKey: HMQZVZBMZMRVHN-UHFFFAOYSA-N  


Substructure search Similarity search

Network

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Synonyms

  • 1-[6-(4-methylphenyl)-2-imidazo[1,2-d][1,3,4]thiadiazolyl]-N-[(3-methylphenyl)methyl]-4-piperidinecarboxamide
  • N-(3-methylbenzyl)-1-[6-(4-methylphenyl)imidazo[1,2-d][1,3,4]thiadiazol-2-yl]isonipecotamide

Targets

Known targets for this compound

No curated genes were found associated with this compound

Predicted pathogen targets for this compound

By orthology
No druggable targets predicted by orthology data
By sequence similarity to non orthologous known druggable targets
No druggable targets predicted by sequence similarity
Obtained from network model

Ranking Plot

Putative Targets List

Species Potential target Raw Global Species
Brugia malayi C2-HC type zinc finger protein C.e-MyT1 0.0043 0.0013 0.0034
Loa Loa (eye worm) hypothetical protein 0.0054 0.0021 0.0056
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.3167 0.2334 1
Schistosoma mansoni biogenic amine (5HT) receptor 0.0049 0.0017 0.0046
Loa Loa (eye worm) hypothetical protein 0.0035 0.0007 0.0018
Entamoeba histolytica cysteine protease, putative 0.1705 0.1248 0.5344
Echinococcus granulosus tissue type plasminogen activator 0.0164 0.0103 0.0277
Loa Loa (eye worm) nuclear factor I 0.0101 0.0056 0.015
Giardia lamblia Cathepsin B precursor 0.0699 0.05 0.3345
Schistosoma mansoni jumonji/arid domain-containing protein 0.0047 0.0015 0.0041
Brugia malayi Pip kinase protein 2 0.0094 0.005 0.0135
Loa Loa (eye worm) heterotrimeric G protein alpha subunit 0.0035 0.0007 0.0018
Echinococcus multilocularis enteropeptidase 0.0244 0.0162 0.0436
Loa Loa (eye worm) matrixin family protein 0.1296 0.0944 0.2546
Brugia malayi hypothetical protein 0.0049 0.0017 0.0046
Schistosoma mansoni dipeptidyl-peptidase I (C01 family) 0.0914 0.066 0.1781
Schistosoma mansoni thyrotropin-releasing hormone receptor 0.0049 0.0017 0.0046
Onchocerca volvulus 0.3167 0.2334 1
Schistosoma mansoni opsin-like receptor 0.0049 0.0017 0.0046
Echinococcus granulosus 7tm_1 domain containing protein 0.0049 0.0017 0.0046
Leishmania major hypothetical protein, conserved 0.0201 0.013 0.0475
Trypanosoma cruzi PAB1-binding protein , putative 0.0201 0.013 0.0351
Brugia malayi angiogenesis inhibito 0.005 0.0017 0.0047
Loa Loa (eye worm) nuclear hormone receptor family member nhr-1 0.003 0.0003 0.0007
Toxoplasma gondii PAN domain-containing protein 0.0027 0.0001 0.0002
Toxoplasma gondii PAN domain-containing protein 0.0027 0.0001 0.0002
Echinococcus granulosus cadherin EGF LAG seven pass G type receptor 0.0698 0.0499 0.1347
Brugia malayi glutaminase DH11.1 0.0151 0.0093 0.025
Echinococcus multilocularis tissue type plasminogen activator 0.0164 0.0103 0.0277
Brugia malayi hypothetical protein 0.0049 0.0017 0.0046
Echinococcus multilocularis fibrillin 1 0.0056 0.0022 0.0059
Loa Loa (eye worm) hypothetical protein 0.0122 0.0071 0.0191
Schistosoma mansoni ancient conserved domain protein 2 (cyclin m2) 0.0049 0.0017 0.0046
Loa Loa (eye worm) hypothetical protein 0.0049 0.0017 0.0046
Schistosoma mansoni gcn5proteinral control of amino-acid synthesis 5-like 2 gcnl2 0.0106 0.0059 0.0159
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.1705 0.1248 0.5344
Giardia lamblia Dipeptidyl-peptidase I precursor 0.078 0.0561 0.3753
Echinococcus multilocularis subfamily S1A unassigned peptidase (S01 family) 0.0172 0.0108 0.0292
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.3712 0.274 1
Plasmodium falciparum serine repeat antigen 2 0.0699 0.05 0.2136
Brugia malayi Guanine nucleotide-binding protein alpha-3 subunit, putative 0.0035 0.0007 0.0018
Schistosoma mansoni photoreceptor-specific nuclear receptor related 0.003 0.0003 0.0007
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.3167 0.2334 1
Onchocerca volvulus 0.0038 0.0009 0.0036
Loa Loa (eye worm) guanine nucleotide-binding protein alpha-12 subunit 0.0035 0.0007 0.0018
Plasmodium falciparum cysteine repeat modular protein 1 0.0164 0.0103 0.0434
Echinococcus granulosus survival motor neuron protein 1 0.0169 0.0106 0.0287
Loa Loa (eye worm) cathepsin B 0.2033 0.1492 0.4024
Echinococcus granulosus glutathione S transferase 0.0049 0.0017 0.0046
Entamoeba histolytica papain family cysteine protease domain containing protein 0.0699 0.05 0.2141
Plasmodium vivax AP endonuclease (DNA-[apurinic or apyrimidinic site] lyase), putative 0.0043 0.0012 0.0033
Schistosoma mansoni hypothetical protein 0.0049 0.0017 0.0046
Trichomonas vaginalis Clan CA, family C1, papain-like cysteine peptidase 0.3167 0.2334 1
Loa Loa (eye worm) hypothetical protein 0.0172 0.0108 0.0292
Schistosoma mansoni GTP-binding protein (I) alpha-1subunit gnai1 0.0035 0.0007 0.0018
Schistosoma mansoni hypothetical protein 0.0035 0.0006 0.0017
Onchocerca volvulus Serine\/threonine kinase homolog 0.0053 0.002 0.0084
Trichomonas vaginalis Clan CA, family C1, cathepsin B-like cysteine peptidase 0.0833 0.0599 0.2567
Schistosoma mansoni GTP-binding protein (q) alpha-11 subunit gna11 0.0035 0.0007 0.0018
Echinococcus multilocularis musashi 0.0038 0.0009 0.0024
Onchocerca volvulus Neuropeptide F receptor homolog 0.0049 0.0017 0.0071
Loa Loa (eye worm) hypothetical protein 0.0051 0.0018 0.0049
Loa Loa (eye worm) hypothetical protein 0.0053 0.002 0.0053
Loa Loa (eye worm) exodeoxyribonuclease III family protein 0.0043 0.0012 0.0033
Entamoeba histolytica cysteine protease, putative 0.1705 0.1248 0.5344
Entamoeba histolytica cysteine protease, putative 0.1705 0.1248 0.5344
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.3167 0.2334 1
Echinococcus multilocularis cathepsin L cysteine protease 0.3167 0.2334 0.6299
Onchocerca volvulus 0.0049 0.0017 0.0071
Plasmodium vivax vivapain-2 0.3167 0.2334 1
Loa Loa (eye worm) papain family cysteine protease containing protein 0.3167 0.2334 0.6299
Echinococcus granulosus rhodopsin orphan GPCR 0.0049 0.0017 0.0046
Loa Loa (eye worm) glutathione reductase 0.0036 0.0007 0.0019
Toxoplasma gondii preprocathepsin c precursor, putative 0.0914 0.066 0.2828
Schistosoma mansoni alpha-1 adrenergic receptor 0.0049 0.0017 0.0046
Entamoeba histolytica cysteine protease, putative 0.0699 0.05 0.2141
Schistosoma mansoni GTP-binding protein (I) alpha subunit gnai 0.0035 0.0007 0.0018
Leishmania major cysteine peptidase A (CPA) 0.3167 0.2334 0.8522
Trypanosoma cruzi developmentally regulated phosphoprotein, putative 0.0271 0.0182 0.0492
Echinococcus granulosus regulator of G protein signaling 7 0.0034 0.0005 0.0015
Trypanosoma brucei apurinic/apyrimidinic endonuclease, putative 0.0043 0.0012 0.0045
Loa Loa (eye worm) hypothetical protein 0.5012 0.3706 1
Giardia lamblia Fructose-bisphosphate aldolase 0.0208 0.0135 0.0896
Echinococcus multilocularis transmembrane protease serine 3 0.0172 0.0108 0.0292
Loa Loa (eye worm) hypothetical protein 0.0101 0.0056 0.015
Echinococcus granulosus neuropeptide receptor A26 0.0049 0.0017 0.0046
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.3167 0.2334 1
Brugia malayi Bromodomain containing protein 0.0061 0.0026 0.0069
Loa Loa (eye worm) hypothetical protein 0.0049 0.0017 0.0046
Onchocerca volvulus 0.0172 0.0108 0.0461
Leishmania major DNA polymerase eta, putative 0.0038 0.0008 0.0031
Trichomonas vaginalis Clan CA, family C1, cathepsin B-like cysteine peptidase 0.2033 0.1492 0.6389
Echinococcus granulosus Peptidase S1 S6 chymotrypsin Hap 0.0172 0.0108 0.0292
Loa Loa (eye worm) hypothetical protein 0.003 0.0003 0.0007
Echinococcus multilocularis guanine nucleotide binding protein subunit 0.0035 0.0007 0.0018
Echinococcus granulosus Ataxin 2 N terminaldomain containing protein 0.009 0.0048 0.0129
Echinococcus multilocularis neuropeptide receptor A26 0.0049 0.0017 0.0046
Onchocerca volvulus 0.0049 0.0017 0.0071
Echinococcus granulosus Basic leucine zipper bZIP transcription 0.0119 0.0069 0.0187
Onchocerca volvulus 0.0035 0.0006 0.0024
Plasmodium vivax beta-hydroxyacyl-ACP dehydratase precursor, putative 0.0061 0.0026 0.009
Trichomonas vaginalis Clan CA, family C1, cathepsin H-like cysteine peptidase 0.0699 0.05 0.2141
Schistosoma mansoni alpha-glucosidase 0.0102 0.0056 0.0151
Trichomonas vaginalis Clan CA, family C1, cathepsin L or K-like cysteine peptidase 0.3167 0.2334 1
Echinococcus multilocularis allatostatin A receptor 0.0049 0.0017 0.0046
Echinococcus granulosus snurportin 1 0.0731 0.0524 0.1414
Echinococcus multilocularis DNA (apurinic or apyrimidinic site) lyase 0.0043 0.0012 0.0033
Giardia lamblia Cathepsin B precursor 0.0699 0.05 0.3345
Brugia malayi ADAMTS-like protease 0.005 0.0017 0.0047
Plasmodium vivax ATP-dependent Clp protease proteolytic subunit, putative 0.0042 0.0012 0.0031
Schistosoma mansoni transcription factor LCR-F1 0.0119 0.0069 0.0187
Echinococcus granulosus sex peptide receptor 0.0049 0.0017 0.0046
Schistosoma mansoni pyruvate dehydrogenase 0.0256 0.0171 0.0461
Onchocerca volvulus 0.0053 0.002 0.0082
Brugia malayi steroid hormone receptor 0.003 0.0003 0.0007
Loa Loa (eye worm) thioredoxin reductase 0.0036 0.0007 0.0019
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0699 0.05 0.2141
Echinococcus multilocularis growth hormone secretagogue receptor type 1 0.0049 0.0017 0.0046
Toxoplasma gondii cathepsin CPC1 0.0914 0.066 0.2828
Entamoeba histolytica cysteine protease, putative 0.3167 0.2334 1
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.3167 0.2334 1
Brugia malayi G-protein alpha subunit 0.0035 0.0007 0.0018
Loa Loa (eye worm) cysteine protease 0.3167 0.2334 0.6299
Loa Loa (eye worm) cytochrome P450 family protein 0.0027 0.0001 0.0002
Brugia malayi Iron-sulfur cluster assembly accessory protein 0.0035 0.0006 0.0017
Brugia malayi hypothetical protein 0.013 0.0077 0.0208
Trichomonas vaginalis Clan CA, family C1, papain-like cysteine peptidase 0.3167 0.2334 1
Toxoplasma gondii EGF family domain-containing protein 0.0053 0.002 0.0084
Echinococcus multilocularis protein jagged 2 0.0053 0.002 0.0053
Echinococcus multilocularis tm gpcr rhodopsin gpcr rhodopsin superfamily 0.0049 0.0017 0.0046
Brugia malayi Nuclear hormone receptor family member nhr-40 0.003 0.0003 0.0007
Echinococcus multilocularis tar DNA binding protein 0.0444 0.0311 0.0838
Brugia malayi PAN domain containing protein 0.0027 0.0001 0.0002
Loa Loa (eye worm) hypothetical protein 0.0053 0.002 0.0053
Loa Loa (eye worm) hypothetical protein 0.0035 0.0007 0.0018
Trichomonas vaginalis CAMK family protein kinase 0.0053 0.002 0.0086
Echinococcus granulosus bromodomain adjacent to zinc finger domain 0.0027 0 0.0001
Loa Loa (eye worm) hypothetical protein 0.0034 0.0006 0.0015
Mycobacterium ulcerans aldehyde dehydrogenase 0.0093 0.005 0.0822
Brugia malayi Ets-domain containing protein 0.0034 0.0006 0.0016
Echinococcus granulosus neuropeptide Y receptor 0.0049 0.0017 0.0046
Brugia malayi latrophilin 2 splice variant baaae 0.1507 0.1101 0.297
Echinococcus granulosus neurogenic locus notch protein 0.0053 0.002 0.0053
Schistosoma mansoni notch 0.0053 0.002 0.0053
Echinococcus multilocularis protein jagged 1 0.0053 0.002 0.0053
Trichomonas vaginalis GTP-binding protein (O) alpha subunit, gnao, putative 0.0035 0.0007 0.0029
Echinococcus multilocularis Pyruvate dehydrogenase (lipoamide) kinase 0.0271 0.0182 0.0492
Brugia malayi Papain family cysteine protease containing protein 0.1705 0.1248 0.3366
Schistosoma mansoni tar DNA-binding protein 0.0444 0.0311 0.0838
Brugia malayi Chymotrypsin-like protease CTRL-1 precursor 0.0172 0.0108 0.0292
Loa Loa (eye worm) guanine nucleotide-binding protein alpha-6 subunit 0.0035 0.0007 0.0018
Leishmania major trypanothione reductase 0.0036 0.0007 0.0026
Loa Loa (eye worm) hypothetical protein 0.0049 0.0017 0.0046
Echinococcus granulosus neuropeptide receptor 0.0049 0.0017 0.0046
Schistosoma mansoni subfamily S1A unassigned peptidase (S01 family) 0.0172 0.0108 0.0292
Echinococcus granulosus lamin dm0 0.0038 0.0009 0.0024
Echinococcus multilocularis nuclear receptor 2DBD gamma 0.003 0.0003 0.0007
Echinococcus granulosus Glutamate receptor ionotropic kainate 2 0.003 0.0002 0.0007
Onchocerca volvulus 0.0038 0.0009 0.0035
Brugia malayi G protein-coupled receptor 0.0049 0.0017 0.0046
Loa Loa (eye worm) G-protein-linked acetylcholine receptor protein 2 0.0049 0.0017 0.0046
Brugia malayi Latrophilin receptor protein 2 0.0698 0.0499 0.1347
Schistosoma mansoni biogenic amine receptor 0.0049 0.0017 0.0046
Schistosoma mansoni hypothetical protein 0.0172 0.0108 0.0292
Echinococcus multilocularis GA binding protein alpha chain 0.0034 0.0006 0.0016
Echinococcus multilocularis neuropeptides capa receptor 0.0049 0.0017 0.0046
Toxoplasma gondii 1,3(4)-beta-glucanase 0.0027 0.0001 0.0002
Echinococcus multilocularis neuropeptide Y receptor 0.0049 0.0017 0.0046
Schistosoma mansoni importin beta-1 0.0068 0.0031 0.0085
Echinococcus multilocularis tm gpcr rhodopsin gpcr rhodopsin superfamily 0.0049 0.0017 0.0046
Loa Loa (eye worm) hypothetical protein 0.1006 0.0728 0.1965
Onchocerca volvulus 0.0338 0.0232 0.0992
Entamoeba histolytica cysteine protease, putative 0.0699 0.05 0.2141
Loa Loa (eye worm) hypothetical protein 0.1507 0.1101 0.297
Echinococcus granulosus g protein linked acetylcholine receptor gar 2a 0.0049 0.0017 0.0046
Brugia malayi GnHR receptor homolog 0.0049 0.0017 0.0046
Echinococcus granulosus fmrfamide receptor 0.0049 0.0017 0.0046
Echinococcus multilocularis G protein coupled 5 hydroxytryptamine receptor 0.0049 0.0017 0.0046
Toxoplasma gondii calcium binding egf domain-containing protein 0.0051 0.0018 0.0078
Giardia lamblia Encystation-specific protease 0.078 0.0561 0.3753
Onchocerca volvulus 0.3167 0.2334 1
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0049 0.0017 0.0046
Loa Loa (eye worm) hypothetical protein 0.0049 0.0017 0.0046
Echinococcus granulosus geminin 0.0559 0.0396 0.1069
Trichomonas vaginalis importin beta-1, putative 0.0056 0.0022 0.0093
Echinococcus multilocularis guanine nucleotide binding protein G(s) subunit 0.082 0.059 0.1593
Plasmodium vivax glutathione reductase, putative 0.0036 0.0007 0.0011
Schistosoma mansoni hypothetical protein 0.0053 0.002 0.0053
Plasmodium falciparum cysteine proteinase falcipain 2b 0.3167 0.2334 1
Brugia malayi putative neuropeptide receptor NPR1 0.0049 0.0017 0.0046
Schistosoma mansoni hypothetical protein 0.1507 0.1101 0.297
Loa Loa (eye worm) notch protein 0.0053 0.002 0.0053
Giardia lamblia Cysteine protease 0.0699 0.05 0.3345
Brugia malayi MH2 domain containing protein 0.0183 0.0117 0.0315
Schistosoma mansoni neuropeptide receptor 0.0049 0.0017 0.0046
Echinococcus granulosus thyrotropin releasing hormone receptor 0.0049 0.0017 0.0046
Schistosoma mansoni myelin transcription factor 1 myt1 0.0043 0.0013 0.0034
Plasmodium falciparum serine repeat antigen 1 0.0699 0.05 0.2136
Brugia malayi sulfakinin receptor protein 0.0049 0.0017 0.0046
Schistosoma mansoni peptide (allatostatin/somatostatin)-like receptor 0.0049 0.0017 0.0046
Echinococcus granulosus neuropeptides capa receptor 0.0049 0.0017 0.0046
Trypanosoma brucei isocitrate dehydrogenase [NADP], mitochondrial precursor, putative 0.0169 0.0106 0.0388
Mycobacterium tuberculosis Probable aldehyde dehydrogenase 0.0093 0.005 0.0927
Schistosoma mansoni fyve finger-containing phosphoinositide kinase fyv1 0.0034 0.0005 0.0015
Echinococcus granulosus ATP dependent Clp protease proteolytic subunit 0.0122 0.0071 0.0191
Echinococcus granulosus cathepsin l cysteine peptidase 0.3167 0.2334 0.6299
Loa Loa (eye worm) hypothetical protein 0.0034 0.0005 0.0015
Echinococcus granulosus hypothetical protein 0.0049 0.0017 0.0046
Loa Loa (eye worm) hypothetical protein 0.1006 0.0728 0.1965
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0049 0.0017 0.0046
Echinococcus multilocularis cysteine protease 0.3167 0.2334 0.6299
Echinococcus granulosus somatostatin receptor 0.0049 0.0017 0.0046
Loa Loa (eye worm) neuropeptide F receptor 0.0049 0.0017 0.0046
Giardia lamblia Dipeptidyl-peptidase I precursor 0.0914 0.066 0.4422
Schistosoma mansoni cathepsin S (C01 family) 0.0699 0.05 0.1348
Loa Loa (eye worm) hypothetical protein 0.0068 0.0031 0.0085
Brugia malayi Dopamine receptor protein 1 0.0049 0.0017 0.0046
Brugia malayi Bromodomain containing protein 0.0031 0.0004 0.001
Echinococcus granulosus g protein coupled receptor 0.0049 0.0017 0.0046
Schistosoma mansoni peptide (allatostatin)-like receptor 0.0049 0.0017 0.0046
Echinococcus multilocularis segment polarity protein dishevelled 0.0034 0.0005 0.0015
Plasmodium vivax unspecified product 0.1006 0.0728 0.3106
Schistosoma mansoni tar DNA-binding protein 0.0444 0.0311 0.0838
Loa Loa (eye worm) MH2 domain-containing protein 0.2687 0.1978 0.5336
Schistosoma mansoni subfamily S1A unassigned peptidase (S01 family) 0.0244 0.0162 0.0436
Echinococcus multilocularis Pyruvate dehydrogenase (lipoamide) kinase 0.0271 0.0182 0.0492
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.3167 0.2334 1
Loa Loa (eye worm) hypothetical protein 0.1006 0.0728 0.1965
Echinococcus multilocularis matrix metallopeptidase 7 (M10 family) 0.1948 0.1429 0.3855
Brugia malayi Cathepsin L-like precursor 0.3167 0.2334 0.6299
Trichomonas vaginalis Clan CA, family C1, cathepsin F-like cysteine peptidase 0.0699 0.05 0.2141
Schistosoma mansoni cercarial elastase (S01 family) 0.0172 0.0108 0.0292
Echinococcus granulosus neurogenic locus notch protein 0.0053 0.002 0.0053
Brugia malayi Nuclear hormone receptor family member nhr-25 0.003 0.0003 0.0007
Schistosoma mansoni muscarinic acetylcholine (GAR) receptor 0.0049 0.0017 0.0046
Brugia malayi cathepsin F-like cysteine proteinase 0.1006 0.0728 0.1965
Echinococcus granulosus Glutamate receptor ionotropic kainate 2 0.003 0.0002 0.0007
Trypanosoma brucei isocitrate dehydrogenase, putative 0.0169 0.0106 0.0388
Echinococcus multilocularis guanine nucleotide binding protein (G protein) 0.0035 0.0007 0.0018
Echinococcus granulosus serotonin receptor 0.0049 0.0017 0.0046
Plasmodium falciparum ATP-dependent Clp protease proteolytic subunit 0.0042 0.0012 0.0044
Brugia malayi Unidentified vitellogenin-linked transcript protein 6, putative 0.0049 0.0017 0.0046
Echinococcus granulosus retinoic acid receptor rxr beta a 0.003 0.0003 0.0007
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0049 0.0017 0.0046
Onchocerca volvulus 0.0172 0.0108 0.0461
Trichomonas vaginalis CAMK family protein kinase 0.0026 0 0.0001
Brugia malayi Papain family cysteine protease containing protein 0.0699 0.05 0.1348
Echinococcus multilocularis dnaJ subfamily B 0.0304 0.0206 0.0557
Onchocerca volvulus Cathepsin L homolog 0.3167 0.2334 1
Loa Loa (eye worm) hypothetical protein 0.003 0.0003 0.0007
Onchocerca volvulus 0.0699 0.05 0.2139
Brugia malayi hypothetical protein 0.0049 0.0017 0.0046
Onchocerca volvulus 0.0172 0.0108 0.0461
Echinococcus granulosus dnaJ subfamily B 0.0304 0.0206 0.0557
Schistosoma mansoni subfamily S1A unassigned peptidase (S01 family) 0.0338 0.0232 0.0626
Giardia lamblia Cathepsin L precursor 0.0699 0.05 0.3345
Echinococcus multilocularis ecdysone induced protein 78C 0.003 0.0003 0.0007
Loa Loa (eye worm) hypothetical protein 0.0053 0.002 0.0053
Loa Loa (eye worm) hypothetical protein 0.0033 0.0005 0.0013
Echinococcus granulosus short transient receptor potential channel 6 0.0091 0.0048 0.0129
Loa Loa (eye worm) hypothetical protein 0.0049 0.0017 0.0046
Mycobacterium tuberculosis Probable ATP-dependent CLP protease proteolytic subunit 2 ClpP2 (endopeptidase CLP 2) 0.008 0.004 0.0714
Schistosoma mansoni Glutathione S-transferase 28 kDa (GST 28) (GST class-mu) 0.0281 0.0189 0.0511
Loa Loa (eye worm) hypothetical protein 0.0536 0.0379 0.1022
Schistosoma mansoni GTP-binding protein alpha subunit 0.0035 0.0007 0.0018
Loa Loa (eye worm) hypothetical protein 0.0053 0.002 0.0053
Loa Loa (eye worm) Papain cysteine protease/cathepsin propeptide inhibitor-containing protein 0.3167 0.2334 0.6299
Brugia malayi kinase, mitochondrial precursor 0.0271 0.0182 0.0492
Plasmodium vivax dipeptidyl aminopeptidase 1, putative 0.0914 0.066 0.2814
Loa Loa (eye worm) bone morphogenetic protein 1b 0.0051 0.0018 0.0049
Schistosoma mansoni glutathione-S-transferase 0.0064 0.0028 0.0075
Leishmania major hypothetical protein, conserved 0.0164 0.0103 0.0374
Echinococcus multilocularis gtp binding protein (I) alpha 1subunit 0.0035 0.0007 0.0018
Echinococcus multilocularis TRP (transient receptor potential) channel 0.0051 0.0018 0.005
Brugia malayi Calcium binding EGF domain containing protein 0.0053 0.002 0.0053
Echinococcus multilocularis rhodopsin orphan GPCR 0.0049 0.0017 0.0046
Loa Loa (eye worm) hypothetical protein 0.0049 0.0017 0.0046
Loa Loa (eye worm) hypothetical protein 0.0039 0.001 0.0027
Schistosoma mansoni tar DNA-binding protein 0.0444 0.0311 0.0838
Wolbachia endosymbiont of Brugia malayi ATP-dependent Clp protease proteolytic subunit 0.0122 0.0071 1
Toxoplasma gondii HEAT repeat-containing protein 0.0068 0.0031 0.0135
Schistosoma mansoni aldehyde dehydrogenase 0.0093 0.005 0.0134
Loa Loa (eye worm) hypothetical protein 0.0049 0.0017 0.0046
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0049 0.0017 0.0046
Loa Loa (eye worm) G protein alpha subunit 3 0.0035 0.0007 0.0018
Brugia malayi hypothetical protein 0.0049 0.0017 0.0046
Echinococcus multilocularis L aminoadipate semialdehyde 0.0062 0.0026 0.0071
Loa Loa (eye worm) CXXC zinc finger family protein 0.0045 0.0014 0.0037
Echinococcus granulosus neuropeptide s receptor 0.0049 0.0017 0.0046
Echinococcus granulosus dna polymerase eta 0.0038 0.0008 0.0023
Loa Loa (eye worm) hypothetical protein 0.0027 0.0001 0.0002
Brugia malayi serine/threonine-protein kinase plk-2 0.0053 0.002 0.0054
Echinococcus granulosus cathepsin l1 0.2161 0.1587 0.4281
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.3712 0.274 1
Loa Loa (eye worm) hypothetical protein 0.0049 0.0017 0.0046
Toxoplasma gondii beta-hydroxyacyl-acyl carrier protein dehydratase (FABZ) 0.0061 0.0026 0.0109
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.3167 0.2334 1
Echinococcus granulosus G protein coupled receptor 139 0.0049 0.0017 0.0046
Schistosoma mansoni tar DNA-binding protein 0.0444 0.0311 0.0838
Echinococcus multilocularis thyroid hormone receptor alpha 0.003 0.0003 0.0007
Schistosoma mansoni amine GPCR 0.0049 0.0017 0.0046
Echinococcus granulosus glutamate receptor 2 0.003 0.0002 0.0007
Loa Loa (eye worm) hypothetical protein 0.0033 0.0005 0.0013
Schistosoma mansoni GTP-binding protein (I) alpha-2 subunit gnai2 0.0035 0.0007 0.0018
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.1705 0.1248 0.4554
Echinococcus granulosus dro:myosuppressin receptor 0.0049 0.0017 0.0046
Echinococcus granulosus nuclear receptor 2DBD gamma 0.003 0.0003 0.0007
Schistosoma mansoni cercarial elastase (S01 family) 0.0172 0.0108 0.0292
Brugia malayi nuclear hormone receptor 0.003 0.0003 0.0007
Brugia malayi Thioredoxin reductase 0.0036 0.0007 0.0019
Loa Loa (eye worm) hypothetical protein 0.0038 0.0008 0.0023
Echinococcus granulosus guanine nucleotide binding protein subunit 0.0035 0.0007 0.0018
Loa Loa (eye worm) hypothetical protein 0.0188 0.012 0.0325
Trypanosoma cruzi isocitrate dehydrogenase [NADP], mitochondrial precursor, putative 0.0169 0.0106 0.0287
Loa Loa (eye worm) steroid hormone receptor 0.003 0.0003 0.0007
Entamoeba histolytica cysteine proteinase 2 0.1705 0.1248 0.5344
Trypanosoma brucei polo-like protein kinase 0.0053 0.002 0.0074
Echinococcus granulosus Smad4 0.0183 0.0117 0.0315
Schistosoma mansoni subfamily C1A non-peptidase homologue (C01 family) 0.0699 0.05 0.1348
Schistosoma mansoni gabp alpha 0.0034 0.0006 0.0016
Leishmania major cathepsin L-like protease 0.3167 0.2334 0.8522
Loa Loa (eye worm) hypothetical protein 0.0164 0.0103 0.0277
Brugia malayi Papain family cysteine protease containing protein 0.0699 0.05 0.1348
Trichomonas vaginalis fructose-bisphosphate aldolase, putative 0.0208 0.0135 0.0577
Loa Loa (eye worm) Sodium:neurotransmitter symporter family protein 0.0054 0.0021 0.0056
Brugia malayi Dopamine receptor protein 2 0.0049 0.0017 0.0046
Loa Loa (eye worm) hypothetical protein 0.0037 0.0008 0.0021
Trypanosoma brucei PAB1-binding protein , putative 0.0201 0.013 0.0475
Leishmania major cathepsin L-like protease 0.3712 0.274 1
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.3712 0.274 1
Echinococcus granulosus sodium and chloride dependent glycine 0.0054 0.0021 0.0056
Schistosoma mansoni Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) 0.082 0.059 0.1593
Loa Loa (eye worm) hypothetical protein 0.2161 0.1587 0.4281
Echinococcus granulosus segment polarity protein dishevelled 0.0034 0.0005 0.0015
Echinococcus multilocularis rhodopsin orphan GPCR 0.0049 0.0017 0.0046
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0699 0.05 0.2141
Loa Loa (eye worm) hypothetical protein 0.0049 0.0017 0.0046
Brugia malayi cahepsin L-like non-peptiedase homolog 0.0699 0.05 0.1348
Echinococcus granulosus matrix metallopeptidase 7 M10 family 0.1948 0.1429 0.3855
Schistosoma mansoni amine GPCR 0.0049 0.0017 0.0046
Toxoplasma gondii hypothetical protein 0.0042 0.0012 0.005
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0699 0.05 0.2141
Trichomonas vaginalis CAMK family protein kinase 0.0053 0.002 0.0086
Plasmodium falciparum serine repeat antigen 9 0.0699 0.05 0.2136
Loa Loa (eye worm) glycosyl hydrolase family 31 protein 0.0118 0.0068 0.0184
Echinococcus multilocularis TGF beta signal transducer SmadC 0.0183 0.0117 0.0315
Brugia malayi RE15519p 0.0049 0.0017 0.0046
Echinococcus multilocularis g-protein coupled receptor 0.0049 0.0017 0.0046
Brugia malayi MH2 domain containing protein 0.0183 0.0117 0.0315
Trichomonas vaginalis GTP-binding protein alpha subunit, gna, putative 0.0035 0.0007 0.0029
Schistosoma mansoni subfamily M12B unassigned peptidase (M12 family) 0.0032 0.0004 0.0012
Trichomonas vaginalis cat eye syndrome critical region protein 2, cscr2, putative 0.0032 0.0005 0.0019
Entamoeba histolytica hypothetical protein 0.0119 0.0069 0.0296
Echinococcus multilocularis glutathione S transferase 0.0064 0.0028 0.0075
Brugia malayi Nuclear hormone receptor family member nhr-19 0.003 0.0003 0.0007
Echinococcus granulosus cathepsin l1 0.3167 0.2334 0.6299
Loa Loa (eye worm) hypothetical protein 0.0034 0.0005 0.0015
Echinococcus granulosus notch 0.0053 0.002 0.0053
Schistosoma mansoni ets-related 0.0104 0.0058 0.0157
Echinococcus granulosus histone acetyltransferase MYST2 0.0043 0.0013 0.0034
Trypanosoma cruzi polo-like protein kinase, putative 0.0053 0.002 0.0054
Loa Loa (eye worm) hypothetical protein 0.0035 0.0007 0.0018
Plasmodium falciparum ataxin-2 like protein, putative 0.0201 0.013 0.0552
Echinococcus multilocularis gcn5proteinral control of amino acid synthesis 0.0106 0.0059 0.0159
Echinococcus granulosus prostaglandin H2 D isomerase 0.0281 0.0189 0.0511
Schistosoma mansoni hypothetical protein 0.0053 0.002 0.0053
Echinococcus multilocularis cathepsin L cysteine protease 0.3167 0.2334 0.6299
Schistosoma mansoni regulator of G protein signaling 0.0034 0.0005 0.0015
Echinococcus granulosus alpha 1A adrenergic receptor 0.0049 0.0017 0.0046
Loa Loa (eye worm) hypothetical protein 0.0053 0.002 0.0053
Echinococcus multilocularis adam 0.0067 0.003 0.0082
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.3167 0.2334 1
Brugia malayi EGF-like domain containing protein 0.0053 0.002 0.0053
Plasmodium falciparum cysteine proteinase falcipain 3 0.3167 0.2334 1
Brugia malayi Transient-receptor-potential like protein 0.0051 0.0018 0.005
Echinococcus granulosus histone acetyltransferase KAT2B 0.0032 0.0005 0.0012
Schistosoma mansoni coup transcription factor 0.003 0.0003 0.0007
Schistosoma mansoni hypothetical protein 0.0731 0.0524 0.1414
Echinococcus multilocularis prostaglandin H2 D isomerase 0.0281 0.0189 0.0511
Schistosoma mansoni amine GPCR 0.0049 0.0017 0.0046
Plasmodium vivax thioredoxin reductase, putative 0.0036 0.0007 0.0011
Schistosoma mansoni smad1 5 8 and 0.0183 0.0117 0.0315
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0049 0.0017 0.0046
Brugia malayi PAN domain containing protein 0.0027 0.0001 0.0002
Trypanosoma cruzi cysteine peptidase, putative 0.3712 0.274 0.7391
Mycobacterium leprae PROBABLE ATP-DEPENDENT CLP PROTEASE PROTEOLYTIC SUBUNIT 1 CLPP1 (ENDOPEPTIDASE CLP) 0.008 0.004 0.062
Echinococcus multilocularis Pleckstrin G protein, interacting region 0.0034 0.0005 0.0015
Trichomonas vaginalis CAMK family protein kinase 0.0053 0.002 0.0086
Echinococcus multilocularis sodium and chloride dependent glycine 0.0054 0.0021 0.0056
Loa Loa (eye worm) nuclear hormone receptor family member nhr-49 0.003 0.0003 0.0007
Echinococcus multilocularis pyroglutamylated rfamide peptide receptor 0.0049 0.0017 0.0046
Echinococcus multilocularis Glutamate receptor, ionotropic kainate 2 0.003 0.0002 0.0007
Schistosoma mansoni hypothetical protein 0.0049 0.0017 0.0046
Schistosoma mansoni nuclear receptor 2DBD-gamma 0.003 0.0003 0.0007
Loa Loa (eye worm) MBCTL1 0.0043 0.0013 0.0034
Entamoeba histolytica cysteine protease, putative 0.1705 0.1248 0.5344
Echinococcus granulosus serine:threonine protein kinase PLK1 0.0053 0.002 0.0054
Brugia malayi G-protein-linked acetylcholine receptor protein 2, putative 0.0049 0.0017 0.0046
Brugia malayi Nuclear hormone receptor family member nhr-3 0.003 0.0003 0.0007
Schistosoma mansoni FTZ-F1 nuclear receptor-like protein 0.003 0.0003 0.0007
Loa Loa (eye worm) hypothetical protein 0.0049 0.0017 0.0046
Echinococcus multilocularis dro:myosuppressin receptor 0.0049 0.0017 0.0046
Schistosoma mansoni glutamate receptor NMDA 0.0075 0.0036 0.0097
Echinococcus multilocularis neuropeptide s receptor 0.0049 0.0017 0.0046
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.3167 0.2334 1
Echinococcus multilocularis Glutamate receptor, ionotropic kainate 2 0.003 0.0002 0.0007
Schistosoma mansoni subfamily S1A unassigned peptidase (S01 family) 0.0172 0.0108 0.0292
Toxoplasma gondii PAN domain-containing protein 0.0027 0.0001 0.0002
Brugia malayi hypothetical protein 0.0119 0.0069 0.0187
Trichomonas vaginalis Clan CA, family C1, papain-like cysteine peptidase 0.3167 0.2334 1
Entamoeba histolytica cysteine protease, putative 0.0699 0.05 0.2141
Mycobacterium ulcerans hydrolase 0.0653 0.0466 1
Trichomonas vaginalis GTP-binding protein (q) alpha-11 subunit, gna11, putative 0.0035 0.0007 0.0029
Toxoplasma gondii kringle domain-containing protein 0.0164 0.0103 0.0439
Echinococcus granulosus Pyruvate dehydrogenase lipoamide kinase 0.0271 0.0182 0.0492
Loa Loa (eye worm) fli-1 protein 0.0104 0.0058 0.0157
Trypanosoma cruzi cysteine peptidase, putative 0.3712 0.274 0.7391
Onchocerca volvulus 0.0164 0.0103 0.0437
Trichomonas vaginalis fructose-bisphosphate aldolase, putative 0.0208 0.0135 0.0577
Brugia malayi PAN domain containing protein 0.0027 0.0001 0.0002
Loa Loa (eye worm) hypothetical protein 0.0027 0.0001 0.0002
Echinococcus multilocularis integrin beta 2 0.0118 0.0068 0.0185
Loa Loa (eye worm) hypothetical protein 0.0027 0.0001 0.0002
Loa Loa (eye worm) papain family cysteine protease containing protein 0.0699 0.05 0.1348
Schistosoma mansoni DNA polymerase eta 0.0038 0.0008 0.0023
Echinococcus multilocularis fat cadherin tumor suppressor 0.0053 0.002 0.0053
Loa Loa (eye worm) pip kinase 2 0.0094 0.005 0.0135
Schistosoma mansoni notch 0.0053 0.002 0.0053
Onchocerca volvulus 0.076 0.0545 0.2334
Schistosoma mansoni hypothetical protein 0.0698 0.0499 0.1347
Echinococcus multilocularis rhodopsin orphan GPCR 0.0049 0.0017 0.0046
Trichomonas vaginalis Clan CA, family C1, cathepsin B-like cysteine peptidase 0.0819 0.0589 0.2524
Echinococcus granulosus cathepsin b 0.5012 0.3706 1
Trypanosoma brucei developmentally regulated phosphoprotein 0.0271 0.0182 0.0665
Trypanosoma cruzi pyruvate dehydrogenase (lipoamide) kinase, putative 0.0095 0.0051 0.0138
Schistosoma mansoni amine GPCR 0.0049 0.0017 0.0046
Mycobacterium ulcerans ATP-dependent Clp protease proteolytic subunit 0.0122 0.0071 0.1294
Entamoeba histolytica cysteine proteinase, putative 0.1705 0.1248 0.5344
Echinococcus multilocularis suppression of tumorigenicity 18 protein 0.0043 0.0013 0.0034
Onchocerca volvulus 0.0167 0.0105 0.0446
Onchocerca volvulus 0.0049 0.0017 0.0071
Echinococcus granulosus cathepsin L 0.1705 0.1248 0.3366
Loa Loa (eye worm) hypothetical protein 0.0027 0.0001 0.0002
Brugia malayi GTP-binding regulatory protein alpha chain - starfish, putative 0.0035 0.0007 0.0018
Brugia malayi cathepsin L-like precursor 0.2161 0.1587 0.4281
Brugia malayi Domain found in Dishevelled, Egl-10, and Pleckstrin family protein 0.0034 0.0005 0.0015
Brugia malayi hypothetical protein 0.0049 0.0017 0.0046
Brugia malayi Trypsin family protein 0.0172 0.0108 0.0292
Schistosoma mansoni intermediate filament proteins 0.0038 0.0009 0.0024
Echinococcus multilocularis alpha 1A adrenergic receptor 0.0049 0.0017 0.0046
Entamoeba histolytica cysteine protease, putative 0.0699 0.05 0.2141
Brugia malayi Hemopexin family protein 0.076 0.0545 0.1471
Brugia malayi PAN domain containing protein 0.0027 0.0001 0.0002
Echinococcus multilocularis neurogenic locus notch protein 0.0053 0.002 0.0053
Loa Loa (eye worm) MH2 domain-containing protein 0.0183 0.0117 0.0315
Schistosoma mansoni slit 0.0053 0.002 0.0053
Entamoeba histolytica exodeoxyribonuclease III, putative 0.0043 0.0012 0.0053
Loa Loa (eye worm) PAN domain-containing protein 0.0027 0.0001 0.0002
Echinococcus multilocularis glutathione s transferase mu 0.0064 0.0028 0.0075
Leishmania major cathepsin L-like protease 0.3167 0.2334 0.8522
Brugia malayi guanine nucleotide-binding protein alpha-7 subunit, putative 0.0035 0.0007 0.0018
Onchocerca volvulus 0.0172 0.0108 0.0461
Trichomonas vaginalis CAMK family protein kinase 0.0026 0 0.0001
Loa Loa (eye worm) hypothetical protein 0.0049 0.0017 0.0046
Brugia malayi Domain found in Dishevelled, Egl-10, and Pleckstrin family protein 0.0034 0.0005 0.0015
Echinococcus multilocularis Tolloid protein 1 0.0051 0.0018 0.0049
Entamoeba histolytica cysteine protease, putative 0.1705 0.1248 0.5344
Echinococcus multilocularis COUP TF:Svp nuclear hormone receptor 0.003 0.0003 0.0007
Brugia malayi Smad1 0.0183 0.0117 0.0315
Echinococcus multilocularis NADP dependent isocitrate dehydrogenase 0.0169 0.0106 0.0287
Echinococcus multilocularis laminin 0.0051 0.0018 0.0049
Brugia malayi cathepsin L precursor 0.0699 0.05 0.1348
Onchocerca volvulus Neurogenic locus notch protein homolog 0.0053 0.002 0.0082
Mycobacterium ulcerans hypothetical protein 0.0172 0.0108 0.2112
Giardia lamblia Hypothetical protein 0.0699 0.05 0.3345
Schistosoma mansoni lamin 0.0038 0.0009 0.0024
Echinococcus granulosus orexin receptor type 2 0.0049 0.0017 0.0046
Loa Loa (eye worm) matrix metalloproteinase 0.0536 0.0379 0.1022
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.1705 0.1248 0.5344
Brugia malayi hypothetical protein 0.0532 0.0376 0.1015
Plasmodium falciparum dipeptidyl aminopeptidase 3 0.078 0.0561 0.2397
Loa Loa (eye worm) hypothetical protein 0.0053 0.002 0.0053
Schistosoma mansoni peptide (FMRFamide/somatostatin)-like receptor 0.0049 0.0017 0.0046
Schistosoma mansoni GTP-binding protein (I) alpha-2 subunit gnai2 0.0035 0.0007 0.0018
Echinococcus multilocularis serotonin receptor 0.0049 0.0017 0.0046
Brugia malayi Papain family cysteine protease containing protein 0.1705 0.1248 0.3366
Schistosoma mansoni mixed-lineage leukemia protein mll 0.0095 0.0051 0.0138
Echinococcus multilocularis 7TM GPCR, rhodopsin 0.0049 0.0017 0.0046
Schistosoma mansoni Smad4 0.0082 0.0041 0.0112
Treponema pallidum ATP-dependent Clp protease proteolytic subunit 0.0122 0.0071 0.4816
Echinococcus granulosus subfamily S1A unassigned peptidase S01 family 0.0172 0.0108 0.0292
Onchocerca volvulus 0.0035 0.0007 0.0026
Schistosoma mansoni jumonji domain containing protein 0.0043 0.0012 0.0033
Loa Loa (eye worm) hypothetical protein 0.0049 0.0017 0.0046
Trypanosoma cruzi cruzipain precursor, putative 0.3712 0.274 0.7391
Brugia malayi EGF-like domain containing protein 0.0053 0.002 0.0053
Brugia malayi hypothetical protein 0.0049 0.0017 0.0046
Brugia malayi Steroid receptor seven-up type 2 0.003 0.0003 0.0007
Giardia lamblia Cathepsin B precursor 0.0819 0.0589 0.3946
Brugia malayi hypothetical protein 0.0049 0.0017 0.0046
Trypanosoma cruzi cysteine peptidase C (CPC), putative 0.5012 0.3706 1
Onchocerca volvulus Arrow homolog 0.0051 0.0018 0.0075
Onchocerca volvulus 0.0034 0.0005 0.0021
Brugia malayi Calcium binding EGF domain containing protein 0.0051 0.0018 0.0049
Brugia malayi cathepsin Z-like cysteine proteinase 0.0819 0.0589 0.159
Echinococcus multilocularis peptide (allatostatin:somatostatin) 0.0049 0.0017 0.0046
Onchocerca volvulus Cathepsin L homolog 0.0699 0.05 0.2139
Plasmodium falciparum ATP-dependent Clp protease proteolytic subunit 0.0122 0.0071 0.0298
Echinococcus multilocularis lamin 0.0038 0.0009 0.0024
Trypanosoma brucei pyruvate dehydrogenase (lipoamide) kinase, putative 0.0095 0.0051 0.0186
Brugia malayi mothers against decapentaplegic homolog 3 0.0082 0.0041 0.0112
Loa Loa (eye worm) hypothetical protein 0.0053 0.002 0.0053
Onchocerca volvulus Neurogenic locus notch homolog 0.0053 0.002 0.0082
Onchocerca volvulus 0.0305 0.0207 0.0886
Schistosoma mansoni steroid hormone receptor ad4bp 0.003 0.0003 0.0007
Echinococcus granulosus Nuclear hormone receptor family member nhr 41 0.003 0.0003 0.0007
Schistosoma mansoni nuclear hormone receptor 0.003 0.0003 0.0007
Plasmodium falciparum serine repeat antigen 4 0.0699 0.05 0.2136
Echinococcus granulosus polycomb protein SCMH1 0.0038 0.0009 0.0023
Plasmodium falciparum glutathione reductase 0.0036 0.0007 0.0025
Brugia malayi Papain family cysteine protease containing protein 0.0699 0.05 0.1348
Trypanosoma cruzi cysteine proteinase, putative 0.1705 0.1248 0.3366
Onchocerca volvulus 0.0068 0.0031 0.0132
Entamoeba histolytica cysteine proteinase, putative 0.1705 0.1248 0.5344
Echinococcus multilocularis cathepsin l cysteine peptidase 0.3167 0.2334 0.6299
Trichomonas vaginalis Clan CA, family C1, cathepsin B-like cysteine peptidase 0.0819 0.0589 0.2524
Echinococcus granulosus Pleckstrin G protein interacting region 0.0034 0.0005 0.0015
Brugia malayi Serotonin receptor 0.0049 0.0017 0.0046
Loa Loa (eye worm) MH2 domain-containing protein 0.0082 0.0041 0.0112
Plasmodium vivax serine-repeat antigen (SERA), putative 0.0699 0.05 0.2126
Schistosoma mansoni biogenic amine (octopamine/dopamine) receptor 0.0049 0.0017 0.0046
Giardia lamblia Cathepsin B precursor 0.2033 0.1492 1
Onchocerca volvulus 0.2161 0.1587 0.6796
Loa Loa (eye worm) hypothetical protein 0.0082 0.0041 0.0112
Schistosoma mansoni pyruvate dehydrogenase 0.0256 0.0171 0.0461
Loa Loa (eye worm) GTP-binding regulatory protein Gs alpha-S chain 0.082 0.059 0.1593
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.3712 0.274 1
Leishmania major cathepsin L-like protease 0.3167 0.2334 0.8522
Echinococcus multilocularis Smad4 0.0183 0.0117 0.0315
Echinococcus granulosus delta-like protein 1 0.0053 0.002 0.0053
Schistosoma mansoni cpg binding protein 0.0049 0.0017 0.0045
Brugia malayi MH2 domain containing protein 0.2687 0.1978 0.5336
Schistosoma mansoni subfamily M12A unassigned peptidase (M12 family) 0.0051 0.0018 0.0049
Loa Loa (eye worm) integrin beta-2 0.016 0.0099 0.0268
Schistosoma mansoni cpg binding protein 0.0045 0.0014 0.0037
Brugia malayi notch-like transmembrane receptor 0.0053 0.002 0.0053
Loa Loa (eye worm) hypothetical protein 0.0338 0.0232 0.0626
Brugia malayi Serotonin receptor 0.0049 0.0017 0.0046
Schistosoma mansoni cathepsin B-like peptidase (C01 family) 0.0699 0.05 0.1348
Entamoeba histolytica hypothetical protein 0.0056 0.0022 0.0093
Brugia malayi Matrix metalloprotease, N-terminal domain containing protein 0.0653 0.0466 0.1256
Echinococcus multilocularis survival motor neuron protein 1 0.0169 0.0106 0.0287
Plasmodium vivax serine-repeat antigen 3 (SERA) 0.0699 0.05 0.2126
Giardia lamblia Cathepsin B precursor 0.0699 0.05 0.3345
Trichomonas vaginalis Clan CA, family C1, papain-like cysteine peptidase 0.3167 0.2334 1
Echinococcus multilocularis GPCR, family 2 0.0698 0.0499 0.1347
Brugia malayi glutathione reductase 0.0036 0.0007 0.0019
Plasmodium vivax serine-repeat antigen 4 (SERA), putative 0.0699 0.05 0.2126
Loa Loa (eye worm) hypothetical protein 0.0053 0.002 0.0053
Mycobacterium tuberculosis Probable reductase 0.0081 0.0041 0.0742
Echinococcus granulosus rhodopsin orphan GPCR 0.0049 0.0017 0.0046
Onchocerca volvulus Papilin homolog 0.0039 0.001 0.004
Trichomonas vaginalis Clan CA, family C1, papain-like cysteine peptidase 0.3167 0.2334 1
Loa Loa (eye worm) hypothetical protein 0.0049 0.0017 0.0046
Onchocerca volvulus 0.3167 0.2334 1
Trichomonas vaginalis Clan CA, family C1, papain-like cysteine peptidase 0.3167 0.2334 1
Mycobacterium leprae DIHYDROLIPOAMIDE DEHYDROGENASE LPD (LIPOAMIDE REDUCTASE (NADH)) (LIPOYL DEHYDROGENASE) (DIHYDROLIPOYL DEHYDROGENASE) (DIAPHORASE 0.0091 0.0048 0.0797
Brugia malayi Cathepsin L-like precursor 0.3167 0.2334 0.6299
Echinococcus granulosus Blood coagulation inhibitor Disintegrin 0.0095 0.0051 0.0137
Brugia malayi G-protein coupled receptor 0.0049 0.0017 0.0046
Schistosoma mansoni opsin-like receptor 0.0049 0.0017 0.0046
Echinococcus multilocularis fibropellin Ia 0.0053 0.002 0.0053
Echinococcus granulosus expressed protein 0.0035 0.0007 0.0018
Loa Loa (eye worm) hypothetical protein 0.0053 0.002 0.0053
Echinococcus multilocularis Glutamate receptor, ionotropic kainate 2 0.003 0.0002 0.0007
Brugia malayi Muscle positioning protein 4 0.0053 0.002 0.0053
Echinococcus multilocularis glutamate receptor NMDA 0.0045 0.0014 0.0038
Trypanosoma brucei importin beta-1 subunit, putative 0.0068 0.0031 0.0115
Echinococcus granulosus aldehyde dehydrogenase mitochondrial 0.0093 0.005 0.0134
Brugia malayi Metabotropic glutamate receptor precursor. 0.0028 0.0001 0.0003
Schistosoma mansoni biogenic amine (dopamine) receptor 0.0049 0.0017 0.0046
Echinococcus granulosus G protein coupled 5 hydroxytryptamine receptor 0.0049 0.0017 0.0046
Schistosoma mansoni matrix metallopeptidase-7 (M10 family) 0.0536 0.0379 0.1022
Brugia malayi Tachykinin-like peptides receptor 99D 0.0188 0.012 0.0325
Loa Loa (eye worm) hypothetical protein 0.0049 0.0017 0.0046
Plasmodium vivax serine-repeat antigen 5 (SERA) 0.0699 0.05 0.2126
Brugia malayi Guanine nucleotide-binding protein alpha-6 subunit, putative 0.0035 0.0007 0.0018
Giardia lamblia Cathepsin L-like protease 0.0699 0.05 0.3345
Plasmodium vivax serine-repeat antigen (SERA) 0.0699 0.05 0.2126
Loa Loa (eye worm) hypothetical protein 0.0051 0.0018 0.0049
Mycobacterium leprae PROBABLE NADH DEHYDROGENASE NDH 0.0081 0.0041 0.0648
Loa Loa (eye worm) hypothetical protein 0.0027 0.0001 0.0002
Echinococcus granulosus transmembrane protease serine 3 0.0172 0.0108 0.0292
Loa Loa (eye worm) trypsin family protein 0.0172 0.0108 0.0292
Entamoeba histolytica acetyltransferase, GNAT family 0.0028 0.0001 0.0006
Trichomonas vaginalis fructose-bisphosphate aldolase, putative 0.0208 0.0135 0.0577
Echinococcus granulosus rhodopsin orphan GPCR 0.0049 0.0017 0.0046
Onchocerca volvulus 0.0053 0.002 0.0082
Echinococcus multilocularis rhodopsin orphan GPCR 0.0049 0.0017 0.0046
Brugia malayi Cadherin domain containing protein 0.0053 0.002 0.0053
Entamoeba histolytica cysteine protease, putative 0.1705 0.1248 0.5344
Loa Loa (eye worm) intermediate filament tail domain-containing protein 0.0038 0.0009 0.0024
Echinococcus granulosus subfamily M12B unassigned peptidase 0.0032 0.0004 0.0012
Echinococcus multilocularis neurogenic locus protein delta 0.0053 0.002 0.0053
Brugia malayi Nuclear hormone receptor family member nhr-1 0.003 0.0003 0.0007
Brugia malayi isocitrate dehydrogenase 0.0169 0.0106 0.0287
Loa Loa (eye worm) nuclear hormone receptor family member nhr-31 0.003 0.0003 0.0007
Echinococcus multilocularis ATP dependent Clp protease proteolytic subunit 0.0122 0.0071 0.0191
Schistosoma mansoni ap endonuclease 0.0043 0.0012 0.0033
Schistosoma mansoni notch 0.0053 0.002 0.0053
Brugia malayi EGF-like domain containing protein 0.0053 0.002 0.0053
Brugia malayi PAN domain containing protein 0.0027 0.0001 0.0002
Loa Loa (eye worm) latrophilin receptor protein 2 0.0698 0.0499 0.1347
Echinococcus multilocularis neuropeptides capa receptor 0.0049 0.0017 0.0046
Plasmodium falciparum serine repeat antigen 3 0.0699 0.05 0.2136
Trypanosoma brucei cysteine peptidase C (CPC) 0.2033 0.1492 0.5444
Trichomonas vaginalis fructose-bisphosphate aldolase, putative 0.0208 0.0135 0.0577
Loa Loa (eye worm) ctsf protein 0.3167 0.2334 0.6299
Toxoplasma gondii PAN/Apple domain-containing protein 0.0027 0.0001 0.0002
Loa Loa (eye worm) hypothetical protein 0.2205 0.1619 0.4369
Echinococcus multilocularis adam 17 protease 0.0151 0.0092 0.0249
Brugia malayi Cathepsin L-like precursor 0.3167 0.2334 0.6299
Echinococcus multilocularis geminin 0.0559 0.0396 0.1069
Brugia malayi calcium-independent alpha-latrotoxin receptor 2, putative 0.0698 0.0499 0.1347
Onchocerca volvulus 0.0038 0.0009 0.0036
Loa Loa (eye worm) hypothetical protein 0.0053 0.002 0.0053
Echinococcus granulosus thioredoxin glutathione reductase 0.0036 0.0007 0.0019
Loa Loa (eye worm) hypothetical protein 0.0271 0.0182 0.0492
Brugia malayi G protein-coupled receptor F59B2.13 0.0049 0.0017 0.0046
Schistosoma mansoni laminin gamma-3 chain 0.0053 0.002 0.0053
Schistosoma mansoni sex comb on midleg homolog 0.0038 0.0009 0.0023
Brugia malayi jmjC domain containing protein 0.0047 0.0015 0.0041
Schistosoma mansoni cercarial elastase (S01 family) 0.0172 0.0108 0.0292
Onchocerca volvulus Matrilysin homolog 0.0536 0.0379 0.1621
Leishmania major developmentally regulated phosphoprotein-like protein 0.0271 0.0182 0.0665
Schistosoma mansoni cathepsin s 0.1006 0.0728 0.1965
Plasmodium vivax serine-repeat antigen 4 (SERA) 0.0699 0.05 0.2126
Brugia malayi AKH receptor 0.0049 0.0017 0.0046
Echinococcus granulosus glutathione S transferase 0.0217 0.0142 0.0383
Loa Loa (eye worm) hypothetical protein 0.0038 0.0008 0.0023
Echinococcus granulosus cysteine protease 0.1705 0.1248 0.3366
Loa Loa (eye worm) Notch2 0.0053 0.002 0.0053
Schistosoma mansoni myosin xvIII 0.0049 0.0017 0.0046
Schistosoma mansoni NADP-specific isocitrate dehydrogenase 0.0169 0.0106 0.0287
Entamoeba histolytica cysteine protease, putative 0.1705 0.1248 0.5344
Loa Loa (eye worm) D-ets-4 DNA binding domain-containing protein 0.0034 0.0006 0.0016
Loa Loa (eye worm) hypothetical protein 0.0064 0.0028 0.0075
Loa Loa (eye worm) 5-hydroxytryptamine 2C receptor 0.0049 0.0017 0.0046
Echinococcus multilocularis metabotropic glutamate receptor 5 0.0033 0.0005 0.0013
Plasmodium falciparum cysteine proteinase falcipain 1 0.1705 0.1248 0.5341
Echinococcus granulosus guanine nucleotide binding protein subunit 0.0035 0.0007 0.0018
Giardia lamblia Cathepsin B precursor 0.2033 0.1492 1
Brugia malayi MH1 domain containing protein 0.0183 0.0117 0.0315
Echinococcus granulosus lysine specific demethylase 5A 0.0047 0.0015 0.0041
Brugia malayi metalloprotease disintegrin 16 with thrombospondin type I motif 0.0071 0.0033 0.009
Echinococcus multilocularis dna polymerase eta 0.0038 0.0008 0.0023
Schistosoma mansoni smad1 5 8 and 0.0183 0.0117 0.0315
Echinococcus granulosus Transcription factor JmjC domain containing protein 0.0043 0.0012 0.0033
Echinococcus granulosus neurogenic locus protein delta 0.0053 0.002 0.0053
Echinococcus granulosus cathepsin L cysteine protease 0.1705 0.1248 0.3366
Onchocerca volvulus 0.0094 0.005 0.0212
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.2161 0.1587 0.6797
Toxoplasma gondii isocitrate dehydrogenase 0.0169 0.0106 0.0456
Schistosoma mansoni cercarial elastase (S01 family) 0.0172 0.0108 0.0292
Brugia malayi Cathepsin L-like precursor 0.3167 0.2334 0.6299
Echinococcus multilocularis cysteine protease 0.3167 0.2334 0.6299
Schistosoma mansoni dishevelled 0.0034 0.0005 0.0015
Loa Loa (eye worm) hypothetical protein 0.0699 0.05 0.1348
Echinococcus multilocularis mothers against decapentaplegic 5 0.0183 0.0117 0.0315
Schistosoma mansoni sodium/chloride dependent transporter 0.0054 0.0021 0.0056
Brugia malayi Sodium:neurotransmitter symporter family protein 0.0054 0.0021 0.0056
Brugia malayi Matrixin family protein 0.1296 0.0944 0.2546
Echinococcus multilocularis a disintegrin and metalloproteinase with 0.0123 0.0072 0.0195
Echinococcus granulosus importin subunit beta 1 0.0068 0.0031 0.0085
Toxoplasma gondii ATP-dependent Clp endopeptidase, proteolytic subunit ClpP domain-containing protein 0.0122 0.0071 0.0304
Entamoeba histolytica cysteine protease, putative 0.1705 0.1248 0.5344
Brugia malayi PAN domain containing protein 0.0027 0.0001 0.0002
Schistosoma mansoni neuropeptide f receptor 76f 0.0049 0.0017 0.0046
Schistosoma mansoni transient receptor potential channel 0.0091 0.0048 0.0129
Brugia malayi Trypsin family protein 0.0172 0.0108 0.0292
Brugia malayi guanine nucleotide-binding protein alpha-3 subunit, putative 0.0035 0.0007 0.0018
Schistosoma mansoni cercarial elastase (S01 family) 0.0172 0.0108 0.0292
Echinococcus granulosus growth hormone secretagogue receptor type 1 0.0049 0.0017 0.0046
Trypanosoma cruzi cysteine protease, putative 0.1705 0.1248 0.3366
Trypanosoma cruzi cruzipain precursor, putative 0.1006 0.0728 0.1965
Brugia malayi PAN domain containing protein 0.0027 0.0001 0.0002
Trichomonas vaginalis glutaminyl-tRNA synthetase, putative 0.0049 0.0017 0.0073
Echinococcus granulosus integrin beta 2 0.0118 0.0068 0.0185
Loa Loa (eye worm) cysteine proteinase cathepsin Z 0.0819 0.0589 0.159
Brugia malayi ecdysteroid receptor 0.003 0.0003 0.0007
Echinococcus multilocularis neurogenic locus notch protein 0.0053 0.002 0.0053
Schistosoma mansoni notch 0.0053 0.002 0.0053
Loa Loa (eye worm) nuclear hormone receptor family member nhr-41 0.003 0.0003 0.0007
Leishmania major aldehyde dehydrogenase, mitochondrial precursor 0.0093 0.005 0.0181
Trypanosoma cruzi PAB1-binding protein , putative 0.0201 0.013 0.0351
Schistosoma mansoni opsin-like receptor 0.0049 0.0017 0.0046
Loa Loa (eye worm) acetyltransferase 0.0106 0.0059 0.0159
Giardia lamblia Cysteine protease 0.0699 0.05 0.3345
Onchocerca volvulus 0.0049 0.0017 0.0071
Onchocerca volvulus 0.0049 0.0017 0.0071
Mycobacterium tuberculosis Probable exodeoxyribonuclease III protein XthA (exonuclease III) (EXO III) (AP endonuclease VI) 0.0043 0.0012 0.0114
Brugia malayi DIX domain containing protein 0.0034 0.0005 0.0015
Schistosoma mansoni biogenic amine (dopamine) receptor 0.0049 0.0017 0.0046
Schistosoma mansoni biogenic amine (dopamine) receptor 0.0049 0.0017 0.0046
Schistosoma mansoni septate junction protein 0.0053 0.002 0.0053
Trypanosoma cruzi cysteine peptidase, clan CA, family C1, cathepsin L-like, putative 0.2706 0.1992 0.5374
Brugia malayi Trypsin family protein 0.0338 0.0232 0.0626
Echinococcus granulosus neurogenic locus notch protein 4 0.0053 0.002 0.0053
Schistosoma mansoni cathepsin B-like peptidase (C01 family) 0.5012 0.3706 1
Echinococcus granulosus protein jagged 2 0.0053 0.002 0.0053
Brugia malayi PAN domain containing protein 0.0027 0.0001 0.0002
Brugia malayi Transmembrane cell adhesion receptor mua-3 precursor, putative 0.0053 0.002 0.0053
Echinococcus multilocularis glutamate (NMDA) receptor subunit 0.0055 0.0021 0.0057
Brugia malayi glutathione transferase 0.0064 0.0028 0.0075
Echinococcus multilocularis Mastin 0.0244 0.0162 0.0436
Echinococcus granulosus neural cadherin 0.0053 0.002 0.0053
Schistosoma mansoni peptidase Clp (S14 family) 0.0122 0.0071 0.0191
Schistosoma mansoni cellular tumor antigen P53 0.0034 0.0006 0.0015
Loa Loa (eye worm) glutamate receptor 0.0028 0.0001 0.0003
Schistosoma mansoni hypothetical protein 0.0164 0.0103 0.0277
Echinococcus granulosus guanine nucleotide binding protein G protein 0.0035 0.0007 0.0018
Schistosoma mansoni ADAMTS5 peptidase (M12 family) 0.0123 0.0072 0.0195
Brugia malayi MH1 domain containing protein 0.0101 0.0056 0.015
Brugia malayi Cathepsin L-like precursor 0.1006 0.0728 0.1965
Schistosoma mansoni cpg binding protein 0.0049 0.0017 0.0045
Echinococcus multilocularis lamin dm0 0.0038 0.0009 0.0024
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.3712 0.274 1
Echinococcus multilocularis isocitrate dehydrogenase 0.0169 0.0106 0.0287
Brugia malayi Cytochrome P450 family protein 0.0027 0.0001 0.0002
Entamoeba histolytica cysteine proteinase, putative 0.1705 0.1248 0.5344
Giardia lamblia Dipeptidyl-peptidase I precursor 0.078 0.0561 0.3753
Loa Loa (eye worm) hypothetical protein 0.0681 0.0487 0.1314
Echinococcus multilocularis short transient receptor potential channel 6 0.0091 0.0048 0.0129
Echinococcus multilocularis notch 0.0053 0.002 0.0053
Trichomonas vaginalis CAMK family protein kinase 0.0053 0.002 0.0086
Brugia malayi hypothetical protein 0.0049 0.0017 0.0046
Entamoeba histolytica G protein alpha subunit, putative 0.0035 0.0007 0.0029
Schistosoma mansoni glutamate receptor NMDA 0.0055 0.0021 0.0057
Toxoplasma gondii isocitrate dehydrogenase 0.0169 0.0106 0.0456
Loa Loa (eye worm) MH1 domain-containing protein 0.0183 0.0117 0.0315
Echinococcus multilocularis cathepsin L 0.0699 0.05 0.1348
Echinococcus multilocularis transient receptor potential ion channel A 0.0132 0.0079 0.0213
Loa Loa (eye worm) nuclear hormone receptor family member nhr-40 0.003 0.0003 0.0007
Schistosoma mansoni transient receptor potential channel 0.0137 0.0082 0.0222
Plasmodium falciparum serine repeat antigen 8 0.0699 0.05 0.2136
Loa Loa (eye worm) PLK/PLK1 protein kinase 0.0053 0.002 0.0054
Echinococcus multilocularis Ataxin 2, N terminal,domain containing protein 0.009 0.0048 0.0129
Schistosoma mansoni subfamily S1A unassigned peptidase (S01 family) 0.0172 0.0108 0.0292
Echinococcus multilocularis smad 0.0183 0.0117 0.0315
Loa Loa (eye worm) PAN domain-containing protein 0.0027 0.0001 0.0002
Plasmodium falciparum ataxin-2 like protein, putative 0.0201 0.013 0.0552
Schistosoma mansoni dep domain containing protein 0.0034 0.0005 0.0015
Schistosoma mansoni hypothetical protein 0.0055 0.0022 0.0058
Loa Loa (eye worm) Smad1 0.0183 0.0117 0.0315
Loa Loa (eye worm) hypothetical protein 0.0053 0.002 0.0053
Echinococcus granulosus tumor protein p63 0.0231 0.0152 0.0411
Echinococcus granulosus GPCR family 2 0.0698 0.0499 0.1347
Echinococcus multilocularis rhodopsin orphan GPCR 0.0049 0.0017 0.0046
Loa Loa (eye worm) hypothetical protein 0.0032 0.0004 0.0012
Onchocerca volvulus Slit protein homolog 0.006 0.0025 0.0105
Brugia malayi Matrixin family protein 0.0536 0.0379 0.1022
Onchocerca volvulus 0.3167 0.2334 1
Mycobacterium tuberculosis Possible penicillin-binding protein 0.0163 0.0102 0.2069
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.3167 0.2334 1
Loa Loa (eye worm) isocitrate dehydrogenase 0.0169 0.0106 0.0287
Echinococcus multilocularis importin subunit beta 1 0.0068 0.0031 0.0085
Schistosoma mansoni scm-relatedprotein containing 4 mbt domains (sfmbt) 0.0038 0.0009 0.0023
Brugia malayi Nuclear hormone receptor family member nhr-31 0.003 0.0003 0.0007
Loa Loa (eye worm) GTP-binding regulatory protein alpha chain 0.0035 0.0007 0.0018
Trypanosoma cruzi cysteine peptidase (N-terminal), putative 0.1705 0.1248 0.3366
Schistosoma mansoni GST class-mu 0.0064 0.0028 0.0075
Schistosoma mansoni lamin 0.0038 0.0009 0.0024
Toxoplasma gondii cathepsin CPC2 0.078 0.0561 0.2402
Echinococcus granulosus glutamate NMDA receptor subunit 0.0055 0.0021 0.0057
Echinococcus multilocularis FTZ F1 nuclear receptor protein 0.003 0.0003 0.0007
Brugia malayi hypothetical protein 0.0049 0.0017 0.0046
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.3712 0.274 1
Echinococcus multilocularis bromodomain adjacent to zinc finger domain 0.0049 0.0017 0.0047
Mycobacterium ulcerans glutaminase 0.0151 0.0093 0.1776
Loa Loa (eye worm) hypothetical protein 0.0699 0.05 0.1348
Entamoeba histolytica cysteine proteinase, putative 0.3167 0.2334 1
Onchocerca volvulus 0.0049 0.0017 0.0071
Echinococcus granulosus Tolloid protein 1 0.0051 0.0018 0.0049
Schistosoma mansoni Smad4 0.0183 0.0117 0.0315
Schistosoma mansoni phosphatidylinositol-4-phosphate 5-kinase type II 0.0094 0.005 0.0135
Schistosoma mansoni retinoid-x-receptor (RXR) 0.003 0.0003 0.0007
Onchocerca volvulus 0.3167 0.2334 1
Brugia malayi hypothetical protein 0.0049 0.0017 0.0046
Schistosoma mansoni Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) 0.082 0.059 0.1593
Schistosoma mansoni SmCL2-like peptidase (C01 family) 0.1705 0.1248 0.3366
Onchocerca volvulus Segment polarity protein dishevelled homolog 0.0034 0.0005 0.0021
Toxoplasma gondii PAN domain-containing protein 0.0027 0.0001 0.0002
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.3167 0.2334 1
Echinococcus granulosus gtp binding protein I alpha 1subunit 0.0035 0.0007 0.0018
Echinococcus granulosus glutathione s transferase mu 0.0064 0.0028 0.0075
Mycobacterium tuberculosis Probable isocitrate dehydrogenase [NADP] Icd1 (oxalosuccinate decarboxylase) (IDH) (NADP+-specific ICDH) (IDP) 0.0169 0.0106 0.2166
Echinococcus multilocularis Peptidase S1 S6, chymotrypsin Hap 0.0172 0.0108 0.0292
Echinococcus multilocularis glutathione S-transferase 0.0064 0.0028 0.0075
Schistosoma mansoni hypothetical protein 0.0119 0.0069 0.0187
Loa Loa (eye worm) hypothetical protein 0.0049 0.0017 0.0046
Loa Loa (eye worm) hypothetical protein 0.0053 0.002 0.0053
Loa Loa (eye worm) hypothetical protein 0.0053 0.002 0.0053
Onchocerca volvulus 0.0536 0.0379 0.1621
Brugia malayi hypothetical protein 0.0169 0.0106 0.0287
Plasmodium falciparum serine repeat antigen 7 0.0699 0.05 0.2136
Echinococcus multilocularis cathepsin b 0.5012 0.3706 1
Schistosoma mansoni cercarial elastase (S01 family) 0.0172 0.0108 0.0292
Onchocerca volvulus Cathepsin L homolog 0.3167 0.2334 1
Loa Loa (eye worm) hypothetical protein 0.0049 0.0017 0.0046
Echinococcus multilocularis thioredoxin glutathione reductase 0.0036 0.0007 0.0019
Echinococcus multilocularis guanine nucleotide binding protein (G protein) 0.0035 0.0007 0.0018
Giardia lamblia Cathepsin L precursor 0.0699 0.05 0.3345
Loa Loa (eye worm) hypothetical protein 0.0053 0.002 0.0053
Brugia malayi RNA recognition motif domain containing protein 0.0444 0.0311 0.0838
Trypanosoma cruzi cysteine peptidase C (CPC), putative 0.2033 0.1492 0.4024
Leishmania major importin beta-1 subunit, putative 0.0056 0.0022 0.008
Schistosoma mansoni GTP-binding protein (I) alpha-1subunit gnai1 0.0035 0.0007 0.0018
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.3712 0.274 1
Brugia malayi ImpB/MucB/SamB family protein 0.0038 0.0008 0.0023
Echinococcus granulosus g protein coupled receptor 0.0049 0.0017 0.0046
Trichomonas vaginalis CAMK family protein kinase 0.0053 0.002 0.0086
Echinococcus multilocularis sodium and chloride dependent glycine 0.0054 0.0021 0.0056
Loa Loa (eye worm) hypothetical protein 0.0172 0.0108 0.0292
Plasmodium vivax serine-repeat antigen (SERA), putative 0.0699 0.05 0.2126
Entamoeba histolytica fructose-1,6-bisphosphate aldolase, putative 0.0208 0.0135 0.0577
Onchocerca volvulus Cathepsin F homolog 0.3167 0.2334 1
Loa Loa (eye worm) hypothetical protein 0.0049 0.0017 0.0046
Schistosoma mansoni subfamily S1A unassigned peptidase (S01 family) 0.0172 0.0108 0.0292
Brugia malayi Nuclear hormone receptor-like 1 0.003 0.0003 0.0007
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.3712 0.274 1
Echinococcus multilocularis cathepsin l cysteine peptidase 0.3167 0.2334 0.6299
Echinococcus multilocularis guanine nucleotide binding protein subunit 0.0035 0.0007 0.0018
Schistosoma mansoni Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) 0.082 0.059 0.1593
Plasmodium vivax vivapain-2 0.3167 0.2334 1
Brugia malayi intermediate filament protein 0.0038 0.0009 0.0024
Loa Loa (eye worm) hypothetical protein 0.0049 0.0017 0.0046
Brugia malayi Calcium binding EGF domain containing protein 0.0053 0.002 0.0053
Brugia malayi guanine nucleotide-binding protein G(o), alpha subunit, putative 0.0035 0.0007 0.0018
Loa Loa (eye worm) hypothetical protein 0.0053 0.002 0.0053
Brugia malayi Importin beta-1 subunit 0.0068 0.0031 0.0085
Loa Loa (eye worm) hypothetical protein 0.0201 0.013 0.0351
Mycobacterium tuberculosis Probable nitrite reductase [NAD(P)H] large subunit [FAD flavoprotein] NirB 0.0081 0.0041 0.0742
Loa Loa (eye worm) hypothetical protein 0.0049 0.0017 0.0046
Schistosoma mansoni subfamily S1A unassigned peptidase (S01 family) 0.0338 0.0232 0.0626
Trichomonas vaginalis Clan CA, family C1, papain-like cysteine peptidase 0.3167 0.2334 1
Echinococcus granulosus protein jagged 1 0.0053 0.002 0.0053
Trypanosoma cruzi apurinic/apyrimidinic endonuclease 0.0043 0.0012 0.0033
Echinococcus multilocularis biogenic amine (5HT) receptor 0.0049 0.0017 0.0046
Echinococcus granulosus g protein linked acetylcholine receptor gar 2a 0.0049 0.0017 0.0046
Trichomonas vaginalis Clan CA, family C1, cathepsin B-like cysteine peptidase 0.0819 0.0589 0.2524
Schistosoma mansoni transient receptor potential channel 0.0091 0.0048 0.0129
Onchocerca volvulus Protein ultraspiracle homolog 0.003 0.0003 0.0009
Trichomonas vaginalis Importin beta-1 subunit, putative 0.0056 0.0022 0.0093
Loa Loa (eye worm) nuclear Hormone Receptor family member 0.003 0.0003 0.0007
Brugia malayi cathepsin L-like cysteine proteinase, identical 0.1006 0.0728 0.1965
Loa Loa (eye worm) G-protein coupled receptor 0.0049 0.0017 0.0046
Plasmodium vivax vivapain-1 0.1705 0.1248 0.5335
Loa Loa (eye worm) hypothetical protein 0.0049 0.0017 0.0046
Brugia malayi Ets-domain containing protein 0.0034 0.0006 0.0016
Loa Loa (eye worm) hypothetical protein 0.0038 0.0009 0.0023
Schistosoma mansoni smad 0.0183 0.0117 0.0315
Loa Loa (eye worm) hypothetical protein 0.0049 0.0017 0.0046
Loa Loa (eye worm) hypothetical protein 0.0051 0.0018 0.0049
Schistosoma mansoni nuclear hormone receptor nor-1/nor-2 0.003 0.0003 0.0007
Schistosoma mansoni GTP-binding protein alpha subunit gna 0.0035 0.0007 0.0018
Brugia malayi Nuclear hormone receptor family member nhr-14 0.003 0.0003 0.0007
Toxoplasma gondii 1,3-beta-glucan synthase component protein 0.0222 0.0145 0.0622
Trypanosoma cruzi isocitrate dehydrogenase, putative 0.0169 0.0106 0.0287
Echinococcus granulosus NADP dependent isocitrate dehydrogenase 0.0169 0.0106 0.0287
Loa Loa (eye worm) hypothetical protein 0.0049 0.0017 0.0046
Onchocerca volvulus Putative cubilin 0.0053 0.002 0.0082
Brugia malayi PAN domain containing protein 0.0027 0.0001 0.0002
Loa Loa (eye worm) TAR-binding protein 0.0444 0.0311 0.0838
Echinococcus granulosus Glutamate receptor ionotropic kainate 2 0.003 0.0002 0.0007
Brugia malayi Probable ClpP-like protease 0.0122 0.0071 0.0191
Loa Loa (eye worm) nuclear hormone receptor family member nhr-14 0.003 0.0003 0.0007
Echinococcus multilocularis rhodopsin orphan GPCR 0.0049 0.0017 0.0046
Echinococcus multilocularis neuropeptide receptor 0.0049 0.0017 0.0046
Echinococcus multilocularis Basic leucine zipper (bZIP) transcription 0.0119 0.0069 0.0187
Onchocerca volvulus Dopamine\/Ecdysteroid receptor homolog 0.0049 0.0017 0.0071
Brugia malayi acetyltransferase, GNAT family protein 0.0106 0.0059 0.0159
Loa Loa (eye worm) hypothetical protein 0.003 0.0003 0.0007
Trypanosoma brucei DNA polymerase eta, putative 0.0038 0.0008 0.0031
Brugia malayi Nuclear hormone receptor family member nhr-25 0.003 0.0003 0.0007
Schistosoma mansoni TGF-beta signal transducer Smad2 0.0183 0.0117 0.0315
Echinococcus granulosus g-protein coupled receptor 0.0049 0.0017 0.0046
Entamoeba histolytica cysteine protease, putative 0.0699 0.05 0.2141
Schistosoma mansoni glutaminase 0.0151 0.0093 0.025
Echinococcus multilocularis glutathione S transferase 0.0049 0.0017 0.0046
Brugia malayi aminoadipate-semialdehyde dehydrogenase-phosphopantetheinyl transferase 0.0062 0.0026 0.0071
Schistosoma mansoni cathepsin B-like peptidase (C01 family) 0.2033 0.1492 0.4024
Echinococcus granulosus nmda type glutamate receptor 0.0054 0.002 0.0055
Entamoeba histolytica cysteine protease, putative 0.1705 0.1248 0.5344
Onchocerca volvulus Polycomb protein Sfmbt homolog 0.0038 0.0009 0.0035
Echinococcus multilocularis glutathione S transferase 0.0049 0.0017 0.0046
Schistosoma mansoni cathepsin B-like peptidase (C01 family) 0.0699 0.05 0.1348
Toxoplasma gondii microneme protein MIC17B 0.0027 0.0001 0.0002
Brugia malayi EGF-like domain containing protein 0.0053 0.002 0.0053
Onchocerca volvulus 0.0035 0.0007 0.0026
Schistosoma mansoni egf-like domain protein 0.0051 0.0018 0.0049
Echinococcus multilocularis thyrotropin releasing hormone receptor 0.0049 0.0017 0.0046
Schistosoma mansoni cell polarity protein 0.0053 0.002 0.0053
Toxoplasma gondii LsmAD domain-containing protein 0.0201 0.013 0.0558
Schistosoma mansoni matrix metallopeptidase-9 (M10 family) 0.0629 0.0448 0.121
Schistosoma mansoni serine/threonine protein kinase 0.0053 0.002 0.0054
Echinococcus granulosus guanine nucleotide binding protein G protein 0.0035 0.0007 0.0018
Schistosoma mansoni growth hormone secretagogue receptor 0.0049 0.0017 0.0046
Entamoeba histolytica cysteine protease, putative 0.1705 0.1248 0.5344
Echinococcus granulosus peptidase Clp S14 family 0.008 0.004 0.0107
Echinococcus multilocularis SAM and MBT domain containing protein 0.0038 0.0009 0.0023
Echinococcus multilocularis histone acetyltransferase MYST2 0.0043 0.0013 0.0034
Brugia malayi Ligand-binding domain of nuclear hormone receptor family protein 0.003 0.0003 0.0007
Mycobacterium leprae PROBABLE ATP-DEPENDENT CLP PROTEASE PROTEOLYTIC SUBUNIT 2 CLPP2 (ENDOPEPTIDASE CLP 2) 0.0122 0.0071 0.1306
Brugia malayi MH1 domain containing protein 0.0183 0.0117 0.0315
Echinococcus granulosus neuropeptides capa receptor 0.0049 0.0017 0.0046
Brugia malayi Cathepsin L-like precursor 0.2161 0.1587 0.4281
Brugia malayi Cathepsin L-like precursor 0.3167 0.2334 0.6299
Echinococcus granulosus peptide allatostatin:somatostatin 0.0049 0.0017 0.0046
Echinococcus multilocularis g protein linked acetylcholine receptor gar 2a 0.0049 0.0017 0.0046
Plasmodium falciparum isocitrate dehydrogenase [NADP], mitochondrial 0.0169 0.0106 0.045
Schistosoma mansoni cercarial elastase (S01 family) 0.0172 0.0108 0.0292
Echinococcus multilocularis neurogenic locus notch protein 4 0.0053 0.002 0.0053
Onchocerca volvulus 0.0053 0.002 0.0082
Toxoplasma gondii microneme protein MIC17A 0.0027 0.0001 0.0002
Schistosoma mansoni hypothetical protein 0.0053 0.002 0.0053
Schistosoma mansoni aminopeptidase PILS (M01 family) 0.0172 0.0108 0.0292
Echinococcus granulosus cathepsin L cysteine proteinase 0.3167 0.2334 0.6299
Schistosoma mansoni transient receptor potential channel 4 0.0137 0.0082 0.0222
Loa Loa (eye worm) hypothetical protein 0.0086 0.0044 0.012
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.3167 0.2334 1
Schistosoma mansoni smad1 5 8 and 0.0183 0.0117 0.0315
Schistosoma mansoni GTP-binding protein alpha subunit gna 0.0035 0.0007 0.0018
Trichomonas vaginalis Clan CA, family C1, papain-like cysteine peptidase 0.3167 0.2334 1
Echinococcus multilocularis snurportin 1 0.0731 0.0524 0.1414
Loa Loa (eye worm) hypothetical protein 0.0653 0.0466 0.1256
Brugia malayi Ligand-binding domain of nuclear hormone receptor family protein 0.003 0.0003 0.0007
Toxoplasma gondii subtilisin SUB12 0.0027 0.0001 0.0002
Echinococcus granulosus enteropeptidase 0.0244 0.0162 0.0436
Giardia lamblia Hypothetical protein 0.0699 0.05 0.3345
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.2161 0.1587 0.6797
Schistosoma mansoni ADAM17 peptidase (M12 family) 0.0151 0.0092 0.0249
Schistosoma mansoni subfamily M12B unassigned peptidase (M12 family) 0.0032 0.0004 0.0012
Loa Loa (eye worm) hypothetical protein 0.0049 0.0017 0.0046
Schistosoma mansoni biogenic amine receptor 0.0049 0.0017 0.0046
Echinococcus multilocularis NADP dependent isocitrate dehydrogenase 0.0169 0.0106 0.0287
Brugia malayi Cathepsin L-like precursor 0.3167 0.2334 0.6299
Loa Loa (eye worm) PAN domain-containing protein 0.0027 0.0001 0.0002
Loa Loa (eye worm) hypothetical protein 0.003 0.0003 0.0007
Loa Loa (eye worm) hypothetical protein 0.0047 0.0015 0.0042
Brugia malayi hypothetical protein 0.0062 0.0027 0.0072
Schistosoma mansoni trimeric G-protein alpha o subunit 0.0035 0.0007 0.0018
Trichomonas vaginalis Clan CA, family C1, cathepsin L or K-like cysteine peptidase 0.3167 0.2334 1
Brugia malayi Serotonin/octopamine receptor family protein 7 0.0049 0.0017 0.0046
Schistosoma mansoni histamine-responsive GPCR (AAF21638) 0.0049 0.0017 0.0046
Toxoplasma gondii histone lysine methyltransferase SET1 0.0089 0.0047 0.02
Toxoplasma gondii exonuclease III APE 0.0043 0.0012 0.0053
Loa Loa (eye worm) hypothetical protein 0.003 0.0003 0.0007
Onchocerca volvulus 0.0049 0.0017 0.0071
Echinococcus multilocularis lysine specific demethylase 5A 0.0043 0.0012 0.0033
Echinococcus multilocularis mothers against decapentaplegic 6 0.0082 0.0041 0.0112
Giardia lamblia Cathepsin L precursor 0.0699 0.05 0.3345
Echinococcus granulosus fibropellin Ia 0.0053 0.002 0.0053
Echinococcus multilocularis isocitrate dehydrogenase 2 (NADP+) 0.0169 0.0106 0.0287
Schistosoma mansoni retinoic acid receptor RXR 0.003 0.0003 0.0007
Schistosoma mansoni subfamily C1A unassigned peptidase (C01 family) 0.0699 0.05 0.1348
Echinococcus granulosus TGF beta signal transducer SmadC 0.0183 0.0117 0.0315
Giardia lamblia Cathepsin B-like cysteine proteinase 3 precursor 0.0699 0.05 0.3345
Echinococcus granulosus tachykinin peptides receptor 99D 0.0049 0.0017 0.0046
Brugia malayi GCC2 and GCC3 family protein 0.0053 0.002 0.0053
Mycobacterium ulcerans aldehyde dehydrogenase 0.0093 0.005 0.0822
Echinococcus multilocularis Blood coagulation inhibitor, Disintegrin 0.0095 0.0051 0.0137
Loa Loa (eye worm) hypothetical protein 0.003 0.0003 0.0007
Echinococcus multilocularis subfamily M12B unassigned peptidase 0.0032 0.0004 0.0012
Onchocerca volvulus 0.0045 0.0014 0.0056
Loa Loa (eye worm) hypothetical protein 0.003 0.0003 0.0007
Toxoplasma gondii hypothetical protein 0.0034 0.0005 0.0023
Echinococcus granulosus nmda type glutamate receptor 0.0052 0.0019 0.0051
Echinococcus granulosus bromodomain adjacent to zinc finger domain 0.0049 0.0017 0.0047
Brugia malayi hypothetical protein 0.0035 0.0007 0.0018
Onchocerca volvulus 0.0053 0.002 0.0082
Loa Loa (eye worm) follicle stimulating hormone receptor 0.0115 0.0066 0.0178
Loa Loa (eye worm) hypothetical protein 0.0049 0.0017 0.0046
Trypanosoma brucei trypanothione reductase 0.0036 0.0007 0.0026
Schistosoma mansoni tar DNA-binding protein 0.0444 0.0311 0.0838
Loa Loa (eye worm) hypothetical protein 0.0053 0.002 0.0053
Echinococcus multilocularis orexin receptor type 2 0.0049 0.0017 0.0046
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0699 0.05 0.2141
Onchocerca volvulus 0.0172 0.0108 0.0461
Echinococcus granulosus L aminoadipate semialdehyde 0.0062 0.0026 0.0071
Onchocerca volvulus 0.003 0.0003 0.0009
Brugia malayi exodeoxyribonuclease III family protein 0.0043 0.0012 0.0033
Schistosoma mansoni dishevelled 0.0034 0.0005 0.0015
Brugia malayi jmjC domain containing protein 0.0043 0.0012 0.0033
Brugia malayi CXXC zinc finger family protein 0.0045 0.0014 0.0037
Plasmodium falciparum beta-hydroxyacyl-ACP dehydratase 0.0061 0.0026 0.0104
Schistosoma mansoni hypothetical protein 0.0559 0.0396 0.1069
Schistosoma mansoni thyroid hormone receptor 0.003 0.0003 0.0007
Leishmania major pyruvate dehydrogenase (lipoamide) kinase, putative 0.0095 0.0051 0.0186
Schistosoma mansoni cathepsin B-like peptidase (C01 family) 0.5012 0.3706 1
Echinococcus granulosus allatostatin A receptor 0.0049 0.0017 0.0046
Brugia malayi Fli-1 protein 0.0104 0.0058 0.0157
Echinococcus granulosus glutamate receptor NMDA 0.0045 0.0014 0.0038
Loa Loa (eye worm) hypothetical protein 0.006 0.0025 0.0068
Brugia malayi Matrixin family protein 0.0536 0.0379 0.1022
Schistosoma mansoni sex comb on midleg homolog 0.0038 0.0009 0.0023
Trichomonas vaginalis fructose-bisphosphate aldolase, putative 0.0208 0.0135 0.0577
Plasmodium vivax unspecified product 0.1705 0.1248 0.5335
Mycobacterium leprae PROBABLE HYDROLASE 0.0653 0.0466 1
Plasmodium vivax serine-repeat antigen (SERA) 0.0699 0.05 0.2126
Echinococcus multilocularis cpg binding protein 0.0049 0.0017 0.0045
Leishmania major cathepsin L-like protease 0.3712 0.274 1
Loa Loa (eye worm) hypothetical protein 0.0049 0.0017 0.0046
Onchocerca volvulus Steroid hormone receptor family member cnr14 homolog 0.003 0.0003 0.0009
Schistosoma mansoni biogenic amine (5HT) receptor 0.0049 0.0017 0.0046
Schistosoma mansoni GTP-binding protein (q) alpha-11 subunit gna11 0.0035 0.0007 0.0018
Schistosoma mansoni cathepsin F (C01 family) 0.3167 0.2334 0.6299
Toxoplasma gondii hypothetical protein 0.0027 0.0001 0.0002
Echinococcus granulosus tm gpcr rhodopsin 0.0049 0.0017 0.0046
Schistosoma mansoni adenoreceptor 0.0049 0.0017 0.0046
Echinococcus granulosus SAM and MBT domain containing protein 0.0038 0.0009 0.0023
Loa Loa (eye worm) hypothetical protein 0.0137 0.0082 0.0222
Onchocerca volvulus 0.0049 0.0017 0.0071
Echinococcus granulosus biogenic amine 5HT receptor 0.0049 0.0017 0.0046
Loa Loa (eye worm) hypothetical protein 0.0049 0.0017 0.0046
Loa Loa (eye worm) hypothetical protein 0.0028 0.0002 0.0005
Schistosoma mansoni SmCL2-like peptidase (C01 family) 0.1705 0.1248 0.3366
Brugia malayi ORL1-like opioid receptor 0.0049 0.0017 0.0046
Toxoplasma gondii pyruvate dehydrogenase kinase, putative 0.0095 0.0051 0.0219
Wolbachia endosymbiont of Brugia malayi (3R)-hydroxymyristoyl-ACP dehydratase 0.0061 0.0026 0.2259
Trypanosoma cruzi major cysteine proteinase, putative 0.1243 0.0905 0.2441
Brugia malayi Trypsin family protein 0.0172 0.0108 0.0292
Echinococcus multilocularis fmrfamide receptor 0.0049 0.0017 0.0046
Brugia malayi Nuclear hormone receptor family member nhr-19 0.003 0.0003 0.0007
Entamoeba histolytica cysteine protease, putative 0.0699 0.05 0.2141
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0049 0.0017 0.0046
Loa Loa (eye worm) PAN domain-containing protein 0.0027 0.0001 0.0002
Echinococcus multilocularis cadherin EGF LAG seven pass G type receptor 0.0698 0.0499 0.1347
Schistosoma mansoni ap endonuclease 0.0043 0.0012 0.0033
Onchocerca volvulus 0.0049 0.0017 0.0071
Brugia malayi gonadotropin-releasing hormone receptor 2 0.0049 0.0017 0.0046
Schistosoma mansoni peptide (FMRFamide/neurokinin-3)-like receptor 0.0049 0.0017 0.0046
Schistosoma mansoni hypothetical protein 0.0053 0.002 0.0053
Onchocerca volvulus 0.0062 0.0026 0.0111
Brugia malayi Cathepsin L-like cysteine proteinase 0.2161 0.1587 0.4281
Plasmodium vivax cysteine repeat modular protein 1, putative 0.0164 0.0103 0.0421
Echinococcus multilocularis glycoprotein Antigen 5 0.0244 0.0162 0.0436
Treponema pallidum fructose-bisphosphate aldolase 0.0208 0.0135 1
Brugia malayi Nuclear hormone receptor family member nhr-41 0.003 0.0003 0.0007
Schistosoma mansoni cercarial elastase (S01 family) 0.0172 0.0108 0.0292
Schistosoma mansoni aminoadipate-semialdehyde dehydrogenase 0.0062 0.0026 0.0071
Loa Loa (eye worm) reprolysin 0.0032 0.0004 0.0012
Mycobacterium tuberculosis Probable oxidoreductase 0.0091 0.0048 0.0889
Loa Loa (eye worm) fibroinase 0.3167 0.2334 0.6299
Mycobacterium ulcerans fructose-bisphosphate aldolase 0.0101 0.0056 0.0961
Trichomonas vaginalis Clan CA, family C1, papain-like cysteine peptidase 0.0699 0.05 0.2141
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0699 0.05 0.2141
Giardia lamblia Kinase, PLK 0.0053 0.002 0.0127
Onchocerca volvulus 0.0035 0.0007 0.0026
Echinococcus multilocularis microtubule associated protein 2 0.15 0.1095 0.2955
Trichomonas vaginalis Clan CA, family C1, papain-like cysteine peptidase 0.3167 0.2334 1
Entamoeba histolytica cysteine proteinase, putative 0.1705 0.1248 0.5344
Brugia malayi mbt repeat family protein 0.0038 0.0009 0.0023
Entamoeba histolytica fructose-1,6-bisphosphate aldolase, putative 0.0208 0.0135 0.0577
Echinococcus multilocularis G-protein coupled receptor, putative 0.0049 0.0017 0.0046
Loa Loa (eye worm) hypothetical protein 0.0049 0.0017 0.0046
Trichomonas vaginalis Clan CA, family C1, cathepsin L or H-like cysteine peptidase 0.0699 0.05 0.2141
Trypanosoma cruzi importin beta-1 subunit, putative 0.0056 0.0022 0.0059
Onchocerca volvulus Bile acid receptor homolog 0.003 0.0003 0.0009
Loa Loa (eye worm) hypothetical protein 0.0051 0.0018 0.005
Toxoplasma gondii ATPase/histidine kinase/DNA gyrase B/HSP90 domain-containing protein 0.011 0.0062 0.0267
Echinococcus multilocularis nmda type glutamate receptor 0.0052 0.0019 0.0051
Loa Loa (eye worm) hypothetical protein 0.3167 0.2334 0.6299
Leishmania major protein kinase, putative,polo-like protein kinase, putative 0.0053 0.002 0.0074
Leishmania major apurinic/apyrimidinic endonuclease-redox protein 0.0043 0.0012 0.0045
Plasmodium vivax dipeptidyl aminopeptidase 2, putative 0.0914 0.066 0.2814
Echinococcus multilocularis short transient receptor potential channel 6 0.0091 0.0048 0.0129
Loa Loa (eye worm) hypothetical protein 0.0053 0.002 0.0053
Loa Loa (eye worm) hypothetical protein 0.0049 0.0017 0.0046
Echinococcus multilocularis regulator of G protein signaling 7 0.0034 0.0005 0.0015
Onchocerca volvulus 0.0049 0.0017 0.0071
Echinococcus multilocularis serotonin receptor 0.0049 0.0017 0.0046
Brugia malayi Cathepsin L-like precursor 0.2161 0.1587 0.4281
Echinococcus granulosus microtubule associated protein 2 0.15 0.1095 0.2955
Brugia malayi PAN domain containing protein 0.0027 0.0001 0.0002
Leishmania major cathepsin L-like protease 0.3167 0.2334 0.8522
Echinococcus granulosus phosphatidylinositol 5 phosphate 4 kinase type 2 0.0094 0.005 0.0135
Echinococcus granulosus glutamate receptor ionotrophic AMPA 3 0.003 0.0002 0.0007
Schistosoma mansoni cathepsin B-like peptidase (C01 family) 0.0699 0.05 0.1348
Plasmodium vivax ataxin-2 like protein, putative 0.0201 0.013 0.0539
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.3712 0.274 1
Echinococcus granulosus Mastin 0.0244 0.0162 0.0436
Echinococcus granulosus lamin 0.0038 0.0009 0.0024
Schistosoma mansoni GTP-binding protein (I) alpha-2 subunit gnai2 0.0035 0.0007 0.0018
Loa Loa (eye worm) hypothetical protein 0.0049 0.0017 0.0046
Schistosoma mansoni SmCB2 peptidase (C01 family) 0.5012 0.3706 1
Loa Loa (eye worm) hypothetical protein 0.0169 0.0106 0.0287
Echinococcus multilocularis endonuclease exonuclease phosphatase 0.0158 0.0098 0.0264
Onchocerca volvulus 0.0049 0.0017 0.0071
Entamoeba histolytica serine/threonine protein kinase, putative 0.0053 0.002 0.0086
Mycobacterium tuberculosis Putative ferredoxin reductase 0.0081 0.0041 0.0742
Brugia malayi MH2 domain containing protein 0.0082 0.0041 0.0112
Schistosoma mansoni cercarial elastase (S01 family) 0.0172 0.0108 0.0292
Echinococcus granulosus 7TM GPCR rhodopsin 0.0049 0.0017 0.0046
Echinococcus multilocularis glutamate receptor, ionotrophic, AMPA 3 0.003 0.0002 0.0007
Onchocerca volvulus 0.0532 0.0376 0.1609
Loa Loa (eye worm) hypothetical protein 0.0698 0.0499 0.1347
Echinococcus granulosus neuropeptide receptor 0.0049 0.0017 0.0046
Trypanosoma cruzi apurinic/apyrimidinic endonuclease, putative 0.0043 0.0012 0.0033
Brugia malayi Matrixin family protein 0.0536 0.0379 0.1022
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0049 0.0017 0.0046
Echinococcus granulosus mothers against decapentaplegic 2 0.0082 0.0041 0.0112
Trypanosoma cruzi cysteine peptidase, putative 0.1006 0.0728 0.1965
Schistosoma mansoni GTP-binding protein alpha subunit 0.0035 0.0007 0.0018
Entamoeba histolytica cysteine proteinase, putative 0.2161 0.1587 0.6797
Echinococcus multilocularis guanine nucleotide binding protein G(s) subunit 0.082 0.059 0.1593
Loa Loa (eye worm) hypothetical protein 0.0049 0.0017 0.0046
Loa Loa (eye worm) hypothetical protein 0.0053 0.002 0.0053
Entamoeba histolytica cysteine proteinase, putative 0.3167 0.2334 1
Giardia lamblia Cathepsin B precursor 0.0699 0.05 0.3345
Echinococcus granulosus laminin 0.0051 0.0018 0.0049
Echinococcus granulosus hepatocyte nuclear factor 4 alpha 0.003 0.0003 0.0007
Echinococcus multilocularis glutathione S transferase 0.0217 0.0142 0.0383
Echinococcus multilocularis Transcription factor, JmjC domain containing protein 0.0043 0.0012 0.0033
Echinococcus multilocularis tachykinin peptides receptor 99D 0.0049 0.0017 0.0046
Schistosoma mansoni neuropeptide F-like receptor 0.0049 0.0017 0.0046
Plasmodium falciparum thioredoxin reductase 0.0036 0.0007 0.0025
Brugia malayi Nuclear hormone receptor family member nhr-49 0.003 0.0003 0.0007
Echinococcus multilocularis tm gpcr rhodopsin gpcr rhodopsin superfamily 0.0049 0.0017 0.0046
Schistosoma mansoni Smad4 0.0082 0.0041 0.0112
Echinococcus granulosus rhodopsin orphan GPCR 0.0049 0.0017 0.0046
Loa Loa (eye worm) RNA recognition domain-containing protein domain-containing protein 0.0444 0.0311 0.0838
Plasmodium falciparum cysteine proteinase falcipain 2a 0.3167 0.2334 1
Echinococcus multilocularis serine:threonine protein kinase PLK1 0.0053 0.002 0.0054
Schistosoma mansoni phosphatidylinositol-4-phosphate 5-kinase type II 0.0094 0.005 0.0135
Schistosoma mansoni bromodomain containing protein 0.0052 0.0019 0.0052
Brugia malayi Dopamine receptor protein 1, putative (partial) 0.0049 0.0017 0.0046
Plasmodium falciparum dipeptidyl aminopeptidase 2 0.0914 0.066 0.2824
Loa Loa (eye worm) hypothetical protein 0.2161 0.1587 0.4281
Toxoplasma gondii calcium binding egf domain-containing protein 0.0051 0.0018 0.0078
Echinococcus multilocularis neurogenic locus protein delta 0.0053 0.002 0.0053
Mycobacterium tuberculosis Probable NADH dehydrogenase Ndh 0.0081 0.0041 0.0742
Loa Loa (eye worm) hypothetical protein 0.0338 0.0232 0.0626
Toxoplasma gondii cathepsin B 0.2033 0.1492 0.6389
Plasmodium falciparum AP endonuclease (DNA-[apurinic or apyrimidinic site] lyase), putative 0.0043 0.0012 0.0047
Plasmodium falciparum dipeptidyl aminopeptidase 1 0.0914 0.066 0.2824
Loa Loa (eye worm) hypothetical protein 0.0053 0.002 0.0053
Loa Loa (eye worm) TYRA-2 protein 0.0049 0.0017 0.0046
Schistosoma mansoni hypothetical protein 0.0053 0.002 0.0053
Schistosoma mansoni biogenic amine receptor 0.0049 0.0017 0.0046
Plasmodium falciparum serine repeat antigen 5 0.0699 0.05 0.2136
Mycobacterium tuberculosis Probable ATP-dependent CLP protease proteolytic subunit 1 ClpP1 (endopeptidase CLP) 0.008 0.004 0.0714
Loa Loa (eye worm) hypothetical protein 0.0316 0.0216 0.0582
Loa Loa (eye worm) hypothetical protein 0.0532 0.0376 0.1015
Brugia malayi RNA, U transporter 1 0.0195 0.0125 0.0338
Toxoplasma gondii microneme protein MIC4 0.0027 0.0001 0.0002
Schistosoma mansoni cathepsin F (C01 family) 0.3167 0.2334 0.6299
Brugia malayi neuropeptide F receptor 0.0049 0.0017 0.0046
Loa Loa (eye worm) hypothetical protein 0.0053 0.002 0.0053
Schistosoma mansoni jumonji/arid domain-containing protein 0.0047 0.0015 0.0041
Schistosoma mansoni smad 0.0082 0.0041 0.0112
Brugia malayi cathepsin L-like cysteine proteinase 0.0699 0.05 0.1348
Loa Loa (eye worm) hypothetical protein 0.0536 0.0379 0.1022
Schistosoma mansoni hypothetical protein 0.076 0.0545 0.1471
Entamoeba histolytica hypothetical protein 0.0119 0.0069 0.0296
Schistosoma mansoni neuropeptide receptor 0.0049 0.0017 0.0046
Schistosoma mansoni histamine h1 receptor 0.0049 0.0017 0.0046
Brugia malayi Calcium binding EGF domain containing protein 0.0053 0.002 0.0053
Echinococcus granulosus GA binding protein alpha chain 0.0034 0.0006 0.0016
Echinococcus granulosus FTZ F1 alpha 0.003 0.0003 0.0007
Loa Loa (eye worm) RNA binding protein 0.0444 0.0311 0.0838
Entamoeba histolytica hypothetical protein 0.0119 0.0069 0.0296
Echinococcus granulosus histone acetyltransferase KAT2B 0.0101 0.0056 0.015
Trichomonas vaginalis conserved hypothetical protein 0.0699 0.05 0.2141
Schistosoma mansoni cathepsin B-like peptidase (C01 family) 0.5012 0.3706 1
Echinococcus multilocularis glutathione S transferase 0.0064 0.0028 0.0075
Brugia malayi Guanine nucleotide-binding protein alpha-3 subunit, putative 0.0035 0.0007 0.0018
Schistosoma mansoni SmCL2-like peptidase (C01 family) 0.1705 0.1248 0.3366
Loa Loa (eye worm) hypothetical protein 0.0699 0.05 0.1348
Brugia malayi EGF-like domain containing protein 0.0053 0.002 0.0053
Giardia lamblia Cathepsin B precursor 0.2033 0.1492 1
Plasmodium vivax dipeptidyl aminopeptidase 3, putative 0.078 0.0561 0.2387
Echinococcus granulosus cathepsin b 0.5012 0.3706 1
Schistosoma mansoni cathepsin F (C01 family) 0.2161 0.1587 0.4281
Giardia lamblia Cathepsin L precursor 0.0699 0.05 0.3345
Echinococcus granulosus protein jagged 1 0.0053 0.002 0.0053
Brugia malayi MH1 domain containing protein 0.0101 0.0056 0.015
Entamoeba histolytica hypothetical protein 0.0119 0.0069 0.0296
Loa Loa (eye worm) jmjC domain-containing protein 0.0047 0.0015 0.0041
Echinococcus granulosus suppression of tumorigenicity 18 protein 0.0043 0.0013 0.0034
Trypanosoma cruzi cysteine peptidase, putative 0.1705 0.1248 0.3366
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.3167 0.2334 1
Brugia malayi TAR-binding protein 0.0444 0.0311 0.0838
Onchocerca volvulus 0.0049 0.0017 0.0071
Brugia malayi Glycosyl hydrolases family 31 protein 0.0118 0.0068 0.0184
Loa Loa (eye worm) matrixin family protein 0.1188 0.0864 0.2331
Loa Loa (eye worm) hypothetical protein 0.0699 0.05 0.1348
Entamoeba histolytica cysteine proteinase 1, putative 0.1705 0.1248 0.5344
Echinococcus multilocularis cathepsin L 0.1705 0.1248 0.3366
Plasmodium falciparum importin beta, putative 0.0068 0.0031 0.0129
Echinococcus granulosus slit 2 protein 0.006 0.0025 0.0068
Plasmodium vivax isocitrate dehydrogenase [NADP], mitochondrial, putative 0.0169 0.0106 0.0437
Echinococcus granulosus glutathione S transferase 0.0064 0.0028 0.0075
Echinococcus granulosus TRP transient receptor potential channel 0.0051 0.0018 0.005
Echinococcus granulosus a disintegrin and metalloproteinase with 0.0123 0.0072 0.0195
Onchocerca volvulus 0.0049 0.0017 0.0071
Echinococcus granulosus FTZ F1 nuclear receptor protein 0.003 0.0003 0.0007
Loa Loa (eye worm) hypothetical protein 0.0699 0.05 0.1348
Giardia lamblia Cysteine protease 0.0699 0.05 0.3345
Loa Loa (eye worm) low-density lipoprotein receptor repeat class B containing protein 0.0051 0.0018 0.0049
Toxoplasma gondii microneme protein MIC17C 0.0027 0.0001 0.0002
Echinococcus multilocularis glutamate receptor 2 0.003 0.0002 0.0007
Schistosoma mansoni cercarial elastase (S01 family) 0.0172 0.0108 0.0292
Onchocerca volvulus 0.0049 0.0017 0.0071
Schistosoma mansoni RAR-like nuclear receptor 0.003 0.0003 0.0007
Trichomonas vaginalis bromodomain-containing protein, putative 0.0032 0.0005 0.0019
Mycobacterium tuberculosis Dihydrolipoamide dehydrogenase LpdC (lipoamide reductase (NADH)) (lipoyl dehydrogenase) (dihydrolipoyl dehydrogenase) (diaphoras 0.0091 0.0048 0.0889
Mycobacterium tuberculosis Probable membrane NADH dehydrogenase NdhA 0.0081 0.0041 0.0742
Brugia malayi fibroinase precursor 0.0699 0.05 0.1348
Echinococcus multilocularis sex peptide receptor 0.0049 0.0017 0.0046
Echinococcus granulosus diuretic hormone 44 receptor GPRdih2 0.0698 0.0499 0.1347
Brugia malayi neuropeptide F receptor 0.0049 0.0017 0.0046
Echinococcus granulosus endonuclease exonuclease phosphatase 0.0158 0.0098 0.0264
Trichomonas vaginalis Importin beta-1 subunit, putative 0.0056 0.0022 0.0093
Echinococcus multilocularis Nuclear hormone receptor family member nhr 41 0.003 0.0003 0.0007
Loa Loa (eye worm) hypothetical protein 0.0049 0.0017 0.0046
Echinococcus granulosus biogenic amine 5HT receptor 0.0049 0.0017 0.0046
Schistosoma mansoni cathepsin C 0.0699 0.05 0.1348
Loa Loa (eye worm) hypothetical protein 0.0049 0.0017 0.0046
Giardia lamblia High cysteine protein 0.0053 0.002 0.0123
Toxoplasma gondii microneme protein, putative 0.0027 0.0001 0.0002
Loa Loa (eye worm) hypothetical protein 0.0051 0.0018 0.0049
Entamoeba histolytica papain family cysteine protease domain containing protein 0.0699 0.05 0.2141
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.3712 0.274 1
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.1705 0.1248 0.4554
Onchocerca volvulus 0.0049 0.0017 0.0071
Echinococcus multilocularis slit 2 protein 0.006 0.0025 0.0068
Plasmodium vivax unspecified product 0.0699 0.05 0.2126
Schistosoma mansoni neuropeptide F-like receptor 0.0049 0.0017 0.0046
Loa Loa (eye worm) transcription factor SMAD2 0.2687 0.1978 0.5336
Trichomonas vaginalis fructose-bisphosphate aldolase, putative 0.0208 0.0135 0.0577
Brugia malayi GTP-binding regulatory protein Gs alpha-S chain, putative 0.082 0.059 0.1593
Echinococcus multilocularis rhodopsin orphan GPCR 0.0049 0.0017 0.0046
Brugia malayi Corticotropin releasing factor receptor 2 precursor, putative 0.2205 0.1619 0.4369
Loa Loa (eye worm) hypothetical protein 0.0049 0.0017 0.0046
Brugia malayi putative neuropeptide receptor 0.0049 0.0017 0.0046
Trichomonas vaginalis CAMK family protein kinase 0.0053 0.002 0.0086
Echinococcus granulosus transient receptor potential gamma protein 0.0137 0.0082 0.0222
Mycobacterium tuberculosis NAD(P)H quinone reductase LpdA 0.0091 0.0048 0.0889
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.3712 0.274 1
Schistosoma mansoni notch 0.0053 0.002 0.0053
Schistosoma mansoni peptide (FMRFamide/somatostatin)-like receptor 0.0049 0.0017 0.0046
Echinococcus granulosus ecdysone induced protein 78C 0.003 0.0003 0.0007
Leishmania major cysteine peptidase C (CPC),CPC cysteine peptidase, Clan CA, family C1, Cathepsin B-like 0.2033 0.1492 0.5444
Toxoplasma gondii aldehyde dehydrogenase 0.0093 0.005 0.0212
Loa Loa (eye worm) hypothetical protein 0.0034 0.0005 0.0015
Brugia malayi G-protein coupled receptor 0.0049 0.0017 0.0046
Echinococcus granulosus protein jagged 2 0.0053 0.002 0.0053
Loa Loa (eye worm) G protein signaling regulator EGL-10 0.0034 0.0005 0.0015
Schistosoma mansoni hypothetical protein 0.0698 0.0499 0.1347
Brugia malayi Trypsin-like protease protein 5 0.0172 0.0108 0.0292
Loa Loa (eye worm) hypothetical protein 0.0049 0.0017 0.0046
Echinococcus multilocularis neuropeptide Y receptor 0.0049 0.0017 0.0046
Schistosoma mansoni hypothetical protein 0.0053 0.002 0.0053
Loa Loa (eye worm) hypothetical protein 0.0035 0.0007 0.0018
Echinococcus granulosus g protein coupled receptor 0.0049 0.0017 0.0046
Chlamydia trachomatis ATP-dependent Clp protease proteolytic subunit 0.0122 0.0071 0.0046
Brugia malayi cathepsin B-like cysteine proteinase 0.5012 0.3706 1
Giardia lamblia Cathepsin L precursor 0.0699 0.05 0.3345
Loa Loa (eye worm) hypothetical protein 0.0172 0.0108 0.0292
Loa Loa (eye worm) nucleolar RNA-associated protein alpha 0.0731 0.0524 0.1414
Brugia malayi Kringle domain containing protein 0.0164 0.0103 0.0277
Entamoeba histolytica cysteine protease, putative 0.1705 0.1248 0.5344
Giardia lamblia Endonuclease/Exonuclease/phosphatase 0.0043 0.0012 0.0074
Mycobacterium ulcerans aldehyde dehydrogenase 0.0093 0.005 0.0822
Schistosoma mansoni hypothetical protein 0.0239 0.0158 0.0427
Loa Loa (eye worm) hypothetical protein 0.0027 0.0001 0.0002
Brugia malayi hypothetical protein 0.0172 0.0108 0.0292
Loa Loa (eye worm) hypothetical protein 0.0094 0.005 0.0135
Plasmodium vivax vivapain-3 0.1705 0.1248 0.5335
Echinococcus multilocularis g protein linked acetylcholine receptor gar 2a 0.0049 0.0017 0.0046
Toxoplasma gondii PAN domain-containing protein 0.0027 0.0001 0.0002
Echinococcus multilocularis protein jagged 1 0.0053 0.002 0.0053
Loa Loa (eye worm) hypothetical protein 0.0053 0.002 0.0053
Loa Loa (eye worm) gonadotropin-releasing hormone receptor 2 0.0049 0.0017 0.0046
Schistosoma mansoni hypothetical protein 0.0698 0.0499 0.1347
Schistosoma mansoni z-protein (S1r protein) 0.0034 0.0005 0.0015
Loa Loa (eye worm) hypothetical protein 0.0038 0.0009 0.0024
Brugia malayi Fibulin-1 precursor 0.0051 0.0018 0.0049
Loa Loa (eye worm) hypothetical protein 0.0049 0.0017 0.0046
Brugia malayi cathepsin Z-like cysteine proteinase 0.0819 0.0589 0.159
Schistosoma mansoni aldehyde dehydrogenase 0.0093 0.005 0.0134
Schistosoma mansoni cathepsin B-like peptidase (C01 family) 0.0699 0.05 0.1348
Schistosoma mansoni survival motor neuron protein 0.0035 0.0006 0.0017
Brugia malayi Intermediate filament tail domain containing protein 0.0038 0.0009 0.0024
Loa Loa (eye worm) glutaminase 0.0151 0.0093 0.025
Loa Loa (eye worm) intermediate filament protein 0.0038 0.0009 0.0024
Echinococcus granulosus segment polarity protein dishevelled 0.0034 0.0005 0.0015
Loa Loa (eye worm) hypothetical protein 0.0049 0.0017 0.0046
Loa Loa (eye worm) hypothetical protein 0.0536 0.0379 0.1022
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0049 0.0017 0.0046
Schistosoma mansoni hypothetical protein 0.0049 0.0017 0.0046
Echinococcus multilocularis aldehyde dehydrogenase, mitochondrial 0.0093 0.005 0.0134
Loa Loa (eye worm) multiple epidermal growth factor-like domains 6 0.0051 0.0018 0.0049
Chlamydia trachomatis ATP-dependent Clp protease proteolytic subunit 0.0122 0.0071 0.0046
Trichomonas vaginalis fructose-bisphosphate aldolase, putative 0.0208 0.0135 0.0577
Loa Loa (eye worm) hypothetical protein 0.0049 0.0017 0.0046
Loa Loa (eye worm) hypothetical protein 0.0172 0.0108 0.0292
Echinococcus granulosus mothers against decapentaplegic 5 0.0183 0.0117 0.0315
Loa Loa (eye worm) hypothetical protein 0.2161 0.1587 0.4281
Schistosoma mansoni notch 0.0053 0.002 0.0053
Schistosoma mansoni neuropeptide receptor 0.0049 0.0017 0.0046
Brugia malayi Protein kinase domain containing protein 0.0164 0.0103 0.0277
Echinococcus granulosus guanine nucleotide binding protein Gs subunit 0.082 0.059 0.1593
Brugia malayi photoreceptor-specific nuclear receptor 0.003 0.0003 0.0007
Loa Loa (eye worm) hypothetical protein 0.0172 0.0108 0.0292
Trichomonas vaginalis ap endonuclease, putative 0.0043 0.0012 0.0053
Echinococcus granulosus rhodopsin orphan GPCR 0.0049 0.0017 0.0046
Trypanosoma cruzi cysteine peptidase, putative 0.3167 0.2334 0.6299
Onchocerca volvulus Matrilysin homolog 0.1188 0.0864 0.3699
Trichomonas vaginalis GTP-binding protein alpha subunit, gna, putative 0.0035 0.0007 0.0029
Brugia malayi EGF-like domain containing protein 0.0053 0.002 0.0053
Onchocerca volvulus 0.3167 0.2334 1
Brugia malayi follicle stimulating hormone receptor 0.0115 0.0066 0.0178
Echinococcus granulosus adam 0.0067 0.003 0.0082
Toxoplasma gondii cathepsin CPL 0.3167 0.2334 1
Schistosoma mansoni amine GPCR 0.0049 0.0017 0.0046
Schistosoma mansoni sodium/chloride dependent transporter 0.0054 0.0021 0.0056
Schistosoma mansoni cathepsin B (C01 family) 0.0699 0.05 0.1348
Giardia lamblia Cysteine protease 0.0699 0.05 0.3345
Plasmodium vivax glutathione S-transferase, putative 0.0281 0.0189 0.0794
Schistosoma mansoni neuropeptide receptor 0.0049 0.0017 0.0046
Brugia malayi cathepsin F-like cysteine proteinase 0.0699 0.05 0.1348
Echinococcus granulosus smad 0.0183 0.0117 0.0315
Mycobacterium leprae Probable fructose bisphosphate aldolase Fba 0.0101 0.0056 0.0974
Loa Loa (eye worm) hypothetical protein 0.0053 0.002 0.0053
Onchocerca volvulus Mothers against decapentaplegic homolog 0.0082 0.0041 0.0175
Loa Loa (eye worm) pigment dispersing factor receptor c 0.2205 0.1619 0.4369
Echinococcus multilocularis g protein coupled receptor 0.0049 0.0017 0.0046
Brugia malayi Melatonin receptor type 1A 0.0049 0.0017 0.0046
Brugia malayi Delta serrate ligand family protein 0.0053 0.002 0.0053
Loa Loa (eye worm) TK/ROR protein kinase 0.0164 0.0103 0.0277
Echinococcus granulosus rhodopsin orphan GPCR 0.0049 0.0017 0.0046
Echinococcus multilocularis nmda type glutamate receptor 0.0054 0.002 0.0055
Loa Loa (eye worm) papain family cysteine protease containing protein 0.1006 0.0728 0.1965
Trypanosoma brucei importin beta-1 subunit, putative 0.0068 0.0031 0.0115
Schistosoma mansoni pyruvate dehydrogenase 0.0271 0.0182 0.0492
Loa Loa (eye worm) hypothetical protein 0.0049 0.0017 0.0046
Trypanosoma cruzi major cysteine proteinase, putative 0.0699 0.05 0.1348
Loa Loa (eye worm) hypothetical protein 0.0062 0.0026 0.0071
Trypanosoma cruzi trypanothione reductase, putative 0.0036 0.0007 0.0019
Echinococcus multilocularis fmrfamide receptor 0.0049 0.0017 0.0046
Echinococcus granulosus short transient receptor potential channel 6 0.0091 0.0048 0.0129
Loa Loa (eye worm) hypothetical protein 0.0027 0.0001 0.0002
Plasmodium falciparum glutathione S-transferase 0.0064 0.0028 0.0114
Toxoplasma gondii histone lysine acetyltransferase GCN5-B 0.0032 0.0005 0.0019
Echinococcus granulosus rhodopsin orphan GPCR 0.0049 0.0017 0.0046
Trichomonas vaginalis G protein (olf) alpha subunit, gnal, putative 0.0035 0.0007 0.0029
Toxoplasma gondii ATP-dependent Clp endopeptidase, proteolytic subunit ClpP domain-containing protein 0.0122 0.0071 0.0304
Onchocerca volvulus 0.0049 0.0017 0.0071
Leishmania major cathepsin L-like protease 0.3167 0.2334 0.8522
Trypanosoma cruzi polo-like protein kinase, putative 0.0053 0.002 0.0054
Loa Loa (eye worm) mbt repeat family protein 0.0038 0.0009 0.0023
Echinococcus granulosus lysosomal alpha glucosidase 0.0118 0.0068 0.0184
Loa Loa (eye worm) hypothetical protein 0.0699 0.05 0.1348
Loa Loa (eye worm) G-protein coupled receptor 0.0049 0.0017 0.0046
Echinococcus multilocularis tumor protein p63 0.0231 0.0152 0.0411
Loa Loa (eye worm) hypothetical protein 0.0049 0.0017 0.0046
Schistosoma mansoni alpha-glucosidase 0.0102 0.0056 0.0151
Brugia malayi Integrin beta pat-3 precursor 0.016 0.0099 0.0268
Echinococcus granulosus nuclear receptor 2DBD gamma 0.003 0.0003 0.0007
Schistosoma mansoni hypothetical protein 0.0698 0.0499 0.1347
Brugia malayi Low-density lipoprotein receptor repeat class B containing protein 0.0051 0.0018 0.0049
Echinococcus granulosus glycoprotein Antigen 5 0.0244 0.0162 0.0436
Echinococcus multilocularis diuretic hormone 44 receptor GPRdih2 0.0698 0.0499 0.1347
Echinococcus granulosus DNA apurinic or apyrimidinic site lyase 0.0043 0.0012 0.0033
Echinococcus granulosus regulator of G protein signaling 7 0.0034 0.0005 0.0015
Brugia malayi Glutathione S-transferase 4 0.0049 0.0017 0.0046
Leishmania major cathepsin L-like protease 0.3712 0.274 1
Trichomonas vaginalis Clan CA, family C1, cathepsin L, S or H-like cysteine peptidase 0.0699 0.05 0.2141
Echinococcus granulosus guanine nucleotide binding protein Gs subunit 0.082 0.059 0.1593
Loa Loa (eye worm) hypothetical protein 0.0049 0.0017 0.0046
Schistosoma mansoni subfamily C1A unassigned peptidase (C01 family) 0.0699 0.05 0.1348
Loa Loa (eye worm) hypothetical protein 0.0051 0.0018 0.0049
Echinococcus multilocularis cathepsin b 0.5012 0.3706 1
Echinococcus multilocularis FTZ F1 alpha 0.003 0.0003 0.0007
Trichomonas vaginalis CAMK family protein kinase 0.0053 0.002 0.0086
Echinococcus granulosus glutathione S transferase Mu 1 0.0064 0.0028 0.0075
Echinococcus multilocularis lysosomal alpha glucosidase 0.0118 0.0068 0.0184
Echinococcus granulosus pyroglutamylated rfamide peptide receptor 0.0049 0.0017 0.0046
Loa Loa (eye worm) hypothetical protein 0.0029 0.0002 0.0006
Schistosoma mansoni kinase 0.0027 0.0001 0.0002
Echinococcus granulosus adam 17 protease 0.0166 0.0104 0.028
Schistosoma mansoni hypothetical protein 0.0559 0.0396 0.1069
Loa Loa (eye worm) hypothetical protein 0.0136 0.0082 0.0221
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.3167 0.2334 1
Schistosoma mansoni hypothetical protein 0.009 0.0048 0.0129
Toxoplasma gondii thioredoxin reductase 0.0036 0.0007 0.003
Trichomonas vaginalis glutaminase, putative 0.0151 0.0093 0.0398
Echinococcus granulosus tar DNA binding protein 0.0444 0.0311 0.0838
Plasmodium vivax importin-beta 2, putative 0.0068 0.0031 0.0115
Toxoplasma gondii PAN domain-containing protein 0.0027 0.0001 0.0002
Brugia malayi RNA binding protein 0.0444 0.0311 0.0838
Brugia malayi Isocitrate dehydrogenase 0.0169 0.0106 0.0287
Trypanosoma cruzi cysteine proteinase, putative 0.1705 0.1248 0.3366
Brugia malayi regulator of G-protein signaling egl-10 0.0034 0.0005 0.0015
Echinococcus multilocularis neural cadherin 0.0053 0.002 0.0053
Leishmania major isocitrate dehydrogenase [NADP], mitochondrial precursor, putative 0.0169 0.0106 0.0388
Schistosoma mansoni microtubule-associated protein tau 0.15 0.1095 0.2955
Schistosoma mansoni adam (A disintegrin and metalloprotease 0.0062 0.0027 0.0072
Toxoplasma gondii hypothetical protein 0.0027 0.0001 0.0002
Onchocerca volvulus 0.0049 0.0017 0.007
Schistosoma mansoni Tr4/Tr2 (homologue) 0.003 0.0003 0.0007
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0699 0.05 0.2141
Loa Loa (eye worm) hypothetical protein 0.0049 0.0017 0.0046
Loa Loa (eye worm) neuropeptide F receptor 0.0049 0.0017 0.0046
Entamoeba histolytica cysteine protease, putative 0.1705 0.1248 0.5344
Toxoplasma gondii histone lysine acetyltransferase GCN5-A 0.0032 0.0005 0.0019
Echinococcus multilocularis peptidase Clp (S14 family) 0.008 0.004 0.0107
Trichomonas vaginalis Clan CA, family C1, papain-like cysteine peptidase 0.0819 0.0589 0.2524
Echinococcus multilocularis segment polarity protein dishevelled 0.0034 0.0005 0.0015
Echinococcus multilocularis neuropeptide FF receptor 2 0.0188 0.012 0.0325
Echinococcus granulosus metabotropic glutamate receptor 5 0.0033 0.0005 0.0013
Trichomonas vaginalis conserved hypothetical protein 0.0699 0.05 0.2141
Echinococcus multilocularis bromodomain adjacent to zinc finger domain 0.0027 0 0.0001
Treponema pallidum exodeoxyribonuclease (exoA) 0.0043 0.0012 0.0052
Loa Loa (eye worm) hypothetical protein 0.003 0.0003 0.0008
Echinococcus multilocularis expressed protein 0.0035 0.0007 0.0018
Schistosoma mansoni hypothetical protein 0.0172 0.0108 0.0292
Schistosoma mansoni cathepsin B-like peptidase (C01 family) 0.0699 0.05 0.1348
Echinococcus granulosus intermediate filament protein 0.0038 0.0009 0.0024
Mycobacterium tuberculosis Probable peptidoglycan hydrolase 0.0653 0.0466 1
Brugia malayi EGF-like domain containing protein 0.006 0.0025 0.0068
Brugia malayi Calcitonin receptor-like protein seb-1 0.2205 0.1619 0.4369
Echinococcus multilocularis polycomb protein SCMH1 0.0038 0.0009 0.0023
Echinococcus multilocularis mothers against decapentaplegic 2 0.0082 0.0041 0.0112
Onchocerca volvulus 0.0053 0.002 0.0082
Brugia malayi hypothetical protein 0.0201 0.013 0.0351
Giardia lamblia Cathepsin L precursor 0.0699 0.05 0.3345
Echinococcus granulosus cathepsin L 0.0699 0.05 0.1348
Trichomonas vaginalis GTP-binding protein alpha subunit, gna, putative 0.0035 0.0007 0.0029
Schistosoma mansoni thyroid hormone receptor 0.003 0.0003 0.0007
Trichomonas vaginalis GTP-binding protein alpha subunit, gna, putative 0.0035 0.0007 0.0029
Echinococcus multilocularis NADP dependent isocitrate dehydrogenase 0.0169 0.0106 0.0287
Echinococcus multilocularis regulator of G protein signaling 7 0.0034 0.0005 0.0015
Echinococcus multilocularis lysosomal alpha glucosidase 0.0118 0.0068 0.0184
Echinococcus multilocularis somatostatin receptor 0.0049 0.0017 0.0046
Onchocerca volvulus Rap guanine nucleotide exchange factor 1 homolog 0.0681 0.0487 0.2084
Echinococcus granulosus sodium and chloride dependent glycine 0.0054 0.0021 0.0056
Loa Loa (eye worm) melatonin receptor type 1A 0.0049 0.0017 0.0046
Loa Loa (eye worm) glutaminase 2 0.0151 0.0093 0.025
Loa Loa (eye worm) hypothetical protein 0.0049 0.0017 0.0046
Brugia malayi hypothetical protein 0.0034 0.0005 0.0015
Echinococcus multilocularis G protein coupled receptor 139 0.0049 0.0017 0.0046
Echinococcus multilocularis nuclear receptor 2DBD gamma 0.003 0.0003 0.0007
Onchocerca volvulus 0.3167 0.2334 1
Brugia malayi Papain family cysteine protease containing protein 0.3167 0.2334 0.6299
Trypanosoma cruzi cysteine peptidase, putative 0.3712 0.274 0.7391
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0049 0.0017 0.0046
Schistosoma mansoni Pro-neuregulin-4 membrane-bound isoform (Pro-NRG4) [Contains: Neuregulin-4 (NRG-4)] 0.0053 0.002 0.0053
Schistosoma mansoni integrin beta subunit 0.0094 0.005 0.0136
Loa Loa (eye worm) PAN domain-containing protein 0.0027 0.0001 0.0002
Echinococcus granulosus tm gpcr rhodopsin 0.0049 0.0017 0.0046
Loa Loa (eye worm) hypothetical protein 0.0049 0.0017 0.0046
Trichomonas vaginalis fructose-bisphosphate aldolase, putative 0.0208 0.0135 0.0577
Loa Loa (eye worm) hypothetical protein 0.003 0.0003 0.0007
Entamoeba histolytica cysteine protease, putative 0.1705 0.1248 0.5344
Onchocerca volvulus 0.0034 0.0006 0.0022
Brugia malayi larval opioid receptor 0.0049 0.0017 0.0046
Onchocerca volvulus Matrix metalloproteinase homolog 0.1188 0.0864 0.3699
Trichomonas vaginalis ap endonuclease, putative 0.0043 0.0012 0.0053
Brugia malayi Cadherin domain containing protein 0.0053 0.002 0.0053
Trypanosoma cruzi DNA polymerase eta, putative 0.0038 0.0008 0.0023
Loa Loa (eye worm) hypothetical protein 0.0046 0.0015 0.004
Onchocerca volvulus 0.0049 0.0017 0.0071
Echinococcus multilocularis phosphatidylinositol 5 phosphate 4 kinase type 2 0.0094 0.005 0.0135
Mycobacterium ulcerans ATP-dependent Clp protease proteolytic subunit 0.0122 0.0071 0.1294
Loa Loa (eye worm) hypothetical protein 0.0049 0.0017 0.0046
Trichomonas vaginalis Clan CA, family C1, papain-like cysteine peptidase 0.0699 0.05 0.2141
Echinococcus granulosus tm gpcr rhodopsin 0.0049 0.0017 0.0046
Echinococcus multilocularis glutathione S transferase 0.0064 0.0028 0.0075
Loa Loa (eye worm) MH1 domain-containing protein 0.0082 0.0041 0.0112
Echinococcus granulosus mothers against decapentaplegic 6 0.0082 0.0041 0.0112
Trichomonas vaginalis GTP-binding protein (z) alpha subunit, gnaz, putative 0.0035 0.0007 0.0029
Echinococcus multilocularis g protein coupled receptor 0.0049 0.0017 0.0046
Mycobacterium tuberculosis Probable dehydrogenase 0.0081 0.0041 0.0742
Echinococcus granulosus cpg binding protein 0.0049 0.0017 0.0045
Loa Loa (eye worm) hypothetical protein 0.0049 0.0017 0.0046
Trypanosoma cruzi hypothetical protein, conserved 0.0164 0.0103 0.0277
Plasmodium vivax serine-repeat antigen 2 (SERA) 0.0699 0.05 0.2126
Brugia malayi ADAM-TS Spacer 1 family protein 0.0136 0.0082 0.0221
Echinococcus multilocularis hepatocyte nuclear factor 4 alpha 0.003 0.0003 0.0007
Loa Loa (eye worm) papain family cysteine protease containing protein 0.0699 0.05 0.1348
Brugia malayi guanine nucleotide-binding protein G-o protein alpha subunit 0.0035 0.0007 0.0018
Plasmodium falciparum serine repeat antigen 6 0.0699 0.05 0.2136
Loa Loa (eye worm) hypothetical protein 0.0054 0.0021 0.0056
Brugia malayi mbt repeat family protein 0.0038 0.0009 0.0023
Brugia malayi Guanine nucleotide-binding protein alpha-12 subunit, putative 0.0035 0.0007 0.0018
Brugia malayi Dopamine receptor 0.0049 0.0017 0.0046
Echinococcus multilocularis transient receptor potential gamma protein 0.0137 0.0082 0.0222
Schistosoma mansoni hypothetical protein 0.0304 0.0206 0.0557
Brugia malayi N-terminal motif family protein 0.0681 0.0487 0.1314
Echinococcus multilocularis neuropeptide receptor 0.0049 0.0017 0.0046
Entamoeba histolytica hypothetical protein 0.0699 0.05 0.2141
Brugia malayi hypothetical protein 0.0034 0.0005 0.0015
Echinococcus granulosus transient receptor potential ion channel A 0.0132 0.0079 0.0213
Brugia malayi Matrixin family protein 0.0536 0.0379 0.1022
Plasmodium vivax ATP-dependent Clp protease proteolytic subunit, putative 0.0122 0.0071 0.0285
Echinococcus multilocularis rhodopsin orphan GPCR 0.0049 0.0017 0.0046
Giardia lamblia Cathepsin L-like protease 0.0699 0.05 0.3345
Schistosoma mansoni cercarial elastase (S01 family) 0.0172 0.0108 0.0292
Loa Loa (eye worm) unidentified vitellogenin-linked transcript protein 6 0.0049 0.0017 0.0046
Loa Loa (eye worm) DIX domain-containing protein 0.0034 0.0005 0.0015
Loa Loa (eye worm) hypothetical protein 0.0043 0.0013 0.0034
Echinococcus granulosus neuropeptide Y receptor 0.0049 0.0017 0.0046
Echinococcus multilocularis g protein coupled receptor 0.0049 0.0017 0.0046
Echinococcus granulosus neuropeptide FF receptor 2 0.0188 0.012 0.0325
Mycobacterium tuberculosis Probable fructose-bisphosphate aldolase Fba 0.0101 0.0056 0.1064
Loa Loa (eye worm) hypothetical protein 0.0035 0.0007 0.0018
Brugia malayi nuclear receptor NHR-88 0.003 0.0003 0.0007
Schistosoma mansoni hypothetical protein 0.0049 0.0017 0.0046
Echinococcus granulosus COUP TF:Svp nuclear hormone receptor 0.003 0.0003 0.0007

Activities

No activities found for this compound.

Phenotypes

Whole-cell/tissue/organism interactions

We have no records of whole-cell/tissue assays done with this compound What does this mean?

Many chemical entities in TDR Targets come from high-throughput screenings with whole cells or tissue samples, and not all assayed compounds have been tested against a single a single target protein, probably because they get ruled out during screening process. Even if these compounds may have not been of interest in the original screening, they may come as interesting leads for other screening assays. Furthermore, we may be able to propose drug-target associations using chemical similarities and network patterns.

Annotated phenotypes:

We have no manually annotated phenotypes for this drug. What does this mean? / Care to help?
In TDR Targets, information about phenotypes that are caused by drugs, or by genetic manipulation of cells (e.g. gene knockouts or knockdowns) is manually curated from the literature. These descriptions help to describe the potential of the target for drug development. If no information is available for this gene or if the information is incomplete, this may mean that i) the papers containing this information either appeared after the curation effort for this organism was carried out or they were inadvertently missed by curators; or that ii) the curation effort for this organism has not yet started.
 
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External resources for this compound

Bibliographic References

No literature references available for this target.

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