Detailed information for compound 881493

Basic information

Technical information
  • TDR Targets ID: 881493
  • Name: 5-(3,4-dimethylphenyl)-6-methyl-3-prop-2-enyl thieno[3,2-e]pyrimidin-4-one
  • MW: 310.413 | Formula: C18H18N2OS
  • H donors: 0 H acceptors: 1 LogP: 4.3 Rotable bonds: 3
    Rule of 5 violations (Lipinski): 1
  • SMILES: C=CCn1cnc2c(c1=O)c(c1ccc(c(c1)C)C)c(s2)C
  • InChi: 1S/C18H18N2OS/c1-5-8-20-10-19-17-16(18(20)21)15(13(4)22-17)14-7-6-11(2)12(3)9-14/h5-7,9-10H,1,8H2,2-4H3
  • InChiKey: IMNPEPCEILTXIT-UHFFFAOYSA-N  


Substructure search Similarity search

Network

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Synonyms

  • 3-allyl-5-(3,4-dimethylphenyl)-6-methyl-thieno[3,2-e]pyrimidin-4-one
  • 3-allyl-5-(3,4-dimethylphenyl)-6-methyl-4-thieno[3,2-e]pyrimidinone
  • 5-(3,4-dimethylphenyl)-6-methyl-3-prop-2-enyl-thieno[3,2-e]pyrimidin-4-one
  • ST5028367
  • ZINC00149242
  • 3-Allyl-5-(3,4-dimethyl-phenyl)-6-methyl-3H-thieno[2,3-d]pyrimidin-4-one
  • BAS 08756556

Targets

Known targets for this compound

No curated genes were found associated with this compound

Predicted pathogen targets for this compound

By orthology
No druggable targets predicted by orthology data
By sequence similarity to non orthologous known druggable targets
No druggable targets predicted by sequence similarity
Obtained from network model

Ranking Plot

Putative Targets List

Species Potential target Raw Global Species
Trypanosoma brucei THT1 - hexose transporter, putative 0.0066 0.0608 0.1542
Trichomonas vaginalis sugar transport protein, putative 0.003 0.0203 0.0331
Schistosoma mansoni aldehyde dehydrogenase 0.0124 0.1257 0.1557
Plasmodium falciparum lysine--tRNA ligase 0.0048 0.0401 0.0399
Brugia malayi beta-lactamase family protein 0.0074 0.0693 0.1136
Loa Loa (eye worm) solute carrier family 6 member 4 0.0017 0.0053 0.0087
Schistosoma mansoni hypothetical protein 0.0524 0.5709 0.708
Trichomonas vaginalis sugar transporter, putative 0.003 0.0203 0.0331
Trypanosoma cruzi DNA polymerase eta, putative 0.0019 0.0078 0.0192
Loa Loa (eye worm) hypothetical protein 0.0024 0.0141 0.0231
Plasmodium falciparum transporter, putative 0.0017 0.0053 0.0051
Brugia malayi Carbonic anhydrase like protein 2 precursor 0.0171 0.1777 0.2918
Loa Loa (eye worm) hypothetical protein 0.0039 0.0306 0.0503
Schistosoma mansoni norepinephrine/norepinephrine transporter 0.0017 0.0053 0.0063
Giardia lamblia NADH oxidase lateral transfer candidate 0.0014 0.0024 0.0064
Loa Loa (eye worm) hypothetical protein 0.0074 0.0693 0.1139
Echinococcus granulosus geminin 0.0524 0.5709 0.7081
Loa Loa (eye worm) hypothetical protein 0.013 0.1323 0.2174
Brugia malayi glutamate-gated chloride channel alpha3A subunit, putative 0.0013 0.0015 0.0021
Brugia malayi Animal haem peroxidase family protein 0.0039 0.0306 0.05
Mycobacterium tuberculosis Conserved protein 0.0074 0.0693 0.1345
Toxoplasma gondii sugar transporter ST1 0.003 0.0203 0.0304
Schistosoma mansoni serine/threonine protein kinase 0.0096 0.094 0.1163
Mycobacterium tuberculosis Probable cytochrome P450 141 Cyp141 0.0039 0.0306 0.0592
Mycobacterium tuberculosis Probable cytochrome P450 124 Cyp124 0.0039 0.0306 0.0592
Schistosoma mansoni tar DNA-binding protein 0.0062 0.0556 0.0687
Loa Loa (eye worm) major facilitator superfamily transporter 0.003 0.0203 0.0334
Trichomonas vaginalis chromobox protein, putative 0.0068 0.0625 0.1024
Schistosoma mansoni single-minded 0.0053 0.0454 0.0561
Loa Loa (eye worm) hypothetical protein 0.0013 0.0015 0.0024
Trichomonas vaginalis chromodomain helicase DNA binding protein, putative 0.0018 0.007 0.0112
Plasmodium falciparum phd finger protein, putative 0.0028 0.0185 0.0182
Mycobacterium tuberculosis Probable nitrite reductase [NAD(P)H] large subunit [FAD flavoprotein] NirB 0.0092 0.0893 0.1733
Brugia malayi dihydrolipoyl dehydrogenase, mitochondrial precursor, putative 0.0014 0.0024 0.0035
Schistosoma mansoni nAChR subunit (ShAR1-beta-like) 0.0024 0.0141 0.0172
Loa Loa (eye worm) thioredoxin reductase 0.004 0.0317 0.0521
Toxoplasma gondii histone lysine acetyltransferase GCN5-B 0.0046 0.0382 0.0574
Plasmodium falciparum GTP-binding nuclear protein RAN/TC4 0.0023 0.0124 0.0122
Echinococcus multilocularis calcium:calmodulin dependent protein kinase type 0.0066 0.0602 0.0747
Toxoplasma gondii facilitative glucose transporter GT1 0.0214 0.2254 0.3406
Plasmodium vivax calcium-dependent protein kinase 3, putative 0.0066 0.0602 0.06
Schistosoma mansoni protein kinase 0.0066 0.0602 0.0744
Brugia malayi Eukaryotic-type carbonic anhydrase family protein 0.0171 0.1777 0.2918
Echinococcus multilocularis solute carrier family 2 facilitated glucose 0.0214 0.2254 0.2796
Echinococcus granulosus glycine receptor subunit alpha 1 0.0024 0.0141 0.0174
Loa Loa (eye worm) hypothetical protein 0.0039 0.0306 0.0503
Loa Loa (eye worm) hypothetical protein 0.0024 0.0141 0.0231
Schistosoma mansoni carbonic anhydrase-related 0.0171 0.1777 0.2202
Trichomonas vaginalis sugar transporter, putative 0.003 0.0203 0.0331
Schistosoma mansoni histone-lysine n-methyltransferase setb1 0.0062 0.0554 0.0685
Mycobacterium leprae Possible lysyl-tRNA synthetase 2 LysX 0.0048 0.0401 0.2552
Trichomonas vaginalis glucosylceramidase, putative 0.0183 0.1911 0.3138
Trichomonas vaginalis chromodomain helicase DNA binding protein, putative 0.0018 0.007 0.0112
Brugia malayi Neurotransmitter-gated ion-channel ligand binding domain containing protein 0.0024 0.0141 0.0227
Onchocerca volvulus 0.0024 0.0141 0.024
Leishmania major prolyl-tRNA synthetase, putative,bifunctional aminoacyl-tRNA synthetase, putative 0.0075 0.0703 0.1782
Brugia malayi hypothetical protein 0.0039 0.0306 0.05
Trypanosoma brucei DNA polymerase kappa, putative 0.0019 0.0078 0.0192
Mycobacterium ulcerans cytochrome P450 105Q4 Cyp105Q4 0.0039 0.0306 0.05
Echinococcus granulosus carbonic anhydrase 0.0171 0.1777 0.2204
Brugia malayi acetyltransferase, GNAT family protein 0.0157 0.1615 0.2652
Echinococcus multilocularis Sugar transporter ERD6 protein 0.003 0.0203 0.0252
Brugia malayi major facilitator superfamily protein 0.003 0.0203 0.0331
Echinococcus granulosus nAChR subunit 0.0013 0.0015 0.0018
Echinococcus multilocularis calcium dependent protein kinase 0.0061 0.0553 0.0686
Trichomonas vaginalis sugar transporter, putative 0.0066 0.0608 0.0996
Trichomonas vaginalis sugar transporter, putative 0.003 0.0203 0.0331
Mycobacterium ulcerans DNA polymerase IV 0.0019 0.0078 0.0124
Echinococcus granulosus sodium and chloride dependent glycine 0.0017 0.0053 0.0066
Echinococcus multilocularis nicotinic acetylcholine receptor alpha subunit 0.0024 0.0141 0.0174
Plasmodium vivax dihydrolipoyl dehydrogenase, mitochondrial, putative 0.0014 0.0024 0.0021
Trypanosoma cruzi DNA polymerase kappa, putative 0.0019 0.0078 0.0192
Brugia malayi Eukaryotic-type carbonic anhydrase family protein 0.0171 0.1777 0.2918
Echinococcus multilocularis nicotinic acetylcholine receptor subunit alpha 8 0.0024 0.0141 0.0174
Trypanosoma cruzi dihydrolipoamide dehydrogenase, putative 0.0014 0.0024 0.0054
Plasmodium falciparum calcium-dependent protein kinase 4 0.0066 0.0602 0.06
Loa Loa (eye worm) hypothetical protein 0.0074 0.0693 0.1139
Trichomonas vaginalis guanylate cyclase, putative 0.0014 0.002 0.003
Trypanosoma cruzi cytochrome P450, putative 0.0039 0.0306 0.0773
Trichomonas vaginalis conserved hypothetical protein 0.0027 0.0168 0.0273
Loa Loa (eye worm) hypothetical protein 0.0039 0.0306 0.0503
Brugia malayi Importin beta-1 subunit 0.0031 0.0216 0.0351
Mycobacterium tuberculosis Possible cytochrome P450 135A1 Cyp135A1 0.0039 0.0306 0.0592
Trypanosoma cruzi lysyl-tRNA synthetase, putative 0.0048 0.0401 0.1014
Mycobacterium ulcerans short chain dehydrogenase 0.0013 0.0011 0.0015
Toxoplasma gondii calcium-dependent protein kinase CDPK2A 0.0066 0.0602 0.0908
Loa Loa (eye worm) hypothetical protein 0.0088 0.0849 0.1395
Trypanosoma cruzi trypanothione reductase, putative 0.0014 0.0024 0.0054
Trypanosoma brucei THT1 - hexose transporter, putative 0.0066 0.0608 0.1542
Entamoeba histolytica serine/threonine protein kinase, putative 0.0096 0.094 0.2811
Loa Loa (eye worm) eukaryotic-type carbonic anhydrase 0.0171 0.1777 0.292
Plasmodium vivax calcium-dependent protein kinase 1, putative 0.0066 0.0602 0.06
Trichomonas vaginalis fructose-bisphosphate aldolase, putative 0.0311 0.3339 0.5486
Mycobacterium tuberculosis Probable cytochrome P450 138 Cyp138 0.0039 0.0306 0.0592
Trypanosoma brucei dihydrolipoamide dehydrogenase 0.0014 0.0024 0.0054
Toxoplasma gondii aldehyde dehydrogenase 0.0124 0.1257 0.1898
Echinococcus granulosus dihydrolipoamide dehydrogenase 0.0014 0.0024 0.0029
Trichomonas vaginalis Importin beta-1 subunit, putative 0.0025 0.015 0.0243
Trichomonas vaginalis glucosylceramidase, putative 0.0279 0.2981 0.4898
Echinococcus granulosus Transcription factor JmjC domain containing protein 0.0093 0.0905 0.1122
Mycobacterium tuberculosis Probable NADH dehydrogenase Ndh 0.0092 0.0893 0.1733
Trichomonas vaginalis chromobox protein, putative 0.0068 0.0625 0.1024
Echinococcus multilocularis thioredoxin glutathione reductase 0.0041 0.0323 0.0401
Onchocerca volvulus 0.0039 0.0302 0.0547
Trichomonas vaginalis conserved hypothetical protein 0.0014 0.002 0.003
Loa Loa (eye worm) glycyl-tRNA synthetase 0.0012 0.0002 0.0004
Schistosoma mansoni histone-lysine n-methyltransferase suv9 0.0073 0.0678 0.0838
Toxoplasma gondii sugar transporter ST2 0.003 0.0203 0.0304
Leishmania major glucose transporter, lmgt2 0.0066 0.0608 0.1542
Schistosoma mansoni cpg binding protein 0.0033 0.0234 0.0287
Schistosoma mansoni cytochrome P450 0.0039 0.0306 0.0377
Schistosoma mansoni lysyl-tRNA synthetase 0.0048 0.0401 0.0494
Brugia malayi Peroxidasin 0.0039 0.0306 0.05
Loa Loa (eye worm) cytochrome P450 family protein 0.0039 0.0306 0.0503
Trichomonas vaginalis sugar transporter, putative 0.003 0.0203 0.0331
Schistosoma mansoni mixed-lineage leukemia protein mll 0.0019 0.0082 0.0099
Mycobacterium leprae Probable lipase LipE 0.0074 0.0693 0.4425
Mycobacterium ulcerans cytochrome P450 126A3 Cyp126A3 0.0039 0.0306 0.05
Onchocerca volvulus 0.003 0.0203 0.036
Loa Loa (eye worm) GABA receptor subunit 0.0013 0.0015 0.0024
Echinococcus granulosus terminal deoxycytidyl transferase rev1 0.0019 0.0078 0.0096
Echinococcus granulosus lysyl tRNA synthetase 0.0048 0.0401 0.0497
Trichomonas vaginalis CAMK family protein kinase 0.0096 0.094 0.1542
Trypanosoma cruzi trypanothione reductase, putative 0.004 0.0317 0.0801
Leishmania major DNA polymerase kappa, putative 0.0019 0.0078 0.0192
Leishmania major hypothetical protein, conserved 0.0074 0.0693 0.1758
Leishmania major aldehyde dehydrogenase, mitochondrial precursor 0.0124 0.1257 0.3193
Loa Loa (eye worm) transcription factor SMAD2 0.0129 0.1307 0.2148
Loa Loa (eye worm) hypothetical protein 0.0176 0.1835 0.3017
Onchocerca volvulus 0.0024 0.0141 0.024
Trypanosoma cruzi STE/STE11 serine/threonine-protein kinase, putative 0.0018 0.0069 0.0171
Trichomonas vaginalis chromodomain helicase DNA binding protein, putative 0.0018 0.007 0.0112
Brugia malayi Corticotropin releasing factor receptor 2 precursor, putative 0.0054 0.0469 0.0767
Echinococcus multilocularis sodium and chloride dependent glycine 0.0017 0.0053 0.0066
Loa Loa (eye worm) hypothetical protein 0.003 0.0203 0.0334
Schistosoma mansoni peroxidasin 0.0039 0.0306 0.0377
Echinococcus granulosus guanine nucleotide binding protein Gs subunit 0.0136 0.1381 0.1712
Schistosoma mansoni hypothetical protein 0.0171 0.1777 0.2202
Toxoplasma gondii hypothetical protein 0.0017 0.0053 0.0077
Onchocerca volvulus 0.0039 0.0306 0.0555
Plasmodium vivax histone acetyltransferase GCN5, putative 0.0046 0.0382 0.038
Echinococcus granulosus calcium:calmodulin dependent protein kinase type 0.0066 0.0602 0.0747
Trypanosoma brucei DNA polymerase kappa, putative 0.0019 0.0078 0.0192
Toxoplasma gondii histone lysine acetyltransferase GCN5-A 0.0046 0.0382 0.0574
Trichomonas vaginalis sugar transporter, putative 0.003 0.0203 0.0331
Echinococcus multilocularis dihydrolipoamide dehydrogenase 0.0014 0.0024 0.0029
Trichomonas vaginalis chromodomain-helicase-DNA-binding protein, putative 0.0018 0.007 0.0112
Plasmodium vivax amine transporter, putative 0.0017 0.0053 0.0051
Schistosoma mansoni norepinephrine/norepinephrine transporter 0.0017 0.0053 0.0063
Leishmania major lanosterol 14-alpha-demethylase, putative 0.0039 0.0306 0.0773
Toxoplasma gondii histone lysine methyltransferase SET1 0.0065 0.0592 0.0892
Trichomonas vaginalis adenylate cyclase, type VII, putative 0.0014 0.002 0.003
Brugia malayi Neurotransmitter-gated ion-channel ligand binding domain containing protein 0.0024 0.0141 0.0227
Trichomonas vaginalis sugar transporter, putative 0.003 0.0203 0.0331
Echinococcus granulosus General substrate transporter 0.0184 0.1919 0.238
Loa Loa (eye worm) hypothetical protein 0.0037 0.0279 0.0458
Mycobacterium leprae Possible short-chain dehydrogenase EphD 0.0013 0.0011 0.0059
Loa Loa (eye worm) hypothetical protein 0.0039 0.0306 0.0503
Schistosoma mansoni nAChR subunit 0.0024 0.0141 0.0172
Loa Loa (eye worm) jmjC domain-containing protein 0.0059 0.0522 0.0857
Schistosoma mansoni nAChR subunit 0.0024 0.0141 0.0172
Mycobacterium tuberculosis Probable cytochrome P450 130 Cyp130 0.0039 0.0306 0.0592
Loa Loa (eye worm) calcium/calmodulin-dependent protein kinase ID 0.0066 0.0602 0.0989
Trichomonas vaginalis sugar transporter, putative 0.003 0.0203 0.0331
Brugia malayi Cytochrome P450 family protein 0.0136 0.1384 0.2272
Brugia malayi Neurotransmitter-gated ion-channel transmembrane region family protein 0.0013 0.0015 0.0021
Schistosoma mansoni histone-lysine n-methyltransferase setb1 0.0062 0.0554 0.0685
Loa Loa (eye worm) hypothetical protein 0.0039 0.0306 0.0503
Onchocerca volvulus Peroxidasin homolog 0.0039 0.0306 0.0555
Trypanosoma cruzi hexose transporter 0.0066 0.0608 0.1542
Schistosoma mansoni chromodomain helicase DNA binding protein 0.0013 0.0012 0.0012
Trypanosoma cruzi hexose transporter, putative 0.0066 0.0608 0.1542
Giardia lamblia Kinase, PLK 0.0096 0.094 0.2811
Onchocerca volvulus 0.003 0.0203 0.036
Echinococcus granulosus 3 hydroxyacyl coenzyme A dehydrogenase type 2 0.0118 0.118 0.1464
Loa Loa (eye worm) glutaminase 2 0.0557 0.6085 1
Trichomonas vaginalis lysyl-tRNA synthetase, putative 0.0048 0.0401 0.0655
Loa Loa (eye worm) hypoxia-induced factor 1 0.0163 0.1683 0.2766
Trichomonas vaginalis adenylate and guanylate cyclases, putative 0.0014 0.002 0.003
Trypanosoma brucei DNA polymerase kappa, putative 0.0013 0.0013 0.0026
Trichomonas vaginalis sugar transporter, putative 0.003 0.0203 0.0331
Loa Loa (eye worm) hypothetical protein 0.0017 0.0053 0.0087
Leishmania major PAS-domain containing phosphoglycerate kinase, putative 0.0014 0.002 0.0046
Trichomonas vaginalis conserved hypothetical protein 0.0038 0.0292 0.0477
Schistosoma mansoni sodium/chloride dependent neurotransmitter transporter 0.011 0.1091 0.1351
Loa Loa (eye worm) TAR-binding protein 0.0062 0.0556 0.0914
Brugia malayi 3-hydroxyacyl-CoA dehydrogenase type II 0.0118 0.118 0.1937
Onchocerca volvulus Dual oxidase homolog 0.0039 0.0306 0.0555
Onchocerca volvulus 0.0074 0.0693 0.1293
Echinococcus granulosus carbonic anhydrase II 0.0364 0.3932 0.4877
Plasmodium vivax importin-beta 2, putative 0.0031 0.0216 0.0213
Echinococcus multilocularis histone lysine N methyltransferase SETMAR 0.0062 0.0554 0.0687
Schistosoma mansoni hypothetical protein 0.0039 0.0306 0.0377
Loa Loa (eye worm) hypothetical protein 0.011 0.1091 0.1793
Plasmodium falciparum proline--tRNA ligase 0.0075 0.0703 0.07
Schistosoma mansoni sugar transporter 0.003 0.0203 0.025
Schistosoma mansoni cpg binding protein 0.0031 0.0214 0.0263
Trichomonas vaginalis chromobox protein, putative 0.0041 0.0325 0.053
Trichomonas vaginalis conserved hypothetical protein 0.003 0.0203 0.0331
Loa Loa (eye worm) Sodium:neurotransmitter symporter family protein 0.0017 0.0053 0.0087
Loa Loa (eye worm) hypothetical protein 0.0024 0.0141 0.0231
Brugia malayi RNA binding protein 0.0062 0.0556 0.0911
Echinococcus multilocularis neuronal acetylcholine receptor subunit alpha 4 0.0024 0.0141 0.0174
Mycobacterium tuberculosis Probable cytochrome P450 137 Cyp137 0.0039 0.0306 0.0592
Trichomonas vaginalis sugar transporter, putative 0.003 0.0203 0.0331
Echinococcus granulosus nicotinic acetylcholine receptor alpha subunit 0.0024 0.0141 0.0174
Echinococcus multilocularis chromobox protein 1 0.0068 0.0625 0.0775
Trypanosoma brucei unspecified product 0.0013 0.0013 0.0026
Trichomonas vaginalis sugar transporter, putative 0.003 0.0203 0.0331
Plasmodium vivax hypothetical protein, conserved 0.0028 0.0185 0.0182
Echinococcus multilocularis terminal deoxycytidyl transferase rev1 0.0019 0.0078 0.0096
Trypanosoma cruzi dihydrolipoyl dehydrogenase, putative 0.0014 0.0024 0.0054
Loa Loa (eye worm) hypothetical protein 0.0039 0.0306 0.0503
Trypanosoma brucei importin beta-1 subunit, putative 0.0031 0.0216 0.0543
Toxoplasma gondii LsmAD domain-containing protein 0.0053 0.0461 0.0694
Brugia malayi Neurotransmitter-gated ion-channel transmembrane region family protein 0.0024 0.0141 0.0227
Plasmodium vivax CDK-related protein kinase 6, putative 0.0908 1 1
Brugia malayi cytochrome P450 0.0039 0.0306 0.05
Mycobacterium ulcerans glutaminase 0.0557 0.6085 1
Mycobacterium tuberculosis Putative ferredoxin reductase 0.0092 0.0893 0.1733
Trypanosoma cruzi dihydrolipoamide dehydrogenase, putative 0.0014 0.0024 0.0054
Trichomonas vaginalis D-aminoacylase, putative 0.0074 0.0693 0.1136
Loa Loa (eye worm) hypothetical protein 0.0064 0.0584 0.096
Mycobacterium tuberculosis Probable hydrolase 0.0074 0.0693 0.1345
Toxoplasma gondii thioredoxin reductase 0.004 0.0317 0.0476
Schistosoma mansoni nicotinic acetylcholine receptor alpha 0.0013 0.0015 0.0016
Trichomonas vaginalis D-aminoacylase, putative 0.0074 0.0693 0.1136
Brugia malayi Bifunctional aminoacyl-tRNA synthetase 0.0064 0.0584 0.0956
Schistosoma mansoni sodium/chloride dependent transporter 0.0017 0.0053 0.0063
Plasmodium vivax glutathione reductase, putative 0.004 0.0317 0.0315
Brugia malayi Neurotransmitter-gated ion-channel transmembrane region family protein 0.0024 0.0141 0.0227
Schistosoma mansoni terminal deoxycytidyl transferase 0.0019 0.0078 0.0094
Leishmania major DNA polymerase kappa, putative,DNA polymerase IV, putative 0.0019 0.0078 0.0192
Echinococcus granulosus diuretic hormone 44 receptor GPRdih2 0.0017 0.0058 0.0072
Echinococcus granulosus peregrin 0.0032 0.0227 0.0282
Brugia malayi CXXC zinc finger family protein 0.0031 0.0214 0.0348
Loa Loa (eye worm) RNA binding protein 0.0062 0.0556 0.0914
Echinococcus granulosus sodium:chloride dependent neurotransmitter 0.011 0.1091 0.1353
Loa Loa (eye worm) hypothetical protein 0.0024 0.0141 0.0231
Loa Loa (eye worm) hypothetical protein 0.003 0.0203 0.0334
Brugia malayi ImpB/MucB/SamB family protein 0.0019 0.0078 0.0124
Loa Loa (eye worm) threonyl-tRNA synthetase 0.0012 0.0002 0.0004
Trypanosoma brucei glucose transporter 2A 0.0066 0.0608 0.1542
Wolbachia endosymbiont of Brugia malayi dihydrolipoamide dehydrogenase E3 component 0.0014 0.0024 0.1064
Trichomonas vaginalis sugar transporter, putative 0.003 0.0203 0.0331
Mycobacterium tuberculosis Probable cytochrome P450 136 Cyp136 0.0039 0.0306 0.0592
Trypanosoma cruzi dihydrolipoyl dehydrogenase, putative 0.0014 0.0024 0.0054
Loa Loa (eye worm) norepinephrine transporter 0.0017 0.0053 0.0087
Loa Loa (eye worm) hypothetical protein 0.011 0.1091 0.1793
Echinococcus multilocularis solute carrier family 22 0.003 0.0203 0.0252
Trichomonas vaginalis sugar transporter, putative 0.003 0.0203 0.0331
Loa Loa (eye worm) hypothetical protein 0.0013 0.0015 0.0024
Loa Loa (eye worm) hypothetical protein 0.003 0.0203 0.0334
Toxoplasma gondii PHD-finger domain-containing protein 0.0028 0.0185 0.0276
Trypanosoma cruzi prolyl-tRNA synthetase, putative 0.0075 0.0703 0.1782
Leishmania major glucose transporter, lmgt3 0.0066 0.0608 0.1542
Trichomonas vaginalis conserved hypothetical protein 0.0015 0.0034 0.0052
Trichomonas vaginalis glucosylceramidase, putative 0.0183 0.1911 0.3138
Trypanosoma cruzi hexose transporter, putative 0.0036 0.0272 0.0688
Trypanosoma cruzi prolyl-tRNA synthetase, putative 0.0075 0.0703 0.1782
Giardia lamblia Hexose transporter 0.003 0.0203 0.0603
Trypanosoma cruzi sugar transporter, putative 0.003 0.0203 0.0512
Schistosoma mansoni sodium/chloride dependent neurotransmitter transporter 0.011 0.1091 0.1351
Schistosoma mansoni nuclear transcription factor X-box binding 1 (nfx1) 0.003 0.0203 0.025
Schistosoma mansoni Cys-loop ligand gated ion channel subunit 0.0024 0.0141 0.0172
Entamoeba histolytica hypothetical protein 0.0048 0.0401 0.1194
Echinococcus granulosus peroxidasin 0.0039 0.0306 0.038
Echinococcus multilocularis glycine receptor subunit alpha 1 0.0024 0.0141 0.0174
Leishmania major prolyl-tRNA synthetase, putative,bifunctional aminoacyl-tRNA synthetase, putative 0.0075 0.0703 0.1782
Echinococcus granulosus solute carrier family 2 facilitated glucose 0.0214 0.2254 0.2796
Mycobacterium tuberculosis Possible cytochrome P450 126 Cyp126 0.0039 0.0306 0.0592
Loa Loa (eye worm) hypothetical protein 0.0039 0.0306 0.0503
Loa Loa (eye worm) hypothetical protein 0.0048 0.0401 0.0658
Schistosoma mansoni Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) 0.0136 0.1381 0.171
Brugia malayi Animal haem peroxidase family protein 0.0039 0.0306 0.05
Schistosoma mansoni glucose transport protein 0.0214 0.2254 0.2794
Brugia malayi Hypothetical 52.5 kDa protein ZK945.1 in chromosome II, putative 0.0074 0.0693 0.1136
Brugia malayi Sodium:neurotransmitter symporter family protein 0.0017 0.0053 0.0084
Mycobacterium ulcerans cytochrome P450 51B1 Cyp51B1 0.0039 0.0306 0.05
Echinococcus multilocularis guanine nucleotide binding protein G(s) subunit 0.0136 0.1381 0.1712
Echinococcus granulosus glycine receptor subunit beta 0.0024 0.0141 0.0174
Echinococcus granulosus importin subunit beta 1 0.0031 0.0216 0.0267
Loa Loa (eye worm) hypothetical protein 0.0013 0.0015 0.0024
Plasmodium falciparum hexose transporter 0.0214 0.2254 0.2253
Brugia malayi Neurotransmitter-gated ion-channel ligand binding domain containing protein 0.0024 0.0141 0.0227
Echinococcus granulosus cadherin EGF LAG seven pass G type receptor 0.0017 0.0058 0.0072
Schistosoma mansoni sodium/chloride dependent transporter 0.0021 0.0102 0.0124
Schistosoma mansoni glutaminase 0.0557 0.6085 0.7546
Echinococcus multilocularis solute carrier family 22 0.003 0.0203 0.0252
Trichomonas vaginalis adenylate and guanylate cyclases, putative 0.0014 0.002 0.003
Mycobacterium tuberculosis Probable cytochrome P450 123 Cyp123 0.0039 0.0306 0.0592
Entamoeba histolytica fructose-1,6-bisphosphate aldolase, putative 0.0311 0.3339 1
Mycobacterium tuberculosis Probable lipase LipD 0.0074 0.0693 0.1345
Loa Loa (eye worm) hypothetical protein 0.003 0.0203 0.0334
Schistosoma mansoni glutamyl-tRNA synthetase cytoplasmic (glutamate--tRNA ligase) (glurs) 0.0064 0.0584 0.0722
Plasmodium falciparum mitogen-activated protein kinase 2 0.0346 0.3728 0.3726
Brugia malayi glutathione reductase 0.004 0.0317 0.0518
Loa Loa (eye worm) hypothetical protein 0.0171 0.1777 0.292
Loa Loa (eye worm) hypothetical protein 0.0024 0.0141 0.0231
Schistosoma mansoni carbonic anhydrase II (carbonate dehydratase II) 0.0364 0.3932 0.4875
Plasmodium vivax sugar transporter, putative 0.003 0.0203 0.0201
Loa Loa (eye worm) hypothetical protein 0.003 0.0203 0.0334
Plasmodium falciparum carbonic anhydrase 0.0171 0.1777 0.1775
Echinococcus multilocularis tar DNA binding protein 0.0062 0.0556 0.069
Schistosoma mansoni hypothetical protein 0.0024 0.0134 0.0164
Echinococcus granulosus solute carrier family 22 0.003 0.0203 0.0252
Trichomonas vaginalis sugar transporter, putative 0.003 0.0203 0.0331
Echinococcus granulosus calcium:calmodulin dependent protein kinase type 0.0066 0.0602 0.0747
Schistosoma mansoni sodium-dependent neurotransmitter transporter 0.0017 0.0053 0.0063
Trichomonas vaginalis glucosylceramidase, putative 0.0183 0.1911 0.3138
Echinococcus multilocularis calcium:calmodulin dependent protein kinase type 0.0066 0.0602 0.0747
Trypanosoma brucei DNA polymerase kappa, putative 0.0019 0.0078 0.0192
Schistosoma mansoni carbonic anhydrase II (carbonate dehydratase II) 0.0364 0.3932 0.4875
Plasmodium vivax hypothetical protein, conserved 0.0074 0.0693 0.0691
Leishmania major dihydrolipoamide dehydrogenase, putative 0.0014 0.0024 0.0054
Trypanosoma cruzi polo-like protein kinase, putative 0.0096 0.094 0.2386
Trichomonas vaginalis glucose transporter, putative 0.003 0.0203 0.0331
Chlamydia trachomatis lysine--tRNA ligase 0.0048 0.0401 1
Echinococcus granulosus calcium:calmodulin dependent protein kinase type 1 0.0066 0.0602 0.0747
Trypanosoma brucei dihydrolipoyl dehydrogenase 0.0014 0.0024 0.0054
Schistosoma mansoni serine/threonine protein kinase 0.0066 0.0602 0.0744
Echinococcus granulosus Aryl hydrocarbon receptor nuclear 0.0014 0.002 0.0025
Plasmodium falciparum major facilitator superfamily domain-containing protein, putative 0.003 0.0203 0.0201
Trypanosoma brucei glucose transporter, putative 0.0066 0.0608 0.1542
Mycobacterium tuberculosis Probable short-chain type dehydrogenase/reductase 0.0118 0.118 0.2293
Echinococcus granulosus solute carrier family 22 0.003 0.0203 0.0252
Entamoeba histolytica fructose-1,6-bisphosphate aldolase, putative 0.0311 0.3339 1
Brugia malayi bHLH-PAS transcription factor 0.0039 0.0302 0.0493
Giardia lamblia Prolyl-tRNA synthetase 0.0064 0.0584 0.1743
Trichomonas vaginalis prolyl-tRNA synthetase, putative 0.0064 0.0584 0.0956
Echinococcus multilocularis nicotinic acetylcholine receptor beta 1 subunit 0.0024 0.0141 0.0174
Trichomonas vaginalis chromodomain helicase DNA binding protein, putative 0.0018 0.007 0.0112
Echinococcus granulosus cytochrome P450 2K1 0.0039 0.0306 0.038
Trichomonas vaginalis esterase, putative 0.0074 0.0693 0.1136
Trichomonas vaginalis conserved hypothetical protein 0.0014 0.002 0.003
Loa Loa (eye worm) hypothetical protein 0.0039 0.0306 0.0503
Mycobacterium tuberculosis NAD(P)H quinone reductase LpdA 0.0102 0.1007 0.1956
Schistosoma mansoni mixed-lineage leukemia protein mll 0.0068 0.0627 0.0775
Trypanosoma brucei cytochrome P450, putative 0.0039 0.0306 0.0773
Echinococcus granulosus solute carrier family 22 0.003 0.0203 0.0252
Trichomonas vaginalis sugar transporter, putative 0.003 0.0203 0.0331
Plasmodium vivax GTP-binding nuclear protein RAN/TC4, putative 0.0023 0.0124 0.0122
Brugia malayi O-Glycosyl hydrolase family 30 protein 0.0279 0.2981 0.4898
Leishmania major trypanothione reductase 0.004 0.0317 0.0801
Toxoplasma gondii ABC1 family protein 0.0074 0.0693 0.1045
Trypanosoma brucei DNA polymerase IV, putative 0.0019 0.0078 0.0192
Trypanosoma brucei DNA polymerase kappa, putative 0.0019 0.0078 0.0192
Entamoeba histolytica hypothetical protein 0.0025 0.015 0.0442
Trypanosoma cruzi DNA polymerase kappa, putative 0.0019 0.0078 0.0192
Schistosoma mansoni sugar transporter 0.003 0.0203 0.025
Mycobacterium ulcerans DNA polymerase IV 0.0019 0.0078 0.0124
Loa Loa (eye worm) pre-SET domain-containing protein family protein 0.0425 0.4607 0.7572
Trichomonas vaginalis fructose-bisphosphate aldolase, putative 0.0311 0.3339 0.5486
Mycobacterium tuberculosis Cytochrome P450 121 Cyp121 0.0039 0.0306 0.0592
Trichomonas vaginalis conserved hypothetical protein 0.0066 0.0608 0.0996
Mycobacterium ulcerans short-chain type dehydrogenase/reductase 0.0118 0.118 0.1937
Echinococcus multilocularis 3 hydroxyacyl coenzyme A dehydrogenase type 2 0.0118 0.118 0.1464
Trypanosoma cruzi hypothetical protein, conserved 0.0074 0.0693 0.1758
Trichomonas vaginalis importin beta-1, putative 0.0025 0.015 0.0243
Chlamydia trachomatis two component regulatory system sensor histidine kinase 0.0014 0.002 0.0456
Echinococcus multilocularis carbonic anhydrase 0.0171 0.1777 0.2204
Schistosoma mansoni hypothetical protein 0.0214 0.2254 0.2794
Entamoeba histolytica protein kinase, putative 0.0066 0.0602 0.1798
Loa Loa (eye worm) nucleolar RNA-associated protein alpha 0.0333 0.3579 0.5882
Schistosoma mansoni Cys-loop ligand gated ion channel subunit 0.0013 0.0015 0.0016
Trichomonas vaginalis soluble guanylate cyclase gcy, putative 0.0014 0.002 0.003
Toxoplasma gondii Sodium:neurotransmitter symporter family protein 0.0017 0.0053 0.0077
Loa Loa (eye worm) eukaryotic-type carbonic anhydrase 0.0364 0.3932 0.6462
Brugia malayi Hypothetical glycine receptor like protein T20B12.9 in chromosome III 0.0013 0.0015 0.0021
Schistosoma mansoni protein kinase 0.0066 0.0602 0.0744
Loa Loa (eye worm) glutathione reductase 0.004 0.0317 0.0521
Plasmodium falciparum glutathione reductase 0.0014 0.0024 0.0021
Loa Loa (eye worm) animal heme peroxidase 0.0039 0.0306 0.0503
Trypanosoma brucei DNA polymerase kappa, putative 0.0019 0.0078 0.0192
Mycobacterium leprae Probable fructose bisphosphate aldolase Fba 0.0152 0.1563 1
Giardia lamblia PHD finger protein 15 0.0028 0.0185 0.0546
Trichomonas vaginalis CAMK family protein kinase 0.0066 0.0602 0.0986
Trypanosoma cruzi GTP-binding nuclear protein rtb2, putative 0.0023 0.0124 0.0309
Loa Loa (eye worm) hypothetical protein 0.0039 0.0306 0.0503
Brugia malayi Eukaryotic-type carbonic anhydrase family protein 0.0171 0.1777 0.2918
Mycobacterium ulcerans fusion of enoyl-CoA hydratase, EchA21 and lipase, LipE 0.0074 0.0693 0.1136
Brugia malayi Sugar transporter family protein 0.0214 0.2254 0.3703
Trypanosoma brucei glucose transporter, putative 0.0066 0.0608 0.1542
Echinococcus multilocularis glycyl tRNA synthetase 0.0012 0.0002 0.0003
Loa Loa (eye worm) hypothetical protein 0.0074 0.0693 0.1139
Schistosoma mansoni sodium/chloride dependent neurotransmitter transporter 0.011 0.1091 0.1351
Trichomonas vaginalis set domain proteins, putative 0.0483 0.5261 0.8646
Echinococcus multilocularis solute carrier family 2, facilitated glucose 0.0214 0.2254 0.2796
Plasmodium vivax ataxin-2 like protein, putative 0.0053 0.0461 0.0459
Echinococcus multilocularis Ataxin 2, N terminal,domain containing protein 0.0024 0.0134 0.0166
Brugia malayi Calcium/calmodulin-dependent protein kinase type II alpha chain 0.0066 0.0602 0.0986
Mycobacterium leprae Conserved hypothetical protein 0.0039 0.0306 0.1946
Loa Loa (eye worm) PHD-finger family protein 0.0028 0.0185 0.0303
Trypanosoma cruzi Lanosterol 14-alpha demethylase 0.0039 0.0306 0.0773
Echinococcus multilocularis Transcription factor, JmjC domain containing protein 0.0093 0.0905 0.1122
Brugia malayi Neurotransmitter-gated ion-channel transmembrane region family protein 0.0024 0.0141 0.0227
Leishmania major protein kinase, putative 0.0066 0.0602 0.1526
Brugia malayi CHD4 protein 0.0013 0.0012 0.0015
Onchocerca volvulus Heterochromatin protein 1 homolog 0.0041 0.0325 0.059
Schistosoma mansoni carbonic anhydrase-related 0.0171 0.1777 0.2202
Brugia malayi Major Facilitator Superfamily protein 0.003 0.0203 0.0331
Loa Loa (eye worm) hypothetical protein 0.0013 0.0015 0.0024
Schistosoma mansoni nAChR subunit 0.0024 0.0141 0.0172
Brugia malayi Cytochrome P450 family protein 0.0039 0.0306 0.05
Trypanosoma brucei THT1 - hexose transporter, putative 0.0066 0.0608 0.1542
Plasmodium vivax calcium-dependent protein kinase, putative 0.0066 0.0602 0.06
Echinococcus multilocularis lysyl tRNA synthetase 0.0048 0.0401 0.0497
Mycobacterium tuberculosis Possible short-chain dehydrogenase EphD 0.0013 0.0011 0.0018
Mycobacterium ulcerans fusion protein of transposase for IS2606 and sialic acid-transport integral membrane protein NanT 0.003 0.0203 0.0331
Mycobacterium tuberculosis Probable conserved lipoprotein 0.0074 0.0693 0.1345
Trichomonas vaginalis conserved hypothetical protein 0.003 0.0203 0.0331
Loa Loa (eye worm) hypothetical protein 0.0019 0.0078 0.0128
Plasmodium falciparum importin beta, putative 0.0031 0.0216 0.0213
Schistosoma mansoni tar DNA-binding protein 0.0062 0.0556 0.0687
Plasmodium vivax mitogen-activated protein kinase 2, putative 0.0346 0.3728 0.3726
Loa Loa (eye worm) hypothetical protein 0.0039 0.0306 0.0503
Trichomonas vaginalis sugar transporter, putative 0.003 0.0203 0.0331
Loa Loa (eye worm) beta-lactamase 0.0074 0.0693 0.1139
Echinococcus granulosus microtubule associated protein 2 0.0734 0.8063 1
Mycobacterium ulcerans sugar-transport integral membrane protein SugI 0.003 0.0203 0.0331
Loa Loa (eye worm) hypothetical protein 0.0013 0.0015 0.0024
Mycobacterium ulcerans cytochrome P450 187A5 Cyp187A5 0.0039 0.0306 0.05
Trypanosoma brucei glucose transporter, putative 0.0066 0.0608 0.1542
Wolbachia endosymbiont of Brugia malayi major facilitator superfamily permease 0.003 0.0203 1
Onchocerca volvulus Alhambra homolog 0.0028 0.0185 0.0324
Onchocerca volvulus Putative transporter 0.003 0.0203 0.036
Loa Loa (eye worm) 3-hydroxyacyl-CoA dehydrogenase type II 0.011 0.1092 0.1794
Mycobacterium ulcerans cytochrome P450 136A2 Cyp136A2 0.0039 0.0306 0.05
Brugia malayi Blistered cuticle protein 3 0.0039 0.0306 0.05
Echinococcus granulosus solute carrier family 22 0.003 0.0203 0.0252
Mycobacterium ulcerans aldehyde dehydrogenase 0.0124 0.1257 0.2063
Loa Loa (eye worm) acetyltransferase 0.0157 0.1615 0.2655
Loa Loa (eye worm) nicotinic acetylcholine receptor non-alpha subunit 0.0024 0.0141 0.0231
Brugia malayi MH2 domain containing protein 0.0129 0.1307 0.2146
Echinococcus granulosus dna polymerase kappa 0.0019 0.0078 0.0096
Onchocerca volvulus 0.003 0.0203 0.036
Trichomonas vaginalis chromodomain-helicase-DNA-binding protein, putative 0.0018 0.007 0.0112
Echinococcus multilocularis histone lysine methyltransferase setb histone lysine methyltransferase eggless 0.0062 0.0554 0.0687
Brugia malayi Neurotransmitter-gated ion-channel ligand binding domain containing protein 0.0024 0.0141 0.0227
Brugia malayi Putative carbonic anhydrase 5 precursor 0.0364 0.3932 0.6461
Trichomonas vaginalis sugar transporter, putative 0.003 0.0203 0.0331
Loa Loa (eye worm) bifunctional aminoacyl-tRNA synthetase 0.0026 0.0162 0.0266
Trypanosoma brucei glucose transporter, putative 0.0066 0.0608 0.1542
Echinococcus granulosus aldehyde dehydrogenase mitochondrial 0.0124 0.1257 0.1559
Trichomonas vaginalis conserved hypothetical protein 0.0038 0.0292 0.0477
Loa Loa (eye worm) acetylcholine receptor alpha subunit 0.0024 0.0141 0.0231
Leishmania major carbonic anhydrase-like protein 0.0364 0.3932 1
Brugia malayi serine/threonine-protein kinase plk-2 0.0096 0.094 0.1542
Mycobacterium ulcerans cytochrome P450 187A4 Cyp187A4 0.0039 0.0306 0.05
Echinococcus granulosus nicotinic acetylcholine receptor beta 1 subunit 0.0024 0.0141 0.0174
Trypanosoma brucei DNA polymerase IV, putative 0.0019 0.0078 0.0192
Toxoplasma gondii Sodium:neurotransmitter symporter family protein 0.0017 0.0053 0.0077
Leishmania major glucose transporter/membrane transporter D2, putative 0.0066 0.0608 0.1542
Trypanosoma brucei DNA polymerase kappa, putative 0.0019 0.0078 0.0192
Treponema pallidum NADH oxidase 0.0014 0.0024 0.0064
Schistosoma mansoni Cys-loop ligand gated ion channel subunit 0.0024 0.0141 0.0172
Brugia malayi Neurotransmitter-gated ion-channel transmembrane region family protein 0.0013 0.0015 0.0021
Onchocerca volvulus Glucosylceramidase homolog 0.0183 0.1911 0.3614
Toxoplasma gondii HEAT repeat-containing protein 0.0031 0.0216 0.0323
Loa Loa (eye worm) hypothetical protein 0.0054 0.0469 0.0771
Brugia malayi acetylcholine receptor alpha subunit precursor, putative 0.0024 0.0141 0.0227
Plasmodium falciparum calcium-dependent protein kinase 5 0.0066 0.0602 0.06
Trichomonas vaginalis chromodomain helicase DNA binding protein, putative 0.0014 0.0028 0.0043
Onchocerca volvulus Chorion peroxidase homolog 0.0039 0.0306 0.0555
Echinococcus multilocularis Threonyl tRNA synthetase, C 0.0012 0.0002 0.0003
Schistosoma mansoni hypothetical protein 0.0333 0.3579 0.4437
Onchocerca volvulus 0.0483 0.5261 1
Echinococcus granulosus dna polymerase eta 0.0019 0.0078 0.0096
Trichomonas vaginalis sugar transporter, putative 0.0066 0.0608 0.0996
Chlamydia trachomatis dihydrolipoyl dehydrogenase 0.0014 0.0024 0.0537
Leishmania major hypothetical protein, conserved 0.003 0.0203 0.0512
Brugia malayi hypothetical protein 0.003 0.0203 0.0331
Loa Loa (eye worm) hypothetical protein 0.0017 0.0053 0.0087
Trypanosoma brucei DNA polymerase kappa, putative 0.0019 0.0078 0.0192
Toxoplasma gondii PHD-finger domain-containing protein 0.0028 0.0185 0.0276
Loa Loa (eye worm) hypothetical protein 0.0052 0.045 0.0739
Brugia malayi calcium-independent alpha-latrotoxin receptor 2, putative 0.0017 0.0058 0.0092
Echinococcus multilocularis glycine receptor subunit beta 0.0024 0.0141 0.0174
Trypanosoma cruzi dihydrolipoamide dehydrogenase, putative 0.0014 0.0024 0.0054
Plasmodium vivax thioredoxin reductase, putative 0.004 0.0317 0.0315
Brugia malayi Pre-SET motif family protein 0.0062 0.0554 0.0908
Loa Loa (eye worm) animal heme peroxidase 0.0039 0.0306 0.0503
Entamoeba histolytica deoxycytidyl transferase, putative 0.0019 0.0078 0.0226
Mycobacterium tuberculosis Probable epoxide hydrolase EphA (epoxide hydratase) (arene-oxide hydratase) 0.018 0.1874 0.3643
Schistosoma mansoni nAChR subunit 0.0024 0.0141 0.0172
Loa Loa (eye worm) CXXC zinc finger family protein 0.0031 0.0214 0.0352
Brugia malayi nicotinic acetylcholine receptor beta-1 chain precursor 0.0024 0.0141 0.0227
Loa Loa (eye worm) hypothetical protein 0.0062 0.0554 0.0911
Trichomonas vaginalis penicillin-binding protein, putative 0.0074 0.0693 0.1136
Plasmodium vivax calcium-dependent protein kinase 4, putative 0.0066 0.0602 0.06
Toxoplasma gondii calcium-dependent protein kinase CDPK2B 0.0066 0.0602 0.0908
Trypanosoma brucei DNA polymerase kappa, putative 0.0019 0.0078 0.0192
Mycobacterium tuberculosis Probable lipase LipE 0.0074 0.0693 0.1345
Leishmania major DNA polymerase eta, putative 0.0019 0.0078 0.0192
Trichomonas vaginalis sugar transporter, putative 0.003 0.0203 0.0331
Echinococcus granulosus beta LACTamase domain containing family member 0.0074 0.0693 0.0859
Trichomonas vaginalis sugar transporter, putative 0.003 0.0203 0.0331
Trichomonas vaginalis glucosylceramidase, putative 0.0279 0.2981 0.4898
Trypanosoma cruzi DNA polymerase kappa, putative 0.0019 0.0078 0.0192
Loa Loa (eye worm) hypothetical protein 0.0017 0.0053 0.0087
Trypanosoma brucei Lanosterol 14-alpha demethylase 0.0039 0.0306 0.0773
Echinococcus granulosus uncharacterized sodium dependent transporter 0.0017 0.0053 0.0066
Trypanosoma brucei unspecified product 0.0019 0.0078 0.0192
Loa Loa (eye worm) hypothetical protein 0.003 0.0203 0.0334
Entamoeba histolytica Acid sphingomyelinase-like phosphodiesterase, putative 0.0088 0.0849 0.2537
Onchocerca volvulus 0.0074 0.0693 0.1293
Schistosoma mansoni hypothetical protein 0.0017 0.0058 0.0069
Loa Loa (eye worm) ligand-Gated ion Channel family member 0.0024 0.0141 0.0231
Loa Loa (eye worm) hypothetical protein 0.0012 0.0002 0.0004
Onchocerca volvulus 0.0039 0.0306 0.0555
Echinococcus granulosus Threonyl tRNA synthetase C 0.0012 0.0002 0.0003
Mycobacterium ulcerans sugar transporter 0.003 0.0203 0.0331
Brugia malayi Neurotransmitter-gated ion-channel ligand binding domain containing protein 0.0024 0.0141 0.0227
Giardia lamblia Sugar-proton symporter 0.003 0.0203 0.0603
Loa Loa (eye worm) hypothetical protein 0.0013 0.0015 0.0024
Wolbachia endosymbiont of Brugia malayi dihydrolipoamide dehydrogenase E3 component 0.0014 0.0024 0.1064
Trichomonas vaginalis fructose-bisphosphate aldolase, putative 0.0311 0.3339 0.5486
Schistosoma mansoni nAChR subunit 0.0024 0.0141 0.0172
Brugia malayi hypothetical protein 0.0017 0.0053 0.0084
Schistosoma mansoni tar DNA-binding protein 0.0062 0.0556 0.0687
Entamoeba histolytica prolyl-tRNA synthetase, putative 0.0064 0.0584 0.1743
Trichomonas vaginalis conserved hypothetical protein 0.003 0.0203 0.0331
Onchocerca volvulus Serine\/threonine kinase homolog 0.0096 0.094 0.1764
Loa Loa (eye worm) hypothetical protein 0.0171 0.1777 0.292
Trichomonas vaginalis glucosylceramidase, putative 0.0183 0.1911 0.3138
Loa Loa (eye worm) hypothetical protein 0.0171 0.1777 0.292
Leishmania major hypothetical protein, conserved 0.0053 0.0461 0.1168
Trypanosoma cruzi hexose transporter, putative 0.0066 0.0608 0.1542
Trypanosoma cruzi dihydrolipoamide dehydrogenase, putative 0.0014 0.0024 0.0054
Mycobacterium ulcerans cytochrome P450 140A5 Cyp140A5 0.0039 0.0306 0.05
Plasmodium falciparum histone acetyltransferase GCN5 0.0042 0.0339 0.0337
Onchocerca volvulus 0.0014 0.002 0.0011
Trypanosoma brucei dihydrolipoamide dehydrogenase 0.0014 0.0024 0.0054
Echinococcus granulosus PHD finger protein rhinoceros 0.0028 0.0185 0.0229
Brugia malayi Bromodomain containing protein 0.0032 0.0227 0.037
Plasmodium falciparum thioredoxin reductase 0.0014 0.0024 0.0021
Brugia malayi SET domain containing protein 0.0014 0.0024 0.0036
Loa Loa (eye worm) Sodium:neurotransmitter symporter family protein 0.0017 0.0053 0.0087
Trichomonas vaginalis sugar transporter, putative 0.003 0.0203 0.0331
Loa Loa (eye worm) hypothetical protein 0.0038 0.0292 0.048
Trypanosoma brucei DNA polymerase kappa, putative 0.0013 0.0013 0.0026
Trichomonas vaginalis CAMK family protein kinase 0.005 0.0422 0.069
Echinococcus granulosus carbonic anhydrase 0.0171 0.1777 0.2204
Schistosoma mansoni jumonji/arid domain-containing protein 0.0036 0.0271 0.0333
Plasmodium falciparum calcium-dependent protein kinase 1 0.0066 0.0602 0.06
Schistosoma mansoni hypothetical protein 0.0028 0.0185 0.0226
Trichomonas vaginalis CAMK family protein kinase 0.0096 0.094 0.1542
Trichomonas vaginalis glucosylceramidase, putative 0.0183 0.1911 0.3138
Trichomonas vaginalis glucosylceramidase, putative 0.0193 0.2021 0.3319
Brugia malayi Latrophilin receptor protein 2 0.0017 0.0058 0.0092
Onchocerca volvulus 0.003 0.0203 0.036
Loa Loa (eye worm) hypothetical protein 0.0024 0.0141 0.0231
Giardia lamblia DINP protein human, muc B family 0.0019 0.0078 0.0226
Mycobacterium tuberculosis Probable cytochrome P450 139 Cyp139 0.0039 0.0306 0.0592
Brugia malayi hypothetical protein 0.0034 0.0251 0.0409
Trichomonas vaginalis glutathione reductase, putative 0.0014 0.0024 0.0035
Echinococcus multilocularis carbonic anhydrase 0.0171 0.1777 0.2204
Plasmodium vivax hexose transporter 0.0214 0.2254 0.2253
Mycobacterium ulcerans cytochrome P450 142A3 Cyp142A3 0.0039 0.0306 0.05
Trichomonas vaginalis DNA polymerase eta, putative 0.0019 0.0078 0.0124
Echinococcus granulosus chromodomain helicase DNA binding protein 4 0.0013 0.0012 0.0014
Entamoeba histolytica protein kinase, putative 0.0066 0.0602 0.1798
Trichomonas vaginalis glucosylceramidase, putative 0.0279 0.2981 0.4898
Mycobacterium ulcerans putative regulatory protein 0.0039 0.0302 0.0493
Echinococcus granulosus calcium dependent protein kinase 0.0061 0.0553 0.0686
Trypanosoma brucei PAB1-binding protein , putative 0.0053 0.0461 0.1168
Plasmodium falciparum ataxin-2 like protein, putative 0.0053 0.0461 0.0459
Echinococcus multilocularis GPCR, family 2 0.0017 0.0058 0.0072
Toxoplasma gondii hypothetical protein 0.0017 0.0053 0.0077
Trypanosoma cruzi PAB1-binding protein , putative 0.0053 0.0461 0.1168
Onchocerca volvulus 0.0024 0.0141 0.024
Loa Loa (eye worm) hypothetical protein 0.0017 0.0058 0.0095
Echinococcus granulosus thioredoxin glutathione reductase 0.0041 0.0323 0.0401
Loa Loa (eye worm) carbonic anhydrase 3 0.0364 0.3932 0.6462
Trypanosoma cruzi hypothetical protein, conserved 0.0074 0.0693 0.1758
Loa Loa (eye worm) hypothetical protein 0.0074 0.0693 0.1139
Echinococcus multilocularis peroxidasin 0.0039 0.0306 0.038
Loa Loa (eye worm) hypothetical protein 0.0028 0.0185 0.0303
Echinococcus granulosus glutamyl tRNA synthetase cytoplasmic 0.0064 0.0584 0.0724
Schistosoma mansoni hypothetical protein 0.0524 0.5709 0.708
Onchocerca volvulus Putative nachr subunit 0.0024 0.0141 0.024
Echinococcus granulosus neuronal acetylcholine receptor subunit alpha 4 0.0024 0.0141 0.0174
Trichomonas vaginalis glucose transporter, putative 0.0066 0.0608 0.0996
Echinococcus granulosus snurportin 1 0.0333 0.3579 0.4439
Trichomonas vaginalis glutaminase, putative 0.0557 0.6085 1
Schistosoma mansoni hypothetical protein 0.0442 0.4799 0.5951
Mycobacterium tuberculosis Possible cytochrome P450 135B1 Cyp135B1 0.0039 0.0306 0.0592
Trichomonas vaginalis adenylate and guanylate cyclases, putative 0.0014 0.002 0.003
Echinococcus granulosus GTP binding nuclear protein Ran 0.0023 0.0124 0.0153
Loa Loa (eye worm) CYP4Cod1 0.0039 0.0306 0.0503
Trypanosoma cruzi glucose transporter, putative 0.003 0.0203 0.0512
Mycobacterium tuberculosis Probable conserved integral membrane transport protein 0.003 0.0203 0.0392
Loa Loa (eye worm) hypothetical protein 0.0053 0.0461 0.0758
Echinococcus granulosus 5'partial|histone lysine N methyltransferase SETDB2 0.0059 0.0522 0.0647
Mycobacterium ulcerans cytochrome p450 150 cyp150 0.0039 0.0306 0.05
Loa Loa (eye worm) hypothetical protein 0.0013 0.0015 0.0024
Trypanosoma brucei calcium/calmodulin-dependent protein kinase, putative 0.0066 0.0602 0.1526
Echinococcus multilocularis calcium:calmodulin dependent protein kinase type 0.0066 0.0602 0.0747
Trypanosoma cruzi polo-like protein kinase, putative 0.0096 0.094 0.2386
Loa Loa (eye worm) RNA recognition domain-containing protein domain-containing protein 0.0062 0.0556 0.0914
Mycobacterium tuberculosis Possible penicillin-binding protein 0.0472 0.5139 1
Echinococcus multilocularis dnaJ subfamily B 0.0442 0.4799 0.5952
Plasmodium falciparum calcium-dependent protein kinase 3 0.0066 0.0602 0.06
Schistosoma mansoni hypothetical protein 0.0017 0.0058 0.0069
Mycobacterium ulcerans cytochrome P450 191A3 Cyp191A3 0.0039 0.0306 0.05
Mycobacterium ulcerans beta-lactamase 0.0074 0.0693 0.1136
Brugia malayi lysyl-tRNA synthetase 0.0048 0.0401 0.0655
Loa Loa (eye worm) hypothetical protein 0.0024 0.0141 0.0231
Leishmania major 2-oxoglutarate dehydrogenase, e3 component, lipoamidedehydrogenase-like protein 0.0014 0.0024 0.0054
Mycobacterium tuberculosis Probable oxidoreductase 0.0102 0.1007 0.1956
Echinococcus multilocularis glycine receptor subunit beta 0.0024 0.0141 0.0174
Onchocerca volvulus 0.0031 0.0214 0.038
Echinococcus multilocularis glycine receptor subunit alpha 1 0.0024 0.0141 0.0174
Mycobacterium tuberculosis Probable soluble pyridine nucleotide transhydrogenase SthA (STH) (NAD(P)(+) transhydrogenase [B-specific]) (nicotinamide nucleot 0.0014 0.0024 0.0042
Brugia malayi GTP-binding regulatory protein Gs alpha-S chain, putative 0.0136 0.1381 0.2266
Echinococcus granulosus sodium and chloride dependent glycine 0.0017 0.0053 0.0066
Mycobacterium ulcerans lipase LipD 0.0074 0.0693 0.1136
Echinococcus granulosus Sugar transporter ERD6 protein 0.003 0.0203 0.0252
Echinococcus granulosus cpg binding protein 0.0033 0.0234 0.029
Brugia malayi ImpB/MucB/SamB family protein 0.0019 0.0078 0.0124
Echinococcus multilocularis snurportin 1 0.0333 0.3579 0.4439
Echinococcus granulosus nicotinic acetylcholine receptor a11 subunit 0.0024 0.0141 0.0174
Echinococcus multilocularis jumonji domain containing protein 0.0039 0.0309 0.0383
Onchocerca volvulus 0.003 0.0203 0.036
Mycobacterium ulcerans flavoprotein disulfide reductase 0.0014 0.0024 0.0035
Entamoeba histolytica Acid sphingomyelinase-like phosphodiesterase, putative 0.0088 0.0849 0.2537
Onchocerca volvulus 0.003 0.0203 0.036
Echinococcus granulosus guanine nucleotide binding protein Gs subunit 0.0136 0.1381 0.1712
Schistosoma mansoni ran 0.0023 0.0124 0.0151
Mycobacterium ulcerans cytochrome P450 150A6 Cyp150A6 0.0039 0.0306 0.05
Brugia malayi hypoxia-induced factor 1 0.0163 0.1683 0.2764
Trichomonas vaginalis sugar transporter, putative 0.003 0.0203 0.0331
Brugia malayi Cytochrome P450 family protein 0.0039 0.0306 0.05
Brugia malayi latrophilin 2 splice variant baaae 0.0037 0.0279 0.0455
Trypanosoma cruzi PAB1-binding protein , putative 0.0053 0.0461 0.1168
Schistosoma mansoni hypothetical protein 0.0017 0.0058 0.0069
Brugia malayi Animal haem peroxidase family protein 0.0039 0.0306 0.05
Schistosoma mansoni rab geranylgeranyl transferase alpha subunit 0.0019 0.0078 0.0094
Mycobacterium tuberculosis Probable esterase LipL 0.0074 0.0693 0.1345
Mycobacterium tuberculosis Conserved protein 0.0074 0.0693 0.1345
Schistosoma mansoni tar DNA-binding protein 0.0062 0.0556 0.0687
Loa Loa (eye worm) nicotinic acetylcholine receptor alpha subunit 0.0024 0.0141 0.0231
Toxoplasma gondii NADPH-glutathione reductase 0.0014 0.0024 0.0032
Echinococcus multilocularis lysine specific demethylase 5A 0.0034 0.0251 0.0311
Brugia malayi Calcitonin receptor-like protein seb-1 0.0054 0.0469 0.0767
Loa Loa (eye worm) excitatory GABA receptor EXP-1A 0.0024 0.0141 0.0231
Brugia malayi Sodium:neurotransmitter symporter family protein 1, putative 0.0017 0.0053 0.0084
Trichomonas vaginalis cat eye syndrome critical region protein 2, cscr2, putative 0.0046 0.0382 0.0624
Leishmania major lysyl-tRNA synthetase, putative 0.0048 0.0401 0.1014
Plasmodium falciparum calcium-dependent protein kinase 2 0.0066 0.0602 0.06
Echinococcus granulosus Cys loop ligand gated ion channel subunit 0.0024 0.0141 0.0174
Treponema pallidum fructose-bisphosphate aldolase 0.0311 0.3339 1
Loa Loa (eye worm) animal heme peroxidase 0.0039 0.0306 0.0503
Loa Loa (eye worm) hypothetical protein 0.003 0.0203 0.0334
Trichomonas vaginalis glucosylceramidase, putative 0.0183 0.1911 0.3138
Echinococcus multilocularis synaptic vesicle 2 protein 0.003 0.0203 0.0252
Loa Loa (eye worm) hypothetical protein 0.0017 0.0053 0.0087
Echinococcus multilocularis 0.0039 0.0306 0.038
Mycobacterium tuberculosis Probable cytochrome P450 144 Cyp144 0.0039 0.0306 0.0592
Brugia malayi Cation transporter family protein 0.0024 0.0141 0.0227
Onchocerca volvulus 0.003 0.0201 0.0354
Plasmodium falciparum dihydrolipoyl dehydrogenase, mitochondrial 0.0014 0.0024 0.0021
Toxoplasma gondii hypothetical protein 0.0171 0.1777 0.2684
Brugia malayi Cam kinase protein 1 0.0066 0.0602 0.0986
Echinococcus multilocularis diuretic hormone 44 receptor GPRdih2 0.0017 0.0058 0.0072
Schistosoma mansoni importin beta-1 0.0031 0.0216 0.0265
Loa Loa (eye worm) hypothetical protein 0.0049 0.0411 0.0675
Onchocerca volvulus 0.0039 0.0306 0.0555
Echinococcus granulosus carbonic anhydrase 0.0171 0.1777 0.2204
Brugia malayi hypothetical protein 0.013 0.1323 0.2171
Echinococcus granulosus nicotinic acetylcholine receptor subunit alpha 8 0.0024 0.0141 0.0174
Schistosoma mansoni nAChR subunit (ShAR1-beta2-like) 0.0024 0.0141 0.0172
Onchocerca volvulus 0.003 0.0203 0.036
Onchocerca volvulus 0.0017 0.0053 0.0073
Brugia malayi PAS domain containing protein 0.0053 0.0454 0.0743
Mycobacterium ulcerans dihydrolipoamide dehydrogenase, LpdB 0.0014 0.0024 0.0035
Echinococcus granulosus GPCR family 2 0.0017 0.0058 0.0072
Schistosoma mansoni gcn5proteinral control of amino-acid synthesis 5-like 2 gcnl2 0.0157 0.1615 0.2001
Schistosoma mansoni Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) 0.0136 0.1381 0.171
Mycobacterium tuberculosis Lysyl-tRNA synthetase 1 LysS (lysine--tRNA ligase 1) (LysRS 1) (lysine translase) 0.0041 0.032 0.0619
Onchocerca volvulus Huntingtin homolog 0.013 0.1323 0.2493
Loa Loa (eye worm) hypothetical protein 0.0039 0.0306 0.0503
Mycobacterium tuberculosis Probable cytochrome P450 140 Cyp140 0.0039 0.0306 0.0592
Loa Loa (eye worm) CAMK/CAMK2 protein kinase 0.0066 0.0602 0.0989
Mycobacterium tuberculosis Probable cytochrome P450 143 Cyp143 0.0039 0.0306 0.0592
Leishmania major acetoin dehydrogenase e3 component-like protein 0.0014 0.0024 0.0054
Toxoplasma gondii transporter, major facilitator family protein 0.003 0.0203 0.0304
Echinococcus granulosus glycyl tRNA synthetase 0.0012 0.0002 0.0003
Loa Loa (eye worm) hypothetical protein 0.003 0.0203 0.0334
Brugia malayi Sodium:neurotransmitter symporter family protein 0.0017 0.0053 0.0084
Trypanosoma brucei importin beta-1 subunit, putative 0.0031 0.0216 0.0543
Trichomonas vaginalis sugar transporter, putative 0.003 0.0203 0.0331
Trichomonas vaginalis sugar transporter, putative 0.003 0.0203 0.0331
Trichomonas vaginalis chromodomain helicase DNA binding protein, putative 0.0018 0.007 0.0112
Echinococcus granulosus solute carrier family 2 facilitated glucose 0.0214 0.2254 0.2796
Loa Loa (eye worm) aryl Hydrocarbon receptor Associated protein family member 0.0014 0.002 0.0033
Loa Loa (eye worm) ACC-1 protein 0.0024 0.0141 0.0231
Toxoplasma gondii calcium-dependent protein kinase CDPK3 0.0066 0.0602 0.0908
Mycobacterium tuberculosis Probable dehydrogenase 0.0092 0.0893 0.1733
Brugia malayi hypothetical protein 0.0053 0.0461 0.0755
Echinococcus granulosus histone lysine methyltransferase setb 0.0062 0.0554 0.0687
Mycobacterium leprae PROBABLE NADH DEHYDROGENASE NDH 0.0092 0.0893 0.5703
Schistosoma mansoni histone-lysine n-methyltransferase setb1 0.0062 0.0554 0.0685
Mycobacterium ulcerans cytochrome P450 108B4 Cyp108B4 0.0039 0.0306 0.05
Trichomonas vaginalis CAMK family protein kinase 0.005 0.0422 0.069
Plasmodium falciparum protein kinase 7 0.0605 0.6614 0.6613
Loa Loa (eye worm) LGC-31 protein 0.0024 0.0141 0.0231
Brugia malayi hypothetical protein 0.0176 0.1835 0.3014
Echinococcus multilocularis aryl hydrocarbon receptor 0.0014 0.002 0.0025
Onchocerca volvulus 0.003 0.0203 0.036
Echinococcus granulosus lysine specific demethylase 5A 0.0036 0.0271 0.0336
Echinococcus multilocularis sodium and chloride dependent glycine 0.0017 0.0053 0.0066
Loa Loa (eye worm) hypothetical protein 0.0024 0.0141 0.0231
Toxoplasma gondii GTP-binding nuclear protein ran/tc4 0.0023 0.0124 0.0184
Chlamydia trachomatis proline--tRNA ligase 0.0023 0.0121 0.2978
Schistosoma mansoni peroxidasin 0.0039 0.0306 0.0377
Trichomonas vaginalis glucosylceramidase, putative 0.0279 0.2981 0.4898
Brugia malayi Sodium:neurotransmitter symporter family protein 0.0017 0.0053 0.0084
Schistosoma mansoni sodium-dependent neurotransmitter transporter 0.0017 0.0053 0.0063
Toxoplasma gondii cell-cycle-associated protein kinase MAPK, putative 0.0346 0.3728 0.5635
Trichomonas vaginalis bromodomain-containing protein, putative 0.0046 0.0382 0.0624
Trypanosoma brucei DNA polymerase eta, putative 0.0019 0.0078 0.0192
Mycobacterium ulcerans integral membrane transport protein 0.003 0.0203 0.0331
Echinococcus granulosus Ataxin 2 N terminaldomain containing protein 0.0024 0.0134 0.0166
Echinococcus multilocularis dna polymerase eta 0.0019 0.0078 0.0096
Echinococcus multilocularis glutamyl tRNA synthetase cytoplasmic 0.0064 0.0584 0.0724
Brugia malayi hypothetical protein 0.003 0.0203 0.0331
Echinococcus multilocularis cadherin EGF LAG seven pass G type receptor 0.0017 0.0058 0.0072
Onchocerca volvulus 0.0024 0.0141 0.024
Loa Loa (eye worm) GTP-binding regulatory protein Gs alpha-S chain 0.0136 0.1381 0.2269
Loa Loa (eye worm) hypothetical protein 0.0024 0.0141 0.0231
Mycobacterium ulcerans cytochrome P450 185A4 Cyp185A4 0.0039 0.0306 0.05
Mycobacterium ulcerans esterase/lipase LipP 0.0074 0.0693 0.1136
Schistosoma mansoni bromodomain-containing nuclear protein 1 brd1 0.0028 0.0185 0.0226
Echinococcus granulosus sodium dependent neurotransmitter transporter 0.0017 0.0053 0.0066
Echinococcus granulosus solute carrier family 2 facilitated glucose 0.0214 0.2254 0.2796
Echinococcus multilocularis microtubule associated protein 2 0.0734 0.8063 1
Trichomonas vaginalis fructose-bisphosphate aldolase, putative 0.0311 0.3339 0.5486
Leishmania major GTP-binding protein, putative 0.0023 0.0124 0.0309
Loa Loa (eye worm) hypothetical protein 0.0024 0.0141 0.0231
Mycobacterium ulcerans cytochrome P450 189A7 Cyp189A7 0.0039 0.0306 0.05
Brugia malayi RNA recognition motif domain containing protein 0.0062 0.0556 0.0911
Mycobacterium ulcerans cytochrome P450 123A3 Cyp123A3 0.0039 0.0306 0.05
Loa Loa (eye worm) hypothetical protein 0.003 0.0203 0.0334
Trichomonas vaginalis conserved hypothetical protein 0.0014 0.002 0.003
Trichomonas vaginalis sugar transporter, putative 0.003 0.0203 0.0331
Brugia malayi bifunctional aminoacyl-tRNA synthetase 0.0064 0.0584 0.0956
Trypanosoma cruzi cytochrome P450, putative 0.0039 0.0306 0.0773
Echinococcus multilocularis chromobox protein 1 0.0068 0.0625 0.0775
Echinococcus granulosus chromobox protein 1 0.0068 0.0625 0.0775
Echinococcus multilocularis PHD finger protein rhinoceros 0.0028 0.0185 0.0229
Loa Loa (eye worm) sugar transporter 0.0214 0.2254 0.3705
Trypanosoma brucei glucose transporter 1E 0.0066 0.0608 0.1542
Leishmania major 3-oxoacyl-(acyl-carrier protein) reductase, putative 0.0118 0.118 0.2998
Trichomonas vaginalis lysyl-tRNA synthetase, putative 0.0042 0.0335 0.0547
Brugia malayi beta-lactamase 0.0074 0.0693 0.1136
Plasmodium vivax proline--tRNA ligase, putative 0.0075 0.0703 0.07
Plasmodium falciparum thioredoxin reductase 0.004 0.0317 0.0315
Onchocerca volvulus Huntingtin homolog 0.013 0.1323 0.2493
Onchocerca volvulus 0.003 0.0203 0.036
Echinococcus multilocularis dna polymerase kappa 0.0019 0.0078 0.0096
Schistosoma mansoni norepinephrine/norepinephrine transporter 0.0017 0.0053 0.0063
Schistosoma mansoni glutamyl-tRNA synthetase cytoplasmic (glutamate--tRNA ligase) (glurs) 0.0064 0.0584 0.0722
Loa Loa (eye worm) hypothetical protein 0.003 0.0203 0.0334
Echinococcus multilocularis solute carrier family 22 0.003 0.0203 0.0252
Echinococcus multilocularis solute carrier family 2 facilitated glucose 0.0214 0.2254 0.2796
Schistosoma mansoni sodium-dependent amino acid transporter 0.0017 0.0053 0.0063
Onchocerca volvulus 0.003 0.0203 0.036
Schistosoma mansoni family S12 unassigned peptidase (S12 family) 0.0074 0.0693 0.0857
Echinococcus granulosus single minded 2 0.0039 0.0302 0.0375
Leishmania major protein kinase, putative,polo-like protein kinase, putative 0.0096 0.094 0.2386
Echinococcus multilocularis geminin 0.0524 0.5709 0.7081
Trypanosoma brucei glucose transporter, putative 0.0066 0.0608 0.1542
Loa Loa (eye worm) hypothetical protein 0.0017 0.0053 0.0087
Echinococcus multilocularis sodium:chloride dependent neurotransmitter 0.011 0.1091 0.1353
Loa Loa (eye worm) serotonin transporter b 0.0017 0.0053 0.0087
Trypanosoma brucei glucose transporter, putative 0.0066 0.0608 0.1542
Schistosoma mansoni lysyl-tRNA synthetase 0.0048 0.0401 0.0494
Mycobacterium leprae conserved hypothetical protein 0.0074 0.0693 0.4425
Trypanosoma brucei carbonic anhydrase-like protein 0.0364 0.3932 1
Brugia malayi jmjC domain containing protein 0.0036 0.0271 0.0442
Brugia malayi Sugar transporter family protein 0.003 0.0203 0.0331
Echinococcus granulosus glycine receptor subunit alpha 1 0.0024 0.0141 0.0174
Echinococcus granulosus histone acetyltransferase KAT2B 0.0152 0.1566 0.1943
Mycobacterium ulcerans prolyl-tRNA synthetase 0.0023 0.0121 0.0195
Loa Loa (eye worm) hypothetical protein 0.0024 0.0141 0.0231
Trichomonas vaginalis CAMK family protein kinase 0.0096 0.094 0.1542
Echinococcus multilocularis Cys loop ligand gated ion channel subunit 0.0024 0.0141 0.0174
Loa Loa (eye worm) MH2 domain-containing protein 0.0129 0.1307 0.2148
Loa Loa (eye worm) PLK/PLK1 protein kinase 0.0096 0.094 0.1545
Schistosoma mansoni neurotransmitter gated ion channel 0.0013 0.0015 0.0016
Trichomonas vaginalis fructose-bisphosphate aldolase, putative 0.0311 0.3339 0.5486
Brugia malayi Major Facilitator Superfamily protein 0.003 0.0203 0.0331
Schistosoma mansoni DNA polymerase eta 0.0019 0.0078 0.0094
Echinococcus multilocularis nAChR subunit 0.0024 0.0141 0.0174
Mycobacterium tuberculosis Lysyl-tRNA synthetase 2 LysX 0.0041 0.032 0.0619
Echinococcus multilocularis guanine nucleotide binding protein G(s) subunit 0.0136 0.1381 0.1712
Schistosoma mansoni aryl hydrocarbon receptor 0.0053 0.0454 0.0561
Onchocerca volvulus 0.003 0.0203 0.036
Brugia malayi beta-lactamase family protein 0.0074 0.0693 0.1136
Loa Loa (eye worm) hypothetical protein 0.0014 0.002 0.0033
Mycobacterium tuberculosis Conserved protein 0.0074 0.0693 0.1345
Giardia lamblia GTP-binding nuclear protein RAN/TC4 0.0023 0.0124 0.0364
Trypanosoma cruzi STE group serine/threonine-protein kinase, putative 0.0018 0.0069 0.0171
Echinococcus multilocularis cpg binding protein 0.0033 0.0234 0.029
Schistosoma mansoni glucose transport protein 0.0214 0.2254 0.2794
Trypanosoma brucei DNA polymerase kappa, putative 0.0013 0.0013 0.0026
Brugia malayi nicotinic acetylcholine receptor alpha subunit, putative 0.0024 0.0141 0.0227
Trichomonas vaginalis chromodomain helicase DNA binding protein, putative 0.0018 0.007 0.0112
Mycobacterium ulcerans epoxide hydrolase EphA 0.018 0.1874 0.3077
Echinococcus multilocularis transfer RNA-Lys 0.0039 0.0302 0.0375
Mycobacterium tuberculosis Dihydrolipoamide dehydrogenase LpdC (lipoamide reductase (NADH)) (lipoyl dehydrogenase) (dihydrolipoyl dehydrogenase) (diaphoras 0.0102 0.1007 0.1956
Trichomonas vaginalis chromodomain-helicase-DNA-binding protein, putative 0.0015 0.0034 0.0052
Brugia malayi acetylcholine receptor protein, alpha-like chain, putative 0.0024 0.0141 0.0227
Trichomonas vaginalis conserved hypothetical protein 0.003 0.0203 0.0331
Toxoplasma gondii histone lysine methyltransferase SET/SUV39 0.0062 0.0554 0.0835
Plasmodium vivax hypothetical protein, conserved 0.0017 0.0053 0.0051
Echinococcus granulosus serine:threonine protein kinase PLK1 0.0096 0.094 0.1166
Schistosoma mansoni chromobox protein 0.0068 0.0625 0.0773
Mycobacterium ulcerans lysyl-tRNA synthetase 0.0048 0.0401 0.0655
Onchocerca volvulus 0.0017 0.0053 0.0073
Loa Loa (eye worm) hypothetical protein 0.0024 0.0141 0.0231
Giardia lamblia Histone acetyltransferase GCN5 0.0042 0.0339 0.1009
Schistosoma mansoni jumonji/arid domain-containing protein 0.0036 0.0271 0.0333
Trichomonas vaginalis conserved hypothetical protein 0.0214 0.2254 0.3703
Loa Loa (eye worm) hypothetical protein 0.0039 0.0306 0.0503
Mycobacterium ulcerans aldehyde dehydrogenase 0.0124 0.1257 0.2063
Trypanosoma cruzi PAS-domain containing phosphoglycerate kinase, putative 0.0014 0.002 0.0046
Echinococcus multilocularis glycine receptor subunit alpha 1 0.0024 0.0141 0.0174
Schistosoma mansoni family S12 unassigned peptidase (S12 family) 0.0074 0.0693 0.0857
Loa Loa (eye worm) hypothetical protein 0.0024 0.0141 0.0231
Trypanosoma brucei sugar transporter, putative 0.003 0.0203 0.0512
Plasmodium falciparum glutathione reductase 0.004 0.0317 0.0315
Plasmodium vivax lysine--tRNA ligase, putative 0.0048 0.0401 0.0399
Echinococcus granulosus histone acetyltransferase KAT2B 0.0046 0.0382 0.0473
Brugia malayi Neurotransmitter-gated ion-channel ligand binding domain containing protein 0.0024 0.0141 0.0227
Trichomonas vaginalis guanylate cyclase, putative 0.0014 0.002 0.003
Mycobacterium ulcerans aldehyde dehydrogenase 0.0124 0.1257 0.2063
Loa Loa (eye worm) hypothetical protein 0.003 0.0203 0.0334
Mycobacterium ulcerans cytochrome P450 143A4 Cyp143A4 0.0039 0.0306 0.05
Mycobacterium tuberculosis Cytochrome P450 51 Cyp51 (CYPL1) (P450-L1A1) (sterol 14-alpha demethylase) (lanosterol 14-alpha demethylase) (P450-14DM) 0.0039 0.0306 0.0592
Loa Loa (eye worm) hypothetical protein 0.0024 0.0141 0.0231
Trichomonas vaginalis CAMK family protein kinase 0.0096 0.094 0.1542
Schistosoma mansoni hypothetical protein 0.0017 0.0058 0.0069
Brugia malayi Animal haem peroxidase family protein 0.0039 0.0306 0.05
Echinococcus granulosus calcium:calmodulin dependent protein kinase type 0.0066 0.0602 0.0747
Brugia malayi F/Y-rich N-terminus family protein 0.0021 0.0102 0.0164
Loa Loa (eye worm) hypothetical protein 0.0017 0.0053 0.0087
Trichomonas vaginalis sugar transporter, putative 0.003 0.0203 0.0331
Trichomonas vaginalis sugar transporter, putative 0.003 0.0203 0.0331
Trichomonas vaginalis sugar transporter, putative 0.003 0.0203 0.0331
Onchocerca volvulus 0.003 0.0203 0.036
Leishmania major cytochrome p450-like protein 0.0039 0.0306 0.0773
Schistosoma mansoni carbonic anhydrase 0.0171 0.1777 0.2202
Toxoplasma gondii Sodium:neurotransmitter symporter family protein 0.0017 0.0053 0.0077
Loa Loa (eye worm) hypothetical protein 0.0024 0.0141 0.0231
Trichomonas vaginalis glucose transporter, putative 0.0066 0.0608 0.0996
Mycobacterium tuberculosis Probable reductase 0.0092 0.0893 0.1733
Schistosoma mansoni microtubule-associated protein tau 0.0734 0.8063 1
Giardia lamblia Fructose-bisphosphate aldolase 0.0311 0.3339 1
Trichomonas vaginalis fructose-bisphosphate aldolase, putative 0.0311 0.3339 0.5486
Loa Loa (eye worm) GTP-binding nuclear protein RAN/TC4 0.0023 0.0124 0.0203
Trichomonas vaginalis CAMK family protein kinase 0.0096 0.094 0.1542
Echinococcus granulosus uncharacterized sodium dependent transporter 0.0017 0.0053 0.0066
Mycobacterium ulcerans hypothetical protein 0.0074 0.0693 0.1136
Brugia malayi PHD-finger family protein 0.0028 0.0185 0.03
Loa Loa (eye worm) jmjC domain-containing protein 0.0036 0.0271 0.0445
Loa Loa (eye worm) O-glycosyl hydrolase family 30 protein 0.0279 0.2981 0.49
Mycobacterium leprae Probable lysyl-tRNA synthase LysS (lysine--tRNA ligase 1) (LysRS 1) (lysine translase) 0.0041 0.032 0.2038
Schistosoma mansoni protein kinase 0.0066 0.0602 0.0744
Brugia malayi Carbonic anhydrase like protein 2 precursor 0.0171 0.1777 0.2918
Onchocerca volvulus Peroxidasin homolog 0.0039 0.0306 0.0555
Echinococcus granulosus glycine receptor subunit beta 0.0024 0.0141 0.0174
Schistosoma mansoni glucose transport protein 0.0214 0.2254 0.2794
Brugia malayi Pre-SET motif family protein 0.0425 0.4607 0.7571
Onchocerca volvulus Heterochromatin protein 1 homolog 0.0038 0.0292 0.0529
Schistosoma mansoni sodium/chloride dependent transporter 0.0017 0.0053 0.0063
Trypanosoma cruzi STE/STE11 serine/threonine-protein kinase, putative 0.0018 0.0069 0.0171
Loa Loa (eye worm) hypothetical protein 0.013 0.1323 0.2174
Loa Loa (eye worm) hypothetical protein 0.0064 0.0584 0.096
Trichomonas vaginalis chromobox protein, putative 0.0041 0.0325 0.053
Toxoplasma gondii pyruvate dehydrogenase complex subunit PDH-E3II 0.0014 0.0024 0.0032
Brugia malayi gamma-aminobutyric-acid receptor beta subunit precursor 0.0024 0.0141 0.0227
Onchocerca volvulus 0.0073 0.0678 0.1264
Plasmodium vivax dihydrolipoyl dehydrogenase, apicoplast, putative 0.0014 0.0024 0.0021
Trichomonas vaginalis penicillin-binding protein, putative 0.0074 0.0693 0.1136
Brugia malayi Sodium:neurotransmitter symporter family protein 0.0017 0.0053 0.0084
Schistosoma mansoni nAChR subunit 0.0024 0.0141 0.0172
Echinococcus multilocularis sodium dependent neurotransmitter transporter 0.0017 0.0053 0.0066
Trypanosoma cruzi hexose transporter, putative 0.0066 0.0608 0.1542
Onchocerca volvulus Peroxidase homolog 0.0039 0.0306 0.0555
Onchocerca volvulus 0.0024 0.0141 0.024
Trichomonas vaginalis fructose-bisphosphate aldolase, putative 0.0311 0.3339 0.5486
Echinococcus multilocularis carbonic anhydrase 0.0171 0.1777 0.2204
Brugia malayi glutaminase DH11.1 0.0557 0.6085 1
Schistosoma mansoni sugar transporter 0.003 0.0203 0.025
Loa Loa (eye worm) sugar transporter 0.003 0.0203 0.0334
Trypanosoma cruzi PAS-domain containing phosphoglycerate kinase, putative 0.0014 0.002 0.0046
Trypanosoma brucei myo-inositol/proton symporter (MIT) 0.003 0.0203 0.0512
Trichomonas vaginalis myo-inositol transporter, putative 0.003 0.0203 0.0331
Echinococcus multilocularis nAChR subunit 0.0013 0.0015 0.0018
Trichomonas vaginalis Importin beta-1 subunit, putative 0.0025 0.015 0.0243
Mycobacterium tuberculosis Possible DNA-damage-inducible protein P DinP (DNA polymerase V) (pol IV 2) (DNA nucleotidyltransferase (DNA-directed)) 0.0019 0.0078 0.0147
Trichomonas vaginalis conserved hypothetical protein 0.003 0.0203 0.0331
Mycobacterium ulcerans cytochrome P450 188A3 Cyp188A3 0.0039 0.0306 0.05
Loa Loa (eye worm) beta-LACTamase domain containing family member 0.0074 0.0693 0.1139
Trichomonas vaginalis fructose-bisphosphate aldolase, putative 0.0311 0.3339 0.5486
Onchocerca volvulus 0.0017 0.0053 0.0073
Loa Loa (eye worm) hypothetical protein 0.0024 0.0141 0.0231
Leishmania major importin beta-1 subunit, putative 0.0025 0.015 0.0376
Mycobacterium leprae DIHYDROLIPOAMIDE DEHYDROGENASE LPD (LIPOAMIDE REDUCTASE (NADH)) (LIPOYL DEHYDROGENASE) (DIHYDROLIPOYL DEHYDROGENASE) (DIAPHORASE 0.0102 0.1007 0.6436
Trichomonas vaginalis sugar transporter, putative 0.003 0.0203 0.0331
Trypanosoma cruzi dihydrolipoamide dehydrogenase, putative 0.0014 0.0024 0.0054
Loa Loa (eye worm) hypothetical protein 0.0024 0.0141 0.0231
Echinococcus granulosus chromobox protein 1 0.0068 0.0625 0.0775
Trichomonas vaginalis sugar transporter, putative 0.003 0.0203 0.0331
Mycobacterium leprae putative cytochrome p450 0.0039 0.0306 0.1946
Onchocerca volvulus 0.0017 0.0053 0.0073
Plasmodium vivax SET domain protein, putative 0.0062 0.0554 0.0552
Chlamydia trachomatis Ssodium-dependent amino acid transporter 0.0017 0.0053 0.1278
Brugia malayi Cation transporter family protein 0.0024 0.0141 0.0227
Echinococcus granulosus acetylcholine receptor subunit beta 1 0.0024 0.0141 0.0174
Echinococcus multilocularis beta LACTamase domain containing family member 0.0074 0.0693 0.0859
Trichomonas vaginalis glucosylceramidase, putative 0.0193 0.2021 0.3319
Loa Loa (eye worm) hypothetical protein 0.0074 0.0693 0.1139
Trichomonas vaginalis CAMK family protein kinase 0.0096 0.094 0.1542
Schistosoma mansoni jumonji domain containing protein 0.0074 0.0692 0.0855
Echinococcus multilocularis Aryl hydrocarbon receptor nuclear 0.0014 0.002 0.0025
Loa Loa (eye worm) hypothetical protein 0.0024 0.0141 0.0231
Schistosoma mansoni cpg binding protein 0.0033 0.0234 0.0287
Brugia malayi GTP-binding nuclear protein RAN/TC4 0.0023 0.0124 0.02
Loa Loa (eye worm) major facilitator superfamily transporter 0.003 0.0203 0.0334
Echinococcus multilocularis gcn5proteinral control of amino acid synthesis 0.0157 0.1615 0.2003
Echinococcus multilocularis peregrin 0.0032 0.0227 0.0282
Echinococcus granulosus jumonji domain containing protein 0.0039 0.0309 0.0383
Toxoplasma gondii prolyl-tRNA synthetase (ProRS) 0.0075 0.0703 0.1059
Brugia malayi jmjC domain containing protein 0.0093 0.0905 0.1484
Onchocerca volvulus 0.0074 0.0693 0.1293
Schistosoma mansoni aldehyde dehydrogenase 0.0124 0.1257 0.1557
Treponema pallidum sodium- and chloride- dependent transporter 0.0017 0.0053 0.0153
Schistosoma mansoni hypothetical protein 0.0037 0.0279 0.0343
Trichomonas vaginalis sugar transporter, putative 0.003 0.0203 0.0331
Schistosoma mansoni 3-hydroxyacyl-CoA dehydrogenase 0.0118 0.118 0.1461
Loa Loa (eye worm) ACC-1 protein 0.0024 0.0141 0.0231
Leishmania major cytochrome p450-like protein 0.0039 0.0306 0.0773
Echinococcus granulosus glycine receptor subunit alpha 1 0.0024 0.0141 0.0174
Trypanosoma cruzi dihydrolipoamide dehydrogenase, putative 0.0014 0.0024 0.0054
Trypanosoma brucei polo-like protein kinase 0.0096 0.094 0.2386
Loa Loa (eye worm) blistered cuticle protein 3 0.0039 0.0306 0.0503
Brugia malayi Cation transporter family protein 0.0024 0.0141 0.0227
Entamoeba histolytica Ran family GTPase 0.0023 0.0124 0.0364
Trypanosoma brucei lysyl-tRNA synthetase, putative 0.0048 0.0401 0.1014
Echinococcus multilocularis importin subunit beta 1 0.0031 0.0216 0.0267
Schistosoma mansoni nAChR subunit (ShAR1-alpha-like) 0.0024 0.0141 0.0172
Echinococcus granulosus nAChR subunit 0.0024 0.0141 0.0174
Trypanosoma cruzi hexose transporter, putative 0.003 0.0203 0.0512
Loa Loa (eye worm) hypothetical protein 0.0074 0.0693 0.1139
Loa Loa (eye worm) hypothetical protein 0.003 0.0201 0.033
Schistosoma mansoni sodium-dependent neurotransmitter transporter 0.0017 0.0053 0.0063
Trichomonas vaginalis conserved hypothetical protein 0.0027 0.0168 0.0273
Echinococcus multilocularis acetylcholine receptor subunit beta 1 0.0024 0.0141 0.0174
Loa Loa (eye worm) ImpB/MucB/SamB family protein 0.0019 0.0078 0.0128
Mycobacterium ulcerans cytochrome P450 124A1, Cyp124A1 0.0039 0.0306 0.05
Loa Loa (eye worm) hypothetical protein 0.003 0.0203 0.0334
Trypanosoma brucei trypanothione reductase 0.004 0.0317 0.0801
Mycobacterium tuberculosis Probable cytochrome P450 125 Cyp125 0.0039 0.0306 0.0592
Entamoeba histolytica acetyltransferase, GNAT family 0.0042 0.0339 0.1009
Trypanosoma cruzi DNA polymerase kappa, putative 0.0019 0.0078 0.0192
Trichomonas vaginalis CAMK family protein kinase 0.0096 0.094 0.1542
Schistosoma mansoni Cys-loop ligand gated ion channel subunit 0.0024 0.0141 0.0172
Trypanosoma brucei DNA polymerase kappa, putative 0.0019 0.0078 0.0192
Trichomonas vaginalis sugar transporter, putative 0.003 0.0203 0.0331
Mycobacterium leprae Possible regulatory protein 0.0014 0.002 0.0116
Trichomonas vaginalis ran, putative 0.0023 0.0124 0.02
Onchocerca volvulus 0.0024 0.0141 0.024
Loa Loa (eye worm) hypothetical protein 0.003 0.0203 0.0334
Toxoplasma gondii cytochrome p450 superfamily protein 0.0039 0.0306 0.046
Schistosoma mansoni sugar transporter 0.003 0.0203 0.025
Trichomonas vaginalis sugar transporter, putative 0.003 0.0203 0.0331
Mycobacterium leprae Probable prolyl tRNA synthetase ProS 0.0064 0.0584 0.3726
Schistosoma mansoni chromobox protein 0.0068 0.0625 0.0773
Plasmodium falciparum dihydrolipoyl dehydrogenase, apicoplast 0.0014 0.0024 0.0021
Brugia malayi hypothetical protein 0.003 0.0203 0.0331
Loa Loa (eye worm) hypothetical protein 0.0024 0.0141 0.0231
Leishmania major dihydrolipoamide dehydrogenase, putative 0.0014 0.0024 0.0054
Echinococcus granulosus aryl hydrocarbon receptor 0.0014 0.002 0.0025
Mycobacterium tuberculosis Probable cytochrome P450 128 Cyp128 0.0039 0.0306 0.0592
Toxoplasma gondii sugar transporter ST3 0.003 0.0203 0.0304
Brugia malayi Sugar transporter family protein 0.003 0.0203 0.0331
Echinococcus multilocularis solute carrier family 22 0.003 0.0203 0.0252
Brugia malayi chromobox protein homolog 3 0.0038 0.0292 0.0477
Giardia lamblia Lysyl-tRNA synthetase 0.0048 0.0401 0.1194
Echinococcus granulosus dnaJ subfamily B 0.0442 0.4799 0.5952
Mycobacterium tuberculosis Probable esterase/lipase LipP 0.0074 0.0693 0.1345
Leishmania major protein kinase, putative 0.0018 0.0069 0.0171
Echinococcus granulosus solute carrier family 2 facilitated glucose 0.0214 0.2254 0.2796
Brugia malayi excitatory GABA receptor EXP-1A 0.0024 0.0141 0.0227
Entamoeba histolytica hypothetical protein 0.0013 0.0015 0.0038
Schistosoma mansoni ran 0.0023 0.0124 0.0151
Brugia malayi Heterochromatin protein 1 0.0068 0.0625 0.1024
Loa Loa (eye worm) hypothetical protein 0.0039 0.0306 0.0503
Trypanosoma brucei GTP-binding nuclear protein rtb2, putative 0.0023 0.0124 0.0309
Schistosoma mansoni tar DNA-binding protein 0.0062 0.0556 0.0687
Brugia malayi Hypothetical glycine receptor like protein T20B12.9 in chromosome III 0.0024 0.0141 0.0227
Mycobacterium ulcerans fructose-bisphosphate aldolase 0.0152 0.1563 0.2567
Loa Loa (eye worm) CHromoDomain protein family member 0.0013 0.0012 0.0019
Trichomonas vaginalis sugar transporter, putative 0.0066 0.0608 0.0996
Trypanosoma cruzi cytochrome p450-like protein, putative 0.0039 0.0306 0.0773
Echinococcus multilocularis carbonic anhydrase II 0.0364 0.3932 0.4877
Loa Loa (eye worm) cytochrome P450 0.0039 0.0306 0.0503
Schistosoma mansoni Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) 0.0136 0.1381 0.171
Onchocerca volvulus 0.003 0.0203 0.036
Trypanosoma brucei bifunctional aminoacyl-tRNA synthetase, putative 0.0075 0.0703 0.1782
Loa Loa (eye worm) hypothetical protein 0.0013 0.0015 0.0024
Loa Loa (eye worm) animal heme peroxidase 0.0039 0.0306 0.0503
Schistosoma mansoni nAChR subunit 0.0024 0.0141 0.0172
Trypanosoma cruzi importin beta-1 subunit, putative 0.0025 0.015 0.0376
Onchocerca volvulus 0.003 0.0203 0.036
Mycobacterium ulcerans cytochrome P450 125A7 Cyp125A7 0.0039 0.0306 0.05
Loa Loa (eye worm) hypothetical protein 0.0031 0.0216 0.0354
Trichomonas vaginalis conserved hypothetical protein 0.0066 0.0608 0.0996
Trichomonas vaginalis mercuric reductase, putative 0.0014 0.0024 0.0035
Echinococcus multilocularis General substrate transporter 0.0184 0.1919 0.238
Loa Loa (eye worm) latrophilin receptor protein 2 0.0017 0.0058 0.0095
Loa Loa (eye worm) heterochromatin protein 1 0.0068 0.0625 0.1027
Treponema pallidum prolyl-tRNA synthetase 0.0023 0.0121 0.0356
Mycobacterium tuberculosis Probable aldehyde dehydrogenase 0.0124 0.1257 0.2443
Mycobacterium tuberculosis Possible conserved lipoprotein LpqK 0.0074 0.0693 0.1345
Brugia malayi major facilitator superfamily protein 0.003 0.0203 0.0331
Leishmania major protein kinase, putative 0.0018 0.0069 0.0171
Leishmania major cytochrome p450-like protein 0.0039 0.0306 0.0773
Mycobacterium tuberculosis Probable cytochrome P450 132 Cyp132 0.0039 0.0306 0.0592
Mycobacterium tuberculosis Probable dicarboxylic acid transport integral membrane protein KgtP (dicarboxylate transporter) 0.003 0.0203 0.0392
Echinococcus multilocularis aldehyde dehydrogenase, mitochondrial 0.0124 0.1257 0.1559
Mycobacterium tuberculosis Probable membrane NADH dehydrogenase NdhA 0.0092 0.0893 0.1733
Echinococcus multilocularis uncharacterized sodium dependent transporter 0.0017 0.0053 0.0066
Brugia malayi TAR-binding protein 0.0062 0.0556 0.0911
Loa Loa (eye worm) hypothetical protein 0.0066 0.0602 0.0989
Trypanosoma brucei hypothetical protein, conserved 0.0074 0.0693 0.1758
Toxoplasma gondii protein kinase, putative 0.0605 0.6614 1
Loa Loa (eye worm) hypothetical protein 0.003 0.0203 0.0334
Loa Loa (eye worm) hypothetical protein 0.0017 0.0053 0.0087
Echinococcus multilocularis solute carrier family 2 facilitated glucose 0.0214 0.2254 0.2796
Onchocerca volvulus Peroxidase homolog 0.0039 0.0306 0.0555
Trichomonas vaginalis glucosylceramidase, putative 0.0279 0.2981 0.4898
Schistosoma mansoni kinase 0.0051 0.0435 0.0537
Brugia malayi acetylcholine receptor, alpha-type subunit unc-38 precursor 0.0024 0.0141 0.0227
Echinococcus multilocularis nicotinic acetylcholine receptor a11 subunit 0.0024 0.0141 0.0174
Mycobacterium ulcerans short-chain type dehydrogenase/reductase 0.0118 0.118 0.1937
Loa Loa (eye worm) hypothetical protein 0.0039 0.0306 0.0503
Trypanosoma brucei glucose transporter, putative 0.0066 0.0608 0.1542
Trypanosoma brucei unspecified product 0.0013 0.0013 0.0026
Loa Loa (eye worm) hypothetical protein 0.003 0.0203 0.0334
Brugia malayi Eukaryotic-type carbonic anhydrase family protein 0.0364 0.3932 0.6461
Brugia malayi RNA, U transporter 1 0.0089 0.0856 0.1404
Echinococcus granulosus nicotinic acetylcholine receptor subunit type 0.0024 0.0141 0.0174
Brugia malayi Animal haem peroxidase family protein 0.0039 0.0306 0.05
Plasmodium falciparum ataxin-2 like protein, putative 0.0053 0.0461 0.0459
Schistosoma mansoni dihydrolipoamide dehydrogenase 0.0014 0.0024 0.0027
Schistosoma mansoni glucose transporter 0.003 0.0203 0.025
Loa Loa (eye worm) hypothetical protein 0.0017 0.0053 0.0087
Trichomonas vaginalis sugar transporter, putative 0.003 0.0203 0.0331
Mycobacterium ulcerans dihydrolipoamide dehydrogenase 0.0014 0.0024 0.0035
Echinococcus granulosus tar DNA binding protein 0.0062 0.0556 0.069
Echinococcus multilocularis serotonin transporter 0.0017 0.0053 0.0066
Trichomonas vaginalis sugar transporter, putative 0.003 0.0203 0.0331
Loa Loa (eye worm) glutaminase 0.0557 0.6085 1
Plasmodium falciparum amino acid transporter, putative 0.0017 0.0053 0.0051
Schistosoma mansoni carbonic anhydrase-related 0.0171 0.1777 0.2202
Onchocerca volvulus 0.003 0.0203 0.036
Onchocerca volvulus 0.003 0.0203 0.036
Loa Loa (eye worm) hypothetical protein 0.0013 0.0015 0.0024
Trypanosoma cruzi Lanosterol 14-alpha demethylase 0.0039 0.0306 0.0773
Mycobacterium ulcerans cytochrome P450 143A3 Cyp143A3 0.0039 0.0306 0.05
Trichomonas vaginalis DNA polymerase IV / kappa, putative 0.0019 0.0078 0.0124
Echinococcus multilocularis GTP binding nuclear protein Ran 0.0023 0.0124 0.0153
Loa Loa (eye worm) pigment dispersing factor receptor c 0.0054 0.0469 0.0771
Mycobacterium tuberculosis Probable cytochrome P450 monooxygenase 142 Cyp142 0.0039 0.0306 0.0592
Echinococcus granulosus synaptic vesicle 2 protein 0.003 0.0203 0.0252
Trichomonas vaginalis glucosylceramidase, putative 0.0279 0.2981 0.4898
Mycobacterium tuberculosis Conserved hypothetical protein 0.0019 0.0078 0.0147
Trypanosoma brucei glucose transporter, putative 0.0066 0.0608 0.1542
Mycobacterium ulcerans cytochrome P450 144A4 Cyp144A4 0.0039 0.0306 0.05
Leishmania major glucose transporter, lmgt1 0.0066 0.0608 0.1542
Trypanosoma cruzi STE group serine/threonine-protein kinase, putative 0.0018 0.0069 0.0171
Brugia malayi Major Facilitator Superfamily protein 0.003 0.0203 0.0331
Loa Loa (eye worm) glutamate-gated chloride channel alpha3A subunit 0.0024 0.0141 0.0231
Brugia malayi Thioredoxin reductase 0.004 0.0317 0.0518
Echinococcus multilocularis calcium:calmodulin dependent protein kinase type 0.0066 0.0602 0.0747
Trichomonas vaginalis sugar transporter, putative 0.003 0.0203 0.0331
Trypanosoma brucei dihydrolipoamide dehydrogenase, point mutation 0.0014 0.0024 0.0054
Toxoplasma gondii lysine-tRNA ligase 0.0048 0.0401 0.0603
Echinococcus multilocularis serine:threonine protein kinase PLK1 0.0096 0.094 0.1166
Echinococcus granulosus serotonin transporter 0.0017 0.0053 0.0066
Mycobacterium tuberculosis Probable fructose-bisphosphate aldolase Fba 0.0152 0.1563 0.3039
Mycobacterium ulcerans lysyl-tRNA synthetase 0.0048 0.0401 0.0655
Loa Loa (eye worm) cytochrome P450 family protein 0.0039 0.0306 0.0503
Leishmania major myo-inositol/proton symporter (MIT) 0.003 0.0203 0.0512
Brugia malayi Cytochrome P450 family protein 0.0039 0.0306 0.05
Trypanosoma brucei DNA polymerase IV, putative 0.0019 0.0078 0.0192
Trichomonas vaginalis sugar transporter, putative 0.003 0.0203 0.0331
Trichomonas vaginalis glucosylceramidase, putative 0.0183 0.1911 0.3138
Trypanosoma cruzi carbonic anhydrase-like protein, putative 0.0364 0.3932 1
Trypanosoma cruzi GTP-binding nuclear protein rtb2, putative 0.0023 0.0124 0.0309
Trypanosoma brucei DNA polymerase kappa, putative 0.0019 0.0078 0.0192
Trichomonas vaginalis adenylate cyclase, putative 0.0014 0.002 0.003
Mycobacterium tuberculosis NADPH-dependent mycothiol reductase Mtr 0.004 0.0317 0.0613
Trichomonas vaginalis D-aminoacylase, putative 0.0074 0.0693 0.1136
Trypanosoma cruzi carbonic anhydrase-like protein, putative 0.0364 0.3932 1
Loa Loa (eye worm) cytochrome P450 family protein 0.0136 0.1384 0.2274
Echinococcus multilocularis chromodomain helicase DNA binding protein 4 0.0013 0.0012 0.0014

Activities

No activities found for this compound.

Phenotypes

Whole-cell/tissue/organism interactions

We have no records of whole-cell/tissue assays done with this compound What does this mean?

Many chemical entities in TDR Targets come from high-throughput screenings with whole cells or tissue samples, and not all assayed compounds have been tested against a single a single target protein, probably because they get ruled out during screening process. Even if these compounds may have not been of interest in the original screening, they may come as interesting leads for other screening assays. Furthermore, we may be able to propose drug-target associations using chemical similarities and network patterns.

Annotated phenotypes:

We have no manually annotated phenotypes for this drug. What does this mean? / Care to help?
In TDR Targets, information about phenotypes that are caused by drugs, or by genetic manipulation of cells (e.g. gene knockouts or knockdowns) is manually curated from the literature. These descriptions help to describe the potential of the target for drug development. If no information is available for this gene or if the information is incomplete, this may mean that i) the papers containing this information either appeared after the curation effort for this organism was carried out or they were inadvertently missed by curators; or that ii) the curation effort for this organism has not yet started.
 
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External resources for this compound

Bibliographic References

No literature references available for this target.

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