Detailed information for compound 973653

Basic information

Technical information
  • Name: Unnamed compound
  • MW: 460.654 | Formula: C29H40N4O
  • H donors: 1 H acceptors: 1 LogP: 4.92 Rotable bonds: 6
    Rule of 5 violations (Lipinski): 1
  • SMILES: CCNCCN1CN(C2(C1=O)CCN(CC2)C1CCC(c2c1cccc2)(C)C)c1ccccc1
  • InChi: 1S/C29H40N4O/c1-4-30-18-21-32-22-33(23-10-6-5-7-11-23)29(27(32)34)16-19-31(20-17-29)26-14-15-28(2,3)25-13-9-8-12-24(25)26/h5-13,26,30H,4,14-22H2,1-3H3
  • InChiKey: SPEMYEUTUHZLSU-UHFFFAOYSA-N  


Substructure search Similarity search

Network

Hover on a compound node to display the structore

Synonyms

No synonyms found for this compound

Targets

Known targets for this compound

Species Target name Source Bibliographic reference
Homo sapiens opioid receptor, mu 1 Starlite/ChEMBL References
Homo sapiens opioid receptor, kappa 1 Starlite/ChEMBL References
Homo sapiens opioid receptor, delta 1 Starlite/ChEMBL References
Homo sapiens opiate receptor-like 1 Starlite/ChEMBL References

Predicted pathogen targets for this compound

By orthology
Species Potential target Known druggable target/s Ortholog Group
Echinococcus multilocularis tm gpcr rhodopsin gpcr rhodopsin superfamily Get druggable targets OG5_139759 All targets in OG5_139759
Echinococcus granulosus tm gpcr rhodopsin Get druggable targets OG5_139759 All targets in OG5_139759
By sequence similarity to non orthologous known druggable targets
Species Potential target Known druggable target Length Alignment span Identity
Echinococcus multilocularis growth hormone secretagogue receptor type 1 opiate receptor-like 1 370 aa 349 aa 22.1 %
Obtained from network model

Ranking Plot

Putative Targets List

Species Potential target Raw Global Species
Brugia malayi jmjC domain containing protein 0.003 0.0029 0.004
Brugia malayi Cathepsin L-like precursor 0.0024 0.0008 0.0012
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0093 0.0257 0.0956
Brugia malayi 60S ribosomal protein L19 0.0028 0.002 0.0027
Schistosoma mansoni tar DNA-binding protein 0.0206 0.0669 0.0876
Echinococcus multilocularis musashi 0.0061 0.0141 0.0185
Echinococcus granulosus cyclin dependent kinase 0.0059 0.0134 0.0175
Echinococcus granulosus casein kinase I alpha 0.0624 0.2187 0.2865
Trichomonas vaginalis CAMK family protein kinase 0.0114 0.0335 0.0763
Trichomonas vaginalis set domain proteins, putative 0.0993 0.3526 0.8217
Entamoeba histolytica Ras family GTPase 0.0061 0.0141 0.031
Echinococcus granulosus 5'partial|histone lysine N methyltransferase SETDB2 0.012 0.0357 0.0468
Trypanosoma cruzi mitochondrial DNA polymerase beta-PAK, putative 0.0152 0.0471 0.1756
Trichomonas vaginalis D-aminoacylase, putative 0.0054 0.0118 0.0255
Echinococcus granulosus sterol regulatory element binding protein 0.0027 0.0017 0.0023
Echinococcus multilocularis chromodomain helicase DNA binding protein 4 0.0032 0.0034 0.0045
Mycobacterium tuberculosis Probable lipase LipE 0.0054 0.0118 0.0328
Loa Loa (eye worm) nuclear hormone receptor family member nhr-40 0.0047 0.009 0.029
Plasmodium falciparum ATP-dependent 6-phosphofructokinase 0.0033 0.0039 0.014
Echinococcus granulosus expressed conserved protein 0.0059 0.0133 0.0174
Trichomonas vaginalis CMGC family protein kinase 0.0059 0.0134 0.0293
Trypanosoma cruzi DNA polymerase kappa, putative 0.0084 0.0225 0.0837
Leishmania major basic transcription factor 3a, putative 0.0034 0.0043 0.0153
Schistosoma mansoni cpg binding protein 0.007 0.0173 0.0226
Toxoplasma gondii cyclin2 related protein 0.003 0.003 0.0107
Echinococcus multilocularis endoplasmin 0.0072 0.0183 0.0239
Trypanosoma brucei PHD-zinc-finger like domain containing protein, putative 0.003 0.0031 0.0109
Trypanosoma cruzi mitochondrial DNA polymerase beta, putative 0.0321 0.1084 0.4052
Loa Loa (eye worm) hypothetical protein 0.0031 0.0034 0.0111
Trypanosoma brucei ATP-dependent 6-phosphofructokinase, glycosomal 0.0121 0.0361 0.1345
Trichomonas vaginalis chromodomain-helicase-DNA-binding protein, putative 0.0034 0.0043 0.008
Schistosoma mansoni serine/threonine protein kinase 0.0143 0.0439 0.0575
Echinococcus multilocularis dna polymerase eta 0.008 0.0212 0.0277
Echinococcus multilocularis Smad4 0.0025 0.0009 0.0012
Mycobacterium tuberculosis Conserved protein 0.0054 0.0118 0.0328
Echinococcus granulosus guanine nucleotide binding protein Gs subunit 0.0093 0.0258 0.0337
Loa Loa (eye worm) beta-LACTamase domain containing family member 0.0054 0.0118 0.038
Echinococcus granulosus cyclin dependent kinase 1 0.0059 0.0134 0.0175
Echinococcus granulosus chromobox protein 1 0.0159 0.0497 0.0652
Loa Loa (eye worm) AGC/GRK/GRK protein kinase 0.0031 0.0031 0.01
Mycobacterium ulcerans fructose-bisphosphate aldolase 0.0588 0.2054 1
Echinococcus multilocularis thyroid hormone receptor alpha 0.0047 0.009 0.0117
Brugia malayi Cathepsin L-like precursor 0.0024 0.0008 0.0012
Echinococcus multilocularis histone lysine N methyltransferase MLL3 0.0024 0.0009 0.0011
Schistosoma mansoni bromodomain-containing nuclear protein 1 brd1 0.0093 0.0259 0.0339
Trypanosoma cruzi polo-like protein kinase, putative 0.0114 0.0335 0.1248
Entamoeba histolytica hypothetical protein 0.0026 0.0014 0.0014
Echinococcus multilocularis casein kinase I alpha 0.0624 0.2187 0.2865
Loa Loa (eye worm) hypothetical protein 0.0054 0.0118 0.038
Echinococcus granulosus Niemann Pick C1 protein 0.0089 0.0244 0.032
Loa Loa (eye worm) hypothetical protein 0.0047 0.009 0.029
Leishmania major hypothetical protein, conserved 0.0054 0.0118 0.0433
Loa Loa (eye worm) MH1 domain-containing protein 0.0025 0.0009 0.003
Schistosoma mansoni acetyl-CoA C-acetyltransferase 0.0025 0.0012 0.0016
Mycobacterium ulcerans acyl-CoA synthetase 0.0051 0.0107 0.024
Brugia malayi Ras-related protein R-Ras2 0.0061 0.0141 0.0195
Schistosoma mansoni tar DNA-binding protein 0.0206 0.0669 0.0876
Onchocerca volvulus 0.0024 0.0008 0.0008
Brugia malayi Associated with TFs and helicases family protein 0.0026 0.0014 0.002
Trichomonas vaginalis GTP-binding protein rit, putative 0.0061 0.0141 0.031
Echinococcus granulosus nuclear receptor 2DBD gamma 0.0047 0.009 0.0117
Echinococcus multilocularis protection of telomeres protein 1 0.0538 0.1873 0.2454
Mycobacterium ulcerans esterase/lipase LipP 0.0054 0.0118 0.0295
Trypanosoma cruzi 60S ribosomal protein L19, putative 0.0028 0.002 0.0068
Echinococcus granulosus lamin dm0 0.0061 0.0141 0.0185
Trypanosoma cruzi major cysteine proteinase, putative 0.0073 0.0185 0.0685
Giardia lamblia Fructose-bisphosphate aldolase 0.1203 0.4289 1
Leishmania major cathepsin L-like protease 0.0024 0.0008 0.0025
Entamoeba histolytica heat shock protein 90, putative 0.0082 0.0219 0.0492
Plasmodium vivax telomerase reverse transcriptase, putative 0.0758 0.2673 1
Leishmania major cathepsin L-like protease 0.0093 0.0257 0.0955
Brugia malayi Fibronectin type III domain containing protein 0.0031 0.0034 0.0047
Leishmania major ATP-dependent phosphofructokinase 0.0121 0.0361 0.1345
Brugia malayi hypothetical protein 0.0428 0.1474 0.2034
Toxoplasma gondii ribosomal protein RPL19 0.0028 0.002 0.0068
Brugia malayi casein kinase I 0.0624 0.2187 0.3018
Loa Loa (eye worm) nuclear hormone receptor-like 1 0.0025 0.001 0.0031
Echinococcus granulosus survival motor neuron protein 1 0.0374 0.128 0.1676
Echinococcus multilocularis chromobox protein 1 0.0159 0.0497 0.0652
Entamoeba histolytica casein kinase 1, putative 0.0624 0.2187 0.509
Loa Loa (eye worm) Papain cysteine protease/cathepsin propeptide inhibitor-containing protein 0.0024 0.0008 0.0027
Loa Loa (eye worm) hypothetical protein 0.0173 0.0549 0.1777
Trichomonas vaginalis chromodomain helicase DNA binding protein, putative 0.0041 0.0067 0.0137
Loa Loa (eye worm) hypothetical protein 0.0036 0.0051 0.0164
Loa Loa (eye worm) hypothetical protein 0.0025 0.001 0.0031
Brugia malayi phosphofructokinase 0.0121 0.0361 0.0498
Mycobacterium tuberculosis Fatty-acid-AMP ligase FadD30 (fatty-acid-AMP synthetase) (fatty-acid-AMP synthase) 0.0038 0.0059 0.0038
Schistosoma mansoni lamin 0.0061 0.0141 0.0185
Giardia lamblia Kinase, CK1 Casein kinase 0.0624 0.2187 0.5077
Echinococcus granulosus Niemann Pick C1 protein 0.0062 0.0147 0.0192
Echinococcus granulosus cytoplasmic intermediate filament protein 0.0029 0.0027 0.0035
Trichomonas vaginalis 60S ribosomal protein L19, putative 0.0028 0.002 0.0027
Trypanosoma cruzi heat shock protein 85, putative 0.0082 0.0219 0.0812
Trichomonas vaginalis heat shock protein, putative 0.0068 0.0168 0.0374
Toxoplasma gondii DNA topoisomerase I, putative 0.02 0.0647 0.2417
Echinococcus multilocularis heat shock protein 0.0082 0.0219 0.0287
Trypanosoma brucei trypanothione reductase 0.004 0.0066 0.024
Loa Loa (eye worm) hypothetical protein 0.0046 0.0086 0.0279
Toxoplasma gondii AGC kinase 0.0046 0.0086 0.0317
Loa Loa (eye worm) jmjC domain-containing protein 0.003 0.0029 0.0095
Trypanosoma cruzi DNA topoisomerase IB, large subunit, putative 0.015 0.0464 0.1732
Brugia malayi AMP-binding enzyme family protein 0.0051 0.0107 0.0147
Leishmania major DNA polymerase eta, putative 0.0042 0.0072 0.0263
Loa Loa (eye worm) cytochrome P450 family protein 0.0042 0.0073 0.0236
Plasmodium vivax endoplasmin, putative 0.0082 0.0219 0.0813
Echinococcus multilocularis chromobox protein 2 0.0026 0.0014 0.0019
Toxoplasma gondii AGC kinase 0.0046 0.0086 0.0317
Leishmania major trypanothione reductase 0.004 0.0066 0.0239
Trypanosoma cruzi casein kinase, delta isoform, putative 0.0615 0.2154 0.8058
Plasmodium falciparum endoplasmin, putative 0.0056 0.0123 0.0454
Loa Loa (eye worm) hypothetical protein 0.0428 0.1474 0.4772
Echinococcus granulosus protection of telomeres protein 1 0.0538 0.1873 0.2454
Echinococcus granulosus casein kinase i 0.0624 0.2187 0.2865
Schistosoma mansoni histone-lysine n-methyltransferase setb1 0.0126 0.0379 0.0496
Loa Loa (eye worm) hypothetical protein 0.0026 0.0014 0.0047
Echinococcus multilocularis guanine nucleotide binding protein G(s) subunit 0.0093 0.0258 0.0337
Schistosoma mansoni cell adhesion molecule 0.0038 0.0059 0.0077
Leishmania major DNA polymerase eta, putative 0.008 0.0212 0.0785
Toxoplasma gondii WD domain, G-beta repeat-containing protein 0.003 0.0031 0.0109
Mycobacterium tuberculosis Conserved protein 0.0054 0.0118 0.0328
Echinococcus multilocularis cathepsin L cysteine protease 0.0024 0.0008 0.0011
Trypanosoma brucei transcription factor BTF3, putative 0.0034 0.0043 0.0153
Loa Loa (eye worm) hypothetical protein 0.0031 0.0034 0.0111
Schistosoma mansoni phosphatidylserine receptor 0.003 0.0029 0.0038
Entamoeba histolytica pyrophosphate-dependent phosphofructokinase 0.0033 0.0039 0.0072
Brugia malayi Nuclear hormone receptor family member nhr-40 0.0047 0.009 0.0124
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0093 0.0257 0.0956
Trypanosoma cruzi ATP-dependent 6-phosphofructokinase, glycosomal 0.0121 0.0361 0.1345
Brugia malayi Protein cec-1. 0.0026 0.0014 0.002
Echinococcus multilocularis jumonji domain containing 1A 0.003 0.0029 0.0038
Echinococcus granulosus tumor protein p63 0.0377 0.1291 0.1691
Loa Loa (eye worm) CHromoDomain protein family member 0.0032 0.0034 0.0111
Leishmania major 60S ribosomal protein L19, putative 0.0028 0.002 0.0068
Toxoplasma gondii histone lysine methyltransferase SET1 0.0128 0.0386 0.1439
Plasmodium falciparum casein kinase 1 0.0624 0.2187 0.8182
Trypanosoma cruzi mitochondrial DNA polymerase beta-PAK, putative 0.0055 0.0119 0.044
Mycobacterium tuberculosis Probable chain -fatty-acid-CoA ligase FadD13 (fatty-acyl-CoA synthetase) 0.0051 0.0107 0.0274
Trichomonas vaginalis ral, putative 0.0061 0.0141 0.031
Echinococcus multilocularis Immunoglobulin 0.0031 0.0034 0.0045
Loa Loa (eye worm) glutamate receptor 0.0034 0.0043 0.0139
Loa Loa (eye worm) hypothetical protein 0.0029 0.0027 0.0086
Trichomonas vaginalis CAMK family protein kinase 0.0114 0.0335 0.0763
Toxoplasma gondii BRCA1 C Terminus (BRCT) domain-containing protein 0.0024 0.0008 0.0025
Leishmania major 60S ribosomal protein L19, putative 0.0028 0.002 0.0068
Schistosoma mansoni hypothetical protein 0.0069 0.0169 0.0221
Plasmodium falciparum cyclin, putative 0.003 0.003 0.0107
Echinococcus granulosus PHD finger protein rhinoceros 0.0093 0.0259 0.0339
Trypanosoma brucei telomerase reverse transcriptase 0.0758 0.2673 1
Trichomonas vaginalis phosphofructokinase, putative 0.0033 0.0039 0.0072
Schistosoma mansoni DNA topoisomerase type I 0.015 0.0464 0.0608
Echinococcus granulosus thioredoxin glutathione reductase 0.0041 0.0068 0.0089
Trichomonas vaginalis AGC family protein kinase 0.0046 0.0086 0.0182
Loa Loa (eye worm) nuclear hormone receptor family member nhr-1 0.0047 0.009 0.029
Schistosoma mansoni chromobox protein 0.0026 0.0014 0.0019
Trypanosoma brucei heat shock protein 90, putative 0.0082 0.0219 0.0813
Entamoeba histolytica phosphofructokinase, putative 0.0121 0.0361 0.0824
Brugia malayi CHD4 protein 0.0032 0.0034 0.0047
Mycobacterium tuberculosis Possible penicillin-binding protein 0.0348 0.1183 0.5647
Schistosoma mansoni jumonji/arid domain-containing protein 0.0118 0.035 0.0458
Brugia malayi MH2 domain containing protein 0.0025 0.0009 0.0013
Loa Loa (eye worm) hypothetical protein 0.0038 0.0059 0.0191
Schistosoma mansoni protein phosphatase 2C 0.003 0.0029 0.0038
Plasmodium vivax 6-phosphofructokinase, putative 0.0033 0.0039 0.014
Brugia malayi jmjC domain containing protein 0.003 0.0029 0.004
Schistosoma mansoni DNA topoisomerase type I 0.015 0.0464 0.0608
Leishmania major cathepsin L-like protease 0.0093 0.0257 0.0955
Trypanosoma brucei heat shock protein, putative 0.0082 0.0219 0.0813
Echinococcus multilocularis jumonji domain containing protein 0.013 0.0391 0.0512
Brugia malayi steroid hormone receptor 0.0047 0.009 0.0124
Trichomonas vaginalis hypothetical protein 0.0026 0.0014 0.0014
Brugia malayi MH2 domain containing protein 0.0025 0.0009 0.0013
Onchocerca volvulus 0.0026 0.0014 0.0014
Schistosoma mansoni cpg binding protein 0.0064 0.0153 0.02
Trypanosoma brucei DNA polymerase kappa, putative 0.0084 0.0225 0.0838
Loa Loa (eye worm) hypothetical protein 0.0031 0.0034 0.0111
Echinococcus granulosus chromodomain helicase DNA binding protein 1 0.0026 0.0014 0.0019
Giardia lamblia Pyrophosphate-fructose 6-phosphate 1-phosphotransferase alpha subunit 0.0033 0.0039 0.0045
Entamoeba histolytica ras-1, putative 0.0061 0.0141 0.031
Toxoplasma gondii 6-phosphofructokinase 0.0033 0.0039 0.014
Trypanosoma brucei DNA polymerase kappa, putative 0.0084 0.0225 0.0838
Trypanosoma brucei mitochondrial DNA polymerase beta 0.0321 0.1084 0.4052
Trypanosoma brucei heat shock protein, putative 0.0082 0.0219 0.0813
Trichomonas vaginalis CAMK family protein kinase 0.0114 0.0335 0.0763
Trichomonas vaginalis CAMK family protein kinase 0.0061 0.0142 0.0311
Chlamydia trachomatis fructose-6-phosphate phosphotransferase 0.0033 0.0039 0.4946
Plasmodium vivax basic transcription factor 3b, putative 0.0034 0.0043 0.0153
Echinococcus multilocularis cysteine protease 0.0024 0.0008 0.0011
Echinococcus granulosus JmjC domain containing protein 4 0.003 0.0029 0.0038
Trichomonas vaginalis CAMK family protein kinase 0.0061 0.0142 0.0311
Brugia malayi Immunoglobulin I-set domain containing protein 0.0136 0.0415 0.0572
Trypanosoma cruzi JmjC domain, hydroxylase, putative 0.003 0.0029 0.0103
Loa Loa (eye worm) AGC/PKA protein kinase 0.0046 0.0086 0.0279
Brugia malayi Niemann-Pick C1 protein precursor 0.0062 0.0147 0.0203
Trichomonas vaginalis conserved hypothetical protein 0.0089 0.0244 0.055
Loa Loa (eye worm) TAR-binding protein 0.0206 0.0669 0.2164
Trypanosoma cruzi casein kinase, putative 0.0624 0.2187 0.8182
Echinococcus granulosus jumonji domain containing protein 0.013 0.0391 0.0512
Echinococcus multilocularis casein kinase I delta 0.0624 0.2187 0.2865
Trypanosoma cruzi DNA polymerase eta, putative 0.008 0.0212 0.0785
Echinococcus multilocularis heat shock protein 90 0.0082 0.0219 0.0287
Echinococcus granulosus Transcription factor JmjC domain containing protein 0.0305 0.1029 0.1348
Trypanosoma cruzi heat shock protein 90, putative 0.0082 0.0219 0.0812
Onchocerca volvulus 0.0134 0.0406 0.0406
Trypanosoma brucei DNA topoisomerase IB, large subunit 0.015 0.0464 0.1733
Loa Loa (eye worm) jmjC domain-containing protein 0.003 0.0029 0.0095
Brugia malayi hypothetical protein 0.0031 0.0034 0.0047
Trypanosoma cruzi heat shock protein 85, putative 0.0082 0.0219 0.0812
Brugia malayi PHD-finger family protein 0.0028 0.0021 0.0028
Mycobacterium leprae Probable fructose bisphosphate aldolase Fba 0.0588 0.2054 1
Loa Loa (eye worm) nuclear Hormone Receptor family member 0.0047 0.009 0.029
Brugia malayi Valyl-tRNA synthetase 0.0026 0.0014 0.002
Trichomonas vaginalis fructose-bisphosphate aldolase, putative 0.1203 0.4289 1
Onchocerca volvulus Huntingtin homolog 0.0247 0.0817 0.0817
Trypanosoma brucei heat shock protein 84, putative 0.0046 0.0087 0.0319
Toxoplasma gondii PHD-finger domain-containing protein 0.003 0.0031 0.0109
Leishmania major cathepsin L-like protease 0.0024 0.0008 0.0025
Echinococcus granulosus ecdysone induced protein 78C 0.0047 0.009 0.0117
Trichomonas vaginalis phosphofructokinase, putative 0.0033 0.0039 0.0072
Chlamydia trachomatis fructose-6-phosphate phosphotransferase 0.0033 0.0039 0.4946
Plasmodium falciparum heterochromatin protein 1 0.0026 0.0014 0.0048
Leishmania major 4-coumarate:coa ligase-like protein 0.0051 0.0107 0.0392
Brugia malayi Ligand-binding domain of nuclear hormone receptor family protein 0.0047 0.009 0.0124
Echinococcus granulosus terminal deoxycytidyl transferase rev1 0.0056 0.0122 0.016
Trypanosoma cruzi Heat shock protein 83, putative 0.0082 0.0219 0.0812
Onchocerca volvulus 0.0024 0.0008 0.0008
Brugia malayi MH1 domain containing protein 0.0025 0.0009 0.0013
Plasmodium falciparum conserved Plasmodium protein, unknown function 0.0026 0.0014 0.0048
Leishmania major protein kinase A catalytic subunit isoform 1 0.0046 0.0086 0.0316
Plasmodium falciparum basic transcription factor 3b, putative 0.0034 0.0043 0.0153
Trypanosoma cruzi cdc2-related kinase 1 0.0059 0.0134 0.0494
Schistosoma mansoni steroid hormone receptor ad4bp 0.0047 0.009 0.0117
Brugia malayi PHD-finger family protein 0.0036 0.0051 0.007
Echinococcus multilocularis histone lysine N methyltransferase SETMAR 0.0126 0.0379 0.0496
Giardia lamblia Heat shock protein HSP 90-alpha 0.0082 0.0219 0.0466
Toxoplasma gondii ImpB/MucB/SamB family protein 0.0042 0.0072 0.0264
Loa Loa (eye worm) hypothetical protein 0.0428 0.1474 0.4772
Leishmania major heat shock protein 83-1 0.0082 0.0219 0.0812
Trypanosoma brucei heat shock protein, putative 0.0082 0.0219 0.0813
Brugia malayi nuclear hormone receptor 0.0047 0.009 0.0124
Echinococcus multilocularis ribosomal protein L19 0.0028 0.002 0.0026
Loa Loa (eye worm) hypothetical protein 0.0051 0.0107 0.0345
Trypanosoma cruzi DNA polymerase eta, putative 0.0042 0.0072 0.0263
Schistosoma mansoni Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) 0.0093 0.0258 0.0337
Schistosoma mansoni heat shock protein 0.0082 0.0219 0.0287
Trypanosoma brucei heat shock protein, putative 0.0082 0.0219 0.0813
Trypanosoma brucei DNA polymerase kappa, putative 0.0045 0.0085 0.0312
Mycobacterium tuberculosis Probable membrane NADH dehydrogenase NdhA 0.0092 0.0253 0.1003
Echinococcus multilocularis cathepsin l cysteine peptidase 0.0024 0.0008 0.0011
Echinococcus multilocularis basement membrane specific heparan sulfate 0.0031 0.0034 0.0045
Onchocerca volvulus Serine\/threonine kinase homolog 0.0114 0.0335 0.0335
Echinococcus granulosus tar DNA binding protein 0.0206 0.0669 0.0876
Schistosoma mansoni chromodomain helicase DNA binding protein 0.0026 0.0014 0.0019
Mycobacterium tuberculosis Probable nitrite reductase [NAD(P)H] large subunit [FAD flavoprotein] NirB 0.0092 0.0253 0.1003
Entamoeba histolytica hypothetical protein 0.0026 0.0014 0.0014
Schistosoma mansoni 6-phosphofructokinase 0.0121 0.0361 0.0473
Loa Loa (eye worm) nucleolar RNA-associated protein alpha 0.024 0.0792 0.2564
Echinococcus multilocularis FTZ F1 nuclear receptor protein 0.0047 0.009 0.0117
Trichomonas vaginalis fructose-bisphosphate aldolase, putative 0.1203 0.4289 1
Schistosoma mansoni hypothetical protein 0.0913 0.3237 0.4239
Mycobacterium ulcerans heat shock protein 90 0.0072 0.0183 0.0622
Toxoplasma gondii phosphofructokinase PFKII 0.0033 0.0039 0.014
Leishmania major lipophosphoglycan biosynthetic protein, putative,heat shock protein 90, putative,glucose regulated protein 94, putative 0.0072 0.0183 0.0678
Echinococcus multilocularis COUP TF:Svp nuclear hormone receptor 0.0047 0.009 0.0117
Echinococcus multilocularis serine:threonine protein kinase PLK1 0.0114 0.0335 0.0439
Echinococcus granulosus tm gpcr rhodopsin 0.0642 0.2253 0.2951
Echinococcus granulosus cyclin dependent kinase 5 0.0059 0.0134 0.0175
Trichomonas vaginalis chromobox protein, putative 0.0096 0.0268 0.0607
Loa Loa (eye worm) latrophilin receptor protein 2 0.0069 0.0169 0.0546
Mycobacterium tuberculosis Conserved hypothetical protein 0.0169 0.0533 0.2404
Onchocerca volvulus Steroid hormone receptor family member cnr14 homolog 0.0047 0.009 0.009
Loa Loa (eye worm) Ras protein let-60 0.0061 0.0141 0.0457
Brugia malayi Latrophilin receptor protein 2 0.0069 0.0169 0.0233
Giardia lamblia DINP protein human, muc B family 0.0063 0.0148 0.03
Brugia malayi beta-NAC-like protein 0.0034 0.0043 0.0059
Loa Loa (eye worm) heat shock protein 75 0.0046 0.0087 0.0281
Mycobacterium ulcerans hypothetical protein 0.0169 0.0533 0.2377
Loa Loa (eye worm) fibroinase 0.0024 0.0008 0.0027
Brugia malayi Probable G protein-coupled receptor kinase F19C6.1, putative 0.0031 0.0031 0.0043
Loa Loa (eye worm) hypothetical protein 0.0026 0.0014 0.0047
Echinococcus multilocularis Nuclear hormone receptor family member nhr 41 0.0047 0.009 0.0117
Trypanosoma brucei DNA polymerase kappa, putative 0.0045 0.0085 0.0312
Brugia malayi Nuclear hormone receptor family member nhr-3 0.0047 0.009 0.0124
Brugia malayi Pre-SET motif family protein 0.0872 0.3089 0.4263
Trypanosoma cruzi JmjC domain, hydroxylase, putative 0.003 0.0029 0.0103
Echinococcus granulosus tyrosyl DNA phosphodiesterase 1 0.0069 0.0172 0.0225
Trypanosoma brucei cyclin 2 0.003 0.003 0.0107
Echinococcus granulosus heat shock protein 90 0.0082 0.0219 0.0287
Leishmania major protein kinase, putative,polo-like protein kinase, putative 0.0114 0.0335 0.1248
Loa Loa (eye worm) hypothetical protein 0.0038 0.0059 0.0192
Leishmania major protein kinase A catalytic subunit 0.0046 0.0086 0.0316
Leishmania major telomerase reverse transcriptase, putative 0.0758 0.2673 1
Echinococcus multilocularis casein kinase I alpha 0.0624 0.2187 0.2865
Schistosoma mansoni aldehyde dehydrogenase 0.0047 0.0092 0.012
Trichomonas vaginalis chromodomain-helicase-DNA-binding protein, putative 0.0041 0.0067 0.0137
Trypanosoma cruzi 60S ribosomal protein L19, putative 0.0028 0.002 0.0068
Echinococcus granulosus expressed protein 0.0417 0.1434 0.1879
Trypanosoma brucei DNA polymerase kappa, putative 0.0046 0.0086 0.0316
Trypanosoma brucei heat shock protein, putative 0.0082 0.0219 0.0813
Trichomonas vaginalis penicillin-binding protein, putative 0.0054 0.0118 0.0255
Onchocerca volvulus 0.007 0.0174 0.0174
Plasmodium falciparum cAMP-dependent protein kinase catalytic subunit 0.0046 0.0086 0.0317
Echinococcus granulosus histone lysine N methyltransferase MLL3 0.0024 0.0009 0.0011
Trichomonas vaginalis esterase, putative 0.0054 0.0118 0.0255
Loa Loa (eye worm) hypothetical protein 0.0046 0.0086 0.0278
Schistosoma mansoni protein kinase 0.0624 0.2187 0.2865
Schistosoma mansoni thyroid hormone receptor 0.0047 0.009 0.0117
Trypanosoma cruzi hypothetical protein, conserved 0.0054 0.0118 0.0433
Trichomonas vaginalis conserved hypothetical protein 0.0034 0.0043 0.008
Brugia malayi hypothetical protein 0.0025 0.001 0.0013
Schistosoma mansoni hypothetical protein 0.0069 0.0169 0.0221
Echinococcus granulosus heat shock protein heat shock protein 90 alpha 0.0068 0.0168 0.022
Toxoplasma gondii ABC1 family protein 0.0054 0.0118 0.0434
Trichomonas vaginalis CAMK family protein kinase 0.0114 0.0335 0.0763
Brugia malayi hypoxia-induced factor 1 0.016 0.05 0.069
Mycobacterium tuberculosis Possible conserved lipoprotein LpqK 0.0054 0.0118 0.0328
Trichomonas vaginalis phosphofructokinase, putative 0.0033 0.0039 0.0072
Mycobacterium ulcerans hypothetical protein 0.0054 0.0118 0.0295
Echinococcus granulosus heat shock protein 0.0082 0.0219 0.0287
Entamoeba histolytica fructose-1,6-bisphosphate aldolase, putative 0.1203 0.4289 1
Loa Loa (eye worm) 6-phosphofructokinase 0.0121 0.0361 0.1168
Brugia malayi Nuclear hormone receptor-like 1 0.0025 0.001 0.0013
Trypanosoma cruzi DNA polymerase kappa, putative 0.0084 0.0225 0.0837
Trypanosoma brucei polo-like protein kinase 0.0114 0.0335 0.1248
Brugia malayi PAS domain containing protein 0.0052 0.0107 0.0148
Schistosoma mansoni serine/threonine protein kinase 0.0046 0.0086 0.0113
Plasmodium vivax thioredoxin reductase, putative 0.004 0.0066 0.024
Brugia malayi Importin beta-1 subunit 0.0022 0.0002 0.0002
Trypanosoma brucei DNA polymerase IV, putative 0.0084 0.0225 0.0838
Schistosoma mansoni family S12 unassigned peptidase (S12 family) 0.0054 0.0118 0.0154
Echinococcus granulosus endoplasmin 0.0072 0.0183 0.0239
Entamoeba histolytica cell division protein kinase 2, putative 0.0059 0.0134 0.0293
Plasmodium falciparum telomerase reverse transcriptase 0.0758 0.2673 1
Loa Loa (eye worm) beta-lactamase 0.0054 0.0118 0.038
Plasmodium vivax protein kinase Crk2 0.0059 0.0134 0.0495
Loa Loa (eye worm) heat shock protein 90 0.0082 0.0219 0.0708
Entamoeba histolytica hypothetical protein 0.0083 0.0222 0.0498
Trypanosoma cruzi cysteine peptidase, putative 0.0093 0.0257 0.0955
Onchocerca volvulus 0.0615 0.2154 0.2154
Mycobacterium tuberculosis Probable conserved lipoprotein 0.0054 0.0118 0.0328
Trichomonas vaginalis conserved hypothetical protein 0.0063 0.0149 0.0329
Trichomonas vaginalis CK1 family protein kinase 0.0624 0.2187 0.509
Loa Loa (eye worm) hypothetical protein 0.0026 0.0014 0.0047
Brugia malayi nuclear receptor NHR-88 0.0047 0.009 0.0124
Trichomonas vaginalis conserved hypothetical protein 0.0026 0.0014 0.0014
Brugia malayi CHE-14 protein 0.0027 0.0017 0.0024
Schistosoma mansoni jumonji/arid domain-containing protein 0.0118 0.035 0.0458
Trypanosoma brucei CYC2-like cyclin, putative 0.003 0.003 0.0107
Brugia malayi Cytochrome P450 family protein 0.0042 0.0073 0.0101
Leishmania major heat shock protein 83-1 0.0082 0.0219 0.0812
Schistosoma mansoni histone-lysine n-methyltransferase suv9 0.0152 0.0473 0.062
Leishmania major heat shock protein 83-1 0.0082 0.0219 0.0812
Trypanosoma brucei PHD-zinc-finger like domain containing protein, putative 0.003 0.0031 0.0109
Schistosoma mansoni importin beta-1 0.0022 0.0002 0.0002
Brugia malayi GTP-binding regulatory protein Gs alpha-S chain, putative 0.0093 0.0258 0.0355
Echinococcus granulosus bromodomain adjacent to zinc finger domain 0.0061 0.0143 0.0187
Schistosoma mansoni metabotropic glutamate receptor 2 3 (mglur group 2) 0.0039 0.006 0.0078
Brugia malayi hypothetical protein 0.0106 0.0305 0.0422
Echinococcus multilocularis bromodomain adjacent to zinc finger domain 0.0035 0.0046 0.006
Trypanosoma brucei cdc2-related kinase 3 0.0059 0.0134 0.0495
Brugia malayi Tyrosyl-DNA phosphodiesterase family protein 0.0069 0.0172 0.0237
Echinococcus multilocularis neuroglian 0.0035 0.0046 0.0061
Echinococcus granulosus chromobox protein 1 0.0159 0.0497 0.0652
Schistosoma mansoni patched 1 0.0027 0.0017 0.0023
Entamoeba histolytica Ras family GTPase 0.0061 0.0141 0.031
Giardia lamblia Telomerase catalytic subunit 0.0758 0.2673 0.6214
Schistosoma mansoni nuclear receptor 2DBD-gamma 0.0047 0.009 0.0117
Echinococcus granulosus cathepsin L cysteine proteinase 0.0024 0.0008 0.0011
Entamoeba histolytica PH domain containing protein kinase, putative 0.0046 0.0086 0.0182
Echinococcus multilocularis transcription factor Dp 1 0.004 0.0066 0.0086
Echinococcus multilocularis GPCR, family 2 0.0069 0.0169 0.0221
Echinococcus granulosus lysine specific demethylase 5A 0.0118 0.035 0.0458
Leishmania major cathepsin L-like protease 0.0093 0.0257 0.0955
Trichomonas vaginalis chromodomain-helicase-DNA-binding protein, putative 0.0026 0.0014 0.0014
Schistosoma mansoni zinc finger protein 0.0023 0.0002 0.0002
Loa Loa (eye worm) hypothetical protein 0.0068 0.0168 0.0544
Plasmodium falciparum ATP-dependent 6-phosphofructokinase 0.0033 0.0039 0.014
Brugia malayi hypothetical protein 0.0247 0.0817 0.1128
Plasmodium vivax heat shock protein, putative 0.0196 0.0633 0.2365
Loa Loa (eye worm) MH2 domain-containing protein 0.0025 0.0009 0.003
Trypanosoma cruzi cdc2-related kinase 3 0.0059 0.0134 0.0494
Echinococcus multilocularis cathepsin L cysteine protease 0.0024 0.0008 0.0011
Loa Loa (eye worm) RNA binding protein 0.0206 0.0669 0.2164
Brugia malayi Steroid receptor seven-up type 2 0.0047 0.009 0.0124
Brugia malayi hypothetical protein 0.0106 0.0305 0.0422
Echinococcus multilocularis importin subunit beta 1 0.0022 0.0002 0.0002
Giardia lamblia Kinase, PLK 0.0114 0.0335 0.0738
Trypanosoma brucei heat shock protein, putative 0.0082 0.0219 0.0813
Loa Loa (eye worm) hypothetical protein 0.0039 0.0063 0.0203
Trichomonas vaginalis chromodomain helicase DNA binding protein, putative 0.0041 0.0067 0.0137
Leishmania major DNA topoisomerase type IB small subunit 0.005 0.0103 0.0378
Mycobacterium ulcerans fusion of enoyl-CoA hydratase, EchA21 and lipase, LipE 0.0054 0.0118 0.0295
Schistosoma mansoni rab geranylgeranyl transferase alpha subunit 0.0056 0.0122 0.016
Trypanosoma brucei DNA polymerase kappa, putative 0.0084 0.0225 0.0838
Trichomonas vaginalis conserved hypothetical protein 0.0026 0.0014 0.0014
Entamoeba histolytica phosphofructokinase, putative 0.0121 0.0361 0.0824
Loa Loa (eye worm) hypothetical protein 0.0038 0.0059 0.0192
Plasmodium falciparum conserved Plasmodium membrane protein, unknown function 0.0034 0.0045 0.0162
Schistosoma mansoni microtubule-associated protein tau 0.2124 0.7635 1
Plasmodium vivax hypothetical protein, conserved 0.0034 0.0045 0.0162
Trichomonas vaginalis phosphofructokinase, putative 0.0121 0.0361 0.0824
Echinococcus granulosus transcription factor btf3 0.0034 0.0043 0.0056
Brugia malayi Hsp90 protein 0.0046 0.0087 0.012
Loa Loa (eye worm) pre-SET domain-containing protein family protein 0.0872 0.3089 1
Schistosoma mansoni hypothetical protein 0.0026 0.0014 0.0018
Plasmodium vivax vivapain-2 0.0024 0.0008 0.0025
Brugia malayi Ras protein let-60 0.0061 0.0141 0.0195
Schistosoma mansoni cellular tumor antigen P53 0.0055 0.0121 0.0158
Brugia malayi mbt repeat family protein 0.005 0.0102 0.0141
Brugia malayi Smad1 0.0025 0.0009 0.0013
Echinococcus multilocularis Protein lozenge 0.0054 0.0115 0.015
Brugia malayi DNA topoisomerase I 0.02 0.0647 0.0893
Plasmodium vivax heterochromatin protein 1, putative 0.0026 0.0014 0.0048
Trypanosoma cruzi casein kinase, delta isoform, putative 0.0624 0.2187 0.8182
Loa Loa (eye worm) MH2 domain-containing protein 0.0362 0.1233 0.3993
Echinococcus multilocularis casein kinase I alpha 0.0624 0.2187 0.2865
Mycobacterium ulcerans acyl-CoA synthetase 0.0051 0.0107 0.024
Loa Loa (eye worm) hypothetical protein 0.0028 0.0023 0.0073
Trichomonas vaginalis CK1 family protein kinase 0.0624 0.2187 0.509
Plasmodium vivax cyclin, putative 0.003 0.003 0.0107
Onchocerca volvulus 0.0024 0.0008 0.0008
Leishmania major aldehyde dehydrogenase, mitochondrial precursor 0.0047 0.0092 0.0337
Echinococcus granulosus roundabout 2 0.0042 0.0071 0.0093
Loa Loa (eye worm) hypothetical protein 0.0106 0.0305 0.0989
Mycobacterium ulcerans DNA polymerase IV 0.0084 0.0225 0.0836
Loa Loa (eye worm) CK1/CK1/CK1-D protein kinase 0.0624 0.2187 0.7081
Plasmodium vivax hypothetical protein, conserved 0.0093 0.0259 0.0962
Brugia malayi Bromodomain containing protein 0.0096 0.0267 0.0368
Echinococcus granulosus Basic leucine zipper bZIP transcription 0.0083 0.0222 0.029
Leishmania major cell division protein kinase 2,cdc2-related kinase 0.0059 0.0134 0.0494
Loa Loa (eye worm) nuclear hormone receptor family member nhr-31 0.0047 0.009 0.029
Trichomonas vaginalis phosphofructokinase, putative 0.0033 0.0039 0.0072
Plasmodium falciparum phd finger protein, putative 0.0093 0.0259 0.0962
Plasmodium falciparum cysteine proteinase falcipain 3 0.0024 0.0008 0.0025
Leishmania major heat shock protein, putative 0.0046 0.0087 0.0319
Schistosoma mansoni endoplasmin 0.0082 0.0219 0.0287
Giardia lamblia Kinase, CMGC CDK 0.0059 0.0134 0.0267
Echinococcus multilocularis transfer RNA-Lys 0.0038 0.0059 0.0077
Brugia malayi jmjC domain containing protein 0.0305 0.1029 0.142
Echinococcus multilocularis cAMP dependent protein kinase catalytic subunit 0.0046 0.0086 0.0113
Schistosoma mansoni serine/threonine protein kinase 0.0031 0.0031 0.004
Trypanosoma cruzi heat shock protein 85, putative 0.0068 0.0168 0.0623
Trypanosoma cruzi telomerase reverse transcriptase, putative 0.0758 0.2673 1
Trichomonas vaginalis fructose-bisphosphate aldolase, putative 0.1203 0.4289 1
Trypanosoma brucei DNA polymerase eta, putative 0.008 0.0212 0.0786
Treponema pallidum diphosphate--fructose-6-phosphate 1-phosphotransferase 0.0121 0.0361 0.0757
Echinococcus granulosus polycomb protein SCMH1 0.005 0.0102 0.0134
Schistosoma mansoni tar DNA-binding protein 0.0206 0.0669 0.0876
Brugia malayi Calcitonin receptor-like protein seb-1 0.0217 0.0706 0.0975
Brugia malayi Immunoglobulin I-set domain containing protein 0.0031 0.0034 0.0047
Mycobacterium tuberculosis NAD(P)H quinone reductase LpdA 0.0102 0.029 0.1188
Loa Loa (eye worm) hypothetical protein 0.005 0.0102 0.033
Trichomonas vaginalis chromodomain helicase DNA binding protein, putative 0.0033 0.0039 0.0071
Trichomonas vaginalis phosphofructokinase, putative 0.0121 0.0361 0.0824
Brugia malayi hypothetical protein 0.0374 0.128 0.1766
Loa Loa (eye worm) hypothetical protein 0.016 0.05 0.162
Toxoplasma gondii cathepsin CPL 0.0024 0.0008 0.0025
Mycobacterium tuberculosis Conserved protein 0.0054 0.0118 0.0328
Loa Loa (eye worm) intermediate filament protein 0.0061 0.0141 0.0457
Trypanosoma cruzi heat shock protein 90, putative 0.004 0.0066 0.0242
Trypanosoma cruzi heat shock protein, putative 0.0046 0.0087 0.0319
Loa Loa (eye worm) hypothetical protein 0.0026 0.0014 0.0047
Brugia malayi hypothetical protein 0.0173 0.0549 0.0758
Plasmodium vivax acyl-CoA synthetase, putative 0.0038 0.0059 0.0216
Schistosoma mansoni hypothetical protein 0.003 0.0031 0.004
Treponema pallidum heat shock protein 90 0.0072 0.0183 0.0338
Brugia malayi intermediate filament protein 0.0061 0.0141 0.0195
Echinococcus granulosus ras gtpase 0.0061 0.0141 0.0185
Brugia malayi ecdysteroid receptor 0.0047 0.009 0.0124
Echinococcus granulosus bromodomain adjacent to zinc finger domain 0.0035 0.0046 0.006
Onchocerca volvulus Tyrosine kinase homolog 0.0101 0.0287 0.0287
Loa Loa (eye worm) hypothetical protein 0.0093 0.0259 0.0837
Schistosoma mansoni hypothetical protein 0.0106 0.0305 0.04
Brugia malayi M-phase phosphoprotein, mpp8 0.0026 0.0014 0.002
Trypanosoma cruzi tyrosyl-DNA Phosphodiesterase (Tdp1), putative 0.0069 0.0172 0.0637
Leishmania major heat shock protein 83-1 0.0082 0.0219 0.0812
Schistosoma mansoni chromodomain helicase DNA binding protein 0.0032 0.0034 0.0045
Echinococcus granulosus jumonji domain containing 1A 0.003 0.0029 0.0038
Brugia malayi AMP-binding enzyme family protein 0.0051 0.0107 0.0147
Brugia malayi Nuclear hormone receptor family member nhr-25 0.0047 0.009 0.0124
Leishmania major cathepsin L-like protease 0.0024 0.0008 0.0025
Trypanosoma brucei cAMP-dependent protein kinase catalytic subunit 2 0.0046 0.0086 0.0317
Trichomonas vaginalis chromodomain-helicase-DNA-binding protein, putative 0.0041 0.0067 0.0137
Plasmodium vivax glutathione reductase, putative 0.004 0.0066 0.024
Loa Loa (eye worm) hypothetical protein 0.0033 0.0039 0.0127
Trypanosoma cruzi transcription factor btf3, putative 0.0034 0.0043 0.0153
Mycobacterium tuberculosis Probable lipase LipD 0.0054 0.0118 0.0328
Echinococcus granulosus diuretic hormone 44 receptor GPRdih2 0.0069 0.0169 0.0221
Echinococcus multilocularis heat shock protein 75 kDa, mitochondrial 0.0046 0.0087 0.0114
Echinococcus granulosus cathepsin l1 0.0024 0.0008 0.0011
Brugia malayi Nuclear hormone receptor family member nhr-31 0.0047 0.009 0.0124
Echinococcus multilocularis smad 0.0025 0.0009 0.0012
Schistosoma mansoni tyrosyl-DNA phosphodiesterase 0.0069 0.0172 0.0225
Schistosoma mansoni tar DNA-binding protein 0.0206 0.0669 0.0876
Loa Loa (eye worm) RNA recognition domain-containing protein domain-containing protein 0.0206 0.0669 0.2164
Schistosoma mansoni Tr4/Tr2 (homologue) 0.0047 0.009 0.0117
Schistosoma mansoni 60S ribosomal protein L19 0.0028 0.002 0.0026
Brugia malayi Heterochromatin protein 1 0.0159 0.0497 0.0687
Schistosoma mansoni serine/threonine protein kinase 0.0031 0.0031 0.004
Echinococcus multilocularis lamin 0.0061 0.0141 0.0185
Echinococcus multilocularis metabotropic glutamate receptor 5 0.0042 0.0071 0.0093
Toxoplasma gondii Hsp90 domain-containing protein 0.0196 0.0633 0.2365
Brugia malayi Iron-sulfur cluster assembly accessory protein 0.0076 0.0197 0.0272
Trichomonas vaginalis 6-phosphofructokinase, putative 0.0033 0.0039 0.0072
Mycobacterium tuberculosis Dihydrolipoamide dehydrogenase LpdC (lipoamide reductase (NADH)) (lipoyl dehydrogenase) (dihydrolipoyl dehydrogenase) (diaphoras 0.0102 0.029 0.1188
Loa Loa (eye worm) TK/KIN16 protein kinase 0.0136 0.0415 0.1342
Entamoeba histolytica heat shock protein 90, putative 0.0082 0.0219 0.0492
Leishmania major heat shock protein 83-1 0.0082 0.0219 0.0812
Brugia malayi RNA, U transporter 1 0.0064 0.0152 0.021
Loa Loa (eye worm) hypothetical protein 0.0025 0.001 0.0031
Echinococcus granulosus zinc finger protein 0.0023 0.0002 0.0002
Echinococcus granulosus cAMP dependent protein kinase catalytic subunit 0.0046 0.0086 0.0113
Loa Loa (eye worm) endoplasmin 0.0082 0.0219 0.0708
Trichomonas vaginalis conserved hypothetical protein 0.0034 0.0043 0.008
Loa Loa (eye worm) hypothetical protein 0.0042 0.0071 0.0229
Trypanosoma brucei Heat shock protein 83, putative 0.0082 0.0219 0.0813
Trypanosoma brucei DNA polymerase kappa, putative 0.0084 0.0225 0.0838
Echinococcus multilocularis expressed conserved protein 0.0059 0.0133 0.0174
Trypanosoma cruzi casein kinase, putative 0.0624 0.2187 0.8182
Echinococcus granulosus geminin 0.0278 0.093 0.1219
Loa Loa (eye worm) AGC/DMPK/ROCK protein kinase 0.0426 0.1466 0.4746
Trichomonas vaginalis heat shock protein, putative 0.0072 0.0183 0.0407
Loa Loa (eye worm) pigment dispersing factor receptor c 0.0217 0.0706 0.2287
Trichomonas vaginalis CAMK family protein kinase 0.0114 0.0335 0.0763
Trichomonas vaginalis conserved hypothetical protein 0.0026 0.0014 0.0014
Trypanosoma brucei cAMP-dependent protein kinase catalytic subunit 1 0.0046 0.0086 0.0317
Echinococcus granulosus cAMP dependent protein kinase catalytic subunit 0.0046 0.0086 0.0113
Trichomonas vaginalis DNA polymerase IV / kappa, putative 0.0084 0.0225 0.0507
Trypanosoma brucei DNA polymerase beta thumb, putative 0.0045 0.0084 0.0307
Schistosoma mansoni aldehyde dehydrogenase 0.0047 0.0092 0.012
Loa Loa (eye worm) hypothetical protein 0.008 0.0212 0.0685
Mycobacterium ulcerans aldehyde dehydrogenase 0.0047 0.0092 0.0167
Toxoplasma gondii protein kinase, cAMP-dependent, catalytic chain 0.0046 0.0086 0.0317
Trypanosoma brucei DNA polymerase kappa, putative 0.0046 0.0086 0.0316
Echinococcus multilocularis microtubule associated protein 2 0.2124 0.7635 1
Echinococcus multilocularis cAMP dependent protein kinase catalytic subunit 0.0046 0.0086 0.0113
Schistosoma mansoni hypothetical protein 0.0308 0.1038 0.1359
Plasmodium vivax heat shock protein 86, putative 0.0082 0.0219 0.0813
Trypanosoma brucei JmjC domain, hydroxylase, putative 0.003 0.0029 0.0103
Schistosoma mansoni heat shock protein 0.0046 0.0087 0.0114
Brugia malayi jmjC domain containing protein 0.003 0.0029 0.004
Leishmania major cathepsin L-like protease 0.0024 0.0008 0.0025
Echinococcus granulosus smad 0.0025 0.0009 0.0012
Schistosoma mansoni smad1 5 8 and 0.0025 0.0009 0.0012
Schistosoma mansoni Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) 0.0093 0.0258 0.0337
Schistosoma mansoni cpg binding protein 0.007 0.0173 0.0226
Trichomonas vaginalis D-aminoacylase, putative 0.0054 0.0118 0.0255
Trypanosoma cruzi CYC2-like cyclin 4, putative 0.003 0.003 0.0106
Mycobacterium tuberculosis Probable fatty-acid-CoA ligase FadD2 (fatty-acid-CoA synthetase) (fatty-acid-CoA synthase) 0.0051 0.0107 0.0274
Plasmodium vivax cAMP-dependent protein kinase catalytic subunit, putative 0.0046 0.0086 0.0317
Echinococcus granulosus transcription factor Dp 1 0.004 0.0066 0.0086
Mycobacterium leprae Probable lipase LipE 0.0054 0.0118 0.0056
Loa Loa (eye worm) 6-phosphofructokinase 0.0121 0.0361 0.1168
Plasmodium vivax 60S ribosomal protein L19, putative 0.0028 0.002 0.0068
Echinococcus multilocularis histone lysine methyltransferase setb histone lysine methyltransferase eggless 0.0143 0.0439 0.0575
Plasmodium falciparum 60S ribosomal protein L19 0.0028 0.002 0.0068
Plasmodium falciparum topoisomerase I 0.02 0.0647 0.2417
Schistosoma mansoni niemann-pick C1 (NPC1) 0.0063 0.015 0.0197
Echinococcus multilocularis heat shock protein 90 0.0068 0.0168 0.022
Entamoeba histolytica acyl-coA synthetase, putative 0.0051 0.0107 0.0229
Schistosoma mansoni Neurotrimin precursor (hNT) 0.0031 0.0034 0.0045
Schistosoma mansoni chromobox protein 0.0159 0.0497 0.0652
Brugia malayi Nuclear hormone receptor-like 1 0.0047 0.009 0.0124
Trichomonas vaginalis endoplasmin, putative 0.0056 0.0123 0.0268
Schistosoma mansoni terminal deoxycytidyl transferase 0.0056 0.0122 0.016
Schistosoma mansoni histone-lysine n-methyltransferase setb1 0.0143 0.0439 0.0575
Mycobacterium ulcerans aldehyde dehydrogenase 0.0047 0.0092 0.0167
Echinococcus multilocularis hepatocyte nuclear factor 4 alpha 0.0047 0.009 0.0117
Echinococcus granulosus heat shock protein 90 0.0068 0.0168 0.022
Echinococcus multilocularis Niemann Pick C1 protein 0.0089 0.0244 0.032
Echinococcus multilocularis tumor protein p63 0.0377 0.1291 0.1691
Trypanosoma cruzi casein kinase, putative 0.0624 0.2187 0.8182
Echinococcus multilocularis bromodomain adjacent to zinc finger domain 0.0061 0.0143 0.0187
Mycobacterium tuberculosis Possible DNA-damage-inducible protein P DinP (DNA polymerase V) (pol IV 2) (DNA nucleotidyltransferase (DNA-directed)) 0.0063 0.0148 0.0479
Echinococcus granulosus snurportin 1 0.024 0.0792 0.1037
Schistosoma mansoni aryl hydrocarbon receptor 0.0052 0.0107 0.0141
Loa Loa (eye worm) jmjC domain-containing protein 0.0192 0.0619 0.2004
Entamoeba histolytica cell division protein kinase 2, putative 0.0059 0.0134 0.0293
Brugia malayi MH2 domain containing protein 0.0362 0.1233 0.1702
Leishmania major heat shock protein 83-1 0.0082 0.0219 0.0812
Loa Loa (eye worm) steroid hormone receptor 0.0047 0.009 0.029
Loa Loa (eye worm) hypothetical protein 0.0026 0.0014 0.0047
Echinococcus granulosus dna polymerase kappa 0.0084 0.0225 0.0295
Echinococcus multilocularis arachidonate 5 lipoxygenase 0.0078 0.0202 0.0265
Echinococcus multilocularis tyrosyl DNA phosphodiesterase 1 0.0069 0.0172 0.0225
Mycobacterium tuberculosis NADPH-dependent mycothiol reductase Mtr 0.004 0.0066 0.007
Loa Loa (eye worm) hypothetical protein 0.0047 0.009 0.029
Trichomonas vaginalis heat shock protein, putative 0.0072 0.0183 0.0407
Trypanosoma cruzi heat shock protein 90, putative 0.0068 0.0168 0.0623
Trypanosoma brucei DNA polymerase kappa, putative 0.0063 0.0148 0.0547
Mycobacterium ulcerans long-chain-fatty-acid-CoA ligase 0.0051 0.0107 0.024
Echinococcus multilocularis thioredoxin glutathione reductase 0.0041 0.0068 0.0089
Loa Loa (eye worm) GTP-binding regulatory protein Gs alpha-S chain 0.0093 0.0258 0.0834
Echinococcus multilocularis cyclin dependent kinase 1 0.0059 0.0134 0.0175
Echinococcus multilocularis histone acetyltransferase MYST2 0.0057 0.0127 0.0167
Trypanosoma brucei DNA polymerase kappa, putative 0.0084 0.0225 0.0838
Echinococcus multilocularis cadherin EGF LAG seven pass G type receptor 0.0069 0.0169 0.0221
Echinococcus multilocularis lamin dm0 0.0061 0.0141 0.0185
Loa Loa (eye worm) hypothetical protein 0.0047 0.009 0.029
Trypanosoma cruzi transcription factor btf3, putative 0.0034 0.0043 0.0153
Plasmodium falciparum heat shock protein 90, putative 0.0042 0.0072 0.0265
Trypanosoma cruzi trypanothione reductase, putative 0.004 0.0066 0.0239
Brugia malayi hypothetical protein 0.0083 0.0222 0.0306
Mycobacterium ulcerans long-chain fatty-acid CoA ligase 0.0051 0.0107 0.024
Brugia malayi jmjC domain containing protein 0.0118 0.035 0.0483
Leishmania major mitochondrial DNA polymerase beta-PAK, putative 0.0152 0.0471 0.1756
Leishmania major cell division related protein kinase 2,cdc2-related kinase 0.0059 0.0134 0.0494
Echinococcus granulosus neuropeptide s receptor 0.1131 0.4029 0.5277
Loa Loa (eye worm) hypothetical protein 0.0031 0.0034 0.0111
Brugia malayi F/Y-rich N-terminus family protein 0.0056 0.0125 0.0173
Schistosoma mansoni mixed-lineage leukemia protein mll 0.0141 0.0431 0.0564
Loa Loa (eye worm) hypothetical protein 0.0054 0.0118 0.038
Schistosoma mansoni serine/threonine protein kinase 0.0059 0.0134 0.0175
Mycobacterium tuberculosis Conserved hypothetical protein 0.0056 0.0122 0.0351
Trichomonas vaginalis chromodomain helicase DNA binding protein, putative 0.0041 0.0067 0.0137
Loa Loa (eye worm) PHD-finger family protein 0.0093 0.0259 0.0837
Plasmodium vivax hypothetical protein, conserved 0.0026 0.0014 0.0048
Loa Loa (eye worm) transcription factor SMAD2 0.0362 0.1233 0.3993
Trichomonas vaginalis conserved hypothetical protein 0.0063 0.0149 0.0329
Trichomonas vaginalis fructose-bisphosphate aldolase, putative 0.1203 0.4289 1
Schistosoma mansoni serine/threonine protein kinase 0.0114 0.0335 0.0439
Leishmania major heat shock protein 83-1 0.0082 0.0219 0.0812
Loa Loa (eye worm) hypothetical protein 0.0061 0.0141 0.0457
Echinococcus granulosus metabotropic glutamate receptor 5 0.0042 0.0071 0.0093
Trichomonas vaginalis heat shock protein, putative 0.0042 0.0072 0.015
Echinococcus granulosus Protein patched homolog 1 0.0027 0.0017 0.0023
Trypanosoma brucei hypothetical protein, conserved 0.0054 0.0118 0.0434
Schistosoma mansoni retinoic acid receptor RXR 0.0047 0.009 0.0117
Echinococcus granulosus intermediate filament protein 0.0061 0.0141 0.0185
Trichomonas vaginalis rap1 and, putative 0.0061 0.0141 0.031
Schistosoma mansoni nuclear hormone receptor nor-1/nor-2 0.0047 0.009 0.0117
Echinococcus granulosus casein kinase I delta 0.0624 0.2187 0.2865
Loa Loa (eye worm) DNA topoisomerase I 0.02 0.0647 0.2095
Mycobacterium leprae PROBABLE 6-PHOSPHOFRUCTOKINASE PFKA (PHOSPHOHEXOKINASE) (PHOSPHOFRUCTOKINASE) 0.0121 0.0361 0.1306
Trichomonas vaginalis phosphofructokinase, putative 0.0033 0.0039 0.0072
Echinococcus multilocularis survival motor neuron protein 1 0.0374 0.128 0.1676
Onchocerca volvulus 0.0054 0.0118 0.0118
Schistosoma mansoni hypothetical protein 0.0069 0.0169 0.0221
Onchocerca volvulus 0.0038 0.0059 0.0059
Echinococcus granulosus fetal alzheimer antigen falz 0.0025 0.0012 0.0016
Echinococcus granulosus casein kinase I alpha 0.0624 0.2187 0.2865
Trichomonas vaginalis conserved hypothetical protein 0.0089 0.0244 0.055
Echinococcus multilocularis cyclin dependent kinase 1 0.0059 0.0134 0.0175
Trichomonas vaginalis chromobox protein, putative 0.0026 0.0014 0.0014
Trichomonas vaginalis fructose-bisphosphate aldolase, putative 0.1203 0.4289 1
Entamoeba histolytica transcription factor BTF3, putative 0.0034 0.0043 0.008
Mycobacterium ulcerans aldehyde dehydrogenase 0.0047 0.0092 0.0167
Echinococcus multilocularis zinc finger protein 0.0023 0.0002 0.0002
Mycobacterium ulcerans 6-phosphofructokinase 0.0121 0.0361 0.1515
Schistosoma mansoni retinoid-x-receptor (RXR) 0.0047 0.009 0.0117
Echinococcus granulosus endonuclease exonuclease phosphatase 0.0201 0.0648 0.0849
Brugia malayi Nuclear hormone receptor family member nhr-49 0.0047 0.009 0.0124
Echinococcus granulosus importin subunit beta 1 0.0022 0.0002 0.0002
Loa Loa (eye worm) hypothetical protein 0.006 0.0137 0.0444
Echinococcus multilocularis casein kinase I delta 0.0624 0.2187 0.2865
Loa Loa (eye worm) hypothetical protein 0.0047 0.009 0.029
Loa Loa (eye worm) hypothetical protein 0.0051 0.0107 0.0345
Trichomonas vaginalis phosphofructokinase, putative 0.0121 0.0361 0.0824
Schistosoma mansoni ubiquitously transcribed sex (X/Y) chromosome tetratricopeptide repeat protein-related 0.003 0.0029 0.0038
Trichomonas vaginalis conserved hypothetical protein 0.0026 0.0014 0.0014
Brugia malayi Cathepsin L-like precursor 0.0024 0.0008 0.0012
Echinococcus multilocularis cAMP dependent protein kinase catalytic subunit 0.0046 0.0086 0.0113
Echinococcus multilocularis casein kinase i 0.0624 0.2187 0.2865
Schistosoma mansoni heat shock protein 0.0082 0.0219 0.0287
Leishmania major tyrosyl-DNA phosphodiesterase 1 0.0069 0.0172 0.0637
Echinococcus granulosus ribosomal protein L19 0.0028 0.002 0.0026
Onchocerca volvulus Polycomb protein Sfmbt homolog 0.005 0.0102 0.0102
Brugia malayi Nuclear hormone receptor family member nhr-14 0.0047 0.009 0.0124
Loa Loa (eye worm) hypothetical protein 0.0042 0.0071 0.0229
Trypanosoma cruzi cAMP-dependent protein kinase catalytic subunit 3 0.0046 0.0086 0.0316
Echinococcus multilocularis sterol regulatory element binding protein 0.0027 0.0017 0.0023
Toxoplasma gondii casein kinase I 0.0624 0.2187 0.8182
Onchocerca volvulus 0.0024 0.0008 0.0008
Brugia malayi 6-phosphofructokinase 0.0121 0.0361 0.0498
Echinococcus multilocularis expressed protein 0.0417 0.1434 0.1879
Trichomonas vaginalis fructose-bisphosphate aldolase, putative 0.1203 0.4289 1
Leishmania major DNA polymerase kappa, putative 0.0063 0.0148 0.0547
Schistosoma mansoni hypothetical protein 0.0026 0.0014 0.0019
Trypanosoma cruzi mitochondrial DNA polymerase beta, putative 0.0321 0.1084 0.4052
Onchocerca volvulus 0.0076 0.0197 0.0197
Mycobacterium leprae DIHYDROLIPOAMIDE DEHYDROGENASE LPD (LIPOAMIDE REDUCTASE (NADH)) (LIPOYL DEHYDROGENASE) (DIHYDROLIPOYL DEHYDROGENASE) (DIAPHORASE 0.0102 0.029 0.094
Echinococcus multilocularis FTZ F1 alpha 0.0047 0.009 0.0117
Echinococcus granulosus lamin 0.0061 0.0141 0.0185
Echinococcus granulosus twitchin 0.0044 0.0079 0.0104
Trypanosoma brucei 60S ribosomal protein L19, putative 0.0028 0.002 0.0068
Onchocerca volvulus Cathepsin L homolog 0.0024 0.0008 0.0008
Loa Loa (eye worm) nuclear hormone receptor family member nhr-14 0.0047 0.009 0.029
Trichomonas vaginalis fructose-bisphosphate aldolase, putative 0.1203 0.4289 1
Brugia malayi RNA binding protein 0.0206 0.0669 0.0923
Leishmania major heat shock protein 83-1 0.0082 0.0219 0.0812
Loa Loa (eye worm) hypothetical protein 0.007 0.0174 0.0562
Echinococcus granulosus heat shock protein 75 kDa mitochondrial 0.0046 0.0087 0.0114
Entamoeba histolytica chromodomain-helicase-DNA-binding protein, putative 0.0026 0.0014 0.0014
Mycobacterium ulcerans fatty-acid-CoA ligase 0.0038 0.0059 0.0003
Trypanosoma cruzi cAMP-dependent protein kinase catalytic subunit 2 0.0046 0.0086 0.0316
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0093 0.0257 0.0956
Echinococcus multilocularis Chromobox protein 3 0.0026 0.0014 0.0019
Schistosoma mansoni chromobox protein 0.0159 0.0497 0.0652
Echinococcus multilocularis nuclear receptor 2DBD gamma 0.0047 0.009 0.0117
Brugia malayi TAR-binding protein 0.0206 0.0669 0.0923
Schistosoma mansoni coup transcription factor 0.0047 0.009 0.0117
Trichomonas vaginalis conserved hypothetical protein 0.0026 0.0014 0.0014
Loa Loa (eye worm) CMGC/CDK/CDC2 protein kinase 0.0059 0.0134 0.0433
Brugia malayi jmjC domain containing protein 0.003 0.0029 0.004
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0093 0.0257 0.0956
Entamoeba histolytica tyrosyl-DNA phosphodiesterase, putative 0.0069 0.0172 0.0382
Onchocerca volvulus 0.0024 0.0008 0.0008
Trichomonas vaginalis penicillin-binding protein, putative 0.0054 0.0118 0.0255
Echinococcus granulosus TGF beta signal transducer SmadC 0.0025 0.0009 0.0012
Brugia malayi Hypothetical 52.5 kDa protein ZK945.1 in chromosome II, putative 0.0054 0.0118 0.0162
Schistosoma mansoni Smad4 0.0025 0.0009 0.0012
Onchocerca volvulus 0.0026 0.0014 0.0014
Entamoeba histolytica deoxycytidyl transferase, putative 0.0056 0.0122 0.0266
Brugia malayi heat shock protein 90 0.0082 0.0219 0.0302
Echinococcus granulosus single minded 2 0.0038 0.0059 0.0077
Toxoplasma gondii 'chromo' (CHRromatin Organization MOdifier) domain-containing protein 0.0026 0.0014 0.0048
Onchocerca volvulus 0.0061 0.0141 0.0141
Loa Loa (eye worm) intermediate filament tail domain-containing protein 0.0061 0.0141 0.0457
Trypanosoma brucei unspecified product 0.0077 0.02 0.0742
Schistosoma mansoni nephrin 0.0035 0.0046 0.0061
Loa Loa (eye worm) hypothetical protein 0.0028 0.0023 0.0073
Echinococcus granulosus GPCR family 2 0.0069 0.0169 0.0221
Schistosoma mansoni hypothetical protein 0.0026 0.0014 0.0018
Plasmodium vivax topoisomerase I, putative 0.02 0.0647 0.2417
Schistosoma mansoni hypothetical protein 0.0026 0.0014 0.0018
Onchocerca volvulus 0.0143 0.0439 0.0439
Loa Loa (eye worm) mbt repeat family protein 0.005 0.0102 0.033
Echinococcus multilocularis cysteine protease 0.0024 0.0008 0.0011
Echinococcus granulosus mothers against decapentaplegic 5 0.0025 0.0009 0.0012
Brugia malayi Papain family cysteine protease containing protein 0.0024 0.0008 0.0012
Trichomonas vaginalis conserved hypothetical protein 0.0034 0.0043 0.008
Loa Loa (eye worm) hypothetical protein 0.0031 0.0034 0.0111
Onchocerca volvulus 0.0051 0.0107 0.0107
Onchocerca volvulus 0.0624 0.2187 0.2187
Echinococcus granulosus COUP TF:Svp nuclear hormone receptor 0.0047 0.009 0.0117
Echinococcus multilocularis nuclear receptor subfamily 1 group D 0.0025 0.001 0.0013
Plasmodium falciparum protein kinase 5 0.0059 0.0134 0.0495
Leishmania major casein kinase, putative 0.0624 0.2187 0.8182
Schistosoma mansoni serine/threonine protein kinase 0.0031 0.0031 0.004
Trichomonas vaginalis conserved hypothetical protein 0.0027 0.0017 0.0021
Schistosoma mansoni hypothetical protein 0.024 0.0792 0.1037
Trypanosoma cruzi cysteine peptidase, putative 0.0093 0.0257 0.0955
Loa Loa (eye worm) CMGC/CDK/CDK5 protein kinase 0.0059 0.0134 0.0433
Echinococcus granulosus dna polymerase eta 0.008 0.0212 0.0277
Entamoeba histolytica hypothetical protein 0.0083 0.0222 0.0498
Brugia malayi serine/threonine-protein kinase plk-2 0.0114 0.0335 0.0462
Mycobacterium tuberculosis Probable fructose-bisphosphate aldolase Fba 0.0588 0.2054 1
Loa Loa (eye worm) CK1/CK1/CK1-A protein kinase 0.0624 0.2187 0.7081
Echinococcus granulosus cadherin EGF LAG seven pass G type receptor 0.0069 0.0169 0.0221
Brugia malayi C2-HC type zinc finger protein C.e-MyT1 0.0057 0.0127 0.0175
Echinococcus granulosus casein kinase I alpha 0.0624 0.2187 0.2865
Trypanosoma brucei DNA topoisomerase type IB small subunit 0.005 0.0103 0.0378
Echinococcus multilocularis Niemann Pick C1 protein 0.0062 0.0147 0.0192
Toxoplasma gondii heat shock protein 75, putative 0.0046 0.0087 0.0319
Plasmodium falciparum acyl-CoA synthetase 0.0038 0.0059 0.0216
Loa Loa (eye worm) thioredoxin reductase 0.004 0.0066 0.0213
Loa Loa (eye worm) hypothetical protein 0.0062 0.0147 0.0475
Trichomonas vaginalis dexras1, putative 0.0061 0.0141 0.031
Trichomonas vaginalis chromobox protein, putative 0.0026 0.0014 0.0014
Trypanosoma cruzi casein kinase, putative 0.0624 0.2187 0.8182
Echinococcus multilocularis geminin 0.0278 0.093 0.1219
Echinococcus granulosus phd:f box containing protein 0.003 0.0029 0.0038
Brugia malayi AF-10 protein 0.003 0.0031 0.0042
Schistosoma mansoni hypothetical protein 0.0069 0.0169 0.0221
Trichomonas vaginalis heat shock protein, putative 0.0056 0.0123 0.0268
Echinococcus multilocularis cathepsin l cysteine peptidase 0.0024 0.0008 0.0011
Brugia malayi Nuclear hormone receptor family member nhr-25 0.0047 0.009 0.0124
Brugia malayi SET domain containing protein 0.0032 0.0036 0.005
Trichomonas vaginalis chromobox protein, putative 0.0159 0.0497 0.1143
Plasmodium vivax heat shock protein 90, putative 0.0046 0.0087 0.0319
Entamoeba histolytica hypothetical protein 0.0083 0.0222 0.0498
Loa Loa (eye worm) hypothetical protein 0.0047 0.009 0.029
Plasmodium falciparum cysteine proteinase falcipain 2a 0.0024 0.0008 0.0025
Echinococcus multilocularis phd:f box containing protein 0.003 0.0029 0.0038
Trichomonas vaginalis D-aminoacylase, putative 0.0054 0.0118 0.0255
Brugia malayi Telomerase reverse transcriptase 0.2017 0.7247 1
Mycobacterium ulcerans beta-lactamase 0.0054 0.0118 0.0295
Plasmodium falciparum heat shock protein 90 0.0082 0.0219 0.0813
Echinococcus granulosus retinoic acid receptor rxr beta a 0.0047 0.009 0.0117
Plasmodium falciparum cysteine proteinase falcipain 2b 0.0024 0.0008 0.0025
Brugia malayi Cathepsin L-like precursor 0.0024 0.0008 0.0012
Brugia malayi Cathepsin L-like precursor 0.0024 0.0008 0.0012
Echinococcus granulosus FTZ F1 alpha 0.0047 0.009 0.0117
Trichomonas vaginalis rheb, putative 0.0061 0.0141 0.031
Mycobacterium tuberculosis Putative ferredoxin reductase 0.0092 0.0253 0.1003
Brugia malayi MH1 domain containing protein 0.0025 0.0009 0.0013
Loa Loa (eye worm) hypothetical protein 0.0042 0.0071 0.0231
Trypanosoma cruzi heat shock protein 85, putative 0.0082 0.0219 0.0812
Loa Loa (eye worm) hypothetical protein 0.0028 0.002 0.0064
Schistosoma mansoni lipoxygenase 0.0054 0.0117 0.0154
Brugia malayi bHLH-PAS transcription factor 0.0038 0.0059 0.0081
Echinococcus multilocularis JmjC domain containing protein 4 0.003 0.0029 0.0038
Trypanosoma brucei unspecified product 0.0038 0.0059 0.0216
Leishmania major cysteine peptidase A (CPA) 0.0024 0.0008 0.0025
Mycobacterium tuberculosis Probable hydrolase 0.0054 0.0118 0.0328
Schistosoma mansoni mixed-lineage leukemia protein mll 0.0051 0.0105 0.0138
Trypanosoma brucei protein kinase A catalytic subunit, putative 0.0046 0.0086 0.0317
Schistosoma mansoni jumonji domain containing protein 0.003 0.0029 0.0038
Schistosoma mansoni Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) 0.0093 0.0258 0.0337
Loa Loa (eye worm) tyrosyl-DNA phosphodiesterase 0.0069 0.0172 0.0556
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0093 0.0257 0.0956
Trypanosoma cruzi cdc2-related kinase 1 0.0059 0.0134 0.0494
Schistosoma mansoni hypothetical protein 0.0093 0.0259 0.0339
Echinococcus multilocularis cAMP dependent protein kinase catalytic subunit 0.0046 0.0086 0.0113
Echinococcus granulosus hepatocyte nuclear factor 4 alpha 0.0047 0.009 0.0117
Schistosoma mansoni hypothetical protein 0.0076 0.0197 0.0258
Loa Loa (eye worm) CXXC zinc finger family protein 0.0064 0.0153 0.0495
Schistosoma mansoni lipoxygenase 0.0078 0.0202 0.0265
Schistosoma mansoni serine/threonine protein kinase 0.0059 0.0134 0.0175
Loa Loa (eye worm) hypothetical protein 0.0247 0.0817 0.2646
Echinococcus granulosus Nuclear hormone receptor family member nhr 41 0.0047 0.009 0.0117
Echinococcus granulosus cAMP dependent protein kinase catalytic subunit 0.0046 0.0086 0.0113
Brugia malayi metabotropic glutamate receptor subtype 5a (mGluR5a), putative 0.0031 0.0031 0.0043
Schistosoma mansoni smad 0.0025 0.0009 0.0012
Loa Loa (eye worm) ICD-1 protein 0.0034 0.0043 0.0138
Mycobacterium ulcerans DNA polymerase IV 0.0084 0.0225 0.0836
Plasmodium vivax vivapain-2 0.0024 0.0008 0.0025
Echinococcus multilocularis beta adrenergic receptor kinase 0.0031 0.0031 0.004
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0093 0.0257 0.0956
Trichomonas vaginalis Heterochromatin protein, putative 0.0026 0.0014 0.0014
Giardia lamblia Heat shock protein HSP 90-alpha 0.0068 0.0168 0.0348
Schistosoma mansoni histone-lysine n-methyltransferase setb1 0.0143 0.0439 0.0575
Echinococcus granulosus aldehyde dehydrogenase mitochondrial 0.0047 0.0092 0.012
Echinococcus multilocularis beta LACTamase domain containing family member 0.0054 0.0118 0.0154
Brugia malayi Metabotropic glutamate receptor precursor. 0.0034 0.0043 0.0059
Echinococcus multilocularis DNA topoisomerase 1 0.02 0.0647 0.0848
Loa Loa (eye worm) hypothetical protein 0.003 0.0029 0.0095
Loa Loa (eye worm) abnormal chemotaxis protein 14 0.0027 0.0017 0.0056
Schistosoma mansoni smad1 5 8 and 0.0025 0.0009 0.0012
Echinococcus granulosus suppression of tumorigenicity 18 protein 0.0057 0.0127 0.0167
Plasmodium vivax JmjC domain containing protein 0.003 0.0029 0.0103
Leishmania major hypothetical protein, conserved 0.003 0.0029 0.0103
Schistosoma mansoni serine/threonine protein kinase 0.0624 0.2187 0.2865
Leishmania major CYC2-like cyclin, putative 0.003 0.003 0.0106
Echinococcus granulosus Chromobox protein 3 0.0026 0.0014 0.0019
Echinococcus granulosus dnaJ subfamily B 0.0913 0.3237 0.4239
Schistosoma mansoni retinoid-x-receptor (RXR) 0.0025 0.001 0.0013
Entamoeba histolytica hypothetical protein 0.0083 0.0222 0.0498
Loa Loa (eye worm) hypothetical protein 0.0106 0.0305 0.0989
Plasmodium falciparum heat shock protein 90, putative 0.0196 0.0633 0.2365
Mycobacterium leprae PROBABLE CHAPERONE PROTEIN HTPG (HEAT SHOCK PROTEIN) (HSP90 FAMILY PROTEIN) (HIGH TEMPERATURE PROTEIN G) 0.0072 0.0183 0.0391
Loa Loa (eye worm) hypothetical protein 0.0022 0.0002 0.0005
Leishmania major heat shock protein 83-1 0.0082 0.0219 0.0812
Mycobacterium tuberculosis Probable aldehyde dehydrogenase 0.0047 0.0092 0.0201
Trypanosoma cruzi DNA topoisomerase type IB small subunit, putative 0.005 0.0103 0.0378
Trypanosoma cruzi DNA polymerase beta thumb, putative 0.0045 0.0084 0.0306
Loa Loa (eye worm) hypothetical protein 0.0025 0.001 0.0031
Echinococcus multilocularis atpase aaa+ type core atpase aaa type core 0.1635 0.586 0.7675
Onchocerca volvulus 0.0061 0.0141 0.0141
Trichomonas vaginalis CMGC family protein kinase 0.0059 0.0134 0.0293
Schistosoma mansoni chromobox protein-related (chromobox 1) (heterochromatin 1) 0.0026 0.0014 0.0019
Brugia malayi ImpB/MucB/SamB family protein 0.008 0.0212 0.0292
Echinococcus multilocularis neuropeptide s receptor 0.1131 0.4029 0.5277
Echinococcus multilocularis cpg binding protein 0.007 0.0173 0.0226
Onchocerca volvulus 0.0095 0.0265 0.0265
Onchocerca volvulus 0.0054 0.0118 0.0118
Echinococcus multilocularis tm gpcr rhodopsin gpcr rhodopsin superfamily 0.0642 0.2253 0.2951
Schistosoma mansoni hypothetical protein 0.0148 0.0458 0.0599
Loa Loa (eye worm) hypothetical protein 0.0247 0.0817 0.2646
Echinococcus multilocularis chromodomain helicase DNA binding protein 1 0.0026 0.0014 0.0019
Loa Loa (eye worm) hypothetical protein 0.0025 0.001 0.0031
Echinococcus granulosus Chromo domain 0.0026 0.0014 0.0019
Plasmodium falciparum glutathione reductase 0.004 0.0066 0.024
Mycobacterium ulcerans long-chain-fatty-acid--CoA ligase 0.0051 0.0107 0.024
Mycobacterium tuberculosis Probable 6-phosphofructokinase PfkA (phosphohexokinase) (phosphofructokinase) 0.0121 0.0361 0.1544
Trypanosoma cruzi cysteine peptidase, putative 0.0024 0.0008 0.0025
Onchocerca volvulus Protein ultraspiracle homolog 0.0047 0.009 0.009
Onchocerca volvulus 0.0428 0.1474 0.1474
Chlamydia trachomatis acylglycerophosphoethanolamine acyltransferase 0.0038 0.0059 1
Echinococcus granulosus beta LACTamase domain containing family member 0.0054 0.0118 0.0154
Echinococcus multilocularis Jumonji, AT rich interactive domain 1B 0.0036 0.0049 0.0064
Loa Loa (eye worm) nuclear hormone receptor family member nhr-49 0.0047 0.009 0.029
Echinococcus multilocularis PHD finger protein rhinoceros 0.0093 0.0259 0.0339
Schistosoma mansoni survival motor neuron protein 0.0076 0.0197 0.0258
Echinococcus multilocularis ribosomal protein L19 0.0028 0.002 0.0026
Loa Loa (eye worm) hypothetical protein 0.0026 0.0014 0.0047
Onchocerca volvulus Cathepsin F homolog 0.0024 0.0008 0.0008
Trichomonas vaginalis chromobox protein, putative 0.0159 0.0497 0.1143
Entamoeba histolytica casein kinase, putative 0.0624 0.2187 0.509
Loa Loa (eye worm) hypothetical protein 0.0148 0.0458 0.1481
Mycobacterium tuberculosis Probable reductase 0.0092 0.0253 0.1003
Trypanosoma cruzi mitochondrial DNA polymerase beta-PAK, putative 0.0045 0.0084 0.0306
Mycobacterium ulcerans lipase LipD 0.0054 0.0118 0.0295
Onchocerca volvulus Alhambra homolog 0.0093 0.0259 0.0259
Brugia malayi Protein kinase domain containing protein 0.0426 0.1466 0.2023
Entamoeba histolytica acyl-CoA synthetase, putative 0.0051 0.0107 0.0229
Echinococcus granulosus beta-adrenergic receptor kinase 0.0031 0.0031 0.004
Giardia lamblia Kinase, AGC PKA 0.0046 0.0086 0.0156
Schistosoma mansoni chromobox protein 0.0026 0.0014 0.0019
Trichomonas vaginalis chromodomain helicase DNA binding protein, putative 0.0041 0.0067 0.0137
Toxoplasma gondii histone lysine methyltransferase SET/SUV39 0.0126 0.0379 0.1412
Brugia malayi RNA recognition motif domain containing protein 0.0206 0.0669 0.0923
Leishmania major cathepsin L-like protease 0.0024 0.0008 0.0025
Schistosoma mansoni endoplasmin 0.0082 0.0219 0.0287
Loa Loa (eye worm) glutathione reductase 0.004 0.0066 0.0213
Echinococcus multilocularis polycomb protein SCMH1 0.005 0.0102 0.0134
Loa Loa (eye worm) hypothetical protein 0.0038 0.0059 0.0192
Brugia malayi Corticotropin releasing factor receptor 2 precursor, putative 0.0217 0.0706 0.0975
Plasmodium vivax SET domain protein, putative 0.0126 0.0379 0.1412
Schistosoma mansoni transcription factor btf3 0.0034 0.0043 0.0056
Trypanosoma brucei unspecified product 0.0038 0.0059 0.0216
Mycobacterium tuberculosis Probable esterase LipL 0.0054 0.0118 0.0328
Brugia malayi Thioredoxin reductase 0.004 0.0066 0.0091
Trypanosoma cruzi telomerase reverse transcriptase, putative 0.0758 0.2673 1
Toxoplasma gondii heat shock protein HSP90 0.0082 0.0219 0.0813
Echinococcus granulosus lysine specific demethylase 6a 0.003 0.0029 0.0038
Schistosoma mansoni sex comb on midleg homolog 0.005 0.0102 0.0134
Entamoeba histolytica hypothetical protein 0.0026 0.0014 0.0014
Echinococcus granulosus defective proboscis extension response 0.0031 0.0034 0.0045
Brugia malayi nuclear receptor RXR 0.0025 0.001 0.0013
Brugia malayi Bromodomain containing protein 0.0076 0.0196 0.0271
Loa Loa (eye worm) ctsf protein 0.0024 0.0008 0.0027
Brugia malayi Bromodomain containing protein 0.0037 0.0054 0.0075
Toxoplasma gondii PHD-finger domain-containing protein 0.0093 0.0259 0.0962
Echinococcus granulosus casein kinase I delta 0.0624 0.2187 0.2865
Trichomonas vaginalis chromodomain helicase DNA binding protein, putative 0.0041 0.0067 0.0137
Plasmodium vivax hypothetical protein, conserved 0.0026 0.0014 0.0048
Entamoeba histolytica phosphofructokinase, putative 0.0121 0.0361 0.0824
Schistosoma mansoni jumonji domain containing protein 0.0243 0.0801 0.1049
Echinococcus multilocularis rho associated protein kinase 0.0143 0.0439 0.0575
Schistosoma mansoni scm-relatedprotein containing 4 mbt domains (sfmbt) 0.005 0.0102 0.0134
Echinococcus multilocularis Immunoglobulin 0.0031 0.0034 0.0045
Leishmania major heat shock protein 83-1 0.0082 0.0219 0.0812
Brugia malayi Cathepsin L-like precursor 0.0024 0.0008 0.0012
Toxoplasma gondii histone lysine demethylase JMJC1/KDM5D/JARID1D 0.003 0.0029 0.0103
Trichomonas vaginalis DNA polymerase eta, putative 0.0084 0.0225 0.0507
Leishmania major heat shock protein 83-1 0.0082 0.0219 0.0812
Toxoplasma gondii cyclin, N-terminal domain-containing protein 0.003 0.003 0.0107
Schistosoma mansoni kinase 0.0062 0.0147 0.0192
Echinococcus granulosus Jumonji AT rich interactive domain 1B 0.0036 0.0049 0.0064
Trypanosoma cruzi cysteine peptidase, clan CA, family C1, cathepsin L-like, putative 0.0085 0.0228 0.0846
Schistosoma mansoni TGF-beta signal transducer Smad2 0.0025 0.0009 0.0012
Echinococcus granulosus guanine nucleotide binding protein Gs subunit 0.0093 0.0258 0.0337
Brugia malayi ImpB/MucB/SamB family protein 0.0056 0.0122 0.0169
Echinococcus granulosus enhancer of mRNA decapping protein 4 0.0037 0.0053 0.007
Schistosoma mansoni RAR-like nuclear receptor 0.0047 0.009 0.0117
Echinococcus multilocularis ras gtpase 0.0061 0.0141 0.0185
Loa Loa (eye worm) hypothetical protein 0.0047 0.009 0.029
Brugia malayi Nuclear hormone receptor family member nhr-19 0.0047 0.009 0.0124
Leishmania major DNA topoisomerase IB, large subunit 0.015 0.0464 0.1732
Echinococcus granulosus histone lysine methyltransferase setb 0.0143 0.0439 0.0575
Loa Loa (eye worm) heterochromatin protein 1 0.0159 0.0497 0.161
Trypanosoma brucei DNA polymerase kappa, putative 0.0084 0.0225 0.0838
Brugia malayi beta-lactamase family protein 0.0054 0.0118 0.0162
Loa Loa (eye worm) Smad1 0.0025 0.0009 0.003
Leishmania major heat shock protein 83-1 0.0082 0.0219 0.0812
Trichomonas vaginalis CK1 family protein kinase 0.0624 0.2187 0.509
Echinococcus multilocularis endonuclease exonuclease phosphatase 0.0201 0.0648 0.0849
Schistosoma mansoni cathepsin F (C01 family) 0.0024 0.0008 0.0011
Echinococcus multilocularis mothers against decapentaplegic 5 0.0025 0.0009 0.0012
Brugia malayi beta-lactamase 0.0054 0.0118 0.0162
Loa Loa (eye worm) hypothetical protein 0.0054 0.0118 0.038
Onchocerca volvulus Huntingtin homolog 0.0247 0.0817 0.0817
Toxoplasma gondii PHD-finger domain-containing protein 0.0093 0.0259 0.0962
Loa Loa (eye worm) AGC/PKA protein kinase 0.0046 0.0086 0.0279
Echinococcus multilocularis 6 phosphofructokinase 0.0121 0.0361 0.0473
Entamoeba histolytica fructose-1,6-bisphosphate aldolase, putative 0.1203 0.4289 1
Schistosoma mansoni tar DNA-binding protein 0.0206 0.0669 0.0876
Trypanosoma cruzi cAMP-dependent protein kinase catalytic subunit 1 0.0046 0.0086 0.0316
Onchocerca volvulus Heterochromatin protein 1 homolog 0.0089 0.0244 0.0244
Echinococcus granulosus DNA topoisomerase 1 0.02 0.0647 0.0848
Schistosoma mansoni thyroid hormone receptor 0.0047 0.009 0.0117
Treponema pallidum fructose-bisphosphate aldolase 0.1203 0.4289 1
Mycobacterium tuberculosis Probable dehydrogenase 0.0092 0.0253 0.1003
Trypanosoma cruzi hypothetical protein, conserved 0.0054 0.0118 0.0433
Loa Loa (eye worm) runx1 0.0054 0.0115 0.0372
Toxoplasma gondii heat shock protein 90, putative 0.0082 0.0219 0.0813
Brugia malayi cAMP-dependent protein kinase catalytic subunit, putative 0.0046 0.0086 0.0119
Trypanosoma cruzi CYC2-like cyclin, putative 0.003 0.003 0.0106
Loa Loa (eye worm) AGC/GRK/BARK protein kinase 0.0031 0.0031 0.01
Brugia malayi beta-lactamase family protein 0.0054 0.0118 0.0162
Loa Loa (eye worm) jmjC domain-containing protein 0.0118 0.035 0.1132
Echinococcus multilocularis lysine specific demethylase 5A 0.0113 0.033 0.0432
Leishmania major heat shock protein 83-1 0.0082 0.0219 0.0812
Brugia malayi mbt repeat family protein 0.005 0.0102 0.0141
Plasmodium falciparum thioredoxin reductase 0.004 0.0066 0.024
Toxoplasma gondii phosphofructokinase domain-containing protein 0.0033 0.0039 0.014
Echinococcus multilocularis fetal alzheimer antigen, falz 0.0025 0.0012 0.0016
Plasmodium vivax casein kinase 1, putative 0.0624 0.2187 0.8182
Trypanosoma cruzi tyrosyl-DNA Phosphodiesterase (Tdp1), putative 0.0069 0.0172 0.0637
Leishmania major heat shock protein 83-1 0.0082 0.0219 0.0812
Trypanosoma brucei heat shock protein 90, putative 0.0082 0.0219 0.0813
Entamoeba histolytica serine/threonine protein kinase, putative 0.0114 0.0335 0.0763
Brugia malayi photoreceptor-specific nuclear receptor 0.0047 0.009 0.0124
Trypanosoma brucei DNA polymerase kappa, putative 0.0045 0.0085 0.0312
Trichomonas vaginalis conserved hypothetical protein 0.0034 0.0043 0.008
Schistosoma mansoni hypothetical protein 0.0026 0.0014 0.0018
Echinococcus granulosus macrophage colony stimulating factor 1 receptor 0.0288 0.0966 0.1265
Trichomonas vaginalis chromodomain helicase DNA binding protein, putative 0.0026 0.0014 0.0014
Mycobacterium tuberculosis Probable chaperone protein HtpG (heat shock protein) (HSP90 family protein) (high temperature protein G) 0.0072 0.0183 0.0654
Brugia malayi 6-phosphofructokinase 0.0121 0.0361 0.0498
Echinococcus multilocularis Transcription factor, JmjC domain containing protein 0.0305 0.1029 0.1348
Loa Loa (eye worm) cytoplasmic intermediate filament protein 0.0033 0.0038 0.0124
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0093 0.0257 0.0956
Loa Loa (eye worm) hypothetical protein 0.0047 0.009 0.029
Schistosoma mansoni smad1 5 8 and 0.0025 0.0009 0.0012
Onchocerca volvulus 0.0152 0.0473 0.0473
Echinococcus multilocularis neuropeptide receptor A26 0.1131 0.4029 0.5277
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0093 0.0257 0.0956
Echinococcus granulosus neuroglian 0.0035 0.0046 0.0061
Trypanosoma cruzi DNA polymerase beta thumb, putative 0.0045 0.0084 0.0306
Loa Loa (eye worm) hypothetical protein 0.0027 0.0017 0.0056
Echinococcus multilocularis peregrin 0.0096 0.0267 0.0349
Loa Loa (eye worm) jmjC domain-containing protein 0.003 0.0029 0.0095
Trichomonas vaginalis 60S ribosomal protein L19, putative 0.0028 0.002 0.0027
Loa Loa (eye worm) hypothetical protein 0.0047 0.009 0.029
Trichomonas vaginalis CMGC family protein kinase 0.0059 0.0134 0.0293
Entamoeba histolytica hypothetical protein 0.0034 0.0043 0.008
Trypanosoma cruzi DNA polymerase kappa, putative 0.0084 0.0225 0.0837
Brugia malayi hypothetical protein 0.0025 0.001 0.0013
Trichomonas vaginalis CAMK family protein kinase 0.0114 0.0335 0.0763
Onchocerca volvulus 0.005 0.0102 0.0102
Mycobacterium ulcerans acyl-CoA synthetase 0.0051 0.0107 0.024
Echinococcus granulosus Smad4 0.0025 0.0009 0.0012
Onchocerca volvulus 0.0064 0.0153 0.0153
Trypanosoma brucei DNA polymerase kappa, putative 0.0084 0.0225 0.0838
Entamoeba histolytica 60S ribosomal protein L19, putative 0.0028 0.002 0.0027
Echinococcus multilocularis roundabout 2 0.0042 0.0071 0.0093
Brugia malayi glutathione reductase 0.004 0.0066 0.0091
Trichomonas vaginalis chromodomain-helicase-DNA-binding protein, putative 0.0026 0.0014 0.0014
Schistosoma mansoni DNA topoisomerase type I 0.02 0.0647 0.0848
Toxoplasma gondii hypothetical protein 0.0052 0.0108 0.0397
Brugia malayi CXXC zinc finger family protein 0.0064 0.0153 0.0211
Echinococcus granulosus arachidonate 5 lipoxygenase 0.0078 0.0202 0.0265
Brugia malayi AMP-binding enzyme family protein 0.0051 0.0107 0.0147
Loa Loa (eye worm) histone methyltransferase 0.0024 0.0009 0.0028
Trypanosoma brucei mitochondrial DNA polymerase beta-PAK 0.0152 0.0471 0.1757
Toxoplasma gondii cell-cycle-associated protein kinase CDK, putative 0.0059 0.0134 0.0495
Trypanosoma cruzi polo-like protein kinase, putative 0.0114 0.0335 0.1248
Schistosoma mansoni intermediate filament proteins 0.0061 0.0141 0.0185
Trypanosoma cruzi cruzipain precursor, putative 0.0093 0.0257 0.0955
Echinococcus granulosus microtubule associated protein 2 0.2124 0.7635 1
Toxoplasma gondii histone lysine demethylase JMJD6a 0.003 0.0029 0.0103
Onchocerca volvulus 0.0055 0.0121 0.0121
Entamoeba histolytica 90 kDa heat shock protein, putative 0.0046 0.0087 0.0183
Trichomonas vaginalis conserved hypothetical protein 0.0026 0.0014 0.0014
Echinococcus granulosus metabotropic glutamate receptor 2 0.0028 0.0023 0.003
Schistosoma mansoni bromodomain containing protein 0.0065 0.0155 0.0203
Trypanosoma brucei DNA polymerase kappa, putative 0.0084 0.0225 0.0838
Onchocerca volvulus Heat shock protein 75 kDa, mitochondrial homolog 0.0046 0.0087 0.0087
Toxoplasma gondii NAC domain-containing protein 0.0034 0.0043 0.0153
Leishmania major 4-coumarate:coa ligase-like protein 0.0051 0.0107 0.0392
Loa Loa (eye worm) hypothetical protein 0.0217 0.0706 0.2287
Schistosoma mansoni defective proboscis extension response (dpr)-related 0.0031 0.0034 0.0045
Entamoeba histolytica PH domain containing protein kinase, putative 0.0046 0.0086 0.0182
Echinococcus granulosus neuropeptide receptor A26 0.1131 0.4029 0.5277
Mycobacterium ulcerans fatty-acid-CoA ligase 0.0051 0.0107 0.024
Schistosoma mansoni myelin transcription factor 1 myt1 0.0057 0.0127 0.0167
Toxoplasma gondii aldehyde dehydrogenase 0.0047 0.0092 0.0338
Schistosoma mansoni lozenge 0.0054 0.0115 0.015
Leishmania major mitochondrial DNA polymerase beta 0.0321 0.1084 0.4052
Brugia malayi polk-prov protein 0.0046 0.0086 0.0119
Trypanosoma brucei casein kinase I, isoform 2 0.0624 0.2187 0.8182
Echinococcus granulosus rho-associated protein kinase 1 0.0143 0.0439 0.0575
Echinococcus multilocularis lysine specific demethylase 6a 0.003 0.0029 0.0038
Brugia malayi Intermediate filament tail domain containing protein 0.0061 0.0141 0.0195
Loa Loa (eye worm) cysteine protease 0.0024 0.0008 0.0027
Echinococcus granulosus 6 phosphofructokinase 0.0121 0.0361 0.0473
Brugia malayi Protein kinase domain containing protein 0.0059 0.0134 0.0185
Echinococcus granulosus chromodomain helicase DNA binding protein 4 0.0032 0.0034 0.0045
Schistosoma mansoni serine/threonine protein kinase 0.0046 0.0086 0.0113
Echinococcus multilocularis snurportin 1 0.024 0.0792 0.1037
Loa Loa (eye worm) hypothetical protein 0.0069 0.0169 0.0546
Schistosoma mansoni lamin 0.0061 0.0141 0.0185
Giardia lamblia Grp94/Hsp90 0.0072 0.0183 0.0382
Schistosoma mansoni metabotropic glutamate receptor 0.0028 0.0023 0.003
Loa Loa (eye worm) hypothetical protein 0.0055 0.0121 0.039
Echinococcus multilocularis enhancer of mRNA decapping protein 4 0.0037 0.0053 0.007
Entamoeba histolytica acyl-CoA synthetase, putative 0.0051 0.0107 0.0229
Echinococcus granulosus Immunoglobulin 0.0031 0.0034 0.0045
Echinococcus multilocularis protein dispatched 1 0.0031 0.0031 0.0041
Entamoeba histolytica 60S ribosomal protein L19, putative 0.0028 0.002 0.0027
Leishmania major heat shock protein 83-1 0.0082 0.0219 0.0812
Echinococcus multilocularis cyclin dependent kinase 5 0.0059 0.0134 0.0175
Onchocerca volvulus 0.0024 0.0008 0.0008
Echinococcus granulosus peregrin 0.0096 0.0267 0.0349
Leishmania major 4-coumarate:coa ligase-like protein 0.0051 0.0107 0.0392
Trichomonas vaginalis phosphofructokinase, putative 0.0121 0.0361 0.0824
Echinococcus granulosus chromobox protein 2 0.0026 0.0014 0.0019
Loa Loa (eye worm) hypothetical protein 0.0038 0.0059 0.0192
Schistosoma mansoni DNA polymerase eta 0.008 0.0212 0.0277
Trypanosoma brucei DNA polymerase kappa, putative 0.0084 0.0225 0.0838
Loa Loa (eye worm) hypothetical protein 0.0038 0.0059 0.0192
Trypanosoma cruzi DNA polymerase kappa, putative 0.0084 0.0225 0.0837
Giardia lamblia Kinase, CMGC CDK 0.0059 0.0134 0.0267
Loa Loa (eye worm) hypothetical protein 0.0054 0.0118 0.038
Brugia malayi Type III restriction enzyme, res subunit family protein 0.0026 0.0014 0.002
Trypanosoma brucei DNA polymerase IV, putative 0.0077 0.02 0.0742
Plasmodium falciparum chromodomain-helicase-DNA-binding protein 1 homolog, putative 0.0026 0.0014 0.0048
Trypanosoma brucei DNA polymerase IV, putative 0.0084 0.0225 0.0838
Mycobacterium leprae conserved hypothetical protein 0.0054 0.0118 0.0056
Onchocerca volvulus Bile acid receptor homolog 0.0047 0.009 0.009
Schistosoma mansoni ecdysone-induced protein 78c (dr-78) 0.0025 0.001 0.0013
Toxoplasma gondii RNA-directed DNA polymerase 0.0758 0.2673 1
Loa Loa (eye worm) ImpB/MucB/SamB family protein 0.0056 0.0122 0.0395
Trypanosoma brucei 60S ribosomal protein L19, putative 0.0028 0.002 0.0068
Schistosoma mansoni nuclear hormone receptor 0.0047 0.009 0.0117
Loa Loa (eye worm) hypothetical protein 0.0051 0.0107 0.0345
Entamoeba histolytica chromodomain-helicase-DNA-binding protein, putative 0.0026 0.0014 0.0014
Echinococcus granulosus FTZ F1 nuclear receptor protein 0.0047 0.009 0.0117
Trichomonas vaginalis CAMK family protein kinase 0.0114 0.0335 0.0763
Echinococcus multilocularis metabotropic glutamate receptor 2 0.0028 0.0023 0.003
Trichomonas vaginalis heat shock protein, putative 0.0082 0.0219 0.0492
Brugia malayi Nuclear hormone receptor family member nhr-19 0.0047 0.009 0.0124
Onchocerca volvulus 0.0047 0.009 0.009
Brugia malayi Pre-SET motif family protein 0.0126 0.0379 0.0523
Trypanosoma cruzi 60S ribosomal protein L19, putative 0.0028 0.002 0.0068
Echinococcus granulosus 5'partial|cyclin dependent kinase 1 0.0059 0.0134 0.0175
Leishmania major protein kinase A catalytic subunit isoform 2 0.0046 0.0086 0.0316
Trichomonas vaginalis phosphofructokinase, putative 0.0033 0.0039 0.0072
Trichomonas vaginalis chromobox protein, putative 0.0026 0.0014 0.0014
Schistosoma mansoni hypothetical protein 0.0278 0.093 0.1219
Echinococcus multilocularis SAM and MBT domain containing protein 0.005 0.0102 0.0134
Trichomonas vaginalis chromodomain helicase DNA binding protein, putative 0.0041 0.0067 0.0137
Loa Loa (eye worm) hypothetical protein 0.0054 0.0118 0.038
Echinococcus multilocularis diuretic hormone 44 receptor GPRdih2 0.0069 0.0169 0.0221
Loa Loa (eye worm) PLK/PLK1 protein kinase 0.0114 0.0335 0.1085
Trypanosoma brucei heat shock protein, putative 0.0082 0.0219 0.0813
Trypanosoma cruzi cysteine peptidase, putative 0.0093 0.0257 0.0955
Loa Loa (eye worm) hypothetical protein 0.0031 0.0034 0.0111
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0093 0.0257 0.0956
Echinococcus multilocularis ecdysone induced protein 78C 0.0047 0.009 0.0117
Trypanosoma cruzi CYC2-like cyclin 6, putative 0.003 0.003 0.0106
Brugia malayi casein kinase 1, delta 0.0624 0.2187 0.3018
Mycobacterium tuberculosis Probable NADH dehydrogenase Ndh 0.0092 0.0253 0.1003
Brugia malayi calcium-independent alpha-latrotoxin receptor 2, putative 0.0069 0.0169 0.0233
Loa Loa (eye worm) phosphofructokinase 0.0121 0.0361 0.1168
Brugia malayi Ligand-binding domain of nuclear hormone receptor family protein 0.0047 0.009 0.0124
Echinococcus multilocularis chromobox protein 1 0.0159 0.0497 0.0652
Entamoeba histolytica chromodomain-helicase-DNA-binding protein, putative 0.0026 0.0014 0.0014
Toxoplasma gondii 'chromo' (CHRromatin Organization MOdifier) domain-containing protein 0.0026 0.0014 0.0048
Mycobacterium leprae PROBABLE NADH DEHYDROGENASE NDH 0.0092 0.0253 0.0749
Loa Loa (eye worm) hypothetical protein 0.0025 0.001 0.0031
Echinococcus granulosus nuclear receptor 2DBD gamma 0.0047 0.009 0.0117
Brugia malayi latrophilin 2 splice variant baaae 0.0148 0.0458 0.0631
Trichomonas vaginalis ras-dva small GTPase, putative 0.0061 0.0141 0.031
Toxoplasma gondii thioredoxin reductase 0.004 0.0066 0.024
Echinococcus multilocularis tar DNA binding protein 0.0206 0.0669 0.0876
Loa Loa (eye worm) hypothetical protein 0.0061 0.0141 0.0457
Leishmania major heat shock protein 83-1 0.0082 0.0219 0.0812
Brugia malayi Nuclear hormone receptor family member nhr-1 0.0047 0.009 0.0124
Brugia malayi Endoplasmin precursor 0.0082 0.0219 0.0302
Loa Loa (eye worm) CMGC/CDK/CDC2 protein kinase 0.0059 0.0134 0.0433
Mycobacterium ulcerans hypothetical protein 0.0051 0.0107 0.024
Loa Loa (eye worm) CK1/CK1/CK1-A protein kinase 0.0624 0.2187 0.7081
Echinococcus multilocularis Basic leucine zipper (bZIP) transcription 0.0083 0.0222 0.029
Trypanosoma cruzi cdc2-related kinase 3 0.0059 0.0134 0.0494
Loa Loa (eye worm) MBCTL1 0.0057 0.0127 0.0412
Schistosoma mansoni phd/f-box containing protein 0.003 0.0029 0.0038
Schistosoma mansoni FTZ-F1 nuclear receptor-like protein 0.0047 0.009 0.0117
Schistosoma mansoni family S12 unassigned peptidase (S12 family) 0.0054 0.0118 0.0154
Loa Loa (eye worm) hypothetical protein 0.0045 0.0083 0.0268
Trichomonas vaginalis fructose-bisphosphate aldolase, putative 0.1203 0.4289 1
Loa Loa (eye worm) hypothetical protein 0.0037 0.0055 0.0177
Trichomonas vaginalis chromobox protein, putative 0.0096 0.0268 0.0607
Brugia malayi hypothetical protein 0.0026 0.0014 0.002
Schistosoma mansoni 6-phosphofructokinase 0.0121 0.0361 0.0473
Brugia malayi chromobox protein homolog 3 0.0089 0.0244 0.0336
Onchocerca volvulus 0.0993 0.3526 0.3526
Echinococcus multilocularis transcription factor btf3 0.0034 0.0043 0.0056
Schistosoma mansoni cathepsin F (C01 family) 0.0024 0.0008 0.0011
Wolbachia endosymbiont of Brugia malayi heat shock protein 90 0.0072 0.0183 0.5
Trichomonas vaginalis 60S ribosomal protein L19, putative 0.0028 0.002 0.0027
Echinococcus multilocularis cytoplasmic intermediate filament protein 0.0029 0.0027 0.0035
Onchocerca volvulus 0.0054 0.0118 0.0118
Schistosoma mansoni serine/threonine protein kinase 0.0046 0.0086 0.0113
Schistosoma mansoni vesicular amine transporter 0.0031 0.0034 0.0045
Loa Loa (eye worm) hypothetical protein 0.0374 0.128 0.4143
Trypanosoma cruzi casein kinase, putative 0.0624 0.2187 0.8182
Echinococcus multilocularis dnaJ subfamily B 0.0913 0.3237 0.4239
Loa Loa (eye worm) hypothetical protein 0.0026 0.0014 0.0047
Schistosoma mansoni chromobox protein-related (chromobox 1) (heterochromatin 1) 0.0026 0.0014 0.0019
Echinococcus multilocularis cyclin dependent kinase 0.0059 0.0134 0.0175
Trichomonas vaginalis 60S ribosomal protein L19, putative 0.0028 0.002 0.0027
Echinococcus multilocularis aldehyde dehydrogenase, mitochondrial 0.0047 0.0092 0.012
Schistosoma mansoni transcription factor LCR-F1 0.0083 0.0222 0.029
Trichomonas vaginalis conserved hypothetical protein 0.0026 0.0014 0.0014
Trypanosoma brucei cdc2-related kinase 1 0.0059 0.0134 0.0495
Plasmodium vivax hypothetical protein, conserved 0.0054 0.0118 0.0434
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0093 0.0257 0.0956
Brugia malayi PHD-finger family protein 0.0093 0.0259 0.0357
Echinococcus granulosus cpg binding protein 0.007 0.0173 0.0226
Echinococcus granulosus neurotracting:lsamp:neurotrimin:obcam 0.0038 0.0059 0.0077
Loa Loa (eye worm) hypothetical protein 0.005 0.0101 0.0326
Schistosoma mansoni hypothetical protein 0.0278 0.093 0.1219
Loa Loa (eye worm) nuclear hormone receptor family member nhr-41 0.0047 0.009 0.029
Schistosoma mansoni hypothetical protein 0.0083 0.0222 0.029
Onchocerca volvulus Heterochromatin protein 1 homolog 0.0096 0.0268 0.0268
Entamoeba histolytica Niemann-Pick C1 protein, putative 0.0062 0.0147 0.0323
Echinococcus granulosus cathepsin l cysteine peptidase 0.0024 0.0008 0.0011
Plasmodium falciparum JmjC domain-containing protein, putative 0.003 0.0029 0.0103
Loa Loa (eye worm) hypothetical protein 0.0054 0.0118 0.038
Trypanosoma brucei tyrosyl-DNA Phosphodiesterase (Tdp1), putative 0.0069 0.0172 0.0637
Trypanosoma cruzi 60S ribosomal protein L19, putative 0.0028 0.002 0.0068
Loa Loa (eye worm) helicase 0.0026 0.0014 0.0047
Loa Loa (eye worm) hypothetical protein 0.0024 0.0008 0.0027
Echinococcus multilocularis protein patched 0.0027 0.0017 0.0023
Leishmania major DNA polymerase kappa, putative,DNA polymerase IV, putative 0.0063 0.0148 0.0547
Giardia lamblia PHD finger protein 15 0.0093 0.0259 0.0559
Brugia malayi Nuclear hormone receptor-like 1 0.0025 0.001 0.0013
Echinococcus multilocularis terminal deoxycytidyl transferase rev1 0.0056 0.0122 0.016
Leishmania major heat shock protein 83-1 0.0082 0.0219 0.0812
Echinococcus multilocularis suppression of tumorigenicity 18 protein 0.0057 0.0127 0.0167
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0093 0.0257 0.0956
Trichomonas vaginalis conserved hypothetical protein 0.0026 0.0014 0.0014
Echinococcus multilocularis dna polymerase kappa 0.0084 0.0225 0.0295
Trypanosoma brucei heat shock protein, putative 0.0082 0.0219 0.0813
Echinococcus granulosus histone acetyltransferase MYST2 0.0057 0.0127 0.0167
Plasmodium vivax 6-phosphofructokinase, putative 0.0033 0.0039 0.014
Onchocerca volvulus 0.0024 0.0008 0.0008
Echinococcus multilocularis nuclear receptor 2DBD gamma 0.0047 0.009 0.0117
Echinococcus granulosus serine:threonine protein kinase PLK1 0.0114 0.0335 0.0439
Loa Loa (eye worm) hypothetical protein 0.0089 0.0244 0.0789
Loa Loa (eye worm) hypothetical protein 0.0057 0.0127 0.0412
Mycobacterium tuberculosis Probable oxidoreductase 0.0102 0.029 0.1188
Brugia malayi cell division control protein 2 homolog 0.0059 0.0134 0.0185
Echinococcus granulosus ribosomal protein L19 0.0028 0.002 0.0026
Loa Loa (eye worm) hypothetical protein 0.003 0.0029 0.0095
Brugia malayi Nuclear hormone receptor family member nhr-41 0.0047 0.009 0.0124
Echinococcus multilocularis Chromo domain 0.0026 0.0014 0.0019
Schistosoma mansoni sex comb on midleg homolog 0.005 0.0102 0.0134
Echinococcus granulosus SAM and MBT domain containing protein 0.005 0.0102 0.0134
Schistosoma mansoni photoreceptor-specific nuclear receptor related 0.0047 0.009 0.0117
Trichomonas vaginalis conserved hypothetical protein 0.003 0.003 0.0051
Echinococcus multilocularis guanine nucleotide binding protein G(s) subunit 0.0093 0.0258 0.0337
Toxoplasma gondii chromodomain helicase DNA binding protein CHD1/SWI2/SNF2 0.0026 0.0014 0.0048
Schistosoma mansoni single-minded 0.0052 0.0107 0.0141
Mycobacterium tuberculosis Probable esterase/lipase LipP 0.0054 0.0118 0.0328
Echinococcus granulosus nuclear receptor subfamily 1 group D 0.0025 0.001 0.0013
Echinococcus multilocularis TGF beta signal transducer SmadC 0.0025 0.0009 0.0012
Onchocerca volvulus Cathepsin L homolog 0.0024 0.0008 0.0008
Loa Loa (eye worm) papain family cysteine protease containing protein 0.0024 0.0008 0.0027
Trypanosoma cruzi cAMP-dependent protein kinase catalytic subunit 3 0.0046 0.0086 0.0316
Loa Loa (eye worm) hypothetical protein 0.0143 0.0439 0.142
Loa Loa (eye worm) hypoxia-induced factor 1 0.016 0.05 0.162
Brugia malayi cytoplasmic intermediate filament protein 0.0033 0.0038 0.0053

Activities

Activity type Activity value Assay description Source Reference
Ki (binding) = 1.6 nM Displacement of [125I]nociceptin from human NOP expressed in CHO cells ChEMBL. 19147350
Ki (binding) = 37 nM Displacement of [125I]diprenorphine from human MOP expressed in CHO cells ChEMBL. 19147350
Ki (binding) = 39 nM Displacement of [125I]diprenorphine from human KOP expressed in CHO cells ChEMBL. 19147350
Ki (binding) = 2064 nM Displacement of [125I]diprenorphine from human DOP expressed in CHO cells ChEMBL. 19147350

Phenotypes

Whole-cell/tissue/organism interactions

We have no records of whole-cell/tissue assays done with this compound What does this mean?

Many chemical entities in TDR Targets come from high-throughput screenings with whole cells or tissue samples, and not all assayed compounds have been tested against a single a single target protein, probably because they get ruled out during screening process. Even if these compounds may have not been of interest in the original screening, they may come as interesting leads for other screening assays. Furthermore, we may be able to propose drug-target associations using chemical similarities and network patterns.

Annotated phenotypes:

We have no manually annotated phenotypes for this drug. What does this mean? / Care to help?
In TDR Targets, information about phenotypes that are caused by drugs, or by genetic manipulation of cells (e.g. gene knockouts or knockdowns) is manually curated from the literature. These descriptions help to describe the potential of the target for drug development. If no information is available for this gene or if the information is incomplete, this may mean that i) the papers containing this information either appeared after the curation effort for this organism was carried out or they were inadvertently missed by curators; or that ii) the curation effort for this organism has not yet started.
 
In any case, if you have information about papers containing relevant validation data for this target, please log in using your TDR Targets username and password and send them to us using the corresponding form in this page (only visible to registered users) or contact us.

External resources for this compound

Bibliographic References

1 literature reference was collected for this gene.

If you have references for this compound, please enter them in a user comment (below) or Contact us.