Detailed information for compound 1005292

Basic information

Technical information
  • Name: Unnamed compound
  • MW: 579.52 | Formula: C30H32Cl2N6O2
  • H donors: 2 H acceptors: 4 LogP: 4.91 Rotable bonds: 13
    Rule of 5 violations (Lipinski): 2
  • SMILES: CCN(c1cc(nn1c1ccc(c(c1)Cl)Cl)c1cccnc1)CCCC(=O)NC(c1ccc(cc1)C)CC(=O)N
  • InChi: 1S/C30H32Cl2N6O2/c1-3-37(15-5-7-29(40)35-26(17-28(33)39)21-10-8-20(2)9-11-21)30-18-27(22-6-4-14-34-19-22)36-38(30)23-12-13-24(31)25(32)16-23/h4,6,8-14,16,18-19,26H,3,5,7,15,17H2,1-2H3,(H2,33,39)(H,35,40)
  • InChiKey: MFWOXFHPWBTGOW-UHFFFAOYSA-N  


Substructure search Similarity search

Network

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Synonyms

No synonyms found for this compound

Targets

Known targets for this compound

No curated genes were found associated with this compound

Predicted pathogen targets for this compound

By orthology
No druggable targets predicted by orthology data
By sequence similarity to non orthologous known druggable targets
No druggable targets predicted by sequence similarity
Obtained from network model

Ranking Plot

Putative Targets List

Species Potential target Raw Global Species
Brugia malayi polk-prov protein 0.0059 0.0327 0.11
Echinococcus multilocularis bromodomain adjacent to zinc finger domain 0.0039 0.0187 0.0187
Echinococcus granulosus chromobox protein 1 0.0148 0.0939 0.0938
Loa Loa (eye worm) hypothetical protein 0.0051 0.0276 0.0928
Mycobacterium tuberculosis Probable chain -fatty-acid-CoA ligase FadD13 (fatty-acyl-CoA synthetase) 0.0025 0.0092 0.0213
Mycobacterium tuberculosis Probable phosphoglycerate kinase Pgk 0.0183 0.1182 0.2862
Schistosoma mansoni protein phosphatase 2C 0.0027 0.0107 0.0107
Brugia malayi ThiF family protein 0.0033 0.015 0.0503
Giardia lamblia Ubiquitin-activating enzyme E1 1 0.0016 0.003 0.0125
Mycobacterium tuberculosis Inositol-1-monophosphatase SuhB 0.0036 0.0166 0.0394
Trypanosoma brucei unspecified product 0.0067 0.0384 0.0877
Brugia malayi ATP-dependent DNA helicase, RecQ family protein 0.0032 0.0142 0.0476
Echinococcus granulosus hepatocyte nuclear factor 4 alpha 0.0022 0.0071 0.0071
Entamoeba histolytica acyl-coA synthetase, putative 0.0025 0.0092 0.0434
Echinococcus multilocularis Jumonji, AT rich interactive domain 1B 0.0031 0.0133 0.0133
Trichomonas vaginalis disulfide oxidoreductase, putative 0.0012 0.0004 0.00000040069
Trypanosoma cruzi DNA polymerase beta thumb, putative 0.009 0.0542 0.1241
Leishmania major cathepsin L-like protease 0.0018 0.0045 0.0095
Mycobacterium ulcerans bifunctional N-acetylglucosamine-1-phosphate uridyltransferase/glucosamine-1-phosphate acetyltransferase 0.0609 0.4119 1
Brugia malayi jmjC domain containing protein 0.0105 0.0645 0.2173
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0018 0.0045 0.0121
Mycobacterium tuberculosis Probable oxidoreductase 0.0332 0.221 0.5361
Echinococcus granulosus tyrosyl DNA phosphodiesterase 1 0.0071 0.041 0.041
Trypanosoma brucei DNA polymerase kappa, putative 0.0074 0.0433 0.099
Giardia lamblia NADH oxidase lateral transfer candidate 0.0045 0.0234 0.1137
Trypanosoma brucei polo-like protein kinase 0.0101 0.0621 0.1425
Echinococcus granulosus fetal alzheimer antigen falz 0.0026 0.01 0.01
Brugia malayi Tyrosyl-DNA phosphodiesterase family protein 0.0071 0.041 0.1382
Trichomonas vaginalis dihydroorotate dehydrogenase, putative 0.0012 0.0004 0.00000040069
Echinococcus multilocularis glutamate synthase 0.0012 0.0004 0.0004
Echinococcus granulosus aldehyde dehydrogenase mitochondrial 0.0129 0.0808 0.0808
Onchocerca volvulus Protein ultraspiracle homolog 0.0022 0.0071 0.021
Trichomonas vaginalis alpha-glucosidase, putative 0.0039 0.0189 0.0547
Trypanosoma brucei DNA polymerase kappa, putative 0.0126 0.0789 0.1814
Onchocerca volvulus 0.0025 0.0092 0.0271
Plasmodium falciparum conserved Plasmodium protein, unknown function 0.0024 0.0088 0.0709
Brugia malayi jmjC domain containing protein 0.0027 0.0107 0.036
Echinococcus multilocularis pyridine nucleotide disulfide oxidoreductase 0.0012 0.0004 0.0004
Loa Loa (eye worm) hypothetical protein 0.0101 0.0618 0.2083
Echinococcus granulosus sulfide:quinone oxidoreductase 0.0012 0.0004 0.0004
Echinococcus granulosus suppression of tumorigenicity 18 protein 0.0115 0.0714 0.0714
Trichomonas vaginalis chromodomain-helicase-DNA-binding protein, putative 0.0024 0.0088 0.0247
Leishmania major 4-coumarate:coa ligase-like protein 0.0025 0.0092 0.0202
Echinococcus multilocularis SUMO activating enzyme subunit 1 0.005 0.0268 0.0268
Trichomonas vaginalis conserved hypothetical protein 0.0024 0.0088 0.0247
Echinococcus granulosus cpg binding protein 0.0035 0.016 0.016
Onchocerca volvulus Uncharacterized family 31 glucosidase KIAA1161 homolog 0.0014 0.0021 0.0062
Trypanosoma brucei chrX additional, unordered contigs 0.003 0.013 0.0289
Loa Loa (eye worm) nuclear hormone receptor family member nhr-40 0.0022 0.0071 0.0238
Echinococcus multilocularis lysine specific demethylase 6a 0.0027 0.0107 0.0107
Loa Loa (eye worm) hypothetical protein 0.016 0.1028 0.3465
Trichomonas vaginalis Clan CA, family C1, papain-like cysteine peptidase 0.0018 0.0045 0.0121
Giardia lamblia Histone acetyltransferase GCN5 0.0042 0.0211 0.1022
Mycobacterium leprae PROBABLE NADH DEHYDROGENASE NDH 0.0299 0.1981 0.4803
Leishmania major hypothetical protein, conserved 0.0016 0.0035 0.007
Entamoeba histolytica hypothetical protein 0.0024 0.0088 0.0413
Schistosoma mansoni apoptosis regulator bax 0.0089 0.0535 0.0534
Treponema pallidum 4'-phosphopantetheinyl transferase 0.005 0.0263 0.1279
Trypanosoma cruzi DNA polymerase eta, putative 0.0084 0.0502 0.1149
Onchocerca volvulus Cathepsin L homolog 0.0018 0.0045 0.0134
Echinococcus multilocularis serine:threonine protein kinase PLK1 0.0101 0.0621 0.0621
Echinococcus granulosus bloom syndrome protein 0.0047 0.0246 0.0246
Schistosoma mansoni mixed-lineage leukemia protein mll 0.0068 0.0389 0.0388
Trichomonas vaginalis ap endonuclease, putative 0.002 0.0061 0.0166
Trichomonas vaginalis DNA helicase recq, putative 0.0035 0.0163 0.047
Leishmania major cathepsin L-like protease 0.0069 0.0394 0.09
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0069 0.0394 0.09
Plasmodium falciparum dihydrolipoyl dehydrogenase, mitochondrial 0.0045 0.0234 0.1951
Entamoeba histolytica glutamate synthase beta subunit, putative 0.0012 0.0004 0.00000067057
Trypanosoma cruzi hypothetical protein, conserved 0.003 0.013 0.0289
Trichomonas vaginalis disulfide oxidoreductase, putative 0.0012 0.0004 0.00000040069
Trichomonas vaginalis fructose-bisphosphate aldolase, putative 0.0305 0.2025 0.5975
Trichomonas vaginalis conserved hypothetical protein 0.0024 0.0088 0.0247
Loa Loa (eye worm) PHD-finger family protein 0.0031 0.0137 0.0462
Plasmodium falciparum phd finger protein, putative 0.0031 0.0137 0.1129
Mycobacterium leprae PROBABLE FATTY-ACID-CoA LIGASE FADD7 (FATTY-ACID-CoA SYNTHETASE) (FATTY-ACID-CoA SYNTHASE) 0.0025 0.0092 0.0213
Trichomonas vaginalis alpha-glucosidase, putative 0.0014 0.0021 0.0049
Schistosoma mansoni terminal deoxycytidyl transferase 0.0097 0.0592 0.0592
Brugia malayi ATP-dependent DNA helicase, RecQ family protein 0.0032 0.0142 0.0476
Echinococcus multilocularis tyrosyl DNA phosphodiesterase 1 0.0071 0.041 0.041
Onchocerca volvulus 0.0016 0.0029 0.0086
Trypanosoma cruzi 2,4-dihydroxyhept-2-ene-1,7-dioic acid aldolase, putative 0.0026 0.0103 0.0227
Brugia malayi Cathepsin L-like cysteine proteinase 0.0012 0.0004 0.0013
Trypanosoma brucei peptidyl-prolyl cis-trans isomerase/rotamase, putative 0.0035 0.0163 0.0366
Onchocerca volvulus 0.0016 0.0029 0.0086
Mycobacterium ulcerans acyl-CoA synthetase 0.0025 0.0092 0.0213
Loa Loa (eye worm) jmjC domain-containing protein 0.0027 0.0107 0.036
Loa Loa (eye worm) hypothetical protein 0.0027 0.0107 0.036
Trypanosoma brucei DNA polymerase kappa, putative 0.0074 0.0433 0.099
Trichomonas vaginalis flap endonuclease-1, putative 0.0028 0.0114 0.0325
Schistosoma mansoni cpg binding protein 0.0031 0.0134 0.0134
Trichomonas vaginalis dihydroorotate dehydrogenase, putative 0.0012 0.0004 0.00000040069
Echinococcus granulosus dna polymerase kappa 0.0126 0.0789 0.0789
Loa Loa (eye worm) hypothetical protein 0.0024 0.0088 0.0295
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0018 0.0045 0.0121
Brugia malayi Thioredoxin reductase 0.0131 0.0824 0.2778
Loa Loa (eye worm) hypothetical protein 0.0017 0.0037 0.0124
Loa Loa (eye worm) hypothetical protein 0.0014 0.0018 0.006
Echinococcus granulosus dihydrolipoamide dehydrogenase 0.0045 0.0234 0.0234
Toxoplasma gondii ImpB/MucB/SamB family protein 0.003 0.013 0.1063
Schistosoma mansoni gabp alpha 0.0078 0.0458 0.0457
Echinococcus multilocularis inositol monophosphatase 1 0.004 0.0195 0.0195
Entamoeba histolytica pyridine nucleotide-disulfide oxidoreductase family protein 0.0012 0.0004 0.00000067057
Trichomonas vaginalis protein kinase inhibitor, putative 0.0066 0.0375 0.1097
Toxoplasma gondii ATP-dependent DNA helicase, RecQ family protein 0.0032 0.0142 0.1165
Brugia malayi CXXC zinc finger family protein 0.0031 0.0134 0.0451
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0018 0.0045 0.0121
Brugia malayi PHD-finger family protein 0.0032 0.0144 0.0485
Schistosoma mansoni sumo-1-activating enzyme E1a 0.005 0.0268 0.0268
Leishmania major PAS-domain containing phosphoglycerate kinase, putative 0.0067 0.0384 0.0878
Loa Loa (eye worm) apoptosis regulator protein 0.0089 0.0535 0.1802
Trichomonas vaginalis CAMK family protein kinase 0.0101 0.0621 0.1824
Plasmodium vivax heterochromatin protein 1, putative 0.0024 0.0088 0.0709
Brugia malayi Bromodomain containing protein 0.0045 0.0231 0.0779
Schistosoma mansoni ap endonuclease 0.002 0.0061 0.006
Brugia malayi chromobox protein homolog 3 0.0083 0.0492 0.1657
Echinococcus granulosus muscleblind protein 0.016 0.1028 0.1028
Echinococcus multilocularis phd:f box containing protein 0.0027 0.0107 0.0107
Brugia malayi Associated with TFs and helicases family protein 0.0024 0.0088 0.0295
Trypanosoma cruzi phosphoglycerate kinase, putative 0.0067 0.0384 0.0878
Brugia malayi Glycosyl hydrolases family 31 protein 0.0039 0.0189 0.0636
Trypanosoma cruzi DNA polymerase beta thumb, putative 0.009 0.0542 0.1241
Trypanosoma cruzi dihydrolipoamide dehydrogenase, putative 0.0045 0.0234 0.0531
Schistosoma mansoni sulfide quinone reductase 0.0012 0.0004 0.0004
Echinococcus multilocularis methyl CpG binding domain protein 2 0.0018 0.0048 0.0047
Echinococcus granulosus flap endonuclease 1 0.0028 0.0114 0.0114
Brugia malayi Nuclear hormone receptor family member nhr-41 0.0022 0.0071 0.0238
Trichomonas vaginalis alpha-glucosidase, putative 0.0014 0.0021 0.0049
Brugia malayi alpha keto acid dehydrogenase complex, E3 component, lipoamide dehydrogenase 0.0033 0.0151 0.0508
Schistosoma mansoni sulfide quinone reductase 0.0012 0.0004 0.0004
Loa Loa (eye worm) pyridine nucleotide-disufhide oxidoreductase 0.0012 0.0004 0.0013
Mycobacterium tuberculosis Putative ferredoxin reductase 0.0299 0.1981 0.4803
Brugia malayi aminoadipate-semialdehyde dehydrogenase-phosphopantetheinyl transferase 0.0176 0.1136 0.3828
Mycobacterium tuberculosis Dihydrolipoamide dehydrogenase LpdC (lipoamide reductase (NADH)) (lipoyl dehydrogenase) (dihydrolipoyl dehydrogenase) (diaphoras 0.0332 0.221 0.5361
Trypanosoma cruzi 3-phosphoglycerate kinase, glycosomal 0.0067 0.0384 0.0878
Entamoeba histolytica chromodomain-helicase-DNA-binding protein, putative 0.0024 0.0088 0.0413
Echinococcus multilocularis PHD finger protein rhinoceros 0.0031 0.0137 0.0137
Trichomonas vaginalis rotamase, putative 0.0036 0.0169 0.0486
Echinococcus granulosus EGFP:Bcl2 fusion protein 0.0089 0.0535 0.0534
Trypanosoma cruzi mitochondrial DNA polymerase beta-PAK, putative 0.009 0.0542 0.1241
Entamoeba histolytica dihydropyrimidine dehydrogenase, putative 0.0012 0.0004 0.00000067057
Schistosoma mansoni chromobox protein-related (chromobox 1) (heterochromatin 1) 0.0024 0.0088 0.0087
Schistosoma mansoni glutamate synthase 0.0012 0.0004 0.0004
Trypanosoma cruzi glycosyl hydrolase-like protein, putative 0.0014 0.0021 0.0039
Entamoeba histolytica cysteine proteinase, putative 0.0018 0.0045 0.0203
Trypanosoma cruzi cysteine peptidase, putative 0.0069 0.0394 0.09
Plasmodium falciparum SUMO-activating enzyme subunit 2 0.0033 0.015 0.1233
Loa Loa (eye worm) mbt repeat family protein 0.0101 0.0618 0.2083
Echinococcus multilocularis zinc finger protein 0.0027 0.0105 0.0104
Schistosoma mansoni phosphatidylserine receptor 0.0027 0.0107 0.0107
Trichomonas vaginalis myo inositol monophosphatase, putative 0.004 0.0195 0.0564
Echinococcus granulosus COUP TF:Svp nuclear hormone receptor 0.0022 0.0071 0.0071
Brugia malayi Muscleblind-like protein 0.016 0.1028 0.3465
Loa Loa (eye worm) histone methyltransferase 0.0012 0.0003 0.0009
Entamoeba histolytica cysteine protease, putative 0.0018 0.0045 0.0203
Mycobacterium ulcerans hypothetical protein 0.0112 0.0691 0.1669
Leishmania major dihydrolipoamide dehydrogenase, putative 0.0045 0.0234 0.0531
Echinococcus granulosus Bcl 2 ous antagonist:killer 0.0089 0.0535 0.0534
Loa Loa (eye worm) hypothetical protein 0.0018 0.0049 0.0163
Echinococcus multilocularis Transcription factor, JmjC domain containing protein 0.0166 0.1064 0.1064
Toxoplasma gondii 'chromo' (CHRromatin Organization MOdifier) domain-containing protein 0.0024 0.0088 0.0709
Trypanosoma brucei DNA polymerase kappa, putative 0.0126 0.0789 0.1814
Brugia malayi Cathepsin L-like precursor 0.0018 0.0045 0.0152
Echinococcus multilocularis Bcl 2 ous antagonist:killer 0.0089 0.0535 0.0534
Mycobacterium tuberculosis Conserved hypothetical protein 0.0337 0.2245 0.5445
Schistosoma mansoni nuclear receptor 2DBD-gamma 0.0022 0.0071 0.0071
Echinococcus multilocularis bromodomain adjacent to zinc finger domain 0.007 0.0402 0.0402
Mycobacterium ulcerans fatty-acid-CoA ligase 0.0025 0.0092 0.0213
Schistosoma mansoni hypothetical protein 0.0135 0.0854 0.0854
Mycobacterium tuberculosis holo-[acyl-carrier protein] synthase AcpS (holo-ACP synthase) (CoA:APO-[ACP]pantetheinephosphotransferase) (CoA:APO-[acyl-carrie 0.005 0.0263 0.0628
Giardia lamblia DNA damage repair protein 0.003 0.013 0.062
Schistosoma mansoni tyrosyl-DNA phosphodiesterase 0.0071 0.041 0.041
Trichomonas vaginalis chromodomain-helicase-DNA-binding protein, putative 0.0031 0.0136 0.039
Trypanosoma cruzi mitochondrial DNA polymerase beta, putative 0.064 0.4332 1
Trichomonas vaginalis chromodomain helicase DNA binding protein, putative 0.0031 0.0136 0.039
Onchocerca volvulus 0.0018 0.0045 0.0134
Trypanosoma cruzi ISWI complex protein 0.0016 0.0035 0.007
Echinococcus multilocularis Chromo domain 0.0024 0.0088 0.0087
Schistosoma mansoni scm-relatedprotein containing 4 mbt domains (sfmbt) 0.0101 0.0618 0.0618
Onchocerca volvulus 0.0065 0.0368 0.1088
Echinococcus multilocularis polycomb protein SCMH1 0.0101 0.0618 0.0618
Trypanosoma cruzi cysteine peptidase, clan CA, family C1, cathepsin L-like, putative 0.0063 0.0353 0.0805
Plasmodium vivax dihydrolipoyl dehydrogenase, mitochondrial, putative 0.0045 0.0234 0.1951
Schistosoma mansoni glutaminase 0.0294 0.1946 0.1946
Echinococcus multilocularis nuclear receptor 2DBD gamma 0.0022 0.0071 0.0071
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0018 0.0045 0.0121
Echinococcus granulosus jumonji domain containing 1A 0.0027 0.0107 0.0107
Trichomonas vaginalis CAMK family protein kinase 0.0101 0.0621 0.1824
Trichomonas vaginalis Citrate lyase beta chain, putative 0.0026 0.0103 0.0291
Plasmodium vivax holo-[acyl-carrier-protein] synthase, putative 0.005 0.0263 0.2195
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0069 0.0394 0.09
Brugia malayi Ets-domain containing protein 0.0078 0.0458 0.1543
Leishmania major cathepsin L-like protease 0.0018 0.0045 0.0095
Echinococcus multilocularis ubiquitin carboxyl terminal hydrolase 8 0.0039 0.0187 0.0187
Toxoplasma gondii 'chromo' (CHRromatin Organization MOdifier) domain-containing protein 0.0024 0.0088 0.0709
Loa Loa (eye worm) hypothetical protein 0.0025 0.0092 0.0309
Leishmania major cathepsin L-like protease 0.0018 0.0045 0.0095
Echinococcus granulosus ATP dependent DNA helicase Q1 0.0032 0.0142 0.0141
Trypanosoma cruzi DNA polymerase kappa, putative 0.0126 0.0789 0.1814
Schistosoma mansoni aldehyde dehydrogenase 0.0129 0.0808 0.0808
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0069 0.0394 0.09
Trypanosoma brucei DNA polymerase IV, putative 0.0126 0.0789 0.1814
Mycobacterium ulcerans citrate lyase beta subunit, CitE_2 0.0026 0.0103 0.0239
Trichomonas vaginalis chromodomain helicase DNA binding protein, putative 0.0031 0.0136 0.039
Trichomonas vaginalis chromobox protein, putative 0.0148 0.0939 0.2764
Trichomonas vaginalis conserved hypothetical protein 0.0059 0.0325 0.0949
Loa Loa (eye worm) hypothetical protein 0.0188 0.1221 0.4115
Brugia malayi Nuclear hormone receptor-like 1 0.0022 0.0071 0.0238
Loa Loa (eye worm) acetyltransferase 0.0158 0.1013 0.3414
Trichomonas vaginalis conserved hypothetical protein 0.0083 0.0492 0.1441
Schistosoma mansoni DNA polymerase IV / kappa 0.003 0.013 0.0129
Trichomonas vaginalis chromodomain helicase DNA binding protein, putative 0.0031 0.0136 0.039
Schistosoma mansoni hypothetical protein 0.0618 0.4184 0.4184
Trypanosoma cruzi polo-like protein kinase, putative 0.0101 0.0621 0.1425
Loa Loa (eye worm) hypothetical protein 0.0024 0.0088 0.0295
Mycobacterium tuberculosis Probable fructose-bisphosphate aldolase Fba 0.0149 0.0949 0.2295
Leishmania major cysteine peptidase A (CPA) 0.0018 0.0045 0.0095
Plasmodium vivax hypothetical protein, conserved 0.0031 0.0137 0.1129
Trypanosoma cruzi dihydrolipoyl dehydrogenase, putative 0.0045 0.0234 0.0531
Brugia malayi Pyridine nucleotide-disulphide oxidoreductase family protein 0.0012 0.0004 0.0013
Echinococcus granulosus bromodomain adjacent to zinc finger domain 0.0039 0.0187 0.0187
Onchocerca volvulus 0.0018 0.0045 0.0134
Echinococcus granulosus MAM 0.0017 0.0037 0.0037
Trypanosoma cruzi JmjC domain, hydroxylase, putative 0.0027 0.0107 0.0238
Schistosoma mansoni cathepsin F (C01 family) 0.0012 0.0004 0.0004
Loa Loa (eye worm) hypothetical protein 0.0065 0.0368 0.1241
Mycobacterium tuberculosis Conserved hypothetical protein 0.0097 0.0592 0.1429
Toxoplasma gondii ThiF family protein 0.0033 0.015 0.1233
Trypanosoma brucei DNA polymerase kappa, putative 0.0104 0.0641 0.1471
Echinococcus multilocularis flap endonuclease 1 0.0028 0.0114 0.0114
Echinococcus multilocularis sulfide:quinone oxidoreductase 0.0012 0.0004 0.0004
Mycobacterium ulcerans exodeoxyribonuclease III protein XthA 0.002 0.0061 0.0137
Onchocerca volvulus 0.0031 0.0134 0.0396
Brugia malayi AMP-binding enzyme family protein 0.0025 0.0092 0.0309
Echinococcus granulosus lysosomal alpha glucosidase 0.0175 0.1128 0.1128
Loa Loa (eye worm) hypothetical protein 0.0024 0.0088 0.0295
Trypanosoma brucei mitochondrial DNA polymerase beta-PAK 0.0303 0.2009 0.4632
Trypanosoma cruzi DNA polymerase kappa, putative 0.0126 0.0789 0.1814
Echinococcus granulosus ubiquitin specific protease 41 0.0039 0.0187 0.0187
Brugia malayi Glycosyl hydrolases family 31 protein 0.0014 0.0021 0.007
Loa Loa (eye worm) cysteine protease 0.0018 0.0045 0.0152
Leishmania major peptidyl-prolyl cis-trans isomerase/rotamase, putative,PPIase, putative 0.0035 0.0163 0.0366
Schistosoma mansoni jumonji/arid domain-containing protein 0.0105 0.0645 0.0644
Leishmania major DNA polymerase eta, putative 0.0151 0.0964 0.2218
Brugia malayi Ligand-binding domain of nuclear hormone receptor family protein 0.0022 0.0071 0.0238
Entamoeba histolytica acetyltransferase, GNAT family 0.0042 0.0211 0.1022
Brugia malayi Nuclear hormone receptor family member nhr-19 0.0022 0.0071 0.0238
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0069 0.0394 0.09
Plasmodium vivax hypothetical protein, conserved 0.0012 0.0005 0.0004
Schistosoma mansoni inositol monophosphatase 0.004 0.0195 0.0195
Schistosoma mansoni cathepsin F (C01 family) 0.0018 0.0045 0.0045
Schistosoma mansoni RAR-like nuclear receptor 0.0022 0.0071 0.0071
Schistosoma mansoni DNA polymerase eta 0.0151 0.0964 0.0964
Loa Loa (eye worm) flap endonuclease-1 0.0028 0.0114 0.0384
Brugia malayi Nuclear hormone receptor family member nhr-25 0.0022 0.0071 0.0238
Echinococcus multilocularis cathepsin L cysteine protease 0.0018 0.0045 0.0045
Schistosoma mansoni ubiquitously transcribed sex (X/Y) chromosome tetratricopeptide repeat protein-related 0.0027 0.0107 0.0107
Echinococcus granulosus endonuclease exonuclease phosphatase 0.0402 0.2695 0.2694
Echinococcus multilocularis SUMO activating enzyme subunit 2 0.0033 0.015 0.0149
Loa Loa (eye worm) nuclear hormone receptor family member nhr-14 0.0022 0.0071 0.0238
Schistosoma mansoni hypothetical protein 0.0012 0.0004 0.0004
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0069 0.0394 0.09
Loa Loa (eye worm) hypothetical protein 0.0141 0.0891 0.3005
Onchocerca volvulus 0.0022 0.0071 0.021
Echinococcus granulosus inositol monophosphatase 1 0.004 0.0195 0.0195
Giardia lamblia Flap structure-specific endonuclease 0.0028 0.0114 0.0544
Mycobacterium ulcerans aldehyde dehydrogenase 0.0129 0.0808 0.1953
Leishmania major hypothetical protein, conserved 0.0027 0.0107 0.0238
Schistosoma mansoni sumo-1-activating enzyme E1a 0.0046 0.0236 0.0236
Echinococcus granulosus SAM and MBT domain containing protein 0.0101 0.0618 0.0618
Leishmania major ATP-dependent DEAD/H DNA helicase recQ, putative 0.0035 0.0163 0.0367
Echinococcus multilocularis microtubule associated protein 2 0.1461 1 1
Leishmania major DNA polymerase eta, putative 0.0084 0.0502 0.1149
Echinococcus granulosus Peptidase C19 ubiquitin carboxyl terminal hydrolase 2 0.0039 0.0187 0.0187
Schistosoma mansoni blooms syndrome DNA helicase 0.0031 0.0134 0.0133
Plasmodium vivax ATP-dependent DNA helicase Q1, putative 0.0016 0.0029 0.0212
Echinococcus multilocularis Mitotic checkpoint protein PRCC, C terminal 0.0135 0.0854 0.0854
Schistosoma mansoni methyl-cpg binding protein mbd 0.0018 0.0048 0.0047
Onchocerca volvulus 0.0016 0.0029 0.0086
Entamoeba histolytica NAD(FAD)-dependent dehydrogenase, putative 0.0012 0.0004 0.00000067057
Trichomonas vaginalis glutaminase, putative 0.0294 0.1946 0.5744
Loa Loa (eye worm) hypothetical protein 0.0016 0.0029 0.0096
Mycobacterium tuberculosis Probable fatty-acid-CoA ligase FadD5 (fatty-acid-CoA synthetase) (fatty-acid-CoA synthase) 0.0017 0.0042 0.0091
Plasmodium falciparum ATP-dependent DNA helicase Q1 0.0032 0.0142 0.1165
Mycobacterium tuberculosis NAD(P)H quinone reductase LpdA 0.0332 0.221 0.5361
Echinococcus multilocularis apoptosis inducing factor 1 mitochondrial 0.0012 0.0004 0.0004
Mycobacterium tuberculosis Probable fatty-acid-CoA ligase FadD3 (fatty-acid-CoA synthetase) (fatty-acid-CoA synthase) 0.0017 0.0042 0.0091
Trypanosoma cruzi dihydrolipoamide dehydrogenase, putative 0.0045 0.0234 0.0531
Echinococcus granulosus thioredoxin glutathione reductase 0.0132 0.0831 0.0831
Onchocerca volvulus Polycomb protein Sfmbt homolog 0.0101 0.0618 0.1825
Trypanosoma cruzi PAS-domain containing phosphoglycerate kinase, putative 0.0067 0.0384 0.0878
Echinococcus granulosus dnaJ subfamily C 6 0.0066 0.0375 0.0375
Mycobacterium ulcerans long-chain-fatty-acid-CoA ligase 0.0025 0.0092 0.0213
Trypanosoma cruzi peptidyl-prolyl cis-trans isomerase 0.0035 0.0163 0.0366
Echinococcus multilocularis bloom syndrome protein 0.0047 0.0246 0.0246
Trypanosoma brucei dihydrolipoamide dehydrogenase 0.0045 0.0234 0.0531
Trichomonas vaginalis myo inositol monophosphatase, putative 0.004 0.0195 0.0564
Trichomonas vaginalis Clan CA, family C1, papain-like cysteine peptidase 0.0018 0.0045 0.0121
Loa Loa (eye worm) fibroinase 0.0018 0.0045 0.0152
Brugia malayi Nuclear hormone receptor family member nhr-3 0.0022 0.0071 0.0238
Brugia malayi acetyltransferase, GNAT family protein 0.0158 0.1013 0.3414
Brugia malayi Type III restriction enzyme, res subunit family protein 0.0024 0.0088 0.0295
Trypanosoma brucei phosphoglycerate kinase 0.0067 0.0384 0.0878
Loa Loa (eye worm) hypothetical protein 0.0017 0.0037 0.0124
Loa Loa (eye worm) hypothetical protein 0.0089 0.0535 0.1802
Wolbachia endosymbiont of Brugia malayi fructose-1,6-bisphosphatase 0.004 0.0195 0.0463
Trypanosoma cruzi DNA polymerase kappa, putative 0.0126 0.0789 0.1814
Brugia malayi Flap endonuclease-1 0.0028 0.0114 0.0384
Brugia malayi hypothetical protein 0.0024 0.0088 0.0295
Trypanosoma cruzi glycosyl hydrolase-like protein, putative 0.0014 0.0021 0.0039
Plasmodium vivax AP endonuclease (DNA-[apurinic or apyrimidinic site] lyase), putative 0.002 0.0061 0.0478
Plasmodium falciparum DNA repair protein REV1, putative 0.003 0.013 0.1063
Entamoeba histolytica exodeoxyribonuclease III, putative 0.002 0.0061 0.0279
Toxoplasma gondii flap structure-specific endonuclease 1, putative 0.0028 0.0114 0.0933
Loa Loa (eye worm) hypothetical protein 0.0082 0.0488 0.1645
Trichomonas vaginalis conserved hypothetical protein 0.0024 0.0088 0.0247
Trichomonas vaginalis molybdopterin biosynthesis moeb protein, putative 0.0016 0.003 0.0075
Trypanosoma cruzi JmjC domain, hydroxylase, putative 0.0027 0.0107 0.0238
Schistosoma mansoni hypothetical protein 0.0089 0.0535 0.0534
Echinococcus multilocularis jumonji domain containing protein 0.0044 0.0222 0.0221
Echinococcus granulosus histone lysine methyltransferase setb 0.0082 0.0488 0.0488
Schistosoma mansoni FTZ-F1 nuclear receptor-like protein 0.0022 0.0071 0.0071
Echinococcus multilocularis expressed protein 0.0036 0.0169 0.0168
Brugia malayi PHD-finger family protein 0.0014 0.0018 0.006
Leishmania major DNA damage repair protein, putative 0.003 0.013 0.0289
Toxoplasma gondii chromodomain helicase DNA binding protein CHD1/SWI2/SNF2 0.0024 0.0088 0.0709
Brugia malayi Valyl-tRNA synthetase 0.0024 0.0088 0.0295
Loa Loa (eye worm) hypothetical protein 0.0067 0.038 0.128
Trypanosoma cruzi flap endonuclease-1 (FEN-1), putative 0.0028 0.0114 0.0254
Leishmania major mitochondrial DNA polymerase beta 0.064 0.4332 1
Plasmodium falciparum chromodomain-helicase-DNA-binding protein 1 homolog, putative 0.0024 0.0088 0.0709
Trypanosoma cruzi tyrosyl-DNA Phosphodiesterase (Tdp1), putative 0.0071 0.041 0.0938
Trichomonas vaginalis Clan CA, family C19, ubiquitin hydrolase-like cysteine peptidase 0.0039 0.0187 0.0542
Schistosoma mansoni glutamate synthase 0.0012 0.0004 0.0004
Loa Loa (eye worm) hypothetical protein 0.0059 0.0327 0.11
Loa Loa (eye worm) nuclear hormone receptor family member nhr-41 0.0022 0.0071 0.0238
Onchocerca volvulus 0.0012 0.0004 0.0013
Trichomonas vaginalis chromodomain helicase DNA binding protein, putative 0.0027 0.011 0.0313
Trypanosoma brucei dihydrolipoamide dehydrogenase 0.0045 0.0234 0.0531
Onchocerca volvulus 0.0018 0.0045 0.0134
Loa Loa (eye worm) hypothetical protein 0.0022 0.0071 0.0238
Loa Loa (eye worm) fli-1 protein 0.0236 0.155 0.5226
Trichomonas vaginalis conserved hypothetical protein 0.0083 0.0492 0.1441
Mycobacterium tuberculosis Fatty-acid-AMP ligase FadD30 (fatty-acid-AMP synthetase) (fatty-acid-AMP synthase) 0.0018 0.0049 0.0108
Trichomonas vaginalis DNA polymerase eta, putative 0.0126 0.0789 0.2321
Loa Loa (eye worm) jmjC domain-containing protein 0.0105 0.0645 0.2173
Schistosoma mansoni thyroid hormone receptor 0.0157 0.1004 0.1003
Trichomonas vaginalis disulfide oxidoreductase, putative 0.0012 0.0004 0.00000040069
Schistosoma mansoni hypothetical protein 0.0017 0.0037 0.0037
Loa Loa (eye worm) hypothetical protein 0.0027 0.0107 0.036
Schistosoma mansoni hypothetical protein 0.0016 0.0029 0.0029
Echinococcus multilocularis dnaJ subfamily C 6 0.0066 0.0375 0.0375
Trypanosoma cruzi ubiquitin carboxyl-terminal hydrolase, putative 0.0039 0.0187 0.0423
Schistosoma mansoni blooms syndrome DNA helicase 0.0016 0.0034 0.0033
Echinococcus granulosus 5'partial|histone lysine N methyltransferase SETDB2 0.0061 0.0341 0.0341
Trypanosoma cruzi cysteine peptidase, putative 0.0069 0.0394 0.09
Trichomonas vaginalis dihydrolipoamide dehydrogenase, putative 0.0012 0.0004 0.00000040069
Onchocerca volvulus 0.0018 0.0045 0.0134
Brugia malayi Nuclear hormone receptor family member nhr-14 0.0022 0.0071 0.0238
Echinococcus granulosus dna polymerase eta 0.0151 0.0964 0.0964
Echinococcus granulosus histone acetyltransferase MYST2 0.0115 0.0714 0.0714
Loa Loa (eye worm) PHD-finger family protein 0.0022 0.0074 0.0249
Trypanosoma brucei apurinic/apyrimidinic endonuclease, putative 0.002 0.0061 0.013
Echinococcus multilocularis jumonji domain containing 1A 0.0027 0.0107 0.0107
Mycobacterium leprae conserved hypothetical protein 0.005 0.0263 0.0628
Trypanosoma cruzi DNA polymerase eta, putative 0.0151 0.0964 0.2218
Plasmodium falciparum cysteine proteinase falcipain 2b 0.0018 0.0045 0.0348
Loa Loa (eye worm) hypothetical protein 0.0115 0.0714 0.2408
Onchocerca volvulus Steroid hormone receptor family member cnr14 homolog 0.0022 0.0071 0.021
Treponema pallidum exodeoxyribonuclease (exoA) 0.002 0.0061 0.0279
Plasmodium vivax flap endonuclease 1, putative 0.0028 0.0114 0.0933
Echinococcus granulosus cathepsin l1 0.0018 0.0045 0.0045
Loa Loa (eye worm) hypothetical protein 0.0016 0.0029 0.0096
Plasmodium falciparum holo-[acyl-carrier-protein] synthase, putative 0.005 0.0263 0.2195
Trichomonas vaginalis fructose-bisphosphate aldolase, putative 0.0305 0.2025 0.5975
Chlamydia trachomatis phosphoglycerate kinase 0.0183 0.1182 1
Giardia lamblia Endonuclease/Exonuclease/phosphatase 0.002 0.0061 0.0279
Trichomonas vaginalis chromobox protein, putative 0.0024 0.0088 0.0247
Trypanosoma cruzi cysteine peptidase, putative 0.0018 0.0045 0.0095
Trypanosoma brucei hypothetical protein, conserved 0.003 0.013 0.0289
Loa Loa (eye worm) hypothetical protein 0.0076 0.0445 0.15
Schistosoma mansoni chromobox protein 0.0024 0.0088 0.0087
Leishmania major aldehyde dehydrogenase, mitochondrial precursor 0.0129 0.0808 0.1857
Trypanosoma brucei dihydrolipoamide dehydrogenase, point mutation 0.0045 0.0234 0.0531
Echinococcus granulosus apoptosis inducing factor 1 mitochondrial 0.0012 0.0004 0.0004
Trypanosoma brucei DNA polymerase kappa, putative 0.0126 0.0789 0.1814
Trypanosoma cruzi hypothetical protein, conserved 0.0229 0.1497 0.345
Trypanosoma brucei DNA polymerase kappa, putative 0.0074 0.0433 0.099
Trypanosoma brucei flap endonuclease-1 (FEN-1), putative 0.0028 0.0114 0.0254
Trypanosoma brucei tyrosyl-DNA Phosphodiesterase (Tdp1), putative 0.0071 0.041 0.0938
Schistosoma mansoni retinoic acid receptor RXR 0.0022 0.0071 0.0071
Brugia malayi SET domain containing protein 0.0027 0.0109 0.0365
Loa Loa (eye worm) hypothetical protein 0.0183 0.1182 0.3985
Loa Loa (eye worm) programmed cell death 8 0.0012 0.0004 0.0013
Toxoplasma gondii BRCA1 C Terminus (BRCT) domain-containing protein 0.0037 0.0178 0.1478
Trypanosoma brucei ubiquitin-activating enzyme E1, putative 0.0033 0.015 0.0336
Trypanosoma cruzi mitochondrial DNA polymerase beta, putative 0.064 0.4332 1
Mycobacterium tuberculosis Conserved protein 0.0026 0.0103 0.0239
Schistosoma mansoni Tr4/Tr2 (homologue) 0.0022 0.0071 0.0071
Echinococcus granulosus lysine specific demethylase 6a 0.0027 0.0107 0.0107
Brugia malayi Bloom's syndrome protein homolog 0.0047 0.0246 0.0828
Toxoplasma gondii pyruvate dehydrogenase complex subunit PDH-E3II 0.0045 0.0234 0.1951
Echinococcus multilocularis endonuclease exonuclease phosphatase 0.0402 0.2695 0.2694
Schistosoma mansoni gcn5proteinral control of amino-acid synthesis 5-like 2 gcnl2 0.0158 0.1013 0.1012
Trypanosoma brucei DNA polymerase kappa, putative 0.0126 0.0789 0.1814
Trichomonas vaginalis fructose-bisphosphate aldolase, putative 0.0305 0.2025 0.5975
Echinococcus granulosus chromodomain helicase DNA binding protein 4 0.0028 0.0114 0.0114
Brugia malayi Apoptosis regulator proteins, Bcl-2 family protein 0.0089 0.0535 0.1802
Echinococcus multilocularis ecdysone induced protein 78C 0.0022 0.0071 0.0071
Echinococcus multilocularis dihydropyrimidine dehydrogenase (NADP+) 0.0012 0.0004 0.0004
Echinococcus multilocularis histone acetyltransferase MYST2 0.0115 0.0714 0.0714
Toxoplasma gondii histone lysine demethylase JMJD6a 0.0027 0.0107 0.0873
Loa Loa (eye worm) glycosyl hydrolase family 31 protein 0.0175 0.1128 0.3804
Loa Loa (eye worm) hypothetical protein 0.0012 0.0004 0.0013
Trypanosoma brucei ubiquitin carboxyl-terminal hydrolase, putative 0.0039 0.0187 0.0423
Schistosoma mansoni rab geranylgeranyl transferase alpha subunit 0.0097 0.0592 0.0592
Leishmania major 2-oxoglutarate dehydrogenase, e3 component, lipoamidedehydrogenase-like protein 0.0045 0.0234 0.0531
Echinococcus granulosus nuclear receptor 2DBD gamma 0.0022 0.0071 0.0071
Entamoeba histolytica glycosyl hydrolase, family 31 protein 0.0039 0.0189 0.0915
Trichomonas vaginalis chromobox protein, putative 0.0024 0.0088 0.0247
Trichomonas vaginalis alpha-glucosidase, putative 0.0014 0.0021 0.0049
Trichomonas vaginalis conserved hypothetical protein 0.0059 0.0325 0.0949
Schistosoma mansoni alpha-glucosidase 0.0151 0.096 0.096
Plasmodium vivax hypothetical protein, conserved 0.0024 0.0088 0.0709
Schistosoma mansoni hypothetical protein 0.0439 0.2952 0.2951
Brugia malayi jmjC domain containing protein 0.0027 0.0107 0.036
Schistosoma mansoni chromobox protein 0.0024 0.0088 0.0087
Treponema pallidum ATP-dependent DNA helicase 0.0016 0.0034 0.0145
Giardia lamblia DINP protein human, muc B family 0.0104 0.0641 0.3152
Brugia malayi Phosphoglycerate kinase 0.0183 0.1182 0.3985
Schistosoma mansoni hypothetical protein 0.0022 0.0074 0.0074
Echinococcus multilocularis fetal alzheimer antigen, falz 0.0026 0.01 0.01
Loa Loa (eye worm) hypothetical protein 0.0022 0.0071 0.0238
Plasmodium vivax dihydrolipoyl dehydrogenase, apicoplast, putative 0.0045 0.0234 0.1951
Mycobacterium tuberculosis Probable citrate (pro-3S)-lyase (beta subunit) CitE (citrase) (citratase) (citritase) (citridesmolase) (citrase aldolase) 0.0026 0.0103 0.0239
Brugia malayi Cathepsin L-like precursor 0.0012 0.0004 0.0013
Wolbachia endosymbiont of Brugia malayi 4'-phosphopantetheinyl transferase 0.005 0.0263 0.0628
Loa Loa (eye worm) hypothetical protein 0.0024 0.0088 0.0295
Brugia malayi glutaminase DH11.1 0.0294 0.1946 0.6563
Entamoeba histolytica disulphide oxidoreductase, putative 0.0012 0.0004 0.00000067057
Mycobacterium ulcerans hypothetical protein 0.0112 0.0691 0.1669
Mycobacterium leprae Probable phosphoglycerate kinase Pgk 0.0183 0.1182 0.2862
Trichomonas vaginalis set domain proteins, putative 0.0502 0.3386 1
Schistosoma mansoni aminoadipate-semialdehyde dehydrogenase 0.0176 0.1136 0.1135
Trichomonas vaginalis Clan CA, family C1, papain-like cysteine peptidase 0.0018 0.0045 0.0121
Mycobacterium tuberculosis Conserved hypothetical protein 0.0112 0.0691 0.1669
Schistosoma mansoni chromodomain helicase DNA binding protein 0.0028 0.0114 0.0114
Plasmodium falciparum acyl-CoA synthetase 0.0018 0.0049 0.0377
Mycobacterium ulcerans dihydrolipoamide dehydrogenase 0.0045 0.0234 0.0558
Plasmodium vivax SUMO-activating enzyme subunit 2, putative 0.0033 0.015 0.1233
Loa Loa (eye worm) hypothetical protein 0.0071 0.0408 0.1374
Brugia malayi Fli-1 protein 0.0236 0.155 0.5226
Trypanosoma cruzi polo-like protein kinase, putative 0.0101 0.0621 0.1425
Echinococcus granulosus chromodomain helicase DNA binding protein 1 0.0024 0.0088 0.0087
Echinococcus granulosus dnaJ subfamily B 0.0439 0.2952 0.2951
Echinococcus granulosus cathepsin L cysteine proteinase 0.0018 0.0045 0.0045
Entamoeba histolytica acyl-CoA synthetase, putative 0.0025 0.0092 0.0434
Trichomonas vaginalis chromobox protein, putative 0.0148 0.0939 0.2764
Brugia malayi Pin1-type peptidyl-prolyl cis-trans isomerase, BmPin1 0.0036 0.0169 0.0568
Brugia malayi AMP-binding enzyme family protein 0.0025 0.0092 0.0309
Wolbachia endosymbiont of Brugia malayi phosphoglycerate kinase 0.0183 0.1182 0.2862
Loa Loa (eye worm) nuclear hormone receptor family member nhr-1 0.0022 0.0071 0.0238
Echinococcus multilocularis L aminoadipate semialdehyde 0.0176 0.1136 0.1135
Trichomonas vaginalis disulfide oxidoreductase, putative 0.0012 0.0004 0.00000040069
Echinococcus granulosus GA binding protein alpha chain 0.0078 0.0458 0.0457
Plasmodium vivax SET domain protein, putative 0.0064 0.0362 0.3036
Loa Loa (eye worm) glycosyl hydrolase family 31 protein 0.0039 0.0189 0.0636
Giardia lamblia Kinase, PLK 0.0101 0.0621 0.3053
Mycobacterium leprae Probable UDP-N-acetylglucosamine pyrophosphorylase GlmU 0.0609 0.4119 1
Leishmania major alpha glucosidase II subunit, putative 0.0039 0.0189 0.0427
Loa Loa (eye worm) hypothetical protein 0.0022 0.0071 0.0238
Echinococcus granulosus nuclear receptor 2DBD gamma 0.0022 0.0071 0.0071
Trichomonas vaginalis chromodomain-helicase-DNA-binding protein, putative 0.0031 0.0136 0.039
Echinococcus granulosus glutamate synthase 0.0012 0.0004 0.0004
Mycobacterium ulcerans long-chain fatty-acid CoA ligase 0.0025 0.0092 0.0213
Trichomonas vaginalis neutral alpha-glucosidase ab precursor, putative 0.0039 0.0189 0.0547
Loa Loa (eye worm) hypothetical protein 0.0025 0.0092 0.0309
Giardia lamblia Ubiquitin carboxyl-terminal hydrolase 4 0.0039 0.0187 0.0906
Echinococcus granulosus Mitotic checkpoint protein PRCC C terminal 0.0135 0.0854 0.0854
Leishmania major hypothetical protein, conserved 0.0229 0.1497 0.345
Mycobacterium ulcerans dihydrolipoamide dehydrogenase, LpdB 0.0045 0.0234 0.0558
Trypanosoma brucei phosphoglycerate kinase 0.0183 0.1182 0.2721
Brugia malayi exodeoxyribonuclease III family protein 0.002 0.0061 0.0203
Echinococcus multilocularis Chromobox protein 3 0.0024 0.0088 0.0087
Toxoplasma gondii glycosyl hydrolase, family 31 protein 0.0039 0.0189 0.1569
Mycobacterium ulcerans glutaminase 0.0294 0.1946 0.472
Loa Loa (eye worm) ThiF family protein 0.0033 0.015 0.0503
Echinococcus granulosus zinc finger protein 0.0027 0.0105 0.0104
Trichomonas vaginalis maltase-glucoamylase, putative 0.0039 0.0189 0.0547
Brugia malayi Ubiquitin carboxyl-terminal hydrolase family protein 0.0039 0.0187 0.0631
Leishmania major apurinic/apyrimidinic endonuclease-redox protein 0.002 0.0061 0.013
Trypanosoma cruzi mitochondrial DNA polymerase beta-PAK, putative 0.0303 0.2009 0.4632
Onchocerca volvulus 0.0016 0.0029 0.0086
Echinococcus multilocularis muscleblind protein 0.016 0.1028 0.1028
Echinococcus multilocularis ATP dependent DNA helicase Q1 0.0032 0.0142 0.0141
Trichomonas vaginalis mercuric reductase, putative 0.0045 0.0234 0.068
Trypanosoma cruzi ATP-dependent DEAD/H DNA helicase recQ, putative 0.0016 0.0034 0.0068
Toxoplasma gondii aldehyde dehydrogenase 0.0129 0.0808 0.6824
Loa Loa (eye worm) hypothetical protein 0.0018 0.0049 0.0163
Schistosoma mansoni acetyl-CoA C-acetyltransferase 0.0026 0.01 0.01
Trypanosoma brucei unspecified product 0.0067 0.0384 0.0877
Onchocerca volvulus 0.0024 0.0088 0.0259
Echinococcus multilocularis JmjC domain containing protein 4 0.0027 0.0107 0.0107
Toxoplasma gondii phosphoglycerate kinase PGKI 0.0183 0.1182 1
Onchocerca volvulus Cathepsin L homolog 0.0018 0.0045 0.0134
Plasmodium vivax JmjC domain containing protein 0.0027 0.0107 0.0873
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0018 0.0045 0.0121
Mycobacterium ulcerans acyl-CoA synthetase 0.0025 0.0092 0.0213
Echinococcus multilocularis cysteine protease 0.0018 0.0045 0.0045
Leishmania major mitochondrial DNA polymerase beta-PAK, putative 0.0303 0.2009 0.4632
Schistosoma mansoni rotamase 0.0036 0.0169 0.0168
Echinococcus granulosus NADPH:adrenodoxin oxidoreductase 0.0012 0.0004 0.0004
Trichomonas vaginalis DNA helicase recq, putative 0.0047 0.0246 0.0715
Brugia malayi Pyridine nucleotide-disulphide oxidoreductase, dimerisation domain containing protein 0.0033 0.0151 0.0508
Brugia malayi Bromodomain containing protein 0.0086 0.0515 0.1737
Schistosoma mansoni thyroid hormone receptor 0.0157 0.1004 0.1003
Schistosoma mansoni phosphoglycerate kinase 0.0183 0.1182 0.1182
Entamoeba histolytica serine/threonine protein kinase, putative 0.0101 0.0621 0.3053
Brugia malayi Phosphoglycerate kinase 0.0067 0.0384 0.1294
Echinococcus granulosus DNA apurinic or apyrimidinic site lyase 0.002 0.0061 0.006
Plasmodium falciparum SUMO-activating enzyme subunit 1 0.005 0.0268 0.2241
Mycobacterium tuberculosis Probable soluble pyridine nucleotide transhydrogenase SthA (STH) (NAD(P)(+) transhydrogenase [B-specific]) (nicotinamide nucleot 0.0045 0.0234 0.0558
Trichomonas vaginalis Clan CA, family C19, ubiquitin hydrolase-like cysteine peptidase 0.0039 0.0187 0.0542
Echinococcus multilocularis peregrin 0.0038 0.0181 0.0181
Trichomonas vaginalis dihydropyrimidine dehydrogenase, putative 0.0012 0.0004 0.00000040069
Echinococcus granulosus dihydropyrimidine dehydrogenase NADP 0.0012 0.0004 0.0004
Brugia malayi Cathepsin L-like precursor 0.0018 0.0045 0.0152
Plasmodium falciparum ADP-dependent DNA helicase RecQ 0.0044 0.0224 0.1868
Loa Loa (eye worm) hypothetical protein 0.0012 0.0004 0.0013
Trypanosoma brucei DNA polymerase kappa, putative 0.0126 0.0789 0.1814
Loa Loa (eye worm) hypothetical protein 0.0012 0.0004 0.0013
Schistosoma mansoni jumonji domain containing protein 0.0145 0.0919 0.0919
Plasmodium falciparum cysteine proteinase falcipain 3 0.0018 0.0045 0.0348
Brugia malayi photoreceptor-specific nuclear receptor 0.0022 0.0071 0.0238
Brugia malayi dihydrolipoyl dehydrogenase, mitochondrial precursor, putative 0.0045 0.0234 0.0788
Loa Loa (eye worm) hypothetical protein 0.0024 0.0088 0.0295
Entamoeba histolytica hypothetical protein 0.0024 0.0088 0.0413
Loa Loa (eye worm) glutathione reductase 0.0131 0.0824 0.2778
Schistosoma mansoni hypothetical protein 0.0089 0.0535 0.0534
Trichomonas vaginalis chromobox protein, putative 0.0089 0.0535 0.1569
Trypanosoma cruzi ubiquitin-activating enzyme-like protein 0.0016 0.003 0.0058
Trypanosoma cruzi ubiquitin-activating enzyme, putative 0.0033 0.015 0.0336
Echinococcus granulosus histone acetyltransferase KAT2B 0.0151 0.0965 0.0965
Mycobacterium ulcerans hypothetical protein 0.0025 0.0092 0.0213
Echinococcus granulosus jumonji domain containing protein 0.0044 0.0222 0.0221
Trichomonas vaginalis chromodomain helicase DNA binding protein, putative 0.0031 0.0136 0.039
Trypanosoma brucei hypothetical protein, conserved 0.003 0.013 0.0289
Loa Loa (eye worm) ATP-dependent DNA helicase 0.0032 0.0142 0.0476
Brugia malayi nuclear hormone receptor 0.0022 0.0071 0.0238
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0069 0.0394 0.09
Schistosoma mansoni hypothetical protein 0.0066 0.0375 0.0375
Loa Loa (eye worm) hypothetical protein 0.0022 0.0071 0.0238
Toxoplasma gondii histone lysine acetyltransferase GCN5-A 0.0048 0.0255 0.2125
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0018 0.0045 0.0121
Loa Loa (eye worm) hypothetical protein 0.016 0.1028 0.3465
Schistosoma mansoni ubiquitin-activating enzyme E1b 0.0033 0.015 0.0149
Mycobacterium tuberculosis Probable NADH dehydrogenase Ndh 0.0299 0.1981 0.4803
Trichomonas vaginalis CAMK family protein kinase 0.0101 0.0621 0.1824
Schistosoma mansoni alpha-glucosidase 0.0151 0.096 0.096
Trypanosoma cruzi trypanothione reductase, putative 0.0045 0.0234 0.0531
Mycobacterium ulcerans phosphoglycerate kinase 0.0183 0.1182 0.2862
Trypanosoma cruzi cruzipain precursor, putative 0.0069 0.0394 0.09
Brugia malayi nuclear receptor NHR-88 0.0022 0.0071 0.0238
Trichomonas vaginalis chromobox protein, putative 0.0024 0.0088 0.0247
Echinococcus multilocularis dihydrolipoamide dehydrogenase 0.0045 0.0234 0.0234
Schistosoma mansoni steroid hormone receptor ad4bp 0.0022 0.0071 0.0071
Mycobacterium ulcerans citrate (pro-3S)-lyase subunit beta 0.0026 0.0103 0.0239
Loa Loa (eye worm) hypothetical protein 0.0151 0.0964 0.3251
Plasmodium falciparum thioredoxin reductase 0.0045 0.0234 0.1951
Brugia malayi Pyridine nucleotide-disulphide oxidoreductase family protein 0.0012 0.0004 0.0013
Mycobacterium ulcerans long-chain-fatty-acid--CoA ligase 0.0025 0.0092 0.0213
Schistosoma mansoni chromobox protein 0.0148 0.0939 0.0938
Loa Loa (eye worm) steroid hormone receptor 0.0022 0.0071 0.0238
Brugia malayi Bromodomain containing protein 0.0038 0.0181 0.0609
Echinococcus multilocularis cysteine protease 0.0018 0.0045 0.0045
Plasmodium vivax glutathione reductase, putative 0.0131 0.0824 0.696
Echinococcus multilocularis thioredoxin glutathione reductase 0.0132 0.0831 0.0831
Echinococcus multilocularis dna polymerase kappa 0.0126 0.0789 0.0789
Entamoeba histolytica deoxycytidyl transferase, putative 0.0097 0.0592 0.291
Trichomonas vaginalis Clan CA, family C1, cathepsin L or K-like cysteine peptidase 0.0018 0.0045 0.0121
Trypanosoma brucei dihydrolipoyl dehydrogenase 0.0045 0.0234 0.0531
Entamoeba histolytica myo-inositol monophosphatase, putative 0.004 0.0195 0.0943
Schistosoma mansoni histone-lysine n-methyltransferase setb1 0.0064 0.0362 0.0362
Loa Loa (eye worm) hypothetical protein 0.005 0.0268 0.0903
Loa Loa (eye worm) D-ets-4 DNA binding domain-containing protein 0.0078 0.0458 0.1543
Loa Loa (eye worm) ImpB/MucB/SamB family protein 0.0097 0.0592 0.1996
Onchocerca volvulus 0.0101 0.0619 0.183
Loa Loa (eye worm) DOMON domain-containing protein 0.0016 0.0029 0.0096
Loa Loa (eye worm) hypothetical protein 0.0018 0.0049 0.0163
Loa Loa (eye worm) jmjC domain-containing protein 0.0065 0.0367 0.1237
Schistosoma mansoni dihydrolipoamide dehydrogenase 0.0045 0.0234 0.0234
Trichomonas vaginalis disulfide oxidoreductase, putative 0.0012 0.0004 0.00000040069
Plasmodium falciparum JmjC domain-containing protein, putative 0.0027 0.0107 0.0873
Trichomonas vaginalis conserved hypothetical protein 0.0024 0.0088 0.0247
Mycobacterium ulcerans citrate (pro-3S)-lyase subunit beta 0.0026 0.0103 0.0239
Loa Loa (eye worm) hypothetical protein 0.0018 0.0049 0.0163
Onchocerca volvulus Bile acid receptor homolog 0.0022 0.0071 0.021
Loa Loa (eye worm) nuclear hormone receptor family member nhr-31 0.0022 0.0071 0.0238
Toxoplasma gondii ATP-dependent DNA helicase, RecQ family protein 0.0028 0.0112 0.0915
Plasmodium vivax acyl-CoA synthetase, putative 0.0018 0.0049 0.0377
Echinococcus granulosus Jumonji AT rich interactive domain 1B 0.0031 0.0133 0.0133
Echinococcus multilocularis Peptidase C19, ubiquitin carboxyl terminal hydrolase 2 0.0039 0.0187 0.0187
Echinococcus multilocularis FTZ F1 alpha 0.0022 0.0071 0.0071
Schistosoma mansoni ap endonuclease 0.002 0.0061 0.006
Mycobacterium tuberculosis NADPH-dependent mycothiol reductase Mtr 0.0131 0.0824 0.1992
Loa Loa (eye worm) hypothetical protein 0.0024 0.0088 0.0295
Trypanosoma cruzi dihydrolipoamide dehydrogenase, putative 0.0045 0.0234 0.0531
Entamoeba histolytica recQ family helicase, putative 0.0016 0.0029 0.0123
Echinococcus granulosus ubiquitin carboxyl terminal hydrolase 8 0.0039 0.0187 0.0187
Schistosoma mansoni alpha glucosidase 0.0039 0.0189 0.0189
Brugia malayi Cathepsin L-like precursor 0.0018 0.0045 0.0152
Trypanosoma cruzi 2,4-dihydroxyhept-2-ene-1,7-dioic acid aldolase, putative 0.0026 0.0103 0.0227
Echinococcus granulosus transcription factor Dp 1 0.0041 0.0204 0.0204
Echinococcus multilocularis ubiquitin specific protease 41 0.0039 0.0187 0.0187
Plasmodium vivax vivapain-2 0.0018 0.0045 0.0348
Echinococcus granulosus Chromo domain 0.0024 0.0088 0.0087
Toxoplasma gondii histone lysine demethylase JMJC1/KDM5D/JARID1D 0.0027 0.0107 0.0873
Trypanosoma cruzi PAS-domain containing phosphoglycerate kinase, putative 0.0067 0.0384 0.0878
Echinococcus multilocularis Nuclear hormone receptor family member nhr 41 0.0022 0.0071 0.0071
Echinococcus granulosus FTZ F1 alpha 0.0022 0.0071 0.0071
Mycobacterium ulcerans aldehyde dehydrogenase 0.0129 0.0808 0.1953
Brugia malayi mbt repeat family protein 0.0101 0.0618 0.2083
Echinococcus multilocularis dnaJ subfamily B 0.0439 0.2952 0.2951
Trichomonas vaginalis conserved hypothetical protein 0.0036 0.0169 0.0486
Mycobacterium ulcerans DNA polymerase IV 0.0126 0.0789 0.1908
Plasmodium vivax DNA repair protein REV1, putative 0.003 0.013 0.1063
Schistosoma mansoni DNA helicase recq5 0.0032 0.0142 0.0141
Onchocerca volvulus Cathepsin F homolog 0.0018 0.0045 0.0134
Brugia malayi PHD-finger family protein 0.0031 0.0137 0.0462
Trypanosoma cruzi ATP-dependent DEAD/H DNA helicase recQ, putative 0.0035 0.0163 0.0367
Echinococcus granulosus L aminoadipate semialdehyde 0.0176 0.1136 0.1135
Loa Loa (eye worm) DnaJ domain-containing protein 0.0066 0.0375 0.1264
Trichomonas vaginalis rotamase, putative 0.0035 0.0163 0.0469
Plasmodium vivax hypothetical protein, conserved 0.0024 0.0088 0.0709
Trypanosoma cruzi cysteine peptidase, putative 0.0069 0.0394 0.09
Trypanosoma cruzi dihydrolipoamide dehydrogenase, putative 0.0045 0.0234 0.0531
Echinococcus granulosus chromobox protein 2 0.0024 0.0088 0.0087
Loa Loa (eye worm) hypothetical protein 0.0041 0.0206 0.0692
Echinococcus multilocularis FTZ F1 nuclear receptor protein 0.0022 0.0071 0.0071
Plasmodium falciparum dihydrolipoyl dehydrogenase, apicoplast 0.0045 0.0234 0.1951
Echinococcus multilocularis hepatocyte nuclear factor 4 alpha 0.0022 0.0071 0.0071
Schistosoma mansoni jumonji domain containing protein 0.0027 0.0107 0.0107
Mycobacterium ulcerans extragenic suppressor protein SuhB 0.004 0.0195 0.0463
Leishmania major myo-inositol-1(or 4)-monophosphatase 1, putative 0.004 0.0195 0.044
Echinococcus multilocularis GA binding protein alpha chain 0.0078 0.0458 0.0457
Echinococcus granulosus sumo-activating enzyme subunit 2 0.0033 0.015 0.0149
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0069 0.0394 0.09
Toxoplasma gondii ATP-dependent DNA helicase, RecQ family protein 0.0032 0.0142 0.1165
Trypanosoma brucei glucosidase, putative 0.0039 0.0189 0.0427
Brugia malayi jmjC domain containing protein 0.0027 0.0107 0.036
Schistosoma mansoni inositol monophosphatase 0.004 0.0195 0.0195
Plasmodium vivax thioredoxin reductase, putative 0.0131 0.0824 0.696
Echinococcus multilocularis cathepsin l cysteine peptidase 0.0018 0.0045 0.0045
Echinococcus granulosus ATP dependent DNA helicase Q5 0.0032 0.0142 0.0141
Leishmania major 4-coumarate:coa ligase-like protein 0.0025 0.0092 0.0202
Echinococcus multilocularis ATP dependent DNA helicase Q5 0.0032 0.0142 0.0141
Trypanosoma cruzi myo-inositol-1(or 4)-monophosphatase 1, putative 0.004 0.0195 0.044
Entamoeba histolytica chromodomain-helicase-DNA-binding protein, putative 0.0024 0.0088 0.0413
Entamoeba histolytica chromodomain-helicase-DNA-binding protein, putative 0.0024 0.0088 0.0413
Trypanosoma brucei DNA polymerase kappa, putative 0.0126 0.0789 0.1814
Echinococcus multilocularis neutral alpha glucosidase AB 0.0039 0.0189 0.0189
Loa Loa (eye worm) inositol-1 0.004 0.0195 0.0656
Mycobacterium tuberculosis Probable reductase 0.0299 0.1981 0.4803
Schistosoma mansoni hypothetical protein 0.0177 0.1141 0.114
Echinococcus granulosus bromodomain adjacent to zinc finger domain 0.007 0.0402 0.0402
Trichomonas vaginalis chromodomain-helicase-DNA-binding protein, putative 0.0028 0.0114 0.0323
Echinococcus multilocularis thyroid hormone receptor alpha 0.0157 0.1004 0.1003
Plasmodium falciparum thioredoxin reductase 0.0131 0.0824 0.696
Echinococcus multilocularis chromobox protein 2 0.0024 0.0088 0.0087
Echinococcus granulosus Chromobox protein 3 0.0024 0.0088 0.0087
Schistosoma mansoni flap endonuclease-1 0.0025 0.0096 0.0095
Trichomonas vaginalis DNA helicase recq1, putative 0.0047 0.0246 0.0715
Schistosoma mansoni nuclear hormone receptor nor-1/nor-2 0.0022 0.0071 0.0071
Schistosoma mansoni retinoid-x-receptor (RXR) 0.0022 0.0071 0.0071
Trypanosoma brucei mitochondrial DNA polymerase beta 0.064 0.4332 1
Brugia malayi steroid hormone receptor 0.0022 0.0071 0.0238
Brugia malayi ecdysteroid receptor 0.0022 0.0071 0.0238
Mycobacterium tuberculosis Probable fatty-acid-CoA ligase FadD7 (fatty-acid-CoA synthetase) (fatty-acid-CoA synthase) 0.0017 0.0042 0.0091
Echinococcus multilocularis lysosomal alpha glucosidase 0.0175 0.1128 0.1128
Leishmania major phosphopantetheinyl transferase-like protein 0.005 0.0263 0.0597
Schistosoma mansoni histone-lysine n-methyltransferase setb1 0.0082 0.0488 0.0488
Trypanosoma cruzi ISWI complex protein 0.0016 0.0035 0.007
Loa Loa (eye worm) CHromoDomain protein family member 0.0028 0.0114 0.0384
Trypanosoma brucei ISWI complex protein 0.0016 0.0035 0.007
Trypanosoma brucei DNA damage repair protein, putative 0.003 0.013 0.0289
Wolbachia endosymbiont of Brugia malayi dihydrolipoamide dehydrogenase E3 component 0.0045 0.0234 0.0558
Mycobacterium tuberculosis Probable exodeoxyribonuclease III protein XthA (exonuclease III) (EXO III) (AP endonuclease VI) 0.002 0.0061 0.0137
Loa Loa (eye worm) bromodomain containing protein 0.0023 0.0078 0.0263
Trichomonas vaginalis DNA polymerase IV / kappa, putative 0.0126 0.0789 0.2321
Trichomonas vaginalis maltase-glucoamylase, putative 0.0014 0.0021 0.0049
Loa Loa (eye worm) heterochromatin protein 1 0.0148 0.0939 0.3165
Brugia malayi cathepsin L-like precursor 0.0012 0.0004 0.0013
Loa Loa (eye worm) hypothetical protein 0.0031 0.0137 0.0462
Leishmania major protein kinase, putative,polo-like protein kinase, putative 0.0101 0.0621 0.1425
Trichomonas vaginalis neutral alpha-glucosidase ab precursor, putative 0.0039 0.0189 0.0547
Mycobacterium ulcerans acyl-CoA synthetase 0.0025 0.0092 0.0213
Trichomonas vaginalis fructose-bisphosphate aldolase, putative 0.0305 0.2025 0.5975
Trypanosoma cruzi apurinic/apyrimidinic endonuclease, putative 0.002 0.0061 0.013
Echinococcus multilocularis transcription factor Dp 1 0.0041 0.0204 0.0204
Brugia malayi Nuclear hormone receptor family member nhr-31 0.0022 0.0071 0.0238
Schistosoma mansoni serine/threonine protein kinase 0.0101 0.0621 0.0621
Schistosoma mansoni histone-lysine n-methyltransferase suv9 0.0088 0.0528 0.0528
Echinococcus multilocularis muscleblind protein 1 0.016 0.1028 0.1028
Trichomonas vaginalis Clan CA, family C1, papain-like cysteine peptidase 0.0018 0.0045 0.0121
Toxoplasma gondii inositol(myo)-1(or 4)-monophosphatase 2, putative 0.004 0.0195 0.1618
Mycobacterium leprae possible inositol monophosphatase SubH (IMPase) (inositol-1-phosphatase) (I-1-Pase ). 0.0036 0.0166 0.0394
Plasmodium falciparum glutathione reductase 0.0131 0.0824 0.696
Echinococcus multilocularis aldehyde dehydrogenase, mitochondrial 0.0129 0.0808 0.0808
Echinococcus multilocularis histone lysine N methyltransferase SETMAR 0.0064 0.0362 0.0362
Echinococcus multilocularis MAM 0.0017 0.0037 0.0037
Schistosoma mansoni sex comb on midleg homolog 0.0101 0.0618 0.0618
Echinococcus granulosus Nuclear hormone receptor family member nhr 41 0.0022 0.0071 0.0071
Entamoeba histolytica ubiquitin carboxyl-terminal hydrolase domain containing protein 0.0039 0.0187 0.0906
Toxoplasma gondii ImpB/MucB/SamB family protein 0.0084 0.0502 0.4222
Onchocerca volvulus 0.0016 0.0029 0.0086
Brugia malayi Pre-SET motif family protein 0.0064 0.0362 0.1219
Trypanosoma cruzi apurinic/apyrimidinic endonuclease 0.002 0.0061 0.013
Onchocerca volvulus 0.0101 0.0618 0.1825
Plasmodium falciparum glutathione reductase 0.0045 0.0234 0.1951
Echinococcus granulosus expressed protein 0.0036 0.0169 0.0168
Brugia malayi Cathepsin L-like precursor 0.0018 0.0045 0.0152
Echinococcus granulosus pyridine nucleotide disulfide oxidoreductase 0.0012 0.0004 0.0004
Mycobacterium tuberculosis Probable aldehyde dehydrogenase 0.0129 0.0808 0.1953
Brugia malayi Cathepsin L-like precursor 0.0018 0.0045 0.0152
Entamoeba histolytica peptidyl-prolyl cis-trans isomerase, putative 0.0035 0.0163 0.0785
Trypanosoma cruzi dihydrolipoyl dehydrogenase, putative 0.0045 0.0234 0.0531
Onchocerca volvulus Alhambra homolog 0.0031 0.0137 0.0405
Toxoplasma gondii histone lysine acetyltransferase GCN5-B 0.0048 0.0255 0.2125
Trypanosoma cruzi peptidyl-prolyl cis-trans isomerase 0.0035 0.0163 0.0366
Trypanosoma cruzi DNA damage repair protein, putative 0.003 0.013 0.0289
Entamoeba histolytica fructose-1,6-bisphosphate aldolase, putative 0.0305 0.2025 1
Plasmodium vivax phosphoglycerate kinase, putative 0.0183 0.1182 1
Onchocerca volvulus 0.0088 0.0528 0.1561
Toxoplasma gondii histone lysine methyltransferase SET1 0.0067 0.0384 0.3226
Echinococcus granulosus PHD finger protein rhinoceros 0.0031 0.0137 0.0137
Plasmodium falciparum phosphoglycerate kinase 0.0183 0.1182 1
Trypanosoma cruzi hypothetical protein, conserved 0.0039 0.0189 0.0427
Mycobacterium ulcerans hypothetical protein 0.0026 0.0103 0.0239
Echinococcus granulosus histone lysine N methyltransferase MLL3 0.0012 0.0003 0.0003
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0018 0.0045 0.0121
Schistosoma mansoni hypothetical protein 0.0031 0.0137 0.0137
Brugia malayi glutathione reductase 0.0131 0.0824 0.2778
Mycobacterium tuberculosis Probable UDP-N-acetylglucosamine pyrophosphorylase GlmU 0.0609 0.4119 1
Chlamydia trachomatis holo [acyl-carrier protein] synthase 0.005 0.0263 0.2195
Trypanosoma cruzi ubiquitin-activating enzyme, putative 0.0028 0.0118 0.0262
Toxoplasma gondii hypothetical protein 0.0103 0.0633 0.5335
Schistosoma mansoni sex comb on midleg homolog 0.0101 0.0618 0.0618
Leishmania major cathepsin L-like protease 0.0069 0.0394 0.09
Entamoeba histolytica Flap nuclease, putative 0.0028 0.0114 0.0544
Brugia malayi Nuclear hormone receptor family member nhr-25 0.0022 0.0071 0.0238
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0069 0.0394 0.09
Plasmodium falciparum AP endonuclease (DNA-[apurinic or apyrimidinic site] lyase), putative 0.002 0.0061 0.0478
Schistosoma mansoni nuclear hormone receptor 0.0022 0.0071 0.0071
Echinococcus multilocularis cathepsin l cysteine peptidase 0.0018 0.0045 0.0045
Brugia malayi jmjC domain containing protein 0.0166 0.1064 0.3588
Brugia malayi Pre-SET motif family protein 0.0441 0.2966 1
Trichomonas vaginalis fructose-bisphosphate aldolase, putative 0.0305 0.2025 0.5975
Trypanosoma brucei inositol-1(or 4)-monophosphatase 1, putative 0.004 0.0195 0.044
Echinococcus multilocularis dna polymerase eta 0.0151 0.0964 0.0964
Loa Loa (eye worm) jmjC domain-containing protein 0.0027 0.0107 0.036
Brugia malayi ImpB/MucB/SamB family protein 0.0151 0.0964 0.3251
Trichomonas vaginalis bromodomain-containing protein, putative 0.0048 0.0255 0.074
Schistosoma mansoni jumonji/arid domain-containing protein 0.0105 0.0645 0.0644
Loa Loa (eye worm) jmjC domain-containing protein 0.0027 0.0107 0.036
Echinococcus granulosus terminal deoxycytidyl transferase rev1 0.0097 0.0592 0.0592
Loa Loa (eye worm) hypothetical protein 0.0018 0.0049 0.0163
Leishmania major DNA polymerase kappa, putative 0.0104 0.0641 0.1471
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0018 0.0045 0.0121
Toxoplasma gondii thioredoxin reductase 0.0131 0.0824 0.696
Echinococcus granulosus geminin 0.0177 0.1141 0.114
Schistosoma mansoni zinc finger protein 0.0027 0.0105 0.0104
Mycobacterium tuberculosis Probable nitrite reductase [NAD(P)H] large subunit [FAD flavoprotein] NirB 0.0299 0.1981 0.4803
Trypanosoma cruzi phosphoglycerate kinase, putative 0.0183 0.1182 0.2721
Loa Loa (eye worm) hypothetical protein 0.0176 0.1136 0.3828
Onchocerca volvulus Rap guanine nucleotide exchange factor 1 homolog 0.0188 0.1221 0.3605
Schistosoma mansoni disulfide oxidoreductase 0.0012 0.0004 0.0004
Leishmania major 2,4-dihydroxyhept-2-ene-1,7-dioic acid aldolase, putative 0.0026 0.0103 0.0227
Schistosoma mansoni zinc finger protein 0.0016 0.0035 0.0034
Brugia malayi ImpB/MucB/SamB family protein 0.0097 0.0592 0.1996
Loa Loa (eye worm) nuclear Hormone Receptor family member 0.0022 0.0071 0.0238
Loa Loa (eye worm) hypothetical protein 0.0083 0.0492 0.1657
Trypanosoma brucei phosphoglycerate kinase 0.0183 0.1182 0.2721
Trypanosoma brucei phosphoglycerate kinase, putative 0.0067 0.0384 0.0878
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0018 0.0045 0.0121
Schistosoma mansoni bcl-2 homologous antagonist/killer (bak) 0.0089 0.0535 0.0534
Schistosoma mansoni hypothetical protein 0.0024 0.0088 0.0087
Loa Loa (eye worm) Pin1-type peptidyl-prolyl cis-trans isomerase 0.0036 0.0169 0.0568
Echinococcus multilocularis terminal deoxycytidyl transferase rev1 0.0097 0.0592 0.0592
Trypanosoma cruzi phosphoglycerate kinase, putative 0.0067 0.0384 0.0878
Echinococcus multilocularis cpg binding protein 0.0035 0.016 0.016
Toxoplasma gondii 4'-phosphopantetheinyl transferase domain-containing protein 0.005 0.0263 0.2195
Loa Loa (eye worm) helicase 0.0024 0.0088 0.0295
Plasmodium falciparum cysteine proteinase falcipain 2a 0.0018 0.0045 0.0348
Leishmania major DNA polymerase kappa, putative,DNA polymerase IV, putative 0.0104 0.0641 0.1471
Echinococcus granulosus methyl CpG binding domain protein 2 0.0018 0.0048 0.0047
Loa Loa (eye worm) hypothetical protein 0.0024 0.0088 0.0295
Echinococcus granulosus cathepsin l cysteine peptidase 0.0018 0.0045 0.0045
Trichomonas vaginalis glutamate synthase, putative 0.0012 0.0004 0.00000040069
Entamoeba histolytica fructose-1,6-bisphosphate aldolase, putative 0.0305 0.2025 1
Schistosoma mansoni ubiquitin-specific peptidase 8 (C19 family) 0.0039 0.0187 0.0187
Echinococcus granulosus phd:f box containing protein 0.0027 0.0107 0.0107
Toxoplasma gondii PHD-finger domain-containing protein 0.0031 0.0137 0.1129
Brugia malayi CHD4 protein 0.0028 0.0114 0.0384
Echinococcus multilocularis chromobox protein 1 0.0148 0.0939 0.0938
Onchocerca volvulus Serine\/threonine kinase homolog 0.0101 0.0621 0.1835
Brugia malayi AMP-binding enzyme family protein 0.0025 0.0092 0.0309
Echinococcus granulosus chromobox protein 1 0.0148 0.0939 0.0938
Trichomonas vaginalis CAMK family protein kinase 0.0101 0.0621 0.1824
Plasmodium vivax ubiquitin activating enzyme, putative 0.005 0.0268 0.2241
Echinococcus granulosus JmjC domain containing protein 4 0.0027 0.0107 0.0107
Loa Loa (eye worm) hypothetical protein 0.0022 0.0071 0.0238
Wolbachia endosymbiont of Brugia malayi exonuclease III 0.002 0.0061 0.0137
Leishmania major flap endonuclease-1 (FEN-1), putative 0.0028 0.0114 0.0254
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0069 0.0394 0.09
Giardia lamblia Sgs1 DNA helicase, putative 0.0032 0.0142 0.0679
Schistosoma mansoni microtubule-associated protein tau 0.1461 1 1
Brugia malayi Cathepsin L-like precursor 0.0018 0.0045 0.0152
Mycobacterium tuberculosis Possible DNA-damage-inducible protein P DinP (DNA polymerase V) (pol IV 2) (DNA nucleotidyltransferase (DNA-directed)) 0.0104 0.0641 0.1548
Trichomonas vaginalis ap endonuclease, putative 0.002 0.0061 0.0166
Entamoeba histolytica glutamate synthase beta subunit, putative 0.0012 0.0004 0.00000067057
Trypanosoma brucei DNA polymerase kappa, putative 0.0059 0.0327 0.0744
Loa Loa (eye worm) hypothetical protein 0.0032 0.0142 0.0476
Echinococcus multilocularis citrate lyase subunit beta protein 0.0026 0.0103 0.0102
Echinococcus multilocularis chromodomain helicase DNA binding protein 4 0.0028 0.0114 0.0114
Brugia malayi Papain family cysteine protease containing protein 0.0018 0.0045 0.0152
Trichomonas vaginalis conserved hypothetical protein 0.0024 0.0088 0.0247
Mycobacterium ulcerans 4'-phosphopantetheinyl transferase 0.005 0.0263 0.0628
Echinococcus multilocularis suppression of tumorigenicity 18 protein 0.0115 0.0714 0.0714
Leishmania major cathepsin L-like protease 0.0018 0.0045 0.0095
Entamoeba histolytica acyl-CoA synthetase, putative 0.0025 0.0092 0.0434
Trypanosoma brucei ATP-dependent DEAD/H DNA helicase recQ, putative 0.0035 0.0163 0.0367
Echinococcus granulosus retinoic acid receptor rxr beta a 0.0022 0.0071 0.0071
Trichomonas vaginalis phosphoglycerate kinase, putative 0.0183 0.1182 0.3483
Mycobacterium ulcerans hypothetical protein 0.0026 0.0103 0.0239
Entamoeba histolytica hypothetical protein 0.005 0.0263 0.1279
Toxoplasma gondii histone lysine methyltransferase SET/SUV39 0.0064 0.0362 0.3036
Echinococcus granulosus ecdysone induced protein 78C 0.0022 0.0071 0.0071
Brugia malayi jmjC domain containing protein 0.0027 0.0107 0.036
Echinococcus granulosus dihydropyrimidine dehydrogenase NADP 0.0012 0.0004 0.0004
Toxoplasma gondii hypothetical protein 0.005 0.0268 0.2241
Schistosoma mansoni histone-lysine n-methyltransferase setb1 0.0082 0.0488 0.0488
Brugia malayi ThiF family protein 0.005 0.0268 0.0903
Trypanosoma brucei glycosyl hydrolase-like protein 0.0014 0.0021 0.0039
Trypanosoma brucei DNA polymerase IV, putative 0.0126 0.0789 0.1814
Schistosoma mansoni kinase 0.0052 0.0277 0.0277
Brugia malayi glutamate synthase 0.0012 0.0004 0.0013
Loa Loa (eye worm) ctsf protein 0.0018 0.0045 0.0152
Brugia malayi M-phase phosphoprotein, mpp8 0.0024 0.0088 0.0295
Schistosoma mansoni phosphoglycerate kinase 0.0183 0.1182 0.1182
Onchocerca volvulus 0.0502 0.3386 1
Trichomonas vaginalis glutamate synthase, putative 0.0012 0.0004 0.00000040069
Schistosoma mansoni hypothetical protein 0.0016 0.0035 0.0034
Echinococcus multilocularis gcn5proteinral control of amino acid synthesis 0.0158 0.1013 0.1012
Trichomonas vaginalis conserved hypothetical protein 0.0024 0.0088 0.0247
Plasmodium falciparum heterochromatin protein 1 0.0024 0.0088 0.0709
Entamoeba histolytica thioredoxin reductase, putative 0.0012 0.0004 0.00000067057
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0018 0.0045 0.0121
Trichomonas vaginalis Clan CA, family C1, papain-like cysteine peptidase 0.0018 0.0045 0.0121
Schistosoma mansoni cathepsin F (C01 family) 0.0018 0.0045 0.0045
Mycobacterium ulcerans DNA polymerase IV 0.0126 0.0789 0.1908
Trichomonas vaginalis alpha-glucosidase, putative 0.0039 0.0189 0.0547
Loa Loa (eye worm) hypothetical protein 0.0016 0.0034 0.0112
Onchocerca volvulus 0.0017 0.0037 0.011
Trypanosoma cruzi ubiquitin carboxyl-terminal hydrolase, putative 0.0039 0.0187 0.0423
Brugia malayi Steroid receptor seven-up type 2 0.0022 0.0071 0.0238
Mycobacterium tuberculosis Probable membrane NADH dehydrogenase NdhA 0.0299 0.1981 0.4803
Schistosoma mansoni chromobox protein 0.0148 0.0939 0.0938
Loa Loa (eye worm) tyrosyl-DNA phosphodiesterase 0.0071 0.041 0.1382
Trypanosoma brucei DNA polymerase kappa, putative 0.0059 0.0327 0.0744
Echinococcus granulosus Transcription factor JmjC domain containing protein 0.0166 0.1064 0.1064
Plasmodium vivax histone acetyltransferase GCN5, putative 0.0048 0.0255 0.2125
Trypanosoma cruzi phosphoglycerate kinase, putative 0.0183 0.1182 0.2721
Loa Loa (eye worm) hypothetical protein 0.0048 0.0249 0.084
Trypanosoma brucei unspecified product 0.0119 0.074 0.1701
Trypanosoma brucei DNA polymerase IV, putative 0.0119 0.074 0.1701
Trichomonas vaginalis Clan CA, family C1, cathepsin L or K-like cysteine peptidase 0.0018 0.0045 0.0121
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0069 0.0394 0.09
Trichomonas vaginalis sucrase-isomaltase, putative 0.0039 0.0189 0.0547
Brugia malayi Glycosyl hydrolases family 31 protein 0.0175 0.1128 0.3804
Echinococcus granulosus SUMO activating enzyme subunit 1 0.005 0.0268 0.0268
Trichomonas vaginalis alpha-glucosidase, putative 0.0039 0.0189 0.0547
Loa Loa (eye worm) PLK/PLK1 protein kinase 0.0101 0.0621 0.2093
Chlamydia trachomatis acylglycerophosphoethanolamine acyltransferase 0.0018 0.0049 0.0377
Loa Loa (eye worm) hypothetical protein 0.0022 0.0071 0.0238
Leishmania major phosphoglycerate kinase B, cytosolic 0.0183 0.1182 0.2721
Mycobacterium leprae PROBABLE FATTY-ACID-CoA LIGASE FADD2 (FATTY-ACID-CoA SYNTHETASE) (FATTY-ACID-CoA SYNTHASE) 0.0025 0.0092 0.0213
Trichomonas vaginalis chromodomain helicase DNA binding protein, putative 0.0024 0.0088 0.0247
Trichomonas vaginalis fructose-bisphosphate aldolase, putative 0.0305 0.2025 0.5975
Echinococcus multilocularis phosphoglycerate kinase 1 0.0183 0.1182 0.1182
Plasmodium falciparum conserved Plasmodium membrane protein, unknown function 0.0012 0.0005 0.0004
Toxoplasma gondii NADPH-glutathione reductase 0.0045 0.0234 0.1951
Leishmania major DNA polymerase kappa, putative 0.003 0.013 0.0289
Trichomonas vaginalis CAMK family protein kinase 0.005 0.0268 0.0779
Brugia malayi Nuclear hormone receptor family member nhr-1 0.0022 0.0071 0.0238
Trichomonas vaginalis conserved hypothetical protein 0.0024 0.0088 0.0247
Loa Loa (eye worm) glutaminase 2 0.0294 0.1946 0.6563
Brugia malayi Nuclear hormone receptor family member nhr-49 0.0022 0.0071 0.0238
Trypanosoma cruzi hypothetical protein, conserved 0.003 0.013 0.0289
Trichomonas vaginalis chromodomain helicase DNA binding protein, putative 0.0031 0.0136 0.039
Loa Loa (eye worm) hypothetical protein 0.0025 0.0092 0.0309
Loa Loa (eye worm) CXXC zinc finger family protein 0.0031 0.0134 0.0451
Trypanosoma cruzi myo-inositol-1(or 4)-monophosphatase 1, putative 0.004 0.0195 0.044
Chlamydia trachomatis dihydrolipoyl dehydrogenase 0.0045 0.0234 0.1951
Entamoeba histolytica cysteine proteinase, putative 0.0018 0.0045 0.0203
Trichomonas vaginalis CAMK family protein kinase 0.0101 0.0621 0.1824
Mycobacterium ulcerans fatty-acid-CoA ligase 0.0018 0.0049 0.0108
Trypanosoma cruzi trypanothione reductase, putative 0.0131 0.0824 0.1894
Brugia malayi Nuclear hormone receptor family member nhr-40 0.0022 0.0071 0.0238
Schistosoma mansoni methyl-cpg binding protein mbd 0.0018 0.0048 0.0047
Schistosoma mansoni coup transcription factor 0.0022 0.0071 0.0071
Trichomonas vaginalis hypothetical protein 0.0024 0.0088 0.0247
Treponema pallidum fructose-bisphosphate aldolase 0.0305 0.2025 1
Echinococcus granulosus citrate lyase subunit beta protein 0.0026 0.0103 0.0102
Mycobacterium ulcerans flavoprotein disulfide reductase 0.0045 0.0234 0.0558
Onchocerca volvulus 0.0017 0.0037 0.011
Echinococcus granulosus polycomb protein SCMH1 0.0101 0.0618 0.0618
Mycobacterium tuberculosis Probable fatty-acid-CoA ligase FadD35 (fatty-acid-CoA synthetase) (fatty-acid-CoA synthase) 0.0017 0.0042 0.0091
Trichomonas vaginalis CAMK family protein kinase 0.005 0.0268 0.0779
Loa Loa (eye worm) exodeoxyribonuclease III family protein 0.002 0.0061 0.0203
Echinococcus multilocularis SAM and MBT domain containing protein 0.0101 0.0618 0.0618
Trichomonas vaginalis Heterochromatin protein, putative 0.0024 0.0088 0.0247
Leishmania major dihydrolipoamide dehydrogenase, putative 0.0045 0.0234 0.0531
Plasmodium falciparum histone acetyltransferase GCN5 0.0042 0.0211 0.1753
Trypanosoma brucei DNA polymerase beta thumb, putative 0.009 0.0542 0.1241
Trichomonas vaginalis fructose-bisphosphate aldolase, putative 0.0305 0.2025 0.5975
Schistosoma mansoni cpg binding protein 0.0035 0.016 0.016
Loa Loa (eye worm) hypothetical protein 0.0039 0.0187 0.0631
Leishmania major trypanothione reductase 0.0131 0.0824 0.1894
Trichomonas vaginalis conserved hypothetical protein 0.0024 0.0088 0.0247
Treponema pallidum NADH oxidase 0.0045 0.0234 0.1137
Leishmania major ubiquitin hydrolase, putative,cysteine peptidase, Clan CA, family C19, putative 0.0039 0.0187 0.0423
Leishmania major tyrosyl-DNA phosphodiesterase 1 0.0071 0.041 0.0938
Schistosoma mansoni photoreceptor-specific nuclear receptor related 0.0022 0.0071 0.0071
Echinococcus multilocularis lysine specific demethylase 5A 0.0101 0.0618 0.0618
Brugia malayi Heterochromatin protein 1 0.0148 0.0939 0.3165
Schistosoma mansoni hypothetical protein 0.0017 0.0037 0.0037
Trypanosoma cruzi tyrosyl-DNA Phosphodiesterase (Tdp1), putative 0.0071 0.041 0.0938
Echinococcus multilocularis NADPH:adrenodoxin oxidoreductase 0.0012 0.0004 0.0004
Echinococcus multilocularis dihydropyrimidine dehydrogenase (NADP+) 0.0012 0.0004 0.0004
Trypanosoma cruzi mitochondrial DNA polymerase beta-PAK, putative 0.011 0.0677 0.1555
Trypanosoma brucei DNA polymerase eta, putative 0.0151 0.0964 0.2218
Loa Loa (eye worm) pre-SET domain-containing protein family protein 0.0441 0.2966 1
Entamoeba histolytica hypothetical protein 0.0024 0.0088 0.0413
Trypanosoma cruzi dihydrolipoamide dehydrogenase, putative 0.0045 0.0234 0.0531
Mycobacterium leprae DIHYDROLIPOAMIDE DEHYDROGENASE LPD (LIPOAMIDE REDUCTASE (NADH)) (LIPOYL DEHYDROGENASE) (DIHYDROLIPOYL DEHYDROGENASE) (DIAPHORASE 0.0332 0.221 0.5361
Trichomonas vaginalis Clan CA, family C1, papain-like cysteine peptidase 0.0018 0.0045 0.0121
Mycobacterium ulcerans phosphopantetheinyl transferase, PptII 0.005 0.0263 0.0628
Wolbachia endosymbiont of Brugia malayi N-acetylglucosamine-1-phosphate uridyltransferase 0.0609 0.4119 1
Leishmania major acetoin dehydrogenase e3 component-like protein 0.0045 0.0234 0.0531
Entamoeba histolytica glycosyl hydrolase, family 31 protein 0.0039 0.0189 0.0915
Onchocerca volvulus Heterochromatin protein 1 homolog 0.0089 0.0535 0.158
Echinococcus multilocularis cathepsin L cysteine protease 0.0018 0.0045 0.0045
Trichomonas vaginalis fructose-bisphosphate aldolase, putative 0.0305 0.2025 0.5975
Toxoplasma gondii eukaryotic initiation factor-2B, gamma subunit, putative 0.0112 0.0691 0.583
Echinococcus multilocularis geminin 0.0177 0.1141 0.114
Schistosoma mansoni aldehyde dehydrogenase 0.0129 0.0808 0.0808
Trypanosoma cruzi hypothetical protein, conserved 0.0229 0.1497 0.345
Mycobacterium tuberculosis Probable dehydrogenase 0.0299 0.1981 0.4803
Giardia lamblia Phosphoglycerate kinase 0.0183 0.1182 0.583
Brugia malayi Cathepsin L-like precursor 0.0012 0.0004 0.0013
Trypanosoma brucei trypanothione reductase 0.0131 0.0824 0.1894
Leishmania major cathepsin L-like protease 0.0018 0.0045 0.0095
Loa Loa (eye worm) hypothetical protein 0.0022 0.0071 0.0238
Toxoplasma gondii exonuclease III APE 0.002 0.0061 0.0478
Mycobacterium ulcerans molybdopterin-guanine dinucleotide biosynthesis protein A 0.0112 0.0691 0.1669
Brugia malayi N-terminal motif family protein 0.0188 0.1221 0.4115
Echinococcus granulosus neutral alpha glucosidase AB 0.0039 0.0189 0.0189
Echinococcus granulosus serine:threonine protein kinase PLK1 0.0101 0.0621 0.0621
Onchocerca volvulus Heterochromatin protein 1 homolog 0.0083 0.0492 0.1452
Entamoeba histolytica tyrosyl-DNA phosphodiesterase, putative 0.0071 0.041 0.201
Trypanosoma cruzi DNA damage repair protein, putative 0.003 0.013 0.0289
Leishmania major phosphoglycerate kinase C, glycosomal 0.0183 0.1182 0.2721
Onchocerca volvulus 0.0012 0.0004 0.0013
Trichomonas vaginalis chromodomain helicase DNA binding protein, putative 0.0031 0.0136 0.039
Brugia malayi Protein cec-1. 0.0024 0.0088 0.0295
Mycobacterium leprae Probable fructose bisphosphate aldolase Fba 0.0149 0.0949 0.2295
Schistosoma mansoni ubiquitin-specific peptidase 2 (C19 family) 0.0039 0.0187 0.0187
Schistosoma mansoni phd/f-box containing protein 0.0027 0.0107 0.0107
Brugia malayi F/Y-rich N-terminus family protein 0.0024 0.0087 0.0292
Trichomonas vaginalis alpha-glucosidase, putative 0.0039 0.0189 0.0547
Trichomonas vaginalis apoptosis inducing factor, putative 0.0012 0.0004 0.00000040069
Entamoeba histolytica phosphoglycerate kinase, putative 0.0183 0.1182 0.583
Loa Loa (eye worm) hypothetical protein 0.0014 0.0021 0.007
Plasmodium falciparum flap endonuclease 1 0.0028 0.0114 0.0933
Leishmania major cathepsin L-like protease 0.0069 0.0394 0.09
Leishmania major ubiquitin-activating enzyme-like protein 0.0033 0.015 0.0336
Entamoeba histolytica recQ family helicase, putative 0.0035 0.0163 0.0786
Loa Loa (eye worm) TK/ALK protein kinase 0.0017 0.0037 0.0124
Echinococcus multilocularis lysosomal alpha glucosidase 0.0175 0.1128 0.1128
Wolbachia endosymbiont of Brugia malayi dihydrolipoamide dehydrogenase E3 component 0.0045 0.0234 0.0558
Trypanosoma cruzi dihydrolipoamide dehydrogenase, putative 0.0045 0.0234 0.0531
Toxoplasma gondii ATP-dependent DNA helicase, RecQ family protein 0.0016 0.0034 0.0248
Plasmodium vivax vivapain-2 0.0018 0.0045 0.0348
Onchocerca volvulus 0.0018 0.0045 0.0134
Loa Loa (eye worm) RecQ helicase 0.0047 0.0246 0.0828
Trypanosoma cruzi DNA polymerase kappa, putative 0.0126 0.0789 0.1814
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0018 0.0045 0.0121
Mycobacterium tuberculosis Conserved hypothetical protein 0.0112 0.0691 0.1669
Plasmodium vivax ADP-dependent DNA helicase RecQ, putative 0.0028 0.0116 0.0951
Echinococcus multilocularis histone lysine methyltransferase setb histone lysine methyltransferase eggless 0.0082 0.0488 0.0488
Loa Loa (eye worm) thioredoxin reductase 0.0131 0.0824 0.2778
Brugia malayi hypothetical protein 0.0017 0.0037 0.0124
Toxoplasma gondii peptidylprolyl isomerase 0.0035 0.0163 0.1346
Mycobacterium ulcerans hypothetical protein 0.003 0.013 0.0304
Trichomonas vaginalis chromodomain-helicase-DNA-binding protein, putative 0.0024 0.0088 0.0247
Echinococcus granulosus phosphoglycerate kinase 1 0.0183 0.1182 0.1182
Brugia malayi NADPH:adrenodoxin oxidoreductase, mitochondrial precursor 0.0012 0.0004 0.0013
Trichomonas vaginalis chromobox protein, putative 0.0089 0.0535 0.1569
Trypanosoma cruzi ATP-dependent DEAD/H DNA helicase recQ, putative 0.0016 0.0034 0.0068
Mycobacterium ulcerans fructose-bisphosphate aldolase 0.0149 0.0949 0.2295
Echinococcus granulosus peregrin 0.0038 0.0181 0.0181
Trypanosoma brucei hypothetical protein, conserved 0.0229 0.1497 0.345
Schistosoma mansoni cpg binding protein 0.0035 0.016 0.016
Trichomonas vaginalis alpha-glucosidase, putative 0.0039 0.0189 0.0547
Mycobacterium ulcerans hypothetical protein 0.0337 0.2245 0.5445
Trichomonas vaginalis CAMK family protein kinase 0.0101 0.0621 0.1824
Brugia malayi serine/threonine-protein kinase plk-2 0.0101 0.0621 0.2093
Loa Loa (eye worm) hypothetical protein 0.0018 0.0045 0.0152
Schistosoma mansoni bromodomain-containing nuclear protein 1 brd1 0.0031 0.0137 0.0137
Echinococcus granulosus cathepsin l1 0.0012 0.0004 0.0004
Trypanosoma brucei DNA damage repair protein, putative 0.003 0.013 0.0289
Mycobacterium ulcerans aldehyde dehydrogenase 0.0129 0.0808 0.1953
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0018 0.0045 0.0121
Schistosoma mansoni chromodomain helicase DNA binding protein 0.0024 0.0088 0.0087
Echinococcus multilocularis DNA (apurinic or apyrimidinic site) lyase 0.002 0.0061 0.006
Brugia malayi Muscle positioning protein 4 0.0016 0.0029 0.0096
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0018 0.0045 0.0121
Entamoeba histolytica ubiquitin-activating enzyme, putative 0.0016 0.003 0.0125
Echinococcus multilocularis EGFP:Bcl2 fusion protein 0.0089 0.0535 0.0534
Trypanosoma brucei DNA polymerase kappa, putative 0.0126 0.0789 0.1814
Mycobacterium tuberculosis Probable fatty-acid-CoA ligase FadD2 (fatty-acid-CoA synthetase) (fatty-acid-CoA synthase) 0.0025 0.0092 0.0213
Brugia malayi C2-HC type zinc finger protein C.e-MyT1 0.0115 0.0714 0.2408
Toxoplasma gondii 4'-phosphopantetheinyl transferase superfamily protein 0.005 0.0263 0.2195
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0018 0.0045 0.0121
Echinococcus multilocularis histone lysine N methyltransferase MLL3 0.0012 0.0003 0.0003
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0069 0.0394 0.09
Onchocerca volvulus 0.0018 0.0045 0.0134
Trichomonas vaginalis inositol monophosphatase, putative 0.004 0.0195 0.0564
Trichomonas vaginalis Clan CA, family C1, papain-like cysteine peptidase 0.0018 0.0045 0.0121
Leishmania major 4-coumarate:coa ligase-like protein 0.0025 0.0092 0.0202
Entamoeba histolytica recQ family DNA helicase 0.0016 0.0034 0.0145
Onchocerca volvulus 0.0018 0.0045 0.0134
Entamoeba histolytica glycosyl hydrolase, family 31 protein 0.0014 0.0021 0.0083
Trichomonas vaginalis disulfide oxidoreductase, putative 0.0012 0.0004 0.00000040069
Treponema pallidum licC protein (licC) 0.0112 0.0691 0.3399
Schistosoma mansoni hypothetical protein 0.0089 0.0535 0.0534
Trichomonas vaginalis neutral alpha-glucosidase ab precursor, putative 0.0014 0.0021 0.0049
Schistosoma mansoni myelin transcription factor 1 myt1 0.0115 0.0714 0.0714
Loa Loa (eye worm) Papain cysteine protease/cathepsin propeptide inhibitor-containing protein 0.0018 0.0045 0.0152
Schistosoma mansoni hypothetical protein 0.0177 0.1141 0.114
Toxoplasma gondii PHD-finger domain-containing protein 0.0031 0.0137 0.1129
Loa Loa (eye worm) glutaminase 0.0294 0.1946 0.6563
Trichomonas vaginalis CAMK family protein kinase 0.0101 0.0621 0.1824
Trichomonas vaginalis Clan CA, family C1, papain-like cysteine peptidase 0.0018 0.0045 0.0121
Trichomonas vaginalis conserved hypothetical protein 0.0039 0.0187 0.0542
Brugia malayi Protein kinase domain containing protein 0.0017 0.0037 0.0124
Trichomonas vaginalis alpha-glucosidase, putative 0.0014 0.0021 0.0049
Trichomonas vaginalis conserved hypothetical protein 0.0028 0.0114 0.0323
Trichomonas vaginalis Clan CA, family C1, papain-like cysteine peptidase 0.0018 0.0045 0.0121
Giardia lamblia Fructose-bisphosphate aldolase 0.0305 0.2025 1
Loa Loa (eye worm) nuclear hormone receptor family member nhr-49 0.0022 0.0071 0.0238
Trypanosoma brucei DNA polymerase kappa, putative 0.0126 0.0789 0.1814
Brugia malayi Ets-domain containing protein 0.0078 0.0458 0.1543
Loa Loa (eye worm) hypothetical protein 0.0017 0.0037 0.0124
Trichomonas vaginalis glutathione reductase, putative 0.0045 0.0234 0.068
Trichomonas vaginalis alpha-glucosidase, putative 0.0014 0.0021 0.0049
Loa Loa (eye worm) papain family cysteine protease containing protein 0.0018 0.0045 0.0152
Schistosoma mansoni chromobox protein-related (chromobox 1) (heterochromatin 1) 0.0024 0.0088 0.0087
Brugia malayi DnaJ domain containing protein 0.0066 0.0375 0.1264
Echinococcus granulosus lysine specific demethylase 5A 0.0105 0.0645 0.0644
Loa Loa (eye worm) hypothetical protein 0.0012 0.0004 0.0013
Brugia malayi Ligand-binding domain of nuclear hormone receptor family protein 0.0022 0.0071 0.0238
Brugia malayi mbt repeat family protein 0.0101 0.0618 0.2083
Onchocerca volvulus 0.0176 0.1136 0.3354
Schistosoma mansoni ets-related 0.0236 0.155 0.155
Treponema pallidum phosphoglycerate kinase 0.0183 0.1182 0.583
Loa Loa (eye worm) MBCTL1 0.0115 0.0714 0.2408
Schistosoma mansoni bromodomain containing protein 0.0074 0.0429 0.0428
Trichomonas vaginalis cat eye syndrome critical region protein 2, cscr2, putative 0.0048 0.0255 0.074
Schistosoma mansoni mixed-lineage leukemia protein mll 0.002 0.0061 0.006
Giardia lamblia PHD finger protein 15 0.0031 0.0137 0.0658
Brugia malayi SEA domain containing protein 0.0016 0.0029 0.0096
Toxoplasma gondii cathepsin CPL 0.0018 0.0045 0.0348
Trypanosoma cruzi hypothetical protein, conserved 0.0039 0.0189 0.0427
Trichomonas vaginalis neutral alpha-glucosidase ab precursor, putative 0.0014 0.0021 0.0049
Trypanosoma cruzi major cysteine proteinase, putative 0.0054 0.0293 0.0666
Brugia malayi Inositol-1 0.004 0.0195 0.0656
Schistosoma mansoni glutamate synthase 0.0012 0.0004 0.0004
Echinococcus granulosus histone acetyltransferase KAT2B 0.0048 0.0255 0.0254
Echinococcus multilocularis chromobox protein 1 0.0148 0.0939 0.0938
Trypanosoma brucei JmjC domain, hydroxylase, putative 0.0027 0.0107 0.0238
Leishmania major glycosyl hydrolase-like protein 0.0014 0.0021 0.0039
Trypanosoma brucei DNA polymerase kappa, putative 0.0126 0.0789 0.1814
Onchocerca volvulus 0.0024 0.0088 0.0259
Brugia malayi Nuclear hormone receptor family member nhr-19 0.0022 0.0071 0.0238
Echinococcus multilocularis nuclear receptor 2DBD gamma 0.0022 0.0071 0.0071
Echinococcus granulosus FTZ F1 nuclear receptor protein 0.0022 0.0071 0.0071
Trypanosoma brucei hypothetical protein, conserved 0.005 0.0263 0.0597
Loa Loa (eye worm) hypothetical protein 0.0022 0.0071 0.0238
Trichomonas vaginalis phosphoglycerate kinase, putative 0.0183 0.1182 0.3483
Toxoplasma gondii phosphoglycerate kinase PGKII 0.0183 0.1182 1
Schistosoma mansoni DNA helicase recq1 0.0032 0.0142 0.0141
Echinococcus multilocularis COUP TF:Svp nuclear hormone receptor 0.0022 0.0071 0.0071
Echinococcus multilocularis chromodomain helicase DNA binding protein 1 0.0024 0.0088 0.0087

Activities

No activities found for this compound.

Phenotypes

Whole-cell/tissue/organism interactions

We have no records of whole-cell/tissue assays done with this compound What does this mean?

Many chemical entities in TDR Targets come from high-throughput screenings with whole cells or tissue samples, and not all assayed compounds have been tested against a single a single target protein, probably because they get ruled out during screening process. Even if these compounds may have not been of interest in the original screening, they may come as interesting leads for other screening assays. Furthermore, we may be able to propose drug-target associations using chemical similarities and network patterns.

Annotated phenotypes:

We have no manually annotated phenotypes for this drug. What does this mean? / Care to help?
In TDR Targets, information about phenotypes that are caused by drugs, or by genetic manipulation of cells (e.g. gene knockouts or knockdowns) is manually curated from the literature. These descriptions help to describe the potential of the target for drug development. If no information is available for this gene or if the information is incomplete, this may mean that i) the papers containing this information either appeared after the curation effort for this organism was carried out or they were inadvertently missed by curators; or that ii) the curation effort for this organism has not yet started.
 
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External resources for this compound

Bibliographic References

No literature references available for this target.

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