Detailed information for compound 100708

Basic information

Technical information
  • TDR Targets ID: 100708
  • Name: 4-[2-(benzylamino)ethoxy]-1,3-dihydroindol-2- one
  • MW: 282.337 | Formula: C17H18N2O2
  • H donors: 2 H acceptors: 1 LogP: 1.81 Rotable bonds: 6
    Rule of 5 violations (Lipinski): 1
  • SMILES: O=C1Nc2c(C1)c(OCCNCc1ccccc1)ccc2
  • InChi: 1S/C17H18N2O2/c20-17-11-14-15(19-17)7-4-8-16(14)21-10-9-18-12-13-5-2-1-3-6-13/h1-8,18H,9-12H2,(H,19,20)
  • InChiKey: CVWQKEFTSSJDLS-UHFFFAOYSA-N  


Substructure search Similarity search

Network

Hover on a compound node to display the structore

Synonyms

  • 4-[2-(benzylamino)ethoxy]indolin-2-one
  • 4-[2-(benzylamino)ethoxy]-2-indolinone
  • 4-[2-(phenylmethylamino)ethoxy]-1,3-dihydroindol-2-one
  • 4-[2-(benzylamino)ethoxy]oxindole
  • 4-[2-(phenylmethylamino)ethoxy]indolin-2-one
  • 4-[2-(phenylmethylamino)ethoxy]-2-indolinone

Targets

Known targets for this compound

Species Target name Source Bibliographic reference
Rattus norvegicus Serotonin 1a (5-HT1a) receptor Starlite/ChEMBL References
Rattus norvegicus Dopamine D2 receptor Starlite/ChEMBL References
Homo sapiens dopamine receptor D4 Starlite/ChEMBL References
Rattus norvegicus Adrenergic receptor alpha-1 Starlite/ChEMBL References
Homo sapiens dopamine receptor D2 Starlite/ChEMBL References
Homo sapiens dopamine receptor D3 Starlite/ChEMBL References

Predicted pathogen targets for this compound

By orthology
Species Potential target Known druggable target/s Ortholog Group
Schistosoma japonicum Octopamine receptor, putative Get druggable targets OG5_133249 All targets in OG5_133249
Schistosoma mansoni biogenic amine (5HT) receptor Get druggable targets OG5_133249 All targets in OG5_133249
Schistosoma japonicum ko:K04153 5-hydroxytryptamine (serotonin) receptor 1A, putative Get druggable targets OG5_133249 All targets in OG5_133249
Echinococcus granulosus biogenic amine 5HT receptor Get druggable targets OG5_133249 All targets in OG5_133249
Loa Loa (eye worm) hypothetical protein Get druggable targets OG5_133249 All targets in OG5_133249
Loa Loa (eye worm) hypothetical protein Get druggable targets OG5_133249 All targets in OG5_133249
Echinococcus multilocularis serotonin receptor Get druggable targets OG5_133249 All targets in OG5_133249
Echinococcus multilocularis serotonin receptor Get druggable targets OG5_133249 All targets in OG5_133249
Schistosoma japonicum expressed protein Get druggable targets OG5_133249 All targets in OG5_133249
By sequence similarity to non orthologous known druggable targets
Species Potential target Known druggable target Length Alignment span Identity
Schistosoma japonicum ko:K04207 neuropeptide Y receptor Y5, putative Serotonin 1a (5-HT1a) receptor   422 aa 339 aa 23.0 %
Loa Loa (eye worm) hypothetical protein Serotonin 1a (5-HT1a) receptor   422 aa 388 aa 26.5 %
Schistosoma mansoni biogenic amine receptor Dopamine D2 receptor   444 aa 452 aa 30.1 %
Onchocerca volvulus Serotonin 1a (5-HT1a) receptor   422 aa 436 aa 23.9 %
Onchocerca volvulus Serotonin 1a (5-HT1a) receptor   422 aa 407 aa 23.3 %
Echinococcus granulosus g protein coupled receptor Serotonin 1a (5-HT1a) receptor   422 aa 432 aa 24.3 %
Schistosoma mansoni peptide (FMRFamide/neurokinin-3)-like receptor Serotonin 1a (5-HT1a) receptor   422 aa 350 aa 20.6 %
Schistosoma japonicum Octopamine receptor, putative Dopamine D2 receptor   444 aa 456 aa 29.4 %
Echinococcus multilocularis g protein coupled receptor Serotonin 1a (5-HT1a) receptor   422 aa 433 aa 22.4 %
Onchocerca volvulus Glycoprotein hormone beta 5 homolog Serotonin 1a (5-HT1a) receptor   422 aa 477 aa 24.3 %
Onchocerca volvulus Mitochondrial inner membrane protein homolog Serotonin 1a (5-HT1a) receptor   422 aa 383 aa 30.5 %
Echinococcus multilocularis orexin receptor type 2 Serotonin 1a (5-HT1a) receptor   422 aa 369 aa 22.2 %
Onchocerca volvulus RB1-inducible coiled-coil protein 1 homolog Dopamine D2 receptor   444 aa 474 aa 23.4 %
Echinococcus granulosus orexin receptor type 2 Serotonin 1a (5-HT1a) receptor   422 aa 369 aa 22.0 %
Schistosoma japonicum IPR000276,Rhodopsin-like GPCR superfamily,domain-containing Serotonin 1a (5-HT1a) receptor   422 aa 417 aa 21.1 %
Brugia malayi hypothetical protein dopamine receptor D3 400 aa 392 aa 19.9 %
Schistosoma japonicum ko:K04135 adrenergic receptor, alpha 1a, putative Serotonin 1a (5-HT1a) receptor   422 aa 448 aa 29.7 %
Loa Loa (eye worm) TYRA-2 protein Serotonin 1a (5-HT1a) receptor   422 aa 491 aa 27.3 %
Echinococcus granulosus biogenic amine 5HT receptor Dopamine D2 receptor   444 aa 429 aa 31.7 %
Onchocerca volvulus Serotonin 1a (5-HT1a) receptor   422 aa 390 aa 33.6 %
Echinococcus granulosus g protein coupled receptor Serotonin 1a (5-HT1a) receptor   422 aa 432 aa 23.4 %
Onchocerca volvulus Serotonin 1a (5-HT1a) receptor   422 aa 426 aa 29.6 %
Echinococcus multilocularis serotonin receptor Dopamine D2 receptor   444 aa 428 aa 31.3 %
Schistosoma mansoni muscarinic acetylcholine (GAR) receptor Dopamine D2 receptor   444 aa 487 aa 23.8 %
Echinococcus multilocularis neuropeptides capa receptor Serotonin 1a (5-HT1a) receptor   422 aa 430 aa 20.0 %
Echinococcus multilocularis g protein coupled receptor Serotonin 1a (5-HT1a) receptor   422 aa 432 aa 23.6 %
Schistosoma japonicum ko:K04136 adrenergic receptor, alpha 1b, putative Serotonin 1a (5-HT1a) receptor   422 aa 444 aa 29.3 %
Echinococcus granulosus alpha 1A adrenergic receptor Serotonin 1a (5-HT1a) receptor   422 aa 452 aa 21.0 %
Schistosoma mansoni biogenic amine (dopamine) receptor Dopamine D2 receptor   444 aa 494 aa 26.3 %
Schistosoma japonicum ko:K04145 dopamine receptor D2, putative Serotonin 1a (5-HT1a) receptor   422 aa 410 aa 27.8 %
Schistosoma japonicum IPR000276,Rhodopsin-like GPCR superfamily,domain-containing Serotonin 1a (5-HT1a) receptor   422 aa 392 aa 20.7 %
Schistosoma mansoni amine GPCR Serotonin 1a (5-HT1a) receptor   422 aa 440 aa 31.6 %
Schistosoma japonicum Octopamine receptor 1, putative Serotonin 1a (5-HT1a) receptor   422 aa 424 aa 24.3 %
Obtained from network model

Ranking Plot

Putative Targets List

Species Potential target Raw Global Species
Echinococcus multilocularis JmjC domain containing protein 4 0.0026 0.004 0.0035
Onchocerca volvulus 0.0147 0.0403 0.212
Schistosoma mansoni serine/threonine protein kinase 0.0915 0.272 0.2717
Brugia malayi protein C17H12.11 0.006 0.0142 0.0137
Schistosoma mansoni family S12 unassigned peptidase (S12 family) 0.0147 0.0403 0.0398
Echinococcus granulosus growth hormone secretagogue receptor type 1 0.0022 0.0026 0.0021
Schistosoma mansoni biogenic amine (5HT) receptor 0.0169 0.0469 0.0465
Loa Loa (eye worm) jmjC domain-containing protein 0.0026 0.004 0.0035
Leishmania major DNA polymerase eta, putative 0.0019 0.0018 0.0009
Brugia malayi AMP-binding enzyme family protein 0.0093 0.024 0.0235
Schistosoma mansoni histone-lysine n-methyltransferase setb1 0.003 0.005 0.0045
Brugia malayi Cathepsin L-like precursor 0.0046 0.0099 0.0094
Mycobacterium ulcerans acyl-CoA synthetase 0.0027 0.0043 0.0866
Brugia malayi Eukaryotic-type carbonic anhydrase family protein 0.1563 0.4677 0.4674
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0261 0.0747 0.0747
Mycobacterium tuberculosis Probable conserved lipoprotein 0.0147 0.0403 0.142
Echinococcus multilocularis g protein linked acetylcholine receptor gar 2a 0.0022 0.0026 0.0021
Echinococcus granulosus ATP dependent DNA helicase Q5 0.002 0.0021 0.0016
Trichomonas vaginalis DNA polymerase eta, putative 0.0019 0.0018 0.0192
Echinococcus granulosus c-Jun N-terminal kinases 0.0915 0.272 0.2717
Loa Loa (eye worm) hypothetical protein 0.0288 0.0829 0.0825
Brugia malayi G protein-coupled receptor F59B2.13 0.0022 0.0026 0.0021
Echinococcus multilocularis dna polymerase kappa 0.0019 0.0018 0.0013
Brugia malayi Furin-like cysteine rich region family protein 0.0299 0.0862 0.0858
Trichomonas vaginalis AGC family protein kinase 0.0037 0.0072 0.1011
Loa Loa (eye worm) hypothetical protein 0.0129 0.0349 0.0344
Trypanosoma cruzi cysteine proteinase, putative 0.0035 0.0067 0.0058
Mycobacterium tuberculosis Probable esterase LipL 0.0147 0.0403 0.142
Loa Loa (eye worm) hypothetical protein 0.0136 0.0372 0.0367
Echinococcus multilocularis roundabout 2 0.0033 0.0061 0.0056
Trypanosoma cruzi rac serine-threonine kinase, putative 0.0027 0.0041 0.0033
Echinococcus multilocularis guanine nucleotide binding protein G(s) subunit 0.009 0.0233 0.0228
Loa Loa (eye worm) matrixin family protein 0.0235 0.0669 0.0664
Brugia malayi ImpB/MucB/SamB family protein 0.0019 0.0018 0.0013
Trichomonas vaginalis AGC family protein kinase 0.0017 0.0011 0.0092
Mycobacterium leprae POSSIBLE FATTY-ACID-CoA LIGASE FADD10 (FATTY-ACID-CoA SYNTHETASE) (FATTY-ACID-CoA SYNTHASE) 0.0027 0.0043 0.0627
Loa Loa (eye worm) hypothetical protein 0.0022 0.0026 0.0021
Echinococcus granulosus g protein linked acetylcholine receptor gar 2a 0.0022 0.0026 0.0021
Trichomonas vaginalis AGC family protein kinase 0.0037 0.0072 0.1011
Trypanosoma cruzi JmjC domain, hydroxylase, putative 0.0026 0.004 0.0032
Mycobacterium tuberculosis Probable oxidoreductase 0.0116 0.0312 0.1091
Loa Loa (eye worm) steroid hormone receptor 0.0052 0.0117 0.0112
Chlamydia trachomatis DNA ligase 0.0019 0.0018 0.0624
Loa Loa (eye worm) hypothetical protein 0.1563 0.4677 0.4674
Leishmania major trypanothione reductase 0.0046 0.0099 0.0091
Echinococcus granulosus dna polymerase kappa 0.0019 0.0018 0.0013
Echinococcus granulosus serotonin receptor 0.0022 0.0026 0.0021
Schistosoma mansoni SmCL2-like peptidase (C01 family) 0.0035 0.0067 0.0062
Brugia malayi Patched family protein 0.0017 0.0013 0.0008
Loa Loa (eye worm) hypothetical protein 0.0025 0.0034 0.0029
Brugia malayi Dopamine receptor 0.0022 0.0026 0.0021
Brugia malayi Nuclear hormone receptor family member nhr-14 0.0052 0.0117 0.0112
Loa Loa (eye worm) fibroinase 0.0068 0.0167 0.0162
Echinococcus multilocularis phd:f box containing protein 0.0026 0.004 0.0035
Echinococcus granulosus enteropeptidase 0.0046 0.0099 0.0094
Brugia malayi Immunoglobulin I-set domain containing protein 0.017 0.0473 0.0468
Loa Loa (eye worm) hypothetical protein 0.0017 0.0013 0.0008
Onchocerca volvulus Protein ultraspiracle homolog 0.0052 0.0117 0.0567
Brugia malayi RE15519p 0.0022 0.0026 0.0021
Schistosoma mansoni tyrosine kinase 0.0106 0.0279 0.0275
Trypanosoma brucei DNA polymerase kappa, putative 0.0019 0.0018 0.0018
Schistosoma mansoni hypothetical protein 0.0136 0.0372 0.0367
Echinococcus multilocularis cadherin EGF LAG seven pass G type receptor 0.0063 0.0151 0.0146
Brugia malayi Patched family protein 0.0017 0.0013 0.0008
Brugia malayi Serotonin receptor 0.0022 0.0026 0.0021
Loa Loa (eye worm) beta-lactamase 0.0147 0.0403 0.0398
Brugia malayi sulfakinin receptor protein 0.0022 0.0026 0.0021
Onchocerca volvulus 0.0236 0.0672 0.3586
Loa Loa (eye worm) CMGC/GSK protein kinase 0.0051 0.0115 0.011
Schistosoma mansoni nuclear receptor 0.0025 0.0034 0.0029
Schistosoma mansoni hypothetical protein 0.0063 0.0151 0.0146
Trypanosoma brucei DNA polymerase kappa, putative 0.0019 0.0018 0.0018
Toxoplasma gondii poly(ADP-ribose) polymerase catalytic domain-containing protein 0.0019 0.0018 0.0022
Schistosoma mansoni ubiquitously transcribed sex (X/Y) chromosome tetratricopeptide repeat protein-related 0.0026 0.004 0.0035
Schistosoma mansoni biogenic amine (octopamine/dopamine) receptor 0.0022 0.0026 0.0021
Echinococcus granulosus nuclear receptor nhr 48 0.0025 0.0034 0.0029
Onchocerca volvulus 0.0142 0.0388 0.2041
Echinococcus granulosus neurotracting:lsamp:neurotrimin:obcam 0.0027 0.0043 0.0038
Echinococcus granulosus serine:threonine protein kinase PLK1 0.0097 0.0254 0.0249
Trypanosoma cruzi hypothetical protein, conserved 0.0039 0.0077 0.0069
Loa Loa (eye worm) hypothetical protein 0.0022 0.0026 0.0021
Loa Loa (eye worm) hypothetical protein 0.0069 0.0169 0.0165
Echinococcus multilocularis G protein coupled receptor 139 0.0022 0.0026 0.0021
Schistosoma mansoni nuclear hormone receptor 0.0025 0.0034 0.0029
Trypanosoma brucei carbonic anhydrase-like protein 0.3328 1 1
Trypanosoma cruzi cysteine proteinase, putative 0.0035 0.0067 0.0058
Brugia malayi putative neuropeptide receptor NPR1 0.0022 0.0026 0.0021
Loa Loa (eye worm) TKL/STKR/TYPE1 protein kinase 0.0064 0.0155 0.015
Schistosoma mansoni cathepsin F (C01 family) 0.0046 0.0099 0.0094
Brugia malayi Cathepsin L-like precursor 0.0068 0.0167 0.0162
Echinococcus granulosus activin receptor type 0.0081 0.0205 0.02
Trichomonas vaginalis CMGC family protein kinase 0.0047 0.0101 0.1436
Brugia malayi protein C24B5.3 0.0017 0.0013 0.0008
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0022 0.0026 0.0021
Mycobacterium tuberculosis Possible fatty-acid-CoA ligase FadD10 (fatty-acid-CoA synthetase) (fatty-acid-CoA synthase) 0.0027 0.0043 0.0123
Echinococcus multilocularis cyclin dependent kinase 5 0.0047 0.0101 0.0096
Echinococcus granulosus neuroglian 0.0023 0.003 0.0025
Schistosoma mansoni tyrosine kinase 0.0299 0.0862 0.0858
Loa Loa (eye worm) hypothetical protein 0.0069 0.0169 0.0165
Brugia malayi G protein-coupled receptor 0.0022 0.0026 0.0021
Leishmania major cell division related protein kinase 2,cdc2-related kinase 0.0047 0.0101 0.0092
Leishmania major cell division protein kinase 2,cdc2-related kinase 0.0047 0.0101 0.0092
Toxoplasma gondii Acetyl-coenzyme A synthetase 2, putative 0.0027 0.0043 0.0073
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0022 0.0026 0.0021
Onchocerca volvulus 0.0022 0.0026 0.0068
Trypanosoma brucei DNA polymerase IV, putative 0.0019 0.0018 0.0018
Loa Loa (eye worm) hypothetical protein 0.0017 0.0013 0.0008
Mycobacterium tuberculosis Bifunctional enzyme MbtA: salicyl-AMP ligase (SAL-AMP ligase) + salicyl-S-ArCP synthetase 0.0027 0.0043 0.0123
Leishmania major cathepsin L-like protease 0.0261 0.0747 0.0739
Trypanosoma cruzi cysteine peptidase, putative 0.0261 0.0747 0.0739
Echinococcus granulosus cathepsin l1 0.0068 0.0167 0.0162
Trypanosoma cruzi long-chain-fatty-acid-CoA ligase, putative 0.0027 0.0043 0.0034
Echinococcus multilocularis COUP TF:Svp nuclear hormone receptor 0.0052 0.0117 0.0112
Loa Loa (eye worm) TK/ROR protein kinase 0.0047 0.0103 0.0098
Plasmodium vivax replication factor C subunit 1, putative 0.0019 0.0018 0.0255
Plasmodium falciparum acyl-CoA synthetase 0.0069 0.0169 0.0345
Trypanosoma brucei PAB1-binding protein , putative 0.0024 0.0034 0.0034
Schistosoma mansoni matrix metallopeptidase-7 (M10 family) 0.0106 0.028 0.0275
Echinococcus multilocularis serine:threonine protein kinase receptor R3 0.0075 0.0186 0.0181
Entamoeba histolytica acetyltransferase, GNAT family 0.0038 0.0075 0.0848
Schistosoma mansoni cercarial elastase (S01 family) 0.0046 0.0099 0.0094
Echinococcus multilocularis tm gpcr rhodopsin gpcr rhodopsin superfamily 0.0022 0.0026 0.0021
Echinococcus granulosus hepatocyte nuclear factor 4 alpha 0.0052 0.0117 0.0112
Loa Loa (eye worm) hypothetical protein 0.0022 0.0026 0.0021
Mycobacterium leprae POSSIBLE O-SUCCINYLBENZOIC ACID--CoA LIGASE MENE (OSB-CoA SYNTHETASE) (O-SUCCINYLBENZOATE-CoA SYNTHASE) 0.0027 0.0043 0.0627
Loa Loa (eye worm) nuclear hormone receptor family member nhr-31 0.0052 0.0117 0.0112
Echinococcus multilocularis tyrosine protein kinase lyn tyrosine protein kinase blk 0.0045 0.0095 0.009
Brugia malayi Patched related family protein 4 0.0017 0.0013 0.0008
Loa Loa (eye worm) hypothetical protein 0.0042 0.0088 0.0083
Echinococcus multilocularis ecdysone induced protein 78C 0.0052 0.0117 0.0112
Brugia malayi Nuclear hormone receptor E75 0.0025 0.0034 0.0029
Echinococcus granulosus nuclear receptor 2DBD gamma 0.0052 0.0117 0.0112
Schistosoma mansoni RAR-like nuclear receptor 0.0052 0.0117 0.0112
Loa Loa (eye worm) hypothetical protein 0.0022 0.0026 0.0021
Mycobacterium tuberculosis Probable nitrite reductase [NAD(P)H] large subunit [FAD flavoprotein] NirB 0.0105 0.0276 0.0964
Schistosoma mansoni phosphatidylserine receptor 0.0026 0.004 0.0035
Toxoplasma gondii PHD-finger domain-containing protein 0.0034 0.0063 0.0117
Loa Loa (eye worm) PHD-finger family protein 0.0034 0.0063 0.0058
Schistosoma mansoni adenoreceptor 0.0022 0.0026 0.0021
Schistosoma mansoni chromosome transmission fidelity factor 0.0019 0.0018 0.0013
Trypanosoma brucei DNA polymerase kappa, putative 0.0019 0.0018 0.0018
Loa Loa (eye worm) CAMK/MLCK protein kinase 0.0017 0.0012 0.0007
Plasmodium falciparum ataxin-2 like protein, putative 0.0024 0.0034 0.0055
Loa Loa (eye worm) TK protein kinase 0.0035 0.0066 0.0061
Loa Loa (eye worm) G-protein coupled receptor 0.0022 0.0026 0.0021
Brugia malayi Dopamine receptor protein 1 0.0022 0.0026 0.0021
Mycobacterium ulcerans O-succinylbenzoic acid--CoA ligase 0.0027 0.0043 0.0866
Onchocerca volvulus 0.0027 0.0043 0.016
Brugia malayi Patched family protein 0.0017 0.0013 0.0008
Mycobacterium ulcerans non-ribosomal peptide synthetase MbtE 0.0027 0.0043 0.0866
Loa Loa (eye worm) pigment dispersing factor receptor c 0.02 0.0563 0.0558
Leishmania major acetyl-CoA synthetase, putative 0.0027 0.0043 0.0034
Loa Loa (eye worm) PLK/PLK1 protein kinase 0.0097 0.0254 0.0249
Echinococcus granulosus cyclin dependent kinase 0.0047 0.0101 0.0096
Echinococcus multilocularis tyrosine protein kinase Fyn 0.0045 0.0095 0.009
Brugia malayi calcium-independent alpha-latrotoxin receptor 2, putative 0.0063 0.0151 0.0146
Echinococcus granulosus cysteine protease 0.0035 0.0067 0.0062
Echinococcus granulosus nuclear receptor subfamily 1 group D 0.0027 0.0043 0.0038
Echinococcus multilocularis G-protein coupled receptor, putative 0.0022 0.0026 0.0021
Echinococcus multilocularis rhodopsin orphan GPCR 0.0022 0.0026 0.0021
Trichomonas vaginalis conserved hypothetical protein 0.0124 0.0333 0.492
Brugia malayi Nuclear hormone receptor family member nhr-49 0.0052 0.0117 0.0112
Loa Loa (eye worm) cysteine protease 0.0068 0.0167 0.0162
Plasmodium vivax cysteine repeat modular protein 1, putative 0.0039 0.0077 0.1745
Toxoplasma gondii cathepsin CPL 0.0068 0.0167 0.0339
Onchocerca volvulus 0.0022 0.0026 0.0068
Onchocerca volvulus 0.0027 0.0043 0.016
Loa Loa (eye worm) TYRA-2 protein 0.0022 0.0026 0.0021
Onchocerca volvulus 0.0027 0.0043 0.016
Loa Loa (eye worm) nuclear receptor NHR-67 0.0025 0.0034 0.0029
Echinococcus multilocularis jumonji domain containing 1A 0.0026 0.004 0.0035
Trichomonas vaginalis AGC family protein kinase 0.0037 0.0072 0.1011
Trypanosoma brucei DNA polymerase kappa, putative 0.0019 0.0018 0.0018
Brugia malayi Carbonic anhydrase like protein 2 precursor 0.1563 0.4677 0.4674
Schistosoma mansoni gcn5proteinral control of amino-acid synthesis 5-like 2 gcnl2 0.0141 0.0385 0.038
Schistosoma mansoni coup transcription factor 0.0052 0.0117 0.0112
Echinococcus multilocularis c src tyrosine kinase 0.0016 0.0008 0.0003
Brugia malayi hypothetical protein 0.0022 0.0026 0.0021
Loa Loa (eye worm) hypothetical protein 0.0017 0.0013 0.0008
Brugia malayi acetyl-Coenzyme A synthetase 2 0.0027 0.0043 0.0038
Brugia malayi Patched related family protein 10 0.0017 0.0013 0.0008
Echinococcus granulosus Protein patched homolog 1 0.0124 0.0333 0.0328
Brugia malayi hypothetical protein 0.0017 0.0013 0.0008
Brugia malayi hypothetical protein 0.0046 0.0099 0.0094
Echinococcus granulosus tm gpcr rhodopsin 0.0022 0.0026 0.0021
Leishmania major carbonic anhydrase-like protein 0.3328 1 1
Trichomonas vaginalis CMGC family protein kinase 0.0047 0.0101 0.1436
Schistosoma mansoni hypothetical protein 0.0063 0.0151 0.0146
Echinococcus multilocularis g protein linked acetylcholine receptor gar 2a 0.0022 0.0026 0.0021
Loa Loa (eye worm) hypothetical protein 0.0147 0.0403 0.0398
Trypanosoma brucei dihydrolipoamide dehydrogenase 0.0016 0.0008 0.0008
Brugia malayi larval opioid receptor 0.0022 0.0026 0.0021
Echinococcus granulosus tyrosine protein kinase Fyn 0.0045 0.0095 0.009
Echinococcus granulosus epidermal growth factor receptor 0.0163 0.0451 0.0447
Echinococcus granulosus pyroglutamylated rfamide peptide receptor 0.0022 0.0026 0.0021
Loa Loa (eye worm) hypothetical protein 0.0022 0.0026 0.0021
Plasmodium vivax vivapain-2 0.0068 0.0167 0.4015
Loa Loa (eye worm) hypothetical protein 0.0022 0.0026 0.0021
Echinococcus multilocularis neuropeptides capa receptor 0.0022 0.0026 0.0021
Brugia malayi cathepsin L-like cysteine proteinase, identical 0.0023 0.0029 0.0024
Leishmania major cathepsin L-like protease 0.0261 0.0747 0.0739
Brugia malayi nuclear hormone receptor 0.0025 0.0034 0.0029
Mycobacterium ulcerans non-ribosomal peptide synthetase MbtF 0.0027 0.0043 0.0866
Echinococcus multilocularis Glutaredoxin protein 5 0.002 0.0022 0.0017
Brugia malayi Patched family protein 0.0017 0.0013 0.0008
Entamoeba histolytica long-chain-fatty-acid--CoA ligase, putative 0.0027 0.0043 0.0456
Toxoplasma gondii cell-cycle-associated protein kinase GSK, putative 0.0051 0.0115 0.0229
Echinococcus multilocularis tm gpcr rhodopsin gpcr rhodopsin superfamily 0.0022 0.0026 0.0021
Brugia malayi Trypsin family protein 0.0627 0.1851 0.1847
Echinococcus granulosus terminal deoxycytidyl transferase rev1 0.0019 0.0018 0.0013
Entamoeba histolytica protein kinase, putative 0.0037 0.0072 0.0819
Loa Loa (eye worm) RecQ helicase 0.002 0.0021 0.0016
Onchocerca volvulus 0.0022 0.0026 0.0068
Plasmodium falciparum thioredoxin reductase 0.0046 0.0099 0.0194
Onchocerca volvulus Cathepsin F homolog 0.0068 0.0167 0.0836
Schistosoma mansoni alpha-1 adrenergic receptor 0.0022 0.0026 0.0021
Trypanosoma brucei protein kinase, putative 0.0051 0.0115 0.0115
Echinococcus granulosus G protein coupled receptor 139 0.0022 0.0026 0.0021
Entamoeba histolytica cysteine proteinase, putative 0.0035 0.0067 0.0749
Entamoeba histolytica Niemann-Pick C1 protein, putative 0.0288 0.0829 1
Schistosoma mansoni tyrosine kinase 0.0045 0.0095 0.009
Brugia malayi Unidentified vitellogenin-linked transcript protein 6, putative 0.0022 0.0026 0.0021
Echinococcus granulosus carbonic anhydrase 0.1563 0.4677 0.4674
Loa Loa (eye worm) hypothetical protein 0.0022 0.0026 0.0021
Brugia malayi hypothetical protein 0.0022 0.0026 0.0021
Echinococcus multilocularis rhodopsin orphan GPCR 0.0022 0.0026 0.0021
Loa Loa (eye worm) hypothetical protein 0.0022 0.0026 0.0021
Plasmodium vivax hypothetical protein, conserved 0.0034 0.0063 0.139
Echinococcus multilocularis lipoxygenase domain containing protein 0.0035 0.0066 0.0061
Leishmania major cysteine peptidase A (CPA) 0.0068 0.0167 0.0158
Trypanosoma brucei ATP-dependent DEAD/H DNA helicase recQ, putative 0.002 0.0021 0.0021
Schistosoma mansoni cercarial elastase (S01 family) 0.0046 0.0099 0.0094
Trypanosoma brucei rac serine-threonine kinase, putative 0.0037 0.0072 0.0072
Mycobacterium tuberculosis Probable hydrolase 0.0147 0.0403 0.142
Echinococcus granulosus sodium:potassium dependent atpase beta subunit 0.002 0.0022 0.0017
Leishmania major long-chain-fatty-acid-CoA ligase, putative 0.0027 0.0043 0.0034
Toxoplasma gondii ATP-dependent DNA helicase, RecQ family protein 0.002 0.0021 0.0026
Loa Loa (eye worm) hypothetical protein 0.0017 0.0013 0.0008
Brugia malayi Eukaryotic-type carbonic anhydrase family protein 0.1563 0.4677 0.4674
Schistosoma mansoni Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) 0.009 0.0233 0.0228
Echinococcus multilocularis rhodopsin orphan GPCR 0.0022 0.0026 0.0021
Loa Loa (eye worm) hypothetical protein 0.0022 0.0026 0.0021
Loa Loa (eye worm) hypothetical protein 0.0022 0.0026 0.0021
Brugia malayi hypothetical protein 0.0019 0.0018 0.0013
Mycobacterium ulcerans acyl-CoA synthetase 0.0093 0.024 0.5878
Echinococcus multilocularis thyrotropin releasing hormone receptor 0.0022 0.0026 0.0021
Schistosoma mansoni Tr4/Tr2 (homologue) 0.0052 0.0117 0.0112
Trichomonas vaginalis Clan CA, family C1, cathepsin L or K-like cysteine peptidase 0.0068 0.0167 0.2424
Echinococcus multilocularis g-protein coupled receptor 0.0022 0.0026 0.0021
Echinococcus granulosus acetyl coenzyme A synthetase cytoplasmic 0.0027 0.0043 0.0038
Echinococcus multilocularis tyrosine protein kinase Btk29A 0.0016 0.0008 0.0003
Echinococcus granulosus Niemann Pick C1 protein 0.0412 0.1202 0.1198
Brugia malayi P38 map kinase family protein 2 0.0253 0.0723 0.0718
Echinococcus multilocularis epidermal growth factor receptor 0.0299 0.0862 0.0858
Schistosoma mansoni carbonic anhydrase-related 0.1563 0.4677 0.4674
Onchocerca volvulus Matrilysin homolog 0.0106 0.028 0.145
Loa Loa (eye worm) AMP-binding enzyme family protein 0.0027 0.0043 0.0038
Echinococcus granulosus transmembrane protease serine 3 0.0046 0.0099 0.0094
Giardia lamblia Kinase, CMGC GSK 0.0051 0.0115 0.4356
Loa Loa (eye worm) hypothetical protein 0.0022 0.0026 0.0021
Echinococcus multilocularis carbonic anhydrase 0.1563 0.4677 0.4674
Echinococcus multilocularis tyrosine protein kinase Src42A 0.0045 0.0095 0.009
Brugia malayi hypothetical protein 0.006 0.0142 0.0137
Onchocerca volvulus 0.0035 0.0066 0.029
Schistosoma mansoni cercarial elastase (S01 family) 0.0046 0.0099 0.0094
Plasmodium vivax vivapain-2 0.0068 0.0167 0.4015
Trypanosoma brucei dihydrolipoamide dehydrogenase 0.0016 0.0008 0.0008
Echinococcus granulosus macrophage colony stimulating factor 1 receptor 0.0415 0.1212 0.1208
Trypanosoma cruzi BRCA1 C Terminus (BRCT) domain containing protein, putative 0.0019 0.0018 0.001
Brugia malayi Pre-SET motif family protein 0.0207 0.0586 0.0581
Loa Loa (eye worm) GTP-binding regulatory protein Gs alpha-S chain 0.009 0.0233 0.0228
Loa Loa (eye worm) patched family protein 0.0017 0.0013 0.0008
Echinococcus multilocularis jumonji domain containing protein 0.0047 0.0104 0.0099
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0022 0.0026 0.0021
Brugia malayi Protein kinase domain containing protein 0.0045 0.0096 0.0091
Leishmania major DNA polymerase kappa, putative,DNA polymerase IV, putative 0.0019 0.0018 0.0009
Loa Loa (eye worm) hypothetical protein 0.0025 0.0034 0.0029
Trypanosoma cruzi glycogen synthase kinase 3, putative 0.0051 0.0115 0.0107
Echinococcus granulosus dna polymerase eta 0.0019 0.0018 0.0013
Schistosoma mansoni carbonic anhydrase II (carbonate dehydratase II) 0.3328 1 1
Entamoeba histolytica cysteine protease, putative 0.0035 0.0067 0.0749
Brugia malayi hypothetical protein 0.0022 0.0026 0.0021
Trypanosoma cruzi carbonic anhydrase-like protein, putative 0.3328 1 1
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0068 0.0167 0.2424
Trichomonas vaginalis CAMK family protein kinase 0.0097 0.0254 0.3733
Loa Loa (eye worm) ATP-dependent DNA helicase 0.002 0.0021 0.0016
Echinococcus multilocularis neuropeptide Y receptor 0.0022 0.0026 0.0021
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0035 0.0067 0.0067
Toxoplasma gondii propionate-CoA ligase 0.0027 0.0043 0.0073
Loa Loa (eye worm) hypothetical protein 0.0074 0.0183 0.0178
Entamoeba histolytica cysteine protease, putative 0.0035 0.0067 0.0749
Brugia malayi Cathepsin L-like precursor 0.0068 0.0167 0.0162
Schistosoma mansoni dihydrolipoamide dehydrogenase 0.0016 0.0008 0.0003
Mycobacterium tuberculosis Probable esterase/lipase LipP 0.0147 0.0403 0.142
Echinococcus granulosus FTZ F1 alpha 0.0052 0.0117 0.0112
Echinococcus granulosus dro:myosuppressin receptor 0.0022 0.0026 0.0021
Loa Loa (eye worm) hypothetical protein 0.0017 0.0013 0.0008
Entamoeba histolytica protein kinase 2, putative 0.0025 0.0035 0.0365
Trypanosoma brucei long-chain-fatty-acid-CoA ligase, putative 0.0027 0.0043 0.0043
Echinococcus multilocularis cathepsin L 0.0035 0.0067 0.0062
Loa Loa (eye worm) hypothetical protein 0.0017 0.0013 0.0008
Echinococcus granulosus melanoma receptor tyrosine protein kinase 0.0163 0.0451 0.0447
Onchocerca volvulus 0.0627 0.1851 1
Brugia malayi Fibronectin type III domain containing protein 0.0024 0.0033 0.0028
Echinococcus multilocularis matrix metallopeptidase 7 (M10 family) 0.0385 0.1121 0.1117
Brugia malayi Patched related family protein 12 0.0017 0.0013 0.0008
Loa Loa (eye worm) nuclear hormone receptor family member nhr-14 0.0052 0.0117 0.0112
Loa Loa (eye worm) hypothetical protein 0.0019 0.0018 0.0013
Schistosoma mansoni opsin-like receptor 0.0022 0.0026 0.0021
Trypanosoma cruzi DNA polymerase kappa, putative 0.0019 0.0018 0.0009
Echinococcus granulosus lysine specific demethylase 6a 0.0026 0.004 0.0035
Echinococcus granulosus neuropeptide receptor 0.0022 0.0026 0.0021
Mycobacterium tuberculosis Peptide synthetase MbtF (peptide synthase) 0.0027 0.0043 0.0123
Loa Loa (eye worm) hypothetical protein 0.0024 0.0034 0.0029
Brugia malayi Thioredoxin reductase 0.0046 0.0099 0.0094
Plasmodium falciparum carbonic anhydrase 0.1563 0.4677 1
Loa Loa (eye worm) hypothetical protein 0.0022 0.0026 0.0021
Schistosoma mansoni lipoxygenase 0.0035 0.0066 0.0061
Echinococcus multilocularis Jumonji, AT rich interactive domain 1B 0.0026 0.004 0.0035
Loa Loa (eye worm) hypothetical protein 0.0022 0.0026 0.0021
Schistosoma mansoni myosin xvIII 0.0022 0.0026 0.0021
Echinococcus multilocularis protein kinase shaggy 0.0051 0.0115 0.011
Plasmodium falciparum cysteine proteinase falcipain 2a 0.0068 0.0167 0.0339
Echinococcus granulosus tyrosine protein kinase Blk 0.0041 0.0084 0.0079
Loa Loa (eye worm) acetyltransferase 0.0141 0.0385 0.038
Schistosoma mansoni hypothetical protein 0.0046 0.0099 0.0094
Loa Loa (eye worm) hypothetical protein 0.0022 0.0026 0.0021
Loa Loa (eye worm) AGC/RSK/P70 protein kinase 0.0035 0.0066 0.0061
Loa Loa (eye worm) hypothetical protein 0.0017 0.0013 0.0008
Onchocerca volvulus 0.0027 0.0043 0.016
Loa Loa (eye worm) hypothetical protein 0.0046 0.0099 0.0094
Trichomonas vaginalis Clan CA, family C1, papain-like cysteine peptidase 0.0068 0.0167 0.2424
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0261 0.0747 0.0747
Trichomonas vaginalis conserved hypothetical protein 0.0019 0.0018 0.0202
Onchocerca volvulus Matrilysin homolog 0.0235 0.0669 0.3566
Trichomonas vaginalis CAMK family protein kinase 0.0097 0.0254 0.3733
Plasmodium vivax vivapain-3 0.0035 0.0067 0.1478
Plasmodium falciparum cysteine repeat modular protein 1 0.0039 0.0077 0.0147
Onchocerca volvulus 0.0046 0.0099 0.0467
Onchocerca volvulus 0.0022 0.0026 0.0068
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0022 0.0026 0.0021
Loa Loa (eye worm) hypothetical protein 0.0022 0.0026 0.0021
Echinococcus multilocularis tm gpcr rhodopsin gpcr rhodopsin superfamily 0.0022 0.0026 0.0021
Loa Loa (eye worm) CMGC/GSK protein kinase 0.0051 0.0115 0.011
Leishmania major hypothetical protein, conserved 0.0039 0.0077 0.0069
Loa Loa (eye worm) hypothetical protein 0.0022 0.0026 0.0021
Toxoplasma gondii AMP-binding enzyme domain-containing protein 0.0027 0.0043 0.0073
Echinococcus multilocularis hepatocyte nuclear factor 4 alpha 0.0052 0.0117 0.0112
Loa Loa (eye worm) hypothetical protein 0.0151 0.0417 0.0412
Toxoplasma gondii hypothetical protein 0.0017 0.0013 0.001
Schistosoma mansoni jumonji/arid domain-containing protein 0.0099 0.026 0.0255
Schistosoma mansoni nuclear hormone receptor 0.0025 0.0034 0.0029
Plasmodium vivax hypothetical protein, conserved 0.0147 0.0403 1
Echinococcus multilocularis neuropeptide receptor 0.0022 0.0026 0.0021
Loa Loa (eye worm) hypothetical protein 0.0025 0.0034 0.0029
Echinococcus multilocularis gcn5proteinral control of amino acid synthesis 0.0141 0.0385 0.038
Brugia malayi Trypsin-like protease protein 5 0.0046 0.0099 0.0094
Echinococcus granulosus g protein linked acetylcholine receptor gar 2a 0.0022 0.0026 0.0021
Schistosoma mansoni serine/threonine-protein kinase 0.0027 0.0041 0.0036
Plasmodium vivax JmjC domain containing protein 0.0026 0.004 0.0809
Brugia malayi Calcitonin receptor-like protein seb-1 0.02 0.0563 0.0558
Onchocerca volvulus 0.0022 0.0026 0.0068
Loa Loa (eye worm) hypothetical protein 0.0017 0.0013 0.0008
Trichomonas vaginalis CAMK family protein kinase 0.0097 0.0254 0.3733
Echinococcus granulosus tyrosine kinase 0.0041 0.0084 0.0079
Brugia malayi Cathepsin L-like precursor 0.0023 0.0029 0.0024
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0261 0.0747 0.0747
Echinococcus multilocularis c Jun NH2 terminal kinase 0.0915 0.272 0.2717
Schistosoma mansoni protein kinase 0.0161 0.0445 0.044
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0261 0.0747 0.0747
Loa Loa (eye worm) melatonin receptor type 1A 0.0022 0.0026 0.0021
Schistosoma mansoni hypothetical protein 0.0022 0.0026 0.0021
Trypanosoma cruzi hypothetical protein, conserved 0.0147 0.0403 0.0395
Loa Loa (eye worm) AGC/AKT protein kinase 0.0037 0.0072 0.0068
Schistosoma mansoni histamine-responsive GPCR (AAF21638) 0.0022 0.0026 0.0021
Echinococcus multilocularis tyrosine protein kinase Src42A 0.0035 0.0065 0.006
Trypanosoma cruzi FHA domain containing protein, putative 0.0019 0.0018 0.001
Echinococcus multilocularis atpase aaa+ type core atpase aaa type core 0.2372 0.7117 0.7115
Schistosoma mansoni biogenic amine (5HT) receptor 0.0022 0.0026 0.0021
Schistosoma mansoni neuropeptide F-like receptor 0.0022 0.0026 0.0021
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0261 0.0747 0.0747
Trichomonas vaginalis DNA polymerase IV / kappa, putative 0.0019 0.0018 0.0192
Loa Loa (eye worm) TK/INSR protein kinase 0.0099 0.0258 0.0253
Onchocerca volvulus 0.0022 0.0026 0.0068
Schistosoma mansoni opsin-like receptor 0.0022 0.0026 0.0021
Mycobacterium ulcerans acyl-CoA synthetase 0.0027 0.0043 0.0866
Onchocerca volvulus Serine\/threonine kinase homolog 0.0097 0.0254 0.1311
Schistosoma mansoni cercarial elastase (S01 family) 0.0046 0.0099 0.0094
Echinococcus granulosus tyrosine protein kinase Btk29A 0.0016 0.0008 0.0003
Brugia malayi nuclear receptor NHR-88 0.0052 0.0117 0.0112
Entamoeba histolytica cysteine protease, putative 0.0035 0.0067 0.0749
Echinococcus multilocularis cathepsin L cysteine protease 0.0068 0.0167 0.0162
Entamoeba histolytica myo-inositol monophosphatase, putative 0.008 0.0201 0.2372
Loa Loa (eye worm) hypothetical protein 0.0017 0.0013 0.0008
Brugia malayi Nuclear hormone receptor family member nhr-25 0.0052 0.0117 0.0112
Trichomonas vaginalis Clan CA, family C1, papain-like cysteine peptidase 0.0068 0.0167 0.2424
Loa Loa (eye worm) hypothetical protein 0.0147 0.0403 0.0398
Brugia malayi beta-lactamase family protein 0.0147 0.0403 0.0398
Trypanosoma cruzi mitogen-activated protein kinase 3, putative 0.0253 0.0723 0.0715
Loa Loa (eye worm) hypothetical protein 0.0052 0.0117 0.0112
Toxoplasma gondii patched family protein 0.0017 0.0013 0.001
Brugia malayi p70 ribosomal S6 kinase beta 0.0035 0.0066 0.0061
Echinococcus multilocularis g protein coupled receptor 0.0022 0.0026 0.0021
Mycobacterium ulcerans acyl-CoA synthetase 0.0027 0.0043 0.0866
Brugia malayi hypothetical protein 0.0022 0.0026 0.0021
Leishmania major DNA polymerase kappa, putative 0.0019 0.0018 0.0009
Loa Loa (eye worm) hypothetical protein 0.0069 0.0169 0.0165
Trypanosoma cruzi DNA polymerase eta, putative 0.0019 0.0018 0.0009
Loa Loa (eye worm) unidentified vitellogenin-linked transcript protein 6 0.0022 0.0026 0.0021
Schistosoma mansoni hepatocyte nuclear factor 4-alpha (hnf-4-alpha) 0.0025 0.0034 0.0029
Schistosoma mansoni tyrosine kinase 0.0163 0.0451 0.0447
Brugia malayi Niemann-Pick C1 protein precursor 0.0288 0.0829 0.0825
Onchocerca volvulus Cathepsin L homolog 0.0068 0.0167 0.0836
Brugia malayi Patched family protein 0.0017 0.0013 0.0008
Mycobacterium tuberculosis Probable peptidoglycan hydrolase 0.0129 0.0349 0.1227
Mycobacterium leprae PROBABLE FATTY-ACID-CoA LIGASE FADD2 (FATTY-ACID-CoA SYNTHETASE) (FATTY-ACID-CoA SYNTHASE) 0.0093 0.024 0.577
Echinococcus granulosus histone acetyltransferase KAT2B 0.0137 0.0373 0.0368
Onchocerca volvulus 0.0147 0.0403 0.212
Brugia malayi Matrixin family protein 0.0256 0.0732 0.0728
Trichomonas vaginalis cat eye syndrome critical region protein 2, cscr2, putative 0.0041 0.0085 0.1203
Entamoeba histolytica cysteine protease, putative 0.0035 0.0067 0.0749
Mycobacterium tuberculosis Probable fatty-acid-CoA ligase FadD35 (fatty-acid-CoA synthetase) (fatty-acid-CoA synthase) 0.0066 0.0158 0.0539
Brugia malayi hypothetical protein 0.0025 0.0034 0.0029
Echinococcus multilocularis activin receptor type 0.0081 0.0205 0.02
Trypanosoma brucei hypothetical protein, conserved 0.0147 0.0403 0.0403
Loa Loa (eye worm) hypothetical protein 0.0022 0.0026 0.0021
Brugia malayi nuclear receptor subfamily 1, group D, member 1, putative 0.0025 0.0034 0.0029
Loa Loa (eye worm) G-protein-linked acetylcholine receptor protein 2 0.0022 0.0026 0.0021
Schistosoma mansoni retinoid-x-receptor (RXR) 0.0052 0.0117 0.0112
Loa Loa (eye worm) hypothetical protein 0.0017 0.0013 0.0008
Echinococcus granulosus 5'partial|histone lysine N methyltransferase SETDB2 0.0029 0.0047 0.0042
Echinococcus multilocularis replication factor c subunit 1 0.0019 0.0018 0.0013
Brugia malayi beta-lactamase 0.0147 0.0403 0.0398
Loa Loa (eye worm) hypothetical protein 0.0025 0.0034 0.0029
Mycobacterium tuberculosis Conserved hypothetical protein 0.0019 0.0018 0.0034
Toxoplasma gondii kringle domain-containing protein 0.0039 0.0077 0.0147
Trypanosoma brucei cdc2-related kinase 1 0.0047 0.0101 0.0101
Brugia malayi Patched family protein 0.0017 0.0013 0.0008
Brugia malayi MH2 domain containing protein 0.014 0.0382 0.0377
Mycobacterium tuberculosis Fatty-acid-CoA synthetase FadD17 (fatty-acid-CoA synthase) (fatty-acid-CoA ligase) 0.0027 0.0043 0.0123
Onchocerca volvulus 0.0068 0.0167 0.0836
Brugia malayi G-protein-linked acetylcholine receptor protein 2, putative 0.0022 0.0026 0.0021
Loa Loa (eye worm) CMGC/MAPK/JNK protein kinase 0.0915 0.272 0.2717
Echinococcus multilocularis tyrosine protein kinase lyn lyn a protein tyrosine kinase lymphocyte specific protein tyrosine kinase 0.0045 0.0095 0.009
Echinococcus multilocularis neuropeptide receptor 0.0022 0.0026 0.0021
Entamoeba histolytica acyl-coA synthetase, putative 0.0093 0.024 0.2854
Leishmania major cathepsin L-like protease 0.0261 0.0747 0.0739
Trichomonas vaginalis Clan CA, family C1, papain-like cysteine peptidase 0.0068 0.0167 0.2424
Schistosoma mansoni subfamily S1A unassigned peptidase (S01 family) 0.0046 0.0099 0.0094
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0035 0.0067 0.0067
Brugia malayi ORL1-like opioid receptor 0.0022 0.0026 0.0021
Echinococcus granulosus biogenic amine 5HT receptor 0.0169 0.0469 0.0465
Echinococcus granulosus neuropeptide Y receptor 0.0022 0.0026 0.0021
Toxoplasma gondii histone lysine demethylase JMJC1/KDM5D/JARID1D 0.0026 0.004 0.0068
Echinococcus granulosus Immunoglobulin 0.0021 0.0023 0.0018
Trypanosoma cruzi acetyl-CoA synthetase, putative 0.0027 0.0043 0.0034
Brugia malayi Nuclear hormone receptor family member nhr-3 0.0052 0.0117 0.0112
Echinococcus multilocularis rhodopsin orphan GPCR 0.0022 0.0026 0.0021
Schistosoma mansoni hypothetical protein 0.0063 0.0151 0.0146
Loa Loa (eye worm) hypothetical protein 0.0017 0.0013 0.0008
Trichomonas vaginalis CAMK family protein kinase 0.0097 0.0254 0.3733
Schistosoma mansoni neuropeptide receptor 0.0022 0.0026 0.0021
Trypanosoma cruzi trypanothione reductase, putative 0.0046 0.0099 0.0091
Loa Loa (eye worm) hypothetical protein 0.0025 0.0034 0.0029
Echinococcus multilocularis mitogen activated protein kinase 11 0.0253 0.0723 0.0718
Echinococcus multilocularis tissue type plasminogen activator 0.0039 0.0077 0.0072
Echinococcus multilocularis nibrin 0.0019 0.0018 0.0013
Echinococcus multilocularis protein patched 0.0124 0.0333 0.0328
Echinococcus granulosus Transcription factor JmjC domain containing protein 0.017 0.0472 0.0468
Brugia malayi latrophilin 2 splice variant baaae 0.0136 0.0372 0.0367
Loa Loa (eye worm) hypothetical protein 0.0169 0.0469 0.0465
Loa Loa (eye worm) latrophilin receptor protein 2 0.0063 0.0151 0.0146
Echinococcus granulosus sterol regulatory element binding protein 0.0124 0.0333 0.0328
Onchocerca volvulus 0.0019 0.0018 0.0029
Echinococcus granulosus survival motor neuron protein 1 0.0695 0.2058 0.2054
Brugia malayi Hemopexin family protein 0.015 0.0413 0.0408
Schistosoma mansoni hypothetical protein 0.0143 0.0393 0.0388
Echinococcus multilocularis glycogen synthase kinase 3 beta 0.0051 0.0115 0.011
Loa Loa (eye worm) hypothetical protein 0.0022 0.0026 0.0021
Schistosoma mansoni histamine h1 receptor 0.0022 0.0026 0.0021
Schistosoma mansoni hypothetical protein 0.0198 0.0558 0.0553
Onchocerca volvulus 0.003 0.005 0.0201
Echinococcus multilocularis tachykinin peptides receptor 99D 0.0022 0.0026 0.0021
Plasmodium vivax histone acetyltransferase GCN5, putative 0.0041 0.0085 0.1949
Leishmania major cathepsin L-like protease 0.0068 0.0167 0.0158
Brugia malayi putative neuropeptide receptor 0.0022 0.0026 0.0021
Echinococcus granulosus neuropeptides capa receptor 0.0022 0.0026 0.0021
Trypanosoma cruzi PAB1-binding protein , putative 0.0024 0.0034 0.0025
Onchocerca volvulus Cathepsin L homolog 0.0068 0.0167 0.0836
Mycobacterium leprae possible inositol monophosphatase SubH (IMPase) (inositol-1-phosphatase) (I-1-Pase ). 0.0071 0.0175 0.4083
Onchocerca volvulus 0.0068 0.0167 0.0836
Trypanosoma cruzi cysteine protease, putative 0.0035 0.0067 0.0058
Echinococcus multilocularis rhodopsin orphan GPCR 0.0022 0.0026 0.0021
Brugia malayi hypothetical protein 0.0022 0.0026 0.0021
Onchocerca volvulus Nuclear receptor subfamily 6 group A member 1 homolog 0.0025 0.0034 0.0116
Brugia malayi Cathepsin L-like precursor 0.0068 0.0167 0.0162
Onchocerca volvulus 0.0068 0.0167 0.0836
Brugia malayi nuclear hormone receptor family member odr-7 0.0025 0.0034 0.0029
Brugia malayi Protein kinase domain containing protein 0.0047 0.0101 0.0096
Entamoeba histolytica recQ family helicase, putative 0.002 0.0021 0.0191
Echinococcus granulosus histone acetyltransferase KAT2B 0.0041 0.0085 0.008
Echinococcus granulosus neuropeptide s receptor 0.0022 0.0026 0.0021
Echinococcus multilocularis carbonic anhydrase II 0.3328 1 1
Entamoeba histolytica cysteine proteinase, putative 0.0068 0.0167 0.1962
Echinococcus granulosus epidermal growth factor receptor 0.0299 0.0862 0.0858
Echinococcus granulosus rhodopsin orphan GPCR 0.0022 0.0026 0.0021
Schistosoma mansoni survival motor neuron protein 0.0142 0.0388 0.0383
Schistosoma mansoni topbp1 0.0019 0.0018 0.0013
Loa Loa (eye worm) hypothetical protein 0.0019 0.0018 0.0013
Echinococcus multilocularis lysine specific demethylase 5A 0.0099 0.026 0.0255
Brugia malayi hypothetical protein 0.0022 0.0026 0.0021
Brugia malayi hypothetical protein 0.0025 0.0034 0.0029
Plasmodium falciparum ADP-dependent DNA helicase RecQ 0.002 0.0021 0.0026
Loa Loa (eye worm) hypothetical protein 0.0695 0.2058 0.2054
Loa Loa (eye worm) hypothetical protein 0.0106 0.028 0.0275
Loa Loa (eye worm) hypothetical protein 0.0026 0.004 0.0035
Echinococcus multilocularis Niemann Pick C1 protein 0.0412 0.1202 0.1198
Entamoeba histolytica cysteine protease, putative 0.0035 0.0067 0.0749
Echinococcus multilocularis carbonic anhydrase 0.1563 0.4677 0.4674
Trypanosoma cruzi carbonic anhydrase-like protein, putative 0.3328 1 1
Mycobacterium ulcerans beta-lactamase 0.0147 0.0403 1
Onchocerca volvulus 0.0068 0.0167 0.0836
Echinococcus granulosus tyrosine protein kinase HCK 0.0035 0.0066 0.0061
Echinococcus granulosus hypothetical protein 0.0022 0.0026 0.0021
Onchocerca volvulus 0.0022 0.0026 0.0068
Schistosoma mansoni neuropeptide F-like receptor 0.0022 0.0026 0.0021
Loa Loa (eye worm) hypothetical protein 0.0027 0.0043 0.0038
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0068 0.0167 0.2424
Echinococcus granulosus Nuclear hormone receptor family member nhr 41 0.0052 0.0117 0.0112
Trypanosoma cruzi cysteine peptidase, putative 0.0068 0.0167 0.0158
Schistosoma mansoni serine/threonine protein kinase 0.0047 0.0101 0.0096
Brugia malayi GTP-binding regulatory protein Gs alpha-S chain, putative 0.009 0.0233 0.0228
Entamoeba histolytica hypothetical protein 0.0143 0.0393 0.4705
Trichomonas vaginalis CAMK family protein kinase 0.0097 0.0254 0.3733
Plasmodium falciparum LCCL domain-containing protein 0.0035 0.0066 0.0124
Brugia malayi hypothetical protein 0.0024 0.0033 0.0028
Echinococcus multilocularis tyrosine protein kinase Abl 0.0016 0.0008 0.0003
Schistosoma mansoni glycogen synthase kinase 3-related (gsk3) (cmgc group III) 0.0051 0.0115 0.011
Echinococcus multilocularis diuretic hormone 44 receptor GPRdih2 0.0063 0.0151 0.0146
Echinococcus granulosus JmjC domain containing protein 4 0.0026 0.004 0.0035
Onchocerca volvulus 0.0149 0.041 0.2159
Onchocerca volvulus 0.0046 0.0099 0.0465
Onchocerca volvulus 0.0022 0.0026 0.0068
Entamoeba histolytica cysteine proteinase 1, putative 0.0035 0.0067 0.0749
Echinococcus granulosus matrix metallopeptidase 7 M10 family 0.0385 0.1121 0.1117
Giardia lamblia Sgs1 DNA helicase, putative 0.002 0.0021 0.0501
Loa Loa (eye worm) hypothetical protein 0.0024 0.0033 0.0028
Brugia malayi Inositol-1 0.008 0.0201 0.0196
Brugia malayi Protein kinase domain containing protein 0.0037 0.0072 0.0068
Trichomonas vaginalis penicillin-binding protein, putative 0.0147 0.0403 0.5962
Loa Loa (eye worm) hypothetical protein 0.0627 0.1851 0.1847
Brugia malayi hypothetical protein 0.0027 0.0043 0.0038
Echinococcus granulosus 5'partial|cyclin dependent kinase 1 0.0047 0.0101 0.0096
Echinococcus multilocularis subfamily S1A unassigned peptidase (S01 family) 0.0046 0.0099 0.0094
Echinococcus granulosus mitogen activated protein kinase 11 0.0253 0.0723 0.0718
Loa Loa (eye worm) hypothetical protein 0.0063 0.0151 0.0146
Trypanosoma cruzi polo-like protein kinase, putative 0.0097 0.0254 0.0246
Echinococcus granulosus RUN 0.0035 0.0066 0.0061
Loa Loa (eye worm) nuclear hormone receptor family member nhr-41 0.0052 0.0117 0.0112
Giardia lamblia PHD finger protein 15 0.0034 0.0063 0.2232
Loa Loa (eye worm) nuclear hormone receptor family member nhr-1 0.0052 0.0117 0.0112
Brugia malayi acetyltransferase, GNAT family protein 0.0141 0.0385 0.038
Trichomonas vaginalis AGC family protein kinase 0.0037 0.0072 0.1011
Trypanosoma brucei JmjC domain, hydroxylase, putative 0.0026 0.004 0.004
Schistosoma mansoni carbonic anhydrase II (carbonate dehydratase II) 0.3328 1 1
Loa Loa (eye worm) nuclear hormone receptor family member nhr-49 0.0052 0.0117 0.0112
Echinococcus multilocularis serine:threonine protein kinase PLK1 0.0097 0.0254 0.0249
Echinococcus granulosus 7TM GPCR rhodopsin 0.0022 0.0026 0.0021
Echinococcus multilocularis Mastin 0.0046 0.0099 0.0094
Entamoeba histolytica cell division protein kinase 2, putative 0.0047 0.0101 0.1162
Plasmodium falciparum RAC-beta serine/threonine protein kinase 0.0025 0.0035 0.0057
Onchocerca volvulus 0.0022 0.0026 0.0068
Onchocerca volvulus Neuropeptide F receptor homolog 0.0022 0.0026 0.0068
Schistosoma mansoni neuropeptide receptor 0.0022 0.0026 0.0021
Entamoeba histolytica cysteine protease, putative 0.0035 0.0067 0.0749
Loa Loa (eye worm) papain family cysteine protease containing protein 0.0023 0.0029 0.0024
Loa Loa (eye worm) gonadotropin-releasing hormone receptor 2 0.0022 0.0026 0.0021
Mycobacterium tuberculosis Probable dehydrogenase 0.0105 0.0276 0.0964
Brugia malayi Ligand-binding domain of nuclear hormone receptor family protein 0.0052 0.0117 0.0112
Mycobacterium ulcerans acyl-CoA synthetase 0.0027 0.0043 0.0866
Mycobacterium tuberculosis Probable peptide synthetase Nrp (peptide synthase) 0.0027 0.0043 0.0123
Brugia malayi ATP-dependent DNA helicase, RecQ family protein 0.002 0.0021 0.0016
Schistosoma mansoni niemann-pick C1 (NPC1) 0.0292 0.0843 0.0838
Echinococcus multilocularis guanine nucleotide binding protein G(s) subunit 0.009 0.0233 0.0228
Trypanosoma brucei trypanothione reductase 0.0046 0.0099 0.0099
Brugia malayi oxidoreductase, short chain dehydrogenase/reductase family protein 0.0027 0.0043 0.0038
Echinococcus multilocularis somatostatin receptor 0.0022 0.0026 0.0021
Loa Loa (eye worm) hypothetical protein 0.0022 0.0026 0.0021
Brugia malayi hypothetical protein 0.0027 0.0043 0.0038
Mycobacterium ulcerans long-chain-fatty-acid--CoA ligase 0.0027 0.0043 0.0866
Echinococcus multilocularis epidermal growth factor receptor 0.0163 0.0451 0.0447
Schistosoma mansoni amine GPCR 0.0022 0.0026 0.0021
Loa Loa (eye worm) hypothetical protein 0.0017 0.0013 0.0008
Entamoeba histolytica cysteine protease, putative 0.0035 0.0067 0.0749
Trichomonas vaginalis Clan CA, family C1, papain-like cysteine peptidase 0.0068 0.0167 0.2424
Entamoeba histolytica serine/threonine protein kinase, putative 0.0097 0.0254 0.3022
Echinococcus granulosus dihydrolipoamide dehydrogenase 0.0016 0.0008 0.0003
Plasmodium vivax acetyl-CoA synthetase, putative 0.0027 0.0043 0.0866
Echinococcus granulosus FTZ F1 nuclear receptor protein 0.0052 0.0117 0.0112
Schistosoma mansoni tyrosine kinase 0.0163 0.0451 0.0447
Trypanosoma cruzi cysteine peptidase, putative 0.0035 0.0067 0.0058
Mycobacterium leprae DIHYDROLIPOAMIDE DEHYDROGENASE LPD (LIPOAMIDE REDUCTASE (NADH)) (LIPOYL DEHYDROGENASE) (DIHYDROLIPOYL DEHYDROGENASE) (DIAPHORASE 0.0116 0.0312 0.7627
Loa Loa (eye worm) hypothetical protein 0.0627 0.1851 0.1847
Schistosoma mansoni terminal deoxycytidyl transferase 0.0019 0.0018 0.0013
Loa Loa (eye worm) ctsf protein 0.0068 0.0167 0.0162
Schistosoma mansoni cercarial elastase (S01 family) 0.0046 0.0099 0.0094
Plasmodium falciparum cysteine proteinase falcipain 3 0.0068 0.0167 0.0339
Mycobacterium ulcerans acyl-CoA synthetase 0.0027 0.0043 0.0866
Loa Loa (eye worm) hypothetical protein 0.0022 0.0026 0.0021
Echinococcus multilocularis neuropeptides capa receptor 0.0022 0.0026 0.0021
Onchocerca volvulus 0.0046 0.0099 0.0467
Echinococcus granulosus somatostatin receptor 0.0022 0.0026 0.0021
Schistosoma mansoni cathepsin s 0.0023 0.0029 0.0024
Echinococcus multilocularis Mitotic checkpoint protein PRCC, C terminal 0.0132 0.036 0.0355
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0035 0.0067 0.0925
Echinococcus granulosus carbonic anhydrase 0.1563 0.4677 0.4674
Echinococcus multilocularis peregrin 0.0038 0.0074 0.0069
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0068 0.0167 0.2424
Schistosoma mansoni DNA helicase recq5 0.002 0.0021 0.0016
Loa Loa (eye worm) TK/EGFR protein kinase 0.0299 0.0862 0.0858
Leishmania major acetyl-CoA synthetase, putative 0.0027 0.0043 0.0034
Brugia malayi Patched family protein 0.0017 0.0013 0.0008
Echinococcus multilocularis serotonin receptor 0.0169 0.0469 0.0465
Loa Loa (eye worm) hypothetical protein 0.0025 0.0034 0.0029
Echinococcus multilocularis ATP dependent DNA helicase Q5 0.002 0.0021 0.0016
Trichomonas vaginalis Clan CA, family C1, papain-like cysteine peptidase 0.0068 0.0167 0.2424
Plasmodium falciparum glycogen synthase kinase 3 0.0051 0.0115 0.0229
Loa Loa (eye worm) hypothetical protein 0.0019 0.0018 0.0013
Onchocerca volvulus 0.0046 0.0099 0.0467
Loa Loa (eye worm) hypothetical protein 0.0027 0.0043 0.0038
Loa Loa (eye worm) hypothetical protein 0.0017 0.0013 0.0008
Schistosoma mansoni nuclear receptor nhr-48 0.0025 0.0034 0.0029
Schistosoma mansoni polycystin 1-related 0.0125 0.0337 0.0332
Schistosoma mansoni tyrosine kinase 0.0156 0.0433 0.0428
Loa Loa (eye worm) hypothetical protein 0.006 0.0142 0.0137
Trichomonas vaginalis AGC family protein kinase 0.0037 0.0072 0.1011
Schistosoma mansoni tyrosine kinase 0.0156 0.0433 0.0428
Loa Loa (eye worm) TK protein kinase 0.0041 0.0084 0.0079
Mycobacterium leprae Probable lipase LipE 0.0147 0.0403 1
Brugia malayi Trypsin family protein 0.0046 0.0099 0.0094
Trichomonas vaginalis conserved hypothetical protein 0.0019 0.0018 0.0202
Brugia malayi DKFZp564C0469 protein 0.0019 0.0018 0.0013
Loa Loa (eye worm) jmjC domain-containing protein 0.007 0.0173 0.0168
Loa Loa (eye worm) hypothetical protein 0.0019 0.0018 0.0013
Echinococcus granulosus tachykinin peptides receptor 99D 0.0022 0.0026 0.0021
Mycobacterium ulcerans acyl-CoA synthetase 0.0093 0.024 0.5878
Loa Loa (eye worm) hypothetical protein 0.0017 0.0013 0.0008
Schistosoma mansoni muscarinic acetylcholine (GAR) receptor 0.0022 0.0026 0.0021
Echinococcus multilocularis biogenic amine (5HT) receptor 0.0022 0.0026 0.0021
Echinococcus multilocularis fmrfamide receptor 0.0022 0.0026 0.0021
Schistosoma mansoni cercarial elastase (S01 family) 0.0046 0.0099 0.0094
Schistosoma mansoni biogenic amine receptor 0.0022 0.0026 0.0021
Mycobacterium tuberculosis Phenyloxazoline synthase MbtB (phenyloxazoline synthetase) 0.0027 0.0043 0.0123
Echinococcus granulosus g-protein coupled receptor 0.0022 0.0026 0.0021
Schistosoma mansoni steroid hormone receptor ad4bp 0.0052 0.0117 0.0112
Brugia malayi intracellular kinase 0.0051 0.0115 0.011
Echinococcus multilocularis cysteine protease 0.0068 0.0167 0.0162
Echinococcus multilocularis serotonin receptor 0.0169 0.0469 0.0465
Loa Loa (eye worm) doublecortin family protein 0.0035 0.0066 0.0061
Brugia malayi Dopamine receptor protein 2 0.0022 0.0026 0.0021
Echinococcus multilocularis FTZ F1 alpha 0.0052 0.0117 0.0112
Mycobacterium ulcerans peptide synthetase Nrp (peptide synthase) 0.0027 0.0043 0.0866
Loa Loa (eye worm) oxidoreductase 0.0027 0.0043 0.0038
Brugia malayi Serotonin receptor 0.0022 0.0026 0.0021
Loa Loa (eye worm) hypothetical protein 0.0019 0.0018 0.0013
Brugia malayi Myosin head containing protein 0.0017 0.0013 0.0008
Brugia malayi hypothetical protein 0.0024 0.0034 0.0029
Echinococcus granulosus nervana 2 0.002 0.0022 0.0017
Brugia malayi Trypsin family protein 0.0046 0.0099 0.0094
Loa Loa (eye worm) hypothetical protein 0.016 0.0443 0.0438
Loa Loa (eye worm) hypothetical protein 0.0052 0.0117 0.0112
Onchocerca volvulus Alhambra homolog 0.0034 0.0063 0.0273
Loa Loa (eye worm) hypothetical protein 0.0022 0.0026 0.0021
Echinococcus multilocularis rhodopsin orphan GPCR 0.0022 0.0026 0.0021
Plasmodium falciparum replication factor C subunit 1, putative 0.0019 0.0018 0.0022
Brugia malayi Bloom's syndrome protein homolog 0.002 0.0021 0.0016
Entamoeba histolytica cysteine proteinase, putative 0.0035 0.0067 0.0749
Loa Loa (eye worm) eukaryotic-type carbonic anhydrase 0.3328 1 1
Trypanosoma cruzi cdc2-related kinase 1 0.0047 0.0101 0.0092
Mycobacterium ulcerans long-chain-fatty-acid-CoA ligase 0.0093 0.024 0.5878
Echinococcus granulosus glycogen synthase kinase 3 beta 0.0051 0.0115 0.011
Echinococcus multilocularis Basic leucine zipper (bZIP) transcription 0.0143 0.0393 0.0388
Trichomonas vaginalis myo inositol monophosphatase, putative 0.008 0.0201 0.2931
Echinococcus multilocularis 0.0091 0.0235 0.023
Loa Loa (eye worm) hypothetical protein 0.0027 0.0043 0.0038
Echinococcus granulosus g protein coupled receptor 0.0022 0.0026 0.0021
Brugia malayi Pax transcription activation domain interacting protein 0.0019 0.0018 0.0013
Onchocerca volvulus 0.0022 0.0026 0.0068
Loa Loa (eye worm) hypothetical protein 0.0022 0.0026 0.0021
Loa Loa (eye worm) hypothetical protein 0.0147 0.0403 0.0398
Leishmania major mitogen-activated protein kinase 3, putative,map kinase 3, putative 0.0253 0.0723 0.0715
Echinococcus granulosus bloom syndrome protein 0.002 0.0021 0.0016
Loa Loa (eye worm) hypothetical protein 0.0046 0.0099 0.0094
Echinococcus granulosus lipoxygenase domain containing protein 0.0035 0.0066 0.0061
Schistosoma mansoni subfamily S1A unassigned peptidase (S01 family) 0.0046 0.0099 0.0094
Echinococcus multilocularis fmrfamide receptor 0.0022 0.0026 0.0021
Toxoplasma gondii histone lysine demethylase JMJD6a 0.0026 0.004 0.0068
Brugia malayi Cathepsin L-like precursor 0.0068 0.0167 0.0162
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0068 0.0167 0.2424
Loa Loa (eye worm) jmjC domain-containing protein 0.0026 0.004 0.0035
Echinococcus granulosus neuropeptides capa receptor 0.0022 0.0026 0.0021
Loa Loa (eye worm) hypothetical protein 0.0052 0.0117 0.0112
Mycobacterium leprae PROBABLE NADH DEHYDROGENASE NDH 0.0105 0.0276 0.671
Mycobacterium tuberculosis Possible conserved lipoprotein LpqK 0.0147 0.0403 0.142
Echinococcus granulosus tyrosine protein kinase Lyn 0.0049 0.0108 0.0103
Brugia malayi hypothetical protein 0.0022 0.0026 0.0021
Entamoeba histolytica cysteine protease, putative 0.0035 0.0067 0.0749
Loa Loa (eye worm) eukaryotic-type carbonic anhydrase 0.1563 0.4677 0.4674
Schistosoma mansoni peptide (FMRFamide/neurokinin-3)-like receptor 0.0022 0.0026 0.0021
Brugia malayi Papain family cysteine protease containing protein 0.0035 0.0067 0.0062
Entamoeba histolytica cysteine proteinase, putative 0.0035 0.0067 0.0749
Brugia malayi G-protein coupled receptor 0.0022 0.0026 0.0021
Toxoplasma gondii histone lysine acetyltransferase GCN5-B 0.0041 0.0085 0.0165
Trichomonas vaginalis CAMK family protein kinase 0.0097 0.0254 0.3733
Schistosoma mansoni cercarial elastase (S01 family) 0.0046 0.0099 0.0094
Trypanosoma brucei DNA polymerase IV, putative 0.0019 0.0018 0.0018
Brugia malayi Chymotrypsin-like protease CTRL-1 precursor 0.0046 0.0099 0.0094
Schistosoma mansoni peptide (allatostatin)-like receptor 0.0022 0.0026 0.0021
Brugia malayi hypothetical protein 0.0017 0.0013 0.0008
Echinococcus granulosus histone lysine methyltransferase setb 0.003 0.005 0.0045
Entamoeba histolytica cysteine protease, putative 0.0068 0.0167 0.1962
Echinococcus multilocularis cyclin dependent kinase 1 0.0047 0.0101 0.0096
Loa Loa (eye worm) hypothetical protein 0.0017 0.0013 0.0008
Toxoplasma gondii LsmAD domain-containing protein 0.0024 0.0034 0.0055
Loa Loa (eye worm) hypothetical protein 0.0017 0.0013 0.0008
Leishmania major 4-coumarate:coa ligase-like protein 0.0093 0.024 0.0232
Echinococcus granulosus cathepsin l cysteine peptidase 0.0068 0.0167 0.0162
Schistosoma mansoni tyrosine kinase 0.0015 0.0007 0.0002
Loa Loa (eye worm) hypothetical protein 0.0022 0.0026 0.0021
Trichomonas vaginalis CMGC family protein kinase 0.0051 0.0115 0.1655
Echinococcus multilocularis insulin receptor 0.0099 0.0258 0.0253
Brugia malayi Cathepsin L-like cysteine proteinase 0.0046 0.0099 0.0094
Echinococcus multilocularis ATP dependent DNA helicase Q1 0.002 0.0021 0.0016
Trypanosoma cruzi DNA polymerase kappa, putative 0.0019 0.0018 0.0009
Mycobacterium tuberculosis PROBABLE FATTY-ACID-CoA LIGASE FADD18 (FRAGMENT) (FATTY-ACID-CoA SYNTHETASE) (FATTY-ACID-CoA SYNTHASE) 0.0023 0.0031 0.0082
Entamoeba histolytica cysteine proteinase, putative 0.0068 0.0167 0.1962
Echinococcus multilocularis enteropeptidase 0.0046 0.0099 0.0094
Echinococcus multilocularis allatostatin A receptor 0.0022 0.0026 0.0021
Trypanosoma brucei BRCA1 C Terminus (BRCT) domain containing protein, putative 0.0019 0.0018 0.0018
Brugia malayi nuclear receptor NHR-88 0.0025 0.0034 0.0029
Schistosoma mansoni matrix metallopeptidase-9 (M10 family) 0.0119 0.0319 0.0315
Brugia malayi Hypothetical 52.5 kDa protein ZK945.1 in chromosome II, putative 0.0147 0.0403 0.0398
Loa Loa (eye worm) hypothetical protein 0.0093 0.024 0.0235
Trichomonas vaginalis mercuric reductase, putative 0.0016 0.0008 0.0051
Onchocerca volvulus Steroid hormone receptor family member cnr14 homolog 0.0052 0.0117 0.0567
Schistosoma mansoni hypothetical protein 0.0119 0.032 0.0315
Echinococcus granulosus orexin receptor type 2 0.0022 0.0026 0.0021
Brugia malayi Tachykinin-like peptides receptor 99D 0.0022 0.0026 0.0021
Echinococcus granulosus fmrfamide receptor 0.0022 0.0026 0.0021
Echinococcus multilocularis neuropeptide s receptor 0.0022 0.0026 0.0021
Onchocerca volvulus 0.0039 0.0077 0.0349
Mycobacterium tuberculosis Probable chain -fatty-acid-CoA ligase FadD13 (fatty-acyl-CoA synthetase) 0.0093 0.024 0.0834
Loa Loa (eye worm) hypothetical protein 0.0147 0.0403 0.0398
Schistosoma mansoni hypothetical protein 0.0132 0.036 0.0355
Trichomonas vaginalis Clan CA, family C1, papain-like cysteine peptidase 0.0068 0.0167 0.2424
Echinococcus multilocularis terminal deoxycytidyl transferase rev1 0.0019 0.0018 0.0013
Onchocerca volvulus 0.0051 0.0115 0.0557
Trichomonas vaginalis Clan CA, family C1, papain-like cysteine peptidase 0.0068 0.0167 0.2424
Mycobacterium tuberculosis Probable fatty-acid-CoA ligase FadD7 (fatty-acid-CoA synthetase) (fatty-acid-CoA synthase) 0.0066 0.0158 0.0539
Loa Loa (eye worm) hypothetical protein 0.0022 0.0026 0.0021
Echinococcus multilocularis alpha 1A adrenergic receptor 0.0022 0.0026 0.0021
Onchocerca volvulus 0.0035 0.0066 0.029
Entamoeba histolytica cysteine proteinase, putative 0.0035 0.0067 0.0749
Wolbachia endosymbiont of Brugia malayi fructose-1,6-bisphosphatase 0.008 0.0201 0.0633
Entamoeba histolytica PH domain containing protein kinase, putative 0.0027 0.0041 0.0439
Echinococcus granulosus twitchin 0.0027 0.0043 0.0038
Loa Loa (eye worm) hypothetical protein 0.0035 0.0066 0.0061
Loa Loa (eye worm) AMP-binding enzyme family protein 0.0027 0.0043 0.0038
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0046 0.0099 0.1402
Chlamydia trachomatis acylglycerophosphoethanolamine acyltransferase 0.0069 0.0169 1
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0261 0.0747 0.0747
Mycobacterium ulcerans acyl-CoA synthetase 0.0027 0.0043 0.0866
Brugia malayi Protein kinase domain containing protein 0.0099 0.0258 0.0253
Brugia malayi Matrix metalloprotease, N-terminal domain containing protein 0.0129 0.0349 0.0344
Trypanosoma brucei dihydrolipoamide dehydrogenase, point mutation 0.0016 0.0008 0.0008
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0022 0.0026 0.0021
Echinococcus multilocularis cathepsin L cysteine protease 0.0068 0.0167 0.0162
Trichomonas vaginalis CAMK family protein kinase 0.0097 0.0254 0.3733
Toxoplasma gondii ATP-dependent DNA helicase, RecQ family protein 0.002 0.0021 0.0026
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0261 0.0747 0.0747
Echinococcus granulosus 7tm_1 domain containing protein 0.0022 0.0026 0.0021
Giardia lamblia Histone acetyltransferase GCN5 0.0038 0.0075 0.2705
Brugia malayi jmjC domain containing protein 0.0026 0.004 0.0035
Mycobacterium tuberculosis Probable fatty-acid-CoA ligase FadD3 (fatty-acid-CoA synthetase) (fatty-acid-CoA synthase) 0.0066 0.0158 0.0539
Wolbachia endosymbiont of Brugia malayi extracellular metallopeptidase 0.1021 0.3042 1
Schistosoma mansoni hypothetical protein 0.0198 0.0558 0.0553
Plasmodium vivax unspecified product 0.0023 0.0029 0.0513
Echinococcus multilocularis neuroglian 0.0023 0.003 0.0025
Toxoplasma gondii AGC kinase 0.0035 0.0066 0.0124
Plasmodium vivax glycogen synthase kinase 3, putative 0.0051 0.0115 0.2713
Brugia malayi ATP-dependent DNA helicase, RecQ family protein 0.002 0.0021 0.0016
Echinococcus granulosus mitogen activated protein kinase 14 0.0253 0.0723 0.0718
Brugia malayi jmjC domain containing protein 0.0026 0.004 0.0035
Loa Loa (eye worm) pre-SET domain-containing protein family protein 0.0207 0.0586 0.0581
Schistosoma mansoni hypothetical protein 0.0142 0.0388 0.0383
Loa Loa (eye worm) hypothetical protein 0.02 0.0563 0.0558
Onchocerca volvulus Bile acid receptor homolog 0.0052 0.0117 0.0567
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0046 0.0099 0.1402
Loa Loa (eye worm) transcription factor SMAD2 0.014 0.0382 0.0377
Schistosoma mansoni tyrosine kinase 0.01 0.0262 0.0257
Mycobacterium tuberculosis Probable reductase 0.0105 0.0276 0.0964
Brugia malayi hypothetical protein 0.0035 0.0066 0.0061
Echinococcus multilocularis Nuclear hormone receptor HR96 0.0025 0.0034 0.0029
Echinococcus multilocularis mitogen activated protein kinase 11 0.0253 0.0723 0.0718
Mycobacterium tuberculosis Possible penicillin-binding protein 0.0937 0.2787 1
Echinococcus granulosus neuropeptide receptor 0.0022 0.0026 0.0021
Schistosoma mansoni protein kinase 0.0077 0.0192 0.0187
Loa Loa (eye worm) hypothetical protein 0.0019 0.0018 0.0013
Loa Loa (eye worm) Papain cysteine protease/cathepsin propeptide inhibitor-containing protein 0.0068 0.0167 0.0162
Onchocerca volvulus Nuclear receptor subfamily 6 group A member 1 homolog 0.0025 0.0034 0.0116
Trypanosoma cruzi cysteine peptidase, putative 0.0261 0.0747 0.0739
Toxoplasma gondii PHD-finger domain-containing protein 0.0034 0.0063 0.0117
Loa Loa (eye worm) hypothetical protein 0.0025 0.0034 0.0029
Loa Loa (eye worm) carbonic anhydrase 3 0.3328 1 1
Trypanosoma cruzi cysteine peptidase, putative 0.0023 0.0029 0.002
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0261 0.0747 0.0747
Entamoeba histolytica protein kinase, putative 0.0051 0.0115 0.134
Loa Loa (eye worm) hypothetical protein 0.0017 0.0013 0.0008
Loa Loa (eye worm) hypothetical protein 0.0034 0.0063 0.0058
Schistosoma mansoni amine GPCR 0.0022 0.0026 0.0021
Echinococcus granulosus neuropeptide FF receptor 2 0.0022 0.0026 0.0021
Schistosoma mansoni rab6-interacting 0.0035 0.0066 0.0061
Trypanosoma cruzi ATP-dependent DEAD/H DNA helicase recQ, putative 0.002 0.0021 0.0012
Trypanosoma brucei polo-like protein kinase 0.0097 0.0254 0.0254
Schistosoma mansoni proto-oncogene tyrosine-protein kinase src 0.0016 0.0008 0.0003
Brugia malayi hypothetical protein 0.016 0.0443 0.0438
Toxoplasma gondii patched family protein 0.0017 0.0013 0.001
Trypanosoma cruzi JmjC domain, hydroxylase, putative 0.0026 0.004 0.0032
Loa Loa (eye worm) patched family protein 0.0017 0.0013 0.0008
Loa Loa (eye worm) hypothetical protein 0.0046 0.0099 0.0094
Echinococcus granulosus c src tyrosine kinase 0.0016 0.0008 0.0003
Mycobacterium tuberculosis Probable lipase LipE 0.0147 0.0403 0.142
Brugia malayi Patched protein homolog 1 0.0017 0.0013 0.0008
Onchocerca volvulus 0.0068 0.0167 0.0836
Schistosoma mansoni Neurotrimin precursor (hNT) 0.0021 0.0023 0.0018
Brugia malayi beta-lactamase family protein 0.0147 0.0403 0.0398
Schistosoma mansoni retinoic acid receptor RXR 0.0052 0.0117 0.0112
Echinococcus granulosus tm gpcr rhodopsin 0.0022 0.0026 0.0021
Brugia malayi hypothetical protein 0.0022 0.0026 0.0021
Loa Loa (eye worm) hypothetical protein 0.0022 0.0026 0.0021
Loa Loa (eye worm) hypothetical protein 0.0022 0.0026 0.0021
Trypanosoma cruzi hypothetical protein, conserved 0.0019 0.0018 0.001
Echinococcus granulosus carbonic anhydrase II 0.3328 1 1
Echinococcus granulosus Polycystic kidney disease protein 0.0035 0.0066 0.0061
Echinococcus multilocularis lysine specific demethylase 6a 0.0026 0.004 0.0035
Echinococcus granulosus Basic leucine zipper bZIP transcription 0.0143 0.0393 0.0388
Echinococcus granulosus proto oncogene tyrosine protein kinase LCK 0.0045 0.0095 0.009
Brugia malayi cathepsin L-like precursor 0.0046 0.0099 0.0094
Giardia lamblia Kinase, PLK 0.0097 0.0254 1
Loa Loa (eye worm) hypothetical protein 0.0017 0.0013 0.0008
Loa Loa (eye worm) hypothetical protein 0.0022 0.0026 0.0021
Entamoeba histolytica cysteine protease, putative 0.0035 0.0067 0.0749
Plasmodium vivax SET domain protein, putative 0.003 0.005 0.1058
Brugia malayi hypothetical protein 0.0143 0.0393 0.0388
Loa Loa (eye worm) hypothetical protein 0.0022 0.0026 0.0021
Loa Loa (eye worm) hypothetical protein 0.0022 0.0026 0.0021
Schistosoma mansoni vesicular amine transporter 0.0021 0.0023 0.0018
Echinococcus multilocularis tyrosine protein kinase Src64B 0.0045 0.0095 0.009
Echinococcus granulosus Nuclear hormone receptor HR96 0.0025 0.0034 0.0029
Loa Loa (eye worm) hypothetical protein 0.0027 0.0043 0.0038
Schistosoma mansoni serine/threonine-protein kinase 0.0027 0.0041 0.0036
Echinococcus multilocularis nuclear receptor subfamily 1 group D 0.0027 0.0043 0.0038
Mycobacterium tuberculosis Possible fatty-acid-CoA ligase FadD1 (fatty-acid-CoA synthetase) (fatty-acid-CoA synthase) 0.0027 0.0043 0.0123
Loa Loa (eye worm) matrix metalloproteinase 0.0106 0.028 0.0275
Schistosoma mansoni SmCL2-like peptidase (C01 family) 0.0035 0.0067 0.0062
Schistosoma mansoni neuropeptide receptor 0.0022 0.0026 0.0021
Brugia malayi CHE-14 protein 0.0124 0.0333 0.0328
Loa Loa (eye worm) hypothetical protein 0.0022 0.0026 0.0021
Loa Loa (eye worm) hypothetical protein 0.0017 0.0013 0.0008
Schistosoma mansoni carbonic anhydrase 0.1563 0.4677 0.4674
Mycobacterium ulcerans extragenic suppressor protein SuhB 0.008 0.0201 0.4872
Echinococcus granulosus phd:f box containing protein 0.0026 0.004 0.0035
Loa Loa (eye worm) TKL/STKR/TYPE1 protein kinase 0.0163 0.0451 0.0446
Echinococcus multilocularis dro:myosuppressin receptor 0.0022 0.0026 0.0021
Trichomonas vaginalis myo inositol monophosphatase, putative 0.008 0.0201 0.2931
Brugia malayi protein-tyrosine kinase 0.0041 0.0084 0.0079
Plasmodium vivax vivapain-1 0.0035 0.0067 0.1478
Onchocerca volvulus 0.0022 0.0026 0.0068
Schistosoma mansoni phd/f-box containing protein 0.0026 0.004 0.0035
Echinococcus multilocularis Nuclear hormone receptor family member nhr 41 0.0052 0.0117 0.0112
Loa Loa (eye worm) hypothetical protein 0.0022 0.0026 0.0021
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0261 0.0747 0.0747
Trypanosoma brucei DNA polymerase kappa, putative 0.0019 0.0018 0.0018
Schistosoma mansoni jumonji domain containing protein 0.0147 0.0403 0.0398
Brugia malayi hypothetical protein 0.0695 0.2058 0.2054
Brugia malayi nuclear receptor RXR 0.0027 0.0043 0.0038
Echinococcus multilocularis tyrosine protein kinase HCK 0.0035 0.0066 0.0061
Loa Loa (eye worm) hypothetical protein 0.0052 0.0117 0.0112
Loa Loa (eye worm) hypothetical protein 0.0022 0.0026 0.0021
Loa Loa (eye worm) hypothetical protein 0.0046 0.0099 0.0094
Schistosoma mansoni inositol monophosphatase 0.008 0.0201 0.0196
Schistosoma mansoni biogenic amine (dopamine) receptor 0.0022 0.0026 0.0021
Mycobacterium ulcerans acetyl-CoA synthetase 0.0027 0.0043 0.0866
Mycobacterium tuberculosis Inositol-1-monophosphatase SuhB 0.0071 0.0175 0.0601
Giardia lamblia DINP protein human, muc B family 0.0019 0.0018 0.0383
Schistosoma mansoni rab6-interacting 0.0035 0.0066 0.0061
Echinococcus granulosus allatostatin A receptor 0.0022 0.0026 0.0021
Brugia malayi AMP-binding enzyme family protein 0.0027 0.0043 0.0038
Echinococcus granulosus cathepsin L 0.0035 0.0067 0.0062
Schistosoma mansoni FTZ-F1 nuclear receptor-like protein 0.0052 0.0117 0.0112
Echinococcus granulosus thyroid hormone receptor alpha 0.0025 0.0034 0.0029
Echinococcus granulosus geminin 0.0198 0.0558 0.0553
Mycobacterium ulcerans DNA polymerase IV 0.0019 0.0018 0.0238
Trypanosoma cruzi cysteine peptidase (N-terminal), putative 0.0035 0.0067 0.0058
Loa Loa (eye worm) hypothetical protein 0.0017 0.0013 0.0008
Trichomonas vaginalis set domain proteins, putative 0.0236 0.0672 1
Echinococcus multilocularis carbonic anhydrase 0.1563 0.4677 0.4674
Mycobacterium tuberculosis Probable fatty-acid-CoA ligase FadD2 (fatty-acid-CoA synthetase) (fatty-acid-CoA synthase) 0.0093 0.024 0.0834
Schistosoma mansoni microtubule-associated protein tau 0.0726 0.2151 0.2147
Schistosoma mansoni transcription factor LCR-F1 0.0143 0.0393 0.0388
Echinococcus granulosus GPCR family 2 0.0063 0.0151 0.0146
Loa Loa (eye worm) hypothetical protein 0.0017 0.0013 0.0008
Echinococcus granulosus diuretic hormone 44 receptor GPRdih2 0.0063 0.0151 0.0146
Entamoeba histolytica hypothetical protein 0.0019 0.0018 0.0163
Echinococcus granulosus protein kinase shaggy 0.0051 0.0115 0.011
Mycobacterium tuberculosis Probable fatty-acid-CoA ligase FadD8 (fatty-acid-CoA synthetase) (fatty-acid-CoA synthase) 0.0027 0.0043 0.0123
Trypanosoma cruzi PAB1-binding protein , putative 0.0024 0.0034 0.0025
Entamoeba histolytica cysteine protease, putative 0.0035 0.0067 0.0749
Echinococcus multilocularis neuropeptide Y receptor 0.0022 0.0026 0.0021
Trypanosoma brucei acetyl-CoA synthetase, putative 0.0027 0.0043 0.0043
Loa Loa (eye worm) inositol-1 0.008 0.0201 0.0196
Echinococcus multilocularis tyrosine protein kinase shark 0.0106 0.0279 0.0275
Schistosoma mansoni amine GPCR 0.0022 0.0026 0.0021
Echinococcus granulosus tyrosine protein kinase Src42A 0.0045 0.0095 0.009
Schistosoma mansoni Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) 0.009 0.0233 0.0228
Loa Loa (eye worm) hypothetical protein 0.0017 0.0013 0.0008
Loa Loa (eye worm) hypothetical protein 0.0093 0.024 0.0235
Schistosoma mansoni cercarial elastase (S01 family) 0.0046 0.0099 0.0094
Loa Loa (eye worm) hypothetical protein 0.0052 0.0117 0.0112
Echinococcus multilocularis histone lysine methyltransferase setb histone lysine methyltransferase eggless 0.003 0.005 0.0045
Brugia malayi Steroid receptor seven-up type 2 0.0052 0.0117 0.0112
Loa Loa (eye worm) patched family protein 0.0017 0.0013 0.0008
Entamoeba histolytica hypothetical protein 0.0143 0.0393 0.4705
Entamoeba histolytica cysteine proteinase 2 0.0035 0.0067 0.0749
Loa Loa (eye worm) hypothetical protein 0.0027 0.0043 0.0038
Mycobacterium ulcerans lipase LipD 0.0147 0.0403 1
Trichomonas vaginalis CMGC family protein kinase 0.0051 0.0115 0.1655
Echinococcus multilocularis nuclear receptor 2DBD gamma 0.0052 0.0117 0.0112
Loa Loa (eye worm) hypothetical protein 0.0023 0.0029 0.0024
Echinococcus multilocularis rhodopsin orphan GPCR 0.0022 0.0026 0.0021
Loa Loa (eye worm) CMGC/MAPK/P38 protein kinase 0.0253 0.0723 0.0718
Brugia malayi protein C24B5.3 0.0017 0.0013 0.0008
Loa Loa (eye worm) hypothetical protein 0.0017 0.0013 0.0008
Loa Loa (eye worm) hypothetical protein 0.0093 0.024 0.0235
Trypanosoma cruzi myo-inositol-1(or 4)-monophosphatase 1, putative 0.008 0.0201 0.0192
Echinococcus granulosus insulin growth factor 1 receptor beta 0.0102 0.0269 0.0264
Trypanosoma cruzi cruzipain precursor, putative 0.0023 0.0029 0.002
Schistosoma mansoni hypothetical protein 0.0119 0.032 0.0315
Brugia malayi AKH receptor 0.0022 0.0026 0.0021
Loa Loa (eye worm) follicle stimulating hormone receptor 0.0244 0.0696 0.0691
Brugia malayi Eukaryotic-type carbonic anhydrase family protein 0.1563 0.4677 0.4674
Echinococcus multilocularis microtubule associated protein 2 0.0726 0.2151 0.2147
Brugia malayi Carbonic anhydrase like protein 2 precursor 0.1563 0.4677 0.4674
Trichomonas vaginalis conserved hypothetical protein 0.0019 0.0018 0.0202
Echinococcus granulosus tyrosine protein kinase Fyn 0.0045 0.0095 0.009
Onchocerca volvulus 0.0022 0.0026 0.0068
Schistosoma mansoni DNA polymerase eta 0.0019 0.0018 0.0013
Schistosoma mansoni subfamily S1A unassigned peptidase (S01 family) 0.0046 0.0099 0.0094
Schistosoma mansoni subfamily S1A unassigned peptidase (S01 family) 0.0046 0.0099 0.0094
Entamoeba histolytica cysteine protease, putative 0.0035 0.0067 0.0749
Brugia malayi Patched family protein 0.0017 0.0013 0.0008
Schistosoma mansoni defective proboscis extension response (dpr)-related 0.0021 0.0023 0.0018
Mycobacterium leprae conserved hypothetical protein 0.0147 0.0403 1
Entamoeba histolytica hypothetical protein 0.0143 0.0393 0.4705
Schistosoma mansoni Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) 0.009 0.0233 0.0228
Wolbachia endosymbiont of Brugia malayi NAD-dependent DNA ligase, Lig 0.0019 0.0018 0.0033
Schistosoma mansoni topbp1 0.0019 0.0018 0.0013
Schistosoma mansoni cathepsin F (C01 family) 0.0068 0.0167 0.0162
Mycobacterium ulcerans NAD-dependent DNA ligase LigA 0.0019 0.0018 0.0255
Schistosoma mansoni tyrosine kinase 0.0099 0.0258 0.0253
Echinococcus granulosus subfamily S1A unassigned peptidase S01 family 0.0046 0.0099 0.0094
Echinococcus granulosus tyrosine protein kinase shark 0.0106 0.0279 0.0275
Echinococcus granulosus biogenic amine 5HT receptor 0.0022 0.0026 0.0021
Echinococcus granulosus rhodopsin orphan GPCR 0.0022 0.0026 0.0021
Trypanosoma cruzi myo-inositol-1(or 4)-monophosphatase 1, putative 0.008 0.0201 0.0192
Echinococcus multilocularis survival motor neuron protein 1 0.0695 0.2058 0.2054
Echinococcus multilocularis Niemann Pick C1 protein 0.0288 0.0829 0.0825
Echinococcus granulosus cathepsin L cysteine proteinase 0.0068 0.0167 0.0162
Echinococcus multilocularis neuropeptide receptor A26 0.0022 0.0026 0.0021
Mycobacterium tuberculosis Possible DNA-damage-inducible protein P DinP (DNA polymerase V) (pol IV 2) (DNA nucleotidyltransferase (DNA-directed)) 0.0019 0.0018 0.0034
Echinococcus granulosus cadherin EGF LAG seven pass G type receptor 0.0063 0.0151 0.0146
Brugia malayi neuropeptide F receptor 0.0022 0.0026 0.0021
Brugia malayi AMP-binding enzyme family protein 0.0093 0.024 0.0235
Brugia malayi Iron-sulfur cluster assembly accessory protein 0.0142 0.0388 0.0383
Toxoplasma gondii cell-cycle-associated protein kinase CDK, putative 0.0047 0.0101 0.0198
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0035 0.0067 0.0925
Echinococcus granulosus lipoxygenase domain containing protein 0.0035 0.0066 0.0061
Loa Loa (eye worm) hypothetical protein 0.0022 0.0026 0.0021
Entamoeba histolytica deoxycytidyl transferase, putative 0.0019 0.0018 0.0155
Schistosoma mansoni biogenic amine (dopamine) receptor 0.0022 0.0026 0.0021
Echinococcus multilocularis cathepsin l cysteine peptidase 0.0068 0.0167 0.0162
Schistosoma mansoni biogenic amine receptor 0.0022 0.0026 0.0021
Mycobacterium tuberculosis Conserved protein 0.0147 0.0403 0.142
Loa Loa (eye worm) hypothetical protein 0.0021 0.0023 0.0018
Schistosoma mansoni hypothetical protein 0.015 0.0413 0.0408
Trichomonas vaginalis inositol monophosphatase, putative 0.008 0.0201 0.2931
Echinococcus multilocularis growth hormone secretagogue receptor type 1 0.0022 0.0026 0.0021
Echinococcus multilocularis Immunoglobulin 0.0021 0.0023 0.0018
Echinococcus granulosus neuropeptide receptor A26 0.0022 0.0026 0.0021
Echinococcus multilocularis sterol regulatory element binding protein 0.0124 0.0333 0.0328
Echinococcus granulosus Nuclear hormone receptor HR96 0.0025 0.0034 0.0029
Echinococcus multilocularis nervana 2 0.002 0.0022 0.0017
Loa Loa (eye worm) hypothetical protein 0.1563 0.4677 0.4674
Echinococcus multilocularis tyrosine protein kinase Srms 0.0041 0.0084 0.0079
Trypanosoma brucei DNA polymerase kappa, putative 0.0019 0.0018 0.0018
Entamoeba histolytica protein kinase, putative 0.0037 0.0072 0.0819
Toxoplasma gondii inositol(myo)-1(or 4)-monophosphatase 2, putative 0.008 0.0201 0.0412
Loa Loa (eye worm) hypothetical protein 0.0017 0.0013 0.0008
Plasmodium falciparum histone acetyltransferase GCN5 0.0038 0.0075 0.0142
Loa Loa (eye worm) hypothetical protein 0.0022 0.0026 0.0021
Echinococcus multilocularis Peptidase S1 S6, chymotrypsin Hap 0.0046 0.0099 0.0094
Trichomonas vaginalis chromosome transmission fidelity factor, putative 0.0019 0.0018 0.0202
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0068 0.0167 0.2424
Plasmodium vivax ataxin-2 like protein, putative 0.0024 0.0034 0.0646
Brugia malayi AMP-binding enzyme family protein 0.0027 0.0043 0.0038
Echinococcus multilocularis cyclin dependent kinase 0.0047 0.0101 0.0096
Mycobacterium tuberculosis Probable membrane NADH dehydrogenase NdhA 0.0105 0.0276 0.0964
Echinococcus granulosus rhodopsin orphan GPCR 0.0022 0.0026 0.0021
Onchocerca volvulus 0.0106 0.028 0.145
Echinococcus granulosus nervana 2 0.002 0.0022 0.0017
Plasmodium falciparum glutathione reductase 0.0046 0.0099 0.0194
Giardia lamblia Kinase, CMGC CDK 0.0047 0.0101 0.3762
Echinococcus granulosus TGF-beta receptor type-1 0.0161 0.0445 0.044
Echinococcus granulosus COUP TF:Svp nuclear hormone receptor 0.0052 0.0117 0.0112
Brugia malayi nuclear hormone receptor 0.0052 0.0117 0.0112
Plasmodium vivax patched family protein, putative 0.0017 0.0013 0.0119
Schistosoma mansoni biogenic amine receptor 0.0022 0.0026 0.0021
Echinococcus granulosus replication factor c subunit 1 0.0019 0.0018 0.0013
Echinococcus multilocularis tyrosine protein kinase Fgr 0.0045 0.0095 0.009
Brugia malayi hypothetical protein 0.0035 0.0066 0.0061
Brugia malayi Nuclear hormone receptor family member nhr-41 0.0052 0.0117 0.0112
Brugia malayi Nuclear hormone receptor-like 1 0.0052 0.0117 0.0112
Echinococcus granulosus nuclear receptor 2DBD gamma 0.0052 0.0117 0.0112
Loa Loa (eye worm) glutathione reductase 0.0046 0.0099 0.0094
Loa Loa (eye worm) hypothetical protein 0.0025 0.0034 0.0029
Brugia malayi Nuclear hormone receptor-like 1 0.0027 0.0043 0.0038
Schistosoma mansoni serine/threonine protein kinase 0.0047 0.0101 0.0096
Echinococcus multilocularis dna polymerase eta 0.0019 0.0018 0.0013
Echinococcus multilocularis pyroglutamylated rfamide peptide receptor 0.0022 0.0026 0.0021
Echinococcus multilocularis serine threonine protein kinase nrc serine threonine protein kinase gad 0.0025 0.0035 0.003
Trypanosoma cruzi polo-like protein kinase, putative 0.0097 0.0254 0.0246
Schistosoma mansoni cell adhesion molecule 0.0031 0.0054 0.0049
Echinococcus multilocularis Immunoglobulin 0.0021 0.0023 0.0018
Entamoeba histolytica protein kinase domain containing protein 0.0051 0.0115 0.134
Schistosoma mansoni hypothetical protein 0.0022 0.0026 0.0021
Plasmodium falciparum cysteine proteinase falcipain 1 0.0035 0.0067 0.0125
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0022 0.0026 0.0021
Echinococcus multilocularis G protein coupled 5 hydroxytryptamine receptor 0.0022 0.0026 0.0021
Echinococcus multilocularis inositol monophosphatase 1 0.008 0.0201 0.0196
Loa Loa (eye worm) hypothetical protein 0.0017 0.0013 0.0008
Echinococcus granulosus guanine nucleotide binding protein Gs subunit 0.009 0.0233 0.0228
Brugia malayi ecdysteroid receptor 0.0052 0.0117 0.0112
Brugia malayi hypothetical protein 0.0017 0.0013 0.0008
Brugia malayi jmjC domain containing protein 0.0099 0.026 0.0255
Loa Loa (eye worm) hypothetical protein 0.0025 0.0034 0.0029
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0068 0.0167 0.2424
Trypanosoma cruzi cysteine peptidase, clan CA, family C1, cathepsin L-like, putative 0.0238 0.0678 0.067
Loa Loa (eye worm) hypothetical protein 0.0021 0.0023 0.0018
Trypanosoma cruzi hypothetical protein, conserved 0.0147 0.0403 0.0395
Schistosoma mansoni DNA helicase recq1 0.002 0.0021 0.0016
Echinococcus granulosus carbonic anhydrase 0.1563 0.4677 0.4674
Schistosoma mansoni cercarial elastase (S01 family) 0.0046 0.0099 0.0094
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0068 0.0167 0.2424
Mycobacterium tuberculosis P-hydroxybenzoyl-AMP ligase FadD22 0.0027 0.0043 0.0123
Trypanosoma brucei DNA polymerase kappa, putative 0.0019 0.0018 0.0018
Leishmania major 4-coumarate:coa ligase-like protein 0.0093 0.024 0.0232
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0068 0.0167 0.2424
Brugia malayi Bromodomain containing protein 0.0038 0.0074 0.0069
Trypanosoma cruzi cdc2-related kinase 1 0.0047 0.0101 0.0092
Schistosoma mansoni peptide (FMRFamide/somatostatin)-like receptor 0.0022 0.0026 0.0021
Schistosoma mansoni protein phosphatase 2C 0.0026 0.004 0.0035
Schistosoma mansoni amine GPCR 0.0022 0.0026 0.0021
Echinococcus multilocularis thyroid hormone receptor alpha 0.0184 0.0517 0.0512
Schistosoma mansoni hypothetical protein 0.0022 0.0026 0.0021
Entamoeba histolytica hypothetical protein 0.0143 0.0393 0.4705
Brugia malayi PHD-finger family protein 0.0034 0.0063 0.0058
Trypanosoma brucei DNA polymerase IV, putative 0.0019 0.0018 0.0018
Brugia malayi G-protein coupled receptor 0.0022 0.0026 0.0021
Trypanosoma cruzi rac serine-threonine kinase, putative 0.0025 0.0035 0.0027
Brugia malayi Latrophilin receptor protein 2 0.0063 0.0151 0.0146
Brugia malayi jmjC domain containing protein 0.0026 0.004 0.0035
Brugia malayi Nuclear hormone receptor family member nhr-19 0.0052 0.0117 0.0112
Leishmania major hypothetical protein, conserved 0.0026 0.004 0.0032
Schistosoma mansoni tyrosine kinase 0.0156 0.0433 0.0428
Schistosoma mansoni photoreceptor-specific nuclear receptor related 0.0052 0.0117 0.0112
Brugia malayi Nuclear hormone receptor family member nhr-40 0.0052 0.0117 0.0112
Mycobacterium tuberculosis Conserved protein 0.0147 0.0403 0.142
Trypanosoma brucei inositol-1(or 4)-monophosphatase 1, putative 0.008 0.0201 0.0201
Schistosoma mansoni subfamily S1A unassigned peptidase (S01 family) 0.0046 0.0099 0.0094
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0068 0.0167 0.2424
Echinococcus multilocularis bloom syndrome protein 0.002 0.0021 0.0016
Leishmania major glycogen synthase kinase, putative;with=GeneDB:LinJ18_V3.0270 0.0051 0.0115 0.0107
Schistosoma mansoni DNA ligase IV 0.0019 0.0018 0.0013
Onchocerca volvulus 0.0022 0.0026 0.0068
Echinococcus granulosus nuclear receptor 2DBD gamma 0.0025 0.0034 0.0029
Echinococcus granulosus nuclear receptor subfamily 4 group A 0.0025 0.0034 0.0029
Schistosoma mansoni nuclear hormone receptor superfamily protein-related 0.0025 0.0034 0.0029
Brugia malayi topoisomerase 0.0019 0.0018 0.0013
Loa Loa (eye worm) hypothetical protein 0.0022 0.0026 0.0021
Echinococcus multilocularis tyrosine protein kinase Fyn 0.0045 0.0095 0.009
Trypanosoma cruzi long-chain-fatty-acid-CoA ligase, putative 0.0027 0.0043 0.0034
Trypanosoma cruzi DNA polymerase kappa, putative 0.0019 0.0018 0.0009
Loa Loa (eye worm) hypothetical protein 0.0046 0.0099 0.0094
Brugia malayi hypothetical protein 0.0022 0.0026 0.0021
Echinococcus granulosus tissue type plasminogen activator 0.0039 0.0077 0.0072
Echinococcus granulosus tyrosine protein kinase Src42A 0.0035 0.0065 0.006
Schistosoma mansoni hypothetical protein 0.0034 0.0063 0.0058
Schistosoma mansoni nuclear hormone receptor nor-1/nor-2 0.0052 0.0117 0.0112
Brugia malayi bone morphogenetic protein type 1 receptor 0.0163 0.0451 0.0446
Brugia malayi Nuclear hormone receptor family member nhr-19 0.0052 0.0117 0.0112
Echinococcus granulosus inositol monophosphatase 1 0.008 0.0201 0.0196
Echinococcus granulosus defective proboscis extension response 0.0021 0.0023 0.0018
Trichomonas vaginalis Clan CA, family C1, papain-like cysteine peptidase 0.0068 0.0167 0.2424
Trichomonas vaginalis DNA helicase recq, putative 0.002 0.0021 0.0236
Onchocerca volvulus 0.0068 0.0167 0.0836
Schistosoma mansoni nuclear hormone receptor 0.0052 0.0117 0.0112
Onchocerca volvulus 0.0022 0.0026 0.0068
Brugia malayi Melatonin receptor type 1A 0.0022 0.0026 0.0021
Brugia malayi Putative carbonic anhydrase 5 precursor 0.3328 1 1
Loa Loa (eye worm) hypothetical protein 0.0124 0.0333 0.0328
Loa Loa (eye worm) hypothetical protein 0.003 0.005 0.0045
Echinococcus granulosus Jumonji AT rich interactive domain 1B 0.0026 0.004 0.0035
Loa Loa (eye worm) trypsin family protein 0.0046 0.0099 0.0094
Loa Loa (eye worm) hypothetical protein 0.0017 0.0013 0.0008
Schistosoma mansoni thyroid hormone receptor 0.0184 0.0517 0.0512
Plasmodium falciparum JmjC domain-containing protein, putative 0.0026 0.004 0.0068
Schistosoma mansoni serine/threonine protein kinase 0.0097 0.0254 0.0249
Echinococcus multilocularis cyclin dependent kinase 1 0.0047 0.0101 0.0096
Echinococcus granulosus retinoic acid receptor rxr beta a 0.0052 0.0117 0.0112
Echinococcus multilocularis mitogen activated protein kinase 14 0.0253 0.0723 0.0718
Loa Loa (eye worm) CMGC/CDK/CDK5 protein kinase 0.0047 0.0101 0.0096
Schistosoma mansoni hypothetical protein 0.0119 0.032 0.0315
Schistosoma mansoni zinc finger protein 0.0025 0.0034 0.0029
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0261 0.0747 0.0747
Echinococcus multilocularis sex peptide receptor 0.0022 0.0026 0.0021
Mycobacterium tuberculosis Conserved protein 0.0147 0.0403 0.142
Loa Loa (eye worm) SRC-1 0.0045 0.0095 0.009
Echinococcus granulosus serine threonine protein kinase nrc 0.0025 0.0035 0.003
Toxoplasma gondii histone lysine acetyltransferase GCN5-A 0.0041 0.0085 0.0165
Schistosoma mansoni family S12 unassigned peptidase (S12 family) 0.0147 0.0403 0.0398
Echinococcus granulosus jumonji domain containing 1A 0.0026 0.004 0.0035
Brugia malayi nuclear receptor NHR-67 0.0025 0.0034 0.0029
Echinococcus multilocularis protein dispatched 1 0.0141 0.0386 0.0381
Echinococcus multilocularis peptide (allatostatin:somatostatin) 0.0022 0.0026 0.0021
Echinococcus granulosus neuropeptide Y receptor 0.0022 0.0026 0.0021
Loa Loa (eye worm) jmjC domain-containing protein 0.0026 0.004 0.0035
Schistosoma mansoni rab geranylgeranyl transferase alpha subunit 0.0019 0.0018 0.0013
Brugia malayi dihydrolipoyl dehydrogenase, mitochondrial precursor, putative 0.0016 0.0008 0.0003
Leishmania major myo-inositol-1(or 4)-monophosphatase 1, putative 0.008 0.0201 0.0192
Loa Loa (eye worm) hypothetical protein 0.0147 0.0403 0.0398
Schistosoma mansoni ancient conserved domain protein 2 (cyclin m2) 0.0022 0.0026 0.0021
Schistosoma mansoni neuropeptide f receptor 76f 0.0022 0.0026 0.0021
Loa Loa (eye worm) hypothetical protein 0.0021 0.0023 0.0018
Loa Loa (eye worm) DR-78 0.0025 0.0034 0.0029
Trichomonas vaginalis bromodomain-containing protein, putative 0.0041 0.0085 0.1203
Echinococcus granulosus Mastin 0.0046 0.0099 0.0094
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0068 0.0167 0.2424
Echinococcus granulosus tm gpcr rhodopsin 0.0022 0.0026 0.0021
Brugia malayi AMP-binding enzyme family protein 0.0027 0.0043 0.0038
Brugia malayi Corticotropin releasing factor receptor 2 precursor, putative 0.02 0.0563 0.0558
Schistosoma mansoni patched 1 0.0124 0.0333 0.0328
Loa Loa (eye worm) jmjC domain-containing protein 0.0099 0.026 0.0255
Trichomonas vaginalis RNA polymerase II ctd phosphatase, putative 0.0019 0.0018 0.0202
Onchocerca volvulus 0.0093 0.024 0.1236
Echinococcus multilocularis expressed conserved protein 0.0271 0.0777 0.0772
Trichomonas vaginalis AGC family protein kinase 0.0037 0.0072 0.1011
Loa Loa (eye worm) hypothetical protein 0.0017 0.0013 0.0008
Mycobacterium ulcerans long-chain-fatty-acid--CoA ligase 0.0093 0.024 0.5878
Brugia malayi Matrixin family protein 0.0106 0.028 0.0275
Entamoeba histolytica cysteine protease, putative 0.0035 0.0067 0.0749
Schistosoma mansoni carbonic anhydrase-related 0.1563 0.4677 0.4674
Echinococcus granulosus rhodopsin orphan GPCR 0.0022 0.0026 0.0021
Plasmodium falciparum acetyl-CoA synthetase, putative 0.0027 0.0043 0.0073
Echinococcus granulosus expressed conserved protein 0.0271 0.0777 0.0772
Toxoplasma gondii ABC1 family protein 0.0147 0.0403 0.0845
Trichomonas vaginalis chromosome transmission fidelity factor, putative 0.0019 0.0018 0.0202
Loa Loa (eye worm) neuropeptide F receptor 0.0022 0.0026 0.0021
Echinococcus granulosus beta LACTamase domain containing family member 0.0147 0.0403 0.0398
Onchocerca volvulus Dopamine\/Ecdysteroid receptor homolog 0.0022 0.0026 0.0068
Loa Loa (eye worm) 5-hydroxytryptamine 2C receptor 0.0022 0.0026 0.0021
Trichomonas vaginalis CAMK family protein kinase 0.005 0.0112 0.1604
Echinococcus multilocularis rac serine:threonine kinase 0.0027 0.0041 0.0036
Echinococcus granulosus PHD finger protein rhinoceros 0.0034 0.0063 0.0058
Schistosoma mansoni hypothetical protein 0.1563 0.4677 0.4674
Schistosoma mansoni inositol monophosphatase 0.008 0.0201 0.0196
Brugia malayi Papain family cysteine protease containing protein 0.0068 0.0167 0.0162
Loa Loa (eye worm) hypothetical protein 0.0017 0.0013 0.0008
Trypanosoma cruzi DNA polymerase kappa, putative 0.0019 0.0018 0.0009
Loa Loa (eye worm) hypothetical protein 0.0017 0.0013 0.0008
Loa Loa (eye worm) hypothetical protein 0.0025 0.0034 0.0029
Trichomonas vaginalis AGC family protein kinase 0.0037 0.0072 0.1011
Schistosoma mansoni cercarial elastase (S01 family) 0.0046 0.0099 0.0094
Mycobacterium tuberculosis Fatty-acid-AMP ligase FadD30 (fatty-acid-AMP synthetase) (fatty-acid-AMP synthase) 0.0069 0.0169 0.058
Loa Loa (eye worm) hypothetical protein 0.0046 0.0099 0.0094
Plasmodium vivax thioredoxin reductase, putative 0.0046 0.0099 0.2295
Echinococcus multilocularis nuclear receptor 2DBD gamma 0.0025 0.0034 0.0029
Loa Loa (eye worm) hypothetical protein 0.0023 0.0029 0.0024
Echinococcus granulosus Mitotic checkpoint protein PRCC C terminal 0.0132 0.036 0.0355
Echinococcus multilocularis basement membrane specific heparan sulfate 0.0021 0.0023 0.0018
Echinococcus granulosus glycoprotein Antigen 5 0.0046 0.0099 0.0094
Echinococcus granulosus cyclin dependent kinase 1 0.0047 0.0101 0.0096
Loa Loa (eye worm) hypothetical protein 0.0023 0.0029 0.0024
Schistosoma mansoni carbonic anhydrase-related 0.1563 0.4677 0.4674
Trichomonas vaginalis penicillin-binding protein, putative 0.0147 0.0403 0.5962
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0068 0.0167 0.2424
Onchocerca volvulus 0.0022 0.0026 0.0068
Loa Loa (eye worm) hypothetical protein 0.0052 0.0117 0.0112
Schistosoma mansoni tyrosine kinase 0.0016 0.0008 0.0003
Trypanosoma brucei DNA polymerase kappa, putative 0.0019 0.0018 0.0018
Echinococcus granulosus cathepsin L cysteine protease 0.0035 0.0067 0.0062
Echinococcus granulosus serine/threonine protein kinase 0.0027 0.0041 0.0036
Brugia malayi ATP dependent DNA ligase C terminal region family protein 0.0019 0.0018 0.0013
Echinococcus multilocularis tyrosine protein kinase Fyn 0.0045 0.0095 0.009
Loa Loa (eye worm) hypothetical protein 0.0025 0.0034 0.0029
Trichomonas vaginalis conserved hypothetical protein 0.0019 0.0018 0.0202
Echinococcus granulosus peregrin 0.0038 0.0074 0.0069
Brugia malayi Cathepsin L-like precursor 0.0068 0.0167 0.0162
Schistosoma mansoni hypothetical protein 0.0063 0.0151 0.0146
Brugia malayi Protein kinase domain containing protein 0.0064 0.0155 0.015
Loa Loa (eye worm) nuclear hormone receptor 0.0025 0.0034 0.0029
Brugia malayi Nuclear hormone receptor-like 1 0.0027 0.0043 0.0038
Schistosoma mansoni histone-lysine n-methyltransferase suv9 0.003 0.005 0.0045
Entamoeba histolytica protein kinase, putative 0.0035 0.0066 0.0744
Loa Loa (eye worm) hypothetical protein 0.0052 0.0117 0.0112
Toxoplasma gondii thioredoxin reductase 0.0046 0.0099 0.0194
Toxoplasma gondii ATPase, AAA family protein 0.0019 0.0018 0.0022
Mycobacterium tuberculosis NAD(P)H quinone reductase LpdA 0.0116 0.0312 0.1091
Schistosoma mansoni tyrosine kinase 0.0099 0.0258 0.0253
Loa Loa (eye worm) hypothetical protein 0.0024 0.0033 0.0028
Loa Loa (eye worm) hypothetical protein 0.0027 0.0043 0.0038
Brugia malayi nuclear hormone receptor family member nhr-6 0.0025 0.0034 0.0029
Schistosoma mansoni biogenic amine (dopamine) receptor 0.0022 0.0026 0.0021
Treponema pallidum DNA ligase (lig) 0.0019 0.0018 1
Trypanosoma cruzi cdc2-related kinase 3 0.0047 0.0101 0.0092
Brugia malayi Nuclear hormone receptor family member nhr-1 0.0052 0.0117 0.0112
Schistosoma mansoni nuclear receptor 0.0025 0.0034 0.0029
Mycobacterium ulcerans hypothetical protein 0.0093 0.024 0.5878
Schistosoma mansoni thyrotropin-releasing hormone receptor 0.0022 0.0026 0.0021
Brugia malayi Trypsin family protein 0.0046 0.0099 0.0094
Loa Loa (eye worm) hypothetical protein 0.0147 0.0403 0.0398
Loa Loa (eye worm) hypothetical protein 0.0035 0.0066 0.0061
Brugia malayi Papain family cysteine protease containing protein 0.0035 0.0067 0.0062
Loa Loa (eye worm) hypothetical protein 0.0025 0.0034 0.0029
Loa Loa (eye worm) hypothetical protein 0.003 0.005 0.0045
Mycobacterium tuberculosis Probable NADH dehydrogenase Ndh 0.0105 0.0276 0.0964
Loa Loa (eye worm) hypothetical protein 0.003 0.005 0.0045
Plasmodium vivax rac-beta serine/threonine protein kinase, putative 0.0025 0.0035 0.0676
Echinococcus multilocularis mitogen activated protein kinase 14 0.0253 0.0723 0.0718
Brugia malayi Ligand-binding domain of nuclear hormone receptor family protein 0.0052 0.0117 0.0112
Brugia malayi Tyrosine-protein kinase abl-1 0.0016 0.0008 0.0003
Echinococcus granulosus 3'partial|tyrosine protein kinase Fgr 0.0045 0.0095 0.009
Plasmodium vivax glutathione reductase, putative 0.0046 0.0099 0.2295
Trypanosoma cruzi cdc2-related kinase 3 0.0047 0.0101 0.0092
Mycobacterium ulcerans esterase/lipase LipP 0.0147 0.0403 1
Loa Loa (eye worm) patched family protein 0.0017 0.0013 0.0008
Brugia malayi Dopamine receptor protein 1, putative (partial) 0.0022 0.0026 0.0021
Mycobacterium leprae Probable fatty-acid-CoA synthetase FadD22 (fatty-acid-CoA ligase) (fatty-acid-CoA synthase) 0.0027 0.0043 0.0627
Echinococcus granulosus rhodopsin orphan GPCR 0.0022 0.0026 0.0021
Schistosoma mansoni ecdysone-induced protein 78c (dr-78) 0.0027 0.0043 0.0038
Mycobacterium ulcerans fatty-acid-CoA ligase 0.0069 0.0169 0.4085
Trichomonas vaginalis D-aminoacylase, putative 0.0147 0.0403 0.5962
Loa Loa (eye worm) nuclear Hormone Receptor family member 0.0052 0.0117 0.0112
Brugia malayi jmjC domain containing protein 0.017 0.0472 0.0468
Loa Loa (eye worm) CMGC/CDK/CDC2 protein kinase 0.0047 0.0101 0.0096
Echinococcus multilocularis histone lysine N methyltransferase SETMAR 0.003 0.005 0.0045
Echinococcus multilocularis sodium:potassium dependent atpase beta subunit 0.002 0.0022 0.0017
Onchocerca volvulus 0.0147 0.0403 0.212
Plasmodium falciparum protein kinase 5 0.0047 0.0101 0.0198
Echinococcus multilocularis FTZ F1 nuclear receptor protein 0.0052 0.0117 0.0112
Schistosoma mansoni growth hormone secretagogue receptor 0.0022 0.0026 0.0021
Mycobacterium ulcerans fusion of enoyl-CoA hydratase, EchA21 and lipase, LipE 0.0147 0.0403 1
Trypanosoma brucei mitogen-activated protein kinase 3, putative 0.0253 0.0723 0.0723
Echinococcus multilocularis thioredoxin glutathione reductase 0.0046 0.0099 0.0094
Mycobacterium tuberculosis Probable medium chain fatty-acid-CoA ligase FadD14 (fatty-acid-CoA synthetase) (fatty-acid-CoA synthase) 0.0027 0.0043 0.0123
Brugia malayi AMP-binding enzyme family protein 0.0093 0.024 0.0235
Echinococcus granulosus rhodopsin orphan GPCR 0.0022 0.0026 0.0021
Echinococcus multilocularis cathepsin l cysteine peptidase 0.0068 0.0167 0.0162
Trichomonas vaginalis DNA helicase recq1, putative 0.002 0.0021 0.0236
Loa Loa (eye worm) hypothetical protein 0.0022 0.0026 0.0021
Schistosoma mansoni hypothetical protein 0.0022 0.0026 0.0021
Loa Loa (eye worm) hypothetical protein 0.0022 0.0026 0.0021
Brugia malayi Nuclear hormone receptor family member nhr-25 0.0052 0.0117 0.0112
Echinococcus multilocularis Nuclear hormone receptor HR96 0.0025 0.0034 0.0029
Brugia malayi Kringle domain containing protein 0.0039 0.0077 0.0072
Echinococcus multilocularis GPCR, family 2 0.0063 0.0151 0.0146
Echinococcus granulosus TGF beta receptor type 1 0.0161 0.0445 0.044
Plasmodium vivax unspecified product 0.0035 0.0067 0.1478
Leishmania major 4-coumarate:coa ligase-like protein 0.0093 0.024 0.0232
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0022 0.0026 0.0021
Echinococcus granulosus thyrotropin releasing hormone receptor 0.0022 0.0026 0.0021
Leishmania major hypothetical protein, conserved 0.0024 0.0034 0.0025
Brugia malayi Matrixin family protein 0.0106 0.028 0.0275
Mycobacterium ulcerans phenyloxazoline synthase MbtB 0.0027 0.0043 0.0866
Echinococcus granulosus tumor protein p63 0.1018 0.3032 0.3029
Loa Loa (eye worm) hypothetical protein 0.0019 0.0018 0.0013
Loa Loa (eye worm) hypothetical protein 0.0106 0.028 0.0275
Echinococcus multilocularis tyrosine protein kinase Blk 0.0041 0.0084 0.0079
Trichomonas vaginalis CMGC family protein kinase 0.0047 0.0101 0.1436
Trypanosoma brucei DNA polymerase kappa, putative 0.0019 0.0018 0.0018
Loa Loa (eye worm) nuclear hormone receptor family member nhr-40 0.0052 0.0117 0.0112
Brugia malayi photoreceptor-specific nuclear receptor 0.0052 0.0117 0.0112
Mycobacterium tuberculosis Probable fatty-acid-CoA ligase FadD5 (fatty-acid-CoA synthetase) (fatty-acid-CoA synthase) 0.0066 0.0158 0.0539
Schistosoma mansoni jumonji domain containing protein 0.0026 0.004 0.0035
Echinococcus multilocularis nuclear receptor 2DBD gamma 0.0052 0.0117 0.0112
Loa Loa (eye worm) matrixin family protein 0.0256 0.0732 0.0728
Brugia malayi Pre-SET motif family protein 0.003 0.005 0.0045
Mycobacterium ulcerans DNA polymerase IV 0.0019 0.0018 0.0238
Trypanosoma cruzi cysteine peptidase, putative 0.0261 0.0747 0.0739
Echinococcus granulosus Glutaredoxin protein 5 0.002 0.0022 0.0017
Trypanosoma brucei DNA polymerase kappa, putative 0.0019 0.0018 0.0018
Trichomonas vaginalis Clan CA, family C1, papain-like cysteine peptidase 0.0068 0.0167 0.2424
Echinococcus granulosus alpha 1A adrenergic receptor 0.0022 0.0026 0.0021
Schistosoma mansoni nuclear receptor 2DBD-gamma 0.0052 0.0117 0.0112
Brugia malayi jmjC domain containing protein 0.0026 0.004 0.0035
Loa Loa (eye worm) TK/KIN16 protein kinase 0.017 0.0473 0.0468
Mycobacterium ulcerans hypothetical protein 0.0046 0.0099 0.2294
Echinococcus granulosus cathepsin l1 0.0046 0.0099 0.0094
Echinococcus granulosus thioredoxin glutathione reductase 0.0046 0.0099 0.0094
Onchocerca volvulus 0.0025 0.0034 0.0116
Onchocerca volvulus 0.0581 0.1713 0.9247
Entamoeba histolytica cysteine proteinase, putative 0.0046 0.0099 0.1135
Onchocerca volvulus Matrix metalloproteinase homolog 0.0235 0.0669 0.3566
Loa Loa (eye worm) hypothetical protein 0.0022 0.0026 0.0021
Loa Loa (eye worm) hypothetical protein 0.0022 0.0026 0.0021
Brugia malayi ecdysone receptor 0.0025 0.0034 0.0029
Echinococcus granulosus tyrosine protein kinase Src64B 0.0045 0.0095 0.009
Brugia malayi Patched family protein 0.0017 0.0013 0.0008
Schistosoma mansoni histone-lysine n-methyltransferase setb1 0.003 0.005 0.0045
Echinococcus granulosus G protein coupled 5 hydroxytryptamine receptor 0.0022 0.0026 0.0021
Loa Loa (eye worm) CMGC/CDK/CDC2 protein kinase 0.0047 0.0101 0.0096
Loa Loa (eye worm) hypothetical protein 0.0169 0.0469 0.0465
Trypanosoma cruzi cruzipain precursor, putative 0.0261 0.0747 0.0739
Brugia malayi Cathepsin L-like precursor 0.0068 0.0167 0.0162
Schistosoma mansoni aminopeptidase PILS (M01 family) 0.0046 0.0099 0.0094
Mycobacterium ulcerans acyl-CoA synthetase 0.0093 0.024 0.5878
Trypanosoma brucei DNA polymerase eta, putative 0.0019 0.0018 0.0018
Mycobacterium ulcerans bifunctional enzyme MbtA: salicyl-AMP ligase (SAL-AMP ligase) + salicyl-S-ACP synthetase 0.0027 0.0043 0.0866
Trypanosoma cruzi hypothetical protein, conserved 0.0019 0.0018 0.001
Mycobacterium tuberculosis Putative ferredoxin reductase 0.0105 0.0276 0.0964
Leishmania major hypothetical protein, conserved 0.0147 0.0403 0.0395
Echinococcus granulosus jumonji domain containing protein 0.0047 0.0104 0.0099
Echinococcus granulosus ecdysone induced protein 78C 0.0052 0.0117 0.0112
Echinococcus granulosus Niemann Pick C1 protein 0.0288 0.0829 0.0825
Echinococcus granulosus calcium:calmodulin dependent protein kinase 0.0025 0.0035 0.003
Giardia lamblia Kinase, CMGC CDK 0.0047 0.0101 0.3762
Echinococcus granulosus g protein coupled receptor 0.0022 0.0026 0.0021
Echinococcus granulosus roundabout 2 0.0033 0.0061 0.0056
Loa Loa (eye worm) hypothetical protein 0.0046 0.0099 0.0094
Brugia malayi nuclear receptor RXR 0.0025 0.0034 0.0029
Echinococcus granulosus Peptidase S1 S6 chymotrypsin Hap 0.0046 0.0099 0.0094
Toxoplasma gondii patched family protein 0.0017 0.0013 0.001
Echinococcus granulosus peptide allatostatin:somatostatin 0.0022 0.0026 0.0021
Loa Loa (eye worm) beta-LACTamase domain containing family member 0.0147 0.0403 0.0398
Trichomonas vaginalis D-aminoacylase, putative 0.0147 0.0403 0.5962
Onchocerca volvulus Tyrosine kinase homolog 0.0145 0.0397 0.209
Schistosoma mansoni cercarial elastase (S01 family) 0.0046 0.0099 0.0094
Trichomonas vaginalis glutathione reductase, putative 0.0016 0.0008 0.0051
Mycobacterium tuberculosis Dihydrolipoamide dehydrogenase LpdC (lipoamide reductase (NADH)) (lipoyl dehydrogenase) (dihydrolipoyl dehydrogenase) (diaphoras 0.0116 0.0312 0.1091
Loa Loa (eye worm) nuclear hormone receptor-like 1 0.0027 0.0043 0.0038
Schistosoma mansoni hypothetical protein 0.0119 0.032 0.0315
Brugia malayi GnHR receptor homolog 0.0022 0.0026 0.0021
Onchocerca volvulus 0.0046 0.0099 0.0467
Trypanosoma brucei cdc2-related kinase 3 0.0047 0.0101 0.0101
Entamoeba histolytica protein kinase, putative 0.0035 0.0066 0.0741
Loa Loa (eye worm) hypothetical protein 0.0068 0.0167 0.0162
Echinococcus granulosus microtubule associated protein 2 0.0726 0.2151 0.2147
Echinococcus multilocularis g protein coupled receptor 0.0022 0.0026 0.0021
Onchocerca volvulus 0.0022 0.0026 0.0068
Echinococcus multilocularis TGF beta receptor type 1 0.0161 0.0445 0.044
Loa Loa (eye worm) hypothetical protein 0.0027 0.0043 0.0038
Mycobacterium ulcerans long-chain-acyl-CoA synthetase 0.0027 0.0043 0.0866
Brugia malayi ImpB/MucB/SamB family protein 0.0019 0.0018 0.0013
Giardia lamblia Replication factor C, subunit 1 0.0019 0.0018 0.0409
Loa Loa (eye worm) hypothetical protein 0.0022 0.0026 0.0021
Echinococcus multilocularis PHD finger protein rhinoceros 0.0034 0.0063 0.0058
Echinococcus multilocularis orexin receptor type 2 0.0022 0.0026 0.0021
Entamoeba histolytica Activator 1 140 kDa subunit, putative 0.0019 0.0018 0.0163
Brugia malayi Matrixin family protein 0.0106 0.028 0.0275
Echinococcus granulosus ATP dependent DNA helicase Q1 0.002 0.0021 0.0016
Mycobacterium ulcerans acyl-CoA synthetase 0.0027 0.0043 0.0866
Loa Loa (eye worm) hypothetical protein 0.0039 0.0077 0.0072
Brugia malayi Patched family protein 0.0017 0.0013 0.0008
Schistosoma mansoni bromodomain-containing nuclear protein 1 brd1 0.0034 0.0063 0.0058
Brugia malayi Nuclear hormone receptor E75 0.0025 0.0034 0.0029
Brugia malayi neuropeptide F receptor 0.0022 0.0026 0.0021
Brugia malayi Cathepsin L-like precursor 0.0046 0.0099 0.0094
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0261 0.0747 0.0747
Plasmodium falciparum phd finger protein, putative 0.0034 0.0063 0.0117
Echinococcus multilocularis neuropeptide FF receptor 2 0.0022 0.0026 0.0021
Brugia malayi tailless protein 0.0025 0.0034 0.0029
Loa Loa (eye worm) abnormal chemotaxis protein 14 0.0124 0.0333 0.0328
Mycobacterium ulcerans long-chain fatty-acid CoA ligase 0.0093 0.024 0.5878
Loa Loa (eye worm) nuclear receptor nhr-7B 0.0025 0.0034 0.0029
Brugia malayi serine/threonine-protein kinase plk-2 0.0097 0.0254 0.0249
Schistosoma mansoni hypothetical protein 0.0035 0.0066 0.0061
Brugia malayi Stress-activated protein kinase jnk-1 0.0915 0.272 0.2717
Schistosoma mansoni SmCL2-like peptidase (C01 family) 0.0035 0.0067 0.0062
Loa Loa (eye worm) hypothetical protein 0.0026 0.004 0.0035
Echinococcus multilocularis glycoprotein Antigen 5 0.0046 0.0099 0.0094
Plasmodium vivax protein kinase Crk2 0.0047 0.0101 0.2343
Leishmania major protein kinase, putative,polo-like protein kinase, putative 0.0097 0.0254 0.0246
Loa Loa (eye worm) hypothetical protein 0.0052 0.0117 0.0112
Trypanosoma cruzi Protein kinase B 0.0027 0.0041 0.0033
Mycobacterium ulcerans hydrolase 0.0129 0.0349 0.8643
Brugia malayi Serotonin/octopamine receptor family protein 7 0.0022 0.0026 0.0021
Brugia malayi gonadotropin-releasing hormone receptor 2 0.0022 0.0026 0.0021
Brugia malayi conserved hypotetical protein 0.0025 0.0034 0.0029
Toxoplasma gondii hypothetical protein 0.1563 0.4677 1
Trichomonas vaginalis CAMK family protein kinase 0.005 0.0112 0.1604
Schistosoma mansoni tyrosine kinase 0.0016 0.0008 0.0003
Echinococcus multilocularis acetyl coenzyme A synthetase, cytoplasmic 0.0027 0.0043 0.0038
Echinococcus multilocularis RUN 0.0035 0.0066 0.0061
Leishmania major ATP-dependent DEAD/H DNA helicase recQ, putative 0.002 0.0021 0.0012
Loa Loa (eye worm) hypothetical protein 0.0027 0.0043 0.0038
Plasmodium falciparum lipid/sterol:H+ symporter 0.0017 0.0013 0.001
Brugia malayi follicle stimulating hormone receptor 0.0244 0.0696 0.0691
Mycobacterium ulcerans hypothetical protein 0.0147 0.0403 1
Echinococcus granulosus cyclin dependent kinase 5 0.0047 0.0101 0.0096
Loa Loa (eye worm) hypothetical protein 0.0022 0.0026 0.0021
Echinococcus multilocularis beta LACTamase domain containing family member 0.0147 0.0403 0.0398
Trypanosoma brucei dihydrolipoyl dehydrogenase 0.0016 0.0008 0.0008
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0022 0.0026 0.0021
Echinococcus multilocularis Polycystic kidney disease protein 0.0035 0.0066 0.0061
Brugia malayi cell division control protein 2 homolog 0.0047 0.0101 0.0096
Loa Loa (eye worm) hypothetical protein 0.0017 0.0013 0.0008
Brugia malayi Patched family protein 0.0017 0.0013 0.0008
Schistosoma mansoni amine GPCR 0.0022 0.0026 0.0021
Schistosoma mansoni histone-lysine n-methyltransferase setb1 0.003 0.005 0.0045
Loa Loa (eye worm) papain family cysteine protease containing protein 0.0068 0.0167 0.0162
Echinococcus granulosus sex peptide receptor 0.0022 0.0026 0.0021
Plasmodium vivax multidomain scavenger receptor, putative 0.0035 0.0066 0.1469
Loa Loa (eye worm) hypothetical protein 0.0106 0.028 0.0275
Schistosoma mansoni acetyl-CoA synthetase 0.0027 0.0043 0.0038
Brugia malayi Patched family protein 0.0017 0.0013 0.0008
Echinococcus multilocularis proto oncogene tyrosine protein kinase LCK 0.0045 0.0095 0.009
Echinococcus granulosus g protein coupled receptor 0.0022 0.0026 0.0021
Leishmania major cathepsin L-like protease 0.0068 0.0167 0.0158
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0068 0.0167 0.2424
Schistosoma mansoni tyrosine kinase 0.0045 0.0095 0.009
Brugia malayi orphan nuclear receptor NR2E1 0.0025 0.0034 0.0029
Loa Loa (eye worm) hypothetical protein 0.0017 0.0013 0.0008
Entamoeba histolytica acyl-CoA synthetase, putative 0.0093 0.024 0.2854
Echinococcus multilocularis Transcription factor, JmjC domain containing protein 0.017 0.0472 0.0468
Loa Loa (eye worm) hypothetical protein 0.0025 0.0034 0.0029
Brugia malayi Doublecortin family protein 0.0035 0.0066 0.0061
Trichomonas vaginalis DNA helicase recq, putative 0.002 0.0021 0.0236
Echinococcus granulosus insulin receptor 0.0099 0.0258 0.0253
Echinococcus multilocularis transmembrane protease serine 3 0.0046 0.0099 0.0094
Schistosoma mansoni opsin-like receptor 0.0022 0.0026 0.0021
Brugia malayi steroid hormone receptor 0.0052 0.0117 0.0112
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0068 0.0167 0.2424
Trichomonas vaginalis conserved hypothetical protein 0.0019 0.0018 0.0202
Mycobacterium tuberculosis Peptide synthetase MbtE (peptide synthase) 0.0027 0.0043 0.0123
Echinococcus multilocularis dihydrolipoamide dehydrogenase 0.0016 0.0008 0.0003
Echinococcus multilocularis lipoxygenase domain containing protein 0.0035 0.0066 0.0061
Echinococcus multilocularis nuclear receptor nhr 48 0.0025 0.0034 0.0029
Echinococcus multilocularis geminin 0.0198 0.0558 0.0553
Echinococcus granulosus tyrosine kinase|tyrosine protein kinase Fyn 0.0041 0.0084 0.0079
Mycobacterium leprae PROBABLE FATTY-ACID-CoA LIGASE FADD7 (FATTY-ACID-CoA SYNTHETASE) (FATTY-ACID-CoA SYNTHASE) 0.0093 0.024 0.577
Entamoeba histolytica cell division protein kinase 2, putative 0.0047 0.0101 0.1162
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0068 0.0167 0.2424
Onchocerca volvulus 0.016 0.0443 0.234
Schistosoma mansoni peptide (allatostatin/somatostatin)-like receptor 0.0022 0.0026 0.0021
Schistosoma mansoni loxhd1 0.0035 0.0066 0.0061
Loa Loa (eye worm) thioredoxin reductase 0.0046 0.0099 0.0094
Schistosoma mansoni nephrin 0.0027 0.0041 0.0036
Loa Loa (eye worm) hypothetical protein 0.0069 0.0169 0.0165
Mycobacterium tuberculosis NADPH-dependent mycothiol reductase Mtr 0.0046 0.0099 0.0326
Brugia malayi hypothetical protein 0.0017 0.0013 0.0008
Loa Loa (eye worm) hypothetical protein 0.0069 0.0169 0.0165
Plasmodium vivax acyl-CoA synthetase, putative 0.0069 0.0169 0.4085
Echinococcus granulosus guanine nucleotide binding protein Gs subunit 0.009 0.0233 0.0228
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0022 0.0026 0.0021
Brugia malayi SRC-1 0.0045 0.0095 0.009
Loa Loa (eye worm) ImpB/MucB/SamB family protein 0.0019 0.0018 0.0013
Trypanosoma cruzi acetyl-CoA synthetase, putative 0.0027 0.0043 0.0034
Loa Loa (eye worm) hypothetical protein 0.0024 0.0033 0.0028
Echinococcus granulosus nibrin 0.0019 0.0018 0.0013
Trypanosoma cruzi mitogen-activated protein kinase 3, putative 0.0253 0.0723 0.0715
Toxoplasma gondii patched family protein 0.0017 0.0013 0.001
Plasmodium falciparum ATP-dependent DNA helicase Q1 0.002 0.0021 0.0026
Entamoeba histolytica PH domain containing protein kinase, putative 0.0027 0.0041 0.0439
Mycobacterium tuberculosis Probable lipase LipD 0.0147 0.0403 0.142
Trichomonas vaginalis antibiotic synthetase, putative 0.0027 0.0043 0.0563
Onchocerca volvulus 0.0136 0.0371 0.1949
Brugia malayi hypothetical protein 0.0019 0.0018 0.0013
Trypanosoma brucei unspecified product 0.0019 0.0018 0.0018
Trichomonas vaginalis antibiotic synthetase, putative 0.0027 0.0043 0.0563
Brugia malayi Immunoglobulin I-set domain containing protein 0.0024 0.0033 0.0028
Brugia malayi AMP-binding enzyme family protein 0.0027 0.0043 0.0038
Loa Loa (eye worm) hypothetical protein 0.1563 0.4677 0.4674
Onchocerca volvulus 0.0068 0.0167 0.0836
Loa Loa (eye worm) G-protein coupled receptor 0.0022 0.0026 0.0021
Echinococcus granulosus tyrosine protein kinase Fyn 0.0045 0.0095 0.009
Loa Loa (eye worm) hypothetical protein 0.0149 0.041 0.0405
Schistosoma mansoni cellular tumor antigen P53 0.0149 0.041 0.0405
Echinococcus multilocularis tyrosine protein kinase Fyn 0.0041 0.0084 0.0079
Brugia malayi Patched family protein 0.0017 0.0013 0.0008
Echinococcus multilocularis retinoic acid receptor rxr beta a retinoic acid receptor rxr alpha a retinoic acid receptor rxr alpha 0.0025 0.0034 0.0029
Trichomonas vaginalis esterase, putative 0.0147 0.0403 0.5962
Schistosoma mansoni peptide (FMRFamide/somatostatin)-like receptor 0.0022 0.0026 0.0021
Entamoeba histolytica acyl-CoA synthetase, putative 0.0093 0.024 0.2854
Giardia lamblia Kinase, CMGC GSK 0.0051 0.0115 0.4356
Entamoeba histolytica protein kinase domain containing protein 0.0051 0.0115 0.134
Leishmania major cathepsin L-like protease 0.0068 0.0167 0.0158
Trypanosoma cruzi major cysteine proteinase, putative 0.0205 0.0578 0.057
Mycobacterium ulcerans acyl-CoA synthetase 0.0027 0.0043 0.0866
Loa Loa (eye worm) patched family protein 0.0017 0.0013 0.0008
Schistosoma mansoni cathepsin F (C01 family) 0.0068 0.0167 0.0162
Trichomonas vaginalis RNA polymerase II ctd phosphatase, putative 0.0019 0.0018 0.0202
Onchocerca volvulus 0.015 0.0413 0.2176
Trichomonas vaginalis D-aminoacylase, putative 0.0147 0.0403 0.5962
Loa Loa (eye worm) hypothetical protein 0.0022 0.0026 0.0021
Schistosoma mansoni retinoid-x-receptor (RXR) 0.0027 0.0043 0.0038
Echinococcus multilocularis cysteine protease 0.0068 0.0167 0.0162
Mycobacterium leprae PROBABLE HYDROLASE 0.0129 0.0349 0.8608
Trichomonas vaginalis Clan CA, family C1, cathepsin L or K-like cysteine peptidase 0.0068 0.0167 0.2424
Mycobacterium ulcerans fatty-acid-CoA ligase 0.0093 0.024 0.5878
Leishmania major cathepsin L-like protease 0.0068 0.0167 0.0158
Brugia malayi hypothetical protein 0.0016 0.0008 0.0003
Echinococcus multilocularis 7TM GPCR, rhodopsin 0.0022 0.0026 0.0021
Brugia malayi Nuclear hormone receptor family member nhr-31 0.0052 0.0117 0.0112
Schistosoma mansoni hypothetical protein 0.0039 0.0077 0.0072
Schistosoma mansoni kinase 0.0051 0.0116 0.0111
Echinococcus multilocularis rhodopsin orphan GPCR 0.0022 0.0026 0.0021
Echinococcus multilocularis nuclear receptor subfamily 4 group A 0.0025 0.0034 0.0029
Schistosoma mansoni jumonji/arid domain-containing protein 0.0099 0.026 0.0255
Brugia malayi cathepsin F-like cysteine proteinase 0.0023 0.0029 0.0024
Loa Loa (eye worm) hypothetical protein 0.0017 0.0013 0.0008
Onchocerca volvulus 0.0046 0.0099 0.0467
Plasmodium falciparum ataxin-2 like protein, putative 0.0024 0.0034 0.0055
Leishmania major cathepsin L-like protease 0.0068 0.0167 0.0158
Onchocerca volvulus 0.0022 0.0026 0.0068
Loa Loa (eye worm) TKL/STKR/TYPE2 protein kinase 0.0064 0.0155 0.015
Echinococcus granulosus lysine specific demethylase 5A 0.0099 0.026 0.0255
Loa Loa (eye worm) hypothetical protein 0.0022 0.0026 0.0021
Entamoeba histolytica cysteine protease, putative 0.0035 0.0067 0.0749
Echinococcus multilocularis insulin growth factor 1 receptor beta 0.0102 0.0269 0.0264
Loa Loa (eye worm) MH2 domain-containing protein 0.014 0.0382 0.0377
Brugia malayi Patched family protein 0.0017 0.0013 0.0008
Toxoplasma gondii histone lysine methyltransferase SET/SUV39 0.003 0.005 0.0089
Onchocerca volvulus 0.0052 0.0117 0.0567
Giardia lamblia Kinase, AGC PKA 0.0025 0.0035 0.1085
Echinococcus granulosus rhodopsin orphan GPCR 0.0022 0.0026 0.0021
Onchocerca volvulus 0.0025 0.0034 0.0116
Echinococcus multilocularis g protein coupled receptor 0.0022 0.0026 0.0021
Schistosoma mansoni subfamily S1A unassigned peptidase (S01 family) 0.0627 0.1851 0.1847
Schistosoma mansoni neuropeptide receptor 0.0022 0.0026 0.0021
Trichomonas vaginalis replication factor C large subunit, putative 0.0019 0.0018 0.0202
Loa Loa (eye worm) hypothetical protein 0.002 0.0021 0.0016
Brugia malayi hypothetical protein 0.0022 0.0026 0.0021
Schistosoma mansoni hypothetical protein 0.0046 0.0099 0.0094
Loa Loa (eye worm) neuropeptide F receptor 0.0022 0.0026 0.0021
Loa Loa (eye worm) hypothetical protein 0.0046 0.0099 0.0094
Brugia malayi glutathione reductase 0.0046 0.0099 0.0094
Brugia malayi Matrixin family protein 0.0106 0.028 0.0275
Schistosoma mansoni subfamily S1A unassigned peptidase (S01 family) 0.0627 0.1851 0.1847
Brugia malayi Patched family protein 0.0017 0.0013 0.0008
Echinococcus multilocularis nervana 2 0.002 0.0022 0.0017
Plasmodium falciparum cysteine proteinase falcipain 2b 0.0068 0.0167 0.0339
Schistosoma mansoni thyroid hormone receptor 0.0184 0.0517 0.0512
Echinococcus multilocularis tumor protein p63 0.1018 0.3032 0.3029

Activities

Activity type Activity value Assay description Source Reference
Ki (binding) = 0.21 nM Inhibition of [3H]-quinpirole binding to rat striatal membrane Dopamine receptor D2 without GTP and sodium ChEMBL. 10498215
Ki (binding) = 0.21 nM In vitro high binding affinity towards Dopamine receptor D2 by the displacement of [3H]-quinpirole radioligand in rat striatal membranes ChEMBL. 10354409
Ki (binding) = 0.21 nM Inhibition of [3H]-quinpirole binding to rat striatal membrane Dopamine receptor D2 without GTP and sodium ChEMBL. 10498215
Ki (binding) = 0.21 nM In vitro high binding affinity towards Dopamine receptor D2 by the displacement of [3H]-quinpirole radioligand in rat striatal membranes ChEMBL. 10354409
Ki (binding) = 2.8 nM Inhibition of [3H]-spiperone binding to human Dopamine receptor D3 in CHO cell membranes ChEMBL. 10498215
Ki (binding) = 2.8 nM Inhibition of [3H]-spiperone binding to human Dopamine receptor D3 in CHO cell membranes ChEMBL. 10498215
Ki (binding) = 4.25 nM Inihibition of [3H]-spiperone binding to human Dopamine receptor D2 in CHO cell membranes ChEMBL. 10498215
Ki (binding) = 4.25 nM Inihibition of [3H]-spiperone binding to human Dopamine receptor D2 in CHO cell membranes ChEMBL. 10498215
Ki (binding) = 10 nM Inhibition of [3H]-spiperone binding to human Dopamine receptor D4.4 expressed in CHO cell membranes ChEMBL. 10498215
Ki (binding) = 10 nM Inhibition of [3H]-spiperone binding to human Dopamine receptor D4.4 expressed in CHO cell membranes ChEMBL. 10498215
Ki (binding) = 11.4 nM Inhibtion of [3H]-spiperone binding to rat striatal membrane Dopamine receptor D2 low affinity without GTP and sodium ChEMBL. 10498215
Ki (binding) = 11.4 nM In vitro low binding affinity towards Dopamine receptor D2 by the displacement of [3H]-spiperone radioligand in rat striatal membranes ChEMBL. 10354409
Ki (binding) = 11.4 nM Inhibtion of [3H]-spiperone binding to rat striatal membrane Dopamine receptor D2 low affinity without GTP and sodium ChEMBL. 10498215
Ki (binding) = 11.4 nM In vitro low binding affinity towards Dopamine receptor D2 by the displacement of [3H]-spiperone radioligand in rat striatal membranes ChEMBL. 10354409
Ki (binding) = 306 nM In vitro binding affinity towards 5-hydroxytryptamine 1A receptor by the displacement of [3H]-8-OH-DPAT radioligand in rat hippocampal homogenates ChEMBL. 10354409
Ki (binding) = 306 nM In vitro binding affinity towards 5-hydroxytryptamine 1A receptor by the displacement of [3H]-8-OH-DPAT radioligand in rat hippocampal homogenates ChEMBL. 10354409
Ki (binding) = 1448 nM In vitro binding affinity towards Alpha-1 adrenergic receptor by the displacement of [3H]-prazosin radioligand in rat cortical homogenates ChEMBL. 10354409
Ki (binding) = 1448 nM In vitro binding affinity towards Alpha-1 adrenergic receptor by the displacement of [3H]-prazosin radioligand in rat cortical homogenates ChEMBL. 10354409
Ratio (binding) = 54 Relative binding affinity for low and hugh affinity type dopamine D2 receptors in rat striatal membranes ChEMBL. 10498215
Ratio (binding) = 54 Ratio of Dopamine D2 receptor (low)and Dopamine D2 receptor (high) ChEMBL. 10354409
Ratio (binding) = 54 Relative binding affinity for low and hugh affinity type dopamine D2 receptors in rat striatal membranes ChEMBL. 10498215
Ratio (binding) = 54 Ratio of Dopamine D2 receptor (low)and Dopamine D2 receptor (high) ChEMBL. 10354409

Phenotypes

Whole-cell/tissue/organism interactions

We have no records of whole-cell/tissue assays done with this compound What does this mean?

Many chemical entities in TDR Targets come from high-throughput screenings with whole cells or tissue samples, and not all assayed compounds have been tested against a single a single target protein, probably because they get ruled out during screening process. Even if these compounds may have not been of interest in the original screening, they may come as interesting leads for other screening assays. Furthermore, we may be able to propose drug-target associations using chemical similarities and network patterns.

Annotated phenotypes:

We have no manually annotated phenotypes for this drug. What does this mean? / Care to help?
In TDR Targets, information about phenotypes that are caused by drugs, or by genetic manipulation of cells (e.g. gene knockouts or knockdowns) is manually curated from the literature. These descriptions help to describe the potential of the target for drug development. If no information is available for this gene or if the information is incomplete, this may mean that i) the papers containing this information either appeared after the curation effort for this organism was carried out or they were inadvertently missed by curators; or that ii) the curation effort for this organism has not yet started.
 
In any case, if you have information about papers containing relevant validation data for this target, please log in using your TDR Targets username and password and send them to us using the corresponding form in this page (only visible to registered users) or contact us.

External resources for this compound

Bibliographic References

2 literature references were collected for this gene.

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