Detailed information for compound 1084119

Basic information

Technical information
  • Name: Unnamed compound
  • MW: 419.602 | Formula: C27H37N3O
  • H donors: 2 H acceptors: 2 LogP: 7.36 Rotable bonds: 10
    Rule of 5 violations (Lipinski): 1
  • SMILES: CCCCC1(CCCCC1)NC(=O)[C@@H](Nc1ccc(c2c1cccc2)C#N)CC(C)C
  • InChi: 1S/C27H37N3O/c1-4-5-15-27(16-9-6-10-17-27)30-26(31)25(18-20(2)3)29-24-14-13-21(19-28)22-11-7-8-12-23(22)24/h7-8,11-14,20,25,29H,4-6,9-10,15-18H2,1-3H3,(H,30,31)/t25-/m0/s1
  • InChiKey: KYJOLURRFAMUGC-VWLOTQADSA-N  


Substructure search Similarity search

Network

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Synonyms

No synonyms found for this compound

Targets

Known targets for this compound

No curated genes were found associated with this compound

Predicted pathogen targets for this compound

By orthology
No druggable targets predicted by orthology data
By sequence similarity to non orthologous known druggable targets
No druggable targets predicted by sequence similarity
Obtained from network model

Ranking Plot

Putative Targets List

Species Potential target Raw Global Species
Schistosoma mansoni apoptosis regulator bax 0.0086 0.0594 0.0592
Mycobacterium tuberculosis Probable isocitrate dehydrogenase [NADP] Icd1 (oxalosuccinate decarboxylase) (IDH) (NADP+-specific ICDH) (IDP) 0.0034 0.0184 0.0263
Loa Loa (eye worm) pip kinase 1 0.0014 0.0024 0.007
Chlamydia trachomatis acylglycerophosphoethanolamine acyltransferase 0.0073 0.049 0.3605
Schistosoma mansoni polycystin 1-related 0.0019 0.0067 0.0065
Echinococcus granulosus neuropeptide Y receptor 0.0012 0.0013 0.0012
Brugia malayi hypothetical protein 0.0012 0.0013 0.0036
Mycobacterium tuberculosis Conserved protein 0.0077 0.052 0.0748
Loa Loa (eye worm) GTP-binding regulatory protein alpha chain 0.0012 0.0013 0.0037
Mycobacterium tuberculosis Probable fatty-acid-CoA ligase FadD3 (fatty-acid-CoA synthetase) (fatty-acid-CoA synthase) 0.0069 0.0459 0.066
Loa Loa (eye worm) hypothetical protein 0.0141 0.1022 0.313
Loa Loa (eye worm) glutathione reductase 0.0098 0.0688 0.2104
Brugia malayi Pyridine nucleotide-disulphide oxidoreductase, dimerisation domain containing protein 0.0025 0.0114 0.0344
Loa Loa (eye worm) neuropeptide F receptor 0.0012 0.0013 0.0036
Schistosoma mansoni protein tyrosine phosphatase n11 (shp2) 0.0123 0.0883 0.0881
Mycobacterium tuberculosis NAD(P)H quinone reductase LpdA 0.0249 0.187 0.2694
Echinococcus granulosus aldehyde dehydrogenase mitochondrial 0.0061 0.0393 0.0392
Schistosoma mansoni opsin-like receptor 0.0012 0.0013 0.0012
Trypanosoma cruzi long-chain-fatty-acid-CoA ligase, putative 0.0029 0.0143 0.2072
Brugia malayi nuclear receptor NHR-88 0.002 0.0073 0.0221
Echinococcus multilocularis g-protein coupled receptor 0.0012 0.0013 0.0012
Mycobacterium tuberculosis Probable nitrite reductase [NAD(P)H] large subunit [FAD flavoprotein] NirB 0.0224 0.1674 0.2412
Echinococcus granulosus bromodomain adjacent to zinc finger domain 0.0065 0.0426 0.0424
Mycobacterium leprae PROBABLE ATP-DEPENDENT CLP PROTEASE PROTEOLYTIC SUBUNIT 1 CLPP1 (ENDOPEPTIDASE CLP) 0.0105 0.0738 0.1063
Schistosoma mansoni coup transcription factor 0.0042 0.0248 0.0246
Loa Loa (eye worm) hypothetical protein 0.0077 0.052 0.159
Brugia malayi isocitrate dehydrogenase 0.0034 0.0184 0.0559
Echinococcus granulosus neuropeptide Y receptor 0.0012 0.0013 0.0012
Loa Loa (eye worm) hypothetical protein 0.0012 0.0013 0.0036
Trypanosoma brucei hypothetical protein, conserved 0.0012 0.0015 0.0224
Onchocerca volvulus Steroid hormone receptor family member cnr14 homolog 0.0042 0.0248 0.0662
Plasmodium falciparum ADP-dependent DNA helicase RecQ 0.0042 0.0243 0.0348
Mycobacterium tuberculosis holo-[acyl-carrier protein] synthase AcpS (holo-ACP synthase) (CoA:APO-[ACP]pantetheinephosphotransferase) (CoA:APO-[acyl-carrie 0.0024 0.0107 0.0153
Loa Loa (eye worm) 5-hydroxytryptamine 2C receptor 0.0012 0.0013 0.0036
Loa Loa (eye worm) jmjC domain-containing protein 0.0066 0.0434 0.1326
Mycobacterium ulcerans pyruvate kinase 0.0033 0.0175 0.025
Loa Loa (eye worm) hypothetical protein 0.0054 0.0338 0.1031
Mycobacterium ulcerans DNA polymerase IV 0.004 0.0233 0.0334
Loa Loa (eye worm) hypothetical protein 0.0012 0.0013 0.0036
Trypanosoma cruzi DNA polymerase kappa, putative 0.004 0.0233 0.3379
Brugia malayi Dopamine receptor 0.0012 0.0013 0.0036
Plasmodium falciparum metacaspase-like protein 0.0028 0.0134 0.0192
Onchocerca volvulus 0.0063 0.0411 0.11
Echinococcus multilocularis phosphatidylinositol 5 phosphate 4 kinase type 2 0.0169 0.1244 0.1243
Plasmodium falciparum AP endonuclease (DNA-[apurinic or apyrimidinic site] lyase), putative 0.0037 0.021 0.03
Echinococcus multilocularis g protein coupled receptor 0.0012 0.0013 0.0012
Entamoeba histolytica phosphatidylinositol-4-phosphate 5-kinase, putative 0.0014 0.0024 0.0049
Brugia malayi Nuclear hormone receptor family member nhr-3 0.0042 0.0248 0.0755
Echinococcus multilocularis nuclear receptor subfamily 1 group D 0.0022 0.0092 0.0091
Schistosoma mansoni biogenic amine (5HT) receptor 0.0012 0.0013 0.0012
Loa Loa (eye worm) RecQ helicase 0.0047 0.0288 0.0878
Brugia malayi AMP-binding enzyme family protein 0.0029 0.0143 0.0433
Brugia malayi Inositol-1 0.0036 0.0197 0.06
Onchocerca volvulus Bile acid receptor homolog 0.0042 0.0248 0.0662
Echinococcus multilocularis ubiquitin specific protease 41 0.0075 0.0506 0.0505
Loa Loa (eye worm) hypothetical protein 0.002 0.0073 0.0221
Mycobacterium leprae Probable fatty-acid-CoA synthetase FadD22 (fatty-acid-CoA ligase) (fatty-acid-CoA synthase) 0.0029 0.0143 0.0204
Trichomonas vaginalis GTP-binding protein alpha subunit, gna, putative 0.0012 0.0013 0.0026
Echinococcus multilocularis tar DNA binding protein 0.0061 0.0397 0.0395
Wolbachia endosymbiont of Brugia malayi ATP-dependent Clp protease proteolytic subunit 0.016 0.117 1
Leishmania major hypothetical protein, conserved 0.0011 0.0001 0.0019
Trichomonas vaginalis conserved hypothetical protein 0.002 0.0078 0.0165
Echinococcus granulosus FTZ F1 nuclear receptor protein 0.0042 0.0248 0.0246
Brugia malayi intermediate filament protein 0.0055 0.0345 0.1055
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0012 0.0013 0.0012
Brugia malayi alpha keto acid dehydrogenase complex, E3 component, lipoamide dehydrogenase 0.0025 0.0114 0.0344
Mycobacterium tuberculosis Probable esterase LipL 0.0077 0.052 0.0748
Plasmodium falciparum acyl-CoA synthetase 0.0073 0.049 0.0705
Mycobacterium tuberculosis Peptide synthetase MbtE (peptide synthase) 0.0029 0.0143 0.0204
Toxoplasma gondii peptidylprolyl isomerase 0.0034 0.0182 0.1406
Loa Loa (eye worm) pre-SET domain-containing protein family protein 0.0427 0.3262 1
Brugia malayi Tachykinin-like peptides receptor 99D 0.0012 0.0013 0.0036
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0012 0.0013 0.0012
Schistosoma mansoni hypothetical protein 0.0012 0.0013 0.0012
Brugia malayi Nuclear hormone receptor family member nhr-25 0.0042 0.0248 0.0755
Brugia malayi AMP-binding enzyme family protein 0.0029 0.0143 0.0433
Trichomonas vaginalis conserved hypothetical protein 0.002 0.0078 0.0165
Echinococcus multilocularis Nuclear hormone receptor HR96 0.002 0.0073 0.0072
Loa Loa (eye worm) hypothetical protein 0.0169 0.1244 0.3812
Schistosoma mansoni cpg binding protein 0.0097 0.0681 0.068
Schistosoma mansoni rab6-interacting 0.0019 0.0067 0.0065
Loa Loa (eye worm) hypothetical protein 0.0012 0.0013 0.0036
Echinococcus multilocularis serotonin receptor 0.0012 0.0013 0.0012
Loa Loa (eye worm) heterotrimeric G protein alpha subunit 0.0012 0.0013 0.0037
Mycobacterium ulcerans acetyl-CoA synthetase 0.0029 0.0143 0.0204
Loa Loa (eye worm) G-protein-linked acetylcholine receptor protein 2 0.0012 0.0013 0.0036
Wolbachia endosymbiont of Brugia malayi dihydrolipoamide dehydrogenase E3 component 0.0034 0.0184 0.1577
Brugia malayi hypothetical protein 0.0012 0.0013 0.0036
Loa Loa (eye worm) steroid hormone receptor 0.0042 0.0248 0.0755
Schistosoma mansoni hypothetical protein 0.0012 0.0013 0.0012
Brugia malayi Nuclear hormone receptor-like 1 0.0042 0.0248 0.0755
Loa Loa (eye worm) hypothetical protein 0.0025 0.0116 0.0352
Trichomonas vaginalis GTP-binding protein alpha subunit, gna, putative 0.0012 0.0013 0.0026
Echinococcus granulosus ATP dependent DNA helicase Q5 0.002 0.007 0.0069
Brugia malayi nuclear receptor RXR 0.002 0.0073 0.0221
Toxoplasma gondii ATP-dependent DNA helicase, RecQ family protein 0.0032 0.0165 0.1274
Onchocerca volvulus 0.0012 0.0013 0.0031
Mycobacterium tuberculosis Probable oxidoreductase 0.0249 0.187 0.2694
Onchocerca volvulus 0.0055 0.0345 0.0925
Trypanosoma cruzi dihydrolipoamide dehydrogenase, putative 0.0034 0.0184 0.2678
Echinococcus multilocularis arachidonate 5 lipoxygenase 0.0053 0.0335 0.0334
Loa Loa (eye worm) hypothetical protein 0.0012 0.0013 0.0036
Loa Loa (eye worm) cytoplasmic intermediate filament protein 0.0029 0.0147 0.0446
Echinococcus multilocularis gtp binding protein (I) alpha 1subunit 0.0012 0.0013 0.0012
Echinococcus granulosus nuclear receptor 2DBD gamma 0.002 0.0073 0.0072
Trichomonas vaginalis inositol monophosphatase, putative 0.0036 0.0197 0.0421
Echinococcus multilocularis G-protein coupled receptor, putative 0.0012 0.0013 0.0012
Chlamydia trachomatis dihydrolipoyl dehydrogenase 0.0034 0.0184 0.0726
Trichomonas vaginalis phosphatidylinositol-4-phosphate 5-kinase type II, putative 0.0014 0.0024 0.0049
Mycobacterium tuberculosis Possible penicillin-binding protein 0.0492 0.3766 0.5428
Echinococcus granulosus methyl CpG binding domain protein 2 0.0017 0.0051 0.005
Loa Loa (eye worm) hypothetical protein 0.002 0.0073 0.0221
Loa Loa (eye worm) nuclear hormone receptor family member nhr-40 0.0042 0.0248 0.0755
Echinococcus multilocularis thioredoxin glutathione reductase 0.0098 0.0688 0.0686
Schistosoma mansoni biogenic amine receptor 0.0012 0.0013 0.0012
Loa Loa (eye worm) hypothetical protein 0.0073 0.049 0.15
Echinococcus multilocularis isocitrate dehydrogenase 2 (NADP+) 0.0034 0.0184 0.0182
Echinococcus granulosus snurportin 1 0.0308 0.2329 0.2328
Schistosoma mansoni ecdysone-induced protein 78c (dr-78) 0.0022 0.0092 0.0091
Echinococcus multilocularis zinc finger protein 0.0025 0.0111 0.011
Echinococcus granulosus GTP binding nuclear protein Ran 0.0021 0.0084 0.0083
Plasmodium falciparum thioredoxin reductase 0.0034 0.0184 0.0264
Mycobacterium tuberculosis Probable ATP-dependent CLP protease proteolytic subunit 2 ClpP2 (endopeptidase CLP 2) 0.0105 0.0738 0.1063
Echinococcus granulosus phosphatidylinositol 5 phosphate 4 kinase type 2 0.0169 0.1244 0.1243
Plasmodium falciparum ATP-dependent Clp protease proteolytic subunit 0.016 0.117 0.1685
Loa Loa (eye worm) hypothetical protein 0.002 0.0073 0.0221
Loa Loa (eye worm) hypothetical protein 0.0042 0.0248 0.0755
Trichomonas vaginalis GTP-binding protein alpha subunit, gna, putative 0.0012 0.0013 0.0026
Mycobacterium leprae conserved hypothetical protein 0.0077 0.052 0.0748
Brugia malayi putative neuropeptide receptor NPR1 0.0012 0.0013 0.0036
Brugia malayi nuclear receptor subfamily 1, group D, member 1, putative 0.002 0.0073 0.0221
Echinococcus granulosus nuclear receptor 2DBD gamma 0.0042 0.0248 0.0246
Echinococcus granulosus retinoic acid receptor rxr beta a 0.0042 0.0248 0.0246
Mycobacterium leprae Probable lipase LipE 0.0077 0.052 0.0748
Loa Loa (eye worm) nuclear receptor nhr-7B 0.002 0.0073 0.0221
Leishmania major dihydrolipoamide dehydrogenase, putative 0.0034 0.0184 0.2678
Echinococcus multilocularis snurportin 1 0.0308 0.2329 0.2328
Schistosoma mansoni hypothetical protein 0.0308 0.2329 0.2328
Echinococcus granulosus sex peptide receptor 0.0012 0.0013 0.0012
Loa Loa (eye worm) hypothetical protein 0.002 0.0073 0.0221
Brugia malayi AMP-binding enzyme family protein 0.0098 0.0684 0.2094
Echinococcus multilocularis cytoplasmic intermediate filament protein 0.0026 0.0124 0.0123
Loa Loa (eye worm) hypothetical protein 0.0042 0.0248 0.0755
Echinococcus granulosus importin subunit beta 1 0.0029 0.0143 0.0142
Trichomonas vaginalis Importin beta-1 subunit, putative 0.0023 0.0101 0.0214
Plasmodium vivax metacaspase 1, putative 0.0028 0.0134 0.0192
Trypanosoma cruzi cytidylyltransferase, putative 0.0011 0.0001 0.0019
Loa Loa (eye worm) pigment dispersing factor receptor c 0.0206 0.1533 0.4698
Echinococcus granulosus inositol monophosphatase 1 0.0036 0.0197 0.0196
Schistosoma mansoni serine/threonine protein kinase 0.0098 0.0689 0.0687
Brugia malayi 3-hydroxyacyl-CoA dehydrogenase type II 0.0056 0.0359 0.1098
Trypanosoma brucei apurinic/apyrimidinic endonuclease, putative 0.0037 0.021 0.3046
Echinococcus granulosus bromodomain adjacent to zinc finger domain 0.0036 0.0199 0.0198
Loa Loa (eye worm) hypothetical protein 0.0077 0.052 0.159
Loa Loa (eye worm) pyruvate kinase 0.0033 0.0175 0.0531
Schistosoma mansoni DNA polymerase eta 0.0067 0.0441 0.0439
Plasmodium falciparum pyruvate kinase 2 0.0017 0.0049 0.0069
Brugia malayi Pre-SET motif family protein 0.0427 0.3262 1
Leishmania major ubiquitin hydrolase, putative,cysteine peptidase, Clan CA, family C19, putative 0.0075 0.0506 0.7353
Toxoplasma gondii inositol(myo)-1(or 4)-monophosphatase 2, putative 0.0036 0.0197 0.1521
Brugia malayi Bromodomain containing protein 0.008 0.0545 0.1669
Leishmania major acetyl-CoA synthetase, putative 0.0029 0.0143 0.2072
Loa Loa (eye worm) hypothetical protein 0.0098 0.0684 0.2094
Loa Loa (eye worm) hypothetical protein 0.0012 0.0013 0.0036
Trypanosoma cruzi DNA damage repair protein, putative 0.0012 0.0015 0.0224
Loa Loa (eye worm) jmjC domain-containing protein 0.0016 0.004 0.012
Trypanosoma cruzi dihydrolipoamide dehydrogenase, putative 0.0034 0.0184 0.2678
Brugia malayi exodeoxyribonuclease III family protein 0.0037 0.021 0.0639
Mycobacterium ulcerans fatty-acid-CoA ligase 0.0098 0.0684 0.0984
Schistosoma mansoni histone-lysine n-methyltransferase setb1 0.008 0.0544 0.0543
Echinococcus multilocularis neuropeptide FF receptor 2 0.0012 0.0013 0.0012
Mycobacterium tuberculosis Dihydrolipoamide dehydrogenase LpdC (lipoamide reductase (NADH)) (lipoyl dehydrogenase) (dihydrolipoyl dehydrogenase) (diaphoras 0.0249 0.187 0.2694
Schistosoma mansoni lipoxygenase 0.0019 0.0067 0.0065
Onchocerca volvulus 0.0077 0.052 0.1394
Trichomonas vaginalis Clan CA, family C19, ubiquitin hydrolase-like cysteine peptidase 0.0075 0.0506 0.1087
Schistosoma mansoni trimeric G-protein alpha o subunit 0.0012 0.0013 0.0012
Echinococcus granulosus 7TM GPCR rhodopsin 0.0012 0.0013 0.0012
Trichomonas vaginalis Clan CD, family C14, metacaspase-like cysteine peptidase 0.0028 0.0134 0.0286
Trichomonas vaginalis conserved hypothetical protein 0.0075 0.0506 0.1087
Entamoeba histolytica Ran family GTPase 0.0021 0.0084 0.0178
Brugia malayi Apoptosis regulator proteins, Bcl-2 family protein 0.0086 0.0594 0.1816
Plasmodium vivax importin-beta 2, putative 0.0029 0.0143 0.0205
Toxoplasma gondii exonuclease III APE 0.0037 0.021 0.162
Mycobacterium tuberculosis Phenyloxazoline synthase MbtB (phenyloxazoline synthetase) 0.0029 0.0143 0.0204
Trichomonas vaginalis conserved hypothetical protein 0.0028 0.0134 0.0286
Echinococcus granulosus nuclear receptor nhr 48 0.002 0.0073 0.0072
Echinococcus multilocularis dna polymerase kappa 0.004 0.0233 0.0231
Loa Loa (eye worm) hypothetical protein 0.002 0.0073 0.0221
Echinococcus granulosus thioredoxin glutathione reductase 0.0098 0.0688 0.0686
Loa Loa (eye worm) intermediate filament tail domain-containing protein 0.0055 0.0345 0.1055
Plasmodium falciparum zinc finger protein, putative 0.0013 0.0016 0.0021
Trypanosoma cruzi phosphatidylinositol-4-phosphate 5-kinase, putative 0.0014 0.0024 0.035
Loa Loa (eye worm) GTP-binding regulatory protein Gs alpha-S chain 0.0285 0.2145 0.6575
Schistosoma mansoni nuclear receptor nhr-48 0.002 0.0073 0.0072
Toxoplasma gondii isocitrate dehydrogenase 0.0034 0.0184 0.1419
Leishmania major hypothetical protein, conserved 0.0077 0.052 0.755
Echinococcus granulosus arachidonate 5 lipoxygenase 0.0053 0.0335 0.0334
Brugia malayi jmjC domain containing protein 0.0066 0.0434 0.1326
Schistosoma mansoni ap endonuclease 0.0037 0.021 0.0208
Loa Loa (eye worm) hypothetical protein 0.0077 0.052 0.159
Schistosoma mansoni neuropeptide f receptor 76f 0.0012 0.0013 0.0012
Loa Loa (eye worm) hypothetical protein 0.0073 0.049 0.15
Loa Loa (eye worm) hypothetical protein 0.0077 0.052 0.159
Schistosoma mansoni neuropeptide receptor 0.0012 0.0013 0.0012
Mycobacterium ulcerans acyl-CoA synthetase 0.0098 0.0684 0.0984
Loa Loa (eye worm) hypothetical protein 0.0098 0.0684 0.2094
Trypanosoma cruzi GTP-binding nuclear protein rtb2, putative 0.0021 0.0084 0.1218
Brugia malayi hypothetical protein 0.0019 0.0067 0.0201
Brugia malayi Isocitrate dehydrogenase 0.0034 0.0184 0.0559
Leishmania major DNA polymerase eta, putative 0.0039 0.0223 0.3243
Brugia malayi Pin1-type peptidyl-prolyl cis-trans isomerase, BmPin1 0.0035 0.0189 0.0574
Entamoeba histolytica pyruvate kinase, putative 0.0023 0.0097 0.0205
Mycobacterium tuberculosis Conserved hypothetical protein 0.004 0.0233 0.0334
Mycobacterium tuberculosis Probable membrane NADH dehydrogenase NdhA 0.0224 0.1674 0.2412
Loa Loa (eye worm) G-protein coupled receptor 0.0012 0.0013 0.0036
Echinococcus multilocularis neuropeptides capa receptor 0.0012 0.0013 0.0012
Echinococcus multilocularis Nuclear hormone receptor family member nhr 41 0.0042 0.0248 0.0246
Echinococcus multilocularis neuropeptide receptor 0.0012 0.0013 0.0012
Brugia malayi nuclear receptor NHR-88 0.0042 0.0248 0.0755
Trichomonas vaginalis antibiotic synthetase, putative 0.0029 0.0143 0.0304
Schistosoma mansoni biogenic amine receptor 0.0012 0.0013 0.0012
Trichomonas vaginalis CAMK family protein kinase 0.0098 0.0689 0.1479
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0012 0.0013 0.0012
Loa Loa (eye worm) hypothetical protein 0.0016 0.004 0.012
Brugia malayi MH2 domain containing protein 0.0115 0.0821 0.2512
Trichomonas vaginalis Clan CD, family C14, metacaspase-like cysteine peptidase 0.0028 0.0134 0.0286
Trichomonas vaginalis conserved hypothetical protein 0.002 0.0078 0.0165
Echinococcus granulosus cytoplasmic intermediate filament protein 0.0026 0.0124 0.0123
Onchocerca volvulus 0.0033 0.0172 0.046
Loa Loa (eye worm) hypothetical protein 0.0042 0.0248 0.0755
Onchocerca volvulus Nuclear receptor subfamily 6 group A member 1 homolog 0.002 0.0073 0.0193
Treponema pallidum 4'-phosphopantetheinyl transferase 0.0024 0.0107 0.0153
Toxoplasma gondii BRCA1 C Terminus (BRCT) domain-containing protein 0.0012 0.0015 0.0119
Echinococcus multilocularis acetyl coenzyme A synthetase, cytoplasmic 0.0029 0.0143 0.0141
Mycobacterium ulcerans fusion of enoyl-CoA hydratase, EchA21 and lipase, LipE 0.0077 0.052 0.0748
Mycobacterium ulcerans acyl-CoA synthetase 0.0029 0.0143 0.0204
Toxoplasma gondii isocitrate dehydrogenase 0.0034 0.0184 0.1419
Brugia malayi Serotonin receptor 0.0012 0.0013 0.0036
Toxoplasma gondii ICE family protease (caspase) p20 domain-containing protein 0.0028 0.0134 0.1037
Brugia malayi hypothetical protein 0.0012 0.0013 0.0036
Loa Loa (eye worm) hypothetical protein 0.0012 0.0013 0.0036
Trichomonas vaginalis antibiotic synthetase, putative 0.0029 0.0143 0.0304
Schistosoma mansoni dihydrolipoamide dehydrogenase 0.0034 0.0184 0.0183
Schistosoma mansoni cpg binding protein 0.009 0.0626 0.0624
Trichomonas vaginalis Importin beta-1 subunit, putative 0.0023 0.0101 0.0214
Trypanosoma brucei DNA polymerase kappa, putative 0.004 0.0233 0.3379
Loa Loa (eye worm) hypothetical protein 0.0073 0.049 0.15
Plasmodium vivax ATP-dependent Clp protease proteolytic subunit, putative 0.0055 0.0349 0.0501
Echinococcus multilocularis Jumonji, AT rich interactive domain 1B 0.0023 0.0096 0.0094
Echinococcus granulosus caspase 0.0028 0.0134 0.0133
Brugia malayi G-protein coupled receptor 0.0012 0.0013 0.0036
Schistosoma mansoni inositol monophosphatase 0.0036 0.0197 0.0196
Trichomonas vaginalis conserved hypothetical protein 0.002 0.0078 0.0165
Trichomonas vaginalis DNA helicase recq1, putative 0.0047 0.0288 0.0616
Schistosoma mansoni lamin 0.0055 0.0345 0.0344
Echinococcus granulosus DNA apurinic or apyrimidinic site lyase 0.0037 0.021 0.0208
Leishmania major DNA damage repair protein, putative 0.0012 0.0015 0.0224
Echinococcus granulosus hypothetical protein 0.0012 0.0013 0.0012
Trichomonas vaginalis pyruvate kinase, putative 0.0033 0.0175 0.0373
Schistosoma mansoni phosphatidylinositol-4-phosphate-5-kinaseputativ e 0.0014 0.0024 0.0023
Schistosoma mansoni hypothetical protein 0.0012 0.0013 0.0012
Trichomonas vaginalis myo inositol monophosphatase, putative 0.0036 0.0197 0.0421
Echinococcus granulosus JmjC domain containing protein 4 0.0016 0.004 0.0039
Leishmania major phosphatidylinositol-4-phosphate 5-kinase-like protein 0.0014 0.0024 0.035
Echinococcus granulosus thyrotropin releasing hormone receptor 0.0012 0.0013 0.0012
Leishmania major dihydrolipoamide dehydrogenase, putative 0.0034 0.0184 0.2678
Trichomonas vaginalis Clan CD, family C14, metacaspase-like cysteine peptidase 0.0028 0.0134 0.0286
Trypanosoma cruzi ISWI complex protein 0.0015 0.0037 0.0544
Loa Loa (eye worm) hypothetical protein 0.0012 0.0013 0.0036
Trypanosoma cruzi DNA polymerase kappa, putative 0.004 0.0233 0.3379
Echinococcus multilocularis pyruvate kinase 0.0017 0.0049 0.0048
Loa Loa (eye worm) pyruvate kinase 0.0033 0.0175 0.0531
Giardia lamblia DINP protein human, muc B family 0.004 0.0233 0.3366
Plasmodium vivax acetyl-CoA synthetase, putative 0.0029 0.0143 0.0204
Schistosoma mansoni growth hormone secretagogue receptor 0.0012 0.0013 0.0012
Schistosoma mansoni zinc finger protein 0.0025 0.0111 0.011
Schistosoma mansoni mixed-lineage leukemia protein mll 0.0025 0.0111 0.011
Echinococcus multilocularis orexin receptor type 2 0.0012 0.0013 0.0012
Trypanosoma brucei isocitrate dehydrogenase, putative 0.0034 0.0184 0.2668
Trypanosoma brucei peptidyl-prolyl cis-trans isomerase/rotamase, putative 0.0034 0.0182 0.2645
Echinococcus multilocularis caspase 3, apoptosis cysteine peptidase 0.0028 0.0134 0.0133
Echinococcus multilocularis lysine specific demethylase 5A 0.0059 0.0378 0.0377
Echinococcus multilocularis somatostatin receptor 0.0012 0.0013 0.0012
Schistosoma mansoni protein phosphatase 2C 0.0016 0.004 0.0039
Loa Loa (eye worm) hypothetical protein 0.0012 0.0013 0.0036
Brugia malayi Nuclear hormone receptor family member nhr-25 0.0042 0.0248 0.0755
Loa Loa (eye worm) bromodomain containing protein 0.0018 0.0056 0.0168
Echinococcus granulosus guanine nucleotide binding protein Gs subunit 0.0285 0.2145 0.2144
Trypanosoma brucei JmjC domain, hydroxylase, putative 0.0016 0.004 0.0588
Loa Loa (eye worm) hypothetical protein 0.0016 0.004 0.012
Loa Loa (eye worm) hypothetical protein 0.0029 0.0143 0.0436
Mycobacterium ulcerans acyl-CoA synthetase 0.0098 0.0684 0.0984
Loa Loa (eye worm) hypothetical protein 0.0065 0.0429 0.1311
Echinococcus multilocularis beta LACTamase domain containing family member 0.0077 0.052 0.0519
Onchocerca volvulus 0.0012 0.0013 0.0031
Loa Loa (eye worm) GTP-binding nuclear protein RAN/TC4 0.0021 0.0084 0.0253
Loa Loa (eye worm) hypothetical protein 0.0026 0.0122 0.037
Schistosoma mansoni tar DNA-binding protein 0.0061 0.0397 0.0395
Entamoeba histolytica serine/threonine protein kinase, putative 0.0098 0.0689 0.1479
Schistosoma mansoni neuropeptide receptor 0.0012 0.0013 0.0012
Echinococcus granulosus rhodopsin orphan GPCR 0.0012 0.0013 0.0012
Trypanosoma cruzi pyruvate kinase 2, putative 0.0033 0.0175 0.2534
Echinococcus multilocularis ATP dependent DNA helicase Q1 0.002 0.007 0.0069
Brugia malayi hypothetical protein 0.002 0.0073 0.0221
Schistosoma mansoni microtubule-associated protein tau 0.0681 0.5252 0.5252
Echinococcus multilocularis neuropeptide receptor A26 0.0473 0.3617 0.3616
Schistosoma mansoni pyruvate kinase 0.0033 0.0175 0.0173
Onchocerca volvulus 0.0012 0.0013 0.0031
Echinococcus granulosus pyruvate kinase 0.0033 0.0175 0.0173
Schistosoma mansoni inositol monophosphatase 0.0036 0.0197 0.0196
Echinococcus granulosus fetal alzheimer antigen falz 0.0028 0.0135 0.0133
Trypanosoma cruzi GTP-binding nuclear protein rtb2, putative 0.0021 0.0084 0.1218
Echinococcus multilocularis phosphatidylinositol phosphate 5 kinase type III 0.0014 0.0024 0.0023
Loa Loa (eye worm) hypothetical protein 0.0012 0.0013 0.0036
Echinococcus multilocularis caspase 8 0.0028 0.0134 0.0133
Trichomonas vaginalis CAMK family protein kinase 0.0098 0.0689 0.1479
Echinococcus granulosus G protein coupled receptor 139 0.0012 0.0013 0.0012
Echinococcus multilocularis aldehyde dehydrogenase, mitochondrial 0.0061 0.0393 0.0392
Echinococcus multilocularis FTZ F1 alpha 0.0042 0.0248 0.0246
Plasmodium vivax ADP-dependent DNA helicase RecQ, putative 0.0032 0.0168 0.024
Schistosoma mansoni retinoic acid receptor RXR 0.0042 0.0248 0.0246
Loa Loa (eye worm) pyruvate kinase 0.0033 0.0175 0.0531
Toxoplasma gondii 4'-phosphopantetheinyl transferase superfamily protein 0.0024 0.0107 0.0828
Leishmania major 4-coumarate:coa ligase-like protein 0.0098 0.0684 0.9934
Loa Loa (eye worm) nuclear receptor NHR-67 0.002 0.0073 0.0221
Echinococcus granulosus dro:myosuppressin receptor 0.0012 0.0013 0.0012
Trypanosoma cruzi pyruvate kinase 2, putative 0.0033 0.0175 0.2534
Giardia lamblia Pyruvate kinase 0.0033 0.0175 0.252
Echinococcus granulosus nuclear receptor 2DBD gamma 0.0042 0.0248 0.0246
Echinococcus multilocularis ubiquitin carboxyl terminal hydrolase 8 0.0075 0.0506 0.0505
Loa Loa (eye worm) hypothetical protein 0.002 0.0073 0.0221
Schistosoma mansoni RAR-like nuclear receptor 0.0042 0.0248 0.0246
Echinococcus multilocularis dro:myosuppressin receptor 0.0012 0.0013 0.0012
Plasmodium falciparum acetyl-CoA synthetase, putative 0.0029 0.0143 0.0204
Echinococcus multilocularis inositol monophosphatase 1 0.0036 0.0197 0.0196
Loa Loa (eye worm) transcription factor SMAD2 0.0115 0.0821 0.2512
Echinococcus multilocularis neuropeptide receptor 0.0012 0.0013 0.0012
Mycobacterium leprae PROBABLE NICOTINATE-NUCLEOTIDE ADENYLYLTRANSFERASE NADD (DEAMIDO-NAD(+) PYROPHOSPHORYLASE) (DEAMIDO-NAD(+) DIPHOSPHORYLASE) (NIC 0.0897 0.6937 1
Entamoeba histolytica hypothetical protein 0.0013 0.0016 0.0032
Loa Loa (eye worm) hypothetical protein 0.0012 0.0013 0.0036
Echinococcus multilocularis allatostatin A receptor 0.0012 0.0013 0.0012
Loa Loa (eye worm) hypothetical protein 0.0012 0.0013 0.0037
Mycobacterium ulcerans 4'-phosphopantetheinyl transferase 0.0024 0.0107 0.0153
Schistosoma mansoni GTP-binding protein alpha subunit gna 0.0012 0.0013 0.0012
Echinococcus granulosus g protein linked acetylcholine receptor gar 2a 0.0012 0.0013 0.0012
Trypanosoma cruzi PAB1-binding protein , putative 0.0026 0.0122 0.1772
Loa Loa (eye worm) FYVE finger-containing phosphoinositide kinase 0.0014 0.0024 0.007
Trypanosoma cruzi dihydrolipoyl dehydrogenase, putative 0.0034 0.0184 0.2678
Trichomonas vaginalis chromodomain helicase DNA binding protein, putative 0.002 0.0078 0.0165
Mycobacterium ulcerans phenyloxazoline synthase MbtB 0.0029 0.0143 0.0204
Trypanosoma cruzi dihydrolipoamide dehydrogenase, putative 0.0034 0.0184 0.2678
Schistosoma mansoni family S12 unassigned peptidase (S12 family) 0.0077 0.052 0.0519
Echinococcus multilocularis Polycystic kidney disease protein 0.0019 0.0067 0.0065
Loa Loa (eye worm) hypothetical protein 0.0073 0.049 0.15
Giardia lamblia Pyruvate kinase 0.0017 0.0049 0.0701
Trypanosoma brucei importin beta-1 subunit, putative 0.0029 0.0143 0.2084
Trichomonas vaginalis chromodomain helicase DNA binding protein, putative 0.002 0.0078 0.0165
Trypanosoma cruzi metacaspase 5, putative 0.0028 0.0134 0.195
Loa Loa (eye worm) guanine nucleotide-binding protein alpha-12 subunit 0.0012 0.0013 0.0037
Schistosoma mansoni peptide (allatostatin)-like receptor 0.0012 0.0013 0.0012
Mycobacterium ulcerans acyl-CoA synthetase 0.0029 0.0143 0.0204
Loa Loa (eye worm) hypothetical protein 0.0028 0.0134 0.0408
Echinococcus granulosus beta LACTamase domain containing family member 0.0077 0.052 0.0519
Plasmodium vivax isocitrate dehydrogenase [NADP], mitochondrial, putative 0.0034 0.0184 0.0263
Schistosoma mansoni ran 0.0021 0.0084 0.0083
Echinococcus granulosus terminal deoxycytidyl transferase rev1 0.004 0.0233 0.0231
Mycobacterium tuberculosis NADPH-dependent mycothiol reductase Mtr 0.0098 0.0688 0.0989
Trypanosoma brucei Metacaspase-4 0.0028 0.0134 0.195
Brugia malayi Serotonin/octopamine receptor family protein 7 0.0012 0.0013 0.0036
Schistosoma mansoni caspase-7 (C14 family) 0.0028 0.0134 0.0133
Loa Loa (eye worm) hypothetical protein 0.0077 0.052 0.159
Trypanosoma cruzi DNA polymerase eta, putative 0.0039 0.0223 0.3243
Leishmania major protein kinase, putative,polo-like protein kinase, putative 0.0098 0.0689 1
Trypanosoma cruzi hypothetical protein, conserved 0.0077 0.052 0.755
Mycobacterium ulcerans exodeoxyribonuclease III protein XthA 0.0037 0.021 0.03
Schistosoma mansoni SET domain protein 0.0011 0.0006 0.0005
Brugia malayi oxidoreductase, short chain dehydrogenase/reductase family protein 0.0029 0.0143 0.0433
Echinococcus multilocularis pyruvate kinase 0.0017 0.0049 0.0048
Toxoplasma gondii ICE family protease (caspase) p20 domain-containing protein 0.0028 0.0134 0.1037
Schistosoma mansoni ran 0.0021 0.0084 0.0083
Trypanosoma cruzi isocitrate dehydrogenase, putative 0.0034 0.0184 0.2668
Echinococcus multilocularis thyrotropin releasing hormone receptor 0.0012 0.0013 0.0012
Brugia malayi ecdysteroid receptor 0.0042 0.0248 0.0755
Loa Loa (eye worm) hypothetical protein 0.0012 0.0013 0.0036
Schistosoma mansoni mixed-lineage leukemia protein mll 0.0194 0.1437 0.1436
Trypanosoma cruzi phosphatidylinositol 4-phosphate 5-kinase alpha, putative 0.0014 0.0024 0.035
Trypanosoma brucei DNA damage repair protein, putative 0.0012 0.0015 0.0224
Trypanosoma brucei DNA polymerase kappa, putative 0.004 0.0233 0.3379
Mycobacterium tuberculosis Conserved protein 0.0077 0.052 0.0748
Echinococcus multilocularis Ataxin 2, N terminal,domain containing protein 0.0012 0.0009 0.0008
Trypanosoma cruzi dihydrolipoamide dehydrogenase, putative 0.0034 0.0184 0.2678
Trypanosoma brucei hypothetical protein, conserved 0.0012 0.0015 0.0224
Onchocerca volvulus Huntingtin homolog 0.0123 0.0877 0.2354
Echinococcus granulosus RUN 0.0019 0.0067 0.0065
Echinococcus multilocularis peptidase Clp (S14 family) 0.0105 0.0738 0.0737
Brugia malayi nuclear hormone receptor family member odr-7 0.002 0.0073 0.0221
Mycobacterium ulcerans fatty-acid-CoA ligase 0.0073 0.049 0.0705
Trypanosoma cruzi long-chain-fatty-acid-CoA ligase, putative 0.0029 0.0143 0.2072
Loa Loa (eye worm) pip kinase 2 0.0169 0.1244 0.3812
Onchocerca volvulus 0.0012 0.0013 0.0031
Brugia malayi guanine nucleotide-binding protein alpha-7 subunit, putative 0.0012 0.0013 0.0037
Mycobacterium ulcerans lipase LipD 0.0077 0.052 0.0748
Echinococcus multilocularis caspase 2 0.0028 0.0134 0.0133
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0012 0.0013 0.0012
Schistosoma mansoni mixed-lineage leukemia protein mll 0.0015 0.0037 0.0035
Loa Loa (eye worm) hypothetical protein 0.0077 0.052 0.159
Loa Loa (eye worm) hypothetical protein 0.0048 0.0292 0.0892
Leishmania major aldehyde dehydrogenase, mitochondrial precursor 0.0061 0.0393 0.5711
Brugia malayi G-protein alpha subunit 0.0012 0.0013 0.0037
Toxoplasma gondii ATP-dependent DNA helicase, RecQ family protein 0.002 0.007 0.0544
Mycobacterium ulcerans short-chain type dehydrogenase/reductase 0.0056 0.0359 0.0516
Echinococcus multilocularis tm gpcr rhodopsin gpcr rhodopsin superfamily 0.0012 0.0013 0.0012
Loa Loa (eye worm) hypothetical protein 0.002 0.007 0.0212
Schistosoma mansoni GTP-binding protein (I) alpha-2 subunit gnai2 0.0012 0.0013 0.0012
Toxoplasma gondii GTP-binding nuclear protein ran/tc4 0.0021 0.0084 0.0648
Echinococcus multilocularis g protein coupled receptor 0.0012 0.0013 0.0012
Brugia malayi sulfakinin receptor protein 0.0012 0.0013 0.0036
Brugia malayi glutaminase DH11.1 0.0276 0.2081 0.6379
Loa Loa (eye worm) hypothetical protein 0.0123 0.0877 0.2686
Schistosoma mansoni myosin xvIII 0.0012 0.0013 0.0012
Mycobacterium tuberculosis Probable short-chain type dehydrogenase/reductase 0.0056 0.0359 0.0516
Toxoplasma gondii LsmAD domain-containing protein 0.0026 0.0122 0.0943
Schistosoma mansoni bcl-2 homologous antagonist/killer (bak) 0.0086 0.0594 0.0592
Echinococcus granulosus acetyl coenzyme A synthetase cytoplasmic 0.0029 0.0143 0.0141
Mycobacterium tuberculosis Bifunctional enzyme MbtA: salicyl-AMP ligase (SAL-AMP ligase) + salicyl-S-ArCP synthetase 0.0029 0.0143 0.0204
Loa Loa (eye worm) nuclear hormone receptor family member nhr-1 0.0042 0.0248 0.0755
Mycobacterium ulcerans acyl-CoA synthetase 0.0029 0.0143 0.0204
Plasmodium vivax nicotinate-nucleotide adenylyltransferase, putative 0.0897 0.6937 1
Schistosoma mansoni jumonji domain containing protein 0.0059 0.0378 0.0377
Giardia lamblia DNA damage repair protein 0.0012 0.0015 0.0205
Mycobacterium ulcerans long-chain-fatty-acid-CoA ligase 0.0098 0.0684 0.0984
Brugia malayi Nuclear hormone receptor family member nhr-49 0.0042 0.0248 0.0755
Schistosoma mansoni ubiquitously transcribed sex (X/Y) chromosome tetratricopeptide repeat protein-related 0.0016 0.004 0.0039
Loa Loa (eye worm) exodeoxyribonuclease III family protein 0.0037 0.021 0.0639
Echinococcus granulosus tm gpcr rhodopsin 0.0012 0.0013 0.0012
Onchocerca volvulus 0.0486 0.3722 1
Plasmodium vivax JmjC domain containing protein 0.0016 0.004 0.0056
Mycobacterium ulcerans long-chain-fatty-acid--CoA ligase 0.0098 0.0684 0.0984
Brugia malayi hypothetical protein 0.0026 0.0122 0.037
Trypanosoma brucei dihydrolipoamide dehydrogenase 0.0034 0.0184 0.2678
Trypanosoma cruzi peptidyl-prolyl cis-trans isomerase 0.0034 0.0182 0.2645
Echinococcus multilocularis rhodopsin orphan GPCR 0.0012 0.0013 0.0012
Plasmodium vivax ataxin-2 like protein, putative 0.0026 0.0122 0.0174
Loa Loa (eye worm) hypothetical protein 0.0029 0.0143 0.0433
Loa Loa (eye worm) hypothetical protein 0.008 0.0544 0.1665
Onchocerca volvulus Huntingtin homolog 0.0123 0.0877 0.2354
Leishmania major hypothetical protein, conserved 0.0015 0.0037 0.0544
Schistosoma mansoni jumonji/arid domain-containing protein 0.0066 0.0434 0.0432
Echinococcus multilocularis DNA (apurinic or apyrimidinic site) lyase 0.0037 0.021 0.0208
Echinococcus multilocularis serine:threonine protein kinase PLK1 0.0098 0.0689 0.0687
Trichomonas vaginalis G protein (olf) alpha subunit, gnal, putative 0.0012 0.0013 0.0026
Loa Loa (eye worm) hypothetical protein 0.0022 0.0092 0.0278
Onchocerca volvulus Pyruvate kinase homolog 0.0033 0.0175 0.0465
Schistosoma mansoni neuropeptide F-like receptor 0.0012 0.0013 0.0012
Mycobacterium ulcerans hypothetical protein 0.0077 0.052 0.0748
Echinococcus granulosus Bcl 2 ous antagonist:killer 0.0086 0.0594 0.0592
Mycobacterium leprae POSSIBLE O-SUCCINYLBENZOIC ACID--CoA LIGASE MENE (OSB-CoA SYNTHETASE) (O-SUCCINYLBENZOATE-CoA SYNTHASE) 0.0029 0.0143 0.0204
Schistosoma mansoni amine GPCR 0.0012 0.0013 0.0012
Trypanosoma brucei metacaspase MCA2 0.0028 0.0134 0.195
Brugia malayi hypothetical protein 0.0019 0.0067 0.0201
Echinococcus multilocularis rhodopsin orphan GPCR 0.0012 0.0013 0.0012
Treponema pallidum ATP-dependent Clp protease proteolytic subunit 0.0055 0.0349 0.0501
Echinococcus multilocularis methyl CpG binding domain protein 2 0.0017 0.0051 0.005
Plasmodium vivax acyl-CoA synthetase, putative 0.0073 0.049 0.0705
Mycobacterium ulcerans O-succinylbenzoic acid--CoA ligase 0.0029 0.0143 0.0204
Plasmodium falciparum glutathione reductase 0.0098 0.0688 0.0989
Mycobacterium leprae DIHYDROLIPOAMIDE DEHYDROGENASE LPD (LIPOAMIDE REDUCTASE (NADH)) (LIPOYL DEHYDROGENASE) (DIHYDROLIPOYL DEHYDROGENASE) (DIAPHORASE 0.0249 0.187 0.2694
Mycobacterium ulcerans acyl-CoA synthetase 0.0029 0.0143 0.0204
Brugia malayi Guanine nucleotide-binding protein alpha-12 subunit, putative 0.0012 0.0013 0.0037
Mycobacterium tuberculosis Probable pyruvate kinase PykA 0.0033 0.0175 0.025
Trypanosoma cruzi dihydrolipoamide dehydrogenase, putative 0.0034 0.0184 0.2678
Trichomonas vaginalis D-aminoacylase, putative 0.0077 0.052 0.1116
Echinococcus multilocularis fmrfamide receptor 0.0012 0.0013 0.0012
Loa Loa (eye worm) hypothetical protein 0.0067 0.0441 0.1347
Toxoplasma gondii NADPH-glutathione reductase 0.0034 0.0184 0.1424
Echinococcus granulosus GPCR family 2 0.0065 0.0429 0.0428
Echinococcus multilocularis pyruvate kinase 0.0033 0.0175 0.0173
Trypanosoma cruzi phosphatidylinositol (3,5) kinase, putative 0.0014 0.0024 0.035
Loa Loa (eye worm) hypothetical protein 0.0075 0.0506 0.1549
Loa Loa (eye worm) hypothetical protein 0.0041 0.0237 0.0722
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0012 0.0013 0.0012
Schistosoma mansoni rab geranylgeranyl transferase alpha subunit 0.004 0.0233 0.0231
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0012 0.0013 0.0012
Plasmodium vivax pyruvate kinase 2, putative 0.0017 0.0049 0.0069
Schistosoma mansoni histone-lysine n-methyltransferase setb1 0.008 0.0544 0.0543
Echinococcus granulosus neuropeptides capa receptor 0.0012 0.0013 0.0012
Schistosoma mansoni histone-lysine n-methyltransferase setb1 0.0063 0.0411 0.0409
Loa Loa (eye worm) oxidoreductase 0.0029 0.0143 0.0433
Schistosoma mansoni bromodomain containing protein 0.0068 0.0454 0.0452
Echinococcus multilocularis Peptidase C19, ubiquitin carboxyl terminal hydrolase 2 0.0075 0.0506 0.0505
Brugia malayi nuclear hormone receptor family member nhr-6 0.002 0.0073 0.0221
Leishmania major long-chain-fatty-acid-CoA ligase, putative 0.0029 0.0143 0.2072
Loa Loa (eye worm) hypothetical protein 0.002 0.0073 0.0221
Brugia malayi Ligand-binding domain of nuclear hormone receptor family protein 0.0042 0.0248 0.0755
Echinococcus granulosus bloom syndrome protein 0.0047 0.0288 0.0286
Echinococcus multilocularis lamin dm0 0.0055 0.0345 0.0344
Loa Loa (eye worm) beta-LACTamase domain containing family member 0.0077 0.052 0.159
Brugia malayi Nuclear hormone receptor-like 1 0.0022 0.0092 0.0278
Loa Loa (eye worm) hypothetical protein 0.016 0.117 0.3583
Echinococcus granulosus 7tm_1 domain containing protein 0.0012 0.0013 0.0012
Echinococcus granulosus biogenic amine 5HT receptor 0.0012 0.0013 0.0012
Giardia lamblia Endonuclease/Exonuclease/phosphatase 0.0037 0.021 0.3032
Trypanosoma cruzi polo-like protein kinase, putative 0.0098 0.0689 1
Echinococcus multilocularis g protein linked acetylcholine receptor gar 2a 0.0012 0.0013 0.0012
Loa Loa (eye worm) ATP-dependent DNA helicase 0.002 0.007 0.0212
Loa Loa (eye worm) hypothetical protein 0.0016 0.004 0.012
Schistosoma mansoni hypothetical protein 0.0065 0.0429 0.0428
Echinococcus multilocularis histone lysine methyltransferase setb histone lysine methyltransferase eggless 0.008 0.0544 0.0543
Loa Loa (eye worm) TAR-binding protein 0.0061 0.0397 0.1213
Brugia malayi AKH receptor 0.0012 0.0013 0.0036
Toxoplasma gondii histone lysine demethylase JMJD6a 0.0016 0.004 0.0313
Echinococcus granulosus geminin 0.0731 0.564 0.564
Brugia malayi CXXC zinc finger family protein 0.009 0.0626 0.1914
Trypanosoma cruzi ubiquitin carboxyl-terminal hydrolase, putative 0.0075 0.0506 0.7353
Loa Loa (eye worm) Pin1-type peptidyl-prolyl cis-trans isomerase 0.0035 0.0189 0.0574
Leishmania major pyruvate kinase 0.0033 0.0175 0.2534
Chlamydia trachomatis pyruvate kinase 0.0033 0.0175 0.0633
Mycobacterium tuberculosis Probable soluble pyridine nucleotide transhydrogenase SthA (STH) (NAD(P)(+) transhydrogenase [B-specific]) (nicotinamide nucleot 0.0034 0.0184 0.0264
Mycobacterium tuberculosis Fatty-acid-AMP ligase FadD30 (fatty-acid-AMP synthetase) (fatty-acid-AMP synthase) 0.0073 0.049 0.0705
Trichomonas vaginalis Clan CD, family C14, metacaspase-like cysteine peptidase 0.0028 0.0134 0.0286
Loa Loa (eye worm) hypothetical protein 0.0012 0.0013 0.0037
Loa Loa (eye worm) hypothetical protein 0.0022 0.0092 0.0278
Echinococcus multilocularis NADP dependent isocitrate dehydrogenase 0.0034 0.0184 0.0182
Loa Loa (eye worm) hypothetical protein 0.002 0.0073 0.0221
Trypanosoma brucei phosphopantetheine adenylyltransferase, putative 0.0011 0.0001 0.0019
Loa Loa (eye worm) hypothetical protein 0.0012 0.0013 0.0036
Trypanosoma cruzi dihydrolipoamide dehydrogenase, putative 0.0034 0.0184 0.2678
Echinococcus multilocularis guanine nucleotide binding protein subunit 0.0012 0.0013 0.0012
Echinococcus granulosus pyroglutamylated rfamide peptide receptor 0.0012 0.0013 0.0012
Trypanosoma cruzi JmjC domain, hydroxylase, putative 0.0016 0.004 0.0588
Echinococcus multilocularis nuclear receptor 2DBD gamma 0.0042 0.0248 0.0246
Plasmodium falciparum DNA repair protein REV1, putative 0.0012 0.0015 0.002
Mycobacterium ulcerans long-chain fatty-acid CoA ligase 0.0098 0.0684 0.0984
Echinococcus multilocularis guanine nucleotide binding protein subunit 0.0012 0.0013 0.0012
Loa Loa (eye worm) nuclear hormone receptor family member nhr-14 0.0042 0.0248 0.0755
Brugia malayi follicle stimulating hormone receptor 0.0012 0.0013 0.0036
Mycobacterium ulcerans ATP-dependent Clp protease proteolytic subunit 0.016 0.117 0.1685
Brugia malayi AMP-binding enzyme family protein 0.0029 0.0143 0.0433
Trypanosoma brucei pyruvate kinase 1 0.0033 0.0175 0.2534
Schistosoma mansoni hypothetical protein 0.0731 0.564 0.564
Trypanosoma brucei phosphatidylinositol (3,5) kinase, putative 0.0014 0.0024 0.035
Loa Loa (eye worm) hypothetical protein 0.0345 0.2616 0.8018
Echinococcus granulosus Peptidase C19 ubiquitin carboxyl terminal hydrolase 2 0.0075 0.0506 0.0505
Echinococcus multilocularis expressed protein 0.0012 0.0013 0.0012
Echinococcus granulosus serotonin receptor 0.0012 0.0013 0.0012
Echinococcus multilocularis peptide (allatostatin:somatostatin) 0.0012 0.0013 0.0012
Echinococcus granulosus expressed protein 0.0035 0.0189 0.0187
Onchocerca volvulus Protein ultraspiracle homolog 0.0042 0.0248 0.0662
Onchocerca volvulus Neuropeptide F receptor homolog 0.0012 0.0013 0.0031
Schistosoma mansoni ap endonuclease 0.0037 0.021 0.0208
Brugia malayi hypothetical protein 0.0012 0.0013 0.0036
Echinococcus granulosus growth hormone secretagogue receptor type 1 0.0012 0.0013 0.0012
Trypanosoma brucei unspecified product 0.0028 0.0135 0.1959
Brugia malayi dihydrolipoyl dehydrogenase, mitochondrial precursor, putative 0.0034 0.0184 0.0561
Trypanosoma brucei ISWI complex protein 0.0015 0.0037 0.0544
Loa Loa (eye worm) hypothetical protein 0.0033 0.0175 0.0531
Mycobacterium tuberculosis Fatty-acid-CoA synthetase FadD17 (fatty-acid-CoA synthase) (fatty-acid-CoA ligase) 0.0029 0.0143 0.0204
Echinococcus granulosus guanine nucleotide binding protein subunit 0.0012 0.0013 0.0012
Schistosoma mansoni phd/f-box containing protein 0.0016 0.004 0.0039
Entamoeba histolytica hypothetical protein 0.0023 0.0101 0.0214
Trypanosoma brucei DNA damage repair protein, putative 0.0012 0.0015 0.0224
Onchocerca volvulus 0.002 0.0073 0.0193
Loa Loa (eye worm) histone methyltransferase 0.003 0.0154 0.0469
Echinococcus multilocularis GTP binding nuclear protein Ran 0.0021 0.0084 0.0083
Entamoeba histolytica acyl-coA synthetase, putative 0.0098 0.0684 0.1469
Onchocerca volvulus 0.0055 0.0345 0.0925
Loa Loa (eye worm) hypothetical protein 0.0042 0.0248 0.0755
Echinococcus granulosus COUP TF:Svp nuclear hormone receptor 0.0042 0.0248 0.0246
Trichomonas vaginalis conserved hypothetical protein 0.002 0.0078 0.0165
Mycobacterium leprae PROBABLE FATTY-ACID-CoA LIGASE FADD7 (FATTY-ACID-CoA SYNTHETASE) (FATTY-ACID-CoA SYNTHASE) 0.0098 0.0684 0.0984
Mycobacterium tuberculosis Probable NADH dehydrogenase Ndh 0.0224 0.1674 0.2412
Schistosoma mansoni myst-related protein 0.0013 0.0016 0.0015
Schistosoma mansoni zinc finger protein 0.0015 0.0037 0.0036
Wolbachia endosymbiont of Brugia malayi fructose-1,6-bisphosphatase 0.0036 0.0197 0.1684
Trypanosoma cruzi trypanothione reductase, putative 0.0034 0.0184 0.2678
Schistosoma mansoni phosphatidylinositol-4-phosphate 5-kinase type II 0.0014 0.0024 0.0023
Echinococcus multilocularis musashi 0.0055 0.0345 0.0344
Loa Loa (eye worm) AMP-binding enzyme family protein 0.0029 0.0143 0.0433
Schistosoma mansoni lipoxygenase 0.0053 0.0335 0.0334
Echinococcus granulosus L aminoadipate semialdehyde 0.0086 0.0592 0.0591
Brugia malayi F/Y-rich N-terminus family protein 0.0032 0.0166 0.0506
Trypanosoma cruzi peptidyl-prolyl cis-trans isomerase 0.0034 0.0182 0.2645
Trypanosoma brucei DNA polymerase eta, putative 0.0067 0.0441 0.6398
Trichomonas vaginalis DNA helicase recq, putative 0.0025 0.0115 0.0245
Leishmania major phosphopantetheinyl transferase-like protein 0.0024 0.0107 0.1558
Plasmodium falciparum ATP-dependent DNA helicase Q1 0.002 0.007 0.01
Echinococcus multilocularis dna polymerase eta 0.0067 0.0441 0.0439
Plasmodium falciparum metacaspase 1 0.0028 0.0134 0.0192
Echinococcus granulosus caspase 3 apoptosis cysteine peptidase 0.0028 0.0134 0.0133
Entamoeba histolytica hypothetical protein 0.0024 0.0107 0.0228
Echinococcus granulosus g protein coupled receptor 0.0012 0.0013 0.0012
Plasmodium falciparum thioredoxin reductase 0.0098 0.0688 0.0989
Echinococcus multilocularis g protein coupled receptor 0.0012 0.0013 0.0012
Brugia malayi neuropeptide F receptor 0.0012 0.0013 0.0036
Plasmodium vivax DNA repair protein REV1, putative 0.0012 0.0015 0.002
Schistosoma mansoni muscarinic acetylcholine (GAR) receptor 0.0012 0.0013 0.0012
Loa Loa (eye worm) apoptosis regulator protein 0.0086 0.0594 0.1816
Trypanosoma brucei DNA polymerase kappa, putative 0.004 0.0233 0.3379
Plasmodium vivax GTP-binding nuclear protein RAN/TC4, putative 0.0021 0.0084 0.0119
Echinococcus granulosus zinc finger protein 0.0025 0.0111 0.011
Schistosoma mansoni ancient conserved domain protein 2 (cyclin m2) 0.0012 0.0013 0.0012
Loa Loa (eye worm) jmjC domain-containing protein 0.0016 0.004 0.012
Loa Loa (eye worm) TYRA-2 protein 0.0012 0.0013 0.0036
Echinococcus multilocularis pyruvate kinase 0.0017 0.0049 0.0048
Onchocerca volvulus 0.0086 0.0592 0.1587
Trypanosoma cruzi DNA polymerase kappa, putative 0.004 0.0233 0.3379
Echinococcus multilocularis COUP TF:Svp nuclear hormone receptor 0.0042 0.0248 0.0246
Trichomonas vaginalis mercuric reductase, putative 0.0034 0.0184 0.0394
Echinococcus granulosus ubiquitin carboxyl terminal hydrolase 8 0.0075 0.0506 0.0505
Onchocerca volvulus Cell death protein 3 homolog 0.0028 0.0134 0.0357
Mycobacterium leprae possible inositol monophosphatase SubH (IMPase) (inositol-1-phosphatase) (I-1-Pase ). 0.0032 0.0168 0.024
Trichomonas vaginalis importin beta-1, putative 0.0023 0.0101 0.0214
Mycobacterium ulcerans long-chain-acyl-CoA synthetase 0.0029 0.0143 0.0204
Echinococcus granulosus tar DNA binding protein 0.0061 0.0397 0.0395
Mycobacterium leprae PROBABLE NADH DEHYDROGENASE NDH 0.0224 0.1674 0.2412
Plasmodium vivax thioredoxin reductase, putative 0.0098 0.0688 0.0989
Trypanosoma cruzi metacaspase, putative 0.0028 0.0134 0.195
Plasmodium vivax hypothetical protein, conserved 0.0014 0.0024 0.0033
Brugia malayi ImpB/MucB/SamB family protein 0.0067 0.0441 0.1347
Toxoplasma gondii phosphatidylinositol-4-phosphate 5-Kinase 0.0014 0.0024 0.0186
Onchocerca volvulus Serine\/threonine kinase homolog 0.0098 0.0689 0.1847
Leishmania major DNA polymerase eta, putative 0.0067 0.0441 0.6398
Echinococcus granulosus Nuclear hormone receptor family member nhr 41 0.0042 0.0248 0.0246
Trypanosoma cruzi trypanothione reductase, putative 0.0098 0.0688 0.9984
Loa Loa (eye worm) jmjC domain-containing protein 0.0016 0.004 0.012
Trypanosoma cruzi hypothetical protein, conserved 0.0012 0.0015 0.0224
Schistosoma mansoni GTP-binding protein (I) alpha-2 subunit gnai2 0.0012 0.0013 0.0012
Trypanosoma cruzi DNA polymerase eta, putative 0.0067 0.0441 0.6398
Echinococcus granulosus dihydrolipoamide dehydrogenase 0.0034 0.0184 0.0183
Echinococcus granulosus neuropeptide receptor 0.0012 0.0013 0.0012
Trypanosoma brucei DNA polymerase IV, putative 0.004 0.0233 0.3379
Trichomonas vaginalis Clan CD, family C14, metacaspase-like cysteine peptidase 0.0028 0.0134 0.0286
Leishmania major pyruvate kinase 0.0033 0.0175 0.2534
Toxoplasma gondii ImpB/MucB/SamB family protein 0.0012 0.0015 0.0119
Onchocerca volvulus 0.0042 0.0248 0.0662
Mycobacterium tuberculosis Possible conserved lipoprotein LpqK 0.0077 0.052 0.0748
Echinococcus multilocularis rhodopsin orphan GPCR 0.0012 0.0013 0.0012
Mycobacterium tuberculosis Probable medium chain fatty-acid-CoA ligase FadD14 (fatty-acid-CoA synthetase) (fatty-acid-CoA synthase) 0.0029 0.0143 0.0204
Trypanosoma brucei nicotinamide/nicotinic acid mononucleotide adenylyltransferase 0.0011 0.0001 0.0019
Schistosoma mansoni aldehyde dehydrogenase 0.0061 0.0393 0.0392
Trypanosoma brucei DNA polymerase kappa, putative 0.0012 0.0015 0.0224
Onchocerca volvulus 0.0012 0.0013 0.0032
Brugia malayi GTP-binding nuclear protein RAN/TC4 0.0021 0.0084 0.0253
Schistosoma mansoni hypothetical protein 0.0065 0.0429 0.0428
Trypanosoma cruzi pantothenate kinase subunit, putative 0.0012 0.0008 0.0115
Echinococcus granulosus biogenic amine 5HT receptor 0.0012 0.0013 0.0012
Trichomonas vaginalis rotamase, putative 0.0034 0.0182 0.0389
Echinococcus multilocularis Transcription factor, JmjC domain containing protein 0.0059 0.0378 0.0377
Trypanosoma brucei trypanothione reductase 0.0098 0.0688 0.9984
Schistosoma mansoni pyruvate kinase 0.0033 0.0175 0.0173
Mycobacterium tuberculosis Probable chain -fatty-acid-CoA ligase FadD13 (fatty-acyl-CoA synthetase) 0.0098 0.0684 0.0984
Schistosoma mansoni glutaminase 0.0276 0.2081 0.208
Toxoplasma gondii Phosphoethanolamine-cytidyltransferase 0.0011 0.0001 0.001
Brugia malayi Steroid receptor seven-up type 2 0.0042 0.0248 0.0755
Loa Loa (eye worm) G protein alpha subunit 3 0.0012 0.0013 0.0037
Echinococcus multilocularis JmjC domain containing protein 4 0.0016 0.004 0.0039
Mycobacterium tuberculosis Putative ferredoxin reductase 0.0224 0.1674 0.2412
Mycobacterium ulcerans DNA polymerase IV 0.004 0.0233 0.0334
Trypanosoma brucei hypothetical protein, conserved 0.0077 0.052 0.755
Onchocerca volvulus 0.0169 0.1244 0.3341
Mycobacterium tuberculosis Probable fatty-acid-CoA ligase FadD7 (fatty-acid-CoA synthetase) (fatty-acid-CoA synthase) 0.0069 0.0459 0.066
Loa Loa (eye worm) hypothetical protein 0.0123 0.0877 0.2686
Echinococcus multilocularis G protein coupled receptor 139 0.0012 0.0013 0.0012
Onchocerca volvulus 0.0077 0.052 0.1394
Loa Loa (eye worm) hypothetical protein 0.0012 0.0013 0.0036
Trichomonas vaginalis conserved hypothetical protein 0.0028 0.0134 0.0286
Leishmania major isocitrate dehydrogenase [NADP], mitochondrial precursor, putative 0.0034 0.0184 0.2668
Brugia malayi hypothetical protein 0.0017 0.005 0.0148
Trypanosoma cruzi metacaspase, putative 0.0028 0.0134 0.195
Trypanosoma brucei metacaspase MCA3 0.0028 0.0134 0.195
Mycobacterium ulcerans glutaminase 0.0276 0.2081 0.2999
Onchocerca volvulus 0.0077 0.052 0.1394
Toxoplasma gondii ATP-dependent Clp endopeptidase, proteolytic subunit ClpP domain-containing protein 0.016 0.117 0.9034
Trichomonas vaginalis conserved hypothetical protein 0.0028 0.0134 0.0286
Onchocerca volvulus 0.0012 0.0013 0.0031
Loa Loa (eye worm) hypothetical protein 0.0012 0.0013 0.0036
Trichomonas vaginalis conserved hypothetical protein 0.0028 0.0134 0.0286
Schistosoma mansoni intermediate filament proteins 0.0055 0.0345 0.0344
Plasmodium vivax SET domain protein, putative 0.0063 0.0411 0.059
Echinococcus multilocularis biogenic amine (5HT) receptor 0.0012 0.0013 0.0012
Loa Loa (eye worm) unidentified vitellogenin-linked transcript protein 6 0.0012 0.0013 0.0036
Brugia malayi Pip kinase protein 2 0.0169 0.1244 0.3812
Entamoeba histolytica G protein alpha subunit, putative 0.0012 0.0013 0.0026
Treponema pallidum ATP-dependent Clp protease proteolytic subunit 0.016 0.117 0.1685
Echinococcus multilocularis tyrosine protein phosphatase non receptor type 0.0123 0.0883 0.0881
Entamoeba histolytica exodeoxyribonuclease III, putative 0.0037 0.021 0.0448
Treponema pallidum exodeoxyribonuclease (exoA) 0.0037 0.021 0.03
Brugia malayi hypothetical protein 0.0012 0.0013 0.0036
Loa Loa (eye worm) follicle stimulating hormone receptor 0.0012 0.0013 0.0036
Echinococcus granulosus pyruvate kinase 0.0017 0.0049 0.0048
Trichomonas vaginalis hypothetical protein 0.0011 0.0004 0.0005
Loa Loa (eye worm) MH2 domain-containing protein 0.0115 0.0821 0.2512
Trypanosoma cruzi importin beta-1 subunit, putative 0.0023 0.0101 0.1464
Trypanosoma brucei phosphatidylinositol-4-phosphate 5-kinase, putative 0.0014 0.0024 0.035
Trypanosoma brucei unspecified product 0.004 0.0233 0.3379
Mycobacterium tuberculosis Possible DNA-damage-inducible protein P DinP (DNA polymerase V) (pol IV 2) (DNA nucleotidyltransferase (DNA-directed)) 0.004 0.0233 0.0334
Onchocerca volvulus 0.0011 0.0006 0.0013
Schistosoma mansoni neuropeptide receptor 0.0012 0.0013 0.0012
Schistosoma mansoni aldehyde dehydrogenase 0.0061 0.0393 0.0392
Leishmania major myo-inositol-1(or 4)-monophosphatase 1, putative 0.0036 0.0197 0.286
Brugia malayi Calcitonin receptor-like protein seb-1 0.0206 0.1533 0.4698
Plasmodium falciparum ataxin-2 like protein, putative 0.0026 0.0122 0.0174
Brugia malayi Doublecortin family protein 0.0019 0.0067 0.0201
Trichomonas vaginalis conserved hypothetical protein 0.0011 0.0004 0.0005
Loa Loa (eye worm) hypothetical protein 0.0012 0.0013 0.0036
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0012 0.0013 0.0012
Brugia malayi jmjC domain containing protein 0.0016 0.004 0.012
Trichomonas vaginalis CAMK family protein kinase 0.0098 0.0689 0.1479
Trypanosoma brucei PAB1-binding protein , putative 0.0026 0.0122 0.1772
Mycobacterium tuberculosis Peptide synthetase MbtF (peptide synthase) 0.0029 0.0143 0.0204
Toxoplasma gondii HEAT repeat-containing protein 0.0029 0.0143 0.1108
Wolbachia endosymbiont of Brugia malayi dihydrolipoamide dehydrogenase E3 component 0.0034 0.0184 0.1577
Plasmodium vivax pyruvate kinase, putative 0.0033 0.0175 0.025
Brugia malayi ORL1-like opioid receptor 0.0012 0.0013 0.0036
Plasmodium vivax dihydrolipoyl dehydrogenase, mitochondrial, putative 0.0034 0.0184 0.0264
Schistosoma mansoni hypothetical protein 0.0019 0.0067 0.0065
Loa Loa (eye worm) hypothetical protein 0.0012 0.0013 0.0036
Brugia malayi hypothetical protein 0.0022 0.0092 0.0278
Mycobacterium leprae PROBABLE FATTY-ACID-CoA LIGASE FADD2 (FATTY-ACID-CoA SYNTHETASE) (FATTY-ACID-CoA SYNTHASE) 0.0098 0.0684 0.0984
Brugia malayi PHD-finger family protein 0.003 0.0153 0.0465
Onchocerca volvulus 0.0019 0.0067 0.0176
Trypanosoma cruzi acetyl-CoA synthetase, putative 0.0029 0.0143 0.2072
Brugia malayi Nuclear hormone receptor family member nhr-19 0.0042 0.0248 0.0755
Mycobacterium tuberculosis Probable dehydrogenase 0.0224 0.1674 0.2412
Echinococcus granulosus lysine specific demethylase 5A 0.0066 0.0434 0.0432
Brugia malayi RNA recognition motif domain containing protein 0.0061 0.0397 0.1213
Mycobacterium ulcerans beta-lactamase 0.0077 0.052 0.0748
Leishmania major hypothetical protein, conserved 0.0011 0.0001 0.0019
Trichomonas vaginalis GTP-binding protein (O) alpha subunit, gnao, putative 0.0012 0.0013 0.0026
Echinococcus granulosus neuropeptide s receptor 0.0473 0.3617 0.3616
Echinococcus granulosus cadherin EGF LAG seven pass G type receptor 0.0065 0.0429 0.0428
Echinococcus granulosus microtubule associated protein 2 0.0681 0.5252 0.5252
Loa Loa (eye worm) glutaminase 2 0.0276 0.2081 0.6379
Loa Loa (eye worm) hypothetical protein 0.0042 0.0248 0.0755
Trypanosoma brucei unspecified product 0.0028 0.0135 0.1959
Echinococcus granulosus orexin receptor type 2 0.0012 0.0013 0.0012
Mycobacterium ulcerans acyl-CoA synthetase 0.0029 0.0143 0.0204
Schistosoma mansoni peptide (FMRFamide/neurokinin-3)-like receptor 0.0012 0.0013 0.0012
Loa Loa (eye worm) hypothetical protein 0.0012 0.0013 0.0036
Giardia lamblia Hypothetical protein 0.0014 0.0024 0.0332
Mycobacterium tuberculosis Inositol-1-monophosphatase SuhB 0.0032 0.0168 0.024
Trichomonas vaginalis D-aminoacylase, putative 0.0077 0.052 0.1116
Loa Loa (eye worm) ImpB/MucB/SamB family protein 0.004 0.0233 0.0709
Echinococcus multilocularis pyruvate kinase 0.0026 0.012 0.0119
Schistosoma mansoni phosphatidylinositol-4-phosphate 5-kinase type II 0.0014 0.0024 0.0023
Echinococcus granulosus 5'partial|histone lysine N methyltransferase SETDB2 0.0059 0.0378 0.0376
Trichomonas vaginalis CAMK family protein kinase 0.0098 0.0689 0.1479
Trypanosoma brucei pyruvate kinase 1, putative 0.0033 0.0175 0.2534
Echinococcus granulosus dna polymerase eta 0.0067 0.0441 0.0439
Chlamydia trachomatis ATP-dependent Clp protease proteolytic subunit 0.016 0.117 1
Loa Loa (eye worm) neuropeptide F receptor 0.0012 0.0013 0.0036
Loa Loa (eye worm) hypothetical protein 0.0012 0.0013 0.0036
Onchocerca volvulus 0.009 0.0626 0.1678
Trypanosoma brucei ubiquitin carboxyl-terminal hydrolase, putative 0.0075 0.0506 0.7353
Trypanosoma cruzi phosphatidylinositol-4-phosphate 5-kinase type II beta, putative 0.0014 0.0024 0.035
Brugia malayi Nuclear hormone receptor E75 0.002 0.0073 0.0221
Schistosoma mansoni hepatocyte nuclear factor 4-alpha (hnf-4-alpha) 0.002 0.0073 0.0072
Entamoeba histolytica dual specificity protein phosphatase, putative 0.0604 0.4649 1
Loa Loa (eye worm) hypothetical protein 0.002 0.0073 0.0221
Brugia malayi Intermediate filament tail domain containing protein 0.0055 0.0345 0.1055
Onchocerca volvulus 0.002 0.0073 0.0193
Trypanosoma cruzi phosphatidylinositol-4-phosphate 5-kinase-like, putative 0.0014 0.0024 0.035
Echinococcus multilocularis GPCR, family 2 0.0065 0.0429 0.0428
Schistosoma mansoni nuclear receptor 0.002 0.0073 0.0072
Trichomonas vaginalis D-aminoacylase, putative 0.0077 0.052 0.1116
Schistosoma mansoni loxhd1 0.0019 0.0067 0.0065
Trichomonas vaginalis CAMK family protein kinase 0.0049 0.0299 0.0641
Brugia malayi neuropeptide F receptor 0.0012 0.0013 0.0036
Schistosoma mansoni nuclear hormone receptor superfamily protein-related 0.002 0.0073 0.0072
Schistosoma mansoni retinoid-x-receptor (RXR) 0.0022 0.0092 0.0091
Schistosoma mansoni opsin-like receptor 0.0012 0.0013 0.0012
Trichomonas vaginalis conserved hypothetical protein 0.0035 0.0189 0.0403
Mycobacterium tuberculosis Probable lipase LipE 0.0077 0.052 0.0748
Mycobacterium ulcerans long-chain-fatty-acid--CoA ligase 0.0029 0.0143 0.0204
Loa Loa (eye worm) hypothetical protein 0.002 0.0073 0.0221
Brugia malayi hypothetical protein 0.0012 0.0013 0.0036
Loa Loa (eye worm) gonadotropin-releasing hormone receptor 2 0.0012 0.0013 0.0036
Trypanosoma brucei cholinephosphate cytidylyltransferase A, putative 0.0011 0.0001 0.0019
Brugia malayi Cell death protein 3 precursor 0.0028 0.0134 0.0408
Echinococcus granulosus rhodopsin orphan GPCR 0.0012 0.0013 0.0012
Trichomonas vaginalis Clan CA, family C19, ubiquitin hydrolase-like cysteine peptidase 0.0075 0.0506 0.1087
Loa Loa (eye worm) hypothetical protein 0.0144 0.1043 0.3194
Schistosoma mansoni GTP-binding protein (I) alpha-1subunit gnai1 0.0012 0.0013 0.0012
Echinococcus granulosus histone lysine N methyltransferase MLL3 0.0025 0.0111 0.011
Trypanosoma cruzi hypothetical protein, conserved 0.0011 0.0001 0.0019
Chlamydia trachomatis ATP-dependent Clp protease proteolytic subunit 0.016 0.117 1
Onchocerca volvulus 0.0012 0.0013 0.0031
Entamoeba histolytica phosphoinositide kinase, putative 0.0014 0.0024 0.0049
Loa Loa (eye worm) hypothetical protein 0.0019 0.0067 0.0201
Echinococcus multilocularis ATP dependent Clp protease proteolytic subunit 0.016 0.117 0.1169
Schistosoma mansoni alpha-1 adrenergic receptor 0.0012 0.0013 0.0012
Mycobacterium leprae Probable pyruvate kinase PykA 0.0033 0.0175 0.025
Onchocerca volvulus 0.0029 0.0143 0.038
Trichomonas vaginalis esterase, putative 0.0077 0.052 0.1116
Brugia malayi ATP-dependent DNA helicase, RecQ family protein 0.002 0.007 0.0212
Trichomonas vaginalis Clan CD, family C14, metacaspase-like cysteine peptidase 0.0028 0.0134 0.0286
Schistosoma mansoni ubiquitin-specific peptidase 8 (C19 family) 0.0075 0.0506 0.0505
Loa Loa (eye worm) nuclear hormone receptor 0.002 0.0073 0.0221
Schistosoma mansoni hypothetical protein 0.0012 0.0013 0.0012
Loa Loa (eye worm) hypothetical protein 0.0012 0.0013 0.0036
Trypanosoma cruzi phosphatidylinositol-4-phosphate 5-kinase-like, putative 0.0014 0.0024 0.035
Trichomonas vaginalis chromodomain helicase DNA binding protein, putative 0.002 0.0078 0.0165
Brugia malayi Hypothetical 52.5 kDa protein ZK945.1 in chromosome II, putative 0.0077 0.052 0.159
Echinococcus multilocularis ATP dependent DNA helicase Q5 0.002 0.007 0.0069
Echinococcus granulosus tachykinin peptides receptor 99D 0.0012 0.0013 0.0012
Brugia malayi Nuclear hormone receptor family member nhr-41 0.0042 0.0248 0.0755
Trypanosoma cruzi hypothetical protein, conserved 0.0011 0.0001 0.0019
Brugia malayi jmjC domain containing protein 0.0016 0.004 0.012
Schistosoma mansoni cpg binding protein 0.0097 0.0681 0.068
Giardia lamblia Kinase, PLK 0.0098 0.0689 1
Trypanosoma cruzi dihydrolipoyl dehydrogenase, putative 0.0034 0.0184 0.2678
Loa Loa (eye worm) nucleolar RNA-associated protein alpha 0.0308 0.2329 0.7138
Mycobacterium ulcerans peptide synthetase Nrp (peptide synthase) 0.0029 0.0143 0.0204
Echinococcus granulosus ATP dependent Clp protease proteolytic subunit 0.016 0.117 0.1169
Brugia malayi TAR-binding protein 0.0061 0.0397 0.1213
Mycobacterium tuberculosis Probable hydrolase 0.0077 0.052 0.0748
Plasmodium falciparum dihydrolipoyl dehydrogenase, mitochondrial 0.0034 0.0184 0.0264
Schistosoma mansoni thyrotropin-releasing hormone receptor 0.0012 0.0013 0.0012
Echinococcus granulosus g protein coupled receptor 0.0012 0.0013 0.0012
Mycobacterium tuberculosis Probable conserved lipoprotein 0.0077 0.052 0.0748
Wolbachia endosymbiont of Brugia malayi 4'-phosphopantetheinyl transferase 0.0024 0.0107 0.0917
Toxoplasma gondii histone lysine methyltransferase SET1 0.0176 0.1295 1
Schistosoma mansoni hypothetical protein 0.0012 0.0009 0.0008
Mycobacterium tuberculosis PROBABLE FATTY-ACID-CoA LIGASE FADD18 (FRAGMENT) (FATTY-ACID-CoA SYNTHETASE) (FATTY-ACID-CoA SYNTHASE) 0.0025 0.0111 0.0159
Leishmania major phosphatidylinositol-4-phosphate 5-kinase-like, putative 0.0014 0.0024 0.035
Trypanosoma brucei long-chain-fatty-acid-CoA ligase, putative 0.0029 0.0143 0.2072
Brugia malayi Guanine nucleotide-binding protein alpha-3 subunit, putative 0.0012 0.0013 0.0037
Trichomonas vaginalis CAMK family protein kinase 0.0049 0.0299 0.0641
Brugia malayi RNA, U transporter 1 0.0082 0.056 0.1713
Schistosoma mansoni amine GPCR 0.0012 0.0013 0.0012
Brugia malayi serine/threonine-protein kinase plk-2 0.0098 0.0689 0.2108
Echinococcus multilocularis microtubule associated protein 2 0.0681 0.5252 0.5252
Trypanosoma brucei ethanolamine-phosphate cytidylyltransferase 0.0011 0.0001 0.0019
Schistosoma mansoni Tr4/Tr2 (homologue) 0.0042 0.0248 0.0246
Schistosoma mansoni tar DNA-binding protein 0.0061 0.0397 0.0395
Echinococcus multilocularis FTZ F1 nuclear receptor protein 0.0042 0.0248 0.0246
Giardia lamblia Sgs1 DNA helicase, putative 0.002 0.007 0.1005
Schistosoma mansoni GTP-binding protein (q) alpha-11 subunit gna11 0.0012 0.0013 0.0012
Brugia malayi Nuclear hormone receptor E75 0.002 0.0073 0.0221
Schistosoma mansoni nuclear hormone receptor 0.0042 0.0248 0.0246
Echinococcus multilocularis lamin 0.0055 0.0345 0.0344
Mycobacterium ulcerans acyl-CoA synthetase 0.0029 0.0143 0.0204
Echinococcus granulosus neuropeptide receptor 0.0012 0.0013 0.0012
Schistosoma mansoni DNA polymerase IV / kappa 0.0012 0.0015 0.0014
Loa Loa (eye worm) guanine nucleotide-binding protein alpha-6 subunit 0.0012 0.0013 0.0037
Mycobacterium ulcerans dihydrolipoamide dehydrogenase 0.0034 0.0184 0.0264
Schistosoma mansoni family S12 unassigned peptidase (S12 family) 0.0077 0.052 0.0519
Trypanosoma brucei DNA polymerase kappa, putative 0.0028 0.0135 0.1959
Echinococcus multilocularis terminal deoxycytidyl transferase rev1 0.004 0.0233 0.0231
Trypanosoma cruzi isocitrate dehydrogenase [NADP], mitochondrial precursor, putative 0.0034 0.0184 0.2668
Schistosoma mansoni hypothetical protein 0.1288 1 1
Echinococcus granulosus Nuclear hormone receptor HR96 0.002 0.0073 0.0072
Echinococcus granulosus Ataxin 2 N terminaldomain containing protein 0.0012 0.0009 0.0008
Mycobacterium tuberculosis Possible fatty-acid-CoA ligase FadD10 (fatty-acid-CoA synthetase) (fatty-acid-CoA synthase) 0.0029 0.0143 0.0204
Trichomonas vaginalis penicillin-binding protein, putative 0.0077 0.052 0.1116
Plasmodium falciparum ATP-dependent Clp protease proteolytic subunit 0.0055 0.0349 0.0501
Echinococcus multilocularis thyroid hormone receptor alpha 0.0042 0.0248 0.0246
Loa Loa (eye worm) hypothetical protein 0.0012 0.0013 0.0036
Brugia malayi beta-lactamase family protein 0.0077 0.052 0.159
Brugia malayi G protein-coupled receptor 0.0012 0.0013 0.0036
Mycobacterium tuberculosis Possible fatty-acid-CoA ligase FadD1 (fatty-acid-CoA synthetase) (fatty-acid-CoA synthase) 0.0029 0.0143 0.0204
Trypanosoma cruzi metacaspase, putative 0.0028 0.0134 0.195
Trypanosoma brucei phosphatidylinositol phosphate kinase alpha 0.0014 0.0024 0.035
Echinococcus granulosus nuclear receptor subfamily 1 group D 0.0022 0.0092 0.0091
Trypanosoma cruzi cholinephosphate cytidylyltransferase A, putative 0.0011 0.0001 0.0019
Echinococcus multilocularis hepatocyte nuclear factor 4 alpha 0.0042 0.0248 0.0246
Trypanosoma brucei DNA polymerase IV, putative 0.004 0.0233 0.3379
Brugia malayi RE15519p 0.0012 0.0013 0.0036
Loa Loa (eye worm) nuclear hormone receptor family member nhr-49 0.0042 0.0248 0.0755
Trypanosoma brucei phosphatidylinositol-4-phosphate 5-kinase, putative 0.0014 0.0024 0.035
Toxoplasma gondii ATP-dependent DNA helicase, RecQ family protein 0.002 0.007 0.0544
Loa Loa (eye worm) hypothetical protein 0.0071 0.0472 0.1442
Loa Loa (eye worm) hypothetical protein 0.0012 0.0013 0.0036
Schistosoma mansoni GTP-binding protein alpha subunit gna 0.0012 0.0013 0.0012
Schistosoma mansoni GTP-binding protein (q) alpha-11 subunit gna11 0.0012 0.0013 0.0012
Plasmodium vivax holo-[acyl-carrier-protein] synthase, putative 0.0024 0.0107 0.0153
Trichomonas vaginalis Clan CD, family C14, metacaspase-like cysteine peptidase 0.0028 0.0134 0.0286
Loa Loa (eye worm) hypothetical protein 0.0012 0.0013 0.0036
Mycobacterium leprae conserved hypothetical protein 0.0024 0.0107 0.0153
Schistosoma mansoni peptidase Clp (S14 family) 0.016 0.117 0.1169
Trichomonas vaginalis conserved hypothetical protein 0.002 0.0078 0.0165
Trichomonas vaginalis conserved hypothetical protein 0.002 0.0078 0.0165
Trypanosoma brucei isocitrate dehydrogenase [NADP], mitochondrial precursor, putative 0.0034 0.0184 0.2668
Mycobacterium ulcerans esterase/lipase LipP 0.0077 0.052 0.0748
Mycobacterium ulcerans aldehyde dehydrogenase 0.0061 0.0393 0.0565
Echinococcus multilocularis EGFP:Bcl2 fusion protein 0.0086 0.0594 0.0592
Schistosoma mansoni hypothetical protein 0.0065 0.0429 0.0428
Loa Loa (eye worm) latrophilin receptor protein 2 0.0065 0.0429 0.1311
Trypanosoma cruzi hypothetical protein, conserved 0.0012 0.0015 0.0224
Echinococcus multilocularis rhodopsin orphan GPCR 0.0012 0.0013 0.0012
Brugia malayi G-protein coupled receptor 0.0012 0.0013 0.0036
Schistosoma mansoni myst-related protein 0.0013 0.0016 0.0015
Onchocerca volvulus Pyruvate kinase homolog 0.0033 0.0175 0.0465
Onchocerca volvulus Dopamine\/Ecdysteroid receptor homolog 0.0012 0.0013 0.0031
Loa Loa (eye worm) doublecortin family protein 0.0019 0.0067 0.0201
Loa Loa (eye worm) hypothetical protein 0.0012 0.0013 0.0036
Loa Loa (eye worm) hypothetical protein 0.002 0.0073 0.0221
Brugia malayi Dopamine receptor protein 1, putative (partial) 0.0012 0.0013 0.0036
Echinococcus multilocularis nuclear receptor subfamily 4 group A 0.002 0.0073 0.0072
Echinococcus multilocularis dnaJ subfamily B 0.1288 1 1
Mycobacterium tuberculosis Probable fatty-acid-CoA ligase FadD35 (fatty-acid-CoA synthetase) (fatty-acid-CoA synthase) 0.0069 0.0459 0.066
Leishmania major 4-coumarate:coa ligase-like protein 0.0098 0.0684 0.9934
Echinococcus multilocularis fmrfamide receptor 0.0012 0.0013 0.0012
Brugia malayi ImpB/MucB/SamB family protein 0.004 0.0233 0.0709
Loa Loa (eye worm) DR-78 0.002 0.0073 0.0221
Brugia malayi Nuclear hormone receptor family member nhr-1 0.0042 0.0248 0.0755
Loa Loa (eye worm) hypothetical protein 0.0042 0.0248 0.0755
Brugia malayi beta-lactamase family protein 0.0077 0.052 0.159
Loa Loa (eye worm) hypothetical protein 0.0029 0.0143 0.0433
Echinococcus multilocularis rhodopsin orphan GPCR 0.0012 0.0013 0.0012
Trypanosoma brucei hypothetical protein, conserved 0.0024 0.0107 0.1558
Brugia malayi guanine nucleotide-binding protein G-o protein alpha subunit 0.0012 0.0013 0.0037
Brugia malayi Melatonin receptor type 1A 0.0012 0.0013 0.0036
Plasmodium falciparum GTP-binding nuclear protein RAN/TC4 0.0021 0.0084 0.0119
Schistosoma mansoni neuropeptide receptor 0.0012 0.0013 0.0012
Echinococcus granulosus cpg binding protein 0.0097 0.0681 0.068
Trypanosoma cruzi cholinephosphate cytidylyltransferase A, putative 0.0011 0.0001 0.0019
Leishmania major ethanolamine-phosphate cytidylyltransferase, putative 0.0011 0.0001 0.0019
Trypanosoma brucei chrX additional, unordered contigs 0.0012 0.0015 0.0224
Echinococcus granulosus gtp binding protein I alpha 1subunit 0.0012 0.0013 0.0012
Onchocerca volvulus 0.0012 0.0013 0.0031
Brugia malayi Nuclear hormone receptor family member nhr-14 0.0042 0.0248 0.0755
Echinococcus multilocularis caspase 0.0028 0.0134 0.0133
Echinococcus granulosus ecdysone induced protein 78C 0.0042 0.0248 0.0246
Trichomonas vaginalis conserved hypothetical protein 0.002 0.0078 0.0165
Schistosoma mansoni hypothetical protein 0.0731 0.564 0.564
Mycobacterium ulcerans non-ribosomal peptide synthetase MbtF 0.0029 0.0143 0.0204
Trypanosoma brucei polo-like protein kinase 0.0098 0.0689 1
Loa Loa (eye worm) hypothetical protein 0.0086 0.0594 0.1816
Trypanosoma brucei DNA polymerase kappa, putative 0.004 0.0233 0.3379
Leishmania major 3-oxoacyl-(acyl-carrier protein) reductase, putative 0.0056 0.0359 0.5219
Echinococcus granulosus EGFP:Bcl2 fusion protein 0.0086 0.0594 0.0592
Echinococcus granulosus pyruvate kinase 0.0017 0.0049 0.0048
Echinococcus multilocularis bloom syndrome protein 0.0047 0.0288 0.0286
Mycobacterium ulcerans bifunctional nicotinate-nucleotide adenylyltransferase NadD/hypothetical protein 0.0897 0.6937 1
Schistosoma mansoni biogenic amine (dopamine) receptor 0.0012 0.0013 0.0012
Trichomonas vaginalis pps1 dual specificty phosphatase, putative 0.0604 0.4649 1
Loa Loa (eye worm) FYVE zinc finger family protein 0.0014 0.0024 0.007
Schistosoma mansoni FTZ-F1 nuclear receptor-like protein 0.0042 0.0248 0.0246
Echinococcus multilocularis guanine nucleotide binding protein G(s) subunit 0.0285 0.2145 0.2144
Echinococcus multilocularis Nuclear hormone receptor HR96 0.002 0.0073 0.0072
Echinococcus granulosus histone lysine methyltransferase setb 0.008 0.0544 0.0543
Mycobacterium ulcerans bifunctional enzyme MbtA: salicyl-AMP ligase (SAL-AMP ligase) + salicyl-S-ACP synthetase 0.0029 0.0143 0.0204
Trypanosoma brucei DNA polymerase kappa, putative 0.004 0.0233 0.3379
Echinococcus multilocularis bromodomain adjacent to zinc finger domain 0.0036 0.0199 0.0198
Loa Loa (eye worm) hypothetical protein 0.002 0.0073 0.0221
Schistosoma mansoni zinc finger protein 0.002 0.0073 0.0072
Schistosoma mansoni peptide (FMRFamide/somatostatin)-like receptor 0.0012 0.0013 0.0012
Trypanosoma cruzi metacaspase 5, putative 0.0028 0.0134 0.195
Entamoeba histolytica ubiquitin carboxyl-terminal hydrolase domain containing protein 0.0075 0.0506 0.1087
Brugia malayi hypothetical protein 0.0012 0.0013 0.0036
Leishmania major phosphatidylinositol (3,5) kinase, putative 0.0014 0.0024 0.035
Trypanosoma cruzi myo-inositol-1(or 4)-monophosphatase 1, putative 0.0036 0.0197 0.286
Schistosoma mansoni Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) 0.0285 0.2145 0.2144
Schistosoma mansoni thyroid hormone receptor 0.0042 0.0248 0.0246
Schistosoma mansoni jumonji/arid domain-containing protein 0.0066 0.0434 0.0432
Trypanosoma brucei DNA polymerase kappa, putative 0.004 0.0233 0.3379
Echinococcus granulosus g-protein coupled receptor 0.0012 0.0013 0.0012
Loa Loa (eye worm) hypothetical protein 0.0073 0.049 0.15
Plasmodium falciparum LCCL domain-containing protein 0.0019 0.0067 0.0094
Trypanosoma brucei DNA polymerase kappa, putative 0.004 0.0233 0.3379
Brugia malayi SET domain containing protein 0.0011 0.0006 0.0014
Onchocerca volvulus 0.0012 0.0013 0.0031
Echinococcus multilocularis nuclear receptor 2DBD gamma 0.002 0.0073 0.0072
Loa Loa (eye worm) hypothetical protein 0.0012 0.0013 0.0036
Leishmania major DNA polymerase kappa, putative 0.004 0.0233 0.3379
Schistosoma mansoni methyl-cpg binding protein mbd 0.0017 0.0051 0.005
Echinococcus multilocularis histone lysine N methyltransferase MLL3 0.003 0.0154 0.0153
Onchocerca volvulus 0.0029 0.0143 0.038
Mycobacterium tuberculosis Probable fatty-acid-CoA ligase FadD2 (fatty-acid-CoA synthetase) (fatty-acid-CoA synthase) 0.0098 0.0684 0.0984
Schistosoma mansoni nuclear hormone receptor nor-1/nor-2 0.0042 0.0248 0.0246
Echinococcus multilocularis NADP dependent isocitrate dehydrogenase 0.0034 0.0184 0.0182
Brugia malayi hypothetical protein 0.0012 0.0013 0.0036
Schistosoma mansoni terminal deoxycytidyl transferase 0.004 0.0233 0.0231
Toxoplasma gondii Acetyl-coenzyme A synthetase 2, putative 0.0029 0.0143 0.1102
Echinococcus multilocularis isocitrate dehydrogenase 0.0034 0.0184 0.0182
Echinococcus granulosus guanine nucleotide binding protein G protein 0.0012 0.0013 0.0012
Echinococcus granulosus neuropeptides capa receptor 0.0012 0.0013 0.0012
Schistosoma mansoni importin beta-1 0.0029 0.0143 0.0142
Trichomonas vaginalis phosphatidylinositol-4-phosphate 5-kinase type II, putative 0.0014 0.0024 0.0049
Mycobacterium ulcerans aldehyde dehydrogenase 0.0061 0.0393 0.0565
Mycobacterium tuberculosis Probable fatty-acid-CoA ligase FadD8 (fatty-acid-CoA synthetase) (fatty-acid-CoA synthase) 0.0029 0.0143 0.0204
Plasmodium falciparum dihydrolipoyl dehydrogenase, apicoplast 0.0034 0.0184 0.0264
Trypanosoma cruzi ISWI complex protein 0.0015 0.0037 0.0544
Brugia malayi ATP-dependent DNA helicase, RecQ family protein 0.002 0.007 0.0212
Brugia malayi jmjC domain containing protein 0.0059 0.0378 0.1156
Echinococcus multilocularis 3 hydroxyacyl coenzyme A dehydrogenase type 2 0.0056 0.0359 0.0358
Brugia malayi Probable ClpP-like protease 0.016 0.117 0.3583
Leishmania major apurinic/apyrimidinic endonuclease-redox protein 0.0037 0.021 0.3046
Brugia malayi hypothetical protein 0.0345 0.2616 0.8018
Schistosoma mansoni tar DNA-binding protein 0.0061 0.0397 0.0395
Toxoplasma gondii ImpB/MucB/SamB family protein 0.0039 0.0223 0.1725
Echinococcus granulosus NADP dependent isocitrate dehydrogenase 0.0034 0.0184 0.0182
Brugia malayi Ligand-binding domain of nuclear hormone receptor family protein 0.0042 0.0248 0.0755
Mycobacterium ulcerans acyl-CoA synthetase 0.0029 0.0143 0.0204
Brugia malayi Pre-SET motif family protein 0.0063 0.0411 0.1255
Trichomonas vaginalis chromodomain helicase DNA binding protein, putative 0.002 0.0078 0.0165
Brugia malayi Latrophilin receptor protein 2 0.0065 0.0429 0.1311
Loa Loa (eye worm) CXXC zinc finger family protein 0.009 0.0626 0.1914
Mycobacterium ulcerans ATP-dependent Clp protease proteolytic subunit 0.016 0.117 0.1685
Plasmodium vivax ATP-dependent Clp protease proteolytic subunit, putative 0.016 0.117 0.1685
Plasmodium vivax dihydrolipoyl dehydrogenase, apicoplast, putative 0.0034 0.0184 0.0264
Trypanosoma brucei DNA polymerase kappa, putative 0.0028 0.0135 0.1959
Echinococcus multilocularis serotonin receptor 0.0012 0.0013 0.0012
Trypanosoma cruzi ATP-dependent DEAD/H DNA helicase recQ, putative 0.0025 0.0115 0.1675
Trypanosoma brucei dihydrolipoamide dehydrogenase 0.0034 0.0184 0.2678
Entamoeba histolytica myo-inositol monophosphatase, putative 0.0036 0.0197 0.0421
Echinococcus granulosus alpha 1A adrenergic receptor 0.0012 0.0013 0.0012
Brugia malayi acetyl-Coenzyme A synthetase 2 0.0029 0.0143 0.0433
Echinococcus granulosus 3 hydroxyacyl coenzyme A dehydrogenase type 2 0.0056 0.0359 0.0358
Loa Loa (eye worm) hypothetical protein 0.0025 0.0116 0.0352
Toxoplasma gondii hypothetical protein 0.0055 0.0349 0.2695
Brugia malayi putative neuropeptide receptor 0.0012 0.0013 0.0036
Brugia malayi Dopamine receptor protein 1 0.0012 0.0013 0.0036
Loa Loa (eye worm) inositol-1 0.0036 0.0197 0.06
Schistosoma mansoni nuclear receptor 0.002 0.0073 0.0072
Brugia malayi Guanine nucleotide-binding protein alpha-3 subunit, putative 0.0012 0.0013 0.0037
Echinococcus multilocularis ecdysone induced protein 78C 0.0042 0.0248 0.0246
Echinococcus multilocularis neuropeptides capa receptor 0.0012 0.0013 0.0012
Echinococcus multilocularis neuropeptide Y receptor 0.0012 0.0013 0.0012
Plasmodium falciparum isocitrate dehydrogenase [NADP], mitochondrial 0.0034 0.0184 0.0263
Loa Loa (eye worm) hypothetical protein 0.0042 0.0248 0.0755
Trichomonas vaginalis Clan CD, family C14, metacaspase-like cysteine peptidase 0.0028 0.0134 0.0286
Loa Loa (eye worm) 3-hydroxyacyl-CoA dehydrogenase type II 0.0053 0.033 0.1007
Leishmania major 2-oxoglutarate dehydrogenase, e3 component, lipoamidedehydrogenase-like protein 0.0034 0.0184 0.2678
Schistosoma mansoni acetyl-CoA synthetase 0.0029 0.0143 0.0141
Echinococcus granulosus rhodopsin orphan GPCR 0.0012 0.0013 0.0012
Schistosoma mansoni GTP-binding protein alpha subunit 0.0012 0.0013 0.0012
Trichomonas vaginalis chromodomain-helicase-DNA-binding protein, putative 0.002 0.0078 0.0165
Leishmania major hypothetical protein, conserved 0.0011 0.0001 0.0019
Toxoplasma gondii 4'-phosphopantetheinyl transferase domain-containing protein 0.0024 0.0107 0.0828
Echinococcus granulosus jumonji domain containing 1A 0.0016 0.004 0.0039
Trypanosoma cruzi cytidylyltransferase, putative 0.0011 0.0001 0.0019
Trypanosoma cruzi ubiquitin carboxyl-terminal hydrolase, putative 0.0075 0.0506 0.7353
Trypanosoma brucei GTP-binding nuclear protein rtb2, putative 0.0021 0.0084 0.1218
Trypanosoma cruzi metacaspase, putative 0.0028 0.0134 0.195
Brugia malayi larval opioid receptor 0.0012 0.0013 0.0036
Loa Loa (eye worm) hypothetical protein 0.0012 0.0013 0.0036
Echinococcus granulosus g protein coupled receptor 0.0012 0.0013 0.0012
Toxoplasma gondii phosphatidylinositol-4-phosphate 5-Kinase 0.0014 0.0024 0.0186
Loa Loa (eye worm) hypothetical protein 0.0012 0.0013 0.0036
Plasmodium falciparum nicotinamide/nicotinic acid mononucleotide adenylyltransferase 0.0897 0.6937 1
Echinococcus granulosus guanine nucleotide binding protein Gs subunit 0.0285 0.2145 0.2144
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0012 0.0013 0.0012
Entamoeba histolytica long-chain-fatty-acid--CoA ligase, putative 0.0029 0.0143 0.0304
Trichomonas vaginalis conserved hypothetical protein 0.0028 0.0134 0.0286
Brugia malayi Protein-tyrosine phosphatase containing protein 0.0123 0.0883 0.2703
Plasmodium falciparum pyruvate kinase 0.0033 0.0175 0.025
Echinococcus granulosus guanine nucleotide binding protein G protein 0.0012 0.0013 0.0012
Brugia malayi tailless protein 0.002 0.0073 0.0221
Schistosoma mansoni peptide (FMRFamide/somatostatin)-like receptor 0.0012 0.0013 0.0012
Trichomonas vaginalis glutathione reductase, putative 0.0034 0.0184 0.0394
Echinococcus multilocularis histone lysine N methyltransferase SETMAR 0.0063 0.0411 0.0409
Brugia malayi Serotonin receptor 0.0012 0.0013 0.0036
Toxoplasma gondii propionate-CoA ligase 0.0029 0.0143 0.1102
Echinococcus multilocularis lipoxygenase domain containing protein 0.0019 0.0067 0.0065
Leishmania major 4-coumarate:coa ligase-like protein 0.0098 0.0684 0.9934
Trypanosoma brucei DNA polymerase kappa, putative 0.004 0.0233 0.3379
Onchocerca volvulus 0.0012 0.0013 0.0031
Loa Loa (eye worm) nuclear hormone receptor-like 1 0.0022 0.0092 0.0278
Echinococcus multilocularis guanine nucleotide binding protein (G protein) 0.0012 0.0013 0.0012
Onchocerca volvulus 0.0012 0.0013 0.0031
Schistosoma mansoni hypothetical protein 0.0141 0.1022 0.1021
Echinococcus granulosus ubiquitin specific protease 41 0.0075 0.0506 0.0505
Toxoplasma gondii pyruvate kinase PyK1 0.0033 0.0175 0.1348
Loa Loa (eye worm) hypothetical protein 0.0012 0.0013 0.0036
Loa Loa (eye worm) hypothetical protein 0.0012 0.0013 0.0037
Loa Loa (eye worm) glutaminase 0.0276 0.2081 0.6379
Loa Loa (eye worm) hypothetical protein 0.0042 0.0248 0.0755
Leishmania major metacaspase, putative 0.0028 0.0134 0.195
Loa Loa (eye worm) hypothetical protein 0.0012 0.0013 0.0036
Schistosoma mansoni biogenic amine (dopamine) receptor 0.0012 0.0013 0.0012
Brugia malayi Nuclear hormone receptor family member nhr-40 0.0042 0.0248 0.0755
Trypanosoma cruzi apurinic/apyrimidinic endonuclease 0.0037 0.021 0.3046
Brugia malayi aminoadipate-semialdehyde dehydrogenase-phosphopantetheinyl transferase 0.0086 0.0592 0.1811
Trichomonas vaginalis conserved hypothetical protein 0.002 0.0078 0.0165
Schistosoma mansoni phosphatidylserine receptor 0.0016 0.004 0.0039
Schistosoma mansoni biogenic amine (5HT) receptor 0.0012 0.0013 0.0012
Echinococcus granulosus Nuclear hormone receptor HR96 0.002 0.0073 0.0072
Echinococcus multilocularis nuclear receptor 2DBD gamma 0.0042 0.0248 0.0246
Trypanosoma brucei importin beta-1 subunit, putative 0.0029 0.0143 0.2084
Brugia malayi AMP-binding enzyme family protein 0.0098 0.0684 0.2094
Leishmania major importin beta-1 subunit, putative 0.0023 0.0101 0.1464
Plasmodium vivax multidomain scavenger receptor, putative 0.0019 0.0067 0.0094
Leishmania major phosphatidylinositol-4-phosphate-5-kinase-likep ro tein 0.0014 0.0024 0.035
Schistosoma mansoni aminoadipate-semialdehyde dehydrogenase 0.0086 0.0592 0.0591
Onchocerca volvulus Nuclear receptor subfamily 6 group A member 1 homolog 0.002 0.0073 0.0193
Echinococcus multilocularis cadherin EGF LAG seven pass G type receptor 0.0065 0.0429 0.0428
Schistosoma mansoni acetyl-CoA C-acetyltransferase 0.0028 0.0135 0.0133
Plasmodium vivax glutathione reductase, putative 0.0098 0.0688 0.0989
Trypanosoma cruzi JmjC domain, hydroxylase, putative 0.0016 0.004 0.0588
Onchocerca volvulus 0.0012 0.0013 0.0031
Loa Loa (eye worm) hypothetical protein 0.0012 0.0013 0.0036
Schistosoma mansoni nuclear receptor 2DBD-gamma 0.0042 0.0248 0.0246
Entamoeba histolytica recQ family helicase, putative 0.0025 0.0115 0.0245
Brugia malayi hypothetical protein 0.0022 0.0092 0.0278
Brugia malayi hypothetical protein 0.0123 0.0877 0.2686
Echinococcus granulosus lipoxygenase domain containing protein 0.0019 0.0067 0.0065
Trypanosoma cruzi hypothetical protein, conserved 0.0077 0.052 0.755
Trichomonas vaginalis helicase, putative 0.002 0.0078 0.0165
Brugia malayi G protein-coupled receptor F59B2.13 0.0012 0.0013 0.0036
Mycobacterium tuberculosis Probable nicotinate-nucleotide adenylyltransferase NadD (deamido-NAD(+) pyrophosphorylase) (deamido-NAD(+) diphosphorylase) (nic 0.0897 0.6937 1
Onchocerca volvulus 0.0019 0.0067 0.0176
Echinococcus granulosus ATP dependent DNA helicase Q1 0.002 0.007 0.0069
Echinococcus multilocularis phd:f box containing protein 0.0016 0.004 0.0039
Echinococcus multilocularis g protein linked acetylcholine receptor gar 2a 0.0012 0.0013 0.0012
Plasmodium falciparum phosphatidylinositol-4-phosphate 5-kinase 0.0014 0.0024 0.0033
Echinococcus multilocularis expressed protein 0.0035 0.0189 0.0187
Schistosoma mansoni amine GPCR 0.0012 0.0013 0.0012
Echinococcus granulosus lamin 0.0055 0.0345 0.0344
Treponema pallidum hypothetical protein 0.0897 0.6937 1
Echinococcus multilocularis bromodomain adjacent to zinc finger domain 0.0065 0.0426 0.0424
Echinococcus multilocularis tm gpcr rhodopsin gpcr rhodopsin superfamily 0.0012 0.0013 0.0012
Echinococcus multilocularis 7TM GPCR, rhodopsin 0.0012 0.0013 0.0012
Echinococcus multilocularis atpase aaa+ type core atpase aaa type core 0.0801 0.6186 0.6186
Echinococcus multilocularis neuropeptide Y receptor 0.0012 0.0013 0.0012
Trypanosoma cruzi myo-inositol-1(or 4)-monophosphatase 1, putative 0.0036 0.0197 0.286
Toxoplasma gondii ATP-dependent Clp endopeptidase, proteolytic subunit ClpP domain-containing protein 0.016 0.117 0.9034
Loa Loa (eye worm) protein-tyrosine phosphatase 0.0123 0.0883 0.2703
Schistosoma mansoni hypothetical protein 0.0065 0.0429 0.0428
Loa Loa (eye worm) hypothetical protein 0.0012 0.0013 0.0036
Schistosoma mansoni steroid hormone receptor ad4bp 0.0042 0.0248 0.0246
Mycobacterium ulcerans hypothetical protein 0.0012 0.0015 0.002
Loa Loa (eye worm) nuclear hormone receptor family member nhr-31 0.0042 0.0248 0.0755
Loa Loa (eye worm) hypothetical protein 0.0012 0.0013 0.0036
Echinococcus multilocularis retinoic acid receptor rxr beta a retinoic acid receptor rxr alpha a retinoic acid receptor rxr alpha 0.002 0.0073 0.0072
Echinococcus granulosus Polycystic kidney disease protein 0.0019 0.0067 0.0065
Brugia malayi cytoplasmic intermediate filament protein 0.0029 0.0147 0.0446
Mycobacterium tuberculosis Probable aldehyde dehydrogenase 0.0061 0.0393 0.0565
Loa Loa (eye worm) hypothetical protein 0.0055 0.0345 0.1055
Echinococcus granulosus expressed protein 0.0012 0.0013 0.0012
Trichomonas vaginalis DNA helicase recq, putative 0.0047 0.0288 0.0616
Mycobacterium leprae PROBABLE ATP-DEPENDENT CLP PROTEASE PROTEOLYTIC SUBUNIT 2 CLPP2 (ENDOPEPTIDASE CLP 2) 0.016 0.117 0.1685
Mycobacterium leprae ATP-dependent Clp protease proteolytic subunit 1 0.0055 0.0349 0.0501
Loa Loa (eye worm) hypothetical protein 0.0012 0.0013 0.0036
Wolbachia endosymbiont of Brugia malayi phosphopantetheine adenylyltransferase 0.0011 0.0001 0.0011
Echinococcus multilocularis dihydrolipoamide dehydrogenase 0.0034 0.0184 0.0183
Schistosoma mansoni peptide (allatostatin/somatostatin)-like receptor 0.0012 0.0013 0.0012
Plasmodium falciparum glutathione reductase 0.0034 0.0184 0.0264
Brugia malayi guanine nucleotide-binding protein G(o), alpha subunit, putative 0.0012 0.0013 0.0037
Brugia malayi conserved hypotetical protein 0.002 0.0073 0.0221
Brugia malayi latrophilin 2 splice variant baaae 0.0141 0.1022 0.313
Echinococcus granulosus allatostatin A receptor 0.0012 0.0013 0.0012
Loa Loa (eye worm) hypothetical protein 0.0012 0.0013 0.0036
Loa Loa (eye worm) PLK/PLK1 protein kinase 0.0098 0.0689 0.2108
Treponema pallidum NADH oxidase 0.0034 0.0184 0.0264
Schistosoma mansoni hypothetical protein 0.0086 0.0594 0.0592
Onchocerca volvulus 0.0012 0.0013 0.0031
Echinococcus multilocularis RUN 0.0019 0.0067 0.0065
Toxoplasma gondii pyruvate kinase PyKII 0.0017 0.0049 0.0382
Plasmodium falciparum holo-[acyl-carrier-protein] synthase, putative 0.0024 0.0107 0.0153
Toxoplasma gondii ICE family protease (caspase) p20 domain-containing protein 0.0028 0.0134 0.1037
Brugia malayi Bloom's syndrome protein homolog 0.0047 0.0288 0.0878
Schistosoma mansoni rotamase 0.0035 0.0189 0.0187
Trichomonas vaginalis GTP-binding protein (z) alpha subunit, gnaz, putative 0.0012 0.0013 0.0026
Loa Loa (eye worm) hypothetical protein 0.0012 0.0013 0.0036
Echinococcus multilocularis lipoxygenase domain containing protein 0.0019 0.0067 0.0065
Brugia malayi Unidentified vitellogenin-linked transcript protein 6, putative 0.0012 0.0013 0.0036
Brugia malayi jmjC domain containing protein 0.0016 0.004 0.012
Trypanosoma cruzi phosphatidylinositol-4-phosphate 5-kinase, putative 0.0014 0.0024 0.035
Trypanosoma brucei DNA polymerase kappa, putative 0.0012 0.0015 0.0224
Leishmania major cholinephosphate cytidylyltransferase A, putative 0.0011 0.0001 0.0019
Brugia malayi GnHR receptor homolog 0.0012 0.0013 0.0036
Echinococcus multilocularis importin subunit beta 1 0.0029 0.0143 0.0142
Echinococcus granulosus mixed lineage leukemia protein mll 0.0025 0.0111 0.011
Schistosoma mansoni opsin-like receptor 0.0012 0.0013 0.0012
Schistosoma mansoni caspase-3 (C14 family) 0.0028 0.0134 0.0133
Echinococcus multilocularis alpha 1A adrenergic receptor 0.0012 0.0013 0.0012
Loa Loa (eye worm) pyruvate kinase-PB 0.0023 0.0097 0.0293
Trypanosoma cruzi apurinic/apyrimidinic endonuclease, putative 0.0037 0.021 0.3046
Plasmodium vivax AP endonuclease (DNA-[apurinic or apyrimidinic site] lyase), putative 0.0037 0.021 0.03
Trypanosoma brucei DNA polymerase kappa, putative 0.0028 0.0135 0.1959
Loa Loa (eye worm) isocitrate dehydrogenase 0.0034 0.0184 0.0559
Echinococcus granulosus intermediate filament protein 0.0055 0.0345 0.0344
Echinococcus granulosus histone lysine N methyltransferase MLL3 0.003 0.0154 0.0153
Entamoeba histolytica acyl-CoA synthetase, putative 0.0098 0.0684 0.1469
Toxoplasma gondii aldehyde dehydrogenase 0.0061 0.0393 0.3037
Mycobacterium tuberculosis Probable fatty-acid-CoA ligase FadD5 (fatty-acid-CoA synthetase) (fatty-acid-CoA synthase) 0.0069 0.0459 0.066
Echinococcus multilocularis Phosphatidylinositol 4 phosphate 5 kinase type 1 0.0014 0.0024 0.0023
Leishmania major pantothenate kinase subunit, putative 0.0012 0.0008 0.0115
Schistosoma mansoni histone-lysine n-methyltransferase suv9 0.0063 0.0411 0.0409
Echinococcus granulosus phd:f box containing protein 0.0016 0.004 0.0039
Loa Loa (eye worm) hypothetical protein 0.0206 0.1533 0.4698
Schistosoma mansoni Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) 0.0285 0.2145 0.2144
Loa Loa (eye worm) RNA recognition domain-containing protein domain-containing protein 0.0061 0.0397 0.1213
Schistosoma mansoni GTP-binding protein alpha subunit 0.0012 0.0013 0.0012
Schistosoma mansoni NADP-specific isocitrate dehydrogenase 0.0034 0.0184 0.0182
Brugia malayi Pip kinase protein 1 0.0014 0.0024 0.007
Leishmania major hypothetical protein, conserved 0.0016 0.004 0.0588
Loa Loa (eye worm) hypothetical protein 0.002 0.0073 0.0221
Trypanosoma cruzi DNA polymerase kappa, putative 0.004 0.0233 0.3379
Brugia malayi Dopamine receptor protein 2 0.0012 0.0013 0.0036
Trypanosoma cruzi phosphatidylinositol-4-phosphate 5-kinase, putative 0.0014 0.0024 0.035
Brugia malayi gonadotropin-releasing hormone receptor 2 0.0012 0.0013 0.0036
Trichomonas vaginalis ran, putative 0.0021 0.0084 0.0178
Trichomonas vaginalis myo inositol monophosphatase, putative 0.0036 0.0197 0.0421
Schistosoma mansoni caspase-7 (C14 family) 0.0028 0.0134 0.0133
Echinococcus granulosus caspase 2 0.0028 0.0134 0.0133
Trichomonas vaginalis ap endonuclease, putative 0.0037 0.021 0.0448
Brugia malayi nuclear receptor RXR 0.0022 0.0092 0.0278
Echinococcus multilocularis pyroglutamylated rfamide peptide receptor 0.0012 0.0013 0.0012
Mycobacterium ulcerans extragenic suppressor protein SuhB 0.0036 0.0197 0.0282
Echinococcus multilocularis fetal alzheimer antigen, falz 0.0028 0.0135 0.0133
Brugia malayi Bromodomain containing protein 0.0038 0.0218 0.0663
Echinococcus granulosus serine:threonine protein kinase PLK1 0.0098 0.0689 0.0687
Echinococcus granulosus rhodopsin orphan GPCR 0.0012 0.0013 0.0012
Brugia malayi guanine nucleotide-binding protein alpha-3 subunit, putative 0.0012 0.0013 0.0037
Echinococcus granulosus FTZ F1 alpha 0.0042 0.0248 0.0246
Trichomonas vaginalis CAMK family protein kinase 0.0098 0.0689 0.1479
Loa Loa (eye worm) hypothetical protein 0.0012 0.0013 0.0036
Brugia malayi beta-lactamase 0.0077 0.052 0.159
Trichomonas vaginalis Clan CD, family C14, metacaspase-like cysteine peptidase 0.0028 0.0134 0.0286
Brugia malayi photoreceptor-specific nuclear receptor 0.0042 0.0248 0.0755
Loa Loa (eye worm) PHD-finger family protein 0.0021 0.0079 0.0239
Trypanosoma cruzi ethanolamine-phosphate cytidylyltransferase 0.0011 0.0001 0.0019
Trichomonas vaginalis glutaminase, putative 0.0276 0.2081 0.4475
Schistosoma mansoni tar DNA-binding protein 0.0061 0.0397 0.0395
Mycobacterium tuberculosis Probable esterase/lipase LipP 0.0077 0.052 0.0748
Echinococcus granulosus phosphatidylinositol phosphate 5 kinase type III 0.0014 0.0024 0.0023
Leishmania major ATP-dependent DEAD/H DNA helicase recQ, putative 0.0025 0.0115 0.1675
Onchocerca volvulus Pyruvate kinase homolog 0.0033 0.0175 0.0465
Loa Loa (eye worm) hypothetical protein 0.0086 0.0592 0.1811
Schistosoma mansoni DNA helicase recq5 0.002 0.007 0.0069
Giardia lamblia Ubiquitin carboxyl-terminal hydrolase 4 0.0075 0.0506 0.7348
Echinococcus granulosus caspase 8 0.0028 0.0134 0.0133
Plasmodium falciparum ataxin-2 like protein, putative 0.0026 0.0122 0.0174
Trichomonas vaginalis chromodomain-helicase-DNA-binding protein, putative 0.0011 0.0004 0.0005
Schistosoma mansoni nuclear hormone receptor 0.002 0.0073 0.0072
Brugia malayi FYVE finger-containing phosphoinositide kinase, putative 0.0014 0.0024 0.007
Echinococcus multilocularis NADP dependent isocitrate dehydrogenase 0.0034 0.0184 0.0182
Echinococcus multilocularis G protein coupled 5 hydroxytryptamine receptor 0.0012 0.0013 0.0012
Mycobacterium leprae POSSIBLE FATTY-ACID-CoA LIGASE FADD10 (FATTY-ACID-CoA SYNTHETASE) (FATTY-ACID-CoA SYNTHASE) 0.0029 0.0143 0.0204
Trypanosoma brucei DNA polymerase kappa, putative 0.004 0.0233 0.3379
Plasmodium vivax phosphatidylinositol-4-phosphate 5-kinase, putative 0.0014 0.0024 0.0033
Brugia malayi Pyruvate kinase, M2 isozyme 0.0033 0.0175 0.0531
Trichomonas vaginalis DNA polymerase IV / kappa, putative 0.004 0.0233 0.0498
Echinococcus multilocularis rhodopsin orphan GPCR 0.0012 0.0013 0.0012
Trypanosoma brucei hypothetical protein, conserved 0.0011 0.0001 0.0019
Echinococcus multilocularis tm gpcr rhodopsin gpcr rhodopsin superfamily 0.0012 0.0013 0.0012
Echinococcus multilocularis growth hormone secretagogue receptor type 1 0.0012 0.0013 0.0012
Trypanosoma cruzi acetyl-CoA synthetase, putative 0.0029 0.0143 0.2072
Schistosoma mansoni phosphatidylinositol-4-phosphate 5-kinase type II 0.0169 0.1244 0.1243
Loa Loa (eye worm) hypothetical protein 0.0012 0.0013 0.0036
Echinococcus multilocularis mixed lineage leukemia protein mll 0.0025 0.0111 0.011
Onchocerca volvulus 0.0012 0.0013 0.0032
Onchocerca volvulus 0.0098 0.0684 0.1835
Echinococcus granulosus G protein coupled 5 hydroxytryptamine receptor 0.0012 0.0013 0.0012
Loa Loa (eye worm) hypothetical protein 0.0012 0.0013 0.0036
Loa Loa (eye worm) hypothetical protein 0.0022 0.0092 0.0278
Onchocerca volvulus 0.0012 0.0013 0.0032
Toxoplasma gondii phosphatidylinositol-4-phosphate 5-kinase 0.0014 0.0024 0.0186
Brugia malayi RNA binding protein 0.0061 0.0397 0.1213
Mycobacterium ulcerans dihydrolipoamide dehydrogenase, LpdB 0.0034 0.0184 0.0264
Schistosoma mansoni ubiquitin-specific peptidase 2 (C19 family) 0.0075 0.0506 0.0505
Brugia malayi Nuclear hormone receptor-like 1 0.0022 0.0092 0.0278
Loa Loa (eye worm) G-protein coupled receptor 0.0012 0.0013 0.0036
Loa Loa (eye worm) hypothetical protein 0.0022 0.0092 0.0278
Mycobacterium ulcerans phosphopantetheinyl transferase, PptII 0.0024 0.0107 0.0153
Schistosoma mansoni retinoid-x-receptor (RXR) 0.0042 0.0248 0.0246
Echinococcus multilocularis diuretic hormone 44 receptor GPRdih2 0.0065 0.0429 0.0428
Schistosoma mansoni blooms syndrome DNA helicase 0.0037 0.021 0.0209
Echinococcus multilocularis rhodopsin orphan GPCR 0.0012 0.0013 0.0012
Leishmania major DNA polymerase kappa, putative,DNA polymerase IV, putative 0.004 0.0233 0.3379
Schistosoma mansoni pyruvate kinase 0.0017 0.0049 0.0048
Plasmodium falciparum importin beta, putative 0.0029 0.0143 0.0205
Echinococcus multilocularis guanine nucleotide binding protein (G protein) 0.0012 0.0013 0.0012
Entamoeba histolytica acyl-CoA synthetase, putative 0.0098 0.0684 0.1469
Brugia malayi G-protein-linked acetylcholine receptor protein 2, putative 0.0012 0.0013 0.0036
Echinococcus granulosus rhodopsin orphan GPCR 0.0012 0.0013 0.0012
Trichomonas vaginalis GTP-binding protein (q) alpha-11 subunit, gna11, putative 0.0012 0.0013 0.0026
Loa Loa (eye worm) melatonin receptor type 1A 0.0012 0.0013 0.0036
Leishmania major trypanothione reductase 0.0098 0.0688 0.9984
Schistosoma mansoni photoreceptor-specific nuclear receptor related 0.0042 0.0248 0.0246
Echinococcus multilocularis pyruvate kinase 0.0033 0.0175 0.0173
Loa Loa (eye worm) hypothetical protein 0.0012 0.0013 0.0036
Schistosoma mansoni biogenic amine (octopamine/dopamine) receptor 0.0012 0.0013 0.0012
Loa Loa (eye worm) hypothetical protein 0.0012 0.0013 0.0037
Schistosoma mansoni Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) 0.0285 0.2145 0.2144
Trypanosoma cruzi polo-like protein kinase, putative 0.0098 0.0689 1
Echinococcus multilocularis histone lysine N methyltransferase MLL3 0.0025 0.0111 0.011
Echinococcus granulosus tyrosine protein phosphatase non receptor type 0.0123 0.0883 0.0881
Brugia malayi ecdysone receptor 0.002 0.0073 0.0221
Loa Loa (eye worm) hypothetical protein 0.0012 0.0015 0.0043
Schistosoma mansoni hypothetical protein 0.0021 0.0079 0.0078
Echinococcus granulosus hepatocyte nuclear factor 4 alpha 0.0042 0.0248 0.0246
Trypanosoma brucei acetyl-CoA synthetase, putative 0.0029 0.0143 0.2072
Brugia malayi nuclear hormone receptor 0.0042 0.0248 0.0755
Echinococcus multilocularis cpg binding protein 0.0097 0.0681 0.068
Trypanosoma brucei dihydrolipoyl dehydrogenase 0.0034 0.0184 0.2678
Brugia malayi Importin beta-1 subunit 0.0029 0.0143 0.0436
Mycobacterium ulcerans hypothetical protein 0.0098 0.0684 0.0984
Trichomonas vaginalis GTP-binding protein alpha subunit, gna, putative 0.0012 0.0013 0.0026
Leishmania major hypothetical protein, conserved 0.0026 0.0122 0.1772
Trichomonas vaginalis chromodomain-helicase-DNA-binding protein, putative 0.002 0.0078 0.0165
Schistosoma mansoni histamine h1 receptor 0.0012 0.0013 0.0012
Schistosoma mansoni methyl-cpg binding protein mbd 0.0017 0.0051 0.005
Echinococcus multilocularis sex peptide receptor 0.0012 0.0013 0.0012
Trichomonas vaginalis chromodomain helicase DNA binding protein, putative 0.002 0.0078 0.0165
Schistosoma mansoni biogenic amine (dopamine) receptor 0.0012 0.0013 0.0012
Loa Loa (eye worm) hypothetical protein 0.0098 0.0684 0.2094
Echinococcus granulosus Phosphatidylinositol 4 phosphate 5 kinase type 1 0.0014 0.0024 0.0023
Brugia malayi glutathione reductase 0.0098 0.0688 0.2104
Brugia malayi AMP-binding enzyme family protein 0.0098 0.0684 0.2094
Schistosoma mansoni amine GPCR 0.0012 0.0013 0.0012
Echinococcus granulosus fmrfamide receptor 0.0012 0.0013 0.0012
Brugia malayi Corticotropin releasing factor receptor 2 precursor, putative 0.0206 0.1533 0.4698
Loa Loa (eye worm) thioredoxin reductase 0.0098 0.0688 0.2104
Brugia malayi GTP-binding regulatory protein alpha chain - starfish, putative 0.0012 0.0013 0.0037
Loa Loa (eye worm) hypothetical protein 0.0012 0.0013 0.0036
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0012 0.0013 0.0012
Trypanosoma brucei DNA polymerase IV, putative 0.004 0.0233 0.3379
Schistosoma mansoni DNA helicase recq1 0.002 0.007 0.0069
Echinococcus granulosus lipoxygenase domain containing protein 0.0019 0.0067 0.0065
Trypanosoma brucei metacaspase 5, putative 0.0028 0.0134 0.195
Brugia malayi polk-prov protein 0.0012 0.0015 0.0043
Echinococcus multilocularis rhodopsin orphan GPCR 0.0012 0.0013 0.0012
Entamoeba histolytica peptidyl-prolyl cis-trans isomerase, putative 0.0034 0.0182 0.0389
Loa Loa (eye worm) hypothetical protein 0.0038 0.0218 0.0665
Leishmania major acetoin dehydrogenase e3 component-like protein 0.0034 0.0184 0.2678
Brugia malayi jmjC domain containing protein 0.0016 0.004 0.012
Onchocerca volvulus 0.0012 0.0013 0.0031
Loa Loa (eye worm) hypothetical protein 0.0022 0.0092 0.0278
Leishmania major acetyl-CoA synthetase, putative 0.0029 0.0143 0.2072
Brugia malayi hypothetical protein 0.0012 0.0013 0.0036
Echinococcus granulosus rhodopsin orphan GPCR 0.0012 0.0013 0.0012
Mycobacterium tuberculosis Probable exodeoxyribonuclease III protein XthA (exonuclease III) (EXO III) (AP endonuclease VI) 0.0037 0.021 0.03
Loa Loa (eye worm) RNA binding protein 0.0061 0.0397 0.1213
Trichomonas vaginalis DNA polymerase eta, putative 0.004 0.0233 0.0498
Echinococcus granulosus Jumonji AT rich interactive domain 1B 0.0023 0.0096 0.0094
Echinococcus multilocularis guanine nucleotide binding protein G(s) subunit 0.0285 0.2145 0.2144
Schistosoma mansoni subfamily C14A unassigned peptidase (C14 family) 0.0028 0.0134 0.0133
Echinococcus granulosus nuclear receptor subfamily 4 group A 0.002 0.0073 0.0072
Brugia malayi hypothetical protein 0.0012 0.0013 0.0037
Mycobacterium ulcerans acyl-CoA synthetase 0.0098 0.0684 0.0984
Brugia malayi hypothetical protein 0.002 0.0073 0.0221
Loa Loa (eye worm) nuclear Hormone Receptor family member 0.0042 0.0248 0.0755
Schistosoma mansoni hypothetical protein 0.0086 0.0594 0.0592
Echinococcus multilocularis L aminoadipate semialdehyde 0.0086 0.0592 0.0591
Trypanosoma cruzi PAB1-binding protein , putative 0.0026 0.0122 0.1772
Schistosoma mansoni 3-hydroxyacyl-CoA dehydrogenase 0.0056 0.0359 0.0358
Onchocerca volvulus 0.0012 0.0013 0.0031
Echinococcus multilocularis lysine specific demethylase 6a 0.0016 0.004 0.0039
Loa Loa (eye worm) AMP-binding enzyme family protein 0.0029 0.0143 0.0433
Mycobacterium tuberculosis P-hydroxybenzoyl-AMP ligase FadD22 0.0029 0.0143 0.0204
Echinococcus multilocularis jumonji domain containing 1A 0.0016 0.004 0.0039
Echinococcus granulosus pyruvate kinase 0.0017 0.0049 0.0048
Brugia malayi nuclear receptor NHR-67 0.002 0.0073 0.0221
Loa Loa (eye worm) hypothetical protein 0.0012 0.0013 0.0036
Toxoplasma gondii histone lysine demethylase JMJC1/KDM5D/JARID1D 0.0016 0.004 0.0313
Echinococcus multilocularis tachykinin peptides receptor 99D 0.0012 0.0013 0.0012
Schistosoma mansoni phosphatidylinositol-4-phosphate 5-kinase type I 0.0014 0.0024 0.0023
Echinococcus granulosus tm gpcr rhodopsin 0.0012 0.0013 0.0012
Mycobacterium ulcerans acyl-CoA synthetase 0.0029 0.0143 0.0204
Toxoplasma gondii thioredoxin reductase 0.0098 0.0688 0.5309
Schistosoma mansoni adenoreceptor 0.0012 0.0013 0.0012
Echinococcus granulosus peptide allatostatin:somatostatin 0.0012 0.0013 0.0012
Mycobacterium tuberculosis Probable reductase 0.0224 0.1674 0.2412
Schistosoma mansoni kinase 0.005 0.0309 0.0308
Toxoplasma gondii ABC1 family protein 0.0077 0.052 0.4015
Brugia malayi Pyruvate kinase, muscle isozyme 0.0033 0.0175 0.0531
Schistosoma mansoni nuclear hormone receptor 0.002 0.0073 0.0072
Loa Loa (eye worm) beta-lactamase 0.0077 0.052 0.159
Schistosoma mansoni GTP-binding protein (I) alpha subunit gnai 0.0012 0.0013 0.0012
Schistosoma mansoni tar DNA-binding protein 0.0061 0.0397 0.0395
Trypanosoma brucei ATP-dependent DEAD/H DNA helicase recQ, putative 0.0025 0.0115 0.1675
Leishmania major peptidyl-prolyl cis-trans isomerase/rotamase, putative,PPIase, putative 0.0034 0.0182 0.2645
Trichomonas vaginalis penicillin-binding protein, putative 0.0077 0.052 0.1116
Brugia malayi steroid hormone receptor 0.0042 0.0248 0.0755
Loa Loa (eye worm) hypothetical protein 0.0012 0.0013 0.0037
Plasmodium falciparum JmjC domain-containing protein, putative 0.0016 0.004 0.0056
Mycobacterium ulcerans non-ribosomal peptide synthetase MbtE 0.0029 0.0143 0.0204
Loa Loa (eye worm) hypothetical protein 0.0012 0.0013 0.0036
Loa Loa (eye worm) hypothetical protein 0.0012 0.0013 0.0036
Echinococcus granulosus rhodopsin orphan GPCR 0.0012 0.0013 0.0012
Echinococcus granulosus diuretic hormone 44 receptor GPRdih2 0.0065 0.0429 0.0428
Echinococcus granulosus neuropeptide receptor A26 0.0473 0.3617 0.3616
Giardia lamblia Phosphatidylinositol-4-phosphate 5-kinase, putative 0.0014 0.0024 0.0332
Echinococcus granulosus somatostatin receptor 0.0012 0.0013 0.0012
Entamoeba histolytica deoxycytidyl transferase, putative 0.004 0.0233 0.0498
Trypanosoma brucei metacaspase 0.0028 0.0134 0.195
Schistosoma mansoni lamin 0.0055 0.0345 0.0344
Mycobacterium tuberculosis Probable peptide synthetase Nrp (peptide synthase) 0.0029 0.0143 0.0204
Leishmania major DNA polymerase kappa, putative 0.0012 0.0015 0.0224
Brugia malayi AMP-binding enzyme family protein 0.0029 0.0143 0.0433
Trichomonas vaginalis ap endonuclease, putative 0.0037 0.021 0.0448
Onchocerca volvulus 0.0029 0.0143 0.038
Echinococcus granulosus lysine specific demethylase 6a 0.0016 0.004 0.0039
Trichomonas vaginalis pyruvate kinase, putative 0.0033 0.0175 0.0373
Toxoplasma gondii cholinephosphate cytidylyltransferase 0.0011 0.0001 0.001
Schistosoma mansoni histamine-responsive GPCR (AAF21638) 0.0012 0.0013 0.0012
Schistosoma mansoni biogenic amine receptor 0.0012 0.0013 0.0012
Mycobacterium tuberculosis Conserved protein 0.0077 0.052 0.0748
Echinococcus granulosus pyruvate kinase 0.0033 0.0175 0.0173
Echinococcus multilocularis nuclear receptor nhr 48 0.002 0.0073 0.0072
Onchocerca volvulus 0.0012 0.0013 0.0031
Echinococcus granulosus tyrosine protein phosphatase non receptor type 0.0123 0.0883 0.0881
Loa Loa (eye worm) hypothetical protein 0.0028 0.0134 0.0408
Loa Loa (eye worm) nuclear hormone receptor family member nhr-41 0.0042 0.0248 0.0755
Schistosoma mansoni hypothetical protein 0.0015 0.0037 0.0036
Trichomonas vaginalis set domain proteins, putative 0.0486 0.3722 0.8005
Brugia malayi Ubiquitin carboxyl-terminal hydrolase family protein 0.0075 0.0506 0.1549
Echinococcus granulosus lamin dm0 0.0055 0.0345 0.0344
Trichomonas vaginalis CAMK family protein kinase 0.0098 0.0689 0.1479
Schistosoma mansoni neuropeptide F-like receptor 0.0012 0.0013 0.0012
Echinococcus granulosus dna polymerase kappa 0.004 0.0233 0.0231
Trichomonas vaginalis rotamase, putative 0.0035 0.0189 0.0403
Mycobacterium tuberculosis Probable ATP-dependent CLP protease proteolytic subunit 1 ClpP1 (endopeptidase CLP) 0.0105 0.0738 0.1063
Mycobacterium ulcerans flavoprotein disulfide reductase 0.0034 0.0184 0.0264
Toxoplasma gondii histone lysine methyltransferase SET/SUV39 0.0063 0.0411 0.3171
Onchocerca volvulus 0.0012 0.0013 0.0031
Giardia lamblia NADH oxidase lateral transfer candidate 0.0034 0.0184 0.2664
Echinococcus granulosus thyroid hormone receptor alpha 0.002 0.0073 0.0072
Schistosoma mansoni amine GPCR 0.0012 0.0013 0.0012
Brugia malayi orphan nuclear receptor NR2E1 0.002 0.0073 0.0221
Loa Loa (eye worm) hypothetical protein 0.0019 0.0067 0.0201
Echinococcus granulosus tm gpcr rhodopsin 0.0012 0.0013 0.0012
Brugia malayi calcium-independent alpha-latrotoxin receptor 2, putative 0.0065 0.0429 0.1311
Trichomonas vaginalis chromodomain helicase DNA binding protein, putative 0.002 0.0078 0.0165
Schistosoma mansoni GTP-binding protein (I) alpha-2 subunit gnai2 0.0012 0.0013 0.0012
Mycobacterium ulcerans short-chain type dehydrogenase/reductase 0.0056 0.0359 0.0516
Mycobacterium tuberculosis Probable lipase LipD 0.0077 0.052 0.0748
Loa Loa (eye worm) intermediate filament protein 0.0055 0.0345 0.1055
Echinococcus granulosus Transcription factor JmjC domain containing protein 0.0059 0.0378 0.0377
Trypanosoma brucei DNA polymerase kappa, putative 0.004 0.0233 0.3379
Trypanosoma brucei inositol-1(or 4)-monophosphatase 1, putative 0.0036 0.0197 0.286
Trypanosoma brucei dihydrolipoamide dehydrogenase, point mutation 0.0034 0.0184 0.2678
Schistosoma mansoni jumonji domain containing protein 0.0016 0.004 0.0039
Loa Loa (eye worm) hypothetical protein 0.0026 0.0124 0.0376
Leishmania major GTP-binding protein, putative 0.0021 0.0084 0.1218
Echinococcus multilocularis neuropeptide s receptor 0.0473 0.3617 0.3616
Schistosoma mansoni hypothetical protein 0.0086 0.0594 0.0592
Brugia malayi Thioredoxin reductase 0.0098 0.0688 0.2104
Echinococcus granulosus peptidase Clp S14 family 0.0105 0.0738 0.0737
Echinococcus multilocularis geminin 0.0731 0.564 0.564
Onchocerca volvulus 0.0345 0.2616 0.7027
Brugia malayi Nuclear hormone receptor family member nhr-19 0.0042 0.0248 0.0755
Plasmodium vivax hypothetical protein, conserved 0.0028 0.0134 0.0192
Schistosoma mansoni phosphatidylinositol-4-phosphate 5-kinase type II 0.0169 0.1244 0.1243
Plasmodium vivax hypothetical protein, conserved 0.0077 0.052 0.0748
Echinococcus granulosus g protein linked acetylcholine receptor gar 2a 0.0012 0.0013 0.0012
Brugia malayi Nuclear hormone receptor family member nhr-31 0.0042 0.0248 0.0755
Echinococcus multilocularis Bcl 2 ous antagonist:killer 0.0086 0.0594 0.0592
Schistosoma mansoni rab6-interacting 0.0019 0.0067 0.0065
Onchocerca volvulus 0.0012 0.0013 0.0031
Echinococcus multilocularis tyrosine protein phosphatase non receptor type 0.0123 0.0883 0.0881
Loa Loa (eye worm) hypothetical protein 0.0012 0.0013 0.0036
Schistosoma mansoni GTP-binding protein (I) alpha-1subunit gnai1 0.0012 0.0013 0.0012
Loa Loa (eye worm) hypothetical protein 0.0012 0.0013 0.0036
Trypanosoma cruzi DNA damage repair protein, putative 0.0012 0.0015 0.0224
Loa Loa (eye worm) hypothetical protein 0.0012 0.0013 0.0036
Brugia malayi hypothetical protein 0.0012 0.0013 0.0036
Mycobacterium ulcerans aldehyde dehydrogenase 0.0061 0.0393 0.0565
Echinococcus granulosus neuropeptide FF receptor 2 0.0012 0.0013 0.0012
Wolbachia endosymbiont of Brugia malayi exonuclease III 0.0037 0.021 0.1793
Brugia malayi nuclear hormone receptor 0.002 0.0073 0.0221
Loa Loa (eye worm) hypothetical protein 0.0023 0.0097 0.0293
Toxoplasma gondii AMP-binding enzyme domain-containing protein 0.0029 0.0143 0.1102
Trichomonas vaginalis CAMK family protein kinase 0.0098 0.0689 0.1479
Brugia malayi GTP-binding regulatory protein Gs alpha-S chain, putative 0.0285 0.2145 0.6575
Schistosoma mansoni thyroid hormone receptor 0.0042 0.0248 0.0246
Brugia malayi Guanine nucleotide-binding protein alpha-6 subunit, putative 0.0012 0.0013 0.0037
Echinococcus granulosus guanine nucleotide binding protein subunit 0.0012 0.0013 0.0012
Toxoplasma gondii pyruvate dehydrogenase complex subunit PDH-E3II 0.0034 0.0184 0.1424
Trichomonas vaginalis conserved hypothetical protein 0.0028 0.0134 0.0286
Giardia lamblia GTP-binding nuclear protein RAN/TC4 0.0021 0.0084 0.1201
Brugia malayi mucosa associated lymphoid tissue lymphoma translocation protein 1 0.0028 0.0134 0.0408

Activities

No activities found for this compound.

Phenotypes

Whole-cell/tissue/organism interactions

We have no records of whole-cell/tissue assays done with this compound What does this mean?

Many chemical entities in TDR Targets come from high-throughput screenings with whole cells or tissue samples, and not all assayed compounds have been tested against a single a single target protein, probably because they get ruled out during screening process. Even if these compounds may have not been of interest in the original screening, they may come as interesting leads for other screening assays. Furthermore, we may be able to propose drug-target associations using chemical similarities and network patterns.

Annotated phenotypes:

We have no manually annotated phenotypes for this drug. What does this mean? / Care to help?
In TDR Targets, information about phenotypes that are caused by drugs, or by genetic manipulation of cells (e.g. gene knockouts or knockdowns) is manually curated from the literature. These descriptions help to describe the potential of the target for drug development. If no information is available for this gene or if the information is incomplete, this may mean that i) the papers containing this information either appeared after the curation effort for this organism was carried out or they were inadvertently missed by curators; or that ii) the curation effort for this organism has not yet started.
 
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External resources for this compound

Bibliographic References

No literature references available for this target.

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