Detailed information for compound 1164185

Basic information

Technical information
  • Name: Unnamed compound
  • MW: 539.668 | Formula: C32H37N5O3
  • H donors: 4 H acceptors: 3 LogP: 3.85 Rotable bonds: 16
    Rule of 5 violations (Lipinski): 2
  • SMILES: NCCCCC(C(=O)N[C@@H](C(=O)N(Cc1ccccc1)C)Cc1ccccc1)NC(=O)c1c[nH]c2c1cccc2
  • InChi: 1S/C32H37N5O3/c1-37(22-24-14-6-3-7-15-24)32(40)29(20-23-12-4-2-5-13-23)36-31(39)28(18-10-11-19-33)35-30(38)26-21-34-27-17-9-8-16-25(26)27/h2-9,12-17,21,28-29,34H,10-11,18-20,22,33H2,1H3,(H,35,38)(H,36,39)/t28?,29-/m1/s1
  • InChiKey: HTGHVTIDYUULFH-YPJJGMIRSA-N  


Substructure search Similarity search

Network

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Synonyms

No synonyms found for this compound

Targets

Known targets for this compound

No curated genes were found associated with this compound

Predicted pathogen targets for this compound

By orthology
No druggable targets predicted by orthology data
By sequence similarity to non orthologous known druggable targets
No druggable targets predicted by sequence similarity
Obtained from network model

Ranking Plot

Putative Targets List

Species Potential target Raw Global Species
Echinococcus granulosus mothers against decapentaplegic 2 0.0061 0.004 0.004
Echinococcus multilocularis CAAX prenyl protease 2 0.0092 0.0073 0.0073
Echinococcus multilocularis retinoic acid receptor rxr beta a retinoic acid receptor rxr alpha a retinoic acid receptor rxr alpha 0.0025 0.0002 0.0002
Trypanosoma cruzi phosphatidylinositol 3-kinase, putative 0.1538 0.1594 0.1893
Schistosoma mansoni histone-lysine n-methyltransferase setb1 0.0224 0.0212 0.0212
Loa Loa (eye worm) phosphatidylinositol 4-kinase type 3 alpha isoform 1 0.0551 0.0556 0.066
Brugia malayi Nuclear hormone receptor family member nhr-1 0.0053 0.0032 0.0036
Echinococcus granulosus dna polymerase eta 0.0147 0.0131 0.0131
Loa Loa (eye worm) hypothetical protein 0.0132 0.0115 0.0136
Schistosoma mansoni photoreceptor-specific nuclear receptor related 0.0053 0.0032 0.0032
Loa Loa (eye worm) hypothetical protein 0.0053 0.0032 0.0036
Echinococcus multilocularis cadherin EGF LAG seven pass G type receptor 0.0257 0.0246 0.0246
Trichomonas vaginalis conserved hypothetical protein 0.0033 0.0011 0.0012
Toxoplasma gondii phosphatidylinositol 3- and 4-kinase 0.0529 0.0533 0.0849
Brugia malayi beta-lactamase family protein 0.0072 0.0052 0.0061
Onchocerca volvulus Protein ultraspiracle homolog 0.0053 0.0032 0.0167
Echinococcus granulosus chromobox protein 1 0.0072 0.0052 0.0052
Loa Loa (eye worm) nuclear hormone receptor-like 1 0.0028 0.0006 0.0005
Onchocerca volvulus 0.0095 0.0076 0.0409
Echinococcus granulosus FKBP12 rapamycin complex associated protein 0.802 0.8414 0.8414
Trypanosoma brucei dihydrolipoamide dehydrogenase 0.0089 0.007 0.0081
Brugia malayi Inositol-1 0.0228 0.0216 0.0256
Schistosoma mansoni subfamily S1A unassigned peptidase (S01 family) 0.0095 0.0076 0.0076
Echinococcus granulosus PIK kinase FAT and Armadillo domain containing protein 0.1184 0.1221 0.1221
Trichomonas vaginalis Importin beta-1 subunit, putative 0.0024 0.0002 0.0001
Trichomonas vaginalis PIKK family atypical protein kinase 0.0529 0.0533 0.0632
Echinococcus multilocularis serine protein kinase ATM 0.1538 0.1594 0.1594
Loa Loa (eye worm) voltage and ligand gated potassium channel 0.0156 0.014 0.0166
Schistosoma mansoni glutamate synthase 0.0024 0.0001 0.0001
Loa Loa (eye worm) hypothetical protein 0.0257 0.0246 0.0292
Entamoeba histolytica ubiquitin carboxyl-terminal hydrolase domain containing protein 0.0127 0.011 0.013
Echinococcus granulosus ubiquitin carboxyl terminal hydrolase 8 0.0127 0.011 0.011
Brugia malayi nuclear receptor subfamily 1, group D, member 1, putative 0.0025 0.0002 0.0002
Trichomonas vaginalis PIKK family atypical protein kinase 0.5977 0.6264 0.7445
Schistosoma mansoni retinoid-x-receptor (RXR) 0.0053 0.0032 0.0032
Entamoeba histolytica acyl-CoA synthetase, putative 0.0048 0.0027 0.003
Echinococcus granulosus mothers against decapentaplegic 5 0.0135 0.0119 0.0119
Giardia lamblia 70 kDa peptidylprolyl isomerase, putative 0.0114 0.0097 0.0114
Entamoeba histolytica peptidyl-prolyl cis-trans isomerase, FKBP-type , putative 0.0114 0.0097 0.0114
Trichomonas vaginalis rotamase, putative 0.0032 0.001 0.0011
Mycobacterium tuberculosis Probable lipase LipD 0.0072 0.0052 0.0774
Loa Loa (eye worm) ImpB/MucB/SamB family protein 0.0121 0.0104 0.0122
Schistosoma mansoni phosphatidylinositol-45-bisphosphate 3-kinase catalytic subunit alpha PI3K 0.0597 0.0604 0.0604
Trichomonas vaginalis AGC family protein kinase 0.0065 0.0045 0.0052
Echinococcus multilocularis fk506 binding protein 0.0114 0.0097 0.0097
Loa Loa (eye worm) MH1 domain-containing protein 0.0135 0.0119 0.014
Echinococcus granulosus mothers against decapentaplegic 6 0.0061 0.004 0.004
Loa Loa (eye worm) hypothetical protein 0.0106 0.0088 0.0103
Echinococcus multilocularis dihydropyrimidine dehydrogenase (NADP+) 0.0024 0.0001 0.0001
Schistosoma mansoni glutamate synthase 0.0024 0.0001 0.0001
Schistosoma mansoni retinoid-x-receptor (RXR) 0.0028 0.0006 0.0006
Echinococcus granulosus peptidyl prolyl cis trans isomerase FKBP4 0.0099 0.008 0.008
Echinococcus multilocularis Ataxin 2, N terminal,domain containing protein 0.0057 0.0036 0.0036
Mycobacterium leprae PROBABLE FATTY-ACID-CoA LIGASE FADD7 (FATTY-ACID-CoA SYNTHETASE) (FATTY-ACID-CoA SYNTHASE) 0.0048 0.0027 0.0388
Trypanosoma brucei unspecified product 0.0084 0.0064 0.0075
Plasmodium vivax ATP-dependent Clp protease proteolytic subunit, putative 0.0309 0.0302 0.5417
Trichomonas vaginalis glutaminase, putative 0.4869 0.5099 0.6059
Mycobacterium ulcerans glutaminase 0.4869 0.5099 1
Onchocerca volvulus 0.0072 0.0052 0.0277
Toxoplasma gondii non-specific serine/threonine protein kinase 0.1713 0.1778 0.2837
Trichomonas vaginalis PIKK family atypical protein kinase 0.4346 0.4548 0.5405
Entamoeba histolytica peptidyl-prolyl cis-trans isomerase, putative 0.0032 0.001 0.0011
Trypanosoma cruzi hypothetical protein, conserved 0.0038 0.0016 0.0018
Brugia malayi cytoplasmic intermediate filament protein 0.0118 0.01 0.0118
Trichomonas vaginalis PIKK family atypical protein kinase 0.1538 0.1594 0.1893
Trichomonas vaginalis Importin beta-1 subunit, putative 0.0024 0.0002 0.0001
Schistosoma mansoni chromobox protein 0.0072 0.0052 0.0052
Trichomonas vaginalis PIKK family atypical protein kinase 0.5977 0.6264 0.7445
Echinococcus multilocularis protein dispatched 1 0.0149 0.0133 0.0133
Plasmodium vivax SET domain protein, putative 0.0224 0.0212 0.3797
Mycobacterium ulcerans aldehyde dehydrogenase 0.0184 0.017 0.0331
Trichomonas vaginalis importin beta-1, putative 0.0024 0.0002 0.0001
Schistosoma mansoni hypothetical protein 0.0126 0.0109 0.0109
Brugia malayi orphan nuclear receptor NR2E1 0.0025 0.0002 0.0002
Trypanosoma cruzi peptidyl-prolyl cis-trans isomerase 0.0032 0.001 0.0011
Trichomonas vaginalis alpha-glucosidase, putative 0.0038 0.0016 0.0018
Schistosoma mansoni voltage-gated potassium channel 0.017 0.0156 0.0156
Giardia lamblia Phosphoinositide-3-kinase, class 3 0.0574 0.0581 0.0689
Leishmania major alpha glucosidase II subunit, putative 0.0038 0.0016 0.0018
Leishmania major DNA damage repair protein, putative 0.0038 0.0016 0.0018
Schistosoma mansoni hypothetical protein 0.0438 0.0437 0.0437
Brugia malayi MH2 domain containing protein 0.0061 0.004 0.0046
Entamoeba histolytica phosphatidylinositol 3-kinase, putative 0.07 0.0712 0.0846
Plasmodium vivax ataxin-2 like protein, putative 0.0128 0.0111 0.1973
Mycobacterium tuberculosis Bacterioferritin BfrB 0.0106 0.0087 0.1314
Mycobacterium ulcerans long-chain-fatty-acid--CoA ligase 0.0048 0.0027 0.005
Mycobacterium tuberculosis Probable soluble pyridine nucleotide transhydrogenase SthA (STH) (NAD(P)(+) transhydrogenase [B-specific]) (nicotinamide nucleot 0.0089 0.007 0.1042
Mycobacterium ulcerans short-chain type dehydrogenase/reductase 0.0058 0.0037 0.0071
Echinococcus multilocularis peptidyl prolyl cis trans isomerase FKBP4 0.0099 0.008 0.008
Mycobacterium ulcerans esterase/lipase LipP 0.0072 0.0052 0.01
Echinococcus granulosus importin subunit beta 1 0.003 0.0008 0.0008
Mycobacterium leprae PROBABLE FATTY-ACID-CoA LIGASE FADD2 (FATTY-ACID-CoA SYNTHETASE) (FATTY-ACID-CoA SYNTHASE) 0.0048 0.0027 0.0388
Onchocerca volvulus 0.0236 0.0224 0.1216
Mycobacterium ulcerans FK-506 binding protein, peptidyl-prolyl cis-trans isomerase 0.0114 0.0097 0.0188
Echinococcus multilocularis musashi 0.022 0.0208 0.0208
Echinococcus multilocularis sodium:potassium dependent atpase beta subunit 0.004 0.0019 0.0019
Echinococcus multilocularis peptidase Clp (S14 family) 0.0203 0.019 0.019
Trypanosoma cruzi Phosphatidylinositol 3-kinase tor2 0.802 0.8414 1
Trichomonas vaginalis conserved hypothetical protein 0.0029 0.0006 0.0006
Plasmodium vivax dihydrolipoyl dehydrogenase, mitochondrial, putative 0.0089 0.007 0.1234
Loa Loa (eye worm) nuclear hormone receptor family member nhr-49 0.0053 0.0032 0.0036
Echinococcus multilocularis dnaJ subfamily B 0.0826 0.0845 0.0845
Loa Loa (eye worm) hypothetical protein 0.0149 0.0133 0.0157
Echinococcus granulosus smad 0.0135 0.0119 0.0119
Schistosoma mansoni family S12 unassigned peptidase (S12 family) 0.0072 0.0052 0.0052
Brugia malayi Latrophilin receptor protein 2 0.0257 0.0246 0.0292
Trypanosoma brucei DNA polymerase kappa, putative 0.0121 0.0104 0.0122
Brugia malayi Phosphatidylinositol 3- and 4-kinase family protein 0.0529 0.0533 0.0632
Loa Loa (eye worm) FKBP5 protein 0.0114 0.0097 0.0114
Wolbachia endosymbiont of Brugia malayi ATP-dependent Clp protease proteolytic subunit 0.0309 0.0302 1
Trypanosoma brucei DNA polymerase eta, putative 0.0147 0.0131 0.0154
Treponema pallidum ATP-dependent Clp protease proteolytic subunit 0.0107 0.0088 0.2905
Trichomonas vaginalis sucrase-isomaltase, putative 0.0038 0.0016 0.0018
Loa Loa (eye worm) hypothetical protein 0.0025 0.0002 0.0002
Brugia malayi AMP-binding enzyme family protein 0.0048 0.0027 0.003
Schistosoma mansoni immunophilin 0.0099 0.008 0.008
Mycobacterium ulcerans long-chain-fatty-acid-CoA ligase 0.0048 0.0027 0.005
Echinococcus granulosus FTZ F1 alpha 0.0053 0.0032 0.0032
Schistosoma mansoni hypothetical protein 0.0126 0.0109 0.0109
Echinococcus granulosus peptidyl prolyl cis trans isomerase FKBP1A 0.0114 0.0097 0.0097
Loa Loa (eye worm) hypothetical protein 0.0038 0.0016 0.0018
Entamoeba histolytica hypothetical protein 0.0438 0.0437 0.0518
Loa Loa (eye worm) 3-hydroxyacyl-CoA dehydrogenase type II 0.0054 0.0033 0.0038
Mycobacterium ulcerans fusion of enoyl-CoA hydratase, EchA21 and lipase, LipE 0.0072 0.0052 0.01
Trypanosoma cruzi phosphatidylinositol 3-kinase vps34-like 0.0597 0.0604 0.0717
Loa Loa (eye worm) CXXC zinc finger family protein 0.0058 0.0037 0.0043
Entamoeba histolytica peptidyl-prolyl cis-trans isomerase, FKBP-type, putative 0.0114 0.0097 0.0114
Brugia malayi follicle stimulating hormone receptor 0.0237 0.0225 0.0266
Mycobacterium ulcerans aldehyde dehydrogenase 0.0184 0.017 0.0331
Schistosoma mansoni hypothetical protein 0.0126 0.0109 0.0109
Echinococcus multilocularis Glutaredoxin protein 5 0.004 0.0019 0.0019
Trichomonas vaginalis PIKK family atypical protein kinase 0.538 0.5636 0.6699
Trypanosoma cruzi dihydrolipoamide dehydrogenase, putative 0.0089 0.007 0.0081
Echinococcus granulosus dihydropyrimidine dehydrogenase NADP 0.0024 0.0001 0.0001
Trichomonas vaginalis PIKK family atypical protein kinase 0.0529 0.0533 0.0632
Loa Loa (eye worm) hypothetical protein 0.0102 0.0084 0.0098
Trichomonas vaginalis conserved hypothetical protein 0.1009 0.1037 0.1232
Schistosoma mansoni inositol monophosphatase 0.0228 0.0216 0.0216
Entamoeba histolytica CAAX prenyl protease family 0.0092 0.0073 0.0086
Schistosoma mansoni hypothetical protein 0.0257 0.0246 0.0246
Brugia malayi ecdysteroid receptor 0.0053 0.0032 0.0036
Onchocerca volvulus Heterochromatin protein 1 homolog 0.004 0.0019 0.0097
Toxoplasma gondii phosphatidylinositol 3- and 4-kinase 0.0529 0.0533 0.0849
Trichomonas vaginalis alpha-glucosidase, putative 0.0038 0.0016 0.0018
Trypanosoma cruzi DNA polymerase kappa, putative 0.0121 0.0104 0.0122
Echinococcus granulosus potassium:sodium hyperpolarization activated 0.0031 0.0009 0.0009
Leishmania major phosphatidylinositol 4-kinase alpha, putative 0.0551 0.0556 0.066
Trypanosoma brucei DNA polymerase kappa, putative 0.0121 0.0104 0.0122
Wolbachia endosymbiont of Brugia malayi dihydrolipoamide dehydrogenase E3 component 0.0089 0.007 0.2279
Echinococcus multilocularis FTZ F1 nuclear receptor protein 0.0053 0.0032 0.0032
Treponema pallidum bacterioferrin (TpF1) 0.0106 0.0087 0.2875
Schistosoma mansoni serine/threonine-protein kinase 0.0045 0.0023 0.0023
Brugia malayi Pyridine nucleotide-disulphide oxidoreductase, dimerisation domain containing protein 0.0065 0.0045 0.0052
Brugia malayi Nuclear hormone receptor family member nhr-31 0.0053 0.0032 0.0036
Echinococcus multilocularis sterol regulatory element binding protein 0.0131 0.0114 0.0114
Entamoeba histolytica FKBP-rapamycin associated protein (FRAP), putative 0.802 0.8414 1
Echinococcus granulosus Basic leucine zipper bZIP transcription 0.0438 0.0437 0.0437
Schistosoma mansoni alpha-glucosidase 0.0146 0.0129 0.0129
Trichomonas vaginalis voltage and ligand gated potassium channel, putative 0.0031 0.0009 0.0009
Loa Loa (eye worm) hypothetical protein 0.0309 0.0302 0.0358
Loa Loa (eye worm) hypothetical protein 0.0128 0.0111 0.013
Mycobacterium tuberculosis Probable chain -fatty-acid-CoA ligase FadD13 (fatty-acyl-CoA synthetase) 0.0048 0.0027 0.0388
Toxoplasma gondii histone lysine methyltransferase SET/SUV39 0.0224 0.0212 0.0337
Trypanosoma brucei trypanothione reductase 0.0256 0.0246 0.0291
Plasmodium vivax phosphatidylinositol 4-kinase, putative 0.0529 0.0533 0.9575
Trypanosoma brucei inositol-1(or 4)-monophosphatase 1, putative 0.0228 0.0216 0.0256
Schistosoma mansoni nuclear hormone receptor superfamily protein-related 0.0025 0.0002 0.0002
Brugia malayi hypothetical protein 0.0082 0.0063 0.0074
Loa Loa (eye worm) hypothetical protein 0.022 0.0208 0.0246
Onchocerca volvulus Huntingtin homolog 0.0132 0.0115 0.0622
Schistosoma mansoni voltage-gated potassium channel 0.0045 0.0024 0.0024
Echinococcus granulosus Niemann Pick C1 protein 0.0305 0.0297 0.0297
Loa Loa (eye worm) hypothetical protein 0.0048 0.0027 0.003
Trypanosoma cruzi DNA polymerase beta thumb, putative 0.0042 0.002 0.0023
Loa Loa (eye worm) hypothetical protein 0.0036 0.0014 0.0015
Trypanosoma brucei chrX additional, unordered contigs 0.0038 0.0016 0.0018
Schistosoma mansoni fkbp-rapamycin associated protein 0.1538 0.1594 0.1594
Plasmodium falciparum glutathione reductase 0.0256 0.0246 0.4404
Echinococcus granulosus ubiquitin specific protease 41 0.0127 0.011 0.011
Echinococcus granulosus ferritin 0.0106 0.0087 0.0087
Trypanosoma brucei DNA polymerase kappa, putative 0.0038 0.0016 0.0018
Schistosoma mansoni smad1 5 8 and 0.0135 0.0119 0.0119
Trichomonas vaginalis PIKK family atypical protein kinase 0.4764 0.4988 0.5928
Trypanosoma cruzi dihydrolipoamide dehydrogenase, putative 0.0089 0.007 0.0081
Trichomonas vaginalis conserved hypothetical protein 0.004 0.0019 0.0021
Onchocerca volvulus 0.076 0.0775 0.4219
Echinococcus granulosus Ataxin 2 N terminaldomain containing protein 0.0057 0.0036 0.0036
Loa Loa (eye worm) hypothetical protein 0.003 0.0008 0.0008
Schistosoma mansoni hypothetical protein 0.0272 0.0262 0.0262
Schistosoma mansoni cpg binding protein 0.0061 0.0041 0.0041
Giardia lamblia DINP protein human, muc B family 0.0121 0.0104 0.0122
Trichomonas vaginalis PIKK family atypical protein kinase 0.4794 0.5019 0.5965
Echinococcus multilocularis voltage gated potassium channel 0.0045 0.0024 0.0024
Echinococcus multilocularis mothers against decapentaplegic 5 0.0135 0.0119 0.0119
Mycobacterium leprae PROBABLE ATP-DEPENDENT CLP PROTEASE PROTEOLYTIC SUBUNIT 1 CLPP1 (ENDOPEPTIDASE CLP) 0.0203 0.019 0.2866
Plasmodium vivax dihydrolipoyl dehydrogenase, apicoplast, putative 0.0089 0.007 0.1234
Schistosoma mansoni hypothetical protein 0.0257 0.0246 0.0246
Brugia malayi Phosphatidylinositol 3- and 4-kinase family protein 0.2779 0.2899 0.3445
Echinococcus granulosus hepatocyte nuclear factor 4 alpha 0.0053 0.0032 0.0032
Echinococcus multilocularis hepatocyte nuclear factor 4 alpha 0.0053 0.0032 0.0032
Trypanosoma brucei dihydrolipoyl dehydrogenase 0.0089 0.007 0.0081
Plasmodium falciparum acyl-CoA synthetase 0.0036 0.0014 0.0231
Entamoeba histolytica hypothetical protein 0.0438 0.0437 0.0518
Trichomonas vaginalis PIKK family atypical protein kinase 0.4794 0.5019 0.5965
Trypanosoma brucei DNA polymerase kappa, putative 0.0121 0.0104 0.0122
Brugia malayi nuclear receptor NHR-88 0.0025 0.0002 0.0002
Trichomonas vaginalis voltage and ligand gated potassium channel, putative 0.0146 0.013 0.0153
Onchocerca volvulus Nuclear receptor subfamily 6 group A member 1 homolog 0.0025 0.0002 0.0008
Mycobacterium tuberculosis Probable NADH dehydrogenase Ndh 0.0584 0.0591 0.8958
Loa Loa (eye worm) intermediate filament tail domain-containing protein 0.022 0.0208 0.0246
Echinococcus granulosus ATP dependent Clp protease proteolytic subunit 0.0309 0.0302 0.0302
Loa Loa (eye worm) hypothetical protein 0.0072 0.0052 0.0061
Mycobacterium ulcerans acyl-CoA synthetase 0.0048 0.0027 0.005
Echinococcus multilocularis nuclear receptor subfamily 1 group D 0.0028 0.0006 0.0006
Brugia malayi Voltage-gated potassium channel, HERG (KCNH2)-related. C. elegans unc-103 ortholog 0.0156 0.014 0.0166
Leishmania major mitochondrial DNA polymerase beta 0.0299 0.029 0.0344
Plasmodium vivax hypothetical protein, conserved 0.0529 0.0533 0.9575
Schistosoma mansoni ferritin 0.0106 0.0087 0.0087
Loa Loa (eye worm) hypothetical protein 0.0132 0.0115 0.0136
Echinococcus multilocularis chromobox protein 1 0.0072 0.0052 0.0052
Plasmodium vivax phosphatidylinositol 3- and 4-kinase, putative 0.0529 0.0533 0.9575
Brugia malayi Pin1-type peptidyl-prolyl cis-trans isomerase, BmPin1 0.0033 0.0011 0.0012
Trichomonas vaginalis chromodomain helicase DNA binding protein, putative 0.0025 0.0002 0.0002
Schistosoma mansoni lamin 0.022 0.0208 0.0208
Schistosoma mansoni thyroid hormone receptor 0.0324 0.0317 0.0317
Echinococcus granulosus retinoic acid receptor rxr beta a 0.0053 0.0032 0.0032
Trypanosoma brucei target of rapamycin kinase 3, putative 0.6396 0.6704 0.7968
Leishmania major hypothetical protein, unknown function 0.0529 0.0533 0.0632
Echinococcus granulosus Glutaredoxin protein 5 0.004 0.0019 0.0019
Brugia malayi glutaminase DH11.1 0.4869 0.5099 0.6059
Trichomonas vaginalis PIKK family atypical protein kinase 0.2721 0.2839 0.3374
Trichomonas vaginalis conserved hypothetical protein 0.1184 0.1221 0.1451
Plasmodium vivax importin-beta 2, putative 0.003 0.0008 0.0121
Giardia lamblia Hypothetical protein 0.0092 0.0073 0.0086
Trypanosoma brucei mitochondrial DNA polymerase beta 0.0299 0.029 0.0344
Echinococcus multilocularis nervana 2 0.004 0.0019 0.0019
Plasmodium falciparum ataxin-2 like protein, putative 0.0128 0.0111 0.1973
Trichomonas vaginalis chromobox protein, putative 0.0072 0.0052 0.0061
Trichomonas vaginalis PIKK family atypical protein kinase 0.802 0.8414 1
Brugia malayi Phosphatidylinositol 3- and 4-kinase family protein 0.0667 0.0678 0.0804
Loa Loa (eye worm) hypothetical protein 0.0135 0.0119 0.014
Onchocerca volvulus 0.022 0.0208 0.1126
Entamoeba histolytica phosphatidylinositol 3-kinase, putative 0.0745 0.076 0.0903
Schistosoma mansoni sulfide quinone reductase 0.0024 0.0001 0.0001
Schistosoma mansoni Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) 0.0328 0.0321 0.0321
Loa Loa (eye worm) GTP-binding regulatory protein Gs alpha-S chain 0.0328 0.0321 0.0381
Trypanosoma cruzi phosphatidylinositol kinase related protein, putative 0.1009 0.1037 0.1232
Trypanosoma brucei PAB1-binding protein , putative 0.0128 0.0111 0.013
Entamoeba histolytica protein kinase rad3, putative 0.1538 0.1594 0.1893
Loa Loa (eye worm) phosphatidylinositol 3 0.2734 0.2852 0.3389
Giardia lamblia FKBP-type peptidyl-prolyl cis-trans isomerase 0.0114 0.0097 0.0114
Schistosoma mansoni hypothetical protein 0.0353 0.0347 0.0347
Schistosoma mansoni ecdysone-induced protein 78c (dr-78) 0.0028 0.0006 0.0006
Brugia malayi MH1 domain containing protein 0.0135 0.0119 0.014
Trichomonas vaginalis AGC family protein kinase 0.0065 0.0045 0.0052
Brugia malayi Pre-SET motif family protein 0.0224 0.0212 0.0251
Trypanosoma brucei rac serine-threonine kinase, putative 0.0065 0.0045 0.0052
Brugia malayi Nuclear hormone receptor family member nhr-19 0.0053 0.0032 0.0036
Trypanosoma cruzi importin beta-1 subunit, putative 0.0024 0.0002 0.0001
Echinococcus granulosus guanine nucleotide binding protein Gs subunit 0.0328 0.0321 0.0321
Brugia malayi Nuclear hormone receptor family member nhr-40 0.0053 0.0032 0.0036
Loa Loa (eye worm) hypothetical protein 0.0025 0.0002 0.0002
Schistosoma mansoni smad 0.0061 0.004 0.004
Entamoeba histolytica acyl-CoA synthetase, putative 0.0048 0.0027 0.003
Trypanosoma cruzi hypothetical protein, conserved 0.0038 0.0016 0.0018
Entamoeba histolytica hypothetical protein 0.0529 0.0533 0.0632
Loa Loa (eye worm) hypothetical protein 0.0072 0.0052 0.0061
Trichomonas vaginalis PIKK family atypical protein kinase 0.2734 0.2852 0.3389
Loa Loa (eye worm) hypothetical protein 0.0095 0.0076 0.0089
Brugia malayi CHE-14 protein 0.0131 0.0114 0.0134
Mycobacterium leprae conserved hypothetical protein 0.0529 0.0533 0.8079
Echinococcus granulosus TGF beta signal transducer SmadC 0.0135 0.0119 0.0119
Trypanosoma cruzi Protein kinase B 0.0045 0.0023 0.0027
Entamoeba histolytica phosphatidylinositol 3-kinase, putative 0.0597 0.0604 0.0717
Brugia malayi nuclear receptor NHR-88 0.0053 0.0032 0.0036
Loa Loa (eye worm) hypothetical protein 0.0053 0.0032 0.0036
Echinococcus multilocularis beta LACTamase domain containing family member 0.0072 0.0052 0.0052
Loa Loa (eye worm) inositol-1 0.0228 0.0216 0.0256
Trichomonas vaginalis PIKK family atypical protein kinase 0.5205 0.5452 0.648
Brugia malayi Phosphatidylinositol 3- and 4-kinase family protein 0.1538 0.1594 0.1893
Echinococcus multilocularis dihydropyrimidine dehydrogenase (NADP+) 0.0024 0.0001 0.0001
Loa Loa (eye worm) hypothetical protein 0.0025 0.0002 0.0002
Entamoeba histolytica phosphatidylinositol 3-kinase 3, putative 0.0529 0.0533 0.0632
Loa Loa (eye worm) hypothetical protein 0.0812 0.083 0.0985
Echinococcus multilocularis cyclic nucleotide gated cation channel 0.0031 0.0009 0.0009
Trypanosoma cruzi DNA polymerase kappa, putative 0.0121 0.0104 0.0122
Echinococcus granulosus Phosphatidylinositol 4 kinase type 2 beta 0.0529 0.0533 0.0533
Loa Loa (eye worm) phosphatidylinositol 3 0.0529 0.0533 0.0632
Trichomonas vaginalis PIKK family atypical protein kinase 0.802 0.8414 1
Echinococcus granulosus nuclear receptor 2DBD gamma 0.0053 0.0032 0.0032
Loa Loa (eye worm) nuclear hormone receptor 0.0025 0.0002 0.0002
Wolbachia endosymbiont of Brugia malayi dihydrolipoamide dehydrogenase E3 component 0.0089 0.007 0.2279
Loa Loa (eye worm) nuclear hormone receptor family member nhr-41 0.0053 0.0032 0.0036
Onchocerca volvulus 0.0032 0.001 0.0047
Leishmania major phosphatidylinositol 3-kinase, putative 0.0551 0.0556 0.066
Schistosoma mansoni alpha-glucosidase 0.0146 0.0129 0.0129
Onchocerca volvulus Bile acid receptor homolog 0.0053 0.0032 0.0167
Trichomonas vaginalis PIKK family atypical protein kinase 0.5977 0.6264 0.7445
Leishmania major phosphatidylinositol 4-kinase, putative 0.0529 0.0533 0.0632
Mycobacterium tuberculosis Probable short-chain type dehydrogenase/reductase 0.0058 0.0037 0.0547
Brugia malayi nuclear hormone receptor family member nhr-6 0.0025 0.0002 0.0002
Echinococcus granulosus glutamate synthase 0.0024 0.0001 0.0001
Loa Loa (eye worm) hypothetical protein 0.0025 0.0002 0.0002
Trichomonas vaginalis chromobox protein, putative 0.0043 0.0022 0.0025
Echinococcus granulosus potassium voltage gated channel subfamily H 0.0156 0.014 0.014
Echinococcus granulosus nervana 2 0.004 0.0019 0.0019
Schistosoma mansoni ataxia telangiectasia mutated (atm)-related 0.802 0.8414 0.8414
Trypanosoma brucei hypothetical protein, conserved 0.0072 0.0052 0.0061
Echinococcus granulosus nuclear receptor subfamily 4 group A 0.0025 0.0002 0.0002
Echinococcus granulosus sulfide:quinone oxidoreductase 0.0024 0.0001 0.0001
Brugia malayi FAT domain containing protein 0.1184 0.1221 0.1451
Trypanosoma cruzi ubiquitin carboxyl-terminal hydrolase, putative 0.0127 0.011 0.013
Loa Loa (eye worm) nuclear receptor nhr-7B 0.0025 0.0002 0.0002
Brugia malayi phosphatidylinositol 4-kinase, catalytic, alpha polypeptide 0.0551 0.0556 0.066
Loa Loa (eye worm) hypothetical protein 0.004 0.0019 0.0021
Leishmania major phosphatidylinositol 3-kinase, putative 0.2721 0.2839 0.3374
Leishmania major phosphatidylinositol 3-related kinase, putative 0.2734 0.2852 0.3389
Chlamydia trachomatis ATP-dependent Clp protease proteolytic subunit 0.0309 0.0302 1
Loa Loa (eye worm) AGC/AKT protein kinase 0.0065 0.0045 0.0052
Plasmodium vivax 70 kDa peptidylprolyl isomerase, putative 0.0114 0.0097 0.1722
Brugia malayi hypothetical protein 0.0128 0.0111 0.013
Mycobacterium tuberculosis Probable esterase LipL 0.0072 0.0052 0.0774
Trypanosoma brucei phosphatidylinositol 3-related kinase, putative 0.2734 0.2852 0.3389
Trypanosoma cruzi dihydrolipoamide dehydrogenase, putative 0.0089 0.007 0.0081
Trichomonas vaginalis esterase, putative 0.0072 0.0052 0.0061
Echinococcus granulosus cyclic nucleotide gated cation channel alpha 3 0.0031 0.0009 0.0009
Treponema pallidum NADH oxidase 0.0089 0.007 0.2279
Trypanosoma cruzi rac serine-threonine kinase, putative 0.0041 0.0019 0.0022
Brugia malayi Niemann-Pick C1 protein precursor 0.0305 0.0297 0.0352
Brugia malayi Nuclear hormone receptor-like 1 0.0053 0.0032 0.0036
Loa Loa (eye worm) Smad1 0.0135 0.0119 0.014
Trichomonas vaginalis PIKK family atypical protein kinase 0.6389 0.6698 0.796
Mycobacterium tuberculosis NAD(P)H quinone reductase LpdA 0.0649 0.0659 1
Trypanosoma cruzi phosphatidylinositol 4-kinase alpha, putative 0.0551 0.0556 0.066
Schistosoma mansoni 60S ribosomal protein L21 0.0025 0.0002 0.0002
Mycobacterium tuberculosis Conserved protein 0.0072 0.0052 0.0774
Trypanosoma brucei DNA polymerase kappa, putative 0.0121 0.0104 0.0122
Schistosoma mansoni TGF-beta signal transducer Smad2 0.0135 0.0119 0.0119
Schistosoma mansoni family U48 unassigned peptidase (U48 family) 0.0092 0.0073 0.0073
Mycobacterium tuberculosis Conserved protein 0.0072 0.0052 0.0774
Trichomonas vaginalis phosphatidylinositol kinase, putative 0.0597 0.0604 0.0717
Brugia malayi MH1 domain containing protein 0.0075 0.0055 0.0064
Schistosoma mansoni hypothetical protein 0.0024 0.0001 0.0001
Brugia malayi hypothetical protein 0.0438 0.0437 0.0518
Echinococcus granulosus cytoplasmic intermediate filament protein 0.0106 0.0088 0.0088
Brugia malayi hypothetical protein 0.0025 0.0002 0.0002
Loa Loa (eye worm) cytoplasmic intermediate filament protein 0.0118 0.01 0.0118
Schistosoma mansoni ferritin light chain 0.0106 0.0087 0.0087
Schistosoma mansoni niemann-pick C1 (NPC1) 0.0309 0.0302 0.0302
Echinococcus granulosus intermediate filament protein 0.022 0.0208 0.0208
Trypanosoma cruzi myo-inositol-1(or 4)-monophosphatase 1, putative 0.0228 0.0216 0.0256
Trypanosoma brucei phosphatidylinositol kinase related protein, putative 0.1538 0.1594 0.1893
Loa Loa (eye worm) hypothetical protein 0.0224 0.0212 0.0251
Loa Loa (eye worm) hypothetical protein 0.0053 0.0032 0.0036
Brugia malayi hypothetical protein 0.0149 0.0133 0.0157
Mycobacterium ulcerans dihydrolipoamide dehydrogenase 0.0089 0.007 0.0134
Entamoeba histolytica acyl-coA synthetase, putative 0.0048 0.0027 0.003
Schistosoma mansoni immunophilin 0.0114 0.0097 0.0097
Plasmodium vivax phosphatidylinositol 3-kinase, putative 0.0551 0.0556 1
Brugia malayi mothers against decapentaplegic homolog 3 0.0061 0.004 0.0046
Chlamydia trachomatis ATP-dependent Clp protease proteolytic subunit 0.0309 0.0302 1
Trypanosoma brucei phosphatidylinositol 4-kinase alpha, putative 0.0551 0.0556 0.066
Brugia malayi Voltage-gated potassium channel, EAG (KCNH1)-related. C. elegans egl-2 ortholog 0.0045 0.0024 0.0027
Echinococcus multilocularis Smad4 0.0135 0.0119 0.0119
Mycobacterium ulcerans ATP-dependent Clp protease proteolytic subunit 0.0309 0.0302 0.059
Trypanosoma cruzi phosphatidylinositol 3-kinase, putative 0.0068 0.0048 0.0056
Mycobacterium ulcerans bacterioferritin BfrA 0.0106 0.0087 0.017
Echinococcus granulosus expressed conserved protein 0.0286 0.0277 0.0277
Trichomonas vaginalis phosphatidylinositol kinase, putative 0.0745 0.076 0.0903
Echinococcus multilocularis glutamate synthase 0.0024 0.0001 0.0001
Mycobacterium tuberculosis Probable monophosphatase 0.0024 0.0001 0.0006
Brugia malayi Pre-SET motif family protein 0.1554 0.1611 0.1914
Echinococcus granulosus phosphatidylinositol 45 bisphosphate 3 kinase 0.0942 0.0967 0.0967
Loa Loa (eye worm) phosphatidylinositol 3 0.0896 0.0919 0.1091
Trypanosoma cruzi peptidyl-prolyl cis-trans isomerase, putative 0.0114 0.0097 0.0114
Loa Loa (eye worm) phosphatidylinositol kinase 0.0529 0.0533 0.0632
Echinococcus granulosus 3'2'5' bisphosphate nucleotidase 1 0.0024 0.0001 0.0001
Plasmodium vivax DNA repair protein REV1, putative 0.0038 0.0016 0.0267
Loa Loa (eye worm) glutaminase 2 0.4869 0.5099 0.6059
Schistosoma mansoni tar DNA-binding protein 0.0386 0.0382 0.0382
Mycobacterium ulcerans acyl-CoA synthetase 0.0048 0.0027 0.005
Plasmodium falciparum thioredoxin reductase 0.0256 0.0246 0.4404
Brugia malayi Corticotropin releasing factor receptor 2 precursor, putative 0.0812 0.083 0.0985
Trichomonas vaginalis phosphatidylinositol 3-kinase class, putative 0.0597 0.0604 0.0717
Schistosoma mansoni DNA polymerase IV / kappa 0.0038 0.0016 0.0016
Trichomonas vaginalis PIKK family atypical protein kinase 0.2721 0.2839 0.3374
Plasmodium falciparum dihydrolipoyl dehydrogenase, apicoplast 0.0089 0.007 0.1234
Onchocerca volvulus 0.0048 0.0027 0.0139
Loa Loa (eye worm) TAR-binding protein 0.0386 0.0382 0.0453
Trypanosoma cruzi hypothetical protein, conserved 0.0038 0.0016 0.0018
Trichomonas vaginalis peptidylprolyl isomerase, putative 0.0114 0.0097 0.0114
Loa Loa (eye worm) glycosyl hydrolase family 31 protein 0.0038 0.0016 0.0018
Schistosoma mansoni disulfide oxidoreductase 0.0024 0.0001 0.0001
Loa Loa (eye worm) nuclear hormone receptor family member nhr-1 0.0053 0.0032 0.0036
Mycobacterium tuberculosis Probable ATP-dependent CLP protease proteolytic subunit 1 ClpP1 (endopeptidase CLP) 0.0203 0.019 0.2866
Trichomonas vaginalis rotamase, putative 0.0033 0.0011 0.0012
Toxoplasma gondii AGC kinase 0.0061 0.0041 0.0064
Mycobacterium leprae Probable lipase LipE 0.0072 0.0052 0.0774
Echinococcus granulosus beta LACTamase domain containing family member 0.0072 0.0052 0.0052
Loa Loa (eye worm) hypothetical protein 0.0032 0.001 0.001
Schistosoma mansoni tar DNA-binding protein 0.0386 0.0382 0.0382
Trypanosoma cruzi FK506-binding protein (FKBP)-type peptidyl-prolyl isomerase, putative 0.0114 0.0097 0.0114
Echinococcus multilocularis mothers against decapentaplegic 2 0.0061 0.004 0.004
Brugia malayi hypothetical protein 0.0028 0.0006 0.0005
Loa Loa (eye worm) hypothetical protein 0.0072 0.0052 0.0061
Schistosoma mansoni smad1 5 8 and 0.0135 0.0119 0.0119
Trypanosoma cruzi peptidase with unknown catalytic mechanism (family U48) 0.0092 0.0073 0.0086
Echinococcus multilocularis expressed protein 0.0033 0.0011 0.0011
Trypanosoma brucei FAT domain/Rapamycin binding domain/Phosphatidylinositol 3- and 4-kinase, putative 0.3344 0.3494 0.4152
Trypanosoma cruzi PAB1-binding protein , putative 0.0128 0.0111 0.013
Loa Loa (eye worm) hypothetical protein 0.0028 0.0006 0.0005
Echinococcus granulosus tar DNA binding protein 0.0386 0.0382 0.0382
Mycobacterium tuberculosis Probable membrane NADH dehydrogenase NdhA 0.0584 0.0591 0.8958
Brugia malayi Nuclear hormone receptor family member nhr-41 0.0053 0.0032 0.0036
Toxoplasma gondii LsmAD domain-containing protein 0.0128 0.0111 0.0175
Trichomonas vaginalis AGC family protein kinase 0.0025 0.0003 0.0002
Loa Loa (eye worm) hypothetical protein 0.0072 0.0052 0.0061
Loa Loa (eye worm) hypothetical protein 0.0061 0.004 0.0046
Echinococcus multilocularis sulfide:quinone oxidoreductase 0.0024 0.0001 0.0001
Plasmodium falciparum ATP-dependent Clp protease proteolytic subunit 0.0107 0.0088 0.1574
Trichomonas vaginalis Clan CA, family C19, ubiquitin hydrolase-like cysteine peptidase 0.0127 0.011 0.013
Echinococcus multilocularis phosphatidylinositol 4,5 bisphosphate 3 kinase 0.0942 0.0967 0.0967
Trichomonas vaginalis PIKK family atypical protein kinase 0.4353 0.4555 0.5414
Brugia malayi Hypothetical 52.5 kDa protein ZK945.1 in chromosome II, putative 0.0072 0.0052 0.0061
Schistosoma mansoni phosphatidylinositol 3-and 4-kinase 0.2779 0.2899 0.2899
Mycobacterium tuberculosis Conserved hypothetical protein 0.0121 0.0104 0.1563
Loa Loa (eye worm) hypothetical protein 0.0131 0.0114 0.0134
Echinococcus multilocularis dna polymerase kappa 0.0121 0.0104 0.0104
Echinococcus multilocularis DNA dependent protein kinase catalytic subunit 0.0821 0.0839 0.0839
Leishmania major 3-oxoacyl-(acyl-carrier protein) reductase, putative 0.0058 0.0037 0.0043
Echinococcus granulosus lamin 0.022 0.0208 0.0208
Trypanosoma cruzi trypanothione reductase, putative 0.0089 0.007 0.0081
Schistosoma mansoni cyclic-nucleotide-gated cation channel 0.0031 0.0009 0.0009
Trichomonas vaginalis conserved hypothetical protein 0.0127 0.011 0.013
Schistosoma mansoni hypothetical protein 0.0024 0.0001 0.0001
Trypanosoma cruzi trypanothione reductase, putative 0.0256 0.0246 0.0291
Schistosoma mansoni tar DNA-binding protein 0.0386 0.0382 0.0382
Brugia malayi phosphoinositide 3'-hydroxykinase p110-alpha subunit, putative 0.0196 0.0183 0.0216
Trypanosoma cruzi hypothetical protein, conserved 0.0038 0.0016 0.0018
Echinococcus multilocularis 3 hydroxyacyl coenzyme A dehydrogenase type 2 0.0058 0.0037 0.0037
Toxoplasma gondii thioredoxin reductase 0.0256 0.0246 0.039
Loa Loa (eye worm) hypothetical protein 0.0099 0.008 0.0094
Brugia malayi Ubiquitin carboxyl-terminal hydrolase family protein 0.0127 0.011 0.013
Echinococcus granulosus Nuclear hormone receptor HR96 0.0025 0.0002 0.0002
Schistosoma mansoni nuclear hormone receptor 0.0025 0.0002 0.0002
Loa Loa (eye worm) RNA binding protein 0.0386 0.0382 0.0453
Echinococcus granulosus hyperpolarization activated cyclic 0.0031 0.0009 0.0009
Mycobacterium ulcerans short-chain type dehydrogenase/reductase 0.0058 0.0037 0.0071
Brugia malayi RNA recognition motif domain containing protein 0.0386 0.0382 0.0453
Leishmania major 4-coumarate:coa ligase-like protein 0.0048 0.0027 0.003
Trypanosoma cruzi dihydrolipoamide dehydrogenase, putative 0.0089 0.007 0.0081
Loa Loa (eye worm) hypothetical protein 0.1625 0.1685 0.2002
Mycobacterium tuberculosis Probable aldehyde dehydrogenase 0.0184 0.017 0.2563
Echinococcus granulosus GPCR family 2 0.0257 0.0246 0.0246
Loa Loa (eye worm) hypothetical protein 0.1713 0.1778 0.2112
Schistosoma mansoni nuclear receptor 0.0025 0.0002 0.0002
Schistosoma mansoni phosphatidylinositol 4-kinase 0.0529 0.0533 0.0533
Leishmania major phosphatidylinositol kinase, putative 0.0529 0.0533 0.0632
Loa Loa (eye worm) hypothetical protein 0.0053 0.0032 0.0036
Loa Loa (eye worm) hypothetical protein 0.0072 0.0052 0.0061
Loa Loa (eye worm) nuclear hormone receptor family member nhr-31 0.0053 0.0032 0.0036
Trypanosoma brucei DNA damage repair protein, putative 0.0038 0.0016 0.0018
Loa Loa (eye worm) hypothetical protein 0.0053 0.0032 0.0036
Trypanosoma brucei DNA polymerase kappa, putative 0.0084 0.0064 0.0075
Entamoeba histolytica phosphatidylinositol 3-kinase, putative 0.0621 0.063 0.0747
Schistosoma mansoni phosphatidylinositol-45-bisphosphate 3-kinase catalytic subunit alpha PI3K 0.0942 0.0967 0.0967
Trichomonas vaginalis chromodomain helicase DNA binding protein, putative 0.0025 0.0002 0.0002
Loa Loa (eye worm) abnormal chemotaxis protein 14 0.0131 0.0114 0.0134
Entamoeba histolytica protein kinase, putative 0.0065 0.0045 0.0052
Trypanosoma brucei DNA polymerase kappa, putative 0.0084 0.0064 0.0075
Onchocerca volvulus Mothers against decapentaplegic homolog 0.0061 0.004 0.0212
Mycobacterium leprae ATP-dependent Clp protease proteolytic subunit 1 0.0107 0.0088 0.1328
Echinococcus multilocularis Nuclear hormone receptor HR96 0.0025 0.0002 0.0002
Trypanosoma brucei hypothetical protein, conserved 0.0038 0.0016 0.0018
Trypanosoma brucei unspecified product 0.0121 0.0104 0.0122
Echinococcus multilocularis FKBP12 rapamycin complex associated protein 0.802 0.8414 0.8414
Schistosoma mansoni rab geranylgeranyl transferase alpha subunit 0.0121 0.0104 0.0104
Treponema pallidum peptidyl-prolyl cis-trans isomerase, FKBP-type, 22 kDa (fklB) 0.0114 0.0097 0.3178
Schistosoma mansoni hypothetical protein 0.0529 0.0533 0.0533
Brugia malayi tailless protein 0.0025 0.0002 0.0002
Leishmania major 4-coumarate:coa ligase-like protein 0.0048 0.0027 0.003
Trypanosoma cruzi phosphatidylinositol 3-kinase 2, putative 0.0745 0.076 0.0903
Loa Loa (eye worm) pre-SET domain-containing protein family protein 0.1554 0.1611 0.1914
Trichomonas vaginalis DNA polymerase IV / kappa, putative 0.0121 0.0104 0.0122
Mycobacterium ulcerans inositol-monophosphatase ImpA 0.0024 0.0001 0.0001
Brugia malayi Nuclear hormone receptor-like 1 0.0028 0.0006 0.0005
Echinococcus granulosus chromobox protein 1 0.0072 0.0052 0.0052
Schistosoma mansoni inositol monophosphatase 0.0228 0.0216 0.0216
Giardia lamblia Phosphatidylinositol 4-kinase 0.0529 0.0533 0.0632
Mycobacterium ulcerans aldehyde dehydrogenase 0.0184 0.017 0.0331
Toxoplasma gondii ATP-dependent Clp endopeptidase, proteolytic subunit ClpP domain-containing protein 0.0309 0.0302 0.048
Trichomonas vaginalis AGC family protein kinase 0.0065 0.0045 0.0052
Plasmodium falciparum ATP-dependent Clp protease proteolytic subunit 0.0309 0.0302 0.5417
Loa Loa (eye worm) phosphatidylinositol 3 0.0529 0.0533 0.0632
Schistosoma mansoni hypothetical protein 0.032 0.0313 0.0313
Trypanosoma brucei peptidyl-prolyl cis-trans isomerase/rotamase, putative 0.0032 0.001 0.0011
Loa Loa (eye worm) hypothetical protein 0.0025 0.0002 0.0002
Echinococcus multilocularis serine threonine protein kinase nrc serine threonine protein kinase gad 0.0041 0.0019 0.0019
Trichomonas vaginalis conserved hypothetical protein 0.004 0.0019 0.0021
Brugia malayi Nuclear hormone receptor E75 0.0025 0.0002 0.0002
Echinococcus multilocularis microtubule associated protein 2 0.9528 1 1
Echinococcus granulosus NADPH:adrenodoxin oxidoreductase 0.0024 0.0001 0.0001
Echinococcus multilocularis terminal deoxycytidyl transferase rev1 0.0121 0.0104 0.0104
Leishmania major hypothetical protein, conserved 0.0128 0.0111 0.013
Echinococcus granulosus phosphatidylinositol 4 phosphate 3 kinase C2 0.0667 0.0678 0.0678
Mycobacterium tuberculosis Probable bacterioferritin BfrA 0.0106 0.0087 0.1314
Mycobacterium tuberculosis Probable dehydrogenase 0.0584 0.0591 0.8958
Schistosoma mansoni family S12 unassigned peptidase (S12 family) 0.0072 0.0052 0.0052
Mycobacterium ulcerans DNA polymerase IV 0.0121 0.0104 0.0202
Trichomonas vaginalis phosphatidylinositol 4-kinase, putative 0.0551 0.0556 0.066
Entamoeba histolytica phosphatidylinositol 4-kinase, putative 0.0551 0.0556 0.066
Trypanosoma cruzi peptidyl-prolyl cis-trans isomerase, putative 0.0114 0.0097 0.0114
Schistosoma mansoni hyperpolarization activated cyclic nucleotide-gated potassium channel 0.0031 0.0009 0.0009
Toxoplasma gondii phosphatidylinositol 3- and 4-kinase 0.0551 0.0556 0.0887
Entamoeba histolytica glycosyl hydrolase, family 31 protein 0.0038 0.0016 0.0018
Echinococcus granulosus Mitotic checkpoint protein PRCC C terminal 0.0272 0.0262 0.0262
Echinococcus multilocularis phosphatidylinositol 4 phosphate 3 kinase C2 0.0667 0.0678 0.0678
Onchocerca volvulus 0.0098 0.0079 0.0426
Brugia malayi Smad1 0.0135 0.0119 0.014
Brugia malayi Ligand-binding domain of nuclear hormone receptor family protein 0.0053 0.0032 0.0036
Toxoplasma gondii NADPH-glutathione reductase 0.0089 0.007 0.0109
Schistosoma mansoni nuclear hormone receptor 0.0053 0.0032 0.0032
Trichomonas vaginalis penicillin-binding protein, putative 0.0072 0.0052 0.0061
Leishmania major trypanothione reductase 0.0256 0.0246 0.0291
Entamoeba histolytica Phosphatidylinositol 3- and 4-kinase family 0.155 0.1607 0.1909
Schistosoma mansoni alpha glucosidase 0.0038 0.0016 0.0016
Schistosoma mansoni importin beta-1 0.003 0.0008 0.0008
Schistosoma mansoni subfamily S1A unassigned peptidase (S01 family) 0.0095 0.0076 0.0076
Schistosoma mansoni hypothetical protein 0.0126 0.0109 0.0109
Brugia malayi steroid hormone receptor 0.0053 0.0032 0.0036
Echinococcus multilocularis peptidyl prolyl cis trans isomerase FKBP4 0.0114 0.0097 0.0097
Loa Loa (eye worm) DR-78 0.0025 0.0002 0.0002
Loa Loa (eye worm) hypothetical protein 0.016 0.0145 0.0171
Trichomonas vaginalis neutral alpha-glucosidase ab precursor, putative 0.0038 0.0016 0.0018
Trichomonas vaginalis Clan U, family U48, CaaX prenyl peptidase 2-like 0.0092 0.0073 0.0086
Loa Loa (eye worm) MH2 domain-containing protein 0.0061 0.004 0.0046
Echinococcus granulosus COUP TF:Svp nuclear hormone receptor 0.0053 0.0032 0.0032
Treponema pallidum ATP-dependent Clp protease proteolytic subunit 0.0309 0.0302 1
Mycobacterium tuberculosis Probable ATP-dependent CLP protease proteolytic subunit 2 ClpP2 (endopeptidase CLP 2) 0.0203 0.019 0.2866
Giardia lamblia NADH oxidase lateral transfer candidate 0.0089 0.007 0.0081
Trypanosoma brucei DNA polymerase kappa, putative 0.0038 0.0016 0.0018
Schistosoma mansoni phosphatidylinositol 4-kinase 0.0551 0.0556 0.0556
Brugia malayi beta-lactamase family protein 0.0072 0.0052 0.0061
Brugia malayi Cyclic-nucleotide gated cation channel 0.0031 0.0009 0.0009
Leishmania major hypothetical protein, conserved 0.0632 0.0641 0.0761
Leishmania major CAAX prenyl protease 2, putative,peptidase with unknown catalytic mechanism (family U48) 0.0092 0.0073 0.0086
Leishmania major target of rapamycin (TOR) kinase 2, putative 0.802 0.8414 1
Brugia malayi Phosphatidylinositol 3- and 4-kinase family protein 0.0745 0.076 0.0903
Mycobacterium leprae conserved hypothetical protein 0.0072 0.0052 0.0774
Schistosoma mansoni aldehyde dehydrogenase 0.0184 0.017 0.017
Loa Loa (eye worm) hypothetical protein 0.076 0.0775 0.0921
Schistosoma mansoni cpg binding protein 0.0058 0.0037 0.0037
Schistosoma mansoni rotamase 0.0033 0.0011 0.0011
Toxoplasma gondii aldehyde dehydrogenase 0.0184 0.017 0.0269
Brugia malayi Trypsin family protein 0.0095 0.0076 0.0089
Schistosoma mansoni ferritin 0.0106 0.0087 0.0087
Brugia malayi CXXC zinc finger family protein 0.0058 0.0037 0.0043
Trypanosoma cruzi DNA polymerase eta, putative 0.0063 0.0043 0.005
Echinococcus multilocularis phosphatidylinositol 3 and 4 kinase 0.2779 0.2899 0.2899
Trichomonas vaginalis inositol monophosphatase, putative 0.0228 0.0216 0.0256
Schistosoma mansoni thyroid hormone receptor 0.0324 0.0317 0.0317
Plasmodium falciparum peptidyl-prolyl cis-trans isomerase FKBP35 0.0114 0.0097 0.1722
Trypanosoma brucei dihydrolipoamide dehydrogenase, point mutation 0.0089 0.007 0.0081
Trichomonas vaginalis ferritin, putative 0.0106 0.0087 0.0103
Mycobacterium ulcerans bacterioferritin BfrB 0.0106 0.0087 0.017
Loa Loa (eye worm) hypothetical protein 0.0025 0.0002 0.0002
Loa Loa (eye worm) hypothetical protein 0.0127 0.011 0.013
Schistosoma mansoni steroid hormone receptor ad4bp 0.0053 0.0032 0.0032
Trichomonas vaginalis conserved hypothetical protein 0.0131 0.0114 0.0134
Toxoplasma gondii phosphatidylinositol 3- and 4-kinase 0.0551 0.0556 0.0887
Trypanosoma cruzi mitochondrial DNA polymerase beta, putative 0.0299 0.029 0.0344
Trichomonas vaginalis maltase-glucoamylase, putative 0.0038 0.0016 0.0018
Echinococcus multilocularis dihydrolipoamide dehydrogenase 0.0089 0.007 0.007
Leishmania major peptidylprolyl isomerase-like protein 0.0114 0.0097 0.0114
Loa Loa (eye worm) hypothetical protein 0.0036 0.0014 0.0015
Trichomonas vaginalis chromobox protein, putative 0.0043 0.0022 0.0025
Toxoplasma gondii peptidylprolyl isomerase 0.0032 0.001 0.0015
Trichomonas vaginalis PIKK family atypical protein kinase 0.4764 0.4988 0.5928
Trypanosoma brucei importin beta-1 subunit, putative 0.003 0.0008 0.0008
Trichomonas vaginalis DNA polymerase eta, putative 0.0121 0.0104 0.0122
Trichomonas vaginalis D-aminoacylase, putative 0.0072 0.0052 0.0061
Loa Loa (eye worm) follicle stimulating hormone receptor 0.0237 0.0225 0.0266
Toxoplasma gondii hypothetical protein 0.0107 0.0088 0.014
Onchocerca volvulus 0.0053 0.0032 0.0167
Onchocerca volvulus 0.0072 0.0052 0.0277
Toxoplasma gondii histone lysine methyltransferase SET1 0.0118 0.01 0.0159
Echinococcus multilocularis NADPH:adrenodoxin oxidoreductase 0.0024 0.0001 0.0001
Toxoplasma gondii HEAT repeat-containing protein 0.003 0.0008 0.0011
Loa Loa (eye worm) beta-lactamase 0.0072 0.0052 0.0061
Mycobacterium ulcerans fatty-acid-CoA ligase 0.0036 0.0014 0.0025
Trypanosoma cruzi phosphatidylinositol kinase related protein, putative 0.1538 0.1594 0.1893
Giardia lamblia Phosphoinositide-3-kinase, catalytic, alpha polypeptide 0.063 0.0639 0.0758
Entamoeba histolytica protein kinase 2, putative 0.0041 0.0019 0.0022
Trypanosoma cruzi ubiquitin carboxyl-terminal hydrolase, putative 0.0127 0.011 0.013
Toxoplasma gondii target of rapamycin (TOR), putative 0.5977 0.6264 1
Trichomonas vaginalis AGC family protein kinase 0.0065 0.0045 0.0052
Schistosoma mansoni glutaminase 0.4869 0.5099 0.5099
Brugia malayi RNA, U transporter 1 0.0085 0.0066 0.0077
Echinococcus multilocularis serine:threonine protein kinase SMG1 0.1538 0.1594 0.1594
Brugia malayi RNA binding protein 0.0386 0.0382 0.0453
Echinococcus multilocularis lysosomal alpha glucosidase 0.0169 0.0154 0.0154
Trichomonas vaginalis phosphatidylinositol kinase, putative 0.0529 0.0533 0.0632
Giardia lamblia Kinase, AGC PKA 0.0041 0.0019 0.0022
Echinococcus granulosus serine threonine protein kinase nrc 0.0041 0.0019 0.0019
Brugia malayi Ligand-binding domain of nuclear hormone receptor family protein 0.0053 0.0032 0.0036
Echinococcus granulosus thioredoxin glutathione reductase 0.0256 0.0246 0.0246
Echinococcus granulosus cyclic nucleotide gated cation channel 0.0031 0.0009 0.0009
Schistosoma mansoni ferritin 0.0106 0.0087 0.0087
Trypanosoma cruzi PAB1-binding protein , putative 0.0128 0.0111 0.013
Loa Loa (eye worm) cyclic-nucleotide gated cation channel 0.0031 0.0009 0.0009
Mycobacterium ulcerans extragenic suppressor protein SuhB 0.0228 0.0216 0.0422
Leishmania major DNA polymerase kappa, putative,DNA polymerase IV, putative 0.0121 0.0104 0.0122
Loa Loa (eye worm) hypothetical protein 0.0053 0.0032 0.0036
Leishmania major myo-inositol-1(or 4)-monophosphatase 1, putative 0.0228 0.0216 0.0256
Echinococcus multilocularis ubiquitin specific protease 41 0.0127 0.011 0.011
Echinococcus granulosus nuclear receptor 2DBD gamma 0.0025 0.0002 0.0002
Echinococcus granulosus terminal deoxycytidyl transferase rev1 0.0121 0.0104 0.0104
Loa Loa (eye worm) thioredoxin reductase 0.0256 0.0246 0.0291
Trypanosoma cruzi dihydrolipoyl dehydrogenase, putative 0.0089 0.007 0.0081
Mycobacterium leprae PROBABLE NADH DEHYDROGENASE NDH 0.0584 0.0591 0.8958
Echinococcus multilocularis dna polymerase eta 0.0147 0.0131 0.0131
Entamoeba histolytica phosphatidylinositol-4,5-bisphosphate 3-kinase, putative 0.0551 0.0556 0.066
Echinococcus multilocularis FTZ F1 alpha 0.0053 0.0032 0.0032
Echinococcus multilocularis hyperpolarization activated cyclic 0.0031 0.0009 0.0009
Trypanosoma brucei unspecified product 0.0084 0.0064 0.0075
Schistosoma mansoni voltage-gated potassium channel 0.0031 0.0009 0.0009
Onchocerca volvulus 0.0089 0.007 0.0374
Toxoplasma gondii ImpB/MucB/SamB family protein 0.0063 0.0043 0.0067
Echinococcus multilocularis nervana 2 0.004 0.0019 0.0019
Schistosoma mansoni myo inositol monophosphatase 0.0024 0.0001 0.0001
Brugia malayi Glycosyl hydrolases family 31 protein 0.0038 0.0016 0.0018
Trypanosoma cruzi DNA polymerase kappa, putative 0.0121 0.0104 0.0122
Echinococcus granulosus phosphatidylinositol 3 kinase catalytic subunit 0.0551 0.0556 0.0556
Echinococcus multilocularis thyroid hormone receptor alpha 0.0324 0.0317 0.0317
Echinococcus multilocularis TGF beta signal transducer SmadC 0.0135 0.0119 0.0119
Loa Loa (eye worm) Pin1-type peptidyl-prolyl cis-trans isomerase 0.0033 0.0011 0.0012
Brugia malayi nuclear hormone receptor family member odr-7 0.0025 0.0002 0.0002
Mycobacterium ulcerans lipase LipD 0.0072 0.0052 0.01
Schistosoma mansoni hypothetical protein 0.0257 0.0246 0.0246
Loa Loa (eye worm) hypothetical protein 0.0147 0.0131 0.0154
Wolbachia endosymbiont of Brugia malayi bacterioferritin/cytochrome b1 0.0106 0.0087 0.2875
Echinococcus multilocularis tar DNA binding protein 0.0386 0.0382 0.0382
Echinococcus granulosus phosphatidylinositol 4 kinase beta 0.0529 0.0533 0.0533
Echinococcus multilocularis nuclear receptor subfamily 4 group A 0.0025 0.0002 0.0002
Echinococcus multilocularis guanine nucleotide binding protein G(s) subunit 0.0328 0.0321 0.0321
Echinococcus multilocularis 0.0529 0.0533 0.0533
Trypanosoma cruzi DNA damage repair protein, putative 0.0038 0.0016 0.0018
Brugia malayi Nuclear hormone receptor-like 1 0.0028 0.0006 0.0005
Echinococcus multilocularis inositol monophosphatase 0.0024 0.0001 0.0001
Trichomonas vaginalis chromodomain helicase DNA binding protein, putative 0.0025 0.0002 0.0002
Loa Loa (eye worm) nuclear factor I 0.0075 0.0055 0.0064
Brugia malayi beta-lactamase 0.0072 0.0052 0.0061
Brugia malayi AMP-binding enzyme family protein 0.0048 0.0027 0.003
Trypanosoma brucei phosphatidylinositol 3-kinase, putative 0.2721 0.2839 0.3374
Echinococcus granulosus peptidase Clp S14 family 0.0203 0.019 0.019
Trypanosoma cruzi myo-inositol-1(or 4)-monophosphatase 1, putative 0.0228 0.0216 0.0256
Echinococcus multilocularis Nuclear hormone receptor family member nhr 41 0.0053 0.0032 0.0032
Entamoeba histolytica hypothetical protein 0.0529 0.0533 0.0632
Brugia malayi 3-hydroxyacyl-CoA dehydrogenase type II 0.0058 0.0037 0.0043
Plasmodium vivax phosphatidylinositol 4-kinase, putative 0.0529 0.0533 0.9575
Schistosoma mansoni phosphatidylinositol-45-bisphosphate 3-kinase catalytic subunit alpha PI3K 0.0551 0.0556 0.0556
Trypanosoma brucei DNA damage repair protein, putative 0.0038 0.0016 0.0018
Echinococcus granulosus inositol monophosphatase 0.0024 0.0001 0.0001
Echinococcus multilocularis importin subunit beta 1 0.003 0.0008 0.0008
Echinococcus multilocularis Niemann Pick C1 protein 0.0305 0.0297 0.0297
Echinococcus multilocularis pyridine nucleotide disulfide oxidoreductase 0.0024 0.0001 0.0001
Brugia malayi FKBP-type peptidyl-prolyl cis-trans isomerase-59, BmFKBP59 0.0114 0.0097 0.0114
Trichomonas vaginalis D-aminoacylase, putative 0.0072 0.0052 0.0061
Schistosoma mansoni glutamate synthase 0.0024 0.0001 0.0001
Brugia malayi Nuclear hormone receptor family member nhr-25 0.0053 0.0032 0.0036
Leishmania major peptidyl-prolyl cis-trans isomerase/rotamase, putative,PPIase, putative 0.0032 0.001 0.0011
Echinococcus multilocularis potassium:sodium hyperpolarization activated 0.0031 0.0009 0.0009
Schistosoma mansoni Smad4 0.0061 0.004 0.004
Plasmodium falciparum RAC-beta serine/threonine protein kinase 0.0041 0.0019 0.0327
Loa Loa (eye worm) pigment dispersing factor receptor c 0.0812 0.083 0.0985
Trypanosoma brucei phosphatidylinositol 3-kinase tor, putative 0.3785 0.3958 0.4704
Mycobacterium tuberculosis Probable fatty-acid-CoA ligase FadD2 (fatty-acid-CoA synthetase) (fatty-acid-CoA synthase) 0.0048 0.0027 0.0388
Schistosoma mansoni Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) 0.0328 0.0321 0.0321
Echinococcus granulosus sodium:potassium dependent atpase beta subunit 0.004 0.0019 0.0019
Toxoplasma gondii glycosyl hydrolase, family 31 protein 0.0038 0.0016 0.0024
Loa Loa (eye worm) nuclear hormone receptor family member nhr-40 0.0053 0.0032 0.0036
Leishmania major target of rapamycin (TOR) kinase 1, putative 0.802 0.8414 1
Trypanosoma brucei DNA polymerase kappa, putative 0.0121 0.0104 0.0122
Toxoplasma gondii hypothetical protein 0.0024 0.0001 0.0001
Loa Loa (eye worm) hypothetical protein 0.1009 0.1037 0.1232
Trypanosoma cruzi target of rapamycin kinase 3 0.6396 0.6704 0.7968
Echinococcus granulosus 5'partial|histone lysine N methyltransferase SETDB2 0.0215 0.0202 0.0202
Echinococcus multilocularis COUP TF:Svp nuclear hormone receptor 0.0053 0.0032 0.0032
Loa Loa (eye worm) hypothetical protein 0.0053 0.0032 0.0036
Brugia malayi hypothetical protein 0.0028 0.0006 0.0005
Echinococcus multilocularis smad 0.0135 0.0119 0.0119
Trichomonas vaginalis voltage and ligand gated potassium channel, putative 0.0146 0.013 0.0153
Schistosoma mansoni hepatocyte nuclear factor 4-alpha (hnf-4-alpha) 0.0025 0.0002 0.0002
Loa Loa (eye worm) MH2 domain-containing protein 0.0135 0.0119 0.014
Schistosoma mansoni RAR-like nuclear receptor 0.0053 0.0032 0.0032
Schistosoma mansoni transcription factor LCR-F1 0.0438 0.0437 0.0437
Brugia malayi Importin beta-1 subunit 0.003 0.0008 0.0008
Trichomonas vaginalis alpha-glucosidase, putative 0.0038 0.0016 0.0018
Mycobacterium tuberculosis Dihydrolipoamide dehydrogenase LpdC (lipoamide reductase (NADH)) (lipoyl dehydrogenase) (dihydrolipoyl dehydrogenase) (diaphoras 0.0649 0.0659 1
Loa Loa (eye worm) phosphatidylinositol 3 0.0529 0.0533 0.0632
Brugia malayi intermediate filament protein 0.022 0.0208 0.0246
Loa Loa (eye worm) hypothetical protein 0.0667 0.0678 0.0804
Echinococcus multilocularis nuclear receptor 2DBD gamma 0.0025 0.0002 0.0002
Plasmodium falciparum phosphatidylinositol 4-kinase 0.0529 0.0533 0.9575
Entamoeba histolytica phosphatidylinositol 3-kinase 1, putative 0.0216 0.0204 0.0241
Loa Loa (eye worm) RNA recognition domain-containing protein domain-containing protein 0.0386 0.0382 0.0453
Echinococcus multilocularis potassium voltage gated channel subfamily H 0.0045 0.0024 0.0024
Trichomonas vaginalis phopsphatidylinositol 3-kinase, drosophila, putative 0.0529 0.0533 0.0632
Echinococcus granulosus nuclear receptor subfamily 1 group D 0.0028 0.0006 0.0006
Loa Loa (eye worm) hypothetical protein 0.0072 0.0052 0.0061
Trypanosoma cruzi CAAX prenyl protease 2, putative 0.0092 0.0073 0.0086
Onchocerca volvulus Huntingtin homolog 0.0132 0.0115 0.0622
Trichomonas vaginalis PIKK family atypical protein kinase 0.802 0.8414 1
Echinococcus granulosus CAAX prenyl protease 2 0.0092 0.0073 0.0073
Onchocerca volvulus Inositol monophosphatase 3 homolog 0.0024 0.0001 0.0002
Echinococcus granulosus potassium voltage gated channel subfamily H 0.0045 0.0024 0.0024
Loa Loa (eye worm) glycosyl hydrolase family 31 protein 0.0169 0.0154 0.0182
Trypanosoma cruzi dihydrolipoyl dehydrogenase, putative 0.0089 0.007 0.0081
Trichomonas vaginalis Clan CA, family C19, ubiquitin hydrolase-like cysteine peptidase 0.0127 0.011 0.013
Mycobacterium leprae PROBABLE ATP-DEPENDENT CLP PROTEASE PROTEOLYTIC SUBUNIT 2 CLPP2 (ENDOPEPTIDASE CLP 2) 0.0309 0.0302 0.4571
Trypanosoma cruzi phosphatidylinositol kinase related protein, putative 0.0529 0.0533 0.0632
Schistosoma mansoni microtubule-associated protein tau 0.9528 1 1
Leishmania major DNA polymerase kappa, putative 0.0038 0.0016 0.0018
Trichomonas vaginalis D-aminoacylase, putative 0.0072 0.0052 0.0061
Brugia malayi Probable ClpP-like protease 0.0309 0.0302 0.0358
Mycobacterium ulcerans long-chain fatty-acid CoA ligase 0.0048 0.0027 0.005
Echinococcus granulosus thyroid hormone receptor alpha 0.0025 0.0002 0.0002
Loa Loa (eye worm) nuclear Hormone Receptor family member 0.0053 0.0032 0.0036
Echinococcus multilocularis Basic leucine zipper (bZIP) transcription 0.0438 0.0437 0.0437
Schistosoma mansoni ubiquitin-specific peptidase 8 (C19 family) 0.0127 0.011 0.011
Echinococcus multilocularis lysosomal alpha glucosidase 0.0169 0.0154 0.0154
Brugia malayi nuclear hormone receptor 0.0053 0.0032 0.0036
Toxoplasma gondii ATP-dependent Clp endopeptidase, proteolytic subunit ClpP domain-containing protein 0.0309 0.0302 0.048
Onchocerca volvulus 0.0058 0.0037 0.0197
Echinococcus multilocularis nuclear receptor nhr 48 0.0025 0.0002 0.0002
Loa Loa (eye worm) hypothetical protein 0.1184 0.1221 0.1451
Schistosoma mansoni voltage-gated potassium channel 0.0045 0.0024 0.0024
Trypanosoma cruzi FK506-binding protein (FKBP)-type peptidyl-prolyl isomerase, putative 0.0114 0.0097 0.0114
Trypanosoma brucei DNA polymerase IV, putative 0.0121 0.0104 0.0122
Leishmania major target of rapamycin kinase (TOR) kinase 3 0.6396 0.6704 0.7968
Trypanosoma cruzi phosphatidylinositol 4-kinase alpha, putative 0.0551 0.0556 0.066
Schistosoma mansoni hypothetical protein 0.0057 0.0036 0.0036
Echinococcus multilocularis cyclic nucleotide gated cation channel alpha 3 0.0031 0.0009 0.0009
Schistosoma mansoni zinc finger protein 0.0025 0.0002 0.0002
Echinococcus granulosus Niemann Pick C1 protein 0.0436 0.0434 0.0434
Entamoeba histolytica hypothetical protein 0.0438 0.0437 0.0518
Loa Loa (eye worm) hypothetical protein 0.0036 0.0014 0.0015
Echinococcus granulosus phosphatidylinositol 4 kinase alpha 0.0551 0.0556 0.0556
Schistosoma mansoni nuclear receptor 2DBD-gamma 0.0053 0.0032 0.0032
Schistosoma mansoni coup transcription factor 0.0053 0.0032 0.0032
Schistosoma mansoni nuclear receptor 0.0025 0.0002 0.0002
Trypanosoma brucei ubiquitin carboxyl-terminal hydrolase, putative 0.0127 0.011 0.013
Trypanosoma brucei CAAX amino terminal protease, putative 0.0092 0.0073 0.0086
Leishmania major aldehyde dehydrogenase, mitochondrial precursor 0.0184 0.017 0.02
Trichomonas vaginalis PIKK family atypical protein kinase 0.6389 0.6698 0.796
Loa Loa (eye worm) hypothetical protein 0.0025 0.0002 0.0002
Trypanosoma brucei mitochondrial DNA polymerase beta-PAK 0.0141 0.0125 0.0147
Schistosoma mansoni DNA polymerase eta 0.0147 0.0131 0.0131
Brugia malayi ImpB/MucB/SamB family protein 0.0147 0.0131 0.0154
Echinococcus granulosus dihydropyrimidine dehydrogenase NADP 0.0024 0.0001 0.0001
Loa Loa (eye worm) heterochromatin protein 1 0.0072 0.0052 0.0061
Echinococcus granulosus apoptosis inducing factor 1 mitochondrial 0.0024 0.0001 0.0001
Loa Loa (eye worm) nuclear hormone receptor family member nhr-14 0.0053 0.0032 0.0036
Trypanosoma cruzi DNA polymerase beta thumb, putative 0.0042 0.002 0.0023
Loa Loa (eye worm) phosphatidylinositol 3 0.0529 0.0533 0.0632
Echinococcus granulosus nuclear receptor 2DBD gamma 0.0053 0.0032 0.0032
Brugia malayi alpha keto acid dehydrogenase complex, E3 component, lipoamide dehydrogenase 0.0065 0.0045 0.0052
Echinococcus multilocularis chromobox protein 1 0.0072 0.0052 0.0052
Trichomonas vaginalis PIKK family atypical protein kinase 0.2721 0.2839 0.3374
Entamoeba histolytica hypothetical protein 0.0024 0.0002 0.0001
Onchocerca volvulus 0.0072 0.0052 0.0277
Brugia malayi MH2 domain containing protein 0.0135 0.0119 0.014
Echinococcus granulosus dihydrolipoamide dehydrogenase 0.0089 0.007 0.007
Leishmania major dihydrolipoamide dehydrogenase, putative 0.0089 0.007 0.0081
Trichomonas vaginalis PIKK family atypical protein kinase 0.5977 0.6264 0.7445
Loa Loa (eye worm) hypothetical protein 0.0025 0.0002 0.0002
Trypanosoma brucei DNA polymerase kappa, putative 0.0121 0.0104 0.0122
Loa Loa (eye worm) FKBP-type peptidyl-prolyl cis-trans isomerase-12 0.0114 0.0097 0.0114
Trichomonas vaginalis myo inositol monophosphatase, putative 0.0228 0.0216 0.0256
Echinococcus granulosus nuclear receptor nhr 48 0.0025 0.0002 0.0002
Brugia malayi chromobox protein homolog 3 0.004 0.0019 0.0021
Leishmania major importin beta-1 subunit, putative 0.0024 0.0002 0.0001
Schistosoma mansoni immunophilin FK506 binding protein FKBP12 0.0114 0.0097 0.0097
Echinococcus multilocularis nuclear receptor 2DBD gamma 0.0053 0.0032 0.0032
Entamoeba histolytica phosphatidylinositol3-kinaseTor2, putative 0.802 0.8414 1
Schistosoma mansoni pap-inositol-14-phosphatase 0.0024 0.0001 0.0001
Trypanosoma cruzi phosphatidylinositol 3-kinase 2, putative 0.0745 0.076 0.0903
Mycobacterium ulcerans monophosphatase CysQ 0.0024 0.0001 0.0001
Schistosoma mansoni ataxia telangiectasia mutated (atm) 0.1538 0.1594 0.1594
Schistosoma mansoni Smad4 0.0135 0.0119 0.0119
Mycobacterium ulcerans hypothetical protein 0.0072 0.0052 0.01
Schistosoma mansoni cellular tumor antigen P53 0.076 0.0775 0.0775
Echinococcus granulosus ecdysone induced protein 78C 0.0053 0.0032 0.0032
Mycobacterium ulcerans dihydrolipoamide dehydrogenase, LpdB 0.0089 0.007 0.0134
Schistosoma mansoni sulfide quinone reductase 0.0024 0.0001 0.0001
Mycobacterium ulcerans hypothetical protein 0.0157 0.0142 0.0276
Plasmodium falciparum DNA repair protein REV1, putative 0.0038 0.0016 0.0267
Entamoeba histolytica protein kinase, putative 0.0065 0.0045 0.0052
Onchocerca volvulus 0.0025 0.0002 0.0008
Trichomonas vaginalis chromodomain-helicase-DNA-binding protein, putative 0.0025 0.0002 0.0002
Echinococcus multilocularis lamin dm0 0.022 0.0208 0.0208
Echinococcus granulosus cadherin EGF LAG seven pass G type receptor 0.0257 0.0246 0.0246
Schistosoma mansoni histone-lysine n-methyltransferase suv9 0.0236 0.0224 0.0224
Trypanosoma cruzi Phosphatidylinositol 3-kinase tor1 0.802 0.8414 1
Trichomonas vaginalis AGC family protein kinase 0.0065 0.0045 0.0052
Schistosoma mansoni Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) 0.0328 0.0321 0.0321
Schistosoma mansoni family U48 unassigned peptidase (U48 family) 0.0092 0.0073 0.0073
Trypanosoma cruzi hypothetical protein, conserved 0.0072 0.0052 0.0061
Echinococcus multilocularis protein patched 0.0131 0.0114 0.0114
Trichomonas vaginalis penicillin-binding protein, putative 0.0072 0.0052 0.0061
Trypanosoma cruzi hypothetical protein, conserved 0.0072 0.0052 0.0061
Schistosoma mansoni terminal deoxycytidyl transferase 0.0121 0.0104 0.0104
Schistosoma mansoni apoferritin-2 0.0106 0.0087 0.0087
Echinococcus multilocularis Zinc finger, PHD finger 0.0551 0.0556 0.0556
Echinococcus granulosus expressed protein 0.0106 0.0087 0.0087
Plasmodium vivax glutathione reductase, putative 0.0256 0.0246 0.4404
Brugia malayi conserved hypotetical protein 0.0025 0.0002 0.0002
Mycobacterium ulcerans acyl-CoA synthetase 0.0048 0.0027 0.005
Brugia malayi nuclear receptor RXR 0.0028 0.0006 0.0005
Brugia malayi nuclear receptor RXR 0.0025 0.0002 0.0002
Onchocerca volvulus Steroid hormone receptor family member cnr14 homolog 0.0053 0.0032 0.0167
Onchocerca volvulus Heterochromatin protein 1 homolog 0.0043 0.0022 0.0114
Entamoeba histolytica myo-inositol monophosphatase, putative 0.0228 0.0216 0.0256
Mycobacterium tuberculosis Probable oxidoreductase 0.0649 0.0659 1
Brugia malayi Protein kinase domain containing protein 0.0065 0.0045 0.0052
Echinococcus granulosus serine protein kinase ATM 0.1538 0.1594 0.1594
Trichomonas vaginalis PIKK family atypical protein kinase 0.6389 0.6698 0.796
Echinococcus granulosus calcium:calmodulin dependent protein kinase 0.0041 0.0019 0.0019
Entamoeba histolytica PH domain containing protein kinase, putative 0.0045 0.0023 0.0027
Echinococcus granulosus histone lysine N methyltransferase MLL3 0.0026 0.0004 0.0004
Loa Loa (eye worm) hypothetical protein 0.0053 0.0032 0.0036
Trypanosoma brucei dihydrolipoamide dehydrogenase 0.0089 0.007 0.0081
Mycobacterium tuberculosis Probable lipase LipE 0.0072 0.0052 0.0774
Loa Loa (eye worm) hypothetical protein 0.0079 0.0059 0.0069
Mycobacterium tuberculosis Probable nitrite reductase [NAD(P)H] large subunit [FAD flavoprotein] NirB 0.0584 0.0591 0.8958
Trypanosoma brucei phosphatidylinositol 3-kinase, putative 0.0597 0.0604 0.0717
Brugia malayi photoreceptor-specific nuclear receptor 0.0053 0.0032 0.0036
Mycobacterium tuberculosis Fatty-acid-AMP ligase FadD30 (fatty-acid-AMP synthetase) (fatty-acid-AMP synthase) 0.0036 0.0014 0.0195
Plasmodium falciparum ataxin-2 like protein, putative 0.0128 0.0111 0.1973
Trypanosoma brucei DNA polymerase kappa, putative 0.0084 0.0064 0.0075
Loa Loa (eye worm) glutathione reductase 0.0256 0.0246 0.0291
Echinococcus granulosus Phosphatidylinositol 4 kinase type 2 beta 0.0529 0.0533 0.0533
Mycobacterium leprae PROBABLE BACTERIOFERRITIN BFRA 0.0106 0.0087 0.1314
Giardia lamblia Ubiquitin carboxyl-terminal hydrolase 4 0.0127 0.011 0.013
Wolbachia endosymbiont of Brugia malayi fructose-1,6-bisphosphatase 0.0228 0.0216 0.715
Brugia malayi Nuclear hormone receptor E75 0.0025 0.0002 0.0002
Loa Loa (eye worm) nucleolar RNA-associated protein alpha 0.032 0.0313 0.037
Schistosoma mansoni serine/threonine-protein kinase 0.0045 0.0023 0.0023
Trichomonas vaginalis PIKK family atypical protein kinase 0.2721 0.2839 0.3374
Loa Loa (eye worm) hypothetical protein 0.0075 0.0055 0.0064
Leishmania major acetoin dehydrogenase e3 component-like protein 0.0089 0.007 0.0081
Echinococcus multilocularis expressed conserved protein 0.0286 0.0277 0.0277
Schistosoma mansoni histone-lysine n-methyltransferase setb1 0.0224 0.0212 0.0212
Mycobacterium tuberculosis Monophosphatase CysQ 0.0024 0.0001 0.0006
Mycobacterium tuberculosis Conserved hypothetical protein 0.0529 0.0533 0.8079
Schistosoma mansoni phosphatidylinositol 4-kinase type-II 0.0529 0.0533 0.0533
Echinococcus multilocularis snurportin 1 0.032 0.0313 0.0313
Loa Loa (eye worm) hypothetical protein 0.0025 0.0002 0.0002
Trypanosoma cruzi rac serine-threonine kinase, putative 0.0045 0.0023 0.0027
Plasmodium falciparum phosphatidylinositol 3-kinase 0.0551 0.0556 1
Trichomonas vaginalis PIKK family atypical protein kinase 0.4353 0.4555 0.5414
Echinococcus multilocularis mothers against decapentaplegic 6 0.0061 0.004 0.004
Loa Loa (eye worm) MH1 domain-containing protein 0.0061 0.004 0.0046
Trichomonas vaginalis set domain proteins, putative 0.1769 0.1837 0.2182
Trypanosoma brucei Phosphatidylinositol 3-kinase tor1 0.802 0.8414 1
Leishmania major fk506-binding protein 1-like protein 0.0114 0.0097 0.0114
Toxoplasma gondii inositol(myo)-1(or 4)-monophosphatase 2, putative 0.0228 0.0216 0.0343
Trypanosoma brucei DNA polymerase beta thumb, putative 0.0042 0.002 0.0023
Trypanosoma brucei FK506-binding protein (FKBP)-type peptidyl-prolyl isomerase, putative 0.0114 0.0097 0.0114
Echinococcus multilocularis atpase aaa+ type core atpase aaa type core 0.2458 0.2562 0.2562
Loa Loa (eye worm) hypothetical protein 0.0216 0.0203 0.0241
Trypanosoma brucei DNA polymerase IV, putative 0.0121 0.0104 0.0122
Trypanosoma cruzi phosphatidylinositol 3-related kinase, putative 0.2779 0.2899 0.3445
Echinococcus granulosus Peptidase C19 ubiquitin carboxyl terminal hydrolase 2 0.0127 0.011 0.011
Entamoeba histolytica Niemann-Pick C1 protein, putative 0.0305 0.0297 0.0352
Schistosoma mansoni histone-lysine n-methyltransferase setb1 0.0224 0.0212 0.0212
Mycobacterium tuberculosis Probable fatty-acid-CoA ligase FadD5 (fatty-acid-CoA synthetase) (fatty-acid-CoA synthase) 0.0034 0.0012 0.0164
Loa Loa (eye worm) hypothetical protein 0.0529 0.0533 0.0632
Trypanosoma cruzi dihydrolipoamide dehydrogenase, putative 0.0089 0.007 0.0081
Schistosoma mansoni tar DNA-binding protein 0.0386 0.0382 0.0382
Brugia malayi Phosphatidylinositol 3- and 4-kinase family protein 0.0529 0.0533 0.0632
Schistosoma mansoni hypothetical protein 0.0826 0.0845 0.0845
Brugia malayi dihydrolipoyl dehydrogenase, mitochondrial precursor, putative 0.0089 0.007 0.0081
Echinococcus multilocularis diuretic hormone 44 receptor GPRdih2 0.0257 0.0246 0.0246
Echinococcus granulosus inositol monophosphatase 1 0.0228 0.0216 0.0216
Loa Loa (eye worm) hypothetical protein 0.0025 0.0002 0.0002
Trichomonas vaginalis AGC family protein kinase 0.0065 0.0045 0.0052
Echinococcus multilocularis PIK kinase, FAT and Armadillo domain containing protein 0.1184 0.1221 0.1221
Echinococcus multilocularis neutral alpha glucosidase AB 0.0038 0.0016 0.0016
Schistosoma mansoni chromobox protein 0.0072 0.0052 0.0052
Schistosoma mansoni ubiquitin-specific peptidase 2 (C19 family) 0.0127 0.011 0.011
Echinococcus granulosus serine/threonine protein kinase 0.0045 0.0023 0.0023
Trypanosoma brucei DNA polymerase kappa, putative 0.0121 0.0104 0.0122
Echinococcus multilocularis tumor protein p63 0.519 0.5436 0.5436
Brugia malayi latrophilin 2 splice variant baaae 0.0555 0.056 0.0664
Trypanosoma cruzi mitochondrial DNA polymerase beta-PAK, putative 0.0042 0.002 0.0023
Echinococcus granulosus diuretic hormone 44 receptor GPRdih2 0.0257 0.0246 0.0246
Schistosoma mansoni Smad4 0.0061 0.004 0.004
Leishmania major phosphatidylinositol kinase related protein, putative 0.0529 0.0533 0.0632
Schistosoma mansoni peptidase Clp (S14 family) 0.0309 0.0302 0.0302
Trichomonas vaginalis conserved hypothetical protein 0.1713 0.1778 0.2112
Trichomonas vaginalis PIKK family atypical protein kinase 0.1538 0.1594 0.1893
Schistosoma mansoni aldehyde dehydrogenase 0.0184 0.017 0.017
Plasmodium falciparum thioredoxin reductase 0.0089 0.007 0.1234
Onchocerca volvulus 0.0529 0.0533 0.2896
Trichomonas vaginalis PIKK family atypical protein kinase 0.5977 0.6264 0.7445
Plasmodium vivax acyl-CoA synthetase, putative 0.0036 0.0014 0.0231
Toxoplasma gondii phosphatidylinositol 3- and 4-kinase 0.0529 0.0533 0.0849
Brugia malayi Nuclear hormone receptor family member nhr-49 0.0053 0.0032 0.0036
Brugia malayi nuclear hormone receptor 0.0025 0.0002 0.0002
Onchocerca volvulus 0.0025 0.0002 0.0008
Brugia malayi polk-prov protein 0.0038 0.0016 0.0018
Plasmodium vivax rac-beta serine/threonine protein kinase, putative 0.0041 0.0019 0.0327
Onchocerca volvulus 0.0149 0.0133 0.072
Trypanosoma brucei peptidyl-prolyl cis-trans isomerase, putative 0.0114 0.0097 0.0114
Mycobacterium leprae Probable monophosphatase 0.0024 0.0001 0.0006
Echinococcus multilocularis cytoplasmic intermediate filament protein 0.0106 0.0088 0.0088
Giardia lamblia DNA damage repair protein 0.0038 0.0016 0.0018
Plasmodium falciparum glutathione reductase 0.0089 0.007 0.1234
Brugia malayi ecdysone receptor 0.0025 0.0002 0.0002
Echinococcus granulosus geminin 0.0353 0.0347 0.0347
Trypanosoma brucei DNA polymerase kappa, putative 0.0121 0.0104 0.0122
Mycobacterium tuberculosis Conserved protein 0.0072 0.0052 0.0774
Echinococcus multilocularis Peptidase C19, ubiquitin carboxyl terminal hydrolase 2 0.0127 0.011 0.011
Trypanosoma brucei hypothetical protein, conserved 0.0038 0.0016 0.0018
Trichomonas vaginalis PIKK family atypical protein kinase 0.155 0.1607 0.1909
Chlamydia trachomatis dihydrolipoyl dehydrogenase 0.0089 0.007 0.2279
Trichomonas vaginalis conserved hypothetical protein 0.0029 0.0006 0.0006
Schistosoma mansoni intermediate filament proteins 0.022 0.0208 0.0208
Loa Loa (eye worm) intermediate filament protein 0.022 0.0208 0.0246
Loa Loa (eye worm) AGC/RSK/P70 protein kinase 0.0061 0.0041 0.0047
Entamoeba histolytica hypothetical protein 0.0529 0.0533 0.0632
Schistosoma mansoni cyclic-nucleotide-gated cation channel 0.0031 0.0009 0.0009
Trypanosoma cruzi phosphatidylinositol kinase, putative 0.0529 0.0533 0.0632
Echinococcus multilocularis hyperpolarization activated cyclic 0.0031 0.0009 0.0009
Entamoeba histolytica hypothetical protein 0.0438 0.0437 0.0518
Echinococcus multilocularis phosphatidylinositol 4 kinase alpha 0.0551 0.0556 0.0556
Mycobacterium tuberculosis Possible penicillin-binding protein 0.046 0.046 0.6974
Trichomonas vaginalis immunophilin, putative 0.0114 0.0097 0.0114
Leishmania major mitochondrial DNA polymerase beta-PAK, putative 0.0141 0.0125 0.0147
Entamoeba histolytica phosphatidylinositol 3-kinase, putative 0.0597 0.0604 0.0717
Echinococcus granulosus Protein patched homolog 1 0.0131 0.0114 0.0114
Entamoeba histolytica hypothetical protein 0.07 0.0712 0.0846
Schistosoma mansoni smad 0.0135 0.0119 0.0119
Echinococcus multilocularis inositol monophosphatase 1 0.0228 0.0216 0.0216
Trichomonas vaginalis chromodomain helicase DNA binding protein, putative 0.0025 0.0002 0.0002
Echinococcus multilocularis ecdysone induced protein 78C 0.0053 0.0032 0.0032
Trypanosoma brucei DNA polymerase kappa, putative 0.0121 0.0104 0.0122
Plasmodium vivax hypothetical protein, conserved 0.0072 0.0052 0.0917
Trichomonas vaginalis PIKK family atypical protein kinase 0.5977 0.6264 0.7445
Echinococcus multilocularis Niemann Pick C1 protein 0.0436 0.0434 0.0434
Trypanosoma brucei phosphatidylinositol 3-kinase catalytic subunit, putative 0.0529 0.0533 0.0632
Echinococcus granulosus dna polymerase kappa 0.0121 0.0104 0.0104
Mycobacterium tuberculosis Conserved hypothetical protein 0.0157 0.0142 0.2137
Loa Loa (eye worm) hypothetical protein 0.0025 0.0002 0.0002
Schistosoma mansoni hyperpolarization activated cyclic nucleotide-gated potassium channel 0.0031 0.0009 0.0009
Plasmodium falciparum importin beta, putative 0.003 0.0008 0.0121
Mycobacterium tuberculosis Possible DNA-damage-inducible protein P DinP (DNA polymerase V) (pol IV 2) (DNA nucleotidyltransferase (DNA-directed)) 0.0121 0.0104 0.1563
Echinococcus multilocularis rac serine:threonine kinase 0.0045 0.0023 0.0023
Loa Loa (eye worm) cyclic-nucleotide gated cation channel 0.0031 0.0009 0.0009
Trypanosoma brucei DNA polymerase IV, putative 0.0121 0.0104 0.0122
Schistosoma mansoni nuclear hormone receptor nor-1/nor-2 0.0053 0.0032 0.0032
Schistosoma mansoni 3-hydroxyacyl-CoA dehydrogenase 0.0058 0.0037 0.0037
Trichomonas vaginalis peptidylprolyl isomerase, putative 0.0114 0.0097 0.0114
Schistosoma mansoni hypothetical protein 0.0257 0.0246 0.0246
Brugia malayi FKBP-type peptidyl-prolyl cis-trans isomerase-12, BmFKBP-12 0.0114 0.0097 0.0114
Trichomonas vaginalis voltage and ligand gated potassium channel, putative 0.0031 0.0009 0.0009
Toxoplasma gondii BRCA1 C Terminus (BRCT) domain-containing protein 0.0038 0.0016 0.0024
Trichomonas vaginalis PIKK family atypical protein kinase 0.1009 0.1037 0.1232
Trypanosoma cruzi dihydrolipoamide dehydrogenase, putative 0.0089 0.007 0.0081
Trichomonas vaginalis PIKK family atypical protein kinase 0.6389 0.6698 0.796
Echinococcus granulosus cyclic nucleotide gated cation channel 0.0031 0.0009 0.0009
Echinococcus granulosus lysosomal alpha glucosidase 0.0169 0.0154 0.0154
Brugia malayi Heterochromatin protein 1 0.0072 0.0052 0.0061
Loa Loa (eye worm) latrophilin receptor protein 2 0.0257 0.0246 0.0292
Mycobacterium tuberculosis Probable conserved lipoprotein 0.0072 0.0052 0.0774
Brugia malayi F/Y-rich N-terminus family protein 0.0026 0.0003 0.0003
Mycobacterium tuberculosis Probable fatty-acid-CoA ligase FadD35 (fatty-acid-CoA synthetase) (fatty-acid-CoA synthase) 0.0034 0.0012 0.0164
Plasmodium vivax hypothetical protein 0.0529 0.0533 0.9575
Trichomonas vaginalis PIKK family atypical protein kinase 0.2154 0.2242 0.2664
Schistosoma mansoni nuclear hormone receptor 0.0025 0.0002 0.0002
Loa Loa (eye worm) transcription factor SMAD2 0.1988 0.2067 0.2456
Loa Loa (eye worm) beta-LACTamase domain containing family member 0.0072 0.0052 0.0061
Trichomonas vaginalis phosphatidylinositol kinase, putative 0.0551 0.0556 0.066
Trichomonas vaginalis phopsphatidylinositol 3-kinase, drosophila, putative 0.0745 0.076 0.0903
Mycobacterium ulcerans beta-lactamase 0.0072 0.0052 0.01
Brugia malayi Phosphatidylinositol 3- and 4-kinase family protein 0.0597 0.0604 0.0717
Brugia malayi ImpB/MucB/SamB family protein 0.0121 0.0104 0.0122
Loa Loa (eye worm) steroid hormone receptor 0.0053 0.0032 0.0036
Echinococcus multilocularis Phosphatidylinositol 4 kinase type 2 beta 0.0529 0.0533 0.0533
Chlamydia trachomatis acylglycerophosphoethanolamine acyltransferase 0.0036 0.0014 0.0426
Echinococcus granulosus expressed protein 0.0033 0.0011 0.0011
Brugia malayi p70 ribosomal S6 kinase beta 0.0061 0.0041 0.0047
Trichomonas vaginalis PIKK family atypical protein kinase 0.4794 0.5019 0.5965
Brugia malayi Glycosyl hydrolases family 31 protein 0.0169 0.0154 0.0182
Echinococcus multilocularis nuclear receptor 2DBD gamma 0.0053 0.0032 0.0032
Trichomonas vaginalis myo inositol monophosphatase, putative 0.0228 0.0216 0.0256
Trypanosoma brucei phosphatidylinositol 4-kinase, putative 0.802 0.8414 1
Echinococcus multilocularis cpg binding protein 0.0061 0.0041 0.0041
Brugia malayi glutathione reductase 0.0256 0.0246 0.0291
Echinococcus granulosus peptidyl prolyl cis trans isomerase FKBP4 0.0114 0.0097 0.0097
Mycobacterium ulcerans hypothetical protein 0.0048 0.0027 0.005
Trichomonas vaginalis PIKK family atypical protein kinase 0.4346 0.4548 0.5405
Echinococcus multilocularis Nuclear hormone receptor HR96 0.0025 0.0002 0.0002
Schistosoma mansoni cyclic-nucleotide-gated cation channel 0.0031 0.0009 0.0009
Echinococcus multilocularis Phosphatidylinositol 4 kinase type 2 beta 0.0529 0.0533 0.0533
Trichomonas vaginalis PIKK family atypical protein kinase 0.5977 0.6264 0.7445
Schistosoma mansoni smad1 5 8 and 0.0135 0.0119 0.0119
Trichomonas vaginalis PIKK family atypical protein kinase 0.4353 0.4555 0.5414
Trypanosoma cruzi DNA damage repair protein, putative 0.0038 0.0016 0.0018
Trichomonas vaginalis phosphatidylinositol 3-kinase catalytic subunit alpha, beta, delta, putative 0.0676 0.0687 0.0815
Schistosoma mansoni patched 1 0.0131 0.0114 0.0114
Loa Loa (eye worm) hypothetical protein 0.0102 0.0084 0.0098
Trichomonas vaginalis PIKK family atypical protein kinase 0.6389 0.6698 0.796
Schistosoma mansoni ferritin light chain 0.0106 0.0087 0.0087
Trypanosoma cruzi DNA polymerase eta, putative 0.0147 0.0131 0.0154
Brugia malayi Calcitonin receptor-like protein seb-1 0.0812 0.083 0.0985
Brugia malayi Phosphatidylinositol 3- and 4-kinase family protein 0.0529 0.0533 0.0632
Trichomonas vaginalis chromodomain-helicase-DNA-binding protein, putative 0.0025 0.0002 0.0002
Schistosoma mansoni immunophilin 0.0114 0.0097 0.0097
Trichomonas vaginalis PIKK family atypical protein kinase 0.4353 0.4555 0.5414
Leishmania major hypothetical protein, conserved 0.0072 0.0052 0.0061
Trichomonas vaginalis mercuric reductase, putative 0.0089 0.007 0.0081
Trichomonas vaginalis PIKK family atypical protein kinase 0.6837 0.7168 0.852
Trichomonas vaginalis phosphatidylinositol 3-kinase class, putative 0.0676 0.0687 0.0815
Trichomonas vaginalis neutral alpha-glucosidase ab precursor, putative 0.0038 0.0016 0.0018
Entamoeba histolytica deoxycytidyl transferase, putative 0.0121 0.0104 0.0122
Trichomonas vaginalis phosphatidylinositol 3-kinase class, putative 0.0551 0.0556 0.066
Brugia malayi hypothetical protein 0.0025 0.0002 0.0002
Trichomonas vaginalis phosphatidylinositol 3-kinase catalytic subunit gamma, putative 0.0745 0.076 0.0903
Schistosoma mansoni phosphatidylinositol 3-kinase class 0.0529 0.0533 0.0533
Loa Loa (eye worm) hypothetical protein 0.0028 0.0006 0.0005
Toxoplasma gondii pyruvate dehydrogenase complex subunit PDH-E3II 0.0089 0.007 0.0109
Loa Loa (eye worm) hypothetical protein 0.0048 0.0027 0.003
Plasmodium falciparum phosphatidylinositol 3- and 4-kinase, putative 0.0529 0.0533 0.9575
Trypanosoma cruzi DNA polymerase kappa, putative 0.0121 0.0104 0.0122
Onchocerca volvulus 0.1769 0.1837 1
Mycobacterium ulcerans DNA polymerase IV 0.0121 0.0104 0.0202
Echinococcus granulosus 3 hydroxyacyl coenzyme A dehydrogenase type 2 0.0058 0.0037 0.0037
Schistosoma mansoni voltage-gated potassium channel 0.017 0.0156 0.0156
Loa Loa (eye worm) phosphatidylinositol 3 0.802 0.8414 1
Echinococcus multilocularis expressed protein 0.0106 0.0087 0.0087
Plasmodium vivax thioredoxin reductase, putative 0.0256 0.0246 0.4404
Echinococcus granulosus lamin dm0 0.022 0.0208 0.0208
Echinococcus granulosus guanine nucleotide binding protein Gs subunit 0.0328 0.0321 0.0321
Schistosoma mansoni retinoic acid receptor RXR 0.0053 0.0032 0.0032
Schistosoma mansoni hypothetical protein 0.0555 0.056 0.056
Echinococcus granulosus dnaJ subfamily B 0.0826 0.0845 0.0845
Mycobacterium tuberculosis NADPH-dependent mycothiol reductase Mtr 0.0256 0.0246 0.3716
Loa Loa (eye worm) histone methyltransferase 0.0026 0.0004 0.0003
Brugia malayi Phosphatidylinositol 3- and 4-kinase family protein 0.802 0.8414 1
Loa Loa (eye worm) hypothetical protein 0.0305 0.0297 0.0352
Loa Loa (eye worm) hypothetical protein 0.0028 0.0006 0.0005
Brugia malayi Nuclear hormone receptor family member nhr-3 0.0053 0.0032 0.0036
Echinococcus multilocularis aldehyde dehydrogenase, mitochondrial 0.0184 0.017 0.017
Mycobacterium ulcerans hypothetical protein 0.0038 0.0016 0.0029
Leishmania major 2-oxoglutarate dehydrogenase, e3 component, lipoamidedehydrogenase-like protein 0.0089 0.007 0.0081
Loa Loa (eye worm) hypothetical protein 0.0555 0.056 0.0664
Entamoeba histolytica glycosyl hydrolase, family 31 protein 0.0038 0.0016 0.0018
Brugia malayi MH2 domain containing protein 0.0135 0.0119 0.014
Schistosoma mansoni voltage-gated potassium channel 0.0025 0.0002 0.0002
Brugia malayi Thioredoxin reductase 0.0256 0.0246 0.0291
Brugia malayi AMP-binding enzyme family protein 0.0048 0.0027 0.003
Giardia lamblia GTOR 0.802 0.8414 1
Mycobacterium tuberculosis Probable reductase 0.0584 0.0591 0.8958
Leishmania major ubiquitin hydrolase, putative,cysteine peptidase, Clan CA, family C19, putative 0.0127 0.011 0.013
Mycobacterium ulcerans ATP-dependent Clp protease proteolytic subunit 0.0309 0.0302 0.059
Entamoeba histolytica PH domain containing protein kinase, putative 0.0045 0.0023 0.0027
Trichomonas vaginalis chromodomain helicase DNA binding protein, putative 0.0025 0.0002 0.0002
Brugia malayi MH1 domain containing protein 0.0075 0.0055 0.0064
Echinococcus multilocularis ATP dependent Clp protease proteolytic subunit 0.0309 0.0302 0.0302
Mycobacterium leprae POSSIBLE MONOPHOSPHATASE CYSQ 0.0024 0.0001 0.0006
Echinococcus multilocularis histone lysine N methyltransferase MLL3 0.0026 0.0004 0.0004
Trichomonas vaginalis phosphatidylinositol 3-kinase catalytic subunit alpha, beta, delta, putative 0.0597 0.0604 0.0717
Schistosoma mansoni mixed-lineage leukemia protein mll 0.0131 0.0114 0.0114
Trypanosoma cruzi peptidyl-prolyl cis-trans isomerase 0.0032 0.001 0.0011
Loa Loa (eye worm) hypothetical protein 0.0031 0.0009 0.0009
Mycobacterium tuberculosis Putative ferredoxin reductase 0.0584 0.0591 0.8958
Trypanosoma cruzi mitochondrial DNA polymerase beta, putative 0.0299 0.029 0.0344
Echinococcus granulosus hyperpolarization activated cyclic 0.0031 0.0009 0.0009
Brugia malayi MH1 domain containing protein 0.0135 0.0119 0.014
Mycobacterium ulcerans monophosphatase 0.0024 0.0001 0.0001
Mycobacterium tuberculosis Inositol-1-monophosphatase SuhB 0.0204 0.0191 0.2886
Brugia malayi calcium-independent alpha-latrotoxin receptor 2, putative 0.0257 0.0246 0.0292
Trichomonas vaginalis glutathione reductase, putative 0.0089 0.007 0.0081
Brugia malayi GTP-binding regulatory protein Gs alpha-S chain, putative 0.0328 0.0321 0.0381
Mycobacterium leprae DIHYDROLIPOAMIDE DEHYDROGENASE LPD (LIPOAMIDE REDUCTASE (NADH)) (LIPOYL DEHYDROGENASE) (DIHYDROLIPOYL DEHYDROGENASE) (DIAPHORASE 0.0649 0.0659 1
Schistosoma mansoni apoferritin-2 0.0106 0.0087 0.0087
Schistosoma mansoni tar DNA-binding protein 0.0386 0.0382 0.0382
Brugia malayi Intermediate filament tail domain containing protein 0.022 0.0208 0.0246
Loa Loa (eye worm) hypothetical protein 0.0025 0.0002 0.0002
Schistosoma mansoni cpg binding protein 0.0061 0.0041 0.0041
Trypanosoma cruzi phosphatidylinositol 3-related kinase, putative 0.2779 0.2899 0.3445
Onchocerca volvulus Nuclear receptor subfamily 6 group A member 1 homolog 0.0025 0.0002 0.0008
Loa Loa (eye worm) hypothetical protein 0.0025 0.0002 0.0002
Loa Loa (eye worm) hypothetical protein 0.0036 0.0014 0.0015
Echinococcus granulosus serine:threonine protein kinase SMG1 0.1538 0.1594 0.1594
Schistosoma mansoni hypothetical protein 0.0353 0.0347 0.0347
Echinococcus granulosus FTZ F1 nuclear receptor protein 0.0053 0.0032 0.0032
Trypanosoma brucei importin beta-1 subunit, putative 0.003 0.0008 0.0008
Schistosoma mansoni Tr4/Tr2 (homologue) 0.0053 0.0032 0.0032
Loa Loa (eye worm) MH2 domain-containing protein 0.1988 0.2067 0.2456
Mycobacterium tuberculosis Possible conserved lipoprotein LpqK 0.0072 0.0052 0.0774
Leishmania major 4-coumarate:coa ligase-like protein 0.0048 0.0027 0.003
Mycobacterium tuberculosis Probable fatty-acid-CoA ligase FadD3 (fatty-acid-CoA synthetase) (fatty-acid-CoA synthase) 0.0034 0.0012 0.0164
Echinococcus granulosus pyridine nucleotide disulfide oxidoreductase 0.0024 0.0001 0.0001
Echinococcus granulosus phosphatidylinositol 3 and 4 kinase 0.2779 0.2899 0.2899
Echinococcus multilocularis potassium voltage gated channel subfamily H 0.0156 0.014 0.014
Trichomonas vaginalis fk506-binding protein, putative 0.0114 0.0097 0.0114
Trypanosoma brucei DNA polymerase kappa, putative 0.0121 0.0104 0.0122
Brugia malayi Nuclear hormone receptor family member nhr-25 0.0053 0.0032 0.0036
Echinococcus multilocularis geminin 0.0353 0.0347 0.0347
Toxoplasma gondii ImpB/MucB/SamB family protein 0.0038 0.0016 0.0024
Echinococcus granulosus aldehyde dehydrogenase mitochondrial 0.0184 0.017 0.017
Loa Loa (eye worm) hypothetical protein 0.1538 0.1594 0.1893
Trypanosoma cruzi mitochondrial DNA polymerase beta-PAK, putative 0.0141 0.0125 0.0147
Trypanosoma cruzi phosphatidylinositol 4-kinase, putative 0.0529 0.0533 0.0632
Echinococcus granulosus cpg binding protein 0.0061 0.0041 0.0041
Echinococcus multilocularis histone lysine methyltransferase setb histone lysine methyltransferase eggless 0.0224 0.0212 0.0212
Trichomonas vaginalis AGC family protein kinase 0.0065 0.0045 0.0052
Echinococcus granulosus neutral alpha glucosidase AB 0.0038 0.0016 0.0016
Toxoplasma gondii hypothetical protein 0.0048 0.0027 0.0041
Echinococcus multilocularis GPCR, family 2 0.0257 0.0246 0.0246
Schistosoma mansoni dihydrolipoamide dehydrogenase 0.0089 0.007 0.007
Echinococcus multilocularis lamin 0.022 0.0208 0.0208
Toxoplasma gondii ABC1 family protein 0.0072 0.0052 0.0081
Plasmodium vivax ATP-dependent Clp protease proteolytic subunit, putative 0.0107 0.0088 0.1574
Brugia malayi nuclear receptor NHR-67 0.0025 0.0002 0.0002
Chlamydia trachomatis 3'(2'),5'-bisphosphate nucleotidase CysQ 0.0024 0.0001 0.0012
Trichomonas vaginalis chromobox protein, putative 0.0072 0.0052 0.0061
Leishmania major DNA polymerase kappa, putative 0.0121 0.0104 0.0122
Onchocerca volvulus 0.022 0.0208 0.1126
Trypanosoma cruzi hypothetical protein, conserved 0.0103 0.0085 0.01
Echinococcus multilocularis ferritin 0.0106 0.0087 0.0087
Echinococcus granulosus nervana 2 0.004 0.0019 0.0019
Trichomonas vaginalis PIKK family atypical protein kinase 0.4346 0.4548 0.5405
Trypanosoma brucei glucosidase, putative 0.0038 0.0016 0.0018
Brugia malayi Nuclear hormone receptor family member nhr-14 0.0053 0.0032 0.0036
Schistosoma mansoni lamin 0.022 0.0208 0.0208
Leishmania major DNA polymerase eta, putative 0.0063 0.0043 0.005
Echinococcus multilocularis thioredoxin glutathione reductase 0.0256 0.0246 0.0246
Schistosoma mansoni ferritin 0.0106 0.0087 0.0087
Leishmania major DNA polymerase eta, putative 0.0147 0.0131 0.0154
Echinococcus granulosus sterol regulatory element binding protein 0.0131 0.0114 0.0114
Trypanosoma cruzi phosphatidylinositol 3-kinase, putative 0.0529 0.0533 0.0632
Echinococcus multilocularis guanine nucleotide binding protein G(s) subunit 0.0328 0.0321 0.0321
Trichomonas vaginalis alpha-glucosidase, putative 0.0038 0.0016 0.0018
Toxoplasma gondii FATC domain-containing protein 0.1538 0.1594 0.2543
Echinococcus granulosus voltage gated potassium channel 0.0045 0.0024 0.0024
Loa Loa (eye worm) hypothetical protein 0.0028 0.0006 0.0005
Echinococcus multilocularis Mitotic checkpoint protein PRCC, C terminal 0.0272 0.0262 0.0262
Brugia malayi Steroid receptor seven-up type 2 0.0053 0.0032 0.0036
Echinococcus multilocularis ubiquitin carboxyl terminal hydrolase 8 0.0127 0.011 0.011
Echinococcus granulosus tumor protein p63 0.519 0.5436 0.5436
Mycobacterium leprae possible inositol monophosphatase SubH (IMPase) (inositol-1-phosphatase) (I-1-Pase ). 0.0204 0.0191 0.2886
Brugia malayi Phosphatidylinositol 3- and 4-kinase family protein 0.1538 0.1594 0.1893
Entamoeba histolytica protein kinase, putative 0.0061 0.0041 0.0047
Echinococcus multilocularis histone lysine N methyltransferase SETMAR 0.0224 0.0212 0.0212
Leishmania major dihydrolipoamide dehydrogenase, putative 0.0089 0.007 0.0081
Trichomonas vaginalis alpha-glucosidase, putative 0.0038 0.0016 0.0018
Loa Loa (eye worm) hypothetical protein 0.0028 0.0006 0.0005
Plasmodium falciparum dihydrolipoyl dehydrogenase, mitochondrial 0.0089 0.007 0.1234
Loa Loa (eye worm) nuclear receptor NHR-67 0.0025 0.0002 0.0002
Echinococcus granulosus Smad4 0.0135 0.0119 0.0119
Loa Loa (eye worm) hypothetical protein 0.0048 0.0027 0.003
Giardia lamblia Hypothetical protein 0.0529 0.0533 0.0632
Mycobacterium tuberculosis Probable fatty-acid-CoA ligase FadD7 (fatty-acid-CoA synthetase) (fatty-acid-CoA synthase) 0.0034 0.0012 0.0164
Loa Loa (eye worm) phosphatidylinositol 3 0.0068 0.0048 0.0056
Loa Loa (eye worm) hypothetical protein 0.0095 0.0076 0.0089
Onchocerca volvulus 0.0529 0.0533 0.2896
Brugia malayi MH2 domain containing protein 0.1988 0.2067 0.2456
Echinococcus granulosus Nuclear hormone receptor family member nhr 41 0.0053 0.0032 0.0032
Mycobacterium ulcerans flavoprotein disulfide reductase 0.0089 0.007 0.0134
Echinococcus granulosus Nuclear hormone receptor HR96 0.0025 0.0002 0.0002
Brugia malayi TAR-binding protein 0.0386 0.0382 0.0453
Mycobacterium tuberculosis Probable hydrolase 0.0072 0.0052 0.0774
Loa Loa (eye worm) hypothetical protein 0.0036 0.0014 0.0015
Trypanosoma cruzi mitochondrial DNA polymerase beta-PAK, putative 0.0051 0.003 0.0035
Echinococcus granulosus snurportin 1 0.032 0.0313 0.0313
Schistosoma mansoni hypothetical protein 0.1184 0.1221 0.1221
Mycobacterium ulcerans fatty-acid-CoA ligase 0.0048 0.0027 0.005
Brugia malayi CAAX amino terminal protease family protein 0.0092 0.0073 0.0086
Schistosoma mansoni nuclear receptor nhr-48 0.0025 0.0002 0.0002
Brugia malayi Nuclear hormone receptor family member nhr-19 0.0053 0.0032 0.0036
Echinococcus multilocularis 3'(2'),5' bisphosphate nucleotidase 1 0.0024 0.0001 0.0001
Echinococcus granulosus histone lysine methyltransferase setb 0.0224 0.0212 0.0212
Mycobacterium tuberculosis Probable esterase/lipase LipP 0.0072 0.0052 0.0774
Loa Loa (eye worm) glutaminase 0.4869 0.5099 0.6059
Trypanosoma cruzi phosphatidylinositol 4-kinase, putative 0.0529 0.0533 0.0632
Schistosoma mansoni FTZ-F1 nuclear receptor-like protein 0.0053 0.0032 0.0032
Entamoeba histolytica hypothetical protein 0.1538 0.1594 0.1893
Mycobacterium ulcerans monophosphatase CysQ 0.0024 0.0001 0.0001
Echinococcus multilocularis apoptosis inducing factor 1 mitochondrial 0.0024 0.0001 0.0001
Loa Loa (eye worm) hypothetical protein 0.0045 0.0024 0.0027
Echinococcus granulosus DNA dependent protein kinase catalytic subunit 0.0821 0.0839 0.0839
Trypanosoma brucei phosphatidylinositol 4-kinase, putative 0.0529 0.0533 0.0632
Brugia malayi hypothetical protein 0.0132 0.0115 0.0136
Trichomonas vaginalis chromodomain helicase DNA binding protein, putative 0.0025 0.0002 0.0002
Schistosoma mansoni hypothetical protein 0.0024 0.0001 0.0001
Loa Loa (eye worm) hypothetical protein 0.0092 0.0073 0.0086

Activities

No activities found for this compound.

Phenotypes

Whole-cell/tissue/organism interactions

We have no records of whole-cell/tissue assays done with this compound What does this mean?

Many chemical entities in TDR Targets come from high-throughput screenings with whole cells or tissue samples, and not all assayed compounds have been tested against a single a single target protein, probably because they get ruled out during screening process. Even if these compounds may have not been of interest in the original screening, they may come as interesting leads for other screening assays. Furthermore, we may be able to propose drug-target associations using chemical similarities and network patterns.

Annotated phenotypes:

We have no manually annotated phenotypes for this drug. What does this mean? / Care to help?
In TDR Targets, information about phenotypes that are caused by drugs, or by genetic manipulation of cells (e.g. gene knockouts or knockdowns) is manually curated from the literature. These descriptions help to describe the potential of the target for drug development. If no information is available for this gene or if the information is incomplete, this may mean that i) the papers containing this information either appeared after the curation effort for this organism was carried out or they were inadvertently missed by curators; or that ii) the curation effort for this organism has not yet started.
 
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External resources for this compound

Bibliographic References

No literature references available for this target.

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