Detailed information for compound 1212156

Basic information

Technical information
  • Name: Unnamed compound
  • MW: 441.499 | Formula: C19H27N3O7S
  • H donors: 0 H acceptors: 4 LogP: 0.29 Rotable bonds: 8
    Rule of 5 violations (Lipinski): 1
  • SMILES: COC(CN(C(=O)C1CCCN(C1)S(=O)(=O)c1ccc2c(c1)oc(=O)n2C)C)OC
  • InChi: 1S/C19H27N3O7S/c1-20(12-17(27-3)28-4)18(23)13-6-5-9-22(11-13)30(25,26)14-7-8-15-16(10-14)29-19(24)21(15)2/h7-8,10,13,17H,5-6,9,11-12H2,1-4H3
  • InChiKey: RWFAVTHPHYFIEV-UHFFFAOYSA-N  


Substructure search Similarity search

Network

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Synonyms

No synonyms found for this compound

Targets

Known targets for this compound

No curated genes were found associated with this compound

Predicted pathogen targets for this compound

By orthology
No druggable targets predicted by orthology data
By sequence similarity to non orthologous known druggable targets
No druggable targets predicted by sequence similarity
Obtained from network model

Ranking Plot

Putative Targets List

Species Potential target Raw Global Species
Mycobacterium tuberculosis Probable thioesterase TesA 0.0018 0.0024 0.0041
Trypanosoma cruzi PAB1-binding protein , putative 0.0025 0.0044 0.02
Brugia malayi Papain family cysteine protease containing protein 0.0019 0.0026 0.0061
Onchocerca volvulus Rap guanine nucleotide exchange factor 1 homolog 0.0203 0.0568 0.136
Mycobacterium ulcerans fatty-acid-CoA ligase 0.0023 0.004 0.0065
Brugia malayi Latrophilin receptor protein 2 0.0045 0.0104 0.0251
Schistosoma mansoni cathepsin F (C01 family) 0.0019 0.0026 0.0025
Echinococcus granulosus cathepsin l1 0.0019 0.0026 0.0026
Mycobacterium tuberculosis Probable polyketide synthase Pks5 0.0021 0.0033 0.0062
Loa Loa (eye worm) hypothetical protein 0.0018 0.0022 0.0082
Schistosoma mansoni tar DNA-binding protein 0.0111 0.0299 0.0298
Brugia malayi nuclear receptor NHR-88 0.0019 0.0028 0.0065
Loa Loa (eye worm) hypothetical protein 0.0438 0.1262 0.4603
Toxoplasma gondii isocitrate dehydrogenase 0.0028 0.0052 0.0117
Brugia malayi steroid hormone receptor 0.0019 0.0028 0.0065
Brugia malayi PHD-finger family protein 0.0024 0.004 0.0096
Schistosoma mansoni histone-lysine n-methyltransferase setb1 0.0016 0.0017 0.0016
Loa Loa (eye worm) jmjC domain-containing protein 0.0014 0.0011 0.004
Echinococcus multilocularis neuropeptide s receptor 0.0466 0.1346 0.1346
Trichomonas vaginalis CAMK family protein kinase 0.0106 0.0283 0.0669
Echinococcus multilocularis geminin 0.0148 0.0408 0.0408
Echinococcus multilocularis purine nucleoside phosphorylase 0.094 0.2742 0.2742
Leishmania major 4-coumarate:coa ligase-like protein 0.0023 0.004 0.017
Brugia malayi Hypothetical 52.5 kDa protein ZK945.1 in chromosome II, putative 0.0036 0.0077 0.0185
Loa Loa (eye worm) hypothetical protein 0.0062 0.0153 0.0558
Entamoeba histolytica heat shock transcription factor, putative 0.0087 0.0226 0.0548
Trichomonas vaginalis inositol monophosphatase, putative 0.0037 0.008 0.0175
Onchocerca volvulus Polycomb protein Sfmbt homolog 0.005 0.0118 0.0267
Loa Loa (eye worm) hypothetical protein 0.0078 0.0201 0.0732
Schistosoma mansoni purine nucleoside phosphorylase 0.1409 0.4127 0.4127
Echinococcus multilocularis neuropeptide receptor A26 0.0466 0.1346 0.1346
Echinococcus granulosus geminin 0.0148 0.0408 0.0408
Echinococcus multilocularis zinc finger protein 0.0019 0.0027 0.0027
Mycobacterium tuberculosis Hypothetical protein 0.047 0.1356 0.3275
Echinococcus granulosus methyl CpG binding domain protein 2 0.0015 0.0015 0.0015
Mycobacterium ulcerans fusion of enoyl-CoA hydratase, EchA21 and lipase, LipE 0.0036 0.0077 0.0156
Loa Loa (eye worm) fibroinase 0.0019 0.0026 0.0095
Brugia malayi photoreceptor-specific nuclear receptor 0.0019 0.0028 0.0065
Trypanosoma cruzi Vps23 core domain containing protein, putative 0.0025 0.0044 0.02
Loa Loa (eye worm) beta-LACTamase domain containing family member 0.0036 0.0077 0.0282
Schistosoma mansoni lozenge 0.0049 0.0114 0.0113
Onchocerca volvulus 0.0019 0.0026 0.0044
Schistosoma mansoni nuclear hormone receptor 0.0019 0.0028 0.0027
Mycobacterium ulcerans esterase/lipase LipP 0.0036 0.0077 0.0156
Schistosoma mansoni tsg101-related 0.0065 0.0162 0.0161
Leishmania major tyrosyl-DNA phosphodiesterase 1 0.0058 0.0141 0.0745
Schistosoma mansoni Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) 0.0046 0.0106 0.0105
Loa Loa (eye worm) hypothetical protein 0.0039 0.0086 0.0314
Echinococcus multilocularis guanine nucleotide binding protein G(s) subunit 0.0046 0.0106 0.0106
Loa Loa (eye worm) hypothetical protein 0.0014 0.0011 0.004
Mycobacterium ulcerans thioesterase 0.0018 0.0024 0.0027
Trypanosoma cruzi cysteine peptidase, putative 0.0072 0.0182 0.0982
Loa Loa (eye worm) MBCTL1 0.0057 0.0138 0.0504
Brugia malayi Beta-ketoacyl synthase, N-terminal domain containing protein 0.0022 0.0035 0.0082
Brugia malayi GTP-binding regulatory protein Gs alpha-S chain, putative 0.0046 0.0106 0.0255
Echinococcus multilocularis cpg binding protein 0.0036 0.0076 0.0076
Schistosoma mansoni methylthioadenosine phosphorylase 0.0609 0.1766 0.1765
Echinococcus multilocularis isocitrate dehydrogenase 0.0028 0.0052 0.0052
Trypanosoma brucei apurinic/apyrimidinic endonuclease, putative 0.002 0.0029 0.0111
Schistosoma mansoni ap endonuclease 0.002 0.0029 0.0028
Echinococcus granulosus FTZ F1 alpha 0.0019 0.0028 0.0028
Echinococcus multilocularis NADP dependent isocitrate dehydrogenase 0.0028 0.0052 0.0052
Trichomonas vaginalis CAMK family protein kinase 0.0052 0.0125 0.0285
Echinococcus granulosus importin subunit beta 1 0.0032 0.0066 0.0066
Echinococcus multilocularis methyl CpG binding domain protein 2 0.0015 0.0015 0.0015
Trichomonas vaginalis Clan CA, family C1, papain-like cysteine peptidase 0.0019 0.0026 0.0044
Schistosoma mansoni acetyl-CoA C-acetyltransferase 0.0022 0.0034 0.0033
Mycobacterium tuberculosis Phenyloxazoline synthase MbtB (phenyloxazoline synthetase) 0.0027 0.0051 0.0106
Leishmania major hypothetical protein, conserved 0.0014 0.0011 0.0006
Schistosoma mansoni importin beta-1 0.0032 0.0066 0.0065
Leishmania major cathepsin L-like protease 0.0019 0.0026 0.0091
Entamoeba histolytica hypothetical protein 0.0013 0.0009 0.0004
Loa Loa (eye worm) latrophilin receptor protein 2 0.0045 0.0104 0.0381
Brugia malayi jmjC domain containing protein 0.0014 0.0011 0.0025
Entamoeba histolytica exodeoxyribonuclease III, putative 0.002 0.0029 0.0053
Loa Loa (eye worm) hypothetical protein 0.001 0.0001 0.0003
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0019 0.0026 0.0044
Onchocerca volvulus 0.0054 0.013 0.0297
Mycobacterium tuberculosis Fatty-acid-AMP ligase FadD30 (fatty-acid-AMP synthetase) (fatty-acid-AMP synthase) 0.0018 0.0022 0.0037
Trypanosoma cruzi ISWI complex protein 0.0013 0.001 0.0006
Brugia malayi TAR-binding protein 0.0111 0.0299 0.0722
Plasmodium falciparum acyl-CoA synthetase 0.0018 0.0022 0.0028
Loa Loa (eye worm) beta-lactamase 0.0036 0.0077 0.0282
Onchocerca volvulus Cathepsin F homolog 0.0019 0.0026 0.0044
Onchocerca volvulus Serine\/threonine kinase homolog 0.0106 0.0283 0.0669
Brugia malayi AMP-binding enzyme family protein 0.0023 0.004 0.0095
Echinococcus granulosus inositol monophosphatase 1 0.0037 0.008 0.008
Mycobacterium ulcerans glutaminase 0.0274 0.078 0.1864
Echinococcus granulosus Nuclear hormone receptor family member nhr 41 0.0019 0.0028 0.0028
Plasmodium vivax vivapain-2 0.0019 0.0026 0.0037
Trichomonas vaginalis purine nucleoside phosphorylase, putative 0.047 0.1356 0.3274
Schistosoma mansoni retinoic acid receptor RXR 0.0019 0.0028 0.0027
Toxoplasma gondii histone lysine methyltransferase SET1 0.0063 0.0157 0.0378
Brugia malayi Cathepsin L-like cysteine proteinase 0.0013 0.0008 0.0017
Brugia malayi Nuclear hormone receptor family member nhr-25 0.0019 0.0028 0.0065
Plasmodium vivax vivapain-2 0.0019 0.0026 0.0037
Loa Loa (eye worm) nucleolar RNA-associated protein alpha 0.0345 0.0989 0.3607
Brugia malayi purine nucleoside phosphorylase I, inosine and guanosine-specific family protein 0.1409 0.4127 1
Echinococcus granulosus cathepsin l1 0.0013 0.0008 0.0008
Echinococcus granulosus cathepsin l cysteine peptidase 0.0019 0.0026 0.0026
Onchocerca volvulus Cathepsin L homolog 0.0019 0.0026 0.0044
Trichomonas vaginalis CAMK family protein kinase 0.0106 0.0283 0.0669
Echinococcus granulosus Transcription factor JmjC domain containing protein 0.0051 0.0122 0.0122
Echinococcus granulosus inosine guanosine and xanthosine phosphorylase 0.094 0.2742 0.2742
Trichomonas vaginalis purine nucleoside phosphorylase, putative 0.047 0.1356 0.3274
Mycobacterium ulcerans phenolpthiocerol synthesis type-I polyketide synthase PpsA 0.0018 0.0022 0.0022
Mycobacterium tuberculosis Probable esterase LipL 0.0036 0.0077 0.017
Loa Loa (eye worm) hypothetical protein 0.0019 0.0028 0.0102
Trypanosoma cruzi cysteine peptidase, putative 0.0072 0.0182 0.0982
Mycobacterium tuberculosis Possible conserved lipoprotein LpqK 0.0036 0.0077 0.017
Trypanosoma cruzi hypothetical protein, conserved 0.0036 0.0077 0.0388
Loa Loa (eye worm) hypothetical protein 0.0018 0.0022 0.0082
Brugia malayi RNA binding protein 0.0111 0.0299 0.0722
Trichomonas vaginalis myo inositol monophosphatase, putative 0.0037 0.008 0.0175
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0019 0.0026 0.0044
Mycobacterium leprae possible inositol monophosphatase SubH (IMPase) (inositol-1-phosphatase) (I-1-Pase ). 0.0033 0.0069 0.0135
Brugia malayi oxidoreductase, zinc-binding dehydrogenase family protein 0.0041 0.0092 0.0222
Brugia malayi latrophilin 2 splice variant baaae 0.0098 0.026 0.0628
Entamoeba histolytica cysteine proteinase, putative 0.0019 0.0026 0.0046
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0072 0.0182 0.0982
Echinococcus multilocularis dnaJ subfamily B 0.0459 0.1324 0.1324
Mycobacterium leprae Probable lipase LipE 0.0036 0.0077 0.0156
Mycobacterium tuberculosis Probable polyketide synthase Pks1 0.0016 0.0017 0.0023
Trypanosoma brucei JmjC domain, hydroxylase, putative 0.0014 0.0011 0.0011
Leishmania major methylthioadenosine phosphorylase, putative 0.0609 0.1766 1
Echinococcus granulosus COUP TF:Svp nuclear hormone receptor 0.0019 0.0028 0.0028
Loa Loa (eye worm) hypothetical protein 0.0387 0.1113 0.4061
Trypanosoma cruzi isocitrate dehydrogenase [NADP], mitochondrial precursor, putative 0.0028 0.0052 0.0247
Echinococcus granulosus retinoic acid receptor rxr beta a 0.0019 0.0028 0.0028
Entamoeba histolytica acyl-CoA synthetase, putative 0.0026 0.0046 0.0097
Schistosoma mansoni hypothetical protein 0.0098 0.026 0.0259
Echinococcus multilocularis hepatocyte nuclear factor 4 alpha 0.0019 0.0028 0.0028
Leishmania major cathepsin L-like protease 0.0072 0.0182 0.0977
Echinococcus granulosus FTZ F1 nuclear receptor protein 0.0019 0.0028 0.0028
Giardia lamblia Kinase, PLK 0.0106 0.0283 0.0621
Mycobacterium ulcerans multifunctional mycocerosic acid synthase membrane-associated Mas 0.0023 0.0039 0.0063
Mycobacterium tuberculosis Probable conserved lipoprotein 0.0036 0.0077 0.017
Echinococcus multilocularis purine nucleoside phosphorylase 0.1409 0.4127 0.4127
Entamoeba histolytica hypothetical protein 0.0013 0.0009 0.0004
Brugia malayi hypothetical protein 0.0025 0.0044 0.0105
Brugia malayi Nuclear hormone receptor family member nhr-19 0.0019 0.0028 0.0065
Entamoeba histolytica myo-inositol monophosphatase, putative 0.0037 0.008 0.0181
Brugia malayi hypothetical protein 0.0387 0.1113 0.2696
Toxoplasma gondii phosphorylase family protein 0.047 0.1356 0.3384
Loa Loa (eye worm) hypothetical protein 0.0045 0.0104 0.0381
Loa Loa (eye worm) glutaminase 2 0.0274 0.078 0.2845
Echinococcus multilocularis snurportin 1 0.0345 0.0989 0.0989
Mycobacterium ulcerans bifunctional Mta/Sah nucleosidase Mtn 0.047 0.1356 0.3265
Loa Loa (eye worm) hypothetical protein 0.0036 0.0077 0.0282
Echinococcus multilocularis SAM and MBT domain containing protein 0.005 0.0118 0.0118
Echinococcus multilocularis cathepsin l cysteine peptidase 0.0019 0.0026 0.0026
Mycobacterium ulcerans phenolpthiocerol synthesis type-I polyketide synthase PpsD 0.0022 0.0035 0.0053
Mycobacterium leprae Probable purine nucleoside phosphorylase DeoD (INOSINE PHOSPHORYLASE) (PNP) 0.1409 0.4127 1
Leishmania major hypothetical protein, conserved 0.0036 0.0077 0.0382
Echinococcus multilocularis importin subunit beta 1 0.0032 0.0066 0.0066
Trichomonas vaginalis D-aminoacylase, putative 0.0036 0.0077 0.0169
Toxoplasma gondii isocitrate dehydrogenase 0.0028 0.0052 0.0117
Trichomonas vaginalis purine nucleoside phosphorylase, putative 0.047 0.1356 0.3274
Schistosoma mansoni tsg101-related 0.0053 0.0127 0.0126
Echinococcus granulosus hepatocyte nuclear factor 4 alpha 0.0019 0.0028 0.0028
Schistosoma mansoni cpg binding protein 0.0032 0.0066 0.0065
Trichomonas vaginalis conserved hypothetical protein 0.047 0.1356 0.3274
Schistosoma mansoni methyl-cpg binding protein mbd 0.0015 0.0015 0.0014
Loa Loa (eye worm) hypothetical protein 0.0036 0.0077 0.0282
Toxoplasma gondii beta-ketoacyl synthase, N-terminal domain-containing protein 0.0014 0.0012 0.0016
Mycobacterium leprae PHENOLPTHIOCEROL SYNTHESIS TYPE-I POLYKETIDE SYNTHASE PPSC 0.0023 0.0039 0.0063
Echinococcus multilocularis NADP dependent isocitrate dehydrogenase 0.0028 0.0052 0.0052
Echinococcus multilocularis Transcription factor, JmjC domain containing protein 0.0051 0.0122 0.0122
Echinococcus granulosus tyrosyl DNA phosphodiesterase 1 0.0058 0.0141 0.0141
Schistosoma mansoni nuclear hormone receptor nor-1/nor-2 0.0019 0.0028 0.0027
Echinococcus multilocularis muscleblind protein 0.0438 0.1262 0.1262
Echinococcus granulosus purine nucleoside phosphorylase 0.1409 0.4127 0.4127
Echinococcus granulosus jumonji domain containing 1A 0.0014 0.0011 0.0011
Loa Loa (eye worm) tyrosyl-DNA phosphodiesterase 0.0058 0.0141 0.0514
Echinococcus granulosus bromodomain adjacent to zinc finger domain 0.0054 0.013 0.013
Schistosoma mansoni cathepsin F (C01 family) 0.0019 0.0026 0.0025
Echinococcus granulosus tar DNA binding protein 0.0111 0.0299 0.0299
Loa Loa (eye worm) hypothetical protein 0.001 0.0001 0.0003
Mycobacterium ulcerans beta-lactamase 0.0036 0.0077 0.0156
Echinococcus multilocularis survival motor neuron protein 1 0.0265 0.0753 0.0753
Plasmodium falciparum ataxin-2 like protein, putative 0.0025 0.0044 0.0083
Echinococcus multilocularis endonuclease exonuclease phosphatase 0.0201 0.0562 0.0562
Echinococcus multilocularis cathepsin L cysteine protease 0.0019 0.0026 0.0026
Echinococcus granulosus purine nucleoside phosphorylase 0.1409 0.4127 0.4127
Mycobacterium tuberculosis Polyketide synthase Pks13 0.0033 0.0067 0.0144
Mycobacterium tuberculosis Probable isocitrate dehydrogenase [NADP] Icd1 (oxalosuccinate decarboxylase) (IDH) (NADP+-specific ICDH) (IDP) 0.0028 0.0052 0.011
Brugia malayi Cathepsin L-like precursor 0.0019 0.0026 0.0061
Echinococcus multilocularis cathepsin L cysteine protease 0.0019 0.0026 0.0026
Toxoplasma gondii histone lysine demethylase JMJD6a 0.0014 0.0011 0.0013
Trichomonas vaginalis D-aminoacylase, putative 0.0036 0.0077 0.0169
Plasmodium falciparum ataxin-2 like protein, putative 0.0025 0.0044 0.0083
Loa Loa (eye worm) hypothetical protein 0.094 0.2742 1
Trypanosoma cruzi polo-like protein kinase, putative 0.0106 0.0283 0.156
Giardia lamblia 5-methylthioadenosine nucleosidase, S-adenosylhomocysteine nucleosidase 0.047 0.1356 0.3239
Brugia malayi hypothetical protein 0.0302 0.086 0.2083
Trichomonas vaginalis ap endonuclease, putative 0.002 0.0029 0.0051
Mycobacterium ulcerans polyketide synthase 0.0022 0.0035 0.0053
Trypanosoma brucei hypothetical protein, conserved 0.0036 0.0077 0.0388
Schistosoma mansoni photoreceptor-specific nuclear receptor related 0.0019 0.0028 0.0027
Brugia malayi Steroid receptor seven-up type 2 0.0019 0.0028 0.0065
Trichomonas vaginalis Clan CA, family C1, cathepsin L or K-like cysteine peptidase 0.0019 0.0026 0.0044
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0019 0.0026 0.0044
Loa Loa (eye worm) hypothetical protein 0.0018 0.0022 0.0082
Loa Loa (eye worm) RNA binding protein 0.0111 0.0299 0.1089
Echinococcus multilocularis serine:threonine protein kinase PLK1 0.0106 0.0283 0.0283
Plasmodium falciparum cysteine proteinase falcipain 2b 0.0019 0.0026 0.0037
Loa Loa (eye worm) hypothetical protein 0.0016 0.0017 0.0061
Toxoplasma gondii histone lysine demethylase JMJC1/KDM5D/JARID1D 0.0014 0.0011 0.0013
Onchocerca volvulus 0.0036 0.0077 0.0169
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0072 0.0182 0.0982
Echinococcus multilocularis transcription factor Dp 1 0.0033 0.0069 0.0069
Brugia malayi uridine phosphorylase family protein 0.047 0.1356 0.3285
Schistosoma mansoni methylthioadenosine phosphorylase 0.047 0.1356 0.1356
Echinococcus granulosus SAM and MBT domain containing protein 0.005 0.0118 0.0118
Echinococcus multilocularis methylthioadenosine phosphorylase 0.0609 0.1766 0.1766
Schistosoma mansoni NADP-specific isocitrate dehydrogenase 0.0028 0.0052 0.0052
Echinococcus granulosus histone acetyltransferase MYST2 0.0057 0.0138 0.0138
Echinococcus granulosus snurportin 1 0.0345 0.0989 0.0989
Echinococcus multilocularis uridine phosphorylase 1 0.047 0.1356 0.1356
Brugia malayi Nuclear hormone receptor family member nhr-41 0.0019 0.0028 0.0065
Schistosoma mansoni hypothetical protein 0.0345 0.0989 0.0988
Loa Loa (eye worm) hypothetical protein 0.0019 0.0028 0.0102
Onchocerca volvulus 0.0387 0.1113 0.2684
Echinococcus granulosus beta LACTamase domain containing family member 0.0036 0.0077 0.0077
Trichomonas vaginalis myo inositol monophosphatase, putative 0.0037 0.008 0.0175
Loa Loa (eye worm) mbt repeat family protein 0.005 0.0118 0.043
Loa Loa (eye worm) hypothetical protein 0.0019 0.0028 0.0102
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0019 0.0026 0.0044
Entamoeba histolytica purine nucleoside phosphorylase, putative 0.047 0.1356 0.3381
Echinococcus granulosus uridine phosphorylase 1 0.047 0.1356 0.1356
Echinococcus multilocularis cadherin EGF LAG seven pass G type receptor 0.0045 0.0104 0.0104
Echinococcus multilocularis tyrosyl DNA phosphodiesterase 1 0.0058 0.0141 0.0141
Echinococcus multilocularis purine nucleoside phosphorylase 0.1409 0.4127 0.4127
Loa Loa (eye worm) pigment dispersing factor receptor c 0.0143 0.0394 0.1436
Loa Loa (eye worm) hypothetical protein 0.0302 0.086 0.3138
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0072 0.0182 0.0982
Echinococcus granulosus purine nucleoside phosphorylase 0.1409 0.4127 0.4127
Entamoeba histolytica MTA/SAH nucleosidase, putative 0.047 0.1356 0.3381
Entamoeba histolytica purine nucleoside phosphorylase, putative 0.1365 0.3996 1
Brugia malayi AMP-binding enzyme family protein 0.0027 0.0051 0.0121
Loa Loa (eye worm) hypothetical protein 0.001 0.0001 0.0003
Mycobacterium tuberculosis Probable esterase/lipase LipP 0.0036 0.0077 0.017
Leishmania major cathepsin L-like protease 0.0019 0.0026 0.0091
Mycobacterium tuberculosis Polyketide synthase Pks2 0.0021 0.0033 0.0062
Brugia malayi mbt repeat family protein 0.005 0.0118 0.0283
Trypanosoma brucei importin beta-1 subunit, putative 0.0032 0.0066 0.0324
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0019 0.0026 0.0044
Schistosoma mansoni retinoid-x-receptor (RXR) 0.0019 0.0028 0.0027
Loa Loa (eye worm) nuclear hormone receptor family member nhr-1 0.0019 0.0028 0.0102
Trypanosoma brucei tyrosyl-DNA Phosphodiesterase (Tdp1), putative 0.0058 0.0141 0.075
Trypanosoma cruzi myo-inositol-1(or 4)-monophosphatase 1, putative 0.0037 0.008 0.0403
Mycobacterium tuberculosis Probable purine nucleoside phosphorylase DeoD (inosine phosphorylase) (PNP) 0.1409 0.4127 1
Brugia malayi Nuclear hormone receptor family member nhr-25 0.0019 0.0028 0.0065
Entamoeba histolytica acyl-CoA synthetase, putative 0.0023 0.004 0.0081
Loa Loa (eye worm) hypothetical protein 0.0387 0.1113 0.4061
Entamoeba histolytica tyrosyl-DNA phosphodiesterase, putative 0.0058 0.0141 0.0334
Mycobacterium tuberculosis Probable fatty-acid-CoA ligase FadD3 (fatty-acid-CoA synthetase) (fatty-acid-CoA synthase) 0.0017 0.002 0.003
Trichomonas vaginalis D-aminoacylase, putative 0.0036 0.0077 0.0169
Brugia malayi glutaminase DH11.1 0.0274 0.078 0.1888
Leishmania major importin beta-1 subunit, putative 0.0026 0.0048 0.0216
Mycobacterium ulcerans hypothetical protein 0.0036 0.0077 0.0156
Onchocerca volvulus 0.0019 0.0026 0.0044
Loa Loa (eye worm) hypothetical protein 0.0265 0.0753 0.2746
Trichomonas vaginalis CAMK family protein kinase 0.0106 0.0283 0.0669
Mycobacterium tuberculosis Probable lipase LipE 0.0036 0.0077 0.017
Mycobacterium tuberculosis Probable membrane bound polyketide synthase Pks6 0.0033 0.0067 0.0144
Schistosoma mansoni sex comb on midleg homolog 0.005 0.0118 0.0117
Trypanosoma cruzi cysteine peptidase, putative 0.0019 0.0026 0.0096
Trypanosoma cruzi methylthioadenosine phosphorylase, putative 0.0609 0.1766 1
Mycobacterium ulcerans exodeoxyribonuclease III protein XthA 0.002 0.0029 0.0038
Brugia malayi hypothetical protein 0.0265 0.0753 0.1822
Onchocerca volvulus Steroid hormone receptor family member cnr14 homolog 0.0019 0.0028 0.0049
Schistosoma mansoni hypothetical protein 0.0148 0.0408 0.0407
Trichomonas vaginalis Importin beta-1 subunit, putative 0.0026 0.0048 0.0098
Brugia malayi jmjC domain containing protein 0.0055 0.0133 0.0319
Loa Loa (eye worm) hypothetical protein 0.0019 0.0028 0.0102
Loa Loa (eye worm) hypothetical protein 0.0013 0.0008 0.0028
Mycobacterium tuberculosis Probable hydrolase 0.0036 0.0077 0.017
Entamoeba histolytica heat shock transcription factor, putative 0.0087 0.0226 0.0548
Schistosoma mansoni hypothetical protein 0.0054 0.013 0.0129
Schistosoma mansoni inositol monophosphatase 0.0037 0.008 0.0079
Mycobacterium leprae PROBABLE FATTY-ACID-CoA LIGASE FADD7 (FATTY-ACID-CoA SYNTHETASE) (FATTY-ACID-CoA SYNTHASE) 0.0023 0.004 0.0065
Loa Loa (eye worm) hypothetical protein 0.0038 0.0081 0.0297
Echinococcus multilocularis COUP TF:Svp nuclear hormone receptor 0.0019 0.0028 0.0028
Loa Loa (eye worm) jmjC domain-containing protein 0.0014 0.0011 0.004
Schistosoma mansoni ap endonuclease 0.002 0.0029 0.0028
Echinococcus multilocularis Ataxin 2, N terminal,domain containing protein 0.0011 0.0004 0.0004
Echinococcus granulosus transcription factor Dp 1 0.0033 0.0069 0.0069
Brugia malayi Nuclear hormone receptor family member nhr-1 0.0019 0.0028 0.0065
Mycobacterium ulcerans acyl-CoA synthetase 0.0023 0.004 0.0065
Echinococcus granulosus Ataxin 2 N terminaldomain containing protein 0.0011 0.0004 0.0004
Brugia malayi Nuclear hormone receptor family member nhr-3 0.0019 0.0028 0.0065
Trichomonas vaginalis hypothetical protein 0.0038 0.0083 0.0182
Echinococcus granulosus purine nucleoside phosphorylase 0.1409 0.4127 0.4127
Mycobacterium ulcerans lipase LipD 0.0036 0.0077 0.0156
Trichomonas vaginalis Clan CA, family C1, papain-like cysteine peptidase 0.0019 0.0026 0.0044
Loa Loa (eye worm) nuclear hormone receptor-like 1 0.001 0.0001 0.0003
Brugia malayi exodeoxyribonuclease III family protein 0.002 0.0029 0.0067
Echinococcus granulosus Jumonji AT rich interactive domain 1B 0.0017 0.0021 0.0021
Schistosoma mansoni ubiquitously transcribed sex (X/Y) chromosome tetratricopeptide repeat protein-related 0.0014 0.0011 0.001
Loa Loa (eye worm) GTP-binding regulatory protein Gs alpha-S chain 0.0046 0.0106 0.0387
Onchocerca volvulus 0.0019 0.0026 0.0044
Loa Loa (eye worm) hypothetical protein 0.0023 0.004 0.0145
Plasmodium vivax AP endonuclease (DNA-[apurinic or apyrimidinic site] lyase), putative 0.002 0.0029 0.0044
Leishmania major cathepsin L-like protease 0.0072 0.0182 0.0977
Mycobacterium ulcerans acyl-CoA synthetase 0.0023 0.004 0.0065
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0072 0.0182 0.0982
Trichomonas vaginalis CAMK family protein kinase 0.0106 0.0283 0.0669
Mycobacterium leprae PHENOLPTHIOCEROL SYNTHESIS TYPE-I POLYKETIDE SYNTHASE PPSA 0.0022 0.0035 0.0053
Brugia malayi beta-lactamase family protein 0.0036 0.0077 0.0185
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0072 0.0182 0.0982
Trypanosoma cruzi cruzipain precursor, putative 0.0072 0.0182 0.0982
Brugia malayi isocitrate dehydrogenase 0.0028 0.0052 0.0125
Brugia malayi RNA recognition motif domain containing protein 0.0111 0.0299 0.0722
Treponema pallidum pfs protein (pfs) 0.047 0.1356 0.3346
Echinococcus multilocularis beta LACTamase domain containing family member 0.0036 0.0077 0.0077
Entamoeba histolytica purine nucleoside phosphorylase, putative 0.047 0.1356 0.3381
Echinococcus multilocularis histone acetyltransferase MYST2 0.0057 0.0138 0.0138
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0019 0.0026 0.0044
Trypanosoma cruzi ISWI complex protein 0.0013 0.001 0.0006
Mycobacterium ulcerans phenolpthiocerol synthesis type-I polyketide synthase PpsB 0.0018 0.0022 0.0022
Brugia malayi cathepsin L-like precursor 0.0013 0.0008 0.0017
Loa Loa (eye worm) TAR-binding protein 0.0111 0.0299 0.1089
Schistosoma mansoni tar DNA-binding protein 0.0111 0.0299 0.0298
Schistosoma mansoni histone-lysine n-methyltransferase setb1 0.0016 0.0017 0.0016
Loa Loa (eye worm) steroid hormone receptor 0.0019 0.0028 0.0102
Echinococcus multilocularis cysteine protease 0.0019 0.0026 0.0026
Trypanosoma cruzi nucleoside phosphorylase, putative 0.047 0.1356 0.7668
Loa Loa (eye worm) RNA recognition domain-containing protein domain-containing protein 0.0111 0.0299 0.1089
Toxoplasma gondii type I fatty acid synthase, putative 0.0024 0.0042 0.009
Mycobacterium leprae Probable multifunctional mycocerosic acid synthase membrane associated enzyme Mas 0.0023 0.0039 0.0063
Toxoplasma gondii HEAT repeat-containing protein 0.0032 0.0066 0.0151
Trypanosoma brucei inositol-1(or 4)-monophosphatase 1, putative 0.0037 0.008 0.0403
Trichomonas vaginalis ap endonuclease, putative 0.002 0.0029 0.0051
Echinococcus granulosus methylthioadenosine phosphorylase 0.0609 0.1766 0.1766
Echinococcus granulosus nuclear receptor subfamily 1 group D 0.001 0.0001 0.0001
Trichomonas vaginalis glutaminase, putative 0.0274 0.078 0.1875
Plasmodium falciparum cysteine proteinase falcipain 2a 0.0019 0.0026 0.0037
Schistosoma mansoni coup transcription factor 0.0019 0.0028 0.0027
Mycobacterium leprae PHENOLPTHIOCEROL SYNTHESIS TYPE-I POLYKETIDE SYNTHASE PPSB 0.0018 0.0022 0.0022
Trypanosoma brucei importin beta-1 subunit, putative 0.0032 0.0066 0.0324
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0072 0.0182 0.0982
Trichomonas vaginalis conserved hypothetical protein 0.0013 0.0009 0.0003
Plasmodium vivax importin-beta 2, putative 0.0032 0.0066 0.0138
Schistosoma mansoni family S12 unassigned peptidase (S12 family) 0.0036 0.0077 0.0076
Onchocerca volvulus Fatty acid synthase homolog 0.0039 0.0086 0.0191
Mycobacterium ulcerans Type I modular polyketide synthase 0.0022 0.0035 0.0053
Entamoeba histolytica cysteine proteinase, putative 0.0019 0.0026 0.0046
Brugia malayi Calcitonin receptor-like protein seb-1 0.0143 0.0394 0.0952
Mycobacterium tuberculosis Probable 5'-methylthioadenosine phosphorylase Pnp (MTA phosphorylase) 0.0139 0.038 0.0906
Loa Loa (eye worm) PLK/PLK1 protein kinase 0.0106 0.0283 0.1033
Schistosoma mansoni thyroid hormone receptor 0.0019 0.0028 0.0027
Trichomonas vaginalis CAMK family protein kinase 0.0106 0.0283 0.0669
Entamoeba histolytica hypothetical protein 0.047 0.1356 0.3381
Trichomonas vaginalis purine nucleoside phosphorylase, putative 0.1365 0.3996 0.9681
Leishmania major protein kinase, putative,polo-like protein kinase, putative 0.0106 0.0283 0.1555
Loa Loa (eye worm) hypothetical protein 0.0014 0.0011 0.004
Leishmania major cathepsin L-like protease 0.0019 0.0026 0.0091
Brugia malayi HSF-type DNA-binding domain containing protein 0.0087 0.0226 0.0547
Echinococcus multilocularis purine nucleoside phosphorylase 0.1409 0.4127 0.4127
Echinococcus multilocularis Protein lozenge 0.0049 0.0114 0.0114
Loa Loa (eye worm) hypothetical protein 0.001 0.0001 0.0003
Loa Loa (eye worm) hypothetical protein 0.0019 0.0028 0.0102
Brugia malayi Cathepsin L-like precursor 0.0019 0.0026 0.0061
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0019 0.0026 0.0044
Loa Loa (eye worm) hypothetical protein 0.0018 0.0022 0.0082
Trichomonas vaginalis Clan CA, family C1, papain-like cysteine peptidase 0.0019 0.0026 0.0044
Mycobacterium tuberculosis Phenolpthiocerol synthesis type-I polyketide synthase PpsC 0.0022 0.0035 0.0067
Loa Loa (eye worm) cysteine protease 0.0019 0.0026 0.0095
Mycobacterium tuberculosis Probable fatty-acid-CoA ligase FadD7 (fatty-acid-CoA synthetase) (fatty-acid-CoA synthase) 0.0017 0.002 0.003
Toxoplasma gondii type I fatty acid synthase, putative 0.0016 0.0016 0.0026
Trichomonas vaginalis CAMK family protein kinase 0.0052 0.0125 0.0285
Brugia malayi Bromodomain containing protein 0.0067 0.017 0.0409
Leishmania major cysteine peptidase A (CPA) 0.0019 0.0026 0.0091
Onchocerca volvulus Bile acid receptor homolog 0.0019 0.0028 0.0049
Mycobacterium ulcerans extragenic suppressor protein SuhB 0.0037 0.008 0.0163
Trypanosoma cruzi cysteine peptidase, putative 0.0072 0.0182 0.0982
Brugia malayi serine/threonine-protein kinase plk-2 0.0106 0.0283 0.0684
Plasmodium vivax hypothetical protein, conserved 0.0036 0.0077 0.0166
Brugia malayi Inositol-1 0.0037 0.008 0.0192
Mycobacterium tuberculosis Conserved hypothetical protein 0.047 0.1356 0.3275
Brugia malayi mbt repeat family protein 0.005 0.0118 0.0283
Toxoplasma gondii Purine nucleoside phosphorylase 0.1365 0.3996 1
Schistosoma mansoni tsg101-related 0.0065 0.0162 0.0161
Entamoeba histolytica serine/threonine protein kinase, putative 0.0106 0.0283 0.0691
Loa Loa (eye worm) hypothetical protein 0.0019 0.0028 0.0102
Schistosoma mansoni scm-relatedprotein containing 4 mbt domains (sfmbt) 0.005 0.0118 0.0117
Trichomonas vaginalis purine nucleoside phosphorylase, putative 0.047 0.1356 0.3274
Onchocerca volvulus 0.0036 0.0077 0.0169
Schistosoma mansoni hypothetical protein 0.0018 0.0024 0.0023
Loa Loa (eye worm) nuclear hormone receptor family member nhr-41 0.0019 0.0028 0.0102
Plasmodium vivax purine nucleoside phosphorylase, putative 0.1365 0.3996 1
Entamoeba histolytica purine nucleoside phosphorylase, putative 0.1365 0.3996 1
Loa Loa (eye worm) hypothetical protein 0.0143 0.0394 0.1436
Mycobacterium tuberculosis Phenolpthiocerol synthesis type-I polyketide synthase PpsA 0.0022 0.0035 0.0067
Leishmania major 4-coumarate:coa ligase-like protein 0.0023 0.004 0.017
Echinococcus multilocularis suppression of tumorigenicity 18 protein 0.0057 0.0138 0.0138
Mycobacterium tuberculosis Probable fatty-acid-CoA ligase FadD35 (fatty-acid-CoA synthetase) (fatty-acid-CoA synthase) 0.0017 0.002 0.003
Brugia malayi Nuclear hormone receptor family member nhr-40 0.0019 0.0028 0.0065
Mycobacterium ulcerans long-chain fatty-acid CoA ligase 0.0023 0.004 0.0065
Schistosoma mansoni myelin transcription factor 1 myt1 0.0057 0.0138 0.0137
Brugia malayi AMP-binding enzyme family protein 0.0023 0.004 0.0095
Leishmania major cathepsin L-like protease 0.0019 0.0026 0.0091
Entamoeba histolytica purine nucleoside phosphorylase, putative 0.047 0.1356 0.3381
Loa Loa (eye worm) Papain cysteine protease/cathepsin propeptide inhibitor-containing protein 0.0019 0.0026 0.0095
Brugia malayi Iron-sulfur cluster assembly accessory protein 0.0054 0.013 0.0313
Loa Loa (eye worm) hypothetical protein 0.0019 0.0028 0.0102
Schistosoma mansoni family S12 unassigned peptidase (S12 family) 0.0036 0.0077 0.0076
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0019 0.0026 0.0044
Schistosoma mansoni tar DNA-binding protein 0.0111 0.0299 0.0298
Brugia malayi calcium-independent alpha-latrotoxin receptor 2, putative 0.0045 0.0104 0.0251
Mycobacterium tuberculosis Probable fatty-acid-CoA ligase FadD2 (fatty-acid-CoA synthetase) (fatty-acid-CoA synthase) 0.0023 0.004 0.0079
Echinococcus multilocularis lysine specific demethylase 6a 0.0014 0.0011 0.0011
Leishmania major 4-coumarate:coa ligase-like protein 0.0023 0.004 0.017
Trichomonas vaginalis purine nucleoside phosphorylase I, putative 0.1409 0.4127 1
Brugia malayi Cathepsin L-like precursor 0.0013 0.0008 0.0017
Brugia malayi RNA, U transporter 1 0.0092 0.0242 0.0584
Mycobacterium ulcerans phenolpthiocerol synthesis type-I polyketide synthase PpsC 0.0023 0.0039 0.0063
Echinococcus multilocularis purine nucleoside phosphorylase 0.1409 0.4127 0.4127
Schistosoma mansoni hypothetical protein 0.0148 0.0408 0.0407
Schistosoma mansoni jumonji domain containing protein 0.0014 0.0011 0.001
Leishmania major hypothetical protein, conserved 0.0025 0.0044 0.0194
Schistosoma mansoni mixed-lineage leukemia protein mll 0.0068 0.0172 0.0171
Loa Loa (eye worm) hypothetical protein 0.0025 0.0044 0.0161
Brugia malayi Nuclear hormone receptor family member nhr-14 0.0019 0.0028 0.0065
Loa Loa (eye worm) CXXC zinc finger family protein 0.0032 0.0066 0.0239
Entamoeba histolytica acyl-coA synthetase, putative 0.0023 0.004 0.0081
Echinococcus granulosus nuclear receptor 2DBD gamma 0.0019 0.0028 0.0028
Mycobacterium tuberculosis Probable lipase LipD 0.0036 0.0077 0.017
Mycobacterium tuberculosis Probable fatty-acid-CoA ligase FadD5 (fatty-acid-CoA synthetase) (fatty-acid-CoA synthase) 0.0017 0.002 0.003
Trichomonas vaginalis conserved hypothetical protein 0.047 0.1356 0.3274
Chlamydia trachomatis AMP nucleosidase 0.047 0.1356 1
Schistosoma mansoni glutaminase 0.0274 0.078 0.0779
Echinococcus granulosus suppression of tumorigenicity 18 protein 0.0057 0.0138 0.0138
Brugia malayi AMP-binding enzyme family protein 0.0023 0.004 0.0095
Loa Loa (eye worm) hypothetical protein 0.0023 0.004 0.0145
Echinococcus granulosus lysine specific demethylase 5A 0.0055 0.0133 0.0133
Brugia malayi Bromodomain containing protein 0.0034 0.0069 0.0166
Plasmodium falciparum purine nucleoside phosphorylase 0.1365 0.3996 1
Loa Loa (eye worm) hypothetical protein 0.0057 0.0138 0.0504
Brugia malayi Ligand-binding domain of nuclear hormone receptor family protein 0.0019 0.0028 0.0065
Loa Loa (eye worm) hypothetical protein 0.0019 0.0026 0.0095
Onchocerca volvulus 0.0045 0.0103 0.0231
Echinococcus granulosus nuclear receptor 2DBD gamma 0.0019 0.0028 0.0028
Schistosoma mansoni microtubule-associated protein tau 0.3401 1 1
Onchocerca volvulus Protein ultraspiracle homolog 0.0019 0.0028 0.0049
Echinococcus multilocularis FTZ F1 alpha 0.0019 0.0028 0.0028
Trypanosoma cruzi importin beta-1 subunit, putative 0.0026 0.0048 0.0221
Trichomonas vaginalis purine nucleoside phosphorylase, putative 0.1365 0.3996 0.9681
Brugia malayi Cathepsin L-like precursor 0.0013 0.0008 0.0017
Loa Loa (eye worm) nuclear hormone receptor family member nhr-49 0.0019 0.0028 0.0102
Echinococcus multilocularis tar DNA binding protein 0.0111 0.0299 0.0299
Entamoeba histolytica heat shock transcription factor, putative 0.0087 0.0226 0.0548
Schistosoma mansoni hypothetical protein 0.0013 0.001 0.0009
Leishmania major isocitrate dehydrogenase [NADP], mitochondrial precursor, putative 0.0028 0.0052 0.0241
Onchocerca volvulus 0.0023 0.004 0.0078
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0019 0.0026 0.0044
Brugia malayi Nuclear hormone receptor-like 1 0.0019 0.0028 0.0065
Brugia malayi hypothetical protein 0.0016 0.0018 0.0042
Brugia malayi Importin beta-1 subunit 0.0032 0.0066 0.0158
Trichomonas vaginalis purine nucleoside phosphorylase, putative 0.047 0.1356 0.3274
Echinococcus multilocularis bromodomain adjacent to zinc finger domain 0.0031 0.0063 0.0063
Trypanosoma cruzi isocitrate dehydrogenase, putative 0.0028 0.0052 0.0247
Mycobacterium tuberculosis Probable bifunctional MTA/SAH nucleosidase Mtn: 5'-methylthioadenosine nucleosidase (methylthioadenosine methylthioribohydrolase 0.047 0.1356 0.3275
Trypanosoma cruzi nucleoside phosphorylase, putative 0.047 0.1356 0.7668
Mycobacterium ulcerans thioesterase TesA 0.0018 0.0024 0.0027
Trypanosoma cruzi tyrosyl-DNA Phosphodiesterase (Tdp1), putative 0.0058 0.0141 0.075
Echinococcus multilocularis polycomb protein SCMH1 0.005 0.0118 0.0118
Echinococcus multilocularis nuclear receptor 2DBD gamma 0.0019 0.0028 0.0028
Loa Loa (eye worm) hypothetical protein 0.0036 0.0076 0.0276
Mycobacterium tuberculosis Probable polyketide synthase Pks8 0.0018 0.0023 0.0039
Treponema pallidum purine nucleoside phosphorylase (deoD) 0.1365 0.3996 1
Echinococcus granulosus dnaJ subfamily B 0.0459 0.1324 0.1324
Onchocerca volvulus 0.0019 0.0026 0.0044
Echinococcus multilocularis histone lysine methyltransferase setb histone lysine methyltransferase eggless 0.0016 0.0017 0.0017
Schistosoma mansoni kinase 0.0054 0.0129 0.0129
Schistosoma mansoni hypothetical protein 0.0011 0.0004 0.0003
Echinococcus multilocularis NADP dependent isocitrate dehydrogenase 0.0028 0.0052 0.0052
Loa Loa (eye worm) hypothetical protein 0.0034 0.007 0.0254
Toxoplasma gondii phosphorylase family protein 0.047 0.1356 0.3384
Echinococcus multilocularis GPCR, family 2 0.0045 0.0104 0.0104
Loa Loa (eye worm) hypothetical protein 0.005 0.0118 0.043
Brugia malayi C2-HC type zinc finger protein C.e-MyT1 0.0057 0.0138 0.0333
Loa Loa (eye worm) uridine phosphorylase 0.047 0.1356 0.4947
Echinococcus granulosus phd:f box containing protein 0.0014 0.0011 0.0011
Onchocerca volvulus Heat shock factor protein 2 homolog 0.0087 0.0226 0.0531
Echinococcus granulosus polycomb protein SCMH1 0.005 0.0118 0.0118
Plasmodium falciparum isocitrate dehydrogenase [NADP], mitochondrial 0.0028 0.0052 0.0104
Loa Loa (eye worm) hypothetical protein 0.0014 0.0011 0.004
Trypanosoma cruzi tyrosyl-DNA Phosphodiesterase (Tdp1), putative 0.0058 0.0141 0.075
Echinococcus multilocularis thyroid hormone receptor alpha 0.0019 0.0028 0.0028
Plasmodium vivax isocitrate dehydrogenase [NADP], mitochondrial, putative 0.0028 0.0052 0.0104
Loa Loa (eye worm) nuclear hormone receptor family member nhr-40 0.0019 0.0028 0.0102
Loa Loa (eye worm) hypothetical protein 0.0036 0.0077 0.0282
Loa Loa (eye worm) isocitrate dehydrogenase 0.0028 0.0052 0.0191
Loa Loa (eye worm) jmjC domain-containing protein 0.0055 0.0133 0.0484
Schistosoma mansoni uridine phosphorylase 0.047 0.1356 0.1356
Mycobacterium tuberculosis Conserved protein 0.0036 0.0077 0.017
Mycobacterium ulcerans long-chain-fatty-acid-CoA ligase 0.0023 0.004 0.0065
Schistosoma mansoni hypothetical protein 0.0459 0.1324 0.1323
Schistosoma mansoni Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) 0.0046 0.0106 0.0105
Echinococcus multilocularis nuclear receptor 2DBD gamma 0.0019 0.0028 0.0028
Schistosoma mansoni cathepsin F (C01 family) 0.0013 0.0008 0.0007
Echinococcus granulosus lysine specific demethylase 6a 0.0014 0.0011 0.0011
Schistosoma mansoni Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) 0.0046 0.0106 0.0105
Echinococcus multilocularis fetal alzheimer antigen, falz 0.0022 0.0034 0.0034
Trypanosoma cruzi PAB1-binding protein , putative 0.0025 0.0044 0.02
Echinococcus granulosus neuropeptide receptor A26 0.0466 0.1346 0.1346
Schistosoma mansoni inositol monophosphatase 0.0037 0.008 0.0079
Loa Loa (eye worm) hypothetical protein 0.0036 0.0077 0.0282
Giardia lamblia UPL-1 0.047 0.1356 0.3239
Loa Loa (eye worm) hypothetical protein 0.0019 0.0028 0.0102
Loa Loa (eye worm) glutaminase 0.0274 0.078 0.2845
Trichomonas vaginalis Clan CA, family C1, papain-like cysteine peptidase 0.0019 0.0026 0.0044
Echinococcus multilocularis bromodomain adjacent to zinc finger domain 0.0054 0.013 0.013
Brugia malayi hypothetical protein 0.0078 0.0201 0.0484
Schistosoma mansoni jumonji/arid domain-containing protein 0.0055 0.0133 0.0132
Loa Loa (eye worm) bromodomain containing protein 0.0015 0.0016 0.0059
Schistosoma mansoni serine/threonine protein kinase 0.0106 0.0283 0.0282
Brugia malayi beta-lactamase family protein 0.0036 0.0077 0.0185
Echinococcus multilocularis DNA (apurinic or apyrimidinic site) lyase 0.002 0.0029 0.0029
Echinococcus multilocularis nuclear receptor subfamily 1 group D 0.001 0.0001 0.0001
Mycobacterium tuberculosis Probable exodeoxyribonuclease III protein XthA (exonuclease III) (EXO III) (AP endonuclease VI) 0.002 0.0029 0.0052
Schistosoma mansoni zinc finger protein 0.0019 0.0027 0.0026
Echinococcus multilocularis purine nucleoside phosphorylase 0.1409 0.4127 0.4127
Brugia malayi CXXC zinc finger family protein 0.0032 0.0066 0.0157
Mycobacterium leprae probable uridine phosphorylase 0.047 0.1356 0.3265
Mycobacterium ulcerans polyketide synthase Pks13 0.0033 0.0067 0.013
Loa Loa (eye worm) hypothetical protein 0.0036 0.0077 0.0282
Schistosoma mansoni sex comb on midleg homolog 0.005 0.0118 0.0117
Echinococcus granulosus NADP dependent isocitrate dehydrogenase 0.0028 0.0052 0.0052
Mycobacterium ulcerans Type I modular polyketide synthase 0.0022 0.0035 0.0053
Brugia malayi Ligand-binding domain of nuclear hormone receptor family protein 0.0019 0.0028 0.0065
Wolbachia endosymbiont of Brugia malayi fructose-1,6-bisphosphatase 0.0037 0.008 1
Trichomonas vaginalis penicillin-binding protein, putative 0.0036 0.0077 0.0169
Echinococcus granulosus GPCR family 2 0.0045 0.0104 0.0104
Toxoplasma gondii inositol(myo)-1(or 4)-monophosphatase 2, putative 0.0037 0.008 0.0186
Trypanosoma cruzi nucleoside phosphorylase, putative 0.047 0.1356 0.7668
Echinococcus granulosus purine nucleoside phosphorylase 0.1409 0.4127 0.4127
Leishmania major myo-inositol-1(or 4)-monophosphatase 1, putative 0.0037 0.008 0.0398
Brugia malayi jmjC domain containing protein 0.0051 0.0122 0.0294
Schistosoma mansoni methyl-cpg binding protein mbd 0.0015 0.0015 0.0014
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0072 0.0182 0.0982
Echinococcus multilocularis cysteine protease 0.0019 0.0026 0.0026
Entamoeba histolytica hypothetical protein 0.0026 0.0048 0.0101
Leishmania major nucleoside phosphorylase-like protein 0.047 0.1356 0.7667
Echinococcus multilocularis muscleblind protein 1 0.0438 0.1262 0.1262
Trypanosoma cruzi polo-like protein kinase, putative 0.0106 0.0283 0.156
Plasmodium vivax acyl-CoA synthetase, putative 0.0018 0.0022 0.0028
Trichomonas vaginalis esterase, putative 0.0036 0.0077 0.0169
Schistosoma mansoni tyrosyl-DNA phosphodiesterase 0.0058 0.0141 0.014
Mycobacterium ulcerans purine nucleoside phosphorylase 0.1409 0.4127 1
Loa Loa (eye worm) S-methyl-5'-thioadenosine phosphorylase MTAP 0.0609 0.1766 0.6442
Brugia malayi Muscleblind-like protein 0.0438 0.1262 0.3056
Entamoeba histolytica hypothetical protein 0.0013 0.0009 0.0004
Schistosoma mansoni hypothetical protein 0.0045 0.0104 0.0104
Mycobacterium leprae PROBABLE FATTY-ACID-CoA LIGASE FADD2 (FATTY-ACID-CoA SYNTHETASE) (FATTY-ACID-CoA SYNTHASE) 0.0023 0.004 0.0065
Brugia malayi jmjC domain containing protein 0.0014 0.0011 0.0025
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0072 0.0182 0.0982
Echinococcus granulosus cathepsin L cysteine proteinase 0.0019 0.0026 0.0026
Trichomonas vaginalis Importin beta-1 subunit, putative 0.0026 0.0048 0.0098
Schistosoma mansoni hypothetical protein 0.0045 0.0104 0.0104
Mycobacterium ulcerans long-chain-fatty-acid--CoA ligase 0.0023 0.004 0.0065
Onchocerca volvulus 0.0019 0.0026 0.0044
Trichomonas vaginalis conserved hypothetical protein 0.0013 0.0009 0.0003
Trypanosoma cruzi methylthioadenosine phosphorylase, putative 0.0609 0.1766 1
Trichomonas vaginalis Clan CA, family C1, papain-like cysteine peptidase 0.0019 0.0026 0.0044
Trypanosoma cruzi major cysteine proteinase, putative 0.0056 0.0136 0.0725
Schistosoma mansoni jumonji/arid domain-containing protein 0.0055 0.0133 0.0132
Plasmodium falciparum AP endonuclease (DNA-[apurinic or apyrimidinic site] lyase), putative 0.002 0.0029 0.0044
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0072 0.0182 0.0982
Plasmodium falciparum cysteine proteinase falcipain 3 0.0019 0.0026 0.0037
Loa Loa (eye worm) hypothetical protein 0.0013 0.0008 0.0028
Brugia malayi Corticotropin releasing factor receptor 2 precursor, putative 0.0143 0.0394 0.0952
Mycobacterium ulcerans acyl-CoA synthetase 0.0023 0.004 0.0065
Echinococcus granulosus histone lysine methyltransferase setb 0.0016 0.0017 0.0017
Mycobacterium leprae PROBABLE THIOESTERASE TESA 0.0018 0.0024 0.0027
Trypanosoma brucei Vps23 core domain containing protein, putative 0.0025 0.0044 0.02
Echinococcus granulosus cadherin EGF LAG seven pass G type receptor 0.0045 0.0104 0.0104
Schistosoma mansoni phosphatidylserine receptor 0.0014 0.0011 0.001
Onchocerca volvulus Purine nucleoside phosphorylase homolog 0.1409 0.4127 1
Onchocerca volvulus 0.0302 0.086 0.207
Brugia malayi MTAP 0.0609 0.1766 0.4278
Brugia malayi ecdysteroid receptor 0.0019 0.0028 0.0065
Toxoplasma gondii LsmAD domain-containing protein 0.0025 0.0044 0.0096
Onchocerca volvulus 0.005 0.0118 0.0267
Brugia malayi nuclear hormone receptor 0.0019 0.0028 0.0065
Mycobacterium leprae Probable polyketide synthase Pks1 0.0023 0.0039 0.0063
Onchocerca volvulus 0.0019 0.0026 0.0044
Brugia malayi N-terminal motif family protein 0.0203 0.0568 0.1374
Onchocerca volvulus 0.0019 0.0028 0.0049
Loa Loa (eye worm) exodeoxyribonuclease III family protein 0.002 0.0029 0.0105
Loa Loa (eye worm) hypothetical protein 0.0203 0.0568 0.2071
Loa Loa (eye worm) nuclear hormone receptor family member nhr-14 0.0019 0.0028 0.0102
Loa Loa (eye worm) runx1 0.0049 0.0114 0.0416
Loa Loa (eye worm) hypothetical protein 0.0438 0.1262 0.4603
Toxoplasma gondii cathepsin CPL 0.0019 0.0026 0.005
Echinococcus granulosus muscleblind protein 0.0438 0.1262 0.1262
Schistosoma mansoni purine nucleoside phosphorylase 0.1409 0.4127 0.4127
Loa Loa (eye worm) jmjC domain-containing protein 0.0014 0.0011 0.004
Trichomonas vaginalis penicillin-binding protein, putative 0.0036 0.0077 0.0169
Brugia malayi Nuclear hormone receptor family member nhr-19 0.0019 0.0028 0.0065
Schistosoma mansoni steroid hormone receptor ad4bp 0.0019 0.0028 0.0027
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0019 0.0026 0.0044
Echinococcus granulosus bromodomain adjacent to zinc finger domain 0.0031 0.0063 0.0063
Giardia lamblia Purine nucleoside phosphorylase lateral transfer candidate 0.1409 0.4127 1
Mycobacterium ulcerans polyketide synthase 0.0023 0.0039 0.0063
Schistosoma mansoni tar DNA-binding protein 0.0111 0.0299 0.0298
Loa Loa (eye worm) hypothetical protein 0.0036 0.0077 0.0282
Mycobacterium tuberculosis Inositol-1-monophosphatase SuhB 0.0033 0.0069 0.0149
Loa Loa (eye worm) hypothetical protein 0.0023 0.004 0.0145
Entamoeba histolytica cysteine protease, putative 0.0019 0.0026 0.0046
Mycobacterium tuberculosis Polyketide synthase Pks12 0.0023 0.0039 0.0077
Brugia malayi beta-lactamase 0.0036 0.0077 0.0185
Mycobacterium ulcerans fatty-acid-CoA ligase 0.0018 0.0022 0.0023
Echinococcus multilocularis phd:f box containing protein 0.0014 0.0011 0.0011
Schistosoma mansoni RAR-like nuclear receptor 0.0019 0.0028 0.0027
Loa Loa (eye worm) papain family cysteine protease containing protein 0.0019 0.0026 0.0095
Echinococcus granulosus purine nucleoside phosphorylase 0.1409 0.4127 0.4127
Onchocerca volvulus Cathepsin L homolog 0.0019 0.0026 0.0044
Echinococcus granulosus zinc finger protein 0.0019 0.0027 0.0027
Echinococcus granulosus serine:threonine protein kinase PLK1 0.0106 0.0283 0.0283
Brugia malayi Cathepsin L-like precursor 0.0019 0.0026 0.0061
Treponema pallidum uridine phosphorylase (udp) 0.1365 0.3996 1
Mycobacterium tuberculosis Conserved protein 0.0036 0.0077 0.017
Leishmania major cathepsin L-like protease 0.0019 0.0026 0.0091
Brugia malayi Nuclear hormone receptor family member nhr-49 0.0019 0.0028 0.0065
Onchocerca volvulus 0.0036 0.0077 0.0169
Mycobacterium leprae conserved hypothetical protein 0.0036 0.0077 0.0156
Schistosoma mansoni zinc finger protein 0.0013 0.001 0.0009
Echinococcus multilocularis isocitrate dehydrogenase 2 (NADP+) 0.0028 0.0052 0.0052
Trichomonas vaginalis Clan CA, family C1, cathepsin L or K-like cysteine peptidase 0.0019 0.0026 0.0044
Mycobacterium tuberculosis Conserved protein 0.0036 0.0077 0.017
Schistosoma mansoni protein phosphatase 2C 0.0014 0.0011 0.001
Leishmania major apurinic/apyrimidinic endonuclease-redox protein 0.002 0.0029 0.0106
Trichomonas vaginalis Clan CA, family C1, papain-like cysteine peptidase 0.0019 0.0026 0.0044
Echinococcus multilocularis cathepsin l cysteine peptidase 0.0019 0.0026 0.0026
Loa Loa (eye worm) ctsf protein 0.0019 0.0026 0.0095
Trypanosoma brucei uridine phosphorylase 0.047 0.1356 0.7668
Schistosoma mansoni cpg binding protein 0.0036 0.0076 0.0075
Trypanosoma brucei polo-like protein kinase 0.0106 0.0283 0.156
Echinococcus multilocularis lysine specific demethylase 5A 0.0051 0.0122 0.0122
Trypanosoma cruzi hypothetical protein, conserved 0.0036 0.0077 0.0388
Brugia malayi jmjC domain containing protein 0.0014 0.0011 0.0025
Echinococcus granulosus cpg binding protein 0.0036 0.0076 0.0076
Loa Loa (eye worm) nuclear hormone receptor family member nhr-31 0.0019 0.0028 0.0102
Schistosoma mansoni FTZ-F1 nuclear receptor-like protein 0.0019 0.0028 0.0027
Schistosoma mansoni uridine phosphorylase 0.047 0.1356 0.1356
Echinococcus granulosus neuropeptide s receptor 0.0466 0.1346 0.1346
Echinococcus granulosus tumor susceptibility gene 101 protein 0.0078 0.0201 0.0201
Loa Loa (eye worm) inositol-1 0.0037 0.008 0.0292
Brugia malayi jmjC domain containing protein 0.0014 0.0011 0.0025
Schistosoma mansoni methylthioadenosine phosphorylase 0.0609 0.1766 0.1765
Onchocerca volvulus 0.0027 0.0051 0.0105
Trichomonas vaginalis Clan CA, family C1, papain-like cysteine peptidase 0.0019 0.0026 0.0044
Mycobacterium leprae Polyketide synthase Pks13 0.0033 0.0067 0.013
Brugia malayi Isocitrate dehydrogenase 0.0028 0.0052 0.0125
Echinococcus granulosus DNA apurinic or apyrimidinic site lyase 0.002 0.0029 0.0029
Brugia malayi Nuclear hormone receptor family member nhr-31 0.0019 0.0028 0.0065
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0019 0.0026 0.0044
Loa Loa (eye worm) PHD-finger family protein 0.0018 0.0024 0.0087
Toxoplasma gondii exonuclease III APE 0.002 0.0029 0.0057
Trypanosoma brucei PAB1-binding protein , putative 0.0025 0.0044 0.02
Echinococcus multilocularis ecdysone induced protein 78C 0.0019 0.0028 0.0028
Echinococcus granulosus survival motor neuron protein 1 0.0265 0.0753 0.0753
Loa Loa (eye worm) hypothetical protein 0.001 0.0001 0.0003
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0019 0.0026 0.0044
Echinococcus multilocularis jumonji domain containing 1A 0.0014 0.0011 0.0011
Echinococcus multilocularis Jumonji, AT rich interactive domain 1B 0.0017 0.0021 0.0021
Toxoplasma gondii ABC1 family protein 0.0036 0.0077 0.0179
Trypanosoma cruzi apurinic/apyrimidinic endonuclease 0.002 0.0029 0.0111
Echinococcus granulosus ecdysone induced protein 78C 0.0019 0.0028 0.0028
Brugia malayi Cathepsin L-like precursor 0.0019 0.0026 0.0061
Echinococcus granulosus JmjC domain containing protein 4 0.0014 0.0011 0.0011
Schistosoma mansoni thyroid hormone receptor 0.0019 0.0028 0.0027
Schistosoma mansoni jumonji domain containing protein 0.0051 0.0122 0.0121
Loa Loa (eye worm) hypothetical protein 0.0012 0.0007 0.0024
Echinococcus granulosus fetal alzheimer antigen falz 0.0022 0.0034 0.0034
Brugia malayi Cathepsin L-like precursor 0.0019 0.0026 0.0061
Echinococcus granulosus guanine nucleotide binding protein Gs subunit 0.0046 0.0106 0.0106
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0019 0.0026 0.0044
Loa Loa (eye worm) hypothetical protein 0.0013 0.0008 0.0028
Mycobacterium tuberculosis Probable chain -fatty-acid-CoA ligase FadD13 (fatty-acyl-CoA synthetase) 0.0023 0.004 0.0079
Loa Loa (eye worm) hypothetical protein 0.0018 0.0022 0.0082
Trypanosoma cruzi cysteine peptidase, clan CA, family C1, cathepsin L-like, putative 0.0065 0.0163 0.0878
Trypanosoma brucei ISWI complex protein 0.0013 0.001 0.0006
Mycobacterium ulcerans Type I modular polyketide synthase 0.0022 0.0035 0.0053
Echinococcus multilocularis tumor susceptibility gene 101 protein 0.0078 0.0201 0.0201
Mycobacterium leprae PHENOLPTHIOCEROL SYNTHESIS TYPE-I POLYKETIDE SYNTHASE PPSD 0.0022 0.0035 0.0053
Loa Loa (eye worm) hypothetical protein 0.0032 0.0066 0.0241
Echinococcus granulosus diuretic hormone 44 receptor GPRdih2 0.0045 0.0104 0.0104
Schistosoma mansoni hypothetical protein 0.0045 0.0104 0.0104
Echinococcus multilocularis FTZ F1 nuclear receptor protein 0.0019 0.0028 0.0028
Echinococcus multilocularis JmjC domain containing protein 4 0.0014 0.0011 0.0011
Loa Loa (eye worm) fatty acid synthase 0.0021 0.0034 0.0124
Echinococcus multilocularis inositol monophosphatase 1 0.0037 0.008 0.008
Plasmodium vivax ataxin-2 like protein, putative 0.0025 0.0044 0.0083
Echinococcus multilocularis purine nucleoside phosphorylase 0.094 0.2742 0.2742
Loa Loa (eye worm) nuclear Hormone Receptor family member 0.0019 0.0028 0.0102
Echinococcus multilocularis Nuclear hormone receptor family member nhr 41 0.0019 0.0028 0.0028
Giardia lamblia 5-methylthioadenosine nucleosidase, S-adenosylhomocysteine nucleosidase 0.047 0.1356 0.3239
Schistosoma mansoni cpg binding protein 0.0036 0.0076 0.0075
Leishmania major cathepsin L-like protease 0.0072 0.0182 0.0977
Schistosoma mansoni Tr4/Tr2 (homologue) 0.0019 0.0028 0.0027
Brugia malayi Cathepsin L-like precursor 0.0019 0.0026 0.0061
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0019 0.0026 0.0044
Trichomonas vaginalis CAMK family protein kinase 0.0106 0.0283 0.0669
Loa Loa (eye worm) hypothetical protein 0.0098 0.026 0.0948
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0072 0.0182 0.0982
Mycobacterium tuberculosis Possible penicillin-binding protein 0.0231 0.0652 0.1564
Mycobacterium tuberculosis Phenolpthiocerol synthesis type-I polyketide synthase PpsD 0.0022 0.0035 0.0067
Leishmania major hypothetical protein, conserved 0.0025 0.0044 0.0195
Echinococcus multilocularis purine nucleoside phosphorylase 0.1409 0.4127 0.4127
Schistosoma mansoni hypothetical protein 0.0307 0.0877 0.0877
Mycobacterium ulcerans 5'-methylthioadenosine phosphorylase 0.0609 0.1766 0.4261
Trypanosoma brucei isocitrate dehydrogenase [NADP], mitochondrial precursor, putative 0.0028 0.0052 0.0247
Mycobacterium tuberculosis Probable polyketide synthase Pks7 0.0023 0.0039 0.0077
Trypanosoma brucei isocitrate dehydrogenase, putative 0.0028 0.0052 0.0247
Trichomonas vaginalis CAMK family protein kinase 0.0106 0.0283 0.0669
Schistosoma mansoni phd/f-box containing protein 0.0014 0.0011 0.001
Echinococcus granulosus purine nucleoside phosphorylase 0.1409 0.4127 0.4127
Brugia malayi F/Y-rich N-terminus family protein 0.0012 0.0005 0.0009
Trichomonas vaginalis Clan CA, family C1, papain-like cysteine peptidase 0.0019 0.0026 0.0044
Schistosoma mansoni bromodomain containing protein 0.0057 0.0139 0.0138
Onchocerca volvulus 0.0032 0.0066 0.0141
Schistosoma mansoni nuclear receptor 2DBD-gamma 0.0019 0.0028 0.0027
Schistosoma mansoni tar DNA-binding protein 0.0111 0.0299 0.0298
Trypanosoma cruzi JmjC domain, hydroxylase, putative 0.0014 0.0011 0.0011
Echinococcus granulosus guanine nucleotide binding protein Gs subunit 0.0046 0.0106 0.0106
Echinococcus multilocularis microtubule associated protein 2 0.3401 1 1
Schistosoma mansoni hypothetical protein 0.0045 0.0104 0.0104
Echinococcus multilocularis guanine nucleotide binding protein G(s) subunit 0.0046 0.0106 0.0106
Trypanosoma cruzi JmjC domain, hydroxylase, putative 0.0014 0.0011 0.0011
Trichomonas vaginalis importin beta-1, putative 0.0026 0.0048 0.0098
Mycobacterium ulcerans hypothetical protein 0.0023 0.004 0.0065
Trypanosoma cruzi apurinic/apyrimidinic endonuclease, putative 0.002 0.0029 0.0111
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0072 0.0182 0.0982
Echinococcus granulosus endonuclease exonuclease phosphatase 0.0201 0.0562 0.0562
Loa Loa (eye worm) AMP-binding enzyme family protein 0.0027 0.0051 0.0186
Entamoeba histolytica tumor susceptibility gene 101 protein, putative 0.0053 0.0127 0.0299
Echinococcus multilocularis diuretic hormone 44 receptor GPRdih2 0.0045 0.0104 0.0104
Entamoeba histolytica hypothetical protein 0.0013 0.0009 0.0004
Echinococcus granulosus purine nucleoside phosphorylase 0.1409 0.4127 0.4127
Mycobacterium tuberculosis Probable multifunctional mycocerosic acid synthase membrane-associated Mas 0.0023 0.0039 0.0077
Brugia malayi Tyrosyl-DNA phosphodiesterase family protein 0.0058 0.0141 0.0339
Onchocerca volvulus 0.0019 0.0026 0.0044
Loa Loa (eye worm) hypothetical protein 0.0087 0.0226 0.0826
Trypanosoma brucei methylthioadenosine phosphorylase, putative 0.0609 0.1766 1
Schistosoma mansoni survival motor neuron protein 0.0054 0.013 0.0129
Trichomonas vaginalis Clan CA, family C1, papain-like cysteine peptidase 0.0019 0.0026 0.0044
Plasmodium falciparum importin beta, putative 0.0032 0.0066 0.0138
Trypanosoma cruzi myo-inositol-1(or 4)-monophosphatase 1, putative 0.0037 0.008 0.0403

Activities

Activity type Activity value Assay description Source Reference
AC50 (functional) = 27.333 uM PUBCHEM_BIOASSAY: Bacterial Growth Inhibition Counterscreen using BacTiter-Glo Measured in Microorganism System Using Plate Reader - 2093-02_Inhibitor_Dose_CherryPick_Activity. (Class of assay: confirmatory) [Related pubchem assays (depositor defined):AID488938] ChEMBL. No reference
Potency (functional) 14.7157 uM PUBCHEM_BIOASSAY: Primary qHTS for delayed death inhibitors of the malarial parasite plastid, 96 hour incubation. (Class of assay: confirmatory) [Related pubchem assays (depositor defined):AID488745, AID488752, AID488774, AID504848, AID504850] ChEMBL. No reference
Potency (functional) 28.1838 uM PubChem BioAssay. qHTS of GLP-1 Receptor Inverse Agonists (Inhibition Mode). (Class of assay: confirmatory) ChEMBL. No reference
Potency (functional) 89.1251 uM PUBCHEM_BIOASSAY: qHTS Assay for the Inhibitors of Human Flap endonuclease 1 (FEN1). (Class of assay: confirmatory) [Related pubchem assays (depositor defined):AID488813] ChEMBL. No reference

Phenotypes

Whole-cell/tissue/organism interactions

Species name Source Reference Is orphan
Plasmodium falciparum ChEMBL23

Many chemical entities in TDR Targets come from high-throughput screenings with whole cells or tissue samples, and not all assayed compounds have been tested against a single a single target protein, probably because they get ruled out during screening process. Even if these compounds may have not been of interest in the original screening, they may come as interesting leads for other screening assays. Furthermore, we may be able to propose drug-target associations using chemical similarities and network patterns.

Annotated phenotypes:

We have no manually annotated phenotypes for this drug. What does this mean? / Care to help?
In TDR Targets, information about phenotypes that are caused by drugs, or by genetic manipulation of cells (e.g. gene knockouts or knockdowns) is manually curated from the literature. These descriptions help to describe the potential of the target for drug development. If no information is available for this gene or if the information is incomplete, this may mean that i) the papers containing this information either appeared after the curation effort for this organism was carried out or they were inadvertently missed by curators; or that ii) the curation effort for this organism has not yet started.
 
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External resources for this compound

Bibliographic References

No literature references available for this target.

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