Detailed information for compound 1275797

Basic information

Technical information
  • TDR Targets ID: 1275797
  • Name: Oprea1_143899
  • MW: 235.279 | Formula: C13H17NO3
  • H donors: 1 H acceptors: 2 LogP: 2.35 Rotable bonds: 5
    Rule of 5 violations (Lipinski): 1
  • SMILES: COC(=O)c1cccc(c1)NC(=O)C(C)(C)C
  • InChi: 1S/C13H17NO3/c1-13(2,3)12(16)14-10-7-5-6-9(8-10)11(15)17-4/h5-8H,1-4H3,(H,14,16)
  • InChiKey: OFPQATZPMZQELJ-UHFFFAOYSA-N  


Substructure search Similarity search

Network

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Synonyms

  • SMR000457842
  • methyl 3-[(2,2-dimethylpropanoyl)amino]benzoate
  • MLS000851399
  • ST5445147
  • ZINC00143465
  • IDI1_012644
  • Maybridge3_001257

Targets

Known targets for this compound

Species Target name Source Bibliographic reference
Homo sapiens GNAS complex locus Starlite/ChEMBL No references
Homo sapiens APEX nuclease (multifunctional DNA repair enzyme) 1 Starlite/ChEMBL No references

Predicted pathogen targets for this compound

By orthology
Species Potential target Known druggable target/s Ortholog Group
Schistosoma japonicum DNA-(apurinic or apyrimidinic site) lyase 2, putative Get druggable targets OG5_126768 All targets in OG5_126768
Brugia malayi GTP-binding regulatory protein Gs alpha-S chain, putative Get druggable targets OG5_131088 All targets in OG5_131088
Echinococcus multilocularis DNA (apurinic or apyrimidinic site) lyase Get druggable targets OG5_126768 All targets in OG5_126768
Loa Loa (eye worm) GTP-binding regulatory protein Gs alpha-S chain Get druggable targets OG5_131088 All targets in OG5_131088
Neospora caninum hypothetical protein Get druggable targets OG5_126768 All targets in OG5_126768
Echinococcus granulosus guanine nucleotide binding protein Gs subunit Get druggable targets OG5_131088 All targets in OG5_131088
Brugia malayi exodeoxyribonuclease III family protein Get druggable targets OG5_126768 All targets in OG5_126768
Schistosoma japonicum ko:K10772 AP endonuclease 2, putative Get druggable targets OG5_126768 All targets in OG5_126768
Trypanosoma cruzi apurinic/apyrimidinic endonuclease Get druggable targets OG5_126768 All targets in OG5_126768
Leishmania braziliensis apurinic/apyrimidinic endonuclease-redox protein Get druggable targets OG5_126768 All targets in OG5_126768
Schistosoma japonicum ko:K10771 AP endonuclease 1, putative Get druggable targets OG5_126768 All targets in OG5_126768
Plasmodium knowlesi AP endonuclease (DNA-[apurinic or apyrimidinic site] lyase), putative Get druggable targets OG5_126768 All targets in OG5_126768
Mycobacterium tuberculosis Probable exodeoxyribonuclease III protein XthA (exonuclease III) (EXO III) (AP endonuclease VI) Get druggable targets OG5_126768 All targets in OG5_126768
Schistosoma mansoni ap endonuclease Get druggable targets OG5_126768 All targets in OG5_126768
Theileria parva hypothetical protein Get druggable targets OG5_126768 All targets in OG5_126768
Plasmodium falciparum AP endonuclease (DNA-[apurinic or apyrimidinic site] lyase), putative Get druggable targets OG5_126768 All targets in OG5_126768
Trypanosoma brucei apurinic/apyrimidinic endonuclease, putative Get druggable targets OG5_126768 All targets in OG5_126768
Entamoeba histolytica exodeoxyribonuclease III, putative Get druggable targets OG5_126768 All targets in OG5_126768
Schistosoma mansoni Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) Get druggable targets OG5_131088 All targets in OG5_131088
Echinococcus multilocularis guanine nucleotide binding protein G(s) subunit Get druggable targets OG5_131088 All targets in OG5_131088
Loa Loa (eye worm) exodeoxyribonuclease III family protein Get druggable targets OG5_126768 All targets in OG5_126768
Candida albicans similar to S. cerevisiae APN2 (YBL019W) DNA repair apurinic/apyrimidinic endonuclease Get druggable targets OG5_126768 All targets in OG5_126768
Echinococcus granulosus guanine nucleotide binding protein Gs subunit Get druggable targets OG5_131088 All targets in OG5_131088
Candida albicans similar to S. cerevisiae APN2 (YBL019W) DNA repair apurinic/apyrimidinic endonuclease Get druggable targets OG5_126768 All targets in OG5_126768
Cryptosporidium hominis dna-(apurinic or apyrimidinic site) lyase Get druggable targets OG5_126768 All targets in OG5_126768
Trichomonas vaginalis ap endonuclease, putative Get druggable targets OG5_126768 All targets in OG5_126768
Leishmania donovani apurinic/apyrimidinic endonuclease-redox protein Get druggable targets OG5_126768 All targets in OG5_126768
Mycobacterium ulcerans exodeoxyribonuclease III protein XthA Get druggable targets OG5_126768 All targets in OG5_126768
Trypanosoma congolense apurinic/apyrimidinic endonuclease, putative Get druggable targets OG5_126768 All targets in OG5_126768
Leishmania mexicana apurinic/apyrimidinic endonuclease-redox protein,AP-endonuclease Get druggable targets OG5_126768 All targets in OG5_126768
Wolbachia endosymbiont of Brugia malayi exonuclease III Get druggable targets OG5_126768 All targets in OG5_126768
Echinococcus multilocularis guanine nucleotide binding protein G(s) subunit Get druggable targets OG5_131088 All targets in OG5_131088
Plasmodium berghei AP endonuclease (DNA-[apurinic or apyrimidinic site] lyase), putative Get druggable targets OG5_126768 All targets in OG5_126768
Trypanosoma brucei gambiense apurinic/apyrimidinic endonuclease, putative Get druggable targets OG5_126768 All targets in OG5_126768
Treponema pallidum exodeoxyribonuclease (exoA) Get druggable targets OG5_126768 All targets in OG5_126768
Leishmania infantum apurinic/apyrimidinic endonuclease-redox protein Get druggable targets OG5_126768 All targets in OG5_126768
Leishmania major apurinic/apyrimidinic endonuclease-redox protein Get druggable targets OG5_126768 All targets in OG5_126768
Trichomonas vaginalis ap endonuclease, putative Get druggable targets OG5_126768 All targets in OG5_126768
Plasmodium vivax AP endonuclease (DNA-[apurinic or apyrimidinic site] lyase), putative Get druggable targets OG5_126768 All targets in OG5_126768
Toxoplasma gondii exonuclease III APE Get druggable targets OG5_126768 All targets in OG5_126768
Trypanosoma cruzi apurinic/apyrimidinic endonuclease, putative Get druggable targets OG5_126768 All targets in OG5_126768
Cryptosporidium parvum conserved hypothetical protein Get druggable targets OG5_126768 All targets in OG5_126768
Schistosoma mansoni Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) Get druggable targets OG5_131088 All targets in OG5_131088
Schistosoma mansoni Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) Get druggable targets OG5_131088 All targets in OG5_131088
Plasmodium yoelii putative AP endonuclease-related Get druggable targets OG5_126768 All targets in OG5_126768
Giardia lamblia Endonuclease/Exonuclease/phosphatase Get druggable targets OG5_126768 All targets in OG5_126768
Schistosoma japonicum ko:K04632 guanine nucleotide binding protein (G protein), alpha stimulating, putative Get druggable targets OG5_131088 All targets in OG5_131088
Schistosoma mansoni ap endonuclease Get druggable targets OG5_126768 All targets in OG5_126768
Echinococcus granulosus DNA apurinic or apyrimidinic site lyase Get druggable targets OG5_126768 All targets in OG5_126768
Schistosoma japonicum DNA-(apurinic or apyrimidinic site) lyase 2, putative Get druggable targets OG5_126768 All targets in OG5_126768
By sequence similarity to non orthologous known druggable targets
Species Potential target Known druggable target Length Alignment span Identity
Schistosoma mansoni GTP-binding protein alpha subunit gna GNAS complex locus 394 aa 450 aa 28.7 %
Obtained from network model

Ranking Plot

Putative Targets List

Species Potential target Raw Global Species
Trichomonas vaginalis conserved hypothetical protein 0.0025 0.0062 0.0158
Brugia malayi Probable G protein-coupled receptor kinase F19C6.1, putative 0.1412 0.821 0.8365
Brugia malayi exodeoxyribonuclease III family protein 0.0023 0.0048 0.0049
Mycobacterium tuberculosis Probable fatty-acid-CoA ligase FadD3 (fatty-acid-CoA synthetase) (fatty-acid-CoA synthase) 0.0035 0.012 0.2633
Entamoeba histolytica exodeoxyribonuclease III, putative 0.0023 0.0048 0.0065
Entamoeba histolytica Rho guanine nucleotide exchange factor, putative 0.0025 0.0062 0.0158
Echinococcus multilocularis tyrosine protein kinase pr2 0.0021 0.0039 0.0024
Brugia malayi Cytochrome P450 family protein 0.0019 0.0029 0.0029
Schistosoma mansoni tyrosine kinase 0.0021 0.0039 0.0024
Echinococcus multilocularis isocitrate dehydrogenase 0.0034 0.0115 0.01
Brugia malayi CHE-14 protein 0.0046 0.0188 0.0191
Brugia malayi PH domain containing protein 0.0025 0.0062 0.0063
Leishmania major apurinic/apyrimidinic endonuclease-redox protein 0.0023 0.0048 0.0681
Echinococcus granulosus protein kinase 0.0021 0.0039 0.0029
Entamoeba histolytica Rho guanine nucleotide exchange factor, putative 0.0025 0.0062 0.0158
Echinococcus multilocularis ephrin type A receptor 4 A 0.0021 0.0039 0.0024
Echinococcus granulosus tyrosine kinase|tyrosine protein kinase Fyn 0.0021 0.0039 0.0029
Schistosoma mansoni protein kinase 0.0021 0.0039 0.0024
Loa Loa (eye worm) cytochrome P450 family protein 0.0049 0.0201 0.0205
Brugia malayi PH domain containing protein 0.0025 0.0062 0.0063
Plasmodium falciparum ataxin-2 like protein, putative 0.0054 0.0233 0.6949
Plasmodium vivax SET domain protein, putative 0.003 0.009 0.1832
Loa Loa (eye worm) syntrophin-1 0.0025 0.0062 0.0063
Loa Loa (eye worm) hypothetical protein 0.0049 0.0205 0.0209
Brugia malayi Probable tyrosine-protein kinase kin-31 0.0021 0.0039 0.0039
Echinococcus multilocularis macrophage colony stimulating factor 1 receptor 0.0021 0.0039 0.0024
Trichomonas vaginalis ankyrin repeat and FYVE domain containing protein, putative 0.0025 0.0062 0.0158
Toxoplasma gondii pyruvate kinase PyKII 0.0035 0.0122 0.2984
Brugia malayi Furin-like cysteine rich region family protein 0.0021 0.0039 0.0039
Brugia malayi Sema domain containing protein 0.0132 0.0688 0.0701
Wolbachia endosymbiont of Brugia malayi exonuclease III 0.0023 0.0048 0.5
Loa Loa (eye worm) hypothetical protein 0.0021 0.0039 0.0039
Giardia lamblia Protein 21.1 0.0021 0.0039 0.00000026162
Entamoeba histolytica PH domain containing protein kinase, putative 0.0032 0.0104 0.0438
Schistosoma mansoni protein kinase 0.0028 0.008 0.0066
Entamoeba histolytica PH domain containing protein kinase, putative 0.0032 0.0104 0.0438
Plasmodium vivax oxysterol-binding protein/PH domain containing protein 0.0025 0.0062 0.0837
Plasmodium falciparum AP endonuclease (DNA-[apurinic or apyrimidinic site] lyase), putative 0.0023 0.0048 0.0346
Toxoplasma gondii exonuclease III APE 0.0023 0.0048 0.0346
Trichomonas vaginalis conserved hypothetical protein 0.0025 0.0062 0.0158
Schistosoma mansoni serine/threonine protein kinase 0.0066 0.03 0.0291
Plasmodium falciparum protein kinase, putative 0.0028 0.008 0.1478
Loa Loa (eye worm) TK/ROR protein kinase 0.0021 0.0039 0.0039
Toxoplasma gondii LsmAD domain-containing protein 0.0054 0.0233 0.6949
Echinococcus multilocularis tyrosine protein kinase Src64B 0.0021 0.0039 0.0024
Loa Loa (eye worm) MH2 domain-containing protein 0.0017 0.0015 0.0015
Echinococcus granulosus tyrosine protein kinase Fyn 0.0021 0.0039 0.0029
Trypanosoma cruzi pyruvate kinase 2, putative 0.0069 0.0319 1
Mycobacterium tuberculosis Probable isocitrate dehydrogenase [NADP] Icd1 (oxalosuccinate decarboxylase) (IDH) (NADP+-specific ICDH) (IDP) 0.0034 0.0115 0.2447
Brugia malayi Pyruvate kinase, muscle isozyme 0.0069 0.0319 0.0325
Echinococcus multilocularis pyruvate kinase 0.0035 0.0122 0.0107
Trichomonas vaginalis conserved hypothetical protein 0.0058 0.0253 0.1451
Trichomonas vaginalis AGC family protein kinase 0.0032 0.0104 0.0438
Loa Loa (eye worm) TK/ABL protein kinase 0.0021 0.0039 0.0039
Echinococcus multilocularis neuropeptide receptor A26 0.0462 0.2628 0.2617
Loa Loa (eye worm) serine/threonine protein kinase 0.0021 0.0039 0.0039
Echinococcus multilocularis tyrosine protein kinase transmembrane receptor 0.0021 0.0039 0.0024
Echinococcus granulosus calcium dependent secretion activator 1 0.0025 0.0062 0.0057
Schistosoma mansoni regulator of G protein signaling 0.0273 0.152 0.1535
Brugia malayi A-kinase anchor protein 10, precursor 0.0273 0.152 0.1548
Trichomonas vaginalis conserved hypothetical protein 0.0025 0.0062 0.0158
Echinococcus granulosus guanine nucleotide binding protein Gs subunit 0.0055 0.0239 0.0274
Brugia malayi serine/threonine-protein kinase 6 0.0066 0.03 0.0306
Brugia malayi hypothetical protein 0.0132 0.0688 0.0701
Loa Loa (eye worm) hypothetical protein 0.0484 0.2759 0.2811
Trichomonas vaginalis AGC family protein kinase 0.0032 0.0104 0.0438
Entamoeba histolytica protein kinase, putative 0.0032 0.0104 0.0438
Echinococcus multilocularis cytohesin 1 0.0025 0.0062 0.0047
Schistosoma mansoni protein kinase 0.0021 0.0039 0.0024
Loa Loa (eye worm) hypothetical protein 0.0025 0.0062 0.0063
Echinococcus granulosus [G-protein-coupledreceptor] kinase 0.1412 0.821 1
Brugia malayi MAX-1A 0.0025 0.0062 0.0063
Schistosoma mansoni hypothetical protein 0.0025 0.0062 0.0048
Echinococcus multilocularis serine:threonine protein kinase 12 B 0.0066 0.03 0.0286
Loa Loa (eye worm) Plekhf2 protein 0.0025 0.0062 0.0063
Schistosoma mansoni tyrosine kinase 0.0021 0.0039 0.0024
Entamoeba histolytica protein kinase, putative 0.0032 0.0104 0.0438
Brugia malayi MH1 domain containing protein 0.0017 0.0015 0.0015
Loa Loa (eye worm) hypothetical protein 0.0069 0.0319 0.0325
Mycobacterium ulcerans hypothetical protein 0.0049 0.0205 0.6064
Loa Loa (eye worm) exodeoxyribonuclease III family protein 0.0023 0.0048 0.0049
Echinococcus granulosus tyrosine protein kinase 0.0021 0.0039 0.0029
Entamoeba histolytica ARF GTPase activating protein, putative 0.0025 0.0062 0.0158
Echinococcus multilocularis regulator of G protein signaling 3 0.0273 0.152 0.1507
Echinococcus granulosus insulin growth factor 1 receptor beta 0.0021 0.0039 0.0029
Brugia malayi Immunoglobulin I-set domain containing protein 0.0021 0.0039 0.0039
Loa Loa (eye worm) hypothetical protein 0.0025 0.0062 0.0063
Echinococcus multilocularis axis inhibition protein axin 0.0273 0.152 0.1507
Schistosoma mansoni patched 1 0.0046 0.0188 0.0176
Schistosoma mansoni serine/threonine protein kinase 0.0021 0.0039 0.0024
Trichomonas vaginalis ankyrin repeat-containing protein, putative 0.0025 0.0062 0.0158
Onchocerca volvulus 0.0049 0.0205 0.0611
Toxoplasma gondii aurora kinase 0.0066 0.03 0.9336
Echinococcus granulosus regulator of G protein signaling 3 0.0273 0.152 0.1836
Leishmania major folate/biopterin transporter, putative 0.0032 0.0104 0.2582
Schistosoma mansoni tyrosine kinase 0.0021 0.0039 0.0024
Echinococcus multilocularis calcium dependent secretion activator 1 0.0025 0.0062 0.0047
Trichomonas vaginalis AGC family protein kinase 0.0066 0.03 0.1767
Schistosoma mansoni tyrosine kinase 0.0021 0.0039 0.0024
Loa Loa (eye worm) sema domain-containing protein 0.0132 0.0688 0.0701
Brugia malayi SH2 domain containing protein 0.0021 0.0039 0.0039
Loa Loa (eye worm) TK/FER protein kinase 0.0021 0.0039 0.0039
Loa Loa (eye worm) plexin A 0.0359 0.2026 0.2064
Echinococcus multilocularis tyrosine protein kinase transmembrane receptor 0.0021 0.0039 0.0024
Trypanosoma brucei rac serine-threonine kinase, putative 0.0032 0.0104 0.2582
Echinococcus granulosus tyrosine kinase 0.0021 0.0039 0.0029
Schistosoma mansoni hypothetical protein 0.0021 0.0039 0.0024
Echinococcus granulosus tyrosine protein kinase Src42A 0.0021 0.0039 0.0029
Trichomonas vaginalis kinesin light chain, putative 0.0025 0.0062 0.0158
Loa Loa (eye worm) AUR protein kinase 0.0066 0.03 0.0306
Echinococcus granulosus retinal guanylyl cyclase 2 0.0021 0.0039 0.0029
Loa Loa (eye worm) sema domain-containing protein 0.0132 0.0688 0.0701
Brugia malayi AMP-binding enzyme family protein 0.0049 0.0205 0.0209
Echinococcus granulosus tyrosine protein kinase pr2 0.0021 0.0039 0.0029
Schistosoma mansoni tyrosine kinase 0.0021 0.0039 0.0024
Schistosoma mansoni regulator of G protein signaling 0.0273 0.152 0.1535
Loa Loa (eye worm) TKL/MLK/HH498 protein kinase 0.0021 0.0039 0.0039
Entamoeba histolytica PH domain containing protein kinase, putative 0.0032 0.0104 0.0438
Loa Loa (eye worm) uncoordinated protein 104 0.0025 0.0062 0.0063
Plasmodium falciparum pyruvate kinase 2 0.0035 0.0122 0.2984
Trichomonas vaginalis voltage and ligand gated potassium channel, putative 0.0034 0.0114 0.0509
Plasmodium falciparum PH domain-containing protein, putative 0.0025 0.0062 0.0837
Echinococcus multilocularis tyrosine protein kinase ABL1 0.0021 0.0039 0.0024
Leishmania major isocitrate dehydrogenase [NADP], mitochondrial precursor, putative 0.0034 0.0115 0.2961
Echinococcus multilocularis tyrosine protein kinase Fgr 0.0021 0.0039 0.0024
Loa Loa (eye worm) RhoGEF domain-containing protein 0.0025 0.0062 0.0063
Loa Loa (eye worm) hypothetical protein 0.0021 0.0039 0.0039
Schistosoma mansoni hypothetical protein 0.0132 0.0688 0.0686
Echinococcus granulosus neuroglian 0.0062 0.0281 0.0324
Entamoeba histolytica protein kinase domain containing protein 0.0066 0.03 0.1767
Schistosoma mansoni tyrosine kinase 0.0021 0.0039 0.0024
Schistosoma mansoni tyrosine kinase 0.0021 0.0039 0.0024
Schistosoma mansoni serine/threonine protein kinase 0.1291 0.7504 0.7642
Plasmodium falciparum phosphatidylinositol transfer protein, putative 0.0025 0.0062 0.0837
Brugia malayi TBC domain containing protein 0.0025 0.0062 0.0063
Toxoplasma gondii isocitrate dehydrogenase 0.0034 0.0115 0.2708
Echinococcus granulosus exocyst complex component 2 0.0058 0.0253 0.0291
Mycobacterium ulcerans acyl-CoA synthetase 0.0049 0.0205 0.6064
Trichomonas vaginalis set domain proteins, putative 0.0236 0.1305 0.8547
Schistosoma mansoni tyrosine kinase 0.0021 0.0039 0.0024
Echinococcus granulosus Regulator of G protein signaling 20 0.0273 0.152 0.1836
Trypanosoma cruzi pyruvate kinase 2, putative 0.0069 0.0319 1
Trypanosoma cruzi PH domain containing protein, putative 0.0025 0.0062 0.1155
Brugia malayi Uncoordinated protein 104 0.0025 0.0062 0.0063
Onchocerca volvulus outspread protein homolog 0.0025 0.0062 0.0086
Onchocerca volvulus Abnormal cell migration protein 10 homolog 0.0025 0.0062 0.0086
Entamoeba histolytica Rho guanine nucleotide exchange factor, putative 0.0025 0.0062 0.0158
Loa Loa (eye worm) MH1 domain-containing protein 0.0017 0.0015 0.0015
Schistosoma mansoni hypothetical protein 0.0025 0.0062 0.0048
Echinococcus multilocularis sterol regulatory element binding protein 0.0046 0.0188 0.0173
Schistosoma mansoni z-protein (S1r protein) 0.0273 0.152 0.1535
Echinococcus granulosus tyrosine protein kinase csk 0.0021 0.0039 0.0029
Trichomonas vaginalis AGC family protein kinase 0.0032 0.0104 0.0438
Trichomonas vaginalis conserved hypothetical protein 0.0025 0.0062 0.0158
Schistosoma mansoni nephrin 0.0062 0.0281 0.0271
Loa Loa (eye worm) TK/DDR protein kinase 0.0021 0.0039 0.0039
Brugia malayi MH2 domain containing protein 0.025 0.1387 0.1413
Trichomonas vaginalis conserved hypothetical protein 0.0273 0.152 1
Echinococcus multilocularis Pleckstrin y 0.0025 0.0062 0.0047
Brugia malayi PH domain containing protein 0.0025 0.0062 0.0063
Echinococcus multilocularis expressed conserved protein 0.0102 0.0512 0.0498
Onchocerca volvulus 0.0025 0.0062 0.0086
Echinococcus granulosus microtubule associated protein 2 0.0689 0.3963 0.4818
Echinococcus granulosus tyrosine protein kinase Fps85D 0.0021 0.0039 0.0029
Loa Loa (eye worm) hypothetical protein 0.0062 0.0281 0.0286
Trypanosoma cruzi protein kinase, putative 0.0021 0.0039 0.0347
Trichomonas vaginalis AGC family protein kinase 0.0032 0.0104 0.0438
Echinococcus multilocularis oxysterol binding protein 3 0.0025 0.0062 0.0047
Echinococcus multilocularis tyrosine protein kinase HCK 0.0021 0.0039 0.0024
Leishmania major protein kinase, putative 0.0032 0.0104 0.2582
Schistosoma mansoni tyrosine kinase 0.0021 0.0039 0.0024
Echinococcus multilocularis arf GAP with SH3 domain, ANK repeat and PH 0.0025 0.0062 0.0047
Trichomonas vaginalis conserved hypothetical protein 0.0273 0.152 1
Schistosoma mansoni tyrosine kinase 0.0021 0.0039 0.0024
Echinococcus multilocularis basic fibroblast growth factor receptor 1 A 0.0021 0.0039 0.0024
Loa Loa (eye worm) hypothetical protein 0.0062 0.0281 0.0286
Trypanosoma brucei Pseudokinase, putative 0.0021 0.0039 0.0347
Loa Loa (eye worm) cytohesin 3 0.0025 0.0062 0.0063
Echinococcus multilocularis regulator of G protein signaling 3 0.0273 0.152 0.1507
Loa Loa (eye worm) AGC/GRK/BARK protein kinase 0.1291 0.7504 0.7645
Schistosoma mansoni Neurotrimin precursor (hNT) 0.0062 0.0281 0.0271
Schistosoma mansoni regulator of G protein signaling 0.0273 0.152 0.1535
Brugia malayi Protein kinase domain containing protein 0.0021 0.0039 0.0039
Loa Loa (eye worm) hypothetical protein 0.0058 0.0253 0.0258
Entamoeba histolytica protein kinase, putative 0.0032 0.0104 0.0438
Entamoeba histolytica protein kinase domain containing protein 0.0028 0.008 0.028
Schistosoma mansoni hypothetical protein 0.017 0.0914 0.0918
Schistosoma mansoni microtubule-associated protein tau 0.0689 0.3963 0.4029
Trichomonas vaginalis ap endonuclease, putative 0.0023 0.0048 0.0065
Loa Loa (eye worm) isocitrate dehydrogenase 0.0034 0.0115 0.0117
Loa Loa (eye worm) hypothetical protein 0.0132 0.0688 0.0701
Echinococcus multilocularis retinal guanylyl cyclase 2 0.0021 0.0039 0.0024
Brugia malayi Adenylate and Guanylate cyclase catalytic domain containing protein 0.0021 0.0039 0.0039
Trypanosoma cruzi PH domain containing protein, putative 0.0025 0.0062 0.1155
Schistosoma mansoni tyrosine kinase 0.0021 0.0039 0.0024
Echinococcus granulosus Ataxin 2 N terminaldomain containing protein 0.0024 0.0058 0.0052
Loa Loa (eye worm) hypothetical protein 0.0132 0.0688 0.0701
Brugia malayi hypothetical protein 0.0054 0.0233 0.0238
Echinococcus multilocularis tyrosine protein kinase Src42A 0.0021 0.0039 0.0024
Schistosoma mansoni hypothetical protein 0.0025 0.0062 0.0048
Trypanosoma brucei PAB1-binding protein , putative 0.0054 0.0233 0.7055
Brugia malayi Protein kinase domain containing protein 0.0021 0.0039 0.0039
Trypanosoma brucei pyruvate kinase 1, putative 0.0069 0.0319 1
Brugia malayi Protein kinase domain containing protein 0.0021 0.0039 0.0039
Brugia malayi Protein kinase domain containing protein 0.0021 0.0039 0.0039
Trichomonas vaginalis AGC family protein kinase 0.0032 0.0104 0.0438
Echinococcus granulosus tyrosine protein kinase transmembrane receptor 0.0021 0.0039 0.0029
Echinococcus granulosus Oxysterol binding protein 11 0.0025 0.0062 0.0057
Entamoeba histolytica hypothetical protein, conserved domain containing 0.0025 0.0062 0.0158
Entamoeba histolytica hypothetical protein 0.0025 0.0062 0.0158
Toxoplasma gondii histone lysine methyltransferase SET/SUV39 0.003 0.009 0.1832
Echinococcus granulosus epidermal growth factor receptor 0.0021 0.0039 0.0029
Loa Loa (eye worm) cytochrome P450 family protein 0.0019 0.0029 0.0029
Entamoeba histolytica protein kinase, putative 0.0032 0.0104 0.0438
Brugia malayi PH domain containing protein 0.0025 0.0062 0.0063
Brugia malayi Syntrophin-1 0.0025 0.0062 0.0063
Trypanosoma brucei NEK family Serine/threonine-protein kinase, putative 0.0032 0.0104 0.2582
Echinococcus granulosus tyrosine protein kinase shark 0.0021 0.0039 0.0029
Plasmodium falciparum pyruvate kinase 0.0069 0.0319 1
Entamoeba histolytica protein kinase, putative 0.0066 0.03 0.1767
Brugia malayi Pre-SET motif family protein 0.003 0.009 0.0092
Loa Loa (eye worm) TK/RYK protein kinase 0.0021 0.0039 0.0039
Brugia malayi hypothetical protein 0.0273 0.152 0.1548
Brugia malayi Variant SH3 domain containing protein 0.0025 0.0062 0.0063
Echinococcus multilocularis Ataxin 2, N terminal,domain containing protein 0.0024 0.0058 0.0043
Trichomonas vaginalis conserved hypothetical protein 0.0273 0.152 1
Loa Loa (eye worm) hypothetical protein 0.0025 0.0062 0.0063
Entamoeba histolytica protein kinase, putative 0.0021 0.0039 0.000000049527
Loa Loa (eye worm) TK protein kinase 0.0021 0.0039 0.0039
Loa Loa (eye worm) hypothetical protein 0.0025 0.0062 0.0063
Schistosoma mansoni hypothetical protein 0.0058 0.0253 0.0243
Echinococcus multilocularis pyruvate kinase 0.0035 0.0122 0.0107
Loa Loa (eye worm) hypothetical protein 0.0273 0.152 0.1548
Entamoeba histolytica protein kinase, putative 0.0032 0.0104 0.0438
Schistosoma mansoni hypothetical protein 0.0132 0.0688 0.0686
Mycobacterium tuberculosis Probable fatty-acid-CoA ligase FadD2 (fatty-acid-CoA synthetase) (fatty-acid-CoA synthase) 0.0049 0.0205 0.5777
Schistosoma mansoni development and differentiation-enhancing factor ddef 0.0025 0.0062 0.0048
Loa Loa (eye worm) Smad1 0.0017 0.0015 0.0015
Echinococcus multilocularis muscleblind protein 1 0.0149 0.0791 0.0777
Brugia malayi hypothetical protein 0.0273 0.152 0.1548
Echinococcus multilocularis activated cdc42 kinase 1 0.0021 0.0039 0.0024
Leishmania major hypothetical protein, conserved 0.0025 0.0062 0.1155
Echinococcus granulosus tyrosine protein kinase transmembrane receptor 0.0021 0.0039 0.0029
Brugia malayi hypothetical protein 0.0025 0.0062 0.0063
Leishmania major hypothetical protein, conserved 0.0025 0.0062 0.1155
Loa Loa (eye worm) hypothetical protein 0.0025 0.0062 0.0063
Schistosoma mansoni regulator of G protein signaling 3 rgs3 0.0273 0.152 0.1535
Schistosoma mansoni centaurin alpha 0.0025 0.0062 0.0048
Echinococcus granulosus fibroblast growth factor receptor 4 0.0021 0.0039 0.0029
Brugia malayi Protein kinase domain containing protein 0.0021 0.0039 0.0039
Entamoeba histolytica hypothetical protein 0.0273 0.152 1
Loa Loa (eye worm) AGC/AKT protein kinase 0.0032 0.0104 0.0105
Mycobacterium tuberculosis Probable fatty-acid-CoA ligase FadD35 (fatty-acid-CoA synthetase) (fatty-acid-CoA synthase) 0.0035 0.012 0.2633
Brugia malayi hypothetical protein 0.0021 0.0039 0.0039
Loa Loa (eye worm) pyruvate kinase 0.0069 0.0319 0.0325
Loa Loa (eye worm) TK protein kinase 0.0021 0.0039 0.0039
Echinococcus multilocularis Ras associated and pleckstrin y 0.0025 0.0062 0.0047
Trichomonas vaginalis AGC family protein kinase 0.0032 0.0104 0.0438
Echinococcus multilocularis tyrosine protein kinase csk 0.0021 0.0039 0.0024
Echinococcus granulosus oxysterol binding protein 1 0.0025 0.0062 0.0057
Entamoeba histolytica p21-activated kinase 0.0032 0.0104 0.0438
Trichomonas vaginalis conserved hypothetical protein 0.0025 0.0062 0.0158
Schistosoma mansoni voltage-gated potassium channel 0.004 0.0148 0.0135
Loa Loa (eye worm) hypothetical protein 0.0037 0.0131 0.0134
Schistosoma mansoni zinc finger protein 0.0025 0.0062 0.0048
Echinococcus granulosus 3'partial|tyrosine protein kinase Fgr 0.0021 0.0039 0.0029
Brugia malayi hypothetical protein 0.0035 0.0121 0.0123
Entamoeba histolytica PH domain containing protein kinase, putative 0.0032 0.0104 0.0438
Onchocerca volvulus Protein melted homolog 0.0025 0.0062 0.0086
Echinococcus multilocularis retinal guanylyl cyclase 2 0.0021 0.0039 0.0024
Echinococcus granulosus collagen type iv alpha 3 binding protein 0.0025 0.0062 0.0057
Entamoeba histolytica PH domain containing protein 0.0025 0.0062 0.0158
Brugia malayi Plexin repeat family protein 0.0302 0.1687 0.1719
Brugia malayi Protein kinase domain containing protein 0.0021 0.0039 0.0039
Toxoplasma gondii calcium dependent protein kinase CDPK7 0.0032 0.0104 0.2315
Brugia malayi Protein kinase domain containing protein 0.0021 0.0039 0.0039
Trichomonas vaginalis AGC family protein kinase 0.0066 0.03 0.1767
Echinococcus multilocularis beta 1 syntrophin 0.0025 0.0062 0.0047
Loa Loa (eye worm) CYP4Cod1 0.0019 0.0029 0.0029
Trichomonas vaginalis Clan MA, family M8, leishmanolysin-like metallopeptidase 0.0058 0.0253 0.1451
Loa Loa (eye worm) hypothetical protein 0.0025 0.0062 0.0063
Trypanosoma cruzi apurinic/apyrimidinic endonuclease, putative 0.0023 0.0048 0.0681
Trichomonas vaginalis Clan MA, family M8, leishmanolysin-like metallopeptidase 0.0058 0.0253 0.1451
Loa Loa (eye worm) hypothetical protein 0.0021 0.0039 0.0039
Echinococcus multilocularis guanine nucleotide binding protein G(s) subunit 0.0055 0.0239 0.0225
Schistosoma mansoni axis inhibition protein axin 0.0273 0.152 0.1535
Brugia malayi Protein kinase domain containing protein 0.0021 0.0039 0.0039
Trypanosoma cruzi rac serine-threonine kinase, putative 0.0032 0.0104 0.2582
Leishmania major 4-coumarate:coa ligase-like protein 0.0049 0.0205 0.6064
Loa Loa (eye worm) TK/FER protein kinase 0.0021 0.0039 0.0039
Schistosoma mansoni histone-lysine n-methyltransferase setb1 0.003 0.009 0.0076
Loa Loa (eye worm) hypothetical protein 0.0149 0.0791 0.0806
Loa Loa (eye worm) TK protein kinase 0.0021 0.0039 0.0039
Schistosoma mansoni tyrosine kinase 0.0021 0.0039 0.0024
Trichomonas vaginalis guanyl-nucleotide exchange factor, putative 0.0025 0.0062 0.0158
Loa Loa (eye worm) hypothetical protein 0.0025 0.0062 0.0063
Schistosoma mansoni rhogef and pleckstrin domain protein 0.0025 0.0062 0.0048
Echinococcus multilocularis epidermal growth factor receptor 0.0021 0.0039 0.0024
Brugia malayi Protein kinase domain containing protein 0.0021 0.0039 0.0039
Echinococcus multilocularis type II inositol 3,4 bisphosphate 4 phosphatase 0.0025 0.0062 0.0047
Loa Loa (eye worm) hypothetical protein 0.0062 0.0281 0.0286
Trichomonas vaginalis AGC family protein kinase 0.0032 0.0104 0.0438
Entamoeba histolytica pyruvate kinase, putative 0.0048 0.0197 0.1067
Trypanosoma brucei apurinic/apyrimidinic endonuclease, putative 0.0023 0.0048 0.0681
Schistosoma mansoni protein kinase 0.0021 0.0039 0.0024
Brugia malayi probable spectrin beta chain 0.0025 0.0062 0.0063
Brugia malayi serine/threonine kinase 12 0.0066 0.03 0.0306
Echinococcus multilocularis pyruvate kinase 0.0069 0.0319 0.0304
Echinococcus granulosus sterol regulatory element binding protein 0.0046 0.0188 0.0211
Echinococcus granulosus type II inositol 34 bisphosphate 4 phosphatase 0.0025 0.0062 0.0057
Toxoplasma gondii AtPH1 family protein 0.0025 0.0062 0.0837
Mycobacterium tuberculosis Probable fatty-acid-CoA ligase FadD7 (fatty-acid-CoA synthetase) (fatty-acid-CoA synthase) 0.0035 0.012 0.2633
Echinococcus multilocularis tyrosine protein kinase Srms 0.0021 0.0039 0.0024
Loa Loa (eye worm) hypothetical protein 0.0025 0.0062 0.0063
Schistosoma mansoni vav2 0.0025 0.0062 0.0048
Echinococcus granulosus axis inhibition protein axin 0.0273 0.152 0.1836
Trypanosoma brucei Serine/threonine-protein kinase NEK21, putative 0.0032 0.0104 0.2582
Echinococcus multilocularis Arf GAP and Pleckstrin domain containing protein 0.0025 0.0062 0.0047
Echinococcus granulosus expressed conserved protein 0.0102 0.0512 0.0607
Brugia malayi Oxysterol binding protein 0.0025 0.0062 0.0063
Trichomonas vaginalis voltage and ligand gated potassium channel, putative 0.0034 0.0114 0.0509
Trichomonas vaginalis TKL family protein kinase 0.0021 0.0039 0.000000049527
Trichomonas vaginalis conserved hypothetical protein 0.0046 0.0188 0.1007
Echinococcus granulosus neuropeptide receptor A26 0.0462 0.2628 0.3188
Schistosoma mansoni defective proboscis extension response (dpr)-related 0.0062 0.0281 0.0271
Echinococcus granulosus natriuretic peptide receptor 1 0.0021 0.0039 0.0029
Echinococcus granulosus beta-adrenergic receptor kinase 0.1291 0.7504 0.9138
Schistosoma mansoni Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) 0.0055 0.0239 0.0229
Entamoeba histolytica hypothetical protein, conserved domain containing 0.0025 0.0062 0.0158
Onchocerca volvulus 0.0025 0.0062 0.0086
Schistosoma mansoni tyrosine kinase 0.0021 0.0039 0.0024
Schistosoma mansoni hypothetical protein 0.0364 0.2057 0.2083
Echinococcus multilocularis axis inhibition protein axin 0.0273 0.152 0.1507
Brugia malayi Regulator of G protein signaling domain containing protein 0.0273 0.152 0.1548
Schistosoma mansoni syntrophin 0.0025 0.0062 0.0048
Brugia malayi Cytochrome P450 family protein 0.0019 0.0029 0.0029
Echinococcus multilocularis integrin linked protein kinase 0.0021 0.0039 0.0024
Loa Loa (eye worm) hypothetical protein 0.0021 0.0039 0.0039
Brugia malayi Tyrosine-protein kinase F09A5.2 in chromosome X, putative 0.0021 0.0039 0.0039
Trichomonas vaginalis conserved hypothetical protein 0.0025 0.0062 0.0158
Trichomonas vaginalis AGC family protein kinase 0.0032 0.0104 0.0438
Echinococcus multilocularis tyrosine protein kinase 0.0021 0.0039 0.0024
Trypanosoma cruzi PAB1-binding protein , putative 0.0054 0.0233 0.7055
Brugia malayi PH domain containing protein 0.0025 0.0062 0.0063
Entamoeba histolytica PH domain containing protein 0.0025 0.0062 0.0158
Echinococcus granulosus pyruvate kinase 0.0035 0.0122 0.0131
Brugia malayi Protein kinase domain containing protein 0.0021 0.0039 0.0039
Echinococcus granulosus pyruvate kinase 0.0035 0.0122 0.0131
Echinococcus granulosus DNA apurinic or apyrimidinic site lyase 0.0023 0.0048 0.004
Loa Loa (eye worm) hypothetical protein 0.0025 0.0062 0.0063
Loa Loa (eye worm) hypothetical protein 0.0149 0.0791 0.0806
Brugia malayi Cytochrome P450 family protein 0.0049 0.0201 0.0205
Trichomonas vaginalis AGC family protein kinase 0.0032 0.0104 0.0438
Echinococcus granulosus tyrosine protein kinase Fyn 0.0021 0.0039 0.0029
Echinococcus granulosus guanine nucleotide binding protein Gs subunit 0.0055 0.0239 0.0274
Trypanosoma brucei PH domain containing protein, putative 0.0025 0.0062 0.1155
Echinococcus granulosus tyrosine protein kinase Lyn 0.0028 0.008 0.0079
Mycobacterium ulcerans long-chain fatty-acid CoA ligase 0.0049 0.0205 0.6064
Trichomonas vaginalis centaurin beta, putative 0.0025 0.0062 0.0158
Trichomonas vaginalis AGC family protein kinase 0.0032 0.0104 0.0438
Echinococcus multilocularis tyrosine protein kinase Fyn 0.0021 0.0039 0.0024
Loa Loa (eye worm) RGC/RGC protein kinase 0.0021 0.0039 0.0039
Brugia malayi Protein kinase domain containing protein 0.0021 0.0039 0.0039
Echinococcus granulosus transcription factor collier 0.0058 0.0253 0.0291
Schistosoma mansoni pyruvate kinase 0.0035 0.0122 0.0109
Plasmodium vivax ataxin-2 like protein, putative 0.0054 0.0233 0.6949
Loa Loa (eye worm) RGC/RGC protein kinase 0.0021 0.0039 0.0039
Echinococcus granulosus cytohesin 1 0.0025 0.0062 0.0057
Trypanosoma cruzi serine/threonine protein kinase, putative 0.0032 0.0104 0.2582
Trypanosoma brucei isocitrate dehydrogenase, putative 0.0034 0.0115 0.2961
Echinococcus granulosus myotubularin protein 13 0.0025 0.0062 0.0057
Echinococcus granulosus DCC interacting protein 13 beta 0.0025 0.0062 0.0057
Loa Loa (eye worm) hypothetical protein 0.0025 0.0062 0.0063
Echinococcus multilocularis mitogen activated protein kinase kinase kinase 0.0021 0.0039 0.0024
Loa Loa (eye worm) variant SH3 domain-containing protein 0.0025 0.0062 0.0063
Schistosoma mansoni hypothetical protein 0.0024 0.0058 0.0044
Echinococcus multilocularis tyrosine protein kinase lyn tyrosine protein kinase blk 0.0021 0.0039 0.0024
Toxoplasma gondii hypothetical protein 0.0025 0.0062 0.0837
Echinococcus multilocularis oxysterol binding protein 9 0.0025 0.0062 0.0047
Echinococcus multilocularis mitogen activated protein kinase kinase kinase 0.0021 0.0039 0.0024
Echinococcus multilocularis protein patched 0.0046 0.0188 0.0173
Loa Loa (eye worm) hypothetical protein 0.0058 0.0253 0.0258
Echinococcus granulosus arf GAP with SH3 domain ANK repeat and PH 0.0025 0.0062 0.0057
Echinococcus granulosus twitchin 0.0069 0.0322 0.0375
Trichomonas vaginalis TKL family protein kinase 0.0021 0.0039 0.000000049527
Entamoeba histolytica protein kinase , putative 0.0066 0.03 0.1767
Brugia malayi Receptor family ligand binding region containing protein 0.0021 0.0039 0.0039
Trichomonas vaginalis centaurin alpha, putative 0.0025 0.0062 0.0158
Echinococcus granulosus Pleckstrin y 0.0025 0.0062 0.0057
Mycobacterium ulcerans long-chain-fatty-acid-CoA ligase 0.0049 0.0205 0.6064
Entamoeba histolytica hypothetical protein 0.0025 0.0062 0.0158
Trypanosoma brucei aurora B kinase 0.0066 0.03 0.9359
Echinococcus multilocularis Pleckstrin y 0.0025 0.0062 0.0047
Schistosoma mansoni hypothetical protein 0.0045 0.0178 0.0166
Echinococcus granulosus aurora kinase A 0.0066 0.03 0.0348
Loa Loa (eye worm) pyruvate kinase 0.0069 0.0319 0.0325
Onchocerca volvulus 0.0025 0.0062 0.0086
Echinococcus granulosus tyrosine protein kinase Fes:Fps 0.0021 0.0039 0.0029
Echinococcus granulosus dynamin 1 0.0025 0.0062 0.0057
Brugia malayi PH domain containing protein 0.0025 0.0062 0.0063
Treponema pallidum exodeoxyribonuclease (exoA) 0.0023 0.0048 0.5
Echinococcus granulosus raf serine:threonine protein kinase 0.0021 0.0039 0.0029
Schistosoma mansoni hypothetical protein 0.0045 0.0178 0.0166
Loa Loa (eye worm) hypothetical protein 0.0049 0.0205 0.0209
Onchocerca volvulus 0.0132 0.0688 0.2386
Brugia malayi Tyrosine-protein kinase PR2 0.0021 0.0039 0.0039
Loa Loa (eye worm) AGC/GRK/GRK protein kinase 0.1412 0.821 0.8365
Loa Loa (eye worm) hypothetical protein 0.0062 0.0281 0.0286
Entamoeba histolytica hypothetical protein, conserved domain containing 0.0025 0.0062 0.0158
Brugia malayi AMP-binding enzyme family protein 0.0049 0.0205 0.0209
Brugia malayi hypothetical protein 0.0132 0.0688 0.0701
Brugia malayi Protein kinase domain containing protein 0.0021 0.0039 0.0039
Trichomonas vaginalis conserved hypothetical protein 0.0025 0.0062 0.0158
Brugia malayi Immunoglobulin I-set domain containing protein 0.0083 0.0405 0.0412
Echinococcus granulosus A kinase anchor protein 10 mitochondrial 0.0273 0.152 0.1836
Echinococcus multilocularis NADP dependent isocitrate dehydrogenase 0.0034 0.0115 0.01
Loa Loa (eye worm) G protein-coupled receptor kinase 1 0.1412 0.821 0.8365
Trypanosoma brucei serine/threonine-protein kinase NRKB, putative 0.0032 0.0104 0.2582
Echinococcus granulosus Protein patched homolog 1 0.0046 0.0188 0.0211
Entamoeba histolytica Rho guanine nucleotide exchange factor, putative 0.0025 0.0062 0.0158
Trichomonas vaginalis conserved hypothetical protein 0.0025 0.0062 0.0158
Leishmania major pyruvate kinase 0.0069 0.0319 1
Onchocerca volvulus 0.0025 0.0062 0.0086
Schistosoma mansoni hypothetical protein 0.0045 0.0178 0.0166
Trypanosoma cruzi Serine/threonine-protein kinase NEK21, putative 0.0032 0.0104 0.2582
Echinococcus multilocularis collagen type iv alpha 3 binding protein 0.0025 0.0062 0.0047
Entamoeba histolytica hypothetical protein 0.0058 0.0253 0.1451
Schistosoma mansoni tyrosine kinase 0.0021 0.0039 0.0024
Trichomonas vaginalis TKL family protein kinase 0.0021 0.0039 0.000000049527
Loa Loa (eye worm) hypothetical protein 0.0025 0.0062 0.0063
Trichomonas vaginalis AGC family protein kinase 0.0032 0.0104 0.0438
Echinococcus granulosus NADP dependent isocitrate dehydrogenase 0.0034 0.0115 0.0121
Schistosoma mansoni regulator of G protein signaling 17 19 20 (rgs17 19 20) 0.0273 0.152 0.1535
Trichomonas vaginalis conserved hypothetical protein 0.0058 0.0253 0.1451
Brugia malayi isocitrate dehydrogenase 0.0034 0.0115 0.0117
Brugia malayi IPT/TIG domain containing protein 0.0058 0.0253 0.0258
Brugia malayi Tyrosine-protein kinase abl-1 0.0021 0.0039 0.0039
Loa Loa (eye worm) TK/ALK protein kinase 0.0021 0.0039 0.0039
Entamoeba histolytica hypothetical protein, conserved domain containing 0.0025 0.0062 0.0158
Loa Loa (eye worm) TK/FER protein kinase 0.0021 0.0039 0.0039
Brugia malayi Muscleblind-like protein 0.0149 0.0791 0.0806
Leishmania major hypothetical protein, conserved 0.0054 0.0233 0.7055
Loa Loa (eye worm) TK/FER protein kinase 0.0021 0.0039 0.0039
Trichomonas vaginalis AGC family protein kinase 0.0032 0.0104 0.0438
Brugia malayi Fibronectin type III domain containing protein 0.0062 0.0281 0.0286
Echinococcus granulosus mitogen-activated protein kinase kinase kinase 9 0.0021 0.0039 0.0029
Echinococcus granulosus muscleblind protein 0.0149 0.0791 0.0947
Schistosoma mansoni protein kinase 0.0021 0.0039 0.0024
Schistosoma mansoni tyrosine kinase 0.0021 0.0039 0.0024
Onchocerca volvulus 0.0484 0.2759 1
Echinococcus granulosus mitogen activated protein kinase kinase kinase 0.0021 0.0039 0.0029
Plasmodium falciparum ataxin-2 like protein, putative 0.0054 0.0233 0.6949
Onchocerca volvulus Pyruvate kinase homolog 0.0069 0.0319 0.1031
Giardia lamblia Endonuclease/Exonuclease/phosphatase 0.0023 0.0048 0.0346
Echinococcus granulosus potassium voltage gated channel subfamily H 0.0036 0.0128 0.0138
Echinococcus granulosus tyrosine protein kinase Fyn 0.0021 0.0039 0.0029
Schistosoma mansoni oxysterol-binding protein 1 0.0025 0.0062 0.0048
Echinococcus multilocularis tyrosine protein kinase shark 0.0021 0.0039 0.0024
Echinococcus multilocularis raf serine:threonine protein kinase 0.0021 0.0039 0.0024
Trypanosoma brucei Flagellum attachment zone protein 20 0.0021 0.0039 0.0347
Schistosoma mansoni Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) 0.0055 0.0239 0.0229
Schistosoma mansoni protein kinase 0.0028 0.008 0.0066
Loa Loa (eye worm) hypothetical protein 0.0025 0.0062 0.0063
Echinococcus multilocularis myotubularin protein 13 0.0025 0.0062 0.0047
Trichomonas vaginalis Clan MA, family M8, leishmanolysin-like metallopeptidase 0.0058 0.0253 0.1451
Trichomonas vaginalis conserved hypothetical protein 0.0025 0.0062 0.0158
Trypanosoma cruzi STE/STE11 serine/threonine-protein kinase, putative 0.0028 0.008 0.1774
Schistosoma mansoni protein kinase 0.0021 0.0039 0.0024
Leishmania major pyruvate kinase 0.0069 0.0319 1
Loa Loa (eye worm) hypothetical protein 0.0037 0.0131 0.0134
Schistosoma mansoni tyrosine kinase 0.0021 0.0039 0.0024
Echinococcus multilocularis protein KINase family member (kin 25) 0.0021 0.0039 0.0024
Echinococcus granulosus ras specific guanine nucleotide releasing factor 0.0025 0.0062 0.0057
Echinococcus multilocularis tyrosine protein kinase csk 0.0021 0.0039 0.0024
Trypanosoma cruzi hypothetical protein 0.0025 0.0062 0.1155
Schistosoma mansoni serine/threonine protein kinase 0.1685 0.9815 1
Leishmania major 4-coumarate:coa ligase-like protein 0.0049 0.0205 0.6064
Schistosoma mansoni hypothetical protein 0.0058 0.0253 0.0243
Plasmodium vivax hypothetical protein, conserved 0.0025 0.0062 0.0837
Echinococcus multilocularis pyruvate kinase 0.0069 0.0319 0.0304
Loa Loa (eye worm) hypothetical protein 0.0025 0.0062 0.0063
Entamoeba histolytica hypothetical protein 0.0032 0.0104 0.0438
Echinococcus granulosus atrial natriuretic peptide receptor 1 0.0021 0.0039 0.0029
Schistosoma mansoni tyrosine-protein kinase fps85d 0.0021 0.0039 0.0024
Trypanosoma cruzi STE/STE11 serine/threonine-protein kinase, putative 0.0028 0.008 0.1774
Echinococcus multilocularis tyrosine protein kinase Fyn 0.0021 0.0039 0.0024
Loa Loa (eye worm) hypothetical protein 0.0037 0.0131 0.0134
Brugia malayi ephrin receptor 1 precursor 0.0021 0.0039 0.0039
Schistosoma mansoni zinc finger protein 0.0025 0.0062 0.0048
Brugia malayi hypothetical protein 0.0484 0.2759 0.2811
Loa Loa (eye worm) hypothetical protein 0.0025 0.0062 0.0063
Loa Loa (eye worm) TK protein kinase 0.0021 0.0039 0.0039
Brugia malayi Protein kinase domain containing protein 0.0021 0.0039 0.0039
Trichomonas vaginalis conserved hypothetical protein 0.0025 0.0062 0.0158
Loa Loa (eye worm) hypothetical protein 0.0132 0.0688 0.0701
Echinococcus granulosus serine:threonine protein kinase 12 B 0.0066 0.03 0.0348
Brugia malayi PXA domain containing protein 0.0273 0.152 0.1548
Brugia malayi SH2 domain containing protein 0.0021 0.0039 0.0039
Loa Loa (eye worm) pre-SET domain-containing protein family protein 0.0208 0.1136 0.1157
Echinococcus multilocularis oxysterol binding protein 1 0.0025 0.0062 0.0047
Entamoeba histolytica Rho guanine nucleotide exchange factor, putative 0.0025 0.0062 0.0158
Schistosoma mansoni histone-lysine n-methyltransferase setb1 0.003 0.009 0.0076
Loa Loa (eye worm) hypothetical protein 0.0132 0.0688 0.0701
Brugia malayi Protein kinase domain containing protein 0.0021 0.0039 0.0039
Toxoplasma gondii Oxysterol-binding protein 0.0025 0.0062 0.0837
Echinococcus granulosus neurotracting:lsamp:neurotrimin:obcam 0.0062 0.0281 0.0324
Loa Loa (eye worm) hypothetical protein 0.0021 0.0039 0.0039
Echinococcus multilocularis epidermal growth factor receptor 0.0021 0.0039 0.0024
Trypanosoma cruzi NEK family Serine/threonine-protein kinase, putative 0.0025 0.0062 0.1155
Echinococcus multilocularis tyrosine protein kinase Abl 0.0021 0.0039 0.0024
Trypanosoma cruzi isocitrate dehydrogenase [NADP], mitochondrial precursor, putative 0.0034 0.0115 0.2961
Loa Loa (eye worm) hypothetical protein 0.0025 0.0062 0.0063
Loa Loa (eye worm) TK protein kinase 0.0021 0.0039 0.0039
Loa Loa (eye worm) RGC/RGC protein kinase 0.0021 0.0039 0.0039
Echinococcus multilocularis tyrosine protein kinase lyn lyn a protein tyrosine kinase lymphocyte specific protein tyrosine kinase 0.0021 0.0039 0.0024
Trichomonas vaginalis AGC family protein kinase 0.0032 0.0104 0.0438
Trypanosoma cruzi hypothetical protein 0.0025 0.0062 0.1155
Echinococcus granulosus proto oncogene tyrosine protein kinase LCK 0.0021 0.0039 0.0029
Echinococcus granulosus GRB2 associated binding protein 3 0.0025 0.0062 0.0057
Echinococcus granulosus tyrosine protein kinase HCK 0.0021 0.0039 0.0029
Loa Loa (eye worm) hypothetical protein 0.0062 0.0281 0.0286
Trichomonas vaginalis conserved hypothetical protein 0.0025 0.0062 0.0158
Brugia malayi GTP-binding regulatory protein Gs alpha-S chain, putative 0.0055 0.0239 0.0244
Schistosoma mansoni phosphoinositol 4-phosphate adaptor protein 0.0025 0.0062 0.0048
Trypanosoma cruzi NIMA-related kinase, putative 0.0032 0.0104 0.2582
Brugia malayi Pre-SET motif family protein 0.0208 0.1136 0.1157
Brugia malayi PH domain containing protein 0.0025 0.0062 0.0063
Mycobacterium tuberculosis Fatty-acid-AMP ligase FadD30 (fatty-acid-AMP synthetase) (fatty-acid-AMP synthase) 0.0037 0.0131 0.307
Loa Loa (eye worm) TKL/RAF/RAF protein kinase 0.0021 0.0039 0.0039
Loa Loa (eye worm) hypothetical protein 0.0021 0.0039 0.0039
Trichomonas vaginalis Clan MA, family M8, leishmanolysin-like metallopeptidase 0.0058 0.0253 0.1451
Brugia malayi Cadps2 protein 0.0025 0.0062 0.0063
Plasmodium falciparum oxysterol-binding protein, putative 0.0025 0.0062 0.0837
Schistosoma mansoni tyrosine kinase 0.0021 0.0039 0.0024
Loa Loa (eye worm) TK/FER protein kinase 0.0021 0.0039 0.0039
Brugia malayi PH domain containing protein 0.0025 0.0062 0.0063
Echinococcus multilocularis transfer RNA-Thr 0.0021 0.0039 0.0024
Entamoeba histolytica serine/threonine- protein kinase 6 , putative 0.0066 0.03 0.1767
Echinococcus granulosus c src tyrosine kinase 0.0021 0.0039 0.0029
Giardia lamblia Aurora kinase 0.0066 0.03 0.9336
Entamoeba histolytica PH domain containing protein kinase, putative 0.0032 0.0104 0.0438
Trypanosoma brucei protein kinase, putative 0.0032 0.0104 0.2582
Trichomonas vaginalis conserved hypothetical protein 0.0273 0.152 1
Plasmodium falciparum serine/threonine protein kinase, putative 0.0066 0.03 0.9336
Echinococcus multilocularis NADP dependent isocitrate dehydrogenase 0.0034 0.0115 0.01
Echinococcus multilocularis Niemann Pick C1 protein 0.0155 0.0824 0.081
Loa Loa (eye worm) hypothetical protein 0.0046 0.0188 0.0191
Entamoeba histolytica Niemann-Pick C1 protein, putative 0.0108 0.0551 0.3459
Brugia malayi PXA domain containing protein 0.0273 0.152 0.1548
Echinococcus multilocularis beta adrenergic receptor kinase 0.1291 0.7504 0.75
Schistosoma mansoni ap endonuclease 0.0023 0.0048 0.0034
Loa Loa (eye worm) hypothetical protein 0.0273 0.152 0.1548
Loa Loa (eye worm) TK/FER protein kinase 0.0021 0.0039 0.0039
Plasmodium falciparum calcium-dependent protein kinase 7 0.0032 0.0104 0.2315
Echinococcus multilocularis tyrosine protein kinase Fes:Fps 0.0021 0.0039 0.0024
Onchocerca volvulus Pyruvate kinase homolog 0.0069 0.0319 0.1031
Echinococcus multilocularis proto oncogene tyrosine protein kinase LCK 0.0021 0.0039 0.0024
Loa Loa (eye worm) TK protein kinase 0.0021 0.0039 0.0039
Loa Loa (eye worm) TK/FER protein kinase 0.0021 0.0039 0.0039
Trypanosoma cruzi apurinic/apyrimidinic endonuclease 0.0023 0.0048 0.0681
Brugia malayi Protein kinase domain containing protein 0.0021 0.0039 0.0039
Schistosoma mansoni semaphorin 5-related 0.0132 0.0688 0.0686
Echinococcus multilocularis protein kinase 0.0021 0.0039 0.0024
Loa Loa (eye worm) hypothetical protein 0.0273 0.152 0.1548
Schistosoma mansoni tyrosine kinase 0.0021 0.0039 0.0024
Onchocerca volvulus 0.0025 0.0062 0.0086
Toxoplasma gondii hypothetical protein 0.0025 0.0062 0.0837
Brugia malayi Protein kinase domain containing protein 0.0032 0.0104 0.0105
Echinococcus granulosus retinal guanylyl cyclase 2 0.0021 0.0039 0.0029
Loa Loa (eye worm) AUR protein kinase 0.0066 0.03 0.0306
Echinococcus granulosus receptor type guanylyl cyclase 0.0021 0.0039 0.0029
Brugia malayi Adenylate and Guanylate cyclase catalytic domain containing protein 0.0021 0.0039 0.0039
Echinococcus multilocularis NADP dependent isocitrate dehydrogenase 0.0034 0.0115 0.01
Echinococcus granulosus Pleckstrin domain containing protein family B 0.0025 0.0062 0.0057
Echinococcus multilocularis Pleckstrin y 0.0025 0.0062 0.0047
Trichomonas vaginalis conserved hypothetical protein 0.0025 0.0062 0.0158
Trypanosoma cruzi NEK family Serine/threonine-protein kinase, putative 0.0032 0.0104 0.2582
Leishmania major serine/threonine-protein kinase a, putative 0.0032 0.0104 0.2582
Entamoeba histolytica acyl-CoA synthetase, putative 0.0049 0.0205 0.1121
Loa Loa (eye worm) oxysterol binding protein 0.0025 0.0062 0.0063
Brugia malayi Smad1 0.0017 0.0015 0.0015
Schistosoma mansoni tyrosine kinase 0.0021 0.0039 0.0024
Trypanosoma cruzi Serine/threonine-protein kinase NEK21, putative 0.0032 0.0104 0.2582
Toxoplasma gondii isocitrate dehydrogenase 0.0034 0.0115 0.2708
Echinococcus multilocularis GRB2 associated binding protein 3 0.0025 0.0062 0.0047
Loa Loa (eye worm) pyruvate kinase-PB 0.0048 0.0197 0.02
Loa Loa (eye worm) TK/FER protein kinase 0.0021 0.0039 0.0039
Echinococcus granulosus Niemann Pick C1 protein 0.0108 0.0551 0.0654
Trichomonas vaginalis conserved hypothetical protein 0.0058 0.0253 0.1451
Loa Loa (eye worm) hypothetical protein 0.0048 0.0197 0.02
Schistosoma mansoni serine/threonine RGC 0.0021 0.0039 0.0024
Loa Loa (eye worm) TK/FER protein kinase 0.0021 0.0039 0.0039
Echinococcus multilocularis neuropeptide s receptor 0.0462 0.2628 0.2617
Trichomonas vaginalis AGC family protein kinase 0.0032 0.0104 0.0438
Brugia malayi Protein kinase domain containing protein 0.0021 0.0039 0.0039
Echinococcus multilocularis G protein coupled receptor kinase 1 0.1018 0.5899 0.5893
Schistosoma mansoni cell adhesion molecule 0.0062 0.0281 0.0271
Echinococcus granulosus semaphorin 5B 0.0132 0.0688 0.0821
Trypanosoma brucei pyruvate kinase 1 0.0069 0.0319 1
Brugia malayi Protein kinase domain containing protein 0.0021 0.0039 0.0039
Brugia malayi PH domain containing protein 0.0025 0.0062 0.0063
Schistosoma mansoni Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) 0.0055 0.0239 0.0229
Schistosoma mansoni growth factor receptor-bound protein 0.0025 0.0062 0.0048
Onchocerca volvulus 0.0302 0.1687 0.6061
Schistosoma mansoni histone-lysine n-methyltransferase suv9 0.003 0.009 0.0076
Trichomonas vaginalis AGC family protein kinase 0.0032 0.0104 0.0438
Brugia malayi Protein kinase domain containing protein 0.0021 0.0039 0.0039
Trichomonas vaginalis Clan MA, family M8, leishmanolysin-like metallopeptidase 0.0058 0.0253 0.1451
Echinococcus multilocularis activin receptor type 0.0028 0.008 0.0065
Trichomonas vaginalis AGC family protein kinase 0.0032 0.0104 0.0438
Schistosoma mansoni serine/threonine protein kinase 0.0021 0.0039 0.0024
Brugia malayi protein-tyrosine kinase 0.0021 0.0039 0.0039
Echinococcus granulosus pyruvate kinase 0.0069 0.0319 0.0371
Echinococcus granulosus activated cdc42 kinase 1 0.0021 0.0039 0.0029
Schistosoma mansoni tyrosine kinase 0.0021 0.0039 0.0024
Loa Loa (eye worm) TK/Met protein kinase 0.0021 0.0039 0.0039
Echinococcus granulosus epidermal growth factor receptor 0.0021 0.0039 0.0029
Trypanosoma cruzi serine/threonine-protein kinase NRKB, putative 0.0032 0.0104 0.2582
Loa Loa (eye worm) SRC-1 0.0021 0.0039 0.0039
Brugia malayi DNA-binding protein LAG-1 0.0058 0.0253 0.0258
Loa Loa (eye worm) TK protein kinase 0.0021 0.0039 0.0039
Echinococcus multilocularis rac serine:threonine kinase 0.0032 0.0104 0.0089
Echinococcus multilocularis Pleckstrin domain containing protein, family B 0.0025 0.0062 0.0047
Schistosoma mansoni hypothetical protein 0.0364 0.2057 0.2083
Brugia malayi Raf kinase 0.0021 0.0039 0.0039
Trichomonas vaginalis AGC family protein kinase 0.0032 0.0104 0.0438
Brugia malayi Protein kinase domain containing protein 0.0021 0.0039 0.0039
Trypanosoma cruzi NIMA-related kinase, putative 0.0032 0.0104 0.2582
Entamoeba histolytica Rho guanine nucleotide exchange factor, putative 0.0025 0.0062 0.0158
Echinococcus multilocularis tyrosine protein kinase Btk29A 0.0021 0.0039 0.0024
Echinococcus multilocularis A kinase anchor protein 10, mitochondrial 0.0273 0.152 0.1507
Brugia malayi Protein kinase domain containing protein 0.0021 0.0039 0.0039
Echinococcus granulosus plexin a4 0.0359 0.2026 0.2454
Schistosoma mansoni tyrosine kinase 0.0021 0.0039 0.0024
Trichomonas vaginalis conserved hypothetical protein 0.0273 0.152 1
Echinococcus multilocularis pdz domain containing protein 0.0025 0.0062 0.0047
Trichomonas vaginalis conserved hypothetical protein 0.0058 0.0253 0.1451
Entamoeba histolytica hypothetical protein 0.0025 0.0062 0.0158
Echinococcus granulosus 5'partial|histone lysine N methyltransferase SETDB2 0.0029 0.0084 0.0083
Echinococcus granulosus tyrosine protein kinase csk 0.0021 0.0039 0.0029
Trichomonas vaginalis AGC family protein kinase 0.0032 0.0104 0.0438
Entamoeba histolytica hypothetical protein 0.0025 0.0062 0.0158
Onchocerca volvulus 0.0025 0.0062 0.0086
Schistosoma mansoni tyrosine-protein kinase fps85d 0.0021 0.0039 0.0024
Plasmodium falciparum conserved Plasmodium protein, unknown function 0.0025 0.0062 0.0837
Schistosoma mansoni axis inhibition protein axin 0.0273 0.152 0.1535
Schistosoma mansoni myotubularin-related protein 0.0025 0.0062 0.0048
Echinococcus granulosus axis inhibition protein axin 0.0273 0.152 0.1836
Brugia malayi Dynamin 0.0025 0.0062 0.0063
Brugia malayi Niemann-Pick C1 protein precursor 0.0108 0.0551 0.0561
Trypanosoma cruzi PAB1-binding protein , putative 0.0054 0.0233 0.7055
Loa Loa (eye worm) TK/FER protein kinase 0.0021 0.0039 0.0039
Echinococcus multilocularis FL cytokine receptor 0.0021 0.0039 0.0024
Trichomonas vaginalis ankyrin repeat-containing protein, putative 0.0021 0.0039 0.000000049527
Trypanosoma brucei AGC/RSK family serine/threonine kinase, putative 0.0021 0.0039 0.0347
Entamoeba histolytica hypothetical protein 0.0025 0.0062 0.0158
Mycobacterium tuberculosis Probable pyruvate kinase PykA 0.0069 0.0319 1
Loa Loa (eye worm) TK/ACK protein kinase 0.0021 0.0039 0.0039
Echinococcus granulosus Pleckstrin y 0.0025 0.0062 0.0057
Brugia malayi MH2 domain containing protein 0.0017 0.0015 0.0015
Echinococcus multilocularis neuroglian 0.0062 0.0281 0.0266
Entamoeba histolytica hypothetical protein 0.0058 0.0253 0.1451
Echinococcus granulosus neuropeptide s receptor 0.0462 0.2628 0.3188
Trypanosoma cruzi hypothetical protein 0.0025 0.0062 0.1155
Loa Loa (eye worm) RGC/RGC protein kinase 0.0021 0.0039 0.0039
Echinococcus granulosus tyrosine protein kinase ABL1 0.0021 0.0039 0.0029
Loa Loa (eye worm) hypothetical protein 0.0021 0.0039 0.0039
Schistosoma mansoni plexin 0.017 0.0914 0.0918
Echinococcus multilocularis tyrosine protein kinase Fyn 0.0021 0.0039 0.0024
Trichomonas vaginalis AGC family protein kinase 0.0032 0.0104 0.0438
Trichomonas vaginalis AGC family protein kinase 0.0032 0.0104 0.0438
Schistosoma mansoni dynamin 0.0025 0.0062 0.0048
Schistosoma mansoni dynamin 0.0025 0.0062 0.0048
Brugia malayi Voltage-gated potassium channel, HERG (KCNH2)-related. C. elegans unc-103 ortholog 0.0036 0.0128 0.013
Loa Loa (eye worm) hypothetical protein 0.0273 0.152 0.1548
Brugia malayi Protein kinase domain containing protein 0.0021 0.0039 0.0039
Loa Loa (eye worm) hypothetical protein 0.0021 0.0039 0.0039
Chlamydia trachomatis pyruvate kinase 0.0069 0.0319 1
Trichomonas vaginalis conserved hypothetical protein 0.0025 0.0062 0.0158
Schistosoma mansoni rho gtpase activating protein 0.0025 0.0062 0.0048
Trichomonas vaginalis centaurin gamma, putative 0.0025 0.0062 0.0158
Loa Loa (eye worm) hypothetical protein 0.0049 0.0205 0.0209
Entamoeba histolytica ankyrin repeat protein 0.0021 0.0039 0.000000049527
Echinococcus multilocularis aurora kinase A 0.0066 0.03 0.0286
Schistosoma mansoni protein kinase 0.0066 0.03 0.0291
Entamoeba histolytica PH domain containing protein kinase, putative 0.0032 0.0104 0.0438
Loa Loa (eye worm) hypothetical protein 0.0025 0.0062 0.0063
Schistosoma mansoni niemann-pick C1 (NPC1) 0.011 0.0561 0.0557
Trypanosoma cruzi hypothetical protein 0.0025 0.0062 0.1155
Entamoeba histolytica Rho guanine nucleotide exchange factor, putative 0.0025 0.0062 0.0158
Schistosoma mansoni ap endonuclease 0.0023 0.0048 0.0034
Entamoeba histolytica hypothetical protein 0.0273 0.152 1
Trichomonas vaginalis centaurin/arf, putative 0.0025 0.0062 0.0158
Loa Loa (eye worm) abnormal chemotaxis protein 14 0.0046 0.0188 0.0191
Entamoeba histolytica acyl-CoA synthetase, putative 0.0049 0.0205 0.1121
Schistosoma mansoni fibrocystin l 0.0058 0.0253 0.0243
Echinococcus multilocularis tyrosine protein kinase Fyn 0.0021 0.0039 0.0024
Trichomonas vaginalis centaurin/arf, putative 0.0025 0.0062 0.0158
Loa Loa (eye worm) hypothetical protein 0.0273 0.152 0.1548
Brugia malayi GTP-ase activating protein for Arf containing protein 0.0025 0.0062 0.0063
Plasmodium vivax AP endonuclease (DNA-[apurinic or apyrimidinic site] lyase), putative 0.0023 0.0048 0.0346
Loa Loa (eye worm) PXA domain-containing protein 0.0273 0.152 0.1548
Echinococcus multilocularis tyrosine kinase 0.0021 0.0039 0.0024
Echinococcus multilocularis Regulator of G protein signaling 20 0.0273 0.152 0.1507
Mycobacterium ulcerans pyruvate kinase 0.0069 0.0319 1
Echinococcus granulosus regulator of G protein signaling 7 0.0273 0.152 0.1836
Schistosoma mansoni regulator of G protein signaling 0.0273 0.152 0.1535
Schistosoma mansoni vesicular amine transporter 0.0065 0.0295 0.0285
Schistosoma mansoni plexin 0.0302 0.1687 0.1706
Loa Loa (eye worm) TK/FER protein kinase 0.0021 0.0039 0.0039
Echinococcus multilocularis pyruvate kinase 0.0054 0.0234 0.0219
Trichomonas vaginalis AGC family protein kinase 0.0032 0.0104 0.0438
Schistosoma mansoni serine/threonine protein kinase 0.1291 0.7504 0.7642
Trypanosoma cruzi hypothetical protein 0.0025 0.0062 0.1155
Trypanosoma cruzi Serine/threonine-protein kinase NEK17, putative 0.0032 0.0104 0.2582
Trypanosoma cruzi ADP-ribosylation factor family, putative 0.0025 0.0062 0.1155
Echinococcus granulosus expressed protein 0.0273 0.152 0.1836
Echinococcus granulosus melanoma receptor tyrosine protein kinase 0.0021 0.0039 0.0029
Brugia malayi hypothetical protein 0.0062 0.0281 0.0286
Echinococcus granulosus tyrosine protein kinase Btk29A 0.0021 0.0039 0.0029
Schistosoma mansoni proto-oncogene tyrosine-protein kinase src 0.0021 0.0039 0.0024
Schistosoma mansoni pyruvate kinase 0.0069 0.0319 0.031
Entamoeba histolytica protein kinase domain containing protein 0.0079 0.0377 0.2286
Schistosoma mansoni serine/threonine-protein kinase 0.0032 0.0104 0.009
Onchocerca volvulus 0.0021 0.0039 0.000000026969
Trypanosoma brucei STE/STE11 serine/threonine-protein kinase, putative 0.0028 0.008 0.1774
Echinococcus multilocularis isocitrate dehydrogenase 2 (NADP+) 0.0034 0.0115 0.01
Echinococcus multilocularis protein kinase 0.0021 0.0039 0.0024
Plasmodium falciparum acylated pleckstrin-homology domain-containing protein, putative 0.0025 0.0062 0.0837
Schistosoma mansoni tyrosine protein kinase 0.0021 0.0039 0.0024
Brugia malayi Protein kinase domain containing protein 0.0021 0.0039 0.0039
Loa Loa (eye worm) RGS-3 protein 0.0273 0.152 0.1548
Trichomonas vaginalis regulator of G protein signaling 5, rgs5, putative 0.0273 0.152 1
Echinococcus granulosus Pleckstrin y 0.0025 0.0062 0.0057
Schistosoma mansoni ephrin receptor 0.0021 0.0039 0.0024
Trypanosoma brucei serine/threonine-protein kinase NrkA 0.0032 0.0104 0.2582
Schistosoma mansoni tyrosine protein kinase fes (fps) (ptk group IV) 0.0021 0.0039 0.0024
Brugia malayi Protein kinase domain containing protein 0.0021 0.0039 0.0039
Brugia malayi integrin-linked kinase 0.0021 0.0039 0.0039
Schistosoma mansoni proto-oncogene tyrosine-protein kinase src 0.0021 0.0039 0.0024
Trichomonas vaginalis conserved hypothetical protein 0.0025 0.0062 0.0158
Leishmania major protein kinase, putative 0.0066 0.03 0.9359
Echinococcus multilocularis tyrosine kinase 0.0021 0.0039 0.0024
Mycobacterium ulcerans acyl-CoA synthetase 0.0049 0.0205 0.6064
Loa Loa (eye worm) AUR protein kinase 0.0066 0.03 0.0306
Loa Loa (eye worm) G protein signaling regulator EGL-10 0.0273 0.152 0.1548
Schistosoma mansoni regulator of G protein signaling 0.0273 0.152 0.1535
Echinococcus granulosus basic fibroblast growth factor receptor 1 A 0.0021 0.0039 0.0029
Echinococcus multilocularis c src tyrosine kinase 0.0021 0.0039 0.0024
Entamoeba histolytica Rho guanine nucleotide exchange factor, putative 0.0025 0.0062 0.0158
Echinococcus granulosus serine/threonine protein kinase 0.0032 0.0104 0.0108
Echinococcus granulosus kinase suppressor of Ras 1 0.0021 0.0039 0.0029
Echinococcus granulosus pdz domain containing protein 0.0025 0.0062 0.0057
Schistosoma mansoni regulator of G protein signaling 17 19 20 (rgs17 19 20) 0.0273 0.152 0.1535
Trichomonas vaginalis AGC family protein kinase 0.0066 0.03 0.1767
Loa Loa (eye worm) TK/INSR protein kinase 0.0021 0.0039 0.0039
Echinococcus multilocularis retinal guanylyl cyclase 2 0.0021 0.0039 0.0024
Echinococcus multilocularis expressed protein 0.0273 0.152 0.1507
Brugia malayi Immunoglobulin I-set domain containing protein 0.0062 0.0281 0.0286
Echinococcus multilocularis guanine nucleotide binding protein G(s) subunit 0.0055 0.0239 0.0225
Echinococcus multilocularis tyrosine protein kinase Fps85D 0.0021 0.0039 0.0024
Echinococcus multilocularis heat shock protein 70 0.0021 0.0039 0.0024
Loa Loa (eye worm) TK protein kinase 0.0021 0.0039 0.0039
Echinococcus multilocularis dynamin 1 0.0025 0.0062 0.0047
Loa Loa (eye worm) hypothetical protein 0.0021 0.0039 0.0039
Onchocerca volvulus 0.0236 0.1305 0.4654
Echinococcus multilocularis Immunoglobulin 0.0062 0.0281 0.0266
Brugia malayi Pyruvate kinase, alpha/beta domain containing protein 0.0021 0.0037 0.0038
Loa Loa (eye worm) hypothetical protein 0.0021 0.0039 0.0039
Mycobacterium tuberculosis Probable fatty-acid-CoA ligase FadD5 (fatty-acid-CoA synthetase) (fatty-acid-CoA synthase) 0.0035 0.012 0.2633
Echinococcus granulosus roundabout 2 0.0062 0.0281 0.0324
Echinococcus multilocularis DNA (apurinic or apyrimidinic site) lyase 0.0023 0.0048 0.0033
Loa Loa (eye worm) TK protein kinase 0.0021 0.0039 0.0039
Trichomonas vaginalis AGC family protein kinase 0.0032 0.0104 0.0438
Echinococcus multilocularis tyrosine protein kinase csk 0.0021 0.0039 0.0024
Schistosoma mansoni serine/threonine protein kinase 0.0021 0.0039 0.0024
Brugia malayi plexin A 0.0359 0.2026 0.2064
Trypanosoma cruzi aurora B kinase, putative 0.0066 0.03 0.9359
Loa Loa (eye worm) TK/FAK protein kinase 0.0021 0.0039 0.0039
Mycobacterium ulcerans long-chain-fatty-acid--CoA ligase 0.0049 0.0205 0.6064
Brugia malayi Dynamin 0.0025 0.0062 0.0063
Giardia lamblia Kinase, NEK 0.0021 0.0039 0.00000026162
Echinococcus multilocularis kinase suppressor of Ras 1 0.0021 0.0039 0.0024
Loa Loa (eye worm) TK/EPH protein kinase 0.0021 0.0039 0.0039
Trichomonas vaginalis alpha chimerin, putative 0.0025 0.0062 0.0158
Entamoeba histolytica cell surface protease gp63, putative 0.0058 0.0253 0.1451
Trichomonas vaginalis AGC family protein kinase 0.0066 0.03 0.1767
Leishmania major protein kinase, putative,serine/threonine protein kinase, putative 0.0032 0.0104 0.2582
Echinococcus multilocularis DCC interacting protein 13 beta 0.0025 0.0062 0.0047
Brugia malayi serine/threonine protein kinase 6 0.0066 0.03 0.0306
Loa Loa (eye worm) hypothetical protein 0.0054 0.0233 0.0238
Echinococcus multilocularis protein tyrosine kinase 0.0021 0.0039 0.0024
Loa Loa (eye worm) TK/FER protein kinase 0.0021 0.0039 0.0039
Echinococcus multilocularis atrial natriuretic peptide receptor 1 0.0021 0.0039 0.0024
Echinococcus granulosus tyrosine protein kinase Src64B 0.0021 0.0039 0.0029
Loa Loa (eye worm) TKL/STKR/TYPE1 protein kinase 0.0021 0.0039 0.0039
Loa Loa (eye worm) hypothetical protein 0.0037 0.0131 0.0134
Schistosoma mansoni protein kinase 0.0028 0.008 0.0066
Loa Loa (eye worm) TK/FER protein kinase 0.0021 0.0039 0.0039
Echinococcus granulosus protein tyrosine kinase 0.0021 0.0039 0.0029
Brugia malayi Protein kinase domain containing protein 0.0021 0.0039 0.0039
Schistosoma mansoni pyruvate kinase 0.0069 0.0319 0.031
Schistosoma mansoni tyrosine kinase 0.0021 0.0039 0.0024
Brugia malayi GTPase-activator protein for Ras-like GTPase containing protein 0.0025 0.0062 0.0063
Entamoeba histolytica PH domain containing protein 0.0025 0.0062 0.0158
Echinococcus multilocularis Rho GTPase activating protein 24 0.0025 0.0062 0.0047
Echinococcus granulosus macrophage colony stimulating factor 1 receptor 0.0021 0.0039 0.0029
Trypanosoma cruzi PH domain containing protein, putative 0.0025 0.0062 0.1155
Trypanosoma cruzi phosphatidylinositol-4-phosphate 5-kinase, putative 0.0025 0.0062 0.1155
Trichomonas vaginalis AGC family protein kinase 0.0032 0.0104 0.0438
Echinococcus multilocularis tyrosine protein kinase csk 0.0021 0.0039 0.0024
Trichomonas vaginalis conserved hypothetical protein 0.0025 0.0062 0.0158
Trypanosoma cruzi isocitrate dehydrogenase, putative 0.0034 0.0115 0.2961
Trichomonas vaginalis AGC family protein kinase 0.0032 0.0104 0.0438
Echinococcus multilocularis insulin growth factor 1 receptor beta 0.0021 0.0039 0.0024
Loa Loa (eye worm) TK/KIN6 protein kinase 0.0021 0.0039 0.0039
Trichomonas vaginalis conserved hypothetical protein 0.0058 0.0253 0.1451
Echinococcus multilocularis exocyst complex component 2 0.0058 0.0253 0.0239
Mycobacterium ulcerans fatty-acid-CoA ligase 0.0049 0.0205 0.6064
Echinococcus granulosus tyrosine kinase 0.0021 0.0039 0.0029
Trichomonas vaginalis protein transport protein sec7, putative 0.0025 0.0062 0.0158
Schistosoma mansoni tyrosine protein kinase fes (fps) (ptk group IV) 0.0021 0.0039 0.0024
Loa Loa (eye worm) TK/CSK protein kinase 0.0021 0.0039 0.0039
Schistosoma mansoni ephrin receptor 0.0021 0.0039 0.0024
Brugia malayi hypothetical protein 0.0021 0.0039 0.0039
Echinococcus multilocularis pleckstrin y domain containing family A 0.0025 0.0062 0.0047
Echinococcus multilocularis tyrosine protein kinase Blk 0.0021 0.0039 0.0024
Onchocerca volvulus Putative neuronal RhoA GEF protein 0.0025 0.0062 0.0086
Loa Loa (eye worm) hypothetical protein 0.0108 0.0551 0.0561
Echinococcus multilocularis hypothetical protein 0.0132 0.0688 0.0674
Trichomonas vaginalis AGC family protein kinase 0.0032 0.0104 0.0438
Echinococcus multilocularis Oxysterol binding protein 11 0.0025 0.0062 0.0047
Loa Loa (eye worm) hypothetical protein 0.0031 0.01 0.0102
Schistosoma mansoni protein tyrosine kinase 0.0021 0.0039 0.0024
Toxoplasma gondii calcium dependent protein kinase CDPK8 0.0028 0.008 0.1478
Plasmodium vivax isocitrate dehydrogenase [NADP], mitochondrial, putative 0.0034 0.0115 0.2708
Trypanosoma cruzi rac serine-threonine kinase, putative 0.0032 0.0104 0.2582
Loa Loa (eye worm) hypothetical protein 0.0021 0.0039 0.0039
Entamoeba histolytica protein kinase, putative 0.0032 0.0104 0.0438
Entamoeba histolytica protein kinase, putative 0.0066 0.03 0.1767
Echinococcus multilocularis transcription factor collier 0.0058 0.0253 0.0239
Brugia malayi Pyruvate kinase, M2 isozyme 0.0069 0.0319 0.0325
Trichomonas vaginalis pyruvate kinase, putative 0.0069 0.0319 0.1893
Schistosoma mansoni tyrosine kinase 0.0021 0.0039 0.0024
Brugia malayi GTP-ase activating protein for Arf containing protein 0.0025 0.0062 0.0063
Loa Loa (eye worm) TK/FER protein kinase 0.0021 0.0039 0.0039
Entamoeba histolytica protein kinase, putative 0.0021 0.0039 0.000000049527
Plasmodium vivax calcium-dependent protein kinase 7, putative 0.0032 0.0104 0.2315
Plasmodium falciparum isocitrate dehydrogenase [NADP], mitochondrial 0.0034 0.0115 0.2708
Loa Loa (eye worm) hypothetical protein 0.0037 0.0131 0.0134
Schistosoma mansoni tyrosine kinase 0.0021 0.0039 0.0024
Brugia malayi Protein kinase domain containing protein 0.0021 0.0039 0.0039
Brugia malayi C-terminal src kinase protein 1 0.0021 0.0039 0.0039
Echinococcus multilocularis potassium voltage gated channel subfamily H 0.0036 0.0128 0.0113
Brugia malayi SRC-1 0.0021 0.0039 0.0039
Trichomonas vaginalis AGC family protein kinase 0.0032 0.0104 0.0438
Echinococcus multilocularis regulator of G protein signaling 7 0.0273 0.152 0.1507
Entamoeba histolytica hypothetical protein 0.0058 0.0253 0.1451
Loa Loa (eye worm) hypothetical protein 0.0132 0.0688 0.0701
Brugia malayi Regulator of G protein signaling domain containing protein 0.0273 0.152 0.1548
Schistosoma mansoni guanyl-nucleotide exchange factor 0.0025 0.0062 0.0048
Echinococcus multilocularis muscleblind protein 0.0149 0.0791 0.0777
Loa Loa (eye worm) protein kinase domain-containing protein 0.0021 0.0039 0.0039
Entamoeba histolytica acyl-coA synthetase, putative 0.0049 0.0205 0.1121
Leishmania major protein kinase, putative 0.0032 0.0104 0.2582
Loa Loa (eye worm) hypothetical protein 0.017 0.0914 0.0932
Brugia malayi Protein kinase domain containing protein 0.0021 0.0039 0.0039
Loa Loa (eye worm) TKL/RAF/KSR protein kinase 0.0021 0.0039 0.0039
Brugia malayi Protein kinase domain containing protein 0.0021 0.0039 0.0039
Schistosoma mansoni tyrosine kinase 0.0021 0.0039 0.0024
Loa Loa (eye worm) AGC/GRK/GRK protein kinase 0.1685 0.9815 1
Entamoeba histolytica protein kinase, putative 0.0032 0.0104 0.0438
Onchocerca volvulus Putative zinc finger protein 0.0025 0.0062 0.0086
Schistosoma mansoni tyrosine kinase 0.0021 0.0039 0.0024
Brugia malayi Protein kinase domain containing protein 0.0021 0.0039 0.0039
Trypanosoma cruzi protein kinase, putative 0.0021 0.0039 0.0347
Echinococcus multilocularis insulin receptor 0.0021 0.0039 0.0024
Loa Loa (eye worm) hypothetical protein 0.0062 0.0281 0.0286
Entamoeba histolytica Rho guanine nucleotide exchange factor, putative 0.0025 0.0062 0.0158
Entamoeba histolytica serine/threonine protein kinase 6, putative 0.0066 0.03 0.1767
Echinococcus multilocularis fibroblast growth factor receptor 4 0.0021 0.0039 0.0024
Loa Loa (eye worm) TK/KIN16 protein kinase 0.0083 0.0405 0.0412
Brugia malayi Guanylyl cyclase protein 23 0.0021 0.0039 0.0039
Schistosoma mansoni tyrosine kinase 0.0021 0.0039 0.0024
Entamoeba histolytica hypothetical protein, conserved domain containing 0.0025 0.0062 0.0158
Trichomonas vaginalis ribosomal protein S6 kinase, 90kD, polypeptide, putative 0.0032 0.0104 0.0438
Loa Loa (eye worm) hypothetical protein 0.0021 0.0039 0.0039
Trichomonas vaginalis hypothetical protein 0.0025 0.0062 0.0158
Echinococcus multilocularis actin binding protein anillin 0.0025 0.0062 0.0047
Echinococcus granulosus beta 1 syntrophin 0.0025 0.0062 0.0057
Echinococcus granulosus FERM and pleckstrin domain containing protein 0.0025 0.0062 0.0057
Loa Loa (eye worm) TK/FER protein kinase 0.0021 0.0039 0.0039
Trichomonas vaginalis pyruvate kinase, putative 0.0069 0.0319 0.1893
Leishmania major protein kinase, putative 0.0028 0.008 0.1774
Loa Loa (eye worm) hypothetical protein 0.0025 0.0062 0.0063
Echinococcus multilocularis dual specificity testis specific protein kinase 0.0028 0.008 0.0065
Plasmodium vivax pyruvate kinase, putative 0.0069 0.0319 1
Echinococcus granulosus semaphorin 1A 0.0132 0.0688 0.0821
Trichomonas vaginalis development and differentiation-enhancing factor, ddef, putative 0.0025 0.0062 0.0158
Echinococcus multilocularis regulator of G protein signaling 0.0273 0.152 0.1507
Schistosoma mansoni hypothetical protein 0.0045 0.0178 0.0166
Echinococcus granulosus dual specificity testis-specific protein kinase 0.0028 0.008 0.0079
Brugia malayi Plekhf2 protein 0.0025 0.0062 0.0063
Brugia malayi regulator of G-protein signaling rgs-7 0.0273 0.152 0.1548
Brugia malayi Protein kinase domain containing protein 0.0021 0.0039 0.0039
Plasmodium vivax serine/threonine protein kinase 6, putative 0.0066 0.03 0.9336
Onchocerca volvulus 0.003 0.009 0.0189
Brugia malayi hypothetical protein 0.0021 0.0039 0.0039
Leishmania major protein kinase, putative 0.0021 0.0039 0.0347
Entamoeba histolytica hypothetical protein 0.0032 0.0104 0.0438
Schistosoma mansoni tyrosine kinase 0.0021 0.0039 0.0024
Echinococcus granulosus histone lysine methyltransferase setb 0.003 0.009 0.0091
Trichomonas vaginalis AGC family protein kinase 0.0032 0.0104 0.0438
Loa Loa (eye worm) voltage and ligand gated potassium channel 0.0036 0.0128 0.013
Trichomonas vaginalis ap endonuclease, putative 0.0023 0.0048 0.0065
Schistosoma mansoni oxysterol-binding protein 1 0.0025 0.0062 0.0048
Loa Loa (eye worm) MH2 domain-containing protein 0.025 0.1387 0.1413
Trypanosoma brucei isocitrate dehydrogenase [NADP], mitochondrial precursor, putative 0.0034 0.0115 0.2961
Plasmodium falciparum acyl-CoA synthetase 0.0037 0.0131 0.3309
Echinococcus granulosus oxysterol binding protein 3 0.0025 0.0062 0.0057
Schistosoma mansoni hypothetical protein 0.0025 0.0062 0.0048
Mycobacterium ulcerans acyl-CoA synthetase 0.0049 0.0205 0.6064
Echinococcus granulosus activin receptor type 0.0028 0.008 0.0079
Echinococcus multilocularis histone lysine N methyltransferase SETMAR 0.003 0.009 0.0075
Schistosoma mansoni protein kinase 0.0021 0.0039 0.0024
Loa Loa (eye worm) hypothetical protein 0.0025 0.0062 0.0063
Mycobacterium leprae Probable pyruvate kinase PykA 0.0069 0.0319 1
Echinococcus multilocularis Immunoglobulin 0.0062 0.0281 0.0266
Schistosoma mansoni tyrosine kinase 0.0021 0.0039 0.0024
Schistosoma mansoni tyrosine kinase 0.0021 0.0039 0.0024
Echinococcus granulosus pyruvate kinase 0.0035 0.0122 0.0131
Loa Loa (eye worm) rho-GTPase-activating 0.0025 0.0062 0.0063
Leishmania major hypothetical protein, conserved 0.0021 0.0039 0.0347
Echinococcus granulosus activated cdc42 kinase 1 0.0021 0.0039 0.0029
Brugia malayi Cytohesin 3 0.0025 0.0062 0.0063
Schistosoma mansoni histone-lysine n-methyltransferase setb1 0.003 0.009 0.0076
Schistosoma mansoni goodpasture antigen-binding protein 0.0025 0.0062 0.0048
Echinococcus granulosus Arf GAP and Pleckstrin domain containing protein 0.0025 0.0062 0.0057
Loa Loa (eye worm) TKL/MLK/TAK1 protein kinase 0.0021 0.0039 0.0039
Entamoeba histolytica serine/threonine- protein kinase 6, putative 0.0066 0.03 0.1767
Echinococcus granulosus arf GAP with coiled coil ANK repeat and PH 0.0025 0.0062 0.0057
Trichomonas vaginalis protein transport protein sec7, putative 0.0025 0.0062 0.0158
Echinococcus multilocularis microtubule associated protein 2 0.0689 0.3963 0.3954
Brugia malayi Pleckstrin Homology Domain 0.0025 0.0062 0.0063
Mycobacterium ulcerans fatty-acid-CoA ligase 0.0037 0.0131 0.3542
Brugia malayi Probable exocyst complex component Sec5 0.0058 0.0253 0.0258
Loa Loa (eye worm) hypothetical protein 0.0062 0.0281 0.0286
Trichomonas vaginalis conserved hypothetical protein 0.0025 0.0062 0.0158
Echinococcus multilocularis G protein coupled receptor kinase 6 0.1412 0.821 0.8207
Trypanosoma cruzi Serine/threonine-protein kinase NEK17, putative 0.0032 0.0104 0.2582
Echinococcus granulosus oxysterol binding protein 9 0.0025 0.0062 0.0057
Echinococcus granulosus pyruvate kinase 0.0069 0.0319 0.0371
Loa Loa (eye worm) hypothetical protein 0.0021 0.0039 0.0039
Schistosoma mansoni protein kinase 0.0021 0.0039 0.0024
Schistosoma mansoni voltage-gated potassium channel 0.004 0.0148 0.0135
Brugia malayi bone morphogenetic protein type 1 receptor 0.0021 0.0039 0.0039
Trichomonas vaginalis ankyrin 2,3/unc44, putative 0.0025 0.0062 0.0158
Entamoeba histolytica pleckstrin homology (PH) domain containing protein 0.0025 0.0062 0.0158
Echinococcus multilocularis pyruvate kinase 0.0035 0.0122 0.0107
Mycobacterium tuberculosis Probable chain -fatty-acid-CoA ligase FadD13 (fatty-acyl-CoA synthetase) 0.0049 0.0205 0.5777
Loa Loa (eye worm) hypothetical protein 0.0273 0.152 0.1548
Plasmodium vivax conserved Plasmodium protein, unknown function 0.0025 0.0062 0.0837
Echinococcus multilocularis geminin 0.0364 0.2057 0.2045
Plasmodium vivax PH domain containing protein 0.0025 0.0062 0.0837
Toxoplasma gondii protein kinase domain-containing protein 0.0032 0.0104 0.2315
Entamoeba histolytica hypothetical protein, conserved 0.0025 0.0062 0.0158
Schistosoma mansoni hypothetical protein 0.0025 0.0062 0.0048
Trichomonas vaginalis 3-phosphoinositide dependent protein kinase-1, putative 0.0032 0.0104 0.0438
Brugia malayi MH2 domain containing protein 0.0017 0.0015 0.0015
Echinococcus multilocularis FERM and pleckstrin domain containing protein 0.0025 0.0062 0.0047
Plasmodium falciparum conserved Plasmodium protein, unknown function 0.0025 0.0062 0.0837
Echinococcus granulosus regulator of G protein signaling 3 0.0273 0.152 0.1836
Echinococcus granulosus insulin receptor 0.0021 0.0039 0.0029
Echinococcus multilocularis receptor type guanylyl cyclase 0.0021 0.0039 0.0024
Brugia malayi Isocitrate dehydrogenase 0.0034 0.0115 0.0117
Trypanosoma cruzi hypothetical protein 0.0025 0.0062 0.1155
Leishmania major 4-coumarate:coa ligase-like protein 0.0049 0.0205 0.6064
Schistosoma mansoni protein kinase 0.0021 0.0039 0.0024
Echinococcus multilocularis basement membrane specific heparan sulfate 0.0062 0.0281 0.0266
Loa Loa (eye worm) TK/FER protein kinase 0.0021 0.0039 0.0039
Onchocerca volvulus Pyruvate kinase homolog 0.0069 0.0319 0.1031
Schistosoma mansoni NADP-specific isocitrate dehydrogenase 0.0034 0.0115 0.0101
Echinococcus granulosus integrin linked protein kinase 0.0021 0.0039 0.0029
Loa Loa (eye worm) pyruvate kinase 0.0069 0.0319 0.0325
Brugia malayi MH1 domain containing protein 0.0017 0.0015 0.0015
Brugia malayi Variant SH3 domain containing protein 0.0025 0.0062 0.0063
Echinococcus granulosus tyrosine protein kinase Blk 0.0021 0.0039 0.0029
Trichomonas vaginalis AGC family protein kinase 0.0032 0.0104 0.0438
Trichomonas vaginalis conserved hypothetical protein 0.0058 0.0253 0.1451
Echinococcus multilocularis roundabout 2 0.0062 0.0281 0.0266
Brugia malayi Probable tyrosine-protein kinase kin-31 0.0021 0.0039 0.0039
Echinococcus granulosus tyrosine protein kinase Srms 0.0021 0.0039 0.0029
Loa Loa (eye worm) hypothetical protein 0.003 0.009 0.0092
Onchocerca volvulus 0.0025 0.0062 0.0086
Loa Loa (eye worm) hypothetical protein 0.0302 0.1687 0.1719
Trypanosoma cruzi PH domain containing protein, putative 0.0025 0.0062 0.1155
Toxoplasma gondii phosphatidylinositol transfer protein 0.0025 0.0062 0.0837
Toxoplasma gondii pyruvate kinase PyK1 0.0069 0.0319 1
Trichomonas vaginalis TKL family protein kinase 0.0021 0.0039 0.000000049527
Trypanosoma brucei protein kinase, putative 0.0028 0.008 0.1774
Brugia malayi Sema domain containing protein 0.0132 0.0688 0.0701
Echinococcus multilocularis protein dispatched 1 0.0053 0.0226 0.0212
Trypanosoma cruzi Protein kinase B 0.0032 0.0104 0.2582
Entamoeba histolytica hypothetical protein 0.0058 0.0253 0.1451
Echinococcus multilocularis ras specific guanine nucleotide releasing factor 0.0025 0.0062 0.0047
Echinococcus multilocularis Niemann Pick C1 protein 0.0108 0.0551 0.0537
Trichomonas vaginalis conserved hypothetical protein 0.0058 0.0253 0.1451
Echinococcus granulosus retinal guanylyl cyclase 2 0.0021 0.0039 0.0029
Echinococcus granulosus Immunoglobulin 0.0062 0.0281 0.0324
Echinococcus granulosus tyrosine protein kinase csk 0.0021 0.0039 0.0029
Brugia malayi Probable G protein-coupled receptor kinase F19C6.1, putative 0.1685 0.9815 1
Plasmodium vivax acyl-CoA synthetase, putative 0.0037 0.0131 0.3309
Echinococcus granulosus pleckstrin y domain containing family A 0.0025 0.0062 0.0057
Trichomonas vaginalis conserved hypothetical protein 0.0025 0.0062 0.0158
Echinococcus granulosus ephrin type A receptor 4 A 0.0021 0.0039 0.0029
Loa Loa (eye worm) hypothetical protein 0.0025 0.0062 0.0063
Schistosoma mansoni src-type protein tyrosine kinase-related 0.0021 0.0039 0.0024
Echinococcus granulosus geminin 0.0364 0.2057 0.2491
Brugia malayi proto-oncogene tyrosine-protein kinase FER 0.0021 0.0039 0.0039
Echinococcus granulosus 3'partial|retinal guanylyl cyclase 2 0.0021 0.0039 0.0029
Echinococcus granulosus tyrosine protein kinase Btk29A 0.0021 0.0039 0.0029
Loa Loa (eye worm) hypothetical protein 0.0062 0.0281 0.0286
Entamoeba histolytica tyrosin kinase, putative 0.0079 0.0377 0.2286
Trichomonas vaginalis ankyrin repeat-containing protein, putative 0.0025 0.0062 0.0158
Echinococcus granulosus Rho GTPase activating protein 24 0.0025 0.0062 0.0057
Loa Loa (eye worm) hypothetical protein 0.0025 0.0062 0.0063
Trypanosoma cruzi hypothetical protein 0.0025 0.0062 0.1155
Schistosoma mansoni serine/threonine protein kinase 0.0021 0.0039 0.0024
Loa Loa (eye worm) hypothetical protein 0.0058 0.0253 0.0258
Echinococcus multilocularis arf GAP with coiled coil, ANK repeat and PH 0.0025 0.0062 0.0047
Echinococcus multilocularis natriuretic peptide receptor 1 0.0021 0.0039 0.0024
Echinococcus granulosus regulator of G protein signaling 7 0.0273 0.152 0.1836
Loa Loa (eye worm) cytochrome P450 family protein 0.0019 0.0029 0.0029
Brugia malayi regulator of G-protein signaling egl-10 0.0273 0.152 0.1548
Loa Loa (eye worm) PH domain-containing protein 0.0025 0.0062 0.0063
Trichomonas vaginalis conserved hypothetical protein 0.0273 0.152 1
Loa Loa (eye worm) transcription factor SMAD2 0.025 0.1387 0.1413
Echinococcus granulosus tyrosine kinase 0.0021 0.0039 0.0029
Leishmania major rac serine-threonine kinase, putative,protein kinase, putative 0.0032 0.0104 0.2582
Brugia malayi Protein kinase domain containing protein 0.0021 0.0039 0.0039
Schistosoma mansoni goodpasture antigen-binding protein 0.0025 0.0062 0.0048
Mycobacterium ulcerans exodeoxyribonuclease III protein XthA 0.0023 0.0048 0.0681
Giardia lamblia Pyruvate kinase 0.0035 0.0122 0.2984
Brugia malayi Oxysterol-binding protein 0.0025 0.0062 0.0063
Loa Loa (eye worm) hypothetical protein 0.0057 0.0249 0.0254
Loa Loa (eye worm) GTP-binding regulatory protein Gs alpha-S chain 0.0055 0.0239 0.0244
Loa Loa (eye worm) TK/EGFR protein kinase 0.0021 0.0039 0.0039
Plasmodium vivax pyruvate kinase 2, putative 0.0035 0.0122 0.2984
Brugia malayi AMP-binding enzyme family protein 0.0049 0.0205 0.0209
Entamoeba histolytica hypothetical protein 0.0273 0.152 1
Loa Loa (eye worm) TK/FER protein kinase 0.0021 0.0039 0.0039
Loa Loa (eye worm) hypothetical protein 0.0058 0.0253 0.0258
Loa Loa (eye worm) GTP-ase activating protein for Arf containing protein 0.0025 0.0062 0.0063
Schistosoma mansoni serine/threonine-protein kinase 0.0032 0.0104 0.009
Echinococcus granulosus defective proboscis extension response 0.0062 0.0281 0.0324
Loa Loa (eye worm) hypothetical protein 0.0132 0.0688 0.0701
Loa Loa (eye worm) GTP-ase activating protein for Arf containing protein 0.0025 0.0062 0.0063
Echinococcus multilocularis semaphorin 5B 0.0132 0.0688 0.0674
Echinococcus multilocularis histone lysine methyltransferase setb histone lysine methyltransferase eggless 0.003 0.009 0.0075
Echinococcus granulosus G protein coupled receptor kinase 1 0.1018 0.5899 0.718
Echinococcus multilocularis plexin a4 0.0359 0.2026 0.2014
Echinococcus granulosus Niemann Pick C1 protein 0.0155 0.0824 0.0987
Loa Loa (eye worm) TKL/MLK/ILK protein kinase 0.0021 0.0039 0.0039
Schistosoma mansoni tyrosine kinase 0.0021 0.0039 0.0024
Echinococcus multilocularis regulator of G protein signaling 7 0.0273 0.152 0.1507
Giardia lamblia Pyruvate kinase 0.0069 0.0319 1
Loa Loa (eye worm) TK protein kinase 0.0021 0.0039 0.0039
Loa Loa (eye worm) hypothetical protein 0.0062 0.0281 0.0286

Activities

Activity type Activity value Assay description Source Reference
Potency (functional) 10 uM PubChem BioAssay. qHTS Assay for Inhibitors of the Human Apurinic/apyrimidinic Endonuclease 1 (APE1). (Class of assay: confirmatory) ChEMBL. No reference
Potency (functional) 11.2202 uM PubChem BioAssay. qHTS for Agonist of gsp, the Etiologic Mutation Responsible for Fibrous Dysplasia/McCune-Albright Syndrome: qHTS. (Class of assay: confirmatory) ChEMBL. No reference
Potency (functional) 11.6891 uM PUBCHEM_BIOASSAY: Primary qHTS for delayed death inhibitors of the malarial parasite plastid, 48 hour incubation. (Class of assay: confirmatory) [Related pubchem assays (depositor defined):AID488752, AID488774, AID504848, AID504850] ChEMBL. No reference
Potency (functional) 14.7157 uM PUBCHEM_BIOASSAY: Primary qHTS for delayed death inhibitors of the malarial parasite plastid, 96 hour incubation. (Class of assay: confirmatory) [Related pubchem assays (depositor defined):AID488745, AID488752, AID488774, AID504848, AID504850] ChEMBL. No reference
Potency (functional) 89.1251 uM PUBCHEM_BIOASSAY: qHTS for Inhibitors of Polymerase Iota. (Class of assay: confirmatory) [Related pubchem assays (depositor defined):AID588623] ChEMBL. No reference
Potency (functional) 141.2538 uM PUBCHEM_BIOASSAY: qHTS Assay for Inhibitors of the Phosphatase Activity of Eya2. (Class of assay: confirmatory) [Related pubchem assays (depositor defined):AID488939] ChEMBL. No reference

Phenotypes

Whole-cell/tissue/organism interactions

Species name Source Reference Is orphan
Plasmodium falciparum ChEMBL23

Many chemical entities in TDR Targets come from high-throughput screenings with whole cells or tissue samples, and not all assayed compounds have been tested against a single a single target protein, probably because they get ruled out during screening process. Even if these compounds may have not been of interest in the original screening, they may come as interesting leads for other screening assays. Furthermore, we may be able to propose drug-target associations using chemical similarities and network patterns.

Annotated phenotypes:

We have no manually annotated phenotypes for this drug. What does this mean? / Care to help?
In TDR Targets, information about phenotypes that are caused by drugs, or by genetic manipulation of cells (e.g. gene knockouts or knockdowns) is manually curated from the literature. These descriptions help to describe the potential of the target for drug development. If no information is available for this gene or if the information is incomplete, this may mean that i) the papers containing this information either appeared after the curation effort for this organism was carried out or they were inadvertently missed by curators; or that ii) the curation effort for this organism has not yet started.
 
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External resources for this compound

Bibliographic References

No literature references available for this target.

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