Detailed information for compound 1299134

Basic information

Technical information
  • TDR Targets ID: 1299134
  • Name: 4-[(3-methylthiophen-2-yl)methylidene]-2-prop -2-enylsulfanyl-1,3-thiazol-5-one
  • MW: 281.417 | Formula: C12H11NOS3
  • H donors: 0 H acceptors: 1 LogP: 4.11 Rotable bonds: 4
    Rule of 5 violations (Lipinski): 1
  • SMILES: C=CCSC1=N/C(=C\c2sccc2C)/C(=O)S1
  • InChi: 1S/C12H11NOS3/c1-3-5-16-12-13-9(11(14)17-12)7-10-8(2)4-6-15-10/h3-4,6-7H,1,5H2,2H3/b9-7-
  • InChiKey: PMEYLUCHFDVPIB-CLFYSBASSA-N  

Network

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Synonyms

  • (4Z)-4-[(3-methylthiophen-2-yl)methylidene]-2-prop-2-enylsulfanyl-1,3-thiazol-5-one
  • (4Z)-2-allylsulfanyl-4-[(3-methyl-2-thienyl)methylene]thiazol-5-one
  • 2-allylsulfanyl-4-[(3-methyl-2-thienyl)methylene]thiazol-5-one
  • (4Z)-2-(allylthio)-4-[(3-methyl-2-thienyl)methylene]-5-thiazolone
  • 2-(allylthio)-4-[(3-methyl-2-thienyl)methylene]-5-thiazolone
  • (4Z)-2-(allylthio)-4-[(3-methyl-2-thienyl)methylene]thiazol-5-one
  • 2-(allylthio)-4-[(3-methyl-2-thienyl)methylene]thiazol-5-one
  • 2-(allylthio)-4-[(3-methyl-2-thienyl)methylene]-1,3-thiazol-5(4H)-one
  • MLS000575975
  • SMR000197006
  • ZINC03001806

Targets

Known targets for this compound

Species Target name Source Bibliographic reference
Homo sapiens snurportin 1 No references
Mus musculus RAR-related orphan receptor gamma Starlite/ChEMBL No references
Homo sapiens RAN, member RAS oncogene family No references
Homo sapiens karyopherin (importin) beta 1 No references

Predicted pathogen targets for this compound

By orthology
Species Potential target Known druggable target/s Ortholog Group
Echinococcus granulosus importin subunit beta 1 Get druggable targets OG5_127843 All targets in OG5_127843
Echinococcus granulosus GTP binding nuclear protein Ran Get druggable targets OG5_127514 All targets in OG5_127514
Trypanosoma congolense importin beta-1 subunit, putative Get druggable targets OG5_127843 All targets in OG5_127843
Leishmania braziliensis GTP-binding protein, putative Get druggable targets OG5_127514 All targets in OG5_127514
Toxoplasma gondii HEAT repeat-containing protein Get druggable targets OG5_127843 All targets in OG5_127843
Plasmodium knowlesi GTP-binding nuclear protein RAN/TC4, putative Get druggable targets OG5_127514 All targets in OG5_127514
Trichomonas vaginalis importin beta-1, putative Get druggable targets OG5_127843 All targets in OG5_127843
Schistosoma mansoni ran Get druggable targets OG5_127514 All targets in OG5_127514
Schistosoma mansoni hypothetical protein Get druggable targets OG5_131808 All targets in OG5_131808
Trypanosoma cruzi GTP-binding nuclear protein rtb2, putative Get druggable targets OG5_127514 All targets in OG5_127514
Echinococcus granulosus snurportin 1 Get druggable targets OG5_131808 All targets in OG5_131808
Trypanosoma brucei gambiense GTP-binding nuclear protein rtb2, putative Get druggable targets OG5_127514 All targets in OG5_127514
Theileria parva importin beta, putative Get druggable targets OG5_127843 All targets in OG5_127843
Brugia malayi Importin beta-1 subunit Get druggable targets OG5_127843 All targets in OG5_127843
Candida albicans karyopherin-beta Get druggable targets OG5_127843 All targets in OG5_127843
Plasmodium berghei importin beta, putative Get druggable targets OG5_127843 All targets in OG5_127843
Schistosoma mansoni importin beta-1 Get druggable targets OG5_127843 All targets in OG5_127843
Leishmania donovani importin beta-1 subunit, putative Get druggable targets OG5_127843 All targets in OG5_127843
Neospora caninum GTP-binding nuclear protein Ran, related Get druggable targets OG5_127514 All targets in OG5_127514
Cryptosporidium hominis importin-beta2 Get druggable targets OG5_127843 All targets in OG5_127843
Plasmodium falciparum GTP-binding nuclear protein RAN/TC4 Get druggable targets OG5_127514 All targets in OG5_127514
Trypanosoma brucei importin beta-1 subunit, putative Get druggable targets OG5_127843 All targets in OG5_127843
Entamoeba histolytica hypothetical protein Get druggable targets OG5_127843 All targets in OG5_127843
Candida albicans karyopherin-beta Get druggable targets OG5_127843 All targets in OG5_127843
Brugia malayi RNA, U transporter 1 Get druggable targets OG5_131808 All targets in OG5_131808
Leishmania major importin beta-1 subunit, putative Get druggable targets OG5_127843 All targets in OG5_127843
Trypanosoma cruzi GTP-binding nuclear protein rtb2, putative Get druggable targets OG5_127514 All targets in OG5_127514
Schistosoma mansoni ran Get druggable targets OG5_127514 All targets in OG5_127514
Cryptosporidium hominis GTP-binding nuclear protein ran/tc4 Get druggable targets OG5_127514 All targets in OG5_127514
Loa Loa (eye worm) hypothetical protein Get druggable targets OG5_127843 All targets in OG5_127843
Plasmodium yoelii importin beta-1 subunit Get druggable targets OG5_127843 All targets in OG5_127843
Babesia bovis GTP-binding nuclear protein Ran Get druggable targets OG5_127514 All targets in OG5_127514
Candida albicans Ran, Ras family GTP-binding protein Get druggable targets OG5_127514 All targets in OG5_127514
Plasmodium yoelii GTP-binding nuclear protein ran/tc4 Get druggable targets OG5_127514 All targets in OG5_127514
Plasmodium knowlesi importin beta, putative Get druggable targets OG5_127843 All targets in OG5_127843
Theileria parva GTP-binding nuclear protein ran, putative Get druggable targets OG5_127514 All targets in OG5_127514
Leishmania donovani GTP-binding protein, putative Get druggable targets OG5_127514 All targets in OG5_127514
Entamoeba histolytica Ran family GTPase Get druggable targets OG5_127514 All targets in OG5_127514
Cryptosporidium parvum importin/karyopherin Get druggable targets OG5_127843 All targets in OG5_127843
Trypanosoma brucei GTP-binding nuclear protein rtb2, putative Get druggable targets OG5_127514 All targets in OG5_127514
Babesia bovis importin beta subunit, putative Get druggable targets OG5_127843 All targets in OG5_127843
Leishmania major GTP-binding protein, putative Get druggable targets OG5_127514 All targets in OG5_127514
Trypanosoma cruzi importin beta-1 subunit, putative Get druggable targets OG5_127843 All targets in OG5_127843
Cryptosporidium parvum GTP-binding nuclear protein ran/tc4 Get druggable targets OG5_127514 All targets in OG5_127514
Trichomonas vaginalis ran, putative Get druggable targets OG5_127514 All targets in OG5_127514
Loa Loa (eye worm) nucleolar RNA-associated protein alpha Get druggable targets OG5_131808 All targets in OG5_131808
Leishmania mexicana importin beta-1 subunit, putative Get druggable targets OG5_127843 All targets in OG5_127843
Loa Loa (eye worm) GTP-binding nuclear protein RAN/TC4 Get druggable targets OG5_127514 All targets in OG5_127514
Trypanosoma brucei gambiense importin beta-1 subunit, putative Get druggable targets OG5_127843 All targets in OG5_127843
Echinococcus multilocularis GTP binding nuclear protein Ran Get druggable targets OG5_127514 All targets in OG5_127514
Trypanosoma congolense GTP-binding nuclear protein rtb2, putative Get druggable targets OG5_127514 All targets in OG5_127514
Leishmania braziliensis importin beta-1 subunit, putative Get druggable targets OG5_127843 All targets in OG5_127843
Neospora caninum hypothetical protein Get druggable targets OG5_127843 All targets in OG5_127843
Trichomonas vaginalis Importin beta-1 subunit, putative Get druggable targets OG5_127843 All targets in OG5_127843
Trypanosoma brucei importin beta-1 subunit, putative Get druggable targets OG5_127843 All targets in OG5_127843
Plasmodium vivax importin-beta 2, putative Get druggable targets OG5_127843 All targets in OG5_127843
Plasmodium berghei GTP-binding nuclear protein RAN/TC4, putative Get druggable targets OG5_127514 All targets in OG5_127514
Trichomonas vaginalis Importin beta-1 subunit, putative Get druggable targets OG5_127843 All targets in OG5_127843
Leishmania mexicana GTP-binding protein, putative Get druggable targets OG5_127514 All targets in OG5_127514
Toxoplasma gondii GTP-binding nuclear protein ran/tc4 Get druggable targets OG5_127514 All targets in OG5_127514
Schistosoma japonicum ko:K07936 GTP-binding nuclear protein Ran, putative Get druggable targets OG5_127514 All targets in OG5_127514
Schistosoma japonicum Snurportin-1, putative Get druggable targets OG5_131808 All targets in OG5_131808
Leishmania infantum GTP-binding protein, putative Get druggable targets OG5_127514 All targets in OG5_127514
Candida albicans Ran, Ras family GTP-binding protein Get druggable targets OG5_127514 All targets in OG5_127514
Leishmania infantum importin beta-1 subunit, putative Get druggable targets OG5_127843 All targets in OG5_127843
Echinococcus multilocularis snurportin 1 Get druggable targets OG5_131808 All targets in OG5_131808
Plasmodium vivax GTP-binding nuclear protein RAN/TC4, putative Get druggable targets OG5_127514 All targets in OG5_127514
Giardia lamblia GTP-binding nuclear protein RAN/TC4 Get druggable targets OG5_127514 All targets in OG5_127514
Brugia malayi GTP-binding nuclear protein RAN/TC4 Get druggable targets OG5_127514 All targets in OG5_127514
Echinococcus multilocularis importin subunit beta 1 Get druggable targets OG5_127843 All targets in OG5_127843
Schistosoma japonicum Importin subunit beta-1, putative Get druggable targets OG5_127843 All targets in OG5_127843
Plasmodium falciparum importin beta, putative Get druggable targets OG5_127843 All targets in OG5_127843
Schistosoma japonicum Importin subunit beta, putative Get druggable targets OG5_127843 All targets in OG5_127843

By sequence similarity to non orthologous known druggable targets
No druggable targets predicted by sequence similarity

Obtained from network model

Ranking Plot


Putative Targets List


Species Potential target Raw Global Species
Toxoplasma gondii C-5 cytosine-specific DNA methylase superfamily protein 0.002 0.0049 0.0089
Schistosoma mansoni hypothetical protein 0.0927 0.5244 1
Trypanosoma cruzi phosphatidylinositol 3-related kinase, putative 0.0018 0.0039 0.0627
Onchocerca volvulus 0.0015 0.0023 0.007
Loa Loa (eye worm) hypothetical protein 0.0012 0.0005 0.0007
Schistosoma mansoni chromodomain helicase DNA binding protein 0.0013 0.0009 0.0017
Brugia malayi Nuclear hormone receptor family member nhr-31 0.0012 0.0005 0.0007
Echinococcus granulosus glycyl tRNA synthetase 0.0019 0.0045 0.0085
Entamoeba histolytica Ran family GTPase 0.0026 0.0081 0.0415
Trypanosoma brucei threonyl-tRNA synthetase, putative 0.0019 0.0045 0.0717
Trypanosoma cruzi Aminoacyl-tRNA editing domain containing protein, putative 0.0017 0.0032 0.0508
Echinococcus granulosus serotonin receptor 0.0015 0.0023 0.0044
Echinococcus granulosus chromodomain helicase DNA binding protein 4 0.0017 0.003 0.0058
Schistosoma mansoni tar DNA-binding protein 0.0066 0.0314 0.0598
Loa Loa (eye worm) hypothetical protein 0.0015 0.0023 0.0039
Trypanosoma brucei Lanosterol 14-alpha demethylase 0.0014 0.0016 0.0257
Onchocerca volvulus 0.0054 0.0241 0.0883
Toxoplasma gondii sugar transporter ST1 0.0048 0.021 0.0383
Trichomonas vaginalis Importin beta-1 subunit, putative 0.0028 0.0096 0.0357
Echinococcus multilocularis G-protein coupled receptor, putative 0.0015 0.0023 0.0023
Brugia malayi gonadotropin-releasing hormone receptor 2 0.0015 0.0023 0.0039
Trypanosoma brucei calcium/calmodulin-dependent protein kinase, putative 0.0105 0.0533 0.8624
Brugia malayi Corticotropin releasing factor receptor 2 precursor, putative 0.0278 0.1527 0.2584
Schistosoma mansoni biogenic amine (5HT) receptor 0.0015 0.0023 0.0043
Loa Loa (eye worm) nucleolar RNA-associated protein alpha 0.0372 0.2063 0.349
Loa Loa (eye worm) acetyltransferase 0.0157 0.0833 0.1409
Mycobacterium tuberculosis Probable chain -fatty-acid-CoA ligase FadD13 (fatty-acyl-CoA synthetase) 0.0027 0.0089 0.0516
Entamoeba histolytica hypothetical protein 0.0013 0.0009 0.0044
Loa Loa (eye worm) hypothetical protein 0.0015 0.0023 0.0039
Loa Loa (eye worm) hypothetical protein 0.0015 0.0023 0.0039
Onchocerca volvulus Neuropeptide F receptor homolog 0.0015 0.0023 0.007
Onchocerca volvulus 0.0043 0.0182 0.0662
Loa Loa (eye worm) CAMK/CAMK2 protein kinase 0.0105 0.0533 0.0902
Trichomonas vaginalis sugar transporter, putative 0.0048 0.021 0.0779
Loa Loa (eye worm) hypothetical protein 0.019 0.1023 0.1731
Mycobacterium leprae PROBABLE FATTY-ACID-CoA LIGASE FADD7 (FATTY-ACID-CoA SYNTHETASE) (FATTY-ACID-CoA SYNTHASE) 0.0027 0.0089 0.145
Giardia lamblia Hexose transporter 0.0048 0.021 0.1073
Plasmodium falciparum histone acetyltransferase GCN5 0.0042 0.0177 0.0214
Brugia malayi neuropeptide F receptor 0.0015 0.0023 0.0039
Trypanosoma brucei glucose transporter, putative 0.0106 0.0541 0.8748
Trichomonas vaginalis chromodomain helicase DNA binding protein, putative 0.0028 0.0094 0.0347
Trichomonas vaginalis sugar transporter, putative 0.0048 0.021 0.0779
Schistosoma mansoni ancient conserved domain protein 2 (cyclin m2) 0.0015 0.0023 0.0043
Echinococcus granulosus chromobox protein 1 0.0079 0.039 0.0743
Loa Loa (eye worm) hypothetical protein 0.0015 0.0023 0.0039
Loa Loa (eye worm) hypothetical protein 0.0275 0.1508 0.2551
Echinococcus granulosus General substrate transporter 0.0294 0.1615 0.308
Plasmodium vivax CDK-related protein kinase 6, putative 0.145 0.8233 1
Echinococcus granulosus g protein coupled receptor 0.0015 0.0023 0.0044
Echinococcus multilocularis histone lysine N methyltransferase SETMAR 0.0062 0.0288 0.0288
Trichomonas vaginalis PIKK family atypical protein kinase 0.0018 0.0039 0.0145
Echinococcus granulosus GPCR family 2 0.0088 0.0439 0.0836
Loa Loa (eye worm) hypothetical protein 0.0015 0.0023 0.0039
Echinococcus multilocularis g protein coupled receptor 0.0015 0.0023 0.0023
Trichomonas vaginalis conserved hypothetical protein 0.0048 0.021 0.0779
Echinococcus granulosus tachykinin peptides receptor 99D 0.0015 0.0023 0.0044
Loa Loa (eye worm) hypothetical protein 0.0015 0.0023 0.0039
Echinococcus multilocularis jumonji domain containing protein 0.0041 0.017 0.017
Loa Loa (eye worm) hypothetical protein 0.002 0.005 0.0085
Leishmania major threonyl-tRNA synthetase, putative 0.0019 0.0045 0.0715
Treponema pallidum threonyl-tRNA synthetase 0.0019 0.0045 0.3127
Trichomonas vaginalis glucose transporter, putative 0.0106 0.0541 0.2014
Loa Loa (eye worm) hypothetical protein 0.0041 0.017 0.0287
Trichomonas vaginalis PIKK family atypical protein kinase 0.0018 0.0039 0.0145
Echinococcus granulosus RUN 0.0043 0.0182 0.0347
Trichomonas vaginalis chromobox protein, putative 0.0013 0.0009 0.0033
Echinococcus granulosus glutamyl tRNA synthetase cytoplasmic 0.0102 0.0521 0.0994
Loa Loa (eye worm) cytochrome P450 family protein 0.0014 0.0016 0.0027
Trypanosoma cruzi Aminoacyl-tRNA editing domain containing protein, putative 0.0017 0.0032 0.0508
Trichomonas vaginalis D-aminoacylase, putative 0.0041 0.017 0.0631
Toxoplasma gondii PHD-finger domain-containing protein 0.003 0.0104 0.0189
Trypanosoma cruzi phosphatidylinositol kinase related protein, putative 0.0018 0.0039 0.063
Brugia malayi Serotonin receptor 0.0015 0.0023 0.0039
Echinococcus granulosus diuretic hormone 44 receptor GPRdih2 0.0088 0.0439 0.0836
Plasmodium vivax importin-beta 2, putative 0.0035 0.0134 0.0162
Schistosoma mansoni mixed-lineage leukemia protein mll 0.014 0.0738 0.1407
Mycobacterium tuberculosis Probable fatty-acid-CoA ligase FadD5 (fatty-acid-CoA synthetase) (fatty-acid-CoA synthase) 0.0019 0.0044 0.0196
Schistosoma mansoni tar DNA-binding protein 0.0066 0.0314 0.0598
Schistosoma mansoni amine GPCR 0.0015 0.0023 0.0043
Schistosoma mansoni biogenic amine receptor 0.0015 0.0023 0.0043
Onchocerca volvulus 0.0015 0.0023 0.007
Schistosoma mansoni glutamyl-tRNA synthetase cytoplasmic (glutamate--tRNA ligase) (glurs) 0.0102 0.0521 0.0993
Trichomonas vaginalis conserved hypothetical protein 0.0045 0.019 0.0705
Mycobacterium tuberculosis Probable lipase LipE 0.0041 0.017 0.1081
Loa Loa (eye worm) GTP-binding nuclear protein RAN/TC4 0.0026 0.0081 0.0137
Brugia malayi GnHR receptor homolog 0.0015 0.0023 0.0039
Brugia malayi hypothetical protein 0.0015 0.0023 0.0039
Toxoplasma gondii GTP-binding nuclear protein ran/tc4 0.0026 0.0081 0.0148
Loa Loa (eye worm) helicase 0.0013 0.0009 0.0015
Brugia malayi Phosphatidylinositol 3- and 4-kinase family protein 0.0018 0.0039 0.0066
Loa Loa (eye worm) hypothetical protein 0.0015 0.0023 0.0039
Brugia malayi Pre-SET motif family protein 0.0062 0.0288 0.0487
Schistosoma mansoni biogenic amine (5HT) receptor 0.0015 0.0023 0.0043
Echinococcus multilocularis phosphatidylinositol 3 and 4 kinase 0.0018 0.0039 0.0039
Brugia malayi F/Y-rich N-terminus family protein 0.0032 0.0116 0.0196
Trichomonas vaginalis conserved hypothetical protein 0.0015 0.0019 0.007
Onchocerca volvulus 0.0013 0.0009 0.0017
Mycobacterium ulcerans hypothetical protein 0.0017 0.0032 0.0848
Echinococcus granulosus importin subunit beta 1 0.0035 0.0134 0.0256
Schistosoma mansoni Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) 0.0092 0.0459 0.0875
Echinococcus granulosus neuropeptide receptor 0.0015 0.0023 0.0044
Loa Loa (eye worm) nuclear hormone receptor family member nhr-31 0.0012 0.0005 0.0007
Echinococcus granulosus FTZ F1 nuclear receptor protein 0.0012 0.0005 0.0009
Plasmodium vivax histone acetyltransferase GCN5, putative 0.0046 0.0199 0.0241
Loa Loa (eye worm) hypothetical protein 0.0041 0.017 0.0287
Brugia malayi Dopamine receptor protein 2 0.0015 0.0023 0.0039
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0015 0.0023 0.0043
Loa Loa (eye worm) hypothetical protein 0.0102 0.0521 0.0882
Mycobacterium tuberculosis Probable fatty-acid-CoA ligase FadD3 (fatty-acid-CoA synthetase) (fatty-acid-CoA synthase) 0.0019 0.0044 0.0196
Leishmania major 4-coumarate:coa ligase-like protein 0.0027 0.0089 0.144
Echinococcus multilocularis serotonin receptor 0.0015 0.0023 0.0023
Onchocerca volvulus 0.0015 0.0023 0.007
Echinococcus multilocularis GPCR, family 2 0.0088 0.0439 0.0439
Mycobacterium leprae Possible lysyl-tRNA synthetase 2 LysX 0.0076 0.0371 0.7027
Loa Loa (eye worm) jmjC domain-containing protein 0.0039 0.0161 0.0271
Mycobacterium ulcerans acyl-CoA synthetase 0.0027 0.0089 0.2401
Schistosoma mansoni survival motor neuron protein 0.0056 0.0255 0.0486
Schistosoma mansoni nuclear receptor 2DBD-gamma 0.0012 0.0005 0.0008
Brugia malayi Bifunctional aminoacyl-tRNA synthetase 0.0102 0.0521 0.0881
Schistosoma mansoni opsin-like receptor 0.0015 0.0023 0.0043
Loa Loa (eye worm) hypothetical protein 0.0027 0.0089 0.0151
Plasmodium vivax calcium-dependent protein kinase, putative 0.0105 0.0534 0.0648
Brugia malayi Nuclear hormone receptor family member nhr-1 0.0012 0.0005 0.0007
Leishmania major phosphatidylinositol 3-related kinase, putative 0.0018 0.0039 0.0627
Echinococcus granulosus g-protein coupled receptor 0.0015 0.0023 0.0044
Schistosoma mansoni hypothetical protein 0.0088 0.0439 0.0836
Mycobacterium tuberculosis Lysyl-tRNA synthetase 1 LysS (lysine--tRNA ligase 1) (LysRS 1) (lysine translase) 0.0065 0.0305 0.2036
Mycobacterium ulcerans cytochrome P450 191A3 Cyp191A3 0.0014 0.0016 0.0425
Schistosoma mansoni tar DNA-binding protein 0.0066 0.0314 0.0598
Loa Loa (eye worm) hypothetical protein 0.0048 0.021 0.0354
Loa Loa (eye worm) hypothetical protein 0.0012 0.0005 0.0007
Trichomonas vaginalis conserved hypothetical protein 0.0017 0.0032 0.0117
Echinococcus multilocularis g protein linked acetylcholine receptor gar 2a 0.0015 0.0023 0.0023
Brugia malayi putative neuropeptide receptor NPR1 0.0015 0.0023 0.0039
Trypanosoma cruzi prolyl-tRNA synthetase, putative 0.0119 0.0618 1
Loa Loa (eye worm) jmjC domain-containing protein 0.0061 0.0284 0.0479
Toxoplasma gondii PHD-finger domain-containing protein 0.003 0.0104 0.0189
Echinococcus multilocularis mixed lineage leukemia protein mll 0.0018 0.004 0.004
Schistosoma mansoni hypothetical protein 0.0015 0.0023 0.0043
Echinococcus multilocularis 7TM GPCR, rhodopsin 0.0015 0.0023 0.0023
Schistosoma mansoni histone-lysine n-methyltransferase setb1 0.0062 0.0288 0.0549
Brugia malayi hypothetical protein 0.0275 0.1508 0.2551
Onchocerca volvulus 0.0015 0.0023 0.007
Schistosoma mansoni biogenic amine (octopamine/dopamine) receptor 0.0015 0.0023 0.0043
Trichomonas vaginalis threonyl-tRNA synthetase, putative 0.0019 0.0045 0.0165
Brugia malayi GTP-binding regulatory protein Gs alpha-S chain, putative 0.0092 0.0459 0.0776
Echinococcus granulosus disco interacting protein 2 0.004 0.0164 0.0312
Echinococcus multilocularis serotonin receptor 0.0015 0.0023 0.0023
Wolbachia endosymbiont of Brugia malayi threonyl-tRNA synthetase 0.0019 0.0045 0.2114
Mycobacterium tuberculosis Probable dicarboxylic acid transport integral membrane protein KgtP (dicarboxylate transporter) 0.0048 0.021 0.1362
Echinococcus granulosus 7TM GPCR rhodopsin 0.0015 0.0023 0.0044
Leishmania major hypothetical protein, conserved 0.0048 0.021 0.3384
Schistosoma mansoni cpg binding protein 0.0103 0.0522 0.0995
Loa Loa (eye worm) hypothetical protein 0.0041 0.017 0.0287
Schistosoma mansoni family S12 unassigned peptidase (S12 family) 0.0041 0.017 0.0323
Loa Loa (eye worm) hypothetical protein 0.0015 0.0023 0.0039
Schistosoma mansoni lysyl-tRNA synthetase 0.0076 0.0371 0.0707
Brugia malayi Phosphatidylinositol 3- and 4-kinase family protein 0.0025 0.0078 0.0132
Brugia malayi photoreceptor-specific nuclear receptor 0.0012 0.0005 0.0007
Trypanosoma cruzi GTP-binding nuclear protein rtb2, putative 0.0026 0.0081 0.1309
Trichomonas vaginalis sugar transporter, putative 0.0048 0.021 0.0779
Schistosoma mansoni hypothetical protein 0.0014 0.0016 0.003
Echinococcus multilocularis peptide (allatostatin:somatostatin) 0.0015 0.0023 0.0023
Plasmodium vivax proline--tRNA ligase, putative 0.0119 0.0618 0.0751
Schistosoma mansoni hypothetical protein 0.0013 0.0009 0.0017
Plasmodium falciparum lysine--tRNA ligase 0.0076 0.0371 0.045
Trypanosoma brucei Aminoacyl-tRNA editing domain containing protein, putative 0.0017 0.0032 0.051
Treponema pallidum glycyl-tRNA synthetase 0.0012 0.0001 0.002
Brugia malayi hypothetical protein 0.0015 0.0023 0.0039
Onchocerca volvulus 0.0035 0.0135 0.0485
Trichomonas vaginalis PIKK family atypical protein kinase 0.0018 0.0039 0.0145
Trypanosoma cruzi isocitrate dehydrogenase [NADP], mitochondrial precursor, putative 0.0032 0.0115 0.1857
Brugia malayi Ligand-binding domain of nuclear hormone receptor family protein 0.0012 0.0005 0.0007
Schistosoma mansoni serine/threonine protein kinase 0.0105 0.0533 0.1016
Brugia malayi Nuclear hormone receptor family member nhr-40 0.0012 0.0005 0.0007
Toxoplasma gondii YbaK/proline-tRNA ligase associated domain-containing protein 0.0017 0.0032 0.0058
Trichomonas vaginalis chromobox protein, putative 0.0013 0.0009 0.0033
Loa Loa (eye worm) hypothetical protein 0.0048 0.021 0.0354
Trichomonas vaginalis sugar transporter, putative 0.0048 0.021 0.0779
Echinococcus granulosus retinoic acid receptor rxr beta a 0.0012 0.0005 0.0009
Brugia malayi Protein cec-1. 0.0013 0.0009 0.0015
Chlamydia trachomatis histidine--tRNA ligase 0.0012 0.0001 0.0008
Mycobacterium ulcerans lipase LipD 0.0041 0.017 0.4567
Schistosoma mansoni hypothetical protein 0.0342 0.189 0.3604
Trichomonas vaginalis PIKK family atypical protein kinase 0.0018 0.0039 0.0145
Echinococcus granulosus calcium:calmodulin dependent protein kinase type 0.0105 0.0533 0.1017
Brugia malayi Importin beta-1 subunit 0.0035 0.0134 0.0226
Trypanosoma cruzi hypothetical protein, conserved 0.0017 0.0032 0.0508
Echinococcus granulosus histone acetyltransferase KAT2B 0.0153 0.0808 0.154
Brugia malayi Cytochrome P450 family protein 0.0053 0.0236 0.0399
Echinococcus granulosus g protein coupled receptor 0.0015 0.0023 0.0044
Plasmodium falciparum heterochromatin protein 1 0.0013 0.0009 0.0011
Schistosoma mansoni histamine h1 receptor 0.0015 0.0023 0.0043
Chlamydia trachomatis proline--tRNA ligase 0.0036 0.0142 0.3815
Loa Loa (eye worm) hypothetical protein 0.0022 0.0058 0.0098
Toxoplasma gondii ABC1 family protein 0.0041 0.017 0.031
Leishmania major lanosterol 14-alpha-demethylase, putative 0.0014 0.0016 0.0255
Leishmania major histidyl-tRNA synthetase, putative 0.0012 0.0001 0.0005
Brugia malayi hypothetical protein 0.0043 0.0182 0.0307
Trichomonas vaginalis Importin beta-1 subunit, putative 0.0028 0.0096 0.0357
Echinococcus granulosus FKBP12 rapamycin complex associated protein 0.0018 0.0039 0.0075
Schistosoma mansoni FTZ-F1 nuclear receptor-like protein 0.0012 0.0005 0.0008
Echinococcus multilocularis serine protein kinase ATM 0.0025 0.0078 0.0078
Schistosoma mansoni hypothetical protein 0.0372 0.2063 0.3933
Loa Loa (eye worm) hypothetical protein 0.0015 0.0023 0.0039
Schistosoma mansoni lysyl-tRNA synthetase 0.0076 0.0371 0.0707
Mycobacterium tuberculosis Fatty-acid-AMP ligase FadD30 (fatty-acid-AMP synthetase) (fatty-acid-AMP synthase) 0.002 0.005 0.024
Leishmania major target of rapamycin (TOR) kinase 2, putative 0.0018 0.0039 0.0627
Brugia malayi jmjC domain containing protein 0.0039 0.0161 0.0271
Schistosoma mansoni adenoreceptor 0.0015 0.0023 0.0043
Onchocerca volvulus 0.0015 0.0023 0.007
Echinococcus granulosus g protein linked acetylcholine receptor gar 2a 0.0015 0.0023 0.0044
Echinococcus granulosus Threonyl tRNA synthetase C 0.0019 0.0045 0.0085
Echinococcus multilocularis Chromobox protein 3 0.0013 0.0009 0.0009
Trichomonas vaginalis sugar transporter, putative 0.0048 0.021 0.0779
Echinococcus multilocularis rhodopsin orphan GPCR 0.0015 0.0023 0.0023
Loa Loa (eye worm) cytochrome P450 family protein 0.0053 0.0236 0.0399
Schistosoma mansoni alpha-1 adrenergic receptor 0.0015 0.0023 0.0043
Onchocerca volvulus 0.0015 0.0023 0.007
Toxoplasma gondii FATC domain-containing protein 0.0025 0.0078 0.0143
Loa Loa (eye worm) hypothetical protein 0.003 0.0104 0.0175
Mycobacterium tuberculosis Conserved protein 0.0041 0.017 0.1081
Trypanosoma cruzi phosphatidylinositol 3-related kinase, putative 0.0018 0.0039 0.0627
Echinococcus granulosus cadherin EGF LAG seven pass G type receptor 0.0088 0.0439 0.0836
Echinococcus granulosus hypothetical protein 0.0015 0.0023 0.0044
Leishmania major glycyl tRNA synthetase, putative 0.0012 0.0001 0.0005
Loa Loa (eye worm) hypothetical protein 0.0043 0.0182 0.0307
Entamoeba histolytica threonyl-tRNA synthetase, putative 0.0019 0.0045 0.0227
Echinococcus granulosus allatostatin A receptor 0.0015 0.0023 0.0044
Brugia malayi G protein-coupled receptor F59B2.13 0.0015 0.0023 0.0039
Echinococcus granulosus rhodopsin orphan GPCR 0.0015 0.0023 0.0044
Entamoeba histolytica DNA repair and recombination protein RAD52, putative 0.0352 0.195 1
Echinococcus granulosus neuropeptides capa receptor 0.0015 0.0023 0.0044
Echinococcus granulosus tar DNA binding protein 0.0066 0.0314 0.0599
Mycobacterium tuberculosis Possible conserved lipoprotein LpqK 0.0041 0.017 0.1081
Plasmodium vivax hypothetical protein, conserved 0.0014 0.0013 0.0015
Entamoeba histolytica protein kinase, putative 0.0105 0.0533 0.2733
Giardia lamblia DNA repair protein RAD52 0.0352 0.195 1
Entamoeba histolytica histidyl-tRNA synthetase, putative 0.0012 0.0001 0.0001
Schistosoma mansoni chromobox protein 0.0013 0.0009 0.0017
Schistosoma mansoni disco-interacting protein 2 (dip2) 0.004 0.0164 0.0311
Giardia lamblia GTP-binding nuclear protein RAN/TC4 0.0026 0.0081 0.0415
Trypanosoma cruzi histidyl-tRNA synthetase 0.0012 0.0001 0.0005
Wolbachia endosymbiont of Brugia malayi prolyl-tRNA synthetase 0.0019 0.0045 0.2114
Echinococcus granulosus peptide allatostatin:somatostatin 0.0015 0.0023 0.0044
Trypanosoma brucei glucose transporter, putative 0.0106 0.0541 0.8748
Brugia malayi glycyl-tRNA synthetase 0.0019 0.0045 0.0075
Echinococcus multilocularis rhodopsin orphan GPCR 0.0015 0.0023 0.0023
Echinococcus multilocularis diuretic hormone 44 receptor GPRdih2 0.0088 0.0439 0.0439
Trichomonas vaginalis conserved hypothetical protein 0.0045 0.019 0.0705
Loa Loa (eye worm) hypothetical protein 0.0035 0.0134 0.0226
Schistosoma mansoni loxhd1 0.0043 0.0182 0.0346
Plasmodium vivax calcium-dependent protein kinase 1, putative 0.0105 0.0534 0.0648
Echinococcus multilocularis rhodopsin orphan GPCR 0.0015 0.0023 0.0023
Toxoplasma gondii isocitrate dehydrogenase 0.0032 0.0115 0.021
Brugia malayi hypothetical protein 0.0048 0.021 0.0354
Echinococcus granulosus arachidonate 5 lipoxygenase 0.0258 0.1414 0.2696
Brugia malayi nuclear receptor NHR-88 0.0012 0.0005 0.0007
Loa Loa (eye worm) hypothetical protein 0.0015 0.0023 0.0039
Toxoplasma gondii transporter, major facilitator family protein 0.0048 0.021 0.0383
Leishmania major hypothetical protein, conserved 0.0041 0.017 0.2739
Schistosoma mansoni myosin xvIII 0.0015 0.0023 0.0043
Echinococcus granulosus histone lysine N methyltransferase MLL3 0.0022 0.0063 0.012
Loa Loa (eye worm) melatonin receptor type 1A 0.0015 0.0023 0.0039
Trichomonas vaginalis sugar transporter, putative 0.0048 0.021 0.0779
Mycobacterium ulcerans cytochrome P450 108B4 Cyp108B4 0.0014 0.0016 0.0425
Brugia malayi probable proline-trna synthetase - fission yeast, putative 0.0019 0.0045 0.0075
Schistosoma mansoni hypothetical protein 0.0558 0.3128 0.5965
Toxoplasma gondii glycyl-tRNA synthetase 0.0019 0.0045 0.0081
Echinococcus multilocularis neuropeptide s receptor 0.0015 0.0023 0.0023
Loa Loa (eye worm) hypothetical protein 0.0048 0.021 0.0354
Brugia malayi PHD-finger family protein 0.003 0.0104 0.0175
Loa Loa (eye worm) hypothetical protein 0.0041 0.017 0.0287
Plasmodium vivax hypothetical protein, conserved 0.0013 0.0009 0.0011
Trichomonas vaginalis PIKK family atypical protein kinase 0.0018 0.0039 0.0145
Loa Loa (eye worm) hypothetical protein 0.0015 0.0023 0.0039
Trichomonas vaginalis PIKK family atypical protein kinase 0.0018 0.0039 0.0145
Trypanosoma brucei glucose transporter 2A 0.0106 0.0541 0.8748
Trichomonas vaginalis D-aminoacylase, putative 0.0041 0.017 0.0631
Echinococcus multilocularis solute carrier family 22 0.0048 0.021 0.021
Plasmodium vivax acyl-CoA synthetase, putative 0.002 0.005 0.0061
Trichomonas vaginalis conserved hypothetical protein 0.0015 0.0019 0.007
Echinococcus granulosus pyroglutamylated rfamide peptide receptor 0.0015 0.0023 0.0044
Brugia malayi Tachykinin-like peptides receptor 99D 0.0015 0.0023 0.0039
Plasmodium falciparum hexose transporter 0.0342 0.189 0.2295
Trichomonas vaginalis chromobox protein, putative 0.0079 0.039 0.145
Brugia malayi steroid hormone receptor 0.0012 0.0005 0.0007
Mycobacterium tuberculosis Probable hydrolase 0.0041 0.017 0.1081
Trichomonas vaginalis conserved hypothetical protein 0.0013 0.0009 0.0033
Leishmania major cytochrome p450-like protein 0.0014 0.0016 0.0255
Onchocerca volvulus 0.0048 0.021 0.0765
Echinococcus multilocularis dro:myosuppressin receptor 0.0015 0.0023 0.0023
Leishmania major modification methylase-like protein 0.002 0.0049 0.0783
Echinococcus multilocularis FTZ F1 alpha 0.0012 0.0005 0.0005
Schistosoma mansoni lipoxygenase 0.0258 0.1414 0.2696
Onchocerca volvulus 0.0048 0.021 0.0765
Trichomonas vaginalis importin beta-1, putative 0.0028 0.0096 0.0357
Leishmania major prolyl-tRNA synthetase, putative,bifunctional aminoacyl-tRNA synthetase, putative 0.0119 0.0618 1
Entamoeba histolytica Rad52/22 family double-strand break repair protein, putative 0.01 0.0508 0.2604
Echinococcus multilocularis chromodomain helicase DNA binding protein 4 0.0017 0.003 0.003
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0015 0.0023 0.0043
Trypanosoma brucei isocitrate dehydrogenase [NADP], mitochondrial precursor, putative 0.0032 0.0115 0.1858
Brugia malayi Type III restriction enzyme, res subunit family protein 0.0013 0.0009 0.0015
Leishmania major target of rapamycin kinase (TOR) kinase 3 0.0018 0.0039 0.0627
Trichomonas vaginalis sugar transporter, putative 0.0048 0.021 0.0779
Brugia malayi Heterochromatin protein 1 0.0079 0.039 0.0658
Trypanosoma brucei aspartyl-tRNA synthetase, putative 0.0011 0 0.0002
Brugia malayi Nuclear hormone receptor family member nhr-49 0.0012 0.0005 0.0007
Entamoeba histolytica prolyl-tRNA synthetase, putative 0.0102 0.0521 0.2671
Schistosoma mansoni ran 0.0026 0.0081 0.0154
Trichomonas vaginalis myo-inositol transporter, putative 0.0048 0.021 0.0779
Loa Loa (eye worm) hypothetical protein 0.0048 0.021 0.0354
Echinococcus multilocularis growth hormone secretagogue receptor type 1 0.0015 0.0023 0.0023
Toxoplasma gondii protein kinase, putative 0.0965 0.5459 1
Echinococcus multilocularis fmrfamide receptor 0.0015 0.0023 0.0023
Trypanosoma brucei target of rapamycin kinase 3, putative 0.0018 0.0039 0.0628
Trichomonas vaginalis lysyl-tRNA synthetase, putative 0.0076 0.0371 0.1381
Echinococcus granulosus NADP dependent isocitrate dehydrogenase 0.0032 0.0115 0.022
Echinococcus multilocularis nuclear receptor 2DBD gamma 0.0012 0.0005 0.0005
Loa Loa (eye worm) hypothetical protein 0.0015 0.0023 0.0039
Echinococcus multilocularis histone lysine methyltransferase setb histone lysine methyltransferase eggless 0.0062 0.0288 0.0288
Echinococcus multilocularis Transcription factor, JmjC domain containing protein 0.0097 0.0488 0.0488
Echinococcus multilocularis neuropeptide FF receptor 2 0.0015 0.0023 0.0023
Schistosoma mansoni amine GPCR 0.0015 0.0023 0.0043
Trichomonas vaginalis cat eye syndrome critical region protein 2, cscr2, putative 0.0046 0.0199 0.0739
Schistosoma mansoni neuropeptide receptor 0.0015 0.0023 0.0043
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0015 0.0023 0.0043
Plasmodium vivax GTP-binding nuclear protein RAN/TC4, putative 0.0026 0.0081 0.0098
Loa Loa (eye worm) sugar transporter 0.0048 0.021 0.0354
Brugia malayi hypothetical protein 0.0048 0.021 0.0354
Echinococcus granulosus snurportin 1 0.0372 0.2063 0.3933
Brugia malayi Pre-SET motif family protein 0.0422 0.2352 0.398
Echinococcus granulosus GTP binding nuclear protein Ran 0.0026 0.0081 0.0155
Onchocerca volvulus 0.0048 0.021 0.0765
Brugia malayi M-phase phosphoprotein, mpp8 0.0013 0.0009 0.0015
Echinococcus multilocularis solute carrier family 22 0.0048 0.021 0.021
Brugia malayi isocitrate dehydrogenase 0.0032 0.0115 0.0194
Trichomonas vaginalis sugar transport protein, putative 0.0048 0.021 0.0779
Brugia malayi major facilitator superfamily protein 0.0048 0.021 0.0354
Echinococcus multilocularis ecdysone induced protein 78C 0.0012 0.0005 0.0005
Loa Loa (eye worm) GTP-binding regulatory protein Gs alpha-S chain 0.0092 0.0459 0.0776
Plasmodium falciparum isocitrate dehydrogenase [NADP], mitochondrial 0.0032 0.0115 0.0139
Brugia malayi Cytochrome P450 family protein 0.0014 0.0016 0.0027
Echinococcus granulosus neuropeptide s receptor 0.0015 0.0023 0.0044
Trypanosoma cruzi glycyl-tRNA synthetase, putative 0.0012 0.0001 0.0005
Trypanosoma cruzi phosphatidylinositol kinase related protein, putative 0.0025 0.0078 0.1259
Brugia malayi Dopamine receptor 0.0015 0.0023 0.0039
Schistosoma mansoni biogenic amine (dopamine) receptor 0.0015 0.0023 0.0043
Trichomonas vaginalis glucose transporter, putative 0.0048 0.021 0.0779
Echinococcus granulosus beta LACTamase domain containing family member 0.0041 0.017 0.0324
Loa Loa (eye worm) pre-SET domain-containing protein family protein 0.0422 0.2352 0.398
Echinococcus multilocularis dnaJ subfamily B 0.0927 0.5244 0.5244
Trichomonas vaginalis conserved hypothetical protein 0.0342 0.189 0.7038
Echinococcus multilocularis lipoxygenase domain containing protein 0.0043 0.0182 0.0182
Echinococcus multilocularis rhodopsin orphan GPCR 0.0015 0.0023 0.0023
Loa Loa (eye worm) nuclear hormone receptor family member nhr-40 0.0012 0.0005 0.0007
Loa Loa (eye worm) hypothetical protein 0.0076 0.0371 0.0627
Schistosoma mansoni glucose transport protein 0.0342 0.189 0.3604
Mycobacterium tuberculosis Lysyl-tRNA synthetase 2 LysX 0.0065 0.0305 0.2036
Echinococcus multilocularis geminin 0.0558 0.3128 0.3128
Loa Loa (eye worm) hypothetical protein 0.0012 0.0005 0.0007
Trichomonas vaginalis PIKK family atypical protein kinase 0.0018 0.0039 0.0145
Trichomonas vaginalis conserved hypothetical protein 0.0048 0.021 0.0779
Schistosoma mansoni hypothetical protein 0.003 0.0104 0.0197
Schistosoma mansoni NADP-specific isocitrate dehydrogenase 0.0032 0.0115 0.0219
Schistosoma mansoni hypothetical protein 0.019 0.1023 0.1951
Mycobacterium ulcerans sugar transporter 0.0048 0.021 0.5643
Echinococcus multilocularis tm gpcr rhodopsin gpcr rhodopsin superfamily 0.0015 0.0023 0.0023
Onchocerca volvulus 0.0048 0.021 0.0765
Onchocerca volvulus 0.0048 0.021 0.0765
Loa Loa (eye worm) hypothetical protein 0.0015 0.0023 0.0039
Schistosoma mansoni amine GPCR 0.0015 0.0023 0.0043
Onchocerca volvulus 0.0048 0.021 0.0765
Echinococcus multilocularis PHD finger protein rhinoceros 0.003 0.0104 0.0104
Trichomonas vaginalis conserved hypothetical protein 0.0015 0.0019 0.007
Leishmania major protein kinase, putative 0.0105 0.0533 0.8623
Trypanosoma cruzi cytochrome p450-like protein, putative 0.0014 0.0016 0.0255
Entamoeba histolytica acyl-CoA synthetase, putative 0.0027 0.0089 0.0456
Trichomonas vaginalis conserved hypothetical protein 0.0174 0.0928 0.3457
Plasmodium falciparum conserved Plasmodium protein, unknown function 0.0013 0.0009 0.0011
Trichomonas vaginalis conserved hypothetical protein 0.0015 0.0019 0.007
Trichomonas vaginalis sugar transporter, putative 0.0048 0.021 0.0779
Loa Loa (eye worm) isocitrate dehydrogenase 0.0032 0.0115 0.0194
Trichomonas vaginalis PIKK family atypical protein kinase 0.0018 0.0039 0.0145
Brugia malayi hypothetical protein 0.0015 0.0023 0.0039
Mycobacterium ulcerans cytochrome P450 189A7 Cyp189A7 0.0014 0.0016 0.0425
Onchocerca volvulus 0.0048 0.021 0.0765
Echinococcus multilocularis rhodopsin orphan GPCR 0.0015 0.0023 0.0023
Toxoplasma gondii calcium-dependent protein kinase CDPK3 0.0105 0.0534 0.0977
Echinococcus granulosus calcium:calmodulin dependent protein kinase type 1 0.0105 0.0533 0.1017
Echinococcus multilocularis thyrotropin releasing hormone receptor 0.0015 0.0023 0.0023
Toxoplasma gondii histone lysine acetyltransferase GCN5-B 0.0046 0.0199 0.0364
Trypanosoma brucei GTP-binding nuclear protein rtb2, putative 0.0026 0.0081 0.1311
Trichomonas vaginalis chromodomain-helicase-DNA-binding protein, putative 0.0028 0.0094 0.0347
Loa Loa (eye worm) hypothetical protein 0.0105 0.0533 0.0902
Trichomonas vaginalis conserved hypothetical protein 0.0106 0.0541 0.2014
Brugia malayi AKH receptor 0.0015 0.0023 0.0039
Schistosoma mansoni RAR-like nuclear receptor 0.0012 0.0005 0.0008
Trypanosoma brucei THT1 - hexose transporter, putative 0.0106 0.0541 0.8748
Trypanosoma brucei Phosphatidylinositol 3-kinase tor1 0.0018 0.0039 0.0628
Echinococcus multilocularis lysine specific demethylase 5A 0.0036 0.0139 0.0139
Onchocerca volvulus Alhambra homolog 0.003 0.0104 0.037
Plasmodium vivax hypothetical protein, conserved 0.003 0.0104 0.0125
Echinococcus multilocularis tm gpcr rhodopsin gpcr rhodopsin superfamily 0.0015 0.0023 0.0023
Entamoeba histolytica phosphatidylinositol3-kinaseTor2, putative 0.0018 0.0039 0.0199
Schistosoma mansoni sugar transporter 0.0048 0.021 0.0399
Trypanosoma brucei glucose transporter, putative 0.0106 0.0541 0.8748
Echinococcus multilocularis G protein coupled receptor 139 0.0015 0.0023 0.0023
Echinococcus multilocularis sex peptide receptor 0.0015 0.0023 0.0023
Trichomonas vaginalis PIKK family atypical protein kinase 0.0018 0.0039 0.0145
Brugia malayi SET domain containing protein 0.0017 0.003 0.005
Echinococcus granulosus hepatocyte nuclear factor 4 alpha 0.0012 0.0005 0.0009
Entamoeba histolytica acyl-CoA synthetase, putative 0.0027 0.0089 0.0456
Echinococcus multilocularis solute carrier family 22 0.0048 0.021 0.021
Trichomonas vaginalis conserved hypothetical protein 0.0013 0.0009 0.0033
Loa Loa (eye worm) doublecortin family protein 0.0043 0.0182 0.0307
Loa Loa (eye worm) hypothetical protein 0.0015 0.0023 0.0039
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0015 0.0023 0.0043
Trichomonas vaginalis sugar transporter, putative 0.0048 0.021 0.0779
Brugia malayi hypothetical protein 0.0015 0.0023 0.0039
Echinococcus granulosus histone acetyltransferase KAT2B 0.0046 0.0199 0.0379
Echinococcus multilocularis solute carrier family 2 facilitated glucose 0.0342 0.189 0.189
Loa Loa (eye worm) nuclear hormone receptor family member nhr-49 0.0012 0.0005 0.0007
Echinococcus granulosus G protein coupled receptor 139 0.0015 0.0023 0.0044
Mycobacterium tuberculosis Probable lipase LipD 0.0041 0.017 0.1081
Loa Loa (eye worm) TYRA-2 protein 0.0015 0.0023 0.0039
Echinococcus granulosus lysyl tRNA synthetase 0.0076 0.0371 0.0708
Echinococcus granulosus histidyl tRNA synthetase 0.0012 0.0001 0.0001
Schistosoma mansoni hypothetical protein 0.0056 0.0255 0.0486
Schistosoma mansoni peptide (FMRFamide/somatostatin)-like receptor 0.0015 0.0023 0.0043
Loa Loa (eye worm) hypothetical protein 0.0048 0.021 0.0354
Plasmodium falciparum conserved Plasmodium membrane protein, unknown function 0.0014 0.0013 0.0015
Echinococcus granulosus 7tm_1 domain containing protein 0.0015 0.0023 0.0044
Brugia malayi Cam kinase protein 1 0.0105 0.0533 0.0902
Echinococcus multilocularis isocitrate dehydrogenase 2 (NADP+) 0.0032 0.0115 0.0115
Mycobacterium tuberculosis Probable fatty-acid-CoA ligase FadD2 (fatty-acid-CoA synthetase) (fatty-acid-CoA synthase) 0.0027 0.0089 0.0516
Onchocerca volvulus 0.0048 0.021 0.0765
Mycobacterium ulcerans fusion of enoyl-CoA hydratase, EchA21 and lipase, LipE 0.0041 0.017 0.4567
Echinococcus multilocularis glycyl tRNA synthetase 0.0019 0.0045 0.0045
Schistosoma mansoni bromodomain-containing nuclear protein 1 brd1 0.003 0.0104 0.0197
Brugia malayi larval opioid receptor 0.0015 0.0023 0.0039
Echinococcus multilocularis solute carrier family 2 facilitated glucose 0.0342 0.189 0.189
Trichomonas vaginalis PIKK family atypical protein kinase 0.0018 0.0039 0.0145
Mycobacterium ulcerans cytochrome P450 144A4 Cyp144A4 0.0014 0.0016 0.0425
Echinococcus multilocularis chromobox protein 1 0.0079 0.039 0.039
Echinococcus granulosus calcium:calmodulin dependent protein kinase type 0.0105 0.0533 0.1017
Trichomonas vaginalis PIKK family atypical protein kinase 0.0018 0.0039 0.0145
Loa Loa (eye worm) neuropeptide F receptor 0.0015 0.0023 0.0039
Schistosoma mansoni protein kinase 0.0105 0.0533 0.1016
Echinococcus multilocularis tachykinin peptides receptor 99D 0.0015 0.0023 0.0023
Schistosoma mansoni nuclear hormone receptor 0.0012 0.0005 0.0008
Echinococcus granulosus histone lysine methyltransferase setb 0.0062 0.0288 0.055
Loa Loa (eye worm) hypothetical protein 0.0027 0.0089 0.0151
Echinococcus granulosus DNA methyltransferase 2, putative 0.002 0.0049 0.0093
Brugia malayi Nuclear hormone receptor family member nhr-19 0.0012 0.0005 0.0007
Echinococcus granulosus neuropeptide receptor A26 0.0015 0.0023 0.0044
Echinococcus multilocularis NADP dependent isocitrate dehydrogenase 0.0032 0.0115 0.0115
Trypanosoma brucei phosphatidylinositol 3-kinase, putative 0.0018 0.0039 0.0628
Trypanosoma brucei sugar transporter, putative 0.0048 0.021 0.3385
Schistosoma mansoni threonyl-tRNA synthetase 0.0012 0.0001 0.0001
Entamoeba histolytica hypothetical protein 0.0013 0.0009 0.0044
Trichomonas vaginalis sugar transporter, putative 0.0048 0.021 0.0779
Loa Loa (eye worm) CYP4Cod1 0.0014 0.0016 0.0027
Trypanosoma cruzi threonyl-tRNA synthetase, putative 0.0019 0.0045 0.0715
Mycobacterium tuberculosis Probable conserved integral membrane transport protein 0.0048 0.021 0.1362
Trypanosoma cruzi sugar transporter, putative 0.0048 0.021 0.3384
Loa Loa (eye worm) hypothetical protein 0.0041 0.017 0.0287
Toxoplasma gondii histone lysine methyltransferase SET1 0.0129 0.0676 0.1237
Loa Loa (eye worm) phosphatidylinositol 3 0.0018 0.0039 0.0066
Echinococcus multilocularis NADP dependent isocitrate dehydrogenase 0.0032 0.0115 0.0115
Schistosoma mansoni histone-lysine n-methyltransferase setb1 0.0062 0.0288 0.0549
Schistosoma mansoni neuropeptide f receptor 76f 0.0015 0.0023 0.0043
Echinococcus multilocularis chromodomain helicase DNA binding protein 1 0.0013 0.0009 0.0009
Entamoeba histolytica protein kinase, putative 0.0105 0.0533 0.2733
Echinococcus multilocularis FTZ F1 nuclear receptor protein 0.0012 0.0005 0.0005
Loa Loa (eye worm) MH2 domain-containing protein 0.0141 0.0744 0.1259
Loa Loa (eye worm) G-protein-linked acetylcholine receptor protein 2 0.0015 0.0023 0.0039
Trichomonas vaginalis PIKK family atypical protein kinase 0.0018 0.0039 0.0145
Loa Loa (eye worm) follicle stimulating hormone receptor 0.1044 0.5909 1
Brugia malayi ecdysteroid receptor 0.0012 0.0005 0.0007
Brugia malayi nuclear hormone receptor 0.0012 0.0005 0.0007
Schistosoma mansoni peptide (FMRFamide/neurokinin-3)-like receptor 0.0015 0.0023 0.0043
Schistosoma mansoni hypothetical protein 0.0015 0.0023 0.0043
Toxoplasma gondii isocitrate dehydrogenase 0.0032 0.0115 0.021
Brugia malayi Calcitonin receptor-like protein seb-1 0.0278 0.1527 0.2584
Echinococcus granulosus neuropeptide Y receptor 0.0015 0.0023 0.0044
Toxoplasma gondii target of rapamycin (TOR), putative 0.0018 0.0039 0.0071
Echinococcus granulosus lipoxygenase domain containing protein 0.0043 0.0182 0.0347
Brugia malayi hypothetical protein 0.0015 0.0023 0.0039
Brugia malayi Nuclear hormone receptor family member nhr-25 0.0012 0.0005 0.0007
Echinococcus multilocularis Jumonji, AT rich interactive domain 1B 0.0013 0.001 0.001
Echinococcus multilocularis rhodopsin orphan GPCR 0.0015 0.0023 0.0023
Entamoeba histolytica hypothetical protein 0.0025 0.0078 0.0399
Trichomonas vaginalis sugar transporter, putative 0.0048 0.021 0.0779
Loa Loa (eye worm) gonadotropin-releasing hormone receptor 2 0.0015 0.0023 0.0039
Schistosoma mansoni opsin-like receptor 0.0015 0.0023 0.0043
Echinococcus granulosus rhodopsin orphan GPCR 0.0015 0.0023 0.0044
Brugia malayi Disco-interacting protein 2 homolog 0.0039 0.0157 0.0265
Echinococcus multilocularis histidyl tRNA synthetase 0.0012 0.0001 0.0001
Echinococcus multilocularis arachidonate 5 lipoxygenase 0.0258 0.1414 0.1414
Brugia malayi Nuclear hormone receptor-like 1 0.0012 0.0005 0.0007
Loa Loa (eye worm) unidentified vitellogenin-linked transcript protein 6 0.0015 0.0023 0.0039
Echinococcus granulosus solute carrier family 2 facilitated glucose 0.0342 0.189 0.3604
Loa Loa (eye worm) G-protein coupled receptor 0.0015 0.0023 0.0039
Mycobacterium ulcerans cytochrome P450 51B1 Cyp51B1 0.0014 0.0016 0.0425
Trypanosoma cruzi hexose transporter, putative 0.0106 0.0541 0.8747
Brugia malayi Serotonin receptor 0.0015 0.0023 0.0039
Schistosoma mansoni mixed-lineage leukemia protein mll 0.0012 0.0001 0.0001
Plasmodium falciparum protein kinase 7 0.0965 0.5459 0.663
Trichomonas vaginalis PIKK family atypical protein kinase 0.0018 0.0039 0.0145
Echinococcus multilocularis pyroglutamylated rfamide peptide receptor 0.0015 0.0023 0.0023
Mycobacterium leprae PROBABLE FATTY-ACID-CoA LIGASE FADD2 (FATTY-ACID-CoA SYNTHETASE) (FATTY-ACID-CoA SYNTHASE) 0.0027 0.0089 0.145
Echinococcus granulosus g protein linked acetylcholine receptor gar 2a 0.0015 0.0023 0.0044
Schistosoma mansoni neuropeptide F-like receptor 0.0015 0.0023 0.0043
Trypanosoma brucei histidyl-tRNA synthetase 0.0012 0.0001 0.0006
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0015 0.0023 0.0043
Mycobacterium ulcerans cytochrome P450 124A1, Cyp124A1 0.0014 0.0016 0.0425
Onchocerca volvulus 0.0048 0.021 0.0765
Trichomonas vaginalis chromobox protein, putative 0.0079 0.039 0.145
Schistosoma mansoni sugar transporter 0.0048 0.021 0.0399
Echinococcus granulosus chromobox protein 1 0.0079 0.039 0.0743
Loa Loa (eye worm) hypothetical protein 0.0048 0.021 0.0354
Loa Loa (eye worm) hypothetical protein 0.0048 0.021 0.0354
Onchocerca volvulus Heterochromatin protein 1 homolog 0.0048 0.0209 0.0763
Loa Loa (eye worm) nuclear hormone receptor family member nhr-14 0.0012 0.0005 0.0007
Brugia malayi Isocitrate dehydrogenase 0.0032 0.0115 0.0194
Echinococcus granulosus Chromo domain 0.0013 0.0009 0.0017
Loa Loa (eye worm) hypothetical protein 0.0015 0.0023 0.0039
Trypanosoma brucei phosphatidylinositol 4-kinase, putative 0.0018 0.0039 0.0628
Loa Loa (eye worm) hypothetical protein 0.0015 0.0023 0.0039
Plasmodium vivax glycine--tRNA ligase, putative 0.0019 0.0045 0.0054
Mycobacterium ulcerans acyl-CoA synthetase 0.0027 0.0089 0.2401
Giardia lamblia Glycyl-tRNA synthetase 0.0019 0.0045 0.0227
Loa Loa (eye worm) transcription factor SMAD2 0.0141 0.0744 0.1259
Brugia malayi Nuclear hormone receptor family member nhr-14 0.0012 0.0005 0.0007
Entamoeba histolytica acetyltransferase, GNAT family 0.0042 0.0177 0.0905
Trypanosoma brucei importin beta-1 subunit, putative 0.0035 0.0134 0.2162
Giardia lamblia PHD finger protein 15 0.003 0.0104 0.053
Echinococcus multilocularis calcium:calmodulin dependent protein kinase type 0.0105 0.0533 0.0533
Trichomonas vaginalis sugar transporter, putative 0.0048 0.021 0.0779
Echinococcus multilocularis histone lysine N methyltransferase MLL3 0.0022 0.0063 0.0063
Echinococcus multilocularis neuropeptide receptor 0.0015 0.0023 0.0023
Trypanosoma brucei aspartyl-tRNA synthetase, putative 0.0011 0 0.0002
Trichomonas vaginalis penicillin-binding protein, putative 0.0041 0.017 0.0631
Loa Loa (eye worm) hypothetical protein 0.0048 0.021 0.0354
Schistosoma mansoni nuclear hormone receptor nor-1/nor-2 0.0012 0.0005 0.0008
Loa Loa (eye worm) glycyl-tRNA synthetase 0.0019 0.0045 0.0075
Loa Loa (eye worm) hypothetical protein 0.0051 0.0224 0.0379
Loa Loa (eye worm) hypothetical protein 0.0015 0.0023 0.0039
Brugia malayi Latrophilin receptor protein 2 0.0088 0.0439 0.0741
Schistosoma mansoni polycystin 1-related 0.0043 0.0182 0.0346
Brugia malayi AMP-binding enzyme family protein 0.0027 0.0089 0.0151
Echinococcus multilocularis Polycystic kidney disease protein 0.0043 0.0182 0.0182
Schistosoma mansoni thyrotropin-releasing hormone receptor 0.0015 0.0023 0.0043
Echinococcus multilocularis neuropeptides capa receptor 0.0015 0.0023 0.0023
Loa Loa (eye worm) hypothetical protein 0.0012 0.0005 0.0007
Trypanosoma cruzi hexose transporter, putative 0.0106 0.0541 0.8747
Trypanosoma brucei ULK family serine/threonine-protein kinase, putative 0.0013 0.001 0.0152
Loa Loa (eye worm) hypothetical protein 0.0015 0.0023 0.0039
Brugia malayi G-protein-linked acetylcholine receptor protein 2, putative 0.0015 0.0023 0.0039
Loa Loa (eye worm) CHromoDomain protein family member 0.0017 0.003 0.0051
Echinococcus multilocularis g-protein coupled receptor 0.0015 0.0023 0.0023
Echinococcus granulosus PHD finger protein rhinoceros 0.003 0.0104 0.0198
Schistosoma mansoni Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) 0.0092 0.0459 0.0875
Trichomonas vaginalis hypothetical protein 0.0013 0.0009 0.0033
Mycobacterium ulcerans cytochrome p450 150 cyp150 0.0014 0.0016 0.0425
Echinococcus granulosus rhodopsin orphan GPCR 0.0015 0.0023 0.0044
Giardia lamblia Lysyl-tRNA synthetase 0.0076 0.0371 0.1901
Brugia malayi acetyltransferase, GNAT family protein 0.0157 0.0833 0.1409
Loa Loa (eye worm) hypothetical protein 0.0027 0.0089 0.0151
Loa Loa (eye worm) hypothetical protein 0.0015 0.0023 0.0039
Echinococcus multilocularis 0.0014 0.0016 0.0016
Loa Loa (eye worm) hypothetical protein 0.0088 0.0439 0.0742
Schistosoma mansoni neuropeptide receptor 0.0015 0.0023 0.0043
Schistosoma mansoni hypothetical protein 0.0088 0.0439 0.0836
Echinococcus multilocularis calcium:calmodulin dependent protein kinase type 0.0105 0.0533 0.0533
Schistosoma mansoni hypothetical protein 0.0015 0.0023 0.0043
Echinococcus granulosus alpha 1A adrenergic receptor 0.0015 0.0023 0.0044
Trichomonas vaginalis PIKK family atypical protein kinase 0.0025 0.0078 0.029
Echinococcus multilocularis General substrate transporter 0.0294 0.1615 0.1615
Giardia lamblia Histone acetyltransferase GCN5 0.0042 0.0177 0.0905
Onchocerca volvulus 0.0048 0.021 0.0765
Trichomonas vaginalis CAMK family protein kinase 0.0105 0.0533 0.1985
Onchocerca volvulus 0.0075 0.0363 0.1337
Trichomonas vaginalis PIKK family atypical protein kinase 0.0018 0.0039 0.0145
Echinococcus granulosus serine protein kinase ATM 0.0025 0.0078 0.0149
Brugia malayi hypothetical protein 0.0015 0.0023 0.0039
Loa Loa (eye worm) nuclear hormone receptor family member nhr-41 0.0012 0.0005 0.0007
Plasmodium vivax calcium-dependent protein kinase 3, putative 0.0105 0.0534 0.0648
Echinococcus granulosus fmrfamide receptor 0.0015 0.0023 0.0044
Schistosoma mansoni amine GPCR 0.0015 0.0023 0.0043
Echinococcus granulosus Transcription factor JmjC domain containing protein 0.0097 0.0488 0.0931
Echinococcus multilocularis rhodopsin orphan GPCR 0.0015 0.0023 0.0023
Schistosoma mansoni histidyl-tRNA synthetase 0.0012 0.0001 0.0001
Trichomonas vaginalis lysyl-tRNA synthetase, putative 0.0067 0.0317 0.1181
Onchocerca volvulus Heterochromatin protein 1 homolog 0.0045 0.019 0.0691
Brugia malayi Major Facilitator Superfamily protein 0.0048 0.021 0.0354
Echinococcus granulosus tumor protein p63 0.0366 0.2029 0.3869
Brugia malayi AMP-binding enzyme family protein 0.0027 0.0089 0.0151
Wolbachia endosymbiont of Brugia malayi histidyl-tRNA synthetase 0.0012 0.0001 0.0014
Trichomonas vaginalis chromobox protein, putative 0.0048 0.0209 0.0777
Loa Loa (eye worm) hypothetical protein 0.0015 0.0023 0.0039
Plasmodium falciparum proline--tRNA ligase 0.0119 0.0618 0.0751
Giardia lamblia GTOR 0.0018 0.0039 0.0199
Trichomonas vaginalis interferon-induced, double-stranded RNA-activated protein kinase, putative 0.0012 0.0001 0.0001
Trypanosoma cruzi target of rapamycin kinase 3 0.0018 0.0039 0.0627
Schistosoma mansoni tar DNA-binding protein 0.0066 0.0314 0.0598
Loa Loa (eye worm) hypothetical protein 0.0039 0.0157 0.0266
Trichomonas vaginalis PIKK family atypical protein kinase 0.0018 0.0039 0.0145
Loa Loa (eye worm) nuclear Hormone Receptor family member 0.0012 0.0005 0.0007
Trichomonas vaginalis sugar transporter, putative 0.0048 0.021 0.0779
Echinococcus multilocularis neuropeptide receptor 0.0015 0.0023 0.0023
Plasmodium vivax mitogen-activated protein kinase 2, putative 0.0552 0.3094 0.3758
Echinococcus granulosus guanine nucleotide binding protein Gs subunit 0.0092 0.0459 0.0875
Echinococcus multilocularis lipoxygenase domain containing protein 0.0043 0.0182 0.0182
Schistosoma mansoni photoreceptor-specific nuclear receptor related 0.0012 0.0005 0.0008
Trichomonas vaginalis prolyl-tRNA synthetase, putative 0.0102 0.0521 0.194
Trichomonas vaginalis conserved hypothetical protein 0.0048 0.021 0.0779
Toxoplasma gondii lysine-tRNA ligase 0.0076 0.0371 0.0679
Mycobacterium ulcerans lysyl-tRNA synthetase 0.0076 0.0371 1
Mycobacterium tuberculosis Probable esterase/lipase LipP 0.0041 0.017 0.1081
Echinococcus multilocularis calcium:calmodulin dependent protein kinase type 0.0105 0.0533 0.0533
Loa Loa (eye worm) hypothetical protein 0.0015 0.0023 0.0039
Trichomonas vaginalis PIKK family atypical protein kinase 0.0018 0.0039 0.0145
Loa Loa (eye worm) hypothetical protein 0.0015 0.0023 0.0039
Schistosoma mansoni peptide (allatostatin)-like receptor 0.0015 0.0023 0.0043
Trichomonas vaginalis sugar transporter, putative 0.0048 0.021 0.0779
Trichomonas vaginalis sugar transporter, putative 0.0048 0.021 0.0779
Onchocerca volvulus 0.0041 0.017 0.0616
Echinococcus multilocularis solute carrier family 2, facilitated glucose 0.0342 0.189 0.189
Plasmodium vivax DNA (cytosine-5)-methyltransferase, putative 0.002 0.0049 0.0059
Onchocerca volvulus 0.0039 0.0157 0.057
Loa Loa (eye worm) hypothetical protein 0.0015 0.0023 0.0039
Echinococcus multilocularis tar DNA binding protein 0.0066 0.0314 0.0314
Brugia malayi cytochrome P450 0.0014 0.0016 0.0027
Plasmodium vivax multidomain scavenger receptor, putative 0.0043 0.0182 0.022
Echinococcus granulosus guanine nucleotide binding protein Gs subunit 0.0092 0.0459 0.0875
Mycobacterium leprae Probable threonyl-tRNA synthetase ThrS (threonine-tRNA synthetase) (ThrRS) (Threonine-tRNA ligase) 0.0019 0.0045 0.0563
Echinococcus multilocularis chromobox protein 2 0.0013 0.0009 0.0009
Schistosoma mansoni ran 0.0026 0.0081 0.0154
Echinococcus granulosus solute carrier family 22 0.0048 0.021 0.04
Leishmania major cytochrome p450-like protein 0.0014 0.0016 0.0255
Echinococcus multilocularis G protein coupled 5 hydroxytryptamine receptor 0.0015 0.0023 0.0023
Trypanosoma brucei lysyl-tRNA synthetase, putative 0.0011 0 0.0002
Trichomonas vaginalis sugar transporter, putative 0.0048 0.021 0.0779
Giardia lamblia Prolyl-tRNA synthetase 0.0102 0.0521 0.2671
Trichomonas vaginalis sugar transporter, putative 0.0048 0.021 0.0779
Echinococcus granulosus nuclear receptor 2DBD gamma 0.0012 0.0005 0.0009
Trichomonas vaginalis sugar transporter, putative 0.0048 0.021 0.0779
Trichomonas vaginalis sugar transporter, putative 0.0048 0.021 0.0779
Trypanosoma brucei glucose transporter, putative 0.0106 0.0541 0.8748
Loa Loa (eye worm) hypothetical protein 0.0015 0.0023 0.0039
Plasmodium vivax hexose transporter 0.0342 0.189 0.2295
Echinococcus granulosus asparaginyl tRNA synthetase, cytoplasmic 0.0011 0 0.0001
Echinococcus granulosus somatostatin receptor 0.0015 0.0023 0.0044
Onchocerca volvulus 0.0015 0.0023 0.007
Brugia malayi TAR-binding protein 0.0066 0.0314 0.0531
Toxoplasma gondii facilitative glucose transporter GT1 0.0342 0.189 0.3462
Schistosoma mansoni biogenic amine receptor 0.0015 0.0023 0.0043
Plasmodium falciparum calcium-dependent protein kinase 1 0.0105 0.0534 0.0648
Trypanosoma brucei hypothetical protein, conserved 0.0041 0.017 0.274
Trypanosoma cruzi glycyl-tRNA synthetase, putative 0.0012 0.0001 0.0005
Trypanosoma brucei THT1 - hexose transporter, putative 0.0106 0.0541 0.8748
Mycobacterium ulcerans fusion protein of transposase for IS2606 and sialic acid-transport integral membrane protein NanT 0.0048 0.021 0.5643
Brugia malayi Phosphatidylinositol 3- and 4-kinase family protein 0.0018 0.0039 0.0066
Plasmodium falciparum DNA (cytosine-5)-methyltransferase 0.002 0.0049 0.0059
Entamoeba histolytica glycyl-tRNA synthetase, putative 0.0019 0.0045 0.0227
Schistosoma mansoni DNA (cytosine-5)-methyltransferase 0.002 0.0049 0.0092
Brugia malayi hypothetical protein 0.0015 0.0023 0.0039
Echinococcus granulosus tm gpcr rhodopsin 0.0015 0.0023 0.0044
Loa Loa (eye worm) hypothetical protein 0.0015 0.0023 0.0039
Brugia malayi hypothetical protein 0.0015 0.0023 0.0039
Echinococcus multilocularis solute carrier family 2 facilitated glucose 0.0342 0.189 0.189
Mycobacterium leprae conserved hypothetical protein 0.0041 0.017 0.304
Loa Loa (eye worm) cytochrome P450 0.0014 0.0016 0.0027
Echinococcus granulosus mixed lineage leukemia protein mll 0.0018 0.004 0.0076
Echinococcus granulosus dnaJ subfamily B 0.0927 0.5244 1
Trichomonas vaginalis sugar transporter, putative 0.0048 0.021 0.0779
Trypanosoma cruzi hexose transporter, putative 0.0058 0.0266 0.4299
Trypanosoma cruzi Phosphatidylinositol 3-kinase tor2 0.0018 0.0039 0.0627
Echinococcus granulosus solute carrier family 2 facilitated glucose 0.0342 0.189 0.3604
Trichomonas vaginalis conserved hypothetical protein 0.0032 0.0115 0.0428
Loa Loa (eye worm) hypothetical protein 0.0015 0.0023 0.0039
Brugia malayi Melatonin receptor type 1A 0.0015 0.0023 0.0039
Trichomonas vaginalis Heterochromatin protein, putative 0.0013 0.0009 0.0033
Plasmodium falciparum calcium-dependent protein kinase 2 0.0105 0.0534 0.0648
Loa Loa (eye worm) hypothetical protein 0.0013 0.0009 0.0015
Leishmania major GTP-binding protein, putative 0.0026 0.0081 0.1309
Plasmodium vivax hypothetical protein, conserved 0.0013 0.0009 0.0011
Schistosoma mansoni lipoxygenase 0.0181 0.0969 0.1847
Plasmodium falciparum importin beta, putative 0.0035 0.0134 0.0162
Schistosoma mansoni rab6-interacting 0.0043 0.0182 0.0346
Schistosoma mansoni gcn5proteinral control of amino-acid synthesis 5-like 2 gcnl2 0.0157 0.0833 0.1588
Schistosoma mansoni histone-lysine n-methyltransferase suv9 0.0075 0.0363 0.0691
Schistosoma mansoni protein kinase 0.0105 0.0533 0.1016
Mycobacterium tuberculosis Probable esterase LipL 0.0041 0.017 0.1081
Leishmania major lysyl-tRNA synthetase, putative 0.0076 0.0371 0.5997
Schistosoma mansoni peptide (allatostatin/somatostatin)-like receptor 0.0015 0.0023 0.0043
Treponema pallidum prolyl-tRNA synthetase 0.0036 0.0142 1
Loa Loa (eye worm) hypothetical protein 0.0012 0.0005 0.0007
Loa Loa (eye worm) hypothetical protein 0.0013 0.0009 0.0015
Brugia malayi MH2 domain containing protein 0.0141 0.0744 0.1259
Loa Loa (eye worm) PHD-finger family protein 0.003 0.0104 0.0175
Schistosoma mansoni rab6-interacting 0.0043 0.0182 0.0346
Echinococcus granulosus solute carrier family 22 0.0048 0.021 0.04
Trichomonas vaginalis sugar transporter, putative 0.0048 0.021 0.0779
Entamoeba histolytica hypothetical protein 0.0076 0.0371 0.1901
Mycobacterium ulcerans cytochrome P450 142A3 Cyp142A3 0.0014 0.0016 0.0425
Schistosoma mansoni ataxia telangiectasia mutated (atm)-related 0.0018 0.0039 0.0074
Loa Loa (eye worm) hypothetical protein 0.002 0.005 0.0085
Loa Loa (eye worm) hypothetical protein 0.0015 0.0023 0.0039
Echinococcus multilocularis nuclear receptor 2DBD gamma 0.0012 0.0005 0.0005
Loa Loa (eye worm) hypothetical protein 0.0048 0.021 0.0354
Mycobacterium ulcerans fatty-acid-CoA ligase 0.0027 0.0089 0.2401
Loa Loa (eye worm) hypothetical protein 0.0013 0.0009 0.0015
Loa Loa (eye worm) histidyl-tRNA synthetase 0.0012 0.0001 0.0001
Trichomonas vaginalis sugar transporter, putative 0.0106 0.0541 0.2014
Loa Loa (eye worm) bifunctional aminoacyl-tRNA synthetase 0.0042 0.0175 0.0296
Brugia malayi hypothetical protein 0.0048 0.021 0.0354
Mycobacterium ulcerans cytochrome P450 187A4 Cyp187A4 0.0014 0.0016 0.0425
Brugia malayi G-protein coupled receptor 0.0015 0.0023 0.0039
Schistosoma mansoni chromobox protein 0.0013 0.0009 0.0017
Brugia malayi RE15519p 0.0015 0.0023 0.0039
Loa Loa (eye worm) histone methyltransferase 0.0022 0.0063 0.0106
Onchocerca volvulus 0.0041 0.017 0.0616
Leishmania major prolyl-tRNA synthetase, putative,bifunctional aminoacyl-tRNA synthetase, putative 0.0119 0.0618 1
Trichomonas vaginalis set domain proteins, putative 0.048 0.2685 1
Onchocerca volvulus 0.0048 0.021 0.0765
Schistosoma mansoni nuclear transcription factor X-box binding 1 (nfx1) 0.0048 0.021 0.0399
Schistosoma mansoni biogenic amine receptor 0.0015 0.0023 0.0043
Brugia malayi Nuclear hormone receptor family member nhr-41 0.0012 0.0005 0.0007
Trichomonas vaginalis PIKK family atypical protein kinase 0.0018 0.0039 0.0145
Echinococcus multilocularis disco interacting protein 2 0.004 0.0164 0.0164
Toxoplasma gondii hypothetical protein 0.0085 0.0424 0.0776
Loa Loa (eye worm) beta-LACTamase domain containing family member 0.0041 0.017 0.0287
Schistosoma mansoni thyroid hormone receptor 0.0012 0.0005 0.0008
Echinococcus granulosus peregrin 0.0033 0.0126 0.024
Schistosoma mansoni biogenic amine (dopamine) receptor 0.0015 0.0023 0.0043
Trypanosoma brucei glucose transporter, putative 0.0106 0.0541 0.8748
Trichomonas vaginalis conserved hypothetical protein 0.0048 0.021 0.0779
Entamoeba histolytica chromodomain-helicase-DNA-binding protein, putative 0.0013 0.0009 0.0044
Brugia malayi Voltage-gated calcium channel, T-type, alpha subunit. C. elegans cca-1 ortholog 0.0178 0.0956 0.1618
Loa Loa (eye worm) hypothetical protein 0.0062 0.0288 0.0488
Echinococcus granulosus asparaginyl tRNA synthetase cytoplasmic 0.0011 0 0.0001
Loa Loa (eye worm) CXXC zinc finger family protein 0.0099 0.0501 0.0847
Schistosoma mansoni histone-lysine n-methyltransferase setb1 0.0062 0.0288 0.0549
Schistosoma mansoni glucose transport protein 0.0342 0.189 0.3604
Loa Loa (eye worm) hypothetical protein 0.0015 0.0023 0.0039
Plasmodium vivax calcium-dependent protein kinase 4, putative 0.0105 0.0534 0.0648
Loa Loa (eye worm) hypothetical protein 0.0012 0.0005 0.0007
Echinococcus granulosus biogenic amine 5HT receptor 0.0015 0.0023 0.0044
Mycobacterium ulcerans prolyl-tRNA synthetase 0.0036 0.0142 0.3815
Trypanosoma cruzi Lanosterol 14-alpha demethylase 0.0014 0.0016 0.0255
Brugia malayi beta-lactamase family protein 0.0041 0.017 0.0286
Mycobacterium ulcerans cytochrome P450 123A3 Cyp123A3 0.0014 0.0016 0.0425
Echinococcus granulosus solute carrier family 22 0.0048 0.021 0.04
Trichomonas vaginalis sugar transporter, putative 0.0048 0.021 0.0779
Trichomonas vaginalis PIKK family atypical protein kinase 0.0018 0.0039 0.0145
Plasmodium falciparum calcium-dependent protein kinase 3 0.0105 0.0534 0.0648
Echinococcus granulosus Nuclear hormone receptor family member nhr 41 0.0012 0.0005 0.0009
Mycobacterium ulcerans cytochrome P450 187A5 Cyp187A5 0.0014 0.0016 0.0425
Loa Loa (eye worm) hypothetical protein 0.0013 0.0011 0.0018
Leishmania major hypothetical protein, conserved 0.0017 0.0032 0.0508
Echinococcus multilocularis gcn5proteinral control of amino acid synthesis 0.0157 0.0833 0.0833
Trichomonas vaginalis conserved hypothetical protein 0.0013 0.0009 0.0033
Loa Loa (eye worm) sugar transporter 0.0342 0.189 0.3198
Mycobacterium ulcerans cytochrome P450 143A4 Cyp143A4 0.0014 0.0016 0.0425
Trichomonas vaginalis sugar transporter, putative 0.0048 0.021 0.0779
Schistosoma mansoni cytochrome P450 0.0014 0.0016 0.003
Echinococcus multilocularis snurportin 1 0.0372 0.2063 0.2063
Loa Loa (eye worm) 5-hydroxytryptamine 2C receptor 0.0015 0.0023 0.0039
Loa Loa (eye worm) steroid hormone receptor 0.0012 0.0005 0.0007
Echinococcus granulosus FTZ F1 alpha 0.0012 0.0005 0.0009
Toxoplasma gondii DNA methyltransferase 2, putative 0.002 0.0049 0.0089
Echinococcus granulosus growth hormone secretagogue receptor type 1 0.0015 0.0023 0.0044
Brugia malayi Ligand-binding domain of nuclear hormone receptor family protein 0.0012 0.0005 0.0007
Trypanosoma brucei asparaginyl-tRNA synthetase, putative 0.0011 0 0.0002
Loa Loa (eye worm) hypothetical protein 0.0278 0.1527 0.2584
Brugia malayi beta-lactamase family protein 0.0041 0.017 0.0286
Schistosoma mansoni coup transcription factor 0.0012 0.0005 0.0008
Mycobacterium ulcerans lysyl-tRNA synthetase 0.0076 0.0371 1
Trichomonas vaginalis sugar transporter, putative 0.0048 0.021 0.0779
Entamoeba histolytica hypothetical protein 0.01 0.0508 0.2604
Brugia malayi CXXC zinc finger family protein 0.0099 0.0501 0.0847
Entamoeba histolytica DNA (cytosine-5)-methyltransferase, putative 0.002 0.0049 0.0248
Schistosoma mansoni Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) 0.0092 0.0459 0.0875
Loa Loa (eye worm) beta-lactamase 0.0041 0.017 0.0287
Plasmodium falciparum major facilitator superfamily domain-containing protein, putative 0.0048 0.021 0.0254
Schistosoma mansoni importin beta-1 0.0035 0.0134 0.0255
Echinococcus granulosus sex peptide receptor 0.0015 0.0023 0.0044
Mycobacterium tuberculosis Probable fatty-acid-CoA ligase FadD7 (fatty-acid-CoA synthetase) (fatty-acid-CoA synthase) 0.0019 0.0044 0.0196
Trichomonas vaginalis conserved hypothetical protein 0.0015 0.0019 0.007
Schistosoma mansoni retinoid-x-receptor (RXR) 0.0012 0.0005 0.0008
Schistosoma mansoni histidyl-tRNA synthetase 0.0012 0.0001 0.0001
Echinococcus multilocularis survival motor neuron protein 1 0.0275 0.1508 0.1508
Brugia malayi RNA recognition motif domain containing protein 0.0066 0.0314 0.0531
Mycobacterium tuberculosis Probable conserved lipoprotein 0.0041 0.017 0.1081
Leishmania major hypothetical protein, conserved 0.0017 0.0032 0.0508
Trichomonas vaginalis chromobox protein, putative 0.0013 0.0009 0.0033
Trichomonas vaginalis conserved hypothetical protein 0.0015 0.0019 0.007
Loa Loa (eye worm) hypothetical protein 0.0013 0.0009 0.0015
Echinococcus granulosus ecdysone induced protein 78C 0.0012 0.0005 0.0009
Trichomonas vaginalis helicase, putative 0.0015 0.0019 0.007
Onchocerca volvulus 0.048 0.2685 1
Mycobacterium ulcerans cytochrome P450 125A7 Cyp125A7 0.0014 0.0016 0.0425
Trichomonas vaginalis sugar transporter, putative 0.0048 0.021 0.0779
Trypanosoma cruzi phosphatidylinositol kinase related protein, putative 0.0022 0.0058 0.0933
Trichomonas vaginalis ran, putative 0.0026 0.0081 0.0302
Schistosoma mansoni thyroid hormone receptor 0.0012 0.0005 0.0008
Loa Loa (eye worm) cytochrome P450 family protein 0.0014 0.0016 0.0027
Trichomonas vaginalis chromodomain-helicase-DNA-binding protein, putative 0.0028 0.0094 0.0347
Echinococcus granulosus solute carrier family 2 facilitated glucose 0.0342 0.189 0.3604
Entamoeba histolytica chromodomain-helicase-DNA-binding protein, putative 0.0013 0.0009 0.0044
Brugia malayi Unidentified vitellogenin-linked transcript protein 6, putative 0.0015 0.0023 0.0039
Mycobacterium ulcerans cytochrome P450 150A6 Cyp150A6 0.0014 0.0016 0.0425
Onchocerca volvulus 0.0048 0.021 0.0765
Brugia malayi Nuclear hormone receptor family member nhr-25 0.0012 0.0005 0.0007
Mycobacterium ulcerans long-chain-fatty-acid-CoA ligase 0.0027 0.0089 0.2401
Leishmania major glucose transporter, lmgt1 0.0106 0.0541 0.8747
Wolbachia endosymbiont of Brugia malayi major facilitator superfamily permease 0.0048 0.021 1
Brugia malayi SET domain containing protein 0.0012 0.0002 0.0003
Trichomonas vaginalis conserved hypothetical protein 0.0017 0.0032 0.0117
Brugia malayi G protein-coupled receptor 0.0015 0.0023 0.0039
Loa Loa (eye worm) hypothetical protein 0.0015 0.0023 0.0039
Echinococcus granulosus G protein coupled 5 hydroxytryptamine receptor 0.0015 0.0023 0.0044
Trypanosoma cruzi Lanosterol 14-alpha demethylase 0.0014 0.0016 0.0255
Echinococcus granulosus biogenic amine 5HT receptor 0.0015 0.0023 0.0044
Echinococcus multilocularis COUP TF:Svp nuclear hormone receptor 0.0012 0.0005 0.0005
Brugia malayi Major Facilitator Superfamily protein 0.0048 0.021 0.0354
Echinococcus multilocularis FKBP12 rapamycin complex associated protein 0.0018 0.0039 0.0039
Trypanosoma brucei glycyl-tRNA synthetase, putative 0.0019 0.0045 0.0717
Brugia malayi Sugar transporter family protein 0.0342 0.189 0.3198
Brugia malayi Nuclear hormone receptor family member nhr-3 0.0012 0.0005 0.0007
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0015 0.0023 0.0043
Echinococcus multilocularis tumor protein p63 0.0366 0.2029 0.2029
Trichomonas vaginalis chromodomain helicase DNA binding protein, putative 0.0028 0.0094 0.0347
Onchocerca volvulus 0.0013 0.0009 0.0017
Mycobacterium leprae Probable prolyl tRNA synthetase ProS 0.0102 0.0521 1
Trichomonas vaginalis sugar transporter, putative 0.0048 0.021 0.0779
Echinococcus multilocularis NADP dependent isocitrate dehydrogenase 0.0032 0.0115 0.0115
Echinococcus multilocularis guanine nucleotide binding protein G(s) subunit 0.0092 0.0459 0.0459
Schistosoma mansoni glutamyl-tRNA synthetase cytoplasmic (glutamate--tRNA ligase) (glurs) 0.0102 0.0521 0.0993
Schistosoma mansoni biogenic amine (dopamine) receptor 0.0015 0.0023 0.0043
Toxoplasma gondii calcium-dependent protein kinase CDPK2B 0.0105 0.0534 0.0977
Trichomonas vaginalis PIKK family atypical protein kinase 0.0018 0.0039 0.0145
Echinococcus granulosus rhodopsin orphan GPCR 0.0015 0.0023 0.0044
Echinococcus multilocularis calcium:calmodulin dependent protein kinase type 0.0105 0.0533 0.0533
Loa Loa (eye worm) hypothetical protein 0.0012 0.0005 0.0007
Brugia malayi G-protein coupled receptor 0.0015 0.0023 0.0039
Mycobacterium ulcerans integral membrane transport protein 0.0048 0.021 0.5643
Loa Loa (eye worm) hypothetical protein 0.0015 0.0023 0.0039
Trypanosoma brucei phosphatidylinositol kinase related protein, putative 0.0025 0.0078 0.126
Trypanosoma cruzi isocitrate dehydrogenase, putative 0.0032 0.0115 0.1857
Trichomonas vaginalis sugar transporter, putative 0.0048 0.021 0.0779
Toxoplasma gondii 'chromo' (CHRromatin Organization MOdifier) domain-containing protein 0.0013 0.0009 0.0016
Schistosoma mansoni phosphatidylinositol 3-and 4-kinase 0.0018 0.0039 0.0074
Loa Loa (eye worm) phosphatidylinositol 3 0.0018 0.0039 0.0066
Brugia malayi jmjC domain containing protein 0.0097 0.0488 0.0826
Trichomonas vaginalis PIKK family atypical protein kinase 0.0018 0.0039 0.0145
Trichomonas vaginalis chromodomain helicase DNA binding protein, putative 0.002 0.0048 0.0178
Echinococcus multilocularis beta LACTamase domain containing family member 0.0041 0.017 0.017
Echinococcus multilocularis isocitrate dehydrogenase 0.0032 0.0115 0.0115
Trichomonas vaginalis conserved hypothetical protein 0.0013 0.0009 0.0033
Echinococcus granulosus solute carrier family 2 facilitated glucose 0.0342 0.189 0.3604
Loa Loa (eye worm) hypothetical protein 0.0035 0.0135 0.0227
Mycobacterium leprae Probable lysyl-tRNA synthase LysS (lysine--tRNA ligase 1) (LysRS 1) (lysine translase) 0.0065 0.0305 0.5724
Loa Loa (eye worm) threonyl-tRNA synthetase 0.0019 0.0045 0.0075
Trichomonas vaginalis conserved hypothetical protein 0.0013 0.0009 0.0033
Brugia malayi follicle stimulating hormone receptor 0.1044 0.5909 1
Trichomonas vaginalis conserved hypothetical protein 0.0013 0.0009 0.0033
Leishmania major glucose transporter, lmgt3 0.0106 0.0541 0.8747
Loa Loa (eye worm) latrophilin receptor protein 2 0.0088 0.0439 0.0742
Trichomonas vaginalis PIKK family atypical protein kinase 0.0018 0.0039 0.0145
Brugia malayi major facilitator superfamily protein 0.0048 0.021 0.0354
Brugia malayi AMP-binding enzyme family protein 0.0027 0.0089 0.0151
Trypanosoma cruzi prolyl-tRNA synthetase, putative 0.0119 0.0618 1
Trichomonas vaginalis PIKK family atypical protein kinase 0.0018 0.0039 0.0145
Loa Loa (eye worm) hypothetical protein 0.0015 0.0023 0.0039
Schistosoma mansoni neuropeptide F-like receptor 0.0015 0.0023 0.0043
Loa Loa (eye worm) hypothetical protein 0.0013 0.0009 0.0015
Mycobacterium ulcerans long-chain-fatty-acid--CoA ligase 0.0027 0.0089 0.2401
Echinococcus multilocularis neuropeptides capa receptor 0.0015 0.0023 0.0023
Mycobacterium ulcerans fatty-acid-CoA ligase 0.002 0.005 0.1346
Onchocerca volvulus 0.0015 0.0023 0.007
Trypanosoma cruzi cytochrome P450, putative 0.0014 0.0016 0.0255
Brugia malayi Valyl-tRNA synthetase 0.0013 0.0009 0.0015
Onchocerca volvulus 0.0048 0.021 0.0765
Trichomonas vaginalis chromodomain helicase DNA binding protein, putative 0.0028 0.0094 0.0347
Trichomonas vaginalis sugar transporter, putative 0.0106 0.0541 0.2014
Trichomonas vaginalis sugar transporter, putative 0.0106 0.0541 0.2014
Leishmania major glucose transporter/membrane transporter D2, putative 0.0106 0.0541 0.8747
Toxoplasma gondii sugar transporter ST2 0.0048 0.021 0.0383
Onchocerca volvulus Putative transporter 0.0048 0.021 0.0765
Plasmodium vivax isocitrate dehydrogenase [NADP], mitochondrial, putative 0.0032 0.0115 0.0139
Onchocerca volvulus 0.0015 0.0023 0.007
Echinococcus multilocularis neuropeptide Y receptor 0.0015 0.0023 0.0023
Trichomonas vaginalis PIKK family atypical protein kinase 0.0018 0.0039 0.0145
Mycobacterium ulcerans cytochrome P450 126A3 Cyp126A3 0.0014 0.0016 0.0425
Loa Loa (eye worm) hypothetical protein 0.0043 0.0182 0.0307
Echinococcus granulosus phosphatidylinositol 3 and 4 kinase 0.0018 0.0039 0.0075
Echinococcus granulosus chromobox protein 2 0.0013 0.0009 0.0017
Brugia malayi putative neuropeptide receptor 0.0015 0.0023 0.0039
Loa Loa (eye worm) pigment dispersing factor receptor c 0.0278 0.1527 0.2584
Onchocerca volvulus 0.0015 0.0023 0.007
Brugia malayi Associated with TFs and helicases family protein 0.0013 0.0009 0.0015
Loa Loa (eye worm) hypothetical protein 0.002 0.005 0.0085
Trichomonas vaginalis conserved hypothetical protein 0.0017 0.0032 0.0117
Trichomonas vaginalis sugar transporter, putative 0.0048 0.021 0.0779
Loa Loa (eye worm) major facilitator superfamily transporter 0.0048 0.021 0.0354
Loa Loa (eye worm) G-protein coupled receptor 0.0015 0.0023 0.0039
Plasmodium falciparum calcium-dependent protein kinase 5 0.0105 0.0534 0.0648
Echinococcus multilocularis cadherin EGF LAG seven pass G type receptor 0.0088 0.0439 0.0439
Plasmodium falciparum threonine--tRNA ligase 0.0019 0.0045 0.0054
Schistosoma mansoni cellular tumor antigen P53 0.0054 0.0241 0.0459
Loa Loa (eye worm) heterochromatin protein 1 0.0079 0.039 0.0659
Trypanosoma cruzi Phosphatidylinositol 3-kinase tor1 0.0018 0.0039 0.0627
Loa Loa (eye worm) hypothetical protein 0.0015 0.0023 0.0039
Schistosoma mansoni growth hormone secretagogue receptor 0.0015 0.0023 0.0043
Trichomonas vaginalis conserved hypothetical protein 0.0013 0.0009 0.0033
Trichomonas vaginalis chromodomain helicase DNA binding protein, putative 0.0028 0.0094 0.0347
Echinococcus granulosus Jumonji AT rich interactive domain 1B 0.0013 0.001 0.002
Plasmodium vivax lysine--tRNA ligase, putative 0.0076 0.0371 0.045
Schistosoma mansoni tar DNA-binding protein 0.0066 0.0314 0.0598
Trypanosoma cruzi threonyl-tRNA synthetase, putative 0.0019 0.0045 0.0715
Echinococcus granulosus neuropeptide receptor 0.0015 0.0023 0.0044
Mycobacterium tuberculosis Possible penicillin-binding protein 0.0262 0.1436 1
Mycobacterium tuberculosis Probable fatty-acid-CoA ligase FadD35 (fatty-acid-CoA synthetase) (fatty-acid-CoA synthase) 0.0019 0.0044 0.0196
Echinococcus multilocularis tm gpcr rhodopsin gpcr rhodopsin superfamily 0.0015 0.0023 0.0023
Trichomonas vaginalis conserved hypothetical protein 0.0015 0.0019 0.007
Trichomonas vaginalis esterase, putative 0.0041 0.017 0.0631
Echinococcus multilocularis somatostatin receptor 0.0015 0.0023 0.0023
Echinococcus granulosus g protein coupled receptor 0.0015 0.0023 0.0044
Loa Loa (eye worm) RNA recognition domain-containing protein domain-containing protein 0.0066 0.0314 0.0531
Loa Loa (eye worm) hypothetical protein 0.0048 0.021 0.0354
Mycobacterium tuberculosis Conserved hypothetical protein 0.0017 0.0032 0.011
Brugia malayi GTP-binding nuclear protein RAN/TC4 0.0026 0.0081 0.0137
Brugia malayi Dopamine receptor protein 1, putative (partial) 0.0015 0.0023 0.0039
Trypanosoma cruzi hexose transporter, putative 0.0106 0.0541 0.8747
Echinococcus granulosus solute carrier family 22 0.0048 0.021 0.04
Schistosoma mansoni sugar transporter 0.0048 0.021 0.0399
Echinococcus granulosus rhodopsin orphan GPCR 0.0015 0.0023 0.0044
Loa Loa (eye worm) nuclear hormone receptor family member nhr-1 0.0012 0.0005 0.0007
Echinococcus multilocularis biogenic amine (5HT) receptor 0.0015 0.0023 0.0023
Schistosoma mansoni opsin-like receptor 0.0015 0.0023 0.0043
Loa Loa (eye worm) hypothetical protein 0.0015 0.0023 0.0039
Onchocerca volvulus 0.0048 0.021 0.0765
Trichomonas vaginalis PIKK family atypical protein kinase 0.0018 0.0039 0.0145
Echinococcus granulosus orexin receptor type 2 0.0015 0.0023 0.0044
Onchocerca volvulus 0.0015 0.0023 0.007
Mycobacterium ulcerans histidyl-tRNA synthetase 0.0012 0.0001 0.0008
Echinococcus multilocularis hepatocyte nuclear factor 4 alpha 0.0012 0.0005 0.0005
Trichomonas vaginalis conserved hypothetical protein 0.0015 0.0019 0.007
Echinococcus multilocularis importin subunit beta 1 0.0035 0.0134 0.0134
Loa Loa (eye worm) major facilitator superfamily transporter 0.0048 0.021 0.0354
Trichomonas vaginalis chromodomain helicase DNA binding protein, putative 0.0013 0.0009 0.0033
Brugia malayi beta-lactamase 0.0041 0.017 0.0286
Trypanosoma brucei glucose transporter, putative 0.0106 0.0541 0.8748
Echinococcus granulosus rhodopsin orphan GPCR 0.0015 0.0023 0.0044
Trypanosoma brucei cytochrome P450, putative 0.0014 0.0016 0.0257
Schistosoma mansoni neuropeptide receptor 0.0015 0.0023 0.0043
Loa Loa (eye worm) hypothetical protein 0.0013 0.0009 0.0015
Trichomonas vaginalis chromodomain-helicase-DNA-binding protein, putative 0.0013 0.0009 0.0033
Schistosoma mansoni peptide (FMRFamide/somatostatin)-like receptor 0.0015 0.0023 0.0043
Onchocerca volvulus 0.0015 0.0023 0.007
Entamoeba histolytica hypothetical protein 0.0013 0.0009 0.0044
Trypanosoma cruzi glucose transporter, putative 0.0048 0.021 0.3384
Echinococcus granulosus histone lysine N methyltransferase MLL3 0.0018 0.004 0.0076
Toxoplasma gondii calcium-dependent protein kinase CDPK2A 0.0105 0.0534 0.0977
Trichomonas vaginalis conserved hypothetical protein 0.0106 0.0541 0.2014
Plasmodium falciparum phd finger protein, putative 0.003 0.0104 0.0125
Trichomonas vaginalis conserved hypothetical protein 0.0048 0.021 0.0779
Plasmodium falciparum chromodomain-helicase-DNA-binding protein 1 homolog, putative 0.0013 0.0009 0.0011
Echinococcus multilocularis Sugar transporter ERD6 protein 0.0048 0.021 0.021
Schistosoma mansoni ataxia telangiectasia mutated (atm) 0.0025 0.0078 0.0148
Toxoplasma gondii histidyl-tRNA synthetase (HisRS), putative 0.0012 0.0001 0.0001
Plasmodium vivax threonine--tRNA ligase, putative 0.0019 0.0045 0.0054
Loa Loa (eye worm) hypothetical protein 0.0015 0.0023 0.0039
Echinococcus multilocularis fmrfamide receptor 0.0015 0.0023 0.0023
Loa Loa (eye worm) hypothetical protein 0.0048 0.021 0.0354
Leishmania major glucose transporter, lmgt2 0.0106 0.0541 0.8747
Brugia malayi chromobox protein homolog 3 0.0045 0.019 0.032
Trypanosoma brucei lysyl-tRNA synthetase, putative 0.0076 0.0371 0.5998
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0015 0.0023 0.0043
Schistosoma mansoni chromodomain helicase DNA binding protein 0.0017 0.003 0.0057
Loa Loa (eye worm) hypothetical protein 0.0015 0.0023 0.0039
Echinococcus multilocularis Chromo domain 0.0013 0.0009 0.0009
Echinococcus granulosus dro:myosuppressin receptor 0.0015 0.0023 0.0044
Mycobacterium ulcerans hypothetical protein 0.0041 0.017 0.4567
Brugia malayi Bromodomain containing protein 0.0033 0.0126 0.0212
Brugia malayi Dopamine receptor protein 1 0.0015 0.0023 0.0039
Trypanosoma brucei bifunctional aminoacyl-tRNA synthetase, putative 0.0119 0.0618 1
Trypanosoma brucei glucose transporter, putative 0.0106 0.0541 0.8748
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0015 0.0023 0.0043
Schistosoma mansoni Tr4/Tr2 (homologue) 0.0012 0.0005 0.0008
Trichomonas vaginalis glucose transporter, putative 0.0106 0.0541 0.2014
Loa Loa (eye worm) hypothetical protein 0.002 0.005 0.0085
Echinococcus granulosus nuclear receptor 2DBD gamma 0.0012 0.0005 0.0009
Brugia malayi Serotonin/octopamine receptor family protein 7 0.0015 0.0023 0.0039
Onchocerca volvulus 0.0015 0.0023 0.007
Schistosoma mansoni chromobox protein 0.0079 0.039 0.0742
Schistosoma mansoni amine GPCR 0.0015 0.0023 0.0043
Schistosoma mansoni hypothetical protein 0.0043 0.0182 0.0346
Brugia malayi Hypothetical 52.5 kDa protein ZK945.1 in chromosome II, putative 0.0041 0.017 0.0286
Trichomonas vaginalis sugar transporter, putative 0.0048 0.021 0.0779
Giardia lamblia Sugar-proton symporter 0.0048 0.021 0.1073
Echinococcus granulosus Sugar transporter ERD6 protein 0.0048 0.021 0.04
Loa Loa (eye worm) hypothetical protein 0.0178 0.0956 0.1618
Echinococcus multilocularis guanine nucleotide binding protein G(s) subunit 0.0092 0.0459 0.0459
Brugia malayi Iron-sulfur cluster assembly accessory protein 0.0056 0.0255 0.0432
Trichomonas vaginalis conserved hypothetical protein 0.0021 0.0054 0.0201
Mycobacterium tuberculosis Conserved protein 0.0041 0.017 0.1081
Trypanosoma brucei myo-inositol/proton symporter (MIT) 0.0048 0.021 0.3385
Trypanosoma brucei phosphatidylinositol 3-related kinase, putative 0.0018 0.0039 0.0628
Loa Loa (eye worm) hypothetical protein 0.0048 0.021 0.0354
Mycobacterium leprae Probable lipase LipE 0.0041 0.017 0.304
Leishmania major importin beta-1 subunit, putative 0.0028 0.0096 0.1551
Onchocerca volvulus 0.0048 0.021 0.0765
Toxoplasma gondii anticodon binding domain-containing protein 0.0012 0.0001 0.0001
Loa Loa (eye worm) hypothetical protein 0.0015 0.0023 0.0039
Trichomonas vaginalis PIKK family atypical protein kinase 0.0018 0.0039 0.0145
Toxoplasma gondii 'chromo' (CHRromatin Organization MOdifier) domain-containing protein 0.0013 0.0009 0.0016
Leishmania major isocitrate dehydrogenase [NADP], mitochondrial precursor, putative 0.0032 0.0115 0.1857
Loa Loa (eye worm) hypothetical protein 0.0015 0.0023 0.0039
Trypanosoma cruzi cytochrome P450, putative 0.0014 0.0016 0.0255
Trypanosoma brucei glucose transporter 1E 0.0106 0.0541 0.8748
Loa Loa (eye worm) hypothetical protein 0.0015 0.0023 0.0039
Schistosoma mansoni histamine-responsive GPCR (AAF21638) 0.0015 0.0023 0.0043
Echinococcus granulosus tm gpcr rhodopsin 0.0015 0.0023 0.0044
Plasmodium vivax SET domain protein, putative 0.0062 0.0288 0.035
Loa Loa (eye worm) calcium/calmodulin-dependent protein kinase ID 0.0105 0.0533 0.0902
Toxoplasma gondii cell-cycle-associated protein kinase MAPK, putative 0.0552 0.3094 0.5668
Echinococcus granulosus aspartyl tRNA synthetase cytoplasmic 0.0011 0 0.0001
Trichomonas vaginalis glycyl-tRNA synthetase, putative 0.0012 0.0001 0.0001
Mycobacterium ulcerans cytochrome P450 185A4 Cyp185A4 0.0014 0.0016 0.0425
Toxoplasma gondii histone lysine acetyltransferase GCN5-A 0.0046 0.0199 0.0364
Brugia malayi bifunctional aminoacyl-tRNA synthetase 0.0102 0.0521 0.0881
Giardia lamblia Threonyl-tRNA synthetase 0.0019 0.0045 0.0227
Brugia malayi Sugar transporter family protein 0.0048 0.021 0.0354
Echinococcus multilocularis g protein coupled receptor 0.0015 0.0023 0.0023
Echinococcus multilocularis lysyl tRNA synthetase 0.0076 0.0371 0.0371
Plasmodium falciparum mitogen-activated protein kinase 2 0.0552 0.3094 0.3758
Mycobacterium ulcerans threonyl-tRNA synthetase 0.0019 0.0045 0.1193
Echinococcus granulosus calcium:calmodulin dependent protein kinase type 0.0105 0.0533 0.1017
Trypanosoma brucei glucose transporter, putative 0.0106 0.0541 0.8748
Echinococcus granulosus lipoxygenase domain containing protein 0.0043 0.0182 0.0347
Trichomonas vaginalis sugar transporter, putative 0.0048 0.021 0.0779
Entamoeba histolytica hypothetical protein 0.0028 0.0096 0.0492
Loa Loa (eye worm) neuropeptide F receptor 0.0015 0.0023 0.0039
Echinococcus granulosus Polycystic kidney disease protein 0.0043 0.0182 0.0347
Echinococcus multilocularis Nuclear hormone receptor family member nhr 41 0.0012 0.0005 0.0005
Echinococcus granulosus tm gpcr rhodopsin 0.0015 0.0023 0.0044
Loa Loa (eye worm) hypothetical protein 0.0015 0.0023 0.0039
Loa Loa (eye worm) hypothetical protein 0.0015 0.0023 0.0039
Schistosoma mansoni muscarinic acetylcholine (GAR) receptor 0.0015 0.0023 0.0043
Trypanosoma cruzi hexose transporter 0.0106 0.0541 0.8747
Echinococcus multilocularis synaptic vesicle 2 protein 0.0048 0.021 0.021
Echinococcus multilocularis g protein coupled receptor 0.0015 0.0023 0.0023
Leishmania major phosphatidylinositol 3-kinase, putative 0.0018 0.0039 0.0627
Echinococcus granulosus lysine specific demethylase 5A 0.0039 0.0161 0.0306
Schistosoma mansoni retinoic acid receptor RXR 0.0012 0.0005 0.0008
Brugia malayi RNA binding protein 0.0066 0.0314 0.0531
Toxoplasma gondii chromodomain helicase DNA binding protein CHD1/SWI2/SNF2 0.0013 0.0009 0.0016
Trichomonas vaginalis conserved hypothetical protein 0.0032 0.0115 0.0428
Trichomonas vaginalis PIKK family atypical protein kinase 0.0018 0.0039 0.0145
Trichomonas vaginalis conserved hypothetical protein 0.0015 0.0019 0.007
Chlamydia trachomatis lysine--tRNA ligase 0.0076 0.0371 1
Schistosoma mansoni cpg binding protein 0.0103 0.0522 0.0995
Echinococcus granulosus cpg binding protein 0.0103 0.0522 0.0996
Echinococcus granulosus neuropeptides capa receptor 0.0015 0.0023 0.0044
Plasmodium falciparum LCCL domain-containing protein 0.0043 0.0182 0.022
Mycobacterium tuberculosis Conserved protein 0.0041 0.017 0.1081
Schistosoma mansoni hypothetical protein 0.0088 0.0439 0.0836
Schistosoma mansoni jumonji/arid domain-containing protein 0.0039 0.0161 0.0305
Entamoeba histolytica acyl-coA synthetase, putative 0.0027 0.0089 0.0456
Mycobacterium ulcerans glycyl-tRNA synthetase 0.0019 0.0045 0.1193
Echinococcus multilocularis peregrin 0.0033 0.0126 0.0126
Onchocerca volvulus 0.0041 0.017 0.0616
Loa Loa (eye worm) hypothetical protein 0.0045 0.019 0.032
Entamoeba histolytica chromodomain-helicase-DNA-binding protein, putative 0.0013 0.0009 0.0044
Echinococcus granulosus rhodopsin orphan GPCR 0.0015 0.0023 0.0044
Trypanosoma cruzi importin beta-1 subunit, putative 0.0028 0.0096 0.1551
Echinococcus granulosus cytochrome P450 2K1 0.0014 0.0016 0.0031
Echinococcus granulosus Chromobox protein 3 0.0013 0.0009 0.0017
Brugia malayi Major Facilitator Superfamily protein 0.0048 0.021 0.0354
Trichomonas vaginalis chromodomain-helicase-DNA-binding protein, putative 0.0021 0.0054 0.0201
Trichomonas vaginalis chromodomain-helicase-DNA-binding protein, putative 0.0013 0.0009 0.0033
Loa Loa (eye worm) hypothetical protein 0.0054 0.0241 0.0408
Trypanosoma cruzi hypothetical protein, conserved 0.0017 0.0032 0.0508
Plasmodium falciparum conserved Plasmodium protein, unknown function 0.0085 0.0424 0.0514
Brugia malayi latrophilin 2 splice variant baaae 0.019 0.1023 0.1731
Loa Loa (eye worm) hypothetical protein 0.0083 0.0411 0.0695
Echinococcus multilocularis thyroid hormone receptor alpha 0.0012 0.0005 0.0005
Schistosoma mansoni steroid hormone receptor ad4bp 0.0012 0.0005 0.0008
Onchocerca volvulus 0.0043 0.0182 0.0662
Leishmania major myo-inositol/proton symporter (MIT) 0.0048 0.021 0.3384
Echinococcus granulosus COUP TF:Svp nuclear hormone receptor 0.0012 0.0005 0.0009
Echinococcus granulosus survival motor neuron protein 1 0.0275 0.1508 0.2875
Plasmodium falciparum calcium-dependent protein kinase 4 0.0105 0.0534 0.0648
Echinococcus granulosus synaptic vesicle 2 protein 0.0048 0.021 0.04
Brugia malayi calcium-independent alpha-latrotoxin receptor 2, putative 0.0088 0.0439 0.0741
Brugia malayi Steroid receptor seven-up type 2 0.0012 0.0005 0.0007
Leishmania major cytochrome p450-like protein 0.0014 0.0016 0.0255
Echinococcus multilocularis cpg binding protein 0.0103 0.0522 0.0522
Trichomonas vaginalis D-aminoacylase, putative 0.0041 0.017 0.0631
Echinococcus multilocularis orexin receptor type 2 0.0015 0.0023 0.0023
Mycobacterium ulcerans esterase/lipase LipP 0.0041 0.017 0.4567
Toxoplasma gondii cytochrome p450 superfamily protein 0.0014 0.0016 0.0029
Toxoplasma gondii histone lysine methyltransferase SET/SUV39 0.0062 0.0288 0.0528
Echinococcus multilocularis histone lysine N methyltransferase MLL3 0.0018 0.004 0.004
Mycobacterium ulcerans acyl-CoA synthetase 0.0027 0.0089 0.2401
Toxoplasma gondii HEAT repeat-containing protein 0.0035 0.0134 0.0245
Brugia malayi Sugar transporter family protein 0.0048 0.021 0.0354
Schistosoma mansoni chromobox protein-related (chromobox 1) (heterochromatin 1) 0.0013 0.0009 0.0017
Echinococcus multilocularis chromobox protein 1 0.0079 0.039 0.039
Onchocerca volvulus 0.0015 0.0023 0.007
Schistosoma mansoni glucose transporter 0.0048 0.021 0.0399
Trichomonas vaginalis bromodomain-containing protein, putative 0.0046 0.0199 0.0739
Schistosoma mansoni family S12 unassigned peptidase (S12 family) 0.0041 0.017 0.0323
Plasmodium falciparum GTP-binding nuclear protein RAN/TC4 0.0026 0.0081 0.0098
Plasmodium falciparum acyl-CoA synthetase 0.002 0.005 0.0061
Echinococcus multilocularis RUN 0.0043 0.0182 0.0182
Schistosoma mansoni glycyl-tRNA synthetase 0.0019 0.0045 0.0084
Onchocerca volvulus 0.0027 0.0089 0.0317
Schistosoma mansoni jumonji/arid domain-containing protein 0.0039 0.0161 0.0305
Echinococcus granulosus calcium dependent protein kinase 0.0098 0.0496 0.0947
Mycobacterium ulcerans sugar-transport integral membrane protein SugI 0.0048 0.021 0.5643
Schistosoma mansoni jumonji domain containing protein 0.0077 0.0374 0.0713
Loa Loa (eye worm) hypothetical protein 0.0048 0.021 0.0354
Brugia malayi RNA, U transporter 1 0.0099 0.0501 0.0848
Loa Loa (eye worm) hypothetical protein 0.0102 0.0521 0.0882
Loa Loa (eye worm) hypothetical protein 0.0012 0.0005 0.0007
Schistosoma mansoni mixed-lineage leukemia protein mll 0.0028 0.0095 0.0181
Schistosoma mansoni glucose transport protein 0.0342 0.189 0.3604
Onchocerca volvulus 0.0056 0.0255 0.0936
Brugia malayi Cytochrome P450 family protein 0.0014 0.0016 0.0027
Brugia malayi Calcium/calmodulin-dependent protein kinase type II alpha chain 0.0105 0.0533 0.0902
Brugia malayi hypothetical protein 0.0043 0.0182 0.0307
Chlamydia trachomatis threonine--tRNA ligase 0.0019 0.0045 0.1193
Brugia malayi hypothetical protein 0.0013 0.0009 0.0015
Trichomonas vaginalis chromodomain helicase DNA binding protein, putative 0.0028 0.0094 0.0347
Echinococcus multilocularis alpha 1A adrenergic receptor 0.0015 0.0023 0.0023
Echinococcus multilocularis neuropeptide receptor A26 0.0015 0.0023 0.0023
Plasmodium vivax sugar transporter, putative 0.0048 0.021 0.0254
Schistosoma mansoni hypothetical protein 0.0088 0.0439 0.0836
Echinococcus multilocularis glutamyl tRNA synthetase cytoplasmic 0.0102 0.0521 0.0521
Trichomonas vaginalis PIKK family atypical protein kinase 0.0018 0.0039 0.0145
Schistosoma mansoni hypothetical protein 0.0558 0.3128 0.5965
Schistosoma mansoni protein kinase 0.0105 0.0533 0.1016
Mycobacterium ulcerans cytochrome P450 136A2 Cyp136A2 0.0014 0.0016 0.0425
Trichomonas vaginalis chromodomain helicase DNA binding protein, putative 0.0028 0.0094 0.0347
Trypanosoma brucei importin beta-1 subunit, putative 0.0035 0.0134 0.2162
Loa Loa (eye worm) hypothetical protein 0.0048 0.021 0.0354
Mycobacterium ulcerans cytochrome P450 143A3 Cyp143A3 0.0014 0.0016 0.0425
Schistosoma mansoni sugar transporter 0.0048 0.021 0.0399
Leishmania major 4-coumarate:coa ligase-like protein 0.0027 0.0089 0.144
Mycobacterium tuberculosis Probable isocitrate dehydrogenase [NADP] Icd1 (oxalosuccinate decarboxylase) (IDH) (NADP+-specific ICDH) (IDP) 0.0032 0.0115 0.0697
Mycobacterium ulcerans cytochrome P450 105Q4 Cyp105Q4 0.0014 0.0016 0.0425
Echinococcus multilocularis solute carrier family 22 0.0048 0.021 0.021
Brugia malayi sulfakinin receptor protein 0.0015 0.0023 0.0039
Loa Loa (eye worm) hypothetical protein 0.0019 0.0045 0.0075
Trichomonas vaginalis sugar transporter, putative 0.0048 0.021 0.0779
Plasmodium vivax hypothetical protein, conserved 0.0041 0.017 0.0206
Brugia malayi neuropeptide F receptor 0.0015 0.0023 0.0039
Mycobacterium ulcerans cytochrome P450 140A5 Cyp140A5 0.0014 0.0016 0.0425
Toxoplasma gondii threonyl-tRNA synthetase family protein 0.0019 0.0045 0.0081
Loa Loa (eye worm) hypothetical protein 0.0041 0.017 0.0287
Loa Loa (eye worm) hypothetical protein 0.0015 0.0023 0.0039
Loa Loa (eye worm) hypothetical protein 0.0015 0.0023 0.0039
Loa Loa (eye worm) hypothetical protein 0.0015 0.0023 0.0039
Echinococcus multilocularis Threonyl tRNA synthetase, C 0.0019 0.0045 0.0045
Toxoplasma gondii prolyl-tRNA synthetase (ProRS) 0.0119 0.0618 0.1132
Mycobacterium leprae conserved hypothetical protein 0.0017 0.0032 0.031
Brugia malayi Cytochrome P450 family protein 0.0014 0.0016 0.0027
Trichomonas vaginalis sugar transporter, putative 0.0048 0.021 0.0779
Plasmodium vivax heterochromatin protein 1, putative 0.0013 0.0009 0.0011
Chlamydia trachomatis acylglycerophosphoethanolamine acyltransferase 0.002 0.005 0.1346
Brugia malayi lysyl-tRNA synthetase 0.0076 0.0371 0.0627
Trypanosoma brucei cytosine-specific DNA methylase, putative 0.002 0.0049 0.0784
Schistosoma mansoni cpg binding protein 0.0099 0.0501 0.0955
Echinococcus multilocularis GTP binding nuclear protein Ran 0.0026 0.0081 0.0081
Trichomonas vaginalis conserved hypothetical protein 0.0013 0.0009 0.0033
Brugia malayi Doublecortin family protein 0.0043 0.0182 0.0307
Brugia malayi hypothetical protein 0.0015 0.0023 0.0039
Loa Loa (eye worm) hypothetical protein 0.002 0.005 0.0085
Entamoeba histolytica FKBP-rapamycin associated protein (FRAP), putative 0.0018 0.0039 0.0199
Trypanosoma cruzi lysyl-tRNA synthetase, putative 0.0076 0.0371 0.5997
Trichomonas vaginalis PIKK family atypical protein kinase 0.0018 0.0039 0.0145
Leishmania major phosphatidylinositol kinase related protein, putative 0.0018 0.0039 0.063
Schistosoma mansoni chromobox protein-related (chromobox 1) (heterochromatin 1) 0.0013 0.0009 0.0017
Echinococcus multilocularis rhodopsin orphan GPCR 0.0015 0.0023 0.0023
Toxoplasma gondii sugar transporter ST3 0.0048 0.021 0.0383
Leishmania major 4-coumarate:coa ligase-like protein 0.0027 0.0089 0.144
Trypanosoma brucei THT1 - hexose transporter, putative 0.0106 0.0541 0.8748
Echinococcus multilocularis DNA methyltransferase 2, putative 0.002 0.0049 0.0049
Echinococcus multilocularis calcium dependent protein kinase 0.0098 0.0496 0.0496
Echinococcus multilocularis g protein linked acetylcholine receptor gar 2a 0.0015 0.0023 0.0023
Onchocerca volvulus Dopamine\/Ecdysteroid receptor homolog 0.0015 0.0023 0.007
Echinococcus granulosus jumonji domain containing protein 0.0041 0.017 0.0324
Brugia malayi Nuclear hormone receptor family member nhr-19 0.0012 0.0005 0.0007
Mycobacterium ulcerans hypothetical protein 0.0027 0.0089 0.2401
Loa Loa (eye worm) hypothetical protein 0.0048 0.021 0.0354
Schistosoma mansoni neuropeptide receptor 0.0015 0.0023 0.0043
Onchocerca volvulus 0.0099 0.0501 0.1852
Echinococcus granulosus chromodomain helicase DNA binding protein 1 0.0013 0.0009 0.0017
Echinococcus granulosus thyrotropin releasing hormone receptor 0.0015 0.0023 0.0044
Leishmania major target of rapamycin (TOR) kinase 1, putative 0.0018 0.0039 0.0627
Onchocerca volvulus 0.0015 0.0023 0.007
Trichomonas vaginalis sugar transporter, putative 0.0048 0.021 0.0779
Loa Loa (eye worm) RNA binding protein 0.0066 0.0314 0.0531
Mycobacterium ulcerans cytochrome P450 188A3 Cyp188A3 0.0014 0.0016 0.0425
Trypanosoma cruzi hypothetical protein, conserved 0.0041 0.017 0.2739
Echinococcus granulosus 5'partial|histone lysine N methyltransferase SETDB2 0.0058 0.0268 0.051
Loa Loa (eye worm) TAR-binding protein 0.0066 0.0314 0.0531
Trichomonas vaginalis sugar transporter, putative 0.0048 0.021 0.0779
Loa Loa (eye worm) hypothetical protein 0.0015 0.0023 0.0039
Trichomonas vaginalis chromobox protein, putative 0.0048 0.0209 0.0777
Echinococcus granulosus neuropeptide FF receptor 2 0.0015 0.0023 0.0044
Echinococcus granulosus neuropeptide Y receptor 0.0015 0.0023 0.0044
Trypanosoma cruzi hypothetical protein, conserved 0.0041 0.017 0.2739
Brugia malayi ORL1-like opioid receptor 0.0015 0.0023 0.0039
Mycobacterium ulcerans long-chain fatty-acid CoA ligase 0.0027 0.0089 0.2401
Echinococcus multilocularis allatostatin A receptor 0.0015 0.0023 0.0023
Mycobacterium ulcerans beta-lactamase 0.0041 0.017 0.4567
Plasmodium falciparum protein kinase 6 0.145 0.8233 1
Brugia malayi CHD4 protein 0.0017 0.003 0.0051
Onchocerca volvulus 0.0048 0.021 0.0765
Echinococcus granulosus geminin 0.0558 0.3128 0.5966
Loa Loa (eye worm) hypothetical protein 0.0013 0.0009 0.0015
Schistosoma mansoni chromobox protein 0.0079 0.039 0.0742
Onchocerca volvulus 0.0015 0.0023 0.007
Brugia malayi PHD-finger family protein 0.0013 0.0011 0.0018
Trypanosoma cruzi hexose transporter, putative 0.0048 0.021 0.3384
Trichomonas vaginalis PIKK family atypical protein kinase 0.0018 0.0039 0.0145
Loa Loa (eye worm) hypothetical protein 0.0015 0.0023 0.0039
Onchocerca volvulus 0.0015 0.0023 0.007
Mycobacterium tuberculosis Probable threonyl-tRNA synthetase ThrS (threonine-tRNA synthetase)(ThrRS) (threonine-tRNA ligase) 0.0019 0.0045 0.02
Trypanosoma brucei isocitrate dehydrogenase, putative 0.0032 0.0115 0.1858
Trypanosoma cruzi GTP-binding nuclear protein rtb2, putative 0.0026 0.0081 0.1309
Schistosoma mansoni hypothetical protein 0.0015 0.0023 0.0043
Echinococcus multilocularis neuropeptide Y receptor 0.0015 0.0023 0.0023
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0015 0.0023 0.0043
Trichomonas vaginalis sugar transporter, putative 0.0048 0.021 0.0779
Brugia malayi threonyl-tRNA synthetase, cytoplasmic 0.0019 0.0045 0.0075
Trichomonas vaginalis penicillin-binding protein, putative 0.0041 0.017 0.0631
Brugia malayi hypothetical protein 0.0015 0.0023 0.0039

Activities

Activity type Activity value Assay description Source Reference
Potency (functional) 3.6964 uM PUBCHEM_BIOASSAY: Primary qHTS for delayed death inhibitors of the malarial parasite plastid, 96 hour incubation. (Class of assay: confirmatory) [Related pubchem assays (depositor defined):AID488745, AID488752, AID488774, AID504848, AID504850] ChEMBL. No reference
Potency (functional) 8.2753 uM PUBCHEM_BIOASSAY: Primary qHTS for delayed death inhibitors of the malarial parasite plastid, 48 hour incubation. (Class of assay: confirmatory) [Related pubchem assays (depositor defined):AID488752, AID488774, AID504848, AID504850] ChEMBL. No reference
Potency (functional) = 10 um PUBCHEM_BIOASSAY: VP16 counterscreen qHTS for inhibitors of ROR gamma transcriptional activity. (Class of assay: confirmatory) ChEMBL. No reference
Potency (functional) 10.3225 uM PUBCHEM_BIOASSAY: qHTS Assay for Inhibitors of RanGTP induced Rango (Ran-regulated importin-beta cargo) - Importin beta complex dissociation. (Class of assay: confirmatory) [Related pubchem assays (depositor defined):AID540262] ChEMBL. No reference
Potency (binding) = 22.3872 um PUBCHEM_BIOASSAY: qHTS for Inhibitors of Tau Fibril Formation, Thioflavin T Binding. (Class of assay: confirmatory) [Related pubchem assays: 596 ] ChEMBL. No reference
Potency (functional) 28.1838 uM PubChem BioAssay. qHTS for Antagonists of gsp, the Etiologic Mutation Responsible for Fibrous Dysplasia/McCune-Albright Syndrome: qHTS. (Class of assay: confirmatory) ChEMBL. No reference
Potency (functional) 29.0929 uM PubChem BioAssay. A quantitative high throughput screen for small molecules that induce DNA re-replication in MCF 10a normal breast cells. (Class of assay: confirmatory) ChEMBL. No reference
Potency (functional) 31.6228 uM PUBCHEM_BIOASSAY: qHTS Assay for Inhibitors of 15-hLO-2 (15-human lipoxygenase 2). (Class of assay: confirmatory) [Related pubchem assays (depositor defined):AID2312, AID2537, AID2702] ChEMBL. No reference
Potency (functional) 39.8107 uM PubChem BioAssay. Inhibitors of USP1/UAF1: Primary Screen. (Class of assay: confirmatory) ChEMBL. No reference
Potency (functional) 50.1187 uM PubChem BioAssay. qHTS for Agonist of gsp, the Etiologic Mutation Responsible for Fibrous Dysplasia/McCune-Albright Syndrome: qHTS. (Class of assay: confirmatory) ChEMBL. No reference
Potency (functional) 112.2018 uM PUBCHEM_BIOASSAY: qHTS Assay for Inhibitors of Rango (Ran-regulated importin-beta cargo) - Importin beta complex formation. (Class of assay: confirmatory) [Related pubchem assays (depositor defined):AID540273] ChEMBL. No reference
Potency (functional) 223.8721 uM PubChem BioAssay. Inhibitors of Secretory Acid Sphingomyelinase (S-ASM): qHTS. (Class of assay: confirmatory) ChEMBL. No reference

Phenotypes

Whole-cell/tissue/organism interactions

Species name Source Reference Is orphan
Plasmodium falciparum ChEMBL23

Many chemical entities in TDR Targets come from high-throughput screenings with whole cells or tissue samples, and not all assayed compounds have been tested against a single a single target protein, probably because they get ruled out during screening process. Even if these compounds may have not been of interest in the original screening, they may come as interesting leads for other screening assays. Furthermore, we may be able to propose drug-target associations using chemical similarities and network patterns.

Annotated phenotypes:

We have no manually annotated phenotypes for this drug. What does this mean? / Care to help?
In TDR Targets, information about phenotypes that are caused by drugs, or by genetic manipulation of cells (e.g. gene knockouts or knockdowns) is manually curated from the literature. These descriptions help to describe the potential of the target for drug development. If no information is available for this gene or if the information is incomplete, this may mean that i) the papers containing this information either appeared after the curation effort for this organism was carried out or they were inadvertently missed by curators; or that ii) the curation effort for this organism has not yet started.
 
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External resources for this compound

Bibliographic References

No literature references available for this target.

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