Detailed information for compound 1316743

Basic information

Technical information
  • TDR Targets ID: 1316743
  • Name: (E)-2-(5-acetylthiophen-2-yl)-3-pyridin-4-ylp rop-2-enenitrile
  • MW: 254.307 | Formula: C14H10N2OS
  • H donors: 0 H acceptors: 3 LogP: 2.37 Rotable bonds: 3
    Rule of 5 violations (Lipinski): 1
  • SMILES: N#C/C(=C\c1ccncc1)/c1ccc(s1)C(=O)C
  • InChi: 1S/C14H10N2OS/c1-10(17)13-2-3-14(18-13)12(9-15)8-11-4-6-16-7-5-11/h2-8H,1H3/b12-8+
  • InChiKey: DIJQYQNOAFZYBN-XYOKQWHBSA-N  


Substructure search Similarity search

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Synonyms

  • 2-(5-acetylthiophen-2-yl)-3-pyridin-4-ylprop-2-enenitrile
  • (E)-2-(5-acetyl-2-thienyl)-3-(4-pyridyl)prop-2-enenitrile
  • 2-(5-acetyl-2-thienyl)-3-(4-pyridyl)prop-2-enenitrile
  • 2-(5-acetyl-2-thienyl)-3-(4-pyridyl)acrylonitrile
  • (E)-2-(5-acetyl-2-thienyl)-3-(4-pyridyl)acrylonitrile
  • 2-(5-ethanoylthiophen-2-yl)-3-pyridin-4-yl-prop-2-enenitrile
  • (E)-2-(5-ethanoylthiophen-2-yl)-3-pyridin-4-yl-prop-2-enenitrile
  • 9L-023
  • ZINC01403230

Targets

Known targets for this compound

Species Target name Source Bibliographic reference
Homo sapiens glucagon-like peptide 1 receptor Starlite/ChEMBL No references
Homo sapiens ataxin 2 Starlite/ChEMBL No references
Homo sapiens geminin, DNA replication inhibitor Starlite/ChEMBL No references
Homo sapiens snurportin 1 No references
Homo sapiens glycoprotein hormones, alpha polypeptide Starlite/ChEMBL No references
Homo sapiens RAN, member RAS oncogene family No references
Homo sapiens muscleblind-like splicing regulator 1 Starlite/ChEMBL No references
Homo sapiens peptidylprolyl cis/trans isomerase, NIMA-interacting 1 Starlite/ChEMBL No references
Homo sapiens karyopherin (importin) beta 1 No references

Predicted pathogen targets for this compound

By orthology
Species Potential target Known druggable target/s Ortholog Group
Echinococcus multilocularis muscleblind protein 1 Get druggable targets OG5_132352 All targets in OG5_132352
Schistosoma mansoni importin beta-1 Get druggable targets OG5_127843 All targets in OG5_127843
Leishmania major peptidyl-prolyl cis-trans isomerase/rotamase, putative,PPIase, putative Get druggable targets OG5_128367 All targets in OG5_128367
Cryptosporidium parvum importin/karyopherin Get druggable targets OG5_127843 All targets in OG5_127843
Brugia malayi Pin1-type peptidyl-prolyl cis-trans isomerase, BmPin1 Get druggable targets OG5_128367 All targets in OG5_128367
Echinococcus multilocularis importin subunit beta 1 Get druggable targets OG5_127843 All targets in OG5_127843
Trypanosoma cruzi peptidyl-prolyl cis-trans isomerase Get druggable targets OG5_128367 All targets in OG5_128367
Trypanosoma brucei importin beta-1 subunit, putative Get druggable targets OG5_127843 All targets in OG5_127843
Toxoplasma gondii peptidylprolyl isomerase Get druggable targets OG5_128367 All targets in OG5_128367
Trypanosoma cruzi importin beta-1 subunit, putative Get druggable targets OG5_127843 All targets in OG5_127843
Echinococcus granulosus importin subunit beta 1 Get druggable targets OG5_127843 All targets in OG5_127843
Echinococcus granulosus GTP binding nuclear protein Ran Get druggable targets OG5_127514 All targets in OG5_127514
Brugia malayi GTP-binding nuclear protein RAN/TC4 Get druggable targets OG5_127514 All targets in OG5_127514
Leishmania infantum peptidyl-prolyl cis-trans isomerase/rotamase, putative,PPIase, putative Get druggable targets OG5_128367 All targets in OG5_128367
Loa Loa (eye worm) hypothetical protein Get druggable targets OG5_132352 All targets in OG5_132352
Trichomonas vaginalis importin beta-1, putative Get druggable targets OG5_127843 All targets in OG5_127843
Trichomonas vaginalis conserved hypothetical protein Get druggable targets OG5_128367 All targets in OG5_128367
Trichomonas vaginalis ran, putative Get druggable targets OG5_127514 All targets in OG5_127514
Loa Loa (eye worm) Pin1-type peptidyl-prolyl cis-trans isomerase Get druggable targets OG5_128367 All targets in OG5_128367
Trypanosoma brucei gambiense peptidyl-prolyl cis-trans isomerase/rotamase, putative,PPIase, putative Get druggable targets OG5_128367 All targets in OG5_128367
Schistosoma mansoni ran Get druggable targets OG5_127514 All targets in OG5_127514
Trypanosoma brucei gambiense GTP-binding nuclear protein rtb2, putative Get druggable targets OG5_127514 All targets in OG5_127514
Trypanosoma brucei peptidyl-prolyl cis-trans isomerase/rotamase, putative Get druggable targets OG5_128367 All targets in OG5_128367
Entamoeba histolytica Ran family GTPase Get druggable targets OG5_127514 All targets in OG5_127514
Trypanosoma cruzi GTP-binding nuclear protein rtb2, putative Get druggable targets OG5_127514 All targets in OG5_127514
Giardia lamblia GTP-binding nuclear protein RAN/TC4 Get druggable targets OG5_127514 All targets in OG5_127514
Schistosoma japonicum Importin subunit beta, putative Get druggable targets OG5_127843 All targets in OG5_127843
Echinococcus granulosus muscleblind protein Get druggable targets OG5_132352 All targets in OG5_132352
Schistosoma japonicum ko:K09578 peptidyl-prolyl cis-trans isomerase NIMA-interacting 1, putative Get druggable targets OG5_128367 All targets in OG5_128367
Cryptosporidium parvum GTP-binding nuclear protein ran/tc4 Get druggable targets OG5_127514 All targets in OG5_127514
Theileria parva peptidyl-prolyl cis-trans isomerase, putative Get druggable targets OG5_128367 All targets in OG5_128367
Trichomonas vaginalis rotamase, putative Get druggable targets OG5_128367 All targets in OG5_128367
Trichomonas vaginalis Importin beta-1 subunit, putative Get druggable targets OG5_127843 All targets in OG5_127843
Trichomonas vaginalis Importin beta-1 subunit, putative Get druggable targets OG5_127843 All targets in OG5_127843
Trypanosoma brucei importin beta-1 subunit, putative Get druggable targets OG5_127843 All targets in OG5_127843
Plasmodium falciparum GTP-binding nuclear protein RAN/TC4 Get druggable targets OG5_127514 All targets in OG5_127514
Plasmodium vivax importin-beta 2, putative Get druggable targets OG5_127843 All targets in OG5_127843
Leishmania braziliensis peptidyl-prolyl cis-trans isomerase/rotamase, putative,PPIase, putative Get druggable targets OG5_128367 All targets in OG5_128367
Trypanosoma congolense importin beta-1 subunit, putative Get druggable targets OG5_127843 All targets in OG5_127843
Trypanosoma congolense GTP-binding nuclear protein rtb2, putative Get druggable targets OG5_127514 All targets in OG5_127514
Leishmania donovani importin beta-1 subunit, putative Get druggable targets OG5_127843 All targets in OG5_127843
Leishmania major importin beta-1 subunit, putative Get druggable targets OG5_127843 All targets in OG5_127843
Theileria parva GTP-binding nuclear protein ran, putative Get druggable targets OG5_127514 All targets in OG5_127514
Plasmodium berghei importin beta, putative Get druggable targets OG5_127843 All targets in OG5_127843
Trypanosoma cruzi peptidyl-prolyl cis-trans isomerase Get druggable targets OG5_128367 All targets in OG5_128367
Entamoeba histolytica peptidyl-prolyl cis-trans isomerase, putative Get druggable targets OG5_128367 All targets in OG5_128367
Plasmodium knowlesi GTP-binding nuclear protein RAN/TC4, putative Get druggable targets OG5_127514 All targets in OG5_127514
Trypanosoma cruzi GTP-binding nuclear protein rtb2, putative Get druggable targets OG5_127514 All targets in OG5_127514
Leishmania mexicana GTP-binding protein, putative Get druggable targets OG5_127514 All targets in OG5_127514
Loa Loa (eye worm) GTP-binding nuclear protein RAN/TC4 Get druggable targets OG5_127514 All targets in OG5_127514
Echinococcus multilocularis muscleblind protein Get druggable targets OG5_132352 All targets in OG5_132352
Echinococcus granulosus snurportin 1 Get druggable targets OG5_131808 All targets in OG5_131808
Candida albicans peptidylprolyl cis/trans isomerase isolated by functional complementation of S. cerevisiae ESS1 (YJR017C) which interacts with t Get druggable targets OG5_128367 All targets in OG5_128367
Candida albicans Ran, Ras family GTP-binding protein Get druggable targets OG5_127514 All targets in OG5_127514
Plasmodium yoelii importin beta-1 subunit Get druggable targets OG5_127843 All targets in OG5_127843
Leishmania infantum importin beta-1 subunit, putative Get druggable targets OG5_127843 All targets in OG5_127843
Leishmania donovani GTP-binding protein, putative Get druggable targets OG5_127514 All targets in OG5_127514
Schistosoma japonicum Importin subunit beta-1, putative Get druggable targets OG5_127843 All targets in OG5_127843
Brugia malayi Importin beta-1 subunit Get druggable targets OG5_127843 All targets in OG5_127843
Entamoeba histolytica hypothetical protein Get druggable targets OG5_127843 All targets in OG5_127843
Trypanosoma brucei gambiense importin beta-1 subunit, putative Get druggable targets OG5_127843 All targets in OG5_127843
Leishmania mexicana importin beta-1 subunit, putative Get druggable targets OG5_127843 All targets in OG5_127843
Babesia bovis GTP-binding nuclear protein Ran Get druggable targets OG5_127514 All targets in OG5_127514
Brugia malayi RNA, U transporter 1 Get druggable targets OG5_131808 All targets in OG5_131808
Leishmania braziliensis GTP-binding protein, putative Get druggable targets OG5_127514 All targets in OG5_127514
Candida albicans karyopherin-beta Get druggable targets OG5_127843 All targets in OG5_127843
Leishmania mexicana peptidyl-prolyl cis-trans isomerase/rotamase, putative,PPIase, putative Get druggable targets OG5_128367 All targets in OG5_128367
Neospora caninum GTP-binding nuclear protein Ran, related Get druggable targets OG5_127514 All targets in OG5_127514
Echinococcus granulosus expressed protein Get druggable targets OG5_128367 All targets in OG5_128367
Echinococcus multilocularis GTP binding nuclear protein Ran Get druggable targets OG5_127514 All targets in OG5_127514
Neospora caninum hypothetical protein Get druggable targets OG5_127843 All targets in OG5_127843
Leishmania infantum GTP-binding protein, putative Get druggable targets OG5_127514 All targets in OG5_127514
Plasmodium vivax GTP-binding nuclear protein RAN/TC4, putative Get druggable targets OG5_127514 All targets in OG5_127514
Candida albicans Ran, Ras family GTP-binding protein Get druggable targets OG5_127514 All targets in OG5_127514
Echinococcus multilocularis snurportin 1 Get druggable targets OG5_131808 All targets in OG5_131808
Babesia bovis importin beta subunit, putative Get druggable targets OG5_127843 All targets in OG5_127843
Leishmania braziliensis importin beta-1 subunit, putative Get druggable targets OG5_127843 All targets in OG5_127843
Plasmodium falciparum importin beta, putative Get druggable targets OG5_127843 All targets in OG5_127843
Candida albicans peptidylprolyl cis/trans isomerase isolated by functional complementation of S. cerevisiae ESS1 (YJR017C) which interacts with t Get druggable targets OG5_128367 All targets in OG5_128367
Schistosoma japonicum ko:K07936 GTP-binding nuclear protein Ran, putative Get druggable targets OG5_127514 All targets in OG5_127514
Cryptosporidium hominis importin-beta2 Get druggable targets OG5_127843 All targets in OG5_127843
Schistosoma mansoni rotamase Get druggable targets OG5_128367 All targets in OG5_128367
Toxoplasma gondii HEAT repeat-containing protein Get druggable targets OG5_127843 All targets in OG5_127843
Schistosoma japonicum Snurportin-1, putative Get druggable targets OG5_131808 All targets in OG5_131808
Cryptosporidium hominis GTP-binding nuclear protein ran/tc4 Get druggable targets OG5_127514 All targets in OG5_127514
Toxoplasma gondii GTP-binding nuclear protein ran/tc4 Get druggable targets OG5_127514 All targets in OG5_127514
Plasmodium knowlesi importin beta, putative Get druggable targets OG5_127843 All targets in OG5_127843
Leishmania major GTP-binding protein, putative Get druggable targets OG5_127514 All targets in OG5_127514
Trypanosoma brucei GTP-binding nuclear protein rtb2, putative Get druggable targets OG5_127514 All targets in OG5_127514
Echinococcus multilocularis expressed protein Get druggable targets OG5_128367 All targets in OG5_128367
Plasmodium berghei GTP-binding nuclear protein RAN/TC4, putative Get druggable targets OG5_127514 All targets in OG5_127514
Trypanosoma congolense peptidyl-prolyl cis-trans isomerase/rotamase, putative Get druggable targets OG5_128367 All targets in OG5_128367
Loa Loa (eye worm) hypothetical protein Get druggable targets OG5_132352 All targets in OG5_132352
Theileria parva importin beta, putative Get druggable targets OG5_127843 All targets in OG5_127843
Loa Loa (eye worm) nucleolar RNA-associated protein alpha Get druggable targets OG5_131808 All targets in OG5_131808
Neospora caninum peptidyl-prolyl cis-trans isomerase NIMA- interacting 1, putative Get druggable targets OG5_128367 All targets in OG5_128367
Babesia bovis peptidyl-prolyl cis-trans isomerase, putative Get druggable targets OG5_128367 All targets in OG5_128367
Plasmodium yoelii GTP-binding nuclear protein ran/tc4 Get druggable targets OG5_127514 All targets in OG5_127514
Candida albicans karyopherin-beta Get druggable targets OG5_127843 All targets in OG5_127843
Trichomonas vaginalis rotamase, putative Get druggable targets OG5_128367 All targets in OG5_128367
Schistosoma mansoni hypothetical protein Get druggable targets OG5_131808 All targets in OG5_131808
Brugia malayi Muscleblind-like protein Get druggable targets OG5_132352 All targets in OG5_132352
Schistosoma mansoni ran Get druggable targets OG5_127514 All targets in OG5_127514
Leishmania donovani peptidyl-prolyl cis-trans isomerase/rotamase, putative Get druggable targets OG5_128367 All targets in OG5_128367
Loa Loa (eye worm) hypothetical protein Get druggable targets OG5_127843 All targets in OG5_127843
By sequence similarity to non orthologous known druggable targets
Species Potential target Known druggable target Length Alignment span Identity
Loa Loa (eye worm) pigment dispersing factor receptor c glucagon-like peptide 1 receptor 463 aa 388 aa 25.8 %
Toxoplasma gondii intraflagellar transport protein 172, putative glycoprotein hormones, alpha polypeptide 116 aa 94 aa 26.6 %
Brugia malayi Hypothetical 65.5 kDa Trp-Asp repeats containing protein F02E8.5 inchromosome X geminin, DNA replication inhibitor 209 aa 176 aa 27.8 %
Leishmania major peptidyl-prolyl cis-trans isomerase, putative peptidylprolyl cis/trans isomerase, NIMA-interacting 1 163 aa 133 aa 27.8 %
Obtained from network model

Ranking Plot

Putative Targets List

Species Potential target Raw Global Species
Trichomonas vaginalis sugar transporter, putative 0.0047 0.0216 0.0778
Trypanosoma brucei Aminoacyl-tRNA editing domain containing protein, putative 0.0017 0.0038 0.0509
Echinococcus multilocularis glutamyl tRNA synthetase cytoplasmic 0.0101 0.0528 0.0521
Mycobacterium ulcerans sugar-transport integral membrane protein SugI 0.0047 0.0216 0.5643
Mycobacterium ulcerans cytochrome P450 188A3 Cyp188A3 0.0014 0.0023 0.0427
Trichomonas vaginalis chromodomain helicase DNA binding protein, putative 0.0027 0.01 0.0346
Schistosoma mansoni cytochrome P450 0.0014 0.0023 0.0043
Trypanosoma cruzi peptidyl-prolyl cis-trans isomerase 0.0012 0.0012 0.0091
Mycobacterium ulcerans cytochrome P450 143A4 Cyp143A4 0.0014 0.0023 0.0427
Trypanosoma brucei importin beta-1 subunit, putative 0.0035 0.0144 0.2217
Toxoplasma gondii 'chromo' (CHRromatin Organization MOdifier) domain-containing protein 0.0013 0.0015 0.0016
Trypanosoma brucei THT1 - hexose transporter, putative 0.0104 0.0547 0.8748
Trichomonas vaginalis conserved hypothetical protein 0.0014 0.0025 0.0069
Echinococcus multilocularis histone lysine N methyltransferase SETMAR 0.0061 0.0295 0.0289
Brugia malayi Protein cec-1. 0.0013 0.0015 0.0015
Wolbachia endosymbiont of Brugia malayi exonuclease III 0.0022 0.0071 0.3059
Brugia malayi Pre-SET motif family protein 0.0416 0.2361 0.4011
Trichomonas vaginalis conserved hypothetical protein 0.0047 0.0216 0.0778
Schistosoma mansoni hypothetical protein 0.0372 0.2106 0.4014
Schistosoma mansoni aspartyl-tRNA synthetase 0.0011 0.0007 0.0013
Trichomonas vaginalis glucose transporter, putative 0.0104 0.0547 0.2012
Leishmania major isocitrate dehydrogenase [NADP], mitochondrial precursor, putative 0.0031 0.0122 0.1859
Trypanosoma brucei glucose transporter, putative 0.0104 0.0547 0.8748
Trypanosoma cruzi threonyl-tRNA synthetase, putative 0.0019 0.0051 0.0715
Trichomonas vaginalis sugar transporter, putative 0.0047 0.0216 0.0778
Mycobacterium ulcerans long-chain-fatty-acid-CoA ligase 0.0027 0.0096 0.2396
Loa Loa (eye worm) hypothetical protein 0.0047 0.0216 0.0356
Trypanosoma brucei myo-inositol/proton symporter (MIT) 0.0047 0.0216 0.3384
Brugia malayi hypothetical protein 0.0013 0.0015 0.0015
Echinococcus multilocularis histone lysine N methyltransferase MLL3 0.0018 0.0046 0.004
Mycobacterium ulcerans cytochrome P450 187A5 Cyp187A5 0.0014 0.0023 0.0427
Schistosoma mansoni nuclear transcription factor X-box binding 1 (nfx1) 0.0047 0.0216 0.0412
Echinococcus granulosus solute carrier family 22 0.0047 0.0216 0.04
Trichomonas vaginalis chromobox protein, putative 0.0078 0.0395 0.1446
Mycobacterium tuberculosis Probable esterase/lipase LipP 0.004 0.0176 0.108
Brugia malayi CXXC zinc finger family protein 0.0097 0.0507 0.0853
Trichomonas vaginalis conserved hypothetical protein 0.0013 0.0015 0.0032
Trichomonas vaginalis sugar transporter, putative 0.0047 0.0216 0.0778
Mycobacterium ulcerans acyl-CoA synthetase 0.0027 0.0096 0.2396
Trichomonas vaginalis myo-inositol transporter, putative 0.0047 0.0216 0.0778
Trichomonas vaginalis sugar transporter, putative 0.0047 0.0216 0.0778
Brugia malayi Importin beta-1 subunit 0.0035 0.0144 0.0233
Plasmodium vivax histone acetyltransferase GCN5, putative 0.0045 0.0205 0.0241
Schistosoma mansoni mixed-lineage leukemia protein mll 0.0138 0.0744 0.1418
Trichomonas vaginalis glucose transporter, putative 0.0104 0.0547 0.2012
Echinococcus granulosus Ataxin 2 N terminaldomain containing protein 0.0014 0.002 0.0027
Brugia malayi Disco-interacting protein 2 homolog 0.0038 0.0164 0.0268
Mycobacterium ulcerans long-chain fatty-acid CoA ligase 0.0027 0.0096 0.2396
Trypanosoma cruzi phosphatidylinositol kinase related protein, putative 0.0025 0.0085 0.1261
Echinococcus multilocularis guanine nucleotide binding protein G(s) subunit 0.0144 0.0781 0.0776
Leishmania major glucose transporter, lmgt2 0.0104 0.0547 0.8747
Trichomonas vaginalis PIKK family atypical protein kinase 0.0018 0.0046 0.0145
Entamoeba histolytica peptidyl-prolyl cis-trans isomerase, putative 0.0039 0.017 0.0838
Trichomonas vaginalis conserved hypothetical protein 0.0014 0.0025 0.0069
Trypanosoma cruzi hexose transporter, putative 0.0047 0.0216 0.3384
Brugia malayi Muscleblind-like protein 0.018 0.0991 0.1677
Echinococcus granulosus solute carrier family 2 facilitated glucose 0.0336 0.1896 0.3607
Trichomonas vaginalis sugar transporter, putative 0.0047 0.0216 0.0778
Echinococcus granulosus dnaJ subfamily B 0.0911 0.5246 1
Loa Loa (eye worm) pre-SET domain-containing protein family protein 0.0416 0.2361 0.4011
Onchocerca volvulus Heterochromatin protein 1 homolog 0.0047 0.0215 0.0745
Mycobacterium ulcerans esterase/lipase LipP 0.004 0.0176 0.456
Loa Loa (eye worm) latrophilin receptor protein 2 0.0086 0.0444 0.0746
Schistosoma mansoni hypothetical protein 0.0014 0.0023 0.0043
Trichomonas vaginalis PIKK family atypical protein kinase 0.0018 0.0046 0.0145
Trichomonas vaginalis PIKK family atypical protein kinase 0.0018 0.0046 0.0145
Loa Loa (eye worm) hypothetical protein 0.004 0.0176 0.0288
Echinococcus granulosus Polycystic kidney disease protein 0.0042 0.0188 0.0347
Loa Loa (eye worm) cytochrome P450 family protein 0.0014 0.0023 0.0027
Mycobacterium ulcerans sugar transporter 0.0047 0.0216 0.5643
Loa Loa (eye worm) hypothetical protein 0.0047 0.0216 0.0356
Echinococcus granulosus tar DNA binding protein 0.0065 0.0321 0.06
Brugia malayi hypothetical protein 0.0047 0.0216 0.0356
Echinococcus granulosus Threonyl tRNA synthetase C 0.0019 0.0051 0.0085
Brugia malayi Phosphatidylinositol 3- and 4-kinase family protein 0.0018 0.0046 0.0066
Schistosoma mansoni chromobox protein 0.0013 0.0015 0.0029
Schistosoma mansoni NADP-specific isocitrate dehydrogenase 0.0031 0.0122 0.0232
Echinococcus granulosus geminin 0.0749 0.4301 0.8197
Echinococcus granulosus beta LACTamase domain containing family member 0.004 0.0176 0.0323
Schistosoma mansoni histone-lysine n-methyltransferase setb1 0.0061 0.0295 0.0563
Schistosoma mansoni histidyl-tRNA synthetase 0.0011 0.0007 0.0013
Trypanosoma cruzi GTP-binding nuclear protein rtb2, putative 0.0026 0.009 0.135
Echinococcus multilocularis Polycystic kidney disease protein 0.0042 0.0188 0.0182
Schistosoma mansoni cpg binding protein 0.0097 0.0507 0.0967
Trichomonas vaginalis penicillin-binding protein, putative 0.004 0.0176 0.0629
Echinococcus multilocularis NADP dependent isocitrate dehydrogenase 0.0031 0.0122 0.0115
Plasmodium vivax hexose transporter 0.0336 0.1896 0.2295
Trichomonas vaginalis sugar transporter, putative 0.0047 0.0216 0.0778
Mycobacterium leprae Possible lysyl-tRNA synthetase 2 LysX 0.0075 0.0377 0.7026
Loa Loa (eye worm) hypothetical protein 0.002 0.0057 0.0085
Brugia malayi Cytochrome P450 family protein 0.0052 0.0243 0.0402
Toxoplasma gondii cell-cycle-associated protein kinase MAPK, putative 0.0543 0.31 0.5668
Plasmodium vivax hypothetical protein, conserved 0.0013 0.0015 0.001
Toxoplasma gondii calcium-dependent protein kinase CDPK2A 0.0103 0.054 0.0977
Brugia malayi major facilitator superfamily protein 0.0047 0.0216 0.0356
Mycobacterium ulcerans cytochrome P450 105Q4 Cyp105Q4 0.0014 0.0023 0.0427
Plasmodium falciparum chromodomain-helicase-DNA-binding protein 1 homolog, putative 0.0013 0.0015 0.001
Mycobacterium ulcerans cytochrome P450 150A6 Cyp150A6 0.0014 0.0023 0.0427
Loa Loa (eye worm) hypothetical protein 0.0187 0.1029 0.1741
Echinococcus multilocularis lysine specific demethylase 5A 0.0035 0.0146 0.014
Trichomonas vaginalis sugar transporter, putative 0.0047 0.0216 0.0778
Echinococcus multilocularis Chromo domain 0.0013 0.0015 0.0009
Plasmodium falciparum proline--tRNA ligase 0.0117 0.0625 0.0751
Trypanosoma cruzi glycyl-tRNA synthetase, putative 0.0011 0.0007 0.0005
Plasmodium falciparum importin beta, putative 0.0035 0.0144 0.0166
Schistosoma mansoni tar DNA-binding protein 0.0065 0.0321 0.0611
Loa Loa (eye worm) hypothetical protein 0.0047 0.0216 0.0356
Brugia malayi hypothetical protein 0.0047 0.0216 0.0356
Echinococcus granulosus muscleblind protein 0.018 0.0991 0.188
Plasmodium vivax mitogen-activated protein kinase 2, putative 0.0543 0.31 0.3758
Brugia malayi Bromodomain containing protein 0.0033 0.0132 0.0214
Onchocerca volvulus 0.0047 0.0216 0.0749
Entamoeba histolytica DNA (cytosine-5)-methyltransferase, putative 0.002 0.0055 0.0248
Echinococcus granulosus Chromo domain 0.0013 0.0015 0.0017
Echinococcus granulosus synaptic vesicle 2 protein 0.0047 0.0216 0.04
Echinococcus granulosus chromodomain helicase DNA binding protein 1 0.0013 0.0015 0.0017
Trichomonas vaginalis ap endonuclease, putative 0.0022 0.0071 0.0238
Mycobacterium tuberculosis Probable isocitrate dehydrogenase [NADP] Icd1 (oxalosuccinate decarboxylase) (IDH) (NADP+-specific ICDH) (IDP) 0.0031 0.0122 0.0699
Echinococcus multilocularis calcium:calmodulin dependent protein kinase type 0.0103 0.054 0.0534
Schistosoma mansoni sugar transporter 0.0047 0.0216 0.0412
Plasmodium vivax hypothetical protein, conserved 0.0029 0.011 0.0126
Echinococcus multilocularis lysyl tRNA synthetase 0.0075 0.0377 0.0371
Schistosoma mansoni aspartyl-tRNA synthetase 0.0011 0.0007 0.0013
Trypanosoma brucei glucose transporter, putative 0.0104 0.0547 0.8748
Entamoeba histolytica chromodomain-helicase-DNA-binding protein, putative 0.0013 0.0015 0.0044
Schistosoma mansoni sugar transporter 0.0047 0.0216 0.0412
Echinococcus multilocularis isocitrate dehydrogenase 0.0031 0.0122 0.0115
Brugia malayi hypothetical protein 0.0042 0.0188 0.0309
Onchocerca volvulus 0.0047 0.0216 0.0749
Mycobacterium ulcerans cytochrome P450 108B4 Cyp108B4 0.0014 0.0023 0.0427
Leishmania major histidyl-tRNA synthetase, putative 0.0011 0.0007 0.0005
Entamoeba histolytica protein kinase, putative 0.0103 0.054 0.273
Trichomonas vaginalis sugar transporter, putative 0.0104 0.0547 0.2012
Entamoeba histolytica acetyltransferase, GNAT family 0.0042 0.0183 0.0904
Echinococcus granulosus calcium:calmodulin dependent protein kinase type 1 0.0103 0.054 0.1018
Toxoplasma gondii target of rapamycin (TOR), putative 0.0018 0.0046 0.0071
Trypanosoma brucei glucose transporter, putative 0.0104 0.0547 0.8748
Entamoeba histolytica glycyl-tRNA synthetase, putative 0.0019 0.0051 0.0226
Plasmodium falciparum calcium-dependent protein kinase 1 0.0103 0.054 0.0648
Trypanosoma brucei glucose transporter, putative 0.0104 0.0547 0.8748
Trichomonas vaginalis PIKK family atypical protein kinase 0.0018 0.0046 0.0145
Plasmodium vivax hypothetical protein, conserved 0.004 0.0176 0.0205
Brugia malayi hypothetical protein 0.002 0.0055 0.0083
Trichomonas vaginalis chromodomain helicase DNA binding protein, putative 0.0027 0.01 0.0346
Leishmania major prolyl-tRNA synthetase, putative,bifunctional aminoacyl-tRNA synthetase, putative 0.0117 0.0625 1
Trypanosoma brucei Lanosterol 14-alpha demethylase 0.0014 0.0023 0.0257
Schistosoma mansoni chromobox protein-related (chromobox 1) (heterochromatin 1) 0.0013 0.0015 0.0029
Trichomonas vaginalis chromodomain-helicase-DNA-binding protein, putative 0.0013 0.0015 0.0032
Loa Loa (eye worm) hypothetical protein 0.0047 0.0216 0.0356
Trichomonas vaginalis sugar transporter, putative 0.0047 0.0216 0.0778
Loa Loa (eye worm) hypothetical protein 0.003 0.0118 0.019
Entamoeba histolytica FKBP-rapamycin associated protein (FRAP), putative 0.0018 0.0046 0.0199
Echinococcus multilocularis Chromobox protein 3 0.0013 0.0015 0.0009
Mycobacterium leprae Probable threonyl-tRNA synthetase ThrS (threonine-tRNA synthetase) (ThrRS) (Threonine-tRNA ligase) 0.0019 0.0051 0.0562
Trypanosoma brucei glucose transporter, putative 0.0104 0.0547 0.8748
Trichomonas vaginalis sugar transporter, putative 0.0047 0.0216 0.0778
Trypanosoma brucei aspartyl-tRNA synthetase, putative 0.0011 0.0007 0.0001
Trichomonas vaginalis bromodomain-containing protein, putative 0.0045 0.0205 0.0738
Loa Loa (eye worm) bifunctional aminoacyl-tRNA synthetase 0.0041 0.0182 0.0298
Brugia malayi jmjC domain containing protein 0.0095 0.0495 0.0832
Trichomonas vaginalis conserved hypothetical protein 0.0013 0.0015 0.0032
Schistosoma mansoni lysyl-tRNA synthetase 0.0075 0.0377 0.0719
Echinococcus granulosus calcium:calmodulin dependent protein kinase type 0.0103 0.054 0.1018
Plasmodium vivax calcium-dependent protein kinase, putative 0.0103 0.054 0.0648
Mycobacterium ulcerans lysyl-tRNA synthetase 0.0075 0.0377 1
Toxoplasma gondii C-5 cytosine-specific DNA methylase superfamily protein 0.002 0.0055 0.0089
Echinococcus multilocularis disco interacting protein 2 0.0039 0.017 0.0164
Schistosoma mansoni Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) 0.0144 0.0781 0.149
Trypanosoma cruzi threonyl-tRNA synthetase, putative 0.0019 0.0051 0.0715
Mycobacterium ulcerans histidyl-tRNA synthetase 0.0011 0.0007 0.0008
Onchocerca volvulus 0.0034 0.0141 0.0468
Plasmodium falciparum isocitrate dehydrogenase [NADP], mitochondrial 0.0031 0.0122 0.014
Trichomonas vaginalis chromodomain helicase DNA binding protein, putative 0.0019 0.0054 0.0178
Toxoplasma gondii isocitrate dehydrogenase 0.0031 0.0122 0.0211
Trichomonas vaginalis sugar transporter, putative 0.0047 0.0216 0.0778
Trichomonas vaginalis sugar transporter, putative 0.0047 0.0216 0.0778
Leishmania major hypothetical protein, conserved 0.0017 0.0038 0.0508
Trichomonas vaginalis conserved hypothetical protein 0.0013 0.0015 0.0032
Brugia malayi Sugar transporter family protein 0.0336 0.1896 0.3219
Brugia malayi PHD-finger family protein 0.0029 0.011 0.0176
Trypanosoma cruzi hypothetical protein, conserved 0.004 0.0176 0.2735
Onchocerca volvulus Alhambra homolog 0.0029 0.011 0.0354
Brugia malayi Sugar transporter family protein 0.0047 0.0216 0.0356
Leishmania major hypothetical protein, conserved 0.0017 0.0038 0.0508
Entamoeba histolytica hypothetical protein 0.0013 0.0015 0.0044
Mycobacterium tuberculosis Conserved protein 0.004 0.0176 0.108
Toxoplasma gondii histone lysine acetyltransferase GCN5-A 0.0045 0.0205 0.0364
Onchocerca volvulus 0.0042 0.0188 0.0645
Onchocerca volvulus 0.0038 0.0164 0.0554
Trypanosoma brucei cytosine-specific DNA methylase, putative 0.002 0.0055 0.0785
Loa Loa (eye worm) hypothetical protein 0.0047 0.0216 0.0356
Mycobacterium ulcerans cytochrome P450 123A3 Cyp123A3 0.0014 0.0023 0.0427
Echinococcus granulosus 5'partial|histone lysine N methyltransferase SETDB2 0.0057 0.0274 0.0511
Giardia lamblia GTP-binding nuclear protein RAN/TC4 0.0026 0.009 0.0428
Mycobacterium ulcerans integral membrane transport protein 0.0047 0.0216 0.5643
Leishmania major peptidyl-prolyl cis-trans isomerase, putative 0.0012 0.0012 0.0091
Schistosoma mansoni family S12 unassigned peptidase (S12 family) 0.004 0.0176 0.0335
Echinococcus granulosus Chromobox protein 3 0.0013 0.0015 0.0017
Echinococcus granulosus NADP dependent isocitrate dehydrogenase 0.0031 0.0122 0.022
Plasmodium vivax SET domain protein, putative 0.0061 0.0295 0.035
Echinococcus granulosus lysyl tRNA synthetase 0.0075 0.0377 0.0708
Trypanosoma brucei isocitrate dehydrogenase [NADP], mitochondrial precursor, putative 0.0031 0.0122 0.186
Leishmania major glucose transporter, lmgt3 0.0104 0.0547 0.8747
Brugia malayi Latrophilin receptor protein 2 0.0086 0.0444 0.0746
Mycobacterium tuberculosis Probable esterase LipL 0.004 0.0176 0.108
Schistosoma mansoni DNA (cytosine-5)-methyltransferase 0.002 0.0055 0.0105
Loa Loa (eye worm) cytochrome P450 family protein 0.0052 0.0243 0.0402
Schistosoma mansoni rab6-interacting 0.0042 0.0188 0.0359
Trypanosoma cruzi PAB1-binding protein , putative 0.003 0.0118 0.1804
Trichomonas vaginalis sugar transporter, putative 0.0047 0.0216 0.0778
Trypanosoma cruzi target of rapamycin kinase 3 0.0018 0.0046 0.0628
Loa Loa (eye worm) CYP4Cod1 0.0014 0.0023 0.0027
Brugia malayi latrophilin 2 splice variant baaae 0.0187 0.1029 0.1741
Brugia malayi calcium-independent alpha-latrotoxin receptor 2, putative 0.0086 0.0444 0.0746
Echinococcus granulosus chromobox protein 1 0.0078 0.0395 0.0742
Loa Loa (eye worm) hypothetical protein 0.004 0.0176 0.0288
Trypanosoma brucei glycyl-tRNA synthetase, putative 0.0019 0.0051 0.0716
Echinococcus granulosus calcium:calmodulin dependent protein kinase type 0.0103 0.054 0.1018
Brugia malayi Calcium/calmodulin-dependent protein kinase type II alpha chain 0.0103 0.054 0.0908
Echinococcus granulosus solute carrier family 2 facilitated glucose 0.0336 0.1896 0.3607
Trichomonas vaginalis PIKK family atypical protein kinase 0.0018 0.0046 0.0145
Trichomonas vaginalis conserved hypothetical protein 0.0031 0.0121 0.0426
Echinococcus granulosus calcium dependent protein kinase 0.0096 0.0503 0.0947
Echinococcus multilocularis solute carrier family 22 0.0047 0.0216 0.021
Trypanosoma cruzi hexose transporter, putative 0.0104 0.0547 0.8747
Echinococcus multilocularis survival motor neuron protein 1 0.027 0.1511 0.1506
Trypanosoma brucei threonyl-tRNA synthetase, putative 0.0019 0.0051 0.0716
Loa Loa (eye worm) phosphatidylinositol 3 0.0018 0.0046 0.0066
Schistosoma mansoni jumonji/arid domain-containing protein 0.0039 0.0167 0.0318
Trichomonas vaginalis chromodomain-helicase-DNA-binding protein, putative 0.0027 0.01 0.0346
Toxoplasma gondii GTP-binding nuclear protein ran/tc4 0.0026 0.009 0.0153
Loa Loa (eye worm) PHD-finger family protein 0.0029 0.011 0.0176
Loa Loa (eye worm) Pin1-type peptidyl-prolyl cis-trans isomerase 0.004 0.0176 0.0288
Trichomonas vaginalis conserved hypothetical protein 0.0013 0.0015 0.0032
Brugia malayi major facilitator superfamily protein 0.0047 0.0216 0.0356
Onchocerca volvulus 0.0047 0.0216 0.0749
Trichomonas vaginalis chromobox protein, putative 0.0078 0.0395 0.1446
Onchocerca volvulus 0.0047 0.0216 0.0749
Loa Loa (eye worm) TAR-binding protein 0.0065 0.0321 0.0535
Plasmodium vivax calcium-dependent protein kinase 3, putative 0.0103 0.054 0.0648
Entamoeba histolytica histidyl-tRNA synthetase, putative 0.0011 0.0007 0.0001
Loa Loa (eye worm) beta-LACTamase domain containing family member 0.004 0.0176 0.0288
Toxoplasma gondii histone lysine methyltransferase SET/SUV39 0.0061 0.0295 0.0528
Echinococcus granulosus Sugar transporter ERD6 protein 0.0047 0.0216 0.04
Trichomonas vaginalis penicillin-binding protein, putative 0.004 0.0176 0.0629
Loa Loa (eye worm) hypothetical protein 0.0042 0.0188 0.0309
Onchocerca volvulus 0.0053 0.0248 0.0867
Toxoplasma gondii exonuclease III APE 0.0022 0.0071 0.0117
Brugia malayi acetyltransferase, GNAT family protein 0.0154 0.0839 0.1418
Echinococcus multilocularis mixed lineage leukemia protein mll 0.0018 0.0046 0.004
Toxoplasma gondii sugar transporter ST1 0.0047 0.0216 0.0383
Trichomonas vaginalis conserved hypothetical protein 0.0031 0.0121 0.0426
Mycobacterium ulcerans fatty-acid-CoA ligase 0.002 0.0057 0.1342
Plasmodium falciparum GTP-binding nuclear protein RAN/TC4 0.0026 0.009 0.0101
Mycobacterium tuberculosis Probable fatty-acid-CoA ligase FadD2 (fatty-acid-CoA synthetase) (fatty-acid-CoA synthase) 0.0027 0.0096 0.0515
Echinococcus multilocularis histone lysine N methyltransferase MLL3 0.0022 0.0069 0.0063
Trichomonas vaginalis sugar transporter, putative 0.0047 0.0216 0.0778
Loa Loa (eye worm) follicle stimulating hormone receptor 0.1019 0.5876 1
Loa Loa (eye worm) pigment dispersing factor receptor c 0.0273 0.1532 0.2598
Loa Loa (eye worm) CHromoDomain protein family member 0.0016 0.0037 0.0051
Trypanosoma cruzi cytochrome P450, putative 0.0014 0.0023 0.0256
Echinococcus multilocularis chromobox protein 1 0.0078 0.0395 0.0389
Loa Loa (eye worm) hypothetical protein 0.0035 0.0144 0.0233
Brugia malayi AMP-binding enzyme family protein 0.0027 0.0096 0.0151
Loa Loa (eye worm) hypothetical protein 0.0103 0.054 0.0908
Mycobacterium ulcerans cytochrome P450 142A3 Cyp142A3 0.0014 0.0023 0.0427
Echinococcus granulosus peregrin 0.0033 0.0132 0.024
Mycobacterium tuberculosis Lysyl-tRNA synthetase 2 LysX 0.0064 0.0312 0.2038
Trypanosoma cruzi histidyl-tRNA synthetase 0.0011 0.0007 0.0005
Trypanosoma brucei phosphatidylinositol 3-kinase, putative 0.0018 0.0046 0.0629
Schistosoma mansoni gcn5proteinral control of amino-acid synthesis 5-like 2 gcnl2 0.0154 0.0839 0.16
Loa Loa (eye worm) hypothetical protein 0.0047 0.0216 0.0356
Echinococcus granulosus expressed protein 0.004 0.0176 0.0324
Mycobacterium leprae Probable prolyl tRNA synthetase ProS 0.0101 0.0528 1
Schistosoma mansoni chromobox protein 0.0013 0.0015 0.0029
Trichomonas vaginalis sugar transporter, putative 0.0047 0.0216 0.0778
Leishmania major 4-coumarate:coa ligase-like protein 0.0027 0.0096 0.1437
Schistosoma mansoni histidyl-tRNA synthetase 0.0011 0.0007 0.0013
Echinococcus multilocularis isocitrate dehydrogenase 2 (NADP+) 0.0031 0.0122 0.0115
Loa Loa (eye worm) jmjC domain-containing protein 0.006 0.029 0.0483
Schistosoma mansoni hypothetical protein 0.0336 0.1896 0.3614
Toxoplasma gondii cytochrome p450 superfamily protein 0.0014 0.0023 0.0029
Echinococcus granulosus cpg binding protein 0.0101 0.0528 0.0997
Loa Loa (eye worm) hypothetical protein 0.0047 0.0216 0.0356
Brugia malayi hypothetical protein 0.0042 0.0188 0.0309
Wolbachia endosymbiont of Brugia malayi prolyl-tRNA synthetase 0.0019 0.0051 0.2114
Plasmodium falciparum heterochromatin protein 1 0.0013 0.0015 0.001
Plasmodium falciparum calcium-dependent protein kinase 2 0.0103 0.054 0.0648
Trichomonas vaginalis PIKK family atypical protein kinase 0.0018 0.0046 0.0145
Echinococcus multilocularis arachidonate 5 lipoxygenase 0.0254 0.1419 0.1414
Trichomonas vaginalis conserved hypothetical protein 0.0021 0.0061 0.0201
Trypanosoma brucei histidyl-tRNA synthetase 0.0011 0.0007 0.0005
Plasmodium falciparum ataxin-2 like protein, putative 0.003 0.0118 0.0135
Schistosoma mansoni aspartyl-tRNA synthetase 0.0011 0.0007 0.0013
Loa Loa (eye worm) hypothetical protein 0.0013 0.0015 0.0015
Trichomonas vaginalis conserved hypothetical protein 0.0336 0.1896 0.703
Trichomonas vaginalis conserved hypothetical protein 0.0044 0.0196 0.0703
Leishmania major glucose transporter, lmgt1 0.0104 0.0547 0.8747
Mycobacterium ulcerans cytochrome P450 144A4 Cyp144A4 0.0014 0.0023 0.0427
Schistosoma mansoni rotamase 0.004 0.0176 0.0335
Schistosoma mansoni glycyl-tRNA synthetase 0.0019 0.0051 0.0097
Echinococcus multilocularis PHD finger protein rhinoceros 0.0029 0.011 0.0104
Schistosoma mansoni cpg binding protein 0.0101 0.0528 0.1007
Schistosoma mansoni hypothetical protein 0.0749 0.4301 0.82
Leishmania major cytochrome p450-like protein 0.0014 0.0023 0.0256
Trypanosoma cruzi cytochrome P450, putative 0.0014 0.0023 0.0256
Toxoplasma gondii protein kinase, putative 0.0949 0.5465 1
Onchocerca volvulus 0.0047 0.0216 0.0749
Mycobacterium tuberculosis Conserved hypothetical protein 0.0017 0.0038 0.011
Trypanosoma cruzi prolyl-tRNA synthetase, putative 0.0117 0.0625 1
Echinococcus multilocularis calcium dependent protein kinase 0.0096 0.0503 0.0497
Echinococcus multilocularis Threonyl tRNA synthetase, C 0.0019 0.0051 0.0045
Brugia malayi Major Facilitator Superfamily protein 0.0047 0.0216 0.0356
Brugia malayi Major Facilitator Superfamily protein 0.0047 0.0216 0.0356
Echinococcus granulosus lysine specific demethylase 5A 0.0039 0.0167 0.0307
Brugia malayi hypothetical protein 0.003 0.0118 0.019
Loa Loa (eye worm) hypothetical protein 0.0047 0.0216 0.0356
Toxoplasma gondii hypothetical protein 0.0084 0.043 0.0776
Trichomonas vaginalis sugar transporter, putative 0.0047 0.0216 0.0778
Trypanosoma brucei importin beta-1 subunit, putative 0.0035 0.0144 0.2217
Trichomonas vaginalis sugar transporter, putative 0.0047 0.0216 0.0778
Plasmodium vivax calcium-dependent protein kinase 4, putative 0.0103 0.054 0.0648
Trichomonas vaginalis conserved hypothetical protein 0.0017 0.0038 0.0117
Onchocerca volvulus 0.0047 0.0216 0.0749
Loa Loa (eye worm) hypothetical protein 0.0082 0.0418 0.07
Trichomonas vaginalis sugar transporter, putative 0.0047 0.0216 0.0778
Echinococcus granulosus histone lysine N methyltransferase MLL3 0.0022 0.0069 0.0119
Trichomonas vaginalis PIKK family atypical protein kinase 0.0018 0.0046 0.0145
Trichomonas vaginalis Importin beta-1 subunit, putative 0.0028 0.0105 0.0367
Onchocerca volvulus 0.0047 0.0216 0.0749
Giardia lamblia Endonuclease/Exonuclease/phosphatase 0.0022 0.0071 0.0328
Brugia malayi Valyl-tRNA synthetase 0.0013 0.0015 0.0015
Brugia malayi Phosphatidylinositol 3- and 4-kinase family protein 0.0018 0.0046 0.0066
Echinococcus multilocularis gcn5proteinral control of amino acid synthesis 0.0154 0.0839 0.0833
Trichomonas vaginalis D-aminoacylase, putative 0.004 0.0176 0.0629
Echinococcus granulosus solute carrier family 22 0.0047 0.0216 0.04
Trypanosoma cruzi phosphatidylinositol kinase related protein, putative 0.0021 0.0065 0.0935
Toxoplasma gondii PHD-finger domain-containing protein 0.0029 0.011 0.019
Echinococcus multilocularis DNA methyltransferase 2, putative 0.002 0.0055 0.0049
Trichomonas vaginalis chromodomain-helicase-DNA-binding protein, putative 0.0013 0.0015 0.0032
Chlamydia trachomatis proline--tRNA ligase 0.0036 0.0148 0.3815
Echinococcus multilocularis solute carrier family 22 0.0047 0.0216 0.021
Leishmania major phosphatidylinositol kinase related protein, putative 0.0018 0.0046 0.0632
Loa Loa (eye worm) hypothetical protein 0.002 0.0057 0.0085
Brugia malayi GTP-binding regulatory protein Gs alpha-S chain, putative 0.0144 0.0781 0.132
Trichomonas vaginalis sugar transporter, putative 0.0047 0.0216 0.0778
Mycobacterium tuberculosis Probable lipase LipD 0.004 0.0176 0.108
Brugia malayi AMP-binding enzyme family protein 0.0027 0.0096 0.0151
Loa Loa (eye worm) histone methyltransferase 0.0022 0.0069 0.0106
Echinococcus multilocularis lipoxygenase domain containing protein 0.0042 0.0188 0.0182
Schistosoma mansoni hypothetical protein 0.0013 0.0015 0.0029
Echinococcus multilocularis expressed protein 0.004 0.0176 0.017
Trypanosoma brucei peptidyl-prolyl cis-trans isomerase, putative 0.0012 0.0012 0.0092
Trypanosoma cruzi peptidyl-prolyl cis-trans isomerase, putative 0.0012 0.0012 0.0091
Toxoplasma gondii calcium-dependent protein kinase CDPK3 0.0103 0.054 0.0977
Brugia malayi F/Y-rich N-terminus family protein 0.0031 0.0123 0.0198
Trypanosoma cruzi peptidyl-prolyl cis-trans isomerase 0.0039 0.017 0.2647
Onchocerca volvulus 0.0042 0.0188 0.0645
Trichomonas vaginalis PIKK family atypical protein kinase 0.0018 0.0046 0.0145
Schistosoma mansoni hypothetical protein 0.0014 0.002 0.0039
Trichomonas vaginalis conserved hypothetical protein 0.0044 0.0196 0.0703
Echinococcus granulosus RUN 0.0042 0.0188 0.0347
Giardia lamblia PHD finger protein 15 0.0029 0.011 0.053
Trichomonas vaginalis chromodomain-helicase-DNA-binding protein, putative 0.0021 0.0061 0.0201
Loa Loa (eye worm) heterochromatin protein 1 0.0078 0.0395 0.0662
Echinococcus multilocularis GTP binding nuclear protein Ran 0.0026 0.009 0.0084
Trichomonas vaginalis sugar transporter, putative 0.0047 0.0216 0.0778
Wolbachia endosymbiont of Brugia malayi parvulin-like peptidyl-prolyl isomerase, PPID 0.0012 0.0012 0.027
Brugia malayi bifunctional aminoacyl-tRNA synthetase 0.0101 0.0528 0.0887
Mycobacterium ulcerans long-chain-fatty-acid--CoA ligase 0.0027 0.0096 0.2396
Loa Loa (eye worm) CXXC zinc finger family protein 0.0097 0.0507 0.0853
Schistosoma mansoni survival motor neuron protein 0.0055 0.0261 0.0498
Leishmania major GTP-binding protein, putative 0.0026 0.009 0.135
Entamoeba histolytica prolyl-tRNA synthetase, putative 0.0101 0.0528 0.2668
Brugia malayi Isocitrate dehydrogenase 0.0031 0.0122 0.0196
Onchocerca volvulus 0.0047 0.0216 0.0749
Schistosoma mansoni phosphatidylinositol 3-and 4-kinase 0.0018 0.0046 0.0087
Loa Loa (eye worm) MH2 domain-containing protein 0.0139 0.0749 0.1265
Echinococcus granulosus PHD finger protein rhinoceros 0.0029 0.011 0.0198
Brugia malayi probable proline-trna synthetase - fission yeast, putative 0.0019 0.0051 0.0075
Trichomonas vaginalis PIKK family atypical protein kinase 0.0025 0.0085 0.029
Plasmodium falciparum DNA (cytosine-5)-methyltransferase 0.002 0.0055 0.0059
Treponema pallidum threonyl-tRNA synthetase 0.0019 0.0051 0.3127
Echinococcus multilocularis chromobox protein 1 0.0078 0.0395 0.0389
Echinococcus multilocularis chromobox protein 2 0.0013 0.0015 0.0009
Toxoplasma gondii prolyl-tRNA synthetase (ProRS) 0.0117 0.0625 0.1132
Echinococcus granulosus mixed lineage leukemia protein mll 0.0018 0.0046 0.0076
Echinococcus multilocularis beta LACTamase domain containing family member 0.004 0.0176 0.017
Trichomonas vaginalis lysyl-tRNA synthetase, putative 0.0075 0.0377 0.1379
Schistosoma mansoni cpg binding protein 0.0101 0.0528 0.1007
Trypanosoma brucei aspartyl-tRNA synthetase, putative 0.0011 0.0007 0.0001
Mycobacterium ulcerans cytochrome P450 140A5 Cyp140A5 0.0014 0.0023 0.0427
Schistosoma mansoni chromodomain helicase DNA binding protein 0.0013 0.0015 0.0029
Schistosoma mansoni mixed-lineage leukemia protein mll 0.0028 0.0102 0.0194
Echinococcus multilocularis muscleblind protein 0.018 0.0991 0.0986
Schistosoma mansoni ataxia telangiectasia mutated (atm) 0.0025 0.0085 0.0161
Schistosoma mansoni loxhd1 0.0042 0.0188 0.0359
Echinococcus granulosus calcium:calmodulin dependent protein kinase type 0.0103 0.054 0.1018
Trichomonas vaginalis sugar transporter, putative 0.0047 0.0216 0.0778
Echinococcus granulosus DNA methyltransferase 2, putative 0.002 0.0055 0.0093
Plasmodium vivax hypothetical protein, conserved 0.0013 0.0015 0.001
Echinococcus multilocularis synaptic vesicle 2 protein 0.0047 0.0216 0.021
Mycobacterium ulcerans lysyl-tRNA synthetase 0.0075 0.0377 1
Plasmodium vivax threonine--tRNA ligase, putative 0.0019 0.0051 0.0054
Brugia malayi hypothetical protein 0.0047 0.0216 0.0356
Entamoeba histolytica hypothetical protein 0.0028 0.0105 0.0505
Toxoplasma gondii calcium-dependent protein kinase CDPK2B 0.0103 0.054 0.0977
Brugia malayi Cytochrome P450 family protein 0.0014 0.0023 0.0027
Echinococcus granulosus Transcription factor JmjC domain containing protein 0.0095 0.0495 0.0933
Echinococcus multilocularis cadherin EGF LAG seven pass G type receptor 0.0086 0.0444 0.0438
Loa Loa (eye worm) hypothetical protein 0.0027 0.0096 0.0151
Echinococcus multilocularis General substrate transporter 0.0289 0.1621 0.1616
Echinococcus granulosus glutamyl tRNA synthetase cytoplasmic 0.0101 0.0528 0.0995
Trichomonas vaginalis chromobox protein, putative 0.0013 0.0015 0.0032
Trichomonas vaginalis conserved hypothetical protein 0.0017 0.0038 0.0117
Echinococcus multilocularis Ataxin 2, N terminal,domain containing protein 0.0014 0.002 0.0014
Leishmania major glucose transporter/membrane transporter D2, putative 0.0104 0.0547 0.8747
Trichomonas vaginalis helicase, putative 0.0014 0.0025 0.0069
Echinococcus multilocularis jumonji domain containing protein 0.004 0.0176 0.017
Trypanosoma cruzi Phosphatidylinositol 3-kinase tor1 0.0018 0.0046 0.0628
Trypanosoma brucei ULK family serine/threonine-protein kinase, putative 0.0013 0.0017 0.0162
Echinococcus granulosus Jumonji AT rich interactive domain 1B 0.0013 0.0017 0.002
Wolbachia endosymbiont of Brugia malayi histidyl-tRNA synthetase 0.0011 0.0007 0.0014
Schistosoma mansoni chromodomain helicase DNA binding protein 0.0016 0.0037 0.007
Trichomonas vaginalis Importin beta-1 subunit, putative 0.0028 0.0105 0.0367
Toxoplasma gondii sugar transporter ST3 0.0047 0.0216 0.0383
Leishmania major 4-coumarate:coa ligase-like protein 0.0027 0.0096 0.1437
Brugia malayi RNA binding protein 0.0065 0.0321 0.0535
Loa Loa (eye worm) hypothetical protein 0.004 0.0176 0.0288
Schistosoma mansoni histone-lysine n-methyltransferase setb1 0.0061 0.0295 0.0563
Schistosoma mansoni tar DNA-binding protein 0.0065 0.0321 0.0611
Loa Loa (eye worm) sugar transporter 0.0047 0.0216 0.0356
Schistosoma mansoni mixed-lineage leukemia protein mll 0.0011 0.0007 0.0014
Schistosoma mansoni ataxia telangiectasia mutated (atm)-related 0.0018 0.0046 0.0087
Echinococcus granulosus GPCR family 2 0.0086 0.0444 0.0836
Loa Loa (eye worm) hypothetical protein 0.0029 0.011 0.0176
Echinococcus multilocularis tumor protein p63 0.036 0.2035 0.203
Trichomonas vaginalis conserved hypothetical protein 0.0047 0.0216 0.0778
Echinococcus multilocularis phosphatidylinositol 3 and 4 kinase 0.0018 0.0046 0.0039
Echinococcus multilocularis cpg binding protein 0.0101 0.0528 0.0522
Echinococcus granulosus aspartyl tRNA synthetase cytoplasmic 0.0011 0.0007 0.0001
Mycobacterium tuberculosis Conserved protein 0.004 0.0176 0.108
Plasmodium falciparum protein kinase 6 0.1425 0.8238 1
Onchocerca volvulus 0.0047 0.0216 0.0749
Trichomonas vaginalis cat eye syndrome critical region protein 2, cscr2, putative 0.0045 0.0205 0.0738
Leishmania major lysyl-tRNA synthetase, putative 0.0075 0.0377 0.5997
Schistosoma mansoni hypothetical protein 0.0749 0.4301 0.82
Mycobacterium tuberculosis Probable fatty-acid-CoA ligase FadD35 (fatty-acid-CoA synthetase) (fatty-acid-CoA synthase) 0.0019 0.005 0.0195
Treponema pallidum prolyl-tRNA synthetase 0.0036 0.0148 1
Mycobacterium leprae Probable lipase LipE 0.004 0.0176 0.3034
Onchocerca volvulus 0.0074 0.0369 0.1322
Entamoeba histolytica Rad52/22 family double-strand break repair protein, putative 0.0099 0.0515 0.2604
Mycobacterium leprae PROBABLE FATTY-ACID-CoA LIGASE FADD2 (FATTY-ACID-CoA SYNTHETASE) (FATTY-ACID-CoA SYNTHASE) 0.0027 0.0096 0.1446
Plasmodium falciparum mitogen-activated protein kinase 2 0.0543 0.31 0.3758
Echinococcus multilocularis solute carrier family 22 0.0047 0.0216 0.021
Toxoplasma gondii anticodon binding domain-containing protein 0.0011 0.0007 0.0001
Trichomonas vaginalis sugar transporter, putative 0.0047 0.0216 0.0778
Toxoplasma gondii transporter, major facilitator family protein 0.0047 0.0216 0.0383
Mycobacterium tuberculosis Fatty-acid-AMP ligase FadD30 (fatty-acid-AMP synthetase) (fatty-acid-AMP synthase) 0.002 0.0057 0.0239
Entamoeba histolytica hypothetical protein 0.0025 0.0085 0.0399
Mycobacterium ulcerans glycyl-tRNA synthetase 0.0019 0.0051 0.1193
Mycobacterium tuberculosis Probable fatty-acid-CoA ligase FadD5 (fatty-acid-CoA synthetase) (fatty-acid-CoA synthase) 0.0019 0.005 0.0195
Loa Loa (eye worm) aspartyl-tRNA synthetase 0.0011 0.0007 0.0000066056
Echinococcus granulosus histone acetyltransferase KAT2B 0.015 0.0814 0.1542
Loa Loa (eye worm) hypothetical protein 0.0013 0.0015 0.0015
Mycobacterium ulcerans lipase LipD 0.004 0.0176 0.456
Plasmodium vivax AP endonuclease (DNA-[apurinic or apyrimidinic site] lyase), putative 0.0022 0.0071 0.0078
Loa Loa (eye worm) hypothetical protein 0.0042 0.0188 0.0309
Brugia malayi Cam kinase protein 1 0.0103 0.054 0.0908
Brugia malayi glycyl-tRNA synthetase 0.0019 0.0051 0.0075
Loa Loa (eye worm) hypothetical protein 0.0013 0.0015 0.0015
Leishmania major glycyl tRNA synthetase, putative 0.0011 0.0007 0.0005
Trichomonas vaginalis PIKK family atypical protein kinase 0.0018 0.0046 0.0145
Onchocerca volvulus 0.0047 0.0216 0.0749
Schistosoma mansoni aspartyl-tRNA synthetase 0.0011 0.0007 0.0013
Schistosoma mansoni protein kinase 0.0103 0.054 0.1029
Mycobacterium ulcerans cytochrome P450 185A4 Cyp185A4 0.0014 0.0023 0.0427
Schistosoma mansoni rab6-interacting 0.0042 0.0188 0.0359
Plasmodium falciparum lysine--tRNA ligase 0.0075 0.0377 0.045
Trypanosoma brucei lysyl-tRNA synthetase, putative 0.0075 0.0377 0.5998
Brugia malayi Sugar transporter family protein 0.0047 0.0216 0.0356
Trichomonas vaginalis conserved hypothetical protein 0.0014 0.0025 0.0069
Trypanosoma cruzi apurinic/apyrimidinic endonuclease 0.0022 0.0071 0.1035
Leishmania major 4-coumarate:coa ligase-like protein 0.0027 0.0096 0.1437
Brugia malayi RNA recognition motif domain containing protein 0.0065 0.0321 0.0535
Trypanosoma cruzi Phosphatidylinositol 3-kinase tor2 0.0018 0.0046 0.0628
Loa Loa (eye worm) cytochrome P450 family protein 0.0014 0.0023 0.0027
Brugia malayi exodeoxyribonuclease III family protein 0.0022 0.0071 0.0109
Trichomonas vaginalis ran, putative 0.0026 0.009 0.0311
Schistosoma mansoni hypothetical protein 0.0911 0.5246 1
Loa Loa (eye worm) sugar transporter 0.0336 0.1896 0.3219
Trypanosoma brucei hypothetical protein, conserved 0.004 0.0176 0.2735
Trichomonas vaginalis sugar transporter, putative 0.0047 0.0216 0.0778
Trypanosoma cruzi GTP-binding nuclear protein rtb2, putative 0.0026 0.009 0.135
Trichomonas vaginalis conserved hypothetical protein 0.0047 0.0216 0.0778
Leishmania major lanosterol 14-alpha-demethylase, putative 0.0014 0.0023 0.0256
Loa Loa (eye worm) hypothetical protein 0.0013 0.0018 0.0018
Loa Loa (eye worm) hypothetical protein 0.0019 0.0051 0.0075
Trypanosoma cruzi hypothetical protein, conserved 0.004 0.0176 0.2735
Onchocerca volvulus Putative transporter 0.0047 0.0216 0.0749
Trichomonas vaginalis PIKK family atypical protein kinase 0.0018 0.0046 0.0145
Loa Loa (eye worm) hypothetical protein 0.0047 0.0216 0.0356
Trypanosoma brucei lysyl-tRNA synthetase, putative 0.0011 0.0007 0.0001
Trichomonas vaginalis chromodomain helicase DNA binding protein, putative 0.0027 0.01 0.0346
Plasmodium vivax ataxin-2 like protein, putative 0.003 0.0118 0.0135
Loa Loa (eye worm) hypothetical protein 0.0047 0.0216 0.0356
Schistosoma mansoni sugar transporter 0.0047 0.0216 0.0412
Brugia malayi cytochrome P450 0.0014 0.0023 0.0027
Brugia malayi Corticotropin releasing factor receptor 2 precursor, putative 0.0273 0.1532 0.2598
Entamoeba histolytica protein kinase, putative 0.0103 0.054 0.273
Trichomonas vaginalis conserved hypothetical protein 0.0104 0.0547 0.2012
Trypanosoma cruzi phosphatidylinositol kinase related protein, putative 0.0018 0.0046 0.0632
Brugia malayi Iron-sulfur cluster assembly accessory protein 0.0055 0.0261 0.0434
Entamoeba histolytica hypothetical protein 0.0099 0.0515 0.2604
Echinococcus multilocularis DNA (apurinic or apyrimidinic site) lyase 0.0022 0.0071 0.0064
Loa Loa (eye worm) hypothetical protein 0.0013 0.0015 0.0015
Loa Loa (eye worm) hypothetical protein 0.0044 0.0196 0.0322
Brugia malayi TAR-binding protein 0.0065 0.0321 0.0535
Brugia malayi SET domain containing protein 0.0012 0.0009 0.0003
Plasmodium vivax heterochromatin protein 1, putative 0.0013 0.0015 0.001
Plasmodium falciparum conserved Plasmodium membrane protein, unknown function 0.0013 0.0019 0.0015
Echinococcus multilocularis solute carrier family 2 facilitated glucose 0.0336 0.1896 0.1891
Trichomonas vaginalis sugar transporter, putative 0.0047 0.0216 0.0778
Schistosoma mansoni hypothetical protein 0.0042 0.0188 0.0359
Plasmodium falciparum calcium-dependent protein kinase 3 0.0103 0.054 0.0648
Trypanosoma cruzi lysyl-tRNA synthetase, putative 0.0075 0.0377 0.5997
Onchocerca volvulus 0.0047 0.0216 0.0749
Schistosoma mansoni lipoxygenase 0.0177 0.0975 0.1858
Echinococcus multilocularis snurportin 1 0.0372 0.2106 0.2101
Toxoplasma gondii histidyl-tRNA synthetase (HisRS), putative 0.0011 0.0007 0.0001
Trypanosoma cruzi PAB1-binding protein , putative 0.003 0.0118 0.1804
Echinococcus granulosus guanine nucleotide binding protein Gs subunit 0.0144 0.0781 0.1479
Trichomonas vaginalis conserved hypothetical protein 0.0047 0.0216 0.0778
Plasmodium vivax GTP-binding nuclear protein RAN/TC4, putative 0.0026 0.009 0.0101
Toxoplasma gondii glycyl-tRNA synthetase 0.0019 0.0051 0.0081
Loa Loa (eye worm) major facilitator superfamily transporter 0.0047 0.0216 0.0356
Trypanosoma brucei bifunctional aminoacyl-tRNA synthetase, putative 0.0117 0.0625 1
Plasmodium vivax proline--tRNA ligase, putative 0.0117 0.0625 0.0751
Echinococcus multilocularis NADP dependent isocitrate dehydrogenase 0.0031 0.0122 0.0115
Brugia malayi GTP-binding nuclear protein RAN/TC4 0.0026 0.009 0.0142
Trichomonas vaginalis PIKK family atypical protein kinase 0.0018 0.0046 0.0145
Trichomonas vaginalis PIKK family atypical protein kinase 0.0018 0.0046 0.0145
Mycobacterium ulcerans exodeoxyribonuclease III protein XthA 0.0022 0.0071 0.1726
Onchocerca volvulus 0.004 0.0176 0.0599
Trypanosoma cruzi hexose transporter, putative 0.0104 0.0547 0.8747
Plasmodium falciparum phd finger protein, putative 0.0029 0.011 0.0126
Leishmania major cytochrome p450-like protein 0.0014 0.0023 0.0256
Schistosoma mansoni hypothetical protein 0.0187 0.1029 0.1961
Echinococcus multilocularis solute carrier family 2 facilitated glucose 0.0336 0.1896 0.1891
Loa Loa (eye worm) doublecortin family protein 0.0042 0.0188 0.0309
Trichomonas vaginalis sugar transporter, putative 0.0047 0.0216 0.0778
Mycobacterium ulcerans cytochrome P450 191A3 Cyp191A3 0.0014 0.0023 0.0427
Echinococcus granulosus histone lysine methyltransferase setb 0.0061 0.0295 0.0551
Plasmodium vivax acyl-CoA synthetase, putative 0.002 0.0057 0.006
Trichomonas vaginalis chromobox protein, putative 0.0047 0.0215 0.0775
Echinococcus multilocularis glycyl tRNA synthetase 0.0019 0.0051 0.0045
Schistosoma mansoni glucose transport protein 0.0336 0.1896 0.3614
Brugia malayi Pre-SET motif family protein 0.0061 0.0295 0.0491
Echinococcus multilocularis diuretic hormone 44 receptor GPRdih2 0.0086 0.0444 0.0438
Echinococcus multilocularis histidyl tRNA synthetase 0.0011 0.0007 0.0001
Echinococcus multilocularis FKBP12 rapamycin complex associated protein 0.0018 0.0046 0.0039
Toxoplasma gondii PPIC-type PPIASE domain-containing protein 0.0012 0.0012 0.001
Schistosoma mansoni aspartyl-tRNA synthetase 0.0011 0.0007 0.0013
Onchocerca volvulus 0.0047 0.0216 0.0749
Loa Loa (eye worm) cytochrome P450 0.0014 0.0023 0.0027
Plasmodium falciparum conserved Plasmodium protein, unknown function 0.0084 0.043 0.0515
Echinococcus granulosus chromodomain helicase DNA binding protein 4 0.0016 0.0037 0.0058
Echinococcus multilocularis dnaJ subfamily B 0.0911 0.5246 0.5243
Echinococcus granulosus glycyl tRNA synthetase 0.0019 0.0051 0.0085
Plasmodium vivax CDK-related protein kinase 6, putative 0.1425 0.8238 1
Echinococcus granulosus General substrate transporter 0.0289 0.1621 0.3082
Brugia malayi hypothetical protein 0.027 0.1511 0.2563
Plasmodium falciparum hexose transporter 0.0336 0.1896 0.2295
Mycobacterium ulcerans hypothetical protein 0.004 0.0176 0.456
Trypanosoma cruzi apurinic/apyrimidinic endonuclease, putative 0.0022 0.0071 0.1035
Onchocerca volvulus 0.0027 0.0096 0.03
Mycobacterium tuberculosis Probable exodeoxyribonuclease III protein XthA (exonuclease III) (EXO III) (AP endonuclease VI) 0.0022 0.0071 0.034
Loa Loa (eye worm) hypothetical protein 0.018 0.0991 0.1678
Mycobacterium ulcerans threonyl-tRNA synthetase 0.0019 0.0051 0.1193
Trypanosoma brucei glucose transporter 2A 0.0104 0.0547 0.8748
Trichomonas vaginalis conserved hypothetical protein 0.004 0.0176 0.0629
Loa Loa (eye worm) hypothetical protein 0.0034 0.0141 0.0228
Mycobacterium tuberculosis Possible conserved lipoprotein LpqK 0.004 0.0176 0.108
Loa Loa (eye worm) hypothetical protein 0.0013 0.0015 0.0015
Echinococcus granulosus asparaginyl tRNA synthetase, cytoplasmic 0.0011 0.0007 0.0001
Leishmania major myo-inositol/proton symporter (MIT) 0.0047 0.0216 0.3384
Mycobacterium ulcerans cytochrome P450 189A7 Cyp189A7 0.0014 0.0023 0.0427
Echinococcus granulosus asparaginyl tRNA synthetase cytoplasmic 0.0011 0.0007 0.0001
Plasmodium falciparum calcium-dependent protein kinase 5 0.0103 0.054 0.0648
Trichomonas vaginalis PIKK family atypical protein kinase 0.0018 0.0046 0.0145
Trypanosoma brucei phosphatidylinositol kinase related protein, putative 0.0025 0.0085 0.1261
Entamoeba histolytica threonyl-tRNA synthetase, putative 0.0019 0.0051 0.0226
Trypanosoma cruzi isocitrate dehydrogenase [NADP], mitochondrial precursor, putative 0.0031 0.0122 0.1859
Schistosoma mansoni disco-interacting protein 2 (dip2) 0.0039 0.017 0.0324
Onchocerca volvulus Heterochromatin protein 1 homolog 0.0044 0.0196 0.0673
Mycobacterium tuberculosis Probable hydrolase 0.004 0.0176 0.108
Schistosoma mansoni serine/threonine protein kinase 0.0103 0.054 0.1029
Mycobacterium tuberculosis Probable conserved lipoprotein 0.004 0.0176 0.108
Echinococcus multilocularis muscleblind protein 1 0.018 0.0991 0.0986
Echinococcus granulosus diuretic hormone 44 receptor GPRdih2 0.0086 0.0444 0.0836
Brugia malayi lysyl-tRNA synthetase 0.0075 0.0377 0.0631
Trypanosoma cruzi Aminoacyl-tRNA editing domain containing protein, putative 0.0017 0.0038 0.0508
Plasmodium falciparum LCCL domain-containing protein 0.0042 0.0188 0.022
Leishmania major target of rapamycin kinase (TOR) kinase 3 0.0018 0.0046 0.0628
Echinococcus multilocularis calcium:calmodulin dependent protein kinase type 0.0103 0.054 0.0534
Trichomonas vaginalis conserved hypothetical protein 0.0171 0.0935 0.3456
Echinococcus multilocularis RUN 0.0042 0.0188 0.0182
Echinococcus granulosus histone acetyltransferase KAT2B 0.0045 0.0205 0.0379
Echinococcus multilocularis NADP dependent isocitrate dehydrogenase 0.0031 0.0122 0.0115
Loa Loa (eye worm) acetyltransferase 0.0154 0.0839 0.1418
Mycobacterium leprae conserved hypothetical protein 0.004 0.0176 0.3034
Echinococcus multilocularis 0.0014 0.0023 0.0016
Schistosoma mansoni chromobox protein 0.0078 0.0395 0.0754
Schistosoma mansoni jumonji/arid domain-containing protein 0.0039 0.0167 0.0318
Leishmania major protein kinase, putative 0.0103 0.054 0.8623
Mycobacterium ulcerans cytochrome P450 187A4 Cyp187A4 0.0014 0.0023 0.0427
Schistosoma mansoni histone-lysine n-methyltransferase suv9 0.0074 0.0369 0.0704
Trypanosoma brucei cytochrome P450, putative 0.0014 0.0023 0.0257
Plasmodium falciparum acyl-CoA synthetase 0.002 0.0057 0.006
Trichomonas vaginalis PIKK family atypical protein kinase 0.0018 0.0046 0.0145
Trypanosoma cruzi Lanosterol 14-alpha demethylase 0.0014 0.0023 0.0256
Toxoplasma gondii FATC domain-containing protein 0.0025 0.0085 0.0143
Trichomonas vaginalis chromobox protein, putative 0.0013 0.0015 0.0032
Trichomonas vaginalis sugar transporter, putative 0.0047 0.0216 0.0778
Plasmodium vivax importin-beta 2, putative 0.0035 0.0144 0.0166
Trichomonas vaginalis importin beta-1, putative 0.0028 0.0105 0.0367
Trichomonas vaginalis Heterochromatin protein, putative 0.0013 0.0015 0.0032
Leishmania major hypothetical protein, conserved 0.0047 0.0216 0.3384
Trichomonas vaginalis chromodomain helicase DNA binding protein, putative 0.0027 0.01 0.0346
Trichomonas vaginalis PIKK family atypical protein kinase 0.0018 0.0046 0.0145
Trichomonas vaginalis PIKK family atypical protein kinase 0.0018 0.0046 0.0145
Entamoeba histolytica acyl-coA synthetase, putative 0.0027 0.0096 0.0455
Plasmodium vivax multidomain scavenger receptor, putative 0.0042 0.0188 0.022
Echinococcus multilocularis solute carrier family 22 0.0047 0.0216 0.021
Giardia lamblia Threonyl-tRNA synthetase 0.0019 0.0051 0.0226
Loa Loa (eye worm) RNA recognition domain-containing protein domain-containing protein 0.0065 0.0321 0.0535
Toxoplasma gondii aspartate-tRNA ligase 0.0011 0.0007 0.0000071041
Giardia lamblia Glycyl-tRNA synthetase 0.0019 0.0051 0.0226
Giardia lamblia Lysyl-tRNA synthetase 0.0075 0.0377 0.1899
Loa Loa (eye worm) hypothetical protein 0.0027 0.0096 0.0151
Trichomonas vaginalis PIKK family atypical protein kinase 0.0018 0.0046 0.0145
Wolbachia endosymbiont of Brugia malayi major facilitator superfamily permease 0.0047 0.0216 1
Schistosoma mansoni family S12 unassigned peptidase (S12 family) 0.004 0.0176 0.0335
Brugia malayi RNA, U transporter 1 0.0099 0.0518 0.087
Toxoplasma gondii peptidylprolyl isomerase 0.0039 0.017 0.03
Leishmania major target of rapamycin (TOR) kinase 2, putative 0.0018 0.0046 0.0628
Giardia lamblia GTOR 0.0018 0.0046 0.0199
Trichomonas vaginalis sugar transporter, putative 0.0047 0.0216 0.0778
Echinococcus multilocularis lipoxygenase domain containing protein 0.0042 0.0188 0.0182
Trichomonas vaginalis conserved hypothetical protein 0.0104 0.0547 0.2012
Mycobacterium ulcerans cytochrome p450 150 cyp150 0.0014 0.0023 0.0427
Mycobacterium tuberculosis Probable lipase LipE 0.004 0.0176 0.108
Trypanosoma brucei Phosphatidylinositol 3-kinase tor1 0.0018 0.0046 0.0629
Trichomonas vaginalis esterase, putative 0.004 0.0176 0.0629
Schistosoma mansoni hypothetical protein 0.0086 0.0444 0.0847
Schistosoma mansoni aspartyl-tRNA synthetase 0.0011 0.0007 0.0013
Toxoplasma gondii PHD-finger domain-containing protein 0.0029 0.011 0.019
Loa Loa (eye worm) hypothetical protein 0.002 0.0057 0.0085
Schistosoma mansoni protein kinase 0.0103 0.054 0.1029
Mycobacterium ulcerans hypothetical protein 0.0017 0.0038 0.0848
Onchocerca volvulus 0.0473 0.2694 1
Schistosoma mansoni Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) 0.0144 0.0781 0.149
Mycobacterium ulcerans fusion of enoyl-CoA hydratase, EchA21 and lipase, LipE 0.004 0.0176 0.456
Trichomonas vaginalis PIKK family atypical protein kinase 0.0018 0.0046 0.0145
Leishmania major cytochrome p450-like protein 0.0014 0.0023 0.0256
Trypanosoma cruzi glucose transporter, putative 0.0047 0.0216 0.3384
Trichomonas vaginalis glucose transporter, putative 0.0047 0.0216 0.0778
Loa Loa (eye worm) hypothetical protein 0.0061 0.0295 0.0491
Loa Loa (eye worm) hypothetical protein 0.018 0.0991 0.1678
Onchocerca volvulus 0.0047 0.0216 0.0749
Plasmodium falciparum calcium-dependent protein kinase 4 0.0103 0.054 0.0648
Mycobacterium leprae Probable lysyl-tRNA synthase LysS (lysine--tRNA ligase 1) (LysRS 1) (lysine translase) 0.0064 0.0312 0.5724
Schistosoma mansoni glutamyl-tRNA synthetase cytoplasmic (glutamate--tRNA ligase) (glurs) 0.0101 0.0528 0.1006
Leishmania major importin beta-1 subunit, putative 0.0028 0.0105 0.1596
Brugia malayi beta-lactamase family protein 0.004 0.0176 0.0288
Echinococcus granulosus cytochrome P450 2K1 0.0014 0.0023 0.0031
Loa Loa (eye worm) hypothetical protein 0.0038 0.0164 0.0268
Schistosoma mansoni jumonji domain containing protein 0.0076 0.0381 0.0727
Loa Loa (eye worm) hypothetical protein 0.0086 0.0444 0.0746
Trypanosoma brucei glucose transporter, putative 0.0104 0.0547 0.8748
Echinococcus multilocularis histone lysine methyltransferase setb histone lysine methyltransferase eggless 0.0061 0.0295 0.0289
Mycobacterium tuberculosis Probable dicarboxylic acid transport integral membrane protein KgtP (dicarboxylate transporter) 0.0047 0.0216 0.1363
Loa Loa (eye worm) beta-lactamase 0.004 0.0176 0.0288
Trypanosoma brucei glucose transporter, putative 0.0104 0.0547 0.8748
Entamoeba histolytica chromodomain-helicase-DNA-binding protein, putative 0.0013 0.0015 0.0044
Trypanosoma cruzi peptidyl-prolyl cis-trans isomerase 0.0039 0.017 0.2647
Trichomonas vaginalis conserved hypothetical protein 0.0014 0.0025 0.0069
Echinococcus granulosus phosphatidylinositol 3 and 4 kinase 0.0018 0.0046 0.0075
Chlamydia trachomatis acylglycerophosphoethanolamine acyltransferase 0.002 0.0057 0.1342
Trichomonas vaginalis conserved hypothetical protein 0.0047 0.0216 0.0778
Trypanosoma brucei THT1 - hexose transporter, putative 0.0104 0.0547 0.8748
Trypanosoma cruzi Aminoacyl-tRNA editing domain containing protein, putative 0.0017 0.0038 0.0508
Schistosoma mansoni bromodomain-containing nuclear protein 1 brd1 0.0029 0.011 0.021
Brugia malayi Type III restriction enzyme, res subunit family protein 0.0013 0.0015 0.0015
Echinococcus multilocularis solute carrier family 2, facilitated glucose 0.0336 0.1896 0.1891
Mycobacterium tuberculosis Probable conserved integral membrane transport protein 0.0047 0.0216 0.1363
Echinococcus multilocularis tar DNA binding protein 0.0065 0.0321 0.0315
Echinococcus granulosus solute carrier family 2 facilitated glucose 0.0336 0.1896 0.3607
Echinococcus multilocularis Transcription factor, JmjC domain containing protein 0.0095 0.0495 0.0489
Trichomonas vaginalis lysyl-tRNA synthetase, putative 0.0066 0.0324 0.1179
Leishmania major target of rapamycin (TOR) kinase 1, putative 0.0018 0.0046 0.0628
Trypanosoma brucei glucose transporter 1E 0.0104 0.0547 0.8748
Loa Loa (eye worm) hypothetical protein 0.0176 0.0963 0.163
Trypanosoma cruzi hypothetical protein, conserved 0.0017 0.0038 0.0508
Trichomonas vaginalis D-aminoacylase, putative 0.004 0.0176 0.0629
Schistosoma mansoni glutamyl-tRNA synthetase cytoplasmic (glutamate--tRNA ligase) (glurs) 0.0101 0.0528 0.1006
Trichomonas vaginalis sugar transporter, putative 0.0047 0.0216 0.0778
Giardia lamblia Prolyl-tRNA synthetase 0.0101 0.0528 0.2668
Schistosoma mansoni histone-lysine n-methyltransferase setb1 0.0061 0.0295 0.0563
Loa Loa (eye worm) GTP-binding regulatory protein Gs alpha-S chain 0.0144 0.0781 0.132
Plasmodium vivax lysine--tRNA ligase, putative 0.0075 0.0377 0.045
Entamoeba histolytica chromodomain-helicase-DNA-binding protein, putative 0.0013 0.0015 0.0044
Trichomonas vaginalis sugar transport protein, putative 0.0047 0.0216 0.0778
Schistosoma mansoni ran 0.0026 0.009 0.0172
Loa Loa (eye worm) hypothetical protein 0.0013 0.0015 0.0015
Echinococcus granulosus snurportin 1 0.0372 0.2106 0.4007
Schistosoma mansoni aspartyl-tRNA synthetase 0.0011 0.0007 0.0013
Loa Loa (eye worm) hypothetical protein 0.0273 0.1532 0.2598
Trichomonas vaginalis PIKK family atypical protein kinase 0.0018 0.0046 0.0145
Loa Loa (eye worm) hypothetical protein 0.0075 0.0377 0.0631
Loa Loa (eye worm) hypothetical protein 0.0101 0.0528 0.0887
Giardia lamblia Histone acetyltransferase GCN5 0.0042 0.0183 0.0904
Loa Loa (eye worm) hypothetical protein 0.027 0.1511 0.2563
Treponema pallidum exodeoxyribonuclease (exoA) 0.0022 0.0071 0.4524
Trichomonas vaginalis chromobox protein, putative 0.0013 0.0015 0.0032
Brugia malayi CHD4 protein 0.0016 0.0037 0.0051
Schistosoma mansoni cellular tumor antigen P53 0.0053 0.0248 0.0472
Echinococcus multilocularis chromodomain helicase DNA binding protein 1 0.0013 0.0015 0.0009
Trypanosoma brucei apurinic/apyrimidinic endonuclease, putative 0.0022 0.0071 0.1036
Brugia malayi Pin1-type peptidyl-prolyl cis-trans isomerase, BmPin1 0.004 0.0176 0.0288
Entamoeba histolytica phosphatidylinositol3-kinaseTor2, putative 0.0018 0.0046 0.0199
Loa Loa (eye worm) isocitrate dehydrogenase 0.0031 0.0122 0.0196
Trypanosoma brucei peptidyl-prolyl cis-trans isomerase/rotamase, putative 0.0039 0.017 0.2647
Trichomonas vaginalis prolyl-tRNA synthetase, putative 0.0101 0.0528 0.1938
Mycobacterium ulcerans beta-lactamase 0.004 0.0176 0.456
Loa Loa (eye worm) hypothetical protein 0.0053 0.0248 0.041
Entamoeba histolytica Ran family GTPase 0.0026 0.009 0.0428
Echinococcus granulosus survival motor neuron protein 1 0.027 0.1511 0.2873
Mycobacterium tuberculosis Lysyl-tRNA synthetase 1 LysS (lysine--tRNA ligase 1) (LysRS 1) (lysine translase) 0.0064 0.0312 0.2038
Leishmania major modification methylase-like protein 0.002 0.0055 0.0784
Trypanosoma cruzi cytochrome p450-like protein, putative 0.0014 0.0023 0.0256
Brugia malayi SET domain containing protein 0.0016 0.0036 0.005
Echinococcus granulosus FKBP12 rapamycin complex associated protein 0.0018 0.0046 0.0075
Trichomonas vaginalis sugar transporter, putative 0.0047 0.0216 0.0778
Schistosoma mansoni lysyl-tRNA synthetase 0.0075 0.0377 0.0719
Mycobacterium ulcerans acyl-CoA synthetase 0.0027 0.0096 0.2396
Loa Loa (eye worm) hypothetical protein 0.0027 0.0096 0.0151
Brugia malayi PHD-finger family protein 0.0013 0.0018 0.0018
Loa Loa (eye worm) hypothetical protein 0.004 0.0176 0.0288
Entamoeba histolytica acyl-CoA synthetase, putative 0.0027 0.0096 0.0455
Trichomonas vaginalis rotamase, putative 0.004 0.0176 0.0629
Loa Loa (eye worm) hypothetical protein 0.005 0.0231 0.0382
Plasmodium vivax hypothetical protein, conserved 0.0013 0.0019 0.0015
Trichomonas vaginalis set domain proteins, putative 0.0473 0.2694 1
Trichomonas vaginalis conserved hypothetical protein 0.0014 0.0025 0.0069
Plasmodium vivax calcium-dependent protein kinase 1, putative 0.0103 0.054 0.0648
Trichomonas vaginalis sugar transporter, putative 0.0047 0.0216 0.0778
Toxoplasma gondii facilitative glucose transporter GT1 0.0336 0.1896 0.3462
Schistosoma mansoni Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) 0.0144 0.0781 0.149
Echinococcus granulosus histidyl tRNA synthetase 0.0011 0.0007 0.0001
Trichomonas vaginalis chromodomain helicase DNA binding protein, putative 0.0027 0.01 0.0346
Plasmodium vivax isocitrate dehydrogenase [NADP], mitochondrial, putative 0.0031 0.0122 0.014
Leishmania major prolyl-tRNA synthetase, putative,bifunctional aminoacyl-tRNA synthetase, putative 0.0117 0.0625 1
Mycobacterium leprae PROBABLE FATTY-ACID-CoA LIGASE FADD7 (FATTY-ACID-CoA SYNTHETASE) (FATTY-ACID-CoA SYNTHASE) 0.0027 0.0096 0.1446
Loa Loa (eye worm) glycyl-tRNA synthetase 0.0019 0.0051 0.0075
Trypanosoma brucei sugar transporter, putative 0.0047 0.0216 0.3384
Trypanosoma cruzi phosphatidylinositol 3-related kinase, putative 0.0018 0.0046 0.0628
Toxoplasma gondii HEAT repeat-containing protein 0.0035 0.0144 0.0251
Plasmodium falciparum major facilitator superfamily domain-containing protein, putative 0.0047 0.0216 0.0254
Schistosoma mansoni chromobox protein 0.0078 0.0395 0.0754
Trichomonas vaginalis PIKK family atypical protein kinase 0.0018 0.0046 0.0145
Trichomonas vaginalis PIKK family atypical protein kinase 0.0018 0.0046 0.0145
Loa Loa (eye worm) jmjC domain-containing protein 0.0039 0.0167 0.0273
Trichomonas vaginalis PIKK family atypical protein kinase 0.0018 0.0046 0.0145
Schistosoma mansoni glucose transport protein 0.0336 0.1896 0.3614
Onchocerca volvulus 0.004 0.0176 0.0599
Leishmania major peptidyl-prolyl cis-trans isomerase/rotamase, putative,PPIase, putative 0.0039 0.017 0.2647
Mycobacterium ulcerans fusion protein of transposase for IS2606 and sialic acid-transport integral membrane protein NanT 0.0047 0.0216 0.5643
Echinococcus multilocularis Jumonji, AT rich interactive domain 1B 0.0013 0.0017 0.0011
Trypanosoma brucei calcium/calmodulin-dependent protein kinase, putative 0.0103 0.054 0.8623
Plasmodium vivax glycine--tRNA ligase, putative 0.0019 0.0051 0.0054
Trichomonas vaginalis chromobox protein, putative 0.0047 0.0215 0.0775
Echinococcus granulosus histone lysine N methyltransferase MLL3 0.0018 0.0046 0.0076
Schistosoma mansoni protein kinase 0.0103 0.054 0.1029
Trichomonas vaginalis PIKK family atypical protein kinase 0.0018 0.0046 0.0145
Mycobacterium ulcerans cytochrome P450 126A3 Cyp126A3 0.0014 0.0023 0.0427
Echinococcus granulosus solute carrier family 22 0.0047 0.0216 0.04
Trichomonas vaginalis conserved hypothetical protein 0.0013 0.0015 0.0032
Leishmania major hypothetical protein, conserved 0.004 0.0176 0.2735
Giardia lamblia Hexose transporter 0.0047 0.0216 0.1071
Echinococcus multilocularis calcium:calmodulin dependent protein kinase type 0.0103 0.054 0.0534
Leishmania major hypothetical protein, conserved 0.003 0.0118 0.1804
Trypanosoma cruzi hypothetical protein, conserved 0.0017 0.0038 0.0508
Echinococcus granulosus tumor protein p63 0.036 0.2035 0.3872
Mycobacterium ulcerans cytochrome P450 124A1, Cyp124A1 0.0014 0.0023 0.0427
Onchocerca volvulus 0.0097 0.0507 0.1836
Echinococcus multilocularis peregrin 0.0033 0.0132 0.0126
Brugia malayi Voltage-gated calcium channel, T-type, alpha subunit. C. elegans cca-1 ortholog 0.0176 0.0963 0.163
Echinococcus multilocularis solute carrier family 2 facilitated glucose 0.0336 0.1896 0.1891
Trichomonas vaginalis ap endonuclease, putative 0.0022 0.0071 0.0238
Trichomonas vaginalis PIKK family atypical protein kinase 0.0018 0.0046 0.0145
Leishmania major phosphatidylinositol 3-related kinase, putative 0.0018 0.0046 0.0628
Trichomonas vaginalis conserved hypothetical protein 0.0014 0.0025 0.0069
Onchocerca volvulus 0.0055 0.0261 0.0918
Loa Loa (eye worm) CAMK/CAMK2 protein kinase 0.0103 0.054 0.0908
Trichomonas vaginalis conserved hypothetical protein 0.0013 0.0015 0.0032
Loa Loa (eye worm) nucleolar RNA-associated protein alpha 0.0372 0.2106 0.3576
Mycobacterium tuberculosis Probable fatty-acid-CoA ligase FadD3 (fatty-acid-CoA synthetase) (fatty-acid-CoA synthase) 0.0019 0.005 0.0195
Schistosoma mansoni chromobox protein-related (chromobox 1) (heterochromatin 1) 0.0013 0.0015 0.0029
Loa Loa (eye worm) major facilitator superfamily transporter 0.0047 0.0216 0.0356
Chlamydia trachomatis lysine--tRNA ligase 0.0075 0.0377 1
Trypanosoma brucei phosphatidylinositol 3-related kinase, putative 0.0018 0.0046 0.0629
Loa Loa (eye worm) helicase 0.0013 0.0015 0.0015
Trichomonas vaginalis D-aminoacylase, putative 0.004 0.0176 0.0629
Mycobacterium ulcerans acyl-CoA synthetase 0.0027 0.0096 0.2396
Echinococcus multilocularis calcium:calmodulin dependent protein kinase type 0.0103 0.054 0.0534
Trichomonas vaginalis chromodomain helicase DNA binding protein, putative 0.0027 0.01 0.0346
Plasmodium falciparum ataxin-2 like protein, putative 0.003 0.0118 0.0135
Loa Loa (eye worm) threonyl-tRNA synthetase 0.0019 0.0051 0.0075
Trypanosoma brucei glucose transporter, putative 0.0104 0.0547 0.8748
Toxoplasma gondii YbaK/proline-tRNA ligase associated domain-containing protein 0.0017 0.0038 0.0058
Brugia malayi chromobox protein homolog 3 0.0044 0.0196 0.0322
Mycobacterium tuberculosis Probable threonyl-tRNA synthetase ThrS (threonine-tRNA synthetase)(ThrRS) (threonine-tRNA ligase) 0.0019 0.0051 0.02
Brugia malayi Bifunctional aminoacyl-tRNA synthetase 0.0101 0.0528 0.0887
Schistosoma mansoni hypothetical protein 0.0055 0.0261 0.0498
Mycobacterium ulcerans hypothetical protein 0.0027 0.0096 0.2396
Trypanosoma brucei isocitrate dehydrogenase, putative 0.0031 0.0122 0.186
Toxoplasma gondii ABC1 family protein 0.004 0.0176 0.031
Echinococcus multilocularis chromodomain helicase DNA binding protein 4 0.0016 0.0037 0.003
Trypanosoma brucei GTP-binding nuclear protein rtb2, putative 0.0026 0.009 0.1351
Trichomonas vaginalis conserved hypothetical protein 0.0014 0.0025 0.0069
Plasmodium falciparum threonine--tRNA ligase 0.0019 0.0051 0.0054
Schistosoma mansoni importin beta-1 0.0035 0.0144 0.0274
Schistosoma mansoni sugar transporter 0.0047 0.0216 0.0412
Mycobacterium ulcerans cytochrome P450 125A7 Cyp125A7 0.0014 0.0023 0.0427
Loa Loa (eye worm) hypothetical protein 0.002 0.0057 0.0085
Brugia malayi Hypothetical 52.5 kDa protein ZK945.1 in chromosome II, putative 0.004 0.0176 0.0288
Mycobacterium ulcerans fatty-acid-CoA ligase 0.0027 0.0096 0.2396
Schistosoma mansoni ran 0.0026 0.009 0.0172
Loa Loa (eye worm) exodeoxyribonuclease III family protein 0.0022 0.0071 0.0109
Toxoplasma gondii sugar transporter ST2 0.0047 0.0216 0.0383
Trichomonas vaginalis PIKK family atypical protein kinase 0.0018 0.0046 0.0145
Brugia malayi follicle stimulating hormone receptor 0.1019 0.5876 1
Trichomonas vaginalis PIKK family atypical protein kinase 0.0018 0.0046 0.0145
Trichomonas vaginalis conserved hypothetical protein 0.0013 0.0015 0.0032
Plasmodium falciparum AP endonuclease (DNA-[apurinic or apyrimidinic site] lyase), putative 0.0022 0.0071 0.0078
Wolbachia endosymbiont of Brugia malayi threonyl-tRNA synthetase 0.0019 0.0051 0.2114
Brugia malayi Doublecortin family protein 0.0042 0.0188 0.0309
Brugia malayi isocitrate dehydrogenase 0.0031 0.0122 0.0196
Echinococcus granulosus disco interacting protein 2 0.0039 0.017 0.0313
Echinococcus granulosus solute carrier family 2 facilitated glucose 0.0336 0.1896 0.3607
Schistosoma mansoni tar DNA-binding protein 0.0065 0.0321 0.0611
Echinococcus granulosus lipoxygenase domain containing protein 0.0042 0.0188 0.0347
Loa Loa (eye worm) hypothetical protein 0.0021 0.0065 0.0099
Toxoplasma gondii chromodomain helicase DNA binding protein CHD1/SWI2/SNF2 0.0013 0.0015 0.0016
Echinococcus multilocularis GPCR, family 2 0.0086 0.0444 0.0438
Entamoeba histolytica DNA repair and recombination protein RAD52, putative 0.0347 0.1959 1
Trichomonas vaginalis chromodomain helicase DNA binding protein, putative 0.0013 0.0015 0.0032
Loa Loa (eye worm) calcium/calmodulin-dependent protein kinase ID 0.0103 0.054 0.0908
Mycobacterium tuberculosis Probable fatty-acid-CoA ligase FadD7 (fatty-acid-CoA synthetase) (fatty-acid-CoA synthase) 0.0019 0.005 0.0195
Trichomonas vaginalis conserved hypothetical protein 0.0017 0.0038 0.0117
Giardia lamblia DNA repair protein RAD52 0.0347 0.1959 1
Trypanosoma cruzi Lanosterol 14-alpha demethylase 0.0014 0.0023 0.0256
Schistosoma mansoni hypothetical protein 0.0029 0.011 0.021
Schistosoma mansoni glucose transporter 0.0047 0.0216 0.0412
Trichomonas vaginalis conserved hypothetical protein 0.0013 0.0015 0.0032
Trypanosoma brucei phosphatidylinositol 4-kinase, putative 0.0018 0.0046 0.0629
Schistosoma mansoni hypothetical protein 0.0086 0.0444 0.0847
Toxoplasma gondii histone lysine methyltransferase SET1 0.0127 0.0681 0.1236
Echinococcus granulosus guanine nucleotide binding protein Gs subunit 0.0144 0.0781 0.1479
Schistosoma mansoni polycystin 1-related 0.0042 0.0188 0.0359
Schistosoma mansoni tar DNA-binding protein 0.0065 0.0321 0.0611
Brugia malayi Cytochrome P450 family protein 0.0014 0.0023 0.0027
Trypanosoma brucei PAB1-binding protein , putative 0.003 0.0118 0.1804
Schistosoma mansoni ap endonuclease 0.0022 0.0071 0.0135
Trichomonas vaginalis sugar transporter, putative 0.0047 0.0216 0.0778
Trichomonas vaginalis sugar transporter, putative 0.0104 0.0547 0.2012
Brugia malayi MH2 domain containing protein 0.0139 0.0749 0.1265
Trypanosoma cruzi importin beta-1 subunit, putative 0.0028 0.0105 0.1596
Trichomonas vaginalis chromodomain-helicase-DNA-binding protein, putative 0.0027 0.01 0.0346
Brugia malayi beta-lactamase 0.004 0.0176 0.0288
Echinococcus multilocularis serine protein kinase ATM 0.0025 0.0085 0.0078
Schistosoma mansoni aspartyl-tRNA synthetase 0.0011 0.0007 0.0013
Toxoplasma gondii histone lysine acetyltransferase GCN5-B 0.0045 0.0205 0.0364
Echinococcus granulosus importin subunit beta 1 0.0035 0.0144 0.0262
Schistosoma mansoni hypothetical protein 0.0086 0.0444 0.0847
Trichomonas vaginalis interferon-induced, double-stranded RNA-activated protein kinase, putative 0.0011 0.0007 0.0001
Echinococcus granulosus lipoxygenase domain containing protein 0.0042 0.0188 0.0347
Trichomonas vaginalis sugar transporter, putative 0.0104 0.0547 0.2012
Plasmodium falciparum histone acetyltransferase GCN5 0.0042 0.0183 0.0214
Trichomonas vaginalis rotamase, putative 0.0039 0.017 0.0609
Trichomonas vaginalis PIKK family atypical protein kinase 0.0018 0.0046 0.0145
Echinococcus granulosus DNA apurinic or apyrimidinic site lyase 0.0022 0.0071 0.0123
Loa Loa (eye worm) transcription factor SMAD2 0.0139 0.0749 0.1265
Trypanosoma cruzi hexose transporter 0.0104 0.0547 0.8747
Trichomonas vaginalis sugar transporter, putative 0.0047 0.0216 0.0778
Onchocerca volvulus 0.0047 0.0216 0.0749
Loa Loa (eye worm) hypothetical protein 0.0013 0.0015 0.0015
Brugia malayi AMP-binding enzyme family protein 0.0027 0.0096 0.0151
Brugia malayi Associated with TFs and helicases family protein 0.0013 0.0015 0.0015
Mycobacterium ulcerans cytochrome P450 136A2 Cyp136A2 0.0014 0.0023 0.0427
Onchocerca volvulus 0.004 0.0176 0.0599
Loa Loa (eye worm) hypothetical protein 0.0047 0.0216 0.0356
Trichomonas vaginalis sugar transporter, putative 0.0047 0.0216 0.0778
Echinococcus granulosus serine protein kinase ATM 0.0025 0.0085 0.015
Schistosoma mansoni hypothetical protein 0.0086 0.0444 0.0847
Trypanosoma brucei THT1 - hexose transporter, putative 0.0104 0.0547 0.8748
Echinococcus multilocularis Sugar transporter ERD6 protein 0.0047 0.0216 0.021
Echinococcus granulosus arachidonate 5 lipoxygenase 0.0254 0.1419 0.2697
Brugia malayi M-phase phosphoprotein, mpp8 0.0013 0.0015 0.0015
Brugia malayi threonyl-tRNA synthetase, cytoplasmic 0.0019 0.0051 0.0075
Echinococcus granulosus solute carrier family 22 0.0047 0.0216 0.04
Echinococcus multilocularis importin subunit beta 1 0.0035 0.0144 0.0137
Trypanosoma cruzi phosphatidylinositol 3-related kinase, putative 0.0018 0.0046 0.0628
Trichomonas vaginalis sugar transporter, putative 0.0047 0.0216 0.0778
Brugia malayi Phosphatidylinositol 3- and 4-kinase family protein 0.0025 0.0085 0.0133
Brugia malayi Calcitonin receptor-like protein seb-1 0.0273 0.1532 0.2598
Trichomonas vaginalis PIKK family atypical protein kinase 0.0018 0.0046 0.0145
Entamoeba histolytica hypothetical protein 0.0013 0.0015 0.0044
Trypanosoma cruzi hexose transporter, putative 0.0104 0.0547 0.8747
Leishmania major threonyl-tRNA synthetase, putative 0.0019 0.0051 0.0715
Trichomonas vaginalis threonyl-tRNA synthetase, putative 0.0019 0.0051 0.0165
Mycobacterium leprae conserved hypothetical protein 0.0017 0.0038 0.0309
Brugia malayi beta-lactamase family protein 0.004 0.0176 0.0288
Trypanosoma cruzi isocitrate dehydrogenase, putative 0.0031 0.0122 0.1859
Toxoplasma gondii 'chromo' (CHRromatin Organization MOdifier) domain-containing protein 0.0013 0.0015 0.0016
Mycobacterium ulcerans cytochrome P450 51B1 Cyp51B1 0.0014 0.0023 0.0427
Toxoplasma gondii LsmAD domain-containing protein 0.003 0.0118 0.0204
Trichomonas vaginalis sugar transporter, putative 0.0047 0.0216 0.0778
Echinococcus granulosus GTP binding nuclear protein Ran 0.0026 0.009 0.016
Loa Loa (eye worm) hypothetical protein 0.004 0.0176 0.0288
Chlamydia trachomatis threonine--tRNA ligase 0.0019 0.0051 0.1193
Entamoeba histolytica exodeoxyribonuclease III, putative 0.0022 0.0071 0.0328
Brugia malayi Heterochromatin protein 1 0.0078 0.0395 0.0662
Trypanosoma cruzi hexose transporter, putative 0.0057 0.0272 0.4299
Loa Loa (eye worm) hypothetical protein 0.0047 0.0216 0.0356
Trypanosoma cruzi glycyl-tRNA synthetase, putative 0.0011 0.0007 0.0005
Loa Loa (eye worm) histidyl-tRNA synthetase 0.0011 0.0007 0.0001
Leishmania major apurinic/apyrimidinic endonuclease-redox protein 0.0022 0.0071 0.1035
Echinococcus multilocularis geminin 0.0749 0.4301 0.4298
Plasmodium vivax DNA (cytosine-5)-methyltransferase, putative 0.002 0.0055 0.0059
Brugia malayi Major Facilitator Superfamily protein 0.0047 0.0216 0.0356
Mycobacterium tuberculosis Possible penicillin-binding protein 0.0258 0.1441 1
Echinococcus granulosus chromobox protein 2 0.0013 0.0015 0.0017
Loa Loa (eye worm) GTP-binding nuclear protein RAN/TC4 0.0026 0.009 0.0142
Trichomonas vaginalis glycyl-tRNA synthetase, putative 0.0011 0.0007 0.0001
Trypanosoma brucei asparaginyl-tRNA synthetase, putative 0.0011 0.0007 0.0001
Mycobacterium tuberculosis Conserved protein 0.004 0.0176 0.108
Entamoeba histolytica hypothetical protein 0.0013 0.0015 0.0044
Chlamydia trachomatis histidine--tRNA ligase 0.0011 0.0007 0.0008
Schistosoma mansoni glucose transport protein 0.0336 0.1896 0.3614
Echinococcus granulosus chromobox protein 1 0.0078 0.0395 0.0742
Loa Loa (eye worm) phosphatidylinositol 3 0.0018 0.0046 0.0066
Entamoeba histolytica hypothetical protein 0.0075 0.0377 0.1899
Echinococcus granulosus jumonji domain containing protein 0.004 0.0176 0.0325
Plasmodium falciparum conserved Plasmodium protein, unknown function 0.0013 0.0015 0.001
Schistosoma mansoni ap endonuclease 0.0022 0.0071 0.0135
Loa Loa (eye worm) RNA binding protein 0.0065 0.0321 0.0535
Mycobacterium ulcerans prolyl-tRNA synthetase 0.0036 0.0148 0.3815
Trichomonas vaginalis conserved hypothetical protein 0.0014 0.0025 0.0069
Giardia lamblia Sugar-proton symporter 0.0047 0.0216 0.1071
Loa Loa (eye worm) hypothetical protein 0.002 0.0057 0.0085
Trypanosoma cruzi prolyl-tRNA synthetase, putative 0.0117 0.0625 1
Echinococcus multilocularis guanine nucleotide binding protein G(s) subunit 0.0144 0.0781 0.0776
Mycobacterium tuberculosis Probable chain -fatty-acid-CoA ligase FadD13 (fatty-acyl-CoA synthetase) 0.0027 0.0096 0.0515
Trichomonas vaginalis PIKK family atypical protein kinase 0.0018 0.0046 0.0145
Leishmania major phosphatidylinositol 3-kinase, putative 0.0018 0.0046 0.0628
Schistosoma mansoni lipoxygenase 0.0254 0.1419 0.2706
Loa Loa (eye worm) hypothetical protein 0.0047 0.0216 0.0356
Schistosoma mansoni tar DNA-binding protein 0.0065 0.0321 0.0611
Plasmodium vivax sugar transporter, putative 0.0047 0.0216 0.0254
Toxoplasma gondii isocitrate dehydrogenase 0.0031 0.0122 0.0211
Trypanosoma brucei target of rapamycin kinase 3, putative 0.0018 0.0046 0.0629
Loa Loa (eye worm) hypothetical protein 0.0101 0.0528 0.0887
Brugia malayi Cytochrome P450 family protein 0.0014 0.0023 0.0027
Onchocerca volvulus 0.0047 0.0216 0.0749
Onchocerca volvulus 0.0047 0.0216 0.0749
Loa Loa (eye worm) hypothetical protein 0.004 0.0176 0.0288
Loa Loa (eye worm) hypothetical protein 0.0047 0.0216 0.0356
Onchocerca volvulus 0.0013 0.0015 0.000000054091
Brugia malayi jmjC domain containing protein 0.0039 0.0167 0.0273
Toxoplasma gondii lysine-tRNA ligase 0.0075 0.0377 0.0679
Plasmodium falciparum protein kinase 7 0.0949 0.5465 0.663
Toxoplasma gondii DNA methyltransferase 2, putative 0.002 0.0055 0.0089
Loa Loa (eye worm) 63kd antigen 0.0011 0.0007 0.0000066056
Schistosoma mansoni threonyl-tRNA synthetase 0.0011 0.0007 0.0013
Entamoeba histolytica acyl-CoA synthetase, putative 0.0027 0.0096 0.0455
Trichomonas vaginalis CAMK family protein kinase 0.0103 0.054 0.1983
Echinococcus granulosus cadherin EGF LAG seven pass G type receptor 0.0086 0.0444 0.0836
Trichomonas vaginalis conserved hypothetical protein 0.0014 0.0025 0.0069
Toxoplasma gondii threonyl-tRNA synthetase family protein 0.0019 0.0051 0.0081
Treponema pallidum glycyl-tRNA synthetase 0.0011 0.0007 0.002
Loa Loa (eye worm) hypothetical protein 0.0047 0.0216 0.0356
Trypanosoma cruzi sugar transporter, putative 0.0047 0.0216 0.3384
Trichomonas vaginalis hypothetical protein 0.0013 0.0015 0.0032
Trichomonas vaginalis sugar transporter, putative 0.0047 0.0216 0.0778
Mycobacterium ulcerans cytochrome P450 143A3 Cyp143A3 0.0014 0.0023 0.0427

Activities

Activity type Activity value Assay description Source Reference
Potency (functional) 2.5119 uM PubChem BioAssay. qHTS for Activators of Integrin-Mediated Alleviation for Muscular Dystrophy. (Class of assay: confirmatory) ChEMBL. No reference
Potency (functional) 10 uM PubChem BioAssay. qHTS for Inhibitors of ATXN expression. (Class of assay: confirmatory) ChEMBL. No reference
Potency (functional) 12.5893 uM PubChem BioAssay. qHTS Assay to Find Inhibitors of Pin1. (Class of assay: confirmatory) ChEMBL. No reference
Potency (binding) 14.1254 uM PubChem BioAssay. qHTS Assay for Inhibitors of MBNL1-poly(CUG) RNA binding. (Class of assay: confirmatory) ChEMBL. No reference
Potency (functional) 15.8489 uM PubChem BioAssay. qHTS of GLP-1 Receptor Inverse Agonists (Inhibition Mode). (Class of assay: confirmatory) ChEMBL. No reference
Potency (functional) 16.3601 uM PubChem BioAssay. A quantitative high throughput screen for small molecules that induce DNA re-replication in MCF 10a normal breast cells. (Class of assay: confirmatory) ChEMBL. No reference
Potency (functional) 16.3601 uM PUBCHEM_BIOASSAY: qHTS Assay for Inhibitors of RanGTP induced Rango (Ran-regulated importin-beta cargo) - Importin beta complex dissociation. (Class of assay: confirmatory) [Related pubchem assays (depositor defined):AID540262] ChEMBL. No reference
Potency (functional) 29.0929 uM PubChem BioAssay. A quantitative high throughput screen for small molecules that induce DNA re-replication in SW480 colon adenocarcinoma cells. (Class of assay: confirmatory) ChEMBL. No reference
Potency (functional) 35.4813 uM PUBCHEM_BIOASSAY: qHTS for Inhibitors of binding or entry into cells for Lassa Virus. (Class of assay: confirmatory) [Related pubchem assays (depositor defined):AID463114, AID540249] ChEMBL. No reference
Potency (functional) 39.8107 uM PUBCHEM_BIOASSAY: qHTS for Inhibitors of Polymerase Iota. (Class of assay: confirmatory) [Related pubchem assays (depositor defined):AID588623] ChEMBL. No reference

Phenotypes

Whole-cell/tissue/organism interactions

We have no records of whole-cell/tissue assays done with this compound What does this mean?

Many chemical entities in TDR Targets come from high-throughput screenings with whole cells or tissue samples, and not all assayed compounds have been tested against a single a single target protein, probably because they get ruled out during screening process. Even if these compounds may have not been of interest in the original screening, they may come as interesting leads for other screening assays. Furthermore, we may be able to propose drug-target associations using chemical similarities and network patterns.

Annotated phenotypes:

We have no manually annotated phenotypes for this drug. What does this mean? / Care to help?
In TDR Targets, information about phenotypes that are caused by drugs, or by genetic manipulation of cells (e.g. gene knockouts or knockdowns) is manually curated from the literature. These descriptions help to describe the potential of the target for drug development. If no information is available for this gene or if the information is incomplete, this may mean that i) the papers containing this information either appeared after the curation effort for this organism was carried out or they were inadvertently missed by curators; or that ii) the curation effort for this organism has not yet started.
 
In any case, if you have information about papers containing relevant validation data for this target, please log in using your TDR Targets username and password and send them to us using the corresponding form in this page (only visible to registered users) or contact us.

External resources for this compound

Bibliographic References

No literature references available for this target.

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