Detailed information for compound 1335681

Basic information

Technical information
  • TDR Targets ID: 1335681
  • Name: 2-chloro-N-[[5-[2-[(3,5-dimethylphenyl)amino] -2-oxoethyl]sulfanyl-1,3,4-oxadiazol-2-yl]met hyl]-6-fluorobenzamide
  • MW: 448.898 | Formula: C20H18ClFN4O3S
  • H donors: 2 H acceptors: 4 LogP: 3.76 Rotable bonds: 9
    Rule of 5 violations (Lipinski): 1
  • SMILES: O=C(Nc1cc(C)cc(c1)C)CSc1nnc(o1)CNC(=O)c1c(F)cccc1Cl
  • InChi: 1S/C20H18ClFN4O3S/c1-11-6-12(2)8-13(7-11)24-16(27)10-30-20-26-25-17(29-20)9-23-19(28)18-14(21)4-3-5-15(18)22/h3-8H,9-10H2,1-2H3,(H,23,28)(H,24,27)
  • InChiKey: MPEXHFJQGDIULH-UHFFFAOYSA-N  


Substructure search Similarity search

Network

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Synonyms

  • 2-chloro-N-[[5-[2-[(3,5-dimethylphenyl)amino]-2-oxo-ethyl]sulfanyl-1,3,4-oxadiazol-2-yl]methyl]-6-fluoro-benzamide
  • 2-chloro-N-[[5-[[2-[(3,5-dimethylphenyl)amino]-2-oxoethyl]thio]-1,3,4-oxadiazol-2-yl]methyl]-6-fluorobenzamide
  • 2-chloro-N-[[5-[[2-[(3,5-dimethylphenyl)amino]-2-keto-ethyl]thio]-1,3,4-oxadiazol-2-yl]methyl]-6-fluoro-benzamide
  • C328-0219
  • NCGC00107712-01

Targets

Known targets for this compound

Species Target name Source Bibliographic reference
Homo sapiens bromodomain adjacent to zinc finger domain, 2B Starlite/ChEMBL No references
Homo sapiens survival of motor neuron 2, centromeric Starlite/ChEMBL No references
Homo sapiens nuclear factor, erythroid 2-like 2 Starlite/ChEMBL No references

Predicted pathogen targets for this compound

By orthology
Species Potential target Known druggable target/s Ortholog Group
Echinococcus granulosus survival motor neuron protein 1 Get druggable targets OG5_132873 All targets in OG5_132873
Echinococcus granulosus bromodomain adjacent to zinc finger domain Get druggable targets OG5_131570 All targets in OG5_131570
Schistosoma japonicum hypothetical protein Get druggable targets OG5_131570 All targets in OG5_131570
Loa Loa (eye worm) hypothetical protein Get druggable targets OG5_131570 All targets in OG5_131570
Loa Loa (eye worm) hypothetical protein Get druggable targets OG5_131570 All targets in OG5_131570
Echinococcus multilocularis survival motor neuron protein 1 Get druggable targets OG5_132873 All targets in OG5_132873
Schistosoma japonicum ko:K01549 ATP synthase [EC3.6.3.14], putative Get druggable targets OG5_131570 All targets in OG5_131570
Echinococcus multilocularis bromodomain adjacent to zinc finger domain Get druggable targets OG5_131570 All targets in OG5_131570
Loa Loa (eye worm) hypothetical protein Get druggable targets OG5_131570 All targets in OG5_131570
Loa Loa (eye worm) hypothetical protein Get druggable targets OG5_131570 All targets in OG5_131570
Schistosoma japonicum Cleft lip and palate transmembrane protein 1-like protein, putative Get druggable targets OG5_131570 All targets in OG5_131570
Schistosoma mansoni bromodomain containing protein Get druggable targets OG5_131570 All targets in OG5_131570
Schistosoma japonicum Conserved hypothetical protein Get druggable targets OG5_131570 All targets in OG5_131570
Schistosoma japonicum expressed protein Get druggable targets OG5_131570 All targets in OG5_131570
Brugia malayi hypothetical protein Get druggable targets OG5_132873 All targets in OG5_132873
Loa Loa (eye worm) hypothetical protein Get druggable targets OG5_132873 All targets in OG5_132873
Brugia malayi Bromodomain containing protein Get druggable targets OG5_131570 All targets in OG5_131570
By sequence similarity to non orthologous known druggable targets
No druggable targets predicted by sequence similarity
Obtained from network model

Ranking Plot

Putative Targets List

Species Potential target Raw Global Species
Echinococcus granulosus expressed protein 0.0089 0.0091 0.0114
Echinococcus granulosus mitogen activated protein kinase 0.0141 0.0359 0.0462
Brugia malayi hypothetical protein 0.0413 0.1772 0.1755
Brugia malayi serine/threonine protein kinase 6 0.0208 0.0709 0.0691
Echinococcus multilocularis glycine receptor subunit alpha 1 0.017 0.0509 0.0798
Echinococcus granulosus protein kinase shaggy 0.0181 0.0568 0.0733
Loa Loa (eye worm) hypothetical protein 0.0141 0.0361 0.0342
Echinococcus granulosus roundabout 2 0.0176 0.0539 0.0696
Giardia lamblia Kinase, AGC AKT 0.0122 0.026 0.1186
Trichomonas vaginalis CAMK family protein kinase 0.0188 0.0605 0.3709
Loa Loa (eye worm) CMGC/CDK/CDC2 protein kinase 0.021 0.0717 0.0699
Echinococcus granulosus serine:threonine protein kinase mig 15 0.0223 0.0784 0.1015
Echinococcus multilocularis Immunoglobulin 0.0123 0.0269 0.0419
Echinococcus multilocularis cyclin B3 1 0.0146 0.0385 0.0603
Brugia malayi Cation transporter family protein 0.017 0.0509 0.049
Entamoeba histolytica protein kinase, putative 0.0176 0.0542 0.3563
Schistosoma mansoni serine/threonine protein kinase 0.021 0.0717 0.1104
Entamoeba histolytica PH domain containing protein kinase, putative 0.0169 0.0504 0.3313
Onchocerca volvulus 0.017 0.0509 0.1972
Loa Loa (eye worm) CK1/CK1/CK1-D protein kinase 0.0114 0.0218 0.0199
Echinococcus multilocularis titin 0.0075 0.002 0.0026
Loa Loa (eye worm) CMGC/MAPK/ERK1 protein kinase 0.0141 0.0359 0.034
Echinococcus granulosus Cys loop ligand gated ion channel subunit 0.017 0.0509 0.0656
Echinococcus granulosus Ribosomal protein S6 kinase beta 2 0.0176 0.0542 0.07
Echinococcus granulosus tyrosine protein kinase Lyn 0.0319 0.1283 0.1662
Schistosoma mansoni cyclin-dependent kinase 5 activator 0.0259 0.0973 0.1509
Trichomonas vaginalis cyclin D, putative 0.0146 0.0385 0.2257
Brugia malayi kinase, mitochondrial precursor 0.0121 0.0254 0.0235
Brugia malayi Protein kinase domain containing protein 0.0209 0.0715 0.0697
Echinococcus multilocularis N chimaerin 0.0125 0.0276 0.0431
Loa Loa (eye worm) hypothetical protein 0.0078 0.0035 0.0015
Echinococcus multilocularis insulin receptor 0.0892 0.4252 0.6709
Loa Loa (eye worm) excitatory GABA receptor EXP-1A 0.017 0.0509 0.049
Loa Loa (eye worm) hypothetical protein 0.0165 0.0485 0.0467
Loa Loa (eye worm) hypothetical protein 0.017 0.0509 0.049
Echinococcus multilocularis serine:threonine protein kinase Chk2 0.0077 0.003 0.0042
Brugia malayi Protein kinase c protein 2 0.0168 0.0499 0.048
Echinococcus multilocularis tyrosine protein kinase 0.0296 0.1161 0.1829
Echinococcus multilocularis 0.0156 0.044 0.0689
Trypanosoma brucei STE/STE11 serine/threonine-protein kinase, putative 0.0106 0.0179 0.0521
Echinococcus granulosus ephrin type A receptor 4 A 0.0127 0.0286 0.0368
Echinococcus granulosus macrophage colony stimulating factor 1 receptor 0.1558 0.7703 1
Schistosoma mansoni growth factor receptor-bound protein 0.0128 0.0295 0.0437
Trichomonas vaginalis serine/threonine-protein kinase sgk, putative 0.0135 0.0331 0.1896
Echinococcus multilocularis mitogen activated protein kinase 0.0141 0.0359 0.0562
Brugia malayi Dual-specificity tyrosine-phosphorylation regulated kinase 2 0.0143 0.0369 0.035
Brugia malayi Protein kinase domain containing protein 0.0188 0.0605 0.0587
Brugia malayi Variant SH3 domain containing protein 0.0125 0.0276 0.0257
Brugia malayi protein kinase C II. 0.0225 0.0795 0.0777
Loa Loa (eye worm) CMGC/CDK/CDK9 protein kinase 0.0086 0.0077 0.0057
Echinococcus multilocularis serine:threonine protein kinase 0.008 0.0043 0.0063
Echinococcus granulosus dual specificity testis-specific protein kinase 0.0106 0.0179 0.0229
Brugia malayi Neurotransmitter-gated ion-channel ligand binding domain containing protein 0.0078 0.0035 0.0015
Plasmodium vivax calcium-dependent protein kinase, putative 0.0106 0.0179 0.2026
Loa Loa (eye worm) hypothetical protein 0.0134 0.0323 0.0304
Brugia malayi Immunoglobulin I-set domain containing protein 0.038 0.1597 0.158
Echinococcus multilocularis serine:threonine protein kinase 12 B 0.0208 0.0709 0.1114
Echinococcus multilocularis Pyruvate dehydrogenase (lipoamide) kinase 0.0121 0.0254 0.0396
Loa Loa (eye worm) hypothetical protein 0.0134 0.0323 0.0304
Echinococcus granulosus cyclins 0.0146 0.0385 0.0496
Loa Loa (eye worm) AGC/PKA protein kinase 0.0158 0.0449 0.043
Entamoeba histolytica protein kinase, putative 0.0181 0.0568 0.373
Schistosoma mansoni protein kinase 0.0106 0.0179 0.0253
Loa Loa (eye worm) CMGC/CK2 protein kinase 0.0105 0.0176 0.0156
Echinococcus multilocularis basic fibroblast growth factor receptor 1 A 0.0356 0.1472 0.232
Brugia malayi Protein kinase domain containing protein 0.0296 0.1161 0.1144
Leishmania major serine/threonine protein kinase, putative,protein kinase, putative 0.0095 0.0122 0.0185
Schistosoma mansoni serine/threonine protein kinase 0.0263 0.0993 0.1541
Schistosoma mansoni serine/threonine protein kinase 0.0158 0.0449 0.068
Giardia lamblia Hypothetical protein 0.0146 0.0385 0.2064
Echinococcus multilocularis serine:threonine protein kinase N2 0.0176 0.0542 0.0851
Onchocerca volvulus Suppressor of cytokine signaling at 36E homolog 0.0078 0.0036 0.0116
Brugia malayi Neurotransmitter-gated ion-channel ligand binding domain containing protein 0.017 0.0509 0.049
Brugia malayi protein kinase C3,putative 0.0167 0.0494 0.0475
Onchocerca volvulus 0.0144 0.0374 0.1444
Onchocerca volvulus Serine\/threonine kinase homolog 0.0167 0.0494 0.1916
Loa Loa (eye worm) TK/FAK protein kinase 0.0323 0.1304 0.1287
Schistosoma mansoni tyrosine kinase 0.0107 0.0184 0.026
Echinococcus granulosus glycine receptor subunit beta 0.017 0.0509 0.0656
Brugia malayi Neurotransmitter-gated ion-channel ligand binding domain containing protein 0.017 0.0509 0.049
Loa Loa (eye worm) TK/ABL protein kinase 0.0552 0.249 0.2475
Loa Loa (eye worm) CMGC/MAPK/P38 protein kinase 0.0416 0.1787 0.1771
Trypanosoma cruzi cdc2-related kinase 1 0.021 0.0717 0.399
Trichomonas vaginalis AGC family protein kinase 0.0176 0.0542 0.3294
Toxoplasma gondii NIMA-related protein kinase NIMA1 0.014 0.0355 0.2316
Echinococcus multilocularis protein kinase c iota type 0.0302 0.1195 0.1882
Plasmodium falciparum NIMA related kinase 1 0.014 0.0355 0.4314
Trichomonas vaginalis AGC family protein kinase 0.0326 0.1321 0.8433
Schistosoma mansoni cyclins 0.0146 0.0385 0.0579
Schistosoma mansoni serine/threonine protein kinase 0.0364 0.1517 0.2371
Brugia malayi SH2 domain containing protein 0.0078 0.0036 0.0016
Loa Loa (eye worm) TK/FER protein kinase 0.0144 0.0374 0.0355
Loa Loa (eye worm) hypothetical protein 0.0078 0.0035 0.0015
Schistosoma mansoni tyrosine-protein kinase zap-70 0.0078 0.0036 0.0026
Echinococcus multilocularis growth factor receptor bound protein 2 0.0128 0.0295 0.0462
Trichomonas vaginalis CAMK family protein kinase 0.0178 0.055 0.3346
Entamoeba histolytica protein kinase, putative 0.0143 0.0369 0.2425
Trypanosoma cruzi 5'-AMP-activated protein kinase catalytic subunit alpha, putative 0.0095 0.0122 0.0651
Echinococcus multilocularis mitogen activated protein kinase kinase kinase 0.0362 0.1503 0.2369
Schistosoma mansoni bromodomain containing protein 0.0076 0.0026 0.0009
Loa Loa (eye worm) PLK/PLK1 protein kinase 0.0364 0.1517 0.1501
Echinococcus granulosus calcium:calmodulin dependent protein kinase 0.018 0.0565 0.0729
Loa Loa (eye worm) hypothetical protein 0.0078 0.0035 0.0015
Entamoeba histolytica protein kinase, putative 0.0326 0.1321 0.8679
Onchocerca volvulus 0.0124 0.0272 0.1042
Echinococcus granulosus GTPase activating Rap:RanGAP domain 3 0.0107 0.0186 0.0237
Loa Loa (eye worm) hypothetical protein 0.017 0.0509 0.049
Brugia malayi Protein kinase domain containing protein 0.0323 0.1304 0.1287
Echinococcus multilocularis roundabout 2 0.0176 0.0539 0.0846
Echinococcus granulosus serine:threonine protein kinase 12 B 0.0208 0.0709 0.0916
Echinococcus granulosus c src tyrosine kinase 0.0194 0.0634 0.0819
Brugia malayi hypothetical protein 0.0286 0.111 0.1092
Trypanosoma cruzi cyclin, putative 0.024 0.0874 0.4873
Echinococcus granulosus p21 activated protein kinase 1 Dpak1 0.0108 0.0187 0.0239
Echinococcus multilocularis 5' AMP activated protein kinase catalytic 0.0188 0.0602 0.0946
Brugia malayi SH2 domain containing protein 0.0078 0.0036 0.0016
Trypanosoma brucei aurora B kinase 0.0208 0.0709 0.3644
Echinococcus granulosus 5'partial|cyclin dependent kinase 1 0.021 0.0717 0.0927
Loa Loa (eye worm) CAMK/CAMKL/NIM1 protein kinase 0.0124 0.0272 0.0253
Loa Loa (eye worm) SH2 domain-containing protein 0.0078 0.0036 0.0016
Trypanosoma cruzi Protein kinase B 0.0191 0.062 0.3446
Echinococcus multilocularis SH2 motif 0.0078 0.0036 0.0052
Loa Loa (eye worm) TTK protein kinase 0.0113 0.0218 0.0198
Leishmania major rac serine-threonine kinase, putative,protein kinase, putative 0.0132 0.0315 0.1323
Loa Loa (eye worm) hypothetical protein 0.0078 0.0036 0.0016
Echinococcus multilocularis ribosomal protein S6 kinase alpha 3 0.0257 0.0961 0.1513
Trichomonas vaginalis CAMK family protein kinase 0.0364 0.1517 0.9727
Echinococcus granulosus glycogen synthase kinase 3 beta 0.0181 0.0568 0.0733
Trypanosoma cruzi mitogen-activated protein kinase 3, putative 0.0416 0.1787 1
Echinococcus multilocularis serine:threonine protein kinase PAK 4 0.0371 0.1552 0.2446
Loa Loa (eye worm) camk/mapkapk/mapkapk protein kinase 0.057 0.2583 0.2568
Echinococcus multilocularis nicotinic acetylcholine receptor subunit alpha 8 0.017 0.0509 0.0798
Loa Loa (eye worm) CMGC/CDK/CDK5 protein kinase 0.021 0.0717 0.0699
Toxoplasma gondii protein kinase G AGC kinase family member PKG 0.0138 0.0347 0.2251
Schistosoma mansoni growth factor receptor-bound protein 0.013 0.0305 0.0452
Plasmodium falciparum serine/threonine protein kinase 0.0089 0.0091 0.0164
Echinococcus granulosus nicotinic acetylcholine receptor beta 1 subunit 0.017 0.0509 0.0656
Leishmania major protein kinase A catalytic subunit isoform 2 0.0158 0.0449 0.2111
Schistosoma mansoni hypothetical protein 0.0078 0.0036 0.0026
Echinococcus multilocularis enhancer of mRNA decapping protein 4 0.0117 0.0237 0.037
Loa Loa (eye worm) hypothetical protein 0.0137 0.0341 0.0322
Entamoeba histolytica protein kinase, putative 0.0089 0.0091 0.0597
Trichomonas vaginalis AGC family protein kinase 0.0326 0.1321 0.8433
Loa Loa (eye worm) hypothetical protein 0.0078 0.0035 0.0015
Trypanosoma cruzi developmentally regulated phosphoprotein, putative 0.0121 0.0254 0.1391
Brugia malayi Neurotransmitter-gated ion-channel transmembrane region family protein 0.017 0.0509 0.049
Schistosoma mansoni nAChR subunit (ShAR1-beta2-like) 0.017 0.0509 0.0774
Plasmodium vivax glycogen synthase kinase 3, putative 0.0181 0.0568 0.7787
Echinococcus multilocularis calcium:calmodulin dependent protein kinase type 0.0106 0.0179 0.0278
Entamoeba histolytica casein kinase, putative 0.0114 0.0218 0.1433
Loa Loa (eye worm) TK/FER protein kinase 0.0144 0.0374 0.0355
Echinococcus granulosus Serine/threonine-protein kinase Genghis Khan 0.0241 0.0879 0.1138
Echinococcus multilocularis tensin 0.0078 0.0036 0.0052
Loa Loa (eye worm) CAMK/PKD protein kinase 0.0224 0.0792 0.0774
Trypanosoma cruzi CYC2-like cyclin, putative 0.024 0.0874 0.4873
Echinococcus granulosus cyclins 0.0146 0.0385 0.0496
Trypanosoma cruzi Vacuolar sorting protein 39 domain 1/Vacuolar sorting protein 39 domain 2, putative 0.0107 0.0186 0.1008
Brugia malayi Casein kinase II, alpha chain 0.0105 0.0176 0.0156
Brugia malayi serine/threonine-protein kinase 6 0.0208 0.0709 0.0691
Echinococcus multilocularis glycogen synthase kinase 3 beta 0.0181 0.0568 0.0891
Brugia malayi ephrin receptor 1 precursor 0.0094 0.0118 0.0098
Echinococcus multilocularis p21 activated protein kinase 1 Dpak1 0.0108 0.0187 0.0291
Loa Loa (eye worm) hypothetical protein 0.0121 0.0254 0.0235
Echinococcus granulosus titin 0.0075 0.002 0.0021
Schistosoma mansoni vesicular amine transporter 0.0123 0.0269 0.0394
Brugia malayi Egg laying defective protein 4 0.0138 0.0347 0.0328
Loa Loa (eye worm) TK/EPH protein kinase 0.0144 0.0374 0.0355
Brugia malayi hypothetical protein 0.0078 0.0035 0.0015
Echinococcus granulosus serine:threonine protein kinase MARK2 0.0148 0.0398 0.0513
Echinococcus multilocularis casein kinase I alpha 0.0114 0.0218 0.0339
Echinococcus multilocularis STE20 serine:threonine protein kinase 0.0484 0.2139 0.3372
Trichomonas vaginalis CAMK family protein kinase 0.0095 0.0122 0.0521
Brugia malayi Protein kinase domain containing protein 0.044 0.1911 0.1895
Trichomonas vaginalis cyclin D, putative 0.0146 0.0385 0.2257
Brugia malayi Serine/threonine-protein kinase SULU 0.0413 0.1772 0.1755
Onchocerca volvulus Tyrosine kinase homolog 0.0564 0.2553 1
Trypanosoma brucei mitotic cyclin 6 0.024 0.0874 0.4618
Loa Loa (eye worm) hypothetical protein 0.0124 0.0273 0.0254
Trichomonas vaginalis STE family protein kinase 0.0144 0.0374 0.2181
Echinococcus granulosus gamma aminobutyric acid receptor subunit 0.0078 0.0035 0.0041
Loa Loa (eye worm) CAMK/CAMK2 protein kinase 0.0106 0.0179 0.016
Trichomonas vaginalis cyclin B, putative 0.024 0.0874 0.5483
Giardia lamblia Kinase, STE STE20 0.0108 0.0187 0.0676
Giardia lamblia Kinase, CMGC MAPK 0.0141 0.0359 0.188
Giardia lamblia Kinase, CDC7 0.0209 0.0715 0.4374
Loa Loa (eye worm) nicotinic acetylcholine receptor non-alpha subunit 0.017 0.0509 0.049
Trypanosoma cruzi cyclin 6, putative 0.024 0.0874 0.4873
Echinococcus multilocularis tyrosine protein kinase Srms 0.0228 0.0812 0.1277
Echinococcus multilocularis 0.0459 0.2007 0.3163
Echinococcus multilocularis SH2 motif 0.0078 0.0036 0.0052
Echinococcus multilocularis cyclin dependent kinase 1 0.021 0.0717 0.1127
Schistosoma mansoni serine/threonine protein kinase 0.0114 0.0218 0.0314
Echinococcus multilocularis nicotinic acetylcholine receptor beta 1 subunit 0.017 0.0509 0.0798
Schistosoma mansoni serine/threonine protein kinase 0.0204 0.0686 0.1055
Brugia malayi SH2 domain containing protein 0.0078 0.0036 0.0016
Echinococcus granulosus cGMP dependent protein kinase 0.0138 0.0347 0.0447
Schistosoma mansoni tyrosine kinase 0.0892 0.4252 0.67
Loa Loa (eye worm) TK/KIN16 protein kinase 0.0681 0.316 0.3146
Echinococcus granulosus NDR protein kinase 0.0176 0.0542 0.07
Loa Loa (eye worm) hypothetical protein 0.0107 0.0186 0.0167
Loa Loa (eye worm) hypothetical protein 0.0128 0.0295 0.0276
Loa Loa (eye worm) TK protein kinase 0.038 0.1597 0.158
Brugia malayi Protein kinase domain containing protein 0.0144 0.0374 0.0355
Trypanosoma cruzi cyclin, putative 0.024 0.0874 0.4873
Schistosoma mansoni rap gtpase-activating protein 0.0107 0.0186 0.0263
Brugia malayi SH2 domain containing protein 0.0144 0.0374 0.0355
Trichomonas vaginalis CAMK family protein kinase 0.0364 0.1517 0.9727
Echinococcus multilocularis serine:threonine protein kinase PLK1 0.0364 0.1517 0.239
Schistosoma mansoni serine/threonine-protein kinase 0.0191 0.062 0.095
Echinococcus multilocularis tyrosine protein kinase Fgr 0.0278 0.1072 0.1687
Echinococcus multilocularis tyrosine protein kinase lyn tyrosine protein kinase blk 0.0278 0.1072 0.1687
Trichomonas vaginalis STE family protein kinase 0.0108 0.0187 0.095
Loa Loa (eye worm) AGC/AKT protein kinase 0.0326 0.1321 0.1304
Echinococcus multilocularis mitogen activated protein kinase 14 0.0416 0.1787 0.2816
Loa Loa (eye worm) hypothetical protein 0.0078 0.0035 0.0015
Schistosoma mansoni serine/threonine protein kinase 0.0241 0.0879 0.1361
Onchocerca volvulus 0.0144 0.0374 0.1444
Loa Loa (eye worm) TK protein kinase 0.0357 0.1478 0.1462
Loa Loa (eye worm) CMGC/DYRK/HIPK protein kinase 0.0204 0.0686 0.0668
Echinococcus multilocularis serine threonine protein kinase 0.0257 0.096 0.151
Loa Loa (eye worm) cytokine inducible SH2-containing protein 5 0.0078 0.0036 0.0016
Loa Loa (eye worm) hypothetical protein 0.0078 0.0035 0.0015
Echinococcus multilocularis tyrosine protein kinase HCK 0.015 0.0406 0.0635
Echinococcus multilocularis cyclins 0.0146 0.0385 0.0603
Echinococcus multilocularis Immunoglobulin 0.0123 0.0269 0.0419
Entamoeba histolytica protein kinase, putative 0.0119 0.0248 0.1628
Loa Loa (eye worm) hypothetical protein 0.2001 1 1
Loa Loa (eye worm) CK1/CK1/CK1-A protein kinase 0.0114 0.0218 0.0199
Trypanosoma cruzi casein kinase, putative 0.0114 0.0218 0.1189
Plasmodium vivax serine/threonine protein kinase, putative 0.0089 0.0091 0.0716
Echinococcus multilocularis tyrosine protein kinase Fyn 0.0278 0.1072 0.1687
Echinococcus granulosus cyclin dependent kinase 0.021 0.0717 0.0927
Schistosoma mansoni serine/threonine protein kinase 0.0167 0.0494 0.0751
Onchocerca volvulus 0.0137 0.0341 0.1313
Brugia malayi Protein kinase domain containing protein 0.0113 0.0218 0.0198
Echinococcus multilocularis tyrosine protein kinase lyn lyn a protein tyrosine kinase lymphocyte specific protein tyrosine kinase 0.0278 0.1072 0.1687
Echinococcus multilocularis casein kinase i 0.0114 0.0218 0.0339
Leishmania major protein kinase, putative 0.0091 0.0099 0.0046
Schistosoma mansoni acetylcholine receptor subunit beta 0.0078 0.0035 0.0024
Schistosoma mansoni tyrosine kinase 0.0779 0.3667 0.5773
Brugia malayi Protein kinase domain containing protein 0.0144 0.0374 0.0355
Schistosoma mansoni serine/threonine protein kinase 0.0161 0.0465 0.0705
Brugia malayi nicotinic acetylcholine receptor alpha subunit, putative 0.017 0.0509 0.049
Loa Loa (eye worm) GABA receptor subunit 0.0091 0.0103 0.0084
Onchocerca volvulus 0.0078 0.0036 0.0116
Echinococcus multilocularis fibroblast growth factor receptor 4 0.0356 0.1472 0.232
Schistosoma mansoni serine/threonine protein kinase 0.0148 0.0398 0.06
Echinococcus granulosus 3-phosphoinositide-dependent protein kinase 1 0.0087 0.0083 0.0103
Toxoplasma gondii AGC kinase 0.0316 0.1266 1
Entamoeba histolytica protein kinase , putative 0.0208 0.0709 0.4657
Brugia malayi Temporarily assigned gene name protein 59 0.0124 0.0272 0.0253
Toxoplasma gondii calcium dependent protein kinase CDPK8 0.0106 0.0179 0.0833
Loa Loa (eye worm) hypothetical protein 0.0259 0.0973 0.0955
Echinococcus multilocularis maternal embryonic leucine zipper kinase 0.012 0.025 0.039
Schistosoma mansoni nAChR subunit 0.017 0.0509 0.0774
Echinococcus granulosus tyrosine kinase|tyrosine protein kinase Fyn 0.0228 0.0812 0.1051
Loa Loa (eye worm) hypothetical protein 0.0078 0.0036 0.0016
Schistosoma mansoni protein kinase 0.0105 0.0176 0.0247
Schistosoma mansoni protein kinase 0.0208 0.0709 0.1091
Schistosoma mansoni serine/threonine protein kinase 0.0241 0.0879 0.1361
Trichomonas vaginalis CAMK family protein kinase 0.0095 0.0122 0.0521
Trichomonas vaginalis CK1 family protein kinase 0.0114 0.0218 0.1154
Echinococcus multilocularis rho associated protein kinase 0.0322 0.1296 0.2041
Plasmodium vivax rac-beta serine/threonine protein kinase, putative 0.018 0.0565 0.7742
Loa Loa (eye worm) hypothetical protein 0.017 0.0509 0.049
Trichomonas vaginalis CK1 family protein kinase 0.0114 0.0218 0.1154
Trichomonas vaginalis CMGC family protein kinase 0.0143 0.0369 0.2151
Loa Loa (eye worm) hypothetical protein 0.0586 0.2665 0.265
Schistosoma mansoni nAChR subunit (ShAR1-beta-like) 0.017 0.0509 0.0774
Echinococcus multilocularis suppressor of cytokine signaling 7 0.0078 0.0036 0.0052
Echinococcus multilocularis cyclin dependent kinase 5 activator 1 0.0259 0.0973 0.1531
Trichomonas vaginalis CAMK family protein kinase 0.012 0.025 0.1365
Echinococcus granulosus ribosomal protein s6 kinase beta 1 0.0176 0.0542 0.07
Echinococcus granulosus growth factor receptor bound protein 2 0.013 0.0305 0.0393
Schistosoma mansoni tensin-related 0.0078 0.0036 0.0026
Loa Loa (eye worm) hypothetical protein 0.037 0.1547 0.153
Echinococcus multilocularis Ribosomal protein S6 kinase beta 2 0.0176 0.0542 0.0851
Echinococcus multilocularis raf serine:threonine protein kinase 0.0112 0.0208 0.0323
Loa Loa (eye worm) protein-tyrosine phosphatase 0.0078 0.0036 0.0016
Loa Loa (eye worm) hypothetical protein 0.0091 0.0103 0.0084
Schistosoma mansoni protein kinase 0.0231 0.0829 0.1282
Echinococcus granulosus suppressor of cytokine signaling 7 0.0078 0.0036 0.0043
Loa Loa (eye worm) hypothetical protein 0.017 0.0509 0.049
Brugia malayi Neuronal acetylcholine receptor protein, alpha-2 chain precursor 0.0078 0.0035 0.0015
Entamoeba histolytica protein kinase, putative 0.0326 0.1321 0.8679
Echinococcus multilocularis suppressor of cytokine signaling 7 0.0078 0.0036 0.0052
Echinococcus multilocularis epidermal growth factor receptor 0.1294 0.6337 1
Schistosoma mansoni protein kinase 0.0194 0.0637 0.0978
Schistosoma mansoni serine/threonine protein kinase 0.0148 0.0398 0.06
Trichomonas vaginalis STE family protein kinase 0.0108 0.0187 0.095
Leishmania major protein kinase A catalytic subunit isoform 1 0.0158 0.0449 0.2111
Trichomonas vaginalis AGC family protein kinase 0.0326 0.1321 0.8433
Schistosoma mansoni cyclin B3 0.0258 0.0969 0.1503
Trichomonas vaginalis CMGC family protein kinase 0.021 0.0717 0.4445
Brugia malayi cyclin-dependent kinase 9 0.0086 0.0077 0.0057
Schistosoma mansoni protein kinase 0.0264 0.0996 0.1546
Loa Loa (eye worm) STAT protein 0.0078 0.0036 0.0016
Schistosoma mansoni serine/threonine protein kinase 0.021 0.0717 0.1104
Echinococcus multilocularis Pyruvate dehydrogenase (lipoamide) kinase 0.0121 0.0254 0.0396
Loa Loa (eye worm) hypothetical protein 0.0133 0.0321 0.0302
Echinococcus granulosus neuroglian 0.0147 0.0393 0.0507
Loa Loa (eye worm) hypothetical protein 0.017 0.0509 0.049
Onchocerca volvulus 0.0194 0.0636 0.2473
Echinococcus multilocularis cAMP dependent protein kinase catalytic subunit 0.0158 0.0449 0.0704
Echinococcus granulosus tyrosine protein kinase shark 0.0779 0.3667 0.4758
Loa Loa (eye worm) hypothetical protein 0.017 0.0509 0.049
Toxoplasma gondii cell-cycle-associated protein kinase GSK, putative 0.0181 0.0568 0.411
Echinococcus granulosus cAMP dependent protein kinase catalytic subunit 0.0158 0.0449 0.0579
Leishmania major protein kinase A catalytic subunit 0.0158 0.0449 0.2111
Echinococcus multilocularis tyrosine protein kinase Fps85D 0.0435 0.1885 0.2971
Schistosoma mansoni protein kinase 0.0231 0.0829 0.1282
Trichomonas vaginalis CMGC family protein kinase 0.0209 0.0715 0.4432
Onchocerca volvulus 0.0475 0.209 0.8184
Loa Loa (eye worm) CMGC/SRPK protein kinase 0.0089 0.0091 0.0071
Brugia malayi Neurotransmitter-gated ion-channel ligand binding domain containing protein 0.017 0.0509 0.049
Trichomonas vaginalis CAMK family protein kinase 0.0095 0.0122 0.0521
Onchocerca volvulus 0.0091 0.0101 0.037
Loa Loa (eye worm) TK/FER protein kinase 0.0144 0.0374 0.0355
Echinococcus granulosus guanine nucleotide exchange factor VAV2 0.0125 0.0276 0.0354
Trichomonas vaginalis AGC family protein kinase 0.014 0.0355 0.2057
Echinococcus multilocularis expressed protein 0.0089 0.0091 0.0139
Schistosoma mansoni mitogen-activated protein kinase kinase kinase 3 mapkkk3 mekk3 0.0107 0.0186 0.0263
Trichomonas vaginalis AGC family protein kinase 0.0326 0.1321 0.8433
Echinococcus granulosus SH2 motif 0.0078 0.0036 0.0043
Echinococcus granulosus NCK adaptor protein 0.0128 0.0295 0.038
Echinococcus multilocularis casein kinase I alpha 0.0114 0.0218 0.0339
Trichomonas vaginalis CAMK family protein kinase 0.0178 0.055 0.3346
Schistosoma mansoni serine/threonine protein kinase 0.0106 0.0179 0.0253
Schistosoma mansoni tyrosine kinase 0.0819 0.3875 0.6104
Loa Loa (eye worm) STE/STE20/YSK protein kinase 0.0144 0.0374 0.0355
Brugia malayi casein kinase 1, delta 0.0114 0.0218 0.0199
Echinococcus granulosus G2:mitotic specific cyclin B3 0.0258 0.0969 0.1255
Schistosoma mansoni proto-oncogene tyrosine-protein kinase src 0.0194 0.0634 0.0972
Toxoplasma gondii calcium-dependent protein kinase CDPK2B 0.0106 0.0179 0.0833
Echinococcus multilocularis SHC transforming protein 3 0.0078 0.0036 0.0052
Brugia malayi P38 map kinase family protein 2 0.0416 0.1787 0.1771
Plasmodium falciparum serine/threonine protein kinase KIN 0.0095 0.0122 0.0657
Echinococcus granulosus Immunoglobulin 0.0123 0.0269 0.0345
Leishmania major protein kinase, putative,dual-specificity protein kinase, putative 0.0143 0.0369 0.1641
Echinococcus multilocularis tyrosine protein kinase Btk29A 0.045 0.1962 0.3093
Echinococcus granulosus cGMP dependent protein kinase 1 0.0138 0.0347 0.0447
Schistosoma mansoni tyrosine kinase 0.07 0.326 0.513
Echinococcus multilocularis nervana 2 0.014 0.0353 0.0552
Schistosoma mansoni nAChR subunit 0.0078 0.0035 0.0024
Loa Loa (eye worm) CMGC/GSK protein kinase 0.0181 0.0568 0.0549
Schistosoma mansoni nck2/grb4 0.0128 0.0295 0.0437
Echinococcus multilocularis cAMP dependent protein kinase catalytic subunit 0.0158 0.0449 0.0704
Schistosoma mansoni tyrosine kinase 0.0194 0.0634 0.0972
Trypanosoma cruzi cAMP-dependent protein kinase catalytic subunit 2 0.0158 0.0449 0.2485
Entamoeba histolytica protein kinase domain containing protein 0.0143 0.0369 0.2425
Brugia malayi Protein kinase domain containing protein 0.0509 0.2267 0.2252
Loa Loa (eye worm) sex muscle abnormal protein 5 0.0128 0.0295 0.0276
Echinococcus multilocularis cAMP dependent protein kinase catalytic subunit 0.0158 0.0449 0.0704
Loa Loa (eye worm) STE/STE20/MST protein kinase 0.0256 0.0956 0.0938
Schistosoma mansoni serine/threonine protein kinase 0.0158 0.0449 0.068
Trichomonas vaginalis AGC family protein kinase 0.0176 0.0542 0.3294
Giardia lamblia Kinase, AGC PKA 0.018 0.0565 0.3321
Entamoeba histolytica protein kinase, putative 0.0087 0.0083 0.0544
Trichomonas vaginalis CAMK family protein kinase 0.0113 0.0218 0.115
Onchocerca volvulus 0.0075 0.002 0.0052
Echinococcus granulosus mitogen activated protein kinase kinase kinase 0.0362 0.1503 0.1948
Chlamydia trachomatis serine/threonine protein kinase 0.025 0.0923 0.5
Trypanosoma cruzi STE/STE11 serine/threonine-protein kinase, putative 0.0106 0.0179 0.0971
Echinococcus granulosus phosphatidylinositol 3 kinase regulatory subunit 0.0078 0.0036 0.0043
Echinococcus granulosus casein kinase I gamma 0.0214 0.0739 0.0956
Echinococcus granulosus serine:threonine protein kinase N2 0.0125 0.0275 0.0353
Trichomonas vaginalis STE family protein kinase 0.0091 0.0099 0.0365
Loa Loa (eye worm) protein kinase domain-containing protein 0.0214 0.0739 0.0721
Schistosoma mansoni nicotinic acetylcholine receptor alpha 0.0091 0.0103 0.0132
Schistosoma mansoni tyrosine kinase 0.0892 0.4252 0.67
Echinococcus granulosus nervana 2 0.014 0.0353 0.0454
Loa Loa (eye worm) SRC-1 0.0278 0.1072 0.1054
Echinococcus granulosus serine:threonine protein kinase PLK1 0.0364 0.1517 0.1966
Schistosoma mansoni serine/threonine protein kinase 0.0109 0.0196 0.028
Loa Loa (eye worm) glutamate-gated chloride channel alpha3A subunit 0.0078 0.0035 0.0015
Entamoeba histolytica protein kinase domain containing protein 0.0181 0.0568 0.373
Echinococcus multilocularis death associated protein kinase 1 0.0824 0.3902 0.6155
Schistosoma mansoni serine/threonine protein kinase 0.025 0.0923 0.143
Leishmania major glycogen synthase kinase, putative;with=GeneDB:LinJ18_V3.0270 0.0181 0.0568 0.2811
Giardia lamblia Kinase, NEK 0.014 0.0355 0.1852
Echinococcus granulosus nAChR subunit 0.017 0.0509 0.0656
Trichomonas vaginalis AGC family protein kinase 0.0326 0.1321 0.8433
Echinococcus multilocularis Glutaredoxin protein 5 0.014 0.0353 0.0552
Schistosoma mansoni serine/threonine protein kinase 0.0176 0.0542 0.0828
Brugia malayi Cyclin, N-terminal domain containing protein 0.024 0.0874 0.0856
Loa Loa (eye worm) CAMK/TSSK protein kinase 0.0586 0.2665 0.265
Loa Loa (eye worm) hypothetical protein 0.017 0.0509 0.049
Echinococcus multilocularis suppressor of cytokine signaling 6 0.0078 0.0036 0.0052
Loa Loa (eye worm) acetylcholine receptor protein 0.0078 0.0035 0.0015
Echinococcus multilocularis calcium:calmodulin dependent protein kinase I 0.0077 0.003 0.0042
Plasmodium falciparum RAC-beta serine/threonine protein kinase 0.018 0.0565 0.7608
Brugia malayi Hypothetical glycine receptor like protein T20B12.9 in chromosome III 0.017 0.0509 0.049
Trypanosoma brucei 5'-AMP-activated protein kinase catalytic subunit alpha, putative 0.0095 0.0122 0.0185
Trichomonas vaginalis AGC family protein kinase 0.0208 0.0709 0.4392
Schistosoma mansoni vam6/vps39 related 0.0107 0.0186 0.0263
Schistosoma mansoni serine/threonine protein kinase 0.0077 0.003 0.0016
Entamoeba histolytica casein kinase, putative 0.0105 0.0176 0.1154
Loa Loa (eye worm) AGC/RSK/P70 protein kinase 0.0316 0.1266 0.1249
Brugia malayi Protein kinase domain containing protein 0.0892 0.4252 0.4241
Loa Loa (eye worm) CAMK/CAMKL/BRSK protein kinase 0.0095 0.0122 0.0103
Trypanosoma cruzi mitogen activated protein kinase 2, putative 0.0141 0.0359 0.1981
Schistosoma mansoni protein kinase 0.0426 0.1838 0.2878
Echinococcus multilocularis dual specificity 0.0143 0.0369 0.0578
Brugia malayi hypothetical protein 0.0078 0.0036 0.0016
Trichomonas vaginalis CAMK family protein kinase 0.0106 0.0179 0.0897
Loa Loa (eye worm) hypothetical protein 0.0078 0.0036 0.0016
Trypanosoma cruzi polo-like protein kinase, putative 0.0364 0.1517 0.8486
Plasmodium falciparum cGMP-dependent protein kinase 0.0138 0.0347 0.4193
Loa Loa (eye worm) AGC/PDK1 protein kinase 0.0095 0.0124 0.0105
Trichomonas vaginalis STE family protein kinase 0.0108 0.0187 0.095
Echinococcus granulosus serine:threonine protein kinase PAK 3 0.0108 0.0187 0.0239
Trichomonas vaginalis CK1 family protein kinase 0.0114 0.0218 0.1154
Schistosoma mansoni serine/threonine protein kinase 0.0138 0.0347 0.0519
Trichomonas vaginalis CAMK family protein kinase 0.0095 0.0122 0.0521
Trichomonas vaginalis AGC family protein kinase 0.0087 0.0083 0.0261
Echinococcus granulosus signal transduction protein lnk realted 0.0078 0.0036 0.0043
Giardia lamblia Aurora kinase 0.0208 0.0709 0.4332
Echinococcus granulosus phosphorylase kinase gamma subunit 0.0167 0.0494 0.0638
Echinococcus granulosus cyclins 0.0146 0.0385 0.0496
Echinococcus multilocularis tyrosine kinase 0.0144 0.0374 0.0586
Echinococcus granulosus calcium:calmodulin dependent protein kinase I 0.0077 0.003 0.0035
Trypanosoma brucei mitogen-activated protein kinase 3, putative 0.0416 0.1787 1
Schistosoma mansoni serine/threonine protein kinase 0.0124 0.0272 0.0399
Loa Loa (eye worm) hypothetical protein 0.0194 0.0636 0.0618
Echinococcus granulosus casein kinase i 0.0114 0.0218 0.0279
Schistosoma mansoni tyrosine kinase 0.0278 0.1072 0.1665
Toxoplasma gondii cell-cycle-associated protein kinase DYRK2, putative 0.0143 0.0369 0.2435
Loa Loa (eye worm) hypothetical protein 0.017 0.0509 0.049
Loa Loa (eye worm) TK/FER protein kinase 0.0144 0.0374 0.0355
Schistosoma mansoni tyrosine kinase 0.0194 0.0634 0.0972
Schistosoma mansoni serine/threonine protein kinase 0.0208 0.0709 0.1091
Brugia malayi Protein kinase domain containing protein 0.0201 0.0674 0.0655
Echinococcus multilocularis tyrosine protein kinase Fyn 0.0228 0.0812 0.1277
Schistosoma mansoni ste20-related kinase 0.0206 0.0699 0.1075
Brugia malayi hypothetical protein 0.0124 0.0273 0.0254
Trichomonas vaginalis cyclins, putative 0.0146 0.0385 0.2257
Trichomonas vaginalis CAMK family protein kinase 0.0095 0.0122 0.0521
Echinococcus granulosus calcium activated potassium channel 0.0109 0.0196 0.0251
Echinococcus granulosus cyclin dependent kinase 1 0.021 0.0717 0.0927
Schistosoma mansoni nAChR subunit 0.017 0.0509 0.0774
Schistosoma mansoni serine/threonine kinase 0.0196 0.0647 0.0993
Loa Loa (eye worm) STE/STE20/TAO protein kinase 0.0413 0.1772 0.1755
Schistosoma mansoni Cys-loop ligand gated ion channel subunit 0.017 0.0509 0.0774
Schistosoma mansoni serine/threonine protein kinase 0.0254 0.0947 0.1468
Trichomonas vaginalis STE family protein kinase 0.0108 0.0187 0.095
Loa Loa (eye worm) hypothetical protein 0.0292 0.1143 0.1126
Echinococcus granulosus glycine receptor subunit alpha 1 0.017 0.0509 0.0656
Leishmania major casein kinase II, putative 0.0105 0.0176 0.0499
Echinococcus granulosus tensin C1 domain containing phosphatase 0.0078 0.0036 0.0043
Echinococcus multilocularis casein kinase I delta 0.0114 0.0218 0.0339
Brugia malayi Cation transporter family protein 0.017 0.0509 0.049
Loa Loa (eye worm) variant SH3 domain-containing protein 0.0128 0.0295 0.0276
Plasmodium vivax calcium-dependent protein kinase 3, putative 0.0106 0.0179 0.2026
Entamoeba histolytica protein kinase, putative 0.0208 0.0709 0.4657
Trichomonas vaginalis CAMK family protein kinase 0.0372 0.1559 1
Entamoeba histolytica PH domain containing protein kinase, putative 0.0191 0.062 0.4073
Loa Loa (eye worm) hypothetical protein 0.0443 0.1927 0.1911
Trypanosoma cruzi rac serine-threonine kinase, putative 0.0191 0.062 0.3446
Loa Loa (eye worm) hypothetical protein 0.0286 0.111 0.1092
Loa Loa (eye worm) STE/STE20/KHS protein kinase 0.0362 0.1503 0.1487
Echinococcus multilocularis MAP kinase activated protein kinase 2 0.057 0.2583 0.4073
Trypanosoma cruzi cdc2-related kinase 1 0.021 0.0717 0.399
Echinococcus granulosus survival motor neuron protein 1 0.0286 0.111 0.1437
Trichomonas vaginalis CMGC family protein kinase 0.0105 0.0176 0.0873
Echinococcus granulosus cyclin dependent kinase 9 0.0094 0.0118 0.0149
Echinococcus granulosus 3'partial|tyrosine protein kinase Fgr 0.0278 0.1072 0.1387
Trichomonas vaginalis cyclins, putative 0.024 0.0874 0.5483
Brugia malayi Protein kinase domain 0.0108 0.0187 0.0168
Onchocerca volvulus 0.0144 0.0374 0.1444
Echinococcus multilocularis calcium:calmodulin dependent protein kinase type 0.0106 0.0179 0.0278
Trypanosoma brucei protein kinase, putative 0.0106 0.0179 0.0521
Echinococcus multilocularis tyrosine protein kinase Src42A 0.0165 0.0484 0.0759
Brugia malayi Serine/threonine-protein kinase Pim-3 0.0509 0.2267 0.2252
Giardia lamblia Kinase, CAMK CAMKL 0.0103 0.0164 0.0509
Loa Loa (eye worm) hypothetical protein 0.0283 0.1094 0.1076
Brugia malayi Temporarily assigned gene name protein 59 0.0107 0.0186 0.0167
Echinococcus granulosus mitogen activated protein kinase 11 0.0416 0.1787 0.2316
Entamoeba histolytica protein kinase, putative 0.0108 0.0187 0.123
Schistosoma mansoni Neurotrimin precursor (hNT) 0.0123 0.0269 0.0394
Echinococcus multilocularis tyrosine protein kinase shark 0.0779 0.3667 0.5784
Schistosoma mansoni serine/threonine protein kinase 0.0303 0.12 0.1868
Brugia malayi C1-like domain containing protein 0.0224 0.0792 0.0774
Toxoplasma gondii hypothetical protein 0.0106 0.0177 0.0817
Echinococcus granulosus serine threonine protein kinase nrc 0.018 0.0565 0.0729
Giardia lamblia Kinase, CAMK CAMKL 0.0103 0.0164 0.0509
Schistosoma mansoni suppressor of cytokine signaling 0.0078 0.0036 0.0026
Echinococcus granulosus serine:threonine protein kinase 3 0.0256 0.0956 0.1237
Leishmania major protein kinase, putative 0.0106 0.0179 0.0521
Echinococcus granulosus glycine receptor subunit alpha 1 0.017 0.0509 0.0656
Onchocerca volvulus Dual specificity protein kinase TTK homolog 0.0113 0.0218 0.0829
Trichomonas vaginalis CMGC family protein kinase 0.0105 0.0176 0.0873
Echinococcus granulosus cyclin b3 0.0146 0.0385 0.0496
Echinococcus granulosus cyclin dependent kinase 5 activator 1 0.0259 0.0973 0.1259
Echinococcus granulosus serine:threonine protein kinase TAO1 0.0413 0.1772 0.2297
Trypanosoma brucei Vacuolar sorting protein 39 domain 1/Vacuolar sorting protein 39 domain 2, putative 0.0107 0.0186 0.056
Trichomonas vaginalis CMGC family protein kinase 0.0141 0.0359 0.2084
Schistosoma mansoni Cys-loop ligand gated ion channel subunit 0.0091 0.0103 0.0132
Echinococcus multilocularis tyrosine protein kinase Src64B 0.0278 0.1072 0.1687
Onchocerca volvulus 0.0209 0.0715 0.2782
Echinococcus multilocularis phosphatidylinositol 3 kinase regulatory subunit 0.0078 0.0036 0.0052
Brugia malayi Sex muscle abnormal protein 5 0.0128 0.0295 0.0276
Echinococcus granulosus calcium:calmodulin dependent protein kinase type 0.0106 0.0179 0.0229
Echinococcus multilocularis calcium activated potassium channel 0.0109 0.0196 0.0305
Echinococcus multilocularis calcium:calmodulin dependent protein kinase type 0.0106 0.0179 0.0278
Toxoplasma gondii casein kinase I 0.0114 0.0218 0.1162
Loa Loa (eye worm) AGC/PDK1 protein kinase 0.0087 0.0083 0.0063
Echinococcus multilocularis PAK box P21 Rho binding 0.0087 0.0079 0.012
Onchocerca volvulus 0.0144 0.0374 0.1444
Loa Loa (eye worm) hypothetical protein 0.0091 0.0103 0.0084
Echinococcus multilocularis survival motor neuron protein 1 0.0286 0.111 0.1747
Echinococcus granulosus homeodomain interacting protein kinase 3 0.0204 0.0686 0.0887
Onchocerca volvulus 0.024 0.0874 0.3408
Schistosoma mansoni serine/threonine protein kinase 0.0303 0.12 0.1868
Schistosoma mansoni protein kinase 0.0087 0.0079 0.0094
Loa Loa (eye worm) SH2 domain-containing protein 0.0078 0.0036 0.0016
Entamoeba histolytica hypothetical protein 0.0091 0.0103 0.0677
Schistosoma mansoni protein kinase 0.0108 0.0187 0.0265
Trypanosoma brucei calcium/calmodulin-dependent protein kinase, putative 0.0106 0.0179 0.0521
Echinococcus granulosus cyclin dependent kinase 5 0.021 0.0717 0.0927
Loa Loa (eye worm) AGC/PKC/IOTA protein kinase 0.0173 0.0524 0.0506
Trichomonas vaginalis CMGC family protein kinase 0.0105 0.0176 0.0873
Brugia malayi Cation transporter family protein 0.017 0.0509 0.049
Loa Loa (eye worm) hypothetical protein 0.0078 0.0036 0.0016
Schistosoma mansoni serine/threonine-protein kinase 0.0191 0.062 0.095
Brugia malayi Tyrosine-protein kinase abl-1 0.035 0.1442 0.1426
Loa Loa (eye worm) AGC/NDR protein kinase 0.0176 0.0542 0.0524
Trichomonas vaginalis AGC family protein kinase 0.0208 0.0709 0.4392
Loa Loa (eye worm) hypothetical protein 0.0078 0.0035 0.0015
Entamoeba histolytica serine/threonine protein kinase, putative 0.0095 0.0122 0.0803
Brugia malayi cell division control protein 2 homolog 0.0124 0.0272 0.0253
Echinococcus granulosus cyclins 0.0146 0.0385 0.0496
Entamoeba histolytica protein kinase domain containing protein 0.0105 0.0176 0.1154
Schistosoma mansoni atypical protein kinase C 0.0308 0.1225 0.1909
Brugia malayi Fibronectin type III domain containing protein 0.0134 0.0323 0.0304
Schistosoma mansoni proto-oncogene tyrosine-protein kinase abl1 0.0128 0.0295 0.0437
Trypanosoma brucei developmentally regulated phosphoprotein 0.0121 0.0254 0.0963
Echinococcus multilocularis signal transduction protein lnk realted 0.0078 0.0036 0.0052
Loa Loa (eye worm) STE/STE20/PAKB protein kinase 0.0417 0.1791 0.1774
Loa Loa (eye worm) TK/FER protein kinase 0.0435 0.1885 0.1869
Loa Loa (eye worm) hypothetical protein 0.0169 0.0505 0.0486
Brugia malayi Immunoglobulin I-set domain containing protein 0.0134 0.0323 0.0304
Leishmania major developmentally regulated phosphoprotein-like protein 0.0121 0.0254 0.0963
Brugia malayi phosphoinositide-dependent protein kinase I 0.0087 0.0083 0.0063
Loa Loa (eye worm) AUR protein kinase 0.0208 0.0709 0.0691
Loa Loa (eye worm) hypothetical protein 0.0124 0.0273 0.0254
Loa Loa (eye worm) CAMK/PIM protein kinase 0.0509 0.2267 0.2252
Echinococcus granulosus calcium:calmodulin dependent protein kinase type 0.0426 0.1838 0.2383
Echinococcus multilocularis SH2 domain containing protein 7 0.0078 0.0036 0.0052
Loa Loa (eye worm) hypothetical protein 0.0221 0.0776 0.0758
Echinococcus multilocularis RNA directed DNA polymerase 0.0078 0.0034 0.0049
Loa Loa (eye worm) hypothetical protein 0.0089 0.0091 0.0072
Brugia malayi SRC-1 0.0278 0.1072 0.1054
Echinococcus granulosus serine/threonine protein kinase 0.0191 0.062 0.0801
Trypanosoma brucei casein kinase I, isoform 2 0.0114 0.0218 0.075
Echinococcus granulosus SH2 domain containing adapter protein F 0.0078 0.0036 0.0043
Loa Loa (eye worm) CK1/CK1/CK1-A protein kinase 0.0114 0.0218 0.0199
Trypanosoma cruzi cAMP-dependent protein kinase catalytic subunit 3 0.0158 0.0449 0.2485
Entamoeba histolytica protein kinase, putative 0.0106 0.0179 0.1178
Echinococcus granulosus protein kinase 0.0156 0.044 0.0567
Leishmania major cell division protein kinase 2,cdc2-related kinase 0.021 0.0717 0.3691
Echinococcus granulosus tyrosine protein kinase Btk29A 0.045 0.1962 0.2544
Loa Loa (eye worm) hypothetical protein 0.0091 0.0103 0.0084
Loa Loa (eye worm) cyclin domain-containing protein 0.0258 0.0969 0.0952
Echinococcus granulosus SH2 motif 0.0078 0.0036 0.0043
Echinococcus multilocularis tyrosine protein kinase Blk 0.0228 0.0812 0.1277
Brugia malayi Protein kinase domain containing protein 0.0362 0.1503 0.1487
Brugia malayi Neurotransmitter-gated ion-channel transmembrane region family protein 0.017 0.0509 0.049
Echinococcus multilocularis cyclin b3 0.0146 0.0385 0.0603
Schistosoma mansoni serine/threonine protein kinase 0.0086 0.0077 0.009
Echinococcus multilocularis serine:threonine protein kinase 0.008 0.0043 0.0063
Trypanosoma cruzi cAMP-dependent protein kinase catalytic subunit 3 0.0158 0.0449 0.2485
Trypanosoma cruzi mitogen-activated protein kinase 11, putative 0.0141 0.0359 0.1981
Trypanosoma cruzi mitogen-activated protein kinase 11, putative 0.0141 0.0359 0.1981
Loa Loa (eye worm) hypothetical protein 0.0094 0.0118 0.0099
Schistosoma mansoni nAChR subunit 0.017 0.0509 0.0774
Echinococcus granulosus tensin 0.0078 0.0036 0.0043
Mycobacterium ulcerans hypothetical protein 0.0098 0.0136 0.5
Entamoeba histolytica protein kinase, putative 0.015 0.0406 0.2665
Echinococcus multilocularis calcium:calmodulin dependent protein kinase type 0.0426 0.1838 0.2897
Schistosoma mansoni hypothetical protein 0.0107 0.0186 0.0263
Brugia malayi Protein kinase domain containing protein 0.0231 0.0829 0.0811
Entamoeba histolytica protein kinase, putative 0.0077 0.003 0.0196
Brugia malayi Protein kinase domain containing protein 0.0586 0.2665 0.265
Loa Loa (eye worm) STE/STE20/SLK protein kinase 0.0194 0.0637 0.0619
Brugia malayi Protein kinase domain containing protein 0.0914 0.4368 0.4357
Plasmodium falciparum glycogen synthase kinase 3 0.0181 0.0568 0.7656
Brugia malayi cytokine inducible SH2-containing protein 5 0.0078 0.0036 0.0016
Schistosoma mansoni nAChR subunit 0.017 0.0509 0.0774
Echinococcus multilocularis mitogen activated protein kinase 14 0.0416 0.1787 0.2816
Brugia malayi Protein kinase domain containing protein 0.0507 0.2256 0.2241
Echinococcus granulosus protein tyrosine kinase 0.032 0.1289 0.167
Echinococcus granulosus tyrosine protein kinase Srms 0.0535 0.2404 0.3118
Brugia malayi hypothetical protein 0.0078 0.0035 0.0015
Leishmania major protein kinase, putative,SNF1-related protein kinases, putative 0.0095 0.0122 0.0185
Brugia malayi serine/threonine-protein kinase PAK 7 0.0417 0.1791 0.1774
Echinococcus multilocularis SH2 domain containing adapter protein F 0.0078 0.0036 0.0052
Echinococcus granulosus tyrosine protein kinase Src42A 0.0278 0.1072 0.1387
Brugia malayi SH2 domain containing protein 0.0078 0.0036 0.0016
Echinococcus granulosus casein kinase I alpha 0.0114 0.0218 0.0279
Loa Loa (eye worm) thyroid receptor interactor 0.0123 0.0267 0.0248
Trichomonas vaginalis AGC family protein kinase 0.0326 0.1321 0.8433
Schistosoma mansoni shc transforming protein 0.0078 0.0036 0.0026
Onchocerca volvulus 0.0507 0.2256 0.8837
Schistosoma mansoni nAChR subunit 0.017 0.0509 0.0774
Entamoeba histolytica p21-activated kinase 0.0118 0.0243 0.1594
Entamoeba histolytica protein kinase, putative 0.0077 0.003 0.0196
Onchocerca volvulus 0.0078 0.0036 0.0116
Echinococcus granulosus tyrosine protein kinase Src64B 0.0278 0.1072 0.1387
Loa Loa (eye worm) hypothetical protein 0.0078 0.0036 0.0016
Onchocerca volvulus 0.0078 0.0036 0.0116
Schistosoma mansoni protein kinase 0.0362 0.1503 0.2349
Trypanosoma brucei SNF1-related protein kinases, putative 0.0095 0.0122 0.0185
Trichomonas vaginalis cyclins, putative 0.024 0.0874 0.5483
Echinococcus granulosus calcium:calmodulin dependent protein kinase type 0.0106 0.0179 0.0229
Schistosoma mansoni tensin 0.0078 0.0036 0.0026
Echinococcus multilocularis proto oncogene serine:threonine protein kinase 0.0509 0.2267 0.3574
Loa Loa (eye worm) hypothetical protein 0.0078 0.0036 0.0016
Loa Loa (eye worm) nicotinic acetylcholine receptor alpha subunit 0.017 0.0509 0.049
Loa Loa (eye worm) LGC-31 protein 0.017 0.0509 0.049
Echinococcus multilocularis c Jun NH2 terminal kinase 0.0263 0.0993 0.1563
Schistosoma mansoni Cys-loop ligand gated ion channel subunit 0.017 0.0509 0.0774
Echinococcus granulosus epidermal growth factor receptor 0.0884 0.4213 0.5468
Echinococcus multilocularis Cys loop ligand gated ion channel subunit 0.0078 0.0035 0.005
Brugia malayi STE20-like kinase MST 0.0256 0.0956 0.0938
Schistosoma mansoni tyrosine kinase 0.0111 0.0206 0.0294
Trichomonas vaginalis CMGC family protein kinase 0.0141 0.0359 0.2084
Trypanosoma brucei cAMP-dependent protein kinase catalytic subunit 1 0.0158 0.0449 0.2111
Brugia malayi hypothetical protein 0.0107 0.0186 0.0167
Trichomonas vaginalis AGC family protein kinase 0.0095 0.0124 0.0533
Loa Loa (eye worm) hypothetical protein 0.0158 0.0449 0.043
Brugia malayi p70 ribosomal S6 kinase beta 0.0316 0.1266 0.1249
Trichomonas vaginalis CMGC family protein kinase 0.021 0.0717 0.4445
Echinococcus multilocularis neuronal acetylcholine receptor subunit alpha 4 0.017 0.0509 0.0798
Loa Loa (eye worm) hypothetical protein 0.017 0.0509 0.049
Plasmodium falciparum calcium-dependent protein kinase 5 0.0106 0.0179 0.1552
Toxoplasma gondii calcium-dependent protein kinase CDPK3 0.0106 0.0179 0.0833
Schistosoma mansoni tyrosine kinase 0.0402 0.1712 0.268
Giardia lamblia Kinase, CMGC GSK 0.0181 0.0568 0.3343
Entamoeba histolytica protein kinase domain containing protein 0.0181 0.0568 0.373
Entamoeba histolytica protein kinase domain containing protein 0.0106 0.0179 0.1178
Loa Loa (eye worm) hypothetical protein 0.0114 0.0222 0.0203
Echinococcus granulosus Serine:threonine protein kinase PLK4 0.0148 0.0398 0.0513
Loa Loa (eye worm) AGC/PKC/ETA protein kinase 0.0225 0.0795 0.0777
Brugia malayi tRNA modification GTPase TrmE family protein 0.0078 0.0036 0.0016
Brugia malayi Hr1 repeat family protein 0.0301 0.1188 0.1171
Schistosoma mansoni serine/threonine protein kinase 0.0188 0.0602 0.0922
Trichomonas vaginalis CAMK family protein kinase 0.0113 0.0218 0.115
Echinococcus granulosus tyrosine protein kinase Fyn 0.0278 0.1072 0.1387
Schistosoma mansoni tensin 0.0078 0.0036 0.0026
Giardia lamblia Kinase, NEK 0.014 0.0355 0.1852
Schistosoma mansoni protein kinase 0.0426 0.1838 0.2878
Leishmania major protein kinase, putative 0.0106 0.0179 0.0521
Echinococcus granulosus rho-associated protein kinase 1 0.0322 0.1296 0.1679
Loa Loa (eye worm) hypothetical protein 0.017 0.0509 0.049
Echinococcus granulosus tyrosine protein kinase HCK 0.015 0.0406 0.0523
Entamoeba histolytica protein kinase, putative 0.0097 0.0135 0.0884
Onchocerca volvulus 0.0181 0.0568 0.2204
Echinococcus granulosus tyrosine protein kinase transmembrane receptor 0.0089 0.0092 0.0115
Loa Loa (eye worm) STE/STE20/MSN protein kinase 0.0156 0.044 0.0421
Toxoplasma gondii calcium-dependent protein kinase CDPK2A 0.0106 0.0179 0.0833
Brugia malayi Phorbol esters/diacylglycerol binding domain 0.0224 0.0792 0.0774
Brugia malayi Neurotransmitter-gated ion-channel transmembrane region family protein 0.017 0.0509 0.049
Trichomonas vaginalis CAMK family protein kinase 0.0095 0.0122 0.0521
Echinococcus granulosus SHC transforming protein 3 0.0078 0.0036 0.0043
Entamoeba histolytica PH domain containing protein kinase, putative 0.0169 0.0504 0.3313
Trypanosoma cruzi aurora B kinase, putative 0.0208 0.0709 0.3945
Loa Loa (eye worm) hypothetical protein 0.0165 0.0485 0.0467
Entamoeba histolytica protein kinase, putative 0.0087 0.0079 0.0521
Echinococcus granulosus ribosomal protein S6 kinase alpha 3 0.0257 0.0961 0.1244
Echinococcus granulosus sodium:potassium dependent atpase beta subunit 0.014 0.0353 0.0454
Echinococcus granulosus RNA directed DNA polymerase 0.0078 0.0034 0.004
Echinococcus multilocularis 0.0078 0.0036 0.0052
Entamoeba histolytica protein kinase, putative 0.0109 0.0192 0.1262
Echinococcus multilocularis homeodomain interacting protein kinase 3 0.0204 0.0686 0.1078
Onchocerca volvulus 0.017 0.0509 0.1972
Onchocerca volvulus 0.0091 0.0103 0.0379
Echinococcus multilocularis cyclin dependent kinase 1 0.021 0.0717 0.1127
Loa Loa (eye worm) hypothetical protein 0.024 0.0874 0.0856
Leishmania major CYC2-like cyclin, putative,cyclin 6, putative 0.024 0.0874 0.4618
Onchocerca volvulus 0.017 0.0509 0.1972
Trypanosoma cruzi cdc2-related kinase 3 0.021 0.0717 0.399
Echinococcus multilocularis tensin 0.0078 0.0036 0.0052
Plasmodium vivax casein kinase 2, alpha subunit, putative 0.0105 0.0176 0.1972
Brugia malayi Protein kinase domain containing protein 0.0144 0.0374 0.0355
Trichomonas vaginalis CMGC family protein kinase 0.0143 0.0369 0.2151
Brugia malayi Protein kinase domain containing protein 0.0144 0.0374 0.0355
Echinococcus multilocularis tyrosine protein kinase transmembrane receptor 0.0089 0.0092 0.014
Plasmodium vivax unspecified product 0.0105 0.0176 0.1972
Loa Loa (eye worm) TK/FER protein kinase 0.0144 0.0374 0.0355
Brugia malayi putative serine/threonine kinase SADA gamma 0.0095 0.0122 0.0103
Loa Loa (eye worm) hypothetical protein 0.017 0.0509 0.049
Echinococcus granulosus serine:threonine protein kinase 0.008 0.0043 0.0052
Trypanosoma brucei protein kinase A catalytic subunit, putative 0.0158 0.0449 0.2111
Plasmodium falciparum cyclin 0.0146 0.0385 0.4789
Loa Loa (eye worm) CAMK/MLCK protein kinase 0.0093 0.0112 0.0092
Entamoeba histolytica cell division protein kinase 2, putative 0.0218 0.0758 0.4981
Trichomonas vaginalis AGC family protein kinase 0.0326 0.1321 0.8433
Schistosoma mansoni serine/threonine protein kinase 0.0109 0.0196 0.028
Echinococcus multilocularis serine:threonine protein kinase N2 0.0301 0.1188 0.1871
Loa Loa (eye worm) AGC/PKG protein kinase 0.0138 0.0347 0.0328
Schistosoma mansoni acetylcholine receptor-related 0.0078 0.0035 0.0024
Echinococcus granulosus tyrosine protein phosphatase non receptor type 0.0078 0.0036 0.0043
Brugia malayi hypothetical protein 0.0078 0.0035 0.0015
Echinococcus granulosus serine:threonine kinase SAD 1 0.0095 0.0122 0.0155
Trypanosoma cruzi glycogen synthase kinase 3, putative 0.0181 0.0568 0.3152
Echinococcus multilocularis nAChR subunit 0.017 0.0509 0.0798
Trichomonas vaginalis CAMK family protein kinase 0.0095 0.0122 0.0521
Brugia malayi glutamate-gated chloride channel alpha3A subunit, putative 0.0091 0.0103 0.0084
Entamoeba histolytica protein kinase, putative 0.0089 0.0091 0.0597
Echinococcus multilocularis mitogen activated protein kinase 11 0.0416 0.1787 0.2816
Echinococcus granulosus tyrosine protein kinase ABL1 0.0552 0.249 0.3229
Schistosoma mansoni tyrosine kinase 0.0819 0.3875 0.6104
Echinococcus granulosus Vam6:Vps39 protein 0.0107 0.0186 0.0237
Loa Loa (eye worm) hypothetical protein 0.0134 0.0323 0.0304
Echinococcus multilocularis serine:threonine protein kinase MARK2 0.0148 0.0398 0.0624
Trichomonas vaginalis CMGC family protein kinase 0.0105 0.0176 0.0873
Echinococcus multilocularis myosin iiia 0.0091 0.0099 0.0151
Schistosoma mansoni serine/threonine protein kinase 0.0209 0.0715 0.1101
Echinococcus granulosus nervana 2 0.014 0.0353 0.0454
Trichomonas vaginalis cyclins, putative 0.024 0.0874 0.5483
Schistosoma mansoni serine/threonine protein kinase 0.0158 0.0449 0.068
Loa Loa (eye worm) ligand-Gated ion Channel family member 0.017 0.0509 0.049
Echinococcus granulosus serine:threonine protein kinase PAK 4 0.0371 0.1552 0.2012
Loa Loa (eye worm) hypothetical protein 0.0078 0.0035 0.0015
Schistosoma mansoni serine/threonine protein kinase 0.0144 0.0374 0.0561
Leishmania major casein kinase, putative 0.0114 0.0218 0.075
Giardia lamblia Kinase, CMGC GSK 0.0181 0.0568 0.3343
Echinococcus granulosus tyrosine kinase 0.0228 0.0812 0.1051
Echinococcus granulosus CDC7 cell division cycle 7 0.0209 0.0715 0.0924
Trypanosoma cruzi mitogen activated protein kinase 4, putative 0.0141 0.0359 0.1981
Brugia malayi acetylcholine receptor, alpha-type subunit unc-38 precursor 0.017 0.0509 0.049
Entamoeba histolytica cyclin, putative 0.024 0.0874 0.5742
Loa Loa (eye worm) hypothetical protein 0.0078 0.0034 0.0014
Schistosoma mansoni signal transduction protein lnk-related 0.0078 0.0036 0.0026
Trypanosoma cruzi rac serine-threonine kinase, putative 0.018 0.0565 0.3135
Schistosoma mansoni serine/threonine protein kinase 0.0214 0.0739 0.1139
Loa Loa (eye worm) TK/FER protein kinase 0.0144 0.0374 0.0355
Brugia malayi Stress-activated protein kinase jnk-1 0.0263 0.0993 0.0975
Trypanosoma brucei cdc2-related kinase 3 0.021 0.0717 0.3691
Entamoeba histolytica serine/threonine protein kinase STE20, putative 0.0091 0.0099 0.0648
Echinococcus multilocularis cyclin dependent kinase 9 0.0094 0.0118 0.0181
Loa Loa (eye worm) calcium/calmodulin-dependent protein kinase subunit type II alpha 0.032 0.1288 0.1271
Loa Loa (eye worm) AGC/PKC/ALPHA protein kinase 0.0121 0.0259 0.0239
Echinococcus granulosus nicotinic acetylcholine receptor subunit type 0.017 0.0509 0.0656
Echinococcus granulosus Protein kinase C brain isozyme 0.0303 0.12 0.1554
Loa Loa (eye worm) CMGC/DYRK/DYRK2 protein kinase 0.0143 0.0369 0.035
Brugia malayi Acetylcholine receptor protein, alpha-like chain 1 precursor 0.0078 0.0035 0.0015
Trichomonas vaginalis AGC family protein kinase 0.0208 0.0709 0.4392
Echinococcus multilocularis serine threonine protein kinase 0.0144 0.0374 0.0585
Echinococcus granulosus nicotinic acetylcholine receptor subunit alpha 8 0.017 0.0509 0.0656
Entamoeba histolytica protein kinase, putative 0.0208 0.0709 0.4657
Schistosoma mansoni tyrosine kinase 0.0356 0.1472 0.23
Echinococcus multilocularis activin receptor type 0.0106 0.0179 0.0278
Echinococcus multilocularis CDC7 cell division cycle 7 0.0209 0.0715 0.1124
Loa Loa (eye worm) hypothetical protein 0.017 0.0509 0.049
Onchocerca volvulus 0.017 0.0509 0.1972
Schistosoma mansoni tyrosine kinase 0.0473 0.2083 0.3267
Echinococcus multilocularis cyclins 0.0146 0.0385 0.0603
Echinococcus multilocularis nicotinic acetylcholine receptor subunit type 0.0078 0.0035 0.005
Echinococcus multilocularis glycine receptor subunit beta 0.017 0.0509 0.0798
Echinococcus multilocularis serine:threonine kinase SAD 1 0.0095 0.0122 0.0188
Schistosoma mansoni cyclin B 0.024 0.0874 0.1353
Echinococcus granulosus casein kinase I alpha 0.0114 0.0218 0.0279
Echinococcus granulosus insulin growth factor 1 receptor beta 0.0902 0.4306 0.5589
Echinococcus granulosus cAMP dependent protein kinase catalytic subunit 0.0158 0.0449 0.0579
Echinococcus granulosus dual specificity 0.0143 0.0369 0.0475
Echinococcus multilocularis serine:threonine protein kinase N2 0.0125 0.0275 0.0429
Schistosoma mansoni hypothetical protein 0.0078 0.0036 0.0026
Echinococcus granulosus raf serine:threonine protein kinase 0.0112 0.0208 0.0265
Leishmania major cell division related protein kinase 2,cdc2-related kinase 0.021 0.0717 0.3691
Echinococcus multilocularis epidermal growth factor receptor 0.0884 0.4213 0.6647
Echinococcus multilocularis tyrosine protein kinase Src42A 0.0278 0.1072 0.1687
Trypanosoma cruzi casein kinase, putative 0.0114 0.0218 0.1189
Echinococcus multilocularis cyclin dependent kinase 0.021 0.0717 0.1127
Echinococcus multilocularis rac serine:threonine kinase 0.0191 0.062 0.0974
Plasmodium vivax protein kinase Crk2 0.021 0.0717 1
Loa Loa (eye worm) CAMK/CAMKL/MELK protein kinase 0.0188 0.0605 0.0587
Trichomonas vaginalis CAMK family protein kinase 0.0095 0.0122 0.0521
Schistosoma mansoni protein kinase 0.0156 0.044 0.0665
Loa Loa (eye worm) hypothetical protein 0.0095 0.0122 0.0103
Echinococcus multilocularis Cys loop ligand gated ion channel subunit 0.017 0.0509 0.0798
Giardia lamblia Kinase, CMGC CDK 0.021 0.0717 0.4389
Echinococcus granulosus tyrosine protein kinase Src42A 0.0165 0.0484 0.0624
Echinococcus multilocularis cyclin dependent kinase 9 0.0086 0.0077 0.0116
Brugia malayi Protein kinase domain containing protein 0.0586 0.2665 0.265
Echinococcus multilocularis nervana 2 0.014 0.0353 0.0552
Loa Loa (eye worm) SH2 domain-containing protein 0.0078 0.0036 0.0016
Schistosoma mansoni nephrin 0.0158 0.0447 0.0677
Trypanosoma cruzi dual specificity tyrosine-phosphorylation-regulated kinase 2, putative 0.0143 0.0369 0.2037
Plasmodium vivax serine/threonine protein kinase KIN, putative 0.0103 0.0164 0.1793
Echinococcus multilocularis dual specificity 0.0143 0.0369 0.0578
Loa Loa (eye worm) hypothetical protein 0.0078 0.0035 0.0015
Giardia lamblia Kinase, STE STE20 0.0091 0.0099 0.0054
Trichomonas vaginalis cyclin B, putative 0.0146 0.0385 0.2257
Trichomonas vaginalis STE family protein kinase 0.014 0.0355 0.2057
Onchocerca volvulus 0.0281 0.1084 0.4234
Onchocerca volvulus 0.0144 0.0374 0.1444
Echinococcus multilocularis c src tyrosine kinase 0.0194 0.0634 0.0995
Echinococcus multilocularis serine:threonine protein kinase 3 0.0256 0.0956 0.1504
Trichomonas vaginalis CAMK family protein kinase 0.0095 0.0122 0.0521
Loa Loa (eye worm) hypothetical protein 0.0123 0.0269 0.025
Loa Loa (eye worm) camk/dcamkl protein kinase 0.0154 0.0428 0.0409
Echinococcus granulosus serine threonine protein kinase 0.0144 0.0374 0.0481
Trypanosoma cruzi serine/arginine-rich protein specific kinase SRPK, putative 0.0089 0.0091 0.0474
Loa Loa (eye worm) CAMK/CAMKL/CHK1 protein kinase 0.0371 0.1553 0.1536
Echinococcus granulosus serine:threonine protein kinase PAK 3 0.0108 0.0187 0.0239
Echinococcus granulosus cGMP dependent protein kinase 1 0.0138 0.0347 0.0447
Loa Loa (eye worm) hypothetical protein 0.017 0.0509 0.049
Entamoeba histolytica protein kinase, putative 0.0097 0.0135 0.0884
Trichomonas vaginalis cyclin A, putative 0.024 0.0874 0.5483
Schistosoma mansoni protein kinase 0.0106 0.0179 0.0253
Echinococcus multilocularis tyrosine protein kinase ABL1 0.0552 0.249 0.3926
Plasmodium vivax NIMA-related protein kinase (Pfnek-1), putative 0.014 0.0355 0.4633
Brugia malayi protein-tyrosine kinase 0.0228 0.0812 0.0794
Brugia malayi Protein kinase domain containing protein 0.0194 0.0637 0.0619
Plasmodium falciparum protein kinase, putative 0.0106 0.0179 0.1552
Brugia malayi Serine/threonine-protein kinase Nek7 0.025 0.0923 0.0905
Schistosoma mansoni serine/threonine protein kinase 0.0176 0.0542 0.0828
Echinococcus multilocularis serine:threonine protein kinase TAO1 0.0413 0.1772 0.2792
Echinococcus granulosus cAMP dependent protein kinase catalytic subunit 0.0158 0.0449 0.0579
Trypanosoma brucei dual specificity tyrosine-phosphorylation-regulated kinase 2, putative 0.0143 0.0369 0.1641
Loa Loa (eye worm) AGC/PKN protein kinase 0.0301 0.1188 0.1171
Brugia malayi map kinase activated protein kinase protein 2 0.057 0.2583 0.2568
Loa Loa (eye worm) hypothetical protein 0.0137 0.0341 0.0322
Trypanosoma cruzi Vacuolar sorting protein 39 domain 1/Vacuolar sorting protein 39 domain 2, putative 0.0107 0.0186 0.1008
Loa Loa (eye worm) hypothetical protein 0.017 0.0509 0.049
Echinococcus multilocularis tyrosine protein kinase Fyn 0.0278 0.1072 0.1687
Schistosoma mansoni GTPase activating protein 0.0078 0.0036 0.0026
Brugia malayi Neurotransmitter-gated ion-channel ligand binding domain containing protein 0.017 0.0509 0.049
Trichomonas vaginalis CMGC family protein kinase 0.0105 0.0176 0.0873
Schistosoma mansoni serine/threonine kinase 0.0176 0.0542 0.0828
Entamoeba histolytica serine/threonine protein kinase, putative 0.0364 0.1517 0.9968
Loa Loa (eye worm) hypothetical protein 0.0133 0.0321 0.0302
Echinococcus granulosus casein kinase I alpha 0.0114 0.0218 0.0279
Plasmodium falciparum cAMP-dependent protein kinase catalytic subunit 0.0158 0.0449 0.579
Schistosoma mansoni glycogen synthase kinase 3-related (gsk3) (cmgc group III) 0.0181 0.0568 0.0868
Trypanosoma cruzi SNF1-related protein kinases, putative 0.0095 0.0122 0.0651
Schistosoma mansoni nAChR subunit 0.017 0.0509 0.0774
Toxoplasma gondii aurora kinase 0.0208 0.0709 0.5301
Schistosoma mansoni serine/threonine protein kinase 0.0095 0.0122 0.0163
Brugia malayi Cam kinase protein 1 0.0106 0.0179 0.016
Plasmodium falciparum calcium-dependent protein kinase 4 0.0106 0.0179 0.1552
Entamoeba histolytica cyclin family protein 0.0146 0.0385 0.2531
Echinococcus granulosus cyclin B3 1 0.0146 0.0385 0.0496
Echinococcus multilocularis tyrosine protein kinase Fyn 0.0278 0.1072 0.1687
Entamoeba histolytica SH2 domain containing protein 0.0078 0.0036 0.0237
Echinococcus granulosus serine:threonine protein kinase Chk2 0.0077 0.003 0.0035
Brugia malayi Cyclin, N-terminal domain containing protein 0.024 0.0874 0.0856
Loa Loa (eye worm) hypothetical protein 0.0078 0.0035 0.0015
Echinococcus multilocularis nicotinic acetylcholine receptor alpha subunit 0.017 0.0509 0.0798
Loa Loa (eye worm) hypothetical protein 0.0078 0.0036 0.0016
Brugia malayi casein kinase I 0.0114 0.0218 0.0199
Echinococcus granulosus nAChR subunit 0.0091 0.0103 0.013
Brugia malayi Fes/CIP4 homology domain containing protein 0.0123 0.0267 0.0248
Schistosoma mansoni serine/threonine protein kinase 0.0095 0.0122 0.0163
Entamoeba histolytica cell division protein kinase 2, putative 0.021 0.0717 0.471
Echinococcus multilocularis ribosomal protein s6 kinase beta 1 0.0176 0.0542 0.0851
Echinococcus multilocularis neuroglian 0.0147 0.0393 0.0616
Brugia malayi Protein kinase domain containing protein 0.0348 0.1432 0.1415
Loa Loa (eye worm) hypothetical protein 0.0091 0.0103 0.0084
Schistosoma mansoni pyruvate dehydrogenase 0.0121 0.0254 0.0371
Echinococcus multilocularis G2:mitotic specific cyclin B3 0.0258 0.0969 0.1525
Loa Loa (eye worm) hypothetical protein 0.017 0.0509 0.049
Echinococcus multilocularis protein tyrosine kinase 0.032 0.1289 0.203
Echinococcus granulosus twitchin 0.0188 0.0605 0.0781
Entamoeba histolytica cyclin, putative 0.0146 0.0385 0.2531
Schistosoma mansoni neurotransmitter gated ion channel 0.0078 0.0035 0.0024
Trypanosoma brucei cAMP-dependent protein kinase catalytic subunit 2 0.0158 0.0449 0.2111
Plasmodium falciparum calcium-dependent protein kinase 2 0.0106 0.0179 0.1552
Loa Loa (eye worm) hypothetical protein 0.1923 0.9595 0.9594
Loa Loa (eye worm) hypothetical protein 0.023 0.0823 0.0805
Schistosoma mansoni Cys-loop ligand gated ion channel subunit 0.017 0.0509 0.0774
Onchocerca volvulus 0.0091 0.0103 0.0379
Echinococcus multilocularis NCK adaptor protein 0.013 0.0305 0.0477
Echinococcus multilocularis casein kinase I alpha 0.0114 0.0218 0.0339
Brugia malayi RhoGAP domain containing protein 0.0125 0.0276 0.0257
Giardia lamblia Kinase, CMGC CDK 0.021 0.0717 0.4389
Echinococcus multilocularis serine:threonine protein kinase 38 0.0176 0.0542 0.0851
Schistosoma mansoni serine/threonine protein kinase 0.0095 0.0122 0.0163
Brugia malayi Variant SH3 domain containing protein 0.0128 0.0295 0.0276
Loa Loa (eye worm) hypothetical protein 0.0107 0.0186 0.0167
Trichomonas vaginalis CAMK family protein kinase 0.0364 0.1517 0.9727
Echinococcus granulosus cyclins 0.0146 0.0385 0.0496
Onchocerca volvulus 0.017 0.0509 0.1972
Echinococcus multilocularis cyclins 0.0146 0.0385 0.0603
Schistosoma mansoni tyrosine kinase 0.0884 0.4213 0.6639
Schistosoma mansoni serine/threonine protein kinase 0.0371 0.1553 0.2427
Brugia malayi Bromodomain containing protein 0.0091 0.0099 0.0079
Giardia lamblia Kinase, TTK 0.0113 0.0218 0.0888
Loa Loa (eye worm) RhoGAP domain-containing protein 0.0125 0.0276 0.0257
Trichomonas vaginalis cyclin B, putative 0.024 0.0874 0.5483
Echinococcus multilocularis serine:threonine protein kinase PAK 3 0.0108 0.0187 0.0291
Brugia malayi Protein kinase domain containing protein 0.0371 0.1553 0.1536
Trypanosoma brucei protein kinase, putative 0.0181 0.0568 0.2811
Echinococcus granulosus proto oncogene tyrosine protein kinase LCK 0.0278 0.1072 0.1387
Schistosoma mansoni serine/threonine protein kinase 0.0089 0.0091 0.0113
Entamoeba histolytica protein kinase, putative 0.0316 0.1266 0.8316
Entamoeba histolytica protein kinase domain containing protein 0.0086 0.0077 0.0504
Schistosoma mansoni serine/threonine protein kinase 0.0141 0.0359 0.0537
Echinococcus granulosus N chimaerin 0.0125 0.0276 0.0354
Giardia lamblia Kinase, CK1 Casein kinase 0.0114 0.0218 0.0892
Echinococcus multilocularis cyclin B 0.024 0.0874 0.1375
Echinococcus granulosus melanoma receptor tyrosine protein kinase 0.0884 0.4213 0.5468
Echinococcus granulosus cyclin B 0.024 0.0874 0.1131
Trichomonas vaginalis CAMK family protein kinase 0.0095 0.0122 0.0521
Echinococcus granulosus dual specificity serine:threonine tyrosine 0.0113 0.0218 0.0278
Trichomonas vaginalis CMGC family protein kinase 0.021 0.0717 0.4445
Echinococcus multilocularis acetylcholine receptor subunit beta 1 0.017 0.0509 0.0798
Trichomonas vaginalis CMGC family protein kinase 0.0141 0.0359 0.2084
Schistosoma mansoni serine/threonine protein kinase 0.0095 0.0122 0.0163
Giardia lamblia Kinase, CMGC CK2 0.0105 0.0176 0.0594
Echinococcus multilocularis cyclins 0.0146 0.0385 0.0603
Entamoeba histolytica SH2-protein kinase domain containing protein 0.0144 0.0374 0.2458
Brugia malayi Tyrosine-protein kinase abl-1 0.0252 0.0936 0.0918
Trichomonas vaginalis AGC family protein kinase 0.0087 0.0083 0.0261
Brugia malayi excitatory GABA receptor EXP-1A 0.017 0.0509 0.049
Loa Loa (eye worm) hypothetical protein 0.008 0.0043 0.0024
Echinococcus granulosus acetylcholine receptor subunit beta 1 0.017 0.0509 0.0656
Brugia malayi MAP kinase sur-1 0.0141 0.0359 0.034
Plasmodium falciparum casein kinase 1 0.0114 0.0218 0.2163
Echinococcus granulosus dual specificity 0.0143 0.0369 0.0475
Brugia malayi Protein kinase domain containing protein 0.0167 0.0494 0.0476
Brugia malayi Protein kinase domain containing protein 0.021 0.0717 0.0699
Echinococcus multilocularis protein kinase c epsilon type 0.0225 0.0795 0.1251
Loa Loa (eye worm) hypothetical protein 0.0083 0.006 0.004
Echinococcus granulosus casein kinase I delta 0.0114 0.0218 0.0279
Brugia malayi Tensin 0.0078 0.0036 0.0016
Plasmodium vivax cAMP-dependent protein kinase catalytic subunit, putative 0.0158 0.0449 0.6026
Schistosoma mansoni tyrosine kinase 0.032 0.1289 0.2009
Echinococcus granulosus serine:threonine protein kinase N2 0.0301 0.1188 0.1539
Toxoplasma gondii cell-cycle-associated protein kinase CDK, putative 0.021 0.0717 0.5369
Loa Loa (eye worm) hypothetical protein 0.0309 0.1233 0.1216
Loa Loa (eye worm) TK/FER protein kinase 0.0144 0.0374 0.0355
Schistosoma mansoni adapter molecule crk 0.0128 0.0295 0.0437
Leishmania major protein kinase, putative,polo-like protein kinase, putative 0.0364 0.1517 0.841
Echinococcus granulosus tyrosine protein kinase Blk 0.0228 0.0812 0.1051
Brugia malayi Doublecortin family protein 0.0154 0.0428 0.0409
Toxoplasma gondii protein kinase, cAMP-dependent, catalytic chain 0.0158 0.0449 0.3108
Brugia malayi hypothetical protein 0.0078 0.0035 0.0015
Schistosoma mansoni nAChR subunit 0.0078 0.0035 0.0024
Echinococcus granulosus basic fibroblast growth factor receptor 1 A 0.0356 0.1472 0.1908
Entamoeba histolytica serine/threonine- protein kinase 6 , putative 0.0208 0.0709 0.4657
Echinococcus granulosus STE20 serine:threonine protein kinase 0.0484 0.2139 0.2774
Echinococcus multilocularis cGMP dependent protein kinase 1 0.0138 0.0347 0.0543
Onchocerca volvulus Serine\/threonine kinase homolog 0.0364 0.1517 0.5934
Loa Loa (eye worm) TK/EGFR protein kinase 0.1294 0.6337 0.633
Loa Loa (eye worm) CMGC/MAPK/JNK protein kinase 0.0263 0.0993 0.0975
Trichomonas vaginalis CMGC family protein kinase 0.0143 0.0369 0.2151
Echinococcus multilocularis gamma aminobutyric acid receptor subunit 0.0078 0.0035 0.005
Loa Loa (eye worm) AGC/DMPK/GEK protein kinase 0.0347 0.1426 0.1409
Brugia malayi cell division control protein 2 homolog 0.021 0.0717 0.0699
Loa Loa (eye worm) AUR protein kinase 0.0208 0.0709 0.0691
Schistosoma mansoni cell adhesion molecule 0.0152 0.0415 0.0626
Trypanosoma brucei cdc2-related kinase 1 0.021 0.0717 0.3691
Brugia malayi cAMP-dependent protein kinase catalytic subunit, putative 0.0158 0.0449 0.043
Echinococcus granulosus epidermal growth factor receptor 0.1294 0.6337 0.8225
Brugia malayi Cyclin, N-terminal domain containing protein 0.0258 0.0969 0.0952
Loa Loa (eye worm) NEK/NEK6 protein kinase 0.025 0.0923 0.0905
Plasmodium vivax serine/threonine protein kinase 6, putative 0.0208 0.0709 0.9881
Toxoplasma gondii AGC kinase 0.0158 0.0449 0.3108
Plasmodium falciparum calcium-dependent protein kinase 3 0.0106 0.0179 0.1552
Schistosoma mansoni protein kinase 0.0106 0.0179 0.0253
Schistosoma mansoni vav2 0.0135 0.0331 0.0493
Loa Loa (eye worm) hypothetical protein 0.0144 0.0374 0.0355
Loa Loa (eye worm) AGC/RSK/RSK protein kinase 0.0257 0.0961 0.0943
Entamoeba histolytica protein kinase domain containing protein 0.0204 0.0686 0.4508
Echinococcus multilocularis protein kinase shaggy 0.0181 0.0568 0.0891
Entamoeba histolytica serine/threonine protein kinase 6, putative 0.0208 0.0709 0.4657
Loa Loa (eye worm) TK/ALK protein kinase 0.0531 0.238 0.2365
Brugia malayi ribosomal protein S6 kinase alpha 3 0.0122 0.026 0.0241
Schistosoma mansoni serine/threonine protein kinase 0.0109 0.0196 0.028
Brugia malayi Neurotransmitter-gated ion-channel ligand binding domain containing protein 0.0078 0.0035 0.0015
Plasmodium falciparum protein kinase, putative 0.0144 0.0374 0.4607
Brugia malayi hypothetical protein 0.0078 0.0035 0.0015
Trichomonas vaginalis CAMK family protein kinase 0.0364 0.1517 0.9727
Brugia malayi Cyclin, N-terminal domain containing protein 0.0279 0.1077 0.1059
Loa Loa (eye worm) hypothetical protein 0.0123 0.0269 0.025
Trypanosoma cruzi STE/STE20 serine/threonine-protein kinase, putative 0.0091 0.0099 0.0518
Onchocerca volvulus 0.0107 0.0186 0.0705
Brugia malayi Variant SH3 domain containing protein 0.0128 0.0295 0.0276
Echinococcus granulosus maternal embryonic leucine zipper kinase 0.012 0.025 0.0321
Echinococcus granulosus tyrosine kinase 0.0144 0.0374 0.0482
Brugia malayi Homeodomain interacting protein kinase protein 1 0.0204 0.0686 0.0668
Loa Loa (eye worm) cyclin domain-containing protein 0.0279 0.1077 0.1059
Giardia lamblia Kinase, PLK 0.0364 0.1517 1
Plasmodium vivax casein kinase 1, putative 0.0114 0.0218 0.2603
Trypanosoma cruzi casein kinase II, putative 0.0105 0.0176 0.095
Loa Loa (eye worm) AUR protein kinase 0.0208 0.0709 0.0691
Brugia malayi Immunoglobulin I-set domain containing protein 0.0681 0.316 0.3146
Echinococcus granulosus Pyruvate dehydrogenase lipoamide kinase 0.0121 0.0254 0.0326
Trypanosoma cruzi casein kinase, putative 0.0114 0.0218 0.1189
Echinococcus multilocularis serine:threonine protein kinase MARK2 0.0148 0.0398 0.0624
Onchocerca volvulus 0.0114 0.0218 0.0832
Trichomonas vaginalis STE family protein kinase 0.0087 0.0079 0.0238
Echinococcus granulosus expressed conserved protein 0.0078 0.0036 0.0043
Trichomonas vaginalis AGC family protein kinase 0.0187 0.0598 0.3659
Echinococcus multilocularis GTPase activating Rap:RanGAP domain 3 0.0107 0.0186 0.0289
Loa Loa (eye worm) hypothetical protein 0.0091 0.0103 0.0084
Loa Loa (eye worm) hypothetical protein 0.0078 0.0036 0.0016
Brugia malayi Protein kinase domain containing protein 0.0144 0.0374 0.0355
Echinococcus granulosus defective proboscis extension response 0.0123 0.0269 0.0345
Loa Loa (eye worm) CAMK/PIM protein kinase 0.0509 0.2267 0.2252
Loa Loa (eye worm) TK protein kinase 0.0228 0.0812 0.0794
Schistosoma mansoni protein kinase 0.0114 0.0218 0.0314
Trypanosoma cruzi STE/STE11 serine/threonine-protein kinase, putative 0.0106 0.0179 0.0971
Brugia malayi hypothetical protein 0.0144 0.0374 0.0355
Onchocerca volvulus 0.0078 0.0036 0.0116
Echinococcus granulosus tyrosine protein kinase 0.0296 0.1161 0.1504
Echinococcus multilocularis proto oncogene tyrosine protein kinase LCK 0.0278 0.1072 0.1687
Trypanosoma cruzi polo-like protein kinase, putative 0.0364 0.1517 0.8486
Loa Loa (eye worm) variant SH3 domain-containing protein 0.0092 0.0104 0.0085
Brugia malayi acetylcholine receptor protein, alpha-like chain, putative 0.017 0.0509 0.049
Loa Loa (eye worm) hypothetical protein 0.0106 0.0179 0.016
Loa Loa (eye worm) CMGC/CDK/CDC2 protein kinase 0.021 0.0717 0.0699
Entamoeba histolytica protein kinase domain containing protein 0.0208 0.0709 0.4657
Loa Loa (eye worm) calcium/calmodulin-dependent protein kinase ID 0.0106 0.0179 0.016
Schistosoma mansoni SH2A 0.0078 0.0036 0.0026
Brugia malayi serine/threonine kinase 12 0.0208 0.0709 0.0691
Entamoeba histolytica PH domain containing protein kinase, putative 0.0191 0.062 0.4073
Loa Loa (eye worm) hypothetical protein 0.0078 0.0035 0.0015
Onchocerca volvulus 0.0078 0.0035 0.0112
Brugia malayi Neurotransmitter-gated ion-channel transmembrane region family protein 0.0091 0.0103 0.0084
Echinococcus multilocularis glycine receptor subunit alpha 1 0.017 0.0509 0.0798
Schistosoma mansoni tyrosine kinase 0.1294 0.6337 1
Loa Loa (eye worm) ACC-1 protein 0.017 0.0509 0.049
Trichomonas vaginalis STE family protein kinase 0.0144 0.0374 0.2181
Echinococcus multilocularis cyclins 0.0146 0.0385 0.0603
Schistosoma mansoni chimerin-related rho-gtpase-activating protein 0.0125 0.0276 0.0406
Brugia malayi glutamate-gated chloride channel alpha3A subunit, putative 0.0078 0.0035 0.0015
Echinococcus multilocularis Protein kinase C, brain isozyme 0.0303 0.12 0.1889
Trypanosoma brucei polo-like protein kinase 0.0364 0.1517 0.841
Echinococcus multilocularis Serine:threonine protein kinase PLK4 0.0148 0.0398 0.0624
Loa Loa (eye worm) CAMK/TSSK protein kinase 0.0586 0.2665 0.265
Giardia lamblia G2/mitotic-specific cyclin B 0.024 0.0874 0.5491
Trichomonas vaginalis CMGC family protein kinase 0.0181 0.0568 0.3461
Schistosoma mansoni tyrosine kinase 0.0884 0.4213 0.6639
Echinococcus multilocularis basement membrane specific heparan sulfate 0.0123 0.0269 0.0419
Schistosoma mansoni neurotransmitter gated ion channel 0.0091 0.0103 0.0132
Brugia malayi SH2 domain containing protein 0.0078 0.0036 0.0016
Brugia malayi Protein kinase domain containing protein 0.0087 0.0083 0.0063
Brugia malayi STAT protein, DNA binding domain containing protein 0.0078 0.0036 0.0016
Schistosoma mansoni tyrosine kinase 0.0278 0.1072 0.1665
Trichomonas vaginalis conserved hypothetical protein 0.0146 0.0385 0.2257
Echinococcus granulosus casein kinase I delta 0.0114 0.0218 0.0279
Trichomonas vaginalis AGC family protein kinase 0.0158 0.0449 0.2677
Leishmania major mitogen-activated protein kinase 3, putative,map kinase 3, putative 0.0416 0.1787 1
Trypanosoma cruzi casein kinase, delta isoform, putative 0.0114 0.0218 0.1189
Echinococcus multilocularis sodium:potassium dependent atpase beta subunit 0.014 0.0353 0.0552
Onchocerca volvulus 0.0322 0.1296 0.5065
Echinococcus multilocularis SH2 motif 0.0078 0.0036 0.0052
Trichomonas vaginalis CAMK family protein kinase 0.0095 0.0122 0.0521
Loa Loa (eye worm) hypothetical protein 0.0184 0.0581 0.0562
Loa Loa (eye worm) TK/ROR protein kinase 0.0089 0.0092 0.0072
Loa Loa (eye worm) hypothetical protein 0.0223 0.0784 0.0766
Echinococcus granulosus mitogen activated protein kinase 3 0.0141 0.0359 0.0462
Echinococcus granulosus protein kinase c iota type 0.0302 0.1195 0.1548
Loa Loa (eye worm) IKK protein kinase 0.0507 0.2256 0.2241
Trypanosoma cruzi mitogen-activated protein kinase 3, putative 0.0416 0.1787 1
Giardia lamblia Cyclin A 0.0146 0.0385 0.2064
Brugia malayi Protein kinase domain containing protein 0.0214 0.0739 0.0721
Loa Loa (eye worm) TK protein kinase 0.015 0.0406 0.0387
Plasmodium falciparum protein kinase 5 0.021 0.0717 1
Schistosoma mansoni chimerin-related rho-gtpase-activating protein 0.0125 0.0276 0.0406
Loa Loa (eye worm) glutamate-gated chloride channel alpha3A subunit 0.017 0.0509 0.049
Echinococcus granulosus 5' AMP activated protein kinase catalytic 0.0188 0.0602 0.0778
Loa Loa (eye worm) casein kinase 0.0173 0.0527 0.0509
Trichomonas vaginalis AGC family protein kinase 0.0184 0.0584 0.3566
Trichomonas vaginalis CMGC family protein kinase 0.0143 0.0369 0.2151
Schistosoma mansoni tensin-related 0.0078 0.0036 0.0026
Echinococcus multilocularis cyclin dependent kinase 5 0.021 0.0717 0.1127
Loa Loa (eye worm) hypothetical protein 0.0083 0.006 0.004
Schistosoma mansoni serine/threonine protein kinase 0.0112 0.0208 0.0298
Schistosoma mansoni mitogen-activated protein kinase kinase kinase 3 mapkkk3 mekk3 0.0107 0.0186 0.0263
Loa Loa (eye worm) hypothetical protein 0.0133 0.0321 0.0302
Entamoeba histolytica hypothetical protein 0.0365 0.1522 1
Trypanosoma brucei mitogen activated protein kinase 4, putative 0.0141 0.0359 0.1582
Loa Loa (eye worm) hypothetical protein 0.0091 0.0103 0.0084
Loa Loa (eye worm) hypothetical protein 0.024 0.0874 0.0856
Brugia malayi Calcium/calmodulin-dependent protein kinase type II alpha chain 0.0106 0.0179 0.016
Echinococcus granulosus serine:threonine protein kinase MARK2 0.0148 0.0398 0.0513
Leishmania major mitogen activated protein kinase 4, putative;with=GeneDB:LmxM19.1440 0.0141 0.0359 0.1582
Loa Loa (eye worm) AGC/RSK/MSK protein kinase 0.0176 0.0542 0.0524
Schistosoma mansoni serine/threonine protein kinase 0.0301 0.1188 0.185
Trichomonas vaginalis CAMK family protein kinase 0.0095 0.0122 0.0521
Echinococcus granulosus casein kinase ii subunit alpha 0.0105 0.0176 0.0224
Trypanosoma brucei rac serine-threonine kinase, putative 0.0326 0.1321 0.7254
Echinococcus multilocularis casein kinase I delta 0.0114 0.0218 0.0339
Loa Loa (eye worm) hypothetical protein 0.0085 0.0072 0.0053
Schistosoma mansoni kinase 0.0086 0.0077 0.009
Schistosoma mansoni tyrosine kinase 0.0819 0.3875 0.6104
Entamoeba histolytica serine/threonine-protein kinase 3, putative 0.0091 0.0099 0.0648
Plasmodium vivax calcium-dependent protein kinase 1, putative 0.0106 0.0179 0.2026
Onchocerca volvulus 0.0078 0.0036 0.0116
Loa Loa (eye worm) hypothetical protein 0.0526 0.2357 0.2342
Trypanosoma brucei Casein kinase II 0.0105 0.0176 0.0499
Loa Loa (eye worm) hypothetical protein 0.0078 0.0035 0.0015
Plasmodium vivax calcium-dependent protein kinase 4, putative 0.0106 0.0179 0.2026
Onchocerca volvulus 0.017 0.0509 0.1972
Leishmania major protein kinase, putative 0.0208 0.0709 0.3644
Loa Loa (eye worm) hypothetical protein 0.0078 0.0035 0.0015
Brugia malayi intracellular kinase 0.0181 0.0568 0.0549
Brugia malayi Protein kinase domain containing protein 0.0326 0.1321 0.1304
Echinococcus multilocularis serine:threonine protein kinase MRCK beta 0.0241 0.0879 0.1383
Trichomonas vaginalis CMGC family protein kinase 0.0209 0.0715 0.4432
Leishmania major mitogen activated protein kinase, putative,map kinase, putative 0.0141 0.0359 0.1582
Onchocerca volvulus 0.0209 0.0715 0.2782
Trypanosoma brucei protein kinase, putative 0.0149 0.04 0.1825
Brugia malayi Furin-like cysteine rich region family protein 0.1294 0.6337 0.633
Echinococcus multilocularis cAMP dependent protein kinase catalytic subunit 0.0158 0.0449 0.0704
Trichomonas vaginalis CMGC family protein kinase 0.0105 0.0176 0.0873
Brugia malayi Neurotransmitter-gated ion-channel ligand binding domain containing protein 0.0078 0.0035 0.0015
Toxoplasma gondii CMGC kinase, MAPK family (ERK) MAPK-1 0.0141 0.0359 0.2351
Schistosoma mansoni suppressor of cytokine signaling 0.0078 0.0036 0.0026
Brugia malayi SH2 domain containing protein 0.0078 0.0036 0.0016
Echinococcus multilocularis casein kinase I gamma 0.0214 0.0739 0.1162
Echinococcus granulosus nicotinic acetylcholine receptor alpha subunit 0.017 0.0509 0.0656
Echinococcus multilocularis dual specificity 0.0143 0.0369 0.0578
Schistosoma mansoni protein tyrosine phosphatase n11 (shp2) 0.0078 0.0036 0.0026
Trichomonas vaginalis CAMK family protein kinase 0.0095 0.0122 0.0521
Loa Loa (eye worm) hypothetical protein 0.0078 0.0035 0.0015
Loa Loa (eye worm) hypothetical protein 0.0124 0.0274 0.0255
Plasmodium falciparum serine/threonine protein kinase, putative 0.0208 0.0709 0.9874
Echinococcus multilocularis 3 phosphoinositide dependent protein kinase 1 0.0087 0.0083 0.0126
Trypanosoma cruzi casein kinase, putative 0.0114 0.0218 0.1189
Trichomonas vaginalis CMGC family protein kinase 0.0105 0.0176 0.0873
Echinococcus multilocularis tyrosine protein phosphatase non receptor type 0.0078 0.0036 0.0052
Echinococcus granulosus enhancer of mRNA decapping protein 4 0.0117 0.0237 0.0304
Giardia lamblia Kinase, AGC PKA 0.0158 0.0449 0.251
Brugia malayi SH2 domain containing protein 0.0078 0.0036 0.0016
Echinococcus granulosus protein kinase c epsilon type 0.0225 0.0795 0.1029
Schistosoma mansoni serine/threonine protein kinase 0.0138 0.0347 0.0519
Plasmodium falciparum casein kinase 2, alpha subunit 0.0105 0.0176 0.1495
Entamoeba histolytica cyclin family protein 0.0146 0.0385 0.2531
Echinococcus granulosus mitogen activated protein kinase kinase kinase 0.0148 0.0398 0.0512
Schistosoma mansoni serine/threonine protein kinase 0.0225 0.0795 0.1228
Echinococcus multilocularis ephrin type A receptor 4 A 0.0127 0.0286 0.0447
Loa Loa (eye worm) ACC-1 protein 0.017 0.0509 0.049
Trichomonas vaginalis cyclins, putative 0.024 0.0874 0.5483
Brugia malayi Protein kinase domain containing protein 0.0176 0.0542 0.0524
Onchocerca volvulus 0.0078 0.0035 0.0112
Echinococcus granulosus tyrosine protein kinase Fps85D 0.0435 0.1885 0.2444
Echinococcus multilocularis dual specificity serine:threonine tyrosine 0.0113 0.0218 0.0338
Echinococcus multilocularis cyclins 0.0146 0.0385 0.0603
Plasmodium falciparum calcium-dependent protein kinase 1 0.0106 0.0179 0.1552
Schistosoma mansoni tensin 0.0078 0.0036 0.0026
Loa Loa (eye worm) CAMK/CAMKL/MARK protein kinase 0.008 0.0043 0.0024
Echinococcus granulosus SH2 domain containing protein 7 0.0078 0.0036 0.0043
Plasmodium vivax serine/threonine-specific protein kinase, putative 0.0144 0.0374 0.491
Loa Loa (eye worm) hypothetical protein 0.0107 0.0186 0.0167
Loa Loa (eye worm) hypothetical protein 0.017 0.0509 0.049
Schistosoma mansoni serine/threonine protein kinase 0.057 0.2583 0.4058
Brugia malayi Protein-tyrosine phosphatase containing protein 0.0078 0.0036 0.0016
Trichomonas vaginalis CMGC family protein kinase 0.0143 0.0369 0.2151
Trichomonas vaginalis CAMK family protein kinase 0.0095 0.0122 0.0521
Onchocerca volvulus 0.0078 0.0035 0.0112
Schistosoma mansoni protein kinase 0.0426 0.1838 0.2878
Schistosoma mansoni serine/threonine protein kinase 0.0257 0.0961 0.1491
Trichomonas vaginalis CMGC family protein kinase 0.0209 0.0715 0.4432
Brugia malayi EST embl|AI107989|AI107989 comes from the 3' UTR, putative 0.0188 0.0602 0.0584
Loa Loa (eye worm) PEK/PEK protein kinase 0.0231 0.0829 0.0811
Brugia malayi serine/threonine-protein kinase plk-2 0.0364 0.1517 0.1501
Echinococcus multilocularis nicotinic acetylcholine receptor a11 subunit 0.017 0.0509 0.0798
Entamoeba histolytica SH2-protein kinase domain containing protein 0.0119 0.0248 0.1628
Brugia malayi hypothetical protein 0.0134 0.0323 0.0304
Brugia malayi Neurotransmitter-gated ion-channel ligand binding domain containing protein 0.017 0.0509 0.049
Schistosoma mansoni serine/threonine protein kinase 0.0509 0.2267 0.3558
Onchocerca volvulus Putative nachr subunit 0.017 0.0509 0.1972
Echinococcus multilocularis cyclins 0.0146 0.0385 0.0603
Echinococcus multilocularis serine threonine protein kinase nrc serine threonine protein kinase gad 0.018 0.0565 0.0886
Schistosoma mansoni serine/threonine protein kinase 0.0467 0.2052 0.3218
Loa Loa (eye worm) hypothetical protein 0.037 0.1547 0.153
Echinococcus granulosus MAP kinase activated protein kinase 2 0.057 0.2583 0.335
Toxoplasma gondii CMGC kinase, CK2 family 0.0105 0.0176 0.0802
Loa Loa (eye worm) hypothetical protein 0.0091 0.0103 0.0084
Echinococcus granulosus nicotinic acetylcholine receptor a11 subunit 0.017 0.0509 0.0656
Trichomonas vaginalis CAMK family protein kinase 0.012 0.025 0.1365
Brugia malayi nicotinic acetylcholine receptor beta-1 chain precursor 0.017 0.0509 0.049
Echinococcus granulosus tyrosine protein phosphatase non receptor type 0.0078 0.0036 0.0043
Echinococcus multilocularis phosphorylase kinase gamma subunit 0.0167 0.0494 0.0775
Entamoeba histolytica protein kinase 2, putative 0.018 0.0565 0.371
Echinococcus granulosus activin receptor type 0.0106 0.0179 0.0229
Loa Loa (eye worm) CDC7 protein kinase 0.0209 0.0715 0.0697
Trichomonas vaginalis cyclins, putative 0.0134 0.0326 0.1867
Schistosoma mansoni ephrin receptor 0.0076 0.0022 0.0003
Brugia malayi Calcium/calmodulin-dependent protein kinase type II alpha chain 0.032 0.1288 0.1271
Echinococcus multilocularis serine:threonine protein kinase PAK 3 0.0108 0.0187 0.0291
Loa Loa (eye worm) TK/FER protein kinase 0.0144 0.0374 0.0355
Loa Loa (eye worm) neuronal acetylcholine receptor protein 0.0078 0.0035 0.0015
Echinococcus multilocularis cGMP dependent protein kinase 1 0.0138 0.0347 0.0543
Schistosoma mansoni pyruvate dehydrogenase 0.0114 0.0219 0.0316
Loa Loa (eye worm) hypothetical protein 0.0091 0.0103 0.0084
Onchocerca volvulus 0.0133 0.0321 0.1234
Trichomonas vaginalis CMGC family protein kinase 0.0181 0.0568 0.3461
Trichomonas vaginalis cyclin B, putative 0.024 0.0874 0.5483
Echinococcus granulosus calcium:calmodulin dependent protein kinase type 1 0.0106 0.0179 0.0229
Echinococcus multilocularis glycine receptor subunit alpha 1 0.017 0.0509 0.0798
Trichomonas vaginalis CMGC family protein kinase 0.0143 0.0369 0.2151
Trichomonas vaginalis CAMK family protein kinase 0.0364 0.1517 0.9727
Brugia malayi Protein kinase domain containing protein 0.0089 0.0091 0.0071
Echinococcus granulosus Glutaredoxin protein 5 0.014 0.0353 0.0454
Schistosoma mansoni serine/threonine protein kinase 0.0322 0.1296 0.2021
Trichomonas vaginalis cyclin B, putative 0.024 0.0874 0.5483
Plasmodium vivax tyrosine kinase-like protein, putative 0.0087 0.0081 0.0561
Loa Loa (eye worm) hypothetical protein 0.0078 0.0036 0.0016
Echinococcus granulosus hypothetical protein 0.0078 0.0036 0.0043
Brugia malayi Protein kinase domain containing protein 0.0176 0.0542 0.0524
Loa Loa (eye worm) CAMK/PHK protein kinase 0.0167 0.0494 0.0476
Schistosoma mansoni serine/threonine protein kinase 0.0087 0.0083 0.01
Echinococcus granulosus cyclin dependent kinase 9 0.0086 0.0077 0.0096
Toxoplasma gondii AGC kinase 0.0158 0.0449 0.3108
Echinococcus granulosus serine:threonine protein kinase 0.008 0.0043 0.0052
Loa Loa (eye worm) AGC/PKA protein kinase 0.0158 0.0449 0.043
Loa Loa (eye worm) CAMK/CAMKL/AMPK protein kinase 0.0188 0.0602 0.0584
Loa Loa (eye worm) hypothetical protein 0.017 0.0509 0.049
Echinococcus granulosus neuronal acetylcholine receptor subunit alpha 4 0.017 0.0509 0.0656
Brugia malayi Variant SH3 domain containing protein 0.0092 0.0104 0.0085
Trypanosoma cruzi casein kinase, putative 0.0114 0.0218 0.1189
Trichomonas vaginalis AGC family protein kinase 0.0208 0.0709 0.4392
Trichomonas vaginalis CAMK family protein kinase 0.0095 0.0122 0.0521
Entamoeba histolytica casein kinase 1, putative 0.0114 0.0218 0.1433
Onchocerca volvulus Suppressor of cytokine signaling 7 homolog 0.0078 0.0036 0.0116
Loa Loa (eye worm) hypothetical protein 0.0078 0.0035 0.0015
Loa Loa (eye worm) CAMK/PKD protein kinase 0.0178 0.0552 0.0534
Loa Loa (eye worm) TK protein kinase 0.0296 0.1161 0.1144
Echinococcus multilocularis tyrosine protein kinase Abl 0.035 0.1442 0.2272
Brugia malayi Neurotransmitter-gated ion-channel transmembrane region family protein 0.0091 0.0103 0.0084
Brugia malayi Hypothetical glycine receptor like protein T20B12.9 in chromosome III 0.0091 0.0103 0.0084
Toxoplasma gondii cell-cycle-associated protein kinase SRPK, putative 0.0089 0.0091 0.0088
Echinococcus multilocularis dual specificity testis specific protein kinase 0.0106 0.0179 0.0278
Brugia malayi probable protein kinase 0.0264 0.0996 0.0978
Trichomonas vaginalis cyclin B3, putative 0.0146 0.0385 0.2257
Trichomonas vaginalis CMGC family protein kinase 0.0141 0.0359 0.2084
Loa Loa (eye worm) TK/FER protein kinase 0.0144 0.0374 0.0355
Echinococcus multilocularis serine:threonine protein kinase NIM1 0.0124 0.0272 0.0424
Loa Loa (eye worm) CMGC/GSK protein kinase 0.0181 0.0568 0.0549
Entamoeba histolytica protein kinase, putative 0.0144 0.0374 0.2455
Toxoplasma gondii histone kinase SNF1, putative 0.0095 0.0122 0.0352
Echinococcus multilocularis aurora kinase A 0.0208 0.0709 0.1114
Brugia malayi SH2 domain containing protein 0.0435 0.1885 0.1869
Schistosoma mansoni ephrin receptor 0.0127 0.0286 0.0422
Schistosoma mansoni neurotransmitter gated ion channel 0.0078 0.0035 0.0024
Brugia malayi Protein kinase domain containing protein 0.0531 0.2381 0.2366
Echinococcus granulosus Cys loop ligand gated ion channel subunit 0.0078 0.0035 0.0041
Trichomonas vaginalis CAMK family protein kinase 0.0095 0.0122 0.0521
Echinococcus multilocularis expressed conserved protein 0.0138 0.0347 0.0543
Echinococcus multilocularis tyrosine protein phosphatase non receptor type 0.0078 0.0036 0.0052
Echinococcus granulosus mitogen activated protein kinase 14 0.0416 0.1787 0.2316
Echinococcus multilocularis insulin growth factor 1 receptor beta 0.0902 0.4306 0.6794
Echinococcus granulosus tyrosine protein kinase Fyn 0.0278 0.1072 0.1387
Leishmania major cyclin 0.024 0.0874 0.4618
Onchocerca volvulus 0.0184 0.0581 0.2256
Loa Loa (eye worm) hypothetical protein 0.041 0.1753 0.1737
Trypanosoma cruzi STE/STE20 serine/threonine-protein kinase, putative 0.0091 0.0099 0.0518
Brugia malayi Neurotransmitter-gated ion-channel ligand binding domain containing protein 0.017 0.0509 0.049
Echinococcus multilocularis casein kinase ii subunit alpha 0.0105 0.0176 0.0272
Echinococcus multilocularis guanine nucleotide exchange factor VAV2 0.0125 0.0276 0.0431
Giardia lamblia Kinase, NEK 0.014 0.0355 0.1852
Schistosoma mansoni nAChR subunit 0.017 0.0509 0.0774
Entamoeba histolytica serine/threonine- protein kinase 6, putative 0.0208 0.0709 0.4657
Trichomonas vaginalis CAMK family protein kinase 0.0364 0.1517 0.9727
Echinococcus granulosus neurotracting:lsamp:neurotrimin:obcam 0.0141 0.0361 0.0465
Onchocerca volvulus 0.0078 0.0036 0.0116
Echinococcus granulosus insulin receptor 0.0892 0.4252 0.5518
Echinococcus granulosus suppressor of cytokine signaling 6 0.0078 0.0036 0.0043
Echinococcus multilocularis telomerase reverse transcriptase subunit 0.0078 0.0034 0.0049
Schistosoma mansoni serine/threonine protein kinase 0.0413 0.1772 0.2773
Trypanosoma brucei STE20-like serine/threonine-protein kinase 1, putative 0.0091 0.0099 0.0046
Schistosoma mansoni protein kinase C mu 0.0224 0.0792 0.1223
Schistosoma mansoni defective proboscis extension response (dpr)-related 0.0123 0.0269 0.0394
Loa Loa (eye worm) hypothetical protein 0.0124 0.0271 0.0252
Echinococcus granulosus serine:threonine protein kinase NIM1 0.0124 0.0272 0.0349
Echinococcus granulosus aurora kinase A 0.0208 0.0709 0.0916
Echinococcus granulosus glycine receptor subunit alpha 1 0.017 0.0509 0.0656
Echinococcus granulosus protein kinase C gamma type 0.0257 0.096 0.1242
Loa Loa (eye worm) AGC/DMPK/ROCK protein kinase 0.0914 0.4368 0.4357
Brugia malayi acetylcholine receptor alpha subunit precursor, putative 0.017 0.0509 0.049
Giardia lamblia Kinase, CMGC DYRK 0.0143 0.0369 0.1951
Trypanosoma cruzi cAMP-dependent protein kinase catalytic subunit 1 0.0158 0.0449 0.2485
Trichomonas vaginalis CAMK family protein kinase 0.0095 0.0122 0.0521
Schistosoma mansoni kinase 0.0335 0.1365 0.213
Onchocerca volvulus Serine\/threonine protein kinase homolog 0.0509 0.2267 0.8879
Echinococcus granulosus titin 0.0075 0.002 0.0021
Echinococcus granulosus glycine receptor subunit beta 0.017 0.0509 0.0656
Echinococcus granulosus dual specificity 0.0143 0.0369 0.0475
Schistosoma mansoni nAChR subunit (ShAR1-alpha-like) 0.017 0.0509 0.0774
Echinococcus multilocularis mitogen activated protein kinase kinase kinase 0.0148 0.0398 0.0623
Schistosoma mansoni protein kinase 0.0108 0.0187 0.0265
Echinococcus multilocularis mitogen activated protein kinase 11 0.0416 0.1787 0.2816
Echinococcus granulosus tyrosine protein kinase Fyn 0.0278 0.1072 0.1387
Echinococcus multilocularis nAChR subunit 0.0091 0.0103 0.0158
Trypanosoma cruzi cdc2-related kinase 3 0.021 0.0717 0.399
Echinococcus multilocularis glycine receptor subunit beta 0.017 0.0509 0.0798
Echinococcus granulosus proto oncogene serine:threonine protein kinase 0.0509 0.2267 0.294
Brugia malayi Protein kinase domain containing protein 0.008 0.0043 0.0024
Schistosoma mansoni pyruvate dehydrogenase 0.0114 0.0219 0.0316
Loa Loa (eye worm) hypothetical protein 0.018 0.0561 0.0542
Echinococcus granulosus fibroblast growth factor receptor 4 0.0356 0.1472 0.1908
Schistosoma mansoni serine/threonine protein kinase 0.0143 0.0369 0.0553
Echinococcus granulosus c-Jun N-terminal kinases 0.0263 0.0993 0.1286
Loa Loa (eye worm) hypothetical protein 0.0078 0.0036 0.0016
Echinococcus multilocularis mitogen activated protein kinase 3 0.0141 0.0359 0.0562
Loa Loa (eye worm) TK/INSR protein kinase 0.0892 0.4252 0.4241
Schistosoma mansoni dual specificity serine/threonine tyrosine kinase 0.0113 0.0218 0.0313
Loa Loa (eye worm) camk/mapkapk/mnk protein kinase 0.044 0.1911 0.1895
Loa Loa (eye worm) acetylcholine receptor alpha subunit 0.017 0.0509 0.049
Loa Loa (eye worm) hypothetical protein 0.0078 0.0036 0.0016
Onchocerca volvulus 0.0144 0.0374 0.1444

Activities

Activity type Activity value Assay description Source Reference
Potency (functional) = 0.1413 um PUBCHEM_BIOASSAY: qHTS Assay for Enhancers of SMN2 Splice Variant Expression. (Class of assay: confirmatory) ChEMBL. No reference
Potency (functional) 1.122 uM PUBCHEM_BIOASSAY: qHTS Assay for Inhibitors of BAZ2B. (Class of assay: confirmatory) [Related pubchem assays (depositor defined):AID504391] ChEMBL. No reference
Potency (functional) 5.8048 uM PUBCHEM_BIOASSAY: Nrf2 qHTS screen for inhibitors. (Class of assay: confirmatory) [Related pubchem assays (depositor defined):AID493153, AID493163, AID504648] ChEMBL. No reference
Potency (functional) 37.933 uM PUBCHEM_BIOASSAY: qHTS profiling assay for firefly luciferase inhibitor/activator using purified enzyme and Km concentrations of substrates (counterscreen for miR-21 project). (Class of assay: confirmatory) [Related pubchem assays (depositor defined):AID2288, AID2289, AID2598, AID411] ChEMBL. No reference
Potency (binding) = 56.2341 um PUBCHEM_BIOASSAY: qHTS Assay for Identification of Novel General Anesthetics. In this assay, a GABAergic mimetic model system, apoferritin and a profluorescent 1-aminoanthracene ligand (1-AMA), was used to construct a competitive binding assay for identification of novel general anesthetics (Class of assay: confirmatory) [Related pubchem assays: 2385 (Probe Development Summary for Identification of Novel General Anesthetics), 2323 (Validation apoferritin assay run on SigmaAldrich LOPAC1280 collection)] ChEMBL. No reference
Potency (functional) 89.1251 uM PUBCHEM_BIOASSAY: HTS for Inhibitors of HP1-beta Chromodomain Interactions with Methylated Histone Tails. (Class of assay: confirmatory) [Related pubchem assays (depositor defined):AID488962] ChEMBL. No reference
Potency (functional) 89.1251 uM PUBCHEM_BIOASSAY: qHTS Assay for the Inhibitors of Human Flap endonuclease 1 (FEN1). (Class of assay: confirmatory) [Related pubchem assays (depositor defined):AID488813] ChEMBL. No reference

Phenotypes

Whole-cell/tissue/organism interactions

We have no records of whole-cell/tissue assays done with this compound What does this mean?

Many chemical entities in TDR Targets come from high-throughput screenings with whole cells or tissue samples, and not all assayed compounds have been tested against a single a single target protein, probably because they get ruled out during screening process. Even if these compounds may have not been of interest in the original screening, they may come as interesting leads for other screening assays. Furthermore, we may be able to propose drug-target associations using chemical similarities and network patterns.

Annotated phenotypes:

We have no manually annotated phenotypes for this drug. What does this mean? / Care to help?
In TDR Targets, information about phenotypes that are caused by drugs, or by genetic manipulation of cells (e.g. gene knockouts or knockdowns) is manually curated from the literature. These descriptions help to describe the potential of the target for drug development. If no information is available for this gene or if the information is incomplete, this may mean that i) the papers containing this information either appeared after the curation effort for this organism was carried out or they were inadvertently missed by curators; or that ii) the curation effort for this organism has not yet started.
 
In any case, if you have information about papers containing relevant validation data for this target, please log in using your TDR Targets username and password and send them to us using the corresponding form in this page (only visible to registered users) or contact us.

External resources for this compound

Bibliographic References

No literature references available for this target.

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