Detailed information for compound 1341124

Basic information

Technical information
  • TDR Targets ID: 1341124
  • Name: (4-oxo-1,2,3-benzotriazin-3-yl)methyl cyclohe xanecarboxylate
  • MW: 287.314 | Formula: C15H17N3O3
  • H donors: 0 H acceptors: 2 LogP: 3.64 Rotable bonds: 4
    Rule of 5 violations (Lipinski): 1
  • SMILES: O=C(C1CCCCC1)OCn1nnc2c(c1=O)cccc2
  • InChi: 1S/C15H17N3O3/c19-14-12-8-4-5-9-13(12)16-17-18(14)10-21-15(20)11-6-2-1-3-7-11/h4-5,8-9,11H,1-3,6-7,10H2
  • InChiKey: SUILEKBBLIRPOY-UHFFFAOYSA-N  


Substructure search Similarity search

Network

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Synonyms

  • cyclohexanecarboxylic acid (4-oxo-1,2,3-benzotriazin-3-yl)methyl ester
  • cyclohexanecarboxylic acid (4-keto-1,2,3-benzotriazin-3-yl)methyl ester
  • BAS 03547982
  • Cyclohexanecarboxylic acid 4-oxo-4H-benzo[d][1,2,3]triazin-3-ylmethyl ester
  • ZINC00067132
  • Oprea1_371940
  • Oprea1_597924
  • MLS000054251
  • SMR000066195
  • T0507-7815

Targets

Known targets for this compound

Species Target name Source Bibliographic reference
Homo sapiens aldehyde dehydrogenase 1 family, member A1 Starlite/ChEMBL No references
Homo sapiens hydroxyprostaglandin dehydrogenase 15-(NAD) Starlite/ChEMBL No references
Bacillus anthracis Anthrax lethal factor Starlite/ChEMBL No references
Escherichia coli penicillin-binding protein Starlite/ChEMBL No references
Homo sapiens synuclein, alpha (non A4 component of amyloid precursor) Starlite/ChEMBL No references

Predicted pathogen targets for this compound

By orthology
Species Potential target Known druggable target/s Ortholog Group
Candida albicans aldehyde dehydrogenase Get druggable targets OG5_126638 All targets in OG5_126638
Echinococcus granulosus aldehyde dehydrogenase mitochondrial Get druggable targets OG5_126638 All targets in OG5_126638
Leishmania braziliensis aldehyde dehydrogenase, mitochondrial precursor Get druggable targets OG5_126638 All targets in OG5_126638
Mycobacterium tuberculosis Probable aldehyde dehydrogenase Get druggable targets OG5_126638 All targets in OG5_126638
Leishmania donovani aldehyde dehydrogenase, mitochondrial precursor Get druggable targets OG5_126638 All targets in OG5_126638
Candida albicans aldehyde dehydrogenase Get druggable targets OG5_126638 All targets in OG5_126638
Schistosoma japonicum Aldehyde dehydrogenase, mitochondrial precursor, putative Get druggable targets OG5_126638 All targets in OG5_126638
Schistosoma japonicum Aldehyde dehydrogenase X, mitochondrial precursor, putative Get druggable targets OG5_126638 All targets in OG5_126638
Toxoplasma gondii aldehyde dehydrogenase Get druggable targets OG5_126638 All targets in OG5_126638
Schistosoma japonicum ko:K00128 aldehyde dehydrogenase (NAD+) [EC1.2.1.3], putative Get druggable targets OG5_126638 All targets in OG5_126638
Leishmania mexicana aldehyde dehydrogenase, mitochondrial precursor Get druggable targets OG5_126638 All targets in OG5_126638
Schistosoma japonicum Retinal dehydrogenase 1, putative Get druggable targets OG5_126638 All targets in OG5_126638
Leishmania infantum aldehyde dehydrogenase, mitochondrial precursor Get druggable targets OG5_126638 All targets in OG5_126638
Echinococcus multilocularis aldehyde dehydrogenase, mitochondrial Get druggable targets OG5_126638 All targets in OG5_126638
Schistosoma mansoni aldehyde dehydrogenase Get druggable targets OG5_126638 All targets in OG5_126638
Candida albicans Mitochondrial aldehyde dehydrogenase Get druggable targets OG5_126638 All targets in OG5_126638
Neospora caninum hypothetical protein Get druggable targets OG5_126638 All targets in OG5_126638
Schistosoma mansoni aldehyde dehydrogenase Get druggable targets OG5_126638 All targets in OG5_126638
Mycobacterium ulcerans aldehyde dehydrogenase Get druggable targets OG5_126638 All targets in OG5_126638
Mycobacterium tuberculosis Possible penicillin-binding protein Get druggable targets OG5_149948 All targets in OG5_149948
Mycobacterium ulcerans aldehyde dehydrogenase Get druggable targets OG5_126638 All targets in OG5_126638
Mycobacterium ulcerans aldehyde dehydrogenase Get druggable targets OG5_126638 All targets in OG5_126638
Leishmania major aldehyde dehydrogenase, mitochondrial precursor Get druggable targets OG5_126638 All targets in OG5_126638
Candida albicans Mitochondrial aldehyde dehydrogenase Get druggable targets OG5_126638 All targets in OG5_126638
By sequence similarity to non orthologous known druggable targets
Species Potential target Known druggable target Length Alignment span Identity
Plasmodium falciparum steroid dehydrogenase, putative hydroxyprostaglandin dehydrogenase 15-(NAD) 266 aa 216 aa 22.2 %
Mycobacterium tuberculosis Succinate-semialdehyde dehydrogenase [NADP+] dependent (SSDH) GabD1 aldehyde dehydrogenase 1 family, member A1 501 aa 456 aa 33.3 %
Obtained from network model

Ranking Plot

Putative Targets List

Species Potential target Raw Global Species
Schistosoma mansoni hypothetical protein 0.0021 0.0009 0.006
Leishmania major acetyl-CoA synthetase, putative 0.0022 0.0011 0.001
Loa Loa (eye worm) hypothetical protein 0.0314 0.057 0.0606
Schistosoma mansoni histone deacetylase 0.0263 0.0473 0.3153
Trypanosoma cruzi serine carboxypeptidase S28, putative 0.004 0.0045 0.0046
Plasmodium vivax histone deacetylase, putative 0.01 0.0161 0.338
Echinococcus granulosus lysosomal alpha glucosidase 0.0339 0.0619 0.4121
Loa Loa (eye worm) hypothetical protein 0.0032 0.0031 0.0033
Echinococcus multilocularis lysosomal alpha glucosidase 0.0339 0.0619 0.0618
Plasmodium falciparum ataxin-2 like protein, putative 0.0026 0.0019 0.0361
Entamoeba histolytica glycosyl hydrolase, family 31 protein 0.0075 0.0113 0.1786
Loa Loa (eye worm) hypothetical protein 0.0069 0.0102 0.0108
Echinococcus granulosus p2X purinoceptor 4 0.0072 0.0106 0.0697
Brugia malayi MH2 domain containing protein 0.0251 0.0449 0.0477
Mycobacterium ulcerans epoxide hydrolase EphA 0.052 0.0966 0.1967
Loa Loa (eye worm) hypothetical protein 0.0019 0.0006 0.0007
Trypanosoma cruzi glycosyl hydrolase-like protein, putative 0.0028 0.0023 0.0022
Trichomonas vaginalis Clan SC, family S28, unassigned serine peptidase 0.004 0.0045 0.0684
Toxoplasma gondii transporter, cation channel family protein 0.0023 0.0013 0.0026
Loa Loa (eye worm) hypothetical protein 0.0023 0.0013 0.0014
Loa Loa (eye worm) hypothetical protein 0.0056 0.0076 0.0081
Trichomonas vaginalis lysosomal pro-X carboxypeptidase, putative 0.004 0.0045 0.0684
Toxoplasma gondii patched family protein 0.0019 0.0006 0.0013
Loa Loa (eye worm) patched family protein 0.0019 0.0006 0.0007
Brugia malayi Voltage-gated calcium channel, L-type, alpha subunit. C. elegans egl-19 ortholog 0.0023 0.0013 0.0014
Schistosoma mansoni ap endonuclease 0.0038 0.0042 0.0277
Echinococcus multilocularis DNA (apurinic or apyrimidinic site) lyase 0.0038 0.0042 0.004
Brugia malayi hypothetical protein 0.002 0.0008 0.0008
Schistosoma mansoni voltage-gated potassium channel 0.0023 0.0013 0.0085
Loa Loa (eye worm) hypothetical protein 0.0023 0.0012 0.0013
Schistosoma mansoni elf1 0.0021 0.0009 0.006
Onchocerca volvulus Steroid hormone receptor family member cnr14 homolog 0.0043 0.0051 0.0788
Trypanosoma cruzi PAB1-binding protein , putative 0.0026 0.0019 0.0018
Loa Loa (eye worm) histone deacetylase 0.0183 0.0319 0.0339
Loa Loa (eye worm) hypothetical protein 0.0055 0.0074 0.0079
Trypanosoma cruzi inositol 1,4,5-trisphosphate receptor, putative 0.0023 0.0013 0.0011
Loa Loa (eye worm) hypothetical protein 0.004 0.0045 0.0048
Loa Loa (eye worm) patched family protein 0.0019 0.0006 0.0007
Leishmania major pyruvate kinase 0.0036 0.0039 0.0039
Schistosoma mansoni Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) 0.0195 0.0342 0.2282
Echinococcus multilocularis diuretic hormone 44 receptor GPRdih2 0.0149 0.0255 0.0253
Onchocerca volvulus 0.0196 0.0345 0.601
Toxoplasma gondii hypothetical protein 0.0019 0.0006 0.0013
Echinococcus granulosus acetylcholinesterase 0.0069 0.0102 0.0666
Leishmania major alpha glucosidase II subunit, putative 0.0075 0.0113 0.0118
Echinococcus multilocularis pyruvate kinase 0.0036 0.0039 0.0037
Mycobacterium tuberculosis Possible penicillin-binding protein 0.1151 0.2175 0.4436
Schistosoma mansoni ferritin light chain 0.0018 0.0003 0.002
Loa Loa (eye worm) Smad1 0.0017 0.0002 0.0002
Trichomonas vaginalis chromodomain-helicase-DNA-binding protein, putative 0.002 0.0007 0.0058
Schistosoma mansoni RAR-like nuclear receptor 0.0043 0.0051 0.0337
Brugia malayi Corticotropin releasing factor receptor 2 precursor, putative 0.0471 0.0871 0.0926
Loa Loa (eye worm) hypothetical protein 0.0019 0.0006 0.0007
Schistosoma mansoni nuclear hormone receptor nor-1/nor-2 0.0043 0.0051 0.0337
Loa Loa (eye worm) hypothetical protein 0.009 0.0141 0.015
Trichomonas vaginalis voltage and ligand gated potassium channel, putative 0.0068 0.0099 0.1556
Schistosoma mansoni cyclic-nucleotide-gated cation channel 0.0023 0.0013 0.0085
Loa Loa (eye worm) hypothetical protein 0.018 0.0314 0.0334
Toxoplasma gondii histone lysine acetyltransferase GCN5-B 0.0046 0.0057 0.0116
Brugia malayi Patched family protein 0.0019 0.0006 0.0007
Loa Loa (eye worm) pyruvate kinase 0.0036 0.0039 0.0041
Brugia malayi Voltage-gated potassium channel, Shaw-family (KCNC, Kv3-like) alpha-subunit 0.0023 0.0013 0.0014
Trichomonas vaginalis histone deacetylase 1, 2 ,3, putative 0.0263 0.0473 0.7629
Entamoeba histolytica acyl-coA synthetase, putative 0.0075 0.0113 0.1776
Brugia malayi Glycosyl hydrolases family 31 protein 0.0028 0.0023 0.0024
Schistosoma mansoni nuclear receptor 0.002 0.0008 0.005
Brugia malayi Pyruvate kinase, M2 isozyme 0.0036 0.0039 0.0041
Echinococcus granulosus transient receptor potential cation channel 0.0023 0.0013 0.0074
Echinococcus granulosus transient receptor potential gamma protein 0.0023 0.0013 0.0074
Onchocerca volvulus 0.0022 0.0011 0.0088
Schistosoma mansoni cpg binding protein 0.0087 0.0135 0.0898
Loa Loa (eye worm) hypothetical protein 0.0023 0.0013 0.0014
Echinococcus multilocularis lamin 0.003 0.0027 0.0025
Brugia malayi Latrophilin receptor protein 2 0.0149 0.0255 0.027
Schistosoma mansoni voltage-gated potassium channel 0.0023 0.0013 0.0085
Toxoplasma gondii histone lysine methyltransferase SET1 0.017 0.0295 0.0601
Mycobacterium tuberculosis Possible fatty-acid-CoA ligase FadD10 (fatty-acid-CoA synthetase) (fatty-acid-CoA synthase) 0.0022 0.0011 0.0019
Echinococcus granulosus potassium voltage gated channel subfamily H 0.0091 0.0143 0.0941
Loa Loa (eye worm) D-ets-2 protein 0.0021 0.0009 0.001
Brugia malayi Hypothetical 52.5 kDa protein ZK945.1 in chromosome II, putative 0.018 0.0314 0.0334
Plasmodium vivax acetyl-CoA synthetase, putative 0.0022 0.0011 0.0193
Loa Loa (eye worm) nuclear hormone receptor family member nhr-1 0.0043 0.0051 0.0054
Echinococcus multilocularis histone lysine N methyltransferase MLL3 0.0027 0.002 0.0019
Plasmodium falciparum histone deacetylase, putative 0.0183 0.0319 0.6733
Loa Loa (eye worm) ion channel NompC 0.0023 0.0013 0.0014
Echinococcus granulosus FTZ F1 alpha 0.0043 0.0051 0.0327
Echinococcus granulosus two pore calcium channel protein 1 0.0023 0.0013 0.0074
Mycobacterium ulcerans phenyloxazoline synthase MbtB 0.0022 0.0011 0.0018
Trichomonas vaginalis Clan SC, family S28, unassigned serine peptidase 0.004 0.0045 0.0684
Schistosoma mansoni transient receptor potential cation channel subfamily m member 0.0023 0.0013 0.0085
Schistosoma mansoni hypothetical protein 0.0133 0.0223 0.1486
Schistosoma mansoni pyruvate kinase 0.0019 0.0005 0.0032
Echinococcus multilocularis GPCR, family 2 0.0149 0.0255 0.0253
Echinococcus multilocularis guanine nucleotide binding protein G(s) subunit 0.0195 0.0342 0.0341
Trichomonas vaginalis ap endonuclease, putative 0.0038 0.0042 0.0627
Trichomonas vaginalis pyruvate kinase, putative 0.0036 0.0039 0.0583
Trypanosoma cruzi hypothetical protein, conserved 0.0075 0.0113 0.0118
Schistosoma mansoni calcium channel voltage-dependent p/q type alpha 1a-related 0.0023 0.0013 0.0085
Trichomonas vaginalis Clan SC, family S28, unassigned serine peptidase 0.004 0.0045 0.0684
Echinococcus granulosus FTZ F1 nuclear receptor protein 0.0043 0.0051 0.0327
Schistosoma mansoni alpha-galactosidase/alpha-n-acetylgalactosaminidase 0.0076 0.0115 0.0768
Schistosoma mansoni P2X receptor subunit 0.0072 0.0106 0.0707
Onchocerca volvulus Transient receptor potential cation channel trpm homolog 0.0023 0.0013 0.0116
Plasmodium falciparum ATP-dependent 6-phosphofructokinase 0.0034 0.0034 0.068
Brugia malayi Fli-1 protein 0.0437 0.0807 0.0857
Brugia malayi nuclear hormone receptor 0.002 0.0008 0.0008
Mycobacterium leprae Probable pantoate--beta-alanine ligase PanC (pantothenate synthetase) (pantoate activating enzyme) 0.2573 0.4901 1
Echinococcus granulosus potassium voltage gated channel protein 0.0023 0.0013 0.0074
Trichomonas vaginalis phosphofructokinase, putative 0.0034 0.0034 0.0505
Entamoeba histolytica hypothetical protein 0.019 0.0334 0.5645
Loa Loa (eye worm) acetylcholinesterase 1 0.0069 0.0102 0.0108
Mycobacterium ulcerans acyl-CoA synthetase 0.0075 0.0113 0.0226
Loa Loa (eye worm) hypothetical protein 0.004 0.0045 0.0048
Schistosoma mansoni aldehyde dehydrogenase 0.0073 0.011 0.073
Onchocerca volvulus Transient receptor potential cation channel trpm homolog 0.0023 0.0013 0.0116
Brugia malayi hypothetical protein 0.0019 0.0006 0.0007
Echinococcus granulosus acetyl coenzyme A synthetase cytoplasmic 0.0022 0.0011 0.0063
Loa Loa (eye worm) hypothetical protein 0.0023 0.0013 0.0014
Mycobacterium ulcerans exodeoxyribonuclease III protein XthA 0.0038 0.0042 0.008
Mycobacterium ulcerans fatty-acid-CoA ligase 0.0056 0.0076 0.0151
Leishmania major glycosyl hydrolase-like protein 0.0028 0.0023 0.0022
Schistosoma mansoni cpg binding protein 0.0093 0.0148 0.0986
Trichomonas vaginalis conserved hypothetical protein 0.004 0.0045 0.0684
Trypanosoma cruzi polo-like protein kinase, putative 0.01 0.0161 0.0169
Onchocerca volvulus 0.018 0.0314 0.5462
Loa Loa (eye worm) nuclear hormone receptor family member nhr-14 0.0043 0.0051 0.0054
Echinococcus multilocularis bromodomain adjacent to zinc finger domain 0.0069 0.0102 0.01
Onchocerca volvulus 0.004 0.0045 0.069
Loa Loa (eye worm) hypothetical protein 0.0072 0.0107 0.0114
Trypanosoma brucei long-chain-fatty-acid-CoA ligase, putative 0.0022 0.0011 0.001
Trypanosoma brucei hypothetical protein, conserved 0.018 0.0314 0.0332
Trypanosoma brucei acetyl-CoA synthetase, putative 0.0022 0.0011 0.001
Loa Loa (eye worm) hypothetical protein 0.0019 0.0006 0.0007
Trichomonas vaginalis conserved hypothetical protein 0.002 0.0007 0.0058
Echinococcus granulosus hepatocyte nuclear factor 4 alpha 0.0043 0.0051 0.0327
Brugia malayi MH2 domain containing protein 0.0017 0.0002 0.0002
Trichomonas vaginalis antibiotic synthetase, putative 0.0022 0.0011 0.0133
Schistosoma mansoni ets-related 0.0021 0.0009 0.006
Loa Loa (eye worm) pyruvate kinase 0.0036 0.0039 0.0041
Loa Loa (eye worm) hypothetical protein 0.0023 0.0012 0.0013
Echinococcus granulosus potassium voltage gated channel subfamily H 0.0039 0.0044 0.0282
Schistosoma mansoni calcium-activated potassium channel 0.0023 0.0013 0.0085
Echinococcus multilocularis bromodomain adjacent to zinc finger domain 0.0037 0.0039 0.0037
Loa Loa (eye worm) hypothetical protein 0.0076 0.0114 0.0121
Loa Loa (eye worm) hypothetical protein 0.0023 0.0013 0.0014
Brugia malayi nuclear receptor NHR-67 0.002 0.0008 0.0008
Echinococcus granulosus histone lysine N methyltransferase MLL3 0.0027 0.002 0.0124
Brugia malayi olfactory channel protein osm-9 0.0023 0.0013 0.0014
Schistosoma mansoni hypothetical protein 0.0133 0.0223 0.1486
Trypanosoma cruzi histone deacetylase, putative 0.0183 0.0319 0.0337
Brugia malayi Ligand-binding domain of nuclear hormone receptor family protein 0.0043 0.0051 0.0054
Loa Loa (eye worm) hypothetical protein 0.0075 0.0113 0.012
Schistosoma mansoni histone deacetylase 1 2 3 0.01 0.0161 0.1075
Loa Loa (eye worm) hypothetical protein 0.0043 0.0051 0.0054
Trichomonas vaginalis helicase, putative 0.002 0.0007 0.0058
Brugia malayi Patched protein homolog 1 0.0019 0.0006 0.0007
Schistosoma mansoni tar DNA-binding protein 0.0063 0.009 0.0601
Echinococcus multilocularis histone deacetylase 0.0183 0.0319 0.0318
Onchocerca volvulus 0.0156 0.0268 0.4649
Trypanosoma brucei PAB1-binding protein , putative 0.0026 0.0019 0.0018
Mycobacterium tuberculosis Phenyloxazoline synthase MbtB (phenyloxazoline synthetase) 0.0022 0.0011 0.0019
Loa Loa (eye worm) hypothetical protein 0.002 0.0008 0.0008
Echinococcus multilocularis Glycoside hydrolase, family 27 0.0115 0.0189 0.0187
Trichomonas vaginalis alpha-glucosidase, putative 0.0075 0.0113 0.179
Schistosoma mansoni TGF-beta signal transducer Smad2 0.0017 0.0002 0.0011
Loa Loa (eye worm) hypothetical protein 0.0028 0.0023 0.0024
Loa Loa (eye worm) hypothetical protein 0.0023 0.0013 0.0014
Echinococcus granulosus Nuclear hormone receptor HR96 0.002 0.0008 0.0039
Echinococcus granulosus carboxylesterase 5A 0.0069 0.0102 0.0666
Echinococcus multilocularis protein dispatched 1 0.0157 0.027 0.0268
Loa Loa (eye worm) PLK/PLK1 protein kinase 0.01 0.0161 0.0171
Trypanosoma brucei apurinic/apyrimidinic endonuclease, putative 0.0038 0.0042 0.0042
Trichomonas vaginalis CAMK family protein kinase 0.005 0.0064 0.0988
Schistosoma mansoni alpha-glucosidase 0.0292 0.0529 0.3524
Echinococcus granulosus hypothetical protein 0.0023 0.0013 0.0074
Echinococcus granulosus transient receptor potential cation channel 0.0023 0.0013 0.0074
Trichomonas vaginalis phosphofructokinase, putative 0.0034 0.0034 0.0505
Schistosoma mansoni aldehyde dehydrogenase 0.0073 0.011 0.073
Loa Loa (eye worm) hypothetical protein 0.0052 0.0069 0.0073
Brugia malayi Voltage-gated potassium channel, HERG (KCNH2)-related. C. elegans unc-103 ortholog 0.0091 0.0143 0.0152
Mycobacterium ulcerans O-succinylbenzoic acid--CoA ligase 0.0022 0.0011 0.0018
Schistosoma mansoni hypothetical protein 0.0133 0.0223 0.1486
Brugia malayi latrophilin 2 splice variant baaae 0.0322 0.0586 0.0622
Mycobacterium ulcerans pyruvate kinase 0.0036 0.0039 0.0075
Mycobacterium leprae POSSIBLE FATTY-ACID-CoA LIGASE FADD10 (FATTY-ACID-CoA SYNTHETASE) (FATTY-ACID-CoA SYNTHASE) 0.0022 0.0011 0.0017
Mycobacterium ulcerans acyl-CoA synthetase 0.0022 0.0011 0.0018
Echinococcus multilocularis voltage dependent L type calcium channel subunit 0.0023 0.0013 0.0011
Schistosoma mansoni retinoid-x-receptor (RXR) 0.0043 0.0051 0.0337
Wolbachia endosymbiont of Brugia malayi exonuclease III 0.0038 0.0042 1
Onchocerca volvulus 0.0087 0.0135 0.228
Trichomonas vaginalis histone deacetylase 1, 2 ,3, putative 0.0263 0.0473 0.7629
Schistosoma mansoni ephrin receptor 0.0056 0.0075 0.0502
Loa Loa (eye worm) AMP-binding enzyme family protein 0.0022 0.0011 0.0012
Mycobacterium ulcerans long-chain fatty-acid CoA ligase 0.0075 0.0113 0.0226
Echinococcus multilocularis voltage dependent calcium channel 0.0023 0.0013 0.0011
Toxoplasma gondii histone lysine acetyltransferase GCN5-A 0.0046 0.0057 0.0116
Loa Loa (eye worm) hypothetical protein 0.0023 0.0013 0.0014
Trichomonas vaginalis CAMK family protein kinase 0.01 0.0161 0.2559
Brugia malayi hypothetical protein 0.0017 0.0001 0.0001
Brugia malayi Voltage-gated calcium channel, P/Q-type, alpha subunit. C. elegans unc-2 ortholog 0.0023 0.0013 0.0014
Schistosoma mansoni voltage-gated potassium channel 0.0097 0.0156 0.1036
Echinococcus multilocularis nuclear receptor 2DBD gamma 0.0043 0.0051 0.0049
Echinococcus multilocularis lysosomal alpha glucosidase 0.0339 0.0619 0.0618
Echinococcus multilocularis voltage gated hydrogen channel 1 0.0023 0.0013 0.0011
Echinococcus multilocularis ryanodine receptor 44f 0.0023 0.0013 0.0011
Schistosoma mansoni hypothetical protein 0.0322 0.0586 0.3904
Trichomonas vaginalis glucosylceramidase, putative 0.0185 0.0324 0.521
Treponema pallidum diphosphate--fructose-6-phosphate 1-phosphotransferase 0.0034 0.0034 0.1503
Schistosoma mansoni voltage-gated potassium channel 0.0023 0.0013 0.0085
Brugia malayi conserved hypotetical protein 0.002 0.0008 0.0008
Schistosoma mansoni NADP-specific isocitrate dehydrogenase 0.0017 0.0002 0.0014
Toxoplasma gondii exonuclease III APE 0.0038 0.0042 0.0085
Echinococcus granulosus potassium voltage gated channel subfamily A 0.0023 0.0013 0.0074
Echinococcus multilocularis voltage dependent L type calcium channel subunit 0.0023 0.0013 0.0011
Echinococcus multilocularis FTZ F1 alpha 0.0043 0.0051 0.0049
Entamoeba histolytica pyrophosphate-dependent phosphofructokinase 0.0034 0.0034 0.0401
Giardia lamblia Kinase, PLK 0.01 0.0161 0.3328
Entamoeba histolytica acyl-CoA synthetase, putative 0.0075 0.0113 0.1776
Brugia malayi steroid hormone receptor 0.0043 0.0051 0.0054
Loa Loa (eye worm) hypothetical protein 0.0023 0.0012 0.0013
Loa Loa (eye worm) nuclear receptor NHR-67 0.002 0.0008 0.0008
Loa Loa (eye worm) hypothetical protein 0.0082 0.0127 0.0135
Schistosoma mansoni hypothetical protein 0.0156 0.0268 0.1789
Mycobacterium tuberculosis Probable chain -fatty-acid-CoA ligase FadD13 (fatty-acyl-CoA synthetase) 0.0075 0.0113 0.0226
Echinococcus multilocularis hyperpolarization activated cyclic 0.0032 0.0031 0.0029
Trypanosoma brucei Voltage-dependent calcium channel subunit, putative 0.0023 0.0013 0.0011
Echinococcus granulosus dnaJ subfamily B 0.0799 0.15 1
Brugia malayi Ligand-binding domain of nuclear hormone receptor family protein 0.0043 0.0051 0.0054
Schistosoma mansoni voltage-dependent calcium channel 0.0023 0.0013 0.0085
Schistosoma mansoni hypothetical protein 0.0133 0.0223 0.1486
Loa Loa (eye worm) hypothetical protein 0.0021 0.0009 0.001
Brugia malayi TAR-binding protein 0.0063 0.009 0.0096
Schistosoma mansoni hypothetical protein 0.0149 0.0255 0.1696
Loa Loa (eye worm) hypothetical protein 0.0019 0.0006 0.0007
Echinococcus multilocularis Nuclear hormone receptor HR96 0.002 0.0008 0.0006
Trichomonas vaginalis glucosylceramidase, putative 0.0185 0.0324 0.521
Echinococcus multilocularis ets variant gene 4 0.0021 0.0009 0.0007
Brugia malayi calcium-independent alpha-latrotoxin receptor 2, putative 0.0149 0.0255 0.027
Loa Loa (eye worm) hypothetical protein 0.0043 0.0051 0.0054
Schistosoma mansoni ets-related 0.0437 0.0807 0.5379
Mycobacterium leprae PROBABLE FATTY-ACID-CoA LIGASE FADD7 (FATTY-ACID-CoA SYNTHETASE) (FATTY-ACID-CoA SYNTHASE) 0.0075 0.0113 0.0224
Trypanosoma cruzi PAB1-binding protein , putative 0.0026 0.0019 0.0018
Trichomonas vaginalis histone deacetylase, putative 0.0263 0.0473 0.7629
Schistosoma mansoni ets 0.0021 0.0009 0.006
Brugia malayi beta-lactamase family protein 0.018 0.0314 0.0334
Loa Loa (eye worm) hypothetical protein 0.0019 0.0006 0.0007
Schistosoma mansoni tar DNA-binding protein 0.0063 0.009 0.0601
Loa Loa (eye worm) hypothetical protein 0.0023 0.0013 0.0014
Echinococcus multilocularis pyruvate kinase 0.0019 0.0005 0.0003
Brugia malayi hypothetical protein 0.0766 0.1437 0.1527
Brugia malayi Ets-domain containing protein 0.0144 0.0245 0.026
Giardia lamblia Pyrophosphate-fructose 6-phosphate 1-phosphotransferase alpha subunit 0.0034 0.0034 0.0624
Echinococcus granulosus voltage dependent calcium channel type d subunit|voltage dependent calcium channel alpha 1 0.0023 0.0013 0.0074
Plasmodium falciparum lipid/sterol:H+ symporter 0.0019 0.0006 0.0087
Echinococcus granulosus potassium large conductance calcium activated 0.0023 0.0013 0.0074
Schistosoma mansoni voltage-gated potassium channel 0.0023 0.0013 0.0085
Schistosoma mansoni ferritin 0.0018 0.0003 0.002
Onchocerca volvulus 0.002 0.0008 0.0023
Brugia malayi Voltage-gated calcium channel, alpha subunit 0.0023 0.0013 0.0014
Loa Loa (eye worm) pyruvate kinase-PB 0.0025 0.0018 0.0019
Echinococcus granulosus neutral alpha glucosidase AB 0.0075 0.0113 0.0745
Schistosoma mansoni smad1 5 8 and 0.0017 0.0002 0.0011
Brugia malayi hypothetical protein 0.0019 0.0006 0.0007
Schistosoma mansoni two-pore calcium channel 0.0023 0.0013 0.0085
Schistosoma mansoni alpha-galactosidase/alpha-n-acetylgalactosaminidase 0.0115 0.0189 0.1256
Echinococcus granulosus histone acetyltransferase KAT2B 0.0046 0.0057 0.0368
Brugia malayi Pyruvate kinase, muscle isozyme 0.0036 0.0039 0.0041
Trichomonas vaginalis glucosylceramidase, putative 0.0282 0.051 0.823
Loa Loa (eye worm) hypothetical protein 0.0056 0.0076 0.0081
Echinococcus granulosus sterol regulatory element binding protein 0.0137 0.0232 0.154
Echinococcus multilocularis histone deacetylase 6 0.0183 0.0319 0.0318
Schistosoma mansoni transient receptor potential channel 0.0023 0.0013 0.0085
Echinococcus granulosus potassium voltage gated channel protein 0.0023 0.0013 0.0074
Echinococcus multilocularis potassium voltage gated channel subfamily D 0.0023 0.0013 0.0011
Loa Loa (eye worm) hypothetical protein 0.0023 0.0013 0.0014
Trypanosoma cruzi long-chain-fatty-acid-CoA ligase, putative 0.0022 0.0011 0.001
Echinococcus granulosus diuretic hormone 44 receptor GPRdih2 0.0149 0.0255 0.1687
Trichomonas vaginalis alpha-glucosidase, putative 0.0028 0.0023 0.0321
Echinococcus multilocularis 6 phosphofructokinase 0.0126 0.021 0.0208
Schistosoma mansoni alpha-galactosidase/alpha-n-acetylgalactosaminidase 0.0115 0.0189 0.1256
Mycobacterium leprae Possible short-chain dehydrogenase EphD 0.0019 0.0005 0.0005
Trichomonas vaginalis phosphofructokinase, putative 0.0126 0.021 0.336
Schistosoma mansoni nuclear hormone receptor 0.002 0.0008 0.005
Echinococcus multilocularis tar DNA binding protein 0.0063 0.009 0.0089
Trypanosoma cruzi Voltage-dependent calcium channel subunit, putative 0.0023 0.0013 0.0011
Trichomonas vaginalis glucosylceramidase, putative 0.0195 0.0343 0.5521
Trichomonas vaginalis glucosylceramidase, putative 0.0282 0.051 0.823
Echinococcus multilocularis histone deacetylase 3 0.0263 0.0473 0.0472
Brugia malayi nuclear hormone receptor 0.0043 0.0051 0.0054
Trichomonas vaginalis conserved hypothetical protein 0.004 0.0045 0.0684
Loa Loa (eye worm) hypothetical protein 0.0362 0.0663 0.0704
Trypanosoma brucei histone deacetylase 1 0.0263 0.0473 0.0501
Echinococcus granulosus potassium voltage gated channel subfamily D 0.0023 0.0013 0.0074
Mycobacterium ulcerans beta-lactamase 0.018 0.0314 0.0637
Echinococcus multilocularis Lysosomal Pro X carboxypeptidase 0.074 0.1387 0.1385
Echinococcus multilocularis transient receptor potential cation channel 0.0023 0.0013 0.0011
Loa Loa (eye worm) hypothetical protein 0.0766 0.1437 0.1527
Brugia malayi Histone deacetylase family protein 0.0183 0.0319 0.0339
Mycobacterium ulcerans acyl-CoA synthetase 0.0075 0.0113 0.0226
Trypanosoma brucei histone deacetylase 4 0.0183 0.0319 0.0337
Mycobacterium tuberculosis Probable fatty-acid-CoA ligase FadD7 (fatty-acid-CoA synthetase) (fatty-acid-CoA synthase) 0.0053 0.0071 0.014
Brugia malayi nuclear hormone receptor family member odr-7 0.002 0.0008 0.0008
Echinococcus granulosus guanine nucleotide binding protein Gs subunit 0.0195 0.0342 0.2273
Loa Loa (eye worm) hypothetical protein 0.01 0.0161 0.0171
Trichomonas vaginalis pyruvate kinase, putative 0.0036 0.0039 0.0583
Mycobacterium tuberculosis Possible fatty-acid-CoA ligase FadD1 (fatty-acid-CoA synthetase) (fatty-acid-CoA synthase) 0.0022 0.0011 0.0019
Brugia malayi Nuclear hormone receptor family member nhr-1 0.0043 0.0051 0.0054
Entamoeba histolytica glycosyl hydrolase, family 31 protein 0.0028 0.0023 0.0202
Trichomonas vaginalis CAMK family protein kinase 0.01 0.0161 0.2559
Entamoeba histolytica pyruvate kinase, putative 0.0025 0.0018 0.0115
Schistosoma mansoni family S12 unassigned peptidase (S12 family) 0.018 0.0314 0.2094
Trichomonas vaginalis prolylcarboxypeptidase, putative 0.004 0.0045 0.0684
Loa Loa (eye worm) hypothetical protein 0.0023 0.0013 0.0014
Brugia malayi voltage-dependent calcium channel 0.0023 0.0013 0.0014
Echinococcus granulosus serine:threonine protein kinase PLK1 0.01 0.0161 0.1061
Brugia malayi beta-lactamase family protein 0.018 0.0314 0.0334
Schistosoma mansoni Smad4 0.0017 0.0002 0.0011
Mycobacterium tuberculosis Probable fatty-acid-CoA ligase FadD3 (fatty-acid-CoA synthetase) (fatty-acid-CoA synthase) 0.0053 0.0071 0.014
Echinococcus multilocularis sodium channel protein 0.0023 0.0013 0.0011
Schistosoma mansoni transcription factor LCR-F1 0.019 0.0334 0.2225
Entamoeba histolytica serine carboxypeptidase (S28) family protein 0.004 0.0045 0.0594
Loa Loa (eye worm) D-ets-4 DNA binding domain-containing protein 0.0144 0.0245 0.026
Echinococcus granulosus Basic leucine zipper bZIP transcription 0.019 0.0334 0.2217
Echinococcus granulosus pyruvate kinase 0.0019 0.0005 0.0021
Onchocerca volvulus Histone deacetylase 10 homolog 0.01 0.0161 0.275
Echinococcus granulosus DNA apurinic or apyrimidinic site lyase 0.0038 0.0042 0.0266
Loa Loa (eye worm) hypothetical protein 0.0019 0.0006 0.0007
Leishmania major histone deacetylase, putative 0.0183 0.0319 0.0337
Loa Loa (eye worm) hypothetical protein 0.0019 0.0006 0.0007
Entamoeba histolytica histone deacetylase, putative 0.0263 0.0473 0.8081
Echinococcus granulosus ferritin 0.0018 0.0003 0.0009
Loa Loa (eye worm) hypothetical protein 0.0019 0.0006 0.0007
Echinococcus multilocularis histone deacetylase 6 0.0183 0.0319 0.0318
Schistosoma mansoni 60S ribosomal protein L21 0.003 0.0026 0.017
Toxoplasma gondii patched family protein 0.0019 0.0006 0.0013
Echinococcus multilocularis hyperpolarization activated cyclic 0.0032 0.0031 0.0029
Loa Loa (eye worm) hypothetical protein 0.0043 0.0051 0.0054
Loa Loa (eye worm) hypothetical protein 0.0056 0.0076 0.0081
Echinococcus granulosus pyruvate kinase 0.0036 0.0039 0.0248
Trichomonas vaginalis histone deacetylase, putative 0.0263 0.0473 0.7629
Leishmania major 4-coumarate:coa ligase-like protein 0.0075 0.0113 0.0118
Loa Loa (eye worm) hypothetical protein 0.0075 0.0113 0.012
Trichomonas vaginalis neutral alpha-glucosidase ab precursor, putative 0.0075 0.0113 0.179
Loa Loa (eye worm) carboxylesterase 0.0069 0.0102 0.0108
Echinococcus granulosus transient receptor potential cation channel 0.0023 0.0013 0.0074
Echinococcus granulosus cyclic nucleotide gated cation channel 0.0032 0.0031 0.0196
Brugia malayi exodeoxyribonuclease III family protein 0.0038 0.0042 0.0044
Echinococcus multilocularis sterol regulatory element binding protein 0.0137 0.0232 0.0231
Brugia malayi Serine carboxypeptidase S28 family protein 0.004 0.0045 0.0048
Trichomonas vaginalis chromodomain helicase DNA binding protein, putative 0.002 0.0007 0.0058
Schistosoma mansoni serine/threonine protein kinase 0.01 0.0161 0.1071
Trypanosoma cruzi apurinic/apyrimidinic endonuclease, putative 0.0038 0.0042 0.0042
Echinococcus multilocularis transient receptor potential cation channel 0.0023 0.0013 0.0011
Onchocerca volvulus 0.0055 0.0074 0.1206
Schistosoma mansoni voltage-gated potassium channel 0.0023 0.0013 0.0085
Trichomonas vaginalis CAMK family protein kinase 0.01 0.0161 0.2559
Trichomonas vaginalis Clan SC, family S28, unassigned serine peptidase 0.004 0.0045 0.0684
Trichomonas vaginalis glucosylceramidase, putative 0.0282 0.051 0.823
Toxoplasma gondii LsmAD domain-containing protein 0.0026 0.0019 0.0039
Brugia malayi Nuclear hormone receptor family member nhr-25 0.0043 0.0051 0.0054
Echinococcus granulosus ETS domain containing protein Elk 1 0.0021 0.0009 0.0049
Trichomonas vaginalis maltase-glucoamylase, putative 0.0028 0.0023 0.0321
Toxoplasma gondii phosphofructokinase domain-containing protein 0.0034 0.0034 0.007
Brugia malayi Cyclic-nucleotide gated cation channel 0.0032 0.0031 0.0033
Mycobacterium leprae Probable lipase LipE 0.018 0.0314 0.0636
Loa Loa (eye worm) hypothetical protein 0.002 0.0008 0.0008
Schistosoma mansoni lamin 0.003 0.0027 0.0178
Schistosoma mansoni hypothetical protein 0.0537 0.0997 0.6647
Schistosoma mansoni histone deacetylase hda2 0.0183 0.0319 0.2128
Echinococcus multilocularis retinoic acid receptor rxr beta a retinoic acid receptor rxr alpha a retinoic acid receptor rxr alpha 0.002 0.0008 0.0006
Loa Loa (eye worm) MH2 domain-containing protein 0.0017 0.0002 0.0002
Echinococcus multilocularis voltage dependent calcium channel type d subunit 0.0023 0.0013 0.0011
Echinococcus granulosus bromodomain adjacent to zinc finger domain 0.0069 0.0102 0.0667
Echinococcus multilocularis voltage dependent calcium channel 0.0023 0.0013 0.0011
Loa Loa (eye worm) hypothetical protein 0.0471 0.0871 0.0926
Mycobacterium ulcerans lipase LipD 0.018 0.0314 0.0637
Trichomonas vaginalis chromodomain helicase DNA binding protein, putative 0.002 0.0007 0.0058
Schistosoma mansoni voltage-gated potassium channel 0.0023 0.0013 0.0085
Echinococcus granulosus pyruvate kinase 0.0019 0.0005 0.0021
Toxoplasma gondii ABC1 family protein 0.018 0.0314 0.0641
Schistosoma mansoni Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) 0.0195 0.0342 0.2282
Brugia malayi Nuclear hormone receptor family member nhr-40 0.0043 0.0051 0.0054
Brugia malayi Patched family protein 0.0019 0.0006 0.0007
Plasmodium falciparum histone deacetylase 1 0.0263 0.0473 1
Onchocerca volvulus 0.0023 0.0013 0.0116
Brugia malayi cation channel family protein 0.0023 0.0013 0.0014
Trichomonas vaginalis glucosylceramidase, putative 0.0282 0.051 0.823
Entamoeba histolytica serine/threonine protein kinase, putative 0.01 0.0161 0.2616
Echinococcus granulosus lamin 0.003 0.0027 0.0167
Loa Loa (eye worm) hypothetical protein 0.2519 0.4796 0.5095
Loa Loa (eye worm) hypothetical protein 0.002 0.0008 0.0008
Schistosoma mansoni histone-lysine n-methyltransferase setb1 0.0019 0.0006 0.0039
Brugia malayi Isocitrate dehydrogenase 0.0017 0.0002 0.0002
Trichomonas vaginalis phosphofructokinase, putative 0.0126 0.021 0.336
Loa Loa (eye worm) DNA-binding protein D-ETS-3 0.0021 0.0009 0.001
Loa Loa (eye worm) hypothetical protein 0.0081 0.0125 0.0132
Schistosoma mansoni transient receptor potential channel 0.0023 0.0013 0.0085
Brugia malayi Steroid receptor seven-up type 2 0.0043 0.0051 0.0054
Echinococcus granulosus bromodomain adjacent to zinc finger domain 0.0037 0.0039 0.0249
Loa Loa (eye worm) hypothetical protein 0.002 0.0008 0.0008
Trichomonas vaginalis chromodomain helicase DNA binding protein, putative 0.002 0.0007 0.0058
Echinococcus granulosus histone deacetylase 3 0.0263 0.0473 0.3146
Schistosoma mansoni transient receptor potential cation channel subfamily m member 0.0023 0.0013 0.0085
Brugia malayi 6-phosphofructokinase 0.0126 0.021 0.0223
Plasmodium vivax 6-phosphofructokinase, putative 0.0034 0.0034 0.068
Loa Loa (eye worm) hypothetical protein 0.0023 0.0013 0.0014
Brugia malayi O-Glycosyl hydrolase family 30 protein 0.0282 0.051 0.0542
Loa Loa (eye worm) hypothetical protein 0.003 0.0027 0.0029
Trypanosoma cruzi serine carboxypeptidase S28, putative 0.004 0.0045 0.0046
Brugia malayi Nuclear hormone receptor family member nhr-25 0.0043 0.0051 0.0054
Trypanosoma cruzi putative prolyl carboxypeptidase, putative 0.004 0.0045 0.0046
Loa Loa (eye worm) hypothetical protein 0.004 0.0045 0.0048
Schistosoma mansoni Tr4/Tr2 (homologue) 0.0043 0.0051 0.0337
Echinococcus granulosus Niemann Pick C1 protein 0.032 0.0583 0.3878
Schistosoma mansoni hypothetical protein 0.019 0.0334 0.2225
Mycobacterium ulcerans aldehyde dehydrogenase 0.0073 0.011 0.0219
Schistosoma mansoni 6-phosphofructokinase 0.0126 0.021 0.14
Echinococcus multilocularis pyruvate kinase 0.0019 0.0005 0.0003
Leishmania major acetyl-CoA synthetase, putative 0.0022 0.0011 0.001
Echinococcus multilocularis Basic leucine zipper (bZIP) transcription 0.019 0.0334 0.0332
Schistosoma mansoni retinoid-x-receptor (RXR) 0.0023 0.0012 0.0081
Schistosoma mansoni smad 0.0017 0.0002 0.0011
Loa Loa (eye worm) glycosyl hydrolase family 31 protein 0.0075 0.0113 0.012
Toxoplasma gondii 6-phosphofructokinase 0.0034 0.0034 0.007
Schistosoma mansoni nAChR subunit (ShAR1-alpha-like) 0.0081 0.0125 0.083
Brugia malayi hypothetical protein 0.0019 0.0006 0.0007
Schistosoma mansoni retinoic acid receptor RXR 0.0043 0.0051 0.0337
Echinococcus granulosus ETS transcription factor Elf 2 0.0021 0.0009 0.0049
Entamoeba histolytica phosphofructokinase, putative 0.0126 0.021 0.3478
Toxoplasma gondii transporter, cation channel family protein 0.0023 0.0013 0.0026
Entamoeba histolytica serine carboxypeptidase (S28) family protein 0.004 0.0045 0.0594
Chlamydia trachomatis acylglycerophosphoethanolamine acyltransferase 0.0056 0.0076 1
Schistosoma mansoni pyruvate kinase 0.0036 0.0039 0.0259
Brugia malayi Nuclear hormone receptor E75 0.002 0.0008 0.0008
Trichomonas vaginalis neutral alpha-glucosidase ab precursor, putative 0.0028 0.0023 0.0321
Onchocerca volvulus 0.0022 0.0011 0.0088
Schistosoma mansoni bromodomain containing protein 0.0073 0.0109 0.0724
Brugia malayi nuclear receptor RXR 0.0023 0.0012 0.0013
Onchocerca volvulus 0.003 0.0027 0.0365
Schistosoma mansoni polyomavirus enhancer activator 3 pea3 0.0021 0.0009 0.006
Brugia malayi F/Y-rich N-terminus family protein 0.0028 0.0023 0.0025
Brugia malayi Nuclear hormone receptor family member nhr-14 0.0043 0.0051 0.0054
Loa Loa (eye worm) hypothetical protein 0.002 0.0008 0.0008
Echinococcus multilocularis zinc finger protein 0.0028 0.0024 0.0022
Loa Loa (eye worm) hypothetical protein 0.0019 0.0006 0.0007
Brugia malayi Voltage-gated potassium channel, Shaker-family (KCNA, Kv1-like) alpha-subunit 0.0023 0.0013 0.0014
Loa Loa (eye worm) hypothetical protein 0.0019 0.0006 0.0007
Echinococcus granulosus expressed conserved protein 0.0301 0.0546 0.3629
Brugia malayi transcription factor E74 isoform 0.0021 0.0009 0.001
Entamoeba histolytica phosphofructokinase, putative 0.0126 0.021 0.3478
Schistosoma mansoni nuclear hormone receptor 0.002 0.0008 0.005
Brugia malayi Nuclear hormone receptor family member nhr-31 0.0043 0.0051 0.0054
Schistosoma mansoni voltage-gated cation channel 0.0023 0.0013 0.0085
Mycobacterium tuberculosis Probable lipase LipE 0.018 0.0314 0.0637
Brugia malayi Bromodomain containing protein 0.0085 0.0132 0.014
Trichomonas vaginalis glucosylceramidase, putative 0.0185 0.0324 0.521
Echinococcus multilocularis histone deacetylase 7 0.0183 0.0319 0.0318
Mycobacterium leprae Probable fatty-acid-CoA synthetase FadD22 (fatty-acid-CoA ligase) (fatty-acid-CoA synthase) 0.0022 0.0011 0.0017
Trypanosoma cruzi histone deacetylase 1, putative 0.0263 0.0473 0.0501
Brugia malayi AMP-binding enzyme family protein 0.0022 0.0011 0.0012
Trichomonas vaginalis conserved hypothetical protein 0.0339 0.0619 1
Schistosoma mansoni 6-phosphofructokinase 0.0126 0.021 0.14
Loa Loa (eye worm) hypothetical protein 0.0023 0.0013 0.0014
Leishmania major long-chain-fatty-acid-CoA ligase, putative 0.0022 0.0011 0.001
Trichomonas vaginalis Clan SC, family S28, unassigned serine peptidase 0.004 0.0045 0.0684
Entamoeba histolytica phosphofructokinase, putative 0.0126 0.021 0.3478
Mycobacterium ulcerans acyl-CoA synthetase 0.0022 0.0011 0.0018
Echinococcus granulosus sodium channel protein 0.0023 0.0013 0.0074
Plasmodium vivax patched family protein, putative 0.0019 0.0006 0.0087
Loa Loa (eye worm) hypothetical protein 0.0036 0.0039 0.0041
Echinococcus multilocularis potassium voltage gated channel subfamily A 0.0023 0.0013 0.0011
Trichomonas vaginalis D-aminoacylase, putative 0.018 0.0314 0.505
Loa Loa (eye worm) hypothetical protein 0.018 0.0314 0.0334
Giardia lamblia Serine peptidase, putative 0.004 0.0045 0.086
Plasmodium vivax hypothetical protein, conserved 0.018 0.0314 0.6626
Echinococcus granulosus mixed lineage leukemia protein mll 0.0021 0.001 0.0057
Toxoplasma gondii Acetyl-coenzyme A synthetase 2, putative 0.0022 0.0011 0.0023
Trypanosoma cruzi glycosyl hydrolase-like protein, putative 0.0028 0.0023 0.0022
Onchocerca volvulus Bile acid receptor homolog 0.0043 0.0051 0.0788
Trichomonas vaginalis phosphofructokinase, putative 0.0034 0.0034 0.0505
Schistosoma mansoni voltage-gated potassium channel KCNQ 0.0023 0.0013 0.0085
Schistosoma mansoni acetyl-CoA C-acetyltransferase 0.0028 0.0022 0.0149
Schistosoma mansoni voltage-gated potassium channel 0.0097 0.0156 0.1036
Plasmodium falciparum pyruvate kinase 0.0036 0.0039 0.0781
Plasmodium vivax histone deacetylase, putative 0.0183 0.0319 0.6733
Loa Loa (eye worm) TAR-binding protein 0.0063 0.009 0.0096
Schistosoma mansoni transient receptor potential cation channel subfamily m member 0.0023 0.0013 0.0085
Echinococcus multilocularis two pore calcium channel protein 1 0.0023 0.0013 0.0011
Brugia malayi Myosin head containing protein 0.0019 0.0006 0.0007
Brugia malayi DNA-binding protein D-ETS-3 0.0021 0.0009 0.001
Trypanosoma brucei polo-like protein kinase 0.01 0.0161 0.0169
Echinococcus granulosus histone acetyltransferase KAT2B 0.0144 0.0244 0.1618
Echinococcus multilocularis two pore calcium channel protein 2 0.0023 0.0013 0.0011
Toxoplasma gondii isocitrate dehydrogenase 0.0017 0.0002 0.0004
Echinococcus granulosus GPCR family 2 0.0149 0.0255 0.1687
Echinococcus granulosus p2X purinoceptor 4 0.0072 0.0106 0.0697
Brugia malayi Voltage-gated potassium channel, KCNQ (Kv7-like) alpha-subunit. C. elegans kqt-1 ortholog 0.0023 0.0013 0.0014
Toxoplasma gondii histone deacetylase HDAC5 0.01 0.0161 0.0329
Trypanosoma cruzi histone deacetylase, putative 0.01 0.0161 0.0169
Toxoplasma gondii histone deacetylase HDAC1 0.0183 0.0319 0.0651
Brugia malayi nuclear receptor NHR-88 0.0043 0.0051 0.0054
Schistosoma mansoni voltage-gated potassium channel 0.0039 0.0044 0.0292
Mycobacterium tuberculosis Conserved protein 0.018 0.0314 0.0637
Leishmania major C-8 sterol isomerase-like protein 0.4928 0.9414 1
Trichomonas vaginalis conserved hypothetical protein 0.002 0.0007 0.0058
Echinococcus granulosus pyruvate kinase 0.0019 0.0005 0.0021
Plasmodium falciparum histone acetyltransferase GCN5 0.004 0.0045 0.0917
Loa Loa (eye worm) voltage-dependent calcium channel 0.0023 0.0013 0.0014
Trichomonas vaginalis conserved hypothetical protein 0.002 0.0007 0.0058
Schistosoma mansoni family S28 unassigned peptidase (S28 family) 0.074 0.1387 0.9241
Trichomonas vaginalis Clan SC, family S28, unassigned serine peptidase 0.004 0.0045 0.0684
Echinococcus multilocularis hepatocyte nuclear factor 4 alpha 0.0043 0.0051 0.0049
Schistosoma mansoni gcn5proteinral control of amino-acid synthesis 5-like 2 gcnl2 0.015 0.0257 0.1711
Brugia malayi nuclear receptor subfamily 1, group D, member 1, putative 0.002 0.0008 0.0008
Schistosoma mansoni zinc finger protein 0.0028 0.0024 0.0156
Trypanosoma cruzi hypothetical protein, conserved 0.0075 0.0113 0.0118
Schistosoma mansoni mixed-lineage leukemia protein mll 0.0184 0.0321 0.2137
Echinococcus multilocularis thyroid hormone receptor alpha 0.0043 0.0051 0.0049
Giardia lamblia Histone deacetylase 0.0263 0.0473 1
Loa Loa (eye worm) hypothetical protein 0.0019 0.0006 0.0007
Mycobacterium ulcerans fusion of enoyl-CoA hydratase, EchA21 and lipase, LipE 0.018 0.0314 0.0637
Trichomonas vaginalis alpha-glucosidase, putative 0.0028 0.0023 0.0321
Echinococcus granulosus transient receptor potential cation channel 0.0023 0.0013 0.0074
Mycobacterium tuberculosis Peptide synthetase MbtE (peptide synthase) 0.0022 0.0011 0.0019
Echinococcus granulosus potassium voltage gated channel subfamily C 0.0023 0.0013 0.0074
Echinococcus granulosus histone deacetylase 1 0.0263 0.0473 0.3146
Trichomonas vaginalis conserved hypothetical protein 0.002 0.0007 0.0058
Mycobacterium ulcerans aldehyde dehydrogenase 0.0073 0.011 0.0219
Schistosoma mansoni eyes absent homolog 0.009 0.0141 0.0938
Loa Loa (eye worm) acetyltransferase 0.015 0.0257 0.0273
Leishmania major calcium channel protein, putative,ion transporter, putative 0.0023 0.0013 0.0011
Brugia malayi Bromodomain containing protein 0.0043 0.0051 0.0054
Echinococcus multilocularis nuclear receptor 2DBD gamma 0.002 0.0008 0.0006
Loa Loa (eye worm) cyclic-nucleotide gated cation channel 0.0032 0.0031 0.0033
Toxoplasma gondii hypothetical protein 0.0023 0.0013 0.0026
Schistosoma mansoni voltage-gated potassium channel 0.0039 0.0044 0.0292
Brugia malayi protein C24B5.3 0.0019 0.0006 0.0007
Onchocerca volvulus 0.0043 0.0051 0.0788
Loa Loa (eye worm) hypothetical protein 0.0019 0.0006 0.0007
Mycobacterium tuberculosis Fatty-acid-CoA synthetase FadD17 (fatty-acid-CoA synthase) (fatty-acid-CoA ligase) 0.0022 0.0011 0.0019
Echinococcus granulosus transient receptor potential cation channel 0.0023 0.0013 0.0074
Brugia malayi hypothetical protein 0.019 0.0334 0.0355
Loa Loa (eye worm) cyclic-nucleotide gated cation channel 0.0032 0.0031 0.0033
Echinococcus granulosus histone deacetylase 7 0.0183 0.0319 0.2119
Echinococcus multilocularis TRP (transient receptor potential) channel 0.0023 0.0013 0.0011
Brugia malayi Nuclear hormone receptor family member nhr-49 0.0043 0.0051 0.0054
Brugia malayi Nuclear hormone receptor E75 0.002 0.0008 0.0008
Trichomonas vaginalis alpha-glucosidase, putative 0.0028 0.0023 0.0321
Trichomonas vaginalis histone deacetylase, putative 0.0263 0.0473 0.7629
Mycobacterium ulcerans non-ribosomal peptide synthetase MbtF 0.0022 0.0011 0.0018
Echinococcus granulosus histone deacetylase 6 0.0183 0.0319 0.2119
Brugia malayi GTP-binding regulatory protein Gs alpha-S chain, putative 0.0195 0.0342 0.0364
Loa Loa (eye worm) hypothetical protein 0.0149 0.0255 0.027
Loa Loa (eye worm) hypothetical protein 0.0019 0.0006 0.0007
Echinococcus multilocularis transient receptor potential cation channel 0.0023 0.0013 0.0011
Brugia malayi 6-phosphofructokinase 0.0126 0.021 0.0223
Brugia malayi Carboxylesterase family protein 0.0069 0.0102 0.0108
Echinococcus multilocularis potassium voltage gated channel subfamily D 0.0023 0.0013 0.0011
Brugia malayi MH1 domain containing protein 0.0017 0.0002 0.0002
Mycobacterium tuberculosis Probable epoxide hydrolase EphA (epoxide hydratase) (arene-oxide hydratase) 0.052 0.0966 0.1967
Brugia malayi ion channel NompC 0.0023 0.0013 0.0014
Echinococcus granulosus cyclic nucleotide gated cation channel 0.0032 0.0031 0.0196
Brugia malayi Glycosyl hydrolases family 31 protein 0.0339 0.0619 0.0658
Schistosoma mansoni family S12 unassigned peptidase (S12 family) 0.018 0.0314 0.2094
Brugia malayi Nuclear hormone receptor family member nhr-41 0.0043 0.0051 0.0054
Echinococcus granulosus hyperpolarization activated cyclic 0.0032 0.0031 0.0196
Entamoeba histolytica acetyltransferase, GNAT family 0.004 0.0045 0.0597
Loa Loa (eye worm) hypothetical protein 0.0022 0.0011 0.0012
Echinococcus multilocularis histone deacetylase 8 0.01 0.0161 0.016
Mycobacterium ulcerans acyl-CoA synthetase 0.0022 0.0011 0.0018
Plasmodium vivax AP endonuclease (DNA-[apurinic or apyrimidinic site] lyase), putative 0.0038 0.0042 0.0839
Schistosoma mansoni ap endonuclease 0.0038 0.0042 0.0277
Brugia malayi Patched family protein 0.0019 0.0006 0.0007
Schistosoma mansoni inositol 145-trisphosphate receptor 0.0023 0.0013 0.0085
Schistosoma mansoni thyroid hormone receptor 0.0043 0.0051 0.0337
Loa Loa (eye worm) voltage-gated potassium channel 0.0023 0.0013 0.0014
Echinococcus multilocularis Lysosomal Pro X carboxypeptidase 0.004 0.0045 0.0043
Trichomonas vaginalis alpha-galactosidase/alpha-N-acetylgalactosaminidase, putative 0.0076 0.0115 0.1823
Plasmodium vivax ataxin-2 like protein, putative 0.0026 0.0019 0.0361
Brugia malayi Serine protease Z688.6 precursor 0.004 0.0045 0.0048
Loa Loa (eye worm) hypothetical protein 0.0019 0.0006 0.0007
Echinococcus multilocularis nuclear receptor subfamily 1 group D 0.0023 0.0012 0.001
Brugia malayi ecdysone receptor 0.002 0.0008 0.0008
Loa Loa (eye worm) hypothetical protein 0.0322 0.0586 0.0622
Schistosoma mansoni hypothetical protein 0.0021 0.0009 0.0061
Echinococcus granulosus fetal alzheimer antigen falz 0.0028 0.0022 0.0138
Echinococcus multilocularis COUP TF:Svp nuclear hormone receptor 0.0043 0.0051 0.0049
Schistosoma mansoni voltage-gated potassium channel 0.0023 0.0013 0.0085
Echinococcus multilocularis aldehyde dehydrogenase, mitochondrial 0.0073 0.011 0.0108
Leishmania major pyruvate kinase 0.0036 0.0039 0.0039
Mycobacterium tuberculosis Probable peptide synthetase Nrp (peptide synthase) 0.0022 0.0011 0.0019
Loa Loa (eye worm) hypothetical protein 0.0019 0.0006 0.0007
Echinococcus granulosus expressed protein 0.0018 0.0003 0.0009
Echinococcus multilocularis musashi 0.003 0.0027 0.0025
Trichomonas vaginalis glucosylceramidase, putative 0.0185 0.0324 0.521
Schistosoma mansoni P2X receptor subunit 0.0072 0.0106 0.0707
Mycobacterium ulcerans bacterioferritin BfrB 0.0018 0.0003 0.0002
Brugia malayi Voltage-gated potassium channel, Shaw-family (KCNC, Kv3-like) alpha-subunit. C. elegans egl-36 ortholog 0.0023 0.0013 0.0014
Schistosoma mansoni transient receptor potential cation channel subfamily m member 0.0023 0.0013 0.0085
Echinococcus multilocularis Alpha N acetylgalactosaminidase 0.0115 0.0189 0.0187
Brugia malayi AMP-binding enzyme family protein 0.0075 0.0113 0.012
Trichomonas vaginalis glucosylceramidase, putative 0.0282 0.051 0.823
Mycobacterium leprae Probable pyruvate kinase PykA 0.0036 0.0039 0.0073
Brugia malayi Serine protease Z688.6 precursor 0.004 0.0045 0.0048
Loa Loa (eye worm) isocitrate dehydrogenase 0.0017 0.0002 0.0002
Plasmodium falciparum AP endonuclease (DNA-[apurinic or apyrimidinic site] lyase), putative 0.0038 0.0042 0.0839
Schistosoma mansoni ferritin 0.0018 0.0003 0.002
Schistosoma mansoni acetyl-CoA synthetase 0.0022 0.0011 0.0074
Trypanosoma brucei pyruvate kinase 1, putative 0.0036 0.0039 0.0039
Schistosoma mansoni high voltage-activated calcium channel Cav2A 0.0023 0.0013 0.0085
Loa Loa (eye worm) hypothetical protein 0.004 0.0045 0.0048
Brugia malayi Patched family protein 0.0019 0.0006 0.0007
Schistosoma mansoni family S9 non-peptidase homologue (S09 family) 0.0069 0.0102 0.0677
Toxoplasma gondii 3'5'-cyclic nucleotide phosphodiesterase domain-containing protein 0.0023 0.0013 0.0026
Loa Loa (eye worm) patched family protein 0.0019 0.0006 0.0007
Echinococcus granulosus histone deacetylase 8 0.01 0.0161 0.1065
Echinococcus granulosus Potassium voltage gated channel protein Shaw 0.0023 0.0013 0.0074
Brugia malayi Cation transporter family protein 0.0081 0.0125 0.0132
Brugia malayi AMP-binding enzyme family protein 0.0022 0.0011 0.0012
Trichomonas vaginalis histone deacetylase 1, 2 ,3, putative 0.0263 0.0473 0.7629
Trypanosoma cruzi pyruvate kinase 2, putative 0.0036 0.0039 0.0039
Brugia malayi nuclear receptor NHR-88 0.002 0.0008 0.0008
Echinococcus granulosus nuclear receptor 2DBD gamma 0.0043 0.0051 0.0327
Loa Loa (eye worm) hypothetical protein 0.0019 0.0006 0.0007
Echinococcus granulosus protein C ets 2 0.0021 0.0009 0.0049
Echinococcus granulosus histone deacetylase 0.0183 0.0319 0.2119
Loa Loa (eye worm) intermediate filament protein 0.003 0.0027 0.0029
Loa Loa (eye worm) hypothetical protein 0.0022 0.0011 0.0012
Trichomonas vaginalis penicillin-binding protein, putative 0.018 0.0314 0.505
Plasmodium vivax pyruvate kinase, putative 0.0036 0.0039 0.0781
Mycobacterium tuberculosis Pantoate--beta-alanine ligase PanC (pantothenate synthetase) (pantoate activating enzyme) 0.2573 0.4901 1
Plasmodium falciparum histone deacetylase 2 0.0183 0.0319 0.6733
Schistosoma mansoni hyperpolarization activated cyclic nucleotide-gated potassium channel 0.0032 0.0031 0.0207
Echinococcus granulosus aldehyde dehydrogenase mitochondrial 0.0073 0.011 0.0719
Plasmodium vivax pyruvate kinase 2, putative 0.0019 0.0005 0.0059
Brugia malayi nuclear receptor RXR 0.002 0.0008 0.0008
Loa Loa (eye worm) histone deacetylase 11 0.01 0.0161 0.0171
Echinococcus granulosus beta LACTamase domain containing family member 0.018 0.0314 0.2086
Mycobacterium tuberculosis Bifunctional enzyme MbtA: salicyl-AMP ligase (SAL-AMP ligase) + salicyl-S-ArCP synthetase 0.0022 0.0011 0.0019
Brugia malayi Iron-sulfur cluster assembly accessory protein 0.0156 0.0268 0.0285
Brugia malayi Patched family protein 0.0019 0.0006 0.0007
Schistosoma mansoni voltage-gated potassium channel 0.0023 0.0013 0.0085
Schistosoma mansoni hypothetical protein 0.0021 0.0009 0.006
Loa Loa (eye worm) hypothetical protein 0.0019 0.0006 0.0007
Giardia lamblia Thymus-specific serine protease precursor 0.004 0.0045 0.086
Trichomonas vaginalis alpha-glucosidase, putative 0.0028 0.0023 0.0321
Schistosoma mansoni patched 1 0.0137 0.0232 0.1549
Trypanosoma cruzi acetyl-CoA synthetase, putative 0.0022 0.0011 0.001
Echinococcus granulosus NADP dependent isocitrate dehydrogenase 0.0017 0.0002 0.0003
Brugia malayi tailless protein 0.002 0.0008 0.0008
Loa Loa (eye worm) voltage and ligand gated potassium channel 0.0091 0.0143 0.0152
Brugia malayi RNA binding protein 0.0063 0.009 0.0096
Echinococcus granulosus voltage gated potassium channel 0.0039 0.0044 0.0282
Trichomonas vaginalis phosphofructokinase, putative 0.0126 0.021 0.336
Schistosoma mansoni hypothetical protein 0.0149 0.0255 0.1696
Echinococcus granulosus Alpha N acetylgalactosaminidase 0.0115 0.0189 0.1246
Brugia malayi Patched family protein 0.0019 0.0006 0.0007
Toxoplasma gondii aldehyde dehydrogenase 0.0073 0.011 0.0223
Loa Loa (eye worm) O-glycosyl hydrolase family 30 protein 0.0282 0.051 0.0542
Loa Loa (eye worm) hypothetical protein 0.0023 0.0013 0.0014
Schistosoma mansoni hypothetical protein 0.0149 0.0255 0.1696
Trypanosoma brucei glucosidase, putative 0.0075 0.0113 0.0118
Schistosoma mansoni voltage-gated potassium channel 0.0023 0.0013 0.0085
Loa Loa (eye worm) patched family protein 0.0019 0.0006 0.0007
Echinococcus multilocularis cyclic nucleotide gated cation channel alpha 3 0.0032 0.0031 0.0029
Echinococcus multilocularis Nuclear hormone receptor HR96 0.002 0.0008 0.0006
Loa Loa (eye worm) hypothetical protein 0.0023 0.0013 0.0014
Loa Loa (eye worm) intermediate filament tail domain-containing protein 0.003 0.0027 0.0029
Echinococcus granulosus ewsr:fli fusion protein type 0.0021 0.0009 0.0049
Echinococcus granulosus potassium:sodium hyperpolarization activated 0.0032 0.0031 0.0196
Brugia malayi hypothetical protein 0.0023 0.0012 0.0013
Toxoplasma gondii pyruvate kinase PyKII 0.0019 0.0005 0.001
Plasmodium falciparum acetyl-CoA synthetase, putative 0.0022 0.0011 0.0193
Echinococcus granulosus short transient receptor potential channel 6 0.0023 0.0013 0.0074
Trichomonas vaginalis voltage and ligand gated potassium channel, putative 0.0032 0.0031 0.0457
Echinococcus multilocularis ETS transcription factor Elf 2 0.0021 0.0009 0.0007
Brugia malayi Ets-domain containing protein 0.0021 0.0009 0.001
Loa Loa (eye worm) histone methyltransferase 0.0027 0.002 0.0022
Trichomonas vaginalis chromodomain-helicase-DNA-binding protein, putative 0.002 0.0007 0.0058
Schistosoma mansoni ferritin light chain 0.0018 0.0003 0.002
Mycobacterium tuberculosis Probable bacterioferritin BfrA 0.0018 0.0003 0.0002
Loa Loa (eye worm) nuclear hormone receptor family member nhr-40 0.0043 0.0051 0.0054
Trypanosoma cruzi acetyl-CoA synthetase, putative 0.0022 0.0011 0.001
Trypanosoma brucei histone deacetylase 2 0.01 0.0161 0.0169
Trichomonas vaginalis D-aminoacylase, putative 0.018 0.0314 0.505
Schistosoma mansoni kinase 0.0051 0.0066 0.0442
Echinococcus multilocularis ETS domain containing protein Elk 1 0.0021 0.0009 0.0007
Brugia malayi Nuclear hormone receptor family member nhr-19 0.0043 0.0051 0.0054
Toxoplasma gondii glycosyl hydrolase, family 31 protein 0.0075 0.0113 0.0231
Echinococcus granulosus potassium channel KvQLT family member kqt 1 0.0023 0.0013 0.0074
Loa Loa (eye worm) nuclear hormone receptor family member nhr-49 0.0043 0.0051 0.0054
Schistosoma mansoni high voltage-activated calcium channel Cav1 0.0023 0.0013 0.0085
Onchocerca volvulus 0.0081 0.0125 0.2099
Echinococcus multilocularis potassium voltage gated channel subfamily H 0.0039 0.0044 0.0042
Echinococcus granulosus ETS transcription factor Elf 2 0.0021 0.0009 0.0049
Toxoplasma gondii phosphofructokinase PFKII 0.0034 0.0034 0.007
Mycobacterium tuberculosis Probable conserved lipoprotein 0.018 0.0314 0.0637
Trichomonas vaginalis penicillin-binding protein, putative 0.018 0.0314 0.505
Brugia malayi RNA recognition motif domain containing protein 0.0063 0.009 0.0096
Mycobacterium tuberculosis Probable fatty-acid-CoA ligase FadD2 (fatty-acid-CoA synthetase) (fatty-acid-CoA synthase) 0.0075 0.0113 0.0226
Echinococcus multilocularis nuclear receptor 2DBD gamma 0.0043 0.0051 0.0049
Schistosoma mansoni coup transcription factor 0.0043 0.0051 0.0337
Loa Loa (eye worm) hypothetical protein 0.002 0.0008 0.0008
Brugia malayi Melibiase family protein 0.0076 0.0115 0.0123
Brugia malayi Carboxylesterase family protein 0.0069 0.0102 0.0108
Schistosoma mansoni transient receptor potential cation channel subfamily m member 0.0023 0.0013 0.0085
Schistosoma mansoni nuclear hormone receptor 0.0043 0.0051 0.0337
Toxoplasma gondii histone deacetylase HDAC4 0.01 0.0161 0.0329
Schistosoma mansoni hyperpolarization activated cyclic nucleotide-gated potassium channel 0.0023 0.0013 0.0085
Brugia malayi Patched family protein 0.0019 0.0006 0.0007
Loa Loa (eye worm) hypothetical protein 0.002 0.0008 0.0008
Leishmania major ATP-dependent phosphofructokinase 0.0126 0.021 0.0221
Echinococcus granulosus potassium voltage gated channel protein 0.0023 0.0013 0.0074
Mycobacterium leprae conserved hypothetical protein 0.018 0.0314 0.0636
Schistosoma mansoni microtubule-associated protein tau 0.0737 0.1382 0.9213
Schistosoma mansoni vesicular amine transporter 0.0023 0.0013 0.0085
Echinococcus multilocularis protein C ets 2 0.0021 0.0009 0.0007
Loa Loa (eye worm) hypothetical protein 0.002 0.0008 0.0008
Echinococcus multilocularis potassium voltage gated channel subfamily D 0.0023 0.0013 0.0011
Echinococcus granulosus guanine nucleotide binding protein Gs subunit 0.0195 0.0342 0.2273
Loa Loa (eye worm) hypothetical protein 0.0019 0.0006 0.0007
Entamoeba histolytica serine carboxypeptidase (S28) family protein 0.004 0.0045 0.0594
Echinococcus multilocularis Nuclear hormone receptor family member nhr 41 0.0043 0.0051 0.0049
Schistosoma mansoni methyl-cpg binding protein mbd 0.0017 0.0002 0.0014
Schistosoma mansoni nuclear receptor nhr-48 0.002 0.0008 0.005
Schistosoma mansoni pyruvate kinase 0.0036 0.0039 0.0259
Echinococcus multilocularis fetal alzheimer antigen, falz 0.0028 0.0022 0.0021
Brugia malayi Smad1 0.0017 0.0002 0.0002
Mycobacterium ulcerans long-chain-fatty-acid-CoA ligase 0.0075 0.0113 0.0226
Trichomonas vaginalis phosphofructokinase, putative 0.0126 0.021 0.336
Echinococcus multilocularis cadherin EGF LAG seven pass G type receptor 0.0149 0.0255 0.0253
Echinococcus multilocularis potassium voltage gated channel subfamily C 0.0023 0.0013 0.0011
Loa Loa (eye worm) TK/EPH protein kinase 0.0071 0.0104 0.0111
Echinococcus multilocularis beta LACTamase domain containing family member 0.018 0.0314 0.0313
Brugia malayi histone deacetylase 11 0.01 0.0161 0.0171
Trypanosoma brucei C-8 sterol isomerase, putative 0.4928 0.9414 1
Brugia malayi PHD-finger family protein 0.0034 0.0034 0.0036
Schistosoma mansoni nuclear receptor 2DBD-gamma 0.0043 0.0051 0.0337
Mycobacterium tuberculosis Peptide synthetase MbtF (peptide synthase) 0.0022 0.0011 0.0019
Loa Loa (eye worm) hypothetical protein 0.0023 0.0013 0.0014
Echinococcus granulosus zinc finger protein 0.0028 0.0024 0.0146
Brugia malayi serine/threonine-protein kinase plk-2 0.01 0.0161 0.0171
Plasmodium vivax histone acetyltransferase GCN5, putative 0.0046 0.0057 0.1163
Echinococcus granulosus survival motor neuron protein 1 0.0766 0.1437 0.9577
Giardia lamblia Pyruvate kinase 0.0036 0.0039 0.0727
Loa Loa (eye worm) hypothetical protein 0.0019 0.0006 0.0007
Echinococcus multilocularis calcium activated potassium channel 0.0023 0.0013 0.0012
Echinococcus multilocularis ETS transcription factor Elf 5 0.0021 0.0009 0.0007
Mycobacterium tuberculosis Probable fatty-acid-CoA ligase FadD35 (fatty-acid-CoA synthetase) (fatty-acid-CoA synthase) 0.0053 0.0071 0.014
Loa Loa (eye worm) hypothetical protein 0.002 0.0008 0.0008
Echinococcus granulosus voltage dependent L type calcium channel subunit|voltage dependent calcium channel 0.0023 0.0013 0.0074
Echinococcus multilocularis protein patched 0.0137 0.0232 0.0231
Plasmodium vivax histone deacetylase 2, putative 0.0183 0.0319 0.6733
Trichomonas vaginalis alpha-glucosidase, putative 0.0075 0.0113 0.179
Loa Loa (eye worm) hypothetical protein 0.018 0.0314 0.0334
Brugia malayi Patched family protein 0.0019 0.0006 0.0007
Loa Loa (eye worm) bromodomain containing protein 0.0022 0.001 0.0011
Schistosoma mansoni gabp alpha 0.0144 0.0245 0.1633
Echinococcus granulosus histone deacetylase 6 0.0183 0.0319 0.2119
Brugia malayi AMP-binding enzyme family protein 0.0022 0.0011 0.0012
Echinococcus multilocularis transient receptor potential gamma protein 0.0023 0.0013 0.0011
Loa Loa (eye worm) hypothetical protein 0.4928 0.9414 1
Echinococcus granulosus voltage gated sodium channel Nav1 alpha subunit 0.0023 0.0013 0.0074
Brugia malayi MH1 domain containing protein 0.0017 0.0002 0.0002
Loa Loa (eye worm) nuclear Hormone Receptor family member 0.0043 0.0051 0.0054
Brugia malayi Voltage-gated potassium channel, Shab-family (KCNB, Kv2-like) alpha-subunit 0.0023 0.0013 0.0014
Echinococcus multilocularis short transient receptor potential channel 6 0.0023 0.0013 0.0011
Echinococcus multilocularis ewsr:fli fusion protein type 0.0021 0.0009 0.0007
Trichomonas vaginalis glucosylceramidase, putative 0.0185 0.0324 0.521
Onchocerca volvulus 0.0314 0.057 1
Loa Loa (eye worm) hypothetical protein 0.0123 0.0205 0.0218
Loa Loa (eye worm) hypothetical protein 0.0023 0.0013 0.0014
Brugia malayi orphan nuclear receptor NR2E1 0.002 0.0008 0.0008
Echinococcus granulosus transient receptor potential cation channel 0.0023 0.0013 0.0074
Echinococcus granulosus potassium voltage gated channel subfamily D 0.0023 0.0013 0.0074
Mycobacterium tuberculosis Probable fatty-acid-CoA ligase FadD5 (fatty-acid-CoA synthetase) (fatty-acid-CoA synthase) 0.0053 0.0071 0.014
Schistosoma mansoni tar DNA-binding protein 0.0063 0.009 0.0601
Echinococcus multilocularis guanine nucleotide binding protein G(s) subunit 0.0195 0.0342 0.0341
Brugia malayi Patched family protein 0.0019 0.0006 0.0007
Onchocerca volvulus 0.0075 0.0113 0.1889
Echinococcus granulosus microtubule associated protein 2 0.0737 0.1382 0.9212
Schistosoma mansoni methyl-cpg binding protein mbd 0.0017 0.0002 0.0014
Echinococcus granulosus pyruvate kinase 0.0036 0.0039 0.0248
Brugia malayi Nuclear hormone receptor family member nhr-3 0.0043 0.0051 0.0054
Echinococcus granulosus intermediate filament protein 0.003 0.0027 0.0167
Mycobacterium ulcerans bacterioferritin BfrA 0.0018 0.0003 0.0002
Trichomonas vaginalis neutral alpha-glucosidase ab precursor, putative 0.0028 0.0023 0.0321
Mycobacterium ulcerans acyl-CoA synthetase 0.0075 0.0113 0.0226
Loa Loa (eye worm) hypothetical protein 0.0076 0.0115 0.0123
Echinococcus multilocularis potassium voltage gated channel subfamily H 0.0091 0.0143 0.0141
Brugia malayi Nuclear hormone receptor-like 1 0.0023 0.0012 0.0013
Toxoplasma gondii pantoate-beta-alanine ligase 0.2573 0.4901 1
Toxoplasma gondii melibiase subfamily protein 0.0115 0.0189 0.0384
Leishmania major apurinic/apyrimidinic endonuclease-redox protein 0.0038 0.0042 0.0042
Trypanosoma cruzi apurinic/apyrimidinic endonuclease 0.0038 0.0042 0.0042
Loa Loa (eye worm) hypothetical protein 0.0081 0.0125 0.0132
Loa Loa (eye worm) hypothetical protein 0.018 0.0314 0.0334
Trichomonas vaginalis conserved hypothetical protein 0.002 0.0007 0.0058
Loa Loa (eye worm) voltage-gated potassium channel 0.0023 0.0013 0.0014
Loa Loa (eye worm) hypothetical protein 0.003 0.0026 0.0027
Loa Loa (eye worm) hypothetical protein 0.0043 0.0051 0.0054
Echinococcus granulosus voltage dependent calcium channel type d subunit|voltage dependent calcium channel|voltage dependent L type calcium channel subu 0.0023 0.0013 0.0074
Schistosoma mansoni hypothetical protein 0.0799 0.15 1
Trichomonas vaginalis prolylcarboxypeptidase, putative 0.004 0.0045 0.0684
Onchocerca volvulus Glucosylceramidase homolog 0.0185 0.0324 0.5637
Brugia malayi Patched family protein 0.0019 0.0006 0.0007
Loa Loa (eye worm) hypothetical protein 0.0019 0.0006 0.0007
Loa Loa (eye worm) histone deacetylase 3 0.0263 0.0473 0.0503
Schistosoma mansoni apoferritin-2 0.0018 0.0003 0.002
Trichomonas vaginalis Clan SC, family S28, unassigned serine peptidase 0.004 0.0045 0.0684
Mycobacterium leprae PROBABLE FATTY-ACID-CoA LIGASE FADD2 (FATTY-ACID-CoA SYNTHETASE) (FATTY-ACID-CoA SYNTHASE) 0.0075 0.0113 0.0224
Brugia malayi Patched related family protein 10 0.0019 0.0006 0.0007
Loa Loa (eye worm) nuclear hormone receptor 0.002 0.0008 0.0008
Echinococcus multilocularis potassium voltage gated channel protein 0.0023 0.0013 0.0011
Brugia malayi protein C24B5.3 0.0019 0.0006 0.0007
Mycobacterium tuberculosis Probable medium chain fatty-acid-CoA ligase FadD14 (fatty-acid-CoA synthetase) (fatty-acid-CoA synthase) 0.0022 0.0011 0.0019
Leishmania major hypothetical protein, conserved 0.0023 0.0013 0.0011
Loa Loa (eye worm) hypothetical protein 0.002 0.0008 0.0008
Mycobacterium tuberculosis Fatty-acid-AMP ligase FadD30 (fatty-acid-AMP synthetase) (fatty-acid-AMP synthase) 0.0056 0.0076 0.0152
Plasmodium falciparum ataxin-2 like protein, putative 0.0026 0.0019 0.0361
Trichomonas vaginalis glucosylceramidase, putative 0.0185 0.0324 0.521
Loa Loa (eye worm) MH1 domain-containing protein 0.0017 0.0002 0.0002
Echinococcus granulosus cyclic nucleotide gated cation channel alpha 3 0.0032 0.0031 0.0196
Echinococcus granulosus acetylcholinesterase 0.0069 0.0102 0.0666
Echinococcus granulosus sodium leak channel non selective protein 0.0023 0.0013 0.0074
Toxoplasma gondii patched family protein 0.0019 0.0006 0.0013
Leishmania major hypothetical protein, conserved 0.0026 0.0019 0.0018
Echinococcus granulosus potassium voltage gated channel protein 0.0023 0.0013 0.0074
Trypanosoma brucei inositol 1,4,5-trisphosphate receptor 0.0023 0.0013 0.0011
Leishmania major histone deacetylase, putative 0.0263 0.0473 0.0501
Echinococcus granulosus potassium voltage gated channel subfamily D 0.0023 0.0013 0.0074
Toxoplasma gondii patched family protein 0.0019 0.0006 0.0013
Echinococcus granulosus GA binding protein alpha chain 0.0144 0.0245 0.1624
Echinococcus multilocularis sodium leak channel non selective protein 0.0023 0.0013 0.0011
Onchocerca volvulus Nuclear receptor subfamily 6 group A member 1 homolog 0.002 0.0008 0.0023
Echinococcus multilocularis Niemann Pick C1 protein 0.0458 0.0846 0.0845
Loa Loa (eye worm) nuclear hormone receptor family member nhr-41 0.0043 0.0051 0.0054
Onchocerca volvulus Pyruvate kinase homolog 0.0036 0.0039 0.058
Loa Loa (eye worm) RNA binding protein 0.0063 0.009 0.0096
Loa Loa (eye worm) hypothetical protein 0.0019 0.0006 0.0007
Loa Loa (eye worm) hypothetical protein 0.0026 0.0019 0.002
Trichomonas vaginalis phosphofructokinase, putative 0.0034 0.0034 0.0505
Loa Loa (eye worm) patched family protein 0.0019 0.0006 0.0007
Loa Loa (eye worm) hypothetical protein 0.002 0.0008 0.0008
Echinococcus granulosus shaker cognate 0.0023 0.0013 0.0074
Mycobacterium ulcerans aldehyde dehydrogenase 0.0073 0.011 0.0219
Toxoplasma gondii pyruvate kinase PyK1 0.0036 0.0039 0.0079
Echinococcus multilocularis geminin 0.0537 0.0997 0.0996
Brugia malayi Nuclear hormone receptor-like 1 0.0043 0.0051 0.0054
Trypanosoma brucei ATP-dependent 6-phosphofructokinase, glycosomal 0.0126 0.021 0.0221
Trypanosoma cruzi ATP-dependent 6-phosphofructokinase, glycosomal 0.0126 0.021 0.0221
Mycobacterium ulcerans acetyl-CoA synthetase 0.0022 0.0011 0.0018
Echinococcus granulosus voltage dependent calcium channel 0.0023 0.0013 0.0074
Trichomonas vaginalis D-aminoacylase, putative 0.018 0.0314 0.505
Echinococcus multilocularis ephrin type A receptor 4 A 0.0069 0.0101 0.0099
Loa Loa (eye worm) hypothetical protein 0.0019 0.0006 0.0007
Schistosoma mansoni histone-lysine n-methyltransferase setb1 0.0019 0.0006 0.0039
Loa Loa (eye worm) hypothetical protein 0.0028 0.0023 0.0024
Plasmodium falciparum pyruvate kinase 2 0.0019 0.0005 0.0059
Schistosoma mansoni tar DNA-binding protein 0.0063 0.009 0.0601
Trichomonas vaginalis voltage and ligand gated potassium channel, putative 0.0068 0.0099 0.1556
Mycobacterium ulcerans peptide synthetase Nrp (peptide synthase) 0.0022 0.0011 0.0018
Trichomonas vaginalis glucosylceramidase, putative 0.0195 0.0343 0.5521
Schistosoma mansoni steroid hormone receptor ad4bp 0.0043 0.0051 0.0337
Echinococcus multilocularis short transient receptor potential channel 6 0.0023 0.0013 0.0011
Trypanosoma brucei glycosyl hydrolase-like protein 0.0028 0.0023 0.0022
Brugia malayi Voltage-gated calcium channel, T-type, alpha subunit. C. elegans cca-1 ortholog 0.0362 0.0663 0.0704
Leishmania major hypothetical protein, conserved 0.018 0.0314 0.0332
Loa Loa (eye worm) hypothetical protein 0.0043 0.0051 0.0054
Brugia malayi CXXC zinc finger family protein 0.0087 0.0135 0.0143
Brugia malayi Glycosyl hydrolases family 31 protein 0.0075 0.0113 0.012
Brugia malayi hypothetical protein 0.0023 0.0012 0.0013
Brugia malayi Patched family protein 0.0019 0.0006 0.0007
Trichomonas vaginalis conserved hypothetical protein 0.0137 0.0232 0.3723
Schistosoma mansoni voltage-gated potassium channel 0.0032 0.0031 0.0207
Schistosoma mansoni P2X receptor subunit 0.0072 0.0106 0.0707
Brugia malayi Voltage-gated potassium channel, Shab-family (KCNB, Kv2-like) alpha-subunit. C. elegans exp-2 ortholog 0.0023 0.0013 0.0014
Brugia malayi hypothetical protein 0.009 0.0141 0.015
Echinococcus multilocularis voltage dependent calcium channel type d subunit 0.0023 0.0013 0.0011
Mycobacterium ulcerans hypothetical protein 0.018 0.0314 0.0637
Schistosoma mansoni histone deacetylase hda2 0.01 0.0161 0.1075
Schistosoma mansoni histone deacetylase 0.0263 0.0473 0.3153
Loa Loa (eye worm) MH2 domain-containing protein 0.0251 0.0449 0.0477
Entamoeba histolytica Niemann-Pick C1 protein, putative 0.032 0.0583 1
Toxoplasma gondii histone deacetylase HDAC3 0.0263 0.0473 0.0965
Toxoplasma gondii 3'5'-cyclic nucleotide phosphodiesterase domain-containing protein 0.0023 0.0013 0.0026
Toxoplasma gondii transporter, cation channel family protein 0.0023 0.0013 0.0026
Echinococcus multilocularis transient receptor potential cation channel 0.0023 0.0013 0.0011
Leishmania major 4-coumarate:coa ligase-like protein 0.0075 0.0113 0.0118
Brugia malayi ERG2 and Sigma1 receptor like protein 0.4928 0.9414 1
Echinococcus granulosus Lysosomal Pro X carboxypeptidase 0.004 0.0045 0.029
Toxoplasma gondii serine carboxypeptidase s28 protein 0.004 0.0045 0.0092
Trypanosoma cruzi histone deacetylase 1, putative 0.0263 0.0473 0.0501
Trypanosoma cruzi histone deacetylase, putative 0.01 0.0161 0.0169
Mycobacterium tuberculosis PROBABLE FATTY-ACID-CoA LIGASE FADD18 (FRAGMENT) (FATTY-ACID-CoA SYNTHETASE) (FATTY-ACID-CoA SYNTHASE) 0.0019 0.0005 0.0007
Brugia malayi beta-lactamase 0.018 0.0314 0.0334
Echinococcus multilocularis potassium voltage gated channel subfamily KQT 0.0023 0.0013 0.0011
Trichomonas vaginalis CAMK family protein kinase 0.01 0.0161 0.2559
Entamoeba histolytica acyl-CoA synthetase, putative 0.0075 0.0113 0.1776
Schistosoma mansoni FTZ-F1 nuclear receptor-like protein 0.0043 0.0051 0.0337
Echinococcus multilocularis acetyl coenzyme A synthetase, cytoplasmic 0.0022 0.0011 0.0009
Echinococcus granulosus 6 phosphofructokinase 0.0126 0.021 0.139
Plasmodium vivax 6-phosphofructokinase, putative 0.0034 0.0034 0.068
Brugia malayi Ets-domain containing protein 0.0144 0.0245 0.026
Trichomonas vaginalis phosphofructokinase, putative 0.0034 0.0034 0.0505
Onchocerca volvulus 0.018 0.0314 0.5462
Entamoeba histolytica hypothetical protein 0.019 0.0334 0.5645
Echinococcus multilocularis neutral alpha glucosidase AB 0.0075 0.0113 0.0112
Echinococcus granulosus nuclear receptor 2DBD gamma 0.0043 0.0051 0.0327
Echinococcus multilocularis expressed conserved protein 0.0301 0.0546 0.0544
Brugia malayi intermediate filament protein 0.003 0.0027 0.0029
Leishmania major histone deacetylase, putative 0.0263 0.0473 0.0501
Echinococcus multilocularis potassium voltage gated channel protein 0.0023 0.0013 0.0011
Onchocerca volvulus Serine\/threonine kinase homolog 0.01 0.0161 0.274
Onchocerca volvulus Pyruvate kinase homolog 0.0036 0.0039 0.058
Entamoeba histolytica glycosyl hydrolase, family 31 protein 0.0075 0.0113 0.1786
Leishmania major 4-coumarate:coa ligase-like protein 0.0075 0.0113 0.0118
Trypanosoma cruzi polo-like protein kinase, putative 0.01 0.0161 0.0169
Echinococcus granulosus Nuclear hormone receptor HR96 0.002 0.0008 0.0039
Brugia malayi acetyltransferase, GNAT family protein 0.015 0.0257 0.0273
Loa Loa (eye worm) hypothetical protein 0.0019 0.0006 0.0007
Brugia malayi MH2 domain containing protein 0.0017 0.0002 0.0002
Echinococcus multilocularis histone lysine methyltransferase setb histone lysine methyltransferase eggless 0.0019 0.0006 0.0004
Echinococcus multilocularis pyruvate kinase 0.0019 0.0005 0.0003
Echinococcus granulosus Protein patched homolog 1 0.0137 0.0232 0.154
Echinococcus granulosus geminin 0.0537 0.0997 0.6644
Loa Loa (eye worm) histone deacetylase 1 0.0263 0.0473 0.0503
Echinococcus multilocularis transient receptor potential cation channel 0.0023 0.0013 0.0011
Echinococcus multilocularis potassium voltage gated channel protein 0.0023 0.0013 0.0011
Echinococcus granulosus voltage gated hydrogen channel 1 0.0023 0.0013 0.0074
Echinococcus granulosus nuclear receptor 2DBD gamma 0.002 0.0008 0.0039
Brugia malayi Intermediate filament tail domain containing protein 0.003 0.0027 0.0029
Echinococcus multilocularis pyruvate kinase 0.0036 0.0039 0.0037
Loa Loa (eye worm) hypothetical protein 0.0023 0.0013 0.0014
Trichomonas vaginalis conserved hypothetical protein 0.002 0.0007 0.0058
Brugia malayi hypothetical protein 0.002 0.0008 0.0008
Echinococcus multilocularis transient receptor potential cation channel 0.0023 0.0013 0.0011
Schistosoma mansoni histone deacetylase 4 5 0.0183 0.0319 0.2128
Brugia malayi AMP-binding enzyme family protein 0.0075 0.0113 0.012
Loa Loa (eye worm) hypothetical protein 0.0019 0.0006 0.0007
Leishmania major hypothetical protein, unknown function 0.0023 0.0013 0.0011
Brugia malayi photoreceptor-specific nuclear receptor 0.0043 0.0051 0.0054
Loa Loa (eye worm) hypothetical protein 0.0039 0.0044 0.0047
Schistosoma mansoni hypothetical protein 0.0149 0.0255 0.1696
Trichomonas vaginalis voltage and ligand gated potassium channel, putative 0.0032 0.0031 0.0457
Onchocerca volvulus 0.0081 0.0125 0.2099
Schistosoma mansoni thyroid hormone receptor 0.0043 0.0051 0.0337
Echinococcus multilocularis potassium:sodium hyperpolarization activated 0.0032 0.0031 0.0029
Mycobacterium tuberculosis Probable esterase/lipase LipP 0.018 0.0314 0.0637
Loa Loa (eye worm) hypothetical protein 0.0019 0.0006 0.0006
Mycobacterium ulcerans acyl-CoA synthetase 0.0022 0.0011 0.0018
Schistosoma mansoni voltage-gated potassium channel 0.0023 0.0013 0.0085
Echinococcus granulosus histone deacetylase 6 0.0183 0.0319 0.2119
Schistosoma mansoni smad1 5 8 and 0.0017 0.0002 0.0011
Plasmodium falciparum ATP-dependent 6-phosphofructokinase 0.0034 0.0034 0.068
Echinococcus multilocularis microtubule associated protein 2 0.0737 0.1382 0.1381
Echinococcus multilocularis p2X purinoceptor 4 0.0072 0.0106 0.0104
Echinococcus multilocularis lamin dm0 0.003 0.0027 0.0025
Loa Loa (eye worm) ets-domain-containing protein 0.0021 0.0009 0.001
Schistosoma mansoni survival motor neuron protein 0.0156 0.0268 0.1789
Mycobacterium ulcerans bifunctional enzyme MbtA: salicyl-AMP ligase (SAL-AMP ligase) + salicyl-S-ACP synthetase 0.0022 0.0011 0.0018
Mycobacterium ulcerans short chain dehydrogenase 0.0019 0.0005 0.0006
Brugia malayi histone deacetylase 3 (HD3) 0.0263 0.0473 0.0503
Loa Loa (eye worm) hypothetical protein 0.002 0.0008 0.0008
Loa Loa (eye worm) hypothetical protein 0.009 0.0141 0.015
Schistosoma mansoni voltage-gated potassium channel 0.003 0.0026 0.017
Echinococcus granulosus nuclear receptor nhr 48 0.002 0.0008 0.0039
Brugia malayi Patched family protein 0.0019 0.0006 0.0007
Echinococcus granulosus histone lysine N methyltransferase MLL3 0.0021 0.001 0.0057
Echinococcus granulosus ecdysone induced protein 78C 0.0043 0.0051 0.0327
Echinococcus multilocularis ETS transcription factor Elf 1 0.0021 0.0009 0.0007
Echinococcus granulosus ephrin type A receptor 4 A 0.0069 0.0101 0.0659
Echinococcus multilocularis ecdysone induced protein 78C 0.0043 0.0051 0.0049
Echinococcus granulosus ryanodine receptor 44f 0.0023 0.0013 0.0074
Schistosoma mansoni hypothetical protein 0.0023 0.0013 0.0085
Giardia lamblia Histone acetyltransferase GCN5 0.004 0.0045 0.0864
Loa Loa (eye worm) D-ets-4 DNA binding domain-containing protein 0.0021 0.0009 0.001
Echinococcus multilocularis cpg binding protein 0.0093 0.0148 0.0146
Trichomonas vaginalis Clan SC, family S28, unassigned serine peptidase 0.004 0.0045 0.0684
Loa Loa (eye worm) GTP-binding regulatory protein Gs alpha-S chain 0.0195 0.0342 0.0364
Brugia malayi acetyl-Coenzyme A synthetase 2 0.0022 0.0011 0.0012
Echinococcus granulosus retinoic acid receptor rxr beta a 0.0043 0.0051 0.0327
Loa Loa (eye worm) PHD-finger family protein 0.0021 0.0009 0.001
Echinococcus multilocularis transfer RNA-Gly 0.0023 0.0013 0.0011
Echinococcus multilocularis histone lysine N methyltransferase MLL3 0.0021 0.001 0.0008
Mycobacterium tuberculosis Probable lipase LipD 0.018 0.0314 0.0637
Echinococcus granulosus ETS transcription factor Elf 5 0.0021 0.0009 0.0049
Mycobacterium tuberculosis Probable 6-phosphofructokinase PfkA (phosphohexokinase) (phosphofructokinase) 0.0126 0.021 0.0425
Loa Loa (eye worm) hypothetical protein 0.018 0.0314 0.0334
Loa Loa (eye worm) hypothetical protein 0.0137 0.0232 0.0247
Brugia malayi nuclear hormone receptor family member nhr-6 0.002 0.0008 0.0008
Trichomonas vaginalis neutral alpha-glucosidase ab precursor, putative 0.0075 0.0113 0.179
Schistosoma mansoni cyclic-nucleotide-gated cation channel 0.0032 0.0031 0.0207
Echinococcus granulosus cadherin EGF LAG seven pass G type receptor 0.0149 0.0255 0.1687
Brugia malayi cation channel family protein 0.0023 0.0013 0.0014
Mycobacterium ulcerans long-chain-fatty-acid--CoA ligase 0.0075 0.0113 0.0226
Echinococcus granulosus Nuclear hormone receptor family member nhr 41 0.0043 0.0051 0.0327
Echinococcus granulosus TRP transient receptor potential channel 0.0023 0.0013 0.0074
Brugia malayi Calcitonin receptor-like protein seb-1 0.0471 0.0871 0.0926
Echinococcus multilocularis pyruvate kinase 0.0029 0.0024 0.0022
Mycobacterium ulcerans esterase/lipase LipP 0.018 0.0314 0.0637
Brugia malayi phosphofructokinase 0.0126 0.021 0.0223
Mycobacterium tuberculosis Bacterioferritin BfrB 0.0018 0.0003 0.0002
Schistosoma mansoni tar DNA-binding protein 0.0063 0.009 0.0601
Trichomonas vaginalis Clan SC, family S28, unassigned serine peptidase 0.004 0.0045 0.0684
Loa Loa (eye worm) histone deacetylase 7A 0.0183 0.0319 0.0339
Loa Loa (eye worm) hypothetical protein 0.0056 0.0076 0.0081
Brugia malayi ecdysteroid receptor 0.0043 0.0051 0.0054
Trypanosoma cruzi histone deacetylase, putative 0.0183 0.0319 0.0337
Echinococcus multilocularis nuclear receptor nhr 48 0.002 0.0008 0.0006
Schistosoma mansoni alpha glucosidase 0.0075 0.0113 0.0755
Schistosoma mansoni voltage-gated potassium channel 0.0023 0.0013 0.0085
Trichomonas vaginalis conserved hypothetical protein 0.002 0.0007 0.0058
Brugia malayi Patched family protein 0.0019 0.0006 0.0007
Loa Loa (eye worm) pigment dispersing factor receptor c 0.0471 0.0871 0.0926
Loa Loa (eye worm) hypothetical protein 0.0168 0.0292 0.031
Mycobacterium ulcerans acyl-CoA synthetase 0.0022 0.0011 0.0018
Loa Loa (eye worm) hypothetical protein 0.0019 0.0006 0.0007
Trichomonas vaginalis chromodomain helicase DNA binding protein, putative 0.002 0.0007 0.0058
Schistosoma mansoni cyclic-nucleotide-gated cation channel 0.0032 0.0031 0.0207
Loa Loa (eye worm) hypothetical protein 0.0043 0.0051 0.0054
Brugia malayi ephrin receptor 1 precursor 0.0026 0.002 0.0021
Loa Loa (eye worm) phosphofructokinase 0.0126 0.021 0.0223
Mycobacterium tuberculosis P-hydroxybenzoyl-AMP ligase FadD22 0.0022 0.0011 0.0019
Trichomonas vaginalis histone deacetylase, putative 0.0263 0.0473 0.7629
Schistosoma mansoni photoreceptor-specific nuclear receptor related 0.0043 0.0051 0.0337
Echinococcus multilocularis potassium voltage gated channel protein 0.0023 0.0013 0.0011
Brugia malayi AMP-binding enzyme family protein 0.0022 0.0011 0.0012
Echinococcus multilocularis acetylcholinesterase 0.0069 0.0102 0.01
Schistosoma mansoni lysosomal Pro-Xaa carboxypeptidase (S28 family) 0.004 0.0045 0.0301
Toxoplasma gondii propionate-CoA ligase 0.0022 0.0011 0.0023
Brugia malayi Patched family protein 0.0019 0.0006 0.0007
Giardia lamblia Endonuclease/Exonuclease/phosphatase 0.0038 0.0042 0.0785
Echinococcus multilocularis FTZ F1 nuclear receptor protein 0.0043 0.0051 0.0049
Trichomonas vaginalis esterase, putative 0.018 0.0314 0.505
Echinococcus granulosus Lysosomal Pro X carboxypeptidase 0.074 0.1387 0.924
Brugia malayi Histone deacetylase family protein 0.0183 0.0319 0.0339
Loa Loa (eye worm) oxidoreductase 0.0022 0.0011 0.0012
Plasmodium vivax histone deacetylase 1, putative 0.0263 0.0473 1
Trypanosoma cruzi histone deacetylase, putative 0.0183 0.0319 0.0337
Trichomonas vaginalis conserved hypothetical protein 0.002 0.0007 0.0058
Trichomonas vaginalis 6-phosphofructokinase, putative 0.0034 0.0034 0.0505
Echinococcus multilocularis gcn5proteinral control of amino acid synthesis 0.015 0.0257 0.0255
Schistosoma mansoni nuclear hormone receptor superfamily protein-related 0.002 0.0008 0.005
Loa Loa (eye worm) ryanodine receptor 0.0023 0.0013 0.0014
Loa Loa (eye worm) hypothetical protein 0.018 0.0314 0.0334
Loa Loa (eye worm) hypothetical protein 0.0043 0.0051 0.0054
Trichomonas vaginalis bromodomain-containing protein, putative 0.0046 0.0057 0.0874
Loa Loa (eye worm) exodeoxyribonuclease III family protein 0.0038 0.0042 0.0044
Schistosoma mansoni hypothetical protein 0.0537 0.0997 0.6647
Brugia malayi Niemann-Pick C1 protein precursor 0.032 0.0583 0.0619
Trypanosoma cruzi long-chain-fatty-acid-CoA ligase, putative 0.0022 0.0011 0.001
Trypanosoma brucei histone deacetylase 3 0.0183 0.0319 0.0337
Echinococcus granulosus methyl CpG binding domain protein 2 0.0017 0.0002 0.0003
Toxoplasma gondii isocitrate dehydrogenase 0.0017 0.0002 0.0004
Echinococcus granulosus lamin dm0 0.003 0.0027 0.0167
Schistosoma mansoni hyperpolarization activated cyclic nucleotide-gated potassium channel 0.0032 0.0031 0.0207
Trichomonas vaginalis glucosylceramidase, putative 0.0185 0.0324 0.521
Echinococcus multilocularis acetylcholinesterase 0.0069 0.0102 0.01
Mycobacterium tuberculosis Probable exodeoxyribonuclease III protein XthA (exonuclease III) (EXO III) (AP endonuclease VI) 0.0038 0.0042 0.0081
Onchocerca volvulus 0.018 0.0314 0.5462
Loa Loa (eye worm) DR-78 0.002 0.0008 0.0008
Loa Loa (eye worm) hypothetical protein 0.032 0.0583 0.0619
Trichomonas vaginalis Clan SC, family S28, unassigned serine peptidase 0.004 0.0045 0.0684
Schistosoma mansoni ferritin 0.0018 0.0003 0.002
Loa Loa (eye worm) hypothetical protein 0.0023 0.0012 0.0013
Echinococcus multilocularis Niemann Pick C1 protein 0.032 0.0583 0.0581
Echinococcus granulosus ETS transcription factor Elf 1 0.0021 0.0009 0.0049
Brugia malayi Patched family protein 0.0019 0.0006 0.0007
Echinococcus multilocularis GA binding protein alpha chain 0.0144 0.0245 0.0243
Echinococcus granulosus voltage gated potassium channel 0.0023 0.0013 0.0074
Echinococcus multilocularis ferritin 0.0018 0.0003 0.0001
Brugia malayi AMP-binding enzyme family protein 0.0075 0.0113 0.012
Schistosoma mansoni nAChR subunit (ShAR1-beta-like) 0.0081 0.0125 0.083
Toxoplasma gondii hypothetical protein 0.0023 0.0013 0.0026
Trypanosoma cruzi C-8 sterol isomerase, putative 0.4928 0.9414 1
Trichomonas vaginalis Clan SC, family S28, unassigned serine peptidase 0.004 0.0045 0.0684
Plasmodium vivax acyl-CoA synthetase, putative 0.0056 0.0076 0.1577
Echinococcus granulosus Niemann Pick C1 protein 0.0458 0.0846 0.5636
Leishmania major histone deacetylase, putative 0.0183 0.0319 0.0337
Onchocerca volvulus 0.0027 0.002 0.0247
Trypanosoma brucei histone deacetylase, putative 0.0183 0.0319 0.0337
Loa Loa (eye worm) hypothetical protein 0.0043 0.0051 0.0054
Echinococcus granulosus two pore calcium channel protein 2 0.0023 0.0013 0.0074
Loa Loa (eye worm) beta-lactamase 0.018 0.0314 0.0334
Toxoplasma gondii histone deacetylase HDAC2 0.0263 0.0473 0.0965
Onchocerca volvulus Uncharacterized family 31 glucosidase KIAA1161 homolog 0.0028 0.0023 0.0293
Echinococcus multilocularis p2X purinoceptor 4 0.0072 0.0106 0.0104
Schistosoma mansoni smad1 5 8 and 0.0017 0.0002 0.0011
Mycobacterium ulcerans non-ribosomal peptide synthetase MbtE 0.0022 0.0011 0.0018
Brugia malayi CHE-14 protein 0.0137 0.0232 0.0247
Onchocerca volvulus 0.0022 0.0011 0.0088
Schistosoma mansoni niemann-pick C1 (NPC1) 0.0325 0.0592 0.3948
Brugia malayi Ryanodine Receptor TM 4-6 family protein 0.0023 0.0013 0.0014
Schistosoma mansoni lamin 0.003 0.0027 0.0178
Brugia malayi histone deacetylase 1 (HD1) 0.0263 0.0473 0.0503
Loa Loa (eye worm) voltage-gated calcium channel 0.0023 0.0013 0.0014
Mycobacterium ulcerans acyl-CoA synthetase 0.0022 0.0011 0.0018
Trichomonas vaginalis glucosylceramidase, putative 0.0282 0.051 0.823
Echinococcus granulosus histone lysine methyltransferase setb 0.0019 0.0006 0.0028
Loa Loa (eye worm) hypothetical protein 0.0069 0.0102 0.0108
Loa Loa (eye worm) 6-phosphofructokinase 0.0126 0.021 0.0223
Loa Loa (eye worm) hypothetical protein 0.0263 0.0473 0.0503
Echinococcus granulosus nuclear receptor subfamily 1 group D 0.0023 0.0012 0.007
Echinococcus multilocularis methyl CpG binding domain protein 2 0.0017 0.0002 0.0001
Echinococcus granulosus potassium voltage gated channel protein 0.0023 0.0013 0.0074
Echinococcus multilocularis mixed lineage leukemia protein mll 0.0021 0.001 0.0008
Brugia malayi oxidoreductase, short chain dehydrogenase/reductase family protein 0.0022 0.0011 0.0012
Schistosoma mansoni P2X receptor subunit 0.0072 0.0106 0.0707
Loa Loa (eye worm) transcription factor SMAD2 0.0251 0.0449 0.0477
Echinococcus granulosus tar DNA binding protein 0.0063 0.009 0.0591
Mycobacterium tuberculosis Probable esterase LipL 0.018 0.0314 0.0637
Schistosoma mansoni apoferritin-2 0.0018 0.0003 0.002
Trichomonas vaginalis sucrase-isomaltase, putative 0.0075 0.0113 0.179
Brugia malayi Voltage-gated potassium channel, Shaw-family (KCNC, Kv3-like) alpha-subunit 0.0023 0.0013 0.0014
Brugia malayi hypothetical protein 0.0023 0.0013 0.0014
Mycobacterium leprae POSSIBLE O-SUCCINYLBENZOIC ACID--CoA LIGASE MENE (OSB-CoA SYNTHETASE) (O-SUCCINYLBENZOATE-CoA SYNTHASE) 0.0022 0.0011 0.0017
Loa Loa (eye worm) steroid hormone receptor 0.0043 0.0051 0.0054
Schistosoma mansoni ecdysone-induced protein 78c (dr-78) 0.0023 0.0012 0.0081
Trichomonas vaginalis Clan SC, family S28, unassigned serine peptidase 0.004 0.0045 0.0684
Loa Loa (eye worm) 6-phosphofructokinase 0.0126 0.021 0.0223
Loa Loa (eye worm) hypothetical protein 0.0019 0.0006 0.0007
Echinococcus granulosus cpg binding protein 0.0093 0.0148 0.0976
Leishmania major aldehyde dehydrogenase, mitochondrial precursor 0.0073 0.011 0.0114
Schistosoma mansoni cyclic-nucleotide-gated cation channel 0.0032 0.0031 0.0207
Loa Loa (eye worm) hypothetical protein 0.0019 0.0006 0.0007
Echinococcus multilocularis ETS transcription factor Elf 2 0.0021 0.0009 0.0007
Echinococcus multilocularis serine:threonine protein kinase PLK1 0.01 0.0161 0.0159
Mycobacterium tuberculosis Possible conserved lipoprotein LpqK 0.018 0.0314 0.0637
Loa Loa (eye worm) RNA recognition domain-containing protein domain-containing protein 0.0063 0.009 0.0096
Loa Loa (eye worm) hypothetical protein 0.0021 0.0009 0.001
Schistosoma mansoni alpha-glucosidase 0.0292 0.0529 0.3524
Brugia malayi Transient-receptor-potential like protein 0.0023 0.0013 0.0014
Brugia malayi Patched related family protein 4 0.0019 0.0006 0.0007
Mycobacterium ulcerans acyl-CoA synthetase 0.0022 0.0011 0.0018
Mycobacterium tuberculosis Possible short-chain dehydrogenase EphD 0.0019 0.0005 0.0007
Mycobacterium ulcerans 6-phosphofructokinase 0.0126 0.021 0.0424
Treponema pallidum diphosphate--fructose-6-phosphate 1-phosphotransferase 0.0126 0.021 1
Echinococcus multilocularis voltage gated potassium channel 0.0039 0.0044 0.0042
Schistosoma mansoni histone deacetylase 4 5 0.0183 0.0319 0.2128
Trichomonas vaginalis maltase-glucoamylase, putative 0.0075 0.0113 0.179
Onchocerca volvulus 0.002 0.0008 0.0023
Mycobacterium ulcerans long-chain-acyl-CoA synthetase 0.0022 0.0011 0.0018
Echinococcus granulosus p2X purinoceptor 4 0.0072 0.0106 0.0697
Mycobacterium tuberculosis Probable pyruvate kinase PykA 0.0036 0.0039 0.0075
Trypanosoma cruzi hypothetical protein, conserved 0.018 0.0314 0.0332
Plasmodium falciparum acyl-CoA synthetase 0.0056 0.0076 0.1577
Toxoplasma gondii AMP-binding enzyme domain-containing protein 0.0022 0.0011 0.0023
Loa Loa (eye worm) nuclear hormone receptor-like 1 0.0023 0.0012 0.0013
Trichomonas vaginalis chromodomain helicase DNA binding protein, putative 0.002 0.0007 0.0058
Loa Loa (eye worm) hypothetical protein 0.0081 0.0124 0.0132
Schistosoma mansoni zinc finger protein 0.002 0.0008 0.005
Schistosoma mansoni voltage-gated potassium channel 0.0023 0.0013 0.0085
Brugia malayi Patched related family protein 12 0.0019 0.0006 0.0007
Trichomonas vaginalis cat eye syndrome critical region protein 2, cscr2, putative 0.0046 0.0057 0.0874
Schistosoma mansoni mixed-lineage leukemia protein mll 0.0021 0.001 0.0068
Echinococcus multilocularis histone deacetylase 6 0.0183 0.0319 0.0318
Echinococcus granulosus thyroid hormone receptor alpha 0.002 0.0008 0.0039
Trichomonas vaginalis CAMK family protein kinase 0.01 0.0161 0.2559
Mycobacterium tuberculosis Conserved protein 0.018 0.0314 0.0637
Echinococcus multilocularis dnaJ subfamily B 0.0799 0.15 0.1499
Brugia malayi Nuclear hormone receptor family member nhr-19 0.0043 0.0051 0.0054
Echinococcus multilocularis nuclear receptor subfamily 4 group A 0.002 0.0008 0.0006
Echinococcus multilocularis potassium large conductance calcium activated 0.0023 0.0013 0.0011
Echinococcus multilocularis cyclic nucleotide gated cation channel 0.0032 0.0031 0.0029
Trichomonas vaginalis CAMK family protein kinase 0.01 0.0161 0.2559
Onchocerca volvulus 0.0081 0.0125 0.2099
Loa Loa (eye worm) hypothetical protein 0.0075 0.0113 0.012
Echinococcus multilocularis p2X purinoceptor 4 0.0072 0.0106 0.0104
Schistosoma mansoni voltage-gated ion channel 0.0023 0.0013 0.0085
Onchocerca volvulus Protein ultraspiracle homolog 0.0043 0.0051 0.0788
Echinococcus multilocularis survival motor neuron protein 1 0.0766 0.1437 0.1436
Entamoeba histolytica exodeoxyribonuclease III, putative 0.0038 0.0042 0.0532
Mycobacterium ulcerans pantoate--beta-alanine ligase 0.2573 0.4901 1
Echinococcus granulosus nuclear receptor subfamily 4 group A 0.002 0.0008 0.0039
Trichomonas vaginalis CAMK family protein kinase 0.01 0.0161 0.2559
Schistosoma mansoni alpha-galactosidase/alpha-n-acetylgalactosaminidase 0.0115 0.0189 0.1256
Trypanosoma cruzi hypothetical protein, conserved 0.018 0.0314 0.0332
Echinococcus granulosus voltage dependent calcium channel 0.0023 0.0013 0.0074
Loa Loa (eye worm) hypothetical protein 0.0082 0.0127 0.0135
Entamoeba histolytica hypothetical protein 0.019 0.0334 0.5645
Mycobacterium tuberculosis Probable hydrolase 0.018 0.0314 0.0637
Loa Loa (eye worm) glycosyl hydrolase family 31 protein 0.0339 0.0619 0.0658
Loa Loa (eye worm) hypothetical protein 0.0019 0.0006 0.0007
Echinococcus multilocularis histone deacetylase 1 0.0263 0.0473 0.0472
Echinococcus granulosus short transient receptor potential channel 6 0.0023 0.0013 0.0074
Leishmania major protein kinase, putative,polo-like protein kinase, putative 0.01 0.0161 0.0169
Loa Loa (eye worm) calcium channel 0.0023 0.0013 0.0014
Schistosoma mansoni Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) 0.0195 0.0342 0.2282
Loa Loa (eye worm) hypothetical protein 0.0023 0.0013 0.0014
Trypanosoma brucei pyruvate kinase 1 0.0036 0.0039 0.0039
Trichomonas vaginalis chromodomain helicase DNA binding protein, putative 0.002 0.0007 0.0058
Loa Loa (eye worm) hypothetical protein 0.0019 0.0006 0.0007
Trichomonas vaginalis alpha-glucosidase, putative 0.0075 0.0113 0.179
Schistosoma mansoni intermediate filament proteins 0.003 0.0027 0.0178
Schistosoma mansoni ryanodine receptor related 0.0023 0.0013 0.0085
Entamoeba histolytica hypothetical protein 0.019 0.0334 0.5645
Loa Loa (eye worm) beta-LACTamase domain containing family member 0.018 0.0314 0.0334
Brugia malayi hypothetical protein 0.0019 0.0006 0.0007
Chlamydia trachomatis pyruvate kinase 0.0036 0.0039 0.1132
Loa Loa (eye worm) nuclear receptor nhr-7B 0.002 0.0008 0.0008
Trichomonas vaginalis CAMK family protein kinase 0.005 0.0064 0.0988
Loa Loa (eye worm) hypothetical protein 0.0019 0.0006 0.0007
Echinococcus multilocularis shaker cognate 0.0023 0.0013 0.0011
Onchocerca volvulus Nuclear receptor subfamily 6 group A member 1 homolog 0.002 0.0008 0.0023
Loa Loa (eye worm) pyruvate kinase 0.0036 0.0039 0.0041
Loa Loa (eye worm) AMP-binding enzyme family protein 0.0022 0.0011 0.0012
Schistosoma mansoni hepatocyte nuclear factor 4-alpha (hnf-4-alpha) 0.002 0.0008 0.005
Loa Loa (eye worm) hypothetical protein 0.0023 0.0012 0.0013
Loa Loa (eye worm) hypothetical protein 0.0056 0.0076 0.0081
Loa Loa (eye worm) hypothetical protein 0.0025 0.0018 0.0019
Mycobacterium ulcerans long-chain-fatty-acid--CoA ligase 0.0022 0.0011 0.0018
Trypanosoma cruzi pyruvate kinase 2, putative 0.0036 0.0039 0.0039
Loa Loa (eye worm) latrophilin receptor protein 2 0.0149 0.0255 0.027
Trichomonas vaginalis histone deacetylase, putative 0.0263 0.0473 0.7629
Brugia malayi Nuclear hormone receptor-like 1 0.0023 0.0012 0.0013
Brugia malayi isocitrate dehydrogenase 0.0017 0.0002 0.0002
Trichomonas vaginalis alpha-glucosidase, putative 0.0075 0.0113 0.179
Onchocerca volvulus Pyruvate kinase homolog 0.0036 0.0039 0.058
Mycobacterium leprae PROBABLE 6-PHOSPHOFRUCTOKINASE PFKA (PHOSPHOHEXOKINASE) (PHOSPHOFRUCTOKINASE) 0.0126 0.021 0.0423
Brugia malayi hypothetical protein 0.0026 0.0019 0.002
Mycobacterium ulcerans acyl-CoA synthetase 0.0022 0.0011 0.0018
Brugia malayi Histone deacetylase 1 0.0263 0.0473 0.0503
Loa Loa (eye worm) abnormal chemotaxis protein 14 0.0137 0.0232 0.0247
Echinococcus granulosus calcium activated potassium channel 0.0023 0.0013 0.0078
Loa Loa (eye worm) hypothetical protein 0.002 0.0008 0.0008
Echinococcus granulosus hyperpolarization activated cyclic 0.0032 0.0031 0.0196
Echinococcus multilocularis carboxylesterase 5A 0.0069 0.0102 0.01
Loa Loa (eye worm) hypothetical protein 0.0045 0.0055 0.0059
Echinococcus multilocularis expressed protein 0.0018 0.0003 0.0001
Mycobacterium tuberculosis Probable fatty-acid-CoA ligase FadD8 (fatty-acid-CoA synthetase) (fatty-acid-CoA synthase) 0.0022 0.0011 0.0019
Trichomonas vaginalis alpha-glucosidase, putative 0.0075 0.0113 0.179
Schistosoma mansoni transient receptor potential channel 4 0.0023 0.0013 0.0085
Schistosoma mansoni alpha-galactosidase/alpha-n-acetylgalactosaminidase 0.0076 0.0115 0.0768
Brugia malayi Large-conductance calcium-activated potassium channel Slo-1 (KCNMA) alpha subunit. C. elegans slo-1 ortholog 0.0023 0.0013 0.0014
Loa Loa (eye worm) hypothetical protein 0.0039 0.0044 0.0047
Schistosoma mansoni nuclear receptor 0.002 0.0008 0.005
Schistosoma mansoni cpg binding protein 0.0093 0.0148 0.0986
Echinococcus multilocularis voltage gated potassium channel 0.0023 0.0013 0.0011
Schistosoma mansoni transient receptor potential channel 0.0023 0.0013 0.0085
Echinococcus granulosus COUP TF:Svp nuclear hormone receptor 0.0043 0.0051 0.0327
Schistosoma mansoni ferritin 0.0018 0.0003 0.002
Mycobacterium tuberculosis Probable aldehyde dehydrogenase 0.0073 0.011 0.0219
Loa Loa (eye worm) fli-1 protein 0.0437 0.0807 0.0857
Schistosoma mansoni alpha-galactosidase/alpha-n-acetylgalactosaminidase 0.0115 0.0189 0.1256
Mycobacterium tuberculosis Conserved protein 0.018 0.0314 0.0637
Trichomonas vaginalis antibiotic synthetase, putative 0.0022 0.0011 0.0133
Trichomonas vaginalis histone deacetylase, putative 0.0263 0.0473 0.7629
Mycobacterium ulcerans fatty-acid-CoA ligase 0.0075 0.0113 0.0226
Brugia malayi Voltage-gated potassium channel, EAG (KCNH1)-related. C. elegans egl-2 ortholog 0.0039 0.0044 0.0047
Onchocerca volvulus 0.003 0.0027 0.0365
Loa Loa (eye worm) hypothetical protein 0.0019 0.0006 0.0007
Trichomonas vaginalis conserved hypothetical protein 0.002 0.0007 0.0058
Loa Loa (eye worm) hypothetical protein 0.0023 0.0013 0.0014
Loa Loa (eye worm) CXXC zinc finger family protein 0.0087 0.0135 0.0143
Trichomonas vaginalis phosphofructokinase, putative 0.0034 0.0034 0.0505
Echinococcus multilocularis conserved hypothetical protein 0.0023 0.0013 0.0011
Treponema pallidum exodeoxyribonuclease (exoA) 0.0038 0.0042 0.1867
Mycobacterium ulcerans hypothetical protein 0.0075 0.0113 0.0226
Trichomonas vaginalis ap endonuclease, putative 0.0038 0.0042 0.0627
Brugia malayi hypothetical protein 0.0314 0.057 0.0606
Loa Loa (eye worm) hypothetical protein 0.0019 0.0006 0.0007
Trichomonas vaginalis alpha-glucosidase, putative 0.0028 0.0023 0.0321
Loa Loa (eye worm) nuclear hormone receptor family member nhr-31 0.0043 0.0051 0.0054

Activities

Activity type Activity value Assay description Source Reference
Potency (functional) = 1.5849 um PUBCHEM_BIOASSAY: qHTS Inhibitors of AmpC Beta-Lactamase (assay with detergent). (Class of assay: confirmatory) [Related pubchem assays: 1002 (Confirmation Concentration-Response Assay for Inhibitors of AmpC Beta-Lactamase (assay with detergent)), 585 (Promiscuous and Specific Inhibitors of AmpC Beta-Lactamase (assay without detergent) - a screen old NIH MLSMR collection), 584 (Promiscuous and Specific Inhibitors of AmpC Beta-Lactamase (assay with detergent) - a screen of the old NIH MLSMR collection), 1003 (Confirmation Cuvette-Based Assay for Inhibitors of AmpC Beta-Lactamase (assay with detergent))] ChEMBL. No reference
Potency (functional) 3.1623 uM PubChem BioAssay. qHTS of alpha-syn Inhibitors. (Class of assay: confirmatory) ChEMBL. No reference
Potency (functional) = 5.0119 um PUBCHEM_BIOASSAY: qHTS Assay for Anthrax Lethal Toxin Internalization. (Class of assay: confirmatory) ChEMBL. No reference
Potency (functional) = 11.2202 um PUBCHEM_BIOASSAY: qHTS Assay for Inhibitors of HPGD (15-Hydroxyprostaglandin Dehydrogenase). (Class of assay: confirmatory) [Related pubchem assays: 2429 (Confirmation qHTS Assay for Inhibitors of HPGD (15-Hydroxyprostaglandin Dehydrogenase)), 2407 (Probe Development Summary for Inhibitors of HPGD (15-Hydroxyprostaglandin Dehydrogenase)), 2427 (Thermal Shift Assay for Inhibitors of HPGD (15-Hydroxyprostaglandin Dehydrogenase))] ChEMBL. No reference
Potency (functional) = 15.8489 um PUBCHEM_BIOASSAY: qHTS Assay for Inhibitors of Aldehyde Dehydrogenase 1 (ALDH1A1). (Class of assay: confirmatory) [Related pubchem assays: 1030 (qHTS Validation Assay for Inhibitors of aldehyde dehydrogenase 1 (ALDH1A1))] ChEMBL. No reference
Potency (functional) 18.526 uM PUBCHEM_BIOASSAY: Primary qHTS for delayed death inhibitors of the malarial parasite plastid, 96 hour incubation. (Class of assay: confirmatory) [Related pubchem assays (depositor defined):AID488745, AID488752, AID488774, AID504848, AID504850] ChEMBL. No reference
Potency (binding) = 39.8107 um PUBCHEM_BIOASSAY: qHTS Assay for Identification of Novel General Anesthetics. In this assay, a GABAergic mimetic model system, apoferritin and a profluorescent 1-aminoanthracene ligand (1-AMA), was used to construct a competitive binding assay for identification of novel general anesthetics (Class of assay: confirmatory) [Related pubchem assays: 2385 (Probe Development Summary for Identification of Novel General Anesthetics), 2323 (Validation apoferritin assay run on SigmaAldrich LOPAC1280 collection)] ChEMBL. No reference

Phenotypes

Whole-cell/tissue/organism interactions

Species name Source Reference Is orphan
Plasmodium falciparum ChEMBL23

Many chemical entities in TDR Targets come from high-throughput screenings with whole cells or tissue samples, and not all assayed compounds have been tested against a single a single target protein, probably because they get ruled out during screening process. Even if these compounds may have not been of interest in the original screening, they may come as interesting leads for other screening assays. Furthermore, we may be able to propose drug-target associations using chemical similarities and network patterns.

Annotated phenotypes:

We have no manually annotated phenotypes for this drug. What does this mean? / Care to help?
In TDR Targets, information about phenotypes that are caused by drugs, or by genetic manipulation of cells (e.g. gene knockouts or knockdowns) is manually curated from the literature. These descriptions help to describe the potential of the target for drug development. If no information is available for this gene or if the information is incomplete, this may mean that i) the papers containing this information either appeared after the curation effort for this organism was carried out or they were inadvertently missed by curators; or that ii) the curation effort for this organism has not yet started.
 
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External resources for this compound

Bibliographic References

No literature references available for this target.

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