Detailed information for compound 1343111

Basic information

Technical information
  • Name: Unnamed compound
  • MW: 448.309 | Formula: C24H18BrNO3
  • H donors: 0 H acceptors: 2 LogP: 5.77 Rotable bonds: 6
    Rule of 5 violations (Lipinski): 1
  • SMILES: COc1cccc(c1)c1ncc2c(c1COC(=O)c1cccc(c1)Br)cccc2
  • InChi: 1S/C24H18BrNO3/c1-28-20-10-5-7-16(13-20)23-22(21-11-3-2-6-18(21)14-26-23)15-29-24(27)17-8-4-9-19(25)12-17/h2-14H,15H2,1H3
  • InChiKey: OXZFOVHRUIDZQO-UHFFFAOYSA-N  


Substructure search Similarity search

Network

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Synonyms

No synonyms found for this compound

Targets

Known targets for this compound

Species Target name Source Bibliographic reference
Homo sapiens glucagon-like peptide 1 receptor Starlite/ChEMBL No references
Homo sapiens synuclein, alpha (non A4 component of amyloid precursor) Starlite/ChEMBL No references
Homo sapiens geminin, DNA replication inhibitor Starlite/ChEMBL No references

Predicted pathogen targets for this compound

By orthology
No druggable targets predicted by orthology data
By sequence similarity to non orthologous known druggable targets
Species Potential target Known druggable target Length Alignment span Identity
Brugia malayi Hypothetical 65.5 kDa Trp-Asp repeats containing protein F02E8.5 inchromosome X geminin, DNA replication inhibitor 209 aa 176 aa 27.8 %
Loa Loa (eye worm) pigment dispersing factor receptor c glucagon-like peptide 1 receptor 463 aa 388 aa 25.8 %
Obtained from network model

Ranking Plot

Putative Targets List

Species Potential target Raw Global Species
Brugia malayi Protein kinase domain containing protein 0.035 0.0471 0.0444
Trichomonas vaginalis AGC family protein kinase 0.0202 0.0147 0.0739
Schistosoma mansoni serine/threonine protein kinase 0.0251 0.0255 0.0255
Trichomonas vaginalis AGC family protein kinase 0.0166 0.0068 0.0343
Loa Loa (eye worm) camk/mapkapk/mnk protein kinase 0.089 0.1654 0.1637
Schistosoma mansoni protein kinase 0.028 0.0319 0.0319
Echinococcus granulosus 3'partial|tyrosine protein kinase Fgr 0.0472 0.0738 0.0712
Schistosoma mansoni ephrin receptor 0.0366 0.0507 0.0507
Entamoeba histolytica protein kinase, putative 0.0419 0.0623 0.3127
Schistosoma mansoni protein kinase 0.0807 0.1473 0.1473
Loa Loa (eye worm) TK/EGFR protein kinase 0.173 0.3495 0.3482
Schistosoma mansoni protein kinase 0.0755 0.1359 0.1359
Onchocerca volvulus 0.0209 0.0162 0.0379
Schistosoma mansoni hypothetical protein 0.0233 0.0215 0.0215
Loa Loa (eye worm) hypothetical protein 0.1366 0.2697 0.2682
Loa Loa (eye worm) AGC/RSK/MSK protein kinase 0.0613 0.1048 0.103
Schistosoma mansoni tyrosine kinase 0.1016 0.193 0.193
Schistosoma mansoni tyrosine kinase 0.1138 0.2197 0.2197
Trichomonas vaginalis CMGC family protein kinase 0.0356 0.0486 0.2438
Entamoeba histolytica protein kinase, putative 0.1019 0.1936 0.9713
Loa Loa (eye worm) hypothetical protein 0.0922 0.1725 0.1708
Loa Loa (eye worm) hypothetical protein 0.0315 0.0396 0.0377
Echinococcus granulosus Protein kinase C brain isozyme 0.0879 0.1631 0.1608
Loa Loa (eye worm) CAMK/MLCK protein kinase 0.0248 0.0249 0.0229
Loa Loa (eye worm) hypothetical protein 0.0166 0.0069 0.0049
Echinococcus granulosus serine:threonine protein kinase 0.0487 0.0771 0.0745
Brugia malayi protein-tyrosine kinase 0.0385 0.0549 0.0522
Trichomonas vaginalis AGC family protein kinase 0.0139 0.0011 0.0056
Echinococcus multilocularis serine:threonine protein kinase 0.0487 0.0771 0.0745
Brugia malayi serine/threonine protein kinase 6 0.0475 0.0746 0.072
Schistosoma mansoni serine/threonine-protein kinase 0.0571 0.0957 0.0957
Trichomonas vaginalis CAMK family protein kinase 0.0251 0.0255 0.128
Brugia malayi SH2 domain containing protein 0.0218 0.0183 0.0155
Echinococcus multilocularis calcium:calmodulin dependent protein kinase 0.0202 0.0147 0.0119
Echinococcus multilocularis serine threonine protein kinase nrc serine threonine protein kinase gad 0.0545 0.0899 0.0874
Echinococcus granulosus roundabout 2 0.0378 0.0532 0.0506
Loa Loa (eye worm) TK/FER protein kinase 0.0218 0.0183 0.0163
Loa Loa (eye worm) hypothetical protein 0.0233 0.0215 0.0196
Echinococcus multilocularis serine threonine protein kinase 0.073 0.1304 0.128
Trichomonas vaginalis STE family protein kinase 0.0242 0.0235 0.1177
Toxoplasma gondii calcium-dependent protein kinase CDPK2A 0.028 0.0318 0.1643
Toxoplasma gondii AGC kinase 0.1019 0.1936 1
Plasmodium vivax casein kinase 2, alpha subunit, putative 0.0356 0.0486 0.5404
Leishmania major protein kinase, putative 0.0475 0.0746 0.4135
Trichomonas vaginalis AGC family protein kinase 0.0139 0.0011 0.0056
Trichomonas vaginalis AGC family protein kinase 0.0239 0.0229 0.1147
Echinococcus multilocularis activated cdc42 kinase 1 0.0437 0.0663 0.0637
Trypanosoma cruzi STE/STE20 serine/threonine-protein kinase, putative 0.0248 0.0248 0.1377
Toxoplasma gondii CMGC kinase, MAPK family (ERK) MAPK-1 0.0245 0.0243 0.1253
Trichomonas vaginalis AGC family protein kinase 0.0239 0.0229 0.1147
Echinococcus multilocularis protein kinase c eta type 0.0149 0.0033 0.0005
Echinococcus multilocularis Rac GTPase activating protein 1 0.0149 0.0033 0.0005
Echinococcus granulosus GTPase activating Rap:RanGAP domain 3 0.0233 0.0215 0.0188
Loa Loa (eye worm) CK1/CK1/CK1-D protein kinase 0.028 0.0319 0.03
Loa Loa (eye worm) hypothetical protein 0.0233 0.0215 0.0196
Schistosoma mansoni protein kinase 0.0562 0.0936 0.0936
Schistosoma mansoni tyrosine kinase 0.173 0.3495 0.3495
Echinococcus granulosus fibroblast growth factor receptor 4 0.0686 0.1209 0.1184
Trypanosoma brucei protein kinase, putative 0.0223 0.0193 0.097
Trichomonas vaginalis CMGC family protein kinase 0.0386 0.0552 0.2767
Brugia malayi Sex muscle abnormal protein 5 0.0183 0.0106 0.0078
Trichomonas vaginalis CAMK family protein kinase 0.0251 0.0255 0.128
Loa Loa (eye worm) hypothetical protein 0.1177 0.2283 0.2268
Echinococcus granulosus activated cdc42 kinase 1 0.0437 0.0663 0.0637
Loa Loa (eye worm) hypothetical protein 0.0941 0.1767 0.175
Loa Loa (eye worm) AGC/PKN protein kinase 0.082 0.1502 0.1485
Trichomonas vaginalis AGC family protein kinase 0.0166 0.0068 0.0343
Echinococcus multilocularis dual specificity protein kinase clk2 0.033 0.0428 0.0401
Echinococcus multilocularis serine:threonine protein kinase N2 0.0574 0.0963 0.0938
Loa Loa (eye worm) hypothetical protein 0.0149 0.0033 0.0013
Trypanosoma cruzi Protein kinase B 0.0571 0.0957 0.5304
Trypanosoma cruzi CMGC/DYRK protein kinase, putative 0.0524 0.0854 0.4734
Onchocerca volvulus 0.018 0.0099 0.021
Trichomonas vaginalis CMGC family protein kinase 0.0386 0.0552 0.2767
Trypanosoma cruzi STE/STE20 serine/threonine-protein kinase, putative 0.0248 0.0248 0.1377
Trichomonas vaginalis STE family protein kinase 0.0242 0.0235 0.1177
Trichomonas vaginalis CMGC family protein kinase 0.0356 0.0486 0.2438
Loa Loa (eye worm) TK/KIN16 protein kinase 0.1787 0.3619 0.3606
Loa Loa (eye worm) hypothetical protein 0.0455 0.0702 0.0684
Schistosoma mansoni serine/threonine protein kinase 0.0574 0.0963 0.0963
Brugia malayi hypothetical protein 0.046 0.0713 0.0687
Brugia malayi diacylglycerol kinase 0.0149 0.0033 0.0005
Echinococcus granulosus serine:threonine protein kinase PAK 3 0.0267 0.029 0.0262
Loa Loa (eye worm) AUR protein kinase 0.0475 0.0746 0.0727
Trypanosoma cruzi STE/STE11 serine/threonine-protein kinase, putative 0.0223 0.0193 0.1072
Brugia malayi Protein kinase domain containing protein 0.035 0.0471 0.0444
Loa Loa (eye worm) TK/EPH protein kinase 0.0433 0.0653 0.0634
Loa Loa (eye worm) CAMK/CAMK2 protein kinase 0.028 0.0318 0.0299
Brugia malayi cAMP-dependent protein kinase catalytic subunit, putative 0.0329 0.0426 0.0399
Loa Loa (eye worm) TK/FER protein kinase 0.0218 0.0183 0.0163
Echinococcus granulosus hypothetical protein 0.0229 0.0207 0.018
Echinococcus granulosus neurotracting:lsamp:neurotrimin:obcam 0.0282 0.0324 0.0297
Trichomonas vaginalis AGC family protein kinase 0.0166 0.0068 0.0343
Loa Loa (eye worm) hypothetical protein 0.0243 0.0239 0.0219
Schistosoma mansoni tyrosine kinase 0.1083 0.2077 0.2077
Loa Loa (eye worm) TK/ABL protein kinase 0.0808 0.1476 0.1459
Loa Loa (eye worm) CK1/CK1/CK1-A protein kinase 0.028 0.0319 0.03
Echinococcus granulosus geminin 0.0205 0.0154 0.0126
Loa Loa (eye worm) TK/ALK protein kinase 0.1098 0.211 0.2094
Onchocerca volvulus 0.0218 0.0183 0.0435
Echinococcus multilocularis tyrosine protein kinase Src42A 0.0472 0.0738 0.0712
Schistosoma mansoni serine/threonine protein kinase 0.0245 0.0243 0.0243
Trypanosoma cruzi cAMP-dependent protein kinase catalytic subunit 1 0.0329 0.0426 0.2364
Schistosoma mansoni tyrosine kinase 0.0472 0.0738 0.0738
Brugia malayi Protein kinase domain containing protein 0.0218 0.0183 0.0155
Echinococcus granulosus glycogen synthase kinase 3 beta 0.0419 0.0623 0.0597
Brugia malayi Casein kinase II, alpha chain 0.0356 0.0486 0.0459
Loa Loa (eye worm) TK/FER protein kinase 0.0218 0.0183 0.0163
Echinococcus multilocularis tyrosine protein kinase Btk29A 0.0938 0.1759 0.1735
Leishmania major mitogen-activated protein kinase 3, putative,map kinase 3, putative 0.046 0.0713 0.3951
Echinococcus multilocularis phosphorylase kinase gamma subunit 0.035 0.0471 0.0444
Loa Loa (eye worm) hypothetical protein 0.0286 0.0331 0.0312
Plasmodium falciparum serine/threonine protein kinase 0.0196 0.0135 0.1497
Loa Loa (eye worm) TK protein kinase 0.0385 0.0549 0.053
Schistosoma mansoni serine/threonine protein kinase 0.0196 0.0135 0.0135
Brugia malayi Protein kinase domain containing protein 0.0209 0.0162 0.0135
Entamoeba histolytica protein kinase domain containing protein 0.0201 0.0147 0.0735
Echinococcus granulosus calcium:calmodulin dependent protein kinase type 1 0.028 0.0318 0.0291
Loa Loa (eye worm) TK/FAK protein kinase 0.1094 0.2102 0.2086
Brugia malayi protein unc-22 0.0196 0.0135 0.0107
Brugia malayi Protein kinase domain containing protein 0.0524 0.0854 0.0828
Echinococcus multilocularis tyrosine protein kinase Fyn 0.0472 0.0738 0.0712
Brugia malayi Tyrosine-protein kinase abl-1 0.0365 0.0504 0.0477
Echinococcus multilocularis casein kinase I alpha 0.028 0.0319 0.0292
Echinococcus multilocularis glycogen synthase kinase 3 beta 0.0419 0.0623 0.0597
Echinococcus multilocularis Immunoglobulin 0.023 0.021 0.0182
Brugia malayi Temporarily assigned gene name protein 59 0.0233 0.0215 0.0188
Trichomonas vaginalis AGC family protein kinase 0.1045 0.1994 1
Schistosoma mansoni serine/threonine protein kinase 0.0574 0.0963 0.0963
Echinococcus granulosus tyrosine protein kinase Src64B 0.0472 0.0738 0.0712
Echinococcus granulosus tyrosine protein kinase HCK 0.0289 0.0338 0.0311
Leishmania major casein kinase II, putative 0.0356 0.0486 0.2695
Trichomonas vaginalis CAMK family protein kinase 0.0251 0.0255 0.128
Loa Loa (eye worm) STE/STE20/PAKA protein kinase 0.0162 0.0061 0.0041
Loa Loa (eye worm) TK/FER protein kinase 0.0218 0.0183 0.0163
Trypanosoma cruzi cdc2-related kinase 3 0.0386 0.0552 0.3058
Loa Loa (eye worm) hypothetical protein 0.0149 0.0033 0.0013
Leishmania major glycogen synthase kinase, putative;with=GeneDB:LinJ18_V3.0270 0.0419 0.0623 0.3456
Plasmodium vivax serine/threonine protein kinase 6, putative 0.0475 0.0746 0.8294
Trichomonas vaginalis CAMK family protein kinase 0.0251 0.0255 0.128
Echinococcus granulosus ribosomal protein s6 kinase beta 1 0.0574 0.0963 0.0938
Loa Loa (eye worm) CMGC/SRPK protein kinase 0.0196 0.0135 0.0115
Trichomonas vaginalis CMGC family protein kinase 0.0386 0.0552 0.2767
Trichomonas vaginalis AGC family protein kinase 0.0139 0.0011 0.0056
Loa Loa (eye worm) AGC/PKC/ETA protein kinase 0.0728 0.1301 0.1283
Plasmodium vivax serine/threonine kinase-1, putative 0.033 0.0428 0.4757
Schistosoma mansoni unc-13 (munc13) 0.0154 0.0043 0.0043
Trichomonas vaginalis AGC family protein kinase 0.0475 0.0746 0.3742
Plasmodium vivax glycogen synthase kinase 3, putative 0.0419 0.0623 0.6932
Loa Loa (eye worm) hypothetical protein 0.0792 0.144 0.1422
Entamoeba histolytica PH domain containing protein kinase, putative 0.0355 0.0484 0.2426
Leishmania major serine/threonine-protein kinase, putative,protein kinase, putative 0.0524 0.0854 0.4734
Brugia malayi MAP kinase sur-1 0.0245 0.0243 0.0215
Trypanosoma cruzi casein kinase, putative 0.028 0.0319 0.1771
Trichomonas vaginalis AGC family protein kinase 0.0166 0.0068 0.0343
Trichomonas vaginalis CAMK family protein kinase 0.0251 0.0255 0.128
Brugia malayi Protein kinase domain containing protein 0.0218 0.0183 0.0155
Trichomonas vaginalis CAMK family protein kinase 0.0456 0.0705 0.3536
Echinococcus granulosus tyrosine protein kinase shark 0.0218 0.0183 0.0155
Echinococcus granulosus cGMP dependent protein kinase 0.0294 0.0349 0.0321
Echinococcus granulosus casein kinase I delta 0.028 0.0319 0.0292
Echinococcus multilocularis mitogen activated protein kinase 0.0245 0.0243 0.0215
Echinococcus multilocularis mitogen activated protein kinase kinase kinase 0.0333 0.0436 0.0409
Loa Loa (eye worm) hypothetical protein 0.0151 0.0036 0.0016
Schistosoma mansoni growth factor receptor-bound protein 0.0191 0.0123 0.0123
Loa Loa (eye worm) CMGC/DYRK/DYRK2 protein kinase 0.0201 0.0147 0.0127
Trichomonas vaginalis AGC family protein kinase 0.0202 0.0147 0.0739
Echinococcus granulosus proto oncogene serine:threonine protein kinase 0.0709 0.1258 0.1234
Trichomonas vaginalis CAMK family protein kinase 0.0202 0.0147 0.0739
Trichomonas vaginalis AGC family protein kinase 0.0394 0.0569 0.2856
Echinococcus granulosus dual specificity protein kinase clk2 0.033 0.0428 0.0401
Brugia malayi Protein kinase domain containing protein 0.0577 0.097 0.0944
Entamoeba histolytica protein kinase domain containing protein 0.0475 0.0746 0.3742
Echinococcus multilocularis c src tyrosine kinase 0.0305 0.0373 0.0346
Schistosoma mansoni serine/threonine protein kinase 0.0294 0.0349 0.0349
Echinococcus granulosus cyclin dependent kinase 1 0.0386 0.0552 0.0525
Trypanosoma brucei 5'-AMP-activated protein kinase catalytic subunit alpha, putative 0.0251 0.0255 0.128
Schistosoma mansoni hypothetical protein 0.0368 0.0512 0.0512
Echinococcus multilocularis tyrosine protein kinase Src64B 0.0472 0.0738 0.0712
Entamoeba histolytica protein kinase domain containing protein 0.0223 0.0193 0.097
Trypanosoma cruzi casein kinase, putative 0.028 0.0319 0.1771
Trichomonas vaginalis CMGC family protein kinase 0.0201 0.0147 0.0735
Trichomonas vaginalis AGC family protein kinase 0.0139 0.0011 0.0056
Echinococcus multilocularis mitogen activated protein kinase kinase kinase 0.0301 0.0365 0.0338
Entamoeba histolytica protein kinase domain containing protein 0.0419 0.0623 0.3127
Echinococcus multilocularis geminin 0.0205 0.0154 0.0126
Echinococcus multilocularis protein kinase shaggy 0.0419 0.0623 0.0597
Brugia malayi serine/threonine-protein kinase PAK 7 0.0844 0.1553 0.1529
Plasmodium vivax protein kinase Crk2 0.0386 0.0552 0.6133
Loa Loa (eye worm) AGC/DMPK/ROCK protein kinase 0.2688 0.5592 0.5583
Trichomonas vaginalis AGC family protein kinase 0.0166 0.0068 0.0343
Echinococcus multilocularis calcium:calmodulin dependent protein kinase type 0.028 0.0318 0.0291
Loa Loa (eye worm) hypothetical protein 0.0231 0.0212 0.0192
Echinococcus multilocularis PAK box P21 Rho binding 0.0205 0.0155 0.0127
Brugia malayi Protein kinase domain containing protein 0.1177 0.2283 0.2262
Trichomonas vaginalis CAMK family protein kinase 0.028 0.0318 0.1596
Echinococcus multilocularis N chimaerin 0.0245 0.0243 0.0216
Loa Loa (eye worm) AGC/GRK/GRK protein kinase 0.032 0.0407 0.0388
Echinococcus multilocularis mitogen activated protein kinase 11 0.046 0.0713 0.0686
Plasmodium vivax NIMA-related protein kinase (Pfnek-1), putative 0.0394 0.0569 0.633
Trypanosoma brucei kinetoplastid kinetochore protein 19 0.033 0.0428 0.2146
Leishmania major protein kinase, putative 0.028 0.0318 0.1764
Loa Loa (eye worm) hypothetical protein 0.0876 0.1624 0.1607
Schistosoma mansoni serine/threonine protein kinase 0.028 0.0319 0.0319
Echinococcus granulosus sodium:potassium dependent atpase beta subunit 0.0444 0.0679 0.0653
Brugia malayi protein kinase C3,putative 0.0566 0.0944 0.0919
Brugia malayi Probable G protein-coupled receptor kinase F19C6.1, putative 0.032 0.0407 0.038
Leishmania major serine/threonine-protein kinase, putative,protein kinase, putative 0.0196 0.0135 0.0746
Trypanosoma cruzi CMGC/DYRK protein kinase, putative 0.0524 0.0854 0.4734
Trypanosoma brucei mitogen-activated protein kinase kinase 5 0.0242 0.0235 0.1177
Loa Loa (eye worm) TK/FER protein kinase 0.0218 0.0183 0.0163
Schistosoma mansoni rap gtpase-activating protein 0.0233 0.0215 0.0215
Trypanosoma brucei kinetoplastid kinetochore protein 10 0.033 0.0428 0.2146
Echinococcus granulosus serine:threonine protein kinase 3 0.0738 0.1322 0.1297
Trichomonas vaginalis CAMK family protein kinase 0.0251 0.0255 0.128
Trichomonas vaginalis CMGC family protein kinase 0.0201 0.0147 0.0735
Loa Loa (eye worm) CMGC/CLK protein kinase 0.033 0.0428 0.0409
Schistosoma mansoni tyrosine kinase 0.0686 0.1209 0.1209
Echinococcus multilocularis growth factor receptor bound protein 2 0.0183 0.0106 0.0078
Echinococcus multilocularis tyrosine protein kinase lyn lyn a protein tyrosine kinase lymphocyte specific protein tyrosine kinase 0.0472 0.0738 0.0712
Leishmania major mitogen-activated protein kinase kinase 5, putative;with=GeneDB:LmxM36.0860 0.0242 0.0235 0.13
Trichomonas vaginalis CAMK family protein kinase 0.0202 0.0147 0.0739
Echinococcus multilocularis tyrosine protein kinase 0.0577 0.097 0.0944
Loa Loa (eye worm) hypothetical protein 0.0461 0.0715 0.0696
Onchocerca volvulus 0.0196 0.0135 0.0305
Echinococcus granulosus maternal embryonic leucine zipper kinase 0.0257 0.0268 0.024
Echinococcus multilocularis Ribosomal protein S6 kinase beta 2 0.0574 0.0963 0.0938
Trypanosoma brucei STE/STE11 serine/threonine-protein kinase, putative 0.0223 0.0193 0.097
Trypanosoma brucei Vacuolar sorting protein 39 domain 1/Vacuolar sorting protein 39 domain 2, putative 0.0233 0.0215 0.1081
Schistosoma mansoni defective proboscis extension response (dpr)-related 0.023 0.021 0.021
Toxoplasma gondii calcium-dependent protein kinase CDPK3 0.028 0.0318 0.1643
Trypanosoma cruzi SNF1-related protein kinases, putative 0.0251 0.0255 0.1415
Brugia malayi p21/Cdc42/Rac1-activated kinase 0.0162 0.0061 0.0033
Trichomonas vaginalis CAMK family protein kinase 0.0958 0.1804 0.9048
Schistosoma mansoni serine/threonine protein kinase 0.0423 0.0631 0.0631
Echinococcus granulosus mitogen activated protein kinase 0.0245 0.0243 0.0215
Echinococcus granulosus casein kinase I alpha 0.028 0.0319 0.0292
Trichomonas vaginalis AGC family protein kinase 0.0139 0.0011 0.0056
Loa Loa (eye worm) CAMK/CAMKL/MELK protein kinase 0.0625 0.1074 0.1056
Entamoeba histolytica cell division protein kinase 2, putative 0.0386 0.0552 0.2767
Schistosoma mansoni serine/threonine protein kinase 0.0239 0.0229 0.0229
Trypanosoma cruzi casein kinase II, putative 0.0356 0.0486 0.2695
Echinococcus multilocularis calcium activated potassium channel 0.0469 0.0732 0.0706
Loa Loa (eye worm) hypothetical protein 0.0349 0.0469 0.045
Loa Loa (eye worm) hypothetical protein 0.0349 0.0469 0.045
Echinococcus granulosus RNA directed DNA polymerase 0.0151 0.0036 0.0008
Schistosoma mansoni tyrosine kinase 0.1268 0.2481 0.2481
Onchocerca volvulus 0.1857 0.3772 1
Echinococcus granulosus calcium:calmodulin dependent protein kinase type 0.028 0.0318 0.0291
Echinococcus granulosus nervana 2 0.0444 0.0679 0.0653
Schistosoma mansoni serine/threonine protein kinase 0.0894 0.1664 0.1664
Brugia malayi cell division control protein 2 homolog 0.0386 0.0552 0.0525
Brugia malayi casein kinase I 0.028 0.0319 0.0292
Brugia malayi Protein kinase domain containing protein 0.089 0.1654 0.163
Entamoeba histolytica PH domain containing protein kinase, putative 0.0571 0.0957 0.4798
Echinococcus multilocularis serine:threonine protein kinase 3 0.0738 0.1322 0.1297
Echinococcus multilocularis myosin iiia 0.0248 0.0248 0.0221
Plasmodium falciparum cGMP-dependent protein kinase 0.0294 0.0349 0.3877
Schistosoma mansoni hypothetical protein 0.0368 0.0512 0.0512
Brugia malayi Variant SH3 domain containing protein 0.0183 0.0106 0.0078
Trichomonas vaginalis CAMK family protein kinase 0.0251 0.0255 0.128
Toxoplasma gondii AGC kinase 0.0329 0.0426 0.2202
Echinococcus multilocularis protein KINase family member (kin 25) 0.0243 0.0239 0.0211
Brugia malayi hypothetical protein 0.0218 0.0183 0.0155
Plasmodium falciparum calcium-dependent protein kinase 4 0.028 0.0318 0.3538
Echinococcus granulosus N chimaerin 0.0245 0.0243 0.0216
Trichomonas vaginalis AGC family protein kinase 0.0166 0.0068 0.0343
Trypanosoma cruzi casein kinase, putative 0.028 0.0319 0.1771
Brugia malayi Kinase associated domain 1 family protein 0.0368 0.0512 0.0485
Schistosoma mansoni cell adhesion molecule 0.0317 0.0399 0.0399
Brugia malayi ephrin receptor 1 precursor 0.0237 0.0224 0.0197
Brugia malayi SH2 domain containing protein 0.0218 0.0183 0.0155
Echinococcus multilocularis G protein coupled receptor kinase 6 0.032 0.0407 0.038
Leishmania major protein kinase, putative,SNF1-related protein kinases, putative 0.0251 0.0255 0.1415
Schistosoma mansoni tyrosine kinase 0.1268 0.2481 0.2481
Schistosoma mansoni kinase 0.0921 0.1722 0.1722
Giardia lamblia Kinase, NEK 0.0394 0.0569 0.3156
Schistosoma mansoni serine/threonine protein kinase 0.0386 0.0552 0.0552
Loa Loa (eye worm) hypothetical protein 0.0424 0.0633 0.0614
Brugia malayi Protein kinase domain containing protein 0.1098 0.2111 0.2088
Echinococcus multilocularis serine:threonine kinase SAD 1 0.0251 0.0255 0.0228
Schistosoma mansoni protein kinase 0.0267 0.029 0.029
Giardia lamblia Aurora kinase 0.0475 0.0746 0.4135
Echinococcus granulosus melanoma receptor tyrosine protein kinase 0.1138 0.2197 0.2175
Echinococcus granulosus cAMP dependent protein kinase catalytic subunit 0.0329 0.0426 0.0399
Entamoeba histolytica serine/threonine protein kinase, putative 0.0958 0.1804 0.9048
Trichomonas vaginalis AGC family protein kinase 0.1045 0.1994 1
Trichomonas vaginalis CAMK family protein kinase 0.0202 0.0147 0.0739
Echinococcus multilocularis NCK adaptor protein 0.0191 0.0123 0.0095
Onchocerca volvulus 0.0419 0.0623 0.1608
Echinococcus multilocularis casein kinase i 0.028 0.0319 0.0292
Toxoplasma gondii calcium-dependent protein kinase CDPK2B 0.028 0.0318 0.1643
Brugia malayi Protein kinase domain containing protein 0.2688 0.5592 0.5579
Schistosoma mansoni protein kinase 0.0807 0.1473 0.1473
Schistosoma mansoni protein kinase 0.0665 0.1163 0.1163
Entamoeba histolytica SH2-protein kinase domain containing protein 0.0197 0.0136 0.0684
Brugia malayi bone morphogenetic protein type 1 receptor 0.0258 0.0271 0.0244
Schistosoma mansoni nck2/grb4 0.0183 0.0106 0.0106
Loa Loa (eye worm) CAMK/CAMKL/CHK1 protein kinase 0.074 0.1325 0.1308
Trichomonas vaginalis AGC family protein kinase 0.0166 0.0068 0.0343
Brugia malayi Cam kinase protein 1 0.028 0.0318 0.0291
Plasmodium falciparum protein serine/threonine kinase-1 0.033 0.0428 0.4757
Brugia malayi Serine/threonine-protein kinase SULU 0.046 0.0713 0.0687
Trichomonas vaginalis CAMK family protein kinase 0.0958 0.1804 0.9048
Echinococcus granulosus dual specificity 0.0201 0.0147 0.0119
Entamoeba histolytica protein kinase, putative 0.0245 0.0242 0.1214
Trypanosoma cruzi Vacuolar sorting protein 39 domain 1/Vacuolar sorting protein 39 domain 2, putative 0.0233 0.0215 0.1195
Trichomonas vaginalis AGC family protein kinase 0.0475 0.0746 0.3742
Leishmania major cell division protein kinase 2,cdc2-related kinase 0.0386 0.0552 0.3058
Echinococcus granulosus 3-phosphoinositide-dependent protein kinase 1 0.0239 0.0229 0.0201
Trichomonas vaginalis AGC family protein kinase 0.0139 0.0011 0.0056
Loa Loa (eye worm) hypothetical protein 0.03 0.0363 0.0344
Plasmodium falciparum casein kinase 1 0.028 0.0319 0.3552
Trichomonas vaginalis CMGC family protein kinase 0.0201 0.0147 0.0735
Echinococcus granulosus neuroglian 0.0291 0.0343 0.0316
Toxoplasma gondii aurora kinase 0.0475 0.0746 0.3852
Echinococcus granulosus protein kinase c iota type 0.1039 0.1981 0.1959
Echinococcus multilocularis nervana 2 0.0444 0.0679 0.0653
Echinococcus granulosus cAMP dependent protein kinase catalytic subunit 0.0329 0.0426 0.0399
Echinococcus granulosus casein kinase I delta 0.028 0.0319 0.0292
Loa Loa (eye worm) CMGC/MAPK/ERK1 protein kinase 0.0245 0.0243 0.0223
Trypanosoma cruzi mitogen activated protein kinase 2, putative 0.0245 0.0243 0.1345
Trichomonas vaginalis CAMK family protein kinase 0.0257 0.0268 0.1342
Loa Loa (eye worm) STE/STE20/SLK protein kinase 0.0404 0.0591 0.0572
Echinococcus granulosus tyrosine protein kinase ABL1 0.0808 0.1476 0.1452
Loa Loa (eye worm) CAMK protein kinase 0.0196 0.0135 0.0115
Brugia malayi casein kinase 1, delta 0.028 0.0319 0.0292
Schistosoma mansoni protein kinase 0.0404 0.0591 0.0591
Echinococcus multilocularis guanine nucleotide exchange factor VAV2 0.0245 0.0243 0.0216
Echinococcus granulosus growth factor receptor bound protein 2 0.0191 0.0123 0.0095
Echinococcus granulosus protein tyrosine kinase 0.1083 0.2077 0.2055
Trichomonas vaginalis ribosomal protein S6 kinase, 90kD, polypeptide, putative 0.0166 0.0068 0.0343
Trypanosoma cruzi cAMP-dependent protein kinase catalytic subunit 2 0.0329 0.0426 0.2364
Plasmodium vivax serine/threonine protein kinase KIN, putative 0.0251 0.0255 0.2837
Loa Loa (eye worm) TKL/STKR/TYPE2 protein kinase 0.0217 0.0181 0.0161
Echinococcus granulosus protein kinase 0.0329 0.0426 0.0399
Toxoplasma gondii protein kinase G AGC kinase family member PKG 0.0294 0.0349 0.1801
Echinococcus multilocularis mitogen activated protein kinase 11 0.046 0.0713 0.0686
Schistosoma mansoni tyrosine kinase 0.0226 0.0201 0.0201
Loa Loa (eye worm) CAMK/CAMKL/BRSK protein kinase 0.0251 0.0255 0.0236
Schistosoma mansoni cell adhesion molecule 0.0147 0.0028 0.0028
Loa Loa (eye worm) AGC/GRK/GRK protein kinase 0.0345 0.046 0.0441
Echinococcus multilocularis 3 phosphoinositide dependent protein kinase 1 0.0239 0.0229 0.0201
Loa Loa (eye worm) hypothetical protein 0.0282 0.0324 0.0305
Plasmodium falciparum calcium-dependent protein kinase 5 0.028 0.0318 0.3538
Echinococcus granulosus titin 0.0196 0.0135 0.0107
Entamoeba histolytica protein kinase domain containing protein 0.0356 0.0486 0.2438
Schistosoma mansoni serine/threonine protein kinase 0.0667 0.1167 0.1167
Echinococcus granulosus proto oncogene tyrosine protein kinase LCK 0.0472 0.0738 0.0712
Loa Loa (eye worm) hypothetical protein 0.0329 0.0426 0.0407
Echinococcus multilocularis dual specificity 0.0201 0.0147 0.0119
Echinococcus granulosus tyrosine protein kinase Src42A 0.0271 0.0299 0.0272
Echinococcus granulosus serine:threonine protein kinase N2 0.0246 0.0245 0.0217
Schistosoma mansoni tyrosine kinase 0.1138 0.2197 0.2197
Echinococcus multilocularis tyrosine protein kinase Src42A 0.0271 0.0299 0.0272
Brugia malayi Protein kinase domain containing protein 0.1268 0.2481 0.246
Trichomonas vaginalis CMGC family protein kinase 0.0209 0.0162 0.0814
Echinococcus granulosus ribosomal protein S6 kinase alpha 3 0.0894 0.1664 0.1641
Entamoeba histolytica hypothetical protein 0.0524 0.0854 0.4283
Leishmania major cell division related protein kinase 2,cdc2-related kinase 0.0386 0.0552 0.3058
Loa Loa (eye worm) CDC7 protein kinase 0.0209 0.0162 0.0143
Entamoeba histolytica PH domain containing protein kinase, putative 0.0571 0.0957 0.4798
Loa Loa (eye worm) PLK/PLK1 protein kinase 0.0958 0.1804 0.1787
Echinococcus granulosus expressed protein 0.0196 0.0135 0.0107
Echinococcus granulosus serine:threonine protein kinase PAK 4 0.0739 0.1325 0.13
Trichomonas vaginalis 3-phosphoinositide dependent protein kinase-1, putative 0.0166 0.0068 0.0343
Entamoeba histolytica serine/threonine protein kinase, putative 0.0251 0.0255 0.128
Echinococcus granulosus cyclin dependent kinase 19 0.035 0.0471 0.0444
Trichomonas vaginalis CMGC family protein kinase 0.0209 0.0162 0.0814
Echinococcus multilocularis serine:threonine protein kinase PAK 4 0.0739 0.1325 0.13
Schistosoma mansoni protein kinase 0.0267 0.029 0.029
Schistosoma mansoni serine/threonine protein kinase 0.0855 0.1578 0.1578
Onchocerca volvulus 0.0233 0.0215 0.0521
Trichomonas vaginalis CMGC family protein kinase 0.0245 0.0243 0.1217
Echinococcus granulosus cGMP dependent protein kinase 1 0.0294 0.0349 0.0321
Trichomonas vaginalis AGC family protein kinase 0.0139 0.0011 0.0056
Trichomonas vaginalis CAMK family protein kinase 0.0202 0.0147 0.0739
Toxoplasma gondii AGC kinase 0.0329 0.0426 0.2202
Giardia lamblia Kinase, CMGC CK2 0.0356 0.0486 0.2695
Loa Loa (eye worm) RasGEF domain-containing protein 0.0149 0.0033 0.0013
Trichomonas vaginalis STE family protein kinase 0.0248 0.0248 0.1246
Echinococcus granulosus p21 activated protein kinase 1 Dpak1 0.0267 0.029 0.0262
Trichomonas vaginalis AGC family protein kinase 0.0574 0.0963 0.4831
Brugia malayi Protein kinase c protein 2 0.0406 0.0594 0.0568
Schistosoma mansoni serine/threonine protein kinase 0.0469 0.0732 0.0732
Trichomonas vaginalis CAMK family protein kinase 0.0958 0.1804 0.9048
Brugia malayi RhoGEF domain containing protein 0.0149 0.0033 0.0005
Schistosoma mansoni Neurotrimin precursor (hNT) 0.023 0.021 0.021
Trichomonas vaginalis CAMK family protein kinase 0.0202 0.0147 0.0739
Trichomonas vaginalis AGC family protein kinase 0.0613 0.1048 0.5258
Loa Loa (eye worm) hypothetical protein 0.023 0.021 0.019
Giardia lamblia Kinase, CAMK CAMKL 0.0251 0.0255 0.1415
Schistosoma mansoni protein kinase 0.0807 0.1473 0.1473
Trichomonas vaginalis CAMK family protein kinase 0.0958 0.1804 0.9048
Trypanosoma cruzi cAMP-dependent protein kinase catalytic subunit 3 0.0329 0.0426 0.2364
Trypanosoma cruzi 5'-AMP-activated protein kinase catalytic subunit alpha, putative 0.0251 0.0255 0.1415
Echinococcus multilocularis Glutaredoxin protein 5 0.0444 0.0679 0.0653
Trichomonas vaginalis AGC family protein kinase 0.0166 0.0068 0.0343
Leishmania major protein kinase A catalytic subunit isoform 1 0.0329 0.0426 0.2364
Loa Loa (eye worm) G protein-coupled receptor kinase 1 0.032 0.0407 0.0388
Entamoeba histolytica protein kinase, putative 0.0574 0.0963 0.4831
Onchocerca volvulus Tyrosine kinase homolog 0.1565 0.3134 0.8298
Schistosoma mansoni protein kinase 0.0223 0.0193 0.0193
Echinococcus multilocularis telomerase reverse transcriptase subunit 0.0151 0.0036 0.0008
Schistosoma mansoni serine/threonine protein kinase 0.0329 0.0426 0.0426
Onchocerca volvulus 0.0154 0.0043 0.0062
Echinococcus granulosus c-Jun N-terminal kinases 0.4701 1 1
Echinococcus granulosus cGMP dependent protein kinase 1 0.0294 0.0349 0.0321
Schistosoma mansoni serine/threonine protein kinase 0.0709 0.1258 0.1258
Trichomonas vaginalis CMGC family protein kinase 0.0356 0.0486 0.2438
Echinococcus granulosus mitogen activated protein kinase kinase kinase 0.0755 0.1359 0.1335
Entamoeba histolytica serine/threonine- protein kinase 6 , putative 0.0475 0.0746 0.3742
Leishmania major mitogen activated protein kinase, putative,map kinase, putative 0.0245 0.0243 0.1345
Entamoeba histolytica serine/threonine protein kinase 6, putative 0.0475 0.0746 0.3742
Schistosoma mansoni serine/threonine-protein kinase 0.0571 0.0957 0.0957
Giardia lamblia Kinase, NEK 0.0394 0.0569 0.3156
Plasmodium falciparum tyrosine kinase-like protein, putative 0.0192 0.0126 0.14
Schistosoma mansoni serine/threonine protein kinase 0.0475 0.0746 0.0746
Trypanosoma cruzi rac serine-threonine kinase, putative 0.0545 0.0899 0.4986
Loa Loa (eye worm) immunoglobulin I-set domain-containing protein 0.0147 0.0028 0.0008
Echinococcus multilocularis CDC7 cell division cycle 7 0.0209 0.0162 0.0135
Entamoeba histolytica protein kinase, putative 0.0205 0.0155 0.0776
Trypanosoma cruzi casein kinase, putative 0.028 0.0319 0.1771
Echinococcus multilocularis mitogen activated protein kinase kinase kinase 0.0755 0.1359 0.1335
Schistosoma mansoni protein kinase 0.0242 0.0235 0.0235
Echinococcus multilocularis cyclin dependent kinase 5 0.0386 0.0552 0.0525
Echinococcus multilocularis tyrosine protein kinase Fyn 0.0472 0.0738 0.0712
Brugia malayi putative serine/threonine kinase SADA gamma 0.0251 0.0255 0.0228
Echinococcus multilocularis casein kinase I delta 0.028 0.0319 0.0292
Loa Loa (eye worm) AGC/PDK1 protein kinase 0.0239 0.0229 0.0209
Schistosoma mansoni serine/threonine protein kinase 0.0329 0.0426 0.0426
Trypanosoma brucei SNF1-related protein kinases, putative 0.0251 0.0255 0.128
Echinococcus granulosus NCK adaptor protein 0.0183 0.0106 0.0078
Schistosoma mansoni serine/threonine protein kinase 0.0667 0.1167 0.1167
Giardia lamblia Kinase, CMGC DYRK 0.0201 0.0147 0.0812
Trichomonas vaginalis CAMK family protein kinase 0.0625 0.1074 0.5386
Trichomonas vaginalis AGC family protein kinase 0.0639 0.1105 0.5545
Echinococcus multilocularis cAMP dependent protein kinase catalytic subunit 0.0329 0.0426 0.0399
Loa Loa (eye worm) hypothetical protein 0.0218 0.0183 0.0163
Echinococcus granulosus casein kinase I alpha 0.028 0.0319 0.0292
Schistosoma mansoni vesicular amine transporter 0.023 0.021 0.021
Echinococcus multilocularis 0.0494 0.0788 0.0762
Trichomonas vaginalis CAMK family protein kinase 0.0202 0.0147 0.0739
Echinococcus granulosus c src tyrosine kinase 0.0305 0.0373 0.0346
Trypanosoma brucei serine/arginine-rich protein specific kinase SRPK, putative 0.0196 0.0135 0.0675
Onchocerca volvulus 0.0524 0.0853 0.2221
Loa Loa (eye worm) TK/FER protein kinase 0.0218 0.0183 0.0163
Echinococcus granulosus dual specificity 0.0201 0.0147 0.0119
Echinococcus granulosus epidermal growth factor receptor 0.1138 0.2197 0.2175
Echinococcus granulosus dual specificity 0.0201 0.0147 0.0119
Echinococcus multilocularis STE20 serine:threonine protein kinase 0.0977 0.1844 0.1821
Trypanosoma cruzi mitogen-activated protein kinase 3, putative 0.046 0.0713 0.3951
Schistosoma mansoni serine/threonine protein kinase 0.0728 0.1301 0.1301
Brugia malayi Hr1 repeat family protein 0.082 0.1502 0.1478
Echinococcus multilocularis protein kinase c epsilon type 0.0728 0.1301 0.1276
Trypanosoma cruzi mitogen-activated protein kinase kinase 5 0.0242 0.0235 0.13
Onchocerca volvulus 0.0193 0.0128 0.0289
Trichomonas vaginalis AGC family protein kinase 0.1045 0.1994 1
Trichomonas vaginalis CMGC family protein kinase 0.0356 0.0486 0.2438
Schistosoma mansoni serine/threonine protein kinase 0.0162 0.0061 0.0061
Onchocerca volvulus 0.0498 0.0796 0.2068
Trichomonas vaginalis CAMK family protein kinase 0.0251 0.0255 0.128
Echinococcus granulosus calcium:calmodulin dependent protein kinase I 0.0245 0.0242 0.0214
Entamoeba histolytica PH domain containing protein kinase, putative 0.0355 0.0484 0.2426
Entamoeba histolytica hypothetical protein 0.0149 0.0033 0.0165
Trichomonas vaginalis CAMK family protein kinase 0.0257 0.0268 0.1342
Leishmania major serine/threonine protein kinase, putative,protein kinase, putative 0.0251 0.0255 0.1415
Brugia malayi Variant SH3 domain containing protein 0.0183 0.0106 0.0078
Echinococcus multilocularis Serine:threonine protein kinase PLK4 0.0419 0.0623 0.0597
Echinococcus multilocularis titin 0.0196 0.0135 0.0107
Brugia malayi Variant SH3 domain containing protein 0.0245 0.0243 0.0216
Trichomonas vaginalis AGC family protein kinase 0.0166 0.0068 0.0343
Giardia lamblia Kinase, CAMK CAMKL 0.0251 0.0255 0.1415
Plasmodium vivax calcium-dependent protein kinase, putative 0.028 0.0318 0.3538
Echinococcus multilocularis tyrosine protein kinase Srms 0.0385 0.0549 0.0522
Loa Loa (eye worm) hypothetical protein 0.0498 0.0796 0.0778
Loa Loa (eye worm) STE/STE20/MSN protein kinase 0.0329 0.0426 0.0407
Trichomonas vaginalis CMGC family protein kinase 0.0245 0.0243 0.1217
Brugia malayi Probable G protein-coupled receptor kinase F19C6.1, putative 0.0345 0.046 0.0433
Echinococcus granulosus tyrosine protein kinase transmembrane receptor 0.0183 0.0106 0.0078
Brugia malayi P38 map kinase family protein 2 0.046 0.0713 0.0686
Trichomonas vaginalis serine/threonine-protein kinase, putative 0.0139 0.0011 0.0056
Onchocerca volvulus 0.0832 0.1527 0.4015
Loa Loa (eye worm) RhoGAP domain-containing protein 0.0245 0.0243 0.0224
Trypanosoma cruzi glycogen synthase kinase 3, putative 0.0419 0.0623 0.3456
Loa Loa (eye worm) hypothetical protein 0.028 0.0318 0.0299
Trichomonas vaginalis CAMK family protein kinase 0.0202 0.0147 0.0739
Echinococcus multilocularis dual specificity 0.0524 0.0854 0.0828
Loa Loa (eye worm) hypothetical protein 0.0409 0.0601 0.0582
Loa Loa (eye worm) hypothetical protein 0.0348 0.0467 0.0448
Echinococcus granulosus serine:threonine protein kinase MARK2 0.0855 0.1578 0.1554
Schistosoma mansoni atypical protein kinase C 0.1062 0.2032 0.2032
Brugia malayi Egg laying defective protein 4 0.0294 0.0349 0.0321
Schistosoma mansoni protein kinase 0.0258 0.0271 0.0271
Trichomonas vaginalis AGC family protein kinase 0.1045 0.1994 1
Schistosoma mansoni protein kinase 0.0329 0.0426 0.0426
Trichomonas vaginalis CMGC family protein kinase 0.0356 0.0486 0.2438
Schistosoma mansoni serine/threonine protein kinase 0.0329 0.0426 0.0426
Loa Loa (eye worm) hypothetical protein 0.0524 0.0853 0.0835
Brugia malayi Fes/CIP4 homology domain containing protein 0.0223 0.0194 0.0166
Loa Loa (eye worm) calcium/calmodulin-dependent protein kinase ID 0.028 0.0318 0.0299
Loa Loa (eye worm) hypothetical protein 0.0244 0.0239 0.022
Trichomonas vaginalis CAMK family protein kinase 0.0958 0.1804 0.9048
Schistosoma mansoni protein kinase C mu 0.0149 0.0033 0.0033
Loa Loa (eye worm) hypothetical protein 0.015 0.0035 0.0015
Onchocerca volvulus 0.0244 0.0239 0.0585
Echinococcus granulosus serine:threonine protein kinase TAO1 0.046 0.0713 0.0687
Trypanosoma cruzi casein kinase, delta isoform, putative 0.028 0.0319 0.1771
Loa Loa (eye worm) CAMK/PHK protein kinase 0.035 0.0471 0.0452
Brugia malayi Protein kinase domain containing protein 0.0487 0.0771 0.0745
Echinococcus multilocularis tyrosine protein kinase transmembrane receptor 0.0183 0.0106 0.0078
Echinococcus granulosus protein kinase c eta type 0.0149 0.0033 0.0005
Loa Loa (eye worm) IKK protein kinase 0.1857 0.3772 0.376
Brugia malayi hypothetical protein 0.0265 0.0285 0.0258
Loa Loa (eye worm) AUR protein kinase 0.0475 0.0746 0.0727
Brugia malayi p70 ribosomal S6 kinase beta 0.1019 0.1936 0.1913
Leishmania major mitogen activated protein kinase 4, putative;with=GeneDB:LmxM19.1440 0.0245 0.0243 0.1345
Loa Loa (eye worm) hypothetical protein 0.0147 0.0028 0.0008
Loa Loa (eye worm) AGC/RSK/RSK protein kinase 0.0894 0.1664 0.1648
Echinococcus granulosus phosphorylase kinase gamma subunit 0.035 0.0471 0.0444
Echinococcus multilocularis fibroblast growth factor receptor 4 0.0686 0.1209 0.1184
Trichomonas vaginalis STE family protein kinase 0.0205 0.0155 0.0776
Schistosoma mansoni tyrosine kinase 0.1016 0.193 0.193
Trichomonas vaginalis CMGC family protein kinase 0.0245 0.0243 0.1217
Echinococcus multilocularis C2 calcium dependent membrane targeting 0.0154 0.0043 0.0015
Trichomonas vaginalis AGC family protein kinase 0.0613 0.1048 0.5258
Echinococcus multilocularis insulin receptor 0.1268 0.2481 0.246
Loa Loa (eye worm) TKL/STKR/TYPE1 protein kinase 0.0217 0.0181 0.0161
Trypanosoma cruzi cdc2-related kinase 1 0.0386 0.0552 0.3058
Schistosoma mansoni protein kinase 0.0205 0.0155 0.0155
Loa Loa (eye worm) variant SH3 domain-containing protein 0.0149 0.0033 0.0013
Brugia malayi Protein kinase domain containing protein 0.074 0.1325 0.1301
Loa Loa (eye worm) camk/mapkapk/mapkapk protein kinase 0.1302 0.2558 0.2543
Echinococcus multilocularis serine:threonine protein kinase PAK 3 0.0267 0.029 0.0262
Echinococcus multilocularis basic fibroblast growth factor receptor 1 A 0.0686 0.1209 0.1184
Brugia malayi RhoGAP domain containing protein 0.0149 0.0033 0.0005
Echinococcus granulosus serine:threonine kinase SAD 1 0.0251 0.0255 0.0228
Trichomonas vaginalis CK1 family protein kinase 0.028 0.0319 0.1602
Loa Loa (eye worm) TK/ROR protein kinase 0.0183 0.0106 0.0086
Echinococcus multilocularis calcium:calmodulin dependent protein kinase type 0.028 0.0318 0.0291
Echinococcus multilocularis cAMP dependent protein kinase catalytic subunit 0.0329 0.0426 0.0399
Echinococcus multilocularis casein kinase ii subunit alpha 0.0356 0.0486 0.0459
Loa Loa (eye worm) hypothetical protein 0.0251 0.0255 0.0236
Echinococcus multilocularis protein kinase c iota type 0.1039 0.1981 0.1959
Entamoeba histolytica protein kinase, putative 0.0239 0.0229 0.1147
Brugia malayi SRC-1 0.0472 0.0738 0.0712
Loa Loa (eye worm) hypothetical protein 0.0368 0.0512 0.0493
Echinococcus granulosus CDC7 cell division cycle 7 0.0209 0.0162 0.0135
Echinococcus multilocularis RNA directed DNA polymerase 0.0151 0.0036 0.0008
Echinococcus granulosus cAMP dependent protein kinase catalytic subunit 0.0329 0.0426 0.0399
Loa Loa (eye worm) TK protein kinase 0.0289 0.0338 0.0319
Plasmodium falciparum serine/threonine protein kinase, putative 0.0475 0.0746 0.8294
Loa Loa (eye worm) calcium/calmodulin-dependent protein kinase subunit type II alpha 0.0527 0.086 0.0842
Entamoeba histolytica protein kinase, putative 0.0284 0.0329 0.1649
Entamoeba histolytica protein kinase domain containing protein 0.0423 0.0631 0.3168
Toxoplasma gondii cell-cycle-associated protein kinase CDK, putative 0.0386 0.0552 0.2848
Echinococcus granulosus defective proboscis extension response 0.023 0.021 0.0182
Loa Loa (eye worm) protein kinase domain-containing protein 0.0272 0.0301 0.0282
Toxoplasma gondii cell-cycle-associated protein kinase GSK, putative 0.0419 0.0623 0.322
Echinococcus multilocularis serine:threonine protein kinase PLK1 0.0958 0.1804 0.1781
Leishmania major rac serine-threonine kinase, putative,protein kinase, putative 0.0447 0.0685 0.3796
Plasmodium vivax calcium-dependent protein kinase 3, putative 0.028 0.0318 0.3538
Trypanosoma cruzi kinetoplastid kinetochore protein 19, putative 0.033 0.0428 0.2372
Echinococcus multilocularis tyrosine protein kinase Fyn 0.0385 0.0549 0.0522
Entamoeba histolytica protein kinase, putative 0.0267 0.029 0.1454
Echinococcus granulosus protein kinase c epsilon type 0.0728 0.1301 0.1276
Brugia malayi Immunoglobulin I-set domain containing protein 0.0265 0.0285 0.0258
Trichomonas vaginalis CAMK family protein kinase 0.0958 0.1804 0.9048
Plasmodium falciparum calcium-dependent protein kinase 1 0.028 0.0318 0.3538
Echinococcus granulosus tyrosine protein kinase Fyn 0.0472 0.0738 0.0712
Echinococcus granulosus calcium:calmodulin dependent protein kinase type 0.0807 0.1473 0.1449
Schistosoma mansoni serine/threonine protein kinase 0.0855 0.1578 0.1578
Echinococcus granulosus serine:threonine protein kinase MARK2 0.0855 0.1578 0.1554
Echinococcus multilocularis cAMP dependent protein kinase catalytic subunit 0.0329 0.0426 0.0399
Echinococcus granulosus calcium:calmodulin dependent protein kinase 0.0545 0.0899 0.0874
Trichomonas vaginalis AGC family protein kinase 0.0475 0.0746 0.3742
Brugia malayi Protein kinase domain containing protein 0.0703 0.1245 0.122
Echinococcus granulosus ephrin type A receptor 4 A 0.0366 0.0507 0.048
Loa Loa (eye worm) TK/FER protein kinase 0.0218 0.0183 0.0163
Brugia malayi Protein kinase domain containing protein 0.0218 0.0183 0.0155
Schistosoma mansoni nephrin 0.0325 0.0418 0.0418
Echinococcus granulosus Serine/threonine-protein kinase Genghis Khan 0.0667 0.1167 0.1142
Trypanosoma cruzi mitogen activated protein kinase 4, putative 0.0245 0.0243 0.1345
Trypanosoma brucei STE20-like serine/threonine-protein kinase 1, putative 0.0248 0.0248 0.1246
Echinococcus multilocularis serine:threonine protein kinase 12 B 0.0475 0.0746 0.072
Giardia lamblia Kinase, STE STE20 0.0242 0.0235 0.13
Brugia malayi STE20-like kinase MST 0.0738 0.1322 0.1297
Brugia malayi Immunoglobulin I-set domain containing protein 0.0196 0.0135 0.0107
Echinococcus granulosus serine:threonine protein kinase PAK 3 0.0267 0.029 0.0262
Entamoeba histolytica hypothetical protein 0.0722 0.1286 0.6449
Onchocerca volvulus 0.0349 0.0469 0.1196
Trichomonas vaginalis CMGC family protein kinase 0.0356 0.0486 0.2438
Echinococcus multilocularis raf serine:threonine protein kinase 0.0271 0.03 0.0273
Echinococcus multilocularis serine:threonine protein kinase 38 0.0574 0.0963 0.0938
Echinococcus multilocularis serine:threonine protein kinase TAO1 0.046 0.0713 0.0687
Echinococcus multilocularis cGMP dependent protein kinase 1 0.0294 0.0349 0.0321
Entamoeba histolytica serine/threonine protein kinase STE20, putative 0.0248 0.0248 0.1246
Trichomonas vaginalis AGC family protein kinase 0.0166 0.0068 0.0343
Loa Loa (eye worm) hypothetical protein 0.0154 0.0043 0.0023
Plasmodium falciparum protein kinase, putative 0.0223 0.0193 0.2151
Brugia malayi Protein kinase domain containing protein 0.0212 0.017 0.0142
Echinococcus multilocularis nervana 2 0.0444 0.0679 0.0653
Brugia malayi Immunoglobulin I-set domain containing protein 0.0747 0.1342 0.1317
Echinococcus multilocularis twitchin 0.0162 0.0059 0.0031
Loa Loa (eye worm) hypothetical protein 0.023 0.021 0.019
Echinococcus granulosus casein kinase I alpha 0.028 0.0319 0.0292
Trichomonas vaginalis STE family protein kinase 0.0267 0.029 0.1454
Echinococcus multilocularis rho associated protein kinase 0.0932 0.1747 0.1724
Echinococcus multilocularis insulin growth factor 1 receptor beta 0.1302 0.2557 0.2536
Trichomonas vaginalis CMGC family protein kinase 0.0209 0.0162 0.0814
Onchocerca volvulus 0.0218 0.0183 0.0435
Brugia malayi Protein kinase domain containing protein 0.0531 0.0868 0.0842
Echinococcus granulosus NDR protein kinase 0.0574 0.0963 0.0938
Echinococcus granulosus Glutaredoxin protein 5 0.0444 0.0679 0.0653
Schistosoma mansoni ephrin receptor 0.0156 0.0048 0.0048
Echinococcus granulosus serine:threonine protein kinase 12 B 0.0475 0.0746 0.072
Loa Loa (eye worm) SRC-1 0.0472 0.0738 0.072
Entamoeba histolytica casein kinase 1, putative 0.028 0.0319 0.1602
Brugia malayi Homeodomain interacting protein kinase protein 1 0.0423 0.0631 0.0605
Echinococcus multilocularis tyrosine kinase 0.0218 0.0183 0.0155
Schistosoma mansoni tyrosine kinase 0.1016 0.193 0.193
Trichomonas vaginalis STE family protein kinase 0.0267 0.029 0.1454
Giardia lamblia Kinase, CMGC GSK 0.0419 0.0623 0.3456
Trichomonas vaginalis AGC family protein kinase 0.1045 0.1994 1
Trypanosoma cruzi kinetoplastid kinetochore protein 10, putative 0.033 0.0428 0.2372
Brugia malayi probable protein kinase 0.0562 0.0936 0.091
Loa Loa (eye worm) CK1/CK1/CK1-A protein kinase 0.028 0.0319 0.03
Schistosoma mansoni serine/threonine protein kinase 0.0522 0.0849 0.0849
Echinococcus multilocularis serine:threonine protein kinase MARK2 0.0855 0.1578 0.1554
Loa Loa (eye worm) TK protein kinase 0.0577 0.097 0.0951
Echinococcus multilocularis casein kinase I alpha 0.028 0.0319 0.0292
Onchocerca volvulus Serine\/threonine kinase homolog 0.035 0.0471 0.1202
Loa Loa (eye worm) hypothetical protein 0.0424 0.0633 0.0614
Schistosoma mansoni tyrosine kinase 0.0472 0.0738 0.0738
Loa Loa (eye worm) CAMK/MLCK protein kinase 0.0196 0.0135 0.0115
Schistosoma mansoni cell adhesion molecule 0.0147 0.0028 0.0028
Loa Loa (eye worm) TK/FER protein kinase 0.0218 0.0183 0.0163
Onchocerca volvulus Serine\/threonine protein kinase homolog 0.0709 0.1258 0.33
Entamoeba histolytica protein kinase , putative 0.0475 0.0746 0.3742
Echinococcus multilocularis c Jun NH2 terminal kinase 0.4701 1 1
Echinococcus granulosus nervana 2 0.0444 0.0679 0.0653
Loa Loa (eye worm) AGC/PKA protein kinase 0.0329 0.0426 0.0407
Echinococcus granulosus leucine rich repeat serine:threonine protein 0.0212 0.017 0.0143
Giardia lamblia Kinase, AGC PKA 0.0329 0.0426 0.2364
Trypanosoma brucei polo-like protein kinase 0.0958 0.1804 0.9048
Trypanosoma brucei rac serine-threonine kinase, putative 0.1045 0.1994 1
Entamoeba histolytica protein kinase, putative 0.0245 0.0242 0.1214
Giardia lamblia Kinase, CMGC MAPK 0.0245 0.0243 0.1345
Schistosoma mansoni serine/threonine protein kinase 0.0958 0.1804 0.1804
Giardia lamblia Kinase, PLK 0.0958 0.1804 1
Echinococcus granulosus activin receptor type 0.0919 0.1717 0.1694
Echinococcus multilocularis leucine rich repeat serine:threonine protein 0.0212 0.017 0.0142
Schistosoma mansoni serine/threonine protein kinase 0.0245 0.0242 0.0242
Schistosoma mansoni serine/threonine protein kinase 0.0469 0.0732 0.0732
Brugia malayi C1-like domain containing protein 0.0599 0.1017 0.0991
Trichomonas vaginalis AGC family protein kinase 0.0475 0.0746 0.3742
Plasmodium falciparum NIMA related kinase 1 0.0394 0.0569 0.633
Brugia malayi Tyrosine-protein kinase abl-1 0.053 0.0867 0.0841
Brugia malayi Protein kinase domain containing protein 0.0272 0.0301 0.0274
Trypanosoma brucei mitogen activated protein kinase 4, putative 0.0245 0.0243 0.1217
Schistosoma mansoni nephrin 0.0147 0.0028 0.0028
Echinococcus granulosus serine:threonine protein kinase mig 15 0.0461 0.0715 0.0689
Echinococcus multilocularis sodium:potassium dependent atpase beta subunit 0.0444 0.0679 0.0653
Plasmodium falciparum serine/threonine protein kinase KIN 0.0251 0.0255 0.2837
Echinococcus multilocularis cyclin dependent kinase 19 0.035 0.0471 0.0444
Echinococcus multilocularis tyrosine protein kinase Fps85D 0.0218 0.0183 0.0155
Toxoplasma gondii cell-cycle-associated protein kinase CLK, putative 0.033 0.0428 0.221
Loa Loa (eye worm) CAMK/TSSK protein kinase 0.1177 0.2283 0.2268
Loa Loa (eye worm) CAMK/PIM protein kinase 0.0709 0.1258 0.1241
Schistosoma mansoni serine/threonine protein kinase 0.0879 0.1631 0.1631
Brugia malayi Protein kinase domain containing protein 0.0196 0.0135 0.0107
Entamoeba histolytica cell division protein kinase 2, putative 0.0386 0.0552 0.2767
Loa Loa (eye worm) CMGC/CDK/CDK5 protein kinase 0.0386 0.0552 0.0533
Echinococcus multilocularis Diacylglycerol kinase theta 0.0149 0.0033 0.0005
Trichomonas vaginalis CAMK family protein kinase 0.0251 0.0255 0.128
Echinococcus granulosus 5'partial|cyclin dependent kinase 1 0.0386 0.0552 0.0525
Echinococcus granulosus titin 0.0196 0.0135 0.0107
Schistosoma mansoni protein kinase 0.0665 0.1163 0.1163
Schistosoma mansoni tyrosine kinase 0.0235 0.022 0.022
Echinococcus granulosus dual specificity 0.0524 0.0854 0.0828
Entamoeba histolytica protein kinase domain containing protein 0.0524 0.0854 0.4283
Schistosoma mansoni serine/threonine protein kinase 0.035 0.0471 0.0471
Toxoplasma gondii casein kinase I 0.028 0.0319 0.165
Echinococcus multilocularis MAP kinase activated protein kinase 2 0.1302 0.2558 0.2537
Brugia malayi Protein kinase domain containing protein 0.0404 0.0591 0.0564
Trypanosoma cruzi Vacuolar sorting protein 39 domain 1/Vacuolar sorting protein 39 domain 2, putative 0.0233 0.0215 0.1195
Brugia malayi Ras association domain family 1 isoform A 0.0149 0.0033 0.0005
Echinococcus multilocularis casein kinase I delta 0.028 0.0319 0.0292
Loa Loa (eye worm) gastrulation defective protein 1 0.0249 0.0251 0.0231
Echinococcus multilocularis cyclin dependent kinase 1 0.0386 0.0552 0.0525
Giardia lamblia Kinase, CK1 Casein kinase 0.028 0.0319 0.1771
Brugia malayi Protein kinase domain containing protein 0.1177 0.2283 0.2262
Loa Loa (eye worm) hypothetical protein 0.0149 0.0033 0.0013
Brugia malayi Protein kinase domain containing protein 0.033 0.0428 0.0401
Entamoeba histolytica protein kinase, putative 0.0231 0.0212 0.1063
Loa Loa (eye worm) TKL/LRRK protein kinase 0.0212 0.017 0.015
Plasmodium vivax rac-beta serine/threonine protein kinase, putative 0.0545 0.0899 1
Echinococcus granulosus STE20 serine:threonine protein kinase 0.0977 0.1844 0.1821
Brugia malayi hypothetical protein 0.0233 0.0215 0.0188
Entamoeba histolytica serine/threonine-protein kinase 3, putative 0.0248 0.0248 0.1246
Trichomonas vaginalis CAMK family protein kinase 0.0251 0.0255 0.128
Echinococcus multilocularis serine:threonine protein kinase N2 0.082 0.1502 0.1478
Trypanosoma cruzi cdc2-related kinase 3 0.0386 0.0552 0.3058
Echinococcus multilocularis casein kinase I gamma 0.0272 0.0301 0.0274
Schistosoma mansoni vam6/vps39 related 0.0233 0.0215 0.0215
Echinococcus granulosus tyrosine kinase 0.0385 0.0549 0.0522
Trichomonas vaginalis CAMK family protein kinase 0.0251 0.0255 0.128
Entamoeba histolytica diacylglycerol kinase, putative 0.0149 0.0033 0.0165
Trichomonas vaginalis AGC family protein kinase 0.0202 0.0147 0.0739
Giardia lamblia Kinase, STE STE20 0.0248 0.0248 0.1377
Trichomonas vaginalis AGC family protein kinase 0.0139 0.0011 0.0056
Echinococcus granulosus activated cdc42 kinase 1 0.0437 0.0663 0.0637
Schistosoma mansoni diacylglycerol kinase theta 0.0149 0.0033 0.0033
Onchocerca volvulus 0.0209 0.0162 0.0379
Trichomonas vaginalis AGC family protein kinase 0.0139 0.0011 0.0056
Echinococcus granulosus mitogen-activated protein kinase kinase kinase 9 0.0301 0.0365 0.0338
Schistosoma mansoni serine/threonine protein kinase 0.0932 0.1747 0.1747
Loa Loa (eye worm) camk/dcamkl protein kinase 0.0324 0.0416 0.0397
Brugia malayi Immunoglobulin I-set domain containing protein 0.1787 0.3619 0.3601
Echinococcus multilocularis basement membrane specific heparan sulfate 0.023 0.021 0.0182
Trichomonas vaginalis AGC family protein kinase 0.0139 0.0011 0.0056
Echinococcus multilocularis tyrosine protein kinase ABL1 0.0808 0.1476 0.1452
Loa Loa (eye worm) hypothetical protein 0.0265 0.0285 0.0266
Trypanosoma brucei protein kinase A catalytic subunit, putative 0.0329 0.0426 0.2139
Echinococcus granulosus C2 calcium dependent membrane targeting 0.0154 0.0043 0.0015
Echinococcus granulosus tyrosine protein kinase Fps85D 0.0218 0.0183 0.0155
Entamoeba histolytica protein kinase, putative 0.0289 0.0338 0.1698
Brugia malayi EST embl|AI107989|AI107989 comes from the 3' UTR, putative 0.0618 0.1059 0.1033
Echinococcus multilocularis tyrosine protein kinase HCK 0.0289 0.0338 0.0311
Echinococcus granulosus mitogen activated protein kinase 11 0.046 0.0713 0.0686
Echinococcus multilocularis death associated protein kinase 1 0.2422 0.5008 0.4994
Trypanosoma brucei protein kinase, putative 0.0245 0.0243 0.1217
Trypanosoma brucei aurora B kinase 0.0475 0.0746 0.3742
Echinococcus granulosus protein kinase shaggy 0.0419 0.0623 0.0597
Schistosoma mansoni serine/threonine protein kinase 0.0469 0.0732 0.0732
Trichomonas vaginalis CAMK family protein kinase 0.0456 0.0705 0.3536
Schistosoma mansoni serine/threonine protein kinase 0.0251 0.0255 0.0255
Plasmodium vivax calcium-dependent protein kinase 4, putative 0.028 0.0318 0.3538
Loa Loa (eye worm) hypothetical protein 0.0265 0.0285 0.0266
Trichomonas vaginalis CMGC family protein kinase 0.0356 0.0486 0.2438
Schistosoma mansoni serine/threonine protein kinase 0.1302 0.2558 0.2558
Trichomonas vaginalis CMGC family protein kinase 0.0419 0.0623 0.3127
Trichomonas vaginalis serine/threonine-protein kinase ypk, putative 0.0139 0.0011 0.0056
Schistosoma mansoni tyrosine kinase 0.0859 0.1587 0.1587
Echinococcus multilocularis ephrin type A receptor 4 A 0.0366 0.0507 0.048
Loa Loa (eye worm) CMGC/CDK/CDC2 protein kinase 0.0386 0.0552 0.0533
Echinococcus multilocularis 0.0229 0.0207 0.018
Loa Loa (eye worm) hypothetical protein 0.0233 0.0215 0.0196
Trichomonas vaginalis AGC family protein kinase 0.0166 0.0068 0.0343
Trichomonas vaginalis AGC family protein kinase 0.1045 0.1994 1
Trypanosoma cruzi STE/STE11 serine/threonine-protein kinase, putative 0.0223 0.0193 0.1072
Schistosoma mansoni serine/threonine protein kinase 0.0484 0.0765 0.0765
Echinococcus multilocularis myotubularin protein 13 0.0176 0.009 0.0062
Schistosoma mansoni serine/threonine protein kinase 0.0209 0.0162 0.0162
Schistosoma mansoni chimerin-related rho-gtpase-activating protein 0.0245 0.0243 0.0243
Echinococcus granulosus serine:threonine protein kinase N2 0.082 0.1502 0.1478
Trypanosoma cruzi kinetoplastid kinetochore protein 10, putative 0.033 0.0428 0.2372
Brugia malayi Dual-specificity tyrosine-phosphorylation regulated kinase 2 0.0201 0.0147 0.0119
Schistosoma mansoni hypothetical protein 0.0205 0.0154 0.0154
Echinococcus granulosus Immunoglobulin 0.023 0.021 0.0182
Echinococcus granulosus macrophage colony stimulating factor 1 receptor 0.3421 0.7196 0.7188
Plasmodium falciparum RAC-beta serine/threonine protein kinase 0.0545 0.0899 1
Schistosoma mansoni serine/threonine protein kinase 0.074 0.1325 0.1325
Echinococcus multilocularis dual specificity 0.0201 0.0147 0.0119
Brugia malayi ribosomal protein S6 kinase alpha 3 0.0421 0.0627 0.0601
Loa Loa (eye worm) STE/STE20/KHS protein kinase 0.0755 0.1359 0.1342
Trichomonas vaginalis AGC family protein kinase 0.0139 0.0011 0.0056
Loa Loa (eye worm) CAMK/CAMKL/AMPK protein kinase 0.0618 0.1059 0.1041
Trypanosoma brucei CMGC/DYRK protein kinase, putative 0.0524 0.0854 0.4283
Schistosoma mansoni hypothetical protein 0.0149 0.0033 0.0033
Echinococcus multilocularis hypothetical protein 0.0368 0.0512 0.0485
Echinococcus granulosus TGF beta receptor type 1 0.0237 0.0225 0.0197
Trichomonas vaginalis AGC family protein kinase 0.0166 0.0068 0.0343
Schistosoma mansoni serine/threonine protein kinase 0.028 0.0318 0.0318
Echinococcus multilocularis tyrosine protein kinase shark 0.0218 0.0183 0.0155
Toxoplasma gondii CMGC kinase, CK2 family 0.0356 0.0486 0.251
Echinococcus granulosus epidermal growth factor receptor 0.173 0.3495 0.3476
Trichomonas vaginalis CAMK family protein kinase 0.0202 0.0147 0.0739
Toxoplasma gondii histone kinase SNF1, putative 0.0251 0.0255 0.1318
Entamoeba histolytica protein kinase, putative 0.0475 0.0746 0.3742
Echinococcus granulosus tyrosine kinase 0.0218 0.0183 0.0155
Trypanosoma brucei cdc2-related kinase 3 0.0386 0.0552 0.2767
Trichomonas vaginalis CK1 family protein kinase 0.028 0.0319 0.1602
Schistosoma mansoni serine/threonine protein kinase 0.0345 0.046 0.046
Schistosoma mansoni serine/threonine protein kinase 0.4701 1 1
Brugia malayi Phorbol esters/diacylglycerol binding domain 0.0599 0.1017 0.0991
Entamoeba histolytica serine/threonine- protein kinase 6, putative 0.0475 0.0746 0.3742
Onchocerca volvulus 0.0218 0.0183 0.0435
Echinococcus multilocularis rac serine:threonine kinase 0.0571 0.0957 0.0931
Giardia lamblia Kinase, CMGC GSK 0.0419 0.0623 0.3456
Brugia malayi Temporarily assigned gene name protein 59 0.0491 0.0781 0.0755
Trypanosoma cruzi p21-activated kinase 3, putative 0.0162 0.0061 0.034
Trichomonas vaginalis CAMK family protein kinase 0.0251 0.0255 0.128
Plasmodium vivax casein kinase 1, putative 0.028 0.0319 0.3552
Loa Loa (eye worm) AGC/PKA protein kinase 0.0329 0.0426 0.0407
Toxoplasma gondii protein kinase, cAMP-dependent, catalytic chain 0.0329 0.0426 0.2202
Schistosoma mansoni serine/threonine protein kinase 0.0879 0.1631 0.1631
Loa Loa (eye worm) TK/FER protein kinase 0.0218 0.0183 0.0163
Echinococcus granulosus tyrosine protein kinase Btk29A 0.0243 0.0239 0.0211
Trichomonas vaginalis AGC family protein kinase 0.0166 0.0068 0.0343
Schistosoma mansoni diacylglycerol kinase theta 0.0149 0.0033 0.0033
Brugia malayi map kinase activated protein kinase protein 2 0.1302 0.2558 0.2537
Echinococcus granulosus basic fibroblast growth factor receptor 1 A 0.0686 0.1209 0.1184
Echinococcus granulosus Vam6:Vps39 protein 0.0233 0.0215 0.0188
Entamoeba histolytica protein kinase, putative 0.0524 0.0854 0.4283
Echinococcus granulosus Rac GTPase activating protein 1 0.0149 0.0033 0.0005
Trichomonas vaginalis AGC family protein kinase 0.0139 0.0011 0.0056
Schistosoma mansoni tyrosine kinase 0.0243 0.0239 0.0239
Trichomonas vaginalis STE family protein kinase 0.0242 0.0235 0.1177
Trypanosoma brucei cdc2-related kinase 1 0.0386 0.0552 0.2767
Loa Loa (eye worm) CMGC/CDK/CDK8 protein kinase 0.035 0.0471 0.0452
Entamoeba histolytica protein kinase, putative 0.0475 0.0746 0.3742
Schistosoma mansoni rac gtpase activating protein 0.0149 0.0033 0.0033
Loa Loa (eye worm) hypothetical protein 0.0343 0.0457 0.0438
Leishmania major protein kinase A catalytic subunit 0.0329 0.0426 0.2364
Echinococcus multilocularis mitogen activated protein kinase 14 0.046 0.0713 0.0686
Loa Loa (eye worm) hypothetical protein 0.0453 0.0697 0.0679
Giardia lamblia Kinase, CMGC CDK 0.0386 0.0552 0.3058
Echinococcus multilocularis dual specificity testis specific protein kinase 0.0665 0.1163 0.1138
Trichomonas vaginalis CK1 family protein kinase 0.028 0.0319 0.1602
Brugia malayi Serine/threonine-protein kinase Pim-3 0.0709 0.1258 0.1234
Loa Loa (eye worm) variant SH3 domain-containing protein 0.0183 0.0106 0.0086
Echinococcus multilocularis cGMP dependent protein kinase 1 0.0294 0.0349 0.0321
Loa Loa (eye worm) STE/STE20/TAO protein kinase 0.046 0.0713 0.0694
Brugia malayi Protein kinase domain containing protein 0.0239 0.0229 0.0201
Loa Loa (eye worm) hypothetical protein 0.0437 0.0663 0.0644
Giardia lamblia Kinase, CMGC CLK 0.033 0.0428 0.2372
Echinococcus multilocularis GTPase activating Rap:RanGAP domain 3 0.0233 0.0215 0.0188
Loa Loa (eye worm) CMGC/CK2 protein kinase 0.0356 0.0486 0.0467
Echinococcus granulosus myotubularin protein 13 0.0176 0.009 0.0062
Schistosoma mansoni protein kinase 0.0475 0.0746 0.0746
Echinococcus granulosus dual specificity testis-specific protein kinase 0.0665 0.1163 0.1138
Plasmodium falciparum casein kinase 2, alpha subunit 0.0356 0.0486 0.5404
Leishmania major protein kinase, putative,dual-specificity protein kinase, putative 0.0201 0.0147 0.0812
Trypanosoma brucei cAMP-dependent protein kinase catalytic subunit 2 0.0329 0.0426 0.2139
Mycobacterium ulcerans hypothetical protein 0.0193 0.0128 0.5
Schistosoma mansoni unc-13 (munc13) 0.0154 0.0043 0.0043
Trichomonas vaginalis CAMK family protein kinase 0.0251 0.0255 0.128
Loa Loa (eye worm) hypothetical protein 0.0176 0.009 0.007
Brugia malayi Protein kinase domain 0.0267 0.029 0.0262
Echinococcus granulosus enhancer of mRNA decapping protein 4 0.0228 0.0206 0.0178
Brugia malayi Protein kinase domain containing protein 0.0202 0.0147 0.0119
Schistosoma mansoni proto-oncogene tyrosine-protein kinase abl1 0.0183 0.0106 0.0106
Echinococcus granulosus raf serine:threonine protein kinase 0.0271 0.03 0.0273
Trypanosoma cruzi mitogen-activated protein kinase 11, putative 0.0245 0.0243 0.1345
Loa Loa (eye worm) hypothetical protein 0.0265 0.0285 0.0266
Loa Loa (eye worm) thyroid receptor interactor 0.0223 0.0194 0.0174
Trichomonas vaginalis STE family protein kinase 0.0267 0.029 0.1454
Loa Loa (eye worm) hypothetical protein 0.0149 0.0033 0.0013
Loa Loa (eye worm) CAMK/PKD protein kinase 0.0449 0.0689 0.0671
Echinococcus granulosus tyrosine protein kinase Lyn 0.0572 0.0959 0.0933
Echinococcus multilocularis enhancer of mRNA decapping protein 4 0.0228 0.0206 0.0178
Echinococcus multilocularis calcium:calmodulin dependent protein kinase I 0.0245 0.0242 0.0214
Loa Loa (eye worm) AGC/RSK/P70 protein kinase 0.1019 0.1936 0.192
Loa Loa (eye worm) CMGC/GSK protein kinase 0.0419 0.0623 0.0605
Echinococcus granulosus serine:threonine protein kinase 0.0487 0.0771 0.0745
Trichomonas vaginalis AGC family protein kinase 0.0139 0.0011 0.0056
Brugia malayi serine/threonine-protein kinase 6 0.0475 0.0746 0.072
Echinococcus multilocularis ribosomal protein s6 kinase beta 1 0.0574 0.0963 0.0938
Echinococcus multilocularis tyrosine protein kinase lyn tyrosine protein kinase blk 0.0472 0.0738 0.0712
Giardia lamblia Kinase, CMGC CDK 0.0386 0.0552 0.3058
Loa Loa (eye worm) AGC/PKG protein kinase 0.0294 0.0349 0.0329
Loa Loa (eye worm) CAMKK/META protein kinase 0.0202 0.0147 0.0127
Trichomonas vaginalis AGC family protein kinase 0.0166 0.0068 0.0343
Giardia lamblia Kinase, AGC PKA 0.0545 0.0899 0.4986
Schistosoma mansoni serine/threonine protein kinase 0.0251 0.0255 0.0255
Echinococcus multilocularis 0.0329 0.0426 0.0399
Echinococcus multilocularis dual specificity mitogen activated protein 0.0242 0.0235 0.0207
Toxoplasma gondii Tyrosine kinase-like (TKL) protein 0.0192 0.0126 0.065
Trichomonas vaginalis AGC family protein kinase 0.0139 0.0011 0.0056
Schistosoma mansoni serine/threonine kinase 0.0574 0.0963 0.0963
Trichomonas vaginalis AGC family protein kinase 0.0202 0.0147 0.0739
Echinococcus multilocularis serine:threonine protein kinase MRCK beta 0.0667 0.1167 0.1142
Trichomonas vaginalis AGC family protein kinase 0.0166 0.0068 0.0343
Echinococcus granulosus tyrosine protein kinase Src42A 0.0472 0.0738 0.0712
Schistosoma mansoni serine/threonine protein kinase 0.0251 0.0255 0.0255
Trichomonas vaginalis CMGC family protein kinase 0.033 0.0428 0.2146
Entamoeba histolytica protein kinase, putative 0.1045 0.1994 1
Plasmodium falciparum calcium-dependent protein kinase 3 0.028 0.0318 0.3538
Leishmania major casein kinase, putative 0.028 0.0319 0.1771
Entamoeba histolytica protein kinase domain containing protein 0.0419 0.0623 0.3127
Schistosoma mansoni hypothetical protein 0.0205 0.0154 0.0154
Trypanosoma brucei mitogen-activated protein kinase 3, putative 0.046 0.0713 0.3574
Echinococcus multilocularis calcium:calmodulin dependent protein kinase type 0.028 0.0318 0.0291
Brugia malayi Protein kinase domain containing protein 0.0218 0.0183 0.0155
Echinococcus multilocularis maternal embryonic leucine zipper kinase 0.0257 0.0268 0.024
Echinococcus granulosus Serine:threonine protein kinase PLK4 0.0419 0.0623 0.0597
Schistosoma mansoni serine/threonine protein kinase 0.0294 0.0349 0.0349
Schistosoma mansoni protein kinase C 0.0154 0.0043 0.0043
Echinococcus granulosus tyrosine protein kinase Btk29A 0.0938 0.1759 0.1735
Schistosoma mansoni ste20-related kinase 0.0591 0.0999 0.0999
Brugia malayi serine/threonine kinase 12 0.0475 0.0746 0.072
Trichomonas vaginalis CMGC family protein kinase 0.0201 0.0147 0.0735
Echinococcus granulosus mitogen activated protein kinase kinase kinase 0.0333 0.0436 0.0409
Loa Loa (eye worm) CAMK/TSSK protein kinase 0.1177 0.2283 0.2268
Trichomonas vaginalis CMGC family protein kinase 0.0419 0.0623 0.3127
Onchocerca volvulus 0.0218 0.0183 0.0435
Trypanosoma cruzi STE/STE20 serine/threonine-protein kinase, putative 0.0162 0.0061 0.034
Echinococcus multilocularis tyrosine protein kinase Fgr 0.0472 0.0738 0.0712
Loa Loa (eye worm) AGC/PDK1 protein kinase 0.0239 0.0229 0.0209
Echinococcus multilocularis mitogen activated protein kinase 14 0.046 0.0713 0.0686
Trypanosoma cruzi mitogen-activated protein kinase 11, putative 0.0245 0.0243 0.1345
Echinococcus multilocularis expressed conserved protein 0.0294 0.0349 0.0321
Trichomonas vaginalis CAMK family protein kinase 0.0202 0.0147 0.0739
Brugia malayi phosphoinositide-dependent protein kinase I 0.0239 0.0229 0.0201
Trypanosoma brucei protein kinase, putative 0.0419 0.0623 0.3127
Echinococcus granulosus cyclin dependent kinase 0.0386 0.0552 0.0525
Echinococcus granulosus casein kinase ii subunit alpha 0.0356 0.0486 0.0459
Schistosoma mansoni serine/threonine protein kinase 0.0271 0.03 0.03
Echinococcus granulosus Diacylglycerol kinase theta 0.0149 0.0033 0.0005
Echinococcus multilocularis tyrosine protein kinase Abl 0.053 0.0867 0.0841
Trypanosoma cruzi polo-like protein kinase, putative 0.0958 0.1804 1
Schistosoma mansoni mitogen-activated protein kinase kinase kinase 3 mapkkk3 mekk3 0.0233 0.0215 0.0215
Schistosoma mansoni titin 0.0196 0.0135 0.0135
Loa Loa (eye worm) CMGC/DYRK/DYRK1 protein kinase 0.0524 0.0854 0.0835
Trichomonas vaginalis CAMK family protein kinase 0.0251 0.0255 0.128
Entamoeba histolytica casein kinase, putative 0.028 0.0319 0.1602
Echinococcus granulosus mitogen activated protein kinase 3 0.0245 0.0243 0.0215
Onchocerca volvulus Serine\/threonine kinase homolog 0.0958 0.1804 0.4753
Echinococcus multilocularis homeodomain interacting protein kinase 3 0.0423 0.0631 0.0605
Echinococcus multilocularis roundabout 2 0.0378 0.0532 0.0506
Schistosoma mansoni tyrosine kinase 0.0218 0.0183 0.0183
Echinococcus granulosus serine/threonine protein kinase 0.0571 0.0957 0.0931
Entamoeba histolytica protein kinase, putative 0.0196 0.0135 0.0675
Leishmania major protein kinase, putative 0.0248 0.0248 0.1377
Brugia malayi Calcium/calmodulin-dependent protein kinase type II alpha chain 0.028 0.0318 0.0291
Entamoeba histolytica protein kinase, putative 0.0197 0.0136 0.0684
Schistosoma mansoni serine/threonine protein kinase 0.0162 0.0059 0.0059
Echinococcus granulosus casein kinase i 0.028 0.0319 0.0292
Loa Loa (eye worm) hypothetical protein 0.0149 0.0033 0.0013
Onchocerca volvulus 0.0218 0.0183 0.0435
Entamoeba histolytica diacylglycerol kinase, putative 0.0149 0.0033 0.0165
Trypanosoma brucei Casein kinase II 0.0356 0.0486 0.2438
Echinococcus granulosus calcium:calmodulin dependent protein kinase type 0.028 0.0318 0.0291
Trichomonas vaginalis cAMP-dependent protein kinase catalytic subunit, putative 0.0139 0.0011 0.0056
Loa Loa (eye worm) STE/STE20/PAKB protein kinase 0.0844 0.1553 0.1536
Echinococcus multilocularis 5' AMP activated protein kinase catalytic 0.0618 0.1059 0.1033
Loa Loa (eye worm) STE/STE7/MEK1 protein kinase 0.0242 0.0235 0.0215
Trichomonas vaginalis STE family protein kinase 0.0267 0.029 0.1454
Echinococcus granulosus homeodomain interacting protein kinase 3 0.0423 0.0631 0.0605
Leishmania major protein kinase, putative 0.0223 0.0193 0.1072
Echinococcus granulosus aurora kinase A 0.0475 0.0746 0.072
Plasmodium vivax calcium-dependent protein kinase 1, putative 0.028 0.0318 0.3538
Loa Loa (eye worm) hypothetical protein 0.015 0.0035 0.0015
Entamoeba histolytica SH2-protein kinase domain containing protein 0.0218 0.0183 0.0919
Echinococcus multilocularis ribosomal protein S6 kinase alpha 3 0.0894 0.1664 0.1641
Echinococcus multilocularis epidermal growth factor receptor 0.1138 0.2197 0.2175
Loa Loa (eye worm) CAMK/PKD protein kinase 0.0599 0.1017 0.0998
Schistosoma mansoni protein kinase 0.0237 0.0225 0.0225
Onchocerca volvulus 0.0932 0.1747 0.4603
Echinococcus multilocularis TGF beta receptor type 1 0.0237 0.0225 0.0197
Loa Loa (eye worm) CAMK/PIM protein kinase 0.0709 0.1258 0.1241
Echinococcus multilocularis serine:threonine protein kinase MARK2 0.0855 0.1578 0.1554
Trypanosoma cruzi mitogen-activated protein kinase 3, putative 0.046 0.0713 0.3951
Trypanosoma cruzi aurora B kinase, putative 0.0475 0.0746 0.4135
Plasmodium vivax protein kinase, putative 0.016 0.0057 0.063
Brugia malayi Protein kinase domain containing protein 0.1857 0.3772 0.3755
Echinococcus granulosus tyrosine protein kinase Fyn 0.0472 0.0738 0.0712
Echinococcus multilocularis epidermal growth factor receptor 0.173 0.3495 0.3476
Trypanosoma brucei calcium/calmodulin-dependent protein kinase, putative 0.028 0.0318 0.1596
Echinococcus multilocularis mitogen activated protein kinase 3 0.0245 0.0243 0.0215
Plasmodium vivax cAMP-dependent protein kinase catalytic subunit, putative 0.0329 0.0426 0.4741
Trichomonas vaginalis STE family protein kinase 0.0394 0.0569 0.2856
Brugia malayi intracellular kinase 0.0419 0.0623 0.0597
Loa Loa (eye worm) CMGC/MAPK/P38 protein kinase 0.046 0.0713 0.0694
Giardia lamblia Kinase, STE STE20 0.0267 0.029 0.1607
Echinococcus multilocularis aurora kinase A 0.0475 0.0746 0.072
Brugia malayi Protein kinase domain containing protein 0.0709 0.1258 0.1234
Schistosoma mansoni serine/threonine protein kinase 0.035 0.0471 0.0471
Brugia malayi Furin-like cysteine rich region family protein 0.173 0.3495 0.3476
Loa Loa (eye worm) AUR protein kinase 0.0475 0.0746 0.0727
Onchocerca volvulus 0.0218 0.0183 0.0435
Loa Loa (eye worm) hypothetical protein 0.0149 0.0033 0.0013
Brugia malayi Protein kinase domain containing protein 0.0156 0.0046 0.0018
Plasmodium vivax tyrosine kinase-like protein, putative 0.0192 0.0126 0.14
Plasmodium vivax unspecified product 0.0356 0.0486 0.5404
Brugia malayi protein kinase C II. 0.0728 0.1301 0.1276
Trichomonas vaginalis AGC family protein kinase 0.0139 0.0011 0.0056
Trichomonas vaginalis mitogen-activated protein kinase kinase kinase 3, MAPKKK3, MEKK3, putative 0.0162 0.0061 0.0308
Echinococcus granulosus dual specificity mitogen activated protein 0.0242 0.0235 0.0207
Echinococcus multilocularis proto oncogene serine:threonine protein kinase 0.0709 0.1258 0.1234
Trichomonas vaginalis CMGC family protein kinase 0.0201 0.0147 0.0735
Echinococcus granulosus tyrosine kinase|tyrosine protein kinase Fyn 0.0385 0.0549 0.0522
Brugia malayi diacylglycerol kinase 0.0149 0.0033 0.0005
Echinococcus granulosus mitogen activated protein kinase 14 0.046 0.0713 0.0686
Brugia malayi Protein kinase domain containing protein 0.0218 0.0183 0.0155
Giardia lamblia Kinase, NEK 0.0394 0.0569 0.3156
Trypanosoma cruzi serine/arginine-rich protein specific kinase SRPK, putative 0.0196 0.0135 0.0746
Entamoeba histolytica protein kinase, putative 0.028 0.0318 0.1596
Loa Loa (eye worm) raf kinase 0.0149 0.0033 0.0013
Giardia lamblia Kinase, AGC AKT 0.0421 0.0627 0.3478
Echinococcus multilocularis serine:threonine protein kinase 0.0487 0.0771 0.0745
Loa Loa (eye worm) TK protein kinase 0.0747 0.1342 0.1324
Entamoeba histolytica p21-activated kinase 0.0293 0.0347 0.1741
Trichomonas vaginalis serine/threonine-protein kinase sgk, putative 0.0512 0.0828 0.4152
Schistosoma mansoni receptor tyrosine phosphatase type r2a 0.0147 0.0028 0.0028
Schistosoma mansoni serine/threonine protein kinase 0.0196 0.0135 0.0135
Trichomonas vaginalis AGC family protein kinase 0.0139 0.0011 0.0056
Schistosoma mansoni chimerin-related rho-gtpase-activating protein 0.0245 0.0243 0.0243
Trichomonas vaginalis AGC family protein kinase 0.1045 0.1994 1
Loa Loa (eye worm) hypothetical protein 0.0183 0.0106 0.0086
Echinococcus multilocularis cyclin dependent kinase 1 0.0386 0.0552 0.0525
Brugia malayi Pleckstrin Homology Domain 0.0176 0.009 0.0062
Schistosoma mansoni tyrosine kinase 0.0712 0.1266 0.1266
Echinococcus granulosus tyrosine protein kinase Fyn 0.0472 0.0738 0.0712
Schistosoma mansoni serine/threonine protein kinase 0.0272 0.0301 0.0301
Loa Loa (eye worm) CMGC/GSK protein kinase 0.0419 0.0623 0.0605
Echinococcus multilocularis proto oncogene tyrosine protein kinase LCK 0.0472 0.0738 0.0712
Loa Loa (eye worm) CAMK/CAMKL/MARK protein kinase 0.0487 0.0771 0.0753
Schistosoma mansoni proto-oncogene tyrosine-protein kinase src 0.0305 0.0373 0.0373
Schistosoma mansoni serine/threonine protein kinase 0.033 0.0428 0.0428
Brugia malayi Dual specificity mitogen-activated protein kinase kinase mek-2 0.0242 0.0235 0.0207
Echinococcus granulosus serine:threonine protein kinase Chk2 0.0245 0.0242 0.0214
Loa Loa (eye worm) CMGC/DYRK/HIPK protein kinase 0.0423 0.0631 0.0613
Entamoeba histolytica protein kinase, putative 0.0201 0.0147 0.0735
Echinococcus multilocularis serine:threonine protein kinase N2 0.0246 0.0245 0.0217
Schistosoma mansoni serine/threonine protein kinase 0.0201 0.0147 0.0147
Toxoplasma gondii NIMA-related protein kinase NIMA1 0.0394 0.0569 0.294
Echinococcus multilocularis cyclin dependent kinase 0.0386 0.0552 0.0525
Echinococcus multilocularis activin receptor type 0.0919 0.1717 0.1694
Loa Loa (eye worm) AGC/PKC/IOTA protein kinase 0.0589 0.0995 0.0977
Trichomonas vaginalis AGC family protein kinase 0.0166 0.0068 0.0343
Echinococcus multilocularis serine:threonine protein kinase receptor R3 0.0237 0.0225 0.0197
Echinococcus granulosus rho-associated protein kinase 1 0.0932 0.1747 0.1724
Trichomonas vaginalis CAMK family protein kinase 0.0487 0.0771 0.387
Schistosoma mansoni mitogen-activated protein kinase kinase kinase 3 mapkkk3 mekk3 0.0233 0.0215 0.0215
Loa Loa (eye worm) AGC/AKT protein kinase 0.1045 0.1994 0.1977
Giardia lamblia Kinase, CMGC SRPK 0.0196 0.0135 0.0746
Brugia malayi Protein kinase domain containing protein 0.0386 0.0552 0.0525
Echinococcus multilocularis p21 activated protein kinase 1 Dpak1 0.0267 0.029 0.0262
Trypanosoma cruzi polo-like protein kinase, putative 0.0958 0.1804 1
Toxoplasma gondii calcium dependent protein kinase CDPK8 0.0223 0.0193 0.0999
Brugia malayi RhoGAP domain containing protein 0.0245 0.0243 0.0216
Brugia malayi Protein kinase domain containing protein 0.1094 0.2102 0.208
Entamoeba histolytica protein kinase 2, putative 0.0545 0.0899 0.4511
Plasmodium vivax serine/threonine protein kinase, putative 0.0196 0.0135 0.1497
Echinococcus multilocularis expressed protein 0.0196 0.0135 0.0107
Echinococcus granulosus twitchin 0.0392 0.0564 0.0537
Trichomonas vaginalis CAMK family protein kinase 0.0251 0.0255 0.128
Brugia malayi serine/threonine-protein kinase plk-2 0.0958 0.1804 0.1781
Schistosoma mansoni serine/threonine kinase 0.0625 0.1074 0.1074
Trichomonas vaginalis CAMK family protein kinase 0.0251 0.0255 0.128
Trypanosoma brucei cAMP-dependent protein kinase catalytic subunit 1 0.0329 0.0426 0.2139
Entamoeba histolytica protein kinase, putative 0.0231 0.0212 0.1063
Loa Loa (eye worm) STE/STE20/MST protein kinase 0.0738 0.1322 0.1304
Echinococcus multilocularis calcium:calmodulin dependent protein kinase type 0.0807 0.1473 0.1449
Loa Loa (eye worm) AGC/DMPK/GEK protein kinase 0.125 0.2443 0.2427
Echinococcus granulosus tyrosine protein kinase Blk 0.0385 0.0549 0.0522
Loa Loa (eye worm) CMGC/MAPK/JNK protein kinase 0.4701 1 1
Trichomonas vaginalis CMGC family protein kinase 0.0245 0.0243 0.1217
Schistosoma mansoni serine/threonine protein kinase 0.046 0.0713 0.0713
Echinococcus granulosus [G-protein-coupledreceptor] kinase 0.032 0.0407 0.038
Loa Loa (eye worm) hypothetical protein 0.0229 0.0207 0.0188
Brugia malayi Protein kinase domain containing protein 0.0437 0.0663 0.0637
Loa Loa (eye worm) sex muscle abnormal protein 5 0.0183 0.0106 0.0086
Trichomonas vaginalis AGC family protein kinase 0.0139 0.0011 0.0056
Entamoeba histolytica protein kinase, putative 0.1045 0.1994 1
Echinococcus granulosus serine threonine protein kinase nrc 0.0545 0.0899 0.0874
Loa Loa (eye worm) TK/FER protein kinase 0.0218 0.0183 0.0163
Echinococcus granulosus tyrosine protein kinase 0.0577 0.097 0.0944
Brugia malayi Doublecortin family protein 0.0324 0.0416 0.0389
Loa Loa (eye worm) Ras association domain family 1 isoform A 0.0149 0.0033 0.0013
Brugia malayi Protein kinase domain containing protein 0.1045 0.1994 0.1971
Echinococcus granulosus cyclin dependent kinase 5 0.0386 0.0552 0.0525
Echinococcus multilocularis neuroglian 0.0291 0.0343 0.0316
Schistosoma mansoni serine/threonine protein kinase 0.082 0.1502 0.1502
Brugia malayi Fibronectin type III domain containing protein 0.0265 0.0285 0.0258
Schistosoma mansoni vav2 0.0272 0.03 0.03
Trypanosoma brucei dual specificity tyrosine-phosphorylation-regulated kinase 2, putative 0.0201 0.0147 0.0735
Onchocerca volvulus 0.0792 0.144 0.3783
Echinococcus multilocularis protein tyrosine kinase 0.1083 0.2077 0.2055
Schistosoma mansoni protein kinase 0.0356 0.0486 0.0486
Echinococcus granulosus insulin growth factor 1 receptor beta 0.1302 0.2557 0.2536
Trypanosoma cruzi casein kinase, putative 0.028 0.0319 0.1771
Echinococcus granulosus tyrosine protein kinase Srms 0.0218 0.0183 0.0155
Plasmodium falciparum cAMP-dependent protein kinase catalytic subunit 0.0329 0.0426 0.4741
Echinococcus granulosus 5' AMP activated protein kinase catalytic 0.0618 0.1059 0.1033
Brugia malayi hypothetical protein 0.015 0.0035 0.0007
Loa Loa (eye worm) hypothetical protein 0.0792 0.144 0.1422
Loa Loa (eye worm) AGC/NDR protein kinase 0.0574 0.0963 0.0945
Schistosoma mansoni serine/threonine protein kinase 0.0162 0.0061 0.0061
Echinococcus multilocularis casein kinase I alpha 0.028 0.0319 0.0292
Echinococcus granulosus serine:threonine protein kinase PLK1 0.0958 0.1804 0.1781
Brugia malayi Protein kinase domain containing protein 0.0755 0.1359 0.1335
Echinococcus multilocularis dual specificity 0.0201 0.0147 0.0119
Onchocerca volvulus 0.1383 0.2733 0.7231
Trypanosoma cruzi cAMP-dependent protein kinase catalytic subunit 3 0.0329 0.0426 0.2364
Brugia malayi Protein kinase domain containing protein 0.0625 0.1074 0.1048
Trichomonas vaginalis AGC family protein kinase 0.0329 0.0426 0.2139
Schistosoma mansoni serine/threonine protein kinase 0.0386 0.0552 0.0552
Trichomonas vaginalis AGC family protein kinase 0.0139 0.0011 0.0056
Trypanosoma brucei casein kinase I, isoform 2 0.028 0.0319 0.1602
Trichomonas vaginalis CMGC family protein kinase 0.0201 0.0147 0.0735
Trypanosoma cruzi dual specificity tyrosine-phosphorylation-regulated kinase 2, putative 0.0201 0.0147 0.0812
Giardia lamblia Kinase, CDC7 0.0209 0.0162 0.09
Loa Loa (eye worm) hypothetical protein 0.0487 0.0771 0.0753
Trichomonas vaginalis CAMK family protein kinase 0.0251 0.0255 0.128
Schistosoma mansoni serine/threonine protein kinase 0.033 0.0428 0.0428
Loa Loa (eye worm) hypothetical protein 0.0343 0.0457 0.0438
Trichomonas vaginalis CAMK family protein kinase 0.0958 0.1804 0.9048
Trichomonas vaginalis AGC family protein kinase 0.0202 0.0147 0.0739
Onchocerca volvulus 0.028 0.0319 0.0798
Echinococcus granulosus unc 13 munc13 0.0154 0.0043 0.0015
Loa Loa (eye worm) TK/INSR protein kinase 0.1268 0.2481 0.2466
Toxoplasma gondii cell-cycle-associated protein kinase SRPK, putative 0.0196 0.0135 0.0695
Brugia malayi Protein kinase domain containing protein 0.0574 0.0963 0.0938
Trichomonas vaginalis AGC family protein kinase 0.0139 0.0011 0.0056
Trichomonas vaginalis AGC family protein kinase 0.0239 0.0229 0.1147
Echinococcus multilocularis unc 13 (munc13) 0.0154 0.0043 0.0015
Entamoeba histolytica casein kinase, putative 0.0356 0.0486 0.2438
Loa Loa (eye worm) hypothetical protein 0.0792 0.144 0.1422
Echinococcus multilocularis tyrosine protein kinase Blk 0.0385 0.0549 0.0522
Echinococcus multilocularis transfer RNA-Thr 0.0437 0.0663 0.0637
Loa Loa (eye worm) hypothetical protein 0.0149 0.0032 0.0012
Schistosoma mansoni tyrosine kinase 0.0305 0.0373 0.0373
Loa Loa (eye worm) CMGC/CDK/CDC2 protein kinase 0.0386 0.0552 0.0533
Echinococcus granulosus protein kinase C gamma type 0.073 0.1304 0.128
Loa Loa (eye worm) AGC/PKC/ALPHA protein kinase 0.0256 0.0267 0.0248
Echinococcus granulosus insulin receptor 0.1268 0.2481 0.246
Brugia malayi Protein kinase domain containing protein 0.0613 0.1048 0.1023
Entamoeba histolytica protein kinase, putative 0.0524 0.0854 0.4283
Echinococcus multilocularis Immunoglobulin 0.023 0.021 0.0182
Leishmania major protein kinase, putative 0.033 0.0428 0.2372
Echinococcus granulosus casein kinase I gamma 0.0272 0.0301 0.0274
Trichomonas vaginalis AGC family protein kinase 0.0166 0.0068 0.0343
Plasmodium falciparum glycogen synthase kinase 3 0.0419 0.0623 0.6932
Echinococcus granulosus guanine nucleotide exchange factor VAV2 0.0245 0.0243 0.0216
Schistosoma mansoni glycogen synthase kinase 3-related (gsk3) (cmgc group III) 0.0419 0.0623 0.0623
Trypanosoma cruzi rac serine-threonine kinase, putative 0.0571 0.0957 0.5304
Schistosoma mansoni serine/threonine protein kinase 0.0524 0.0854 0.0854
Schistosoma mansoni serine/threonine protein kinase 0.0618 0.1059 0.1059
Brugia malayi Calcium/calmodulin-dependent protein kinase type II alpha chain 0.0527 0.086 0.0835
Schistosoma mansoni protein kinase C mu 0.0599 0.1017 0.1017
Schistosoma mansoni adapter molecule crk 0.0183 0.0106 0.0106
Loa Loa (eye worm) casein kinase 0.0171 0.0081 0.0061
Brugia malayi Protein kinase domain containing protein 0.0217 0.0181 0.0153
Trypanosoma cruzi kinetoplastid kinetochore protein 19, putative 0.033 0.0428 0.2372
Echinococcus multilocularis calcium dependent protein kinase 0.0179 0.0098 0.007
Toxoplasma gondii cell-cycle-associated protein kinase DYRK2, putative 0.0201 0.0147 0.0757
Echinococcus multilocularis Protein kinase C, brain isozyme 0.0879 0.1631 0.1608
Echinococcus granulosus TGF-beta receptor type-1 0.0237 0.0225 0.0197
Echinococcus multilocularis serine:threonine protein kinase Chk2 0.0245 0.0242 0.0214
Schistosoma mansoni tyrosine kinase 0.0305 0.0373 0.0373
Echinococcus multilocularis tyrosine protein kinase Fyn 0.0472 0.0738 0.0712
Echinococcus multilocularis cAMP dependent protein kinase catalytic subunit 0.0329 0.0426 0.0399
Echinococcus granulosus calcium dependent protein kinase 0.0179 0.0098 0.007
Leishmania major protein kinase A catalytic subunit isoform 2 0.0329 0.0426 0.2364
Trypanosoma cruzi cdc2-related kinase 1 0.0386 0.0552 0.3058
Trichomonas vaginalis conserved hypothetical protein 0.0166 0.0069 0.0348
Leishmania major protein kinase, putative 0.033 0.0428 0.2372
Schistosoma mansoni neuroglian 0.0147 0.0028 0.0028
Schistosoma mansoni growth factor receptor-bound protein 0.0183 0.0106 0.0106
Loa Loa (eye worm) STE/STE20/PAKA protein kinase 0.0162 0.0061 0.0041
Echinococcus granulosus calcium activated potassium channel 0.0469 0.0732 0.0706
Echinococcus multilocularis serine:threonine protein kinase PAK 3 0.0267 0.029 0.0262
Leishmania major protein kinase, putative,polo-like protein kinase, putative 0.0958 0.1804 1
Toxoplasma gondii diacylglycerol kinase, putative 0.0149 0.0033 0.017
Echinococcus granulosus Ribosomal protein S6 kinase beta 2 0.0574 0.0963 0.0938
Entamoeba histolytica protein kinase, putative 0.0196 0.0135 0.0675
Trypanosoma cruzi casein kinase, delta isoform, putative 0.018 0.0099 0.0549
Plasmodium falciparum protein kinase 5 0.0386 0.0552 0.6133
Loa Loa (eye worm) TKL/STKR/TYPE1 protein kinase 0.0258 0.0271 0.0252
Plasmodium falciparum calcium-dependent protein kinase 2 0.028 0.0318 0.3538
Echinococcus granulosus MAP kinase activated protein kinase 2 0.1302 0.2558 0.2537

Activities

Activity type Activity value Assay description Source Reference
Potency (functional) 0.92 uM PubChem BioAssay. A quantitative high throughput screen for small molecules that induce DNA re-replication in MCF 10a normal breast cells. (Class of assay: confirmatory) ChEMBL. No reference
Potency (functional) 4.6535 uM PUBCHEM_BIOASSAY: Primary qHTS for delayed death inhibitors of the malarial parasite plastid, 96 hour incubation. (Class of assay: confirmatory) [Related pubchem assays (depositor defined):AID488745, AID488752, AID488774, AID504848, AID504850] ChEMBL. No reference
Potency (functional) 7.9433 uM PubChem BioAssay. qHTS of alpha-syn Inhibitors. (Class of assay: confirmatory) ChEMBL. No reference
Potency (functional) 8.9125 uM PubChem BioAssay. qHTS of GLP-1 Receptor Inverse Agonists (Inhibition Mode). (Class of assay: confirmatory) ChEMBL. No reference
Potency (functional) 18.526 uM PUBCHEM_BIOASSAY: Primary qHTS for delayed death inhibitors of the malarial parasite plastid, 48 hour incubation. (Class of assay: confirmatory) [Related pubchem assays (depositor defined):AID488752, AID488774, AID504848, AID504850] ChEMBL. No reference
Potency (functional) 23.0999 uM PUBCHEM_BIOASSAY: qHTS screen for small molecules that inhibit ELG1-dependent DNA repair in human embryonic kidney (HEK293T) cells expressing luciferase-tagged ELG1. (Class of assay: confirmatory) [Related pubchem assays (depositor defined):AID493107, AID493125] ChEMBL. No reference
Potency (functional) 25.1189 uM PUBCHEM_BIOASSAY: qHTS for Inhibitors of TGF-b. (Class of assay: confirmatory) [Related pubchem assays (depositor defined):AID588856, AID588860] ChEMBL. No reference
Potency (functional) = 25.1189 um PUBCHEM_BIOASSAY: qHTS Assay for Small Molecule Inhibitors of Mitochondrial Division or Activators of Mitochondrial Fusion. (Class of assay: confirmatory) ChEMBL. No reference
Potency (functional) 89.1251 uM PUBCHEM_BIOASSAY: HTS for Inhibitors of HP1-beta Chromodomain Interactions with Methylated Histone Tails. (Class of assay: confirmatory) [Related pubchem assays (depositor defined):AID488962] ChEMBL. No reference

Phenotypes

Whole-cell/tissue/organism interactions

Species name Source Reference Is orphan
Plasmodium falciparum ChEMBL23

Many chemical entities in TDR Targets come from high-throughput screenings with whole cells or tissue samples, and not all assayed compounds have been tested against a single a single target protein, probably because they get ruled out during screening process. Even if these compounds may have not been of interest in the original screening, they may come as interesting leads for other screening assays. Furthermore, we may be able to propose drug-target associations using chemical similarities and network patterns.

Annotated phenotypes:

We have no manually annotated phenotypes for this drug. What does this mean? / Care to help?
In TDR Targets, information about phenotypes that are caused by drugs, or by genetic manipulation of cells (e.g. gene knockouts or knockdowns) is manually curated from the literature. These descriptions help to describe the potential of the target for drug development. If no information is available for this gene or if the information is incomplete, this may mean that i) the papers containing this information either appeared after the curation effort for this organism was carried out or they were inadvertently missed by curators; or that ii) the curation effort for this organism has not yet started.
 
In any case, if you have information about papers containing relevant validation data for this target, please log in using your TDR Targets username and password and send them to us using the corresponding form in this page (only visible to registered users) or contact us.

External resources for this compound

Bibliographic References

No literature references available for this target.

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