Detailed information for compound 1351202

Basic information

Technical information
  • TDR Targets ID: 1351202
  • Name: 2-fluoro-N-(heptan-4-ylideneamino)benzamide
  • MW: 250.312 | Formula: C14H19FN2O
  • H donors: 1 H acceptors: 1 LogP: 3.15 Rotable bonds: 7
    Rule of 5 violations (Lipinski): 1
  • SMILES: CCCC(=NNC(=O)c1ccccc1F)CCC
  • InChi: 1S/C14H19FN2O/c1-3-7-11(8-4-2)16-17-14(18)12-9-5-6-10-13(12)15/h5-6,9-10H,3-4,7-8H2,1-2H3,(H,17,18)
  • InChiKey: WESCMZRFAFQOKQ-UHFFFAOYSA-N  


Substructure search Similarity search

Network

Hover on a compound node to display the structore

Synonyms

  • 2-fluoro-N-(1-propylbutylideneamino)benzamide
  • ZINC05018821
  • MLS001003660
  • SMR000347490
  • T0509-7967

Targets

Known targets for this compound

No curated genes were found associated with this compound

Predicted pathogen targets for this compound

By orthology
No druggable targets predicted by orthology data
By sequence similarity to non orthologous known druggable targets
No druggable targets predicted by sequence similarity
Obtained from network model

Ranking Plot

Putative Targets List

Species Potential target Raw Global Species
Echinococcus multilocularis leucine rich repeat serine:threonine protein 0.0149 0.0032 0.0026
Schistosoma mansoni protein kinase 0.0709 0.1627 0.3802
Loa Loa (eye worm) TK/EPH protein kinase 0.0377 0.0682 0.0826
Loa Loa (eye worm) hypothetical protein 0.0159 0.0061 0.0059
Echinococcus granulosus dual specificity testis-specific protein kinase 0.0701 0.1606 0.1595
Echinococcus granulosus insulin growth factor 1 receptor beta 0.1329 0.3392 0.3383
Loa Loa (eye worm) hypothetical protein 0.0351 0.0608 0.0735
Loa Loa (eye worm) SRC-1 0.0494 0.1017 0.124
Echinococcus multilocularis cGMP dependent protein kinase 1 0.0203 0.0187 0.0236
Entamoeba histolytica serine/threonine protein kinase STE20, putative 0.0254 0.0332 0.1006
Echinococcus multilocularis tyrosine protein kinase Fyn 0.0494 0.1017 0.1368
Echinococcus granulosus serine:threonine protein kinase MARK2 0.043 0.0832 0.082
Trichomonas vaginalis AGC family protein kinase 0.016 0.0065 0.0198
Echinococcus granulosus calcium activated potassium channel 0.0262 0.0354 0.0341
Toxoplasma gondii NIMA-related protein kinase NIMA1 0.0418 0.0798 0.2528
Echinococcus granulosus serine threonine protein kinase nrc 0.0696 0.1591 0.158
Trichomonas vaginalis conserved hypothetical protein 0.0169 0.009 0.0272
Trypanosoma cruzi cdc2-related kinase 1 0.0449 0.0886 0.4753
Echinococcus granulosus cyclin dependent kinase 9 0.0142 0.0014 0.0001
Echinococcus multilocularis dual specificity 0.0208 0.0201 0.0255
Brugia malayi Protein kinase domain containing protein 0.0151 0.0037 0.003
Trichomonas vaginalis CAMK family protein kinase 0.0222 0.024 0.0728
Loa Loa (eye worm) TKL/LRRK protein kinase 0.0149 0.0032 0.0023
Echinococcus granulosus epidermal growth factor receptor 0.1632 0.4256 0.4248
Echinococcus multilocularis tyrosine protein kinase Fyn 0.0494 0.1017 0.1368
Entamoeba histolytica protein kinase, putative 0.0504 0.1044 0.3167
Echinococcus granulosus calcium:calmodulin dependent protein kinase 0.0696 0.1591 0.158
Loa Loa (eye worm) TK/FER protein kinase 0.022 0.0236 0.0276
Echinococcus granulosus mitogen activated protein kinase kinase kinase 0.0783 0.1839 0.1828
Leishmania major cell division related protein kinase 2,cdc2-related kinase 0.0449 0.0886 0.4753
Toxoplasma gondii cell-cycle-associated protein kinase CDK, putative 0.0449 0.0886 0.2805
Trichomonas vaginalis CMGC family protein kinase 0.0438 0.0855 0.2593
Trypanosoma cruzi mitogen-activated protein kinase 11, putative 0.0302 0.0468 0.2511
Trichomonas vaginalis CAMK family protein kinase 0.0222 0.024 0.0728
Echinococcus multilocularis serine:threonine protein kinase MARK2 0.043 0.0832 0.1117
Schistosoma mansoni tyrosine kinase 0.1313 0.3348 0.7861
Echinococcus multilocularis casein kinase I alpha 0.029 0.0435 0.0574
Echinococcus multilocularis titin 0.0174 0.0104 0.0124
Echinococcus multilocularis roundabout 2 0.0436 0.085 0.114
Echinococcus granulosus serine:threonine protein kinase PAK 4 0.0624 0.1384 0.1372
Brugia malayi serine/threonine-protein kinase plk-2 0.0792 0.1864 0.2287
Echinococcus multilocularis cAMP dependent protein kinase catalytic subunit 0.0422 0.081 0.1086
Entamoeba histolytica protein kinase domain containing protein 0.0438 0.0855 0.2593
Plasmodium falciparum serine/threonine protein kinase KIN 0.0222 0.024 0.1507
Loa Loa (eye worm) hypothetical protein 0.0172 0.0099 0.0106
Echinococcus multilocularis calcium:calmodulin dependent protein kinase type 0.0225 0.0249 0.0321
Loa Loa (eye worm) protein kinase domain-containing protein 0.0291 0.0437 0.0524
Trichomonas vaginalis CAMK family protein kinase 0.0222 0.024 0.0728
Brugia malayi hypothetical protein 0.0309 0.0489 0.0587
Schistosoma mansoni serine/threonine protein kinase 0.0504 0.1044 0.2428
Loa Loa (eye worm) AGC/PDK1 protein kinase 0.0252 0.0325 0.0386
Echinococcus multilocularis serine:threonine protein kinase N2 0.0915 0.2213 0.2998
Trichomonas vaginalis CMGC family protein kinase 0.0208 0.0201 0.0609
Trichomonas vaginalis AGC family protein kinase 0.016 0.0065 0.0198
Echinococcus granulosus ribosomal protein S6 kinase alpha 3 0.0992 0.2432 0.2422
Trypanosoma cruzi cAMP-dependent protein kinase catalytic subunit 2 0.0422 0.081 0.4345
Trichomonas vaginalis CAMK family protein kinase 0.08 0.1886 0.5724
Plasmodium vivax serine/threonine protein kinase 6, putative 0.0504 0.1044 0.6558
Loa Loa (eye worm) TK/FER protein kinase 0.022 0.0236 0.0276
Schistosoma mansoni diacylglycerol kinase theta 0.0152 0.0043 0.0069
Loa Loa (eye worm) TK/FER protein kinase 0.022 0.0236 0.0276
Loa Loa (eye worm) hypothetical protein 0.0223 0.0244 0.0285
Loa Loa (eye worm) IKK protein kinase 0.1015 0.2499 0.3073
Trichomonas vaginalis ribosomal protein S6 kinase, 90kD, polypeptide, putative 0.016 0.0065 0.0198
Echinococcus granulosus aurora kinase A 0.0504 0.1044 0.1032
Loa Loa (eye worm) hypothetical protein 0.0724 0.167 0.2047
Brugia malayi protein kinase C3,putative 0.0506 0.1049 0.128
Echinococcus granulosus casein kinase I alpha 0.029 0.0435 0.0422
Trichomonas vaginalis CMGC family protein kinase 0.0438 0.0855 0.2593
Loa Loa (eye worm) calcium/calmodulin-dependent protein kinase subunit type II alpha 0.0484 0.0986 0.1203
Entamoeba histolytica protein kinase domain containing protein 0.0437 0.0853 0.2588
Brugia malayi RhoGAP domain containing protein 0.0256 0.0337 0.04
Echinococcus multilocularis CDC7 cell division cycle 7 0.0153 0.0044 0.0042
Brugia malayi Serine/threonine-protein kinase SULU 0.0491 0.1005 0.1226
Schistosoma mansoni protein kinase 0.0701 0.1606 0.3754
Schistosoma mansoni serine/threonine protein kinase 0.0153 0.0044 0.0072
Loa Loa (eye worm) hypothetical protein 0.0421 0.0806 0.098
Echinococcus multilocularis cGMP dependent protein kinase 1 0.0203 0.0187 0.0236
Leishmania major rac serine-threonine kinase, putative,protein kinase, putative 0.0489 0.1002 0.5378
Loa Loa (eye worm) hypothetical protein 0.0152 0.0043 0.0036
Brugia malayi SH2 domain containing protein 0.022 0.0236 0.0276
Trichomonas vaginalis CMGC family protein kinase 0.0345 0.0591 0.1795
Schistosoma mansoni serine/threonine protein kinase 0.124 0.3138 0.7366
Entamoeba histolytica protein kinase domain containing protein 0.0437 0.0853 0.2588
Echinococcus multilocularis 5' AMP activated protein kinase catalytic 0.0625 0.1389 0.1875
Entamoeba histolytica serine/threonine- protein kinase 6 , putative 0.0504 0.1044 0.3167
Echinococcus multilocularis RNA directed DNA polymerase 0.0166 0.0081 0.0092
Echinococcus granulosus serine:threonine protein kinase 3 0.0802 0.1893 0.1882
Schistosoma mansoni serine/threonine protein kinase 0.0422 0.081 0.1877
Brugia malayi Protein kinase domain containing protein 0.0373 0.0672 0.0814
Echinococcus granulosus maternal embryonic leucine zipper kinase 0.0181 0.0125 0.0111
Echinococcus granulosus cyclin dependent kinase 19 0.0221 0.0237 0.0223
Trichomonas vaginalis CMGC family protein kinase 0.0438 0.0855 0.2593
Brugia malayi hypothetical protein 0.0223 0.0244 0.0285
Echinococcus granulosus cyclin dependent kinase 1 0.0449 0.0886 0.0874
Plasmodium falciparum casein kinase 1 0.029 0.0435 0.2731
Toxoplasma gondii cell-cycle-associated protein kinase GSK, putative 0.0437 0.0853 0.2701
Echinococcus multilocularis casein kinase I alpha 0.029 0.0435 0.0574
Echinococcus multilocularis casein kinase I alpha 0.029 0.0435 0.0574
Brugia malayi Sex muscle abnormal protein 5 0.0188 0.0145 0.0163
Schistosoma mansoni serine/threonine protein kinase 0.102 0.2512 0.589
Schistosoma mansoni serine/threonine protein kinase 0.0236 0.0281 0.063
Loa Loa (eye worm) hypothetical protein 0.0309 0.0489 0.0587
Trypanosoma brucei mitogen-activated protein kinase kinase 5 0.0238 0.0286 0.0867
Brugia malayi casein kinase 1, delta 0.029 0.0435 0.0521
Trypanosoma cruzi glycogen synthase kinase 3, putative 0.0437 0.0853 0.4577
Leishmania major serine/threonine-protein kinase, putative,protein kinase, putative 0.0145 0.0023 0.0122
Plasmodium falciparum protein kinase, putative 0.0206 0.0196 0.1233
Plasmodium falciparum protein kinase 5 0.0449 0.0886 0.5567
Loa Loa (eye worm) CAMK/CAMKL/MARK protein kinase 0.0258 0.0342 0.0406
Echinococcus multilocularis mitogen activated protein kinase kinase kinase 0.0783 0.1839 0.2488
Schistosoma mansoni ste20-related kinase 0.0638 0.1424 0.3325
Loa Loa (eye worm) hypothetical protein 0.039 0.0718 0.0871
Echinococcus granulosus raf serine:threonine protein kinase 0.027 0.0376 0.0363
Loa Loa (eye worm) casein kinase 0.0202 0.0183 0.021
Schistosoma mansoni tyrosine kinase 0.1103 0.2748 0.6446
Loa Loa (eye worm) CAMK/CAMKL/AMPK protein kinase 0.0625 0.1389 0.17
Echinococcus granulosus tyrosine protein kinase shark 0.022 0.0236 0.0223
Leishmania major protein kinase, putative,polo-like protein kinase, putative 0.0792 0.1864 1
Trichomonas vaginalis CMGC family protein kinase 0.0208 0.0201 0.0609
Trichomonas vaginalis AGC family protein kinase 0.0504 0.1044 0.3167
Echinococcus granulosus [G-protein-coupledreceptor] kinase 0.0205 0.0192 0.0179
Entamoeba histolytica serine/threonine protein kinase, putative 0.0792 0.1864 0.5656
Toxoplasma gondii Tyrosine kinase-like (TKL) protein 0.0143 0.0016 0.0051
Entamoeba histolytica protein kinase domain containing protein 0.0279 0.0404 0.1225
Brugia malayi Doublecortin family protein 0.0221 0.0239 0.0278
Trichomonas vaginalis AGC family protein kinase 0.0252 0.0325 0.0987
Echinococcus granulosus casein kinase ii subunit alpha 0.0438 0.0855 0.0842
Loa Loa (eye worm) AGC/PKC/IOTA protein kinase 0.0525 0.1104 0.1348
Toxoplasma gondii calcium-dependent protein kinase CDPK2B 0.0225 0.0249 0.0787
Trichomonas vaginalis AGC family protein kinase 0.016 0.0065 0.0198
Trypanosoma brucei CMGC/DYRK protein kinase, putative 0.0552 0.1181 0.3585
Loa Loa (eye worm) AGC/PKN protein kinase 0.0915 0.2213 0.2718
Echinococcus multilocularis tyrosine protein kinase shark 0.022 0.0236 0.0304
Echinococcus granulosus hypothetical protein 0.0256 0.0337 0.0324
Echinococcus granulosus TGF beta receptor type 1 0.0161 0.0067 0.0054
Echinococcus multilocularis Rac GTPase activating protein 1 0.0152 0.0043 0.004
Schistosoma mansoni protein kinase 0.0268 0.0372 0.0846
Loa Loa (eye worm) hypothetical protein 0.0418 0.0798 0.097
Trypanosoma cruzi STE/STE11 serine/threonine-protein kinase, putative 0.0206 0.0196 0.1053
Echinococcus multilocularis sodium:potassium dependent atpase beta subunit 0.0607 0.1337 0.1804
Trichomonas vaginalis AGC family protein kinase 0.016 0.0065 0.0198
Echinococcus granulosus calcium:calmodulin dependent protein kinase type 1 0.0225 0.0249 0.0236
Echinococcus granulosus activated cdc42 kinase 1 0.0283 0.0415 0.0402
Schistosoma mansoni tyrosine kinase 0.0804 0.1897 0.444
Trypanosoma brucei SNF1-related protein kinases, putative 0.0222 0.024 0.0728
Giardia lamblia Kinase, CMGC CK2 0.0438 0.0855 0.4518
Echinococcus multilocularis calcium activated potassium channel 0.0262 0.0354 0.0464
Leishmania major protein kinase, putative,dual-specificity protein kinase, putative 0.0208 0.0201 0.1077
Echinococcus multilocularis Serine:threonine protein kinase PLK4 0.0322 0.0525 0.0698
Leishmania major mitogen-activated protein kinase kinase 5, putative;with=GeneDB:LmxM36.0860 0.0238 0.0286 0.1533
Trichomonas vaginalis AGC family protein kinase 0.1295 0.3295 1
Echinococcus multilocularis dual specificity 0.0552 0.1181 0.1592
Brugia malayi C1-like domain containing protein 0.0631 0.1407 0.1722
Echinococcus granulosus casein kinase I gamma 0.0291 0.0437 0.0425
Echinococcus multilocularis cAMP dependent protein kinase catalytic subunit 0.0422 0.081 0.1086
Trichomonas vaginalis AGC family protein kinase 0.0711 0.1632 0.4953
Schistosoma mansoni serine/threonine-protein kinase 0.0744 0.1728 0.4042
Loa Loa (eye worm) TK/FAK protein kinase 0.0373 0.0672 0.0814
Giardia lamblia Kinase, NEK 0.0418 0.0798 0.4214
Leishmania major casein kinase II, putative 0.0438 0.0855 0.4585
Schistosoma mansoni serine/threonine protein kinase 0.0158 0.006 0.0109
Echinococcus granulosus 5' AMP activated protein kinase catalytic 0.0625 0.1389 0.1377
Brugia malayi RhoGAP domain containing protein 0.0152 0.0043 0.0036
Entamoeba histolytica protein kinase domain containing protein 0.0552 0.1181 0.3585
Echinococcus multilocularis Ribosomal protein S6 kinase beta 2 0.064 0.143 0.1931
Leishmania major serine/threonine-protein kinase, putative,protein kinase, putative 0.0552 0.1181 0.6338
Schistosoma mansoni chimerin-related rho-gtpase-activating protein 0.0256 0.0337 0.0763
Trichomonas vaginalis CMGC family protein kinase 0.0438 0.0855 0.2593
Entamoeba histolytica diacylglycerol kinase, putative 0.0152 0.0043 0.0129
Plasmodium falciparum glycogen synthase kinase 3 0.0437 0.0853 0.5361
Leishmania major serine/threonine protein kinase, putative,protein kinase, putative 0.0222 0.024 0.1287
Echinococcus granulosus nervana 2 0.0607 0.1337 0.1325
Echinococcus multilocularis serine:threonine protein kinase PAK 3 0.0258 0.0344 0.0451
Trypanosoma cruzi serine/arginine-rich protein specific kinase SRPK, putative 0.0145 0.0023 0.0122
Schistosoma mansoni protein kinase 0.0504 0.1044 0.2428
Plasmodium vivax calcium-dependent protein kinase, putative 0.0225 0.0249 0.1562
Brugia malayi Immunoglobulin I-set domain containing protein 0.0309 0.0489 0.0587
Echinococcus granulosus dual specificity protein kinase clk2 0.0345 0.0591 0.0579
Schistosoma mansoni tyrosine kinase 0.0181 0.0124 0.0261
Brugia malayi Immunoglobulin I-set domain containing protein 0.0822 0.1949 0.2392
Echinococcus granulosus titin 0.0174 0.0104 0.0091
Schistosoma mansoni protein kinase 0.0189 0.0146 0.0314
Toxoplasma gondii AGC kinase 0.0422 0.081 0.2564
Trichomonas vaginalis CMGC family protein kinase 0.0302 0.0468 0.142
Echinococcus multilocularis casein kinase I delta 0.029 0.0435 0.0574
Loa Loa (eye worm) hypothetical protein 0.0169 0.009 0.0094
Brugia malayi Protein kinase domain containing protein 0.022 0.0236 0.0276
Schistosoma mansoni serine/threonine protein kinase 0.0145 0.0023 0.0022
Loa Loa (eye worm) AGC/AKT protein kinase 0.1295 0.3295 0.4056
Trichomonas vaginalis AGC family protein kinase 0.016 0.0065 0.0198
Echinococcus granulosus Serine/threonine-protein kinase Genghis Khan 0.0619 0.1372 0.136
Trypanosoma cruzi mitogen-activated protein kinase 3, putative 0.0617 0.1366 0.7331
Trichomonas vaginalis AGC family protein kinase 0.016 0.0065 0.0198
Echinococcus granulosus serine:threonine protein kinase N2 0.0915 0.2213 0.2202
Loa Loa (eye worm) hypothetical protein 0.0463 0.0927 0.1129
Loa Loa (eye worm) hypothetical protein 0.0249 0.0317 0.0376
Loa Loa (eye worm) TKL/STKR/TYPE1 protein kinase 0.0151 0.0037 0.003
Brugia malayi Protein kinase domain containing protein 0.0258 0.0342 0.0406
Entamoeba histolytica protein kinase, putative 0.1295 0.3295 1
Trichomonas vaginalis CMGC family protein kinase 0.0153 0.0044 0.0133
Loa Loa (eye worm) AGC/PDK1 protein kinase 0.0244 0.0303 0.0358
Plasmodium falciparum cAMP-dependent protein kinase catalytic subunit 0.0422 0.081 0.5089
Entamoeba histolytica SH2-protein kinase domain containing protein 0.022 0.0236 0.0717
Trichomonas vaginalis CAMK family protein kinase 0.0222 0.024 0.0728
Schistosoma mansoni serine/threonine protein kinase 0.0291 0.0437 0.1
Loa Loa (eye worm) CAMK/PKD protein kinase 0.0479 0.0972 0.1185
Trichomonas vaginalis CMGC family protein kinase 0.0153 0.0044 0.0133
Echinococcus multilocularis tyrosine protein kinase Src42A 0.0296 0.0452 0.0598
Loa Loa (eye worm) CAMK protein kinase 0.0174 0.0104 0.0112
Trichomonas vaginalis CAMK family protein kinase 0.0792 0.1864 0.5656
Echinococcus granulosus myotubularin protein 13 0.0201 0.018 0.0167
Schistosoma mansoni ephrin receptor 0.0321 0.0522 0.12
Loa Loa (eye worm) CDC7 protein kinase 0.0153 0.0044 0.0038
Brugia malayi Variant SH3 domain containing protein 0.0158 0.0059 0.0056
Schistosoma mansoni hypothetical protein 0.0152 0.0043 0.0069
Echinococcus granulosus Serine:threonine protein kinase PLK4 0.0322 0.0525 0.0513
Schistosoma mansoni tyrosine kinase 0.0305 0.0478 0.1096
Leishmania major protein kinase A catalytic subunit isoform 2 0.0422 0.081 0.4345
Echinococcus granulosus serine:threonine protein kinase mig 15 0.0418 0.0798 0.0786
Toxoplasma gondii AGC kinase 0.1247 0.3158 1
Loa Loa (eye worm) AGC/GRK/GRK protein kinase 0.0205 0.0192 0.0221
Echinococcus multilocularis protein kinase c iota type 0.1056 0.2616 0.3547
Loa Loa (eye worm) STE/STE20/PAKA protein kinase 0.0158 0.006 0.0057
Trichomonas vaginalis serine/threonine-protein kinase sgk, putative 0.0573 0.1241 0.3765
Toxoplasma gondii cell-cycle-associated protein kinase DYRK2, putative 0.0208 0.0201 0.0636
Brugia malayi ribosomal protein S6 kinase alpha 3 0.0441 0.0865 0.1053
Schistosoma mansoni serine/threonine protein kinase 0.0222 0.024 0.0534
Echinococcus multilocularis death associated protein kinase 1 0.2718 0.7349 1
Trypanosoma cruzi cdc2-related kinase 3 0.0449 0.0886 0.4753
Loa Loa (eye worm) hypothetical protein 0.0294 0.0445 0.0533
Entamoeba histolytica hypothetical protein 0.0425 0.082 0.2488
Echinococcus multilocularis activin receptor type 0.0573 0.1241 0.1673
Trichomonas vaginalis AGC family protein kinase 0.016 0.0065 0.0198
Schistosoma mansoni unc-13 (munc13) 0.0159 0.0061 0.0113
Schistosoma mansoni hypothetical protein 0.0223 0.0244 0.0544
Echinococcus multilocularis epidermal growth factor receptor 0.1103 0.2748 0.3728
Trypanosoma cruzi Protein kinase B 0.0744 0.1728 0.9273
Trypanosoma brucei calcium/calmodulin-dependent protein kinase, putative 0.0225 0.0249 0.0754
Loa Loa (eye worm) TK protein kinase 0.0306 0.048 0.0577
Loa Loa (eye worm) AGC/GRK/GRK protein kinase 0.0218 0.0229 0.0267
Onchocerca volvulus 0.072 0.1658 0.37
Brugia malayi Protein kinase domain containing protein 0.0897 0.2161 0.2655
Plasmodium falciparum calcium-dependent protein kinase 4 0.0225 0.0249 0.1562
Echinococcus granulosus ribosomal protein s6 kinase beta 1 0.064 0.143 0.1418
Echinococcus granulosus tyrosine protein kinase Btk29A 0.0885 0.2128 0.2117
Plasmodium vivax protein kinase, putative 0.0144 0.002 0.0123
Trypanosoma cruzi rac serine-threonine kinase, putative 0.0744 0.1728 0.9273
Echinococcus multilocularis protein kinase c eta type 0.0152 0.0043 0.004
Loa Loa (eye worm) CMGC/MAPK/P38 protein kinase 0.0617 0.1366 0.1672
Trichomonas vaginalis STE family protein kinase 0.0258 0.0344 0.1044
Toxoplasma gondii calcium dependent protein kinase CDPK8 0.0206 0.0196 0.0621
Entamoeba histolytica protein kinase, putative 0.0306 0.048 0.1457
Echinococcus multilocularis serine:threonine protein kinase 38 0.064 0.143 0.1931
Echinococcus granulosus c src tyrosine kinase 0.0305 0.0478 0.0465
Echinococcus granulosus Ribosomal protein S6 kinase beta 2 0.064 0.143 0.1418
Loa Loa (eye worm) TK/INSR protein kinase 0.1313 0.3348 0.4122
Entamoeba histolytica PH domain containing protein kinase, putative 0.0744 0.1728 0.5245
Loa Loa (eye worm) immunoglobulin I-set domain-containing protein 0.0163 0.0072 0.0072
Schistosoma mansoni tyrosine kinase 0.0244 0.0303 0.0683
Brugia malayi Variant SH3 domain containing protein 0.0256 0.0337 0.04
Schistosoma mansoni serine/threonine protein kinase 0.0422 0.081 0.1877
Echinococcus granulosus casein kinase I delta 0.029 0.0435 0.0422
Schistosoma mansoni serine/threonine protein kinase 0.0758 0.1767 0.4134
Brugia malayi Protein kinase domain containing protein 0.0621 0.1376 0.1684
Schistosoma mansoni defective proboscis extension response (dpr)-related 0.0294 0.0445 0.1017
Echinococcus granulosus protein kinase c iota type 0.1056 0.2616 0.2606
Loa Loa (eye worm) hypothetical protein 0.0379 0.0687 0.0833
Entamoeba histolytica protein kinase, putative 0.1295 0.3295 1
Echinococcus multilocularis casein kinase i 0.029 0.0435 0.0574
Echinococcus granulosus c-Jun N-terminal kinases 0.1057 0.2619 0.2609
Schistosoma mansoni titin 0.0174 0.0104 0.0215
Echinococcus granulosus serine/threonine protein kinase 0.0744 0.1728 0.1717
Brugia malayi Protein kinase domain 0.0258 0.0344 0.0409
Entamoeba histolytica protein kinase, putative 0.1247 0.3158 0.9584
Echinococcus granulosus mitogen activated protein kinase kinase kinase 0.0312 0.0498 0.0486
Schistosoma mansoni serine/threonine protein kinase 0.0225 0.0249 0.0554
Loa Loa (eye worm) hypothetical protein 0.0421 0.0806 0.098
Echinococcus multilocularis p21 activated protein kinase 1 Dpak1 0.0258 0.0344 0.0451
Plasmodium falciparum calcium-dependent protein kinase 2 0.0225 0.0249 0.1562
Loa Loa (eye worm) TK/FER protein kinase 0.022 0.0236 0.0276
Brugia malayi Calcium/calmodulin-dependent protein kinase type II alpha chain 0.0225 0.0249 0.0291
Onchocerca volvulus 0.093 0.2258 0.5075
Schistosoma mansoni tyrosine kinase 0.0217 0.0226 0.0502
Entamoeba histolytica SH2-protein kinase domain containing protein 0.0193 0.0157 0.0477
Brugia malayi Protein kinase domain containing protein 0.0577 0.1252 0.1531
Schistosoma mansoni serine/threonine protein kinase 0.0422 0.081 0.1877
Loa Loa (eye worm) CAMK/MLCK protein kinase 0.0231 0.0268 0.0314
Echinococcus multilocularis cAMP dependent protein kinase catalytic subunit 0.0422 0.081 0.1086
Echinococcus granulosus cAMP dependent protein kinase catalytic subunit 0.0422 0.081 0.0797
Loa Loa (eye worm) hypothetical protein 0.022 0.0236 0.0276
Echinococcus multilocularis cyclin dependent kinase 9 0.0142 0.0014 0.0001
Echinococcus granulosus neurotracting:lsamp:neurotrimin:obcam 0.0351 0.0608 0.0596
Echinococcus multilocularis protein kinase shaggy 0.0437 0.0853 0.1145
Echinococcus multilocularis activated cdc42 kinase 1 0.0283 0.0415 0.0548
Trichomonas vaginalis AGC family protein kinase 0.1295 0.3295 1
Entamoeba histolytica protein kinase, putative 0.0552 0.1181 0.3585
Loa Loa (eye worm) CMGC/DYRK/DYRK1 protein kinase 0.0552 0.1181 0.1443
Trichomonas vaginalis AGC family protein kinase 0.016 0.0065 0.0198
Brugia malayi Protein kinase domain containing protein 0.064 0.143 0.1751
Loa Loa (eye worm) TK/FER protein kinase 0.022 0.0236 0.0276
Echinococcus granulosus casein kinase I delta 0.029 0.0435 0.0422
Loa Loa (eye worm) AGC/NDR protein kinase 0.064 0.143 0.1751
Entamoeba histolytica casein kinase, putative 0.029 0.0435 0.1319
Brugia malayi Protein kinase domain containing protein 0.0449 0.0886 0.1078
Brugia malayi Protein kinase domain containing protein 0.0145 0.0023 0.0012
Brugia malayi Probable G protein-coupled receptor kinase F19C6.1, putative 0.0205 0.0192 0.0221
Echinococcus granulosus 3-phosphoinositide-dependent protein kinase 1 0.0244 0.0303 0.029
Echinococcus multilocularis tyrosine protein kinase HCK 0.0306 0.048 0.0636
Loa Loa (eye worm) CMGC/DYRK/HIPK protein kinase 0.0279 0.0404 0.0482
Schistosoma mansoni serine/threonine protein kinase 0.0244 0.0303 0.0682
Schistosoma mansoni cell adhesion molecule 0.0366 0.0652 0.1505
Entamoeba histolytica protein kinase, putative 0.0237 0.0284 0.0863
Leishmania major glycogen synthase kinase, putative;with=GeneDB:LinJ18_V3.0270 0.0437 0.0853 0.4577
Entamoeba histolytica PH domain containing protein kinase, putative 0.047 0.0947 0.2873
Echinococcus granulosus 5'partial|cyclin dependent kinase 1 0.0449 0.0886 0.0874
Schistosoma mansoni tyrosine kinase 0.1632 0.4256 1
Trypanosoma cruzi Vacuolar sorting protein 39 domain 1/Vacuolar sorting protein 39 domain 2, putative 0.0223 0.0244 0.1309
Entamoeba histolytica serine/threonine protein kinase 6, putative 0.0504 0.1044 0.3167
Loa Loa (eye worm) TK/ROR protein kinase 0.0187 0.014 0.0156
Loa Loa (eye worm) hypothetical protein 0.0225 0.0249 0.0291
Plasmodium vivax NIMA-related protein kinase (Pfnek-1), putative 0.0418 0.0798 0.5018
Leishmania major protein kinase, putative 0.0225 0.0249 0.1334
Loa Loa (eye worm) CAMK/PIM protein kinase 0.0758 0.1767 0.2168
Echinococcus granulosus N chimaerin 0.0256 0.0337 0.0324
Leishmania major protein kinase A catalytic subunit 0.0422 0.081 0.4345
Echinococcus multilocularis tyrosine kinase 0.022 0.0236 0.0304
Echinococcus granulosus defective proboscis extension response 0.0294 0.0445 0.0432
Trypanosoma cruzi dual specificity tyrosine-phosphorylation-regulated kinase 2, putative 0.0208 0.0201 0.1077
Onchocerca volvulus 0.1498 0.3875 0.8782
Schistosoma mansoni tyrosine kinase 0.0752 0.1751 0.4095
Echinococcus multilocularis serine:threonine protein kinase 3 0.0802 0.1893 0.2562
Leishmania major casein kinase, putative 0.029 0.0435 0.2332
Giardia lamblia Kinase, AGC AKT 0.0441 0.0865 0.4576
Brugia malayi Variant SH3 domain containing protein 0.0188 0.0145 0.0163
Brugia malayi P38 map kinase family protein 2 0.0617 0.1366 0.1672
Schistosoma mansoni tyrosine kinase 0.0554 0.1185 0.2762
Echinococcus granulosus cGMP dependent protein kinase 1 0.0203 0.0187 0.0174
Trichomonas vaginalis STE family protein kinase 0.0254 0.0332 0.1006
Echinococcus multilocularis Protein kinase C, brain isozyme 0.0965 0.2355 0.3192
Echinococcus granulosus serine:threonine protein kinase TAO1 0.0491 0.1005 0.0993
Loa Loa (eye worm) AGC/PKC/ALPHA protein kinase 0.0262 0.0354 0.0421
Schistosoma mansoni protein kinase 0.0438 0.0855 0.1983
Trichomonas vaginalis CMGC family protein kinase 0.0449 0.0886 0.2688
Echinococcus granulosus leucine rich repeat serine:threonine protein 0.0148 0.003 0.0017
Trichomonas vaginalis AGC family protein kinase 0.0504 0.1044 0.3167
Echinococcus granulosus tyrosine protein kinase Fps85D 0.0366 0.0651 0.0638
Echinococcus multilocularis mitogen activated protein kinase 11 0.0617 0.1366 0.1844
Echinococcus multilocularis guanine nucleotide exchange factor VAV2 0.0256 0.0337 0.0441
Schistosoma mansoni serine/threonine protein kinase 0.0449 0.0886 0.2057
Schistosoma mansoni protein kinase 0.029 0.0435 0.0993
Brugia malayi Protein kinase domain containing protein 0.0345 0.0591 0.0714
Trypanosoma cruzi STE/STE20 serine/threonine-protein kinase, putative 0.0254 0.0332 0.1779
Schistosoma mansoni protein kinase 0.0701 0.1606 0.3754
Loa Loa (eye worm) hypothetical protein 0.0222 0.024 0.028
Loa Loa (eye worm) hypothetical protein 0.072 0.1658 0.2032
Trichomonas vaginalis 3-phosphoinositide dependent protein kinase-1, putative 0.016 0.0065 0.0198
Trichomonas vaginalis AGC family protein kinase 0.1295 0.3295 1
Trypanosoma brucei polo-like protein kinase 0.0792 0.1864 0.5656
Schistosoma mansoni protein kinase 0.0189 0.0147 0.0316
Echinococcus multilocularis expressed conserved protein 0.0203 0.0187 0.0236
Brugia malayi Protein kinase domain containing protein 0.0149 0.0032 0.0023
Echinococcus multilocularis calcium:calmodulin dependent protein kinase I 0.021 0.0206 0.0263
Schistosoma mansoni serine/threonine protein kinase 0.0262 0.0354 0.0802
Echinococcus multilocularis myosin iiia 0.0254 0.0332 0.0434
Loa Loa (eye worm) RasGEF domain-containing protein 0.0152 0.0043 0.0036
Entamoeba histolytica protein kinase domain containing protein 0.0208 0.0201 0.0609
Toxoplasma gondii cell-cycle-associated protein kinase SRPK, putative 0.0145 0.0023 0.0072
Echinococcus multilocularis cyclin dependent kinase 1 0.0449 0.0886 0.1189
Brugia malayi Protein kinase domain containing protein 0.0724 0.167 0.2047
Onchocerca volvulus 0.0201 0.018 0.0312
Trichomonas vaginalis CAMK family protein kinase 0.0225 0.0249 0.0754
Echinococcus granulosus roundabout 2 0.0436 0.085 0.0838
Loa Loa (eye worm) camk/mapkapk/mnk protein kinase 0.0554 0.1187 0.1451
Echinococcus multilocularis serine:threonine protein kinase 0.0258 0.0342 0.0448
Schistosoma mansoni growth factor receptor-bound protein 0.0192 0.0156 0.0336
Echinococcus multilocularis GTPase activating Rap:RanGAP domain 3 0.0223 0.0244 0.0314
Echinococcus multilocularis 0.0464 0.0931 0.1251
Brugia malayi EST embl|AI107989|AI107989 comes from the 3' UTR, putative 0.0625 0.1389 0.17
Echinococcus granulosus tyrosine protein kinase Src42A 0.0494 0.1017 0.1005
Loa Loa (eye worm) hypothetical protein 0.0872 0.2092 0.2569
Brugia malayi Protein kinase domain containing protein 0.0792 0.1863 0.2285
Trichomonas vaginalis CAMK family protein kinase 0.0792 0.1864 0.5656
Trichomonas vaginalis AGC family protein kinase 0.016 0.0065 0.0198
Trypanosoma cruzi mitogen-activated protein kinase kinase 5 0.0238 0.0286 0.1533
Leishmania major protein kinase, putative 0.0345 0.0591 0.3173
Echinococcus granulosus cGMP dependent protein kinase 0.0203 0.0187 0.0174
Echinococcus multilocularis mitogen activated protein kinase kinase kinase 0.0312 0.0498 0.0661
Echinococcus granulosus MAP kinase activated protein kinase 2 0.124 0.3138 0.3129
Plasmodium vivax rac-beta serine/threonine protein kinase, putative 0.0696 0.1591 1
Entamoeba histolytica cell division protein kinase 2, putative 0.0456 0.0908 0.2757
Echinococcus multilocularis cyclin dependent kinase 5 0.0449 0.0886 0.1189
Trypanosoma brucei Vacuolar sorting protein 39 domain 1/Vacuolar sorting protein 39 domain 2, putative 0.0223 0.0244 0.074
Trypanosoma cruzi kinetoplastid kinetochore protein 10, putative 0.0345 0.0591 0.3173
Echinococcus multilocularis proto oncogene tyrosine protein kinase LCK 0.0494 0.1017 0.1368
Plasmodium vivax casein kinase 2, alpha subunit, putative 0.0438 0.0855 0.537
Trichomonas vaginalis AGC family protein kinase 0.016 0.0065 0.0198
Loa Loa (eye worm) hypothetical protein 0.059 0.1289 0.1577
Echinococcus granulosus serine:threonine protein kinase PAK 3 0.0258 0.0344 0.0331
Schistosoma mansoni protein kinase 0.0507 0.1053 0.245
Schistosoma mansoni protein kinase 0.0783 0.1839 0.4303
Schistosoma mansoni serine/threonine protein kinase 0.0619 0.1372 0.3202
Trichomonas vaginalis STE family protein kinase 0.0258 0.0344 0.1044
Echinococcus granulosus glycogen synthase kinase 3 beta 0.0437 0.0853 0.0841
Echinococcus granulosus ephrin type A receptor 4 A 0.0321 0.0522 0.051
Brugia malayi Protein kinase domain containing protein 0.1015 0.2499 0.3073
Echinococcus multilocularis c Jun NH2 terminal kinase 0.1057 0.2619 0.3552
Trypanosoma cruzi SNF1-related protein kinases, putative 0.0222 0.024 0.1287
Brugia malayi putative serine/threonine kinase SADA gamma 0.0222 0.024 0.028
Loa Loa (eye worm) TK/ALK protein kinase 0.0896 0.2161 0.2654
Trichomonas vaginalis CMGC family protein kinase 0.0302 0.0468 0.142
Loa Loa (eye worm) CMGC/CDK/CDK5 protein kinase 0.0449 0.0886 0.1078
Brugia malayi Immunoglobulin I-set domain containing protein 0.1966 0.5208 0.642
Entamoeba histolytica protein kinase, putative 0.0193 0.0157 0.0477
Trichomonas vaginalis CMGC family protein kinase 0.0302 0.0468 0.142
Schistosoma mansoni serine/threonine protein kinase 0.0915 0.2213 0.5184
Loa Loa (eye worm) AUR protein kinase 0.0504 0.1044 0.1273
Brugia malayi Egg laying defective protein 4 0.0203 0.0187 0.0214
Entamoeba histolytica protein kinase 2, putative 0.0696 0.1591 0.4829
Schistosoma mansoni serine/threonine protein kinase 0.0159 0.0061 0.0112
Plasmodium falciparum serine/threonine protein kinase 0.0145 0.0023 0.0143
Plasmodium falciparum calcium-dependent protein kinase 1 0.0225 0.0249 0.1562
Echinococcus granulosus titin 0.0174 0.0104 0.0091
Entamoeba histolytica p21-activated kinase 0.0306 0.0481 0.146
Trichomonas vaginalis AGC family protein kinase 0.0504 0.1044 0.3167
Schistosoma mansoni serine/threonine protein kinase 0.064 0.143 0.3339
Echinococcus multilocularis tyrosine protein kinase Fyn 0.041 0.0775 0.1038
Loa Loa (eye worm) RhoGAP domain-containing protein 0.0256 0.0337 0.04
Schistosoma mansoni serine/threonine protein kinase 0.0158 0.006 0.0109
Schistosoma mansoni mitogen-activated protein kinase kinase kinase 3 mapkkk3 mekk3 0.0223 0.0244 0.0544
Loa Loa (eye worm) hypothetical protein 0.0188 0.0145 0.0163
Echinococcus granulosus dual specificity 0.0208 0.0201 0.0188
Brugia malayi diacylglycerol kinase 0.0152 0.0043 0.0036
Echinococcus multilocularis 0.0256 0.0337 0.0441
Echinococcus granulosus p21 activated protein kinase 1 Dpak1 0.0258 0.0344 0.0331
Echinococcus multilocularis dual specificity testis specific protein kinase 0.0701 0.1606 0.2171
Giardia lamblia Kinase, AGC PKA 0.0422 0.081 0.4275
Schistosoma mansoni serine/threonine kinase 0.064 0.143 0.3339
Giardia lamblia Kinase, CMGC CDK 0.0449 0.0886 0.4688
Giardia lamblia Kinase, CMGC CLK 0.0345 0.0591 0.3089
Schistosoma mansoni proto-oncogene tyrosine-protein kinase src 0.0305 0.0478 0.1096
Schistosoma mansoni serine/threonine protein kinase 0.0449 0.0886 0.2057
Echinococcus multilocularis neuroglian 0.0363 0.0643 0.0858
Brugia malayi RhoGEF domain containing protein 0.0152 0.0043 0.0036
Trypanosoma brucei Casein kinase II 0.0438 0.0855 0.2593
Loa Loa (eye worm) hypothetical protein 0.0309 0.0489 0.0587
Brugia malayi Probable G protein-coupled receptor kinase F19C6.1, putative 0.0218 0.0229 0.0267
Plasmodium vivax protein kinase Crk2 0.0449 0.0886 0.5567
Loa Loa (eye worm) camk/dcamkl protein kinase 0.0221 0.0239 0.0278
Echinococcus granulosus casein kinase I alpha 0.029 0.0435 0.0422
Loa Loa (eye worm) variant SH3 domain-containing protein 0.0158 0.0059 0.0056
Schistosoma mansoni serine/threonine protein kinase 0.0221 0.0237 0.0526
Echinococcus granulosus C2 calcium dependent membrane targeting 0.0159 0.0061 0.0048
Loa Loa (eye worm) hypothetical protein 0.0295 0.0448 0.0537
Brugia malayi Protein kinase domain containing protein 0.0236 0.0281 0.0331
Entamoeba histolytica hypothetical protein 0.0152 0.0043 0.0129
Echinococcus multilocularis tyrosine protein kinase Fyn 0.0494 0.1017 0.1368
Trypanosoma brucei mitogen-activated protein kinase 3, putative 0.0617 0.1366 0.4146
Echinococcus granulosus tyrosine protein kinase Btk29A 0.0181 0.0124 0.0111
Echinococcus multilocularis tyrosine protein kinase ABL1 0.0657 0.148 0.1999
Schistosoma mansoni serine/threonine protein kinase 0.0965 0.2355 0.552
Entamoeba histolytica protein kinase, putative 0.0437 0.0853 0.2588
Trichomonas vaginalis CMGC family protein kinase 0.0449 0.0886 0.2688
Echinococcus granulosus dual specificity 0.0208 0.0201 0.0188
Echinococcus granulosus Glutaredoxin protein 5 0.0607 0.1337 0.1325
Entamoeba histolytica serine/threonine protein kinase, putative 0.0222 0.024 0.0728
Giardia lamblia Kinase, STE STE20 0.0254 0.0332 0.1678
Entamoeba histolytica protein kinase, putative 0.0244 0.0303 0.0919
Echinococcus multilocularis dual specificity 0.0208 0.0201 0.0255
Schistosoma mansoni serine/threonine protein kinase 0.056 0.1203 0.2805
Brugia malayi Immunoglobulin I-set domain containing protein 0.0174 0.0104 0.0112
Loa Loa (eye worm) hypothetical protein 0.0152 0.0043 0.0036
Entamoeba histolytica PH domain containing protein kinase, putative 0.047 0.0947 0.2873
Schistosoma mansoni serine/threonine protein kinase 0.029 0.0435 0.0993
Echinococcus granulosus cAMP dependent protein kinase catalytic subunit 0.0422 0.081 0.0797
Brugia malayi serine/threonine-protein kinase 6 0.0504 0.1044 0.1273
Entamoeba histolytica protein kinase, putative 0.0504 0.1044 0.3167
Echinococcus multilocularis mitogen activated protein kinase 11 0.0617 0.1366 0.1844
Trichomonas vaginalis CMGC family protein kinase 0.0438 0.0855 0.2593
Schistosoma mansoni kinase 0.0727 0.1679 0.3927
Echinococcus multilocularis ribosomal protein s6 kinase beta 1 0.064 0.143 0.1931
Schistosoma mansoni protein kinase 0.0161 0.0067 0.0127
Loa Loa (eye worm) CAMK/TSSK protein kinase 0.0724 0.167 0.2047
Schistosoma mansoni serine/threonine protein kinase 0.0586 0.1278 0.2981
Schistosoma mansoni protein kinase C mu 0.0152 0.0043 0.0069
Echinococcus granulosus tyrosine kinase 0.041 0.0775 0.0762
Echinococcus granulosus tyrosine kinase 0.022 0.0236 0.0223
Trypanosoma cruzi CMGC/DYRK protein kinase, putative 0.0552 0.1181 0.6338
Schistosoma mansoni serine/threonine protein kinase 0.0208 0.0201 0.0442
Onchocerca volvulus 0.022 0.0236 0.0441
Loa Loa (eye worm) hypothetical protein 0.0152 0.0043 0.0036
Echinococcus multilocularis tyrosine protein kinase Srms 0.041 0.0775 0.1038
Loa Loa (eye worm) AGC/PKA protein kinase 0.0422 0.081 0.0984
Loa Loa (eye worm) CAMK/CAMKL/CHK1 protein kinase 0.0792 0.1863 0.2285
Brugia malayi Protein kinase domain containing protein 0.1295 0.3295 0.4056
Echinococcus granulosus protein kinase shaggy 0.0437 0.0853 0.0841
Loa Loa (eye worm) CAMK/MLCK protein kinase 0.0174 0.0104 0.0112
Schistosoma mansoni growth factor receptor-bound protein 0.0188 0.0145 0.031
Entamoeba histolytica protein kinase, putative 0.021 0.0206 0.0626
Loa Loa (eye worm) TK/KIN16 protein kinase 0.1966 0.5208 0.642
Echinococcus multilocularis ephrin type A receptor 4 A 0.0321 0.0522 0.0694
Brugia malayi Ras association domain family 1 isoform A 0.0152 0.0043 0.0036
Echinococcus multilocularis NCK adaptor protein 0.0192 0.0156 0.0194
Loa Loa (eye worm) hypothetical protein 0.0223 0.0244 0.0285
Echinococcus granulosus proto oncogene serine:threonine protein kinase 0.0758 0.1767 0.1756
Echinococcus multilocularis rho associated protein kinase 0.102 0.2512 0.3406
Trichomonas vaginalis CMGC family protein kinase 0.0208 0.0201 0.0609
Entamoeba histolytica protein kinase , putative 0.0504 0.1044 0.3167
Trypanosoma brucei rac serine-threonine kinase, putative 0.1295 0.3295 1
Brugia malayi Protein kinase domain containing protein 0.0663 0.1495 0.1831
Trichomonas vaginalis CAMK family protein kinase 0.0222 0.024 0.0728
Toxoplasma gondii diacylglycerol kinase, putative 0.0152 0.0043 0.0135
Trichomonas vaginalis CAMK family protein kinase 0.0792 0.1864 0.5656
Schistosoma mansoni serine/threonine protein kinase 0.0203 0.0187 0.0409
Leishmania major mitogen activated protein kinase 4, putative;with=GeneDB:LmxM19.1440 0.0302 0.0468 0.2511
Echinococcus multilocularis mitogen activated protein kinase 3 0.0302 0.0468 0.062
Trypanosoma brucei cAMP-dependent protein kinase catalytic subunit 1 0.0422 0.081 0.2457
Loa Loa (eye worm) CAMK/CAMKL/BRSK protein kinase 0.0222 0.024 0.028
Leishmania major protein kinase, putative 0.0345 0.0591 0.3173
Schistosoma mansoni tyrosine kinase 0.0494 0.1017 0.2365
Trichomonas vaginalis CAMK family protein kinase 0.0222 0.024 0.0728
Onchocerca volvulus 0.022 0.0236 0.0441
Entamoeba histolytica hypothetical protein 0.0552 0.1181 0.3585
Trypanosoma brucei cAMP-dependent protein kinase catalytic subunit 2 0.0422 0.081 0.2457
Schistosoma mansoni serine/threonine protein kinase 0.0345 0.0591 0.1362
Schistosoma mansoni protein kinase 0.0258 0.0344 0.0779
Brugia malayi Protein kinase domain containing protein 0.2984 0.8105 1
Echinococcus multilocularis aurora kinase A 0.0504 0.1044 0.1404
Schistosoma mansoni serine/threonine protein kinase 0.0625 0.1389 0.3241
Trichomonas vaginalis CAMK family protein kinase 0.0181 0.0125 0.0378
Echinococcus multilocularis serine:threonine protein kinase 12 B 0.0504 0.1044 0.1404
Loa Loa (eye worm) STE/STE7/MEK1 protein kinase 0.0238 0.0286 0.0337
Entamoeba histolytica protein kinase domain containing protein 0.0206 0.0196 0.0596
Trichomonas vaginalis CAMK family protein kinase 0.0387 0.071 0.2154
Brugia malayi Protein kinase domain containing protein 0.1313 0.3348 0.4122
Echinococcus granulosus serine:threonine protein kinase N2 0.0275 0.0391 0.0378
Loa Loa (eye worm) AGC/PKG protein kinase 0.0203 0.0187 0.0214
Loa Loa (eye worm) hypothetical protein 0.0152 0.0043 0.0036
Giardia lamblia Kinase, CAMK CAMKL 0.023 0.0262 0.1302
Schistosoma mansoni serine/threonine protein kinase 0.0279 0.0404 0.092
Schistosoma mansoni glycogen synthase kinase 3-related (gsk3) (cmgc group III) 0.0437 0.0853 0.1979
Brugia malayi serine/threonine protein kinase 6 0.0504 0.1044 0.1273
Trypanosoma cruzi casein kinase, delta isoform, putative 0.0201 0.018 0.0967
Echinococcus granulosus STE20 serine:threonine protein kinase 0.0606 0.1333 0.1322
Loa Loa (eye worm) hypothetical protein 0.0152 0.004 0.0033
Trichomonas vaginalis STE family protein kinase 0.0238 0.0286 0.0867
Echinococcus multilocularis cyclin dependent kinase 0.0449 0.0886 0.1189
Echinococcus granulosus fibroblast growth factor receptor 4 0.0752 0.1751 0.174
Loa Loa (eye worm) AGC/PKC/ETA protein kinase 0.0868 0.208 0.2555
Schistosoma mansoni vav2 0.0304 0.0474 0.1086
Trichomonas vaginalis CMGC family protein kinase 0.0208 0.0201 0.0609
Echinococcus multilocularis expressed protein 0.0145 0.0023 0.0013
Echinococcus granulosus insulin receptor 0.1313 0.3348 0.3339
Schistosoma mansoni tyrosine kinase 0.0305 0.0478 0.1096
Loa Loa (eye worm) hypothetical protein 0.0294 0.0445 0.0533
Echinococcus granulosus mitogen activated protein kinase 14 0.0617 0.1366 0.1355
Echinococcus granulosus protein tyrosine kinase 0.037 0.0663 0.0651
Loa Loa (eye worm) calcium/calmodulin-dependent protein kinase ID 0.0225 0.0249 0.0291
Leishmania major protein kinase, putative 0.0254 0.0332 0.1779
Brugia malayi casein kinase I 0.029 0.0435 0.0521
Schistosoma mansoni serine/threonine protein kinase 0.0222 0.024 0.0534
Echinococcus multilocularis tyrosine protein kinase transmembrane receptor 0.0187 0.014 0.0172
Trypanosoma cruzi mitogen-activated protein kinase 11, putative 0.0302 0.0468 0.2511
Schistosoma mansoni serine/threonine protein kinase 0.0218 0.0229 0.0508
Echinococcus multilocularis N chimaerin 0.0256 0.0337 0.0441
Loa Loa (eye worm) hypothetical protein 0.072 0.1658 0.2032
Loa Loa (eye worm) PLK/PLK1 protein kinase 0.0792 0.1864 0.2287
Schistosoma mansoni protein kinase C mu 0.0631 0.1407 0.3284
Echinococcus multilocularis serine:threonine protein kinase Chk2 0.021 0.0206 0.0263
Echinococcus multilocularis phosphorylase kinase gamma subunit 0.0236 0.0281 0.0365
Schistosoma mansoni serine/threonine protein kinase 0.021 0.0206 0.0455
Trichomonas vaginalis CAMK family protein kinase 0.0181 0.0125 0.0378
Loa Loa (eye worm) hypothetical protein 0.0463 0.0927 0.1129
Loa Loa (eye worm) CMGC/GSK protein kinase 0.0437 0.0853 0.1038
Plasmodium vivax tyrosine kinase-like protein, putative 0.0143 0.0016 0.0101
Brugia malayi protein kinase C II. 0.0868 0.208 0.2555
Echinococcus granulosus mitogen activated protein kinase 11 0.0617 0.1366 0.1355
Trichomonas vaginalis CAMK family protein kinase 0.0258 0.0342 0.1037
Brugia malayi Protein kinase domain containing protein 0.022 0.0236 0.0276
Trichomonas vaginalis STE family protein kinase 0.0238 0.0286 0.0867
Echinococcus multilocularis serine:threonine protein kinase TAO1 0.0491 0.1005 0.1352
Loa Loa (eye worm) STE/STE20/MSN protein kinase 0.0284 0.0417 0.0499
Brugia malayi Protein kinase domain containing protein 0.0724 0.167 0.2047
Trichomonas vaginalis CAMK family protein kinase 0.0222 0.024 0.0728
Echinococcus multilocularis cAMP dependent protein kinase catalytic subunit 0.0422 0.081 0.1086
Echinococcus granulosus NDR protein kinase 0.064 0.143 0.1418
Schistosoma mansoni serine/threonine protein kinase 0.064 0.143 0.3339
Echinococcus granulosus tyrosine protein kinase Src42A 0.0296 0.0452 0.0439
Loa Loa (eye worm) AGC/RSK/MSK protein kinase 0.0663 0.1495 0.1831
Loa Loa (eye worm) STE/STE20/PAKA protein kinase 0.0158 0.006 0.0057
Echinococcus multilocularis hypothetical protein 0.0172 0.0099 0.0117
Schistosoma mansoni protein kinase 0.0238 0.0286 0.0642
Trypanosoma cruzi mitogen activated protein kinase 4, putative 0.0302 0.0468 0.2511
Echinococcus multilocularis tyrosine protein kinase Fps85D 0.0366 0.0651 0.0869
Echinococcus multilocularis rac serine:threonine kinase 0.0744 0.1728 0.2338
Toxoplasma gondii casein kinase I 0.029 0.0435 0.1376
Plasmodium falciparum RAC-beta serine/threonine protein kinase 0.0696 0.1591 1
Echinococcus granulosus expressed protein 0.0145 0.0023 0.0009
Loa Loa (eye worm) AGC/DMPK/ROCK protein kinase 0.2984 0.8105 1
Brugia malayi MAP kinase sur-1 0.0302 0.0468 0.0562
Echinococcus granulosus tyrosine protein kinase Lyn 0.0584 0.1271 0.1259
Echinococcus granulosus unc 13 munc13 0.0159 0.0061 0.0048
Trichomonas vaginalis AGC family protein kinase 0.0504 0.1044 0.3167
Echinococcus multilocularis PAK box P21 Rho binding 0.0189 0.0147 0.0183
Schistosoma mansoni proto-oncogene tyrosine-protein kinase abl1 0.0188 0.0145 0.031
Echinococcus multilocularis Glutaredoxin protein 5 0.0607 0.1337 0.1804
Echinococcus granulosus serine:threonine protein kinase MARK2 0.043 0.0832 0.082
Brugia malayi SRC-1 0.0494 0.1017 0.124
Trypanosoma cruzi Vacuolar sorting protein 39 domain 1/Vacuolar sorting protein 39 domain 2, putative 0.0223 0.0244 0.1309
Loa Loa (eye worm) AUR protein kinase 0.0504 0.1044 0.1273
Echinococcus granulosus serine:threonine kinase SAD 1 0.0222 0.024 0.0227
Schistosoma mansoni rap gtpase-activating protein 0.0223 0.0244 0.0544
Loa Loa (eye worm) AGC/RSK/RSK protein kinase 0.0992 0.2432 0.2989
Echinococcus multilocularis cyclin dependent kinase 1 0.0449 0.0886 0.1189
Giardia lamblia Aurora kinase 0.0504 0.1044 0.5544
Giardia lamblia Kinase, CMGC MAPK 0.0302 0.0468 0.2418
Schistosoma mansoni serine/threonine protein kinase 0.0262 0.0354 0.0802
Echinococcus granulosus casein kinase i 0.029 0.0435 0.0422
Trichomonas vaginalis CAMK family protein kinase 0.0222 0.024 0.0728
Trichomonas vaginalis AGC family protein kinase 0.016 0.0065 0.0198
Echinococcus multilocularis 0.0284 0.0417 0.055
Echinococcus multilocularis glycogen synthase kinase 3 beta 0.0437 0.0853 0.1145
Brugia malayi Fes/CIP4 homology domain containing protein 0.0242 0.0297 0.035
Onchocerca volvulus 0.0437 0.0853 0.1855
Echinococcus multilocularis proto oncogene serine:threonine protein kinase 0.0758 0.1767 0.2391
Trichomonas vaginalis AGC family protein kinase 0.0648 0.1452 0.4408
Echinococcus granulosus TGF-beta receptor type-1 0.0161 0.0067 0.0054
Trichomonas vaginalis AGC family protein kinase 0.0244 0.0303 0.0919
Brugia malayi serine/threonine-protein kinase PAK 7 0.0723 0.1668 0.2045
Brugia malayi p21/Cdc42/Rac1-activated kinase 0.0158 0.006 0.0057
Brugia malayi Homeodomain interacting protein kinase protein 1 0.0279 0.0404 0.0482
Onchocerca volvulus Tyrosine kinase homolog 0.1685 0.4406 1
Echinococcus granulosus basic fibroblast growth factor receptor 1 A 0.0752 0.1751 0.174
Trichomonas vaginalis CMGC family protein kinase 0.0437 0.0853 0.2588
Echinococcus multilocularis serine:threonine protein kinase PAK 3 0.0258 0.0344 0.0451
Trypanosoma cruzi casein kinase, putative 0.029 0.0435 0.2332
Echinococcus multilocularis cyclin dependent kinase 19 0.0221 0.0237 0.0304
Leishmania major protein kinase A catalytic subunit isoform 1 0.0422 0.081 0.4345
Schistosoma mansoni serine/threonine protein kinase 0.027 0.0376 0.0855
Loa Loa (eye worm) hypothetical protein 0.0166 0.0081 0.0084
Trypanosoma cruzi 5'-AMP-activated protein kinase catalytic subunit alpha, putative 0.0222 0.024 0.1287
Loa Loa (eye worm) TK/FER protein kinase 0.022 0.0236 0.0276
Echinococcus granulosus tyrosine protein kinase Src64B 0.0494 0.1017 0.1005
Trypanosoma cruzi cdc2-related kinase 1 0.0449 0.0886 0.4753
Brugia malayi Kinase associated domain 1 family protein 0.0172 0.0099 0.0106
Echinococcus multilocularis protein kinase c epsilon type 0.0868 0.208 0.2818
Echinococcus granulosus protein kinase c eta type 0.0152 0.0043 0.0029
Echinococcus granulosus activated cdc42 kinase 1 0.0283 0.0415 0.0402
Echinococcus multilocularis dual specificity protein kinase clk2 0.0345 0.0591 0.0788
Schistosoma mansoni serine/threonine protein kinase 0.0792 0.1864 0.4362
Trypanosoma brucei protein kinase A catalytic subunit, putative 0.0422 0.081 0.2457
Loa Loa (eye worm) hypothetical protein 0.0542 0.1152 0.1408
Loa Loa (eye worm) TKL/STKR/TYPE1 protein kinase 0.0189 0.0146 0.0164
Echinococcus multilocularis nervana 2 0.0607 0.1337 0.1804
Entamoeba histolytica protein kinase, putative 0.0189 0.0147 0.0447
Trichomonas vaginalis AGC family protein kinase 0.1295 0.3295 1
Echinococcus multilocularis calcium:calmodulin dependent protein kinase type 0.0225 0.0249 0.0321
Echinococcus multilocularis MAP kinase activated protein kinase 2 0.124 0.3138 0.426
Loa Loa (eye worm) hypothetical protein 0.0256 0.0337 0.04
Trichomonas vaginalis STE family protein kinase 0.0189 0.0147 0.0447
Trypanosoma brucei kinetoplastid kinetochore protein 10 0.0345 0.0591 0.1795
Schistosoma mansoni diacylglycerol kinase theta 0.0152 0.0043 0.0069
Loa Loa (eye worm) CAMK/PHK protein kinase 0.0236 0.0281 0.0331
Echinococcus granulosus protein kinase C gamma type 0.0812 0.1921 0.191
Trichomonas vaginalis AGC family protein kinase 0.016 0.0065 0.0198
Loa Loa (eye worm) STE/STE20/PAKB protein kinase 0.0723 0.1668 0.2045
Echinococcus granulosus cyclin dependent kinase 5 0.0449 0.0886 0.0874
Trypanosoma cruzi casein kinase, putative 0.029 0.0435 0.2332
Echinococcus granulosus dual specificity 0.0208 0.0201 0.0188
Plasmodium vivax calcium-dependent protein kinase 4, putative 0.0225 0.0249 0.1562
Echinococcus granulosus mitogen activated protein kinase 0.0302 0.0468 0.0455
Loa Loa (eye worm) hypothetical protein 0.0201 0.018 0.0206
Echinococcus multilocularis twitchin 0.0159 0.0061 0.0065
Echinococcus granulosus Diacylglycerol kinase theta 0.0152 0.0043 0.0029
Schistosoma mansoni serine/threonine protein kinase 0.1057 0.2619 0.6142
Trypanosoma brucei mitogen activated protein kinase 4, putative 0.0302 0.0468 0.142
Echinococcus multilocularis dual specificity mitogen activated protein 0.0238 0.0286 0.0371
Schistosoma mansoni tyrosine kinase 0.037 0.0663 0.1531
Echinococcus granulosus tyrosine protein kinase ABL1 0.0657 0.148 0.1468
Brugia malayi hypothetical protein 0.0491 0.1005 0.1226
Trichomonas vaginalis CMGC family protein kinase 0.0302 0.0468 0.142
Echinococcus granulosus guanine nucleotide exchange factor VAV2 0.0256 0.0337 0.0324
Brugia malayi Immunoglobulin I-set domain containing protein 0.0163 0.0072 0.0072
Trichomonas vaginalis AGC family protein kinase 0.016 0.0065 0.0198
Trichomonas vaginalis CK1 family protein kinase 0.029 0.0435 0.1319
Loa Loa (eye worm) CK1/CK1/CK1-A protein kinase 0.029 0.0435 0.0521
Schistosoma mansoni serine/threonine protein kinase 0.0345 0.0591 0.1362
Brugia malayi Protein kinase domain containing protein 0.022 0.0236 0.0276
Trichomonas vaginalis AGC family protein kinase 0.0663 0.1495 0.4537
Loa Loa (eye worm) hypothetical protein 0.0249 0.0317 0.0376
Trichomonas vaginalis AGC family protein kinase 0.1295 0.3295 1
Loa Loa (eye worm) CAMK/TSSK protein kinase 0.0724 0.167 0.2047
Brugia malayi bone morphogenetic protein type 1 receptor 0.0189 0.0146 0.0164
Brugia malayi Protein kinase domain containing protein 0.022 0.0236 0.0276
Echinococcus multilocularis tyrosine protein kinase Fgr 0.0494 0.1017 0.1368
Echinococcus granulosus tyrosine kinase|tyrosine protein kinase Fyn 0.041 0.0775 0.0762
Schistosoma mansoni Neurotrimin precursor (hNT) 0.0294 0.0445 0.1017
Schistosoma mansoni serine/threonine kinase 0.0361 0.0638 0.1472
Echinococcus multilocularis ribosomal protein S6 kinase alpha 3 0.0992 0.2432 0.3297
Plasmodium vivax calcium-dependent protein kinase 1, putative 0.0225 0.0249 0.1562
Echinococcus granulosus phosphorylase kinase gamma subunit 0.0236 0.0281 0.0268
Echinococcus granulosus serine:threonine protein kinase 0.0258 0.0342 0.0329
Brugia malayi Protein kinase domain containing protein 0.0153 0.0044 0.0038
Echinococcus multilocularis serine:threonine protein kinase 0.0258 0.0342 0.0448
Plasmodium falciparum protein serine/threonine kinase-1 0.0345 0.0591 0.3717
Echinococcus granulosus serine:threonine protein kinase PLK1 0.0792 0.1864 0.1853
Trichomonas vaginalis AGC family protein kinase 0.0663 0.1495 0.4537
Echinococcus granulosus NCK adaptor protein 0.0188 0.0145 0.0132
Schistosoma mansoni serine/threonine protein kinase 0.0965 0.2355 0.552
Schistosoma mansoni tyrosine kinase 0.0985 0.2415 0.566
Echinococcus granulosus tyrosine protein kinase Fyn 0.0494 0.1017 0.1005
Brugia malayi Temporarily assigned gene name protein 59 0.0223 0.0244 0.0285
Brugia malayi Protein kinase domain containing protein 0.0244 0.0303 0.0358
Loa Loa (eye worm) TK/EGFR protein kinase 0.1632 0.4256 0.5243
Echinococcus multilocularis myotubularin protein 13 0.0201 0.018 0.0227
Trypanosoma cruzi cAMP-dependent protein kinase catalytic subunit 1 0.0422 0.081 0.4345
Schistosoma mansoni nck2/grb4 0.0188 0.0145 0.031
Brugia malayi p70 ribosomal S6 kinase beta 0.1247 0.3158 0.3887
Brugia malayi Phorbol esters/diacylglycerol binding domain 0.0631 0.1407 0.1722
Schistosoma mansoni serine/threonine protein kinase 0.0222 0.024 0.0534
Plasmodium vivax serine/threonine protein kinase, putative 0.0145 0.0023 0.0143
Echinococcus multilocularis serine:threonine protein kinase PLK1 0.0792 0.1864 0.2523
Brugia malayi Protein kinase domain containing protein 0.0783 0.1839 0.2256
Echinococcus multilocularis mitogen activated protein kinase 0.0302 0.0468 0.062
Echinococcus granulosus activin receptor type 0.0573 0.1241 0.1229
Loa Loa (eye worm) CK1/CK1/CK1-D protein kinase 0.029 0.0435 0.0521
Schistosoma mansoni serine/threonine protein kinase 0.0491 0.1005 0.2338
Echinococcus multilocularis fibroblast growth factor receptor 4 0.0752 0.1751 0.2368
Echinococcus granulosus protein kinase c epsilon type 0.0868 0.208 0.207
Echinococcus multilocularis tyrosine protein kinase Src42A 0.0494 0.1017 0.1368
Echinococcus granulosus calcium:calmodulin dependent protein kinase type 0.0225 0.0249 0.0236
Schistosoma mansoni vesicular amine transporter 0.0294 0.0445 0.1017
Leishmania major protein kinase, putative 0.0206 0.0196 0.1053
Loa Loa (eye worm) TK/ABL protein kinase 0.0657 0.148 0.1812
Schistosoma mansoni vam6/vps39 related 0.0223 0.0244 0.0544
Echinococcus granulosus proto oncogene tyrosine protein kinase LCK 0.0494 0.1017 0.1005
Giardia lamblia Kinase, AGC PKA 0.0696 0.1591 0.8519
Toxoplasma gondii protein kinase G AGC kinase family member PKG 0.0203 0.0187 0.0592
Loa Loa (eye worm) TK protein kinase 0.041 0.0775 0.0941
Loa Loa (eye worm) CMGC/CK2 protein kinase 0.0438 0.0855 0.104
Echinococcus multilocularis serine threonine protein kinase 0.0812 0.1921 0.2601
Trichomonas vaginalis CMGC family protein kinase 0.0449 0.0886 0.2688
Entamoeba histolytica casein kinase, putative 0.0438 0.0855 0.2593
Schistosoma mansoni chimerin-related rho-gtpase-activating protein 0.0256 0.0337 0.0763
Entamoeba histolytica protein kinase, putative 0.021 0.0206 0.0626
Brugia malayi cAMP-dependent protein kinase catalytic subunit, putative 0.0422 0.081 0.0984
Trypanosoma cruzi CMGC/DYRK protein kinase, putative 0.0552 0.1181 0.6338
Trichomonas vaginalis CK1 family protein kinase 0.029 0.0435 0.1319
Loa Loa (eye worm) CMGC/SRPK protein kinase 0.0145 0.0023 0.0012
Echinococcus granulosus mitogen activated protein kinase 3 0.0302 0.0468 0.0455
Entamoeba histolytica casein kinase 1, putative 0.029 0.0435 0.1319
Echinococcus granulosus tyrosine protein kinase Fyn 0.0494 0.1017 0.1005
Echinococcus granulosus calcium:calmodulin dependent protein kinase type 0.0709 0.1627 0.1615
Brugia malayi phosphoinositide-dependent protein kinase I 0.0244 0.0303 0.0358
Entamoeba histolytica serine/threonine-protein kinase 3, putative 0.0254 0.0332 0.1006
Loa Loa (eye worm) hypothetical protein 0.0318 0.0515 0.062
Trichomonas vaginalis AGC family protein kinase 0.0418 0.0798 0.2423
Echinococcus multilocularis homeodomain interacting protein kinase 3 0.0279 0.0404 0.0532
Loa Loa (eye worm) hypothetical protein 0.0359 0.0632 0.0764
Giardia lamblia Kinase, CAMK CAMKL 0.023 0.0262 0.1302
Leishmania major protein kinase, putative,SNF1-related protein kinases, putative 0.0222 0.024 0.1287
Echinococcus granulosus serine:threonine protein kinase N2 0.0159 0.0061 0.0047
Onchocerca volvulus 0.102 0.2512 0.5658
Echinococcus granulosus neuroglian 0.0363 0.0643 0.063
Echinococcus multilocularis Diacylglycerol kinase theta 0.0152 0.0043 0.004
Leishmania major protein kinase, putative 0.0504 0.1044 0.5599
Echinococcus multilocularis calcium:calmodulin dependent protein kinase type 0.0709 0.1627 0.2199
Trichomonas vaginalis CAMK family protein kinase 0.0222 0.024 0.0728
Trypanosoma brucei aurora B kinase 0.0504 0.1044 0.3167
Toxoplasma gondii histone kinase SNF1, putative 0.0222 0.024 0.076
Loa Loa (eye worm) CMGC/MAPK/ERK1 protein kinase 0.0302 0.0468 0.0562
Onchocerca volvulus Serine\/threonine kinase homolog 0.0236 0.0281 0.0543
Loa Loa (eye worm) Ras association domain family 1 isoform A 0.0152 0.0043 0.0036
Giardia lamblia Kinase, NEK 0.0418 0.0798 0.4214
Echinococcus granulosus homeodomain interacting protein kinase 3 0.0279 0.0404 0.0391
Trichomonas vaginalis CMGC family protein kinase 0.0437 0.0853 0.2588
Schistosoma mansoni unc-13 (munc13) 0.0159 0.0061 0.0113
Echinococcus granulosus GTPase activating Rap:RanGAP domain 3 0.0223 0.0244 0.0231
Loa Loa (eye worm) thyroid receptor interactor 0.0242 0.0297 0.035
Giardia lamblia Kinase, STE STE20 0.0238 0.0286 0.1428
Trypanosoma cruzi p21-activated kinase 3, putative 0.0158 0.006 0.0319
Trypanosoma cruzi aurora B kinase, putative 0.0504 0.1044 0.5599
Echinococcus multilocularis casein kinase I gamma 0.0291 0.0437 0.0578
Brugia malayi protein unc-22 0.0174 0.0104 0.0112
Echinococcus multilocularis TGF beta receptor type 1 0.0161 0.0067 0.0074
Echinococcus granulosus serine:threonine protein kinase Chk2 0.021 0.0206 0.0193
Brugia malayi Protein kinase domain containing protein 0.0268 0.0372 0.0444
Onchocerca volvulus 0.0204 0.0189 0.0333
Trypanosoma brucei cdc2-related kinase 1 0.0449 0.0886 0.2688
Brugia malayi Serine/threonine-protein kinase Pim-3 0.0758 0.1767 0.2168
Schistosoma mansoni protein kinase 0.0709 0.1627 0.3802
Schistosoma mansoni hypothetical protein 0.0172 0.0099 0.0202
Brugia malayi Hr1 repeat family protein 0.0915 0.2213 0.2718
Onchocerca volvulus 0.0174 0.0104 0.0139
Schistosoma mansoni tyrosine kinase 0.1103 0.2748 0.6446
Brugia malayi probable protein kinase 0.0507 0.1053 0.1284
Echinococcus multilocularis G protein coupled receptor kinase 6 0.0205 0.0192 0.0244
Schistosoma mansoni serine/threonine protein kinase 0.0868 0.208 0.4872
Trichomonas vaginalis CAMK family protein kinase 0.0222 0.024 0.0728
Onchocerca volvulus 0.0542 0.1152 0.2541
Trichomonas vaginalis CMGC family protein kinase 0.0208 0.0201 0.0609
Echinococcus granulosus serine:threonine protein kinase 0.0258 0.0342 0.0329
Brugia malayi serine/threonine kinase 12 0.0504 0.1044 0.1273
Echinococcus granulosus CDC7 cell division cycle 7 0.0153 0.0044 0.0031
Trichomonas vaginalis CAMK family protein kinase 0.0222 0.024 0.0728
Brugia malayi cell division control protein 2 homolog 0.0449 0.0886 0.1078
Echinococcus granulosus protein kinase 0.0284 0.0417 0.0404
Trypanosoma brucei kinetoplastid kinetochore protein 19 0.0345 0.0591 0.1795
Plasmodium falciparum tyrosine kinase-like protein, putative 0.0143 0.0016 0.0101
Loa Loa (eye worm) hypothetical protein 0.0516 0.1079 0.1317
Loa Loa (eye worm) CMGC/GSK protein kinase 0.0437 0.0853 0.1038
Onchocerca volvulus 0.0181 0.0123 0.0182
Brugia malayi Protein kinase domain containing protein 0.0758 0.1767 0.2168
Schistosoma mansoni serine/threonine protein kinase 0.0222 0.024 0.0534
Echinococcus granulosus serine:threonine protein kinase PAK 3 0.0258 0.0344 0.0331
Trichomonas vaginalis CMGC family protein kinase 0.0438 0.0855 0.2593
Plasmodium vivax serine/threonine kinase-1, putative 0.0345 0.0591 0.3717
Trichomonas vaginalis mitogen-activated protein kinase kinase kinase 3, MAPKKK3, MEKK3, putative 0.0158 0.006 0.0181
Trypanosoma cruzi cdc2-related kinase 3 0.0449 0.0886 0.4753
Trichomonas vaginalis AGC family protein kinase 0.0244 0.0303 0.0919
Schistosoma mansoni serine/threonine protein kinase 0.0992 0.2432 0.5702
Echinococcus multilocularis protein tyrosine kinase 0.037 0.0663 0.0886
Schistosoma mansoni serine/threonine protein kinase 0.0302 0.0468 0.1072
Toxoplasma gondii CMGC kinase, MAPK family (ERK) MAPK-1 0.0302 0.0468 0.1482
Trypanosoma cruzi casein kinase, delta isoform, putative 0.029 0.0435 0.2332
Toxoplasma gondii cell-cycle-associated protein kinase CLK, putative 0.0345 0.0591 0.1873
Loa Loa (eye worm) CMGC/MAPK/JNK protein kinase 0.1057 0.2619 0.3221
Onchocerca volvulus Serine\/threonine kinase homolog 0.0792 0.1864 0.4172
Loa Loa (eye worm) hypothetical protein 0.0223 0.0244 0.0285
Loa Loa (eye worm) STE/STE20/TAO protein kinase 0.0491 0.1005 0.1226
Echinococcus multilocularis c src tyrosine kinase 0.0305 0.0478 0.0634
Brugia malayi Pleckstrin Homology Domain 0.0201 0.018 0.0206
Echinococcus granulosus epidermal growth factor receptor 0.1103 0.2748 0.2738
Brugia malayi Stress-activated protein kinase jnk-1 0.1057 0.2619 0.3221
Entamoeba histolytica protein kinase, putative 0.0258 0.0344 0.1044
Schistosoma mansoni adapter molecule crk 0.0188 0.0145 0.031
Onchocerca volvulus Serine\/threonine protein kinase homolog 0.0758 0.1767 0.395
Entamoeba histolytica diacylglycerol kinase, putative 0.0152 0.0043 0.0129
Trichomonas vaginalis CAMK family protein kinase 0.0222 0.024 0.0728
Echinococcus granulosus growth factor receptor bound protein 2 0.0192 0.0156 0.0143
Trichomonas vaginalis AGC family protein kinase 0.016 0.0065 0.0198
Schistosoma mansoni hypothetical protein 0.0172 0.0099 0.0202
Trypanosoma brucei cdc2-related kinase 3 0.0449 0.0886 0.2688
Loa Loa (eye worm) STE/STE20/MST protein kinase 0.0802 0.1893 0.2323
Giardia lamblia Kinase, CK1 Casein kinase 0.029 0.0435 0.2237
Trypanosoma cruzi kinetoplastid kinetochore protein 19, putative 0.0345 0.0591 0.3173
Echinococcus multilocularis serine:threonine protein kinase receptor R3 0.0161 0.0067 0.0074
Giardia lamblia Kinase, NEK 0.0418 0.0798 0.4214
Trypanosoma brucei protein kinase, putative 0.0437 0.0853 0.2588
Trichomonas vaginalis CAMK family protein kinase 0.0387 0.071 0.2154
Schistosoma mansoni serine/threonine protein kinase 0.0203 0.0187 0.0409
Echinococcus multilocularis tyrosine protein kinase Src64B 0.0494 0.1017 0.1368
Trypanosoma cruzi STE/STE11 serine/threonine-protein kinase, putative 0.0206 0.0196 0.1053
Echinococcus granulosus tyrosine protein kinase Fyn 0.0494 0.1017 0.1005
Trichomonas vaginalis CMGC family protein kinase 0.0208 0.0201 0.0609
Loa Loa (eye worm) CAMK/CAMKL/MELK protein kinase 0.0354 0.0615 0.0744
Brugia malayi Casein kinase II, alpha chain 0.0438 0.0855 0.104
Leishmania major cell division protein kinase 2,cdc2-related kinase 0.0449 0.0886 0.4753
Giardia lamblia Kinase, CMGC CDK 0.0449 0.0886 0.4688
Leishmania major mitogen-activated protein kinase 3, putative,map kinase 3, putative 0.0617 0.1366 0.7331
Trypanosoma cruzi STE/STE20 serine/threonine-protein kinase, putative 0.0254 0.0332 0.1779
Entamoeba histolytica protein kinase, putative 0.0225 0.0249 0.0754
Brugia malayi Protein kinase domain containing protein 0.0221 0.0237 0.0276
Brugia malayi SH2 domain containing protein 0.0366 0.0651 0.0788
Loa Loa (eye worm) hypothetical protein 0.1359 0.3479 0.4283
Schistosoma mansoni serine/threonine protein kinase 0.0552 0.1181 0.2753
Trichomonas vaginalis AGC family protein kinase 0.0422 0.081 0.2457
Trichomonas vaginalis CMGC family protein kinase 0.0153 0.0044 0.0133
Brugia malayi Dual-specificity tyrosine-phosphorylation regulated kinase 2 0.0208 0.0201 0.0232
Trichomonas vaginalis CK1 family protein kinase 0.029 0.0435 0.1319
Echinococcus granulosus cGMP dependent protein kinase 1 0.0203 0.0187 0.0174
Leishmania major mitogen activated protein kinase, putative,map kinase, putative 0.0302 0.0468 0.2511
Giardia lamblia Kinase, STE STE20 0.0258 0.0344 0.1745
Brugia malayi Cam kinase protein 1 0.0225 0.0249 0.0291
Trypanosoma cruzi mitogen-activated protein kinase 3, putative 0.0617 0.1366 0.7331
Trichomonas vaginalis AGC family protein kinase 0.016 0.0065 0.0198
Plasmodium falciparum serine/threonine protein kinase, putative 0.0504 0.1044 0.6558
Trichomonas vaginalis CMGC family protein kinase 0.0438 0.0855 0.2593
Plasmodium vivax serine/threonine protein kinase KIN, putative 0.023 0.0262 0.1649
Loa Loa (eye worm) G protein-coupled receptor kinase 1 0.0205 0.0192 0.0221
Loa Loa (eye worm) TKL/STKR/TYPE2 protein kinase 0.0151 0.0037 0.003
Trypanosoma cruzi cAMP-dependent protein kinase catalytic subunit 3 0.0422 0.081 0.4345
Echinococcus multilocularis serine:threonine protein kinase MRCK beta 0.0619 0.1372 0.1852
Echinococcus multilocularis tyrosine protein kinase lyn tyrosine protein kinase blk 0.0494 0.1017 0.1368
Loa Loa (eye worm) hypothetical protein 0.039 0.0718 0.0871
Echinococcus granulosus casein kinase I alpha 0.029 0.0435 0.0422
Echinococcus multilocularis casein kinase ii subunit alpha 0.0438 0.0855 0.1147
Echinococcus granulosus 3'partial|tyrosine protein kinase Fgr 0.0494 0.1017 0.1005
Trypanosoma brucei protein kinase, putative 0.031 0.049 0.1488
Trypanosoma brucei serine/arginine-rich protein specific kinase SRPK, putative 0.0145 0.0023 0.0069
Loa Loa (eye worm) hypothetical protein 0.0422 0.081 0.0984
Echinococcus multilocularis serine:threonine protein kinase N2 0.0709 0.1628 0.2201
Trichomonas vaginalis AGC family protein kinase 0.016 0.0065 0.0198
Entamoeba histolytica protein kinase, putative 0.0552 0.1181 0.3585
Schistosoma mansoni atypical protein kinase C 0.1075 0.2671 0.6264
Loa Loa (eye worm) TK protein kinase 0.0263 0.0356 0.0424
Onchocerca volvulus 0.1015 0.2499 0.5629
Trypanosoma brucei dual specificity tyrosine-phosphorylation-regulated kinase 2, putative 0.0208 0.0201 0.0609
Loa Loa (eye worm) TK/FER protein kinase 0.022 0.0236 0.0276
Echinococcus multilocularis tyrosine protein kinase Blk 0.041 0.0775 0.1038
Giardia lamblia Kinase, CMGC GSK 0.0437 0.0853 0.451
Trichomonas vaginalis STE family protein kinase 0.0258 0.0344 0.1044
Brugia malayi Tyrosine-protein kinase abl-1 0.0472 0.0954 0.1162
Plasmodium falciparum NIMA related kinase 1 0.0418 0.0798 0.5018
Loa Loa (eye worm) variant SH3 domain-containing protein 0.0152 0.0043 0.0036
Toxoplasma gondii aurora kinase 0.0504 0.1044 0.3304
Loa Loa (eye worm) CAMK/CAMK2 protein kinase 0.0225 0.0249 0.0291
Trichomonas vaginalis CAMK family protein kinase 0.0792 0.1864 0.5656
Loa Loa (eye worm) TK/FER protein kinase 0.0366 0.0651 0.0788
Schistosoma mansoni tyrosine kinase 0.0985 0.2415 0.566
Trypanosoma cruzi polo-like protein kinase, putative 0.0792 0.1864 1
Brugia malayi Protein kinase domain containing protein 0.0291 0.0437 0.0524
Echinococcus granulosus serine:threonine protein kinase 12 B 0.0504 0.1044 0.1032
Entamoeba histolytica serine/threonine- protein kinase 6, putative 0.0504 0.1044 0.3167
Schistosoma mansoni tyrosine kinase 0.1313 0.3348 0.7861
Entamoeba histolytica PH domain containing protein kinase, putative 0.0744 0.1728 0.5245
Echinococcus granulosus tyrosine protein kinase Blk 0.041 0.0775 0.0762
Plasmodium vivax glycogen synthase kinase 3, putative 0.0437 0.0853 0.5361
Echinococcus multilocularis basic fibroblast growth factor receptor 1 A 0.0752 0.1751 0.2368
Trichomonas vaginalis CAMK family protein kinase 0.0792 0.1864 0.5656
Schistosoma mansoni rac gtpase activating protein 0.0152 0.0043 0.0069
Brugia malayi Tyrosine-protein kinase abl-1 0.027 0.0376 0.0449
Echinococcus multilocularis tyrosine protein kinase lyn lyn a protein tyrosine kinase lymphocyte specific protein tyrosine kinase 0.0494 0.1017 0.1368
Trichomonas vaginalis CAMK family protein kinase 0.0354 0.0615 0.1867
Echinococcus multilocularis growth factor receptor bound protein 2 0.0188 0.0145 0.0179
Entamoeba histolytica protein kinase, putative 0.0237 0.0284 0.0863
Loa Loa (eye worm) camk/mapkapk/mapkapk protein kinase 0.124 0.3138 0.3862
Echinococcus granulosus Protein kinase C brain isozyme 0.0965 0.2355 0.2345
Onchocerca volvulus 0.022 0.0236 0.0441
Echinococcus multilocularis insulin receptor 0.1313 0.3348 0.4546
Loa Loa (eye worm) CAMK/PKD protein kinase 0.0631 0.1407 0.1722
Brugia malayi Variant SH3 domain containing protein 0.0188 0.0145 0.0163
Trypanosoma cruzi STE/STE20 serine/threonine-protein kinase, putative 0.0158 0.006 0.0319
Echinococcus granulosus tyrosine protein kinase Srms 0.0677 0.1536 0.1524
Giardia lamblia Kinase, CMGC DYRK 0.0208 0.0201 0.0967
Loa Loa (eye worm) AGC/PKA protein kinase 0.0422 0.081 0.0984
Onchocerca volvulus 0.059 0.1289 0.2855
Echinococcus multilocularis insulin growth factor 1 receptor beta 0.1329 0.3392 0.4606
Onchocerca volvulus 0.022 0.0236 0.0441
Trichomonas vaginalis STE family protein kinase 0.0258 0.0344 0.1044
Onchocerca volvulus 0.022 0.0236 0.0441
Echinococcus granulosus nervana 2 0.0607 0.1337 0.1325
Brugia malayi diacylglycerol kinase 0.0152 0.0043 0.0036
Loa Loa (eye worm) CAMK/PIM protein kinase 0.0758 0.1767 0.2168
Echinococcus granulosus tyrosine protein kinase HCK 0.0306 0.048 0.0468
Echinococcus multilocularis mitogen activated protein kinase 14 0.0617 0.1366 0.1844
Toxoplasma gondii calcium-dependent protein kinase CDPK2A 0.0225 0.0249 0.0787
Brugia malayi map kinase activated protein kinase protein 2 0.124 0.3138 0.3862
Plasmodium falciparum casein kinase 2, alpha subunit 0.0438 0.0855 0.537
Brugia malayi STE20-like kinase MST 0.0802 0.1893 0.2323
Loa Loa (eye worm) hypothetical protein 0.0283 0.0415 0.0496
Schistosoma mansoni tyrosine kinase 0.0985 0.2415 0.566
Schistosoma mansoni nephrin 0.0379 0.0686 0.1586
Trichomonas vaginalis STE family protein kinase 0.0418 0.0798 0.2423
Brugia malayi Protein kinase domain containing protein 0.0554 0.1187 0.1451
Plasmodium falciparum cGMP-dependent protein kinase 0.0203 0.0187 0.1174
Onchocerca volvulus 0.022 0.0236 0.0441
Echinococcus multilocularis serine:threonine kinase SAD 1 0.0222 0.024 0.0309
Schistosoma mansoni protein kinase 0.0709 0.1627 0.3802
Trypanosoma brucei STE/STE11 serine/threonine-protein kinase, putative 0.0206 0.0196 0.0596
Schistosoma mansoni serine/threonine protein kinase 0.0174 0.0104 0.0215
Echinococcus granulosus sodium:potassium dependent atpase beta subunit 0.0607 0.1337 0.1325
Entamoeba histolytica protein kinase, putative 0.0231 0.0267 0.0811
Brugia malayi hypothetical protein 0.022 0.0236 0.0276
Echinococcus granulosus Vam6:Vps39 protein 0.0223 0.0244 0.0231
Trypanosoma cruzi casein kinase II, putative 0.0438 0.0855 0.4585
Echinococcus granulosus calcium:calmodulin dependent protein kinase type 0.0225 0.0249 0.0236
Entamoeba histolytica protein kinase domain containing protein 0.0504 0.1044 0.3167
Brugia malayi Protein kinase domain containing protein 0.022 0.0236 0.0276
Trypanosoma cruzi kinetoplastid kinetochore protein 10, putative 0.0345 0.0591 0.3173
Entamoeba histolytica protein kinase, putative 0.0145 0.0023 0.0069
Trichomonas vaginalis AGC family protein kinase 0.1295 0.3295 1
Loa Loa (eye worm) hypothetical protein 0.046 0.0918 0.1119
Trypanosoma cruzi kinetoplastid kinetochore protein 19, putative 0.0345 0.0591 0.3173
Brugia malayi Protein kinase domain containing protein 0.0283 0.0415 0.0496
Giardia lamblia Kinase, PLK 0.0792 0.1864 1
Echinococcus multilocularis nervana 2 0.0607 0.1337 0.1804
Schistosoma mansoni serine/threonine protein kinase 0.0792 0.1863 0.4359
Trypanosoma cruzi cAMP-dependent protein kinase catalytic subunit 3 0.0422 0.081 0.4345
Schistosoma mansoni serine/threonine protein kinase 0.0262 0.0354 0.0802
Echinococcus multilocularis epidermal growth factor receptor 0.1632 0.4256 0.5783
Loa Loa (eye worm) CMGC/CDK/CDC2 protein kinase 0.0449 0.0886 0.1078
Trichomonas vaginalis STE family protein kinase 0.0238 0.0286 0.0867
Loa Loa (eye worm) raf kinase 0.0152 0.0043 0.0036
Echinococcus multilocularis transfer RNA-Thr 0.0283 0.0415 0.0548
Loa Loa (eye worm) TK/FER protein kinase 0.022 0.0236 0.0276
Echinococcus granulosus calcium:calmodulin dependent protein kinase I 0.021 0.0206 0.0193
Echinococcus granulosus twitchin 0.0453 0.0897 0.0885
Schistosoma mansoni protein kinase C 0.0159 0.0061 0.0113
Echinococcus multilocularis mitogen activated protein kinase 14 0.0617 0.1366 0.1844
Echinococcus multilocularis 3 phosphoinositide dependent protein kinase 1 0.0244 0.0303 0.0395
Entamoeba histolytica protein kinase, putative 0.0208 0.0201 0.0609
Entamoeba histolytica protein kinase, putative 0.064 0.143 0.4339
Echinococcus granulosus cAMP dependent protein kinase catalytic subunit 0.0422 0.081 0.0797
Loa Loa (eye worm) CMGC/CDK/CDK8 protein kinase 0.0221 0.0237 0.0276
Onchocerca volvulus 0.039 0.0718 0.1545
Echinococcus multilocularis raf serine:threonine protein kinase 0.027 0.0376 0.0494
Onchocerca volvulus 0.0223 0.0244 0.0459
Loa Loa (eye worm) TK protein kinase 0.0822 0.1949 0.2392
Plasmodium vivax unspecified product 0.0438 0.0855 0.537
Toxoplasma gondii AGC kinase 0.0422 0.081 0.2564
Toxoplasma gondii CMGC kinase, CK2 family 0.0438 0.0855 0.2706
Schistosoma mansoni serine/threonine protein kinase 0.043 0.0832 0.1931
Trypanosoma cruzi polo-like protein kinase, putative 0.0792 0.1864 1
Echinococcus granulosus dual specificity mitogen activated protein 0.0238 0.0286 0.0273
Trichomonas vaginalis AGC family protein kinase 0.1295 0.3295 1
Echinococcus multilocularis tyrosine protein kinase Btk29A 0.0885 0.2128 0.2883
Echinococcus multilocularis unc 13 (munc13) 0.0159 0.0061 0.0065
Echinococcus multilocularis protein KINase family member (kin 25) 0.0181 0.0124 0.0151
Echinococcus granulosus rho-associated protein kinase 1 0.102 0.2512 0.2502
Schistosoma mansoni serine/threonine protein kinase 0.0302 0.0468 0.1071
Trypanosoma brucei STE20-like serine/threonine-protein kinase 1, putative 0.0254 0.0332 0.1006
Schistosoma mansoni tyrosine kinase 0.0494 0.1017 0.2365
Loa Loa (eye worm) AGC/DMPK/GEK protein kinase 0.1205 0.3039 0.3739
Echinococcus granulosus melanoma receptor tyrosine protein kinase 0.1103 0.2748 0.2738
Plasmodium vivax calcium-dependent protein kinase 3, putative 0.0225 0.0249 0.1562
Loa Loa (eye worm) CK1/CK1/CK1-A protein kinase 0.029 0.0435 0.0521
Trypanosoma brucei 5'-AMP-activated protein kinase catalytic subunit alpha, putative 0.0222 0.024 0.0728
Schistosoma mansoni protein kinase 0.0284 0.0417 0.0952
Loa Loa (eye worm) hypothetical protein 0.0152 0.0043 0.0036
Trichomonas vaginalis CAMK family protein kinase 0.0222 0.024 0.0728
Entamoeba histolytica PH domain containing protein kinase, putative 0.0207 0.0198 0.06
Onchocerca volvulus 0.0159 0.0061 0.004
Toxoplasma gondii calcium-dependent protein kinase CDPK3 0.0225 0.0249 0.0787
Trypanosoma cruzi mitogen activated protein kinase 2, putative 0.0302 0.0468 0.2511
Loa Loa (eye worm) hypothetical protein 0.0719 0.1656 0.203
Echinococcus multilocularis calcium:calmodulin dependent protein kinase type 0.0225 0.0249 0.0321
Trypanosoma cruzi casein kinase, putative 0.029 0.0435 0.2332
Brugia malayi protein-tyrosine kinase 0.041 0.0775 0.0941
Echinococcus multilocularis Immunoglobulin 0.0294 0.0445 0.0588
Schistosoma mansoni tyrosine kinase 0.022 0.0236 0.0525
Trypanosoma brucei protein kinase, putative 0.0206 0.0196 0.0596
Brugia malayi Protein kinase c protein 2 0.0414 0.0788 0.0958
Echinococcus multilocularis basement membrane specific heparan sulfate 0.0294 0.0445 0.0588
Loa Loa (eye worm) hypothetical protein 0.0166 0.0082 0.0084
Loa Loa (eye worm) CMGC/DYRK/DYRK2 protein kinase 0.0208 0.0201 0.0232
Onchocerca volvulus 0.029 0.0435 0.0895
Brugia malayi Temporarily assigned gene name protein 59 0.0411 0.0778 0.0945
Brugia malayi Dual specificity mitogen-activated protein kinase kinase mek-2 0.0238 0.0286 0.0337
Brugia malayi Calcium/calmodulin-dependent protein kinase type II alpha chain 0.0484 0.0986 0.1203
Echinococcus multilocularis serine:threonine protein kinase PAK 4 0.0624 0.1384 0.1868
Brugia malayi Fibronectin type III domain containing protein 0.0309 0.0489 0.0587
Loa Loa (eye worm) AUR protein kinase 0.0504 0.1044 0.1273
Trypanosoma brucei casein kinase I, isoform 2 0.029 0.0435 0.1319
Plasmodium vivax cAMP-dependent protein kinase catalytic subunit, putative 0.0422 0.081 0.5089
Trypanosoma cruzi casein kinase, putative 0.029 0.0435 0.2332
Brugia malayi Furin-like cysteine rich region family protein 0.1632 0.4256 0.5243
Loa Loa (eye worm) hypothetical protein 0.0152 0.0043 0.0036
Loa Loa (eye worm) hypothetical protein 0.0258 0.0342 0.0406
Brugia malayi ephrin receptor 1 precursor 0.0213 0.0215 0.025
Loa Loa (eye worm) STE/STE20/KHS protein kinase 0.0783 0.1839 0.2256
Toxoplasma gondii protein kinase, cAMP-dependent, catalytic chain 0.0422 0.081 0.2564
Brugia malayi intracellular kinase 0.0437 0.0853 0.1038
Trypanosoma cruzi casein kinase, putative 0.029 0.0435 0.2332
Giardia lamblia Kinase, CMGC GSK 0.0437 0.0853 0.451
Loa Loa (eye worm) variant SH3 domain-containing protein 0.0188 0.0145 0.0163
Schistosoma mansoni protein kinase 0.0206 0.0196 0.0431
Plasmodium vivax casein kinase 1, putative 0.029 0.0435 0.2731
Loa Loa (eye worm) STE/STE20/SLK protein kinase 0.0268 0.0372 0.0444
Trichomonas vaginalis CAMK family protein kinase 0.0222 0.024 0.0728
Loa Loa (eye worm) hypothetical protein 0.0284 0.0417 0.0499
Plasmodium falciparum calcium-dependent protein kinase 5 0.0225 0.0249 0.1562
Echinococcus granulosus Rac GTPase activating protein 1 0.0152 0.0043 0.0029
Entamoeba histolytica cell division protein kinase 2, putative 0.0449 0.0886 0.2688
Echinococcus multilocularis dual specificity 0.0208 0.0201 0.0255
Brugia malayi Protein kinase domain containing protein 0.0552 0.1181 0.1443
Schistosoma mansoni mitogen-activated protein kinase kinase kinase 3 mapkkk3 mekk3 0.0223 0.0244 0.0544
Schistosoma mansoni serine/threonine-protein kinase 0.0744 0.1728 0.4042
Brugia malayi Protein kinase domain containing protein 0.0354 0.0615 0.0744
Echinococcus multilocularis serine:threonine protein kinase MARK2 0.043 0.0832 0.1117
Loa Loa (eye worm) hypothetical protein 0.0181 0.0124 0.0137
Trypanosoma cruzi rac serine-threonine kinase, putative 0.0696 0.1591 0.8537
Echinococcus multilocularis maternal embryonic leucine zipper kinase 0.0181 0.0125 0.0152
Loa Loa (eye worm) CMGC/CLK protein kinase 0.0345 0.0591 0.0714
Entamoeba histolytica protein kinase, putative 0.0145 0.0023 0.0069
Echinococcus multilocularis C2 calcium dependent membrane targeting 0.0159 0.0061 0.0065
Echinococcus multilocularis telomerase reverse transcriptase subunit 0.0166 0.0081 0.0092
Giardia lamblia Kinase, CDC7 0.0153 0.0044 0.0115
Echinococcus multilocularis serine threonine protein kinase nrc serine threonine protein kinase gad 0.0696 0.1591 0.2151
Echinococcus granulosus RNA directed DNA polymerase 0.0166 0.0081 0.0068
Loa Loa (eye worm) hypothetical protein 0.0309 0.0489 0.0587
Trichomonas vaginalis CAMK family protein kinase 0.0222 0.024 0.0728
Schistosoma mansoni serine/threonine protein kinase 0.0619 0.1372 0.3202
Echinococcus granulosus tyrosine protein kinase transmembrane receptor 0.0187 0.014 0.0127
Echinococcus multilocularis tyrosine protein kinase Abl 0.0472 0.0954 0.1282
Echinococcus multilocularis STE20 serine:threonine protein kinase 0.0606 0.1333 0.1799
Echinococcus multilocularis casein kinase I delta 0.029 0.0435 0.0574
Trichomonas vaginalis CAMK family protein kinase 0.0792 0.1864 0.5656
Loa Loa (eye worm) CMGC/CDK/CDC2 protein kinase 0.0449 0.0886 0.1078
Echinococcus multilocularis serine:threonine protein kinase N2 0.0275 0.0391 0.0515
Trichomonas vaginalis CAMK family protein kinase 0.0222 0.024 0.0728
Echinococcus multilocularis Immunoglobulin 0.0294 0.0445 0.0588
Echinococcus granulosus cyclin dependent kinase 0.0449 0.0886 0.0874
Schistosoma mansoni serine/threonine protein kinase 0.043 0.0832 0.1931
Echinococcus multilocularis enhancer of mRNA decapping protein 4 0.0333 0.0555 0.0739
Loa Loa (eye worm) sex muscle abnormal protein 5 0.0188 0.0145 0.0163
Loa Loa (eye worm) AGC/RSK/P70 protein kinase 0.1247 0.3158 0.3887
Schistosoma mansoni protein kinase 0.0258 0.0344 0.0779
Plasmodium falciparum calcium-dependent protein kinase 3 0.0225 0.0249 0.1562
Loa Loa (eye worm) hypothetical protein 0.072 0.1658 0.2032
Loa Loa (eye worm) hypothetical protein 0.0204 0.0189 0.0217
Loa Loa (eye worm) TK/FER protein kinase 0.022 0.0236 0.0276
Echinococcus granulosus enhancer of mRNA decapping protein 4 0.0333 0.0555 0.0543
Echinococcus granulosus Immunoglobulin 0.0294 0.0445 0.0432
Trichomonas vaginalis AGC family protein kinase 0.016 0.0065 0.0198
Echinococcus granulosus dual specificity 0.0552 0.1181 0.1169
Trichomonas vaginalis CAMK family protein kinase 0.0222 0.024 0.0728

Activities

Activity type Activity value Assay description Source Reference
Potency (functional) 1.1689 uM PUBCHEM_BIOASSAY: Primary qHTS for delayed death inhibitors of the malarial parasite plastid, 96 hour incubation. (Class of assay: confirmatory) [Related pubchem assays (depositor defined):AID488745, AID488752, AID488774, AID504848, AID504850] ChEMBL. No reference
Potency (functional) 5.6234 uM PUBCHEM_BIOASSAY: qHTS for Inhibitors of TGF-b: Cytotox Counterscreen. (Class of assay: confirmatory) [Related pubchem assays (depositor defined):AID588855, AID588860] ChEMBL. No reference
Potency (functional) 5.8584 uM PUBCHEM_BIOASSAY: Primary qHTS for delayed death inhibitors of the malarial parasite plastid, 48 hour incubation. (Class of assay: confirmatory) [Related pubchem assays (depositor defined):AID488752, AID488774, AID504848, AID504850] ChEMBL. No reference
Potency (functional) 22.3872 uM PUBCHEM_BIOASSAY: qHTS for Inhibitors of binding or entry into cells for Lassa Virus. (Class of assay: confirmatory) [Related pubchem assays (depositor defined):AID463114, AID540249] ChEMBL. No reference
Potency (functional) = 28.1838 um PUBCHEM_BIOASSAY: qHTS Assay for Inhibitors of Human Jumonji Domain Containing 2E (JMJD2E). (Class of assay: confirmatory) ChEMBL. No reference
Potency (functional) = 28.1838 um PUBCHEM_BIOASSAY: qHTS Assay for Inhibitors of Aldehyde Dehydrogenase 1 (ALDH1A1). (Class of assay: confirmatory) [Related pubchem assays: 1030 (qHTS Validation Assay for Inhibitors of aldehyde dehydrogenase 1 (ALDH1A1))] ChEMBL. No reference
Potency (functional) 29.081 uM PUBCHEM_BIOASSAY: qHTS screen for small molecules that inhibit ELG1-dependent DNA repair in human embryonic kidney (HEK293T) cells expressing luciferase-tagged ELG1. (Class of assay: confirmatory) [Related pubchem assays (depositor defined):AID493107, AID493125] ChEMBL. No reference
Potency (functional) 29.0929 uM PUBCHEM_BIOASSAY: Nrf2 qHTS screen for inhibitors. (Class of assay: confirmatory) [Related pubchem assays (depositor defined):AID493153, AID493163, AID504648] ChEMBL. No reference
Potency (functional) 31.6228 uM PUBCHEM_BIOASSAY: qHTS assay for re-activators of p53 using a Luc reporter. (Class of assay: confirmatory) [Related pubchem assays (depositor defined):AID504709] ChEMBL. No reference
Potency (functional) 100 uM PUBCHEM_BIOASSAY: qHTS for Inhibitors of Polymerase Iota. (Class of assay: confirmatory) [Related pubchem assays (depositor defined):AID588623] ChEMBL. No reference

Phenotypes

Whole-cell/tissue/organism interactions

Species name Source Reference Is orphan
Plasmodium falciparum ChEMBL23
Homo sapiens ChEMBL23

Many chemical entities in TDR Targets come from high-throughput screenings with whole cells or tissue samples, and not all assayed compounds have been tested against a single a single target protein, probably because they get ruled out during screening process. Even if these compounds may have not been of interest in the original screening, they may come as interesting leads for other screening assays. Furthermore, we may be able to propose drug-target associations using chemical similarities and network patterns.

Annotated phenotypes:

We have no manually annotated phenotypes for this drug. What does this mean? / Care to help?
In TDR Targets, information about phenotypes that are caused by drugs, or by genetic manipulation of cells (e.g. gene knockouts or knockdowns) is manually curated from the literature. These descriptions help to describe the potential of the target for drug development. If no information is available for this gene or if the information is incomplete, this may mean that i) the papers containing this information either appeared after the curation effort for this organism was carried out or they were inadvertently missed by curators; or that ii) the curation effort for this organism has not yet started.
 
In any case, if you have information about papers containing relevant validation data for this target, please log in using your TDR Targets username and password and send them to us using the corresponding form in this page (only visible to registered users) or contact us.

External resources for this compound

Bibliographic References

No literature references available for this target.

If you have references for this compound, please enter them in a user comment (below) or Contact us.