Detailed information for compound 135371

Basic information

Technical information
  • Name: Unnamed compound
  • MW: 539.582 | Formula: C30H29N5O5
  • H donors: 6 H acceptors: 4 LogP: 3.87 Rotable bonds: 14
    Rule of 5 violations (Lipinski): 3
  • SMILES: ONC(=O)[C@H](Cc1c[nH]c2c1cccc2)NC(=O)C(Cc1c[nH]c2c1cccc2)NC(=O)OCc1ccccc1
  • InChi: 1S/C30H29N5O5/c36-28(33-27(29(37)35-39)15-21-17-32-25-13-7-5-11-23(21)25)26(14-20-16-31-24-12-6-4-10-22(20)24)34-30(38)40-18-19-8-2-1-3-9-19/h1-13,16-17,26-27,31-32,39H,14-15,18H2,(H,33,36)(H,34,38)(H,35,37)/t26?,27-/m0/s1
  • InChiKey: NXIOVRTXRHTPDW-GEVKEYJPSA-N  


Substructure search Similarity search

Network

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Synonyms

No synonyms found for this compound

Targets

Known targets for this compound

Species Target name Source Bibliographic reference
Homo sapiens tolloid-like 2 Starlite/ChEMBL References

Predicted pathogen targets for this compound

By orthology
Species Potential target Known druggable target/s Ortholog Group
Echinococcus granulosus Tolloid protein 1 Get druggable targets OG5_130155 All targets in OG5_130155
Schistosoma japonicum Iroquois-class homeodomain protein IRX-1, putative Get druggable targets OG5_130155 All targets in OG5_130155
Schistosoma japonicum Tolloid-like protein 2 precursor, putative Get druggable targets OG5_130155 All targets in OG5_130155
Schistosoma japonicum Bone morphogenetic protein 1 homolog precursor, putative Get druggable targets OG5_130155 All targets in OG5_130155
Schistosoma japonicum ko:K09608 tolloid-like protein 1, putative Get druggable targets OG5_130155 All targets in OG5_130155
Schistosoma japonicum IPR000859,CUB,domain-containing Get druggable targets OG5_130155 All targets in OG5_130155
Echinococcus multilocularis Tolloid protein 1 Get druggable targets OG5_130155 All targets in OG5_130155
Schistosoma mansoni subfamily M12A unassigned peptidase (M12 family) Get druggable targets OG5_130155 All targets in OG5_130155
Loa Loa (eye worm) hypothetical protein Get druggable targets OG5_130155 All targets in OG5_130155
Loa Loa (eye worm) AStacin protease Get druggable targets OG5_130155 All targets in OG5_130155
Loa Loa (eye worm) bone morphogenetic protein 1b Get druggable targets OG5_130155 All targets in OG5_130155
By sequence similarity to non orthologous known druggable targets
No druggable targets predicted by sequence similarity
Obtained from network model

Ranking Plot

Putative Targets List

Species Potential target Raw Global Species
Plasmodium vivax geranylgeranyltransferase, putative 0.0026 0.0048 0.0195
Loa Loa (eye worm) hypothetical protein 0.0495 0.1794 0.6606
Onchocerca volvulus Heterochromatin protein 1 homolog 0.0046 0.0119 0.1793
Mycobacterium ulcerans 4'-phosphopantetheinyl transferase 0.0024 0.0039 0.0293
Loa Loa (eye worm) hypothetical protein 0.0102 0.0329 0.1212
Loa Loa (eye worm) hypothetical protein 0.0043 0.0109 0.0401
Onchocerca volvulus 0.0017 0.0013 0.0071
Schistosoma mansoni sodium-dependent neurotransmitter transporter 0.0043 0.0109 0.0179
Echinococcus multilocularis geranylgeranyl transferase type I beta subunit 0.0026 0.0048 0.0034
Giardia lamblia Sgs1 DNA helicase, putative 0.0024 0.0037 0.0156
Plasmodium falciparum importin beta, putative 0.0031 0.0064 0.0303
Schistosoma mansoni photoreceptor-specific nuclear receptor related 0.0102 0.0329 0.0574
Mycobacterium tuberculosis Phenyloxazoline synthase MbtB (phenyloxazoline synthetase) 0.0035 0.0081 0.0078
Trichomonas vaginalis dihydropyrimidine dehydrogenase, putative 0.0032 0.0068 0.0358
Loa Loa (eye worm) hypothetical protein 0.0043 0.0109 0.0401
Echinococcus multilocularis mothers against decapentaplegic 5 0.0018 0.0017 0.0003
Mycobacterium tuberculosis Probable membrane bound polyketide synthase Pks6 0.0045 0.0115 0.0117
Echinococcus granulosus nuclear receptor subfamily 1 group D 0.0054 0.015 0.0245
Echinococcus granulosus Smad4 0.0018 0.0017 0.0006
Plasmodium vivax M17 leucyl aminopeptidase, putative 0.0032 0.0068 0.0331
Loa Loa (eye worm) hypothetical protein 0.0086 0.0271 0.0996
Echinococcus granulosus L aminoadipate semialdehyde 0.0086 0.0271 0.0462
Loa Loa (eye worm) hypothetical protein 0.0019 0.0021 0.0076
Mycobacterium ulcerans hydroxymethylglutaryl-coenzyme a (HMG-CoA) reductase 0.0191 0.0661 1
Leishmania major geranylgeranyltransferase, putative 0.0026 0.0048 0.0528
Onchocerca volvulus 0.0017 0.0013 0.0071
Echinococcus multilocularis protein farnesyltransferase alpha subunit 0.0428 0.1546 0.1534
Mycobacterium ulcerans acyl-CoA synthetase 0.0026 0.0045 0.0378
Echinococcus granulosus Nuclear hormone receptor HR96 0.0048 0.0128 0.0206
Schistosoma mansoni norepinephrine/norepinephrine transporter 0.0043 0.0109 0.0179
Echinococcus multilocularis SAM and MBT domain containing protein 0.005 0.0135 0.0122
Trichomonas vaginalis conserved hypothetical protein 0.0032 0.0069 0.0365
Mycobacterium leprae PHENOLPTHIOCEROL SYNTHESIS TYPE-I POLYKETIDE SYNTHASE PPSB 0.0024 0.0038 0.0474
Mycobacterium leprae PROBABLE THIOESTERASE TESA 0.0025 0.0041 0.0569
Toxoplasma gondii 4'-phosphopantetheinyl transferase domain-containing protein 0.0024 0.0039 0.0294
Loa Loa (eye worm) hypothetical protein 0.0221 0.0772 0.2841
Trypanosoma cruzi ATP-dependent DEAD/H DNA helicase recQ, putative 0.0024 0.0037 0.0369
Trypanosoma cruzi apurinic/apyrimidinic endonuclease 0.0058 0.0167 0.2364
Echinococcus granulosus lamin 0.0093 0.0296 0.0508
Schistosoma mansoni protein tyrosine phosphatase 0.0017 0.0013 0.0008
Brugia malayi Pre-B cell enhancing factor precursor 0.0377 0.1353 0.4964
Loa Loa (eye worm) solute carrier family 6 member 4 0.0043 0.0109 0.0401
Echinococcus multilocularis thyroid hormone receptor alpha 0.0102 0.0329 0.0316
Echinococcus granulosus hepatocyte nuclear factor 4 alpha 0.0102 0.0329 0.0567
Plasmodium vivax AP endonuclease (DNA-[apurinic or apyrimidinic site] lyase), putative 0.0058 0.0167 0.0974
Loa Loa (eye worm) protein-tyrosine phosphatase 0.0017 0.0013 0.005
Echinococcus granulosus thyroid hormone receptor alpha 0.0048 0.0128 0.0206
Onchocerca volvulus Polycomb protein Sfmbt homolog 0.005 0.0135 0.2051
Echinococcus granulosus diuretic hormone 44 receptor GPRdih2 0.0157 0.0533 0.0932
Trypanosoma cruzi protein farnesyltransferase, putative 0.0098 0.0313 0.4621
Mycobacterium tuberculosis Inositol-1-monophosphatase SuhB 0.011 0.0358 0.0395
Trichomonas vaginalis protein farnesyltransferase beta subunit, putative 0.0026 0.0048 0.0223
Trichomonas vaginalis dihydroorotate dehydrogenase, putative 0.0036 0.0082 0.0444
Trypanosoma cruzi cytosolic leucyl aminopeptidase, putative 0.0019 0.002 0.0097
Schistosoma mansoni ran 0.0023 0.0034 0.0044
Echinococcus multilocularis COUP TF:Svp nuclear hormone receptor 0.0102 0.0329 0.0316
Loa Loa (eye worm) nuclear receptor nhr-7B 0.0048 0.0128 0.0472
Plasmodium vivax conserved Plasmodium protein, unknown function 0.0071 0.0214 0.1285
Echinococcus granulosus smad 0.0018 0.0017 0.0006
Echinococcus granulosus microtubule associated protein 2 0.1512 0.5584 1
Trichomonas vaginalis geranylgeranyl transferase type II beta subunit, putative 0.0098 0.0313 0.1953
Loa Loa (eye worm) nuclear hormone receptor 0.0048 0.0128 0.0472
Loa Loa (eye worm) hypothetical protein 0.0017 0.0013 0.005
Brugia malayi nuclear receptor NHR-88 0.0048 0.0128 0.044
Brugia malayi hypothetical protein 0.0017 0.0013 0.0016
Echinococcus multilocularis sodium:chloride dependent neurotransmitter 0.0043 0.0109 0.0096
Echinococcus granulosus geminin 0.0765 0.2801 0.5003
Loa Loa (eye worm) hypothetical protein 0.0019 0.0021 0.0076
Schistosoma mansoni inositol monophosphatase 0.0123 0.0406 0.0711
Loa Loa (eye worm) hypothetical protein 0.0026 0.0045 0.0165
Loa Loa (eye worm) hypothetical protein 0.0017 0.0013 0.005
Echinococcus multilocularis ATP dependent DNA helicase Q5 0.0024 0.0037 0.0024
Echinococcus granulosus guanine nucleotide binding protein Gs subunit 0.005 0.0134 0.0216
Brugia malayi hypothetical protein 0.0036 0.0082 0.027
Echinococcus multilocularis serotonin receptor 0.0032 0.0067 0.0054
Echinococcus granulosus sodium and chloride dependent glycine 0.0221 0.0772 0.1361
Plasmodium vivax protein prenyltransferase alpha subunit, putative 0.0134 0.045 0.283
Echinococcus granulosus biogenic amine 5HT receptor 0.0075 0.023 0.0389
Plasmodium falciparum AP endonuclease (DNA-[apurinic or apyrimidinic site] lyase), putative 0.0058 0.0167 0.0974
Echinococcus multilocularis isocitrate dehydrogenase 2 (NADP+) 0.0018 0.0018 0.0004
Onchocerca volvulus 0.0017 0.0013 0.0071
Mycobacterium ulcerans polyketide synthase 0.003 0.006 0.0615
Loa Loa (eye worm) GTP-binding regulatory protein Gs alpha-S chain 0.005 0.0134 0.0493
Trypanosoma brucei importin beta-1 subunit, putative 0.0031 0.0064 0.0781
Echinococcus granulosus nicotinamide phosphoribosyltransferase 0.0377 0.1353 0.2404
Brugia malayi GTP-binding regulatory protein Gs alpha-S chain, putative 0.005 0.0134 0.0461
Brugia malayi AMP-binding enzyme family protein 0.0026 0.0045 0.0132
Brugia malayi chromobox protein homolog 3 0.0046 0.0119 0.0407
Mycobacterium ulcerans Type I modular polyketide synthase 0.003 0.006 0.0615
Leishmania major trypanothione reductase 0.0038 0.0092 0.1217
Schistosoma mansoni retinoid-x-receptor (RXR) 0.0102 0.0329 0.0574
Brugia malayi Protein prenyltransferase alpha subunit repeat containing protein 0.0428 0.1546 0.5677
Echinococcus multilocularis Nuclear hormone receptor HR96 0.0048 0.0128 0.0115
Brugia malayi Hydroxymethylglutaryl-coenzyme A reductase family protein 0.0191 0.0661 0.2409
Trypanosoma cruzi Protein prenyltransferase alpha subunit repeat, putative 0.0134 0.045 0.6744
Loa Loa (eye worm) hypothetical protein 0.0428 0.1546 0.5691
Schistosoma mansoni aminoadipate-semialdehyde dehydrogenase 0.0086 0.0271 0.0469
Brugia malayi Protein-tyrosine phosphatase containing protein 0.0017 0.0013 0.0016
Toxoplasma gondii hypothetical protein 0.0134 0.045 0.4262
Toxoplasma gondii dihydroorotate dehydrogenase reveal, putative 0.0082 0.0255 0.2373
Echinococcus granulosus suppression of tumorigenicity 18 protein 0.0057 0.0161 0.0264
Loa Loa (eye worm) hypothetical protein 0.0046 0.0119 0.0439
Loa Loa (eye worm) hypothetical protein 0.0064 0.0188 0.0692
Echinococcus granulosus sodium and chloride dependent glycine 0.0221 0.0772 0.1361
Echinococcus granulosus NADP dependent isocitrate dehydrogenase 0.0018 0.0018 0.0008
Schistosoma mansoni amine GPCR 0.0039 0.0095 0.0155
Echinococcus multilocularis ATP dependent DNA helicase Q1 0.0024 0.0037 0.0024
Onchocerca volvulus 0.0017 0.0013 0.0071
Echinococcus multilocularis mitogen activated protein kinase 14 0.0043 0.0108 0.0095
Trichomonas vaginalis chromobox protein, putative 0.0049 0.0132 0.0774
Trichomonas vaginalis chromobox protein, putative 0.0081 0.0253 0.156
Trichomonas vaginalis nicotinate phosphoribosyltransferase, putative 0.007 0.0209 0.1278
Brugia malayi Protein-tyrosine phosphatase containing protein 0.0017 0.0013 0.0016
Echinococcus granulosus dihydropyrimidine dehydrogenase NADP 0.0036 0.0082 0.0122
Echinococcus granulosus aldehyde dehydrogenase mitochondrial 0.0065 0.0191 0.0319
Brugia malayi calcium-independent alpha-latrotoxin receptor 2, putative 0.0157 0.0533 0.1935
Onchocerca volvulus Heterochromatin protein 1 homolog 0.0049 0.0132 0.2004
Echinococcus multilocularis geminin 0.0765 0.2801 0.2791
Loa Loa (eye worm) intermediate filament protein 0.0093 0.0296 0.1091
Loa Loa (eye worm) MH2 domain-containing protein 0.0018 0.0017 0.0061
Loa Loa (eye worm) hypothetical protein 0.0048 0.0128 0.0472
Brugia malayi hypothetical protein 0.0043 0.0109 0.0369
Brugia malayi Protein-tyrosine phosphatase 0.0017 0.0013 0.0016
Mycobacterium ulcerans acyl-CoA synthetase 0.0026 0.0045 0.0378
Brugia malayi hypothetical protein 0.0054 0.015 0.052
Trypanosoma cruzi protein farnesyltransferase, putative 0.0098 0.0313 0.4621
Mycobacterium tuberculosis Probable aminopeptidase PepB 0.0032 0.0068 0.0064
Leishmania major importin beta-1 subunit, putative 0.0025 0.0042 0.0445
Echinococcus multilocularis laminin 0.0018 0.0016 0.0002
Mycobacterium ulcerans exodeoxyribonuclease III protein XthA 0.0058 0.0167 0.2278
Loa Loa (eye worm) thioredoxin reductase 0.0038 0.0092 0.034
Brugia malayi conserved hypotetical protein 0.0048 0.0128 0.044
Schistosoma mansoni NAALADASE L peptidase (M28 family) 0.0045 0.0117 0.0193
Brugia malayi Protein-tyrosine phosphatase 0.0017 0.0013 0.0016
Trypanosoma cruzi GTP-binding nuclear protein rtb2, putative 0.0023 0.0034 0.0312
Onchocerca volvulus 0.0017 0.0013 0.0071
Brugia malayi hypothetical protein 0.0122 0.0403 0.1455
Mycobacterium leprae PHENOLPTHIOCEROL SYNTHESIS TYPE-I POLYKETIDE SYNTHASE PPSC 0.0032 0.0067 0.1326
Brugia malayi Corticotropin releasing factor receptor 2 precursor, putative 0.0495 0.1794 0.6594
Plasmodium falciparum geranylgeranyl transferase type2 beta subunit, putative 0.0026 0.0048 0.0195
Toxoplasma gondii 4'-phosphopantetheinyl transferase superfamily protein 0.0024 0.0039 0.0294
Loa Loa (eye worm) protein-tyrosine phosphatase 0.0017 0.0013 0.005
Echinococcus granulosus TGF beta signal transducer SmadC 0.0018 0.0017 0.0006
Leishmania major GTP-binding protein, putative 0.0023 0.0034 0.0312
Loa Loa (eye worm) CMGC/MAPK/P38 protein kinase 0.0043 0.0108 0.0398
Echinococcus multilocularis mitogen activated protein kinase 14 0.0043 0.0108 0.0095
Trypanosoma cruzi geranylgeranyl transferase type II beta subunit, putative 0.0026 0.0048 0.0528
Schistosoma mansoni protein-tyrosine phosphatase n9 0.0017 0.0013 0.0008
Echinococcus granulosus endonuclease exonuclease phosphatase 0.0208 0.0726 0.1279
Echinococcus multilocularis smad 0.0018 0.0017 0.0003
Echinococcus multilocularis sodium and chloride dependent glycine 0.0221 0.0772 0.0759
Mycobacterium leprae possible inositol monophosphatase SubH (IMPase) (inositol-1-phosphatase) (I-1-Pase ). 0.011 0.0358 1
Schistosoma mansoni receptor protein tyrosine phosphatase n (ia2) 0.0017 0.0013 0.0008
Brugia malayi nuclear receptor subfamily 1, group D, member 1, putative 0.0048 0.0128 0.044
Loa Loa (eye worm) hypothetical protein 0.0102 0.0329 0.1212
Brugia malayi Sodium:neurotransmitter symporter family protein 0.0043 0.0109 0.0369
Echinococcus multilocularis uncharacterized sodium dependent transporter 0.0043 0.0109 0.0096
Mycobacterium tuberculosis Fatty-acid-AMP ligase FadD30 (fatty-acid-AMP synthetase) (fatty-acid-AMP synthase) 0.0019 0.0021 0.001
Echinococcus granulosus DNA apurinic or apyrimidinic site lyase 0.0058 0.0167 0.0275
Loa Loa (eye worm) hypothetical protein 0.0053 0.0148 0.0544
Mycobacterium tuberculosis Phenolpthiocerol synthesis type-I polyketide synthase PpsD 0.003 0.006 0.0055
Onchocerca volvulus 0.0017 0.0013 0.0071
Trypanosoma brucei mitogen-activated protein kinase 3, putative 0.0043 0.0108 0.1459
Loa Loa (eye worm) Sodium:neurotransmitter symporter family protein 0.0043 0.0109 0.0401
Echinococcus multilocularis histone acetyltransferase MYST2 0.0057 0.0161 0.0147
Loa Loa (eye worm) nuclear Hormone Receptor family member 0.0102 0.0329 0.1212
Brugia malayi protein-tyrosine phosphatase Lar-like precursor, putative 0.0017 0.0013 0.0016
Brugia malayi MH2 domain containing protein 0.0018 0.0017 0.0028
Brugia malayi steroid hormone receptor 0.0102 0.0329 0.1182
Loa Loa (eye worm) abnormal chemotaxis protein 14 0.0079 0.0242 0.0892
Toxoplasma gondii hypothetical protein 0.0043 0.0109 0.0966
Brugia malayi hypothetical protein 0.0181 0.0623 0.2267
Loa Loa (eye worm) hypothetical protein 0.0018 0.0016 0.0058
Trichomonas vaginalis chromobox protein, putative 0.0081 0.0253 0.156
Trypanosoma cruzi metallo-peptidase, Clan MF, Family M17, putative 0.0019 0.002 0.0097
Loa Loa (eye worm) hypothetical protein 0.0157 0.0533 0.1962
Giardia lamblia Rab geranylgeranyltransferase 0.0428 0.1546 1
Brugia malayi hypothetical protein 0.0742 0.2716 1
Trypanosoma cruzi nicotinate phosphoribosyltransferase, putative 0.007 0.0209 0.3025
Trichomonas vaginalis 3-hydroxy-3-methylglutaryl-coenzyme A reductase, putative 0.009 0.0283 0.176
Trypanosoma cruzi isocitrate dehydrogenase, putative 0.0018 0.0018 0.0067
Echinococcus multilocularis aldehyde dehydrogenase, mitochondrial 0.0065 0.0191 0.0178
Leishmania major ATP-dependent DEAD/H DNA helicase recQ, putative 0.0024 0.0037 0.0369
Loa Loa (eye worm) hypothetical protein 0.0181 0.0623 0.2293
Trypanosoma brucei Protein prenyltransferase alpha subunit repeat, putative 0.0134 0.045 0.6744
Schistosoma mansoni receptor tyrosine phosphatase type r2a 0.0017 0.0013 0.0008
Echinococcus multilocularis bloom syndrome protein 0.0024 0.0037 0.0024
Onchocerca volvulus 0.0093 0.0296 0.4679
Mycobacterium tuberculosis Probable dihydroorotate dehydrogenase PyrD 0.0082 0.0255 0.0277
Mycobacterium ulcerans Type I modular polyketide synthase 0.003 0.006 0.0615
Entamoeba histolytica hypothetical protein 0.0103 0.0332 0.2076
Schistosoma mansoni hypothetical protein 0.0157 0.0533 0.0939
Brugia malayi cytoplasmic intermediate filament protein 0.005 0.0135 0.0465
Schistosoma mansoni steroid hormone receptor ad4bp 0.0102 0.0329 0.0574
Trichomonas vaginalis importin beta-1, putative 0.0025 0.0042 0.0188
Loa Loa (eye worm) nucleolar RNA-associated protein alpha 0.033 0.1178 0.4337
Echinococcus multilocularis GPCR, family 2 0.0157 0.0533 0.052
Trichomonas vaginalis Importin beta-1 subunit, putative 0.0025 0.0042 0.0188
Giardia lamblia Rab geranylgeranyltransferase 0.0134 0.045 0.2851
Schistosoma mansoni ap endonuclease 0.0058 0.0167 0.0282
Brugia malayi Nuclear hormone receptor family member nhr-19 0.0102 0.0329 0.1182
Echinococcus multilocularis protein dispatched 1 0.0079 0.0242 0.0229
Loa Loa (eye worm) hypothetical protein 0.0017 0.0013 0.005
Loa Loa (eye worm) hypothetical protein 0.0017 0.0013 0.005
Trichomonas vaginalis geranylgeranyl transferase type I beta subunit, putative 0.0098 0.0313 0.1953
Mycobacterium tuberculosis Probable polyketide synthase Pks7 0.0032 0.0067 0.0063
Giardia lamblia Prenyltransferase 0.0098 0.0313 0.1953
Onchocerca volvulus 0.0017 0.0013 0.0071
Brugia malayi Nuclear hormone receptor family member nhr-19 0.0102 0.0329 0.1182
Loa Loa (eye worm) hypothetical protein 0.0043 0.011 0.0406
Trypanosoma cruzi hypothetical protein, conserved 0.0026 0.0048 0.0528
Echinococcus granulosus COUP TF:Svp nuclear hormone receptor 0.0102 0.0329 0.0567
Trypanosoma cruzi dihydroorotate dehydrogenase, putative 0.0082 0.0255 0.3725
Loa Loa (eye worm) steroid hormone receptor 0.0102 0.0329 0.1212
Brugia malayi Protein-tyrosine phosphatase 1 0.0017 0.0013 0.0016
Schistosoma mansoni receptor protein tyrosine phosphatase 0.0017 0.0013 0.0008
Trichomonas vaginalis Importin beta-1 subunit, putative 0.0025 0.0042 0.0188
Brugia malayi Latrophilin receptor protein 2 0.0157 0.0533 0.1935
Echinococcus granulosus Nuclear hormone receptor family member nhr 41 0.0102 0.0329 0.0567
Toxoplasma gondii Rab geranylgeranyl transferase type II beta subunit, putative 0.0026 0.0048 0.0373
Plasmodium vivax thioredoxin reductase, putative 0.0038 0.0092 0.0488
Schistosoma mansoni rab geranylgeranyl transferase alpha subunit 0.0134 0.045 0.0791
Echinococcus granulosus intermediate filament protein 0.0093 0.0296 0.0508
Trichomonas vaginalis dihydroorotate dehydrogenase, putative 0.0032 0.0068 0.0358
Echinococcus multilocularis mitogen activated protein kinase 11 0.0043 0.0108 0.0095
Trichomonas vaginalis conserved hypothetical protein 0.0079 0.0242 0.1493
Trypanosoma cruzi protein farnesyltransferase alpha subunit, putative 0.0134 0.045 0.6744
Brugia malayi Protein-tyrosine phosphatase containing protein 0.0017 0.0013 0.0016
Entamoeba histolytica geranylgeranyl transferase beta subunit 0.0026 0.0048 0.0223
Brugia malayi Protein-tyrosine phosphatase containing protein 0.0017 0.0013 0.0016
Loa Loa (eye worm) hypothetical protein 0.0023 0.0033 0.0123
Schistosoma mansoni inositol monophosphatase 0.0123 0.0406 0.0711
Schistosoma mansoni chromobox protein 0.0081 0.0253 0.0437
Loa Loa (eye worm) hypothetical protein 0.0026 0.0045 0.0165
Trichomonas vaginalis conserved hypothetical protein 0.0032 0.0069 0.0365
Chlamydia trachomatis holo [acyl-carrier protein] synthase 0.0024 0.0039 0.2126
Echinococcus multilocularis protein prenyltransferase alpha subunit 0.0134 0.045 0.0437
Toxoplasma gondii Sodium:neurotransmitter symporter family protein 0.0043 0.0109 0.0966
Echinococcus granulosus ecdysone induced protein 78C 0.0102 0.0329 0.0567
Brugia malayi hypothetical protein 0.0017 0.0013 0.0016
Onchocerca volvulus 0.0017 0.0013 0.0071
Mycobacterium tuberculosis Probable exodeoxyribonuclease III protein XthA (exonuclease III) (EXO III) (AP endonuclease VI) 0.0058 0.0167 0.0176
Echinococcus multilocularis nuclear receptor nhr 48 0.0048 0.0128 0.0115
Loa Loa (eye worm) nuclear hormone receptor family member nhr-14 0.0102 0.0329 0.1212
Loa Loa (eye worm) prenyltransferase and squalene oxidase repeat family protein 0.0098 0.0313 0.1152
Echinococcus multilocularis TGF beta signal transducer SmadC 0.0018 0.0017 0.0003
Echinococcus multilocularis hydroxymethylglutaryl coenzyme A reductase 0.0191 0.0661 0.0649
Brugia malayi Protein-tyrosine phosphatase containing protein 0.0017 0.0013 0.0016
Brugia malayi ATP-dependent DNA helicase, RecQ family protein 0.0024 0.0037 0.0104
Trypanosoma cruzi lanosterol synthase, putative 0.0097 0.031 0.4573
Echinococcus granulosus ATP dependent DNA helicase Q5 0.0024 0.0037 0.0043
Mycobacterium ulcerans long-chain fatty-acid CoA ligase 0.0026 0.0045 0.0378
Echinococcus multilocularis Nuclear hormone receptor family member nhr 41 0.0102 0.0329 0.0316
Echinococcus multilocularis chromobox protein 1 0.0081 0.0253 0.0239
Loa Loa (eye worm) nuclear hormone receptor family member nhr-31 0.0102 0.0329 0.1212
Trypanosoma cruzi GTP-binding nuclear protein rtb2, putative 0.0023 0.0034 0.0312
Loa Loa (eye worm) hypothetical protein 0.0191 0.0661 0.2434
Schistosoma mansoni hypothetical protein 0.033 0.1178 0.2097
Schistosoma mansoni RAR-like nuclear receptor 0.0102 0.0329 0.0574
Echinococcus multilocularis diuretic hormone 44 receptor GPRdih2 0.0157 0.0533 0.052
Mycobacterium tuberculosis Probable fatty-acid-CoA ligase FadD3 (fatty-acid-CoA synthetase) (fatty-acid-CoA synthase) 0.0018 0.0017 0.0005
Echinococcus granulosus thioredoxin glutathione reductase 0.0039 0.0094 0.0145
Schistosoma mansoni hypothetical protein 0.0151 0.0513 0.0904
Mycobacterium ulcerans leucyl aminopeptidase 0.0032 0.0068 0.0745
Loa Loa (eye worm) hypothetical protein 0.0017 0.0013 0.005
Loa Loa (eye worm) hypothetical protein 0.0742 0.2716 1
Schistosoma mansoni smad1 5 8 and 0.0018 0.0017 0.0014
Trichomonas vaginalis protein farnesyltransferase alpha subunit, putative 0.0428 0.1546 1
Schistosoma mansoni hypothetical protein 0.0157 0.0533 0.0939
Echinococcus granulosus Nuclear hormone receptor HR96 0.0048 0.0128 0.0206
Mycobacterium tuberculosis Probable fatty-acid-CoA ligase FadD35 (fatty-acid-CoA synthetase) (fatty-acid-CoA synthase) 0.0018 0.0017 0.0005
Brugia malayi Protein-tyrosine phosphatase containing protein 0.0017 0.0013 0.0016
Schistosoma mansoni nicotinate phosphoribosyltransferase related pre-B cell enhancing factor 0.007 0.0209 0.0359
Echinococcus granulosus protein prenyltransferase alpha subunit 0.0134 0.045 0.0784
Brugia malayi latrophilin 2 splice variant baaae 0.0338 0.121 0.4438
Entamoeba histolytica myo-inositol monophosphatase, putative 0.0123 0.0406 0.256
Loa Loa (eye worm) hypothetical protein 0.0057 0.0161 0.0592
Plasmodium vivax dihydroorotate dehydrogenase, mitochondrial precursor, putative 0.0082 0.0255 0.1551
Echinococcus multilocularis snurportin 1 0.033 0.1178 0.1166
Onchocerca volvulus Steroid hormone receptor family member cnr14 homolog 0.0102 0.0329 0.5214
Trypanosoma brucei protein farnesyltransferase beta subunit 0.0098 0.0313 0.4621
Brugia malayi Nuclear hormone receptor-like 1 0.0102 0.0329 0.1182
Trypanosoma cruzi dihydroorotate dehydrogenase, putative 0.0082 0.0255 0.3725
Loa Loa (eye worm) hypothetical protein 0.0047 0.0123 0.0453
Toxoplasma gondii ATP-dependent DNA helicase, RecQ family protein 0.0024 0.0037 0.0274
Leishmania major myo-inositol-1(or 4)-monophosphatase 1, putative 0.0123 0.0406 0.6057
Loa Loa (eye worm) protein-tyrosine-phosphatase 0.0017 0.0013 0.005
Loa Loa (eye worm) hypothetical protein 0.0026 0.0045 0.0165
Loa Loa (eye worm) hypothetical protein 0.0043 0.0109 0.0401
Loa Loa (eye worm) hypothetical protein 0.0043 0.011 0.0406
Onchocerca volvulus 0.0035 0.0081 0.1169
Loa Loa (eye worm) exodeoxyribonuclease III family protein 0.0058 0.0167 0.0613
Trichomonas vaginalis protein farnesyltransferase alpha subunit/RAB geranylgeranyl transferase alpha subunit, putative 0.0294 0.1044 0.6728
Schistosoma mansoni receptor tyrosine phosphatase type r2a 0.0017 0.0013 0.0008
Brugia malayi Fibulin-1 precursor 0.0018 0.0016 0.0025
Entamoeba histolytica hypothetical protein 0.0024 0.0039 0.0169
Onchocerca volvulus 0.0048 0.0128 0.1942
Schistosoma mansoni hypothetical protein 0.0157 0.0533 0.0939
Brugia malayi Nuclear hormone receptor family member nhr-40 0.0102 0.0329 0.1182
Schistosoma mansoni importin beta-1 0.0031 0.0064 0.0099
Loa Loa (eye worm) hypothetical protein 0.0051 0.0139 0.0513
Loa Loa (eye worm) hypothetical protein 0.0017 0.0013 0.005
Mycobacterium leprae conserved hypothetical protein 0.0024 0.0039 0.0508
Loa Loa (eye worm) hypothetical protein 0.0054 0.015 0.0551
Loa Loa (eye worm) hypothetical protein 0.0043 0.0109 0.0401
Mycobacterium tuberculosis Possible exported protein 0.2368 0.8776 1
Schistosoma mansoni protein tyrosine phosphatase 0.0017 0.0013 0.0008
Echinococcus multilocularis fibrillin 1 0.0023 0.0033 0.002
Echinococcus granulosus chromobox protein 1 0.0081 0.0253 0.0429
Schistosoma mansoni ap endonuclease 0.0058 0.0167 0.0282
Brugia malayi Protein-tyrosine phosphatase containing protein 0.0017 0.0013 0.0016
Echinococcus multilocularis integrin beta 2 0.0109 0.0355 0.0342
Treponema pallidum exodeoxyribonuclease (exoA) 0.0058 0.0167 0.7481
Brugia malayi Protein-tyrosine phosphatase containing protein 0.0017 0.0013 0.0016
Echinococcus multilocularis Rab geranylgeranyltransferase, beta subunit 0.0026 0.0048 0.0034
Trichomonas vaginalis geranylgeranyl transferase type beta subunit, putative 0.0098 0.0313 0.1953
Plasmodium falciparum glutathione reductase 0.0038 0.0092 0.0488
Brugia malayi orphan nuclear receptor NR2E1 0.0048 0.0128 0.044
Entamoeba histolytica protein farnesyltransferase alpha subunit, putative 0.0428 0.1546 1
Echinococcus granulosus geranylgeranyl transferase type 2 subunit alpha 0.0134 0.045 0.0784
Brugia malayi Protein-tyrosine phosphatase containing protein 0.0017 0.0013 0.0016
Entamoeba histolytica Ran family GTPase 0.0023 0.0034 0.0132
Brugia malayi Calcium binding EGF domain containing protein 0.0018 0.0016 0.0025
Brugia malayi RNA, U transporter 1 0.0088 0.0276 0.0987
Brugia malayi intermediate filament protein 0.0093 0.0296 0.1061
Onchocerca volvulus 0.0017 0.0013 0.0071
Brugia malayi tailless protein 0.0048 0.0128 0.044
Brugia malayi ecdysteroid receptor 0.0102 0.0329 0.1182
Mycobacterium tuberculosis Probable membrane NADH dehydrogenase NdhA 0.0088 0.0276 0.0301
Leishmania major 4-coumarate:coa ligase-like protein 0.0026 0.0045 0.0485
Plasmodium falciparum protein farnesyltransferase subunit beta 0.0098 0.0313 0.1931
Loa Loa (eye worm) hypothetical protein 0.0017 0.0013 0.005
Trypanosoma cruzi mitogen-activated protein kinase 3, putative 0.0043 0.0108 0.1459
Onchocerca volvulus Protein ultraspiracle homolog 0.0102 0.0329 0.5214
Toxoplasma gondii beta-ketoacyl synthase, N-terminal domain-containing protein 0.0019 0.0021 0.0116
Schistosoma mansoni nuclear hormone receptor 0.0048 0.0128 0.0214
Toxoplasma gondii isocitrate dehydrogenase 0.0018 0.0018 0.0085
Brugia malayi Protein-tyrosine phosphatase containing protein 0.0017 0.0013 0.0016
Mycobacterium tuberculosis Polyketide synthase Pks2 0.0029 0.0057 0.0051
Trypanosoma brucei inositol-1(or 4)-monophosphatase 1, putative 0.0123 0.0406 0.6057
Echinococcus granulosus mitogen activated protein kinase 14 0.0043 0.0108 0.017
Wolbachia endosymbiont of Brugia malayi leucyl aminopeptidase 0.0032 0.0068 0.079
Loa Loa (eye worm) hypothetical protein 0.0032 0.0067 0.0248
Plasmodium falciparum protein farnesyltransferase subunit alpha 0.0428 0.1546 1
Schistosoma mansoni patched 1 0.0079 0.0242 0.0418
Plasmodium falciparum GTP-binding nuclear protein RAN/TC4 0.0023 0.0034 0.0104
Schistosoma mansoni intermediate filament proteins 0.0093 0.0296 0.0515
Trichomonas vaginalis protein farnesyltransferase beta subunit, putative 0.0026 0.0048 0.0223
Brugia malayi Sodium:neurotransmitter symporter family protein 0.0043 0.0109 0.0369
Schistosoma mansoni hypothetical protein 0.0765 0.2801 0.5007
Schistosoma mansoni ran 0.0023 0.0034 0.0044
Brugia malayi Nuclear hormone receptor family member nhr-25 0.0102 0.0329 0.1182
Brugia malayi Protein-tyrosine phosphatase containing protein 0.0017 0.0013 0.0016
Loa Loa (eye worm) protein-tyrosine phosphatase 0.0017 0.0013 0.005
Mycobacterium tuberculosis holo-[acyl-carrier protein] synthase AcpS (holo-ACP synthase) (CoA:APO-[ACP]pantetheinephosphotransferase) (CoA:APO-[acyl-carrie 0.0024 0.0039 0.0031
Schistosoma mansoni smad 0.0018 0.0017 0.0014
Onchocerca volvulus 0.0017 0.0013 0.0071
Brugia malayi Nuclear hormone receptor family member nhr-3 0.0102 0.0329 0.1182
Mycobacterium tuberculosis NADPH-dependent mycothiol reductase Mtr 0.0038 0.0092 0.0092
Echinococcus granulosus sodium dependent neurotransmitter transporter 0.0043 0.0109 0.0172
Trichomonas vaginalis geranylgeranyl transferase type II beta subunit, putative 0.0098 0.0313 0.1953
Schistosoma mansoni norepinephrine/norepinephrine transporter 0.0043 0.0109 0.0179
Mycobacterium tuberculosis Probable conserved lipoprotein LpqF 0.002 0.0023 0.0012
Brugia malayi aminoadipate-semialdehyde dehydrogenase-phosphopantetheinyl transferase 0.0086 0.0271 0.0966
Loa Loa (eye worm) hypothetical protein 0.0017 0.0013 0.005
Echinococcus granulosus mothers against decapentaplegic 5 0.0018 0.0017 0.0006
Trypanosoma brucei geranylgeranyl transferase type II beta subunit, putative 0.0026 0.0048 0.0528
Plasmodium falciparum transporter, putative 0.0043 0.0109 0.0597
Mycobacterium leprae PROBABLE FATTY-ACID-CoA LIGASE FADD2 (FATTY-ACID-CoA SYNTHETASE) (FATTY-ACID-CoA SYNTHASE) 0.0026 0.0045 0.067
Loa Loa (eye worm) hypothetical protein 0.0043 0.0109 0.0401
Schistosoma mansoni sodium/chloride dependent neurotransmitter transporter 0.0043 0.0109 0.0179
Onchocerca volvulus 0.0017 0.0013 0.0071
Loa Loa (eye worm) hypothetical protein 0.0031 0.0064 0.0236
Brugia malayi Smad1 0.0018 0.0017 0.0028
Echinococcus granulosus uncharacterized sodium dependent transporter 0.0043 0.0109 0.0172
Echinococcus granulosus sodium:chloride dependent neurotransmitter 0.0043 0.0109 0.0172
Schistosoma mansoni aldehyde dehydrogenase 0.0065 0.0191 0.0327
Schistosoma mansoni DNA helicase recq5 0.0024 0.0037 0.0051
Plasmodium vivax importin-beta 2, putative 0.0031 0.0064 0.0303
Leishmania major lanosterol synthase, putative 0.007 0.0211 0.3049
Schistosoma mansoni integrin beta subunit 0.0087 0.0272 0.0471
Mycobacterium tuberculosis Probable reductase 0.0088 0.0276 0.0301
Echinococcus multilocularis suppression of tumorigenicity 18 protein 0.0057 0.0161 0.0147
Entamoeba histolytica Rab geranylgeranyltransferase beta subunit, putative 0.0026 0.0048 0.0223
Schistosoma mansoni receptor tyrosine phosphatase type r2a 0.0017 0.0013 0.0008
Entamoeba histolytica exodeoxyribonuclease III, putative 0.0058 0.0167 0.0999
Onchocerca volvulus 0.0017 0.0013 0.0071
Mycobacterium ulcerans class a beta-lactamase, BlaC 0.0041 0.0103 0.129
Brugia malayi C2-HC type zinc finger protein C.e-MyT1 0.0057 0.0161 0.056
Mycobacterium ulcerans lipoprotein LpqF 0.002 0.0023 0.0038
Echinococcus multilocularis nuclear receptor 2DBD gamma 0.0102 0.0329 0.0316
Mycobacterium ulcerans phenolpthiocerol synthesis type-I polyketide synthase PpsC 0.0032 0.0067 0.0722
Brugia malayi nuclear receptor NHR-67 0.0048 0.0128 0.044
Brugia malayi hypothetical protein 0.0048 0.0128 0.044
Loa Loa (eye worm) pre-B cell enhancing factor 0.0377 0.1353 0.4981
Schistosoma mansoni Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) 0.005 0.0134 0.0224
Schistosoma mansoni biogenic amine (5HT) receptor 0.0075 0.023 0.0396
Schistosoma mansoni nuclear hormone receptor superfamily protein-related 0.0317 0.1131 0.2012
Schistosoma mansoni sodium-dependent amino acid transporter 0.0043 0.0109 0.0179
Loa Loa (eye worm) hypothetical protein 0.0017 0.0013 0.005
Echinococcus granulosus cadherin EGF LAG seven pass G type receptor 0.0157 0.0533 0.0932
Echinococcus granulosus bloom syndrome protein 0.0024 0.0037 0.0043
Trypanosoma brucei protein farnesyltransferase alpha subunit, putative 0.0134 0.045 0.6744
Echinococcus multilocularis tm gpcr rhodopsin gpcr rhodopsin superfamily 0.0153 0.0519 0.0506
Mycobacterium ulcerans extragenic suppressor protein SuhB 0.0123 0.0406 0.6013
Brugia malayi Protein-tyrosine phosphatase containing protein 0.0017 0.0013 0.0016
Echinococcus multilocularis arachidonate 5 lipoxygenase 0.0037 0.0086 0.0073
Echinococcus granulosus GTP binding nuclear protein Ran 0.0023 0.0034 0.0036
Echinococcus multilocularis dihydropyrimidine dehydrogenase (NADP+) 0.0036 0.0082 0.0068
Onchocerca volvulus 0.0017 0.0013 0.0071
Schistosoma mansoni sodium-dependent neurotransmitter transporter 0.0043 0.0109 0.0179
Echinococcus multilocularis GTP binding nuclear protein Ran 0.0023 0.0034 0.002
Onchocerca volvulus 0.0017 0.0013 0.0071
Schistosoma mansoni hydroxymethylglutaryl-CoA reductase (NADPH) 0.0191 0.0661 0.117
Echinococcus multilocularis nuclear receptor subfamily 1 group D 0.0054 0.015 0.0136
Brugia malayi Protein-tyrosine phosphatase containing protein 0.0017 0.0013 0.0016
Schistosoma mansoni myelin transcription factor 1 myt1 0.0057 0.0161 0.0272
Loa Loa (eye worm) isocitrate dehydrogenase 0.0018 0.0018 0.0066
Toxoplasma gondii leucyl aminopeptidase LAP 0.0032 0.0068 0.0573
Loa Loa (eye worm) prenyltransferase and squalene oxidase repeat family protein 0.0026 0.0048 0.0175
Trypanosoma brucei apurinic/apyrimidinic endonuclease, putative 0.0058 0.0167 0.2364
Onchocerca volvulus 0.0181 0.0623 1
Loa Loa (eye worm) AMP-binding enzyme family protein 0.0035 0.0081 0.0298
Schistosoma mansoni sex comb on midleg homolog 0.005 0.0135 0.0226
Loa Loa (eye worm) nuclear receptor NHR-67 0.0048 0.0128 0.0472
Trypanosoma cruzi apurinic/apyrimidinic endonuclease, putative 0.0058 0.0167 0.2364
Loa Loa (eye worm) MH2 domain-containing protein 0.0267 0.0943 0.3473
Trichomonas vaginalis dihydroorotate dehydrogenase, putative 0.0032 0.0068 0.0358
Schistosoma mansoni microtubule-associated protein tau 0.1512 0.5584 1
Onchocerca volvulus 0.0093 0.0296 0.4679
Mycobacterium tuberculosis Probable nitrite reductase [NAD(P)H] large subunit [FAD flavoprotein] NirB 0.0088 0.0276 0.0301
Schistosoma mansoni receptor tyrosine phosphatase type r2a 0.0017 0.0013 0.0008
Schistosoma mansoni Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) 0.005 0.0134 0.0224
Echinococcus multilocularis mitogen activated protein kinase 11 0.0043 0.0108 0.0095
Brugia malayi Dihydroorotate dehydrogenase, mitochondrial precursor, putative 0.0082 0.0255 0.0907
Mycobacterium ulcerans Type I modular polyketide synthase 0.003 0.006 0.0615
Loa Loa (eye worm) nuclear hormone receptor family member nhr-41 0.0102 0.0329 0.1212
Toxoplasma gondii aldehyde dehydrogenase 0.0065 0.0191 0.1762
Echinococcus multilocularis hepatocyte nuclear factor 4 alpha 0.0102 0.0329 0.0316
Brugia malayi Calcitonin receptor-like protein seb-1 0.0495 0.1794 0.6594
Toxoplasma gondii prenyltransferase and squalene oxidase repeat-containing protein 0.0098 0.0313 0.2934
Mycobacterium ulcerans phenolpthiocerol synthesis type-I polyketide synthase PpsE 0.002 0.0022 0.0027
Loa Loa (eye worm) protein-tyrosine phosphatase 0.0017 0.0013 0.005
Brugia malayi ATP-dependent DNA helicase, RecQ family protein 0.0024 0.0037 0.0104
Echinococcus multilocularis polycomb protein SCMH1 0.005 0.0135 0.0122
Loa Loa (eye worm) hypothetical protein 0.0017 0.0013 0.005
Toxoplasma gondii HEAT repeat-containing protein 0.0031 0.0064 0.0532
Brugia malayi Importin beta-1 subunit 0.0031 0.0064 0.0203
Loa Loa (eye worm) fibronectin type III domain-containing protein 0.0017 0.0013 0.005
Loa Loa (eye worm) pigment dispersing factor receptor c 0.0495 0.1794 0.6606
Brugia malayi ecdysone receptor 0.0048 0.0128 0.044
Plasmodium falciparum amino acid transporter, putative 0.0043 0.0109 0.0597
Plasmodium falciparum ADP-dependent DNA helicase RecQ 0.0024 0.0037 0.0128
Entamoeba histolytica acyl-coA synthetase, putative 0.0026 0.0045 0.0205
Loa Loa (eye worm) intermediate filament tail domain-containing protein 0.0093 0.0296 0.1091
Toxoplasma gondii hypothetical protein 0.0294 0.1044 1
Toxoplasma gondii GTP-binding nuclear protein ran/tc4 0.0023 0.0034 0.0239
Schistosoma mansoni protein tyrosine phosphatase non-receptor type nt1 0.0017 0.0013 0.0008
Brugia malayi Protein prenyltransferase alpha subunit repeat containing protein 0.0134 0.045 0.163
Loa Loa (eye worm) prenyltransferase alpha subunit repeat containing protein 0.0428 0.1546 0.5691
Schistosoma mansoni lamin 0.0093 0.0296 0.0515
Echinococcus multilocularis retinoic acid receptor rxr beta a retinoic acid receptor rxr alpha a retinoic acid receptor rxr alpha 0.0048 0.0128 0.0115
Brugia malayi CHE-14 protein 0.0079 0.0242 0.0861
Entamoeba histolytica hypothetical protein 0.0036 0.0082 0.0449
Schistosoma mansoni dihydroorotate dehydrogenase 0.0082 0.0255 0.0441
Trichomonas vaginalis geranylgeranyl transferase type I beta subunit, putative 0.0026 0.0048 0.0223
Treponema pallidum nicotinate phosphoribosyltransferase 0.007 0.0209 1
Giardia lamblia Endonuclease/Exonuclease/phosphatase 0.0058 0.0167 0.0999
Loa Loa (eye worm) dual specificity protein phosphatase CDC14B 0.0017 0.0013 0.005
Loa Loa (eye worm) protein-tyrosine phosphatase 0.0017 0.0013 0.005
Leishmania major protein farnesyltransferase alpha subunit, putative 0.0134 0.045 0.6744
Loa Loa (eye worm) hypothetical protein 0.0017 0.0013 0.005
Loa Loa (eye worm) serotonin transporter b 0.0043 0.0109 0.0401
Trypanosoma brucei isocitrate dehydrogenase, putative 0.0018 0.0018 0.0067
Loa Loa (eye worm) protein tyrosine phosphatase 0.0017 0.0013 0.005
Trypanosoma brucei Protein prenyltransferase alpha subunit repeat, putative 0.0134 0.045 0.6744
Trichomonas vaginalis conserved hypothetical protein 0.0046 0.0119 0.069
Schistosoma mansoni retinoic acid receptor RXR 0.0102 0.0329 0.0574
Plasmodium falciparum ATP-dependent DNA helicase Q1 0.0024 0.0037 0.0128
Brugia malayi Intermediate filament tail domain containing protein 0.0093 0.0296 0.1061
Echinococcus multilocularis cadherin EGF LAG seven pass G type receptor 0.0157 0.0533 0.052
Mycobacterium tuberculosis Probable fatty-acid-CoA ligase FadD5 (fatty-acid-CoA synthetase) (fatty-acid-CoA synthase) 0.0018 0.0017 0.0005
Echinococcus granulosus leucine aminopeptidase protein 0.0032 0.0068 0.0099
Mycobacterium tuberculosis Probable chain -fatty-acid-CoA ligase FadD13 (fatty-acyl-CoA synthetase) 0.0026 0.0045 0.0037
Onchocerca volvulus 0.0017 0.0013 0.0071
Loa Loa (eye worm) hypothetical protein 0.0122 0.0403 0.1484
Schistosoma mansoni nuclear hormone receptor 0.0048 0.0128 0.0214
Loa Loa (eye worm) hypothetical protein 0.0016 0.0009 0.0033
Onchocerca volvulus 0.0043 0.0109 0.1629
Loa Loa (eye worm) hypothetical protein 0.0048 0.0128 0.0472
Trypanosoma cruzi 3-hydroxy-3-methylglutaryl-CoA reductase, putative 0.0191 0.0661 1
Schistosoma mansoni TGF-beta signal transducer Smad2 0.0018 0.0017 0.0014
Loa Loa (eye worm) protein-tyrosine phosphatase 0.0017 0.0013 0.005
Brugia malayi Protein-tyrosine phosphatase containing protein 0.0017 0.0013 0.0016
Schistosoma mansoni protein farnesyltransferase alpha subunit 0.0428 0.1546 0.2756
Mycobacterium ulcerans phenolpthiocerol synthesis type-I polyketide synthase PpsA 0.0024 0.0038 0.0276
Schistosoma mansoni DNA helicase recq1 0.0024 0.0037 0.0051
Mycobacterium tuberculosis Probable fatty-acid-CoA ligase FadD2 (fatty-acid-CoA synthetase) (fatty-acid-CoA synthase) 0.0026 0.0045 0.0037
Mycobacterium leprae DIHYDROLIPOAMIDE DEHYDROGENASE LPD (LIPOAMIDE REDUCTASE (NADH)) (LIPOYL DEHYDROGENASE) (DIHYDROLIPOYL DEHYDROGENASE) (DIAPHORASE 0.0097 0.0312 0.8645
Brugia malayi Serotonin receptor 0.009 0.0283 0.1013
Echinococcus multilocularis NADP dependent isocitrate dehydrogenase 0.0018 0.0018 0.0004
Schistosoma mansoni smad1 5 8 and 0.0018 0.0017 0.0014
Trypanosoma brucei importin beta-1 subunit, putative 0.0031 0.0064 0.0781
Onchocerca volvulus Nuclear receptor subfamily 6 group A member 1 homolog 0.0048 0.0128 0.1942
Loa Loa (eye worm) hypothetical protein 0.0054 0.015 0.0551
Brugia malayi Protein-tyrosine phosphatase containing protein 0.0017 0.0013 0.0016
Loa Loa (eye worm) hypothetical protein 0.0091 0.029 0.1067
Schistosoma mansoni thyroid hormone receptor 0.0102 0.0329 0.0574
Leishmania major phosphopantetheinyl transferase-like protein 0.0024 0.0039 0.0401
Schistosoma mansoni protein-tyrosine phosphatase non-receptor type nt5 0.0017 0.0013 0.0008
Brugia malayi Protein-tyrosine phosphatase containing protein 0.0017 0.0013 0.0016
Echinococcus multilocularis sodium and chloride dependent glycine 0.0221 0.0772 0.0759
Brugia malayi nuclear receptor RXR 0.0048 0.0128 0.044
Schistosoma mansoni niemann-pick C1 (NPC1) 0.0079 0.0242 0.0418
Schistosoma mansoni hypothetical protein 0.0315 0.1123 0.1999
Loa Loa (eye worm) norepinephrine transporter 0.0043 0.0109 0.0401
Onchocerca volvulus Huntingtin homolog 0.0122 0.0403 0.6418
Schistosoma mansoni rgs-gaip interacting protein gipc 0.0017 0.0013 0.0008
Plasmodium vivax acyl-CoA synthetase, putative 0.0019 0.0021 0.0018
Schistosoma mansoni nuclear receptor 0.0048 0.0128 0.0214
Schistosoma mansoni lipoxygenase 0.0037 0.0086 0.0138
Echinococcus granulosus integrin beta 2 0.0109 0.0355 0.0613
Mycobacterium tuberculosis Probable polyketide synthase Pks1 0.0021 0.0029 0.0019
Echinococcus granulosus lamin dm0 0.0093 0.0296 0.0508
Loa Loa (eye worm) hypothetical protein 0.0017 0.0013 0.005
Loa Loa (eye worm) protein-tyrosine phosphatase 0.0017 0.0013 0.005
Giardia lamblia Rab geranylgeranyltransferase 0.0026 0.0048 0.0223
Loa Loa (eye worm) nuclear hormone receptor family member nhr-40 0.0102 0.0329 0.1212
Leishmania major 3-hydroxy-3-methylglutaryl-CoA reductase 0.0191 0.0661 1
Trypanosoma cruzi dihydroorotate dehydrogenase, putative 0.0032 0.0068 0.0848
Brugia malayi exodeoxyribonuclease III family protein 0.0058 0.0167 0.0582
Schistosoma mansoni biogenic amine (5HT) receptor 0.0032 0.0067 0.0104
Brugia malayi Dual specificity protein phosphatase CDC14B 0.0017 0.0013 0.0016
Giardia lamblia 3-hydroxy-3-methylglutaryl-coenzyme A reductase 0.009 0.0283 0.176
Loa Loa (eye worm) protein-tyrosine phosphatase 0.0017 0.0013 0.005
Onchocerca volvulus 0.005 0.0135 0.2051
Plasmodium vivax hypothetical protein, conserved 0.0043 0.0109 0.0597
Trypanosoma brucei hypothetical protein, conserved 0.0024 0.0039 0.0401
Mycobacterium tuberculosis Class a beta-lactamase BlaC 0.0041 0.0103 0.0104
Mycobacterium ulcerans aldehyde dehydrogenase 0.0065 0.0191 0.2666
Plasmodium vivax farnesyltransferase beta subunit, putative 0.0098 0.0313 0.1931
Leishmania major dihydroorotate dehydrogenase 0.0082 0.0255 0.3725
Leishmania major apurinic/apyrimidinic endonuclease-redox protein 0.0058 0.0167 0.2364
Plasmodium falciparum geranylgeranyltransferase, putative 0.0026 0.0048 0.0195
Onchocerca volvulus 0.0017 0.0013 0.0071
Schistosoma mansoni nuclear receptor nhr-48 0.0048 0.0128 0.0214
Mycobacterium leprae PROBABLE CONSERVED LIPOPROTEIN LPQF 0.002 0.0023 0.0019
Echinococcus granulosus survival motor neuron protein 1 0.0742 0.2716 0.4851
Echinococcus granulosus dihydropyrimidine dehydrogenase NADP 0.0036 0.0082 0.0122
Loa Loa (eye worm) hypothetical protein 0.0026 0.0048 0.0175
Loa Loa (eye worm) hypothetical protein 0.007 0.0211 0.0778
Mycobacterium ulcerans aldehyde dehydrogenase 0.0065 0.0191 0.2666
Trichomonas vaginalis myo inositol monophosphatase, putative 0.0123 0.0406 0.256
Mycobacterium tuberculosis Probable fatty-acid-CoA ligase FadD7 (fatty-acid-CoA synthetase) (fatty-acid-CoA synthase) 0.0018 0.0017 0.0005
Loa Loa (eye worm) hypothetical protein 0.0043 0.0109 0.0401
Loa Loa (eye worm) hypothetical protein 0.0054 0.015 0.0551
Mycobacterium tuberculosis Putative ferredoxin reductase 0.0088 0.0276 0.0301
Trichomonas vaginalis ran, putative 0.0023 0.0034 0.0132
Mycobacterium ulcerans polyketide synthase 0.0032 0.0067 0.0722
Schistosoma mansoni Tr4/Tr2 (homologue) 0.0102 0.0329 0.0574
Onchocerca volvulus 0.0017 0.0013 0.0071
Toxoplasma gondii prenyltransferase and squalene oxidase repeat-containing protein 0.0026 0.0048 0.0373
Loa Loa (eye worm) hypothetical protein 0.0048 0.0128 0.0472
Mycobacterium tuberculosis Probable isocitrate dehydrogenase [NADP] Icd1 (oxalosuccinate decarboxylase) (IDH) (NADP+-specific ICDH) (IDP) 0.0018 0.0018 0.0007
Brugia malayi hypothetical protein 0.0017 0.0013 0.0016
Treponema pallidum sodium- and chloride- dependent transporter 0.0043 0.0109 0.4098
Brugia malayi Protein-tyrosine phosphatase containing protein 0.0017 0.0013 0.0016
Echinococcus granulosus nuclear receptor subfamily 4 group A 0.0048 0.0128 0.0206
Brugia malayi Ligand-binding domain of nuclear hormone receptor family protein 0.0102 0.0329 0.1182
Echinococcus multilocularis isocitrate dehydrogenase 0.0018 0.0018 0.0004
Onchocerca volvulus Huntingtin homolog 0.0122 0.0403 0.6418
Echinococcus multilocularis dihydropyrimidine dehydrogenase (NADP+) 0.0036 0.0082 0.0068
Brugia malayi MH2 domain containing protein 0.0018 0.0017 0.0028
Leishmania major isocitrate dehydrogenase [NADP], mitochondrial precursor, putative 0.0018 0.0018 0.0067
Plasmodium vivax amine transporter, putative 0.0043 0.0109 0.0597
Echinococcus multilocularis serotonin transporter 0.0043 0.0109 0.0096
Plasmodium falciparum geranylgeranyl transferase type-2 subunit alpha, putative 0.0134 0.045 0.283
Brugia malayi Protein-tyrosine phosphatase containing protein 0.0017 0.0013 0.0016
Brugia malayi Nuclear hormone receptor family member nhr-25 0.0102 0.0329 0.1182
Echinococcus granulosus Basic leucine zipper bZIP transcription 0.0036 0.0082 0.0124
Loa Loa (eye worm) protein-tyrosine phosphatase 0.0017 0.0013 0.005
Trichomonas vaginalis protein farnesyltransferase alpha subunit, putative 0.0428 0.1546 1
Brugia malayi Thioredoxin reductase 0.0038 0.0092 0.0307
Loa Loa (eye worm) protein-tyrosine phosphatase 0.0017 0.0013 0.005
Loa Loa (eye worm) protein-tyrosine phosphatase 0.0017 0.0013 0.005
Trypanosoma cruzi lanosterol synthase, putative 0.0097 0.031 0.4573
Mycobacterium tuberculosis Phenolpthiocerol synthesis type-I polyketide synthase PpsC 0.003 0.006 0.0055
Brugia malayi AMP-binding enzyme family protein 0.0026 0.0045 0.0132
Entamoeba histolytica dihydropyrimidine dehydrogenase, putative 0.0036 0.0082 0.0444
Loa Loa (eye worm) hypothetical protein 0.0043 0.0109 0.0401
Schistosoma mansoni chromobox protein 0.0081 0.0253 0.0437
Leishmania major aldehyde dehydrogenase, mitochondrial precursor 0.0065 0.0191 0.2747
Loa Loa (eye worm) hypothetical protein 0.0338 0.121 0.4456
Giardia lamblia GTP-binding nuclear protein RAN/TC4 0.0023 0.0034 0.0132
Trypanosoma brucei GTP-binding nuclear protein rtb2, putative 0.0023 0.0034 0.0312
Brugia malayi Protein-tyrosine phosphatase containing protein 0.0017 0.0013 0.0016
Mycobacterium leprae Probable polyketide synthase Pks1 0.0032 0.0067 0.1326
Brugia malayi Heterochromatin protein 1 0.0081 0.0253 0.0899
Loa Loa (eye worm) MBCTL1 0.0057 0.0161 0.0592
Mycobacterium ulcerans thioesterase 0.0025 0.0041 0.0326
Schistosoma mansoni coup transcription factor 0.0102 0.0329 0.0574
Echinococcus granulosus nuclear receptor 2DBD gamma 0.0102 0.0329 0.0567
Loa Loa (eye worm) hypothetical protein 0.0093 0.0296 0.1091
Entamoeba histolytica nicotinate phosphoribosyltransferase, putative 0.007 0.0209 0.1278
Leishmania major nicotinate phosphoribosyltransferase, putative 0.007 0.0209 0.3025
Toxoplasma gondii thioredoxin reductase 0.0038 0.0092 0.0805
Echinococcus multilocularis thioredoxin glutathione reductase 0.0039 0.0094 0.0081
Loa Loa (eye worm) hypothetical protein 0.0016 0.0009 0.0033
Entamoeba histolytica Rab geranylgeranyltransferase alpha subunit, putative 0.0134 0.045 0.2851
Brugia malayi Nuclear hormone receptor-like 1 0.0054 0.015 0.052
Echinococcus multilocularis lamin dm0 0.0093 0.0296 0.0283
Schistosoma mansoni thyroid hormone receptor 0.0102 0.0329 0.0574
Trypanosoma brucei nicotinate phosphoribosyltransferase, putative 0.007 0.0209 0.3025
Echinococcus multilocularis sodium dependent neurotransmitter transporter 0.0043 0.0109 0.0096
Brugia malayi photoreceptor-specific nuclear receptor 0.0102 0.0329 0.1182
Onchocerca volvulus 0.0026 0.0045 0.0583
Schistosoma mansoni nuclear receptor 0.0048 0.0128 0.0214
Leishmania major 4-coumarate:coa ligase-like protein 0.0026 0.0045 0.0485
Schistosoma mansoni nuclear receptor 2DBD-gamma 0.0102 0.0329 0.0574
Mycobacterium ulcerans thioesterase TesA 0.0025 0.0041 0.0326
Brugia malayi Nuclear hormone receptor family member nhr-1 0.0102 0.0329 0.1182
Schistosoma mansoni nicotinate phosphoribosyltransferase related pre-B cell enhancing factor 0.0377 0.1353 0.241
Loa Loa (eye worm) hypothetical protein 0.0017 0.0011 0.0041
Echinococcus granulosus polycomb protein SCMH1 0.005 0.0135 0.0218
Chlamydia trachomatis cytosol aminopeptidase 0.0032 0.0068 0.5397
Schistosoma mansoni non-receptor protein-tyrosine phosphatase 0.0017 0.0013 0.0008
Loa Loa (eye worm) glutathione reductase 0.0038 0.0092 0.034
Echinococcus granulosus chromobox protein 1 0.0081 0.0253 0.0429
Echinococcus granulosus protein farnesyltransferase subunit beta 0.0098 0.0313 0.0537
Echinococcus multilocularis biogenic amine (5HT) receptor 0.0075 0.023 0.0217
Onchocerca volvulus 0.0017 0.0013 0.0071
Echinococcus multilocularis guanine nucleotide binding protein G(s) subunit 0.005 0.0134 0.0121
Echinococcus multilocularis nuclear receptor 2DBD gamma 0.0102 0.0329 0.0316
Schistosoma mansoni pcd6 interacting protein-related 0.0017 0.0013 0.0008
Trypanosoma cruzi hypothetical protein, conserved 0.0134 0.045 0.6744
Loa Loa (eye worm) hypothetical protein 0.0026 0.0048 0.0175
Schistosoma mansoni NADP-specific isocitrate dehydrogenase 0.0018 0.0018 0.0016
Schistosoma mansoni receptor tyrosine phosphatase type r2a 0.0017 0.0013 0.0008
Schistosoma mansoni Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) 0.005 0.0134 0.0224
Mycobacterium tuberculosis Probable multifunctional mycocerosic acid synthase membrane-associated Mas 0.0032 0.0067 0.0063
Mycobacterium leprae PROBABLE FATTY-ACID-CoA LIGASE FADD7 (FATTY-ACID-CoA SYNTHETASE) (FATTY-ACID-CoA SYNTHASE) 0.0026 0.0045 0.067
Echinococcus multilocularis Tolloid protein 1 0.0056 0.0156 0.0143
Echinococcus multilocularis protein patched 0.0079 0.0242 0.0229
Schistosoma mansoni subfamily M12A unassigned peptidase (M12 family) 0.0056 0.0156 0.0264
Onchocerca volvulus 0.0059 0.017 0.2627
Mycobacterium ulcerans phenolpthiocerol synthesis type-I polyketide synthase PpsD 0.003 0.006 0.0615
Echinococcus multilocularis serotonin receptor 0.0032 0.0067 0.0054
Brugia malayi Bloom's syndrome protein homolog 0.0024 0.0037 0.0104
Loa Loa (eye worm) bone morphogenetic protein 1b 0.0056 0.0156 0.0575
Trypanosoma brucei beta lactamase 0.002 0.0023 0.0148
Mycobacterium leprae Probable cytosol aminopeptidase PepB 0.0032 0.0068 0.137
Brugia malayi GTP-binding nuclear protein RAN/TC4 0.0023 0.0034 0.0091
Toxoplasma gondii type I fatty acid synthase, putative 0.0021 0.0028 0.0184
Schistosoma mansoni geranylgeranyl transferase type I beta subunit 0.0026 0.0048 0.0069
Plasmodium vivax prenyltransferase alpha subunit, putative 0.0428 0.1546 1
Schistosoma mansoni receptor protein tyrosine phosphatase r (pcptp1) 0.0017 0.0013 0.0008
Brugia malayi Protein-tyrosine phosphatase containing protein 0.0017 0.0013 0.0016
Trichomonas vaginalis dihydroorotate dehydrogenase, putative 0.0036 0.0082 0.0444
Wolbachia endosymbiont of Brugia malayi dihydroorotate dehydrogenase 2 0.0082 0.0255 0.5878
Loa Loa (eye worm) hypothetical protein 0.0048 0.0128 0.0472
Chlamydia trachomatis Ssodium-dependent amino acid transporter 0.0043 0.0109 1
Loa Loa (eye worm) hypothetical protein 0.0102 0.0329 0.1212
Brugia malayi glutathione reductase 0.0038 0.0092 0.0307
Schistosoma mansoni nuclear hormone receptor nor-1/nor-2 0.0102 0.0329 0.0574
Loa Loa (eye worm) hypothetical protein 0.0022 0.0032 0.0119
Echinococcus multilocularis importin subunit beta 1 0.0031 0.0064 0.0051
Wolbachia endosymbiont of Brugia malayi fructose-1,6-bisphosphatase 0.0123 0.0406 1
Mycobacterium ulcerans long-chain-fatty-acid--CoA ligase 0.0026 0.0045 0.0378
Loa Loa (eye worm) hypothetical protein 0.0017 0.0013 0.005
Echinococcus multilocularis guanine nucleotide binding protein G(s) subunit 0.005 0.0134 0.0121
Plasmodium falciparum nicotinate phosphoribosyltransferase, putative 0.007 0.0209 0.1254
Mycobacterium tuberculosis Probable thioesterase TesA 0.0025 0.0041 0.0034
Brugia malayi mbt repeat family protein 0.005 0.0135 0.0465
Schistosoma mansoni protein tyrosine phosphatase n11 (shp2) 0.0017 0.0013 0.0008
Brugia malayi Integrin beta pat-3 precursor 0.0147 0.0497 0.1803
Brugia malayi Nuclear hormone receptor family member nhr-31 0.0102 0.0329 0.1182
Brugia malayi MH1 domain containing protein 0.0018 0.0017 0.0028
Toxoplasma gondii Sodium:neurotransmitter symporter family protein 0.0043 0.0109 0.0966
Schistosoma mansoni hypothetical protein 0.0338 0.121 0.2155
Trypanosoma brucei hypothetical protein, conserved 0.0134 0.045 0.6744
Brugia malayi hypothetical protein 0.0017 0.0013 0.0016
Echinococcus multilocularis protein farnesyltransferase subunit beta 0.0098 0.0313 0.03
Trypanosoma cruzi hypothetical protein, conserved 0.0134 0.045 0.6744
Plasmodium vivax holo-[acyl-carrier-protein] synthase, putative 0.0024 0.0039 0.0141
Trypanosoma cruzi myo-inositol-1(or 4)-monophosphatase 1, putative 0.0123 0.0406 0.6057
Mycobacterium ulcerans multifunctional mycocerosic acid synthase membrane-associated Mas 0.0032 0.0067 0.0722
Mycobacterium ulcerans phosphopantetheinyl transferase, PptII 0.0024 0.0039 0.0293
Mycobacterium tuberculosis Probable dehydrogenase 0.0088 0.0276 0.0301
Loa Loa (eye worm) hypothetical protein 0.0017 0.0013 0.005
Loa Loa (eye worm) hypothetical protein 0.0048 0.0128 0.0472
Giardia lamblia DNA repair protein RAD52 0.0361 0.1294 0.8356
Loa Loa (eye worm) Sodium:neurotransmitter symporter family protein 0.0221 0.0772 0.2841
Echinococcus granulosus inositol monophosphatase 1 0.0123 0.0406 0.0704
Brugia malayi Nuclear hormone receptor-like 1 0.0054 0.015 0.052
Loa Loa (eye worm) latrophilin receptor protein 2 0.0157 0.0533 0.1962
Mycobacterium leprae PHENOLPTHIOCEROL SYNTHESIS TYPE-I POLYKETIDE SYNTHASE PPSA 0.003 0.006 0.1121
Brugia malayi Prenyltransferase and squalene oxidase repeat family protein 0.0026 0.0048 0.0142
Onchocerca volvulus Nuclear receptor subfamily 6 group A member 1 homolog 0.0048 0.0128 0.1942
Echinococcus granulosus Protein patched homolog 1 0.0079 0.0242 0.0411
Loa Loa (eye worm) hypothetical protein 0.0221 0.0772 0.2841
Toxoplasma gondii isocitrate dehydrogenase 0.0018 0.0018 0.0085
Mycobacterium tuberculosis Halimadienyl diphosphate synthase 0.0097 0.031 0.034
Toxoplasma gondii hypothetical protein 0.0043 0.0109 0.0966
Loa Loa (eye worm) hypothetical protein 0.0048 0.0128 0.0472
Schistosoma mansoni hypothetical protein 0.0157 0.0533 0.0939
Mycobacterium leprae Probable dihydroorotate dehydrogenase PyrD 0.0082 0.0255 0.6926
Loa Loa (eye worm) hypothetical protein 0.0017 0.0013 0.005
Trichomonas vaginalis type I geranylgeranyltransferase beta subunit, putative 0.0098 0.0313 0.1953
Brugia malayi Dihydroorotate dehydrogenase, mitochondrial precursor, putative 0.0082 0.0255 0.0907
Trypanosoma cruzi dihydroorotate dehydrogenase (fumarate), putative 0.0082 0.0255 0.3725
Trypanosoma brucei metallo-peptidase, Clan MF, Family M17 0.0019 0.002 0.0097
Mycobacterium ulcerans acyl-CoA synthetase 0.0026 0.0045 0.0378
Schistosoma mansoni retinoid-x-receptor (RXR) 0.0054 0.015 0.0252
Echinococcus granulosus Tolloid protein 1 0.0056 0.0156 0.0256
Mycobacterium ulcerans dihydroorotate dehydrogenase 2 0.0082 0.0255 0.3655
Trichomonas vaginalis ap endonuclease, putative 0.0058 0.0167 0.0999
Onchocerca volvulus 4.1 G protein, putative homolog 0.0017 0.0013 0.0071
Loa Loa (eye worm) hypothetical protein 0.0017 0.0013 0.005
Schistosoma mansoni sodium/chloride dependent transporter 0.0043 0.0109 0.0179
Loa Loa (eye worm) kelch domain-containing protein family protein 0.0027 0.005 0.0183
Trypanosoma cruzi isocitrate dehydrogenase [NADP], mitochondrial precursor, putative 0.0018 0.0018 0.0067
Schistosoma mansoni protein tyrosine phosphatase 0.0017 0.0013 0.0008
Trichomonas vaginalis DNA helicase recq1, putative 0.0024 0.0037 0.0156
Mycobacterium tuberculosis Polyketide synthase Pks13 0.0045 0.0115 0.0117
Loa Loa (eye worm) multiple epidermal growth factor-like domains 6 0.0018 0.0016 0.0058
Loa Loa (eye worm) hypothetical protein 0.0019 0.0021 0.0076
Mycobacterium tuberculosis NAD(P)H quinone reductase LpdA 0.0097 0.0312 0.0343
Brugia malayi Nuclear hormone receptor E75 0.0048 0.0128 0.044
Echinococcus multilocularis n acetylated alpha linked acidic dipeptidase 2 0.0069 0.0205 0.0192
Trypanosoma cruzi trypanothione reductase, putative 0.0038 0.0092 0.1217
Echinococcus granulosus guanine nucleotide binding protein Gs subunit 0.005 0.0134 0.0216
Loa Loa (eye worm) hypothetical protein 0.0048 0.0128 0.0472
Brugia malayi nuclear receptor RXR 0.0054 0.015 0.052
Loa Loa (eye worm) nuclear hormone receptor family member nhr-1 0.0102 0.0329 0.1212
Loa Loa (eye worm) mbt repeat family protein 0.005 0.0135 0.0497
Mycobacterium tuberculosis Dihydrolipoamide dehydrogenase LpdC (lipoamide reductase (NADH)) (lipoyl dehydrogenase) (dihydrolipoyl dehydrogenase) (diaphoras 0.0097 0.0312 0.0343
Echinococcus multilocularis sterol regulatory element binding protein 0.0079 0.0242 0.0229
Trichomonas vaginalis DNA helicase recq, putative 0.0024 0.0037 0.0156
Brugia malayi Nuclear hormone receptor family member nhr-41 0.0102 0.0329 0.1182
Brugia malayi Nuclear hormone receptor family member nhr-49 0.0102 0.0329 0.1182
Onchocerca volvulus 0.0017 0.0013 0.0071
Loa Loa (eye worm) hypothetical protein 0.0048 0.0128 0.0472
Echinococcus multilocularis lamin 0.0093 0.0296 0.0283
Loa Loa (eye worm) hypothetical protein 0.0017 0.0013 0.005
Loa Loa (eye worm) hypothetical protein 0.005 0.0135 0.0497
Toxoplasma gondii ATP-dependent DNA helicase, RecQ family protein 0.0024 0.0037 0.0274
Trypanosoma brucei ATP-dependent DEAD/H DNA helicase recQ, putative 0.0024 0.0037 0.0369
Echinococcus granulosus arachidonate 5 lipoxygenase 0.0037 0.0086 0.013
Loa Loa (eye worm) nuclear hormone receptor-like 1 0.0054 0.015 0.0551
Loa Loa (eye worm) DR-78 0.0048 0.0128 0.0472
Schistosoma mansoni protein farnesyltransferase subunit beta 0.0098 0.0313 0.0545
Brugia malayi hypothetical protein 0.0048 0.0128 0.044
Loa Loa (eye worm) hypothetical protein 0.0017 0.0013 0.005
Toxoplasma gondii calcium binding egf domain-containing protein 0.0018 0.0016 0.0066
Brugia malayi nuclear hormone receptor family member nhr-6 0.0048 0.0128 0.044
Brugia malayi hypothetical protein 0.0017 0.0013 0.0016
Schistosoma mansoni receptor protein tyrosine phosphatase n (ia2) 0.0017 0.0013 0.0008
Brugia malayi AMP-binding enzyme family protein 0.0026 0.0045 0.0132
Echinococcus granulosus serotonin transporter 0.0043 0.0109 0.0172
Brugia malayi hypothetical protein 0.0022 0.0032 0.0086
Brugia malayi MH1 domain containing protein 0.0018 0.0017 0.0028
Echinococcus granulosus retinoic acid receptor rxr beta a 0.0102 0.0329 0.0567
Trypanosoma cruzi mitogen-activated protein kinase 3, putative 0.0043 0.0108 0.1459
Echinococcus granulosus protein farnesyltransferase alpha subunit 0.0428 0.1546 0.2751
Leishmania major cytosolic leucyl aminopeptidase,metallo-peptidase, Clan MF, Family M17 0.0019 0.002 0.0097
Brugia malayi Steroid receptor seven-up type 2 0.0102 0.0329 0.1182
Toxoplasma gondii exonuclease III APE 0.0058 0.0167 0.1522
Schistosoma mansoni hepatocyte nuclear factor 4-alpha (hnf-4-alpha) 0.0048 0.0128 0.0214
Loa Loa (eye worm) hypothetical protein 0.0102 0.0329 0.1212
Trichomonas vaginalis chromobox protein, putative 0.0049 0.0132 0.0774
Entamoeba histolytica protein farnesyltransferase beta subunit, putative 0.0098 0.0313 0.1953
Mycobacterium tuberculosis Probable polyketide synthase Pks5 0.0029 0.0057 0.0051
Onchocerca volvulus 0.0036 0.0082 0.1194
Brugia malayi Nuclear hormone receptor family member nhr-14 0.0102 0.0329 0.1182
Mycobacterium tuberculosis Probable oxidoreductase 0.0097 0.0312 0.0343
Mycobacterium tuberculosis Nicotinic acid phosphoribosyltransferase PncB1 0.007 0.0209 0.0225
Schistosoma mansoni survival motor neuron protein 0.0151 0.0513 0.0904
Entamoeba histolytica hypothetical protein 0.0025 0.0042 0.0188
Trypanosoma brucei lanosterol synthase 0.0097 0.031 0.4573
Trypanosoma brucei 3-hydroxy-3-methylglutaryl-CoA reductase, putative 0.0191 0.0661 1
Loa Loa (eye worm) hypothetical protein 0.0048 0.0128 0.0472
Loa Loa (eye worm) hypothetical protein 0.0122 0.0403 0.1484
Brugia malayi hypothetical protein 0.0054 0.015 0.052
Mycobacterium leprae Probable multifunctional mycocerosic acid synthase membrane associated enzyme Mas 0.0032 0.0067 0.1326
Brugia malayi oxidoreductase, zinc-binding dehydrogenase family protein 0.0056 0.0159 0.0555
Mycobacterium ulcerans fatty-acid-CoA ligase 0.0026 0.0045 0.0378
Loa Loa (eye worm) protein-tyrosine phosphatase 1 0.0017 0.0013 0.005
Echinococcus granulosus biogenic amine 5HT receptor 0.0032 0.0067 0.0097
Loa Loa (eye worm) hypothetical protein 0.0024 0.0037 0.0137
Echinococcus granulosus ATP dependent DNA helicase Q1 0.0024 0.0037 0.0043
Trichomonas vaginalis conserved hypothetical protein 0.0046 0.0119 0.069
Brugia malayi Nuclear hormone receptor E75 0.0048 0.0128 0.044
Echinococcus multilocularis ecdysone induced protein 78C 0.0102 0.0329 0.0316
Schistosoma mansoni nuclear hormone receptor 0.0102 0.0329 0.0574
Onchocerca volvulus 0.0134 0.045 0.7188
Onchocerca volvulus 0.0043 0.0109 0.1629
Schistosoma mansoni sex comb on midleg homolog 0.005 0.0135 0.0226
Trichomonas vaginalis protein farnesyltransferase alpha subunit/RAB geranylgeranyl transferase alpha subunit, putative 0.0428 0.1546 1
Loa Loa (eye worm) hypothetical protein 0.0045 0.0117 0.0429
Echinococcus granulosus nuclear receptor nhr 48 0.0048 0.0128 0.0206
Plasmodium falciparum M17 leucyl aminopeptidase 0.0019 0.002 0.0013
Wolbachia endosymbiont of Brugia malayi exonuclease III 0.0058 0.0167 0.3471
Echinococcus multilocularis DNA (apurinic or apyrimidinic site) lyase 0.0058 0.0167 0.0153
Trypanosoma brucei trypanothione reductase 0.0038 0.0092 0.1217
Loa Loa (eye worm) hypothetical protein 0.0017 0.0013 0.005
Loa Loa (eye worm) hypothetical protein 0.0017 0.0013 0.005
Echinococcus granulosus Niemann Pick C1 protein 0.0079 0.0242 0.0411
Echinococcus granulosus laminin 0.0018 0.0016 0.0004
Echinococcus granulosus importin subunit beta 1 0.0031 0.0064 0.0091
Echinococcus granulosus FTZ F1 alpha 0.0102 0.0329 0.0567
Echinococcus granulosus FTZ F1 nuclear receptor protein 0.0102 0.0329 0.0567
Onchocerca volvulus 0.0102 0.0329 0.5214
Plasmodium falciparum thioredoxin reductase 0.0038 0.0092 0.0488
Schistosoma mansoni sodium/chloride dependent neurotransmitter transporter 0.0043 0.0109 0.0179
Plasmodium vivax geranylgeranyl transferase type2 beta subunit, putative 0.0026 0.0048 0.0195
Brugia malayi Zinc finger, C2H2 type family protein 0.0032 0.0068 0.0219
Schistosoma mansoni ecdysone-induced protein 78c (dr-78) 0.0054 0.015 0.0252
Echinococcus multilocularis NADP dependent isocitrate dehydrogenase 0.0018 0.0018 0.0004
Onchocerca volvulus 0.0017 0.0013 0.0071
Echinococcus multilocularis NADP dependent isocitrate dehydrogenase 0.0018 0.0018 0.0004
Echinococcus granulosus nuclear receptor 2DBD gamma 0.0102 0.0329 0.0567
Loa Loa (eye worm) inositol-1 0.0123 0.0406 0.1494
Onchocerca volvulus Fatty acid synthase homolog 0.0054 0.0149 0.2281
Brugia malayi P38 map kinase family protein 2 0.0043 0.0108 0.0365
Echinococcus multilocularis inositol monophosphatase 1 0.0123 0.0406 0.0393
Onchocerca volvulus 0.0017 0.0013 0.0071
Loa Loa (eye worm) transcription factor SMAD2 0.0267 0.0943 0.3473
Loa Loa (eye worm) hypothetical protein 0.0102 0.0329 0.1212
Brugia malayi Ligand-binding domain of nuclear hormone receptor family protein 0.0102 0.0329 0.1182
Plasmodium vivax glutathione reductase, putative 0.0038 0.0092 0.0488
Loa Loa (eye worm) hypothetical protein 0.0036 0.0082 0.0303
Echinococcus multilocularis FTZ F1 nuclear receptor protein 0.0102 0.0329 0.0316
Brugia malayi Prenyltransferase and squalene oxidase repeat family protein 0.0098 0.0313 0.1122
Loa Loa (eye worm) hypothetical protein 0.0048 0.0128 0.0472
Toxoplasma gondii inositol(myo)-1(or 4)-monophosphatase 2, putative 0.0123 0.0406 0.3832
Trichomonas vaginalis dihydroorotate dehydrogenase, putative 0.0032 0.0068 0.0358
Leishmania major 4-coumarate:coa ligase-like protein 0.0026 0.0045 0.0485
Schistosoma mansoni lamin 0.0093 0.0296 0.0515
Echinococcus multilocularis geranylgeranyl transferase type 2 subunit alpha 0.0134 0.045 0.0437
Leishmania major mitogen-activated protein kinase 3, putative,map kinase 3, putative 0.0043 0.0108 0.1459
Trichomonas vaginalis myo inositol monophosphatase, putative 0.0123 0.0406 0.256
Echinococcus multilocularis musashi 0.0093 0.0296 0.0283
Mycobacterium ulcerans phenolpthiocerol synthesis type-I polyketide synthase PpsB 0.0024 0.0038 0.0276
Plasmodium falciparum holo-[acyl-carrier-protein] synthase, putative 0.0024 0.0039 0.0141
Loa Loa (eye worm) MH1 domain-containing protein 0.0018 0.0017 0.0061
Loa Loa (eye worm) Smad1 0.0018 0.0017 0.0061
Brugia malayi isocitrate dehydrogenase 0.0018 0.0018 0.0032
Onchocerca volvulus 0.0086 0.0271 0.426
Loa Loa (eye worm) prenyltransferase alpha subunit repeat containing protein 0.0134 0.045 0.1658
Echinococcus multilocularis leucine aminopeptidase protein 0.0032 0.0068 0.0055
Echinococcus multilocularis FTZ F1 alpha 0.0102 0.0329 0.0316
Echinococcus granulosus sterol regulatory element binding protein 0.0079 0.0242 0.0411
Loa Loa (eye worm) hypothetical protein 0.0032 0.0067 0.0248
Mycobacterium ulcerans aldehyde dehydrogenase 0.0065 0.0191 0.2666
Schistosoma mansoni zinc finger protein 0.0048 0.0128 0.0214
Echinococcus multilocularis Basic leucine zipper (bZIP) transcription 0.0036 0.0082 0.0069
Schistosoma mansoni norepinephrine/norepinephrine transporter 0.0043 0.0109 0.0179
Onchocerca volvulus 0.0017 0.0013 0.0071
Echinococcus granulosus cytoplasmic intermediate filament protein 0.0045 0.0117 0.0185
Plasmodium falciparum dihydroorotate dehydrogenase 0.0082 0.0255 0.1551
Trichomonas vaginalis inositol monophosphatase, putative 0.0123 0.0406 0.256
Loa Loa (eye worm) protein-tyrosine phosphatase 0.0017 0.0013 0.005
Brugia malayi Protein-tyrosine phosphatase containing protein 0.0017 0.0013 0.0016
Echinococcus multilocularis nuclear receptor 2DBD gamma 0.0048 0.0128 0.0115
Brugia malayi Beta-ketoacyl synthase, N-terminal domain containing protein 0.003 0.006 0.0188
Trypanosoma brucei isocitrate dehydrogenase [NADP], mitochondrial precursor, putative 0.0018 0.0018 0.0067
Trichomonas vaginalis 3-hydroxy-3-methylglutaryl-coenzyme A reductase, putative 0.009 0.0283 0.176
Loa Loa (eye worm) hypothetical protein 0.0019 0.0021 0.0076
Echinococcus granulosus snurportin 1 0.033 0.1178 0.209
Trypanosoma cruzi hypothetical protein, conserved 0.0026 0.0048 0.0528
Schistosoma mansoni nicotinate phosphoribosyltransferase 0.007 0.0209 0.0359
Brugia malayi Sodium:neurotransmitter symporter family protein 1, putative 0.0043 0.0109 0.0369
Echinococcus granulosus GPCR family 2 0.0157 0.0533 0.0932
Mycobacterium tuberculosis Polyketide synthase Pks12 0.0032 0.0067 0.0063
Schistosoma mansoni aldehyde dehydrogenase 0.0065 0.0191 0.0327
Onchocerca volvulus Bile acid receptor homolog 0.0102 0.0329 0.5214
Loa Loa (eye worm) hypothetical protein 0.0079 0.0242 0.0892
Entamoeba histolytica recQ family helicase, putative 0.0024 0.0037 0.0156
Loa Loa (eye worm) hypothetical protein 0.0054 0.015 0.0551
Entamoeba histolytica hypothetical protein 0.0036 0.0082 0.0449
Toxoplasma gondii calcium binding egf domain-containing protein 0.0018 0.0016 0.0066
Echinococcus granulosus tm gpcr rhodopsin 0.0153 0.0519 0.0907
Brugia malayi Iron-sulfur cluster assembly accessory protein 0.0151 0.0513 0.1863
Onchocerca volvulus 0.0017 0.0013 0.0071
Brugia malayi mbt repeat family protein 0.005 0.0135 0.0465
Echinococcus granulosus uncharacterized sodium dependent transporter 0.0043 0.0109 0.0172
Brugia malayi Sodium:neurotransmitter symporter family protein 0.0043 0.0109 0.0369
Loa Loa (eye worm) hypothetical protein 0.0048 0.0128 0.0472
Schistosoma mansoni hypothetical protein 0.0023 0.0034 0.0045
Echinococcus multilocularis cytoplasmic intermediate filament protein 0.0045 0.0117 0.0103
Echinococcus multilocularis Nuclear hormone receptor HR96 0.0048 0.0128 0.0115
Loa Loa (eye worm) hypothetical protein 0.0017 0.0013 0.005
Onchocerca volvulus 0.0043 0.0109 0.1629
Trypanosoma cruzi importin beta-1 subunit, putative 0.0025 0.0042 0.0445
Mycobacterium tuberculosis Probable NADH dehydrogenase Ndh 0.0088 0.0276 0.0301
Loa Loa (eye worm) AStacin protease 0.0035 0.0079 0.0289
Echinococcus multilocularis nicotinamide phosphoribosyltransferase 0.0377 0.1353 0.1341
Loa Loa (eye worm) hypothetical protein 0.0102 0.0329 0.1212
Echinococcus multilocularis microtubule associated protein 2 0.1512 0.5584 0.5578
Loa Loa (eye worm) hypothetical protein 0.0017 0.0013 0.005
Schistosoma mansoni sodium/chloride dependent transporter 0.0221 0.0772 0.1368
Loa Loa (eye worm) hypothetical protein 0.0019 0.0021 0.0076
Trichomonas vaginalis 3-hydroxy-3-methylglutaryl-coenzyme A reductase, putative 0.009 0.0283 0.176
Loa Loa (eye worm) hypothetical protein 0.0017 0.0013 0.005
Brugia malayi MH2 domain containing protein 0.0267 0.0943 0.3451
Mycobacterium leprae PROBABLE NADH DEHYDROGENASE NDH 0.0088 0.0276 0.7558
Entamoeba histolytica DNA repair and recombination protein RAD52, putative 0.0361 0.1294 0.8356
Trichomonas vaginalis geranylgeranyl transferase type II beta subunit, putative 0.0098 0.0313 0.1953
Echinococcus multilocularis chromobox protein 1 0.0081 0.0253 0.0239
Trypanosoma cruzi 3-hydroxy-3-methylglutaryl-CoA reductase 0.0191 0.0661 1
Loa Loa (eye worm) GTP-binding nuclear protein RAN/TC4 0.0023 0.0034 0.0124
Echinococcus multilocularis survival motor neuron protein 1 0.0742 0.2716 0.2706
Mycobacterium tuberculosis Possible penicillin-binding protein 0.0072 0.0216 0.0233
Echinococcus granulosus SAM and MBT domain containing protein 0.005 0.0135 0.0218
Entamoeba histolytica Rad52/22 family double-strand break repair protein, putative 0.0103 0.0332 0.2076
Brugia malayi nuclear hormone receptor family member odr-7 0.0048 0.0128 0.044
Entamoeba histolytica acyl-CoA synthetase, putative 0.0026 0.0045 0.0205
Entamoeba histolytica hypothetical protein 0.0036 0.0082 0.0449
Mycobacterium ulcerans polyketide synthase Pks13 0.0045 0.0115 0.1472
Mycobacterium tuberculosis Probable polyketide synthase Pks8 0.0024 0.004 0.0032
Loa Loa (eye worm) low-density lipoprotein receptor repeat class B containing protein 0.0016 0.0009 0.0033
Loa Loa (eye worm) ATP-dependent DNA helicase 0.0024 0.0037 0.0137
Loa Loa (eye worm) hypothetical protein 0.0048 0.0128 0.0472
Mycobacterium tuberculosis Nicotinic acid phosphoribosyltransferase PncB2 0.007 0.0209 0.0225
Echinococcus multilocularis nuclear receptor subfamily 4 group A 0.0048 0.0128 0.0115
Loa Loa (eye worm) hypothetical protein 0.0054 0.015 0.0551
Echinococcus granulosus nuclear receptor 2DBD gamma 0.0048 0.0128 0.0206
Brugia malayi nuclear hormone receptor 0.0048 0.0128 0.044
Echinococcus multilocularis Smad4 0.0018 0.0017 0.0003
Echinococcus granulosus histone acetyltransferase MYST2 0.0057 0.0161 0.0264
Brugia malayi nuclear hormone receptor 0.0102 0.0329 0.1182
Loa Loa (eye worm) integrin beta-2 0.0147 0.0497 0.1831
Echinococcus granulosus geranylgeranyl transferase type I beta subunit 0.0026 0.0048 0.0061
Loa Loa (eye worm) hypothetical protein 0.0017 0.0013 0.005
Brugia malayi nuclear receptor NHR-88 0.0102 0.0329 0.1182
Loa Loa (eye worm) hypothetical protein 0.0102 0.0329 0.1212
Brugia malayi AMP-binding enzyme family protein 0.0035 0.0081 0.0265
Loa Loa (eye worm) hypothetical protein 0.0017 0.0013 0.005
Brugia malayi Isocitrate dehydrogenase 0.0018 0.0018 0.0032
Schistosoma mansoni geranylgeranyl transferase type II beta subunit 0.0026 0.0048 0.0069
Mycobacterium tuberculosis Phenolpthiocerol synthesis type-I polyketide synthase PpsA 0.003 0.006 0.0055
Mycobacterium ulcerans polyketide synthase Pks9 0.002 0.0022 0.0027
Trypanosoma brucei dihydroorotate dehydrogenase (fumarate) 0.0082 0.0255 0.3725
Mycobacterium leprae Polyketide synthase Pks13 0.0045 0.0115 0.2757
Echinococcus granulosus hydroxymethylglutaryl coenzyme A reductase 0.0191 0.0661 0.1163
Loa Loa (eye worm) protein-tyrosine phosphatase 0.0017 0.0013 0.005
Loa Loa (eye worm) hypothetical protein 0.0043 0.0109 0.0401
Schistosoma mansoni FTZ-F1 nuclear receptor-like protein 0.0102 0.0329 0.0574
Echinococcus multilocularis L aminoadipate semialdehyde 0.0086 0.0271 0.0257
Schistosoma mansoni geranylgeranyl transferase type I beta subunit 0.0026 0.0048 0.0069
Schistosoma mansoni transcription factor LCR-F1 0.0036 0.0082 0.0131
Schistosoma mansoni hypothetical protein 0.0036 0.0082 0.0131
Mycobacterium leprae PHENOLPTHIOCEROL SYNTHESIS TYPE-I POLYKETIDE SYNTHASE PPSD 0.003 0.006 0.1121
Mycobacterium tuberculosis Probable aldehyde dehydrogenase 0.0065 0.0191 0.0205
Schistosoma mansoni hypothetical protein 0.0765 0.2801 0.5007
Loa Loa (eye worm) protein-tyrosine phosphatase 0.0017 0.0013 0.005
Loa Loa (eye worm) hypothetical protein 0.0017 0.0013 0.005
Echinococcus multilocularis Niemann Pick C1 protein 0.0079 0.0242 0.0229
Onchocerca volvulus 0.0043 0.0109 0.1629
Schistosoma mansoni sodium-dependent neurotransmitter transporter 0.0043 0.0109 0.0179
Schistosoma mansoni smad1 5 8 and 0.0018 0.0017 0.0014
Schistosoma mansoni sodium/chloride dependent neurotransmitter transporter 0.0043 0.0109 0.0179
Leishmania major farnesyltransferase beta subunit 0.0098 0.0313 0.4621
Onchocerca volvulus 0.0151 0.0513 0.8216
Loa Loa (eye worm) RecQ helicase 0.0024 0.0037 0.0137
Loa Loa (eye worm) cytoplasmic intermediate filament protein 0.005 0.0135 0.0497
Schistosoma mansoni Smad4 0.0018 0.0017 0.0014
Onchocerca volvulus 0.0048 0.0128 0.1942
Loa Loa (eye worm) heterochromatin protein 1 0.0081 0.0253 0.093
Plasmodium vivax GTP-binding nuclear protein RAN/TC4, putative 0.0023 0.0034 0.0104
Toxoplasma gondii type I fatty acid synthase, putative 0.0033 0.0071 0.0597
Brugia malayi Inositol-1 0.0123 0.0406 0.1465
Trichomonas vaginalis protein farnesyltransferase alpha subunit, putative 0.0134 0.045 0.2851
Brugia malayi Probable protein farnesyltransferase beta subunit, putative 0.0026 0.0048 0.0142
Trypanosoma cruzi protein farnesyltransferase alpha subunit, putative 0.0134 0.045 0.6744
Brugia malayi Protein-tyrosine phosphatase containing protein 0.0017 0.0013 0.0016
Mycobacterium ulcerans hypothetical protein 0.0026 0.0045 0.0378
Entamoeba histolytica hypothetical protein 0.0036 0.0082 0.0449
Trichomonas vaginalis ap endonuclease, putative 0.0058 0.0167 0.0999
Trichomonas vaginalis DNA helicase recq, putative 0.0024 0.0037 0.0156
Loa Loa (eye worm) hypothetical protein 0.0102 0.0329 0.1212
Schistosoma mansoni sodium/chloride dependent transporter 0.0221 0.0772 0.1369
Brugia malayi Kelch motif family protein 0.0027 0.005 0.0151
Brugia malayi Sodium:neurotransmitter symporter family protein 0.0221 0.0772 0.2817
Loa Loa (eye worm) nuclear hormone receptor family member nhr-49 0.0102 0.0329 0.1212
Schistosoma mansoni lipoxygenase 0.0026 0.0045 0.0064
Plasmodium falciparum acyl-CoA synthetase 0.0019 0.0021 0.0018
Echinococcus multilocularis endonuclease exonuclease phosphatase 0.0208 0.0726 0.0713
Echinococcus granulosus mitogen activated protein kinase 11 0.0043 0.0108 0.017
Entamoeba histolytica acyl-CoA synthetase, putative 0.0029 0.0056 0.0278
Loa Loa (eye worm) hypothetical protein 0.0048 0.0128 0.0472
Loa Loa (eye worm) fatty acid synthase 0.0029 0.0058 0.0215
Brugia malayi Protein-tyrosine phosphatase containing protein 0.0017 0.0013 0.0016
Loa Loa (eye worm) protein-tyrosine phosphatase 0.0017 0.0013 0.005
Trypanosoma cruzi myo-inositol-1(or 4)-monophosphatase 1, putative 0.0123 0.0406 0.6057
Mycobacterium ulcerans long-chain-fatty-acid-CoA ligase 0.0026 0.0045 0.0378
Schistosoma mansoni scm-relatedprotein containing 4 mbt domains (sfmbt) 0.005 0.0135 0.0226
Toxoplasma gondii Sodium:neurotransmitter symporter family protein 0.0043 0.0109 0.0966

Activities

Activity type Activity value Assay description Source Reference
IC50 (binding) = 19 uM Inhibitory effect against Procollagen C-terminal proteinase ChEMBL. 11086718
IC50 (binding) = 19 uM Inhibitory effect against Procollagen C-terminal proteinase ChEMBL. 11086718

Phenotypes

Whole-cell/tissue/organism interactions

We have no records of whole-cell/tissue assays done with this compound What does this mean?

Many chemical entities in TDR Targets come from high-throughput screenings with whole cells or tissue samples, and not all assayed compounds have been tested against a single a single target protein, probably because they get ruled out during screening process. Even if these compounds may have not been of interest in the original screening, they may come as interesting leads for other screening assays. Furthermore, we may be able to propose drug-target associations using chemical similarities and network patterns.

Annotated phenotypes:

We have no manually annotated phenotypes for this drug. What does this mean? / Care to help?
In TDR Targets, information about phenotypes that are caused by drugs, or by genetic manipulation of cells (e.g. gene knockouts or knockdowns) is manually curated from the literature. These descriptions help to describe the potential of the target for drug development. If no information is available for this gene or if the information is incomplete, this may mean that i) the papers containing this information either appeared after the curation effort for this organism was carried out or they were inadvertently missed by curators; or that ii) the curation effort for this organism has not yet started.
 
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External resources for this compound

No external resources registered for this compound

Bibliographic References

1 literature reference was collected for this gene.

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