Detailed information for compound 1420502

Basic information

Technical information
  • TDR Targets ID: 1420502
  • Name: 1-[(3-acetylphenyl)methyl]-N-(4-furan-2-ylphe nyl)piperidine-3-carboxamide
  • MW: 402.486 | Formula: C25H26N2O3
  • H donors: 1 H acceptors: 2 LogP: 3.5 Rotable bonds: 7
    Rule of 5 violations (Lipinski): 1
  • SMILES: O=C(C1CCCN(C1)Cc1cccc(c1)C(=O)C)Nc1ccc(cc1)c1ccco1
  • InChi: 1S/C25H26N2O3/c1-18(28)21-6-2-5-19(15-21)16-27-13-3-7-22(17-27)25(29)26-23-11-9-20(10-12-23)24-8-4-14-30-24/h2,4-6,8-12,14-15,22H,3,7,13,16-17H2,1H3,(H,26,29)
  • InChiKey: SXXQKDCXEMIHHA-UHFFFAOYSA-N  


Substructure search Similarity search

Network

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Synonyms

  • 1-[(3-acetylphenyl)methyl]-N-[4-(2-furyl)phenyl]piperidine-3-carboxamide
  • 1-[(3-acetylphenyl)methyl]-N-[4-(2-furyl)phenyl]-3-piperidinecarboxamide
  • 1-(3-acetylbenzyl)-N-[4-(2-furyl)phenyl]nipecotamide
  • 1-[(3-ethanoylphenyl)methyl]-N-(4-furan-2-ylphenyl)piperidine-3-carboxamide

Targets

Known targets for this compound

Species Target name Source Bibliographic reference
Homo sapiens euchromatic histone-lysine N-methyltransferase 2 Starlite/ChEMBL No references
Homo sapiens polymerase (DNA directed), eta Starlite/ChEMBL No references
Homo sapiens lysine (K)-specific methyltransferase 2A Starlite/ChEMBL No references
Homo sapiens ATPase family, AAA domain containing 5 Starlite/ChEMBL No references
Homo sapiens chromobox homolog 1 Starlite/ChEMBL No references
Equus caballus Ferritin light chain Starlite/ChEMBL No references
Homo sapiens geminin, DNA replication inhibitor Starlite/ChEMBL No references
Homo sapiens nuclear factor, erythroid 2-like 2 Starlite/ChEMBL No references

Predicted pathogen targets for this compound

By orthology
Species Potential target Known druggable target/s Ortholog Group
Echinococcus granulosus chromobox protein 1 Get druggable targets OG5_129545 All targets in OG5_129545
Schistosoma japonicum ko:K03509 DNA polymerase eta subunit, putative Get druggable targets OG5_128521 All targets in OG5_128521
Leishmania braziliensis DNA polymerase eta, putative Get druggable targets OG5_128521 All targets in OG5_128521
Schistosoma japonicum ko:K03509 DNA polymerase eta subunit, putative Get druggable targets OG5_128521 All targets in OG5_128521
Schistosoma mansoni chromobox protein Get druggable targets OG5_129545 All targets in OG5_129545
Schistosoma mansoni chromobox protein Get druggable targets OG5_129545 All targets in OG5_129545
Onchocerca volvulus Heterochromatin protein 1 homolog Get druggable targets OG5_129545 All targets in OG5_129545
Cryptosporidium parvum DinB/family X-type DNA polymerase Get druggable targets OG5_128521 All targets in OG5_128521
Schistosoma mansoni DNA polymerase eta Get druggable targets OG5_128521 All targets in OG5_128521
Toxoplasma gondii histone lysine methyltransferase SET1 Get druggable targets OG5_130642 All targets in OG5_130642
Trypanosoma brucei gambiense DNA polymerase eta, putative Get druggable targets OG5_128521 All targets in OG5_128521
Onchocerca volvulus Get druggable targets OG5_129545 All targets in OG5_129545
Trypanosoma cruzi DNA polymerase eta, putative Get druggable targets OG5_128521 All targets in OG5_128521
Leishmania major DNA polymerase eta, putative Get druggable targets OG5_128521 All targets in OG5_128521
Trichomonas vaginalis chromobox protein, putative Get druggable targets OG5_129545 All targets in OG5_129545
Leishmania infantum DNA polymerase eta, putative Get druggable targets OG5_128521 All targets in OG5_128521
Trichomonas vaginalis set domain proteins, putative Get druggable targets OG5_131470 All targets in OG5_131470
Loa Loa (eye worm) hypothetical protein Get druggable targets OG5_129545 All targets in OG5_129545
Trichomonas vaginalis chromobox protein, putative Get druggable targets OG5_129545 All targets in OG5_129545
Echinococcus multilocularis chromobox protein 1 Get druggable targets OG5_129545 All targets in OG5_129545
Trypanosoma cruzi DNA polymerase eta, putative Get druggable targets OG5_128521 All targets in OG5_128521
Leishmania major DNA polymerase eta, putative Get druggable targets OG5_128521 All targets in OG5_128521
Trypanosoma brucei DNA polymerase eta, putative Get druggable targets OG5_128521 All targets in OG5_128521
Leishmania infantum DNA polymerase eta, putative Get druggable targets OG5_128521 All targets in OG5_128521
Loa Loa (eye worm) heterochromatin protein 1 Get druggable targets OG5_129545 All targets in OG5_129545
Candida albicans similar to S. cerevisiae DNA polymerase pol-eta, involved in the bypass of distorted DNA lesions Get druggable targets OG5_128521 All targets in OG5_128521
Trichomonas vaginalis chromobox protein, putative Get druggable targets OG5_129545 All targets in OG5_129545
Echinococcus granulosus chromobox protein 1 Get druggable targets OG5_129545 All targets in OG5_129545
Brugia malayi Heterochromatin protein 1 Get druggable targets OG5_129545 All targets in OG5_129545
Candida albicans similar to S. cerevisiae DNA polymerase pol-eta, involved in the bypass of distorted DNA lesions Get druggable targets OG5_128521 All targets in OG5_128521
Echinococcus multilocularis dna polymerase eta Get druggable targets OG5_128521 All targets in OG5_128521
Leishmania mexicana Get druggable targets OG5_128521 All targets in OG5_128521
Theileria parva hypothetical protein Get druggable targets OG5_129545 All targets in OG5_129545
Echinococcus multilocularis atpase aaa+ type core atpase aaa type core Get druggable targets OG5_139225 All targets in OG5_139225
Schistosoma mansoni mixed-lineage leukemia protein mll Get druggable targets OG5_130642 All targets in OG5_130642
Toxoplasma gondii ImpB/MucB/SamB family protein Get druggable targets OG5_128521 All targets in OG5_128521
Trichomonas vaginalis chromobox protein, putative Get druggable targets OG5_129545 All targets in OG5_129545
Neospora caninum Multidomain chromatinic protein with the following architecture: 3x PHD-bromo-3xPHD-SET domain and associated cysteine cluster a Get druggable targets OG5_130642 All targets in OG5_130642
Neospora caninum Pc21g17280 protein, related Get druggable targets OG5_128521 All targets in OG5_128521
Schistosoma japonicum Chromobox protein homolog 5, putative Get druggable targets OG5_129545 All targets in OG5_129545
Loa Loa (eye worm) pre-SET domain-containing protein family protein Get druggable targets OG5_131470 All targets in OG5_131470
Leishmania braziliensis DNA polymerase eta, putative Get druggable targets OG5_128521 All targets in OG5_128521
Trypanosoma congolense DNA polymerase eta, putative Get druggable targets OG5_128521 All targets in OG5_128521
Onchocerca volvulus Get druggable targets OG5_131470 All targets in OG5_131470
Brugia malayi Pre-SET motif family protein Get druggable targets OG5_131470 All targets in OG5_131470
Leishmania mexicana DNA polymerase eta, putative Get druggable targets OG5_128521 All targets in OG5_128521
Loa Loa (eye worm) hypothetical protein Get druggable targets OG5_128521 All targets in OG5_128521
Echinococcus granulosus dna polymerase eta Get druggable targets OG5_128521 All targets in OG5_128521
Echinococcus multilocularis chromobox protein 1 Get druggable targets OG5_129545 All targets in OG5_129545
Brugia malayi ImpB/MucB/SamB family protein Get druggable targets OG5_128521 All targets in OG5_128521
Schistosoma japonicum ko:K09188 myeloid/lymphoid or mixed-lineage leukemia protein 3, putative Get druggable targets OG5_130642 All targets in OG5_130642
By sequence similarity to non orthologous known druggable targets
Species Potential target Known druggable target Length Alignment span Identity
Brugia malayi Hypothetical 65.5 kDa Trp-Asp repeats containing protein F02E8.5 inchromosome X geminin, DNA replication inhibitor 209 aa 176 aa 27.8 %
Schistosoma mansoni ferritin Ferritin light chain   175 aa 171 aa 44.4 %
Schistosoma mansoni apoferritin-2 Ferritin light chain   175 aa 142 aa 29.6 %
Schistosoma mansoni apoferritin-2 Ferritin light chain   175 aa 146 aa 28.8 %
Schistosoma japonicum Ferritin, putative Ferritin light chain   175 aa 144 aa 24.3 %
Schistosoma mansoni ferritin Ferritin light chain   175 aa 171 aa 43.9 %
Echinococcus multilocularis expressed protein Ferritin light chain   175 aa 146 aa 30.1 %
Echinococcus granulosus expressed protein Ferritin light chain   175 aa 146 aa 28.8 %
Obtained from network model

Ranking Plot

Putative Targets List

Species Potential target Raw Global Species
Loa Loa (eye worm) hypothetical protein 0.0016 0.0048 0.0083
Schistosoma mansoni thyroid hormone receptor 0.0009 0.0001 0.0002
Loa Loa (eye worm) cytoplasmic intermediate filament protein 0.0009 0.0005 0.0009
Echinococcus multilocularis pyroglutamylated rfamide peptide receptor 0.0062 0.0335 0.0335
Echinococcus multilocularis glutamate receptor subunit protein glur 0.009 0.0514 0.0514
Loa Loa (eye worm) hypothetical protein 0.0046 0.0238 0.0414
Schistosoma mansoni amine GPCR 0.0062 0.0335 0.0582
Schistosoma mansoni ferritin 0.001 0.0012 0.0021
Schistosoma mansoni 6-phosphofructokinase 0.0114 0.0665 0.1156
Brugia malayi hypothetical protein 0.0062 0.0335 0.0871
Loa Loa (eye worm) hypothetical protein 0.0062 0.0335 0.0582
Trichomonas vaginalis Heterochromatin protein, putative 0.0014 0.0034 0.0171
Echinococcus multilocularis telomerase reverse transcriptase subunit 0.0012 0.0024 0.0024
Brugia malayi Animal haem peroxidase family protein 0.0029 0.013 0.0338
Echinococcus granulosus histone lysine N methyltransferase MLL3 0.001 0.001 0.0017
Brugia malayi 6-phosphofructokinase 0.0114 0.0665 0.173
Plasmodium vivax PST-A protein 0.0019 0.0066 0.1539
Schistosoma mansoni hypothetical protein 0.0021 0.0077 0.0134
Echinococcus granulosus importin subunit beta 1 0.003 0.0139 0.0242
Onchocerca volvulus 0.0014 0.0034 0.0088
Loa Loa (eye worm) matrixin family protein 0.0014 0.0033 0.0057
Loa Loa (eye worm) animal heme peroxidase 0.0029 0.013 0.0226
Trypanosoma brucei monoglyceride lipase, putative 0.0019 0.0066 0.0386
Treponema pallidum amino acid ABC transporter, periplasmic binding protein 0.0232 0.14 1
Brugia malayi Receptor family ligand binding region containing protein 0.0046 0.0238 0.062
Loa Loa (eye worm) hypothetical protein 0.0044 0.0221 0.0385
Brugia malayi ImpB/MucB/SamB family protein 0.0054 0.0287 0.0746
Trichomonas vaginalis chromodomain-helicase-DNA-binding protein, putative 0.0018 0.006 0.0323
Loa Loa (eye worm) hypothetical protein 0.0009 0.0001 0.0002
Echinococcus multilocularis histone lysine N methyltransferase MLL3 0.0012 0.0023 0.0023
Schistosoma mansoni caspase-7 (C14 family) 0.0071 0.0394 0.0685
Echinococcus multilocularis caspase 3, apoptosis cysteine peptidase 0.0021 0.0082 0.0082
Toxoplasma gondii histone deacetylase HDAC3 0.0029 0.0131 0.2949
Trypanosoma cruzi inositol 5-phosphatase 1, putative 0.001 0.0008 0.0045
Loa Loa (eye worm) hypothetical protein 0.0062 0.0335 0.0582
Echinococcus granulosus endonuclease exonuclease phosphatase 0.001 0.0008 0.0013
Brugia malayi AMP-binding enzyme family protein 0.0025 0.0105 0.0273
Brugia malayi hypothetical protein 0.0128 0.0751 0.1953
Loa Loa (eye worm) hypothetical protein 0.0054 0.0287 0.0499
Trypanosoma cruzi GTP-binding nuclear protein rtb2, putative 0.0022 0.0088 0.0519
Trypanosoma cruzi importin beta-1 subunit, putative 0.0025 0.0103 0.0603
Trypanosoma brucei apurinic/apyrimidinic endonuclease, putative 0.0048 0.0246 0.1442
Echinococcus multilocularis glutamate receptor 2 0.0046 0.0238 0.0238
Echinococcus granulosus glutamate receptor 2 0.0137 0.0805 0.14
Trypanosoma brucei importin beta-1 subunit, putative 0.003 0.0139 0.0815
Echinococcus multilocularis DNA (apurinic or apyrimidinic site) lyase 0.0048 0.0246 0.0246
Mycobacterium tuberculosis Probable exodeoxyribonuclease III protein XthA (exonuclease III) (EXO III) (AP endonuclease VI) 0.0048 0.0246 0.1729
Mycobacterium tuberculosis Conserved hypothetical protein 0.0023 0.0094 0.0642
Echinococcus granulosus glutamate receptor ionotropic kainate 3 0.009 0.0514 0.0894
Treponema pallidum amino acid ABC transporter, periplasmic binding protein (hisJ) 0.0232 0.14 1
Trichomonas vaginalis chromodomain helicase DNA binding protein, putative 0.0017 0.0057 0.0302
Echinococcus granulosus inhibitor of apoptosis protein 0.0015 0.004 0.0069
Plasmodium falciparum exodeoxyribonuclease III, putative 0.001 0.0008 0.0181
Loa Loa (eye worm) nuclear hormone receptor family member nhr-49 0.0009 0.0001 0.0002
Leishmania major hypothetical protein, conserved 0.0053 0.0278 0.1633
Leishmania major DNA polymerase eta, putative 0.0038 0.0186 0.1091
Plasmodium vivax heterochromatin protein 1, putative 0.0014 0.0034 0.0794
Toxoplasma gondii inositol(myo)-1(or 4)-monophosphatase 2, putative 0.0037 0.0181 0.4058
Echinococcus granulosus histone lysine methyltransferase setb 0.0044 0.0221 0.0385
Brugia malayi Associated with TFs and helicases family protein 0.0014 0.0034 0.0088
Echinococcus granulosus chromobox protein 2 0.0014 0.0034 0.0059
Trichomonas vaginalis chromodomain helicase DNA binding protein, putative 0.0022 0.0083 0.0454
Echinococcus granulosus baculoviral IAP repeat containing protein 0.0015 0.004 0.0069
Toxoplasma gondii 4'-phosphopantetheinyl transferase superfamily protein 0.0025 0.0102 0.2286
Onchocerca volvulus 0.0062 0.0335 0.0871
Mycobacterium tuberculosis Probable fatty-acid-CoA ligase FadD2 (fatty-acid-CoA synthetase) (fatty-acid-CoA synthase) 0.0025 0.0105 0.0721
Echinococcus multilocularis neutral sphingomyelinase 0.001 0.0008 0.0008
Echinococcus granulosus lipoxygenase domain containing protein 0.0028 0.0123 0.0214
Mycobacterium ulcerans ATP-dependent Clp protease proteolytic subunit 0.0077 0.0428 0.3033
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0062 0.0335 0.0582
Brugia malayi Protein cec-1. 0.0014 0.0034 0.0088
Brugia malayi Endonuclease/Exonuclease/phosphatase family protein 0.001 0.0008 0.002
Trichomonas vaginalis conserved hypothetical protein 0.0018 0.006 0.0323
Schistosoma mansoni peptide (FMRFamide/somatostatin)-like receptor 0.0062 0.0335 0.0582
Loa Loa (eye worm) glutamate receptor 0.0046 0.0238 0.0414
Loa Loa (eye worm) hypothetical protein 0.0029 0.0131 0.0228
Brugia malayi Heterochromatin protein 1 0.0084 0.0475 0.1237
Loa Loa (eye worm) hypothetical protein 0.0015 0.004 0.0069
Trypanosoma cruzi Endonuclease/Exonuclease/phosphatase family, putative 0.001 0.0008 0.0045
Trypanosoma brucei PAB1-binding protein , putative 0.0053 0.0278 0.1633
Onchocerca volvulus 0.001 0.0008 0.002
Trypanosoma cruzi mitogen activated protein kinase 2, putative 0.0015 0.004 0.0235
Loa Loa (eye worm) RNA binding protein 0.0069 0.0382 0.0664
Mycobacterium ulcerans aldehyde dehydrogenase 0.0079 0.0445 0.316
Trypanosoma cruzi mitogen activated protein kinase 4, putative 0.0015 0.004 0.0235
Schistosoma mansoni ran 0.0022 0.0088 0.0154
Loa Loa (eye worm) follicle stimulating hormone receptor 0.0062 0.0335 0.0582
Echinococcus multilocularis rhodopsin orphan GPCR 0.0062 0.0335 0.0335
Echinococcus granulosus thymidylate synthase 0.0047 0.0244 0.0425
Leishmania major extracellular receptor, putative 0.0046 0.0238 0.1398
Onchocerca volvulus 0.0016 0.0048 0.0124
Loa Loa (eye worm) nuclear hormone receptor family member nhr-31 0.0009 0.0001 0.0002
Trypanosoma brucei DNA polymerase kappa, putative 0.0016 0.0048 0.0284
Trypanosoma brucei metacaspase 0.0021 0.0082 0.0479
Echinococcus multilocularis FTZ F1 nuclear receptor protein 0.0009 0.0001 0.0001
Plasmodium falciparum carbon catabolite repressor protein 4, putative 0.001 0.0008 0.0181
Mycobacterium tuberculosis Probable chain -fatty-acid-CoA ligase FadD13 (fatty-acyl-CoA synthetase) 0.0025 0.0105 0.0721
Schistosoma mansoni zinc finger protein 0.001 0.0009 0.0016
Schistosoma mansoni lipoxygenase 0.0167 0.0998 0.1736
Mycobacterium tuberculosis Probable exported protein 0.001 0.0008 0.0025
Loa Loa (eye worm) hypothetical protein 0.0016 0.0048 0.0083
Brugia malayi Unidentified vitellogenin-linked transcript protein 6, putative 0.0062 0.0335 0.0871
Loa Loa (eye worm) 6-phosphofructokinase 0.0114 0.0665 0.1156
Schistosoma mansoni glutamate receptor NMDA 0.0501 0.3091 0.5374
Loa Loa (eye worm) endonuclease/Exonuclease/phosphatase 0.001 0.0008 0.0013
Trichomonas vaginalis phosphofructokinase, putative 0.0031 0.0141 0.0787
Brugia malayi hypothetical protein 0.0028 0.0123 0.0321
Echinococcus multilocularis serine threonine protein kinase 0.0015 0.0043 0.0043
Schistosoma mansoni chromodomain helicase DNA binding protein 0.0017 0.0051 0.0089
Brugia malayi sulfakinin receptor protein 0.0062 0.0335 0.0871
Brugia malayi 6-phosphofructokinase 0.0114 0.0665 0.1729
Echinococcus multilocularis chromodomain helicase DNA binding protein 1 0.0014 0.0034 0.0034
Mycobacterium ulcerans long-chain-fatty-acid--CoA ligase 0.0025 0.0105 0.0721
Entamoeba histolytica histone deacetylase, putative 0.0029 0.0131 0.1882
Leishmania major DNA polymerase kappa, putative,DNA polymerase IV, putative 0.0023 0.0094 0.055
Plasmodium vivax hypothetical protein, conserved 0.0016 0.0048 0.1117
Onchocerca volvulus 0.0062 0.0335 0.0871
Brugia malayi Animal haem peroxidase family protein 0.0029 0.013 0.0338
Loa Loa (eye worm) hypothetical protein 0.0062 0.0335 0.0582
Mycobacterium tuberculosis Possible DNA-damage-inducible protein P DinP (DNA polymerase V) (pol IV 2) (DNA nucleotidyltransferase (DNA-directed)) 0.0023 0.0094 0.0642
Loa Loa (eye worm) hypothetical protein 0.0028 0.0123 0.0214
Schistosoma mansoni ap endonuclease 0.0048 0.0246 0.0427
Mycobacterium tuberculosis Conserved protein 0.0016 0.0048 0.0312
Mycobacterium tuberculosis Bacterioferritin BfrB 0.001 0.0012 0.0055
Loa Loa (eye worm) hypothetical protein 0.0062 0.0335 0.0582
Echinococcus multilocularis L aminoadipate semialdehyde 0.0087 0.0496 0.0496
Onchocerca volvulus 0.0029 0.013 0.0338
Schistosoma mansoni hypothetical protein 0.0382 0.2345 0.4078
Schistosoma mansoni apoferritin-2 0.001 0.0012 0.0021
Loa Loa (eye worm) hypothetical protein 0.0009 0.0005 0.0009
Brugia malayi Glutamate receptor 1 precursor 0.009 0.0514 0.1338
Leishmania major mitogen activated protein kinase, putative,map kinase, putative 0.0015 0.004 0.0235
Echinococcus multilocularis muscleblind protein 0.005 0.0263 0.0263
Schistosoma mansoni biogenic amine receptor 0.0062 0.0335 0.0582
Echinococcus multilocularis orexin receptor type 2 0.0062 0.0335 0.0335
Echinococcus granulosus transcription factor Dp 1 0.004 0.02 0.0347
Loa Loa (eye worm) hypothetical protein 0.0016 0.0048 0.0083
Loa Loa (eye worm) hypothetical protein 0.0029 0.013 0.0226
Brugia malayi chromobox protein homolog 3 0.0047 0.0243 0.0633
Loa Loa (eye worm) hypothetical protein 0.0029 0.013 0.0226
Treponema pallidum exodeoxyribonuclease (exoA) 0.0048 0.0246 0.1708
Echinococcus multilocularis aldehyde dehydrogenase, mitochondrial 0.0079 0.0445 0.0445
Schistosoma mansoni FTZ-F1 nuclear receptor-like protein 0.0009 0.0001 0.0002
Echinococcus multilocularis glutamate receptor 2 0.0137 0.0805 0.0805
Echinococcus granulosus traf and tnf receptor associated protein 0.001 0.0008 0.0013
Trypanosoma cruzi dihydrofolate reductase-thymidylate synthase, putative 0.0023 0.0089 0.0521
Plasmodium vivax hypothetical protein, conserved 0.001 0.0008 0.0181
Echinococcus granulosus guanine nucleotide binding protein Gs subunit 0.0101 0.058 0.1009
Onchocerca volvulus 0.0016 0.0048 0.0124
Loa Loa (eye worm) CCR4-NOT transcription complex subunit 6 family protein 0.001 0.0008 0.0013
Echinococcus granulosus fmrfamide receptor 0.0062 0.0335 0.0582
Trichomonas vaginalis conserved hypothetical protein 0.0047 0.0243 0.1373
Loa Loa (eye worm) hypothetical protein 0.0062 0.0335 0.0582
Brugia malayi putative neuropeptide receptor NPR1 0.0062 0.0335 0.0871
Loa Loa (eye worm) hypothetical protein 0.0621 0.3843 0.6683
Echinococcus multilocularis apoptotic protease activating factor 1 0.005 0.026 0.026
Trypanosoma brucei DNA polymerase kappa, putative 0.0023 0.0094 0.055
Trypanosoma brucei DNA polymerase kappa, putative 0.0023 0.0094 0.055
Brugia malayi larval opioid receptor 0.0062 0.0335 0.0871
Trypanosoma brucei Endonuclease/Exonuclease/phosphatase family, putative 0.001 0.0008 0.0045
Schistosoma mansoni polycystin 1-related 0.0028 0.0123 0.0214
Schistosoma mansoni caspase-7 (C14 family) 0.0021 0.0082 0.0142
Echinococcus granulosus geminin 0.0382 0.2345 0.4078
Loa Loa (eye worm) steroid hormone receptor 0.0009 0.0001 0.0002
Loa Loa (eye worm) endonuclease/Exonuclease/phosphatase 0.001 0.0008 0.0013
Leishmania major aldehyde dehydrogenase, mitochondrial precursor 0.0079 0.0445 0.2614
Loa Loa (eye worm) hypothetical protein 0.0029 0.013 0.0226
Brugia malayi metabotropic glutamate receptor type 2 0.0046 0.0238 0.062
Trypanosoma brucei Endonuclease/Exonuclease/phosphatase family, putative 0.001 0.0008 0.0045
Trichomonas vaginalis histone deacetylase, putative 0.0029 0.0131 0.073
Brugia malayi phosphofructokinase 0.0114 0.0665 0.1729
Trichomonas vaginalis conserved hypothetical protein 0.0021 0.0082 0.0444
Schistosoma mansoni Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) 0.0101 0.058 0.1009
Brugia malayi hypothetical protein 0.0062 0.0335 0.0871
Trichomonas vaginalis conserved hypothetical protein 0.0033 0.0157 0.0877
Echinococcus multilocularis hepatocyte nuclear factor 4 alpha 0.0009 0.0001 0.0001
Entamoeba histolytica hypothetical protein 0.0014 0.0034 0.0399
Trichomonas vaginalis chromodomain helicase DNA binding protein, putative 0.0022 0.0083 0.0454
Echinococcus granulosus dna polymerase eta 0.0054 0.0287 0.0499
Trichomonas vaginalis CMGC family protein kinase 0.0015 0.004 0.0206
Echinococcus granulosus neuropeptide receptor 0.0062 0.0335 0.0582
Loa Loa (eye worm) hypothetical protein 0.0046 0.0238 0.0414
Echinococcus granulosus Glutamate receptor ionotropic kainate 2 0.0137 0.0805 0.14
Brugia malayi RNA, U transporter 1 0.0087 0.0492 0.1279
Trichomonas vaginalis chromodomain-helicase-DNA-binding protein, putative 0.0022 0.0083 0.0454
Brugia malayi Corticotropin releasing factor receptor 2 precursor, putative 0.0065 0.0356 0.0927
Loa Loa (eye worm) ImpB/MucB/SamB family protein 0.0023 0.0094 0.0163
Echinococcus granulosus matrix metallopeptidase 7 M10 family 0.0022 0.0087 0.0151
Brugia malayi hypothetical protein 0.0034 0.0161 0.0419
Plasmodium vivax metacaspase 1, putative 0.0021 0.0082 0.1909
Echinococcus granulosus intermediate filament protein 0.0017 0.0055 0.0096
Loa Loa (eye worm) hypothetical protein 0.0062 0.0335 0.0582
Onchocerca volvulus 0.0287 0.1747 0.4545
Trypanosoma brucei protein kinase, putative 0.0015 0.004 0.0235
Brugia malayi Dihydrofolate reductase 0.0019 0.0069 0.0178
Entamoeba histolytica hypothetical protein 0.0025 0.0102 0.1432
Onchocerca volvulus 0.0087 0.0496 0.1291
Loa Loa (eye worm) hypothetical protein 0.0014 0.0034 0.0059
Plasmodium vivax bifunctional dihydrofolate reductase-thymidylate synthase, putative 0.0067 0.0365 0.8546
Schistosoma mansoni terminal deoxycytidyl transferase 0.0023 0.0094 0.0163
Brugia malayi Animal haem peroxidase family protein 0.0029 0.013 0.0338
Mycobacterium tuberculosis Hypothetical protein 0.0023 0.0089 0.0606
Echinococcus multilocularis fmrfamide receptor 0.0062 0.0335 0.0335
Loa Loa (eye worm) tyrosyl-DNA phosphodiesterase 0.0069 0.0383 0.0666
Schistosoma mansoni ferritin light chain 0.001 0.0012 0.0021
Echinococcus multilocularis Ribosomal protein S1, RNA binding domain 0.009 0.0514 0.0514
Brugia malayi RE15519p 0.0062 0.0335 0.0871
Onchocerca volvulus 0.0016 0.0048 0.0124
Trichomonas vaginalis conserved hypothetical protein 0.0019 0.0066 0.0354
Leishmania major histone deacetylase, putative 0.0029 0.0131 0.0771
Brugia malayi Intermediate filament tail domain containing protein 0.0017 0.0055 0.0144
Echinococcus multilocularis chromobox protein 2 0.0014 0.0034 0.0034
Loa Loa (eye worm) G-protein coupled receptor 0.0062 0.0335 0.0582
Mycobacterium tuberculosis Probable ATP-dependent CLP protease proteolytic subunit 2 ClpP2 (endopeptidase CLP 2) 0.005 0.0262 0.1848
Brugia malayi CHD4 protein 0.0017 0.0051 0.0133
Loa Loa (eye worm) hypothetical protein 0.0062 0.0335 0.0582
Loa Loa (eye worm) hypothetical protein 0.0062 0.0335 0.0582
Loa Loa (eye worm) hypothetical protein 0.0009 0.0004 0.0007
Schistosoma mansoni hypothetical protein 0.0015 0.004 0.0069
Brugia malayi Endonuclease/Exonuclease/phosphatase family protein 0.001 0.0008 0.002
Leishmania major histone deacetylase, putative 0.0029 0.0131 0.0771
Loa Loa (eye worm) histone methyltransferase 0.0012 0.0023 0.004
Echinococcus multilocularis sex peptide receptor 0.0062 0.0335 0.0335
Schistosoma mansoni hypothetical protein 0.0014 0.0034 0.0059
Brugia malayi dihydrofolate reductase family protein 0.0019 0.0069 0.0178
Onchocerca volvulus Steroid hormone receptor family member cnr14 homolog 0.0009 0.0001 0.0003
Trypanosoma cruzi DNA polymerase kappa, putative 0.0023 0.0094 0.055
Echinococcus granulosus Glutamate receptor ionotropic kainate 2 0.0137 0.0805 0.14
Echinococcus granulosus g protein linked acetylcholine receptor gar 2a 0.0062 0.0335 0.0582
Trichomonas vaginalis chromodomain helicase DNA binding protein, putative 0.0022 0.0083 0.0454
Brugia malayi Nuclear hormone receptor family member nhr-40 0.0009 0.0001 0.0003
Trichomonas vaginalis chromobox protein, putative 0.0014 0.0034 0.0171
Brugia malayi M-phase phosphoprotein, mpp8 0.0014 0.0034 0.0088
Entamoeba histolytica deoxycytidyl transferase, putative 0.0023 0.0094 0.131
Brugia malayi Bromodomain containing protein 0.0015 0.0044 0.0114
Loa Loa (eye worm) hypothetical protein 0.0065 0.0356 0.0619
Chlamydia trachomatis fructose-6-phosphate phosphotransferase 0.0031 0.0141 0.057
Echinococcus multilocularis Chromo domain 0.0014 0.0034 0.0034
Trypanosoma cruzi mitogen-activated protein kinase 11, putative 0.0015 0.004 0.0235
Echinococcus multilocularis serotonin receptor 0.0925 0.5751 0.5751
Trypanosoma cruzi extracellular receptor, putative 0.0046 0.0238 0.1398
Loa Loa (eye worm) receptor family ligand binding region containing protein 0.0046 0.0238 0.0414
Echinococcus multilocularis importin subunit beta 1 0.003 0.0139 0.0139
Mycobacterium ulcerans hypothetical protein 0.0025 0.0105 0.0721
Brugia malayi Histone deacetylase 1 0.0029 0.0131 0.0342
Trichomonas vaginalis chromodomain-helicase-DNA-binding protein, putative 0.0014 0.0034 0.0171
Echinococcus multilocularis growth hormone secretagogue receptor type 1 0.0062 0.0335 0.0335
Leishmania major hypothetical protein, conserved 0.001 0.0008 0.0045
Schistosoma mansoni ferritin light chain 0.001 0.0012 0.0021
Onchocerca volvulus 0.0062 0.0335 0.0871
Echinococcus multilocularis glutamate receptor NMDA 0.0364 0.2233 0.2233
Schistosoma mansoni tar DNA-binding protein 0.0069 0.0382 0.0664
Echinococcus multilocularis NMDA receptor 0.009 0.0514 0.0514
Loa Loa (eye worm) pre-SET domain-containing protein family protein 0.0252 0.1529 0.2659
Mycobacterium leprae possible inositol monophosphatase SubH (IMPase) (inositol-1-phosphatase) (I-1-Pase ). 0.0033 0.0156 0.2214
Schistosoma mansoni peptide (allatostatin)-like receptor 0.0062 0.0335 0.0582
Schistosoma mansoni tar DNA-binding protein 0.0069 0.0382 0.0664
Echinococcus multilocularis Glutamate receptor, ionotropic kainate 2 0.0137 0.0805 0.0805
Echinococcus multilocularis inositol monophosphatase 1 0.0037 0.0181 0.0181
Echinococcus granulosus G protein coupled 5 hydroxytryptamine receptor 0.0062 0.0335 0.0582
Echinococcus granulosus dro:myosuppressin receptor 0.0062 0.0335 0.0582
Mycobacterium ulcerans acyl-CoA synthetase 0.0025 0.0105 0.0721
Echinococcus multilocularis histone lysine N methyltransferase MLL3 0.001 0.001 0.001
Echinococcus granulosus FTZ F1 nuclear receptor protein 0.0009 0.0001 0.0002
Trichomonas vaginalis phosphofructokinase, putative 0.0031 0.0141 0.0787
Trichomonas vaginalis phosphofructokinase, putative 0.0114 0.0665 0.3789
Trichomonas vaginalis phosphofructokinase, putative 0.0114 0.0665 0.3789
Entamoeba histolytica Ran family GTPase 0.0022 0.0088 0.1228
Echinococcus multilocularis RUN 0.0028 0.0123 0.0123
Trypanosoma brucei Metacaspase-4 0.0021 0.0082 0.0479
Toxoplasma gondii histone lysine methyltransferase SET/SUV39 0.0037 0.0178 0.4007
Echinococcus granulosus tm gpcr rhodopsin 0.0062 0.0335 0.0582
Onchocerca volvulus Peroxidase homolog 0.0029 0.013 0.0338
Brugia malayi Cell death protein 3 precursor 0.0071 0.0394 0.1025
Trypanosoma brucei RNA editing exonuclease 2 0.001 0.0008 0.0045
Trypanosoma brucei unspecified product 0.0016 0.0048 0.0284
Echinococcus multilocularis G protein coupled 5 hydroxytryptamine receptor 0.0062 0.0335 0.0335
Plasmodium falciparum heterochromatin protein 1 0.0014 0.0034 0.0794
Echinococcus granulosus mitogen activated protein kinase 3 0.0015 0.004 0.007
Loa Loa (eye worm) hypothetical protein 0.0009 0.0001 0.0002
Schistosoma mansoni amine GPCR 0.0062 0.0335 0.0582
Trichomonas vaginalis Clan SC, family S33, methylesterase-like serine peptidase 0.0019 0.0066 0.0354
Echinococcus granulosus tar DNA binding protein 0.0069 0.0382 0.0664
Trichomonas vaginalis chromobox protein, putative 0.0051 0.0266 0.1502
Schistosoma mansoni cpg binding protein 0.0035 0.0165 0.0287
Echinococcus multilocularis histone deacetylase 1 0.0029 0.0131 0.0131
Loa Loa (eye worm) hypothetical protein 0.0029 0.013 0.0226
Echinococcus granulosus receptor type guanylyl cyclase 0.0046 0.0238 0.0414
Echinococcus multilocularis rhodopsin orphan GPCR 0.0062 0.0335 0.0335
Echinococcus granulosus apoptotic protease activating factor 1 0.005 0.026 0.0452
Echinococcus multilocularis tachykinin peptides receptor 99D 0.0062 0.0335 0.0335
Echinococcus granulosus nuclear receptor 2DBD gamma 0.0009 0.0001 0.0002
Plasmodium falciparum lysophospholipase, putative 0.0019 0.0066 0.1539
Entamoeba histolytica hypothetical protein 0.0014 0.0034 0.0399
Echinococcus granulosus cadherin EGF LAG seven pass G type receptor 0.0021 0.0077 0.0134
Toxoplasma gondii 4'-phosphopantetheinyl transferase domain-containing protein 0.0025 0.0102 0.2286
Loa Loa (eye worm) hypothetical protein 0.0029 0.013 0.0226
Echinococcus granulosus Ribosomal protein S1 RNA binding domain 0.009 0.0514 0.0894
Loa Loa (eye worm) hypothetical protein 0.0062 0.0335 0.0582
Trypanosoma cruzi cytochrome P450, putative 0.0013 0.0029 0.0168
Echinococcus multilocularis arachidonate 5 lipoxygenase 0.0167 0.0998 0.0998
Loa Loa (eye worm) hypothetical protein 0.0019 0.0065 0.0113
Leishmania major inositol/phosphatidylinositol phosphatase, putative 0.001 0.0008 0.0045
Echinococcus granulosus lamin 0.0017 0.0055 0.0096
Echinococcus multilocularis receptor type guanylyl cyclase 0.0046 0.0238 0.0238
Echinococcus granulosus Chromo domain 0.0014 0.0034 0.0059
Loa Loa (eye worm) nucleolar RNA-associated protein alpha 0.0326 0.199 0.3461
Brugia malayi Inhibitor of Apoptosis domain containing protein 0.0015 0.004 0.0103
Loa Loa (eye worm) hypothetical protein 0.0019 0.0065 0.0113
Schistosoma mansoni ferritin 0.001 0.0012 0.0021
Leishmania major RNA-editing complex protein MP100, putative 0.001 0.0008 0.0045
Echinococcus multilocularis neuropeptide receptor 0.0062 0.0335 0.0335
Wolbachia endosymbiont of Brugia malayi ATP-dependent Clp protease proteolytic subunit 0.0077 0.0428 1
Loa Loa (eye worm) hypothetical protein 0.0062 0.0335 0.0582
Schistosoma mansoni neuropeptide f receptor 76f 0.0062 0.0335 0.0582
Loa Loa (eye worm) hypothetical protein 0.0062 0.0335 0.0582
Plasmodium falciparum ATP-dependent Clp protease proteolytic subunit 0.0077 0.0428 1
Brugia malayi mucosa associated lymphoid tissue lymphoma translocation protein 1 0.0021 0.0082 0.0212
Loa Loa (eye worm) hypothetical protein 0.0016 0.0048 0.0083
Loa Loa (eye worm) intermediate filament protein 0.0017 0.0055 0.0096
Entamoeba histolytica chromodomain-helicase-DNA-binding protein, putative 0.0014 0.0034 0.0399
Loa Loa (eye worm) histone deacetylase 1 0.0029 0.0131 0.0228
Onchocerca volvulus Matrix metalloproteinase homolog 0.0014 0.0033 0.0085
Echinococcus granulosus biogenic amine 5HT receptor 0.0062 0.0335 0.0582
Mycobacterium ulcerans exodeoxyribonuclease III protein XthA 0.0048 0.0246 0.1729
Schistosoma mansoni chromobox protein-related (chromobox 1) (heterochromatin 1) 0.0014 0.0034 0.0059
Trichomonas vaginalis D-aminoacylase, putative 0.0016 0.0048 0.025
Brugia malayi Endonuclease/Exonuclease/phosphatase family protein 0.001 0.0008 0.002
Loa Loa (eye worm) hypothetical protein 0.0062 0.0335 0.0582
Trypanosoma brucei DNA polymerase kappa, putative 0.0023 0.0094 0.055
Echinococcus multilocularis lamin 0.0017 0.0055 0.0055
Schistosoma mansoni cpg binding protein 0.0037 0.0182 0.0317
Onchocerca volvulus Peroxidase homolog 0.0029 0.013 0.0338
Loa Loa (eye worm) hypothetical protein 0.0014 0.0034 0.0059
Loa Loa (eye worm) hypothetical protein 0.0029 0.013 0.0226
Loa Loa (eye worm) hypothetical protein 0.0062 0.0335 0.0582
Echinococcus multilocularis cpg binding protein 0.0037 0.0182 0.0182
Echinococcus multilocularis nuclear receptor 2DBD gamma 0.0009 0.0001 0.0001
Loa Loa (eye worm) hypothetical protein 0.0925 0.5751 1
Loa Loa (eye worm) hypothetical protein 0.0014 0.0034 0.0059
Brugia malayi hypothetical protein 0.0009 0.0004 0.0011
Echinococcus multilocularis Chromobox protein 3 0.0014 0.0034 0.0034
Loa Loa (eye worm) CXXC zinc finger family protein 0.0035 0.0165 0.0287
Echinococcus granulosus neuropeptide receptor 0.0062 0.0335 0.0582
Echinococcus granulosus Protein kinase C brain isozyme 0.0017 0.0055 0.0095
Echinococcus granulosus bromodomain adjacent to zinc finger domain 0.0026 0.011 0.0191
Trichomonas vaginalis phosphofructokinase, putative 0.0031 0.0141 0.0787
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0062 0.0335 0.0582
Trypanosoma cruzi PAB1-binding protein , putative 0.0053 0.0278 0.1633
Echinococcus granulosus 7TM GPCR rhodopsin 0.0062 0.0335 0.0582
Mycobacterium ulcerans acyl-CoA synthetase 0.0025 0.0105 0.0721
Brugia malayi metabotropic GABA-B receptor subtype 2 0.0046 0.0238 0.062
Echinococcus multilocularis COUP TF:Svp nuclear hormone receptor 0.0009 0.0001 0.0001
Echinococcus multilocularis lamin dm0 0.0017 0.0055 0.0055
Schistosoma mansoni ocrl type II inositol 5-phosphatase 0.001 0.0008 0.0013
Brugia malayi GTP-binding nuclear protein RAN/TC4 0.0022 0.0088 0.023
Brugia malayi Pre-SET motif family protein 0.0037 0.0178 0.0464
Echinococcus granulosus GTP binding nuclear protein Ran 0.0022 0.0088 0.0154
Onchocerca volvulus 0.001 0.0008 0.002
Echinococcus granulosus ecdysone induced protein 78C 0.0009 0.0001 0.0002
Loa Loa (eye worm) hypothetical protein 0.0014 0.0035 0.0061
Loa Loa (eye worm) hypothetical protein 0.0009 0.0001 0.0002
Brugia malayi PHD-finger family protein 0.0012 0.0022 0.0058
Trypanosoma cruzi apurinic/apyrimidinic endonuclease 0.0048 0.0246 0.1442
Echinococcus multilocularis musashi 0.0017 0.0055 0.0055
Echinococcus multilocularis caspase 8 0.0021 0.0082 0.0082
Schistosoma mansoni metabotropic glutamate receptor 0.0046 0.0238 0.0414
Brugia malayi hypothetical protein 0.0062 0.0335 0.0871
Mycobacterium leprae PROBABLE FATTY-ACID-CoA LIGASE FADD7 (FATTY-ACID-CoA SYNTHETASE) (FATTY-ACID-CoA SYNTHASE) 0.0025 0.0105 0.1426
Brugia malayi aminoadipate-semialdehyde dehydrogenase-phosphopantetheinyl transferase 0.0087 0.0496 0.1291
Brugia malayi hypothetical protein 0.0053 0.0278 0.0724
Brugia malayi Inositol-1 0.0037 0.0181 0.047
Trichomonas vaginalis histone deacetylase, putative 0.0029 0.0131 0.073
Echinococcus multilocularis guanine nucleotide binding protein G(s) subunit 0.0101 0.058 0.058
Leishmania major 4-coumarate:coa ligase-like protein 0.0025 0.0105 0.0616
Mycobacterium tuberculosis Probable glutamine-binding lipoprotein GlnH (GLNBP) 0.0232 0.14 1
Entamoeba histolytica tyrosyl-DNA phosphodiesterase, putative 0.0069 0.0383 0.5713
Trichomonas vaginalis carbon catabolite repressor protein, putative 0.001 0.0008 0.002
Echinococcus granulosus zinc finger protein 0.001 0.0009 0.0016
Trypanosoma brucei Inositol phosphosphingolipids phospholipase C 0.001 0.0008 0.0045
Schistosoma mansoni thyrotropin-releasing hormone receptor 0.0062 0.0335 0.0582
Loa Loa (eye worm) hypothetical protein 0.0046 0.0238 0.0414
Trypanosoma cruzi mitochondrial protein 99, putative 0.001 0.0008 0.0045
Brugia malayi nuclear receptor NHR-88 0.0009 0.0001 0.0003
Brugia malayi follicle stimulating hormone receptor 0.0062 0.0335 0.0871
Plasmodium vivax 6-phosphofructokinase, putative 0.0031 0.0141 0.3304
Brugia malayi Protein kinase c protein 2 0.0015 0.0039 0.0101
Trypanosoma cruzi Endonuclease/Exonuclease/phosphatase family, putative 0.001 0.0008 0.0045
Trichomonas vaginalis chromodomain helicase DNA binding protein, putative 0.0022 0.0083 0.0454
Echinococcus multilocularis matrix metallopeptidase 7 (M10 family) 0.0022 0.0087 0.0087
Entamoeba histolytica hypothetical protein 0.0043 0.022 0.3233
Onchocerca volvulus 0.0062 0.0335 0.0871
Mycobacterium leprae conserved hypothetical protein 0.0016 0.0048 0.0551
Toxoplasma gondii exonuclease III APE 0.0048 0.0246 0.5515
Mycobacterium leprae POSSIBLE LYSOPHOSPHOLIPASE 0.0019 0.0066 0.0827
Trichomonas vaginalis Clan SC, family S33, methylesterase-like serine peptidase 0.0019 0.0066 0.0354
Trichomonas vaginalis 6-phosphofructokinase, putative 0.0031 0.0141 0.0787
Loa Loa (eye worm) hypothetical protein 0.0062 0.0335 0.0582
Echinococcus granulosus beta LACTamase domain containing family member 0.0016 0.0048 0.0083
Onchocerca volvulus Cell death protein 3 homolog 0.0071 0.0394 0.1025
Echinococcus multilocularis neuropeptides capa receptor 0.0062 0.0335 0.0335
Loa Loa (eye worm) CYP4Cod1 0.0013 0.0029 0.005
Giardia lamblia Pyrophosphate-fructose 6-phosphate 1-phosphotransferase alpha subunit 0.0031 0.0141 0.5677
Brugia malayi Melatonin receptor type 1A 0.0062 0.0335 0.0871
Echinococcus granulosus metabotropic glutamate receptor 5 0.0046 0.0238 0.0414
Echinococcus granulosus biogenic amine 5HT receptor 0.0925 0.5751 1
Schistosoma mansoni histamine h1 receptor 0.0062 0.0335 0.0582
Wolbachia endosymbiont of Brugia malayi exonuclease III 0.0048 0.0246 0.5624
Entamoeba histolytica hypothetical protein 0.0043 0.022 0.3233
Mycobacterium tuberculosis Probable fatty-acid-CoA ligase FadD5 (fatty-acid-CoA synthetase) (fatty-acid-CoA synthase) 0.0018 0.0059 0.039
Brugia malayi Nuclear hormone receptor family member nhr-25 0.0009 0.0001 0.0003
Schistosoma mansoni family S12 unassigned peptidase (S12 family) 0.0016 0.0048 0.0083
Trypanosoma cruzi DNA polymerase kappa, putative 0.0023 0.0094 0.055
Echinococcus granulosus rhodopsin orphan GPCR 0.0062 0.0335 0.0582
Mycobacterium ulcerans aldehyde dehydrogenase 0.0079 0.0445 0.316
Echinococcus granulosus protein kinase C gamma type 0.0015 0.0043 0.0075
Trypanosoma brucei unspecified product 0.0023 0.0094 0.055
Brugia malayi hypothetical protein 0.005 0.026 0.0676
Brugia malayi Bromodomain containing protein 0.0032 0.0148 0.0385
Loa Loa (eye worm) hypothetical protein 0.0087 0.0496 0.0863
Brugia malayi Ligand-binding domain of nuclear hormone receptor family protein 0.0009 0.0001 0.0003
Toxoplasma gondii 6-phosphofructokinase 0.0031 0.0141 0.3172
Entamoeba histolytica acyl-CoA synthetase, putative 0.0025 0.0105 0.1479
Trypanosoma cruzi monoglyceride lipase, putative 0.0019 0.0066 0.0386
Trypanosoma brucei importin beta-1 subunit, putative 0.003 0.0139 0.0815
Echinococcus granulosus glutamate receptor NMDA 0.0364 0.2233 0.3883
Echinococcus multilocularis metabotropic glutamate receptor 5 0.0046 0.0238 0.0238
Loa Loa (eye worm) hypothetical protein 0.001 0.0008 0.0013
Trichomonas vaginalis CMGC family protein kinase 0.0015 0.004 0.0206
Entamoeba histolytica hypothetical protein 0.0025 0.0103 0.1446
Brugia malayi Hemopexin family protein 0.0009 0.0002 0.0005
Loa Loa (eye worm) hypothetical protein 0.0062 0.0335 0.0582
Schistosoma mansoni family S12 unassigned peptidase (S12 family) 0.0016 0.0048 0.0083
Brugia malayi Muscleblind-like protein 0.005 0.0263 0.0685
Toxoplasma gondii ICE family protease (caspase) p20 domain-containing protein 0.0021 0.0082 0.1833
Mycobacterium ulcerans fatty-acid-CoA ligase 0.0025 0.0105 0.0721
Echinococcus granulosus chromodomain helicase DNA binding protein 1 0.0014 0.0034 0.0059
Onchocerca volvulus Peroxidasin homolog 0.0029 0.013 0.0338
Trypanosoma brucei tyrosyl-DNA Phosphodiesterase (Tdp1), putative 0.0069 0.0383 0.2248
Trypanosoma brucei metacaspase MCA3 0.0021 0.0082 0.0479
Schistosoma mansoni biogenic amine (5HT) receptor 0.0062 0.0335 0.0582
Loa Loa (eye worm) hypothetical protein 0.0334 0.204 0.3548
Mycobacterium ulcerans long-chain-fatty-acid-CoA ligase 0.0025 0.0105 0.0721
Echinococcus granulosus Ataxin 2 N terminaldomain containing protein 0.0024 0.0096 0.0167
Schistosoma mansoni glutamate receptor kainate 0.009 0.0514 0.0894
Trypanosoma cruzi mitogen-activated protein kinase 11, putative 0.0015 0.004 0.0235
Schistosoma mansoni hypothetical protein 0.0021 0.0077 0.0134
Brugia malayi G-protein coupled receptor 0.0062 0.0335 0.0871
Echinococcus multilocularis rhodopsin orphan GPCR 0.0062 0.0335 0.0335
Echinococcus multilocularis inhibitor of apoptosis protein 0.0015 0.004 0.004
Schistosoma mansoni hypothetical protein 0.0062 0.0335 0.0582
Echinococcus multilocularis diuretic hormone 44 receptor GPRdih2 0.0021 0.0077 0.0077
Schistosoma mansoni hypothetical protein 0.009 0.0514 0.0894
Schistosoma mansoni neuropeptide receptor 0.0062 0.0335 0.0582
Schistosoma mansoni chromobox protein 0.0014 0.0034 0.0059
Echinococcus multilocularis nuclear receptor 2DBD gamma 0.0009 0.0001 0.0001
Echinococcus granulosus hepatocyte nuclear factor 4 alpha 0.0009 0.0001 0.0002
Brugia malayi Animal haem peroxidase family protein 0.0029 0.013 0.0338
Brugia malayi Importin beta-1 subunit 0.003 0.0139 0.0361
Echinococcus granulosus peptidase Clp S14 family 0.005 0.0262 0.0456
Trichomonas vaginalis chromodomain-helicase-DNA-binding protein, putative 0.0014 0.0034 0.0171
Schistosoma mansoni neuropeptide receptor 0.0062 0.0335 0.0582
Loa Loa (eye worm) hypothetical protein 0.0016 0.005 0.0087
Brugia malayi Doublecortin family protein 0.0028 0.0123 0.0321
Trichomonas vaginalis penicillin-binding protein, putative 0.0016 0.0048 0.025
Echinococcus multilocularis Protein kinase C, brain isozyme 0.0017 0.0055 0.0055
Schistosoma mansoni hypothetical protein 0.0021 0.0077 0.0134
Loa Loa (eye worm) hypothetical protein 0.0062 0.0335 0.0582
Loa Loa (eye worm) RGC/RGC protein kinase 0.0046 0.0238 0.0414
Trichomonas vaginalis chromodomain helicase DNA binding protein, putative 0.0014 0.0034 0.0171
Brugia malayi Cytochrome P450 family protein 0.0013 0.0029 0.0075
Toxoplasma gondii aldehyde dehydrogenase 0.0079 0.0445 1
Loa Loa (eye worm) TYRA-2 protein 0.0062 0.0335 0.0582
Echinococcus multilocularis Glutamate receptor, ionotropic kainate 2 0.0137 0.0805 0.0805
Echinococcus granulosus g-protein coupled receptor 0.0062 0.0335 0.0582
Loa Loa (eye worm) glutamate receptor 1 0.009 0.0514 0.0894
Trichomonas vaginalis Importin beta-1 subunit, putative 0.0025 0.0103 0.0565
Trichomonas vaginalis myo inositol monophosphatase, putative 0.0037 0.0181 0.1013
Trypanosoma cruzi mitochondrial DNA polymerase beta-PAK, putative 0.0039 0.0195 0.1142
Echinococcus granulosus nmda type glutamate receptor 0.0686 0.4253 0.7395
Brugia malayi neuropeptide F receptor 0.0062 0.0335 0.0871
Mycobacterium tuberculosis holo-[acyl-carrier protein] synthase AcpS (holo-ACP synthase) (CoA:APO-[ACP]pantetheinephosphotransferase) (CoA:APO-[acyl-carrie 0.0025 0.0102 0.0699
Echinococcus granulosus chromobox protein 1 0.0084 0.0475 0.0827
Entamoeba histolytica hypothetical protein 0.0014 0.0034 0.0399
Echinococcus granulosus g protein linked acetylcholine receptor gar 2a 0.0062 0.0335 0.0582
Echinococcus granulosus g protein coupled receptor 0.0062 0.0335 0.0582
Plasmodium falciparum metacaspase-like protein 0.0021 0.0082 0.1909
Mycobacterium tuberculosis Probable thymidylate synthase ThyA (ts) (TSASE) 0.0047 0.0244 0.172
Onchocerca volvulus Chorion peroxidase homolog 0.0029 0.013 0.0338
Loa Loa (eye worm) hypothetical protein 0.0029 0.013 0.0226
Loa Loa (eye worm) GTP-binding nuclear protein RAN/TC4 0.0022 0.0088 0.0154
Schistosoma mansoni hypothetical protein 0.0045 0.0227 0.0394
Echinococcus granulosus caspase 2 0.0071 0.0394 0.0685
Echinococcus granulosus rhodopsin orphan GPCR 0.0062 0.0335 0.0582
Echinococcus granulosus tyrosyl DNA phosphodiesterase 1 0.0069 0.0383 0.0666
Brugia malayi RNA recognition motif domain containing protein 0.0069 0.0382 0.0994
Echinococcus granulosus histone deacetylase 3 0.0029 0.0131 0.0228
Trichomonas vaginalis conserved hypothetical protein 0.0014 0.0034 0.0171
Trypanosoma cruzi DNA polymerase eta, putative 0.0038 0.0186 0.1091
Plasmodium vivax acyl-CoA synthetase, putative 0.0019 0.0065 0.1523
Trypanosoma cruzi DNA polymerase beta thumb, putative 0.0039 0.0195 0.1142
Mycobacterium ulcerans fatty-acid-CoA ligase 0.0019 0.0065 0.0436
Leishmania major importin beta-1 subunit, putative 0.0025 0.0103 0.0603
Brugia malayi Nuclear hormone receptor family member nhr-25 0.0009 0.0001 0.0003
Onchocerca volvulus Bile acid receptor homolog 0.0009 0.0001 0.0003
Schistosoma mansoni peptide (FMRFamide/neurokinin-3)-like receptor 0.0062 0.0335 0.0582
Loa Loa (eye worm) hypothetical protein 0.0062 0.0335 0.0582
Brugia malayi Dopamine receptor protein 1 0.0062 0.0335 0.0871
Onchocerca volvulus 0.0062 0.0335 0.0871
Loa Loa (eye worm) hypothetical protein 0.0062 0.0335 0.0582
Echinococcus granulosus arachidonate 5 lipoxygenase 0.0167 0.0998 0.1736
Trichomonas vaginalis Clan CD, family C14, metacaspase-like cysteine peptidase 0.0021 0.0082 0.0444
Trichomonas vaginalis conserved hypothetical protein 0.0014 0.0034 0.0171
Giardia lamblia DINP protein human, muc B family 0.0023 0.0094 0.371
Plasmodium falciparum histone deacetylase 1 0.0029 0.0131 0.3072
Schistosoma mansoni histone deacetylase 0.0029 0.0131 0.0228
Schistosoma mansoni amine GPCR 0.0062 0.0335 0.0582
Echinococcus multilocularis allatostatin A receptor 0.0062 0.0335 0.0335
Echinococcus granulosus growth hormone secretagogue receptor type 1 0.0062 0.0335 0.0582
Loa Loa (eye worm) animal heme peroxidase 0.0029 0.013 0.0226
Schistosoma mansoni mixed-lineage leukemia protein mll 0.001 0.001 0.0017
Mycobacterium ulcerans aldehyde dehydrogenase 0.0079 0.0445 0.316
Loa Loa (eye worm) hypothetical protein 0.0062 0.0335 0.0582
Loa Loa (eye worm) inositol-1 0.0037 0.0181 0.0314
Echinococcus granulosus allatostatin A receptor 0.0062 0.0335 0.0582
Trypanosoma cruzi DNA polymerase beta thumb, putative 0.0039 0.0195 0.1142
Echinococcus multilocularis serotonin receptor 0.0925 0.5751 0.5751
Plasmodium vivax hypothetical protein, conserved 0.0014 0.0034 0.0794
Loa Loa (eye worm) hypothetical protein 0.0062 0.0335 0.0582
Echinococcus multilocularis inositol polyphosphate 5 phosphatase OCRL 1 0.001 0.0008 0.0008
Onchocerca volvulus 0.0046 0.0238 0.062
Schistosoma mansoni transcription factor LCR-F1 0.0043 0.022 0.0383
Trichomonas vaginalis conserved hypothetical protein 0.0021 0.0082 0.0444
Echinococcus multilocularis metabotropic glutamate receptor 2 0.0046 0.0238 0.0238
Echinococcus multilocularis g protein linked acetylcholine receptor gar 2a 0.0062 0.0335 0.0335
Loa Loa (eye worm) CMGC/MAPK/ERK1 protein kinase 0.0015 0.004 0.007
Loa Loa (eye worm) hypothetical protein 0.0062 0.0335 0.0582
Schistosoma mansoni biogenic amine (dopamine) receptor 0.0062 0.0335 0.0582
Brugia malayi Serotonin receptor 0.0062 0.0335 0.0871
Loa Loa (eye worm) doublecortin family protein 0.0028 0.0123 0.0214
Schistosoma mansoni carbon catabolite repressor protein 0.001 0.0008 0.0013
Mycobacterium tuberculosis Probable bacterioferritin BfrA 0.001 0.0012 0.0055
Loa Loa (eye worm) hypothetical protein 0.001 0.0008 0.0013
Loa Loa (eye worm) hypothetical protein 0.0009 0.0001 0.0002
Trichomonas vaginalis conserved hypothetical protein 0.0019 0.0066 0.0354
Onchocerca volvulus GPI ethanolamine phosphate transferase 1 homolog 0.0009 0.0004 0.0011
Trypanosoma cruzi hypothetical protein, conserved 0.0016 0.0048 0.028
Echinococcus multilocularis mitogen activated protein kinase 3 0.0015 0.004 0.004
Onchocerca volvulus 0.0062 0.0335 0.0871
Entamoeba histolytica myo-inositol monophosphatase, putative 0.0037 0.0181 0.2634
Echinococcus granulosus RNA directed DNA polymerase 0.0012 0.0024 0.0041
Echinococcus granulosus g protein coupled receptor 0.0062 0.0335 0.0582
Loa Loa (eye worm) hypothetical protein 0.005 0.026 0.0452
Loa Loa (eye worm) hypothetical protein 0.0016 0.0048 0.0083
Brugia malayi steroid hormone receptor 0.0009 0.0001 0.0003
Echinococcus granulosus rhodopsin orphan GPCR 0.0062 0.0335 0.0582
Echinococcus multilocularis Basic leucine zipper (bZIP) transcription 0.0043 0.022 0.022
Plasmodium falciparum ATP-dependent 6-phosphofructokinase 0.0031 0.0141 0.3304
Entamoeba histolytica chromodomain-helicase-DNA-binding protein, putative 0.0014 0.0034 0.0399
Mycobacterium tuberculosis Probable esterase LipL 0.0016 0.0048 0.0312
Loa Loa (eye worm) TAR-binding protein 0.0069 0.0382 0.0664
Plasmodium falciparum holo-[acyl-carrier-protein] synthase, putative 0.0025 0.0102 0.2381
Mycobacterium ulcerans cytochrome P450 185A4 Cyp185A4 0.0013 0.0029 0.0176
Plasmodium falciparum carbon catabolite repressor protein 4, putative 0.001 0.0008 0.0181
Loa Loa (eye worm) helicase 0.0014 0.0034 0.0059
Echinococcus granulosus GPCR family 2 0.0021 0.0077 0.0134
Chlamydia trachomatis ATP-dependent Clp protease proteolytic subunit 0.0077 0.0428 0.2715
Schistosoma mansoni retinoid-x-receptor (RXR) 0.0009 0.0001 0.0002
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0062 0.0335 0.0582
Echinococcus multilocularis tyrosine kinase 0.0046 0.0238 0.0238
Schistosoma mansoni ferritin 0.001 0.0012 0.0021
Echinococcus granulosus neuropeptides capa receptor 0.0062 0.0335 0.0582
Brugia malayi Valyl-tRNA synthetase 0.0014 0.0034 0.0088
Trichomonas vaginalis type II inositol 5-phosphatase, putative 0.001 0.0008 0.002
Toxoplasma gondii histone deacetylase HDAC2 0.0029 0.0131 0.2949
Loa Loa (eye worm) intermediate filament tail domain-containing protein 0.0017 0.0055 0.0096
Toxoplasma gondii ABC1 family protein 0.0016 0.0048 0.1072
Schistosoma mansoni protein kinase 0.0046 0.0238 0.0414
Loa Loa (eye worm) CHromoDomain protein family member 0.0017 0.0051 0.0089
Loa Loa (eye worm) histone deacetylase 3 0.0029 0.0131 0.0228
Brugia malayi histone deacetylase 3 (HD3) 0.0029 0.0131 0.0342
Trypanosoma cruzi histone deacetylase 1, putative 0.0029 0.0131 0.0771
Trichomonas vaginalis CMGC family protein kinase 0.0015 0.004 0.0206
Loa Loa (eye worm) hypothetical protein 0.0062 0.0335 0.0582
Echinococcus granulosus lipoxygenase domain containing protein 0.0028 0.0123 0.0214
Trichomonas vaginalis ocrl type II inositol 5-phosphatase, putative 0.001 0.0008 0.002
Trypanosoma cruzi myo-inositol-1(or 4)-monophosphatase 1, putative 0.0037 0.0181 0.1061
Brugia malayi Nuclear hormone receptor family member nhr-49 0.0009 0.0001 0.0003
Brugia malayi Receptor family ligand binding region containing protein 0.0046 0.0238 0.062
Schistosoma mansoni neuropeptide receptor 0.0062 0.0335 0.0582
Trichomonas vaginalis sphingomyelinase C 2 precursor, putative 0.001 0.0008 0.002
Echinococcus multilocularis Nuclear hormone receptor family member nhr 41 0.0009 0.0001 0.0001
Echinococcus multilocularis neuropeptide receptor A26 0.0062 0.0335 0.0335
Trichomonas vaginalis D-aminoacylase, putative 0.0016 0.0048 0.025
Trypanosoma brucei monoglyceride lipase, putative 0.0019 0.0066 0.0386
Trichomonas vaginalis conserved hypothetical protein 0.0033 0.0157 0.0877
Mycobacterium leprae PROBABLE FATTY-ACID-CoA LIGASE FADD2 (FATTY-ACID-CoA SYNTHETASE) (FATTY-ACID-CoA SYNTHASE) 0.0025 0.0105 0.1426
Mycobacterium tuberculosis Probable esterase/lipase LipP 0.0016 0.0048 0.0312
Loa Loa (eye worm) hypothetical protein 0.0046 0.0238 0.0414
Trichomonas vaginalis penicillin-binding protein, putative 0.0016 0.0048 0.025
Leishmania major mitogen activated protein kinase 4, putative;with=GeneDB:LmxM19.1440 0.0015 0.004 0.0235
Onchocerca volvulus 0.0015 0.004 0.0103
Echinococcus multilocularis expressed protein 0.001 0.0012 0.0012
Echinococcus multilocularis snurportin 1 0.0326 0.199 0.199
Schistosoma mansoni Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) 0.0101 0.058 0.1009
Brugia malayi hypothetical protein 0.0205 0.1232 0.3204
Leishmania major inositol phosphosphingolipid phospholipase C-Like 0.001 0.0008 0.0045
Mycobacterium ulcerans bacterioferritin BfrB 0.001 0.0012 0.0055
Plasmodium falciparum AP endonuclease (DNA-[apurinic or apyrimidinic site] lyase), putative 0.0048 0.0246 0.5745
Schistosoma mansoni biogenic amine receptor 0.0062 0.0335 0.0582
Loa Loa (eye worm) cytochrome P450 family protein 0.0013 0.0029 0.005
Onchocerca volvulus 0.0062 0.0335 0.0871
Schistosoma mansoni ran 0.0022 0.0088 0.0154
Echinococcus granulosus neuropeptides capa receptor 0.0062 0.0335 0.0582
Schistosoma mansoni glutamate receptor kainate 0.009 0.0514 0.0894
Trypanosoma cruzi mitochondrial protein 99, putative 0.001 0.0008 0.0045
Brugia malayi Blistered cuticle protein 3 0.0029 0.013 0.0338
Loa Loa (eye worm) hypothetical protein 0.0062 0.0335 0.0582
Onchocerca volvulus 0.0029 0.013 0.0338
Echinococcus multilocularis thyroid hormone receptor alpha 0.0009 0.0001 0.0001
Echinococcus granulosus neuropeptide Y receptor 0.0062 0.0335 0.0582
Toxoplasma gondii CMGC kinase, MAPK family (ERK) MAPK-1 0.0015 0.004 0.09
Mycobacterium tuberculosis Conserved protein 0.0016 0.0048 0.0312
Echinococcus multilocularis caspase 2 0.0071 0.0394 0.0394
Trichomonas vaginalis conserved hypothetical protein 0.0014 0.0034 0.0171
Schistosoma mansoni bifunctional dihydrofolate reductase-thymidylate synthase 0.0047 0.0244 0.0425
Mycobacterium ulcerans DNA polymerase IV 0.0023 0.0094 0.0642
Schistosoma mansoni tar DNA-binding protein 0.0069 0.0382 0.0664
Loa Loa (eye worm) hypothetical protein 0.0029 0.013 0.0226
Echinococcus granulosus peptide allatostatin:somatostatin 0.0062 0.0335 0.0582
Schistosoma mansoni RAR-like nuclear receptor 0.0009 0.0001 0.0002
Onchocerca volvulus Neuropeptide F receptor homolog 0.0062 0.0335 0.0871
Brugia malayi hypothetical protein 0.0062 0.0335 0.0871
Schistosoma mansoni nuclear hormone receptor 0.0009 0.0001 0.0002
Schistosoma mansoni nuclear receptor 2DBD-gamma 0.0009 0.0001 0.0002
Plasmodium vivax histone deacetylase 1, putative 0.0029 0.0131 0.3072
Echinococcus multilocularis Ataxin 2, N terminal,domain containing protein 0.0024 0.0096 0.0096
Loa Loa (eye worm) hypothetical protein 0.0029 0.013 0.0226
Trypanosoma cruzi myo-inositol-1(or 4)-monophosphatase 1, putative 0.0037 0.0181 0.1061
Mycobacterium ulcerans hypothetical protein 0.0016 0.0048 0.0312
Schistosoma mansoni neuropeptide receptor 0.0062 0.0335 0.0582
Echinococcus multilocularis GTP binding nuclear protein Ran 0.0022 0.0088 0.0088
Onchocerca volvulus 0.0621 0.3843 1
Brugia malayi hypothetical protein 0.0062 0.0335 0.0871
Brugia malayi F/Y-rich N-terminus family protein 0.0013 0.0027 0.0071
Brugia malayi Nuclear hormone receptor family member nhr-31 0.0009 0.0001 0.0003
Echinococcus granulosus caspase 8 0.0021 0.0082 0.0142
Echinococcus granulosus rhodopsin orphan GPCR 0.0062 0.0335 0.0582
Schistosoma mansoni hypothetical protein 0.0326 0.199 0.3461
Loa Loa (eye worm) hypothetical protein 0.0047 0.0243 0.0423
Loa Loa (eye worm) hypothetical protein 0.0062 0.0335 0.0582
Mycobacterium tuberculosis Probable aldehyde dehydrogenase 0.0079 0.0445 0.316
Echinococcus multilocularis zinc finger protein 0.001 0.0009 0.0009
Loa Loa (eye worm) hypothetical protein 0.0062 0.0335 0.0582
Trichomonas vaginalis histone deacetylase 1, 2 ,3, putative 0.0029 0.0131 0.073
Trypanosoma cruzi mitochondrial DNA polymerase beta-PAK, putative 0.0132 0.0779 0.4571
Toxoplasma gondii HEAT repeat-containing protein 0.003 0.0139 0.3119
Toxoplasma gondii endonuclease/exonuclease/phosphatase family protein 0.001 0.0008 0.0174
Loa Loa (eye worm) metabotropic GABA-B receptor subtype 2 0.0046 0.0238 0.0414
Schistosoma mansoni serine/threonine protein kinase 0.0017 0.0055 0.0095
Schistosoma mansoni metabotropic glutamate receptor 0.0046 0.0238 0.0414
Loa Loa (eye worm) hypothetical protein 0.0062 0.0335 0.0582
Onchocerca volvulus Atrial natriuretic peptide receptor 3 homolog 0.0046 0.0238 0.062
Entamoeba histolytica chromodomain-helicase-DNA-binding protein, putative 0.0014 0.0034 0.0399
Leishmania major mitochondrial DNA polymerase beta 0.028 0.1704 1
Onchocerca volvulus 0.0028 0.0123 0.0321
Trypanosoma cruzi apurinic/apyrimidinic endonuclease, putative 0.001 0.0008 0.0045
Toxoplasma gondii ImpB/MucB/SamB family protein 0.0038 0.0186 0.4175
Brugia malayi hypothetical protein 0.0043 0.022 0.0573
Trichomonas vaginalis carbon catabolite repressor protein, putative 0.001 0.0008 0.002
Loa Loa (eye worm) hypothetical protein 0.0029 0.013 0.0226
Schistosoma mansoni retinoic acid receptor RXR 0.0009 0.0001 0.0002
Mycobacterium tuberculosis Probable conserved lipoprotein 0.0016 0.0048 0.0312
Loa Loa (eye worm) hypothetical protein 0.0062 0.0335 0.0582
Echinococcus multilocularis G-protein coupled receptor, putative 0.0062 0.0335 0.0335
Trichomonas vaginalis chromodomain-helicase-DNA-binding protein, putative 0.0022 0.0083 0.0454
Loa Loa (eye worm) hypothetical protein 0.0046 0.0238 0.0414
Loa Loa (eye worm) 5-hydroxytryptamine 2C receptor 0.0062 0.0335 0.0582
Echinococcus granulosus hypothetical protein 0.0062 0.0335 0.0582
Echinococcus multilocularis g-protein coupled receptor 0.0062 0.0335 0.0335
Loa Loa (eye worm) beta-LACTamase domain containing family member 0.0016 0.0048 0.0083
Mycobacterium ulcerans fusion of enoyl-CoA hydratase, EchA21 and lipase, LipE 0.0016 0.0048 0.0312
Echinococcus granulosus inositol monophosphatase 1 0.0037 0.0181 0.0314
Plasmodium vivax ATP-dependent Clp protease proteolytic subunit, putative 0.0026 0.0113 0.2642
Loa Loa (eye worm) RGC/RGC protein kinase 0.0046 0.0238 0.0414
Trypanosoma cruzi hypothetical protein, conserved 0.0016 0.0048 0.028
Trichomonas vaginalis myo inositol monophosphatase, putative 0.0037 0.0181 0.1013
Brugia malayi ImpB/MucB/SamB family protein 0.0023 0.0094 0.0244
Brugia malayi Animal haem peroxidase family protein 0.0029 0.013 0.0338
Loa Loa (eye worm) hypothetical protein 0.0015 0.0044 0.0076
Schistosoma mansoni glutamate receptor AMPA 0.009 0.0514 0.0894
Trichomonas vaginalis Clan CD, family C14, metacaspase-like cysteine peptidase 0.0021 0.0082 0.0444
Brugia malayi MH2 domain containing protein 0.0053 0.028 0.0728
Loa Loa (eye worm) hypothetical protein 0.0205 0.1232 0.2142
Echinococcus granulosus Polycystic kidney disease protein 0.0028 0.0123 0.0214
Schistosoma mansoni amine GPCR 0.0062 0.0335 0.0582
Mycobacterium ulcerans lysophospholipase 0.0019 0.0066 0.0441
Schistosoma mansoni dihydrofolate reductase 0.0019 0.0069 0.0119
Echinococcus multilocularis tm gpcr rhodopsin gpcr rhodopsin superfamily 0.0062 0.0335 0.0335
Schistosoma mansoni hypothetical protein 0.0062 0.0335 0.0582
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0062 0.0335 0.0582
Loa Loa (eye worm) hypothetical protein 0.0029 0.013 0.0226
Brugia malayi CCR4 0.001 0.0008 0.002
Schistosoma mansoni inhibitor of apoptosis (iap) domain family member 0.0015 0.004 0.0069
Trichomonas vaginalis phosphofructokinase, putative 0.0031 0.0141 0.0787
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0062 0.0335 0.0582
Trypanosoma brucei unspecified product 0.0016 0.0048 0.0284
Echinococcus multilocularis lipoxygenase domain containing protein 0.0028 0.0123 0.0123
Toxoplasma gondii bifunctional dihydrofolate reductase-thymidylate synthase 0.0067 0.0365 0.8204
Trichomonas vaginalis histone deacetylase, putative 0.0029 0.0131 0.073
Echinococcus multilocularis biogenic amine (5HT) receptor 0.0062 0.0335 0.0335
Leishmania major cytochrome p450-like protein 0.0013 0.0029 0.0168
Schistosoma mansoni neuropeptide F-like receptor 0.0062 0.0335 0.0582
Mycobacterium tuberculosis Probable lipase LipE 0.0016 0.0048 0.0312
Mycobacterium leprae PROBABLE THYMIDYLATE SYNTHASE THYA (TS) (TSASE) 0.0047 0.0244 0.3563
Trichomonas vaginalis Clan SC, family S33, methylesterase-like serine peptidase 0.0019 0.0066 0.0354
Echinococcus granulosus caspase 3 apoptosis cysteine peptidase 0.0021 0.0082 0.0142
Onchocerca volvulus Putative neutral sphingomyelinase 0.001 0.0008 0.002
Toxoplasma gondii phosphofructokinase domain-containing protein 0.0031 0.0141 0.3172
Echinococcus multilocularis glutamate (NMDA) receptor subunit 0.0299 0.1821 0.1821
Trichomonas vaginalis Clan CD, family C14, metacaspase-like cysteine peptidase 0.0021 0.0082 0.0444
Trypanosoma cruzi DNA polymerase kappa, putative 0.0023 0.0094 0.055
Brugia malayi Tyrosyl-DNA phosphodiesterase family protein 0.0069 0.0383 0.0997
Echinococcus granulosus rhodopsin orphan GPCR 0.0062 0.0335 0.0582
Trypanosoma cruzi DNA polymerase eta, putative 0.0054 0.0287 0.1683
Trichomonas vaginalis Clan SC, family S33, methylesterase-like serine peptidase 0.0019 0.0066 0.0354
Trypanosoma brucei hypothetical protein, conserved 0.0016 0.0048 0.028
Echinococcus multilocularis cadherin EGF LAG seven pass G type receptor 0.0021 0.0077 0.0077
Plasmodium falciparum LCCL domain-containing protein 0.0028 0.0123 0.2881
Loa Loa (eye worm) hypothetical protein 0.0062 0.0335 0.0582
Brugia malayi putative neuropeptide receptor 0.0062 0.0335 0.0871
Brugia malayi MAP kinase sur-1 0.0015 0.004 0.0104
Toxoplasma gondii endonuclease/exonuclease/phosphatase family protein 0.001 0.0008 0.0174
Entamoeba histolytica acyl-coA synthetase, putative 0.0025 0.0105 0.1479
Brugia malayi Tachykinin-like peptides receptor 99D 0.0062 0.0335 0.0871
Loa Loa (eye worm) GTP-binding regulatory protein Gs alpha-S chain 0.0101 0.058 0.1009
Trichomonas vaginalis conserved hypothetical protein 0.0021 0.0082 0.0444
Trichomonas vaginalis histone deacetylase, putative 0.0029 0.0131 0.073
Echinococcus granulosus Nuclear hormone receptor family member nhr 41 0.0009 0.0001 0.0002
Schistosoma mansoni lamin 0.0017 0.0055 0.0096
Entamoeba histolytica hydrolase, alpha/beta fold family domain containing protein 0.0019 0.0066 0.0884
Onchocerca volvulus 0.0017 0.0055 0.0144
Mycobacterium tuberculosis Probable lipase LipD 0.0016 0.0048 0.0312
Brugia malayi G-protein-linked acetylcholine receptor protein 2, putative 0.0062 0.0335 0.0871
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0062 0.0335 0.0582
Echinococcus multilocularis caspase 0.0021 0.0082 0.0082
Mycobacterium tuberculosis Conserved protein 0.0016 0.0048 0.0312
Trypanosoma cruzi dihydrofolate reductase-thymidylate synthase 0.0067 0.0365 0.2145
Mycobacterium ulcerans 6-phosphofructokinase 0.0114 0.0665 0.473
Echinococcus granulosus Basic leucine zipper bZIP transcription 0.0043 0.022 0.0383
Mycobacterium ulcerans hypothetical protein 0.0147 0.0873 0.622
Brugia malayi Nuclear hormone receptor family member nhr-1 0.0009 0.0001 0.0003
Toxoplasma gondii 'chromo' (CHRromatin Organization MOdifier) domain-containing protein 0.0014 0.0034 0.0762
Schistosoma mansoni hypothetical protein 0.0009 0.0002 0.0003
Trichomonas vaginalis conserved hypothetical protein 0.0021 0.0082 0.0444
Brugia malayi Inhibitor of Apoptosis domain containing protein 0.0015 0.004 0.0103
Echinococcus granulosus alpha 1A adrenergic receptor 0.0062 0.0335 0.0582
Echinococcus granulosus dihydrofolate reductase 0.0019 0.0069 0.0119
Echinococcus granulosus muscleblind protein 0.005 0.0263 0.0458
Brugia malayi Endonuclease/Exonuclease/phosphatase family protein 0.001 0.0008 0.002
Trichomonas vaginalis ran, putative 0.0022 0.0088 0.0483
Schistosoma mansoni chromobox protein-related (chromobox 1) (heterochromatin 1) 0.0014 0.0034 0.0059
Mycobacterium tuberculosis Probable fatty-acid-CoA ligase FadD35 (fatty-acid-CoA synthetase) (fatty-acid-CoA synthase) 0.0018 0.0059 0.039
Schistosoma mansoni serine/threonine protein kinase 0.0017 0.0055 0.0095
Trichomonas vaginalis Clan CD, family C14, metacaspase-like cysteine peptidase 0.0021 0.0082 0.0444
Schistosoma mansoni adenoreceptor 0.0062 0.0335 0.0582
Schistosoma mansoni tyrosyl-DNA phosphodiesterase 0.0069 0.0383 0.0666
Schistosoma mansoni chromobox protein 0.0014 0.0034 0.0059
Giardia lamblia Kinase, CMGC MAPK 0.0015 0.004 0.1487
Trichomonas vaginalis histone deacetylase, putative 0.0029 0.0131 0.073
Leishmania major dihydrofolate reductase-thymidylate synthase 0.0067 0.0365 0.2145
Echinococcus multilocularis tm gpcr rhodopsin gpcr rhodopsin superfamily 0.0062 0.0335 0.0335
Entamoeba histolytica pyrophosphate-dependent phosphofructokinase 0.0031 0.0141 0.2033
Brugia malayi Nuclear hormone receptor-like 1 0.0009 0.0001 0.0003
Brugia malayi TAR-binding protein 0.0069 0.0382 0.0994
Echinococcus multilocularis chromodomain helicase DNA binding protein 4 0.0017 0.0051 0.0051
Echinococcus multilocularis deoxyribonuclease 1 2 0.001 0.0008 0.0008
Wolbachia endosymbiont of Brugia malayi 4'-phosphopantetheinyl transferase 0.0025 0.0102 0.2165
Chlamydia trachomatis holo [acyl-carrier protein] synthase 0.0025 0.0102 0.0275
Trichomonas vaginalis DNA polymerase IV / kappa, putative 0.0023 0.0094 0.0514
Trypanosoma brucei DNA polymerase IV, putative 0.0023 0.0094 0.055
Loa Loa (eye worm) hypothetical protein 0.0062 0.0335 0.0582
Trypanosoma brucei DNA polymerase kappa, putative 0.0023 0.0094 0.055
Loa Loa (eye worm) hypothetical protein 0.001 0.0008 0.0013
Trichomonas vaginalis phosphofructokinase, putative 0.0114 0.0665 0.3789
Plasmodium vivax endonuclease/exonuclease/phosphatase domain containing protein 0.001 0.0008 0.0181
Brugia malayi latrophilin 2 splice variant baaae 0.0045 0.0227 0.059
Mycobacterium leprae PROBABLE 6-PHOSPHOFRUCTOKINASE PFKA (PHOSPHOHEXOKINASE) (PHOSPHOFRUCTOKINASE) 0.0114 0.0665 1
Trichomonas vaginalis DNA polymerase eta, putative 0.0023 0.0094 0.0514
Leishmania major 4-coumarate:coa ligase-like protein 0.0025 0.0105 0.0616
Loa Loa (eye worm) hypothetical protein 0.0009 0.0001 0.0002
Brugia malayi hypothetical protein 0.0014 0.0034 0.0088
Onchocerca volvulus 0.005 0.026 0.0676
Leishmania major endonuclease/exonuclease protein-like protein 0.001 0.0008 0.0045
Onchocerca volvulus 0.0017 0.0055 0.0144
Trichomonas vaginalis chromobox protein, putative 0.0051 0.0266 0.1502
Loa Loa (eye worm) hypothetical protein 0.0062 0.0335 0.0582
Trichomonas vaginalis Phospholipase C precursor, putative 0.001 0.0008 0.002
Brugia malayi Endonuclease/Exonuclease/phosphatase family protein 0.001 0.0008 0.002
Trichomonas vaginalis D-aminoacylase, putative 0.0016 0.0048 0.025
Trichomonas vaginalis skeletal muscle/kidney enriched inositol 5-phosphatase, putative 0.001 0.0008 0.002
Echinococcus multilocularis rhodopsin orphan GPCR 0.0062 0.0335 0.0335
Echinococcus granulosus aldehyde dehydrogenase mitochondrial 0.0079 0.0445 0.0775
Echinococcus multilocularis rhodopsin orphan GPCR 0.0062 0.0335 0.0335
Plasmodium vivax GTP-binding nuclear protein RAN/TC4, putative 0.0022 0.0088 0.2067
Onchocerca volvulus 0.0042 0.0209 0.0545
Mycobacterium tuberculosis Probable fatty-acid-CoA ligase FadD7 (fatty-acid-CoA synthetase) (fatty-acid-CoA synthase) 0.0018 0.0059 0.039
Trypanosoma cruzi metacaspase 5, putative 0.0021 0.0082 0.0479
Echinococcus granulosus fetal alzheimer antigen falz 0.0011 0.0017 0.0029
Schistosoma mansoni ferritin 0.001 0.0012 0.0021
Echinococcus granulosus Glutamate receptor ionotropic kainate 2 0.0137 0.0805 0.14
Entamoeba histolytica phosphofructokinase, putative 0.0114 0.0665 1
Plasmodium falciparum conserved Plasmodium protein, unknown function 0.0014 0.0034 0.0794
Brugia malayi Calcitonin receptor-like protein seb-1 0.0065 0.0356 0.0927
Loa Loa (eye worm) hypothetical protein 0.0009 0.0004 0.0007
Plasmodium vivax exodeoxyribonuclease III, putative 0.001 0.0008 0.0181
Echinococcus granulosus serotonin receptor 0.0062 0.0335 0.0582
Plasmodium falciparum endonuclease/exonuclease/phosphatase family protein, putative 0.001 0.0008 0.0181
Echinococcus multilocularis peroxidasin 0.0029 0.013 0.013
Trichomonas vaginalis ap endonuclease, putative 0.0048 0.0246 0.1386
Mycobacterium tuberculosis Probable hydrolase 0.0016 0.0048 0.0312
Entamoeba histolytica phosphofructokinase, putative 0.0114 0.0665 1
Mycobacterium ulcerans extragenic suppressor protein SuhB 0.0037 0.0181 0.1265
Leishmania major hypothetical protein, conserved 0.0016 0.0048 0.028
Brugia malayi AKH receptor 0.0062 0.0335 0.0871
Leishmania major pantothenate kinase subunit, putative 0.0011 0.0014 0.0083
Echinococcus granulosus 7tm_1 domain containing protein 0.0062 0.0335 0.0582
Echinococcus granulosus cpg binding protein 0.0037 0.0182 0.0317
Echinococcus granulosus somatostatin receptor 0.0062 0.0335 0.0582
Mycobacterium tuberculosis Probable 6-phosphofructokinase PfkA (phosphohexokinase) (phosphofructokinase) 0.0114 0.0665 0.473
Schistosoma mansoni inhibitor of apoptosis protein 0.0015 0.004 0.0069
Echinococcus granulosus bromodomain adjacent to zinc finger domain 0.0014 0.0038 0.0066
Trichomonas vaginalis hypothetical protein 0.0014 0.0034 0.0171
Echinococcus multilocularis transcription factor Dp 1 0.004 0.02 0.02
Echinococcus multilocularis ferritin 0.001 0.0012 0.0012
Onchocerca volvulus Dual oxidase homolog 0.0029 0.013 0.0338
Echinococcus granulosus chromobox protein 1 0.0084 0.0475 0.0827
Loa Loa (eye worm) endonuclease/Exonuclease/phosphatase 0.001 0.0008 0.0013
Trypanosoma cruzi apurinic/apyrimidinic endonuclease, putative 0.0048 0.0246 0.1442
Plasmodium vivax importin-beta 2, putative 0.003 0.0139 0.3249
Echinococcus granulosus histone lysine N methyltransferase MLL3 0.0012 0.0023 0.004
Plasmodium vivax ATP-dependent Clp protease proteolytic subunit, putative 0.0077 0.0428 1
Trichomonas vaginalis conserved hypothetical protein 0.0014 0.0034 0.0171
Trypanosoma brucei metacaspase 5, putative 0.0021 0.0082 0.0479
Schistosoma mansoni rab geranylgeranyl transferase alpha subunit 0.0023 0.0094 0.0163
Trypanosoma cruzi GTP-binding nuclear protein rtb2, putative 0.0022 0.0088 0.0519
Toxoplasma gondii endonuclease/exonuclease/phosphatase family protein 0.001 0.0008 0.0174
Echinococcus granulosus mixed lineage leukemia protein mll 0.001 0.001 0.0017
Schistosoma mansoni synaptojanin 0.001 0.0008 0.0013
Trypanosoma cruzi Inositol phosphosphingolipids phospholipase C 0.001 0.0008 0.0045
Brugia malayi ORL1-like opioid receptor 0.0062 0.0335 0.0871
Echinococcus multilocularis glutamate receptor, ionotrophic, AMPA 3 0.0137 0.0805 0.0805
Brugia malayi exodeoxyribonuclease III family protein 0.0048 0.0246 0.0639
Echinococcus multilocularis neuropeptides capa receptor 0.0062 0.0335 0.0335
Brugia malayi photoreceptor-specific nuclear receptor 0.0009 0.0001 0.0003
Brugia malayi hypothetical protein 0.0621 0.3843 1
Echinococcus multilocularis neuropeptide Y receptor 0.0062 0.0335 0.0335
Echinococcus multilocularis bromodomain adjacent to zinc finger domain 0.0014 0.0038 0.0038
Echinococcus granulosus DNA apurinic or apyrimidinic site lyase 0.0048 0.0246 0.0427
Mycobacterium tuberculosis Dihydrofolate reductase DfrA (DHFR) (tetrahydrofolate dehydrogenase) 0.0019 0.0069 0.0461
Schistosoma mansoni muscarinic acetylcholine (GAR) receptor 0.0062 0.0335 0.0582
Echinococcus granulosus expressed protein 0.001 0.0012 0.0021
Trypanosoma cruzi mitochondrial DNA polymerase beta, putative 0.028 0.1704 1
Brugia malayi G-protein coupled receptor 0.0062 0.0335 0.0871
Echinococcus multilocularis Glutamate receptor, ionotropic kainate 2 0.0137 0.0805 0.0805
Brugia malayi GTP-binding regulatory protein Gs alpha-S chain, putative 0.0101 0.058 0.1509
Loa Loa (eye worm) hypothetical protein 0.0071 0.0394 0.0685
Trichomonas vaginalis conserved hypothetical protein 0.0014 0.0034 0.0171
Echinococcus multilocularis survival motor neuron protein 1 0.0205 0.1232 0.1232
Brugia malayi Hypothetical 52.5 kDa protein ZK945.1 in chromosome II, putative 0.0016 0.0048 0.0124
Entamoeba histolytica phosphofructokinase, putative 0.0114 0.0665 1
Plasmodium vivax endonuclease/exonuclease/phosphatase domain containing protein 0.001 0.0008 0.0181
Brugia malayi Serotonin receptor 0.0332 0.2029 0.528
Entamoeba histolytica exodeoxyribonuclease III, putative 0.0048 0.0246 0.3622
Schistosoma mansoni opsin-like receptor 0.0062 0.0335 0.0582
Schistosoma mansoni hypothetical protein 0.001 0.0008 0.0013
Onchocerca volvulus 0.0009 0.0002 0.0005
Brugia malayi Dopamine receptor protein 2 0.0062 0.0335 0.0871
Entamoeba histolytica hypothetical protein 0.0043 0.022 0.3233
Plasmodium falciparum esterase, putative 0.0019 0.0066 0.1539
Loa Loa (eye worm) hypothetical protein 0.0016 0.0048 0.0083
Plasmodium vivax SET domain protein, putative 0.0037 0.0178 0.4174
Trypanosoma cruzi tyrosyl-DNA Phosphodiesterase (Tdp1), putative 0.0069 0.0383 0.2248
Echinococcus granulosus diuretic hormone 44 receptor GPRdih2 0.0021 0.0077 0.0134
Brugia malayi hypothetical protein 0.0028 0.0123 0.0321
Brugia malayi beta-lactamase family protein 0.0016 0.0048 0.0124
Schistosoma mansoni opsin-like receptor 0.0062 0.0335 0.0582
Onchocerca volvulus 0.0014 0.0034 0.0088
Mycobacterium ulcerans dihydrofolate reductase DfrA 0.0019 0.0069 0.0461
Trichomonas vaginalis chromobox protein, putative 0.0084 0.0475 0.2704
Onchocerca volvulus 0.0047 0.0244 0.0636
Echinococcus granulosus glutamate receptor ionotrophic AMPA 3 0.0137 0.0805 0.14
Brugia malayi Endonuclease/Exonuclease/phosphatase family protein 0.001 0.0008 0.002
Loa Loa (eye worm) endonuclease/Exonuclease/phosphatase 0.001 0.0008 0.0013
Echinococcus granulosus tyrosine kinase 0.0046 0.0238 0.0414
Schistosoma mansoni tar DNA-binding protein 0.0069 0.0382 0.0664
Echinococcus multilocularis tm gpcr rhodopsin gpcr rhodopsin superfamily 0.0062 0.0335 0.0335
Schistosoma mansoni hypothetical protein 0.0021 0.0077 0.0134
Brugia malayi hypothetical protein 0.0062 0.0335 0.0871
Echinococcus granulosus rhodopsin orphan GPCR 0.0062 0.0335 0.0582
Onchocerca volvulus 0.0035 0.0165 0.043
Trichomonas vaginalis conserved hypothetical protein 0.0014 0.0034 0.0171
Loa Loa (eye worm) hypothetical protein 0.001 0.0008 0.0013
Trichomonas vaginalis ferritin, putative 0.001 0.0012 0.0044
Echinococcus multilocularis ATP dependent Clp protease proteolytic subunit 0.0077 0.0428 0.0428
Trichomonas vaginalis Clan SC, family S33, methylesterase-like serine peptidase 0.0019 0.0066 0.0354
Echinococcus granulosus metabotropic glutamate receptor 2 0.0046 0.0238 0.0414
Loa Loa (eye worm) hypothetical protein 0.0037 0.018 0.0312
Onchocerca volvulus Matrilysin homolog 0.0014 0.0033 0.0085
Loa Loa (eye worm) hypothetical protein 0.0028 0.0125 0.0217
Treponema pallidum diphosphate--fructose-6-phosphate 1-phosphotransferase 0.0114 0.0665 0.4717
Loa Loa (eye worm) hypothetical protein 0.0062 0.0335 0.0582
Loa Loa (eye worm) hypothetical protein 0.0046 0.0238 0.0414
Loa Loa (eye worm) metabotropic glutamate receptor 8 0.0046 0.0238 0.0414
Chlamydia trachomatis dihydrofolate reductase 0.0019 0.0069 0.0026
Brugia malayi Glutamate receptor 2 precursor 0.009 0.0514 0.1338
Onchocerca volvulus Dopamine\/Ecdysteroid receptor homolog 0.0062 0.0335 0.0871
Mycobacterium tuberculosis Probable fatty-acid-CoA ligase FadD3 (fatty-acid-CoA synthetase) (fatty-acid-CoA synthase) 0.0018 0.0059 0.039
Onchocerca volvulus 0.0062 0.0335 0.0871
Trypanosoma cruzi metacaspase, putative 0.0021 0.0082 0.0479
Mycobacterium leprae DIHYDROFOLATE REDUCTASE DFRA (DHFR) (TETRAHYDROFOLATE DEHYDROGENASE) 0.0019 0.0069 0.087
Echinococcus multilocularis Glutamate receptor, ionotropic kainate 3 0.0322 0.1967 0.1967
Schistosoma mansoni peroxidasin 0.0029 0.013 0.0226
Echinococcus multilocularis dna polymerase eta 0.0054 0.0287 0.0287
Loa Loa (eye worm) hypothetical protein 0.0019 0.0065 0.0113
Onchocerca volvulus 0.0009 0.0002 0.0005
Brugia malayi hypothetical protein 0.0062 0.0335 0.0871
Toxoplasma gondii endonuclease/exonuclease/phosphatase family protein 0.001 0.0008 0.0174
Loa Loa (eye worm) hypothetical protein 0.0019 0.0067 0.0116
Echinococcus multilocularis neuropeptide Y receptor 0.0062 0.0335 0.0335
Trichomonas vaginalis chromodomain helicase DNA binding protein, putative 0.0022 0.0083 0.0454
Echinococcus granulosus COUP TF:Svp nuclear hormone receptor 0.0009 0.0001 0.0002
Plasmodium falciparum lysophospholipase, putative 0.0019 0.0066 0.1539
Echinococcus multilocularis FTZ F1 alpha 0.0009 0.0001 0.0001
Loa Loa (eye worm) hypothetical protein 0.0012 0.0024 0.0041
Echinococcus granulosus ATP dependent Clp protease proteolytic subunit 0.0077 0.0428 0.0744
Brugia malayi calcium-independent alpha-latrotoxin receptor 2, putative 0.0021 0.0077 0.02
Loa Loa (eye worm) hypothetical protein 0.0025 0.0105 0.0182
Schistosoma mansoni hypothetical protein 0.0024 0.0096 0.0167
Echinococcus multilocularis Polycystic kidney disease protein 0.0028 0.0123 0.0123
Brugia malayi Type III restriction enzyme, res subunit family protein 0.0014 0.0034 0.0088
Brugia malayi Steroid receptor seven-up type 2 0.0009 0.0001 0.0003
Mycobacterium tuberculosis Conserved hypothetical protein 0.0147 0.0873 0.622
Brugia malayi Nuclear hormone receptor family member nhr-19 0.0009 0.0001 0.0003
Loa Loa (eye worm) hypothetical protein 0.0025 0.0105 0.0182
Schistosoma mansoni inositol monophosphatase 0.0037 0.0181 0.0314
Schistosoma mansoni photoreceptor-specific nuclear receptor related 0.0009 0.0001 0.0002
Trypanosoma brucei DNA polymerase beta thumb, putative 0.0039 0.0195 0.1142
Echinococcus granulosus nuclear receptor 2DBD gamma 0.0009 0.0001 0.0002
Loa Loa (eye worm) nuclear hormone receptor family member nhr-14 0.0009 0.0001 0.0002
Loa Loa (eye worm) hypothetical protein 0.0029 0.013 0.0226
Leishmania major myo-inositol-1(or 4)-monophosphatase 1, putative 0.0037 0.0181 0.1061
Schistosoma mansoni histone-lysine n-methyltransferase suv9 0.0051 0.0265 0.0461
Schistosoma mansoni subfamily C14A unassigned peptidase (C14 family) 0.0021 0.0082 0.0142
Schistosoma mansoni DNA polymerase eta 0.0054 0.0287 0.0499
Toxoplasma gondii 'chromo' (CHRromatin Organization MOdifier) domain-containing protein 0.0014 0.0034 0.0762
Giardia lamblia hypothetical protein 0.001 0.0008 0.0147
Schistosoma mansoni growth hormone secretagogue receptor 0.0062 0.0335 0.0582
Brugia malayi hypothetical protein 0.0023 0.0089 0.0231
Trichomonas vaginalis histone deacetylase 1, 2 ,3, putative 0.0029 0.0131 0.073
Trypanosoma brucei ATP-dependent 6-phosphofructokinase, glycosomal 0.0114 0.0665 0.3901
Trichomonas vaginalis set domain proteins, putative 0.0287 0.1747 1
Echinococcus multilocularis bromodomain adjacent to zinc finger domain 0.0026 0.011 0.011
Loa Loa (eye worm) phosphofructokinase 0.0114 0.0665 0.1156
Brugia malayi Ligand-binding domain of nuclear hormone receptor family protein 0.0009 0.0001 0.0003
Brugia malayi SET domain containing protein 0.0016 0.0047 0.0122
Onchocerca volvulus 0.0062 0.0335 0.0871
Schistosoma mansoni cpg binding protein 0.0037 0.0182 0.0317
Trichomonas vaginalis importin beta-1, putative 0.0025 0.0103 0.0565
Echinococcus multilocularis somatostatin receptor 0.0062 0.0335 0.0335
Loa Loa (eye worm) AGC/PKC/ALPHA protein kinase 0.0013 0.0027 0.0047
Onchocerca volvulus 0.0028 0.0123 0.0321
Trichomonas vaginalis carbon catabolite repressor protein, putative 0.001 0.0008 0.002
Brugia malayi Dopamine receptor protein 1, putative (partial) 0.0062 0.0335 0.0871
Echinococcus multilocularis glutamate receptor ionotropic kainate 0.009 0.0514 0.0514
Schistosoma mansoni hypothetical protein 0.0382 0.2345 0.4078
Echinococcus granulosus RUN 0.0028 0.0123 0.0214
Onchocerca volvulus 0.0062 0.0335 0.0871
Echinococcus granulosus snurportin 1 0.0326 0.199 0.3461
Trichomonas vaginalis conserved hypothetical protein 0.0021 0.0082 0.0444
Brugia malayi Endonuclease/Exonuclease/phosphatase family protein 0.001 0.0008 0.002
Echinococcus granulosus tm gpcr rhodopsin 0.0062 0.0335 0.0582
Onchocerca volvulus 0.0025 0.0105 0.0273
Trichomonas vaginalis chromobox protein, putative 0.0084 0.0475 0.2704
Schistosoma mansoni biogenic amine (octopamine/dopamine) receptor 0.0062 0.0335 0.0582
Schistosoma mansoni acetyl-CoA C-acetyltransferase 0.0011 0.0017 0.0029
Trichomonas vaginalis valacyclovir hydrolase, putative 0.0019 0.0066 0.0354
Echinococcus granulosus orexin receptor type 2 0.0062 0.0335 0.0582
Brugia malayi Matrixin family protein 0.0015 0.004 0.0105
Brugia malayi nuclear hormone receptor 0.0009 0.0001 0.0003
Schistosoma mansoni serine/threonine protein kinase 0.0015 0.004 0.007
Onchocerca volvulus 0.0062 0.0335 0.0871
Toxoplasma gondii endonuclease/exonuclease/phosphatase family protein 0.001 0.0008 0.0174
Trypanosoma cruzi Endonuclease/Exonuclease/phosphatase family, putative 0.001 0.0008 0.0045
Echinococcus granulosus ferritin 0.001 0.0012 0.0021
Echinococcus multilocularis peptidase Clp (S14 family) 0.005 0.0262 0.0262
Loa Loa (eye worm) hypothetical protein 0.0009 0.0001 0.0002
Onchocerca volvulus Protein ultraspiracle homolog 0.0009 0.0001 0.0003
Schistosoma mansoni ancient conserved domain protein 2 (cyclin m2) 0.0062 0.0335 0.0582
Loa Loa (eye worm) hypothetical protein 0.0028 0.0123 0.0214
Echinococcus multilocularis neuropeptide FF receptor 2 0.0062 0.0335 0.0335
Trypanosoma cruzi PAB1-binding protein , putative 0.0053 0.0278 0.1633
Schistosoma mansoni histamine-responsive GPCR (AAF21638) 0.0062 0.0335 0.0582
Brugia malayi Nuclear hormone receptor family member nhr-41 0.0009 0.0001 0.0003
Brugia malayi Pre-SET motif family protein 0.0252 0.1529 0.3979
Entamoeba histolytica hypothetical protein 0.0046 0.0238 0.3507
Trichomonas vaginalis conserved hypothetical protein 0.0047 0.0243 0.1373
Schistosoma mansoni peptidase Clp (S14 family) 0.0077 0.0428 0.0744
Echinococcus multilocularis lipoxygenase domain containing protein 0.0028 0.0123 0.0123
Brugia malayi intermediate filament protein 0.0017 0.0055 0.0144
Leishmania major hypothetical protein, conserved 0.001 0.0008 0.0045
Schistosoma mansoni bromodomain containing protein 0.0027 0.0119 0.0206
Loa Loa (eye worm) glutamate receptor 2 0.009 0.0514 0.0894
Loa Loa (eye worm) hypothetical protein 0.0029 0.013 0.0226
Loa Loa (eye worm) hypothetical protein 0.0014 0.0034 0.0059
Mycobacterium ulcerans lipase LipD 0.0016 0.0048 0.0312
Loa Loa (eye worm) hypothetical protein 0.0021 0.0082 0.0142
Loa Loa (eye worm) endonuclease/Exonuclease/phosphatase 0.001 0.0008 0.0013
Trichomonas vaginalis Clan CD, family C14, metacaspase-like cysteine peptidase 0.0021 0.0082 0.0444
Schistosoma mansoni nuclear hormone receptor nor-1/nor-2 0.0009 0.0001 0.0002
Echinococcus granulosus inositol polyphosphate 5 phosphatase OCRL 1 0.001 0.0008 0.0013
Loa Loa (eye worm) hypothetical protein 0.0017 0.0055 0.0096
Brugia malayi RNA binding protein 0.0069 0.0382 0.0994
Loa Loa (eye worm) G-protein coupled receptor 0.0062 0.0335 0.0582
Brugia malayi beta-lactamase 0.0016 0.0048 0.0124
Plasmodium falciparum acyl-CoA synthetase 0.0019 0.0065 0.1523
Onchocerca volvulus 0.0009 0.0001 0.0003
Echinococcus multilocularis histone deacetylase 3 0.0029 0.0131 0.0131
Echinococcus granulosus 6 phosphofructokinase 0.0114 0.0665 0.1156
Echinococcus granulosus nmda type glutamate receptor 0.0411 0.2524 0.4388
Mycobacterium ulcerans beta-lactamase 0.0016 0.0048 0.0312
Schistosoma mansoni histone deacetylase 0.0029 0.0131 0.0228
Echinococcus multilocularis alpha 1A adrenergic receptor 0.0062 0.0335 0.0335
Loa Loa (eye worm) neuropeptide F receptor 0.0062 0.0335 0.0582
Trypanosoma brucei DNA polymerase IV, putative 0.0023 0.0094 0.055
Schistosoma mansoni thyroid hormone receptor 0.0009 0.0001 0.0002
Trichomonas vaginalis phosphofructokinase, putative 0.0031 0.0141 0.0787
Trypanosoma brucei DNA polymerase kappa, putative 0.0016 0.0048 0.0284
Echinococcus multilocularis fmrfamide receptor 0.0062 0.0335 0.0335
Loa Loa (eye worm) neuropeptide F receptor 0.0062 0.0335 0.0582
Echinococcus granulosus g protein coupled receptor 0.0062 0.0335 0.0582
Plasmodium vivax hypothetical protein, conserved 0.0014 0.0034 0.0794
Mycobacterium ulcerans esterase/lipase LipP 0.0016 0.0048 0.0312
Echinococcus multilocularis fetal alzheimer antigen, falz 0.0011 0.0017 0.0017
Loa Loa (eye worm) hypothetical protein 0.0062 0.0335 0.0582
Schistosoma mansoni histone-lysine n-methyltransferase setb1 0.0044 0.0221 0.0385
Giardia lamblia Histone deacetylase 0.0029 0.0131 0.5267
Plasmodium vivax 6-phosphofructokinase, putative 0.0031 0.0141 0.3304
Mycobacterium ulcerans bacterioferritin BfrA 0.001 0.0012 0.0055
Trypanosoma cruzi metacaspase, putative 0.0021 0.0082 0.0479
Treponema pallidum ATP-dependent Clp protease proteolytic subunit 0.0026 0.0113 0.0755
Echinococcus multilocularis g protein coupled receptor 0.0062 0.0335 0.0335
Loa Loa (eye worm) pigment dispersing factor receptor c 0.0065 0.0356 0.0619
Plasmodium falciparum metacaspase 1 0.0021 0.0082 0.1909
Loa Loa (eye worm) animal heme peroxidase 0.0029 0.013 0.0226
Schistosoma mansoni tyrosine kinase 0.0046 0.0238 0.0414
Echinococcus granulosus synaptojanin 1 0.001 0.0008 0.0013
Trichomonas vaginalis phosphofructokinase, putative 0.0114 0.0665 0.3789
Trypanosoma brucei DNA polymerase kappa, putative 0.0023 0.0094 0.055
Loa Loa (eye worm) exodeoxyribonuclease III family protein 0.0048 0.0246 0.0427
Schistosoma mansoni biogenic amine (dopamine) receptor 0.0062 0.0335 0.0582
Loa Loa (eye worm) latrophilin receptor protein 2 0.0021 0.0077 0.0134
Trichomonas vaginalis Clan CD, family C14, metacaspase-like cysteine peptidase 0.0021 0.0082 0.0444
Echinococcus granulosus neuropeptide Y receptor 0.0062 0.0335 0.0582
Trichomonas vaginalis ap endonuclease, putative 0.0048 0.0246 0.1386
Echinococcus multilocularis guanine nucleotide binding protein G(s) subunit 0.0101 0.058 0.058
Echinococcus multilocularis g protein linked acetylcholine receptor gar 2a 0.0062 0.0335 0.0335
Loa Loa (eye worm) heterochromatin protein 1 0.0084 0.0475 0.0827
Chlamydia trachomatis arginine ABC transporter substrate-binding protein ArtJ 0.0232 0.14 1
Echinococcus granulosus neuropeptide FF receptor 2 0.0062 0.0335 0.0582
Loa Loa (eye worm) hypothetical protein 0.0062 0.0335 0.0582
Schistosoma mansoni glutamate receptor AMPA 0.009 0.0514 0.0894
Echinococcus multilocularis g protein coupled receptor 0.0062 0.0335 0.0335
Leishmania major ATP-dependent phosphofructokinase 0.0114 0.0665 0.3901
Echinococcus multilocularis neuropeptide s receptor 0.0062 0.0335 0.0335
Trypanosoma brucei dihydrofolate reductase-thymidylate synthase 0.0067 0.0365 0.2145
Plasmodium falciparum bifunctional dihydrofolate reductase-thymidylate synthase 0.0067 0.0365 0.8546
Brugia malayi cytoplasmic intermediate filament protein 0.0009 0.0005 0.0014
Trypanosoma cruzi pantothenate kinase subunit, putative 0.0011 0.0014 0.0083
Toxoplasma gondii ICE family protease (caspase) p20 domain-containing protein 0.0021 0.0082 0.1833
Echinococcus multilocularis tar DNA binding protein 0.0069 0.0382 0.0382
Brugia malayi thymidylate synthase 0.0047 0.0244 0.0636
Echinococcus multilocularis synaptojanin 1 0.001 0.0008 0.0008
Echinococcus granulosus lamin dm0 0.0017 0.0055 0.0096
Loa Loa (eye worm) nuclear Hormone Receptor family member 0.0009 0.0001 0.0002
Loa Loa (eye worm) hypothetical protein 0.0019 0.0065 0.0113
Mycobacterium tuberculosis Probable ATP-dependent CLP protease proteolytic subunit 1 ClpP1 (endopeptidase CLP) 0.005 0.0262 0.1848
Loa Loa (eye worm) hypothetical protein 0.0025 0.0105 0.0182
Echinococcus granulosus sex peptide receptor 0.0062 0.0335 0.0582
Schistosoma mansoni lipoxygenase 0.0117 0.0682 0.1186
Toxoplasma gondii endonuclease/exonuclease/phosphatase family protein 0.001 0.0008 0.0174
Loa Loa (eye worm) melatonin receptor type 1A 0.0062 0.0335 0.0582
Trichomonas vaginalis Clan CD, family C14, metacaspase-like cysteine peptidase 0.0021 0.0082 0.0444
Schistosoma mansoni peptide (allatostatin/somatostatin)-like receptor 0.0062 0.0335 0.0582
Onchocerca volvulus Peroxidasin homolog 0.0029 0.013 0.0338
Brugia malayi hypothetical protein 0.0046 0.0238 0.062
Loa Loa (eye worm) hypothetical protein 0.0062 0.0335 0.0582
Schistosoma mansoni hypothetical protein 0.0062 0.0335 0.0582
Loa Loa (eye worm) RGC/RGC protein kinase 0.0046 0.0238 0.0414
Echinococcus multilocularis rhodopsin orphan GPCR 0.0062 0.0335 0.0335
Loa Loa (eye worm) hypothetical protein 0.0014 0.0034 0.0059
Mycobacterium leprae ATP-dependent Clp protease proteolytic subunit 1 0.0026 0.0113 0.155
Trichomonas vaginalis chromodomain helicase DNA binding protein, putative 0.0022 0.0083 0.0454
Plasmodium falciparum importin beta, putative 0.003 0.0139 0.3249
Trypanosoma cruzi ATP-dependent 6-phosphofructokinase, glycosomal 0.0114 0.0665 0.3901
Echinococcus granulosus guanine nucleotide binding protein Gs subunit 0.0101 0.058 0.1009
Mycobacterium ulcerans glutamine-binding lipoprotein GlnH 0.0232 0.14 1
Trichomonas vaginalis esterase, putative 0.0016 0.0048 0.025
Trypanosoma brucei mitochondrial DNA polymerase beta-PAK 0.0132 0.0779 0.4571
Brugia malayi Peroxidasin 0.0029 0.013 0.0338
Plasmodium falciparum DNase I-like protein, putative 0.001 0.0008 0.0181
Schistosoma mansoni intermediate filament proteins 0.0017 0.0055 0.0096
Schistosoma mansoni myosin xvIII 0.0062 0.0335 0.0582
Trypanosoma brucei DNA polymerase kappa, putative 0.0023 0.0094 0.055
Brugia malayi Serotonin/octopamine receptor family protein 7 0.0062 0.0335 0.0871
Brugia malayi Nuclear hormone receptor family member nhr-19 0.0009 0.0001 0.0003
Trichomonas vaginalis Clan CD, family C14, metacaspase-like cysteine peptidase 0.0021 0.0082 0.0444
Chlamydia trachomatis ATP-dependent Clp protease proteolytic subunit 0.0077 0.0428 0.2715
Mycobacterium tuberculosis Possible penicillin-binding protein 0.0102 0.0588 0.4178
Leishmania major monoglyceride lipase, putative 0.0019 0.0066 0.0386
Mycobacterium ulcerans phosphopantetheinyl transferase, PptII 0.0025 0.0102 0.0699
Schistosoma mansoni ATP-binding cassette transporter 0.009 0.0515 0.0895
Echinococcus multilocularis nmda type glutamate receptor 0.0411 0.2524 0.2524
Trypanosoma brucei mitochondrial DNA polymerase beta 0.028 0.1704 1
Loa Loa (eye worm) MH2 domain-containing protein 0.0053 0.028 0.0486
Trypanosoma cruzi histone deacetylase 1, putative 0.0029 0.0131 0.0771
Schistosoma mansoni aminoadipate-semialdehyde dehydrogenase 0.0087 0.0496 0.0863
Schistosoma mansoni chromobox protein 0.0084 0.0475 0.0827
Brugia malayi neuropeptide F receptor 0.0062 0.0335 0.0871
Echinococcus multilocularis G protein coupled receptor 139 0.0062 0.0335 0.0335
Brugia malayi hypothetical protein 0.0029 0.013 0.0338
Plasmodium falciparum lysophospholipase, putative 0.0019 0.0066 0.1539
Schistosoma mansoni peptide (FMRFamide/somatostatin)-like receptor 0.0062 0.0335 0.0582
Loa Loa (eye worm) hypothetical protein 0.003 0.0139 0.0242
Echinococcus granulosus dna polymerase kappa 0.0023 0.0094 0.0163
Leishmania major GTP-binding protein, putative 0.0022 0.0088 0.0519
Trypanosoma cruzi Endonuclease/Exonuclease/phosphatase family, putative 0.001 0.0008 0.0045
Echinococcus multilocularis histone lysine N methyltransferase SETMAR 0.0037 0.0178 0.0178
Echinococcus granulosus rhodopsin orphan GPCR 0.0062 0.0335 0.0582
Schistosoma mansoni histone-lysine n-methyltransferase setb1 0.0044 0.0221 0.0385
Schistosoma mansoni biogenic amine (5HT) receptor 0.0925 0.5751 1
Schistosoma mansoni steroid hormone receptor ad4bp 0.0009 0.0001 0.0002
Trypanosoma cruzi metacaspase, putative 0.0021 0.0082 0.0479
Echinococcus multilocularis baculoviral IAP repeat containing protein 0.0015 0.004 0.004
Brugia malayi hypothetical protein 0.0062 0.0335 0.0871
Giardia lamblia GTP-binding nuclear protein RAN/TC4 0.0022 0.0088 0.3487
Schistosoma mansoni hypothetical protein 0.0062 0.0335 0.0582
Echinococcus multilocularis chromobox protein 1 0.0084 0.0475 0.0475
Trichomonas vaginalis histone deacetylase, putative 0.0029 0.0131 0.073
Brugia malayi Endonuclease/Exonuclease/phosphatase family protein 0.001 0.0008 0.002
Loa Loa (eye worm) hypothetical protein 0.0009 0.0001 0.0002
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0062 0.0335 0.0582
Leishmania major hypothetical protein, conserved 0.001 0.0008 0.0045
Echinococcus multilocularis thyrotropin releasing hormone receptor 0.0062 0.0335 0.0335
Loa Loa (eye worm) hypothetical protein 0.0009 0.0001 0.0002
Trypanosoma cruzi mitochondrial DNA polymerase beta-PAK, putative 0.0048 0.0249 0.1459
Trypanosoma brucei histone deacetylase 1 0.0029 0.0131 0.0771
Entamoeba histolytica hypothetical protein 0.0043 0.022 0.3233
Brugia malayi CXXC zinc finger family protein 0.0035 0.0165 0.043
Toxoplasma gondii chromodomain helicase DNA binding protein CHD1/SWI2/SNF2 0.0014 0.0034 0.0762
Echinococcus granulosus mitogen activated protein kinase 0.0015 0.004 0.007
Schistosoma mansoni neutral sphingomyelinase 0.001 0.0008 0.0013
Schistosoma mansoni aldehyde dehydrogenase 0.0079 0.0445 0.0775
Loa Loa (eye worm) nuclear hormone receptor family member nhr-40 0.0009 0.0001 0.0002
Brugia malayi G protein-coupled receptor F59B2.13 0.0062 0.0335 0.0871
Toxoplasma gondii ICE family protease (caspase) p20 domain-containing protein 0.0021 0.0082 0.1833
Leishmania major phosphopantetheinyl transferase-like protein 0.0025 0.0102 0.0598
Plasmodium vivax hypothetical protein, conserved 0.0021 0.0082 0.1909
Trypanosoma cruzi cytochrome P450, putative 0.0013 0.0029 0.0168
Echinococcus multilocularis traf and tnf receptor associated protein 0.001 0.0008 0.0008
Trypanosoma brucei mitogen activated protein kinase 4, putative 0.0015 0.004 0.0235
Schistosoma mansoni glutamate receptor NMDA 0.0299 0.1821 0.3166
Schistosoma mansoni amine GPCR 0.0062 0.0335 0.0582
Trypanosoma brucei DNA polymerase eta, putative 0.0054 0.0287 0.1683
Brugia malayi Guanylyl cyclase protein 23 0.0046 0.0238 0.062
Trypanosoma cruzi metacaspase, putative 0.0021 0.0082 0.0479
Loa Loa (eye worm) beta-lactamase 0.0016 0.0048 0.0083
Echinococcus multilocularis endonuclease exonuclease phosphatase 0.001 0.0008 0.0008
Schistosoma mansoni mixed-lineage leukemia protein mll 0.0075 0.0417 0.0726
Leishmania major metacaspase, putative 0.0021 0.0082 0.0479
Trypanosoma cruzi tyrosyl-DNA Phosphodiesterase (Tdp1), putative 0.0069 0.0383 0.2248
Loa Loa (eye worm) hypothetical protein 0.0062 0.0335 0.0582
Trypanosoma brucei DNA polymerase kappa, putative 0.0023 0.0094 0.055
Loa Loa (eye worm) dihydrofolate reductase 0.0019 0.0069 0.0119
Brugia malayi Dopamine receptor 0.0062 0.0335 0.0871
Schistosoma mansoni ap endonuclease 0.0048 0.0246 0.0427
Schistosoma mansoni biogenic amine (dopamine) receptor 0.0062 0.0335 0.0582
Trypanosoma brucei inositol-1,4,5-trisphosphate (IP3) 5-phosphatase, putative 0.001 0.0008 0.0045
Loa Loa (eye worm) hypothetical protein 0.0017 0.0053 0.0093
Loa Loa (eye worm) hypothetical protein 0.0062 0.0335 0.0582
Trypanosoma brucei GTP-binding nuclear protein rtb2, putative 0.0022 0.0088 0.0519
Trypanosoma brucei DNA-(apurinic or apyrimidinic site) lyase, putative 0.001 0.0008 0.0045
Trichomonas vaginalis CMGC family protein kinase 0.0015 0.004 0.0206
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0062 0.0335 0.0582
Echinococcus granulosus glutamate receptor subunit protein glur 0.009 0.0514 0.0894
Echinococcus multilocularis mixed lineage leukemia protein mll 0.001 0.001 0.001
Onchocerca volvulus 0.0051 0.0265 0.0689
Echinococcus granulosus caspase 0.0021 0.0082 0.0142
Schistosoma mansoni apoferritin-2 0.001 0.0012 0.0021
Echinococcus multilocularis RNA directed DNA polymerase 0.0012 0.0024 0.0024
Schistosoma mansoni tyrosine kinase 0.0046 0.0238 0.0414
Trichomonas vaginalis conserved hypothetical protein 0.0014 0.0034 0.0171
Mycobacterium leprae PROBABLE ATP-DEPENDENT CLP PROTEASE PROTEOLYTIC SUBUNIT 2 CLPP2 (ENDOPEPTIDASE CLP 2) 0.0077 0.0428 0.637
Schistosoma mansoni cript-related 0.001 0.0008 0.0013
Giardia lamblia Endonuclease/Exonuclease/phosphatase 0.0048 0.0246 1
Trypanosoma cruzi mitochondrial DNA polymerase beta, putative 0.028 0.1704 1
Loa Loa (eye worm) hypothetical protein 0.0029 0.013 0.0226
Plasmodium falciparum GTP-binding nuclear protein RAN/TC4 0.0022 0.0088 0.2067
Plasmodium falciparum ataxin-2 like protein, putative 0.0053 0.0278 0.6507
Loa Loa (eye worm) cytochrome P450 family protein 0.0013 0.0029 0.005
Entamoeba histolytica acyl-CoA synthetase, putative 0.0025 0.0105 0.1479
Brugia malayi GnHR receptor homolog 0.0062 0.0335 0.0871
Mycobacterium tuberculosis Inositol-1-monophosphatase SuhB 0.0033 0.0156 0.109
Mycobacterium leprae conserved hypothetical protein 0.0025 0.0102 0.1379
Echinococcus granulosus thyrotropin releasing hormone receptor 0.0062 0.0335 0.0582
Trypanosoma brucei Endonuclease/Exonuclease/phosphatase family, putative 0.001 0.0008 0.0045
Echinococcus multilocularis terminal deoxycytidyl transferase rev1 0.0023 0.0094 0.0094
Trichomonas vaginalis Clan CD, family C14, metacaspase-like cysteine peptidase 0.0021 0.0082 0.0444
Brugia malayi Iron-sulfur cluster assembly accessory protein 0.0042 0.0209 0.0545
Treponema pallidum ATP-dependent Clp protease proteolytic subunit 0.0077 0.0428 0.3015
Echinococcus multilocularis nmda type glutamate receptor 0.0686 0.4253 0.4253
Echinococcus multilocularis dro:myosuppressin receptor 0.0062 0.0335 0.0335
Onchocerca volvulus 0.0037 0.018 0.0467
Schistosoma mansoni chromodomain helicase DNA binding protein 0.0014 0.0034 0.0059
Brugia malayi gonadotropin-releasing hormone receptor 2 0.0062 0.0335 0.0871
Brugia malayi G protein-coupled receptor 0.0062 0.0335 0.0871
Loa Loa (eye worm) hypothetical protein 0.0062 0.0335 0.0582
Plasmodium falciparum chromodomain-helicase-DNA-binding protein 1 homolog, putative 0.0014 0.0034 0.0794
Leishmania major mitochondrial DNA polymerase beta-PAK, putative 0.0132 0.0779 0.4571
Mycobacterium leprae PROBABLE ATP-DEPENDENT CLP PROTEASE PROTEOLYTIC SUBUNIT 1 CLPP1 (ENDOPEPTIDASE CLP) 0.005 0.0262 0.3836
Schistosoma mansoni peroxidasin 0.0029 0.013 0.0226
Loa Loa (eye worm) nuclear hormone receptor family member nhr-41 0.0009 0.0001 0.0002
Echinococcus multilocularis ecdysone induced protein 78C 0.0009 0.0001 0.0001
Trypanosoma brucei DNA polymerase kappa, putative 0.0016 0.0048 0.0284
Loa Loa (eye worm) matrixin family protein 0.0015 0.004 0.007
Loa Loa (eye worm) hypothetical protein 0.0046 0.0238 0.0414
Onchocerca volvulus 0.0062 0.0335 0.0871
Wolbachia endosymbiont of Brugia malayi fructose-1,6-bisphosphatase 0.0037 0.0181 0.4063
Echinococcus multilocularis peptide (allatostatin:somatostatin) 0.0062 0.0335 0.0335
Echinococcus granulosus atrial natriuretic peptide receptor 0.0046 0.0238 0.0414
Schistosoma mansoni inositol monophosphatase 0.0037 0.0181 0.0314
Echinococcus granulosus glutamate NMDA receptor subunit 0.0299 0.1821 0.3166
Schistosoma mansoni 6-phosphofructokinase 0.0114 0.0665 0.1156
Loa Loa (eye worm) hypothetical protein 0.0062 0.0335 0.0582
Schistosoma mansoni opsin-like receptor 0.0062 0.0335 0.0582
Trichomonas vaginalis type IV inositol 5-phosphatase, putative 0.001 0.0008 0.002
Schistosoma mansoni survival motor neuron protein 0.0042 0.0209 0.0364
Echinococcus granulosus terminal deoxycytidyl transferase rev1 0.0023 0.0094 0.0163
Schistosoma mansoni importin beta-1 0.003 0.0139 0.0242
Loa Loa (eye worm) hypothetical protein 0.005 0.0263 0.0458
Loa Loa (eye worm) hypothetical protein 0.0053 0.0278 0.0484
Echinococcus granulosus tachykinin peptides receptor 99D 0.0062 0.0335 0.0582
Echinococcus multilocularis atrial natriuretic peptide receptor 0.0046 0.0238 0.0238
Echinococcus granulosus neuropeptide receptor A26 0.0062 0.0335 0.0582
Onchocerca volvulus 0.0046 0.0238 0.062
Schistosoma mansoni Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) 0.0101 0.058 0.1009
Loa Loa (eye worm) unidentified vitellogenin-linked transcript protein 6 0.0062 0.0335 0.0582
Loa Loa (eye worm) hypothetical protein 0.0046 0.0238 0.0414
Echinococcus multilocularis mitogen activated protein kinase 0.0015 0.004 0.004
Onchocerca volvulus 0.0029 0.013 0.0338
Echinococcus granulosus FTZ F1 alpha 0.0009 0.0001 0.0002
Loa Loa (eye worm) gonadotropin-releasing hormone receptor 2 0.0062 0.0335 0.0582
Onchocerca volvulus 0.0062 0.0335 0.0871
Brugia malayi Nuclear hormone receptor family member nhr-3 0.0009 0.0001 0.0003
Schistosoma mansoni rab6-interacting 0.0028 0.0123 0.0214
Trichomonas vaginalis conserved hypothetical protein 0.0023 0.0089 0.0485
Plasmodium vivax ataxin-2 like protein, putative 0.0053 0.0278 0.6507
Echinococcus multilocularis 7TM GPCR, rhodopsin 0.0062 0.0335 0.0335
Echinococcus multilocularis geminin 0.0382 0.2345 0.2345
Brugia malayi Metabotropic glutamate receptor precursor. 0.0046 0.0238 0.062
Trypanosoma cruzi endonuclease/exonuclease/phosphatase, putative 0.001 0.0008 0.0045
Echinococcus granulosus neutral sphingomyelinase 0.001 0.0008 0.0013
Trichomonas vaginalis inositol monophosphatase, putative 0.0037 0.0181 0.1013
Toxoplasma gondii hypothetical protein 0.0045 0.0231 0.5182
Echinococcus multilocularis tyrosyl DNA phosphodiesterase 1 0.0069 0.0383 0.0383
Entamoeba histolytica hydrolase, alpha/beta fold family domain containing protein 0.0019 0.0066 0.0884
Schistosoma mansoni hypothetical protein 0.0043 0.022 0.0383
Echinococcus granulosus glutamate receptor 2 0.0046 0.0238 0.0414
Brugia malayi Sulfatase family protein 0.0009 0.0004 0.0011
Toxoplasma gondii LsmAD domain-containing protein 0.0053 0.0278 0.6247
Echinococcus multilocularis thymidylate synthase 0.0047 0.0244 0.0244
Trypanosoma cruzi metacaspase 5, putative 0.0021 0.0082 0.0479
Plasmodium vivax multidomain scavenger receptor, putative 0.0028 0.0123 0.2881
Giardia lamblia Inositol 5-phosphatase 4 0.001 0.0008 0.0147
Trypanosoma brucei DNA polymerase IV, putative 0.0023 0.0094 0.055
Loa Loa (eye worm) hypothetical protein 0.0062 0.0335 0.0582
Chlamydia trachomatis fructose-6-phosphate phosphotransferase 0.0031 0.0141 0.057
Trypanosoma brucei DNA polymerase kappa, putative 0.0023 0.0094 0.055
Leishmania major tyrosyl-DNA phosphodiesterase 1 0.0069 0.0383 0.2248
Brugia malayi hypothetical protein 0.0062 0.0335 0.0871
Toxoplasma gondii phosphofructokinase PFKII 0.0031 0.0141 0.3172
Onchocerca volvulus 0.0062 0.0335 0.0871
Schistosoma mansoni histone-lysine n-methyltransferase setb1 0.0037 0.0178 0.031
Mycobacterium ulcerans hypothetical protein 0.0019 0.0066 0.0441
Echinococcus multilocularis dna polymerase kappa 0.0023 0.0094 0.0094
Brugia malayi AMP-binding enzyme family protein 0.0025 0.0105 0.0273
Echinococcus granulosus retinoic acid receptor rxr beta a 0.0009 0.0001 0.0002
Mycobacterium tuberculosis Possible conserved lipoprotein LpqK 0.0016 0.0048 0.0312
Loa Loa (eye worm) RNA recognition domain-containing protein domain-containing protein 0.0069 0.0382 0.0664
Schistosoma mansoni aldehyde dehydrogenase 0.0079 0.0445 0.0775
Brugia malayi beta-lactamase family protein 0.0016 0.0048 0.0124
Brugia malayi hypothetical protein 0.0062 0.0335 0.0871
Trypanosoma brucei inositol-1(or 4)-monophosphatase 1, putative 0.0037 0.0181 0.1061
Leishmania major 4-coumarate:coa ligase-like protein 0.0025 0.0105 0.0616
Schistosoma mansoni loxhd1 0.0028 0.0123 0.0214
Loa Loa (eye worm) animal heme peroxidase 0.0029 0.013 0.0226
Echinococcus multilocularis g protein coupled receptor 0.0062 0.0335 0.0335
Mycobacterium ulcerans acyl-CoA synthetase 0.0025 0.0105 0.0721
Mycobacterium ulcerans long-chain fatty-acid CoA ligase 0.0025 0.0105 0.0721
Loa Loa (eye worm) hypothetical protein 0.0925 0.5751 1
Trichomonas vaginalis Importin beta-1 subunit, putative 0.0025 0.0103 0.0565
Brugia malayi AMP-binding enzyme family protein 0.0025 0.0105 0.0273
Loa Loa (eye worm) hypothetical protein 0.0019 0.0065 0.0113
Schistosoma mansoni glutamate receptor kainate 0.009 0.0514 0.0894
Loa Loa (eye worm) G-protein-linked acetylcholine receptor protein 2 0.0062 0.0335 0.0582
Echinococcus granulosus neuropeptide s receptor 0.0062 0.0335 0.0582
Echinococcus granulosus Chromobox protein 3 0.0014 0.0034 0.0059
Trichomonas vaginalis chromobox protein, putative 0.0014 0.0034 0.0171
Echinococcus multilocularis CCR4 NOT transcription complex subunit 6 0.001 0.0008 0.0008
Echinococcus multilocularis dihydrofolate reductase 0.0019 0.0069 0.0069
Loa Loa (eye worm) hypothetical protein 0.0014 0.0034 0.0059
Loa Loa (eye worm) transcription factor SMAD2 0.0053 0.028 0.0486
Schistosoma mansoni hypothetical protein 0.0028 0.0123 0.0214
Schistosoma mansoni tar DNA-binding protein 0.0069 0.0382 0.0664
Schistosoma mansoni rab6-interacting 0.0028 0.0123 0.0214
Loa Loa (eye worm) hypothetical protein 0.005 0.0263 0.0458
Mycobacterium ulcerans thymidylate synthase 0.0047 0.0244 0.172
Echinococcus granulosus survival motor neuron protein 1 0.0205 0.1232 0.2142
Echinococcus multilocularis 6 phosphofructokinase 0.0114 0.0665 0.0665
Brugia malayi ecdysteroid receptor 0.0009 0.0001 0.0003
Echinococcus granulosus tm gpcr rhodopsin 0.0062 0.0335 0.0582
Plasmodium falciparum ATP-dependent 6-phosphofructokinase 0.0031 0.0141 0.3304
Echinococcus multilocularis glutamate receptor 2 0.009 0.0514 0.0514
Toxoplasma gondii ATP-dependent Clp endopeptidase, proteolytic subunit ClpP domain-containing protein 0.0077 0.0428 0.96
Echinococcus multilocularis muscleblind protein 1 0.005 0.0263 0.0263
Schistosoma mansoni nocturnin 0.001 0.0008 0.0013
Trichomonas vaginalis phosphofructokinase, putative 0.0031 0.0141 0.0787
Onchocerca volvulus Heterochromatin protein 1 homolog 0.0051 0.0266 0.0692
Mycobacterium ulcerans ATP-dependent Clp protease proteolytic subunit 0.0077 0.0428 0.3033
Mycobacterium tuberculosis Fatty-acid-AMP ligase FadD30 (fatty-acid-AMP synthetase) (fatty-acid-AMP synthase) 0.0019 0.0065 0.0436
Loa Loa (eye worm) hypothetical protein 0.0045 0.0227 0.0394
Trichomonas vaginalis histone deacetylase 1, 2 ,3, putative 0.0029 0.0131 0.073
Echinococcus multilocularis histone lysine methyltransferase setb histone lysine methyltransferase eggless 0.0044 0.0221 0.0221
Leishmania major DNA polymerase kappa, putative 0.0023 0.0094 0.055
Onchocerca volvulus Heterochromatin protein 1 homolog 0.0047 0.0243 0.0633
Mycobacterium tuberculosis Possible lysophospholipase 0.0019 0.0066 0.0441
Brugia malayi Nuclear hormone receptor family member nhr-14 0.0009 0.0001 0.0003
Loa Loa (eye worm) hypothetical protein 0.0077 0.0428 0.0744
Trypanosoma cruzi Endonuclease/Exonuclease/phosphatase family, putative 0.001 0.0008 0.0045
Brugia malayi Probable ClpP-like protease 0.0077 0.0428 0.1113
Toxoplasma gondii histone lysine methyltransferase SET1 0.0068 0.0374 0.8398
Schistosoma mansoni neuropeptide F-like receptor 0.0062 0.0335 0.0582
Trichomonas vaginalis conserved hypothetical protein 0.0021 0.0082 0.0444
Echinococcus multilocularis rhodopsin orphan GPCR 0.0062 0.0335 0.0335
Schistosoma mansoni hypothetical protein 0.005 0.026 0.0452
Loa Loa (eye worm) hypothetical protein 0.0062 0.0335 0.0582
Echinococcus multilocularis neuropeptide receptor 0.0062 0.0335 0.0335
Plasmodium falciparum ataxin-2 like protein, putative 0.0053 0.0278 0.6507
Mycobacterium ulcerans 4'-phosphopantetheinyl transferase 0.0025 0.0102 0.0699
Brugia malayi Cytochrome P450 family protein 0.0013 0.0029 0.0075
Trichomonas vaginalis conserved hypothetical protein 0.0014 0.0034 0.0171
Echinococcus granulosus histone deacetylase 1 0.0029 0.0131 0.0228
Trypanosoma cruzi RNA-editing complex protein MP100, putative 0.001 0.0008 0.0045
Schistosoma mansoni chromobox protein 0.0084 0.0475 0.0827
Leishmania major DNA polymerase eta, putative 0.0054 0.0287 0.1683
Schistosoma mansoni Tr4/Tr2 (homologue) 0.0009 0.0001 0.0002
Mycobacterium leprae Probable lipase LipE 0.0016 0.0048 0.0551
Loa Loa (eye worm) blistered cuticle protein 3 0.0029 0.013 0.0226
Echinococcus granulosus CCR4 NOT transcription complex subunit 6 0.001 0.0008 0.0013
Echinococcus multilocularis chromobox protein 1 0.0084 0.0475 0.0475
Echinococcus granulosus glutamate receptor ionotropic kainate 0.009 0.0514 0.0894
Chlamydia trachomatis glutamine binding protein 0.0232 0.14 1
Loa Loa (eye worm) hypothetical protein 0.0046 0.0238 0.0414
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0062 0.0335 0.0582
Echinococcus granulosus L aminoadipate semialdehyde 0.0087 0.0496 0.0863
Onchocerca volvulus 0.0062 0.0335 0.0871
Loa Loa (eye worm) 6-phosphofructokinase 0.0114 0.0665 0.1156
Loa Loa (eye worm) hypothetical protein 0.0015 0.004 0.0069
Loa Loa (eye worm) hypothetical protein 0.0062 0.0335 0.0582
Toxoplasma gondii hypothetical protein 0.0026 0.0113 0.2536
Treponema pallidum 4'-phosphopantetheinyl transferase 0.0025 0.0102 0.0675
Trichomonas vaginalis chromobox protein, putative 0.0014 0.0034 0.0171
Plasmodium vivax holo-[acyl-carrier-protein] synthase, putative 0.0025 0.0102 0.2381
Trypanosoma brucei inositol/phosphatidylinositol phosphatase, putative 0.001 0.0008 0.0045
Echinococcus granulosus G protein coupled receptor 139 0.0062 0.0335 0.0582
Loa Loa (eye worm) hypothetical protein 0.0062 0.0335 0.0582
Trypanosoma brucei DNA polymerase kappa, putative 0.0023 0.0094 0.055
Brugia malayi Endonuclease/Exonuclease/phosphatase family protein 0.001 0.0008 0.002
Toxoplasma gondii endonuclease/exonuclease/phosphatase family protein 0.001 0.0008 0.0174
Schistosoma mansoni caspase-3 (C14 family) 0.0021 0.0082 0.0142
Echinococcus multilocularis rhodopsin orphan GPCR 0.0062 0.0335 0.0335
Onchocerca volvulus 0.0062 0.0335 0.0871
Schistosoma mansoni lamin 0.0017 0.0055 0.0096
Leishmania major apurinic/apyrimidinic endonuclease-redox protein 0.0048 0.0246 0.1442
Plasmodium vivax AP endonuclease (DNA-[apurinic or apyrimidinic site] lyase), putative 0.0048 0.0246 0.5745
Trypanosoma brucei metacaspase MCA2 0.0021 0.0082 0.0479
Brugia malayi histone deacetylase 1 (HD1) 0.0029 0.0131 0.0342
Schistosoma mansoni hypothetical protein 0.0042 0.0209 0.0364
Trypanosoma brucei cytochrome P450, putative 0.0013 0.0029 0.0168
Loa Loa (eye worm) nuclear hormone receptor family member nhr-1 0.0009 0.0001 0.0002
Loa Loa (eye worm) thymidylate synthase 0.0047 0.0244 0.0425
Trypanosoma cruzi apurinic/apyrimidinic endonuclease, putative 0.001 0.0008 0.0045
Schistosoma mansoni coup transcription factor 0.0009 0.0001 0.0002
Trypanosoma brucei DNA polymerase kappa, putative 0.0023 0.0094 0.055
Toxoplasma gondii GTP-binding nuclear protein ran/tc4 0.0022 0.0088 0.1985
Trypanosoma brucei hypothetical protein, conserved 0.0025 0.0102 0.0598
Onchocerca volvulus Deterin homolog 0.0015 0.004 0.0103
Toxoplasma gondii ATP-dependent Clp endopeptidase, proteolytic subunit ClpP domain-containing protein 0.0077 0.0428 0.96
Plasmodium falciparum ATP-dependent Clp protease proteolytic subunit 0.0026 0.0113 0.2642
Echinococcus granulosus peroxidasin 0.0029 0.013 0.0226
Loa Loa (eye worm) hypothetical protein 0.0014 0.0034 0.0059
Loa Loa (eye worm) hypothetical protein 0.0021 0.0077 0.0134
Mycobacterium ulcerans DNA polymerase IV 0.0023 0.0094 0.0642
Treponema pallidum bacterioferrin (TpF1) 0.001 0.0012 0.0029
Trypanosoma cruzi DNA polymerase kappa, putative 0.0023 0.0094 0.055
Echinococcus granulosus 5'partial|histone lysine N methyltransferase SETDB2 0.0035 0.0165 0.0288
Brugia malayi Latrophilin receptor protein 2 0.0021 0.0077 0.02
Echinococcus granulosus pyroglutamylated rfamide peptide receptor 0.0062 0.0335 0.0582
Schistosoma mansoni biogenic amine receptor 0.0062 0.0335 0.0582
Schistosoma mansoni alpha-1 adrenergic receptor 0.0062 0.0335 0.0582
Schistosoma mansoni synaptojanin 0.001 0.0008 0.0013
Echinococcus granulosus chromodomain helicase DNA binding protein 4 0.0017 0.0051 0.0089
Echinococcus multilocularis GPCR, family 2 0.0021 0.0077 0.0077
Onchocerca volvulus 0.0062 0.0335 0.0871
Loa Loa (eye worm) hypothetical protein 0.0062 0.0335 0.0582
Echinococcus multilocularis beta LACTamase domain containing family member 0.0016 0.0048 0.0048
Treponema pallidum diphosphate--fructose-6-phosphate 1-phosphotransferase 0.0031 0.0141 0.0959

Activities

Activity type Activity value Assay description Source Reference
Potency (functional) 6.5131 uM PUBCHEM_BIOASSAY: Nrf2 qHTS screen for inhibitors. (Class of assay: confirmatory) [Related pubchem assays (depositor defined):AID493153, AID493163, AID504648] ChEMBL. No reference
Potency (functional) 8.1961 uM PUBCHEM_BIOASSAY: qHTS screen for small molecules that inhibit ELG1-dependent DNA repair in human embryonic kidney (HEK293T) cells expressing luciferase-tagged ELG1. (Class of assay: confirmatory) [Related pubchem assays (depositor defined):AID493107, AID493125] ChEMBL. No reference
Potency (functional) 8.1995 uM PubChem BioAssay. A quantitative high throughput screen for small molecules that induce DNA re-replication in SW480 colon adenocarcinoma cells. (Class of assay: confirmatory) ChEMBL. No reference
Potency (functional) = 8.9125 um PUBCHEM_BIOASSAY: qHTS Fluorescence Polarization Assay for Inhibitors of MLL CXXC domain - DNA interaction. (Class of assay: confirmatory) [Related pubchem assays: 2698 (Summary assay.)] ChEMBL. No reference
Potency (functional) 10 uM PUBCHEM_BIOASSAY: qHTS Assay for Inhibitors of Histone Lysine Methyltransferase G9a. (Class of assay: confirmatory) [Related pubchem assays (depositor defined):AID504404] ChEMBL. No reference
Potency (functional) 10.4179 uM PUBCHEM_BIOASSAY: Primary qHTS for delayed death inhibitors of the malarial parasite plastid, 48 hour incubation. (Class of assay: confirmatory) [Related pubchem assays (depositor defined):AID488752, AID488774, AID504848, AID504850] ChEMBL. No reference
Potency (binding) = 12.5893 um PUBCHEM_BIOASSAY: qHTS Assay for Identification of Novel General Anesthetics. In this assay, a GABAergic mimetic model system, apoferritin and a profluorescent 1-aminoanthracene ligand (1-AMA), was used to construct a competitive binding assay for identification of novel general anesthetics (Class of assay: confirmatory) [Related pubchem assays: 2385 (Probe Development Summary for Identification of Novel General Anesthetics), 2323 (Validation apoferritin assay run on SigmaAldrich LOPAC1280 collection)] ChEMBL. No reference
Potency (functional) 12.5893 uM PUBCHEM_BIOASSAY: qHTS for Inhibitors of Polymerase Eta. (Class of assay: confirmatory) [Related pubchem assays (depositor defined):AID588636] ChEMBL. No reference
Potency (functional) 17.7828 uM PUBCHEM_BIOASSAY: HTS for Inhibitors of HP1-beta Chromodomain Interactions with Methylated Histone Tails. (Class of assay: confirmatory) [Related pubchem assays (depositor defined):AID488962] ChEMBL. No reference
Potency (functional) 18.3564 uM PubChem BioAssay. A quantitative high throughput screen for small molecules that induce DNA re-replication in MCF 10a normal breast cells. (Class of assay: confirmatory) ChEMBL. No reference
Potency (functional) 28.1838 uM PubChem BioAssay. qHTS of GLP-1 Receptor Inverse Agonists (Inhibition Mode). (Class of assay: confirmatory) ChEMBL. No reference
Potency (functional) 28.1838 uM PubChem BioAssay. qHTS Assay to Find Inhibitors of Pin1. (Class of assay: confirmatory) ChEMBL. No reference
Potency (functional) 39.8107 uM PUBCHEM_BIOASSAY: qHTS Assay for Inhibitors of BAZ2B. (Class of assay: confirmatory) [Related pubchem assays (depositor defined):AID504391] ChEMBL. No reference
Potency (functional) = 44.6684 um PUBCHEM_BIOASSAY: qHTS Assay for the Inhibitors of Schistosoma Mansoni Peroxiredoxins. (Class of assay: confirmatory) [Related pubchem assays: 1011 (Confirmation Concentration-Response Assay for Inhibitors of the Schistosoma mansoni Redox Cascade ), 448 (Schistosoma Mansoni Peroxiredoxins (Prx2) and thioredoxin glutathione reductase (TGR) coupled assay)] ChEMBL. No reference
Potency (functional) 44.6684 uM PUBCHEM_BIOASSAY: Inhibitors of Regulator of G Protein Signaling (RGS) 4: qHTS. (Class of assay: confirmatory) [Related pubchem assays (depositor defined):AID504856] ChEMBL. No reference
Potency (functional) 44.6684 uM PUBCHEM_BIOASSAY: qHTS for Inhibitors of Polymerase Iota. (Class of assay: confirmatory) [Related pubchem assays (depositor defined):AID588623] ChEMBL. No reference
Potency (functional) 50.1187 uM PUBCHEM_BIOASSAY: qHTS Assay for Inhibitors of JMJD2A-Tudor Domain. (Class of assay: confirmatory) [Related pubchem assays (depositor defined):AID504402] ChEMBL. No reference
Potency (functional) 50.1187 uM PUBCHEM_BIOASSAY: qHTS Assay for Inhibitors of Mammalian Selenoprotein Thioredoxin Reductase 1 (TrxR1): qHTS. (Class of assay: confirmatory) [Related pubchem assays (depositor defined):AID488771] ChEMBL. No reference
Potency (functional) = 56.2341 um PUBCHEM_BIOASSAY: qHTS Assay for Inhibitors of Bacillus subtilis Sfp phosphopantetheinyl transferase (PPTase). (Class of assay: confirmatory) ChEMBL. No reference

Phenotypes

Whole-cell/tissue/organism interactions

Species name Source Reference Is orphan
Plasmodium falciparum ChEMBL23

Many chemical entities in TDR Targets come from high-throughput screenings with whole cells or tissue samples, and not all assayed compounds have been tested against a single a single target protein, probably because they get ruled out during screening process. Even if these compounds may have not been of interest in the original screening, they may come as interesting leads for other screening assays. Furthermore, we may be able to propose drug-target associations using chemical similarities and network patterns.

Annotated phenotypes:

We have no manually annotated phenotypes for this drug. What does this mean? / Care to help?
In TDR Targets, information about phenotypes that are caused by drugs, or by genetic manipulation of cells (e.g. gene knockouts or knockdowns) is manually curated from the literature. These descriptions help to describe the potential of the target for drug development. If no information is available for this gene or if the information is incomplete, this may mean that i) the papers containing this information either appeared after the curation effort for this organism was carried out or they were inadvertently missed by curators; or that ii) the curation effort for this organism has not yet started.
 
In any case, if you have information about papers containing relevant validation data for this target, please log in using your TDR Targets username and password and send them to us using the corresponding form in this page (only visible to registered users) or contact us.

External resources for this compound

Bibliographic References

No literature references available for this target.

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