Detailed information for compound 1442348

Basic information

Technical information
  • Name: Unnamed compound
  • MW: 481.582 | Formula: C26H28FN3O3S
  • H donors: 2 H acceptors: 3 LogP: 4.27 Rotable bonds: 8
    Rule of 5 violations (Lipinski): 1
  • SMILES: O=C(c1cccc(c1)NS(=O)(=O)c1ccc(c(c1)F)C)NC1CCN(CC1)Cc1ccccc1
  • InChi: 1S/C26H28FN3O3S/c1-19-10-11-24(17-25(19)27)34(32,33)29-23-9-5-8-21(16-23)26(31)28-22-12-14-30(15-13-22)18-20-6-3-2-4-7-20/h2-11,16-17,22,29H,12-15,18H2,1H3,(H,28,31)
  • InChiKey: DBCUBSHSBILWMT-UHFFFAOYSA-N  


Substructure search Similarity search

Network

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Synonyms

No synonyms found for this compound

Targets

Known targets for this compound

Species Target name Source Bibliographic reference
Homo sapiens glucagon-like peptide 1 receptor Starlite/ChEMBL No references
Homo sapiens nuclear factor, erythroid 2-like 2 Starlite/ChEMBL No references

Predicted pathogen targets for this compound

By orthology
No druggable targets predicted by orthology data
By sequence similarity to non orthologous known druggable targets
Species Potential target Known druggable target Length Alignment span Identity
Loa Loa (eye worm) pigment dispersing factor receptor c glucagon-like peptide 1 receptor 463 aa 388 aa 25.8 %
Obtained from network model

Ranking Plot

Putative Targets List

Species Potential target Raw Global Species
Schistosoma mansoni adrenodoxin 0.0029 0.0085 0.0087
Leishmania major ferredoxin 2fe-2s-like protein 0.0029 0.0085 0.0548
Trypanosoma brucei fructose-bisphosphate aldolase, glycosomal, putative 0.0093 0.0543 0.3917
Echinococcus granulosus fetal alzheimer antigen falz 0.0026 0.007 0.0071
Echinococcus granulosus GPCR family 2 0.0019 0.0018 0.0018
Echinococcus multilocularis cpg binding protein 0.0063 0.0331 0.0339
Brugia malayi nuclear hormone receptor family member odr-7 0.0028 0.008 0.0204
Trichomonas vaginalis PIKK family atypical protein kinase 0.0018 0.001 0.0006
Trypanosoma brucei iron superoxide dismutase 0.0068 0.0367 0.2639
Trypanosoma cruzi myo-inositol-1(or 4)-monophosphatase 1, putative 0.0038 0.0151 0.1072
Schistosoma mansoni glyceraldehyde-3-phosphate dehydrogenase (phosphorylating) 0.007 0.0376 0.0385
Trichomonas vaginalis PIKK family atypical protein kinase 0.0018 0.001 0.0006
Entamoeba histolytica rodhanase-like domain containing protein 0.0116 0.0706 0.1715
Trichomonas vaginalis CAMK family protein kinase 0.0094 0.0551 0.0883
Schistosoma mansoni single-minded 0.005 0.0236 0.0242
Mycobacterium tuberculosis Probable esterase LipL 0.0037 0.0144 0.0126
Schistosoma mansoni coup transcription factor 0.0059 0.03 0.0308
Loa Loa (eye worm) hypothetical protein 0.0026 0.0069 0.0176
Echinococcus multilocularis FTZ F1 nuclear receptor protein 0.0059 0.03 0.0308
Trypanosoma cruzi pyruvate kinase 2, putative 0.0067 0.036 0.2589
Schistosoma mansoni cpg binding protein 0.0063 0.0331 0.0339
Mycobacterium ulcerans aldehyde dehydrogenase 0.0122 0.0752 0.0731
Mycobacterium ulcerans lipoprotein LpqF 0.0063 0.0331 0.0309
Leishmania major dihydrolipoamide dehydrogenase, putative 0.0035 0.0134 0.0903
Onchocerca volvulus 0.01 0.0591 0.1712
Echinococcus granulosus fructose 16 bisphosphate aldolase 0.0093 0.0543 0.0556
Plasmodium falciparum glyceraldehyde-3-phosphate dehydrogenase 0.007 0.0376 0.6065
Leishmania major phosphatidylinositol kinase related protein, putative 0.0018 0.001 0.0002
Loa Loa (eye worm) hypothetical protein 0.0039 0.0158 0.0404
Giardia lamblia Kinase, PLK 0.0094 0.0551 0.1334
Schistosoma mansoni thyroid hormone receptor 0.0184 0.1188 0.1216
Loa Loa (eye worm) 2Fe-2S iron-sulfur cluster binding domain-containing protein 0.0029 0.0085 0.0218
Toxoplasma gondii N-acetylglucosaminylphosphatidylinositol deacetylase 0.0047 0.0216 0.2781
Onchocerca volvulus Superoxide dismutase [Mn], mitochondrial homolog 0.0068 0.0367 0.1023
Loa Loa (eye worm) hypothetical protein 0.0098 0.0576 0.1478
Plasmodium falciparum pyruvate kinase 0.0067 0.036 0.5797
Loa Loa (eye worm) hypothetical protein 0.0023 0.0044 0.0112
Schistosoma mansoni transcription factor LCR-F1 0.0043 0.0191 0.0195
Mycobacterium leprae Probable lipase LipE 0.0037 0.0144 0.011
Echinococcus multilocularis musashi 0.0054 0.0269 0.0275
Loa Loa (eye worm) hypothetical protein 0.0031 0.0103 0.0265
Echinococcus granulosus glyceraldehyde 3 phosphate dehydrogenase 0.0046 0.0206 0.0211
Schistosoma mansoni blooms syndrome DNA helicase 0.0017 0.0005 0.0005
Leishmania major iron superoxide dismutase, putative 0.0068 0.0367 0.2604
Echinococcus multilocularis mitogen activated protein kinase 0.0053 0.0255 0.0261
Brugia malayi hypothetical protein 0.0167 0.107 0.2744
Trypanosoma cruzi fructose-bisphosphate aldolase, glycosomal, putative 0.0093 0.0543 0.3917
Loa Loa (eye worm) hypothetical protein 0.0028 0.008 0.0204
Echinococcus granulosus COUP TF:Svp nuclear hormone receptor 0.0059 0.03 0.0308
Schistosoma mansoni adrenodoxin 0.0029 0.0085 0.0087
Trichomonas vaginalis cdc25b, putative 0.0116 0.0706 0.1133
Mycobacterium tuberculosis Hypothetical oxidoreductase 0.0029 0.0085 0.0065
Giardia lamblia DINP protein human, muc B family 0.002 0.0023 0.0032
Schistosoma mansoni hypothetical protein 0.0825 0.574 0.5878
Trichomonas vaginalis PIKK family atypical protein kinase 0.0018 0.001 0.0006
Schistosoma mansoni microtubule-associated protein tau 0.1392 0.9765 1
Trypanosoma cruzi fructose-bisphosphate aldolase, glycosomal, putative 0.0093 0.0543 0.3917
Brugia malayi fructose-bisphosphate aldolase 1 0.0093 0.0543 0.1393
Toxoplasma gondii aldehyde dehydrogenase 0.0122 0.0752 1
Echinococcus multilocularis Polycystic kidney disease protein 0.0023 0.0044 0.0045
Chlamydia trachomatis dihydrolipoyl dehydrogenase 0.0035 0.0134 0.2905
Brugia malayi Nuclear hormone receptor E75 0.0028 0.008 0.0204
Brugia malayi Ligand-binding domain of nuclear hormone receptor family protein 0.0059 0.03 0.0771
Trypanosoma cruzi hypothetical protein, conserved 0.0029 0.0085 0.0592
Echinococcus multilocularis fetal alzheimer antigen, falz 0.0026 0.007 0.0071
Trichomonas vaginalis fructose-bisphosphate aldolase, putative 0.059 0.4068 0.6574
Echinococcus multilocularis 0.0021 0.0034 0.0035
Mycobacterium tuberculosis Probable fructose-bisphosphate aldolase Fba 0.0288 0.1927 0.1975
Leishmania major hypothetical protein, conserved 0.0051 0.0243 0.1703
Onchocerca volvulus Huntingtin homolog 0.0122 0.0746 0.2189
Trypanosoma brucei DNA polymerase kappa, putative 0.002 0.0023 0.0141
Leishmania major DNA polymerase kappa, putative,DNA polymerase IV, putative 0.002 0.0023 0.0094
Onchocerca volvulus 0.0058 0.0294 0.0798
Trichomonas vaginalis glutathione reductase, putative 0.0035 0.0134 0.0207
Leishmania major pyruvate kinase 0.0067 0.036 0.2554
Brugia malayi hypothetical protein 0.0051 0.0243 0.0624
Trichomonas vaginalis myo inositol monophosphatase, putative 0.0038 0.0151 0.0235
Leishmania major protein kinase, putative,polo-like protein kinase, putative 0.0094 0.0551 0.3948
Brugia malayi glutathione reductase 0.0102 0.0607 0.1558
Brugia malayi Pyruvate kinase, M2 isozyme 0.0067 0.036 0.0924
Echinococcus granulosus manganese superoxide dismutase 0.0068 0.0367 0.0376
Trichomonas vaginalis PIKK family atypical protein kinase 0.0018 0.001 0.0006
Trypanosoma brucei target of rapamycin kinase 3, putative 0.0018 0.001 0.0047
Echinococcus multilocularis citrate lyase subunit beta protein 0.0024 0.0055 0.0056
Echinococcus multilocularis N acetylglucosaminyl phosphatidylinositol 0.0047 0.0216 0.0221
Onchocerca volvulus Heterochromatin protein 1 homolog 0.0042 0.0178 0.0443
Echinococcus multilocularis inositol monophosphatase 1 0.0038 0.0151 0.0155
Echinococcus multilocularis muscleblind protein 0.0301 0.2022 0.207
Brugia malayi hypothetical protein 0.0031 0.0103 0.0265
Trypanosoma brucei superoxide dismutase, putative 0.0039 0.0157 0.1117
Trypanosoma brucei Phosphatidylinositol 3-kinase tor1 0.0018 0.001 0.0047
Loa Loa (eye worm) hypothetical protein 0.0025 0.0062 0.0158
Trichomonas vaginalis chromodomain-helicase-DNA-binding protein, putative 0.0024 0.0056 0.0081
Echinococcus multilocularis Nuclear hormone receptor HR96 0.0028 0.008 0.0081
Brugia malayi hypothetical protein 0.0122 0.0746 0.1913
Echinococcus granulosus mitogen activated protein kinase 0.0053 0.0255 0.0261
Brugia malayi Niemann-Pick C1 protein precursor 0.0098 0.0576 0.1478
Echinococcus multilocularis expressed conserved protein 0.0092 0.0534 0.0547
Mycobacterium ulcerans class a beta-lactamase, BlaC 0.0132 0.0817 0.0797
Leishmania major pyruvate kinase 0.0067 0.036 0.2554
Entamoeba histolytica Niemann-Pick C1 protein, putative 0.0098 0.0576 0.1396
Echinococcus multilocularis transfer RNA-Lys 0.0037 0.0144 0.0148
Onchocerca volvulus 0.0032 0.0109 0.0229
Loa Loa (eye worm) phosphatidylinositol 3 0.0018 0.001 0.0025
Brugia malayi Superoxide dismutase, mitochondrial precursor, putative 0.0068 0.0367 0.0941
Trypanosoma cruzi ubiquitin carboxyl-terminal hydrolase, putative 0.0041 0.0173 0.1232
Echinococcus multilocularis lamin dm0 0.0054 0.0269 0.0275
Loa Loa (eye worm) hypothetical protein 0.006 0.031 0.0794
Trypanosoma cruzi hypothetical protein, conserved 0.0037 0.0144 0.1023
Trypanosoma cruzi glyceraldehyde 3-phosphate dehydrogenase, cytosolic, putative 0.007 0.0376 0.2703
Trichomonas vaginalis glyceraldehyde 3-phosphate dehydrogenase, putative 0.007 0.0376 0.0599
Loa Loa (eye worm) hypothetical protein 0.0051 0.0243 0.0624
Chlamydia trachomatis ferredoxin 0.0029 0.0085 0.1479
Mycobacterium tuberculosis Probable carbon monoxyde dehydrogenase (large chain) 0.0419 0.2854 0.2936
Mycobacterium tuberculosis Class a beta-lactamase BlaC 0.0132 0.0817 0.0824
Echinococcus multilocularis tumor protein p63 0.0682 0.4721 0.4835
Toxoplasma gondii inositol(myo)-1(or 4)-monophosphatase 2, putative 0.0038 0.0151 0.1903
Plasmodium falciparum glutathione reductase 0.0035 0.0134 0.1952
Brugia malayi Hypothetical 52.5 kDa protein ZK945.1 in chromosome II, putative 0.0037 0.0144 0.037
Mycobacterium ulcerans mycothiol conjugate amidase Mca 0.1425 1 1
Loa Loa (eye worm) hypothetical protein 0.0031 0.0103 0.0265
Plasmodium falciparum adrenodoxin-type ferredoxin, putative 0.0029 0.0085 0.1125
Trichomonas vaginalis CAMK family protein kinase 0.0094 0.0551 0.0883
Onchocerca volvulus 0.0037 0.0144 0.0338
Schistosoma mansoni hypothetical protein 0.004 0.0169 0.0173
Trichomonas vaginalis Citrate lyase beta chain, putative 0.0024 0.0055 0.0079
Trichomonas vaginalis PIKK family atypical protein kinase 0.0018 0.001 0.0006
Echinococcus multilocularis lipoxygenase domain containing protein 0.0023 0.0044 0.0045
Loa Loa (eye worm) pre-SET domain-containing protein family protein 0.0421 0.2872 0.7367
Echinococcus multilocularis Adrenodoxin, mitochondrial 0.0029 0.0085 0.0087
Mycobacterium tuberculosis NAD(P)H quinone reductase LpdA 0.0118 0.0717 0.072
Loa Loa (eye worm) pyruvate kinase 0.0067 0.036 0.0924
Trypanosoma cruzi dihydrolipoamide dehydrogenase, putative 0.0035 0.0134 0.0946
Echinococcus granulosus sterol regulatory element binding protein 0.0042 0.018 0.0184
Onchocerca volvulus Steroid hormone receptor family member cnr14 homolog 0.0059 0.03 0.0819
Schistosoma mansoni lipoxygenase 0.0095 0.0557 0.057
Trypanosoma cruzi glyceraldehyde 3-phosphate dehydrogenase, putative 0.007 0.0376 0.2703
Schistosoma mansoni survival motor neuron protein 0.0049 0.0233 0.0239
Loa Loa (eye worm) hypothetical protein 0.0046 0.0206 0.0527
Brugia malayi nuclear receptor NHR-67 0.0028 0.008 0.0204
Leishmania major acetoin dehydrogenase e3 component-like protein 0.0035 0.0134 0.0903
Mycobacterium tuberculosis Superoxide dismutase [FE] SodA 0.0068 0.0367 0.0357
Schistosoma mansoni ecdysone-induced protein 78c (dr-78) 0.0031 0.0103 0.0106
Trypanosoma cruzi phosphatidylinositol 3-related kinase, putative 0.0018 0.001 0.0047
Mycobacterium tuberculosis Possible oxygenase 0.0029 0.0085 0.0065
Schistosoma mansoni nuclear hormone receptor 0.0059 0.03 0.0308
Loa Loa (eye worm) fructose-bisphosphate aldolase 1 0.0093 0.0543 0.1393
Loa Loa (eye worm) hypothetical protein 0.0059 0.03 0.0771
Echinococcus granulosus Polycystic kidney disease protein 0.0023 0.0044 0.0045
Echinococcus multilocularis dihydrolipoamide dehydrogenase 0.0035 0.0134 0.0137
Trichomonas vaginalis superoxide dismutase [mn], putative 0.0068 0.0367 0.0584
Echinococcus granulosus fructose 16 bisphosphate aldolase 0.0093 0.0543 0.0556
Echinococcus multilocularis zinc finger protein 0.0023 0.0048 0.0049
Schistosoma mansoni nuclear receptor nhr-48 0.0028 0.008 0.0081
Loa Loa (eye worm) hypothetical protein 0.0021 0.0034 0.0088
Trypanosoma brucei glyceraldehyde 3-phosphate dehydrogenase, cytosolic 0.007 0.0376 0.2703
Echinococcus granulosus neuropeptide receptor A26 0.0459 0.3141 0.3216
Trypanosoma cruzi glyceraldehyde 3-phosphate dehydrogenase, putative 0.0022 0.0035 0.0231
Schistosoma mansoni hypothetical protein 0.0023 0.0044 0.0045
Loa Loa (eye worm) nuclear hormone receptor family member nhr-49 0.0059 0.03 0.0771
Mycobacterium ulcerans flavin-containing monoamine oxidase AofH 0.0304 0.2042 0.2024
Loa Loa (eye worm) ImpB/MucB/SamB family protein 0.002 0.0023 0.0058
Plasmodium falciparum thioredoxin reductase 0.0102 0.0607 1
Mycobacterium tuberculosis Probable reductase 0.0092 0.0533 0.0529
Brugia malayi MAP kinase sur-1 0.0053 0.0255 0.0654
Plasmodium falciparum ataxin-2 like protein, putative 0.0051 0.0243 0.3815
Loa Loa (eye worm) glyceraldehyde-3-phosphate dehydrogenase 0.0048 0.0223 0.0572
Leishmania major DNA polymerase kappa, putative 0.002 0.0023 0.0094
Loa Loa (eye worm) hypothetical protein 0.0037 0.0144 0.037
Chlamydia trachomatis Na(+)-translocating NADH-quinone reductase subunit F 0.0029 0.0085 0.1479
Leishmania major adrenodoxin-like protein,ferredoxin, 2fe-2s-like protein 0.0029 0.0085 0.0548
Brugia malayi Pyruvate kinase, alpha/beta domain containing protein 0.002 0.0027 0.0069
Trichomonas vaginalis PIKK family atypical protein kinase 0.0018 0.001 0.0006
Loa Loa (eye worm) hypothetical protein 0.0021 0.0034 0.0088
Mycobacterium tuberculosis Probable conserved lipoprotein LpqF 0.0063 0.0331 0.032
Trichomonas vaginalis conserved hypothetical protein 0.0027 0.0077 0.0115
Loa Loa (eye worm) hypothetical protein 0.0031 0.0103 0.0265
Schistosoma mansoni hypothetical protein 0.004 0.0169 0.0173
Trichomonas vaginalis Ferredoxin 3 0.0029 0.0085 0.0128
Schistosoma mansoni retinoid-x-receptor (RXR) 0.0031 0.0103 0.0106
Trypanosoma cruzi DNA polymerase kappa, putative 0.002 0.0023 0.0141
Echinococcus multilocularis pyruvate kinase 0.0053 0.0259 0.0266
Trypanosoma cruzi glyceraldehyde 3-phosphate dehydrogenase, putative 0.007 0.0376 0.2703
Brugia malayi hypothetical protein 0.0021 0.0034 0.0088
Echinococcus multilocularis histone lysine N methyltransferase MLL3 0.002 0.0025 0.0026
Brugia malayi PHD-finger family protein 0.0029 0.0087 0.0223
Trypanosoma brucei DNA polymerase IV, putative 0.002 0.0023 0.0141
Schistosoma mansoni chromobox protein 0.0069 0.0373 0.0382
Leishmania major phosphopantetheinyl transferase-like protein 0.0023 0.0047 0.0272
Mycobacterium ulcerans protoporphyrinogen oxidase 0.0021 0.0034 0.0012
Plasmodium vivax multidomain scavenger receptor, putative 0.0023 0.0044 0.0161
Schistosoma mansoni pyruvate kinase 0.0067 0.036 0.0369
Echinococcus granulosus abhydrolase domain containing protein 0.0039 0.0158 0.0161
Loa Loa (eye worm) hypothetical protein 0.0107 0.0642 0.1646
Echinococcus granulosus neuropeptide s receptor 0.0459 0.3141 0.3216
Schistosoma mansoni photoreceptor-specific nuclear receptor related 0.0059 0.03 0.0308
Loa Loa (eye worm) intermediate filament tail domain-containing protein 0.0054 0.0269 0.0689
Loa Loa (eye worm) hypothetical protein 0.0167 0.107 0.2744
Loa Loa (eye worm) abnormal chemotaxis protein 14 0.0042 0.018 0.0462
Toxoplasma gondii 4'-phosphopantetheinyl transferase domain-containing protein 0.0023 0.0047 0.0503
Trichomonas vaginalis PIKK family atypical protein kinase 0.0018 0.001 0.0006
Echinococcus granulosus serine:threonine protein kinase PLK1 0.0094 0.0551 0.0565
Trypanosoma brucei phosphatidylinositol 3-kinase, putative 0.0018 0.001 0.0047
Trichomonas vaginalis Ferredoxin 4 0.0029 0.0085 0.0128
Brugia malayi Nuclear hormone receptor family member nhr-31 0.0059 0.03 0.0771
Echinococcus granulosus intermediate filament protein 0.0054 0.0269 0.0275
Loa Loa (eye worm) hypothetical protein 0.0028 0.008 0.0204
Loa Loa (eye worm) hypothetical protein 0.0021 0.0034 0.0088
Trichomonas vaginalis PIKK family atypical protein kinase 0.0018 0.001 0.0006
Schistosoma mansoni family S12 unassigned peptidase (S12 family) 0.0037 0.0144 0.0148
Leishmania major fructose-1,6-bisphosphate aldolase 0.0093 0.0543 0.3889
Mycobacterium ulcerans N-acetyl-1-D-myo-inosityl-2-amino-2-deoxy-alpha-D-glucopyranoside deacetylase MshB 0.0047 0.0216 0.0194
Echinococcus multilocularis cadherin EGF LAG seven pass G type receptor 0.0019 0.0018 0.0018
Brugia malayi serine/threonine-protein kinase plk-2 0.0094 0.0551 0.1414
Trichomonas vaginalis CAMK family protein kinase 0.0094 0.0551 0.0883
Echinococcus granulosus nuclear receptor 2DBD gamma 0.0059 0.03 0.0308
Trypanosoma cruzi hypothetical protein, conserved 0.0211 0.1381 1
Toxoplasma gondii fructose-bisphosphate aldolase, putative 0.0093 0.0543 0.7187
Echinococcus multilocularis neuropeptide s receptor 0.0459 0.3141 0.3216
Echinococcus multilocularis methyl CpG binding domain protein 2 0.0017 0.0006 0.0007
Onchocerca volvulus Huntingtin homolog 0.0122 0.0746 0.2189
Loa Loa (eye worm) indoleamine 2,3-dioxygenase 0.0566 0.3898 1
Echinococcus multilocularis manganese superoxide dismutase 0.0068 0.0367 0.0376
Loa Loa (eye worm) hypoxia-induced factor 1 0.0154 0.0978 0.2508
Trypanosoma cruzi N-Acetyl-D-glucosaminylphosphatidylinositol de-N-acetylase, putative 0.0047 0.0216 0.1545
Loa Loa (eye worm) hypothetical protein 0.0116 0.0706 0.1811
Mycobacterium ulcerans electron transfer protein 0.0029 0.0085 0.0062
Mycobacterium ulcerans carbon monoxyde dehydrogenase large chain CoxL 0.0263 0.175 0.1732
Echinococcus multilocularis Nuclear hormone receptor HR96 0.0028 0.008 0.0081
Echinococcus granulosus Adrenodoxin mitochondrial 0.0029 0.0085 0.0087
Brugia malayi hypothetical protein 0.0023 0.0044 0.0112
Echinococcus multilocularis ferredoxin adrenodoxin 0.0029 0.0085 0.0087
Trypanosoma brucei phosphatidylinositol 3-related kinase, putative 0.0018 0.001 0.0047
Echinococcus multilocularis FTZ F1 alpha 0.0059 0.03 0.0308
Trypanosoma brucei N-acetyl-D-glucosaminylphosphatidylinositol de-N-acetylase 0.0047 0.0216 0.1545
Trichomonas vaginalis glyceraldehyde 3-phosphate dehydrogenase, putative 0.007 0.0376 0.0599
Loa Loa (eye worm) hypothetical protein 0.003 0.0098 0.0252
Mycobacterium tuberculosis Probable pyruvate kinase PykA 0.0067 0.036 0.035
Echinococcus granulosus L aminoadipate semialdehyde 0.0083 0.0468 0.0479
Echinococcus multilocularis aldehyde dehydrogenase, mitochondrial 0.0122 0.0752 0.077
Chlamydia trachomatis glyceraldehyde-3-phosphate dehydrogenase 0.007 0.0376 1
Loa Loa (eye worm) glyceraldehyde 3-phosphate dehydrogenase 0.0046 0.0206 0.0527
Loa Loa (eye worm) hypothetical protein 0.0021 0.0033 0.0084
Trichomonas vaginalis mercuric reductase, putative 0.0035 0.0134 0.0207
Echinococcus multilocularis nuclear receptor nhr 48 0.0028 0.008 0.0081
Schistosoma mansoni lamin 0.0054 0.0269 0.0275
Echinococcus granulosus pyruvate kinase 0.0035 0.0128 0.0131
Plasmodium vivax hypothetical protein, conserved 0.0037 0.0144 0.1916
Loa Loa (eye worm) beta-LACTamase domain containing family member 0.0037 0.0144 0.037
Schistosoma mansoni intermediate filament proteins 0.0054 0.0269 0.0275
Giardia lamblia Ubiquitin carboxyl-terminal hydrolase 4 0.0041 0.0173 0.0402
Schistosoma mansoni ubiquitin-specific peptidase 8 (C19 family) 0.0041 0.0173 0.0177
Toxoplasma gondii ferredoxin, putative 0.0029 0.0085 0.1013
Brugia malayi tailless protein 0.0028 0.008 0.0204
Trichomonas vaginalis glyceraldehyde 3-phosphate dehydrogenase, putative 0.0046 0.0206 0.0323
Brugia malayi cytoplasmic intermediate filament protein 0.0029 0.0089 0.0229
Loa Loa (eye worm) hydrolase 0.0039 0.0158 0.0404
Brugia malayi PAS domain containing protein 0.005 0.0236 0.0606
Echinococcus multilocularis pyruvate kinase 0.0035 0.0128 0.0131
Brugia malayi nuclear receptor NHR-88 0.0059 0.03 0.0771
Echinococcus multilocularis FKBP12 rapamycin complex associated protein 0.0018 0.001 0.001
Schistosoma mansoni serine/threonine protein kinase 0.0053 0.0255 0.0261
Loa Loa (eye worm) hypothetical protein 0.0025 0.0062 0.0158
Toxoplasma gondii CMGC kinase, MAPK family (ERK) MAPK-1 0.0053 0.0255 0.3307
Echinococcus multilocularis RUN 0.0023 0.0044 0.0045
Loa Loa (eye worm) beta-lactamase 0.0037 0.0144 0.037
Brugia malayi Pyruvate kinase, muscle isozyme 0.0067 0.036 0.0924
Loa Loa (eye worm) nuclear hormone receptor family member nhr-41 0.0059 0.03 0.0771
Trypanosoma cruzi superoxide dismutase, putative 0.0039 0.0157 0.1117
Loa Loa (eye worm) hypothetical protein 0.0059 0.03 0.0771
Leishmania major mitogen activated protein kinase, putative,map kinase, putative 0.0053 0.0255 0.1789
Echinococcus granulosus terminal deoxycytidyl transferase rev1 0.002 0.0023 0.0023
Loa Loa (eye worm) hypothetical protein 0.0079 0.0443 0.1136
Schistosoma mansoni tar DNA-binding protein 0.0065 0.0343 0.0351
Loa Loa (eye worm) hypothetical protein 0.0028 0.008 0.0204
Echinococcus granulosus RUN 0.0023 0.0044 0.0045
Echinococcus granulosus bromodomain adjacent to zinc finger domain 0.0064 0.034 0.0348
Echinococcus granulosus zinc finger protein 0.0023 0.0048 0.0049
Schistosoma mansoni thyroid hormone receptor 0.0184 0.1188 0.1216
Echinococcus granulosus histone lysine methyltransferase setb 0.0079 0.0443 0.0454
Brugia malayi hypothetical protein 0.0242 0.1602 0.4111
Leishmania major adrenodoxin-like protein,ferredoxin, 2fe-2s-like protein 0.0029 0.0085 0.0548
Loa Loa (eye worm) cytoplasmic intermediate filament protein 0.0029 0.0089 0.0229
Brugia malayi Inositol-1 0.0038 0.0151 0.0387
Trypanosoma brucei beta lactamase 0.0063 0.0331 0.2379
Trichomonas vaginalis D-aminoacylase, putative 0.0037 0.0144 0.0224
Loa Loa (eye worm) hypothetical protein 0.0028 0.008 0.0204
Echinococcus granulosus inositol monophosphatase 1 0.0038 0.0151 0.0155
Schistosoma mansoni hypothetical protein 0.0021 0.0032 0.0033
Onchocerca volvulus 0.0049 0.0233 0.0612
Loa Loa (eye worm) pyruvate kinase 0.0067 0.036 0.0924
Mycobacterium tuberculosis Dihydrolipoamide dehydrogenase LpdC (lipoamide reductase (NADH)) (lipoyl dehydrogenase) (dihydrolipoyl dehydrogenase) (diaphoras 0.0118 0.0717 0.072
Mycobacterium ulcerans dihydrolipoamide dehydrogenase, LpdB 0.0035 0.0134 0.0111
Loa Loa (eye worm) fructose-bisphosphate aldolase 2 0.0093 0.0543 0.1393
Onchocerca volvulus 0.0023 0.0044 0.0028
Brugia malayi Nuclear hormone receptor family member nhr-14 0.0059 0.03 0.0771
Leishmania major superoxide dismutase, putative 0.0039 0.0157 0.1075
Mycobacterium tuberculosis Probable glyceraldehyde 3-phosphate dehydrogenase Gap (GAPDH) 0.0024 0.0053 0.0031
Brugia malayi Nuclear hormone receptor family member nhr-25 0.0059 0.03 0.0771
Echinococcus granulosus tumor protein p63 0.0682 0.4721 0.4835
Brugia malayi latrophilin 2 splice variant baaae 0.0041 0.0174 0.0448
Schistosoma mansoni hypothetical protein 0.0043 0.0191 0.0195
Loa Loa (eye worm) hypothetical protein 0.0028 0.008 0.0204
Schistosoma mansoni Protoporphyrinogen oxidase chloroplast/mitochondrial precursor 0.0021 0.0034 0.0035
Schistosoma mansoni fructose 16-bisphosphate aldolase 0.0093 0.0543 0.0556
Trichomonas vaginalis DNA helicase recq, putative 0.0022 0.0038 0.0051
Echinococcus multilocularis dna polymerase kappa 0.002 0.0023 0.0023
Trypanosoma brucei dihydrolipoamide dehydrogenase, point mutation 0.0035 0.0134 0.0946
Mycobacterium tuberculosis Possible conserved lipoprotein LpqK 0.0037 0.0144 0.0126
Trypanosoma brucei mitogen activated protein kinase 4, putative 0.0053 0.0255 0.1827
Trichomonas vaginalis fructose-bisphosphate aldolase, putative 0.059 0.4068 0.6574
Mycobacterium ulcerans hypothetical protein 0.0144 0.0907 0.0886
Toxoplasma gondii histone lysine-specific demethylase 0.0021 0.0034 0.0333
Echinococcus granulosus diuretic hormone 44 receptor GPRdih2 0.0019 0.0018 0.0018
Entamoeba histolytica glyceraldehyde-3-phosphate dehydrogenase, putative 0.007 0.0376 0.0902
Echinococcus multilocularis pyruvate kinase 0.0035 0.0128 0.0131
Mycobacterium ulcerans aldehyde dehydrogenase 0.0122 0.0752 0.0731
Mycobacterium ulcerans monoamine oxidase 0.0021 0.0034 0.0012
Loa Loa (eye worm) hypothetical protein 0.0039 0.0161 0.0414
Brugia malayi nuclear receptor RXR 0.0031 0.0103 0.0265
Trichomonas vaginalis Clan CA, family C19, ubiquitin hydrolase-like cysteine peptidase 0.0041 0.0173 0.0271
Entamoeba histolytica N-acetylglucosaminyl-phosphatidylinositol de-N-acetylase, putative 0.0047 0.0216 0.0509
Brugia malayi nuclear receptor RXR 0.0028 0.008 0.0204
Brugia malayi chromobox protein homolog 3 0.0039 0.0158 0.0404
Giardia lamblia Glyceraldehyde 3-phosphate dehydrogenase 0.0046 0.0205 0.0482
Mycobacterium tuberculosis Conserved protein 0.0037 0.0144 0.0126
Trichomonas vaginalis chromodomain-helicase-DNA-binding protein, putative 0.0018 0.0013 0.0011
Loa Loa (eye worm) hypothetical protein 0.0041 0.0173 0.0444
Mycobacterium leprae Probable pyruvate kinase PykA 0.0067 0.036 0.0327
Loa Loa (eye worm) hypothetical protein 0.0021 0.0034 0.0088
Entamoeba histolytica deoxycytidyl transferase, putative 0.002 0.0023 0.0032
Schistosoma mansoni fructose 16-bisphosphate aldolase 0.0093 0.0543 0.0556
Brugia malayi indoleamine 2,3-dioxygenase 0.0566 0.3898 1
Mycobacterium tuberculosis Conserved hypothetical protein 0.0047 0.0216 0.0201
Trypanosoma brucei glyceraldehyde 3-phosphate dehydrogenase, glycosomal 0.007 0.0376 0.2703
Echinococcus multilocularis Niemann Pick C1 protein 0.0098 0.0576 0.059
Schistosoma mansoni Tr4/Tr2 (homologue) 0.0059 0.03 0.0308
Echinococcus multilocularis chromobox protein 1 0.0069 0.0373 0.0382
Trypanosoma cruzi iron superoxide dismutase, putative 0.0068 0.0367 0.2639
Trichomonas vaginalis PIKK family atypical protein kinase 0.0018 0.001 0.0006
Brugia malayi amine oxidase, flavin-containing family protein 0.0021 0.0034 0.0088
Schistosoma mansoni steroid hormone receptor ad4bp 0.0059 0.03 0.0308
Echinococcus granulosus fructose bisphosphate aldolase class I 0.0093 0.0543 0.0556
Loa Loa (eye worm) PLK/PLK1 protein kinase 0.0094 0.0551 0.1414
Echinococcus multilocularis serine:threonine protein kinase PLK1 0.0094 0.0551 0.0565
Echinococcus granulosus Nuclear hormone receptor HR96 0.0028 0.008 0.0081
Entamoeba histolytica rodhanase-like domain containing protein 0.0116 0.0706 0.1715
Brugia malayi Nuclear hormone receptor family member nhr-41 0.0059 0.03 0.0771
Schistosoma mansoni loxhd1 0.0023 0.0044 0.0045
Loa Loa (eye worm) hypothetical protein 0.0122 0.0746 0.1913
Trichomonas vaginalis PIKK family atypical protein kinase 0.0018 0.001 0.0006
Loa Loa (eye worm) thioredoxin reductase 0.0102 0.0607 0.1558
Trypanosoma cruzi phosphatidylinositol kinase related protein, putative 0.0018 0.001 0.0049
Trichomonas vaginalis glyceraldehyde 3-phosphate dehydrogenase, putative 0.007 0.0376 0.0599
Echinococcus multilocularis abhydrolase domain containing protein 0.0039 0.0158 0.0161
Onchocerca volvulus 0.0059 0.03 0.0819
Trichomonas vaginalis glyceraldehyde 3-phosphate dehydrogenase, putative 0.007 0.0376 0.0599
Onchocerca volvulus 0.0083 0.0468 0.1335
Plasmodium falciparum superoxide dismutase [Fe] 0.0068 0.0367 0.5915
Trichomonas vaginalis mitotic inducer phosphatase CDC25, putative 0.0116 0.0706 0.1133
Mycobacterium tuberculosis Putative ferredoxin reductase 0.0092 0.0533 0.0529
Schistosoma mansoni cpg binding protein 0.0063 0.0331 0.0339
Trichomonas vaginalis chromodomain helicase DNA binding protein, putative 0.0024 0.0056 0.0081
Echinococcus multilocularis pyruvate kinase 0.0067 0.036 0.0369
Onchocerca volvulus Pyruvate kinase homolog 0.0067 0.036 0.1002
Trichomonas vaginalis iron superoxide dismutase A, putative 0.0068 0.0367 0.0584
Giardia lamblia Pyruvate kinase 0.0035 0.0128 0.029
Mycobacterium leprae possible inositol monophosphatase SubH (IMPase) (inositol-1-phosphatase) (I-1-Pase ). 0.0034 0.0123 0.0089
Trypanosoma cruzi iron superoxide dismutase A, mitochondrial 0.0068 0.0367 0.2639
Loa Loa (eye worm) doublecortin family protein 0.0023 0.0044 0.0112
Trichomonas vaginalis D-aminoacylase, putative 0.0037 0.0144 0.0224
Loa Loa (eye worm) hypothetical protein 0.0301 0.2022 0.5186
Echinococcus granulosus lamin 0.0054 0.0269 0.0275
Echinococcus granulosus Basic leucine zipper bZIP transcription 0.0043 0.0191 0.0195
Echinococcus multilocularis lysine specific histone demethylase 1A 0.0021 0.0034 0.0035
Toxoplasma gondii histone lysine methyltransferase SET/SUV39 0.0061 0.0319 0.4164
Onchocerca volvulus 0.0028 0.008 0.0139
Echinococcus multilocularis geminin 0.0342 0.2309 0.2365
Schistosoma mansoni hypothetical protein 0.0019 0.0018 0.0018
Toxoplasma gondii superoxide dismutase 0.0068 0.0367 0.4813
Trypanosoma brucei DNA polymerase kappa, putative 0.002 0.0023 0.0141
Mycobacterium ulcerans flavodoxin reductase Hmp 0.0029 0.0085 0.0062
Echinococcus multilocularis pyruvate kinase 0.0067 0.036 0.0369
Echinococcus granulosus Nuclear hormone receptor family member nhr 41 0.0059 0.03 0.0308
Loa Loa (eye worm) hypothetical protein 0.0059 0.03 0.0771
Brugia malayi calcium-independent alpha-latrotoxin receptor 2, putative 0.0019 0.0018 0.0045
Trichomonas vaginalis glucosamine-6-phosphate isomerase, putative 0.0047 0.0216 0.034
Echinococcus granulosus geminin 0.0342 0.2309 0.2365
Trichomonas vaginalis PIKK family atypical protein kinase 0.0018 0.001 0.0006
Schistosoma mansoni histone-lysine n-methyltransferase setb1 0.0079 0.0443 0.0454
Mycobacterium ulcerans phosphopantetheinyl transferase, PptII 0.0023 0.0047 0.0024
Echinococcus multilocularis survival motor neuron protein 1 0.0242 0.1602 0.1641
Echinococcus granulosus serine protein kinase ATM 0.0025 0.0057 0.0059
Schistosoma mansoni aldehyde dehydrogenase 0.0122 0.0752 0.077
Loa Loa (eye worm) bromodomain containing protein 0.0018 0.0011 0.0028
Trypanosoma cruzi glyceraldehyde-3-phosphate dehydrogenase, putative 0.0046 0.0205 0.1466
Trypanosoma cruzi phosphatidylinositol kinase related protein, putative 0.0021 0.0033 0.0214
Loa Loa (eye worm) hypothetical protein 0.0042 0.0179 0.0458
Brugia malayi SWIRM domain containing protein 0.0021 0.0034 0.0088
Plasmodium falciparum holo-[acyl-carrier-protein] synthase, putative 0.0023 0.0047 0.0482
Mycobacterium tuberculosis Possible electron transfer protein FdxB 0.0029 0.0085 0.0065
Schistosoma mansoni zinc finger protein 0.0028 0.008 0.0081
Trypanosoma brucei iron superoxide dismutase A, mitochondrial 0.0068 0.0367 0.2639
Schistosoma mansoni hypothetical protein 0.0019 0.0018 0.0018
Schistosoma mansoni aryl hydrocarbon receptor 0.005 0.0236 0.0242
Echinococcus granulosus Nuclear hormone receptor HR96 0.0028 0.008 0.0081
Leishmania major DNA polymerase eta, putative 0.002 0.0023 0.0094
Onchocerca volvulus 0.0037 0.0144 0.0338
Mycobacterium ulcerans aerobic-type carbon monoxide dehydrogenase subunit CoxL_2 0.0419 0.2854 0.2838
Loa Loa (eye worm) hypothetical protein 0.0023 0.0044 0.0112
Trypanosoma brucei PAB1-binding protein , putative 0.0051 0.0243 0.1741
Trichomonas vaginalis conserved hypothetical protein 0.0039 0.0158 0.0245
Echinococcus multilocularis Peptidase C19, ubiquitin carboxyl terminal hydrolase 2 0.0041 0.0173 0.0177
Brugia malayi hypothetical protein 0.0023 0.0044 0.0112
Schistosoma mansoni tar DNA-binding protein 0.0065 0.0343 0.0351
Mycobacterium ulcerans esterase/lipase LipP 0.0037 0.0144 0.0122
Echinococcus granulosus glyceraldehyde 3 phosphate dehydrogenase 0.007 0.0376 0.0385
Trypanosoma cruzi hypothetical protein, conserved 0.0211 0.1381 1
Brugia malayi Rhodanese-like domain containing protein 0.0116 0.0706 0.1811
Trichomonas vaginalis CMGC family protein kinase 0.0053 0.0255 0.0403
Echinococcus granulosus hepatocyte nuclear factor 4 alpha 0.0059 0.03 0.0308
Wolbachia endosymbiont of Brugia malayi dihydrolipoamide dehydrogenase E3 component 0.0035 0.0134 0.2632
Schistosoma mansoni phosphatidylinositol 3-and 4-kinase 0.0018 0.001 0.001
Leishmania major hypothetical protein, conserved 0.0029 0.0085 0.0548
Toxoplasma gondii glyceraldehyde-3-phosphate dehydrogenase GAPDH1 0.007 0.0376 0.4932
Brugia malayi Glyceraldehyde 3-phosphate dehydrogenase 0.007 0.0376 0.0964
Brugia malayi Nuclear hormone receptor family member nhr-19 0.0059 0.03 0.0771
Echinococcus granulosus dihydrolipoamide dehydrogenase 0.0035 0.0134 0.0137
Loa Loa (eye worm) DR-78 0.0028 0.008 0.0204
Echinococcus granulosus Mitotic checkpoint protein PRCC C terminal 0.0125 0.0769 0.0788
Toxoplasma gondii ABC1 family protein 0.0037 0.0144 0.1812
Schistosoma mansoni ataxia telangiectasia mutated (atm) 0.0025 0.0057 0.0059
Trichomonas vaginalis PIKK family atypical protein kinase 0.0018 0.001 0.0006
Mycobacterium ulcerans carbon monoxyde dehydrogenase large chain CoxL 0.0419 0.2854 0.2838
Loa Loa (eye worm) hypothetical protein 0.0051 0.0247 0.0634
Brugia malayi Pre-SET motif family protein 0.0061 0.0319 0.0818
Echinococcus multilocularis microtubule associated protein 2 0.1392 0.9765 1
Wolbachia endosymbiont of Brugia malayi superoxide dismutase, SodA 0.0068 0.0367 0.9732
Brugia malayi dihydrolipoyl dehydrogenase, mitochondrial precursor, putative 0.0035 0.0134 0.0343
Plasmodium vivax N-acetylglucosaminylphosphatidylinositol deacetylase, putative 0.0047 0.0216 0.3171
Trypanosoma brucei dihydrolipoyl dehydrogenase 0.0035 0.0134 0.0946
Leishmania major N-acetyl-D-acetylglucosaminylphosphatidylinositol deacetylase 0.0047 0.0216 0.1505
Toxoplasma gondii pyruvate dehydrogenase complex subunit PDH-E3II 0.0035 0.0134 0.1669
Loa Loa (eye worm) hypothetical protein 0.0017 0.0006 0.0016
Schistosoma mansoni superoxide dismutase [mn] 0.0068 0.0367 0.0376
Echinococcus granulosus nuclear receptor nhr 48 0.0028 0.008 0.0081
Schistosoma mansoni ubiquitin-specific peptidase 2 (C19 family) 0.0041 0.0173 0.0177
Trypanosoma brucei DNA polymerase IV, putative 0.002 0.0023 0.0141
Brugia malayi CHE-14 protein 0.0042 0.018 0.0462
Onchocerca volvulus Superoxide dismutase [Mn], mitochondrial homolog 0.0068 0.0367 0.1023
Onchocerca volvulus Nuclear receptor subfamily 6 group A member 1 homolog 0.0028 0.008 0.0139
Brugia malayi fructose-bisphosphate aldolase 2 0.0093 0.0543 0.1393
Echinococcus granulosus lamin dm0 0.0054 0.0269 0.0275
Trypanosoma cruzi hypothetical protein, conserved 0.0037 0.0144 0.1023
Mycobacterium tuberculosis Probable dehydrogenase 0.0092 0.0533 0.0529
Loa Loa (eye worm) hypothetical protein 0.0037 0.0144 0.037
Trichomonas vaginalis chromobox protein, putative 0.0069 0.0373 0.0595
Trypanosoma cruzi mitogen-activated protein kinase 11, putative 0.0053 0.0255 0.1827
Entamoeba histolytica hypothetical protein 0.0043 0.0191 0.0446
Trichomonas vaginalis Clan CA, family C19, ubiquitin hydrolase-like cysteine peptidase 0.0041 0.0173 0.0271
Echinococcus multilocularis Ataxin 2, N terminal,domain containing protein 0.0023 0.0044 0.0045
Trypanosoma cruzi iron superoxide dismutase, putative 0.0068 0.0367 0.2639
Brugia malayi Rhodanese-like domain containing protein 0.0116 0.0706 0.1811
Brugia malayi Nuclear hormone receptor-like 1 0.0059 0.03 0.0771
Schistosoma mansoni aldehyde dehydrogenase 0.0122 0.0752 0.077
Brugia malayi 2Fe-2S iron-sulfur cluster binding domain containing protein 0.0029 0.0085 0.0218
Trichomonas vaginalis superoxide dismutase [fe], putative 0.0068 0.0367 0.0584
Wolbachia endosymbiont of Brugia malayi glyceraldehyde-3-phosphate dehydrogenase, GapA 0.007 0.0376 1
Trypanosoma cruzi fructose-bisphosphate aldolase, glycosomal, putative 0.0093 0.0543 0.3917
Loa Loa (eye worm) cytochrome P450 family protein 0.0054 0.0263 0.0674
Schistosoma mansoni retinoic acid receptor RXR 0.0059 0.03 0.0308
Loa Loa (eye worm) hypothetical protein 0.0037 0.0144 0.037
Toxoplasma gondii LsmAD domain-containing protein 0.0051 0.0243 0.3147
Mycobacterium ulcerans dehydrogenase 0.0021 0.0034 0.0012
Trypanosoma cruzi glyceraldehyde 3-phosphate dehydrogenase, cytosolic, putative 0.0022 0.0035 0.0231
Echinococcus granulosus chromobox protein 1 0.0069 0.0373 0.0382
Schistosoma mansoni Lysine-specific histone demethylase 1 0.0021 0.0034 0.0035
Mycobacterium ulcerans carbon monoxide dehydrogenase 0.0588 0.4057 0.4044
Schistosoma mansoni nuclear hormone receptor nor-1/nor-2 0.0059 0.03 0.0308
Trypanosoma cruzi dihydrolipoamide dehydrogenase, putative 0.0035 0.0134 0.0946
Toxoplasma gondii histone lysine-specific demethylase LSD1/BHC110/KDMA1A 0.0025 0.0059 0.067
Trichomonas vaginalis glyceraldehyde 3-phosphate dehydrogenase, putative 0.0024 0.0052 0.0075
Loa Loa (eye worm) hypothetical protein 0.0031 0.0103 0.0265
Trichomonas vaginalis Ferredoxin 7 0.0029 0.0085 0.0128
Trypanosoma cruzi DNA polymerase eta, putative 0.002 0.0023 0.0141
Giardia lamblia [2Fe-2S] ferredoxin 0.0029 0.0085 0.0185
Schistosoma mansoni zinc finger protein 0.0023 0.0048 0.0049
Mycobacterium tuberculosis Probable NADH dehydrogenase Ndh 0.0092 0.0533 0.0529
Trypanosoma brucei DNA polymerase kappa, putative 0.002 0.0023 0.0141
Trypanosoma cruzi PAB1-binding protein , putative 0.0051 0.0243 0.1741
Onchocerca volvulus Pyruvate kinase homolog 0.0067 0.036 0.1002
Echinococcus multilocularis nuclear receptor subfamily 1 group D 0.0031 0.0103 0.0106
Echinococcus multilocularis histone lysine methyltransferase setb histone lysine methyltransferase eggless 0.0079 0.0443 0.0454
Trypanosoma brucei iron superoxide dismutase C, mitochondrial 0.0039 0.0157 0.1117
Loa Loa (eye worm) hypothetical protein 0.0028 0.008 0.0204
Trichomonas vaginalis chromobox protein, putative 0.0069 0.0373 0.0595
Trypanosoma brucei glyceraldehyde 3-phosphate dehydrogenase, glycosomal 0.007 0.0376 0.2703
Schistosoma mansoni family S12 unassigned peptidase (S12 family) 0.0037 0.0144 0.0148
Brugia malayi Doublecortin family protein 0.0023 0.0044 0.0112
Trypanosoma cruzi 2,4-dihydroxyhept-2-ene-1,7-dioic acid aldolase, putative 0.0024 0.0055 0.0375
Brugia malayi CXXC zinc finger family protein 0.0058 0.0294 0.0753
Echinococcus multilocularis hepatocyte nuclear factor 4 alpha 0.0059 0.03 0.0308
Schistosoma mansoni chromobox protein 0.0069 0.0373 0.0382
Mycobacterium ulcerans dihydrolipoamide dehydrogenase 0.0035 0.0134 0.0111
Onchocerca volvulus 0.0054 0.0269 0.072
Mycobacterium ulcerans carbon monoxyde dehydrogenase small chain CoxS 0.0169 0.1086 0.1065
Mycobacterium tuberculosis Probable membrane NADH dehydrogenase NdhA 0.0092 0.0533 0.0529
Giardia lamblia Fructose-bisphosphate aldolase 0.059 0.4068 1
Trypanosoma cruzi glyceraldehyde 3-phosphate dehydrogenase, C-terminal domain, putative 0.0022 0.0035 0.0231
Trypanosoma brucei unspecified product 0.002 0.0023 0.0141
Echinococcus granulosus fructose 16 bisphosphate aldolase 0.0093 0.0543 0.0556
Trypanosoma cruzi dihydrolipoyl dehydrogenase, putative 0.0035 0.0134 0.0946
Echinococcus granulosus phosphatidylinositol 3 and 4 kinase 0.0018 0.001 0.001
Echinococcus multilocularis fructose 1,6 bisphosphate aldolase 0.0093 0.0543 0.0556
Mycobacterium tuberculosis Probable carbon monoxyde dehydrogenase (medium chain) 0.03 0.201 0.2061
Mycobacterium ulcerans aerobic-type carbon monoxide dehydrogenase subunit CoxM_2 0.03 0.201 0.1992
Schistosoma mansoni patched 1 0.0042 0.018 0.0184
Trypanosoma brucei phosphatidylinositol kinase related protein, putative 0.0025 0.0057 0.0392
Echinococcus multilocularis fructose bisphosphate aldolase class I 0.0093 0.0543 0.0556
Entamoeba histolytica serine/threonine protein kinase, putative 0.0094 0.0551 0.1334
Echinococcus granulosus bromodomain adjacent to zinc finger domain 0.0037 0.0144 0.0147
Echinococcus granulosus dna polymerase kappa 0.002 0.0023 0.0023
Echinococcus multilocularis lipoxygenase domain containing protein 0.0023 0.0044 0.0045
Trichomonas vaginalis esterase, putative 0.0037 0.0144 0.0224
Trichomonas vaginalis CAMK family protein kinase 0.0047 0.0215 0.0339
Trypanosoma cruzi pyruvate kinase 2, putative 0.0067 0.036 0.2589
Loa Loa (eye worm) nuclear hormone receptor family member nhr-40 0.0059 0.03 0.0771
Treponema pallidum quinoline 2-oxidoreductase 0.0141 0.0883 0.2079
Brugia malayi hydrolase, alpha/beta fold family protein 0.0039 0.0158 0.0404
Echinococcus multilocularis muscleblind protein 1 0.0301 0.2022 0.207
Loa Loa (eye worm) hypothetical protein 0.0059 0.03 0.0771
Onchocerca volvulus 0.0029 0.0085 0.0155
Trichomonas vaginalis fructose-bisphosphate aldolase, putative 0.059 0.4068 0.6574
Schistosoma mansoni nuclear receptor 2DBD-gamma 0.0059 0.03 0.0308
Trichomonas vaginalis chromodomain-helicase-DNA-binding protein, putative 0.0024 0.0056 0.0081
Echinococcus multilocularis arachidonate 5 lipoxygenase 0.0136 0.0848 0.0868
Schistosoma mansoni hypothetical protein 0.0566 0.3898 0.3992
Mycobacterium tuberculosis Mycothiol conjugate amidase Mca (mycothiol S-conjugate amidase) 0.1378 0.9666 1
Mycobacterium ulcerans beta-lactamase 0.0037 0.0144 0.0122
Trichomonas vaginalis xanthine dehydrogenase, putative 0.0888 0.6185 1
Trichomonas vaginalis DNA polymerase IV / kappa, putative 0.002 0.0023 0.0027
Echinococcus granulosus Peptidase C19 ubiquitin carboxyl terminal hydrolase 2 0.0041 0.0173 0.0177
Echinococcus granulosus citrate lyase subunit beta protein 0.0024 0.0055 0.0056
Trichomonas vaginalis Ferredoxin 2 0.0029 0.0085 0.0128
Echinococcus granulosus thyroid hormone receptor alpha 0.0028 0.008 0.0081
Trichomonas vaginalis chromodomain helicase DNA binding protein, putative 0.0024 0.0056 0.0081
Schistosoma mansoni retinoid-x-receptor (RXR) 0.0059 0.03 0.0308
Mycobacterium ulcerans citrate (pro-3S)-lyase subunit beta 0.0024 0.0055 0.0032
Schistosoma mansoni methyl-cpg binding protein mbd 0.0017 0.0006 0.0007
Trypanosoma cruzi 2,4-dihydroxyhept-2-ene-1,7-dioic acid aldolase, putative 0.0024 0.0055 0.0375
Echinococcus multilocularis Basic leucine zipper (bZIP) transcription 0.0043 0.0191 0.0195
Echinococcus granulosus microtubule associated protein 2 0.1392 0.9765 1
Trichomonas vaginalis superoxide dismutase [fe], putative 0.0068 0.0367 0.0584
Echinococcus granulosus FTZ F1 nuclear receptor protein 0.0059 0.03 0.0308
Echinococcus multilocularis protein patched 0.0042 0.018 0.0184
Schistosoma mansoni aminoadipate-semialdehyde dehydrogenase 0.0083 0.0468 0.0479
Leishmania major superoxide dismutase, putative 0.0039 0.0157 0.1075
Trichomonas vaginalis PIKK family atypical protein kinase 0.0018 0.001 0.0006
Trichomonas vaginalis cdc25b, putative 0.0116 0.0706 0.1133
Trichomonas vaginalis superoxide dismutase [fe], putative 0.0068 0.0367 0.0584
Mycobacterium ulcerans aldehyde dehydrogenase 0.0122 0.0752 0.0731
Mycobacterium ulcerans carbon monoxyde dehydrogenase medium chain CoxM 0.03 0.201 0.1992
Mycobacterium tuberculosis Conserved protein 0.0037 0.0144 0.0126
Echinococcus granulosus pyruvate kinase 0.0067 0.036 0.0369
Mycobacterium tuberculosis Conserved hypothetical protein 0.0021 0.0034 0.0012
Brugia malayi intermediate filament protein 0.0054 0.0269 0.0689
Trichomonas vaginalis chromodomain helicase DNA binding protein, putative 0.0024 0.0056 0.0081
Brugia malayi alpha keto acid dehydrogenase complex, E3 component, lipoamide dehydrogenase 0.0026 0.0067 0.0172
Trypanosoma cruzi dihydrolipoamide dehydrogenase, putative 0.0035 0.0134 0.0946
Echinococcus granulosus dnaJ subfamily B 0.0825 0.574 0.5878
Leishmania major iron superoxide dismutase, putative 0.0068 0.0367 0.2604
Schistosoma mansoni pyruvate kinase 0.0067 0.036 0.0369
Mycobacterium ulcerans oxidoreductase 0.0029 0.0085 0.0062
Mycobacterium ulcerans oxidoreductase 0.0029 0.0085 0.0062
Mycobacterium tuberculosis Probable lipase LipD 0.0037 0.0144 0.0126
Brugia malayi Pre-SET motif family protein 0.0421 0.2872 0.7367
Trypanosoma cruzi polo-like protein kinase, putative 0.0094 0.0551 0.3976
Loa Loa (eye worm) steroid hormone receptor 0.0059 0.03 0.0771
Trypanosoma cruzi trypanothione reductase, putative 0.0035 0.0134 0.0946
Echinococcus granulosus indoleamine 23 dioxygenase 2 0.0566 0.3898 0.3992
Loa Loa (eye worm) nuclear receptor nhr-7B 0.0028 0.008 0.0204
Entamoeba histolytica fructose-1,6-bisphosphate aldolase, putative 0.059 0.4068 1
Schistosoma mansoni cellular tumor antigen P53 0.01 0.0591 0.0605
Brugia malayi Nuclear hormone receptor family member nhr-40 0.0059 0.03 0.0771
Entamoeba histolytica ubiquitin carboxyl-terminal hydrolase domain containing protein 0.0041 0.0173 0.0402
Schistosoma mansoni serine/threonine protein kinase 0.0094 0.0551 0.0565
Echinococcus multilocularis cytoplasmic intermediate filament protein 0.0026 0.0069 0.007
Mycobacterium tuberculosis Possible oxidoreductase 0.0021 0.0034 0.0012
Echinococcus granulosus mitogen activated protein kinase 3 0.0053 0.0255 0.0261
Plasmodium falciparum ferredoxin, putative 0.0029 0.0085 0.1125
Loa Loa (eye worm) nuclear hormone receptor-like 1 0.0031 0.0103 0.0265
Brugia malayi ecdysteroid receptor 0.0059 0.03 0.0771
Schistosoma mansoni hypothetical protein 0.0125 0.0769 0.0788
Echinococcus multilocularis dnaJ subfamily B 0.0825 0.574 0.5878
Trypanosoma cruzi polo-like protein kinase, putative 0.0094 0.0551 0.3976
Trichomonas vaginalis D-aminoacylase, putative 0.0037 0.0144 0.0224
Brugia malayi hypoxia-induced factor 1 0.0154 0.0978 0.2508
Trypanosoma brucei phosphatidylinositol 4-kinase, putative 0.0018 0.001 0.0047
Trypanosoma cruzi mitogen activated protein kinase 2, putative 0.0053 0.0255 0.1827
Loa Loa (eye worm) hypothetical protein 0.0059 0.03 0.0771
Echinococcus granulosus lipoxygenase domain containing protein 0.0023 0.0044 0.0045
Loa Loa (eye worm) hypothetical protein 0.0116 0.0706 0.1811
Schistosoma mansoni methyl-cpg binding protein mbd 0.0017 0.0006 0.0007
Echinococcus granulosus thioredoxin glutathione reductase 0.0103 0.0611 0.0626
Trichomonas vaginalis conserved hypothetical protein 0.0018 0.0013 0.0011
Leishmania major aldehyde dehydrogenase, mitochondrial precursor 0.0122 0.0752 0.5411
Trypanosoma brucei DNA polymerase eta, putative 0.002 0.0023 0.0141
Mycobacterium ulcerans citrate lyase beta subunit, CitE_2 0.0024 0.0055 0.0032
Trypanosoma brucei DNA polymerase IV, putative 0.002 0.0023 0.0141
Schistosoma mansoni niemann-pick C1 (NPC1) 0.0099 0.0587 0.0601
Brugia malayi Bromodomain containing protein 0.008 0.0451 0.1158
Loa Loa (eye worm) hypothetical protein 0.0107 0.0642 0.1646
Echinococcus multilocularis glyceraldehyde 3 phosphate dehydrogenase 0.007 0.0376 0.0385
Trichomonas vaginalis conserved hypothetical protein 0.0042 0.018 0.0282
Loa Loa (eye worm) glutathione reductase 0.0102 0.0607 0.1558
Trichomonas vaginalis PIKK family atypical protein kinase 0.0018 0.001 0.0006
Trichomonas vaginalis PIKK family atypical protein kinase 0.0018 0.001 0.0006
Trypanosoma cruzi iron superoxide dismutase A, mitochondrial 0.0068 0.0367 0.2639
Echinococcus multilocularis ecdysone induced protein 78C 0.0059 0.03 0.0308
Plasmodium falciparum dihydrolipoyl dehydrogenase, mitochondrial 0.0035 0.0134 0.1952
Echinococcus granulosus cpg binding protein 0.0063 0.0331 0.0339
Loa Loa (eye worm) hypothetical protein 0.0122 0.0746 0.1913
Brugia malayi Muscleblind-like protein 0.0301 0.2022 0.5186
Schistosoma mansoni hypothetical protein 0.004 0.0169 0.0173
Trypanosoma brucei polo-like protein kinase 0.0094 0.0551 0.3976
Loa Loa (eye worm) histone methyltransferase 0.002 0.0025 0.0065
Mycobacterium leprae conserved hypothetical protein 0.0037 0.0144 0.011
Schistosoma mansoni amine oxidase 0.0021 0.0034 0.0035
Loa Loa (eye worm) hypothetical protein 0.0301 0.2022 0.5186
Trichomonas vaginalis CAMK family protein kinase 0.0094 0.0551 0.0883
Echinococcus multilocularis nuclear receptor subfamily 4 group A 0.0028 0.008 0.0081
Leishmania major 2,4-dihydroxyhept-2-ene-1,7-dioic acid aldolase, putative 0.0024 0.0055 0.0329
Mycobacterium tuberculosis Probable soluble pyridine nucleotide transhydrogenase SthA (STH) (NAD(P)(+) transhydrogenase [B-specific]) (nicotinamide nucleot 0.0035 0.0134 0.0115
Echinococcus granulosus ecdysone induced protein 78C 0.0059 0.03 0.0308
Onchocerca volvulus 0.0037 0.0144 0.0338
Trypanosoma cruzi UDP-galactopyranose mutase 0.0021 0.0034 0.0226
Loa Loa (eye worm) pyruvate kinase-PB 0.0047 0.0215 0.0553
Leishmania major glyceraldehyde 3-phosphate dehydrogenase, glycosomal 0.007 0.0376 0.2669
Echinococcus multilocularis Nuclear hormone receptor family member nhr 41 0.0059 0.03 0.0308
Loa Loa (eye worm) hypothetical protein 0.0067 0.036 0.0924
Brugia malayi Bromodomain containing protein 0.0039 0.0161 0.0413
Loa Loa (eye worm) RecQ helicase 0.0022 0.0038 0.0096
Toxoplasma gondii adrenodoxin-type ferredoxin, putative 0.0029 0.0085 0.1013
Echinococcus granulosus ubiquitin specific protease 41 0.0041 0.0173 0.0177
Trypanosoma cruzi dihydrolipoyl dehydrogenase, putative 0.0035 0.0134 0.0946
Mycobacterium ulcerans 4'-phosphopantetheinyl transferase 0.0023 0.0047 0.0024
Brugia malayi beta-lactamase family protein 0.0037 0.0144 0.037
Loa Loa (eye worm) hypothetical protein 0.0068 0.0367 0.0941
Echinococcus multilocularis COUP TF:Svp nuclear hormone receptor 0.0059 0.03 0.0308
Entamoeba histolytica glyceraldehyde-3-phosphate dehydrogenase, putative 0.007 0.0376 0.0902
Giardia lamblia Pyruvate kinase 0.0067 0.036 0.0863
Schistosoma mansoni cpg binding protein 0.0058 0.0294 0.0301
Loa Loa (eye worm) hypothetical protein 0.01 0.0591 0.1515
Trypanosoma brucei glyceraldehyde-3-phosphate dehydrogenase, putative 0.0046 0.0205 0.1466
Schistosoma mansoni nuclear receptor 0.0028 0.008 0.0081
Trichomonas vaginalis chromobox protein, putative 0.0042 0.0178 0.0279
Leishmania major dihydrolipoamide dehydrogenase, putative 0.0035 0.0134 0.0903
Loa Loa (eye worm) phosphatidylinositol glycan anchor biosynthesis protein 0.0047 0.0216 0.0555
Leishmania major hypothetical protein, conserved 0.0039 0.0158 0.1078
Toxoplasma gondii NADPH-glutathione reductase 0.0035 0.0134 0.1669
Trichomonas vaginalis CMGC family protein kinase 0.0053 0.0255 0.0403
Echinococcus granulosus single minded 2 0.0037 0.0144 0.0148
Trichomonas vaginalis conserved hypothetical protein 0.0039 0.0158 0.0245
Trichomonas vaginalis CAMK family protein kinase 0.0094 0.0551 0.0883
Echinococcus granulosus pyruvate kinase 0.0067 0.036 0.0369
Brugia malayi Calcitonin receptor-like protein seb-1 0.006 0.031 0.0794
Trichomonas vaginalis PIKK family atypical protein kinase 0.0018 0.001 0.0006
Trichomonas vaginalis CMGC family protein kinase 0.0053 0.0255 0.0403
Onchocerca volvulus 0.0479 0.3284 1
Echinococcus multilocularis dna polymerase eta 0.002 0.0023 0.0023
Onchocerca volvulus 0.0073 0.0399 0.1123
Brugia malayi TAR-binding protein 0.0065 0.0343 0.088
Trichomonas vaginalis m-phase inducer phosphatase, putative 0.0116 0.0706 0.1133
Trichomonas vaginalis CMGC family protein kinase 0.0053 0.0255 0.0403
Echinococcus multilocularis protein dispatched 1 0.0048 0.0222 0.0227
Loa Loa (eye worm) nuclear hormone receptor family member nhr-1 0.0059 0.03 0.0771
Trypanosoma cruzi mitogen-activated protein kinase 11, putative 0.0053 0.0255 0.1827
Loa Loa (eye worm) hypothetical protein 0.0028 0.008 0.0204
Mycobacterium leprae conserved hypothetical protein 0.0023 0.0047 0.0013
Onchocerca volvulus Adrenodoxin, mitochondrial homolog 0.0029 0.0085 0.0155
Leishmania major mitogen activated protein kinase 4, putative;with=GeneDB:LmxM19.1440 0.0053 0.0255 0.1789
Echinococcus granulosus FKBP12 rapamycin complex associated protein 0.0018 0.001 0.001
Trichomonas vaginalis conserved hypothetical protein 0.0027 0.0077 0.0115
Mycobacterium ulcerans putative regulatory protein 0.0037 0.0144 0.0122
Brugia malayi nuclear receptor NHR-88 0.0028 0.008 0.0204
Mycobacterium ulcerans hypothetical protein 0.0037 0.0144 0.0122
Trypanosoma brucei dihydrolipoamide dehydrogenase 0.0035 0.0134 0.0946
Echinococcus multilocularis Niemann Pick C1 protein 0.014 0.0874 0.0895
Brugia malayi beta-lactamase family protein 0.0037 0.0144 0.037
Echinococcus granulosus pyruvate kinase 0.0035 0.0128 0.0131
Trichomonas vaginalis Ferredoxin 6 0.0029 0.0085 0.0128
Trypanosoma cruzi Phosphatidylinositol 3-kinase tor1 0.0018 0.001 0.0047
Schistosoma mansoni hypothetical protein 0.0023 0.0044 0.0045
Trichomonas vaginalis m-phase inducer phosphatase, putative 0.0116 0.0706 0.1133
Onchocerca volvulus 0.003 0.0098 0.0196
Echinococcus granulosus muscleblind protein 0.0301 0.2022 0.207
Echinococcus granulosus arachidonate 5 lipoxygenase 0.0136 0.0848 0.0868
Brugia malayi Thioredoxin reductase 0.0102 0.0607 0.1558
Schistosoma mansoni hypothetical protein 0.0041 0.0174 0.0179
Echinococcus multilocularis chromobox protein 1 0.0069 0.0373 0.0382
Giardia lamblia NADH oxidase lateral transfer candidate 0.0035 0.0134 0.0305
Toxoplasma gondii fructose-1,6-bisphosphate aldolase 0.0093 0.0543 0.7187
Trypanosoma cruzi adrenodoxin precursor, putative 0.0029 0.0085 0.0592
Echinococcus granulosus chromobox protein 1 0.0069 0.0373 0.0382
Mycobacterium tuberculosis Probable oxidoreductase 0.0118 0.0717 0.072
Loa Loa (eye worm) hypothetical protein 0.0053 0.0261 0.0671
Brugia malayi Phosphatidylinositol 3- and 4-kinase family protein 0.0018 0.001 0.0025
Loa Loa (eye worm) hypothetical protein 0.0054 0.0269 0.0689
Mycobacterium tuberculosis holo-[acyl-carrier protein] synthase AcpS (holo-ACP synthase) (CoA:APO-[ACP]pantetheinephosphotransferase) (CoA:APO-[acyl-carrie 0.0023 0.0047 0.0025
Echinococcus multilocularis pyruvate kinase 0.0035 0.0128 0.0131
Echinococcus multilocularis fructose 1,6 bisphosphate aldolase 0.0093 0.0543 0.0556
Onchocerca volvulus Serine\/threonine kinase homolog 0.0094 0.0551 0.1591
Echinococcus multilocularis thioredoxin glutathione reductase 0.0103 0.0611 0.0626
Loa Loa (eye worm) latrophilin receptor protein 2 0.0019 0.0018 0.0045
Trichomonas vaginalis CAMK family protein kinase 0.0094 0.0551 0.0883
Mycobacterium tuberculosis Probable esterase/lipase LipP 0.0037 0.0144 0.0126
Leishmania major glyceraldehyde-3-phosphate dehydrogenase-like protein 0.0046 0.0205 0.1426
Trypanosoma brucei protein kinase, putative 0.0053 0.0255 0.1827
Trichomonas vaginalis set domain proteins, putative 0.0479 0.3284 0.5305
Onchocerca volvulus Heterochromatin protein 1 homolog 0.0039 0.0158 0.0379
Loa Loa (eye worm) hypothetical protein 0.0028 0.008 0.0204
Trypanosoma brucei pyruvate kinase 1 0.0067 0.036 0.2589
Brugia malayi Glyceraldehyde 3-phosphate dehydrogenase 0.0024 0.0052 0.0135
Schistosoma mansoni amine oxidase 0.0021 0.0034 0.0035
Brugia malayi orphan nuclear receptor NR2E1 0.0028 0.008 0.0204
Trypanosoma cruzi PAB1-binding protein , putative 0.0051 0.0243 0.1741
Trichomonas vaginalis PIKK family atypical protein kinase 0.0018 0.001 0.0006
Brugia malayi Nuclear hormone receptor family member nhr-1 0.0059 0.03 0.0771
Treponema pallidum glyceraldehyde 3-phosphate dehydrogenase (gap) 0.007 0.0376 0.0817
Trichomonas vaginalis PIKK family atypical protein kinase 0.0018 0.001 0.0006
Leishmania major ferredoxin, 2fe-2s-like protein 0.0029 0.0085 0.0548
Loa Loa (eye worm) phosphatidylinositol 3 0.0018 0.001 0.0025
Schistosoma mansoni glyceraldehyde-3-phosphate dehydrogenase (phosphorylating) 0.007 0.0376 0.0385
Mycobacterium ulcerans pyruvate kinase 0.0067 0.036 0.0338
Brugia malayi beta-lactamase 0.0037 0.0144 0.037
Echinococcus multilocularis neuropeptide receptor A26 0.0459 0.3141 0.3216
Loa Loa (eye worm) TAR-binding protein 0.0065 0.0343 0.088
Echinococcus granulosus pyruvate kinase 0.0035 0.0128 0.0131
Trypanosoma brucei DNA polymerase kappa, putative 0.002 0.0023 0.0141
Giardia lamblia Kinase, CMGC MAPK 0.0053 0.0255 0.0605
Mycobacterium ulcerans fusion of enoyl-CoA hydratase, EchA21 and lipase, LipE 0.0037 0.0144 0.0122
Brugia malayi aminoadipate-semialdehyde dehydrogenase-phosphopantetheinyl transferase 0.0083 0.0468 0.1201
Loa Loa (eye worm) hypothetical protein 0.0059 0.03 0.0771
Trypanosoma cruzi glyceraldehyde 3-phosphate dehydrogenase, C-terminal domain, putative 0.0022 0.0035 0.0231
Toxoplasma gondii pyruvate kinase PyK1 0.0067 0.036 0.472
Echinococcus multilocularis mitogen activated protein kinase 3 0.0053 0.0255 0.0261
Trypanosoma cruzi UDP-galactopyranose mutase 0.0021 0.0034 0.0226
Plasmodium vivax superoxide dismutase [Fe], putative 0.0039 0.0157 0.2142
Echinococcus granulosus lysine specific histone demethylase 1A 0.0021 0.0034 0.0035
Toxoplasma gondii glyceraldehyde-3-phosphate dehydrogenase GAPDH2 0.007 0.0376 0.4932
Brugia malayi Phosphatidylinositol 3- and 4-kinase family protein 0.0025 0.0057 0.0147
Loa Loa (eye worm) hypothetical protein 0.0028 0.008 0.0204
Trichomonas vaginalis chromodomain helicase DNA binding protein, putative 0.0024 0.0056 0.0081
Trichomonas vaginalis chromodomain helicase DNA binding protein, putative 0.0024 0.0056 0.0081
Echinococcus multilocularis histone lysine N methyltransferase SETMAR 0.0061 0.0319 0.0326
Brugia malayi photoreceptor-specific nuclear receptor 0.0059 0.03 0.0771
Trypanosoma cruzi DNA polymerase kappa, putative 0.002 0.0023 0.0141
Plasmodium falciparum dihydrolipoyl dehydrogenase, apicoplast 0.0035 0.0134 0.1952
Leishmania major hypothetical protein, conserved 0.0037 0.0144 0.098
Wolbachia endosymbiont of Brugia malayi ferredoxin 0.0029 0.0085 0.1151
Echinococcus granulosus cytoplasmic intermediate filament protein 0.0026 0.0069 0.007
Plasmodium vivax pyruvate kinase, putative 0.0067 0.036 0.5682
Treponema pallidum fructose-bisphosphate aldolase 0.059 0.4068 1
Echinococcus multilocularis ubiquitin specific protease 41 0.0041 0.0173 0.0177
Mycobacterium leprae PROBABLE NADH DEHYDROGENASE NDH 0.0092 0.0533 0.05
Plasmodium vivax glutathione reductase, putative 0.0102 0.0607 1
Entamoeba histolytica glucosamine-6-phosphate isomerase, putative 0.0047 0.0216 0.0509
Plasmodium falciparum conserved Plasmodium protein, unknown function 0.0021 0.0034 0.0267
Trypanosoma cruzi mitogen activated protein kinase 4, putative 0.0053 0.0255 0.1827
Schistosoma mansoni nuclear receptor 0.0028 0.008 0.0081
Loa Loa (eye worm) nuclear Hormone Receptor family member 0.0059 0.03 0.0771
Trichomonas vaginalis DNA helicase recq1, putative 0.0022 0.0038 0.0051
Trypanosoma brucei ubiquitin carboxyl-terminal hydrolase, putative 0.0041 0.0173 0.1232
Mycobacterium leprae N-Acetyl-1-D-myo-Inosityl-2-Amino-2-Deoxy-alpha-D-Glucopyranoside Deacetylase MshB (GlcNAc-Ins deacetylase) 0.0047 0.0216 0.0182
Mycobacterium tuberculosis Probable conserved lipoprotein 0.0037 0.0144 0.0126
Entamoeba histolytica hypothetical protein 0.0023 0.0047 0.0092
Mycobacterium ulcerans flavin-containing monoamine oxidase AofH 0.0304 0.2042 0.2024
Loa Loa (eye worm) hypothetical protein 0.0047 0.0216 0.0554
Brugia malayi hypothetical protein 0.0028 0.008 0.0204
Plasmodium vivax dihydrolipoyl dehydrogenase, mitochondrial, putative 0.0035 0.0134 0.1731
Trypanosoma cruzi myo-inositol-1(or 4)-monophosphatase 1, putative 0.0038 0.0151 0.1072
Trichomonas vaginalis pyruvate kinase, putative 0.0067 0.036 0.0573
Schistosoma mansoni hypothetical protein 0.0049 0.0233 0.0239
Trichomonas vaginalis chromodomain helicase DNA binding protein, putative 0.0024 0.0056 0.0081
Brugia malayi RNA binding protein 0.0065 0.0343 0.088
Trichomonas vaginalis inositol monophosphatase, putative 0.0038 0.0151 0.0235
Loa Loa (eye worm) heterochromatin protein 1 0.0069 0.0373 0.0957
Brugia malayi nuclear hormone receptor family member nhr-6 0.0028 0.008 0.0204
Echinococcus multilocularis bromodomain adjacent to zinc finger domain 0.0037 0.0144 0.0147
Mycobacterium ulcerans flavodoxin oxidoreductase 0.0029 0.0085 0.0062
Mycobacterium leprae Probable superoxide dismutase SodA 0.0068 0.0367 0.0334
Schistosoma mansoni polycystin 1-related 0.0023 0.0044 0.0045
Trypanosoma cruzi adrenodoxin precursor, putative 0.0029 0.0085 0.0592
Loa Loa (eye worm) hypothetical protein 0.0242 0.1602 0.4111
Trypanosoma brucei NADH-ubiquinone oxidoreductase complex I subunit, putative 0.0029 0.0085 0.0592
Mycobacterium ulcerans hypothetical protein 0.0024 0.0055 0.0032
Loa Loa (eye worm) hypothetical protein 0.0059 0.03 0.0771
Brugia malayi nuclear hormone receptor 0.0059 0.03 0.0771
Brugia malayi ImpB/MucB/SamB family protein 0.002 0.0023 0.0058
Trichomonas vaginalis PIKK family atypical protein kinase 0.0018 0.001 0.0006
Echinococcus granulosus FTZ F1 alpha 0.0059 0.03 0.0308
Onchocerca volvulus Protein ultraspiracle homolog 0.0059 0.03 0.0819
Mycobacterium ulcerans citrate (pro-3S)-lyase subunit beta 0.0024 0.0055 0.0032
Echinococcus granulosus histone lysine N methyltransferase MLL3 0.002 0.0025 0.0026
Trypanosoma cruzi dihydrolipoamide dehydrogenase, putative 0.0035 0.0134 0.0946
Entamoeba histolytica fructose-1,6-bisphosphate aldolase, putative 0.059 0.4068 1
Trypanosoma cruzi target of rapamycin kinase 3 0.0018 0.001 0.0047
Brugia malayi Nuclear hormone receptor E75 0.0028 0.008 0.0204
Trypanosoma cruzi ubiquitin carboxyl-terminal hydrolase, putative 0.0041 0.0173 0.1232
Trypanosoma cruzi fructose-bisphosphate aldolase, glycosomal, putative 0.0093 0.0543 0.3917
Trichomonas vaginalis penicillin-binding protein, putative 0.0037 0.0144 0.0224
Brugia malayi Corticotropin releasing factor receptor 2 precursor, putative 0.006 0.031 0.0794
Leishmania major UDP-galactopyranose mutase 0.0021 0.0034 0.018
Trypanosoma cruzi trypanothione reductase, putative 0.0102 0.0607 0.4384
Schistosoma mansoni hypothetical protein 0.0019 0.0018 0.0018
Plasmodium vivax thioredoxin reductase, putative 0.0102 0.0607 1
Brugia malayi Latrophilin receptor protein 2 0.0019 0.0018 0.0045
Trypanosoma cruzi iron superoxide dismutase, putative 0.0047 0.0213 0.1522
Entamoeba histolytica hypothetical protein 0.0025 0.0057 0.0117
Brugia malayi Bloom's syndrome protein homolog 0.0022 0.0038 0.0096
Trichomonas vaginalis PIKK family atypical protein kinase 0.0018 0.001 0.0006
Echinococcus granulosus Protein patched homolog 1 0.0042 0.018 0.0184
Schistosoma mansoni tar DNA-binding protein 0.0065 0.0343 0.0351
Echinococcus multilocularis nuclear receptor 2DBD gamma 0.0059 0.03 0.0308
Trichomonas vaginalis PIKK family atypical protein kinase 0.0018 0.001 0.0006
Echinococcus multilocularis ubiquitin carboxyl terminal hydrolase 8 0.0041 0.0173 0.0177
Brugia malayi Ligand-binding domain of nuclear hormone receptor family protein 0.0059 0.03 0.0771
Leishmania major ubiquitin hydrolase, putative,cysteine peptidase, Clan CA, family C19, putative 0.0041 0.0173 0.119
Echinococcus granulosus beta LACTamase domain containing family member 0.0037 0.0144 0.0148
Plasmodium falciparum superoxide dismutase [Fe] 0.0039 0.0157 0.2352
Mycobacterium tuberculosis Possible penicillin-binding protein 0.0236 0.1556 0.159
Schistosoma mansoni histone-lysine n-methyltransferase setb1 0.0061 0.0319 0.0326
Toxoplasma gondii fructose-1,6-bisphosphate aldolase 0.0093 0.0543 0.7187
Trypanosoma cruzi glyceraldehyde 3-phosphate dehydrogenase, cytosolic, putative 0.007 0.0376 0.2703
Loa Loa (eye worm) hypothetical protein 0.0031 0.0103 0.0265
Wolbachia endosymbiont of Brugia malayi dihydrolipoamide dehydrogenase E3 component 0.0035 0.0134 0.2632
Onchocerca volvulus 0.0116 0.0706 0.2067
Plasmodium vivax pyruvate kinase 2, putative 0.0035 0.0128 0.1624
Schistosoma mansoni hydrolase 0.0039 0.0158 0.0161
Trypanosoma brucei inositol-1(or 4)-monophosphatase 1, putative 0.0038 0.0151 0.1072
Loa Loa (eye worm) nuclear hormone receptor family member nhr-14 0.0059 0.03 0.0771
Schistosoma mansoni ataxia telangiectasia mutated (atm)-related 0.0018 0.001 0.001
Mycobacterium leprae Probable fructose bisphosphate aldolase Fba 0.0288 0.1927 0.1899
Schistosoma mansoni N-acetylglucosaminyl-phosphatidylinositol de-n-acetylase 0.0047 0.0216 0.0221
Trichomonas vaginalis CAMK family protein kinase 0.0094 0.0551 0.0883
Echinococcus multilocularis thyroid hormone receptor alpha 0.0184 0.1188 0.1216
Echinococcus multilocularis bloom syndrome protein 0.0022 0.0038 0.0038
Trypanosoma brucei hypothetical protein, conserved 0.0211 0.1381 1
Brugia malayi hypothetical protein 0.0028 0.008 0.0204
Schistosoma mansoni nuclear hormone receptor superfamily protein-related 0.0028 0.008 0.0081
Schistosoma mansoni tar DNA-binding protein 0.0065 0.0343 0.0351
Plasmodium vivax ataxin-2 like protein, putative 0.0051 0.0243 0.3645
Echinococcus granulosus survival motor neuron protein 1 0.0242 0.1602 0.1641
Toxoplasma gondii superoxide dismutase SOD3 0.0068 0.0367 0.4813
Chlamydia trachomatis superoxide dismutase 0.0068 0.0367 0.9742
Loa Loa (eye worm) hypothetical protein 0.0047 0.0215 0.0553
Echinococcus granulosus N acetylglucosaminyl phosphatidylinositol 0.0047 0.0216 0.0221
Echinococcus multilocularis lamin 0.0054 0.0269 0.0275
Trichomonas vaginalis DNA polymerase eta, putative 0.002 0.0023 0.0027
Onchocerca volvulus Nuclear receptor subfamily 6 group A member 1 homolog 0.0028 0.008 0.0139
Schistosoma mansoni hypothetical protein 0.0342 0.2309 0.2365
Plasmodium falciparum protoporphyrinogen oxidase 0.0021 0.0034 0.0267
Schistosoma mansoni terminal deoxycytidyl transferase 0.002 0.0023 0.0023
Trypanosoma cruzi glyceraldehyde-3-phosphate dehydrogenase, putative 0.0046 0.0205 0.1466
Schistosoma mansoni mixed-lineage leukemia protein mll 0.0125 0.077 0.0789
Trypanosoma brucei DNA polymerase kappa, putative 0.002 0.0023 0.0141
Schistosoma mansoni pyruvate kinase 0.0035 0.0128 0.0131
Echinococcus granulosus ubiquitin carboxyl terminal hydrolase 8 0.0041 0.0173 0.0177
Loa Loa (eye worm) hypothetical protein 0.0028 0.008 0.0204
Trypanosoma brucei trypanothione reductase 0.0102 0.0607 0.4384
Trichomonas vaginalis myo inositol monophosphatase, putative 0.0038 0.0151 0.0235
Echinococcus granulosus nuclear receptor 2DBD gamma 0.0059 0.03 0.0308
Schistosoma mansoni lipoxygenase 0.0136 0.0848 0.0868
Giardia lamblia Glucosamine-6-phosphate isomerase, putative 0.0047 0.0216 0.0509
Echinococcus granulosus Niemann Pick C1 protein 0.0098 0.0576 0.059
Mycobacterium tuberculosis NADPH-dependent mycothiol reductase Mtr 0.0102 0.0607 0.0606
Trypanosoma cruzi dihydrolipoamide dehydrogenase, putative 0.0035 0.0134 0.0946
Mycobacterium ulcerans oxygenase 0.0029 0.0085 0.0062
Onchocerca volvulus 0.0116 0.0706 0.2067
Trypanosoma cruzi glyceraldehyde 3-phosphate dehydrogenase, putative 0.007 0.0376 0.2703
Leishmania major 2-oxoglutarate dehydrogenase, e3 component, lipoamidedehydrogenase-like protein 0.0035 0.0134 0.0903
Trypanosoma cruzi N-Acetyl-D-glucosaminylphosphatidylinositol de-N-acetylase, putative 0.0047 0.0216 0.1545
Trichomonas vaginalis xanthine dehydrogenase, putative 0.0888 0.6185 1
Brugia malayi Heterochromatin protein 1 0.0069 0.0373 0.0957
Trichomonas vaginalis PIKK family atypical protein kinase 0.0018 0.001 0.0006
Trichomonas vaginalis CAMK family protein kinase 0.0047 0.0215 0.0339
Mycobacterium tuberculosis Conserved protein 0.0037 0.0144 0.0126
Brugia malayi Nuclear hormone receptor family member nhr-19 0.0059 0.03 0.0771
Echinococcus granulosus 5'partial|histone lysine N methyltransferase SETDB2 0.0058 0.0294 0.0301
Loa Loa (eye worm) CMGC/MAPK/ERK1 protein kinase 0.0053 0.0255 0.0654
Trypanosoma cruzi phosphatidylinositol 3-related kinase, putative 0.0018 0.001 0.0047
Toxoplasma gondii pyruvate kinase PyKII 0.0035 0.0128 0.1587
Plasmodium falciparum thioredoxin reductase 0.0035 0.0134 0.1952
Plasmodium falciparum N-acetylglucosaminylphosphatidylinositol deacetylase, putative 0.0047 0.0216 0.3354
Loa Loa (eye worm) hypothetical protein 0.002 0.0023 0.0058
Onchocerca volvulus Superoxide dismutase [Mn], mitochondrial homolog 0.0047 0.0213 0.055
Trypanosoma cruzi glyceraldehyde 3-phosphate dehydrogenase, putative 0.007 0.0376 0.2703
Loa Loa (eye worm) glyceraldehyde-3-phosphate dehydrogenase 0.0048 0.0223 0.0572
Plasmodium vivax holo-[acyl-carrier-protein] synthase, putative 0.0023 0.0047 0.0221
Mycobacterium tuberculosis Inositol-1-monophosphatase SuhB 0.0034 0.0123 0.0104
Schistosoma mansoni dihydrolipoamide dehydrogenase 0.0035 0.0134 0.0137
Leishmania major glyceraldehyde 3-phosphate dehydrogenase, glycosomal 0.007 0.0376 0.2669
Mycobacterium ulcerans oxidoreductase 0.0021 0.0034 0.0012
Brugia malayi RNA recognition motif domain containing protein 0.0065 0.0343 0.088
Plasmodium vivax ferredoxin, putative 0.0029 0.0085 0.0881
Schistosoma mansoni FTZ-F1 nuclear receptor-like protein 0.0059 0.03 0.0308
Echinococcus granulosus Niemann Pick C1 protein 0.014 0.0874 0.0895
Trypanosoma cruzi iron superoxide dismutase, putative 0.0068 0.0367 0.2639
Entamoeba histolytica hypothetical protein 0.0043 0.0191 0.0446
Entamoeba histolytica hypothetical protein 0.0043 0.0191 0.0446
Mycobacterium ulcerans glyceraldehyde 3-phosphate dehydrogenase Gap 0.007 0.0376 0.0354
Schistosoma mansoni hypothetical protein 0.0566 0.3898 0.3992
Mycobacterium leprae Probable glyceraldehyde 3-phosphate dehydrogenase Gap (GAPDH) 0.0024 0.0053 0.0018
Loa Loa (eye worm) hypothetical protein 0.0072 0.0397 0.1018
Plasmodium falciparum fructose-bisphosphate aldolase 0.0093 0.0543 0.8907
Trypanosoma brucei DNA polymerase kappa, putative 0.002 0.0023 0.0141
Trichomonas vaginalis PIKK family atypical protein kinase 0.0018 0.001 0.0006
Trypanosoma brucei pyruvate kinase 1, putative 0.0067 0.036 0.2589
Echinococcus granulosus tar DNA binding protein 0.0065 0.0343 0.0351
Trichomonas vaginalis chromobox protein, putative 0.0042 0.0178 0.0279
Brugia malayi steroid hormone receptor 0.0059 0.03 0.0771
Loa Loa (eye worm) PHD-finger family protein 0.0021 0.0032 0.0083
Plasmodium falciparum epoxide hydrolase 1 0.0039 0.0158 0.2361
Trichomonas vaginalis fructose-bisphosphate aldolase, putative 0.059 0.4068 0.6574
Brugia malayi bHLH-PAS transcription factor 0.0037 0.0144 0.037
Echinococcus granulosus lysine specific histone demethylase 1A 0.0021 0.0034 0.0035
Trypanosoma brucei hypothetical protein, conserved 0.0037 0.0144 0.1023
Echinococcus multilocularis protoporphyrinogen oxidase 0.0021 0.0034 0.0035
Trichomonas vaginalis penicillin-binding protein, putative 0.0037 0.0144 0.0224
Loa Loa (eye worm) glyceraldehyde 3-phosphate dehydrogenase 0.0046 0.0206 0.0527
Schistosoma mansoni inositol monophosphatase 0.0038 0.0151 0.0155
Onchocerca volvulus 0.0054 0.0269 0.072
Schistosoma mansoni bromodomain containing protein 0.0068 0.0366 0.0375
Trypanosoma brucei hypothetical protein, conserved 0.0023 0.0047 0.0318
Schistosoma mansoni glyceraldehyde-3-phosphate dehydrogenase (phosphorylating) 0.007 0.0376 0.0385
Trypanosoma cruzi Phosphatidylinositol 3-kinase tor2 0.0018 0.001 0.0047
Echinococcus granulosus nuclear receptor subfamily 1 group D 0.0031 0.0103 0.0106
Trichomonas vaginalis glyceraldehyde 3-phosphate dehydrogenase, putative 0.007 0.0376 0.0599
Giardia lamblia Glyceraldehyde 3-phosphate dehydrogenase 0.007 0.0376 0.0902
Plasmodium falciparum pyruvate kinase 2 0.0035 0.0128 0.1848
Loa Loa (eye worm) hypothetical protein 0.0037 0.0144 0.037
Plasmodium vivax SET domain protein, putative 0.0061 0.0319 0.4962
Echinococcus multilocularis Mitotic checkpoint protein PRCC, C terminal 0.0125 0.0769 0.0788
Brugia malayi Uncharacterized LmbE-like protein, COG2120 containing protein 0.0047 0.0216 0.0555
Mycobacterium tuberculosis Conserved protein 0.0024 0.0055 0.0033
Leishmania major trypanothione reductase 0.0102 0.0607 0.4358
Toxoplasma gondii superoxide dismutase SOD2 0.0068 0.0367 0.4813
Echinococcus granulosus nuclear receptor subfamily 4 group A 0.0028 0.008 0.0081
Brugia malayi Nuclear hormone receptor family member nhr-49 0.0059 0.03 0.0771
Trichomonas vaginalis PIKK family atypical protein kinase 0.0018 0.001 0.0006
Mycobacterium tuberculosis Probable hydrolase 0.0037 0.0144 0.0126
Echinococcus multilocularis indoleamine 2,3 dioxygenase 2 0.0566 0.3898 0.3992
Trypanosoma brucei dihydrolipoamide dehydrogenase 0.0035 0.0134 0.0946
Entamoeba histolytica myo-inositol monophosphatase, putative 0.0038 0.0151 0.0348
Schistosoma mansoni glyceraldehyde-3-phosphate dehydrogenase (phosphorylating) 0.007 0.0376 0.0385
Mycobacterium ulcerans extragenic suppressor protein SuhB 0.0038 0.0151 0.0129
Entamoeba histolytica glyceraldehyde-3-phosphate dehydrogenase, putative 0.007 0.0376 0.0902
Loa Loa (eye worm) nuclear hormone receptor family member nhr-31 0.0059 0.03 0.0771
Toxoplasma gondii 4'-phosphopantetheinyl transferase superfamily protein 0.0023 0.0047 0.0503
Mycobacterium ulcerans electron transfer protein FdxB 0.0029 0.0085 0.0062
Trichomonas vaginalis aldehyde oxidase, putative 0.0888 0.6185 1
Brugia malayi nuclear hormone receptor 0.0028 0.008 0.0204
Trypanosoma brucei iron superoxide dismutase 0.0068 0.0367 0.2639
Onchocerca volvulus 0.0028 0.008 0.0139
Trichomonas vaginalis pyruvate kinase, putative 0.0067 0.036 0.0573
Mycobacterium tuberculosis Probable flavin-containing monoamine oxidase AofH (amine oxidase) (MAO) 0.0283 0.189 0.1937
Brugia malayi Nuclear hormone receptor-like 1 0.0031 0.0103 0.0265
Mycobacterium tuberculosis Probable oxidoreductase 0.0029 0.0085 0.0065
Trypanosoma brucei DNA polymerase kappa, putative 0.002 0.0023 0.0141
Echinococcus granulosus aldehyde dehydrogenase mitochondrial 0.0122 0.0752 0.077
Entamoeba histolytica hypothetical protein 0.0043 0.0191 0.0446
Trypanosoma brucei DNA polymerase kappa, putative 0.002 0.0023 0.0141
Brugia malayi hypothetical protein 0.0031 0.0103 0.0265
Trypanosoma brucei DNA polymerase kappa, putative 0.002 0.0023 0.0141
Mycobacterium ulcerans lipase LipD 0.0037 0.0144 0.0122
Echinococcus multilocularis retinoic acid receptor rxr beta a retinoic acid receptor rxr alpha a retinoic acid receptor rxr alpha 0.0028 0.008 0.0081
Loa Loa (eye worm) hypothetical protein 0.0028 0.008 0.0204
Echinococcus granulosus Ataxin 2 N terminaldomain containing protein 0.0023 0.0044 0.0045
Schistosoma mansoni rab6-interacting 0.0023 0.0044 0.0045
Trypanosoma cruzi dihydrolipoamide dehydrogenase, putative 0.0035 0.0134 0.0946
Loa Loa (eye worm) hypothetical protein 0.0019 0.0018 0.0045
Schistosoma mansoni histone-lysine n-methyltransferase setb1 0.0079 0.0443 0.0454
Trichomonas vaginalis mitotic inducer phosphatase CDC25, putative 0.0116 0.0706 0.1133
Loa Loa (eye worm) hypothetical protein 0.0028 0.008 0.0204
Schistosoma mansoni rab6-interacting 0.0023 0.0044 0.0045
Loa Loa (eye worm) hypothetical protein 0.0021 0.0034 0.0088
Trichomonas vaginalis PIKK family atypical protein kinase 0.0018 0.001 0.0006
Wolbachia endosymbiont of Brugia malayi fructose-1,6-bisphosphatase 0.0038 0.0151 0.3161
Mycobacterium ulcerans superoxide dismutase [Fe] SodA 0.0068 0.0367 0.0345
Schistosoma mansoni kinase 0.0048 0.0224 0.0229
Plasmodium vivax dihydrolipoyl dehydrogenase, apicoplast, putative 0.0035 0.0134 0.1731
Mycobacterium ulcerans carbon monoxyde dehydrogenase small chain CoxS 0.0169 0.1086 0.1065
Echinococcus multilocularis nuclear receptor 2DBD gamma 0.0059 0.03 0.0308
Schistosoma mansoni tar DNA-binding protein 0.0065 0.0343 0.0351
Trypanosoma brucei electron transfer protein, putative 0.0029 0.0085 0.0592
Trypanosoma cruzi phosphatidylinositol kinase related protein, putative 0.0025 0.0057 0.0392
Onchocerca volvulus 0.0023 0.0044 0.0028
Loa Loa (eye worm) hypothetical protein 0.0042 0.018 0.0462
Echinococcus multilocularis nuclear receptor 2DBD gamma 0.0028 0.008 0.0081
Schistosoma mansoni inositol monophosphatase 0.0038 0.0151 0.0155
Loa Loa (eye worm) hypothetical protein 0.0041 0.0174 0.0448
Loa Loa (eye worm) nuclear receptor NHR-67 0.0028 0.008 0.0204
Mycobacterium leprae DIHYDROLIPOAMIDE DEHYDROGENASE LPD (LIPOAMIDE REDUCTASE (NADH)) (LIPOYL DEHYDROGENASE) (DIHYDROLIPOYL DEHYDROGENASE) (DIAPHORASE 0.0118 0.0717 0.0685
Mycobacterium tuberculosis Probable carbon monoxyde dehydrogenase (small chain) 0.0169 0.1086 0.1102
Trichomonas vaginalis fructose-bisphosphate aldolase, putative 0.059 0.4068 0.6574
Brugia malayi Pyridine nucleotide-disulphide oxidoreductase, dimerisation domain containing protein 0.0026 0.0067 0.0172
Trichomonas vaginalis Ferredoxin 1 0.0029 0.0085 0.0128
Leishmania major myo-inositol-1(or 4)-monophosphatase 1, putative 0.0038 0.0151 0.103
Echinococcus granulosus cadherin EGF LAG seven pass G type receptor 0.0019 0.0018 0.0018
Trichomonas vaginalis superoxide dismutase, putative 0.0068 0.0367 0.0584
Loa Loa (eye worm) hypothetical protein 0.0059 0.03 0.0771
Echinococcus granulosus lipoxygenase domain containing protein 0.0023 0.0044 0.0045
Trypanosoma cruzi superoxide dismutase, putative 0.0039 0.0157 0.1117
Schistosoma mansoni nuclear hormone receptor 0.0028 0.008 0.0081
Loa Loa (eye worm) hypothetical protein 0.0037 0.0144 0.037
Echinococcus multilocularis tar DNA binding protein 0.0065 0.0343 0.0351
Echinococcus multilocularis terminal deoxycytidyl transferase rev1 0.002 0.0023 0.0023
Echinococcus granulosus nuclear receptor 2DBD gamma 0.0028 0.008 0.0081
Brugia malayi Intermediate filament tail domain containing protein 0.0054 0.0269 0.0689
Onchocerca volvulus Bile acid receptor homolog 0.0059 0.03 0.0819
Treponema pallidum hypothetical protein 0.0119 0.0726 0.1688
Toxoplasma gondii thioredoxin reductase 0.0102 0.0607 0.8054
Schistosoma mansoni hypothetical protein 0.004 0.0169 0.0173
Trichomonas vaginalis fructose-bisphosphate aldolase, putative 0.059 0.4068 0.6574
Echinococcus multilocularis bromodomain adjacent to zinc finger domain 0.0064 0.034 0.0348
Loa Loa (eye worm) pyruvate kinase 0.0067 0.036 0.0924
Brugia malayi F/Y-rich N-terminus family protein 0.0022 0.0038 0.0096
Brugia malayi nuclear receptor subfamily 1, group D, member 1, putative 0.0028 0.008 0.0204
Echinococcus granulosus retinoic acid receptor rxr beta a 0.0059 0.03 0.0308
Plasmodium vivax superoxide dismutase [Fe], putative 0.0068 0.0367 0.5803
Plasmodium vivax fructose 1,6-bisphosphate aldolase, putative 0.0093 0.0543 0.8877
Brugia malayi Iron-sulfur cluster assembly accessory protein 0.0049 0.0233 0.0598
Mycobacterium leprae PROBABLE CONSERVED LIPOPROTEIN LPQF 0.0063 0.0331 0.0298
Trypanosoma cruzi adrenodoxin precursor, putative 0.0029 0.0085 0.0592
Trichomonas vaginalis PIKK family atypical protein kinase 0.0018 0.001 0.0006
Onchocerca volvulus 0.0116 0.0706 0.2067
Loa Loa (eye worm) inositol-1 0.0038 0.0151 0.0387
Schistosoma mansoni RAR-like nuclear receptor 0.0059 0.03 0.0308
Onchocerca volvulus 0.0116 0.0706 0.2067
Loa Loa (eye worm) hypothetical protein 0.0037 0.0144 0.037
Brugia malayi Cytochrome P450 family protein 0.0054 0.0263 0.0674
Echinococcus multilocularis serine protein kinase ATM 0.0025 0.0057 0.0059
Loa Loa (eye worm) RNA recognition domain-containing protein domain-containing protein 0.0065 0.0343 0.088
Onchocerca volvulus Pyruvate kinase homolog 0.0067 0.036 0.1002
Schistosoma mansoni lamin 0.0054 0.0269 0.0275
Echinococcus multilocularis L aminoadipate semialdehyde 0.0083 0.0468 0.0479
Echinococcus granulosus methyl CpG binding domain protein 2 0.0017 0.0006 0.0007
Trypanosoma cruzi DNA polymerase kappa, putative 0.002 0.0023 0.0141
Schistosoma mansoni acetyl-CoA C-acetyltransferase 0.0026 0.007 0.0071
Plasmodium falciparum lysine-specific histone demethylase 1, putative 0.0021 0.0034 0.0267
Leishmania major hypothetical protein, conserved 0.0211 0.1381 1
Trypanosoma cruzi glyceraldehyde 3-phosphate dehydrogenase, cytosolic, putative 0.0022 0.0035 0.0231
Brugia malayi Nuclear hormone receptor family member nhr-25 0.0059 0.03 0.0771
Echinococcus multilocularis glyceraldehyde 3 phosphate dehydrogenase 0.007 0.0376 0.0385
Trichomonas vaginalis fructose-bisphosphate aldolase, putative 0.059 0.4068 0.6574
Mycobacterium ulcerans flavoprotein disulfide reductase 0.0035 0.0134 0.0111
Loa Loa (eye worm) pigment dispersing factor receptor c 0.006 0.031 0.0794
Schistosoma mansoni histone-lysine n-methyltransferase suv9 0.0073 0.0399 0.0409
Echinococcus multilocularis glyceraldehyde 3 phosphate dehydrogenase 0.0046 0.0206 0.0211
Echinococcus multilocularis fructose 1,6 bisphosphate aldolase 0.0093 0.0543 0.0556
Trichomonas vaginalis PIKK family atypical protein kinase 0.0018 0.001 0.0006
Trypanosoma cruzi superoxide dismutase, putative 0.0039 0.0157 0.1117
Trypanosoma cruzi glyceraldehyde 3-phosphate dehydrogenase, cytosolic, putative 0.007 0.0376 0.2703
Mycobacterium tuberculosis Probable lipase LipE 0.0037 0.0144 0.0126
Trichomonas vaginalis mitotic inducer phosphatase CDC25, putative 0.0116 0.0706 0.1133
Schistosoma mansoni m-phase inducer phosphatase(cdc25) 0.0116 0.0706 0.0723
Plasmodium falciparum LCCL domain-containing protein 0.0023 0.0044 0.0424
Toxoplasma gondii FATC domain-containing protein 0.0025 0.0057 0.0641
Brugia malayi ecdysone receptor 0.0028 0.008 0.0204
Brugia malayi conserved hypotetical protein 0.0028 0.008 0.0204
Toxoplasma gondii ferodoxin FD 0.0029 0.0085 0.1013
Trichomonas vaginalis PIKK family atypical protein kinase 0.0018 0.001 0.0006
Echinococcus multilocularis sterol regulatory element binding protein 0.0042 0.018 0.0184
Schistosoma mansoni DNA polymerase eta 0.002 0.0023 0.0023
Trichomonas vaginalis cdc25c, putative 0.0116 0.0706 0.1133
Schistosoma mansoni rab geranylgeranyl transferase alpha subunit 0.002 0.0023 0.0023
Entamoeba histolytica rodhanase-like domain containing protein 0.0116 0.0706 0.1715
Trichomonas vaginalis conserved hypothetical protein 0.0041 0.0173 0.0271
Echinococcus granulosus m phase inducer phosphatasecdc25 0.0116 0.0706 0.0723
Loa Loa (eye worm) nuclear hormone receptor 0.0028 0.008 0.0204
Brugia malayi Steroid receptor seven-up type 2 0.0059 0.03 0.0771
Schistosoma mansoni hypothetical protein 0.0019 0.0018 0.0018
Schistosoma mansoni nuclear hormone receptor 0.0028 0.008 0.0081
Entamoeba histolytica iron-containing superoxide dismutase 0.0068 0.0367 0.088
Echinococcus granulosus bloom syndrome protein 0.0022 0.0038 0.0038
Toxoplasma gondii histone lysine methyltransferase SET1 0.0114 0.0694 0.9226
Brugia malayi Nuclear hormone receptor-like 1 0.0031 0.0103 0.0265
Loa Loa (eye worm) hypothetical protein 0.0028 0.008 0.0204
Echinococcus granulosus expressed conserved protein 0.0092 0.0534 0.0547
Trypanosoma brucei DNA polymerase kappa, putative 0.002 0.0023 0.0141
Plasmodium falciparum ataxin-2 like protein, putative 0.0051 0.0243 0.3815
Treponema pallidum hypothetical protein 0.0144 0.0907 0.2138
Mycobacterium tuberculosis Probable citrate (pro-3S)-lyase (beta subunit) CitE (citrase) (citratase) (citritase) (citridesmolase) (citrase aldolase) 0.0024 0.0055 0.0033
Leishmania major iron superoxide dismutase 0.0068 0.0367 0.2604
Echinococcus multilocularis phosphatidylinositol 3 and 4 kinase 0.0018 0.001 0.001
Mycobacterium tuberculosis Probable aldehyde dehydrogenase 0.0122 0.0752 0.0756
Treponema pallidum NADH oxidase 0.0035 0.0134 0.0215
Brugia malayi glyceraldehyde 3-phosphate dehydrogenase 0.0022 0.0035 0.009
Trypanosoma cruzi superoxide dismutase, putative 0.0039 0.0157 0.1117
Loa Loa (eye worm) intermediate filament protein 0.0054 0.0269 0.0689
Echinococcus multilocularis GPCR, family 2 0.0019 0.0018 0.0018
Schistosoma mansoni hypothetical protein 0.0342 0.2309 0.2365
Trichomonas vaginalis glyceraldehyde 3-phosphate dehydrogenase, putative 0.0046 0.0206 0.0323
Brugia malayi hypothetical protein 0.0043 0.0191 0.0489
Brugia malayi hypothetical protein 0.0033 0.0115 0.0296
Loa Loa (eye worm) RNA binding protein 0.0065 0.0343 0.088
Trichomonas vaginalis superoxide dismutase, putative 0.0068 0.0367 0.0584
Echinococcus granulosus glyceraldehyde 3 phosphate dehydrogenase 0.007 0.0376 0.0385
Brugia malayi Phosphatidylinositol 3- and 4-kinase family protein 0.0018 0.001 0.0025
Trichomonas vaginalis PIKK family atypical protein kinase 0.0025 0.0057 0.0083
Plasmodium falciparum glutathione reductase 0.0102 0.0607 1
Brugia malayi Adrenodoxin-like protein, mitochondrial precursor, putative 0.0029 0.0085 0.0218
Loa Loa (eye worm) CXXC zinc finger family protein 0.0058 0.0294 0.0753
Brugia malayi ImpB/MucB/SamB family protein 0.002 0.0023 0.0058
Mycobacterium ulcerans hypothetical protein 0.0024 0.0055 0.0032
Chlamydia trachomatis holo [acyl-carrier protein] synthase 0.0023 0.0047 0.0371
Chlamydia trachomatis pyruvate kinase 0.0067 0.036 0.9539
Brugia malayi Nuclear hormone receptor family member nhr-3 0.0059 0.03 0.0771
Echinococcus granulosus dna polymerase eta 0.002 0.0023 0.0023
Mycobacterium ulcerans fructose-bisphosphate aldolase 0.0288 0.1927 0.1909
Trichomonas vaginalis PIKK family atypical protein kinase 0.0018 0.001 0.0006
Plasmodium vivax glyceraldehyde-3-phosphate dehydrogenase, putative 0.007 0.0376 0.5957
Echinococcus multilocularis diuretic hormone 44 receptor GPRdih2 0.0019 0.0018 0.0018
Brugia malayi Ubiquitin carboxyl-terminal hydrolase family protein 0.0041 0.0173 0.0444
Mycobacterium tuberculosis N-acetyl-1-D-myo-inosityl-2-amino-2-deoxy-alpha-D-glucopyranoside deacetylase MshB (GlcNAc-Ins deacetylase) 0.0047 0.0216 0.0201
Onchocerca volvulus 0.0037 0.0144 0.0338
Schistosoma mansoni hepatocyte nuclear factor 4-alpha (hnf-4-alpha) 0.0028 0.008 0.0081
Loa Loa (eye worm) hypothetical protein 0.0083 0.0468 0.1201
Trypanosoma brucei Alpha/beta hydrolase family, putative 0.0032 0.0109 0.0765
Echinococcus multilocularis m phase inducer phosphatase(cdc25) 0.0116 0.0706 0.0723
Trypanosoma cruzi DNA polymerase kappa, putative 0.002 0.0023 0.0141
Echinococcus granulosus ferredoxin 0.0029 0.0085 0.0087
Mycobacterium tuberculosis Probable nitrite reductase [NAD(P)H] large subunit [FAD flavoprotein] NirB 0.0092 0.0533 0.0529
Loa Loa (eye worm) hypothetical protein 0.0021 0.0034 0.0088
Trichomonas vaginalis fructose-bisphosphate aldolase, putative 0.059 0.4068 0.6574
Entamoeba histolytica pyruvate kinase, putative 0.0047 0.0215 0.0507
Echinococcus multilocularis beta LACTamase domain containing family member 0.0037 0.0144 0.0148

Activities

Activity type Activity value Assay description Source Reference
Potency (functional) 7.9433 uM PUBCHEM_BIOASSAY: qHTS for Inhibitors of binding or entry into cells for Lassa Virus. (Class of assay: confirmatory) [Related pubchem assays (depositor defined):AID463114, AID540249] ChEMBL. No reference
Potency (functional) 10.3225 uM PUBCHEM_BIOASSAY: Nrf2 qHTS screen for inhibitors. (Class of assay: confirmatory) [Related pubchem assays (depositor defined):AID493153, AID493163, AID504648] ChEMBL. No reference
Potency (functional) 10.4179 uM PUBCHEM_BIOASSAY: Primary qHTS for delayed death inhibitors of the malarial parasite plastid, 48 hour incubation. (Class of assay: confirmatory) [Related pubchem assays (depositor defined):AID488752, AID488774, AID504848, AID504850] ChEMBL. No reference
Potency (functional) 11.6891 uM PUBCHEM_BIOASSAY: Primary qHTS for delayed death inhibitors of the malarial parasite plastid, 96 hour incubation. (Class of assay: confirmatory) [Related pubchem assays (depositor defined):AID488745, AID488752, AID488774, AID504848, AID504850] ChEMBL. No reference
Potency (functional) 15.8489 uM PubChem BioAssay. qHTS of GLP-1 Receptor Inverse Agonists (Inhibition Mode). (Class of assay: confirmatory) ChEMBL. No reference
Potency (functional) 20.5962 uM PubChem BioAssay. A quantitative high throughput screen for small molecules that induce DNA re-replication in SW480 colon adenocarcinoma cells. (Class of assay: confirmatory) ChEMBL. No reference
Potency (functional) 28.1838 uM PubChem BioAssay. qHTS for Agonist of gsp, the Etiologic Mutation Responsible for Fibrous Dysplasia/McCune-Albright Syndrome: qHTS. (Class of assay: confirmatory) ChEMBL. No reference
Potency (functional) 29.0929 uM PubChem BioAssay. A quantitative high throughput screen for small molecules that induce DNA re-replication in MCF 10a normal breast cells. (Class of assay: confirmatory) ChEMBL. No reference
Potency (functional) 35.4813 uM PUBCHEM_BIOASSAY: qHTS for Inhibitors of TGF-b: Cytotox Counterscreen. (Class of assay: confirmatory) [Related pubchem assays (depositor defined):AID588855, AID588860] ChEMBL. No reference

Phenotypes

Whole-cell/tissue/organism interactions

Species name Source Reference Is orphan
Homo sapiens ChEMBL23
Plasmodium falciparum ChEMBL23

Many chemical entities in TDR Targets come from high-throughput screenings with whole cells or tissue samples, and not all assayed compounds have been tested against a single a single target protein, probably because they get ruled out during screening process. Even if these compounds may have not been of interest in the original screening, they may come as interesting leads for other screening assays. Furthermore, we may be able to propose drug-target associations using chemical similarities and network patterns.

Annotated phenotypes:

We have no manually annotated phenotypes for this drug. What does this mean? / Care to help?
In TDR Targets, information about phenotypes that are caused by drugs, or by genetic manipulation of cells (e.g. gene knockouts or knockdowns) is manually curated from the literature. These descriptions help to describe the potential of the target for drug development. If no information is available for this gene or if the information is incomplete, this may mean that i) the papers containing this information either appeared after the curation effort for this organism was carried out or they were inadvertently missed by curators; or that ii) the curation effort for this organism has not yet started.
 
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External resources for this compound

Bibliographic References

No literature references available for this target.

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