Detailed information for compound 1463867

Basic information

Technical information
  • Name: Unnamed compound
  • MW: 407.482 | Formula: C24H27N2O4+
  • H donors: 0 H acceptors: 0 LogP: 4.01 Rotable bonds: 6
    Rule of 5 violations (Lipinski): 1
  • SMILES: COc1ccc2c(c1OCCCN(C)C)c[n+]1c(c2)c2cc3OCOc3cc2CC1
  • InChi: 1S/C24H27N2O4/c1-25(2)8-4-10-28-24-19-14-26-9-7-17-12-22-23(30-15-29-22)13-18(17)20(26)11-16(19)5-6-21(24)27-3/h5-6,11-14H,4,7-10,15H2,1-3H3/q+1
  • InChiKey: IESYHXGFZJUKBU-UHFFFAOYSA-N  


Substructure search Similarity search

Network

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Synonyms

No synonyms found for this compound

Targets

Known targets for this compound

No curated genes were found associated with this compound

Predicted pathogen targets for this compound

By orthology
No druggable targets predicted by orthology data
By sequence similarity to non orthologous known druggable targets
No druggable targets predicted by sequence similarity
Obtained from network model

Ranking Plot

Putative Targets List

Species Potential target Raw Global Species
Echinococcus multilocularis DNA (apurinic or apyrimidinic site) lyase 0.0021 0.0036 0.0034
Loa Loa (eye worm) papain family cysteine protease containing protein 0.0047 0.0143 0.0164
Schistosoma mansoni AMP dependent ligase 0.0028 0.0063 0.0066
Echinococcus multilocularis Smad4 0.0016 0.0015 0.0013
Echinococcus granulosus Smad4 0.0016 0.0015 0.0015
Plasmodium vivax acetyl-CoA synthetase, putative 0.01 0.0361 1
Loa Loa (eye worm) beta-LACTamase domain containing family member 0.0038 0.0103 0.0119
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0047 0.0143 0.0649
Mycobacterium ulcerans acyl-CoA synthetase 0.0028 0.0063 0.0054
Mycobacterium ulcerans beta-lactamase 0.0038 0.0103 0.01
Schistosoma mansoni long-chain-fatty-acid--CoA ligase 0.0028 0.0063 0.0066
Entamoeba histolytica acyl-CoA synthetase, putative 0.012 0.0441 0.5609
Echinococcus granulosus arachidonate 5 lipoxygenase 0.0237 0.0924 0.1097
Leishmania major cathepsin L-like protease 0.0047 0.0143 0.0152
Trypanosoma cruzi long-chain-fatty-acid-CoA ligase, putative 0.01 0.0361 0.0421
Toxoplasma gondii histone lysine methyltransferase SET/SUV39 0.0061 0.0201 0.4204
Brugia malayi cathepsin L-like precursor 0.0033 0.0084 0.0088
Mycobacterium ulcerans phenolpthiocerol synthesis type-I polyketide synthase PpsA 0.002 0.0031 0.0017
Mycobacterium ulcerans acyl-CoA synthetase 0.01 0.0361 0.0397
Echinococcus multilocularis beta LACTamase domain containing family member 0.0038 0.0103 0.0101
Mycobacterium ulcerans thioesterase TesA 0.0021 0.0034 0.002
Schistosoma mansoni smad1 5 8 and 0.0016 0.0015 0.0009
Echinococcus granulosus retinoic acid receptor rxr beta a 0.002 0.0032 0.0036
Loa Loa (eye worm) hypothetical protein 0.0028 0.0063 0.0072
Entamoeba histolytica long-chain-fatty-acid--CoA ligase, putative 0.0028 0.0063 0.0381
Echinococcus multilocularis Niemann Pick C1 protein 0.0197 0.0758 0.0756
Mycobacterium tuberculosis Possible conserved lipoprotein LpqK 0.0038 0.0103 0.0117
Mycobacterium leprae Probable lipase LipE 0.0038 0.0103 0.0105
Brugia malayi cathepsin B-like cysteine proteinase 0.0141 0.0528 0.0598
Mycobacterium tuberculosis Probable polyketide synthase Pks1 0.0018 0.0022 0.0018
Chlamydia trachomatis ATP-dependent Clp protease proteolytic subunit 0.0082 0.0284 1
Schistosoma mansoni tar DNA-binding protein 0.0127 0.0471 0.0552
Entamoeba histolytica cysteine proteinase, putative 0.0047 0.0143 0.1482
Mycobacterium tuberculosis Phenyloxazoline synthase MbtB (phenyloxazoline synthetase) 0.0123 0.0457 0.0543
Schistosoma mansoni hypothetical protein 0.0081 0.0283 0.0329
Entamoeba histolytica cysteine protease, putative 0.0047 0.0143 0.1482
Entamoeba histolytica cysteine protease, putative 0.0026 0.0057 0.029
Echinococcus granulosus Protein patched homolog 1 0.0084 0.0296 0.035
Schistosoma mansoni smad1 5 8 and 0.0016 0.0015 0.0009
Loa Loa (eye worm) hypothetical protein 0.0117 0.043 0.0494
Schistosoma mansoni ap endonuclease 0.0021 0.0036 0.0034
Loa Loa (eye worm) AMP-binding enzyme family protein 0.0028 0.0063 0.0072
Echinococcus multilocularis histone lysine methyltransferase setb histone lysine methyltransferase eggless 0.0061 0.0201 0.0199
Plasmodium falciparum cysteine proteinase falcipain 3 0.0047 0.0143 0.3649
Trypanosoma cruzi cysteine peptidase C (CPC), putative 0.0052 0.0162 0.0184
Trypanosoma brucei Emopamil binding protein, putative 0.0276 0.1086 0.3592
Mycobacterium ulcerans long-chain-fatty-acid--CoA ligase 0.01 0.0361 0.0397
Brugia malayi ecdysteroid receptor 0.002 0.0032 0.0029
Schistosoma mansoni TGF-beta signal transducer Smad2 0.0016 0.0015 0.0009
Trichomonas vaginalis penicillin-binding protein, putative 0.0038 0.0103 0.0446
Entamoeba histolytica hypothetical protein 0.0071 0.0243 0.2866
Trichomonas vaginalis long-chain-fatty-acid CoA ligase, putative 0.0028 0.0063 0.0238
Brugia malayi Cathepsin L-like precursor 0.0033 0.0084 0.0088
Trypanosoma cruzi trypanothione reductase, putative 0.0017 0.0017 0.0011
Entamoeba histolytica Niemann-Pick C1 protein, putative 0.0197 0.0758 1
Trypanosoma brucei fatty acyl CoA synthetase 4 0.0028 0.0063 0.0155
Brugia malayi MH2 domain containing protein 0.0237 0.0923 0.1052
Trypanosoma cruzi fatty acyl CoA synthetase 2, putative 0.0028 0.0063 0.0066
Entamoeba histolytica cysteine proteinase 2 0.0026 0.0057 0.029
Leishmania major aldehyde dehydrogenase, mitochondrial precursor 0.0124 0.0458 0.0533
Mycobacterium tuberculosis Probable fatty-acid-CoA ligase FadD8 (fatty-acid-CoA synthetase) (fatty-acid-CoA synthase) 0.01 0.0361 0.0428
Loa Loa (eye worm) MH1 domain-containing protein 0.0016 0.0015 0.0017
Entamoeba histolytica long-chain-fatty-acid--CoA ligase, putative 0.0028 0.0063 0.0381
Echinococcus granulosus expressed protein 0.0017 0.0018 0.0019
Brugia malayi latrophilin 2 splice variant baaae 0.0137 0.0513 0.0581
Brugia malayi calcium-independent alpha-latrotoxin receptor 2, putative 0.0063 0.021 0.0233
Brugia malayi GTP-binding regulatory protein Gs alpha-S chain, putative 0.0091 0.0325 0.0365
Loa Loa (eye worm) intermediate filament protein 0.0027 0.0059 0.0068
Brugia malayi MH2 domain containing protein 0.0016 0.0015 0.0009
Trichomonas vaginalis AMP dependent CoA ligase, putative 0.0028 0.0063 0.0238
Trypanosoma cruzi long-chain-fatty-acid-CoA ligase, putative 0.01 0.0361 0.0421
Mycobacterium tuberculosis Probable bacterioferritin BfrA 0.0017 0.0018 0.0014
Mycobacterium tuberculosis Peptide synthetase MbtF (peptide synthase) 0.0103 0.0372 0.0441
Mycobacterium ulcerans long-chain-fatty-acid-CoA ligase FadD15 0.0028 0.0063 0.0054
Brugia malayi beta-lactamase 0.0038 0.0103 0.011
Loa Loa (eye worm) hypothetical protein 0.002 0.0032 0.0037
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0047 0.0143 0.0422
Mycobacterium tuberculosis Probable fatty-acid-CoA ligase FadD5 (fatty-acid-CoA synthetase) (fatty-acid-CoA synthase) 0.0017 0.0018 0.0013
Plasmodium vivax glutathione reductase, putative 0.0048 0.0146 0.3907
Echinococcus multilocularis protein dispatched 1 0.0096 0.0345 0.0343
Trypanosoma cruzi pantothenate kinase subunit, putative 0.0028 0.0063 0.0066
Brugia malayi Cathepsin L-like precursor 0.0033 0.0084 0.0088
Echinococcus multilocularis expressed conserved protein 0.0185 0.0709 0.0707
Loa Loa (eye worm) hypothetical protein 0.0045 0.0132 0.0152
Schistosoma mansoni tar DNA-binding protein 0.0127 0.0471 0.0552
Echinococcus multilocularis ecdysone induced protein 78C 0.002 0.0032 0.003
Leishmania major cathepsin L-like protease 0.0047 0.0143 0.0152
Schistosoma mansoni hypothetical protein 0.0137 0.0513 0.0602
Trypanosoma brucei fatty acyl CoA syntetase 1 0.0028 0.0063 0.0155
Mycobacterium ulcerans long-chain-fatty-acid-CoA ligase, FadD11 0.0028 0.0063 0.0054
Brugia malayi RNA binding protein 0.0127 0.0471 0.0533
Loa Loa (eye worm) fatty acid synthase 0.0024 0.0049 0.0057
Mycobacterium leprae PHENOLPTHIOCEROL SYNTHESIS TYPE-I POLYKETIDE SYNTHASE PPSB 0.002 0.0031 0.0018
Loa Loa (eye worm) hypothetical protein 0.0028 0.0063 0.0072
Leishmania major cathepsin L-like protease 0.0047 0.0143 0.0152
Brugia malayi Nuclear hormone receptor family member nhr-25 0.002 0.0032 0.0029
Mycobacterium leprae ATP-dependent Clp protease proteolytic subunit 1 0.0028 0.0064 0.0058
Schistosoma mansoni coup transcription factor 0.002 0.0032 0.003
Trypanosoma cruzi acetyl-CoA synthetase, putative 0.01 0.0361 0.0421
Mycobacterium leprae Probable fatty-acid-CoA synthetase FadD29 (fatty-acid-CoA ligase) (fatty-acid-CoA synthase) 0.0028 0.0063 0.0057
Loa Loa (eye worm) nuclear hormone receptor family member nhr-49 0.002 0.0032 0.0037
Mycobacterium leprae PROBABLE THIOESTERASE TESA 0.0021 0.0034 0.0021
Treponema pallidum exodeoxyribonuclease (exoA) 0.0021 0.0036 0.0696
Brugia malayi beta-lactamase family protein 0.0038 0.0103 0.011
Brugia malayi oxidoreductase, zinc-binding dehydrogenase family protein 0.0047 0.0142 0.0155
Plasmodium falciparum acyl-CoA synthetase 0.0028 0.0063 0.134
Schistosoma mansoni histone-lysine n-methyltransferase suv9 0.0061 0.0201 0.0231
Mycobacterium tuberculosis P-hydroxybenzoyl-AMP ligase FadD22 0.0103 0.0372 0.0441
Mycobacterium leprae PROBABLE FATTY-ACID-CoA LIGASE FADD2 (FATTY-ACID-CoA SYNTHETASE) (FATTY-ACID-CoA SYNTHASE) 0.0117 0.043 0.05
Entamoeba histolytica cysteine protease, putative 0.0026 0.0057 0.029
Toxoplasma gondii Acetyl-coenzyme A synthetase 2, putative 0.01 0.0361 0.7817
Loa Loa (eye worm) hypothetical protein 0.0038 0.0103 0.0119
Brugia malayi Papain family cysteine protease containing protein 0.0047 0.0143 0.0155
Brugia malayi Papain family cysteine protease containing protein 0.0026 0.0057 0.0057
Schistosoma mansoni hypothetical protein 0.0063 0.021 0.0241
Mycobacterium ulcerans Type I modular polyketide synthase 0.0025 0.0051 0.004
Trypanosoma cruzi dihydrolipoyl dehydrogenase, putative 0.0017 0.0017 0.0011
Trypanosoma brucei hypothetical protein, conserved 0.0038 0.0103 0.029
Toxoplasma gondii AMP-binding enzyme domain-containing protein 0.004 0.0115 0.2251
Giardia lamblia Endonuclease/Exonuclease/phosphatase 0.0021 0.0036 0.1287
Onchocerca volvulus 0.0143 0.0539 0.2639
Mycobacterium ulcerans acyl-CoA synthetase 0.0117 0.043 0.0477
Loa Loa (eye worm) Papain cysteine protease/cathepsin propeptide inhibitor-containing protein 0.0047 0.0143 0.0164
Echinococcus granulosus cathepsin L cysteine protease 0.0026 0.0057 0.0065
Mycobacterium ulcerans polyketide synthase Pks13 0.0037 0.0101 0.0098
Brugia malayi ERG2 and Sigma1 receptor like protein 0.074 0.2995 0.3434
Echinococcus multilocularis guanine nucleotide binding protein G(s) subunit 0.0091 0.0325 0.0323
Echinococcus granulosus Nuclear hormone receptor family member nhr 41 0.002 0.0032 0.0036
Schistosoma mansoni retinoic acid receptor RXR 0.002 0.0032 0.003
Trypanosoma cruzi dihydrolipoamide dehydrogenase, putative 0.0017 0.0017 0.0011
Echinococcus multilocularis FTZ F1 nuclear receptor protein 0.002 0.0032 0.003
Mycobacterium ulcerans phenyloxazoline synthase MbtB 0.0103 0.0372 0.0409
Entamoeba histolytica cysteine protease, putative 0.0026 0.0057 0.029
Mycobacterium tuberculosis Probable membrane bound polyketide synthase Pks6 0.0037 0.0101 0.0114
Plasmodium falciparum acyl-CoA synthetase 0.0045 0.0132 0.3341
Brugia malayi Corticotropin releasing factor receptor 2 precursor, putative 0.0201 0.0774 0.0882
Mycobacterium tuberculosis Probable aldehyde dehydrogenase 0.0124 0.0458 0.0545
Brugia malayi acetyl-Coenzyme A synthetase 2 0.01 0.0361 0.0407
Schistosoma mansoni tyrosyl-DNA phosphodiesterase 0.0066 0.0219 0.0252
Onchocerca volvulus Rap guanine nucleotide exchange factor 1 homolog 0.0183 0.0701 0.3482
Schistosoma mansoni tar DNA-binding protein 0.0127 0.0471 0.0552
Onchocerca volvulus 0.0123 0.0457 0.2211
Onchocerca volvulus 0.0038 0.0103 0.037
Echinococcus granulosus guanine nucleotide binding protein Gs subunit 0.0091 0.0325 0.0384
Loa Loa (eye worm) cytoplasmic intermediate filament protein 0.0014 0.0008 0.0009
Brugia malayi Pre-SET motif family protein 0.0061 0.0201 0.0223
Mycobacterium tuberculosis Possible penicillin-binding protein 0.024 0.0936 0.1122
Leishmania major cathepsin L-like protease 0.0047 0.0143 0.0152
Loa Loa (eye worm) hypothetical protein 0.0033 0.0084 0.0096
Leishmania major fatty acid transporter protein-like protein 0.2027 0.8294 1
Plasmodium vivax acyl-CoA synthetase, putative 0.0045 0.0132 0.3521
Toxoplasma gondii aldehyde dehydrogenase 0.0124 0.0458 1
Mycobacterium tuberculosis Probable fatty acyl-AMP ligase MbtM 0.0028 0.0063 0.0068
Trypanosoma cruzi C-8 sterol isomerase, putative 0.074 0.2995 0.3556
Loa Loa (eye worm) TAR-binding protein 0.0127 0.0471 0.0541
Echinococcus multilocularis guanine nucleotide binding protein G(s) subunit 0.0091 0.0325 0.0323
Loa Loa (eye worm) hypothetical protein 0.0201 0.0774 0.0889
Mycobacterium leprae PHENOLPTHIOCEROL SYNTHESIS TYPE-I POLYKETIDE SYNTHASE PPSC 0.0026 0.0057 0.0049
Loa Loa (eye worm) hypothetical protein 0.0033 0.0084 0.0096
Mycobacterium leprae PHENOLPTHIOCEROL SYNTHESIS TYPE-I POLYKETIDE SYNTHASE PPSD 0.0025 0.0051 0.0042
Toxoplasma gondii ABC1 family protein 0.0038 0.0103 0.1993
Trichomonas vaginalis AMP dependent ligase, putative 0.0028 0.0063 0.0238
Schistosoma mansoni nuclear hormone receptor nor-1/nor-2 0.002 0.0032 0.003
Brugia malayi AMP-binding enzyme family protein 0.0117 0.043 0.0486
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0047 0.0143 0.0422
Echinococcus granulosus disco interacting protein 2 0.0028 0.0063 0.0073
Brugia malayi Disco-interacting protein 2 homolog 0.0028 0.0063 0.0064
Schistosoma mansoni rab6-interacting 0.004 0.0112 0.0124
Schistosoma mansoni thyroid hormone receptor 0.002 0.0032 0.003
Loa Loa (eye worm) hypothetical protein 0.0137 0.0513 0.0589
Mycobacterium leprae Probable multifunctional mycocerosic acid synthase membrane associated enzyme Mas 0.0026 0.0057 0.0049
Echinococcus multilocularis long chain fatty acid coenzyme A ligase 4 0.0028 0.0063 0.0061
Trypanosoma cruzi trypanothione reductase, putative 0.0048 0.0146 0.0165
Plasmodium falciparum conserved Plasmodium protein, unknown function 0.0028 0.0063 0.134
Plasmodium falciparum ATP-dependent Clp protease proteolytic subunit 0.0082 0.0284 0.7765
Echinococcus multilocularis cathepsin b 0.0141 0.0528 0.0526
Echinococcus multilocularis ATP dependent Clp protease proteolytic subunit 0.0082 0.0284 0.0282
Entamoeba histolytica long-chain-fatty-acid--CoA ligase, putative 0.0028 0.0063 0.0381
Mycobacterium leprae Probable polyketide synthase Pks1 0.0026 0.0057 0.0049
Trypanosoma brucei cysteine peptidase C (CPC) 0.0052 0.0162 0.0486
Entamoeba histolytica cysteine protease, putative 0.0026 0.0057 0.029
Schistosoma mansoni cathepsin B-like peptidase (C01 family) 0.0141 0.0528 0.0619
Loa Loa (eye worm) RNA binding protein 0.0127 0.0471 0.0541
Trypanosoma cruzi AMP-binding enzyme, putative 0.0028 0.0063 0.0066
Brugia malayi AMP-binding enzyme family protein 0.0028 0.0063 0.0064
Mycobacterium tuberculosis Putative polyketide synthase Pks16 0.0028 0.0063 0.0068
Trichomonas vaginalis antibiotic synthetase, putative 0.01 0.0361 0.178
Schistosoma mansoni intermediate filament proteins 0.0027 0.0059 0.0062
Loa Loa (eye worm) cathepsin B 0.0052 0.0162 0.0186
Giardia lamblia Long chain fatty acid CoA ligase 5 0.0028 0.0063 0.3188
Mycobacterium tuberculosis Probable nitrite reductase [NAD(P)H] large subunit [FAD flavoprotein] NirB 0.0109 0.0398 0.0472
Onchocerca volvulus 0.0027 0.0059 0.0141
Leishmania major cathepsin L-like protease 0.0047 0.0143 0.0152
Mycobacterium ulcerans acetyl-CoA synthetase 0.01 0.0361 0.0397
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0026 0.0057 0.0133
Mycobacterium ulcerans ATP-dependent Clp protease proteolytic subunit 0.0082 0.0284 0.0309
Schistosoma mansoni Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) 0.0091 0.0325 0.0378
Schistosoma mansoni microtubule-associated protein tau 0.0687 0.2779 0.3299
Trypanosoma cruzi dihydrolipoamide dehydrogenase, putative 0.0017 0.0017 0.0011
Schistosoma mansoni ferritin light chain 0.0017 0.0018 0.0013
Brugia malayi Niemann-Pick C1 protein precursor 0.0197 0.0758 0.0863
Plasmodium falciparum acyl-CoA synthetase 0.0028 0.0063 0.134
Echinococcus multilocularis thioredoxin glutathione reductase 0.0048 0.0146 0.0144
Loa Loa (eye worm) hypothetical protein 0.004 0.0112 0.0128
Schistosoma mansoni polycystin 1-related 0.004 0.0112 0.0124
Brugia malayi hypothetical protein 0.0122 0.0451 0.051
Mycobacterium tuberculosis Bacterioferritin BfrB 0.0017 0.0018 0.0014
Trichomonas vaginalis esterase, putative 0.0038 0.0103 0.0446
Schistosoma mansoni ferritin 0.0017 0.0018 0.0013
Mycobacterium leprae FATTY-ACID-CoA LIGASE FADD26 (FATTY-ACID-COA SYNTHETASE) (FATTY-ACID-CoA SYNTHASE) 0.0028 0.0063 0.0057
Onchocerca volvulus 0.0047 0.0143 0.0575
Echinococcus multilocularis mothers against decapentaplegic 5 0.0016 0.0015 0.0013
Echinococcus multilocularis aldehyde dehydrogenase, mitochondrial 0.0124 0.0458 0.0456
Loa Loa (eye worm) GTP-binding regulatory protein Gs alpha-S chain 0.0091 0.0325 0.0373
Trichomonas vaginalis long-chain-fatty-acid CoA ligase, putative 0.0028 0.0063 0.0238
Plasmodium falciparum acyl-CoA synthetase 0.0028 0.0063 0.134
Loa Loa (eye worm) hypothetical protein 0.0103 0.0374 0.043
Plasmodium falciparum cysteine proteinase falcipain 1 0.0026 0.0057 0.1149
Loa Loa (eye worm) hypothetical protein 0.0183 0.0701 0.0805
Plasmodium vivax dihydrolipoyl dehydrogenase, apicoplast, putative 0.0017 0.0017 0.027
Loa Loa (eye worm) intermediate filament tail domain-containing protein 0.0027 0.0059 0.0068
Schistosoma mansoni cathepsin F (C01 family) 0.0033 0.0084 0.0091
Echinococcus granulosus smad 0.0016 0.0015 0.0015
Leishmania major long-chain-fatty-acid-CoA ligase, putative,acyl-CoA synthetase, putative,fatty acid thiokinase (long chain), putative 0.0028 0.0063 0.0056
Mycobacterium ulcerans acyl-CoA synthetase 0.01 0.0361 0.0397
Loa Loa (eye worm) hypothetical protein 0.0028 0.0063 0.0072
Loa Loa (eye worm) hypothetical protein 0.0033 0.0084 0.0096
Echinococcus multilocularis musashi 0.0027 0.0059 0.0057
Toxoplasma gondii ATP-dependent Clp endopeptidase, proteolytic subunit ClpP domain-containing protein 0.0082 0.0284 0.6081
Loa Loa (eye worm) pre-SET domain-containing protein family protein 0.0428 0.171 0.1964
Entamoeba histolytica cysteine proteinase, putative 0.0033 0.0084 0.067
Entamoeba histolytica hypothetical protein 0.0071 0.0243 0.2866
Trypanosoma brucei acyl-CoA synthetase, putative 0.0028 0.0063 0.0155
Brugia malayi N-terminal motif family protein 0.0183 0.0701 0.0797
Brugia malayi Nuclear hormone receptor family member nhr-19 0.002 0.0032 0.0029
Trichomonas vaginalis AMP dependent ligase/synthetase, putative 0.0028 0.0063 0.0238
Mycobacterium tuberculosis Probable polyketide synthase Pks8 0.002 0.0032 0.0031
Schistosoma mansoni hypothetical protein 0.0081 0.0283 0.0329
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0047 0.0143 0.0649
Trypanosoma cruzi pantothenate kinase subunit, putative 0.0032 0.0081 0.0087
Mycobacterium tuberculosis Probable esterase/lipase LipP 0.0038 0.0103 0.0117
Mycobacterium leprae possible long-chain acyl-CoA synthase 0.2027 0.8294 1
Entamoeba histolytica acyl-CoA synthetase, putative 0.003 0.0073 0.0524
Schistosoma mansoni aldehyde dehydrogenase 0.0124 0.0458 0.0537
Brugia malayi AMP-binding enzyme family protein 0.0117 0.043 0.0486
Giardia lamblia Cathepsin B precursor 0.0052 0.0162 1
Echinococcus multilocularis Nuclear hormone receptor family member nhr 41 0.002 0.0032 0.003
Echinococcus granulosus histone lysine methyltransferase setb 0.0061 0.0201 0.0237
Mycobacterium tuberculosis Probable hydrolase 0.0038 0.0103 0.0117
Trichomonas vaginalis Clan CA, family C1, papain-like cysteine peptidase 0.0047 0.0143 0.0649
Onchocerca volvulus Cathepsin L homolog 0.0047 0.0143 0.0575
Brugia malayi hypothetical protein 0.0071 0.0243 0.027
Mycobacterium ulcerans fusion of enoyl-CoA hydratase, EchA21 and lipase, LipE 0.0038 0.0103 0.01
Wolbachia endosymbiont of Brugia malayi bacterioferritin/cytochrome b1 0.0017 0.0018 0.0044
Brugia malayi beta-lactamase family protein 0.0038 0.0103 0.011
Mycobacterium leprae Putative polyketide synthetase Pks16 0.0028 0.0063 0.0057
Echinococcus granulosus cathepsin l cysteine peptidase 0.0047 0.0143 0.0167
Brugia malayi intermediate filament protein 0.0027 0.0059 0.006
Schistosoma mansoni long-chain-fatty-acid--CoA ligase 0.0028 0.0063 0.0066
Leishmania major hypothetical protein, conserved 0.0028 0.0063 0.0056
Echinococcus granulosus Niemann Pick C1 protein 0.0197 0.0758 0.0899
Leishmania major acetyl-CoA synthetase, putative 0.01 0.0361 0.0416
Mycobacterium ulcerans fatty-acid-CoA ligase FadD11 0.0028 0.0063 0.0054
Mycobacterium ulcerans acyl-CoA synthetase 0.0117 0.043 0.0477
Schistosoma mansoni patched 1 0.0084 0.0296 0.0343
Mycobacterium ulcerans thioesterase 0.0021 0.0034 0.002
Brugia malayi Papain family cysteine protease containing protein 0.0026 0.0057 0.0057
Echinococcus granulosus expressed conserved protein 0.0185 0.0709 0.0841
Brugia malayi Ligand-binding domain of nuclear hormone receptor family protein 0.002 0.0032 0.0029
Plasmodium vivax dihydrolipoyl dehydrogenase, mitochondrial, putative 0.0017 0.0017 0.027
Mycobacterium tuberculosis Probable ATP-dependent CLP protease proteolytic subunit 2 ClpP2 (endopeptidase CLP 2) 0.0053 0.0169 0.0196
Leishmania major fatty acyl CoA synthetase 2, putative 0.0028 0.0063 0.0056
Plasmodium falciparum AP endonuclease (DNA-[apurinic or apyrimidinic site] lyase), putative 0.0021 0.0036 0.0541
Brugia malayi Cathepsin L-like precursor 0.0047 0.0143 0.0155
Brugia malayi hypothetical protein 0.004 0.0112 0.012
Schistosoma mansoni tar DNA-binding protein 0.0127 0.0471 0.0552
Loa Loa (eye worm) hypothetical protein 0.0045 0.0132 0.0152
Echinococcus granulosus cathepsin b 0.0141 0.0528 0.0625
Loa Loa (eye worm) hypothetical protein 0.0027 0.0059 0.0068
Brugia malayi nuclear receptor NHR-88 0.002 0.0032 0.0029
Onchocerca volvulus 0.0276 0.1086 0.5489
Mycobacterium ulcerans phenolpthiocerol synthesis type-I polyketide synthase PpsD 0.0025 0.0051 0.004
Plasmodium falciparum acyl-CoA synthetase 0.0028 0.0063 0.134
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0047 0.0143 0.0422
Trypanosoma cruzi 3-Beta-hydroxysteroid-delta(8), delta(7)-isomerase, putative 0.0276 0.1086 0.1284
Echinococcus granulosus FTZ F1 nuclear receptor protein 0.002 0.0032 0.0036
Giardia lamblia Long chain fatty acid CoA ligase 4 0.0028 0.0063 0.3188
Schistosoma mansoni peptidase Clp (S14 family) 0.0082 0.0284 0.033
Echinococcus granulosus COUP TF:Svp nuclear hormone receptor 0.002 0.0032 0.0036
Loa Loa (eye worm) hypothetical protein 0.002 0.0032 0.0037
Trypanosoma cruzi cysteine peptidase, putative 0.0047 0.0143 0.0161
Mycobacterium leprae PROBABLE BACTERIOFERRITIN BFRA 0.0017 0.0018 0.0002
Loa Loa (eye worm) hypothetical protein 0.01 0.0361 0.0415
Trichomonas vaginalis penicillin-binding protein, putative 0.0038 0.0103 0.0446
Leishmania major 4-coumarate:coa ligase-like protein 0.0117 0.043 0.05
Trypanosoma cruzi 3-Beta-hydroxysteroid-delta(8), delta(7)-isomerase, putative 0.0276 0.1086 0.1284
Toxoplasma gondii type I fatty acid synthase, putative 0.0018 0.0021 0.0145
Schistosoma mansoni long-chain-fatty-acid--CoA ligase 0.0028 0.0063 0.0066
Schistosoma mansoni long-chain-fatty-acid--CoA ligase 0.0028 0.0063 0.0066
Loa Loa (eye worm) nuclear hormone receptor family member nhr-1 0.002 0.0032 0.0037
Trypanosoma cruzi cysteine peptidase, putative 0.0047 0.0143 0.0161
Entamoeba histolytica cysteine protease, putative 0.0026 0.0057 0.029
Mycobacterium ulcerans acyl-CoA synthetase 0.0117 0.043 0.0477
Brugia malayi Nuclear hormone receptor family member nhr-1 0.002 0.0032 0.0029
Brugia malayi photoreceptor-specific nuclear receptor 0.002 0.0032 0.0029
Mycobacterium tuberculosis Bifunctional enzyme MbtA: salicyl-AMP ligase (SAL-AMP ligase) + salicyl-S-ArCP synthetase 0.01 0.0361 0.0428
Loa Loa (eye worm) papain family cysteine protease containing protein 0.0014 0.0007 0.0008
Brugia malayi exodeoxyribonuclease III family protein 0.0021 0.0036 0.0032
Schistosoma mansoni ferritin 0.0017 0.0018 0.0013
Mycobacterium ulcerans exodeoxyribonuclease III protein XthA 0.0021 0.0036 0.0022
Entamoeba histolytica long-chain-fatty-acid--CoA ligase, putative 0.01 0.0361 0.4512
Schistosoma mansoni tar DNA-binding protein 0.0127 0.0471 0.0552
Entamoeba histolytica long-chain-fatty-acid--CoA ligase, putative 0.0028 0.0063 0.0381
Schistosoma mansoni survival motor neuron protein 0.0048 0.0147 0.0166
Mycobacterium tuberculosis Conserved protein 0.0038 0.0103 0.0117
Giardia lamblia Long chain fatty acid CoA ligase 5 0.0028 0.0063 0.3188
Loa Loa (eye worm) steroid hormone receptor 0.002 0.0032 0.0037
Brugia malayi Iron-sulfur cluster assembly accessory protein 0.0048 0.0147 0.016
Brugia malayi Doublecortin family protein 0.004 0.0112 0.012
Schistosoma mansoni lipoxygenase 0.0166 0.063 0.0742
Mycobacterium ulcerans acyl-CoA synthetase 0.01 0.0361 0.0397
Loa Loa (eye worm) oxidoreductase 0.01 0.0361 0.0415
Leishmania major pantothenate kinase subunit, putative 0.0032 0.0081 0.0077
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0026 0.0057 0.0133
Mycobacterium ulcerans acyl-CoA synthetase 0.0103 0.0372 0.0409
Loa Loa (eye worm) hypothetical protein 0.0045 0.0132 0.0152
Schistosoma mansoni SmCL2-like peptidase (C01 family) 0.0026 0.0057 0.0059
Trichomonas vaginalis D-aminoacylase, putative 0.0038 0.0103 0.0446
Plasmodium vivax thioredoxin reductase, putative 0.0048 0.0146 0.3907
Brugia malayi hypothetical protein 0.0028 0.0063 0.0064
Loa Loa (eye worm) MH2 domain-containing protein 0.0237 0.0923 0.106
Echinococcus granulosus diuretic hormone 44 receptor GPRdih2 0.0063 0.021 0.0247
Mycobacterium tuberculosis Probable fatty-acid-CoA ligase FadD34 (fatty-acid-CoA synthetase) (fatty-acid-CoA synthase) 0.0028 0.0063 0.0068
Mycobacterium tuberculosis Probable fatty-acid-CoA ligase FadD3 (fatty-acid-CoA synthetase) (fatty-acid-CoA synthase) 0.0017 0.0018 0.0013
Entamoeba histolytica cysteine protease, putative 0.0026 0.0057 0.029
Loa Loa (eye worm) hypothetical protein 0.0069 0.0235 0.0269
Echinococcus granulosus tar DNA binding protein 0.0127 0.0471 0.0558
Echinococcus granulosus hepatocyte nuclear factor 4 alpha 0.002 0.0032 0.0036
Entamoeba histolytica cysteine proteinase 1, putative 0.0026 0.0057 0.029
Schistosoma mansoni rab6-interacting 0.004 0.0112 0.0124
Echinococcus granulosus ferritin 0.0017 0.0018 0.0019
Toxoplasma gondii AMP-binding enzyme domain-containing protein 0.0028 0.0063 0.1087
Schistosoma mansoni loxhd1 0.004 0.0112 0.0124
Schistosoma mansoni Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) 0.0091 0.0325 0.0378
Loa Loa (eye worm) hypothetical protein 0.0378 0.1505 0.1729
Trypanosoma brucei C-8 sterol isomerase, putative 0.074 0.2995 1
Brugia malayi Nuclear hormone receptor family member nhr-41 0.002 0.0032 0.0029
Trypanosoma cruzi cysteine protease, putative 0.0026 0.0057 0.0059
Loa Loa (eye worm) hypothetical protein 0.0117 0.043 0.0494
Echinococcus granulosus sterol regulatory element binding protein 0.0084 0.0296 0.035
Onchocerca volvulus 0.0117 0.043 0.2073
Mycobacterium ulcerans bifunctional enzyme MbtA: salicyl-AMP ligase (SAL-AMP ligase) + salicyl-S-ACP synthetase 0.01 0.0361 0.0397
Echinococcus granulosus GPCR family 2 0.0063 0.021 0.0247
Toxoplasma gondii AMP-binding enzyme domain-containing protein 0.0028 0.0063 0.1087
Schistosoma mansoni lipoxygenase 0.0237 0.0924 0.1091
Brugia malayi glutathione reductase 0.0048 0.0146 0.0159
Plasmodium falciparum LCCL domain-containing protein 0.004 0.0112 0.275
Onchocerca volvulus 0.0487 0.1953 1
Mycobacterium ulcerans long-chain fatty-acid CoA ligase 0.0117 0.043 0.0477
Entamoeba histolytica tyrosyl-DNA phosphodiesterase, putative 0.0066 0.0219 0.2545
Brugia malayi Cathepsin L-like precursor 0.0047 0.0143 0.0155
Mycobacterium tuberculosis Fatty-acid-AMP ligase FadD32 (fatty-acid-AMP synthetase) (fatty-acid-AMP synthase). Also shown to have acyl-ACP ligase activity. 0.0028 0.0063 0.0068
Schistosoma mansoni FFA transport protein 0.2055 0.8409 1
Mycobacterium tuberculosis Probable fatty-acid-CoA ligase FadD11 (fatty-acid-CoA synthetase) (fatty-acid-CoA synthase) 0.0028 0.0063 0.0068
Schistosoma mansoni photoreceptor-specific nuclear receptor related 0.002 0.0032 0.003
Entamoeba histolytica hypothetical protein 0.0028 0.0063 0.0381
Plasmodium falciparum glutathione reductase 0.0048 0.0146 0.3738
Trichomonas vaginalis AMP dependent ligase/synthetase, putative 0.0028 0.0063 0.0238
Loa Loa (eye worm) hypothetical protein 0.002 0.0032 0.0037
Trichomonas vaginalis Clan CA, family C1, cathepsin B-like cysteine peptidase 0.0052 0.0162 0.0748
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0047 0.0143 0.0422
Trypanosoma cruzi cysteine peptidase, putative 0.0047 0.0143 0.0161
Echinococcus multilocularis cathepsin l cysteine peptidase 0.0047 0.0143 0.0141
Echinococcus multilocularis Polycystic kidney disease protein 0.004 0.0112 0.011
Loa Loa (eye worm) nuclear hormone receptor family member nhr-14 0.002 0.0032 0.0037
Entamoeba histolytica cysteine proteinase, putative 0.0047 0.0143 0.1482
Loa Loa (eye worm) tyrosyl-DNA phosphodiesterase 0.0066 0.0219 0.0252
Mycobacterium leprae Probable fatty-acid-CoA synthetase FadD22 (fatty-acid-CoA ligase) (fatty-acid-CoA synthase) 0.0103 0.0372 0.043
Entamoeba histolytica long-chain-fatty-acid--CoA ligase, putative 0.0028 0.0063 0.0381
Brugia malayi hypothetical protein 0.0028 0.0063 0.0064
Echinococcus multilocularis Niemann Pick C1 protein 0.0281 0.1105 0.1103
Trichomonas vaginalis Clan CA, family C1, papain-like cysteine peptidase 0.0047 0.0143 0.0649
Plasmodium vivax vivapain-2 0.0047 0.0143 0.382
Loa Loa (eye worm) hypothetical protein 0.0197 0.0758 0.087
Mycobacterium ulcerans long-chain-fatty-acid--CoA ligase 0.0028 0.0063 0.0054
Echinococcus multilocularis tar DNA binding protein 0.0127 0.0471 0.0469
Schistosoma mansoni nuclear receptor 2DBD-gamma 0.002 0.0032 0.003
Mycobacterium ulcerans bacterioferritin BfrA 0.0017 0.0018 0.0002
Schistosoma mansoni Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) 0.0091 0.0325 0.0378
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0047 0.0143 0.0422
Trypanosoma cruzi fatty acyl CoA syntetase 1, putative 0.0028 0.0063 0.0066
Echinococcus granulosus lamin dm0 0.0027 0.0059 0.0068
Brugia malayi Beta-ketoacyl synthase, N-terminal domain containing protein 0.0025 0.0051 0.005
Mycobacterium ulcerans dihydrolipoamide dehydrogenase 0.0017 0.0017 0.0001
Mycobacterium tuberculosis Probable peptide synthetase Nrp (peptide synthase) 0.0103 0.0372 0.0441
Schistosoma mansoni FAA1 Long-chain-fatty-acid--CoA ligase 1 0.0028 0.0063 0.0066
Mycobacterium ulcerans bacterioferritin BfrB 0.0017 0.0018 0.0002
Echinococcus granulosus long chain fatty acid coenzyme A ligase 1 0.0028 0.0063 0.0073
Echinococcus multilocularis long chain fatty acid coenzyme A ligase 5 0.0028 0.0063 0.0061
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0047 0.0143 0.0649
Echinococcus granulosus TGF beta signal transducer SmadC 0.0016 0.0015 0.0015
Mycobacterium tuberculosis Probable polyketide synthase Pks7 0.0026 0.0057 0.0061
Schistosoma mansoni smad1 5 8 and 0.0016 0.0015 0.0009
Echinococcus granulosus long chain fatty acid coenzyme A ligase 1 0.0028 0.0063 0.0073
Leishmania major long-chain-fatty-acid-CoA ligase, putative 0.01 0.0361 0.0416
Loa Loa (eye worm) hypothetical protein 0.0038 0.0103 0.0119
Echinococcus multilocularis cathepsin L 0.0026 0.0057 0.0055
Loa Loa (eye worm) hypothetical protein 0.0061 0.0201 0.0231
Entamoeba histolytica cysteine protease, putative 0.0026 0.0057 0.029
Leishmania major 4-coumarate:coa ligase-like protein 0.0117 0.043 0.05
Onchocerca volvulus Cathepsin F homolog 0.0047 0.0143 0.0575
Leishmania major C-8 sterol isomerase-like protein 0.074 0.2995 0.3597
Toxoplasma gondii NADPH-glutathione reductase 0.0017 0.0017 0.0046
Loa Loa (eye worm) hypothetical protein 0.0014 0.0007 0.0008
Loa Loa (eye worm) RNA recognition domain-containing protein domain-containing protein 0.0127 0.0471 0.0541
Entamoeba histolytica cysteine proteinase, putative 0.0026 0.0057 0.029
Mycobacterium tuberculosis Probable fatty-acid-CoA ligase FadD2 (fatty-acid-CoA synthetase) (fatty-acid-CoA synthase) 0.0117 0.043 0.0511
Toxoplasma gondii exonuclease III APE 0.0021 0.0036 0.0467
Mycobacterium tuberculosis Probable multifunctional mycocerosic acid synthase membrane-associated Mas 0.0026 0.0057 0.0061
Brugia malayi Cathepsin L-like precursor 0.0047 0.0143 0.0155
Plasmodium falciparum ATP-dependent Clp protease proteolytic subunit 0.0028 0.0064 0.1376
Onchocerca volvulus 0.0038 0.0103 0.037
Onchocerca volvulus Fatty acid synthase homolog 0.0045 0.0133 0.0523
Loa Loa (eye worm) hypothetical protein 0.0045 0.0132 0.0152
Loa Loa (eye worm) hypothetical protein 0.0014 0.0007 0.0008
Trypanosoma brucei long-chain-fatty-acid-CoA ligase, putative 0.01 0.0361 0.1157
Entamoeba histolytica cysteine protease, putative 0.0026 0.0057 0.029
Mycobacterium tuberculosis Probable acyl-CoA ligase FadD31 (acyl-CoA synthetase) (acyl-CoA synthase) 0.0028 0.0063 0.0068
Toxoplasma gondii cathepsin B 0.0052 0.0162 0.3311
Echinococcus multilocularis nuclear receptor 2DBD gamma 0.002 0.0032 0.003
Mycobacterium tuberculosis Probable medium chain fatty-acid-CoA ligase FadD14 (fatty-acid-CoA synthetase) (fatty-acid-CoA synthase) 0.01 0.0361 0.0428
Mycobacterium leprae conserved hypothetical protein 0.0038 0.0103 0.0105
Echinococcus multilocularis cadherin EGF LAG seven pass G type receptor 0.0063 0.021 0.0208
Loa Loa (eye worm) hypothetical protein 0.0122 0.0451 0.0518
Entamoeba histolytica cysteine proteinase, putative 0.0026 0.0057 0.029
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0047 0.0143 0.0649
Giardia lamblia Cathepsin B precursor 0.0052 0.0162 1
Mycobacterium tuberculosis Fatty-acid-CoA synthetase FadD17 (fatty-acid-CoA synthase) (fatty-acid-CoA ligase) 0.01 0.0361 0.0428
Plasmodium vivax vivapain-2 0.0047 0.0143 0.382
Plasmodium falciparum cysteine proteinase falcipain 2a 0.0047 0.0143 0.3649
Entamoeba histolytica long-chain-fatty-acid--CoA ligase, putative 0.0028 0.0063 0.0381
Schistosoma mansoni cathepsin B-like peptidase (C01 family) 0.0141 0.0528 0.0619
Leishmania major 4-coumarate:coa ligase-like protein 0.0117 0.043 0.05
Giardia lamblia Long chain fatty acid CoA ligase 5 0.0028 0.0063 0.3188
Brugia malayi hypothetical protein 0.0236 0.0921 0.105
Brugia malayi Thioredoxin reductase 0.0048 0.0146 0.0159
Plasmodium vivax AP endonuclease (DNA-[apurinic or apyrimidinic site] lyase), putative 0.0021 0.0036 0.0796
Onchocerca volvulus 0.0038 0.0103 0.037
Mycobacterium tuberculosis Possible fatty-acid-CoA ligase FadD10 (fatty-acid-CoA synthetase) (fatty-acid-CoA synthase) 0.01 0.0361 0.0428
Brugia malayi Nuclear hormone receptor family member nhr-19 0.002 0.0032 0.0029
Onchocerca volvulus 0.0033 0.0084 0.0269
Loa Loa (eye worm) nuclear hormone receptor family member nhr-40 0.002 0.0032 0.0037
Echinococcus multilocularis dihydrolipoamide dehydrogenase 0.0017 0.0017 0.0015
Trypanosoma cruzi fatty acyl CoA syntetase 1, putative 0.0028 0.0063 0.0066
Echinococcus granulosus cathepsin L cysteine proteinase 0.0047 0.0143 0.0167
Loa Loa (eye worm) hypothetical protein 0.002 0.0032 0.0037
Schistosoma mansoni smad 0.0016 0.0015 0.0009
Leishmania major trypanothione reductase 0.0048 0.0146 0.0156
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0033 0.0084 0.0346
Mycobacterium ulcerans polyketide synthase 0.0026 0.0057 0.0047
Echinococcus granulosus cathepsin l1 0.0033 0.0084 0.0097
Entamoeba histolytica hypothetical protein 0.0071 0.0243 0.2866
Trypanosoma cruzi cruzipain precursor, putative 0.0047 0.0143 0.0161
Brugia malayi AMP-binding enzyme family protein 0.0123 0.0457 0.0517
Echinococcus multilocularis cathepsin L cysteine protease 0.0047 0.0143 0.0141
Plasmodium vivax unspecified product 0.0026 0.0057 0.1388
Trypanosoma cruzi fatty acid transporter protein-like, putative 0.2055 0.8409 1
Mycobacterium leprae Probable fatty-acid-CoA synthetase FadD28 (fatty-acid-CoA ligase) (fatty-acid-CoA synthase) 0.0028 0.0063 0.0057
Leishmania major long-chain-fatty-acid-CoA ligase, putative 0.0028 0.0063 0.0056
Trichomonas vaginalis Clan CA, family C1, papain-like cysteine peptidase 0.0047 0.0143 0.0649
Echinococcus multilocularis expressed protein 0.0017 0.0018 0.0016
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0033 0.0084 0.0346
Schistosoma mansoni SmCL2-like peptidase (C01 family) 0.0026 0.0057 0.0059
Echinococcus multilocularis hepatocyte nuclear factor 4 alpha 0.002 0.0032 0.003
Echinococcus granulosus acetyl coenzyme A synthetase cytoplasmic 0.01 0.0361 0.0428
Mycobacterium ulcerans aldehyde dehydrogenase 0.0124 0.0458 0.0509
Brugia malayi CHE-14 protein 0.0084 0.0296 0.0332
Mycobacterium leprae PROBABLE ATP-DEPENDENT CLP PROTEASE PROTEOLYTIC SUBUNIT 2 CLPP2 (ENDOPEPTIDASE CLP 2) 0.0082 0.0284 0.0324
Toxoplasma gondii AMP-binding enzyme domain-containing protein 0.0028 0.0063 0.1087
Loa Loa (eye worm) Smad1 0.0016 0.0015 0.0017
Onchocerca volvulus 0.0028 0.0063 0.0161
Echinococcus granulosus cadherin EGF LAG seven pass G type receptor 0.0063 0.021 0.0247
Brugia malayi AMP-binding enzyme family protein 0.0028 0.0063 0.0064
Loa Loa (eye worm) cysteine protease 0.0047 0.0143 0.0164
Echinococcus granulosus tyrosyl DNA phosphodiesterase 1 0.0066 0.0219 0.0259
Loa Loa (eye worm) hypothetical protein 0.0014 0.0006 0.0007
Mycobacterium ulcerans hypothetical protein 0.0117 0.043 0.0477
Schistosoma mansoni long-chain-fatty-acid--CoA ligase 0.0028 0.0063 0.0066
Mycobacterium leprae PROBABLE FATTY-ACID-CoA LIGASE FADD7 (FATTY-ACID-CoA SYNTHETASE) (FATTY-ACID-CoA SYNTHASE) 0.0117 0.043 0.05
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0047 0.0143 0.0422
Loa Loa (eye worm) abnormal chemotaxis protein 14 0.0084 0.0296 0.034
Entamoeba histolytica long-chain-fatty-acid--CoA ligase, putative 0.0028 0.0063 0.0381
Trypanosoma cruzi Emopamil binding protein, putative 0.0276 0.1086 0.1284
Loa Loa (eye worm) hypothetical protein 0.074 0.2995 0.3439
Mycobacterium ulcerans esterase/lipase LipP 0.0038 0.0103 0.01
Trypanosoma brucei fatty acyl CoA synthetase 2 0.0028 0.0063 0.0155
Schistosoma mansoni ferritin 0.0017 0.0018 0.0013
Schistosoma mansoni RAR-like nuclear receptor 0.002 0.0032 0.003
Mycobacterium leprae Polyketide synthase Pks13 0.0037 0.0101 0.0103
Schistosoma mansoni hypothetical protein 0.004 0.0112 0.0124
Onchocerca volvulus Huntingtin homolog 0.0122 0.0451 0.2179
Schistosoma mansoni apoferritin-2 0.0017 0.0018 0.0013
Echinococcus granulosus transcription factor Dp 1 0.0038 0.0105 0.0123
Plasmodium falciparum acyl-CoA synthetase 0.0028 0.0063 0.134
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0047 0.0143 0.0422
Mycobacterium leprae PHENOLPTHIOCEROL SYNTHESIS TYPE-I POLYKETIDE SYNTHASE PPSA 0.0025 0.0051 0.0042
Wolbachia endosymbiont of Brugia malayi exonuclease III 0.0021 0.0036 0.0696
Loa Loa (eye worm) hypothetical protein 0.0117 0.043 0.0494
Echinococcus multilocularis diuretic hormone 44 receptor GPRdih2 0.0063 0.021 0.0208
Brugia malayi MH1 domain containing protein 0.0016 0.0015 0.0009
Echinococcus granulosus mothers against decapentaplegic 5 0.0016 0.0015 0.0015
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0047 0.0143 0.0649
Echinococcus multilocularis GPCR, family 2 0.0063 0.021 0.0208
Echinococcus multilocularis protein patched 0.0084 0.0296 0.0294
Trypanosoma cruzi long-chain-fatty-acid-CoA ligase, putative 0.0028 0.0063 0.0066
Mycobacterium ulcerans multifunctional mycocerosic acid synthase membrane-associated Mas 0.0026 0.0057 0.0047
Mycobacterium tuberculosis Probable fatty-acid-AMP ligase FadD21 (fatty-acid-AMP synthetase) (fatty-acid-AMP synthase) 0.0028 0.0063 0.0068
Schistosoma mansoni family S12 unassigned peptidase (S12 family) 0.0038 0.0103 0.0114
Echinococcus granulosus cathepsin b 0.0141 0.0528 0.0625
Mycobacterium tuberculosis Probable ATP-dependent CLP protease proteolytic subunit 1 ClpP1 (endopeptidase CLP) 0.0053 0.0169 0.0196
Trichomonas vaginalis Clan CA, family C1, papain-like cysteine peptidase 0.0047 0.0143 0.0649
Trypanosoma cruzi tyrosyl-DNA Phosphodiesterase (Tdp1), putative 0.0066 0.0219 0.0252
Mycobacterium ulcerans acyl-CoA synthetase 0.01 0.0361 0.0397
Echinococcus multilocularis arachidonate 5 lipoxygenase 0.0237 0.0924 0.0922
Echinococcus multilocularis thyroid hormone receptor alpha 0.002 0.0032 0.003
Trichomonas vaginalis AMP dependent ligase/synthetase, putative 0.0028 0.0063 0.0238
Mycobacterium ulcerans Type I modular polyketide synthase 0.0025 0.0051 0.004
Loa Loa (eye worm) AMP-binding enzyme family protein 0.0123 0.0457 0.0525
Trypanosoma cruzi cysteine peptidase C (CPC), putative 0.0141 0.0528 0.0619
Echinococcus granulosus aldehyde dehydrogenase mitochondrial 0.0124 0.0458 0.0543
Echinococcus granulosus survival motor neuron protein 1 0.0236 0.0921 0.1093
Treponema pallidum long-chain-fatty-acid--CoA ligase 0.0028 0.0063 0.1725
Schistosoma mansoni SmCB2 peptidase (C01 family) 0.0141 0.0528 0.0619
Mycobacterium leprae POSSIBLE PEPTIDE SYNTHETASE NRP (PEPTIDE SYNTHASE) 0.0028 0.0063 0.0057
Schistosoma mansoni lamin 0.0027 0.0059 0.0062
Trichomonas vaginalis long-chain-fatty-acid CoA ligase, putative 0.0028 0.0063 0.0238
Mycobacterium leprae PROBABLE NADH DEHYDROGENASE NDH 0.0109 0.0398 0.0461
Treponema pallidum ATP-dependent Clp protease proteolytic subunit 0.0028 0.0064 0.1772
Echinococcus granulosus long chain fatty acid coenzyme A ligase 5 0.0028 0.0063 0.0073
Echinococcus multilocularis microtubule associated protein 2 0.0687 0.2779 0.2777
Leishmania major apurinic/apyrimidinic endonuclease-redox protein 0.0021 0.0036 0.0023
Entamoeba histolytica long-chain-fatty-acid--CoA ligase, putative 0.0028 0.0063 0.0381
Echinococcus multilocularis long chain fatty acid coenzyme A ligase 5 0.0028 0.0063 0.0061
Schistosoma mansoni family S12 unassigned peptidase (S12 family) 0.0038 0.0103 0.0114
Entamoeba histolytica acyl-coA synthetase, putative 0.0117 0.043 0.5467
Plasmodium vivax ATP-dependent Clp protease proteolytic subunit, putative 0.0028 0.0064 0.1609
Schistosoma mansoni FTZ-F1 nuclear receptor-like protein 0.002 0.0032 0.003
Mycobacterium tuberculosis Probable soluble pyridine nucleotide transhydrogenase SthA (STH) (NAD(P)(+) transhydrogenase [B-specific]) (nicotinamide nucleot 0.0017 0.0017 0.0012
Leishmania major hypothetical protein, conserved 0.0276 0.1086 0.1292
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0047 0.0143 0.0649
Loa Loa (eye worm) beta-lactamase 0.0038 0.0103 0.0119
Schistosoma mansoni ap endonuclease 0.0021 0.0036 0.0034
Brugia malayi dihydrolipoyl dehydrogenase, mitochondrial precursor, putative 0.0017 0.0017 0.0011
Mycobacterium tuberculosis Phenolpthiocerol synthesis type-I polyketide synthase PpsD 0.0025 0.0051 0.0053
Trichomonas vaginalis conserved hypothetical protein 0.0084 0.0296 0.1441
Schistosoma mansoni dihydrolipoamide dehydrogenase 0.0017 0.0017 0.0011
Loa Loa (eye worm) AMP-binding enzyme family protein 0.2127 0.8707 1
Echinococcus granulosus nuclear receptor 2DBD gamma 0.002 0.0032 0.0036
Echinococcus multilocularis sterol regulatory element binding protein 0.0084 0.0296 0.0294
Trypanosoma brucei long-chain-fatty-acid-CoA ligase, putative 0.0028 0.0063 0.0155
Trypanosoma cruzi dihydrolipoamide dehydrogenase, putative 0.0017 0.0017 0.0011
Echinococcus multilocularis long chain fatty acid coenzyme A ligase 1 0.0028 0.0063 0.0061
Echinococcus granulosus 5'partial|histone lysine N methyltransferase SETDB2 0.0059 0.0192 0.0226
Mycobacterium ulcerans long-chain-acyl-CoA synthetase 0.2127 0.8707 1
Loa Loa (eye worm) hypothetical protein 0.0047 0.0143 0.0164
Plasmodium vivax hypothetical protein, conserved 0.0038 0.0103 0.2708
Trypanosoma brucei fatty acyl CoA synthetase, putative 0.0028 0.0063 0.0155
Schistosoma mansoni hypothetical protein 0.0081 0.0283 0.0329
Echinococcus granulosus long chain fatty acid coenzyme A ligase 5 0.0028 0.0063 0.0073
Echinococcus multilocularis COUP TF:Svp nuclear hormone receptor 0.002 0.0032 0.003
Entamoeba histolytica long-chain-fatty-acid--CoA ligase, putative 0.0028 0.0063 0.0381
Mycobacterium tuberculosis Fatty-acid-AMP ligase FadD30 (fatty-acid-AMP synthetase) (fatty-acid-AMP synthase) 0.0045 0.0132 0.0151
Entamoeba histolytica long-chain-fatty-acid--CoA ligase, putative 0.0028 0.0063 0.0381
Mycobacterium ulcerans acyl-CoA synthetase 0.01 0.0361 0.0397
Loa Loa (eye worm) hypothetical protein 0.002 0.0032 0.0037
Leishmania major hypothetical protein, conserved 0.0038 0.0103 0.0104
Trypanosoma cruzi cysteine peptidase, putative 0.0047 0.0143 0.0161
Trichomonas vaginalis AMP dependent ligase/synthetase, putative 0.0028 0.0063 0.0238
Brugia malayi oxidoreductase, short chain dehydrogenase/reductase family protein 0.0103 0.0372 0.0419
Brugia malayi Nuclear hormone receptor family member nhr-49 0.002 0.0032 0.0029
Schistosoma mansoni hypothetical protein 0.0071 0.0243 0.028
Loa Loa (eye worm) hypothetical protein 0.002 0.0032 0.0037
Trichomonas vaginalis Clan CA, family C1, papain-like cysteine peptidase 0.0047 0.0143 0.0649
Trypanosoma brucei tyrosyl-DNA Phosphodiesterase (Tdp1), putative 0.0066 0.0219 0.068
Echinococcus granulosus intermediate filament protein 0.0027 0.0059 0.0068
Mycobacterium tuberculosis Probable membrane NADH dehydrogenase NdhA 0.0109 0.0398 0.0472
Mycobacterium ulcerans non-ribosomal peptide synthetase MbtF 0.0103 0.0372 0.0409
Mycobacterium tuberculosis Fatty-acid-AMP ligase FadD29 (fatty-acid-AMP synthetase) (fatty-acid-AMP synthase) 0.0028 0.0063 0.0068
Mycobacterium tuberculosis Probable conserved lipoprotein 0.0038 0.0103 0.0117
Mycobacterium tuberculosis Probable chain -fatty-acid-CoA ligase FadD13 (fatty-acyl-CoA synthetase) 0.0117 0.043 0.0511
Loa Loa (eye worm) hypothetical protein 0.0038 0.0103 0.0119
Echinococcus multilocularis ferritin 0.0017 0.0018 0.0016
Mycobacterium leprae Probable long-chain-fatty-acid-CoA ligase FadD15 (FATTY-ACID-CoA SYNTHETASE) (FATTY-ACID-CoA SYNTHASE) 0.0028 0.0063 0.0057
Trichomonas vaginalis AMP dependent ligase, putative 0.0028 0.0063 0.0238
Entamoeba histolytica hypothetical protein 0.0071 0.0243 0.2866
Onchocerca volvulus 0.0061 0.0201 0.088
Plasmodium falciparum acyl-CoA synthetase 0.0028 0.0063 0.134
Loa Loa (eye worm) hypothetical protein 0.0082 0.0284 0.0327
Onchocerca volvulus Cathepsin L homolog 0.0047 0.0143 0.0575
Mycobacterium ulcerans flavoprotein disulfide reductase 0.0017 0.0017 0.0001
Brugia malayi steroid hormone receptor 0.002 0.0032 0.0029
Brugia malayi Hypothetical 52.5 kDa protein ZK945.1 in chromosome II, putative 0.0038 0.0103 0.011
Mycobacterium tuberculosis Polyketide synthase Pks12 0.0026 0.0057 0.0061
Loa Loa (eye worm) exodeoxyribonuclease III family protein 0.0021 0.0036 0.0041
Brugia malayi Intermediate filament tail domain containing protein 0.0027 0.0059 0.006
Loa Loa (eye worm) transcription factor SMAD2 0.0237 0.0923 0.106
Schistosoma mansoni hypothetical protein 0.0063 0.021 0.0241
Trypanosoma cruzi cysteine peptidase, clan CA, family C1, cathepsin L-like, putative 0.0033 0.0084 0.0091
Brugia malayi Nuclear hormone receptor family member nhr-25 0.002 0.0032 0.0029
Trichomonas vaginalis ferritin, putative 0.0017 0.0018 0.0006
Toxoplasma gondii AMP-binding enzyme domain-containing protein 0.01 0.0361 0.7817
Echinococcus multilocularis histone lysine N methyltransferase SETMAR 0.0061 0.0201 0.0199
Schistosoma mansoni ferritin 0.0017 0.0018 0.0013
Brugia malayi hypothetical protein 0.004 0.0112 0.012
Treponema pallidum bacterioferrin (TpF1) 0.0017 0.0018 0.0044
Trypanosoma cruzi fatty acyl CoA synthetase 2, putative 0.0028 0.0063 0.0066
Trichomonas vaginalis set domain proteins, putative 0.0487 0.1953 1
Trypanosoma cruzi tyrosyl-DNA Phosphodiesterase (Tdp1), putative 0.0066 0.0219 0.0252
Trypanosoma cruzi acetyl-CoA synthetase, putative 0.01 0.0361 0.0421
Echinococcus granulosus cathepsin L 0.0026 0.0057 0.0065
Echinococcus multilocularis TGF beta signal transducer SmadC 0.0016 0.0015 0.0013
Echinococcus granulosus ecdysone induced protein 78C 0.002 0.0032 0.0036
Schistosoma mansoni histone-lysine n-methyltransferase setb1 0.0061 0.0201 0.0231
Onchocerca volvulus Huntingtin homolog 0.0122 0.0451 0.2179
Echinococcus multilocularis peptidase Clp (S14 family) 0.0053 0.0169 0.0167
Brugia malayi AMP-binding enzyme family protein 0.0035 0.0094 0.01
Echinococcus granulosus lipoxygenase domain containing protein 0.004 0.0112 0.013
Echinococcus granulosus guanine nucleotide binding protein Gs subunit 0.0091 0.0325 0.0384
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0047 0.0143 0.0649
Schistosoma mansoni cathepsin F (C01 family) 0.0047 0.0143 0.0161
Mycobacterium tuberculosis Probable oxidoreductase 0.0121 0.0448 0.0533
Trichomonas vaginalis antibiotic synthetase, putative 0.01 0.0361 0.178
Schistosoma mansoni apoferritin-2 0.0017 0.0018 0.0013
Echinococcus granulosus ATP dependent Clp protease proteolytic subunit 0.0082 0.0284 0.0336
Brugia malayi Nuclear hormone receptor family member nhr-3 0.002 0.0032 0.0029
Schistosoma mansoni steroid hormone receptor ad4bp 0.002 0.0032 0.003
Trichomonas vaginalis AMP dependent ligase/synthetase, putative 0.0028 0.0063 0.0238
Mycobacterium tuberculosis PROBABLE FATTY-ACID-CoA LIGASE FADD18 (FRAGMENT) (FATTY-ACID-CoA SYNTHETASE) (FATTY-ACID-CoA SYNTHASE) 0.0072 0.0247 0.029
Leishmania major cathepsin L-like protease 0.0047 0.0143 0.0152
Schistosoma mansoni niemann-pick C1 (NPC1) 0.02 0.077 0.0908
Trichomonas vaginalis Clan CA, family C1, papain-like cysteine peptidase 0.0047 0.0143 0.0649
Schistosoma mansoni disco-interacting protein 2 (dip2) 0.0028 0.0063 0.0066
Loa Loa (eye worm) doublecortin family protein 0.004 0.0112 0.0128
Echinococcus granulosus long chain fatty acid coenzyme A ligase 4 0.0028 0.0063 0.0073
Schistosoma mansoni thyroid hormone receptor 0.002 0.0032 0.003
Trypanosoma cruzi dihydrolipoamide dehydrogenase, putative 0.0017 0.0017 0.0011
Loa Loa (eye worm) hypothetical protein 0.0141 0.0528 0.0606
Echinococcus multilocularis transcription factor Dp 1 0.0038 0.0105 0.0103
Treponema pallidum ATP-dependent Clp protease proteolytic subunit 0.0082 0.0284 1
Echinococcus multilocularis tyrosyl DNA phosphodiesterase 1 0.0066 0.0219 0.0217
Loa Loa (eye worm) ctsf protein 0.0047 0.0143 0.0164
Trypanosoma cruzi fatty acyl CoA syntetase 1, putative 0.0028 0.0063 0.0066
Mycobacterium tuberculosis Polyketide synthase Pks2 0.0024 0.0048 0.0049
Trypanosoma brucei pantothenate kinase subunit, putative 0.0028 0.0063 0.0155
Trypanosoma cruzi fatty acyl CoA synthetase 2, putative 0.0028 0.0063 0.0066
Loa Loa (eye worm) thioredoxin reductase 0.0048 0.0146 0.0167
Mycobacterium ulcerans fatty-acid-CoA ligase 0.0028 0.0063 0.0054
Toxoplasma gondii cathepsin CPL 0.0047 0.0143 0.2882
Brugia malayi TAR-binding protein 0.0127 0.0471 0.0533
Echinococcus granulosus cathepsin l1 0.0047 0.0143 0.0167
Echinococcus multilocularis long chain fatty acid transport protein 4 0.2055 0.8409 0.8408
Plasmodium vivax SET domain protein, putative 0.0061 0.0201 0.5475
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0047 0.0143 0.0422
Trypanosoma brucei fatty acyl CoA synthetase, putative 0.0028 0.0063 0.0155
Trypanosoma cruzi cysteine proteinase, putative 0.0026 0.0057 0.0059
Leishmania major 3-Beta-hydroxysteroid-delta(8), delta(7)-isomerase, putative 0.0276 0.1086 0.1292
Leishmania major long-chain-fatty-acid-CoA ligase, putative 0.0028 0.0063 0.0056
Mycobacterium ulcerans non-ribosomal peptide synthetase MbtE 0.0103 0.0372 0.0409
Echinococcus granulosus Polycystic kidney disease protein 0.004 0.0112 0.013
Trichomonas vaginalis AMP dependent ligase/synthetase, putative 0.0028 0.0063 0.0238
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0047 0.0143 0.0649
Trypanosoma cruzi fatty acyl CoA synthetase 2, putative 0.0028 0.0063 0.0066
Mycobacterium tuberculosis Phenolpthiocerol synthesis type-I polyketide synthase PpsC 0.0025 0.0051 0.0053
Entamoeba histolytica acyl-CoA synthetase, putative 0.0117 0.043 0.5467
Echinococcus granulosus long chain fatty acid transport protein 4 0.2055 0.8409 1
Wolbachia endosymbiont of Brugia malayi ATP-dependent Clp protease proteolytic subunit 0.0082 0.0284 1
Mycobacterium ulcerans fatty-acid-CoA ligase 0.0028 0.0063 0.0054
Schistosoma mansoni cathepsin F (C01 family) 0.0047 0.0143 0.0161
Trypanosoma cruzi apurinic/apyrimidinic endonuclease, putative 0.0021 0.0036 0.0034
Mycobacterium leprae PROBABLE ATP-DEPENDENT CLP PROTEASE PROTEOLYTIC SUBUNIT 1 CLPP1 (ENDOPEPTIDASE CLP) 0.0053 0.0169 0.0184
Mycobacterium ulcerans fatty-acid-CoA ligase 0.0117 0.043 0.0477
Loa Loa (eye worm) hypothetical protein 0.0028 0.0063 0.0072
Mycobacterium ulcerans phenolpthiocerol synthesis type-I polyketide synthase PpsB 0.002 0.0031 0.0017
Mycobacterium tuberculosis Probable exodeoxyribonuclease III protein XthA (exonuclease III) (EXO III) (AP endonuclease VI) 0.0021 0.0036 0.0035
Plasmodium falciparum acyl-CoA synthetase 0.0028 0.0063 0.134
Echinococcus multilocularis cathepsin b 0.0141 0.0528 0.0526
Onchocerca volvulus 0.0047 0.0143 0.0575
Mycobacterium tuberculosis Probable reductase 0.0109 0.0398 0.0472
Brugia malayi Probable ClpP-like protease 0.0082 0.0284 0.0319
Leishmania major fatty acyl CoA syntetase 1, putative 0.0028 0.0063 0.0056
Trichomonas vaginalis Clan CA, family C1, papain-like cysteine peptidase 0.0047 0.0143 0.0649
Echinococcus multilocularis cysteine protease 0.0047 0.0143 0.0141
Mycobacterium ulcerans O-succinylbenzoic acid--CoA ligase 0.01 0.0361 0.0397
Toxoplasma gondii propionate-CoA ligase 0.01 0.0361 0.7817
Mycobacterium ulcerans ATP-dependent Clp protease proteolytic subunit 0.0082 0.0284 0.0309
Trichomonas vaginalis AMP dependent ligase/synthetase, putative 0.0028 0.0063 0.0238
Echinococcus multilocularis acetyl coenzyme A synthetase, cytoplasmic 0.01 0.0361 0.0359
Brugia malayi Cathepsin L-like precursor 0.0047 0.0143 0.0155
Plasmodium vivax vivapain-3 0.0026 0.0057 0.1388
Mycobacterium ulcerans non-ribosomal peptide synthetase 0.003 0.0073 0.0066
Trypanosoma cruzi fatty acid transporter protein-like, putative 0.2055 0.8409 1
Leishmania major long chain fatty Acyl CoA synthetase, putative 0.0028 0.0063 0.0056
Mycobacterium tuberculosis Probable fatty-acid-CoA ligase FadD7 (fatty-acid-CoA synthetase) (fatty-acid-CoA synthase) 0.0017 0.0018 0.0013
Mycobacterium leprae PROBABLE FATTY-ACID--CoA LIGASE FADD21 (FATTY-ACID-CoA SYNTHETASE) (FATTY-ACID-CoA SYNTHASE) 0.0028 0.0063 0.0057
Echinococcus multilocularis lamin dm0 0.0027 0.0059 0.0057
Brugia malayi Smad1 0.0016 0.0015 0.0009
Leishmania major cysteine peptidase C (CPC),CPC cysteine peptidase, Clan CA, family C1, Cathepsin B-like 0.0052 0.0162 0.0175
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0047 0.0143 0.0649
Mycobacterium leprae POSSIBLE FATTY-ACID-CoA LIGASE FADD10 (FATTY-ACID-CoA SYNTHETASE) (FATTY-ACID-CoA SYNTHASE) 0.01 0.0361 0.0417
Mycobacterium tuberculosis Probable fatty-acid-CoA ligase FadD35 (fatty-acid-CoA synthetase) (fatty-acid-CoA synthase) 0.0017 0.0018 0.0013
Leishmania major long-chain-fatty-acid-CoA ligase, putative 0.0028 0.0063 0.0056
Trypanosoma cruzi dihydrolipoamide dehydrogenase, putative 0.0017 0.0017 0.0011
Mycobacterium ulcerans acyl-CoA synthetase 0.0028 0.0063 0.0054
Schistosoma mansoni acetyl-CoA synthetase 0.01 0.0361 0.0421
Trichomonas vaginalis AMP dependent ligase, putative 0.0028 0.0063 0.0238
Mycobacterium tuberculosis Possible fatty-acid-CoA ligase FadD1 (fatty-acid-CoA synthetase) (fatty-acid-CoA synthase) 0.01 0.0361 0.0428
Mycobacterium ulcerans acyl-CoA synthetase 0.0028 0.0063 0.0054
Echinococcus multilocularis long chain fatty acid coenzyme A ligase 1 0.0028 0.0063 0.0061
Mycobacterium ulcerans Type I modular polyketide synthase 0.0025 0.0051 0.004
Mycobacterium ulcerans acyl-CoA synthetase 0.01 0.0361 0.0397
Echinococcus multilocularis acyl coenzyme A synthetase family 0.0028 0.0063 0.0061
Toxoplasma gondii hypothetical protein 0.0028 0.0064 0.1116
Trypanosoma cruzi fatty acyl CoA synthetase 2, putative 0.0028 0.0063 0.0066
Echinococcus granulosus microtubule associated protein 2 0.0687 0.2779 0.3303
Onchocerca volvulus 0.0048 0.0147 0.0597
Schistosoma mansoni SmCL2-like peptidase (C01 family) 0.0026 0.0057 0.0059
Plasmodium vivax long-chain fatty acid CoA ligase, putative 0.0028 0.0063 0.1574
Chlamydia trachomatis ATP-dependent Clp protease proteolytic subunit 0.0082 0.0284 1
Mycobacterium leprae POSSIBLE O-SUCCINYLBENZOIC ACID--CoA LIGASE MENE (OSB-CoA SYNTHETASE) (O-SUCCINYLBENZOATE-CoA SYNTHASE) 0.01 0.0361 0.0417
Plasmodium vivax ATP-dependent acyl-CoA synthetase, putative 0.0028 0.0063 0.1574
Schistosoma mansoni long-chain-fatty-acid--CoA ligase 0.0028 0.0063 0.0066
Entamoeba histolytica acyl-CoA synthetase, putative 0.0028 0.0063 0.0381
Onchocerca volvulus 0.0047 0.0143 0.0575
Echinococcus granulosus FTZ F1 alpha 0.002 0.0032 0.0036
Brugia malayi Ligand-binding domain of nuclear hormone receptor family protein 0.002 0.0032 0.0029
Mycobacterium tuberculosis Probable fatty-acid-AMP ligase FadD25 (fatty-acid-AMP synthetase) (fatty-acid-AMP synthase) 0.0028 0.0063 0.0068
Trypanosoma cruzi dihydrolipoyl dehydrogenase, putative 0.0017 0.0017 0.0011
Leishmania major tyrosyl-DNA phosphodiesterase 1 0.0066 0.0219 0.0245
Trypanosoma brucei Long-chain-fatty-acid--CoA ligase 5 (EC 6.2.1.3) (Long-chain acyl-CoA synthetase 5) (LACS 5), putative 0.0028 0.0063 0.0155
Echinococcus granulosus cysteine protease 0.0026 0.0057 0.0065
Trypanosoma brucei trypanothione reductase 0.0048 0.0146 0.0432
Trypanosoma cruzi hypothetical protein, conserved 0.0038 0.0103 0.0114
Echinococcus granulosus AMP dependent ligase 0.003 0.0073 0.0085
Schistosoma mansoni hypothetical protein 0.0081 0.0283 0.0329
Mycobacterium ulcerans long-chain-fatty-acid--CoA ligase 0.0028 0.0063 0.0054
Entamoeba histolytica cysteine proteinase, putative 0.0026 0.0057 0.029
Trichomonas vaginalis Clan CA, family C1, cathepsin L or K-like cysteine peptidase 0.0047 0.0143 0.0649
Leishmania major cathepsin L-like protease 0.0047 0.0143 0.0152
Mycobacterium ulcerans acyl-CoA synthetase 0.0028 0.0063 0.0054
Brugia malayi MH1 domain containing protein 0.0016 0.0015 0.0009
Schistosoma mansoni histone-lysine n-methyltransferase setb1 0.0061 0.0201 0.0231
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0047 0.0143 0.0649
Plasmodium falciparum acyl-CoA synthetase 0.0028 0.0063 0.134
Plasmodium falciparum thioredoxin reductase 0.0048 0.0146 0.3738
Mycobacterium ulcerans long-chain-fatty-acid--CoA ligase 0.0028 0.0063 0.0054
Echinococcus multilocularis cysteine protease 0.0047 0.0143 0.0141
Trypanosoma brucei acetyl-CoA synthetase, truncated 0.0028 0.0063 0.0155
Giardia lamblia Hypothetical protein 0.0028 0.0063 0.3188
Echinococcus multilocularis FTZ F1 alpha 0.002 0.0032 0.003
Loa Loa (eye worm) hypothetical protein 0.0038 0.0103 0.0119
Mycobacterium tuberculosis Conserved protein 0.0038 0.0103 0.0117
Schistosoma mansoni cathepsin B-like peptidase (C01 family) 0.0052 0.0162 0.0184
Echinococcus multilocularis lipoxygenase domain containing protein 0.004 0.0112 0.011
Loa Loa (eye worm) hypothetical protein 0.0038 0.0103 0.0119
Loa Loa (eye worm) nuclear Hormone Receptor family member 0.002 0.0032 0.0037
Loa Loa (eye worm) hypothetical protein 0.0045 0.0132 0.0152
Echinococcus granulosus beta LACTamase domain containing family member 0.0038 0.0103 0.012
Entamoeba histolytica cysteine protease, putative 0.0026 0.0057 0.029
Trichomonas vaginalis Clan CA, family C1, cathepsin L or K-like cysteine peptidase 0.0047 0.0143 0.0649
Echinococcus multilocularis RUN 0.004 0.0112 0.011
Plasmodium vivax vivapain-1 0.0026 0.0057 0.1388
Trypanosoma cruzi fatty acyl CoA synthetase 2, putative 0.0028 0.0063 0.0066
Schistosoma mansoni aldehyde dehydrogenase 0.0124 0.0458 0.0537
Loa Loa (eye worm) fibroinase 0.0047 0.0143 0.0164
Loa Loa (eye worm) hypothetical protein 0.0028 0.0063 0.0072
Onchocerca volvulus 0.0103 0.0372 0.1768
Toxoplasma gondii hypothetical protein 0.0028 0.0063 0.1087
Mycobacterium ulcerans long-chain-fatty-acid--CoA ligase 0.0117 0.043 0.0477
Mycobacterium tuberculosis Conserved protein 0.0038 0.0103 0.0117
Loa Loa (eye worm) pigment dispersing factor receptor c 0.0201 0.0774 0.0889
Mycobacterium ulcerans fatty-acid-CoA ligase FadD9 0.003 0.0073 0.0066
Mycobacterium tuberculosis Probable lipase LipE 0.0038 0.0103 0.0117
Mycobacterium tuberculosis NADPH-dependent mycothiol reductase Mtr 0.0048 0.0146 0.0168
Mycobacterium ulcerans aldehyde dehydrogenase 0.0124 0.0458 0.0509
Brugia malayi Latrophilin receptor protein 2 0.0063 0.021 0.0233
Trypanosoma cruzi cysteine peptidase, putative 0.0026 0.0057 0.0059
Mycobacterium ulcerans lipase LipD 0.0038 0.0103 0.01
Loa Loa (eye worm) hypothetical protein 0.0026 0.0057 0.0066
Leishmania major acetyl-CoA synthetase, putative 0.01 0.0361 0.0416
Mycobacterium ulcerans long-chain-fatty-acid-CoA ligase FadD15 0.0028 0.0063 0.0054
Trypanosoma brucei fatty acyl CoA synthetase 3 0.0028 0.0063 0.0155
Brugia malayi AMP-binding enzyme family protein 0.0028 0.0063 0.0064
Brugia malayi AMP-binding enzyme family protein 0.01 0.0361 0.0407
Brugia malayi cytoplasmic intermediate filament protein 0.0014 0.0008 0.0001
Trypanosoma cruzi cysteine peptidase (N-terminal), putative 0.0026 0.0057 0.0059
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0047 0.0143 0.0649
Entamoeba histolytica long-chain-fatty-acid--CoA ligase, putative 0.0028 0.0063 0.0381
Mycobacterium tuberculosis Dihydrolipoamide dehydrogenase LpdC (lipoamide reductase (NADH)) (lipoyl dehydrogenase) (dihydrolipoyl dehydrogenase) (diaphoras 0.0121 0.0448 0.0533
Loa Loa (eye worm) hypothetical protein 0.0038 0.0103 0.0119
Plasmodium vivax long-chain-fatty-acid--CoA ligase, putative 0.0028 0.0063 0.1574
Loa Loa (eye worm) hypothetical protein 0.002 0.0032 0.0037
Mycobacterium tuberculosis Probable lipase LipD 0.0038 0.0103 0.0117
Loa Loa (eye worm) hypothetical protein 0.004 0.0112 0.0128
Echinococcus granulosus peptidase Clp S14 family 0.0053 0.0169 0.0198
Mycobacterium ulcerans acyl-CoA synthetase 0.01 0.0361 0.0397
Schistosoma mansoni histone-lysine n-methyltransferase setb1 0.0061 0.0201 0.0231
Mycobacterium tuberculosis Probable dehydrogenase 0.0109 0.0398 0.0472
Loa Loa (eye worm) hypothetical protein 0.0028 0.0063 0.0072
Toxoplasma gondii ATP-dependent Clp endopeptidase, proteolytic subunit ClpP domain-containing protein 0.0082 0.0284 0.6081
Loa Loa (eye worm) AMP-binding enzyme family protein 0.0028 0.0063 0.0072
Mycobacterium tuberculosis Fatty-acid-AMP ligase FadD28 (fatty-acid-AMP synthetase) (fatty-acid-AMP synthase) 0.0028 0.0063 0.0068
Brugia malayi Steroid receptor seven-up type 2 0.002 0.0032 0.0029
Trypanosoma brucei apurinic/apyrimidinic endonuclease, putative 0.0021 0.0036 0.0063
Toxoplasma gondii AMP-binding enzyme domain-containing protein 0.0028 0.0063 0.1087
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0026 0.0057 0.0205
Onchocerca volvulus 0.0047 0.0143 0.0575
Echinococcus multilocularis disco interacting protein 2 0.0028 0.0063 0.0061
Onchocerca volvulus 0.004 0.0112 0.0414
Trypanosoma cruzi fatty acyl CoA synthetase, putative 0.0028 0.0063 0.0066
Giardia lamblia Cathepsin B precursor 0.0052 0.0162 1
Mycobacterium ulcerans aldehyde dehydrogenase 0.0124 0.0458 0.0509
Echinococcus granulosus Niemann Pick C1 protein 0.0281 0.1105 0.1312
Echinococcus multilocularis survival motor neuron protein 1 0.0236 0.0921 0.0919
Echinococcus granulosus DNA apurinic or apyrimidinic site lyase 0.0021 0.0036 0.004
Giardia lamblia Long chain fatty acid CoA ligase, putative 0.0028 0.0063 0.3188
Mycobacterium tuberculosis Probable thioesterase TesA 0.0021 0.0034 0.0033
Loa Loa (eye worm) hypothetical protein 0.0013 0.0002 0.0002
Brugia malayi Cathepsin L-like precursor 0.0047 0.0143 0.0155
Loa Loa (eye worm) hypothetical protein 0.0122 0.0451 0.0518
Brugia malayi AMP-binding enzyme family protein 0.2127 0.8707 1
Schistosoma mansoni retinoid-x-receptor (RXR) 0.002 0.0032 0.003
Echinococcus multilocularis lipoxygenase domain containing protein 0.004 0.0112 0.011
Trichomonas vaginalis ap endonuclease, putative 0.0021 0.0036 0.0096
Entamoeba histolytica cysteine protease, putative 0.0026 0.0057 0.029
Mycobacterium tuberculosis Probable polyketide synthase Pks5 0.0024 0.0048 0.0049
Brugia malayi nuclear hormone receptor 0.002 0.0032 0.0029
Schistosoma mansoni lamin 0.0027 0.0059 0.0062
Brugia malayi Cathepsin L-like precursor 0.0047 0.0143 0.0155
Brugia malayi Pre-SET motif family protein 0.0428 0.171 0.1957
Echinococcus granulosus thioredoxin glutathione reductase 0.0048 0.0146 0.0171
Trichomonas vaginalis ap endonuclease, putative 0.0021 0.0036 0.0096
Entamoeba histolytica cysteine protease, putative 0.0026 0.0057 0.029
Trichomonas vaginalis Clan CA, family C1, papain-like cysteine peptidase 0.0047 0.0143 0.0649
Mycobacterium ulcerans dihydrolipoamide dehydrogenase, LpdB 0.0017 0.0017 0.0001
Loa Loa (eye worm) hypothetical protein 0.0084 0.0296 0.034
Schistosoma mansoni hypothetical protein 0.0063 0.021 0.0241
Brugia malayi AMP-binding enzyme family protein 0.0117 0.043 0.0486
Echinococcus granulosus Basic leucine zipper bZIP transcription 0.0071 0.0243 0.0286
Mycobacterium tuberculosis Probable fatty-acid-CoA ligase FadD6 (fatty-acid-CoA synthetase) (fatty-acid-CoA synthase) 0.2027 0.8294 1
Brugia malayi RNA recognition motif domain containing protein 0.0127 0.0471 0.0533
Echinococcus granulosus lipoxygenase domain containing protein 0.004 0.0112 0.013
Trypanosoma cruzi dihydrolipoamide dehydrogenase, putative 0.0017 0.0017 0.0011
Mycobacterium leprae DIHYDROLIPOAMIDE DEHYDROGENASE LPD (LIPOAMIDE REDUCTASE (NADH)) (LIPOYL DEHYDROGENASE) (DIHYDROLIPOYL DEHYDROGENASE) (DIAPHORASE 0.0121 0.0448 0.0522
Loa Loa (eye worm) hypothetical protein 0.0236 0.0921 0.1057
Trypanosoma cruzi fatty acyl CoA synthetase, putative 0.0028 0.0063 0.0066
Plasmodium falciparum acyl-CoA synthetase 0.0028 0.0063 0.134
Echinococcus multilocularis lamin 0.0027 0.0059 0.0057
Echinococcus multilocularis nuclear receptor 2DBD gamma 0.002 0.0032 0.003
Schistosoma mansoni Tr4/Tr2 (homologue) 0.002 0.0032 0.003
Echinococcus multilocularis cathepsin l cysteine peptidase 0.0047 0.0143 0.0141
Trichomonas vaginalis Clan CA, family C1, papain-like cysteine peptidase 0.0047 0.0143 0.0649
Echinococcus multilocularis cathepsin L cysteine protease 0.0047 0.0143 0.0141
Mycobacterium tuberculosis Fatty-acid-AMP ligase FadD26 (fatty-acid-AMP synthetase) (fatty-acid-AMP synthase) 0.0028 0.0063 0.0068
Leishmania major hypothetical protein, unknown function 0.0028 0.0063 0.0056
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0047 0.0143 0.0422
Toxoplasma gondii pyruvate dehydrogenase complex subunit PDH-E3II 0.0017 0.0017 0.0046
Schistosoma mansoni cathepsin B-like peptidase (C01 family) 0.0141 0.0528 0.0619
Plasmodium falciparum acyl-CoA synthetase 0.0028 0.0063 0.134
Trypanosoma cruzi apurinic/apyrimidinic endonuclease 0.0021 0.0036 0.0034
Giardia lamblia Long chain fatty acid CoA ligase 5 0.0028 0.0063 0.3188
Plasmodium vivax hypothetical protein, conserved 0.0028 0.0063 0.1574
Leishmania major cysteine peptidase A (CPA) 0.0047 0.0143 0.0152
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0047 0.0143 0.0649
Echinococcus multilocularis AMP dependent ligase 0.003 0.0073 0.0071
Mycobacterium tuberculosis Putative ferredoxin reductase 0.0109 0.0398 0.0472
Trypanosoma brucei acetyl-CoA synthetase, putative 0.01 0.0361 0.1157
Echinococcus granulosus nuclear receptor 2DBD gamma 0.002 0.0032 0.0036
Brugia malayi Cathepsin L-like cysteine proteinase 0.0033 0.0084 0.0088
Onchocerca volvulus 0.0047 0.0143 0.0575
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0047 0.0143 0.0422
Trichomonas vaginalis D-aminoacylase, putative 0.0038 0.0103 0.0446
Trypanosoma cruzi cysteine proteinase, putative 0.0026 0.0057 0.0059
Schistosoma mansoni hypothetical protein 0.0063 0.021 0.0241
Plasmodium falciparum acetyl-CoA synthetase, putative 0.01 0.0361 1
Mycobacterium ulcerans fatty-acid-CoA ligase 0.0045 0.0132 0.0133
Echinococcus multilocularis smad 0.0016 0.0015 0.0013
Toxoplasma gondii thioredoxin reductase 0.0048 0.0146 0.2951
Mycobacterium ulcerans peptide synthetase Nrp (peptide synthase) 0.0103 0.0372 0.0409
Brugia malayi AMP-binding enzyme family protein 0.01 0.0361 0.0407
Loa Loa (eye worm) hypothetical protein 0.0014 0.0007 0.0008
Mycobacterium leprae Probable fatty-acid-CoA ligase FadD9 (fatty-acid-CoA synthetase) (fatty-acid-CoA synthase) 0.003 0.0073 0.0069
Loa Loa (eye worm) nuclear hormone receptor family member nhr-41 0.002 0.0032 0.0037
Loa Loa (eye worm) hypothetical protein 0.01 0.0361 0.0415
Mycobacterium tuberculosis Probable NADH dehydrogenase Ndh 0.0109 0.0398 0.0472
Trichomonas vaginalis AMP dependent CoA ligase, putative 0.0028 0.0063 0.0238
Echinococcus granulosus lamin 0.0027 0.0059 0.0068
Trichomonas vaginalis D-aminoacylase, putative 0.0038 0.0103 0.0446
Mycobacterium ulcerans long-chain-fatty-acid-CoA ligase 0.0117 0.043 0.0477
Plasmodium vivax ATP-dependent Clp protease proteolytic subunit, putative 0.0082 0.0284 0.7825
Plasmodium vivax multidomain scavenger receptor, putative 0.004 0.0112 0.2946
Schistosoma mansoni long-chain-fatty-acid--CoA ligase 0.0028 0.0063 0.0066
Mycobacterium ulcerans hypothetical protein 0.0038 0.0103 0.01
Schistosoma mansoni nuclear hormone receptor 0.002 0.0032 0.003
Loa Loa (eye worm) glutathione reductase 0.0048 0.0146 0.0167
Toxoplasma gondii type I fatty acid synthase, putative 0.0054 0.0172 0.3533
Leishmania major cathepsin L-like protease 0.0047 0.0143 0.0152
Echinococcus granulosus acyl coenzyme A synthetase family 0.0028 0.0063 0.0073
Loa Loa (eye worm) latrophilin receptor protein 2 0.0063 0.021 0.0241
Brugia malayi Calcitonin receptor-like protein seb-1 0.0201 0.0774 0.0882
Entamoeba histolytica cysteine proteinase, putative 0.0026 0.0057 0.029
Schistosoma mansoni transcription factor LCR-F1 0.0071 0.0243 0.028
Echinococcus granulosus dihydrolipoamide dehydrogenase 0.0017 0.0017 0.0018
Trypanosoma cruzi hypothetical protein, conserved 0.0038 0.0103 0.0114
Schistosoma mansoni long-chain-fatty-acid--CoA ligase 0.0028 0.0063 0.0066
Loa Loa (eye worm) hypothetical protein 0.002 0.0032 0.0037
Loa Loa (eye worm) MH2 domain-containing protein 0.0016 0.0015 0.0017
Brugia malayi Nuclear hormone receptor family member nhr-14 0.002 0.0032 0.0029
Mycobacterium ulcerans non-ribosomal peptide synthetase 0.0028 0.0063 0.0054
Brugia malayi Nuclear hormone receptor family member nhr-31 0.002 0.0032 0.0029
Schistosoma mansoni Smad4 0.0016 0.0015 0.0009
Mycobacterium tuberculosis NAD(P)H quinone reductase LpdA 0.0121 0.0448 0.0533
Mycobacterium ulcerans polyketide synthase 0.0025 0.0051 0.004
Schistosoma mansoni long-chain-fatty-acid--CoA ligase 0.0028 0.0063 0.0066
Trichomonas vaginalis AMP dependent CoA ligase, putative 0.0028 0.0063 0.0238
Entamoeba histolytica cysteine protease, putative 0.0026 0.0057 0.029
Brugia malayi cDNA sequence BC018371 0.0028 0.0063 0.0064
Schistosoma mansoni hypothetical protein 0.0028 0.0063 0.0066
Onchocerca volvulus 0.01 0.0361 0.1714
Entamoeba histolytica cysteine protease, putative 0.0026 0.0057 0.029
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0047 0.0143 0.0422
Brugia malayi MH2 domain containing protein 0.0016 0.0015 0.0009
Onchocerca volvulus 0.004 0.0112 0.0414
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0047 0.0143 0.0649
Echinococcus multilocularis Basic leucine zipper (bZIP) transcription 0.0071 0.0243 0.0241
Mycobacterium ulcerans phenolpthiocerol synthesis type-I polyketide synthase PpsC 0.0026 0.0057 0.0047
Brugia malayi Tyrosyl-DNA phosphodiesterase family protein 0.0066 0.0219 0.0244
Entamoeba histolytica long-chain-fatty-acid--CoA ligase, putative 0.0028 0.0063 0.0381
Schistosoma mansoni hypothetical protein 0.0048 0.0147 0.0166
Loa Loa (eye worm) hypothetical protein 0.0063 0.021 0.0241
Schistosoma mansoni ferritin light chain 0.0017 0.0018 0.0013
Onchocerca volvulus 0.0027 0.0059 0.0141
Schistosoma mansoni long-chain-fatty-acid--CoA ligase 0.0028 0.0063 0.0066
Mycobacterium ulcerans acyl-CoA synthetase 0.0028 0.0063 0.0054
Mycobacterium tuberculosis Probable esterase LipL 0.0038 0.0103 0.0117
Mycobacterium tuberculosis Polyketide synthase Pks13 0.0037 0.0101 0.0114
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0026 0.0057 0.0205
Trypanosoma cruzi Emopamil binding protein, putative 0.0276 0.1086 0.1284
Echinococcus granulosus RUN 0.004 0.0112 0.013
Loa Loa (eye worm) hypothetical protein 0.0028 0.0063 0.0072
Onchocerca volvulus 0.0047 0.0143 0.0575
Mycobacterium tuberculosis Phenolpthiocerol synthesis type-I polyketide synthase PpsA 0.0025 0.0051 0.0053
Mycobacterium tuberculosis Peptide synthetase MbtE (peptide synthase) 0.0103 0.0372 0.0441
Mycobacterium ulcerans putative fatty-acid--CoA ligase 0.0028 0.0063 0.0054
Chlamydia trachomatis acylglycerophosphoethanolamine acyltransferase 0.0045 0.0132 0.4303
Loa Loa (eye worm) nuclear hormone receptor family member nhr-31 0.002 0.0032 0.0037
Plasmodium falciparum acyl-CoA synthetase 0.0028 0.0063 0.134
Brugia malayi Nuclear hormone receptor-like 1 0.002 0.0032 0.0029
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0047 0.0143 0.0649
Mycobacterium tuberculosis Probable fatty-acid-CoA ligase FadD9 (fatty-acid-CoA synthetase) (fatty-acid-CoA synthase) 0.003 0.0073 0.008
Brugia malayi Nuclear hormone receptor family member nhr-40 0.002 0.0032 0.0029
Onchocerca volvulus 0.0047 0.0143 0.0575
Plasmodium falciparum cysteine proteinase falcipain 2b 0.0047 0.0143 0.3649
Mycobacterium ulcerans long-chain-fatty-acid--CoA ligase 0.0028 0.0063 0.0054

Activities

No activities found for this compound.

Phenotypes

Whole-cell/tissue/organism interactions

We have no records of whole-cell/tissue assays done with this compound What does this mean?

Many chemical entities in TDR Targets come from high-throughput screenings with whole cells or tissue samples, and not all assayed compounds have been tested against a single a single target protein, probably because they get ruled out during screening process. Even if these compounds may have not been of interest in the original screening, they may come as interesting leads for other screening assays. Furthermore, we may be able to propose drug-target associations using chemical similarities and network patterns.

Annotated phenotypes:

We have no manually annotated phenotypes for this drug. What does this mean? / Care to help?
In TDR Targets, information about phenotypes that are caused by drugs, or by genetic manipulation of cells (e.g. gene knockouts or knockdowns) is manually curated from the literature. These descriptions help to describe the potential of the target for drug development. If no information is available for this gene or if the information is incomplete, this may mean that i) the papers containing this information either appeared after the curation effort for this organism was carried out or they were inadvertently missed by curators; or that ii) the curation effort for this organism has not yet started.
 
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External resources for this compound

Bibliographic References

No literature references available for this target.

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