Detailed information for compound 1464765

Basic information

Technical information
  • Name: Unnamed compound
  • MW: 306.397 | Formula: C18H26O4
  • H donors: 0 H acceptors: 2 LogP: 3.47 Rotable bonds: 5
    Rule of 5 violations (Lipinski): 1
  • SMILES: CC(=O)O[C@H](CC[C@@H]1[C@@]2([C@@]1(C)C[C@H]1[C@@H](C2)OC(=O)C1=C)C)C
  • InChi: 1S/C18H26O4/c1-10(21-12(3)19)6-7-15-17(4)8-13-11(2)16(20)22-14(13)9-18(15,17)5/h10,13-15H,2,6-9H2,1,3-5H3/t10-,13+,14+,15-,17-,18+/m0/s1
  • InChiKey: USWATMHRMOTLRP-XUNGLMTJSA-N  


Substructure search Similarity search

Network

Hover on a compound node to display the structore

Synonyms

No synonyms found for this compound

Targets

Known targets for this compound

No curated genes were found associated with this compound

Predicted pathogen targets for this compound

By orthology
No druggable targets predicted by orthology data
By sequence similarity to non orthologous known druggable targets
No druggable targets predicted by sequence similarity
Obtained from network model

Ranking Plot

Putative Targets List

Species Potential target Raw Global Species
Echinococcus granulosus sodium leak channel non selective protein 0.0467 0.0276 0.0276
Trypanosoma cruzi phosphatidylinositol kinase related protein, putative 0.0478 0.0283 0.0801
Mycobacterium tuberculosis Probable cytochrome P450 monooxygenase 142 Cyp142 0.0067 0.0021 0.0113
Loa Loa (eye worm) hypothetical protein 0.0467 0.0276 0.1058
Loa Loa (eye worm) phosphatidylinositol 3 0.0264 0.0147 0.056
Brugia malayi Cytochrome P450 family protein 0.0087 0.0034 0.0124
Echinococcus granulosus transient receptor potential cation channel 0.0467 0.0276 0.0276
Schistosoma mansoni hypothetical protein 0.0094 0.0039 0.0394
Mycobacterium ulcerans cytochrome P450 185A4 Cyp185A4 0.0087 0.0034 0.0168
Echinococcus granulosus dual 3'5' cyclic AMP and GMP phosphodiesterase 0.0479 0.0283 0.0283
Brugia malayi Ulp1 protease family, C-terminal catalytic domain containing protein 0.0043 0.0006 0.0018
Leishmania major phosphatidylinositol 4-kinase, putative 0.0264 0.0147 0.0387
Loa Loa (eye worm) hypothetical protein 0.0051 0.0011 0.0038
Entamoeba histolytica hypothetical protein 0.0972 0.0597 0.7403
Toxoplasma gondii histone lysine-specific demethylase LSD1/BHC110/KDMA1A 0.0212 0.0114 0.1109
Trypanosoma brucei phosphatidylinositol 4-kinase, putative 0.0264 0.0147 0.1447
Brugia malayi Phosphatidylinositol 3- and 4-kinase family protein 0.0512 0.0305 0.1131
Trypanosoma brucei protein kinase, putative 0.1571 0.0979 1
Schistosoma mansoni netrin receptor unc5 0.0094 0.0039 0.0394
Schistosoma mansoni hypothetical protein 0.0524 0.0313 0.3194
Schistosoma mansoni voltage-gated potassium channel 0.0467 0.0276 0.282
Mycobacterium tuberculosis Probable fatty-acid-CoA ligase FadD2 (fatty-acid-CoA synthetase) (fatty-acid-CoA synthase) 0.0051 0.0011 0.0054
Leishmania major phosphatidylinositol kinase, putative 0.0264 0.0147 0.0387
Echinococcus multilocularis voltage gated hydrogen channel 1 0.0467 0.0276 0.0276
Mycobacterium tuberculosis Probable cytochrome P450 139 Cyp139 0.0067 0.0021 0.0113
Trypanosoma cruzi UDP-galactopyranose mutase 0.021 0.0113 0.0308
Trypanosoma cruzi cAMP specific phosphodiesterase, putative 0.0479 0.0283 0.0801
Trypanosoma cruzi cytochrome P450, putative 0.0087 0.0034 0.0082
Schistosoma mansoni cyclic-nucleotide-gated cation channel 0.0478 0.0283 0.2889
Mycobacterium ulcerans hypothetical protein 0.0051 0.0011 0.0044
Mycobacterium tuberculosis Probable lipase LipD 0.0108 0.0048 0.0265
Brugia malayi beta-lactamase 0.0108 0.0048 0.0174
Trypanosoma cruzi hypothetical protein, conserved 0.0133 0.0063 0.0166
Echinococcus multilocularis epidermal growth factor receptor 0.0709 0.043 0.043
Plasmodium falciparum GAF domain-related protein, putative 0.0345 0.0199 0.914
Brugia malayi Uncoordinated protein 44 0.0094 0.0039 0.014
Loa Loa (eye worm) hypothetical protein 0.021 0.0113 0.0429
Echinococcus multilocularis atpase aaa+ type core atpase aaa type core 0.1736 0.1084 0.1084
Brugia malayi Phosphatidylinositol 3- and 4-kinase family protein 0.0264 0.0147 0.0542
Loa Loa (eye worm) hypothetical protein 0.0467 0.0276 0.1058
Trypanosoma brucei Voltage-dependent calcium channel subunit, putative 0.0467 0.0276 0.2777
Schistosoma mansoni family C48 unassigned peptidase (C48 family) 0.0043 0.0006 0.006
Plasmodium falciparum 3',5'-cyclic nucleotide phosphodiesterase, putative 0.0133 0.0063 0.2834
Brugia malayi 3'5'-cyclic nucleotide phosphodiesterase family protein 0.0133 0.0063 0.0233
Leishmania major 4-coumarate:coa ligase-like protein 0.0051 0.0011 0.0014
Trichomonas vaginalis CMGC family protein kinase 0.1571 0.0979 1
Brugia malayi ion channel NompC 0.0467 0.0276 0.1024
Echinococcus multilocularis voltage dependent calcium channel 0.0467 0.0276 0.0276
Trichomonas vaginalis high-affinity cGMP-specific 3,5-cyclic phosphodiesterase, putative 0.0479 0.0283 0.2852
Echinococcus multilocularis DNA dependent protein kinase catalytic subunit 1.5736 1 1
Trichomonas vaginalis PIKK family atypical protein kinase 0.0264 0.0147 0.1447
Brugia malayi 3'5'-cyclic nucleotide phosphodiesterase family protein 0.0479 0.0283 0.1052
Echinococcus multilocularis cAMP specific 3',5' cyclic phosphodiesterase 0.0133 0.0063 0.0063
Echinococcus multilocularis neuropeptide s receptor 0.0937 0.0576 0.0576
Mycobacterium ulcerans fructose-bisphosphate aldolase 0.0148 0.0073 0.0372
Entamoeba histolytica Ulp1 protease family, C-terminal catalytic domain containing protein 0.0043 0.0006 0.0044
Schistosoma mansoni cellular tumor antigen P53 0.0055 0.0013 0.0137
Toxoplasma gondii 3'5'-cyclic nucleotide phosphodiesterase domain-containing protein 0.0133 0.0063 0.0592
Loa Loa (eye worm) hypothetical protein 0.0109 0.0048 0.018
Schistosoma mansoni voltage-gated potassium channel 0.0467 0.0276 0.282
Echinococcus multilocularis voltage dependent L type calcium channel subunit 0.0467 0.0276 0.0276
Toxoplasma gondii hypothetical protein 0.0345 0.0199 0.198
Trichomonas vaginalis voltage and ligand gated potassium channel, putative 0.0074 0.0026 0.0205
Mycobacterium ulcerans protoporphyrinogen oxidase 0.021 0.0113 0.0585
Brugia malayi Voltage-gated potassium channel, Shaw-family (KCNC, Kv3-like) alpha-subunit 0.0467 0.0276 0.1024
Schistosoma mansoni family C48 unassigned peptidase (C48 family) 0.0043 0.0006 0.006
Loa Loa (eye worm) hypothetical protein 0.0467 0.0276 0.1058
Echinococcus multilocularis cyclic nucleotide gated cation channel 0.0478 0.0283 0.0283
Loa Loa (eye worm) hypothetical protein 0.4117 0.2601 1
Mycobacterium tuberculosis Probable cytochrome P450 138 Cyp138 0.0067 0.0021 0.0113
Echinococcus multilocularis calcium:calmodulin dependent 3',5' cyclic 0.0133 0.0063 0.0063
Trichomonas vaginalis conserved hypothetical protein 0.0788 0.0481 0.488
Schistosoma mansoni tyrosine kinase 0.0422 0.0247 0.2526
Leishmania major phosphatidylinositol 3-kinase, putative 0.0374 0.0217 0.0581
Toxoplasma gondii 3'5'-cyclic nucleotide phosphodiesterase domain-containing protein 0.0133 0.0063 0.0592
Echinococcus granulosus TRP transient receptor potential channel 0.0467 0.0276 0.0276
Plasmodium vivax protoporphyrinogen oxidase, putative 0.021 0.0113 0.5127
Schistosoma mansoni voltage-gated potassium channel 0.0467 0.0276 0.282
Plasmodium falciparum phosphatidylinositol 3- and 4-kinase, putative 0.0264 0.0147 0.6719
Trichomonas vaginalis cGMP-specific 3,5-cyclic phosphodiesterase, putative 0.0479 0.0283 0.2852
Echinococcus granulosus cyclic nucleotide gated cation channel alpha 3 0.0478 0.0283 0.0283
Loa Loa (eye worm) hypothetical protein 0.0711 0.0431 0.1655
Leishmania major UDP-galactopyranose mutase 0.021 0.0113 0.0294
Echinococcus multilocularis insulin receptor 0.0422 0.0247 0.0247
Echinococcus granulosus serine:threonine protein kinase SMG1 0.0711 0.0431 0.0431
Mycobacterium ulcerans cytochrome P450 140A5 Cyp140A5 0.0067 0.0021 0.0098
Loa Loa (eye worm) voltage-gated calcium channel 0.0467 0.0276 0.1058
Trichomonas vaginalis rod cGMP-specific 3,5-cyclic phosphodiesterase, putative 0.0479 0.0283 0.2852
Echinococcus multilocularis tumor necrosis factor receptor superfamily 0.0144 0.007 0.007
Echinococcus granulosus sentrin specific protease 8 0.0102 0.0044 0.0044
Onchocerca volvulus 0.0048 0.0009 0.0117
Trichomonas vaginalis PIKK family atypical protein kinase 0.075 0.0456 0.4631
Giardia lamblia Phosphatidylinositol 4-kinase 0.0264 0.0147 0.1447
Leishmania major target of rapamycin (TOR) kinase 2, putative 0.13 0.0806 0.2203
Schistosoma mansoni cyclic-nucleotide-gated cation channel 0.0467 0.0276 0.282
Schistosoma mansoni cytochrome P450 0.0067 0.0021 0.0216
Schistosoma mansoni hypothetical protein 0.0045 0.0007 0.0075
Schistosoma mansoni voltage-gated potassium channel 0.0467 0.0276 0.282
Loa Loa (eye worm) hypothetical protein 0.0038 0.0003 0.0007
Brugia malayi Probable 3',5'-cyclic phosphodiesterase C32E12.2, putative 0.425 0.2685 1
Mycobacterium leprae putative cytochrome p450 0.0067 0.0021 0.0543
Chlamydia trachomatis deubiquitinase/deneddylase Dub1 0.0043 0.0006 0.0284
Loa Loa (eye worm) hypothetical protein 0.0531 0.0317 0.1214
Plasmodium vivax phosphatidylinositol 3- and 4-kinase, putative 0.0264 0.0147 0.6719
Plasmodium vivax sentrin-specific protease 1, putative 0.0043 0.0006 0.0146
Echinococcus multilocularis beta LACTamase domain containing family member 0.0108 0.0048 0.0048
Trichomonas vaginalis phosphatidylinositol 3-kinase class, putative 0.0898 0.0551 0.56
Schistosoma mansoni hyperpolarization activated cyclic nucleotide-gated potassium channel 0.0478 0.0283 0.2889
Entamoeba histolytica Phosphatidylinositol 3- and 4-kinase family 0.0734 0.0446 0.5519
Trypanosoma cruzi phosphatidylinositol kinase related protein, putative 0.0295 0.0167 0.0464
Toxoplasma gondii hypothetical protein 0.0467 0.0276 0.2777
Echinococcus multilocularis mitogen activated protein kinase 3 0.1571 0.0979 0.0979
Trypanosoma cruzi hypothetical protein, conserved 0.0133 0.0063 0.0166
Onchocerca volvulus 0.0055 0.0013 0.028
Plasmodium vivax lysine-specific histone demethylase 1, putative 0.021 0.0113 0.5127
Mycobacterium ulcerans cytochrome P450 187A5 Cyp187A5 0.0067 0.0021 0.0098
Leishmania major lanosterol 14-alpha-demethylase, putative 0.0067 0.0021 0.0042
Schistosoma mansoni retinoblastoma-binding protein 4 (rbbp4) 0.0094 0.0039 0.0394
Mycobacterium ulcerans two component sensor histidine kinase DevS 0.0345 0.0199 0.1042
Echinococcus multilocularis TNFR CD27 30 40 95 cysteine rich region 0.0144 0.007 0.007
Mycobacterium ulcerans cytochrome P450 187A4 Cyp187A4 0.0067 0.0021 0.0098
Schistosoma mansoni hyperpolarization activated cyclic nucleotide-gated potassium channel 0.0467 0.0276 0.282
Mycobacterium tuberculosis Probable esterase LipL 0.0108 0.0048 0.0265
Trypanosoma cruzi phosphatidylinositol 4-kinase alpha, putative 0.0374 0.0217 0.0609
Echinococcus multilocularis voltage dependent calcium channel 0.0467 0.0276 0.0276
Trypanosoma cruzi phosphatidylinositol 3-related kinase, putative 0.1344 0.0834 0.239
Entamoeba histolytica phosphatidylinositol 3-kinase, putative 0.0512 0.0305 0.3761
Brugia malayi Ulp1 protease family, C-terminal catalytic domain containing protein 0.0043 0.0006 0.0018
Trypanosoma cruzi cAMP-specific phosphodiesterase, putative 0.0133 0.0063 0.0166
Trichomonas vaginalis cGMP-dependent 3,5-cyclic phosphodiesterase, putative 0.0479 0.0283 0.2852
Echinococcus granulosus phosphatidylinositol 3 and 4 kinase 0.1344 0.0834 0.0834
Loa Loa (eye worm) beta-lactamase 0.0108 0.0048 0.0179
Chlamydia trachomatis deubiquitinase/deneddylase Dub2 0.0043 0.0006 0.0284
Leishmania major target of rapamycin (TOR) kinase 1, putative 0.13 0.0806 0.2203
Trichomonas vaginalis PIKK family atypical protein kinase 0.1275 0.079 0.8065
Onchocerca volvulus Transient receptor potential cation channel trpm homolog 0.0467 0.0276 1
Brugia malayi Cytochrome P450 family protein 0.0234 0.0127 0.0471
Toxoplasma gondii histone lysine-specific demethylase 0.021 0.0113 0.1097
Trichomonas vaginalis PIKK family atypical protein kinase 0.1235 0.0765 0.7806
Mycobacterium tuberculosis Possible conserved lipoprotein LpqK 0.0108 0.0048 0.0265
Trypanosoma cruzi mitogen activated protein kinase 4, putative 0.1571 0.0979 0.2807
Loa Loa (eye worm) transcription factor SMAD2 0.0123 0.0057 0.0216
Brugia malayi Voltage-gated potassium channel, Shaw-family (KCNC, Kv3-like) alpha-subunit. C. elegans egl-36 ortholog 0.0467 0.0276 0.1024
Schistosoma mansoni tyrosine kinase 0.0422 0.0247 0.2526
Plasmodium falciparum dipeptidyl aminopeptidase 3 0.0085 0.0033 0.1408
Echinococcus multilocularis shaker cognate 0.0467 0.0276 0.0276
Echinococcus granulosus p2X purinoceptor 4 0.0076 0.0027 0.0027
Echinococcus multilocularis transient receptor potential cation channel 0.0467 0.0276 0.0276
Mycobacterium ulcerans cytochrome P450 126A3 Cyp126A3 0.0067 0.0021 0.0098
Echinococcus multilocularis protoporphyrinogen oxidase 0.021 0.0113 0.0113
Toxoplasma gondii phosphatidylinositol 3- and 4-kinase 0.0374 0.0217 0.2169
Echinococcus granulosus ryanodine receptor 44f 0.0467 0.0276 0.0276
Trichomonas vaginalis phosphatidylinositol 3-kinase class, putative 0.0374 0.0217 0.2169
Trichomonas vaginalis calcium/calmodulin-dependent 3,5-cyclic nucleotide phosphodiesterase, putative 0.0479 0.0283 0.2852
Schistosoma mansoni Protoporphyrinogen oxidase chloroplast/mitochondrial precursor 0.021 0.0113 0.115
Schistosoma mansoni two-pore calcium channel 0.0467 0.0276 0.282
Echinococcus granulosus cyclic nucleotide gated cation channel 0.0478 0.0283 0.0283
Brugia malayi SWIRM domain containing protein 0.021 0.0113 0.0415
Loa Loa (eye worm) Ulp1 protease 0.0043 0.0006 0.0019
Trichomonas vaginalis calcium/calmodulin-dependent 3',5'-cyclic nucleotide phosphodiesterase, putative 0.0133 0.0063 0.0592
Trypanosoma cruzi phosphatidylinositol 3-kinase, putative 0.0248 0.0137 0.0377
Trichomonas vaginalis penicillin-binding protein, putative 0.0108 0.0048 0.043
Schistosoma mansoni tyrosine kinase 0.0702 0.0426 0.4347
Mycobacterium ulcerans cytochrome P450 123A3 Cyp123A3 0.0067 0.0021 0.0098
Trichomonas vaginalis cAMP-specific phosphodiesterase, putative 0.0133 0.0063 0.0592
Brugia malayi phosphoinositide 3'-hydroxykinase p110-alpha subunit, putative 0.0371 0.0215 0.0797
Brugia malayi beta-lactamase family protein 0.0108 0.0048 0.0174
Onchocerca volvulus 0.021 0.0113 0.3949
Loa Loa (eye worm) hypothetical protein 0.0467 0.0276 0.1058
Mycobacterium tuberculosis Probable epoxide hydrolase EphA (epoxide hydratase) (arene-oxide hydratase) 0.016 0.0081 0.0453
Trichomonas vaginalis Clan CE, family C48, Ulp1-like cysteine peptidase 0.0102 0.0044 0.0387
Trichomonas vaginalis PIKK family atypical protein kinase 0.128 0.0794 0.8097
Echinococcus granulosus tumor necrosis factor receptor superfamily 0.0144 0.007 0.007
Loa Loa (eye worm) CYP4Cod1 0.0087 0.0034 0.0128
Schistosoma mansoni cgmp-dependent 35-cyclic phosphodiesterase 0.0479 0.0283 0.2895
Schistosoma mansoni hypothetical protein 0.0067 0.0021 0.0216
Brugia malayi Voltage-gated calcium channel, alpha subunit 0.0467 0.0276 0.1024
Onchocerca volvulus Netrin receptor homolog 0.0094 0.0039 0.121
Mycobacterium ulcerans cytochrome P450 142A3 Cyp142A3 0.0067 0.0021 0.0098
Brugia malayi Transient-receptor-potential like protein 0.0467 0.0276 0.1024
Schistosoma mansoni camp-specific 35-cyclic phosphodiesterase 0.0133 0.0063 0.0648
Echinococcus granulosus sodium channel protein 0.3467 0.2186 0.2186
Trypanosoma cruzi cytochrome p450-like protein, putative 0.0067 0.0021 0.0044
Plasmodium falciparum cGMP-specific phosphodiesterase 0.0133 0.0063 0.2834
Trichomonas vaginalis phosphatidylinositol kinase, putative 0.111 0.0685 0.6983
Toxoplasma gondii 3'5'-cyclic nucleotide phosphodiesterase domain-containing protein 0.0133 0.0063 0.0592
Trichomonas vaginalis high-affinity cGMP-specific 3,5-cyclic phosphodiesterase, putative 0.0133 0.0063 0.0592
Trypanosoma brucei cAMP-specific phosphodiesterase 0.0479 0.0283 0.2852
Mycobacterium ulcerans lipase LipD 0.0108 0.0048 0.0239
Trichomonas vaginalis phosphatidylinositol 3-kinase catalytic subunit gamma, putative 0.111 0.0685 0.6983
Echinococcus granulosus sentrin specific protease 1 0.0043 0.0006 0.0006
Trichomonas vaginalis conserved hypothetical protein 0.0447 0.0263 0.2646
Plasmodium vivax hypothetical protein, conserved 0.0264 0.0147 0.6719
Mycobacterium tuberculosis Fatty-acid-AMP ligase FadD30 (fatty-acid-AMP synthetase) (fatty-acid-AMP synthase) 0.0038 0.0003 0.0008
Trichomonas vaginalis PIKK family atypical protein kinase 0.0264 0.0147 0.1447
Schistosoma mansoni inositol 145-trisphosphate receptor 0.0467 0.0276 0.282
Echinococcus granulosus voltage gated potassium channel 0.0485 0.0287 0.0287
Echinococcus multilocularis voltage dependent calcium channel type d subunit 0.0467 0.0276 0.0276
Toxoplasma gondii hypothetical protein 0.0345 0.0199 0.198
Loa Loa (eye worm) hypothetical protein 0.0264 0.0147 0.056
Loa Loa (eye worm) hypothetical protein 0.0108 0.0048 0.0179
Brugia malayi MAP kinase sur-1 0.1571 0.0979 0.3642
Trypanosoma cruzi hypothetical protein, conserved 0.0133 0.0063 0.0166
Trichomonas vaginalis Sentrin-specific protease, putative 0.0102 0.0044 0.0387
Echinococcus multilocularis voltage dependent L type calcium channel subunit 0.0467 0.0276 0.0276
Plasmodium vivax dipeptidyl aminopeptidase 3, putative 0.0085 0.0033 0.1408
Trichomonas vaginalis PIKK family atypical protein kinase 0.1255 0.0778 0.7936
Loa Loa (eye worm) hypothetical protein 0.021 0.0113 0.0429
Schistosoma mansoni hypothetical protein 0.0467 0.0276 0.282
Loa Loa (eye worm) hypothetical protein 0.0386 0.0225 0.086
Schistosoma mansoni P2X receptor subunit 0.0076 0.0027 0.0277
Schistosoma mansoni voltage-gated potassium channel 0.0485 0.0287 0.2936
Trichomonas vaginalis fructose-bisphosphate aldolase, putative 0.0302 0.0171 0.1698
Mycobacterium ulcerans putative regulatory protein 0.0345 0.0199 0.1042
Schistosoma mansoni calcium-activated potassium channel 0.0467 0.0276 0.282
Leishmania major cytochrome p450-like protein 0.0067 0.0021 0.0042
Trypanosoma brucei phosphatidylinositol 3-kinase catalytic subunit, putative 0.0264 0.0147 0.1447
Mycobacterium tuberculosis Probable cytochrome P450 123 Cyp123 0.0067 0.0021 0.0113
Mycobacterium ulcerans cytochrome P450 191A3 Cyp191A3 0.0067 0.0021 0.0098
Schistosoma mansoni transient receptor potential cation channel subfamily m member 0.0467 0.0276 0.282
Trypanosoma cruzi phosphatidylinositol kinase, putative 0.0264 0.0147 0.0406
Echinococcus multilocularis transfer RNA-Gly 0.0467 0.0276 0.0276
Loa Loa (eye worm) phosphatidylinositol kinase 0.0264 0.0147 0.056
Brugia malayi cytochrome P450 0.0067 0.0021 0.0075
Echinococcus multilocularis voltage dependent calcium channel type d subunit 0.0467 0.0276 0.0276
Trichomonas vaginalis conserved hypothetical protein 0.0479 0.0283 0.2852
Plasmodium vivax 3',5'-cyclic nucleotide phosphodiesterase, putative 0.0133 0.0063 0.2834
Brugia malayi MH2 domain containing protein 0.0123 0.0057 0.0209
Loa Loa (eye worm) voltage and ligand gated potassium channel 0.0541 0.0323 0.124
Trypanosoma brucei cAMP-specific phosphodiesterase, putative 0.0133 0.0063 0.0592
Trypanosoma cruzi cAMP phosphodiesterase A, putative 0.0133 0.0063 0.0166
Plasmodium vivax phosphatidylinositol 3-kinase, putative 0.0374 0.0217 1
Echinococcus multilocularis potassium voltage gated channel subfamily H 0.0485 0.0287 0.0287
Echinococcus granulosus Potassium voltage gated channel protein Shaw 0.0467 0.0276 0.0276
Loa Loa (eye worm) hypothetical protein 0.0467 0.0276 0.1058
Onchocerca volvulus 0.0108 0.0048 0.1547
Schistosoma mansoni transient receptor potential cation channel subfamily m member 0.0467 0.0276 0.282
Echinococcus multilocularis phosphatidylinositol 4,5 bisphosphate 3 kinase 0.1481 0.0922 0.0922
Brugia malayi beta-lactamase family protein 0.0108 0.0048 0.0174
Trichomonas vaginalis PIKK family atypical protein kinase 0.1255 0.0778 0.7936
Trichomonas vaginalis cAMP-specific 3,5-cyclic phosphodiesterase, putative 0.0479 0.0283 0.2852
Echinococcus granulosus neuropeptide receptor A26 0.0937 0.0576 0.0576
Mycobacterium ulcerans acyl-CoA synthetase 0.0051 0.0011 0.0044
Mycobacterium tuberculosis Conserved hypothetical protein 0.0264 0.0147 0.0832
Trichomonas vaginalis PIKK family atypical protein kinase 0.075 0.0456 0.4631
Giardia lamblia hypothetical protein 0.0133 0.0063 0.0592
Trichomonas vaginalis calcium/calmodulin-dependent 3,5-cyclic nucleotide phosphodiesterase, putative 0.0479 0.0283 0.2852
Schistosoma mansoni phosphatidylinositol-45-bisphosphate 3-kinase catalytic subunit alpha PI3K 0.1481 0.0922 0.9417
Brugia malayi FAT domain containing protein 0.0524 0.0313 0.1161
Schistosoma mansoni hypothetical protein 0.0264 0.0147 0.1498
Schistosoma mansoni phosphatidylinositol 4-kinase 0.0264 0.0147 0.1498
Echinococcus multilocularis transient receptor potential cation channel 0.0467 0.0276 0.0276
Echinococcus multilocularis sentrin specific protease 8 0.0102 0.0044 0.0044
Schistosoma mansoni hypothetical protein 0.0048 0.0009 0.0092
Mycobacterium tuberculosis Probable flavin-containing monoamine oxidase AofH (amine oxidase) (MAO) 0.2776 0.1747 1
Trypanosoma cruzi cAMP specific phosphodiesterase, putative 0.0479 0.0283 0.0801
Echinococcus multilocularis transient receptor potential cation channel 0.0467 0.0276 0.0276
Trichomonas vaginalis high-affinity cGMP-specific 3,5-cyclic phosphodiesterase, putative 0.0479 0.0283 0.2852
Trichomonas vaginalis PIKK family atypical protein kinase 0.1275 0.079 0.8065
Leishmania major hypothetical protein, conserved 0.0133 0.0063 0.0158
Mycobacterium tuberculosis Probable cytochrome P450 143 Cyp143 0.0067 0.0021 0.0113
Mycobacterium tuberculosis Probable cytochrome P450 137 Cyp137 0.0067 0.0021 0.0113
Trypanosoma cruzi phosphatidylinositol 3-kinase 2, putative 0.111 0.0685 0.196
Echinococcus granulosus cyclic nucleotide gated cation channel 0.0478 0.0283 0.0283
Echinococcus granulosus calcium:calmodulin dependent 3'5' cyclic 0.0133 0.0063 0.0063
Loa Loa (eye worm) hypothetical protein 0.0467 0.0276 0.1058
Trypanosoma brucei phosphatidylinositol 3-kinase, putative 0.0512 0.0305 0.3071
Mycobacterium ulcerans cytochrome P450 51B1 Cyp51B1 0.0067 0.0021 0.0098
Entamoeba histolytica phosphatidylinositol-4,5-bisphosphate 3-kinase, putative 0.0374 0.0217 0.267
Trypanosoma cruzi hypothetical protein, conserved 0.0108 0.0048 0.0121
Brugia malayi cation channel family protein 0.0467 0.0276 0.1024
Echinococcus multilocularis potassium voltage gated channel protein 0.0467 0.0276 0.0276
Echinococcus multilocularis PIK kinase, FAT and Armadillo domain containing protein 0.0524 0.0313 0.0313
Echinococcus granulosus p2X purinoceptor 4 0.0076 0.0027 0.0027
Trypanosoma cruzi Voltage-dependent calcium channel subunit, putative 0.0467 0.0276 0.078
Loa Loa (eye worm) hypothetical protein 0.0051 0.0011 0.0038
Schistosoma mansoni P2X receptor subunit 0.0076 0.0027 0.0277
Giardia lamblia GTOR 0.13 0.0806 0.8227
Trichomonas vaginalis PIKK family atypical protein kinase 0.1275 0.079 0.8065
Echinococcus multilocularis expressed conserved protein 0.0102 0.0044 0.0044
Echinococcus multilocularis Ankyrin 0.0094 0.0039 0.0039
Entamoeba histolytica acyl-coA synthetase, putative 0.0051 0.0011 0.0107
Echinococcus multilocularis cAMP and cAMP inhibited cGMP 3',5' cyclic 0.425 0.2685 0.2685
Echinococcus granulosus expressed conserved protein 0.0102 0.0044 0.0044
Brugia malayi Voltage-gated potassium channel, Shab-family (KCNB, Kv2-like) alpha-subunit 0.0467 0.0276 0.1024
Schistosoma mansoni dipeptidyl-peptidase I (C01 family) 0.0217 0.0117 0.1195
Trichomonas vaginalis PIKK family atypical protein kinase 0.128 0.0794 0.8097
Plasmodium falciparum dipeptidyl aminopeptidase 2 0.0217 0.0117 0.5332
Echinococcus multilocularis 0.0067 0.0021 0.0021
Loa Loa (eye worm) hypothetical protein 0.0043 0.0006 0.0019
Trichomonas vaginalis cGMP-inhibited 3,5-cyclic phosphodiesterase, putative 0.0479 0.0283 0.2852
Loa Loa (eye worm) hypothetical protein 0.0467 0.0276 0.1058
Mycobacterium tuberculosis Conserved protein 0.0108 0.0048 0.0265
Trypanosoma brucei Phosphatidylinositol 3-kinase tor1 0.13 0.0806 0.8227
Brugia malayi Phosphatidylinositol 3- and 4-kinase family protein 0.0264 0.0147 0.0542
Schistosoma mansoni voltage-gated ion channel 0.0467 0.0276 0.282
Echinococcus granulosus voltage gated hydrogen channel 1 0.0467 0.0276 0.0276
Giardia lamblia Hypothetical protein 0.0264 0.0147 0.1447
Mycobacterium tuberculosis Two component sensor histidine kinase DosT 0.0345 0.0199 0.1129
Echinococcus granulosus FKBP12 rapamycin complex associated protein 0.13 0.0806 0.0806
Toxoplasma gondii 3'5'-cyclic nucleotide phosphodiesterase domain-containing protein 0.0133 0.0063 0.0592
Echinococcus multilocularis potassium large conductance calcium activated 0.0467 0.0276 0.0276
Echinococcus multilocularis potassium:sodium hyperpolarization activated 0.0478 0.0283 0.0283
Leishmania major cAMP phosphodiesterase A, putative;with=GeneDB:LinJ18_V3.1100 0.0133 0.0063 0.0158
Echinococcus granulosus phosphatidylinositol 3 kinase catalytic subunit 0.0374 0.0217 0.0217
Trypanosoma brucei cAMP-specific phosphodiesterase 0.0479 0.0283 0.2852
Giardia lamblia Encystation-specific protease 0.0085 0.0033 0.0278
Mycobacterium tuberculosis Probable cytochrome P450 136 Cyp136 0.0067 0.0021 0.0113
Echinococcus multilocularis high affinity cAMP specific 3',5' cyclic 0.0133 0.0063 0.0063
Schistosoma mansoni tyrosine kinase 0.0702 0.0426 0.4347
Trichomonas vaginalis calcium/calmodulin-dependent 3,5-cyclic nucleotide phosphodiesterase, putative 0.0479 0.0283 0.2852
Mycobacterium tuberculosis Probable chain -fatty-acid-CoA ligase FadD13 (fatty-acyl-CoA synthetase) 0.0051 0.0011 0.0054
Toxoplasma gondii non-specific serine/threonine protein kinase 0.0788 0.0481 0.488
Loa Loa (eye worm) hypothetical protein 0.0467 0.0276 0.1058
Echinococcus multilocularis short transient receptor potential channel 6 0.0467 0.0276 0.0276
Trypanosoma brucei target of rapamycin kinase 3, putative 0.128 0.0794 0.8098
Schistosoma mansoni high-affinity cgmp-specific 35-cyclic phosphodiesterase 0.0133 0.0063 0.0648
Schistosoma mansoni high voltage-activated calcium channel Cav2A 0.0467 0.0276 0.282
Leishmania major 4-coumarate:coa ligase-like protein 0.0051 0.0011 0.0014
Schistosoma mansoni transient receptor potential channel 4 0.0467 0.0276 0.282
Echinococcus granulosus voltage gated potassium channel 0.0467 0.0276 0.0276
Loa Loa (eye worm) hypothetical protein 0.0133 0.0063 0.024
Loa Loa (eye worm) ryanodine receptor 0.0467 0.0276 0.1058
Echinococcus multilocularis neuropeptide receptor A26 0.0937 0.0576 0.0576
Trichomonas vaginalis PIKK family atypical protein kinase 0.1235 0.0765 0.7806
Leishmania major target of rapamycin kinase (TOR) kinase 3 0.128 0.0794 0.2168
Entamoeba histolytica fructose-1,6-bisphosphate aldolase, putative 0.0302 0.0171 0.2099
Echinococcus granulosus potassium:sodium hyperpolarization activated 0.0478 0.0283 0.0283
Brugia malayi hypothetical protein 0.021 0.0113 0.0415
Leishmania major hypothetical protein, conserved 0.0467 0.0276 0.0744
Entamoeba histolytica phosphatidylinositol 4-kinase, putative 0.0374 0.0217 0.267
Trichomonas vaginalis calcium/calmodulin-dependent 3,5-cyclic nucleotide phosphodiesterase, putative 0.0479 0.0283 0.2852
Trichomonas vaginalis D-aminoacylase, putative 0.0108 0.0048 0.043
Mycobacterium ulcerans cytochrome P450 108B4 Cyp108B4 0.0067 0.0021 0.0098
Mycobacterium tuberculosis Probable cytochrome P450 125 Cyp125 0.0067 0.0021 0.0113
Trichomonas vaginalis cyclic nucleotide phosphodiesterase, putative 0.0479 0.0283 0.2852
Onchocerca volvulus 0.0051 0.0011 0.0187
Leishmania major mitogen activated protein kinase, putative,map kinase, putative 0.1571 0.0979 0.2677
Entamoeba histolytica protein kinase rad3, putative 0.0711 0.0431 0.5336
Brugia malayi olfactory channel protein osm-9 0.0467 0.0276 0.1024
Trichomonas vaginalis conserved hypothetical protein 0.0047 0.0008 0.0026
Trichomonas vaginalis esterase, putative 0.0108 0.0048 0.043
Schistosoma mansoni phosphatidylinositol 3-and 4-kinase 0.1344 0.0834 0.8524
Trypanosoma cruzi mitogen-activated protein kinase 11, putative 0.1571 0.0979 0.2807
Trypanosoma brucei phosphatidylinositol 3-kinase, putative 0.1235 0.0765 0.7806
Mycobacterium ulcerans acyl-CoA synthetase 0.0051 0.0011 0.0044
Echinococcus granulosus Protein patched homolog 1 0.0047 0.0008 0.0008
Mycobacterium ulcerans cytochrome P450 144A4 Cyp144A4 0.0067 0.0021 0.0098
Schistosoma mansoni camp-specific 35-cyclic phosphodiesterase 0.0133 0.0063 0.0648
Trichomonas vaginalis PIKK family atypical protein kinase 0.128 0.0794 0.8097
Loa Loa (eye worm) hypothetical protein 0.0133 0.0063 0.024
Entamoeba histolytica phosphatidylinositol 3-kinase, putative 0.0972 0.0597 0.7403
Trichomonas vaginalis calcium/calmodulin-dependent 3,5-cyclic nucleotide phosphodiesterase, putative 0.0133 0.0063 0.0592
Onchocerca volvulus Transient receptor potential cation channel trpm homolog 0.0467 0.0276 1
Trichomonas vaginalis cGMP-inhibited 3,5-cyclic phosphodiesterase, putative 0.0133 0.0063 0.0592
Schistosoma mansoni voltage-gated potassium channel 0.0549 0.0328 0.3351
Leishmania major phosphatidylinositol kinase related protein, putative 0.0295 0.0167 0.0443
Brugia malayi Ulp1 protease family, C-terminal catalytic domain containing protein 0.0043 0.0006 0.0018
Loa Loa (eye worm) cytochrome P450 family protein 0.0087 0.0034 0.0128
Echinococcus multilocularis Niemann Pick C1 protein 0.0109 0.0048 0.0048
Echinococcus granulosus melanoma receptor tyrosine protein kinase 0.0709 0.043 0.043
Trichomonas vaginalis CMGC family protein kinase 0.1571 0.0979 1
Trichomonas vaginalis fructose-bisphosphate aldolase, putative 0.0302 0.0171 0.1698
Brugia malayi Phosphatidylinositol 3- and 4-kinase family protein 0.0723 0.0439 0.1632
Mycobacterium ulcerans monoamine oxidase 0.021 0.0113 0.0585
Trichomonas vaginalis cone cGMP-specific 3,5-cyclic phosphodiesterase, putative 0.0479 0.0283 0.2852
Echinococcus granulosus potassium large conductance calcium activated 0.0467 0.0276 0.0276
Schistosoma mansoni calcium/calmodulin-dependent 35-cyclic nucleotide phosphodiesterase 0.0133 0.0063 0.0648
Loa Loa (eye worm) hypothetical protein 0.0467 0.0276 0.1058
Echinococcus granulosus serine protein kinase ATM 0.0742 0.0451 0.0451
Mycobacterium leprae conserved hypothetical protein 0.0345 0.0199 1
Loa Loa (eye worm) phosphatidylinositol 3 0.0264 0.0147 0.056
Schistosoma mansoni phosphatidylinositol 4-kinase type-II 0.0264 0.0147 0.1498
Brugia malayi Voltage-gated potassium channel, Shaw-family (KCNC, Kv3-like) alpha-subunit 0.0467 0.0276 0.1024
Echinococcus granulosus voltage dependent calcium channel 0.0467 0.0276 0.0276
Echinococcus granulosus two pore calcium channel protein 1 0.0467 0.0276 0.0276
Mycobacterium tuberculosis Probable lipase LipE 0.0108 0.0048 0.0265
Plasmodium falciparum phosphatidylinositol 3-kinase 0.0374 0.0217 1
Loa Loa (eye worm) hypothetical protein 0.3772 0.2381 0.9154
Entamoeba histolytica phosphatidylinositol 3-kinase, putative 0.0586 0.0351 0.4343
Echinococcus multilocularis potassium voltage gated channel subfamily D 0.0467 0.0276 0.0276
Toxoplasma gondii 3'5'-cyclic nucleotide phosphodiesterase domain-containing protein 0.0133 0.0063 0.0592
Giardia lamblia Fructose-bisphosphate aldolase 0.0302 0.0171 0.1698
Brugia malayi Voltage-gated calcium channel, T-type, alpha subunit. C. elegans cca-1 ortholog 0.0467 0.0276 0.1024
Trichomonas vaginalis cAMP and cAMP-inhibited cGMP 3,5-cyclic phosphodiesterase, putative 0.0133 0.0063 0.0592
Echinococcus granulosus transient receptor potential gamma protein 0.0467 0.0276 0.0276
Brugia malayi Niemann-Pick C1 protein precursor 0.0109 0.0048 0.0175
Toxoplasma gondii 3'5'-cyclic nucleotide phosphodiesterase domain-containing protein 0.0133 0.0063 0.0592
Loa Loa (eye worm) beta-LACTamase domain containing family member 0.0108 0.0048 0.0179
Schistosoma mansoni phosphatidylinositol 3-kinase class 0.0264 0.0147 0.1498
Brugia malayi Corticotropin releasing factor receptor 2 precursor, putative 0.0052 0.0011 0.0039
Schistosoma mansoni voltage-gated potassium channel 0.0467 0.0276 0.282
Trichomonas vaginalis cGMP-specific 3,5-cyclic phosphodiesterase, putative 0.0479 0.0283 0.2852
Onchocerca volvulus 0.0467 0.0276 1
Plasmodium vivax hypothetical protein, conserved 0.0345 0.0199 0.914
Echinococcus multilocularis sentrin specific protease 7 0.0192 0.0101 0.0101
Schistosoma mansoni family C48 unassigned peptidase (C48 family) 0.0192 0.0101 0.103
Trichomonas vaginalis calcium/calmodulin-dependent 3,5-cyclic nucleotide phosphodiesterase, putative 0.0479 0.0283 0.2852
Schistosoma mansoni family S12 unassigned peptidase (S12 family) 0.0108 0.0048 0.0487
Echinococcus granulosus potassium voltage gated channel protein 0.0467 0.0276 0.0276
Entamoeba histolytica Ulp1 protease family, C-terminal catalytic domain containing protein 0.0192 0.0101 0.1226
Echinococcus granulosus calcium activated potassium channel 0.0481 0.0285 0.0285
Echinococcus multilocularis potassium voltage gated channel subfamily D 0.0467 0.0276 0.0276
Loa Loa (eye worm) hypothetical protein 0.0467 0.0276 0.1058
Echinococcus multilocularis protein dispatched 1 0.0053 0.0013 0.0013
Echinococcus granulosus lysine specific histone demethylase 1A 0.021 0.0113 0.0113
Echinococcus multilocularis calcium:calmodulin dependent 3',5' cyclic 0.0133 0.0063 0.0063
Schistosoma mansoni voltage-gated potassium channel 0.0467 0.0276 0.282
Toxoplasma gondii GAF domain-containing protein 0.0345 0.0199 0.198
Schistosoma mansoni transient receptor potential channel 0.0467 0.0276 0.282
Echinococcus granulosus potassium channel KvQLT family member kqt 1 0.0467 0.0276 0.0276
Echinococcus granulosus sterol regulatory element binding protein 0.0047 0.0008 0.0008
Leishmania major calcium channel protein, putative,ion transporter, putative 0.3467 0.2186 0.6
Schistosoma mansoni mixed-lineage leukemia protein mll 0.0067 0.0022 0.022
Schistosoma mansoni amine oxidase 0.021 0.0113 0.115
Trypanosoma brucei phosphatidylinositol 4-kinase, putative 0.13 0.0806 0.8227
Toxoplasma gondii FATC domain-containing protein 0.0742 0.0451 0.4579
Mycobacterium ulcerans cytochrome P450 189A7 Cyp189A7 0.0067 0.0021 0.0098
Mycobacterium tuberculosis Probable cytochrome P450 130 Cyp130 0.0067 0.0021 0.0113
Leishmania major phosphatidylinositol 3-kinase, putative 0.1235 0.0765 0.209
Trypanosoma brucei phosphatidylinositol 4-kinase alpha, putative 0.0374 0.0217 0.2169
Echinococcus multilocularis high affinity cgmp specific 3' 5' cyclic 0.0133 0.0063 0.0063
Mycobacterium tuberculosis Conserved protein 0.0108 0.0048 0.0265
Trichomonas vaginalis PIKK family atypical protein kinase 0.0742 0.0451 0.4579
Mycobacterium tuberculosis Probable cytochrome P450 141 Cyp141 0.0067 0.0021 0.0113
Schistosoma mansoni voltage-gated potassium channel 0.0467 0.0276 0.282
Echinococcus granulosus cAMP specific 3'5' cyclic phosphodiesterase 0.0133 0.0063 0.0063
Loa Loa (eye worm) hypothetical protein 0.0043 0.0006 0.0019
Toxoplasma gondii ABC1 family protein 0.0108 0.0048 0.043
Schistosoma mansoni voltage-gated potassium channel 0.0478 0.0283 0.2889
Loa Loa (eye worm) TK/EGFR protein kinase 0.132 0.0819 0.3147
Toxoplasma gondii hypothetical protein 0.0467 0.0276 0.2777
Mycobacterium ulcerans long-chain-fatty-acid--CoA ligase 0.0051 0.0011 0.0044
Trichomonas vaginalis conserved hypothetical protein 0.0345 0.0199 0.198
Mycobacterium tuberculosis Probable cytochrome P450 144 Cyp144 0.0067 0.0021 0.0113
Echinococcus granulosus hyperpolarization activated cyclic 0.0478 0.0283 0.0283
Toxoplasma gondii histone lysine methyltransferase SET1 0.006 0.0017 0.0114
Echinococcus multilocularis transient receptor potential gamma protein 0.0467 0.0276 0.0276
Brugia malayi AMP-binding enzyme family protein 0.0051 0.0011 0.0037
Echinococcus granulosus Basic leucine zipper bZIP transcription 0.0037 0.0002 0.0002
Brugia malayi Iron-sulfur cluster assembly accessory protein 0.0048 0.0009 0.003
Trichomonas vaginalis penicillin-binding protein, putative 0.0108 0.0048 0.043
Mycobacterium tuberculosis Probable cytochrome P450 132 Cyp132 0.0067 0.0021 0.0113
Onchocerca volvulus 0.0108 0.0048 0.1547
Trichomonas vaginalis PIKK family atypical protein kinase 0.128 0.0794 0.8097
Trichomonas vaginalis phopsphatidylinositol 3-kinase, drosophila, putative 0.0264 0.0147 0.1447
Schistosoma mansoni hypothetical protein 0.0179 0.0092 0.0943
Leishmania major hypothetical protein, unknown function 0.0467 0.0276 0.0744
Trichomonas vaginalis PIKK family atypical protein kinase 0.1255 0.0778 0.7936
Echinococcus multilocularis Zinc finger, PHD finger 0.0374 0.0217 0.0217
Schistosoma mansoni phosphatidylinositol 4-kinase 0.0374 0.0217 0.2216
Mycobacterium ulcerans hypothetical protein 0.0108 0.0048 0.0239
Echinococcus multilocularis serine protein kinase ATM 0.0742 0.0451 0.0451
Brugia malayi Furin-like cysteine rich region family protein 0.132 0.0819 0.3048
Schistosoma mansoni hypothetical protein 0.0045 0.0007 0.0075
Leishmania major cAMP-specific phosphodiesterase, putative 0.0133 0.0063 0.0158
Trypanosoma cruzi cytochrome P450, putative 0.0087 0.0034 0.0082
Trypanosoma cruzi hypothetical protein, conserved 0.0133 0.0063 0.0166
Trypanosoma cruzi hypothetical protein 0.0102 0.0044 0.0109
Echinococcus multilocularis ryanodine receptor 44f 0.0467 0.0276 0.0276
Entamoeba histolytica hypothetical protein 0.0264 0.0147 0.1796
Trichomonas vaginalis CMGC family protein kinase 0.1571 0.0979 1
Toxoplasma gondii phosphatidylinositol 3- and 4-kinase 0.0264 0.0147 0.1447
Echinococcus multilocularis cAMP specific 3',5' cyclic phosphodiesterase 0.0133 0.0063 0.0063
Mycobacterium ulcerans long-chain-fatty-acid-CoA ligase 0.0051 0.0011 0.0044
Loa Loa (eye worm) phosphatidylinositol 3 0.1343 0.0834 0.3204
Echinococcus granulosus Phosphatidylinositol 4 kinase type 2 beta 0.0264 0.0147 0.0147
Echinococcus granulosus hyperpolarization activated cyclic 0.0478 0.0283 0.0283
Loa Loa (eye worm) cyclic-nucleotide gated cation channel 0.0478 0.0283 0.1084
Mycobacterium tuberculosis Possible cytochrome P450 135A1 Cyp135A1 0.0067 0.0021 0.0113
Toxoplasma gondii 3'5'-cyclic nucleotide phosphodiesterase domain-containing protein 0.0133 0.0063 0.0592
Echinococcus granulosus potassium voltage gated channel subfamily H 0.0485 0.0287 0.0287
Mycobacterium ulcerans cytochrome p450 150 cyp150 0.0067 0.0021 0.0098
Schistosoma mansoni hypothetical protein 0.0179 0.0092 0.0943
Trypanosoma brucei Lanosterol 14-alpha demethylase 0.0067 0.0021 0.0157
Trypanosoma cruzi mitogen activated protein kinase 2, putative 0.1571 0.0979 0.2807
Mycobacterium ulcerans long-chain fatty-acid CoA ligase 0.0051 0.0011 0.0044
Schistosoma mansoni voltage-gated potassium channel 0.0467 0.0276 0.282
Trypanosoma cruzi cAMP phosphodiesterase A, putative 0.0133 0.0063 0.0166
Trichomonas vaginalis phosphatidylinositol kinase, putative 0.0264 0.0147 0.1447
Echinococcus multilocularis phosphatidylinositol 4 kinase alpha 0.0374 0.0217 0.0217
Onchocerca volvulus 0.0108 0.0048 0.1547
Mycobacterium ulcerans flavin-containing monoamine oxidase AofH 0.2987 0.1881 1
Trichomonas vaginalis fructose-bisphosphate aldolase, putative 0.0302 0.0171 0.1698
Giardia lamblia Dipeptidyl-peptidase I precursor 0.0085 0.0033 0.0278
Trichomonas vaginalis voltage and ligand gated potassium channel, putative 0.0478 0.0283 0.2846
Trypanosoma cruzi phosphatidylinositol 4-kinase alpha, putative 0.0374 0.0217 0.0609
Giardia lamblia Phosphoinositide-3-kinase, class 3 0.0402 0.0234 0.2349
Echinococcus granulosus potassium voltage gated channel subfamily C 0.0467 0.0276 0.0276
Brugia malayi Large-conductance calcium-activated potassium channel Slo-1 (KCNMA) alpha subunit. C. elegans slo-1 ortholog 0.0467 0.0276 0.1024
Trichomonas vaginalis PIKK family atypical protein kinase 0.0284 0.0159 0.1576
Toxoplasma gondii cytochrome p450 superfamily protein 0.0067 0.0021 0.0157
Echinococcus multilocularis 0.0409 0.0239 0.0239
Trypanosoma brucei inositol 1,4,5-trisphosphate receptor 0.0467 0.0276 0.2777
Brugia malayi Ryanodine Receptor TM 4-6 family protein 0.0467 0.0276 0.1024
Trichomonas vaginalis cAMP-specific 3,5-cyclic phosphodiesterase, putative 0.0479 0.0283 0.2852
Trichomonas vaginalis D-aminoacylase, putative 0.0108 0.0048 0.043
Plasmodium falciparum phosphodiesterase delta, putative 0.0133 0.0063 0.2834
Echinococcus multilocularis transient receptor potential cation channel 0.0467 0.0276 0.0276
Loa Loa (eye worm) hypothetical protein 0.0094 0.0039 0.0144
Onchocerca volvulus 0.0264 0.0147 0.5211
Leishmania major mitogen activated protein kinase 4, putative;with=GeneDB:LmxM19.1440 0.1571 0.0979 0.2677
Echinococcus granulosus TNFR CD27 30 40 95 cysteine rich region 0.0144 0.007 0.007
Loa Loa (eye worm) hypothetical protein 0.0723 0.0439 0.1686
Plasmodium vivax phosphatidylinositol 4-kinase, putative 0.0264 0.0147 0.6719
Echinococcus granulosus voltage dependent L type calcium channel subunit|voltage dependent calcium channel 0.0467 0.0276 0.0276
Echinococcus multilocularis voltage gated potassium channel 0.0485 0.0287 0.0287
Trichomonas vaginalis PIKK family atypical protein kinase 0.0734 0.0446 0.4524
Schistosoma mansoni ankyrin 23/unc44 0.0094 0.0039 0.0394
Leishmania major hypothetical protein, conserved 0.0133 0.0063 0.0158
Trichomonas vaginalis cAMP-specific phosphodiesterase, putative 0.0479 0.0283 0.2852
Loa Loa (eye worm) hypothetical protein 0.0055 0.0013 0.0048
Echinococcus multilocularis hyperpolarization activated cyclic 0.0478 0.0283 0.0283
Loa Loa (eye worm) calcium/calmodulin-stimulated cyclic nucleotide phosphodiesterase 0.0133 0.0063 0.024
Mycobacterium ulcerans cytochrome P450 143A3 Cyp143A3 0.0067 0.0021 0.0098
Trichomonas vaginalis cGMP-dependent 3,5-cyclic phosphodiesterase, putative 0.0479 0.0283 0.2852
Trypanosoma cruzi phosphatidylinositol 3-kinase, putative 0.0264 0.0147 0.0406
Trichomonas vaginalis PIKK family atypical protein kinase 0.126 0.0781 0.7968
Toxoplasma gondii target of rapamycin (TOR), putative 0.1275 0.079 0.8065
Echinococcus multilocularis epidermal growth factor receptor 0.132 0.0819 0.0819
Plasmodium falciparum protoporphyrinogen oxidase 0.021 0.0113 0.5127
Loa Loa (eye worm) hypothetical protein 0.0038 0.0003 0.0007
Echinococcus multilocularis 0.0264 0.0147 0.0147
Trichomonas vaginalis PIKK family atypical protein kinase 0.0833 0.0509 0.5171
Trypanosoma cruzi Phosphatidylinositol 3-kinase tor2 0.13 0.0806 0.2309
Echinococcus granulosus phosphatidylinositol 4 phosphate 3 kinase C2 0.0723 0.0439 0.0439
Mycobacterium tuberculosis Two component sensor histidine kinase DevS 0.0345 0.0199 0.1129
Loa Loa (eye worm) phosphatidylinositol 3 0.13 0.0806 0.3098
Plasmodium vivax phosphodiesterase gamma, putative 0.0133 0.0063 0.2834
Echinococcus granulosus mitogen activated protein kinase 3 0.1571 0.0979 0.0979
Loa Loa (eye worm) cytochrome P450 family protein 0.0234 0.0127 0.0486
Mycobacterium leprae Probable fructose bisphosphate aldolase Fba 0.0148 0.0073 0.329
Loa Loa (eye worm) hypothetical protein 0.0234 0.0128 0.0487
Treponema pallidum fructose-bisphosphate aldolase 0.0302 0.0171 0.5
Giardia lamblia Phosphoinositide-3-kinase, catalytic, alpha polypeptide 0.076 0.0463 0.4698
Echinococcus granulosus Ankyrin 0.0094 0.0039 0.0039
Trichomonas vaginalis PIKK family atypical protein kinase 0.075 0.0456 0.4631
Loa Loa (eye worm) hypothetical protein 0.0467 0.0276 0.1058
Loa Loa (eye worm) PDE1B protein 0.0133 0.0063 0.024
Echinococcus granulosus insulin receptor 0.0422 0.0247 0.0247
Chlamydia trachomatis protoporphyrinogen oxidase 0.021 0.0113 1
Trichomonas vaginalis rod cGMP-specific 3,5-cyclic phosphodiesterase, putative 0.0479 0.0283 0.2852
Brugia malayi amine oxidase, flavin-containing family protein 0.021 0.0113 0.0415
Echinococcus multilocularis potassium voltage gated channel subfamily D 0.0467 0.0276 0.0276
Brugia malayi Phosphatidylinositol 3- and 4-kinase family protein 0.13 0.0806 0.3
Echinococcus multilocularis Phosphatidylinositol 4 kinase type 2 beta 0.0264 0.0147 0.0147
Schistosoma mansoni transient receptor potential cation channel subfamily m member 0.0467 0.0276 0.282
Schistosoma mansoni voltage-gated potassium channel 0.0474 0.0281 0.2868
Plasmodium falciparum sentrin-specific protease 1 0.0043 0.0006 0.0146
Trichomonas vaginalis high-affinity cGMP-specific 3,5-cyclic phosphodiesterase, putative 0.0133 0.0063 0.0592
Schistosoma mansoni camp-specific 35-cyclic phosphodiesterase 0.0133 0.0063 0.0648
Mycobacterium ulcerans cytochrome P450 125A7 Cyp125A7 0.0067 0.0021 0.0098
Schistosoma mansoni voltage-dependent calcium channel 0.0467 0.0276 0.282
Schistosoma mansoni family C48 unassigned peptidase (C48 family) 0.0102 0.0044 0.0445
Schistosoma mansoni voltage-gated potassium channel 0.0467 0.0276 0.282
Trichomonas vaginalis conserved hypothetical protein 0.0133 0.0063 0.0592
Echinococcus multilocularis potassium voltage gated channel protein 0.0467 0.0276 0.0276
Trypanosoma cruzi hypothetical protein, conserved 0.5485 0.3472 1
Loa Loa (eye worm) hypothetical protein 0.0094 0.0039 0.0144
Schistosoma mansoni amine oxidase 0.021 0.0113 0.115
Loa Loa (eye worm) MH2 domain-containing protein 0.0123 0.0057 0.0216
Echinococcus granulosus short transient receptor potential channel 6 0.0467 0.0276 0.0276
Loa Loa (eye worm) hypothetical protein 0.0052 0.0011 0.004
Toxoplasma gondii preprocathepsin c precursor, putative 0.0217 0.0117 0.1142
Brugia malayi Death domain containing protein 0.0094 0.0039 0.014
Echinococcus granulosus tumor protein p63 0.0374 0.0217 0.0217
Toxoplasma gondii 3'5'-cyclic nucleotide phosphodiesterase domain-containing protein 0.0133 0.0063 0.0592
Trichomonas vaginalis PIKK family atypical protein kinase 0.13 0.0806 0.8227
Mycobacterium tuberculosis Probable conserved lipoprotein 0.0108 0.0048 0.0265
Schistosoma mansoni cyclic-nucleotide-gated cation channel 0.0478 0.0283 0.2889
Entamoeba histolytica FKBP-rapamycin associated protein (FRAP), putative 0.13 0.0806 1
Echinococcus granulosus voltage dependent calcium channel 0.0467 0.0276 0.0276
Trichomonas vaginalis fructose-bisphosphate aldolase, putative 0.0302 0.0171 0.1698
Loa Loa (eye worm) cytochrome P450 family protein 0.0087 0.0034 0.0128
Toxoplasma gondii CMGC kinase, MAPK family (ERK) MAPK-1 0.1571 0.0979 1
Schistosoma mansoni voltage-gated potassium channel 0.0549 0.0328 0.3351
Trichomonas vaginalis fructose-bisphosphate aldolase, putative 0.0302 0.0171 0.1698
Trypanosoma brucei hypothetical protein, conserved 0.0108 0.0048 0.043
Schistosoma mansoni phosphatidylinositol-45-bisphosphate 3-kinase catalytic subunit alpha PI3K 0.0374 0.0217 0.2216
Brugia malayi Ulp1 protease family, C-terminal catalytic domain containing protein 0.0102 0.0044 0.0158
Echinococcus multilocularis Basic leucine zipper (bZIP) transcription 0.0037 0.0002 0.0002
Echinococcus multilocularis phosphatidylinositol 3 and 4 kinase 0.1344 0.0834 0.0834
Echinococcus granulosus potassium voltage gated channel protein 0.0467 0.0276 0.0276
Brugia malayi Voltage-gated potassium channel, EAG (KCNH1)-related. C. elegans egl-2 ortholog 0.0485 0.0287 0.1067
Brugia malayi Calcitonin receptor-like protein seb-1 0.0052 0.0011 0.0039
Mycobacterium tuberculosis Probable hydrolase 0.0108 0.0048 0.0265
Trichomonas vaginalis PIKK family atypical protein kinase 0.1275 0.079 0.8065
Echinococcus granulosus transient receptor potential cation channel 0.0467 0.0276 0.0276
Trichomonas vaginalis PIKK family atypical protein kinase 0.0755 0.046 0.4664
Toxoplasma gondii 3'5'-cyclic nucleotide phosphodiesterase domain-containing protein 0.06 0.0361 0.3649
Schistosoma mansoni ataxia telangiectasia mutated (atm) 0.0742 0.0451 0.4612
Trichomonas vaginalis D-aminoacylase, putative 0.0108 0.0048 0.043
Schistosoma mansoni transcription factor LCR-F1 0.0037 0.0002 0.0024
Trichomonas vaginalis PIKK family atypical protein kinase 0.128 0.0794 0.8097
Trypanosoma cruzi Lanosterol 14-alpha demethylase 0.0067 0.0021 0.0044
Schistosoma mansoni tyrosine kinase 0.0709 0.043 0.4396
Trypanosoma cruzi phosphatidylinositol 4-kinase, putative 0.0264 0.0147 0.0406
Trichomonas vaginalis voltage and ligand gated potassium channel, putative 0.0478 0.0283 0.2846
Toxoplasma gondii 3'5'-cyclic nucleotide phosphodiesterase domain-containing protein 0.0133 0.0063 0.0592
Schistosoma mansoni tyrosine kinase 0.132 0.0819 0.837
Loa Loa (eye worm) hypothetical protein 0.0108 0.0048 0.0179
Brugia malayi AMP-binding enzyme family protein 0.0051 0.0011 0.0037
Echinococcus multilocularis lysine specific histone demethylase 1A 0.021 0.0113 0.0113
Entamoeba histolytica Ulp1 protease family, C-terminal catalytic domain containing protein 0.0043 0.0006 0.0044
Schistosoma mansoni transient receptor potential channel 0.0467 0.0276 0.282
Echinococcus multilocularis potassium voltage gated channel subfamily C 0.0467 0.0276 0.0276
Echinococcus granulosus cytochrome P450 2K1 0.0067 0.0021 0.0021
Trichomonas vaginalis phosphatidylinositol 3-kinase class, putative 0.0512 0.0305 0.3071
Mycobacterium tuberculosis Possible oxidoreductase 0.021 0.0113 0.0637
Mycobacterium ulcerans cytochrome P450 105Q4 Cyp105Q4 0.0067 0.0021 0.0098
Loa Loa (eye worm) hypothetical protein 0.0133 0.0063 0.024
Echinococcus granulosus mitogen activated protein kinase 0.1571 0.0979 0.0979
Schistosoma mansoni family S12 unassigned peptidase (S12 family) 0.0108 0.0048 0.0487
Echinococcus multilocularis two pore calcium channel protein 1 0.0467 0.0276 0.0276
Brugia malayi Voltage-gated potassium channel, KCNQ (Kv7-like) alpha-subunit. C. elegans kqt-1 ortholog 0.0467 0.0276 0.1024
Loa Loa (eye worm) hypothetical protein 0.0524 0.0313 0.1199
Plasmodium falciparum phosphodiesterase gamma, putative 0.0133 0.0063 0.2834
Brugia malayi AMP-binding enzyme family protein 0.0051 0.0011 0.0037
Trichomonas vaginalis conserved hypothetical protein 0.0345 0.0199 0.198
Echinococcus granulosus potassium voltage gated channel subfamily D 0.0467 0.0276 0.0276
Plasmodium vivax hypothetical protein, conserved 0.0108 0.0048 0.2097
Echinococcus multilocularis two pore calcium channel protein 2 0.0467 0.0276 0.0276
Echinococcus granulosus transient receptor potential cation channel 0.0467 0.0276 0.0276
Echinococcus multilocularis Niemann Pick C1 protein 0.0156 0.0078 0.0078
Schistosoma mansoni camp-specific cyclic nucleotide phosphodiesterase 0.0133 0.0063 0.0648
Brugia malayi Phosphatidylinositol 3- and 4-kinase family protein 0.0742 0.0451 0.1678
Trypanosoma brucei phosphatidylinositol 3-related kinase, putative 0.1258 0.078 0.7957
Trichomonas vaginalis high-affinity cGMP-specific 3,5-cyclic phosphodiesterase, putative 0.0479 0.0283 0.2852
Entamoeba histolytica phosphatidylinositol 3-kinase 1, putative 0.0846 0.0517 0.6404
Loa Loa (eye worm) hypothetical protein 0.021 0.0113 0.0429
Loa Loa (eye worm) hypothetical protein 0.0478 0.0283 0.1086
Trypanosoma brucei FAT domain/Rapamycin binding domain/Phosphatidylinositol 3- and 4-kinase, putative 0.0808 0.0493 0.501
Trichomonas vaginalis PIKK family atypical protein kinase 0.1275 0.079 0.8065
Loa Loa (eye worm) hypothetical protein 0.0467 0.0276 0.1058
Plasmodium falciparum phosphatidylinositol 4-kinase 0.0264 0.0147 0.6719
Plasmodium vivax hypothetical protein 0.0264 0.0147 0.6719
Leishmania major phosphatidylinositol 4-kinase alpha, putative 0.0374 0.0217 0.0581
Toxoplasma gondii 3'5'-cyclic nucleotide phosphodiesterase domain-containing protein 0.0133 0.0063 0.0592
Toxoplasma gondii 3'5'-cyclic nucleotide phosphodiesterase domain-containing protein 0.06 0.0361 0.3649
Plasmodium vivax cyclic nucleotide phosphodiesterase, putative 0.0133 0.0063 0.2834
Schistosoma mansoni high-affinity cgmp-specific 35-cyclic phosphodiesterase 0.0133 0.0063 0.0648
Plasmodium vivax phosphatidylinositol 4-kinase, putative 0.0264 0.0147 0.6719
Echinococcus granulosus geminin 0.0179 0.0092 0.0092
Echinococcus multilocularis cyclic nucleotide gated cation channel alpha 3 0.0478 0.0283 0.0283
Giardia lamblia Dipeptidyl-peptidase I precursor 0.0217 0.0117 0.1142
Echinococcus multilocularis conserved hypothetical protein 0.0467 0.0276 0.0276
Brugia malayi Phosphatidylinositol 3- and 4-kinase family protein 0.0264 0.0147 0.0542
Entamoeba histolytica acyl-CoA synthetase, putative 0.0051 0.0011 0.0107
Echinococcus granulosus sentrin specific protease 7 0.0192 0.0101 0.0101
Trichomonas vaginalis PIKK family atypical protein kinase 0.1255 0.0778 0.7935
Brugia malayi Voltage-gated calcium channel, P/Q-type, alpha subunit. C. elegans unc-2 ortholog 0.0467 0.0276 0.1024
Toxoplasma gondii transporter, cation channel family protein 0.0467 0.0276 0.2777
Mycobacterium tuberculosis Cytochrome P450 121 Cyp121 0.0067 0.0021 0.0113
Echinococcus granulosus death domain containing protein 0.0094 0.0039 0.0039
Schistosoma mansoni Lysine-specific histone demethylase 1 0.021 0.0113 0.115
Echinococcus multilocularis TRP (transient receptor potential) channel 0.0467 0.0276 0.0276
Plasmodium vivax hypothetical protein, conserved 0.021 0.0113 0.5127
Loa Loa (eye worm) hypothetical protein 0.0467 0.0276 0.1058
Schistosoma mansoni camp-specific 35-cyclic phosphodiesterase 0.0133 0.0063 0.0648
Echinococcus granulosus neuropeptide s receptor 0.0937 0.0576 0.0576
Echinococcus granulosus insulin growth factor 1 receptor beta 0.0422 0.0247 0.0247
Mycobacterium leprae Conserved hypothetical protein 0.0067 0.0021 0.0543
Loa Loa (eye worm) hypothetical protein 0.0038 0.0003 0.0007
Mycobacterium tuberculosis Conserved hypothetical protein 0.021 0.0113 0.0637
Trichomonas vaginalis PIKK family atypical protein kinase 0.13 0.0806 0.8227
Loa Loa (eye worm) hypothetical protein 0.0108 0.0048 0.0179
Trichomonas vaginalis fructose-bisphosphate aldolase, putative 0.0302 0.0171 0.1698
Loa Loa (eye worm) hypothetical protein 0.0467 0.0276 0.1058
Brugia malayi 3'5'-cyclic nucleotide phosphodiesterase family protein 0.0133 0.0063 0.0233
Loa Loa (eye worm) hypothetical protein 0.0108 0.0048 0.0179
Echinococcus granulosus calcium:calmodulin dependent 3'5' cyclic 0.0133 0.0063 0.0063
Brugia malayi Probable 3',5'-cyclic phosphodiesterase T04D3.3, putative 0.0133 0.0063 0.0233
Schistosoma mansoni camp/cgmp cyclic nucleotide phosphodiesterase 0.0479 0.0283 0.2895
Loa Loa (eye worm) hypothetical protein 0.0467 0.0276 0.1058
Loa Loa (eye worm) Ulp1 protease 0.0102 0.0044 0.0164
Trichomonas vaginalis cyclic nucleotide phosphodiesterase, putative 0.0479 0.0283 0.2852
Schistosoma mansoni survival motor neuron protein 0.0048 0.0009 0.0092
Echinococcus multilocularis calcium activated potassium channel 0.0481 0.0285 0.0285
Trichomonas vaginalis conserved hypothetical protein 0.0345 0.0199 0.198
Schistosoma mansoni hyperpolarization activated cyclic nucleotide-gated potassium channel 0.0478 0.0283 0.2889
Schistosoma mansoni P2X receptor subunit 0.0076 0.0027 0.0277
Echinococcus granulosus transient receptor potential cation channel 0.0467 0.0276 0.0276
Brugia malayi Cyclic-nucleotide gated cation channel 0.0478 0.0283 0.1049
Trichomonas vaginalis phosphatidylinositol 4-kinase, putative 0.0374 0.0217 0.2169
Plasmodium vivax hypothetical protein, conserved 0.021 0.0113 0.5127
Trichomonas vaginalis CMGC family protein kinase 0.1571 0.0979 1
Schistosoma mansoni tyrosine kinase 0.0702 0.0426 0.4347
Brugia malayi phosphatidylinositol 4-kinase, catalytic, alpha polypeptide 0.0374 0.0217 0.0804
Echinococcus multilocularis phosphatidylinositol 4 phosphate 3 kinase C2 0.0723 0.0439 0.0439
Trypanosoma brucei phosphatidylinositol 3-kinase tor, putative 0.0303 0.0172 0.1706
Schistosoma mansoni fkbp-rapamycin associated protein 0.0711 0.0431 0.4407
Schistosoma mansoni calcium channel voltage-dependent p/q type alpha 1a-related 0.0467 0.0276 0.282
Entamoeba histolytica phosphatidylinositol 3-kinase, putative 0.0512 0.0305 0.3761
Toxoplasma gondii phosphatidylinositol 3- and 4-kinase 0.0264 0.0147 0.1447
Loa Loa (eye worm) cytochrome P450 0.0067 0.0021 0.0077
Giardia lamblia Kinase, CMGC MAPK 0.1571 0.0979 1
Trichomonas vaginalis cyclic nucleotide phosphodiesterase, putative 0.0133 0.0063 0.0592
Giardia lamblia CAMP-specific 3,5-cyclic phosphodiesterase 4B 0.0133 0.0063 0.0592
Trichomonas vaginalis cyclic nucleotide phosphodiesterase, putative 0.0479 0.0283 0.2852
Loa Loa (eye worm) cyclic-nucleotide gated cation channel 0.0478 0.0283 0.1084
Trichomonas vaginalis cAMP/cGMP cyclic nucleotide phosphodiesterase, putative 0.0479 0.0283 0.2852
Echinococcus multilocularis mitogen activated protein kinase 0.1571 0.0979 0.0979
Trypanosoma cruzi mitogen-activated protein kinase 11, putative 0.1571 0.0979 0.2807
Trichomonas vaginalis cone cGMP-specific 3,5-cyclic phosphodiesterase, putative 0.0479 0.0283 0.2852
Echinococcus granulosus netrin receptor unc 5 0.0094 0.0039 0.0039
Echinococcus multilocularis p2X purinoceptor 4 0.0076 0.0027 0.0027
Loa Loa (eye worm) hypothetical protein 0.0051 0.0011 0.0038
Trichomonas vaginalis PIKK family atypical protein kinase 0.0447 0.0263 0.2646
Schistosoma mansoni hypothetical protein 0.0045 0.0007 0.0075
Toxoplasma gondii 3'5'-cyclic nucleotide phosphodiesterase domain-containing protein 0.0133 0.0063 0.0592
Echinococcus granulosus voltage gated sodium channel Nav1 alpha subunit 0.3467 0.2186 0.2186
Echinococcus multilocularis sterol regulatory element binding protein 0.0047 0.0008 0.0008
Loa Loa (eye worm) hypothetical protein 0.0038 0.0003 0.0007
Plasmodium vivax dipeptidyl aminopeptidase 1, putative 0.0217 0.0117 0.5332
Loa Loa (eye worm) TK/INSR protein kinase 0.0422 0.0247 0.0947
Echinococcus granulosus expressed conserved protein 0.0149 0.0074 0.0074
Trypanosoma cruzi phosphatidylinositol 3-kinase vps34-like 0.0512 0.0305 0.0862
Trichomonas vaginalis cGMP-dependent 3,5-cyclic phosphodiesterase, putative 0.0133 0.0063 0.0592
Trichomonas vaginalis phopsphatidylinositol 3-kinase, drosophila, putative 0.111 0.0685 0.6983
Entamoeba histolytica hypothetical protein 0.0264 0.0147 0.1796
Plasmodium vivax sentrin-specific protease 2, putative 0.0043 0.0006 0.0146
Trypanosoma cruzi target of rapamycin kinase 3 0.128 0.0794 0.2273
Mycobacterium ulcerans beta-lactamase 0.0108 0.0048 0.0239
Echinococcus granulosus Phosphatidylinositol 4 kinase type 2 beta 0.0264 0.0147 0.0147
Echinococcus granulosus beta LACTamase domain containing family member 0.0108 0.0048 0.0048
Echinococcus multilocularis transient receptor potential cation channel 0.0467 0.0276 0.0276
Trichomonas vaginalis PIKK family atypical protein kinase 0.13 0.0806 0.8227
Echinococcus multilocularis transient receptor potential cation channel 0.0467 0.0276 0.0276
Leishmania major phosphatidylinositol 3-related kinase, putative 0.1258 0.078 0.213
Entamoeba histolytica Ulp1 protease family, C-terminal catalytic domain containing protein 0.0043 0.0006 0.0044
Loa Loa (eye worm) phosphatidylinositol 3 0.0264 0.0147 0.056
Schistosoma mansoni voltage-gated potassium channel KCNQ 0.0467 0.0276 0.282
Mycobacterium ulcerans cytochrome P450 150A6 Cyp150A6 0.0067 0.0021 0.0098
Brugia malayi Phosphatidylinositol 3- and 4-kinase family protein 0.111 0.0685 0.2549
Mycobacterium tuberculosis Conserved protein 0.0108 0.0048 0.0265
Toxoplasma gondii 3'5'-cyclic nucleotide phosphodiesterase domain-containing protein 0.0133 0.0063 0.0592
Loa Loa (eye worm) pigment dispersing factor receptor c 0.0052 0.0011 0.004
Trichomonas vaginalis PIKK family atypical protein kinase 0.1255 0.0778 0.7935
Loa Loa (eye worm) hypothetical protein 0.0467 0.0276 0.1058
Echinococcus granulosus high affinity cAMP specific 3'5' cyclic 0.0133 0.0063 0.0063
Echinococcus granulosus epidermal growth factor receptor 0.0709 0.043 0.043
Giardia lamblia Dipeptidyl-peptidase I precursor 0.0085 0.0033 0.0278
Trichomonas vaginalis high-affinity cGMP-specific 3,5-cyclic phosphodiesterase, putative 0.0479 0.0283 0.2852
Trypanosoma cruzi phosphatidylinositol 3-related kinase, putative 0.1344 0.0834 0.239
Loa Loa (eye worm) abnormal chemotaxis protein 14 0.0047 0.0008 0.0028
Trichomonas vaginalis voltage and ligand gated potassium channel, putative 0.0074 0.0026 0.0205
Trichomonas vaginalis PIKK family atypical protein kinase 0.1235 0.0765 0.7806
Loa Loa (eye worm) phosphatidylinositol 3 0.0264 0.0147 0.056
Loa Loa (eye worm) CMGC/MAPK/ERK1 protein kinase 0.1571 0.0979 0.3761
Mycobacterium tuberculosis Probable esterase/lipase LipP 0.0108 0.0048 0.0265
Plasmodium falciparum cGMP-specific phosphodiesterase 0.0133 0.0063 0.2834
Mycobacterium ulcerans acyl-CoA synthetase 0.0051 0.0011 0.0044
Brugia malayi Phosphatidylinositol 3- and 4-kinase family protein 0.1344 0.0834 0.3104
Entamoeba histolytica phosphatidylinositol 3-kinase, putative 0.111 0.0685 0.8494
Trichomonas vaginalis PIKK family atypical protein kinase 0.0775 0.0472 0.4794
Echinococcus multilocularis protein patched 0.0047 0.0008 0.0008
Trichomonas vaginalis cAMP-specific phosphodiesterase, putative 0.0479 0.0283 0.2852
Loa Loa (eye worm) hypothetical protein 0.0479 0.0283 0.1086
Schistosoma mansoni cyclic-nucleotide-gated cation channel 0.0478 0.0283 0.2889
Schistosoma mansoni ryanodine receptor related 0.0467 0.0276 0.282
Loa Loa (eye worm) hypothetical protein 0.0047 0.0008 0.0028
Toxoplasma gondii 3'5'-cyclic nucleotide phosphodiesterase domain-containing protein 0.0133 0.0063 0.0592
Toxoplasma gondii hypothetical protein 0.0345 0.0199 0.198
Trichomonas vaginalis Clan CE, family C48, Ulp1-like cysteine peptidase 0.0102 0.0044 0.0387
Trichomonas vaginalis PIKK family atypical protein kinase 0.1255 0.0778 0.7935
Echinococcus multilocularis geminin 0.0179 0.0092 0.0092
Mycobacterium ulcerans epoxide hydrolase EphA 0.016 0.0081 0.0414
Toxoplasma gondii transporter, cation channel family protein 0.0467 0.0276 0.2777
Schistosoma mansoni P2X receptor subunit 0.0076 0.0027 0.0277
Entamoeba histolytica hypothetical protein 0.0264 0.0147 0.1796
Trypanosoma brucei 3', 5'-cyclic nucleotide phosphodiesterase, putative 0.0133 0.0063 0.0592
Toxoplasma gondii 3'5'-cyclic nucleotide phosphodiesterase domain-containing protein 0.0133 0.0063 0.0592
Trichomonas vaginalis phosphatidylinositol kinase, putative 0.0512 0.0305 0.3071
Trichomonas vaginalis fructose-bisphosphate aldolase, putative 0.0302 0.0171 0.1698
Schistosoma mansoni high-affinity cgmp-specific 35-cyclic phosphodiesterase 0.0133 0.0063 0.0648
Plasmodium vivax dipeptidyl aminopeptidase 2, putative 0.0217 0.0117 0.5332
Echinococcus granulosus short transient receptor potential channel 6 0.0467 0.0276 0.0276
Loa Loa (eye worm) hypothetical protein 0.0057 0.0015 0.0054
Trichomonas vaginalis phosphatidylinositol kinase, putative 0.0374 0.0217 0.2169
Trypanosoma cruzi hypothetical protein, conserved 0.0133 0.0063 0.0166
Trypanosoma cruzi hypothetical protein, conserved 0.0108 0.0048 0.0121
Trypanosoma cruzi cAMP specific phosphodiesterase, putative 0.0479 0.0283 0.0801
Trichomonas vaginalis PIKK family atypical protein kinase 0.1275 0.079 0.8065
Entamoeba histolytica acyl-CoA synthetase, putative 0.0051 0.0011 0.0107
Echinococcus multilocularis hyperpolarization activated cyclic 0.0478 0.0283 0.0283
Mycobacterium tuberculosis Cytochrome P450 51 Cyp51 (CYPL1) (P450-L1A1) (sterol 14-alpha demethylase) (lanosterol 14-alpha demethylase) (P450-14DM) 0.0067 0.0021 0.0113
Echinococcus granulosus epidermal growth factor receptor 0.132 0.0819 0.0819
Trichomonas vaginalis cAMP and cAMP-inhibited cGMP 3,5-cyclic phosphodiesterase, putative 0.0133 0.0063 0.0592
Echinococcus granulosus Niemann Pick C1 protein 0.0109 0.0048 0.0048
Trypanosoma cruzi phosphatidylinositol 4-kinase, putative 0.0264 0.0147 0.0406
Brugia malayi Cytochrome P450 family protein 0.0067 0.0021 0.0075
Echinococcus granulosus voltage dependent calcium channel type d subunit|voltage dependent calcium channel alpha 1 0.0467 0.0276 0.0276
Schistosoma mansoni 60S ribosomal protein L21 0.0474 0.0281 0.2868
Trypanosoma cruzi UDP-galactopyranose mutase 0.021 0.0113 0.0308
Mycobacterium leprae Probable lipase LipE 0.0108 0.0048 0.1959
Mycobacterium ulcerans fusion of enoyl-CoA hydratase, EchA21 and lipase, LipE 0.0108 0.0048 0.0239
Plasmodium falciparum dipeptidyl aminopeptidase 1 0.0217 0.0117 0.5332
Echinococcus multilocularis sentrin specific protease 1 0.0043 0.0006 0.0006
Loa Loa (eye worm) calcium channel 0.0467 0.0276 0.1058
Toxoplasma gondii cathepsin CPC2 0.0085 0.0033 0.0278
Echinococcus granulosus potassium voltage gated channel protein 0.0467 0.0276 0.0276
Toxoplasma gondii 3'5'-cyclic nucleotide phosphodiesterase domain-containing protein 0.0133 0.0063 0.0592
Loa Loa (eye worm) hypothetical protein 0.0108 0.0048 0.0179
Trypanosoma brucei phosphatidylinositol kinase related protein, putative 0.0742 0.0451 0.4579
Echinococcus granulosus lysine specific histone demethylase 1A 0.021 0.0113 0.0113
Loa Loa (eye worm) voltage-gated potassium channel 0.0467 0.0276 0.1058
Echinococcus granulosus ankyrin repeat and death domain containing protein 0.0094 0.0039 0.0039
Echinococcus multilocularis insulin growth factor 1 receptor beta 0.0422 0.0247 0.0247
Trichomonas vaginalis conserved hypothetical protein 0.0345 0.0199 0.198
Trichomonas vaginalis Clan CA, family C1, cathepsin B-like cysteine peptidase 0.0137 0.0066 0.0614
Trypanosoma cruzi inositol 1,4,5-trisphosphate receptor, putative 0.0467 0.0276 0.078
Schistosoma mansoni voltage-gated potassium channel 0.0467 0.0276 0.282
Trichomonas vaginalis cGMP-specific 3,5-cyclic phosphodiesterase, putative 0.0479 0.0283 0.2852
Loa Loa (eye worm) hypothetical protein 0.021 0.0113 0.0429
Trichomonas vaginalis PIKK family atypical protein kinase 0.1255 0.0778 0.7936
Echinococcus granulosus voltage dependent calcium channel type d subunit|voltage dependent calcium channel|voltage dependent L type calcium channel subu 0.0467 0.0276 0.0276
Brugia malayi Hypothetical 52.5 kDa protein ZK945.1 in chromosome II, putative 0.0108 0.0048 0.0174
Mycobacterium ulcerans fatty-acid-CoA ligase 0.0051 0.0011 0.0044
Echinococcus multilocularis ankyrin repeat and death domain containing protein 0.0094 0.0039 0.0039
Echinococcus granulosus p2X purinoceptor 4 0.0076 0.0027 0.0027
Echinococcus multilocularis Phosphatidylinositol 4 kinase type 2 beta 0.0264 0.0147 0.0147
Brugia malayi voltage-dependent calcium channel 0.0467 0.0276 0.1024
Echinococcus multilocularis potassium voltage gated channel subfamily KQT 0.0467 0.0276 0.0276
Schistosoma mansoni ataxia telangiectasia mutated (atm)-related 0.13 0.0806 0.8238
Brugia malayi Voltage-gated potassium channel, Shaker-family (KCNA, Kv1-like) alpha-subunit 0.0467 0.0276 0.1024
Brugia malayi Probable 3',5'-cyclic phosphodiesterase R153.1, putative 0.0133 0.0063 0.0233
Toxoplasma gondii cathepsin CPC1 0.0217 0.0117 0.1142
Echinococcus granulosus phosphatidylinositol 45 bisphosphate 3 kinase 0.1481 0.0922 0.0922
Trypanosoma cruzi Lanosterol 14-alpha demethylase 0.0067 0.0021 0.0044
Echinococcus granulosus potassium voltage gated channel subfamily D 0.0467 0.0276 0.0276
Loa Loa (eye worm) phosphatidylinositol 3 0.1258 0.078 0.2997
Brugia malayi hypothetical protein 0.0037 0.0002 0.0005
Toxoplasma gondii 3'5'-cyclic nucleotide phosphodiesterase domain-containing protein 0.0133 0.0063 0.0592
Trypanosoma brucei hypothetical protein, conserved 0.0133 0.0063 0.0592
Echinococcus granulosus shaker cognate 0.0467 0.0276 0.0276
Mycobacterium leprae conserved hypothetical protein 0.0264 0.0147 0.7236
Trichomonas vaginalis high-affinity cGMP-specific 3,5-cyclic phosphodiesterase, putative 0.0133 0.0063 0.0592
Echinococcus multilocularis 0.021 0.0113 0.0113
Schistosoma mansoni transient receptor potential cation channel subfamily m member 0.0467 0.0276 0.282
Echinococcus multilocularis p2X purinoceptor 4 0.0076 0.0027 0.0027
Loa Loa (eye worm) hypothetical protein 0.021 0.0113 0.0429
Loa Loa (eye worm) hypothetical protein 0.0467 0.0276 0.1058
Giardia lamblia Hypothetical protein 0.0133 0.0063 0.0592
Echinococcus multilocularis netrin receptor unc 5 0.0094 0.0039 0.0039
Echinococcus multilocularis potassium voltage gated channel protein 0.0467 0.0276 0.0276
Leishmania major cytochrome p450-like protein 0.0067 0.0021 0.0042
Trypanosoma brucei 3', 5'-cyclic nucleotide phosphodiesterase, putative 0.0133 0.0063 0.0592
Loa Loa (eye worm) hypothetical protein 0.0108 0.0048 0.0179
Brugia malayi hypothetical protein 0.0467 0.0276 0.1024
Leishmania major hypothetical protein, unknown function 0.0264 0.0147 0.0387
Brugia malayi CHE-14 protein 0.0047 0.0008 0.0027
Mycobacterium tuberculosis Probable fructose-bisphosphate aldolase Fba 0.0148 0.0073 0.0408
Brugia malayi Voltage-gated calcium channel, L-type, alpha subunit. C. elegans egl-19 ortholog 0.0467 0.0276 0.1024
Echinococcus granulosus Niemann Pick C1 protein 0.0156 0.0078 0.0078
Trypanosoma cruzi phosphatidylinositol 3-kinase, putative 0.0711 0.0431 0.1228
Plasmodium vivax 3',5'-cyclic nucleotide phosphodiesterase, putative 0.0133 0.0063 0.2834
Trichomonas vaginalis phosphatidylinositol 3-kinase catalytic subunit alpha, beta, delta, putative 0.0512 0.0305 0.3071
Echinococcus granulosus cAMP and cAMP inhibited cGMP 3'5' cyclic 0.425 0.2685 0.2685
Trypanosoma cruzi cAMP specific phosphodiesterase, putative 0.0133 0.0063 0.0166
Trypanosoma cruzi phosphatidylinositol kinase related protein, putative 0.0742 0.0451 0.1285
Echinococcus multilocularis FKBP12 rapamycin complex associated protein 0.13 0.0806 0.0806
Toxoplasma gondii transporter, cation channel family protein 0.0467 0.0276 0.2777
Trichomonas vaginalis PIKK family atypical protein kinase 0.1235 0.0765 0.7806
Mycobacterium tuberculosis Probable cytochrome P450 140 Cyp140 0.0067 0.0021 0.0113
Echinococcus granulosus high affinity cgmp specific 3' 5' cyclic 0.0133 0.0063 0.0063
Mycobacterium tuberculosis Probable cytochrome P450 124 Cyp124 0.0067 0.0021 0.0113
Echinococcus multilocularis survival motor neuron protein 1 0.0234 0.0128 0.0128
Loa Loa (eye worm) hypothetical protein 0.0485 0.0287 0.1101
Schistosoma mansoni voltage-gated potassium channel 0.0485 0.0287 0.2936
Trichomonas vaginalis PIKK family atypical protein kinase 0.1275 0.079 0.8065
Trichomonas vaginalis cyclic nucleotide phosphodiesterase, putative 0.0133 0.0063 0.0592
Loa Loa (eye worm) hypothetical protein 0.021 0.0113 0.0429
Mycobacterium ulcerans cytochrome P450 136A2 Cyp136A2 0.0067 0.0021 0.0098
Entamoeba histolytica phosphatidylinositol3-kinaseTor2, putative 0.13 0.0806 1
Schistosoma mansoni phosphatidylinositol-45-bisphosphate 3-kinase catalytic subunit alpha PI3K 0.0512 0.0305 0.3113
Schistosoma mansoni hypothetical protein 0.0035 0.0001 0.0011
Brugia malayi Protein kinase domain containing protein 0.0422 0.0247 0.0917
Echinococcus granulosus potassium voltage gated channel subfamily A 0.0467 0.0276 0.0276
Brugia malayi Cytochrome P450 family protein 0.0087 0.0034 0.0124
Toxoplasma gondii phosphatidylinositol 3- and 4-kinase 0.0264 0.0147 0.1447
Plasmodium falciparum conserved Plasmodium protein, unknown function 0.021 0.0113 0.5127
Schistosoma mansoni tumor necrosis factor receptor related 0.0144 0.007 0.0717
Trichomonas vaginalis PIKK family atypical protein kinase 0.0711 0.0431 0.4373
Schistosoma mansoni voltage-gated potassium channel 0.0467 0.0276 0.282
Leishmania major cytochrome p450-like protein 0.0087 0.0034 0.0078
Toxoplasma gondii phosphatidylinositol 3- and 4-kinase 0.0374 0.0217 0.2169
Loa Loa (eye worm) hypothetical protein 0.0038 0.0003 0.0007
Trypanosoma cruzi cyclic nucleotide phosphodiesterase 0.0133 0.0063 0.0166
Schistosoma mansoni voltage-gated cation channel 0.0467 0.0276 0.282
Trichomonas vaginalis high-affinity cGMP-specific 3,5-cyclic phosphodiesterase, putative 0.0479 0.0283 0.2852
Trypanosoma cruzi phosphatidylinositol 3-kinase 2, putative 0.111 0.0685 0.196
Loa Loa (eye worm) phosphatidylinositol 4-kinase type 3 alpha isoform 1 0.0374 0.0217 0.083
Echinococcus multilocularis p2X purinoceptor 4 0.0076 0.0027 0.0027
Trichomonas vaginalis Clan CE, family C48, Ulp1-like cysteine peptidase 0.0102 0.0044 0.0387
Loa Loa (eye worm) voltage-dependent calcium channel 0.0467 0.0276 0.1058
Entamoeba histolytica Niemann-Pick C1 protein, putative 0.0109 0.0048 0.0568
Leishmania major hypothetical protein, conserved 0.0108 0.0048 0.0115
Schistosoma mansoni hypothetical protein 0.0037 0.0002 0.0024
Echinococcus multilocularis dual 3',5' cyclic AMP and GMP phosphodiesterase 0.0479 0.0283 0.0283
Loa Loa (eye worm) hypothetical protein 0.0467 0.0276 0.1058
Echinococcus granulosus potassium voltage gated channel subfamily D 0.0467 0.0276 0.0276
Echinococcus granulosus potassium voltage gated channel subfamily H 0.0541 0.0323 0.0323
Brugia malayi Protein kinase domain containing protein 0.0108 0.0048 0.0174
Schistosoma mansoni voltage-gated potassium channel 0.0467 0.0276 0.282
Echinococcus multilocularis tumor protein p63 0.0374 0.0217 0.0217
Schistosoma mansoni transient receptor potential channel 0.0467 0.0276 0.282
Schistosoma mansoni patched 1 0.0047 0.0008 0.0086
Loa Loa (eye worm) hypothetical protein 0.0478 0.0283 0.1084
Echinococcus multilocularis voltage gated potassium channel 0.0467 0.0276 0.0276
Schistosoma mansoni hypothetical protein 0.0045 0.0007 0.0075
Echinococcus granulosus hypothetical protein 0.0467 0.0276 0.0276
Echinococcus granulosus cAMP specific 3'5' cyclic phosphodiesterase 0.0133 0.0063 0.0063
Brugia malayi cation channel family protein 0.0467 0.0276 0.1024
Echinococcus granulosus transient receptor potential cation channel 0.0467 0.0276 0.0276
Leishmania major hypothetical protein, conserved 0.5749 0.364 1
Mycobacterium ulcerans dehydrogenase 0.021 0.0113 0.0585
Echinococcus multilocularis potassium voltage gated channel subfamily A 0.0467 0.0276 0.0276
Brugia malayi Phosphatidylinositol 3- and 4-kinase family protein 0.0711 0.0431 0.1603
Loa Loa (eye worm) hypothetical protein 0.0467 0.0276 0.1058
Brugia malayi hypothetical protein 0.0234 0.0128 0.0472
Echinococcus multilocularis serine:threonine protein kinase SMG1 0.0711 0.0431 0.0431
Trypanosoma cruzi Phosphatidylinositol 3-kinase tor1 0.13 0.0806 0.2309
Trichomonas vaginalis fructose-bisphosphate aldolase, putative 0.0302 0.0171 0.1698
Entamoeba histolytica Ulp1 protease family, C-terminal catalytic domain containing protein 0.0102 0.0044 0.0513
Mycobacterium leprae PROBABLE PROTOPORPHYRINOGEN OXIDASE HEMY (PROTOPORPHYRINOGEN-IX OXIDASE) (PROTOPORPHYRINOGENASE) (PPO) 0.021 0.0113 0.5418
Brugia malayi Voltage-gated potassium channel, HERG (KCNH2)-related. C. elegans unc-103 ortholog 0.0541 0.0323 0.12
Schistosoma mansoni serine/threonine protein kinase 0.1571 0.0979 1
Plasmodium falciparum lysine-specific histone demethylase 1, putative 0.021 0.0113 0.5127
Echinococcus granulosus phosphatidylinositol 4 kinase beta 0.0264 0.0147 0.0147
Trichomonas vaginalis calcium/calmodulin-dependent 3,5-cyclic nucleotide phosphodiesterase, putative 0.0479 0.0283 0.2852
Trypanosoma brucei cytochrome P450, putative 0.0087 0.0034 0.0291
Loa Loa (eye worm) ion channel NompC 0.0467 0.0276 0.1058
Trypanosoma brucei cAMP phosphodiesterase A, putative 0.0133 0.0063 0.0592
Echinococcus granulosus PIK kinase FAT and Armadillo domain containing protein 0.0524 0.0313 0.0313
Echinococcus granulosus phosphatidylinositol 4 kinase alpha 0.0374 0.0217 0.0217
Mycobacterium ulcerans cytochrome P450 188A3 Cyp188A3 0.0067 0.0021 0.0098
Mycobacterium ulcerans cytochrome P450 143A4 Cyp143A4 0.0067 0.0021 0.0098
Echinococcus multilocularis potassium voltage gated channel protein 0.0467 0.0276 0.0276
Echinococcus granulosus potassium voltage gated channel protein 0.0467 0.0276 0.0276
Entamoeba histolytica hypothetical protein 0.0742 0.0451 0.5586
Onchocerca volvulus 0.0264 0.0147 0.5211
Mycobacterium ulcerans flavin-containing monoamine oxidase AofH 0.2987 0.1881 1
Echinococcus multilocularis potassium voltage gated channel subfamily H 0.0541 0.0323 0.0323
Entamoeba histolytica phosphatidylinositol 3-kinase 3, putative 0.0264 0.0147 0.1796
Leishmania major 4-coumarate:coa ligase-like protein 0.0051 0.0011 0.0014
Trichomonas vaginalis PIKK family atypical protein kinase 0.1258 0.078 0.7957
Plasmodium falciparum 3',5'-cyclic nucleotide phosphodiesterase, putative 0.0133 0.0063 0.2834
Echinococcus granulosus two pore calcium channel protein 2 0.0467 0.0276 0.0276
Mycobacterium ulcerans putative regulatory protein 0.0345 0.0199 0.1042
Schistosoma mansoni niemann-pick C1 (NPC1) 0.0111 0.0049 0.0501
Mycobacterium tuberculosis Possible penicillin-binding protein 0.0693 0.042 0.2397
Brugia malayi Voltage-gated potassium channel, Shab-family (KCNB, Kv2-like) alpha-subunit. C. elegans exp-2 ortholog 0.0467 0.0276 0.1024
Schistosoma mansoni vesicular amine transporter 0.0467 0.0276 0.282
Trichomonas vaginalis PIKK family atypical protein kinase 0.126 0.0781 0.7968
Schistosoma mansoni transient receptor potential cation channel subfamily m member 0.0467 0.0276 0.282
Echinococcus granulosus potassium voltage gated channel protein 0.0467 0.0276 0.0276
Echinococcus granulosus survival motor neuron protein 1 0.0234 0.0128 0.0128
Loa Loa (eye worm) immunoglobulin I-set domain-containing protein 0.0094 0.0039 0.0144
Trypanosoma brucei mitogen activated protein kinase 4, putative 0.1571 0.0979 1
Trichomonas vaginalis rod cGMP-specific 3,5-cyclic phosphodiesterase, putative 0.0479 0.0283 0.2852
Echinococcus multilocularis expressed conserved protein 0.0149 0.0074 0.0074
Echinococcus multilocularis short transient receptor potential channel 6 0.0467 0.0276 0.0276
Trichomonas vaginalis cGMP-dependent 3,5-cyclic phosphodiesterase, putative 0.0479 0.0283 0.2852
Mycobacterium ulcerans esterase/lipase LipP 0.0108 0.0048 0.0239
Mycobacterium ulcerans cytochrome P450 124A1, Cyp124A1 0.0067 0.0021 0.0098
Loa Loa (eye worm) voltage-gated potassium channel 0.0467 0.0276 0.1058
Loa Loa (eye worm) hypothetical protein 0.0043 0.0006 0.0019
Mycobacterium tuberculosis Possible cytochrome P450 126 Cyp126 0.0067 0.0021 0.0113
Mycobacterium tuberculosis Possible cytochrome P450 135B1 Cyp135B1 0.0067 0.0021 0.0113
Schistosoma mansoni high voltage-activated calcium channel Cav1 0.0467 0.0276 0.282
Mycobacterium tuberculosis Probable cytochrome P450 128 Cyp128 0.0067 0.0021 0.0113
Trichomonas vaginalis conserved hypothetical protein 0.0524 0.0313 0.3153
Echinococcus multilocularis sodium leak channel non selective protein 0.0467 0.0276 0.0276
Trichomonas vaginalis phosphatidylinositol 3-kinase catalytic subunit alpha, beta, delta, putative 0.0898 0.0551 0.56
Trypanosoma cruzi hypothetical protein, conserved 0.0133 0.0063 0.0166
Loa Loa (eye worm) hypothetical protein 0.0788 0.0481 0.1845
Schistosoma mansoni tyrosine kinase 0.0709 0.043 0.4396
Mycobacterium leprae conserved hypothetical protein 0.0108 0.0048 0.1959
Entamoeba histolytica fructose-1,6-bisphosphate aldolase, putative 0.0302 0.0171 0.2099
Trichomonas vaginalis conserved hypothetical protein 0.0133 0.0063 0.0592
Echinococcus multilocularis sodium channel protein 0.3467 0.2186 0.2186
Brugia malayi Immunoglobulin I-set domain containing protein 0.0094 0.0039 0.014
Mycobacterium ulcerans oxidoreductase 0.021 0.0113 0.0585
Loa Loa (eye worm) phosphatidylinositol 3 0.0248 0.0137 0.0522
Echinococcus granulosus transient receptor potential cation channel 0.0467 0.0276 0.0276
Entamoeba histolytica Ulp1 protease family, C-terminal catalytic domain containing protein 0.0043 0.0006 0.0044

Activities

Activity type Activity value Assay description Source Reference
Activity (functional) = 5 % Cell cycle arrest in human MCF7 cells assessed as accumulation at sub-G1 phase at IC50 concentration after 24 hrs using propidium iodide staining by flow cytometry ChEMBL. 21109433
IC50 (functional) = 9.4 ug ml-1 Antiproliferative activity against human MCF7 cells after 48 hrs by MTT assay ChEMBL. 21109433

Phenotypes

Whole-cell/tissue/organism interactions

Species name Source Reference Is orphan
Homo sapiens ChEMBL23 21109433

Many chemical entities in TDR Targets come from high-throughput screenings with whole cells or tissue samples, and not all assayed compounds have been tested against a single a single target protein, probably because they get ruled out during screening process. Even if these compounds may have not been of interest in the original screening, they may come as interesting leads for other screening assays. Furthermore, we may be able to propose drug-target associations using chemical similarities and network patterns.

Annotated phenotypes:

We have no manually annotated phenotypes for this drug. What does this mean? / Care to help?
In TDR Targets, information about phenotypes that are caused by drugs, or by genetic manipulation of cells (e.g. gene knockouts or knockdowns) is manually curated from the literature. These descriptions help to describe the potential of the target for drug development. If no information is available for this gene or if the information is incomplete, this may mean that i) the papers containing this information either appeared after the curation effort for this organism was carried out or they were inadvertently missed by curators; or that ii) the curation effort for this organism has not yet started.
 
In any case, if you have information about papers containing relevant validation data for this target, please log in using your TDR Targets username and password and send them to us using the corresponding form in this page (only visible to registered users) or contact us.

External resources for this compound

Bibliographic References

No literature references available for this target.

If you have references for this compound, please enter them in a user comment (below) or Contact us.