Detailed information for compound 1464766

Basic information

Technical information
  • Name: Unnamed compound
  • MW: 264.36 | Formula: C16H24O3
  • H donors: 1 H acceptors: 2 LogP: 2.9 Rotable bonds: 3
    Rule of 5 violations (Lipinski): 1
  • SMILES: C[C@@H](CC[C@@H]1[C@@]2([C@@]1(C)C[C@H]1[C@@H](C2)OC(=O)C1=C)C)O
  • InChi: 1S/C16H24O3/c1-9(17)5-6-13-15(3)7-11-10(2)14(18)19-12(11)8-16(13,15)4/h9,11-13,17H,2,5-8H2,1,3-4H3/t9-,11+,12+,13-,15-,16+/m0/s1
  • InChiKey: FDFBRCKWUMZDTG-AYWPFRTFSA-N  


Substructure search Similarity search

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Synonyms

No synonyms found for this compound

Targets

Known targets for this compound

No curated genes were found associated with this compound

Predicted pathogen targets for this compound

By orthology
No druggable targets predicted by orthology data
By sequence similarity to non orthologous known druggable targets
No druggable targets predicted by sequence similarity
Obtained from network model

Ranking Plot

Putative Targets List

Species Potential target Raw Global Species
Entamoeba histolytica phosphatidylinositol 3-kinase 3, putative 0.0264 0.0147 0.1796
Leishmania major 4-coumarate:coa ligase-like protein 0.0051 0.0011 0.0014
Trichomonas vaginalis PIKK family atypical protein kinase 0.1258 0.078 0.7957
Echinococcus granulosus potassium voltage gated channel protein 0.0467 0.0276 0.0276
Mycobacterium ulcerans flavin-containing monoamine oxidase AofH 0.2987 0.1881 1
Onchocerca volvulus 0.0264 0.0147 0.5211
Entamoeba histolytica hypothetical protein 0.0742 0.0451 0.5586
Echinococcus multilocularis potassium voltage gated channel subfamily H 0.0541 0.0323 0.0323
Echinococcus granulosus two pore calcium channel protein 2 0.0467 0.0276 0.0276
Plasmodium falciparum 3',5'-cyclic nucleotide phosphodiesterase, putative 0.0133 0.0063 0.2834
Brugia malayi Voltage-gated potassium channel, Shab-family (KCNB, Kv2-like) alpha-subunit. C. elegans exp-2 ortholog 0.0467 0.0276 0.1024
Mycobacterium tuberculosis Possible penicillin-binding protein 0.0693 0.042 0.2397
Schistosoma mansoni niemann-pick C1 (NPC1) 0.0111 0.0049 0.0501
Mycobacterium ulcerans putative regulatory protein 0.0345 0.0199 0.1042
Schistosoma mansoni serine/threonine protein kinase 0.1571 0.0979 1
Trichomonas vaginalis calcium/calmodulin-dependent 3,5-cyclic nucleotide phosphodiesterase, putative 0.0479 0.0283 0.2852
Trypanosoma brucei cytochrome P450, putative 0.0087 0.0034 0.0291
Plasmodium falciparum lysine-specific histone demethylase 1, putative 0.021 0.0113 0.5127
Echinococcus granulosus phosphatidylinositol 4 kinase beta 0.0264 0.0147 0.0147
Trypanosoma brucei cAMP phosphodiesterase A, putative 0.0133 0.0063 0.0592
Loa Loa (eye worm) ion channel NompC 0.0467 0.0276 0.1058
Mycobacterium ulcerans cytochrome P450 188A3 Cyp188A3 0.0067 0.0021 0.0098
Mycobacterium ulcerans cytochrome P450 143A4 Cyp143A4 0.0067 0.0021 0.0098
Echinococcus multilocularis potassium voltage gated channel protein 0.0467 0.0276 0.0276
Echinococcus granulosus PIK kinase FAT and Armadillo domain containing protein 0.0524 0.0313 0.0313
Echinococcus granulosus phosphatidylinositol 4 kinase alpha 0.0374 0.0217 0.0217
Schistosoma mansoni high voltage-activated calcium channel Cav1 0.0467 0.0276 0.282
Mycobacterium tuberculosis Possible cytochrome P450 135B1 Cyp135B1 0.0067 0.0021 0.0113
Trichomonas vaginalis phosphatidylinositol 3-kinase catalytic subunit alpha, beta, delta, putative 0.0898 0.0551 0.56
Echinococcus multilocularis sodium leak channel non selective protein 0.0467 0.0276 0.0276
Loa Loa (eye worm) hypothetical protein 0.0788 0.0481 0.1845
Trypanosoma cruzi hypothetical protein, conserved 0.0133 0.0063 0.0166
Schistosoma mansoni tyrosine kinase 0.0709 0.043 0.4396
Trichomonas vaginalis conserved hypothetical protein 0.0524 0.0313 0.3153
Mycobacterium tuberculosis Probable cytochrome P450 128 Cyp128 0.0067 0.0021 0.0113
Trichomonas vaginalis conserved hypothetical protein 0.0133 0.0063 0.0592
Mycobacterium leprae conserved hypothetical protein 0.0108 0.0048 0.1959
Entamoeba histolytica fructose-1,6-bisphosphate aldolase, putative 0.0302 0.0171 0.2099
Loa Loa (eye worm) phosphatidylinositol 3 0.0248 0.0137 0.0522
Echinococcus granulosus transient receptor potential cation channel 0.0467 0.0276 0.0276
Entamoeba histolytica Ulp1 protease family, C-terminal catalytic domain containing protein 0.0043 0.0006 0.0044
Echinococcus multilocularis sodium channel protein 0.3467 0.2186 0.2186
Mycobacterium ulcerans oxidoreductase 0.021 0.0113 0.0585
Brugia malayi Immunoglobulin I-set domain containing protein 0.0094 0.0039 0.014
Schistosoma mansoni vesicular amine transporter 0.0467 0.0276 0.282
Trichomonas vaginalis PIKK family atypical protein kinase 0.126 0.0781 0.7968
Echinococcus granulosus potassium voltage gated channel protein 0.0467 0.0276 0.0276
Schistosoma mansoni transient receptor potential cation channel subfamily m member 0.0467 0.0276 0.282
Loa Loa (eye worm) immunoglobulin I-set domain-containing protein 0.0094 0.0039 0.0144
Echinococcus granulosus survival motor neuron protein 1 0.0234 0.0128 0.0128
Echinococcus multilocularis expressed conserved protein 0.0149 0.0074 0.0074
Trypanosoma brucei mitogen activated protein kinase 4, putative 0.1571 0.0979 1
Trichomonas vaginalis rod cGMP-specific 3,5-cyclic phosphodiesterase, putative 0.0479 0.0283 0.2852
Mycobacterium ulcerans esterase/lipase LipP 0.0108 0.0048 0.0239
Mycobacterium ulcerans cytochrome P450 124A1, Cyp124A1 0.0067 0.0021 0.0098
Echinococcus multilocularis short transient receptor potential channel 6 0.0467 0.0276 0.0276
Trichomonas vaginalis cGMP-dependent 3,5-cyclic phosphodiesterase, putative 0.0479 0.0283 0.2852
Loa Loa (eye worm) hypothetical protein 0.0043 0.0006 0.0019
Mycobacterium tuberculosis Possible cytochrome P450 126 Cyp126 0.0067 0.0021 0.0113
Loa Loa (eye worm) voltage-gated potassium channel 0.0467 0.0276 0.1058
Toxoplasma gondii phosphatidylinositol 3- and 4-kinase 0.0264 0.0147 0.1447
Brugia malayi Cytochrome P450 family protein 0.0087 0.0034 0.0124
Plasmodium falciparum conserved Plasmodium protein, unknown function 0.021 0.0113 0.5127
Echinococcus granulosus potassium voltage gated channel subfamily A 0.0467 0.0276 0.0276
Leishmania major cytochrome p450-like protein 0.0087 0.0034 0.0078
Toxoplasma gondii phosphatidylinositol 3- and 4-kinase 0.0374 0.0217 0.2169
Schistosoma mansoni voltage-gated potassium channel 0.0467 0.0276 0.282
Schistosoma mansoni tumor necrosis factor receptor related 0.0144 0.007 0.0717
Trichomonas vaginalis PIKK family atypical protein kinase 0.0711 0.0431 0.4373
Trichomonas vaginalis high-affinity cGMP-specific 3,5-cyclic phosphodiesterase, putative 0.0479 0.0283 0.2852
Trypanosoma cruzi phosphatidylinositol 3-kinase 2, putative 0.111 0.0685 0.196
Loa Loa (eye worm) phosphatidylinositol 4-kinase type 3 alpha isoform 1 0.0374 0.0217 0.083
Echinococcus multilocularis p2X purinoceptor 4 0.0076 0.0027 0.0027
Loa Loa (eye worm) hypothetical protein 0.0038 0.0003 0.0007
Trypanosoma cruzi cyclic nucleotide phosphodiesterase 0.0133 0.0063 0.0166
Schistosoma mansoni voltage-gated cation channel 0.0467 0.0276 0.282
Schistosoma mansoni hypothetical protein 0.0037 0.0002 0.0024
Leishmania major hypothetical protein, conserved 0.0108 0.0048 0.0115
Loa Loa (eye worm) voltage-dependent calcium channel 0.0467 0.0276 0.1058
Trichomonas vaginalis Clan CE, family C48, Ulp1-like cysteine peptidase 0.0102 0.0044 0.0387
Entamoeba histolytica Niemann-Pick C1 protein, putative 0.0109 0.0048 0.0568
Mycobacterium tuberculosis Probable cytochrome P450 140 Cyp140 0.0067 0.0021 0.0113
Echinococcus granulosus high affinity cgmp specific 3' 5' cyclic 0.0133 0.0063 0.0063
Toxoplasma gondii transporter, cation channel family protein 0.0467 0.0276 0.2777
Trichomonas vaginalis PIKK family atypical protein kinase 0.1235 0.0765 0.7806
Echinococcus multilocularis survival motor neuron protein 1 0.0234 0.0128 0.0128
Mycobacterium tuberculosis Probable cytochrome P450 124 Cyp124 0.0067 0.0021 0.0113
Loa Loa (eye worm) hypothetical protein 0.021 0.0113 0.0429
Mycobacterium ulcerans cytochrome P450 136A2 Cyp136A2 0.0067 0.0021 0.0098
Loa Loa (eye worm) hypothetical protein 0.0485 0.0287 0.1101
Trichomonas vaginalis PIKK family atypical protein kinase 0.1275 0.079 0.8065
Trichomonas vaginalis cyclic nucleotide phosphodiesterase, putative 0.0133 0.0063 0.0592
Schistosoma mansoni voltage-gated potassium channel 0.0485 0.0287 0.2936
Schistosoma mansoni hypothetical protein 0.0035 0.0001 0.0011
Brugia malayi Protein kinase domain containing protein 0.0422 0.0247 0.0917
Entamoeba histolytica phosphatidylinositol3-kinaseTor2, putative 0.13 0.0806 1
Schistosoma mansoni phosphatidylinositol-45-bisphosphate 3-kinase catalytic subunit alpha PI3K 0.0512 0.0305 0.3113
Mycobacterium ulcerans dehydrogenase 0.021 0.0113 0.0585
Echinococcus multilocularis potassium voltage gated channel subfamily A 0.0467 0.0276 0.0276
Brugia malayi Phosphatidylinositol 3- and 4-kinase family protein 0.0711 0.0431 0.1603
Leishmania major hypothetical protein, conserved 0.5749 0.364 1
Echinococcus granulosus transient receptor potential cation channel 0.0467 0.0276 0.0276
Loa Loa (eye worm) hypothetical protein 0.0467 0.0276 0.1058
Brugia malayi hypothetical protein 0.0234 0.0128 0.0472
Echinococcus multilocularis serine:threonine protein kinase SMG1 0.0711 0.0431 0.0431
Entamoeba histolytica Ulp1 protease family, C-terminal catalytic domain containing protein 0.0102 0.0044 0.0513
Trypanosoma cruzi Phosphatidylinositol 3-kinase tor1 0.13 0.0806 0.2309
Trichomonas vaginalis fructose-bisphosphate aldolase, putative 0.0302 0.0171 0.1698
Brugia malayi Voltage-gated potassium channel, HERG (KCNH2)-related. C. elegans unc-103 ortholog 0.0541 0.0323 0.12
Mycobacterium leprae PROBABLE PROTOPORPHYRINOGEN OXIDASE HEMY (PROTOPORPHYRINOGEN-IX OXIDASE) (PROTOPORPHYRINOGENASE) (PPO) 0.021 0.0113 0.5418
Loa Loa (eye worm) hypothetical protein 0.0467 0.0276 0.1058
Echinococcus granulosus potassium voltage gated channel subfamily H 0.0541 0.0323 0.0323
Echinococcus granulosus potassium voltage gated channel subfamily D 0.0467 0.0276 0.0276
Echinococcus multilocularis dual 3',5' cyclic AMP and GMP phosphodiesterase 0.0479 0.0283 0.0283
Echinococcus multilocularis tumor protein p63 0.0374 0.0217 0.0217
Schistosoma mansoni transient receptor potential channel 0.0467 0.0276 0.282
Brugia malayi Protein kinase domain containing protein 0.0108 0.0048 0.0174
Schistosoma mansoni voltage-gated potassium channel 0.0467 0.0276 0.282
Schistosoma mansoni hypothetical protein 0.0045 0.0007 0.0075
Schistosoma mansoni patched 1 0.0047 0.0008 0.0086
Loa Loa (eye worm) hypothetical protein 0.0478 0.0283 0.1084
Echinococcus multilocularis voltage gated potassium channel 0.0467 0.0276 0.0276
Brugia malayi cation channel family protein 0.0467 0.0276 0.1024
Echinococcus granulosus hypothetical protein 0.0467 0.0276 0.0276
Echinococcus granulosus cAMP specific 3'5' cyclic phosphodiesterase 0.0133 0.0063 0.0063
Schistosoma mansoni voltage-gated potassium channel 0.0467 0.0276 0.282
Trichomonas vaginalis cGMP-specific 3,5-cyclic phosphodiesterase, putative 0.0479 0.0283 0.2852
Loa Loa (eye worm) hypothetical protein 0.021 0.0113 0.0429
Trichomonas vaginalis PIKK family atypical protein kinase 0.1255 0.0778 0.7936
Echinococcus granulosus p2X purinoceptor 4 0.0076 0.0027 0.0027
Brugia malayi Hypothetical 52.5 kDa protein ZK945.1 in chromosome II, putative 0.0108 0.0048 0.0174
Echinococcus granulosus voltage dependent calcium channel type d subunit|voltage dependent calcium channel|voltage dependent L type calcium channel subu 0.0467 0.0276 0.0276
Mycobacterium ulcerans fatty-acid-CoA ligase 0.0051 0.0011 0.0044
Echinococcus multilocularis ankyrin repeat and death domain containing protein 0.0094 0.0039 0.0039
Brugia malayi Probable 3',5'-cyclic phosphodiesterase R153.1, putative 0.0133 0.0063 0.0233
Brugia malayi Voltage-gated potassium channel, Shaker-family (KCNA, Kv1-like) alpha-subunit 0.0467 0.0276 0.1024
Echinococcus granulosus phosphatidylinositol 45 bisphosphate 3 kinase 0.1481 0.0922 0.0922
Toxoplasma gondii cathepsin CPC1 0.0217 0.0117 0.1142
Echinococcus multilocularis Phosphatidylinositol 4 kinase type 2 beta 0.0264 0.0147 0.0147
Echinococcus multilocularis potassium voltage gated channel subfamily KQT 0.0467 0.0276 0.0276
Brugia malayi voltage-dependent calcium channel 0.0467 0.0276 0.1024
Schistosoma mansoni ataxia telangiectasia mutated (atm)-related 0.13 0.0806 0.8238
Loa Loa (eye worm) calcium channel 0.0467 0.0276 0.1058
Toxoplasma gondii cathepsin CPC2 0.0085 0.0033 0.0278
Echinococcus multilocularis sentrin specific protease 1 0.0043 0.0006 0.0006
Echinococcus granulosus lysine specific histone demethylase 1A 0.021 0.0113 0.0113
Trypanosoma brucei phosphatidylinositol kinase related protein, putative 0.0742 0.0451 0.4579
Loa Loa (eye worm) voltage-gated potassium channel 0.0467 0.0276 0.1058
Loa Loa (eye worm) hypothetical protein 0.0108 0.0048 0.0179
Toxoplasma gondii 3'5'-cyclic nucleotide phosphodiesterase domain-containing protein 0.0133 0.0063 0.0592
Echinococcus granulosus potassium voltage gated channel protein 0.0467 0.0276 0.0276
Trichomonas vaginalis conserved hypothetical protein 0.0345 0.0199 0.198
Echinococcus granulosus ankyrin repeat and death domain containing protein 0.0094 0.0039 0.0039
Echinococcus multilocularis insulin growth factor 1 receptor beta 0.0422 0.0247 0.0247
Trichomonas vaginalis Clan CA, family C1, cathepsin B-like cysteine peptidase 0.0137 0.0066 0.0614
Trypanosoma cruzi inositol 1,4,5-trisphosphate receptor, putative 0.0467 0.0276 0.078
Leishmania major hypothetical protein, unknown function 0.0264 0.0147 0.0387
Trypanosoma brucei 3', 5'-cyclic nucleotide phosphodiesterase, putative 0.0133 0.0063 0.0592
Brugia malayi hypothetical protein 0.0467 0.0276 0.1024
Loa Loa (eye worm) hypothetical protein 0.0108 0.0048 0.0179
Trypanosoma cruzi phosphatidylinositol 3-kinase, putative 0.0711 0.0431 0.1228
Trichomonas vaginalis phosphatidylinositol 3-kinase catalytic subunit alpha, beta, delta, putative 0.0512 0.0305 0.3071
Plasmodium vivax 3',5'-cyclic nucleotide phosphodiesterase, putative 0.0133 0.0063 0.2834
Brugia malayi CHE-14 protein 0.0047 0.0008 0.0027
Brugia malayi Voltage-gated calcium channel, L-type, alpha subunit. C. elegans egl-19 ortholog 0.0467 0.0276 0.1024
Mycobacterium tuberculosis Probable fructose-bisphosphate aldolase Fba 0.0148 0.0073 0.0408
Echinococcus granulosus Niemann Pick C1 protein 0.0156 0.0078 0.0078
Trypanosoma cruzi phosphatidylinositol kinase related protein, putative 0.0742 0.0451 0.1285
Echinococcus multilocularis FKBP12 rapamycin complex associated protein 0.13 0.0806 0.0806
Trypanosoma cruzi cAMP specific phosphodiesterase, putative 0.0133 0.0063 0.0166
Echinococcus granulosus cAMP and cAMP inhibited cGMP 3'5' cyclic 0.425 0.2685 0.2685
Brugia malayi hypothetical protein 0.0037 0.0002 0.0005
Loa Loa (eye worm) phosphatidylinositol 3 0.1258 0.078 0.2997
Trypanosoma cruzi Lanosterol 14-alpha demethylase 0.0067 0.0021 0.0044
Echinococcus granulosus potassium voltage gated channel subfamily D 0.0467 0.0276 0.0276
Trypanosoma brucei hypothetical protein, conserved 0.0133 0.0063 0.0592
Echinococcus granulosus shaker cognate 0.0467 0.0276 0.0276
Mycobacterium leprae conserved hypothetical protein 0.0264 0.0147 0.7236
Toxoplasma gondii 3'5'-cyclic nucleotide phosphodiesterase domain-containing protein 0.0133 0.0063 0.0592
Trichomonas vaginalis high-affinity cGMP-specific 3,5-cyclic phosphodiesterase, putative 0.0133 0.0063 0.0592
Echinococcus multilocularis 0.021 0.0113 0.0113
Echinococcus multilocularis p2X purinoceptor 4 0.0076 0.0027 0.0027
Schistosoma mansoni transient receptor potential cation channel subfamily m member 0.0467 0.0276 0.282
Echinococcus multilocularis potassium voltage gated channel protein 0.0467 0.0276 0.0276
Leishmania major cytochrome p450-like protein 0.0067 0.0021 0.0042
Loa Loa (eye worm) hypothetical protein 0.0467 0.0276 0.1058
Loa Loa (eye worm) hypothetical protein 0.021 0.0113 0.0429
Giardia lamblia Hypothetical protein 0.0133 0.0063 0.0592
Echinococcus multilocularis netrin receptor unc 5 0.0094 0.0039 0.0039
Loa Loa (eye worm) CMGC/MAPK/ERK1 protein kinase 0.1571 0.0979 0.3761
Mycobacterium ulcerans acyl-CoA synthetase 0.0051 0.0011 0.0044
Plasmodium falciparum cGMP-specific phosphodiesterase 0.0133 0.0063 0.2834
Brugia malayi Phosphatidylinositol 3- and 4-kinase family protein 0.1344 0.0834 0.3104
Mycobacterium tuberculosis Probable esterase/lipase LipP 0.0108 0.0048 0.0265
Trichomonas vaginalis cAMP-specific phosphodiesterase, putative 0.0479 0.0283 0.2852
Echinococcus multilocularis protein patched 0.0047 0.0008 0.0008
Loa Loa (eye worm) hypothetical protein 0.0479 0.0283 0.1086
Schistosoma mansoni ryanodine receptor related 0.0467 0.0276 0.282
Schistosoma mansoni cyclic-nucleotide-gated cation channel 0.0478 0.0283 0.2889
Entamoeba histolytica phosphatidylinositol 3-kinase, putative 0.111 0.0685 0.8494
Trichomonas vaginalis PIKK family atypical protein kinase 0.0775 0.0472 0.4794
Toxoplasma gondii 3'5'-cyclic nucleotide phosphodiesterase domain-containing protein 0.0133 0.0063 0.0592
Toxoplasma gondii hypothetical protein 0.0345 0.0199 0.198
Loa Loa (eye worm) hypothetical protein 0.0047 0.0008 0.0028
Mycobacterium tuberculosis Conserved protein 0.0108 0.0048 0.0265
Loa Loa (eye worm) pigment dispersing factor receptor c 0.0052 0.0011 0.004
Toxoplasma gondii 3'5'-cyclic nucleotide phosphodiesterase domain-containing protein 0.0133 0.0063 0.0592
Brugia malayi Phosphatidylinositol 3- and 4-kinase family protein 0.111 0.0685 0.2549
Schistosoma mansoni voltage-gated potassium channel KCNQ 0.0467 0.0276 0.282
Mycobacterium ulcerans cytochrome P450 150A6 Cyp150A6 0.0067 0.0021 0.0098
Echinococcus granulosus high affinity cAMP specific 3'5' cyclic 0.0133 0.0063 0.0063
Loa Loa (eye worm) hypothetical protein 0.0467 0.0276 0.1058
Echinococcus granulosus epidermal growth factor receptor 0.0709 0.043 0.043
Giardia lamblia Dipeptidyl-peptidase I precursor 0.0085 0.0033 0.0278
Trichomonas vaginalis PIKK family atypical protein kinase 0.1255 0.0778 0.7935
Trichomonas vaginalis voltage and ligand gated potassium channel, putative 0.0074 0.0026 0.0205
Loa Loa (eye worm) abnormal chemotaxis protein 14 0.0047 0.0008 0.0028
Trichomonas vaginalis PIKK family atypical protein kinase 0.1235 0.0765 0.7806
Trichomonas vaginalis high-affinity cGMP-specific 3,5-cyclic phosphodiesterase, putative 0.0479 0.0283 0.2852
Trypanosoma cruzi phosphatidylinositol 3-related kinase, putative 0.1344 0.0834 0.239
Loa Loa (eye worm) phosphatidylinositol 3 0.0264 0.0147 0.056
Mycobacterium tuberculosis Cytochrome P450 51 Cyp51 (CYPL1) (P450-L1A1) (sterol 14-alpha demethylase) (lanosterol 14-alpha demethylase) (P450-14DM) 0.0067 0.0021 0.0113
Trichomonas vaginalis PIKK family atypical protein kinase 0.1275 0.079 0.8065
Echinococcus multilocularis hyperpolarization activated cyclic 0.0478 0.0283 0.0283
Entamoeba histolytica acyl-CoA synthetase, putative 0.0051 0.0011 0.0107
Echinococcus granulosus Niemann Pick C1 protein 0.0109 0.0048 0.0048
Trypanosoma cruzi phosphatidylinositol 4-kinase, putative 0.0264 0.0147 0.0406
Echinococcus granulosus epidermal growth factor receptor 0.132 0.0819 0.0819
Trichomonas vaginalis cAMP and cAMP-inhibited cGMP 3,5-cyclic phosphodiesterase, putative 0.0133 0.0063 0.0592
Mycobacterium leprae Probable lipase LipE 0.0108 0.0048 0.1959
Mycobacterium ulcerans fusion of enoyl-CoA hydratase, EchA21 and lipase, LipE 0.0108 0.0048 0.0239
Brugia malayi Cytochrome P450 family protein 0.0067 0.0021 0.0075
Schistosoma mansoni 60S ribosomal protein L21 0.0474 0.0281 0.2868
Trypanosoma cruzi UDP-galactopyranose mutase 0.021 0.0113 0.0308
Echinococcus granulosus voltage dependent calcium channel type d subunit|voltage dependent calcium channel alpha 1 0.0467 0.0276 0.0276
Plasmodium falciparum dipeptidyl aminopeptidase 1 0.0217 0.0117 0.5332
Toxoplasma gondii transporter, cation channel family protein 0.0467 0.0276 0.2777
Mycobacterium ulcerans epoxide hydrolase EphA 0.016 0.0081 0.0414
Trichomonas vaginalis PIKK family atypical protein kinase 0.1255 0.0778 0.7935
Trichomonas vaginalis Clan CE, family C48, Ulp1-like cysteine peptidase 0.0102 0.0044 0.0387
Echinococcus multilocularis geminin 0.0179 0.0092 0.0092
Schistosoma mansoni P2X receptor subunit 0.0076 0.0027 0.0277
Entamoeba histolytica hypothetical protein 0.0264 0.0147 0.1796
Trypanosoma brucei 3', 5'-cyclic nucleotide phosphodiesterase, putative 0.0133 0.0063 0.0592
Schistosoma mansoni high-affinity cgmp-specific 35-cyclic phosphodiesterase 0.0133 0.0063 0.0648
Plasmodium vivax dipeptidyl aminopeptidase 2, putative 0.0217 0.0117 0.5332
Echinococcus granulosus short transient receptor potential channel 6 0.0467 0.0276 0.0276
Toxoplasma gondii 3'5'-cyclic nucleotide phosphodiesterase domain-containing protein 0.0133 0.0063 0.0592
Trichomonas vaginalis phosphatidylinositol kinase, putative 0.0512 0.0305 0.3071
Trichomonas vaginalis fructose-bisphosphate aldolase, putative 0.0302 0.0171 0.1698
Trypanosoma cruzi hypothetical protein, conserved 0.0133 0.0063 0.0166
Trypanosoma cruzi hypothetical protein, conserved 0.0108 0.0048 0.0121
Trypanosoma cruzi cAMP specific phosphodiesterase, putative 0.0479 0.0283 0.0801
Loa Loa (eye worm) hypothetical protein 0.0057 0.0015 0.0054
Trichomonas vaginalis phosphatidylinositol kinase, putative 0.0374 0.0217 0.2169
Schistosoma mansoni tyrosine kinase 0.0702 0.0426 0.4347
Trichomonas vaginalis CMGC family protein kinase 0.1571 0.0979 1
Trichomonas vaginalis phosphatidylinositol 4-kinase, putative 0.0374 0.0217 0.2169
Plasmodium vivax hypothetical protein, conserved 0.021 0.0113 0.5127
Schistosoma mansoni calcium channel voltage-dependent p/q type alpha 1a-related 0.0467 0.0276 0.282
Brugia malayi phosphatidylinositol 4-kinase, catalytic, alpha polypeptide 0.0374 0.0217 0.0804
Echinococcus multilocularis phosphatidylinositol 4 phosphate 3 kinase C2 0.0723 0.0439 0.0439
Trypanosoma brucei phosphatidylinositol 3-kinase tor, putative 0.0303 0.0172 0.1706
Schistosoma mansoni fkbp-rapamycin associated protein 0.0711 0.0431 0.4407
Toxoplasma gondii phosphatidylinositol 3- and 4-kinase 0.0264 0.0147 0.1447
Loa Loa (eye worm) cytochrome P450 0.0067 0.0021 0.0077
Entamoeba histolytica phosphatidylinositol 3-kinase, putative 0.0512 0.0305 0.3761
Giardia lamblia CAMP-specific 3,5-cyclic phosphodiesterase 4B 0.0133 0.0063 0.0592
Loa Loa (eye worm) cyclic-nucleotide gated cation channel 0.0478 0.0283 0.1084
Trichomonas vaginalis cyclic nucleotide phosphodiesterase, putative 0.0479 0.0283 0.2852
Giardia lamblia Kinase, CMGC MAPK 0.1571 0.0979 1
Trichomonas vaginalis cyclic nucleotide phosphodiesterase, putative 0.0133 0.0063 0.0592
Trichomonas vaginalis PIKK family atypical protein kinase 0.13 0.0806 0.8227
Loa Loa (eye worm) hypothetical protein 0.0108 0.0048 0.0179
Trichomonas vaginalis fructose-bisphosphate aldolase, putative 0.0302 0.0171 0.1698
Mycobacterium tuberculosis Conserved hypothetical protein 0.021 0.0113 0.0637
Brugia malayi Probable 3',5'-cyclic phosphodiesterase T04D3.3, putative 0.0133 0.0063 0.0233
Schistosoma mansoni camp/cgmp cyclic nucleotide phosphodiesterase 0.0479 0.0283 0.2895
Loa Loa (eye worm) hypothetical protein 0.0467 0.0276 0.1058
Loa Loa (eye worm) Ulp1 protease 0.0102 0.0044 0.0164
Loa Loa (eye worm) hypothetical protein 0.0467 0.0276 0.1058
Brugia malayi 3'5'-cyclic nucleotide phosphodiesterase family protein 0.0133 0.0063 0.0233
Echinococcus granulosus calcium:calmodulin dependent 3'5' cyclic 0.0133 0.0063 0.0063
Loa Loa (eye worm) hypothetical protein 0.0108 0.0048 0.0179
Schistosoma mansoni survival motor neuron protein 0.0048 0.0009 0.0092
Trichomonas vaginalis cyclic nucleotide phosphodiesterase, putative 0.0479 0.0283 0.2852
Brugia malayi Cyclic-nucleotide gated cation channel 0.0478 0.0283 0.1049
Echinococcus multilocularis calcium activated potassium channel 0.0481 0.0285 0.0285
Trichomonas vaginalis conserved hypothetical protein 0.0345 0.0199 0.198
Schistosoma mansoni hyperpolarization activated cyclic nucleotide-gated potassium channel 0.0478 0.0283 0.2889
Echinococcus granulosus transient receptor potential cation channel 0.0467 0.0276 0.0276
Schistosoma mansoni P2X receptor subunit 0.0076 0.0027 0.0277
Echinococcus multilocularis sterol regulatory element binding protein 0.0047 0.0008 0.0008
Loa Loa (eye worm) hypothetical protein 0.0038 0.0003 0.0007
Echinococcus granulosus voltage gated sodium channel Nav1 alpha subunit 0.3467 0.2186 0.2186
Toxoplasma gondii 3'5'-cyclic nucleotide phosphodiesterase domain-containing protein 0.0133 0.0063 0.0592
Echinococcus granulosus expressed conserved protein 0.0149 0.0074 0.0074
Plasmodium vivax dipeptidyl aminopeptidase 1, putative 0.0217 0.0117 0.5332
Loa Loa (eye worm) TK/INSR protein kinase 0.0422 0.0247 0.0947
Plasmodium vivax sentrin-specific protease 2, putative 0.0043 0.0006 0.0146
Trypanosoma cruzi target of rapamycin kinase 3 0.128 0.0794 0.2273
Trypanosoma cruzi phosphatidylinositol 3-kinase vps34-like 0.0512 0.0305 0.0862
Entamoeba histolytica hypothetical protein 0.0264 0.0147 0.1796
Trichomonas vaginalis phopsphatidylinositol 3-kinase, drosophila, putative 0.111 0.0685 0.6983
Trichomonas vaginalis cGMP-dependent 3,5-cyclic phosphodiesterase, putative 0.0133 0.0063 0.0592
Entamoeba histolytica Ulp1 protease family, C-terminal catalytic domain containing protein 0.0043 0.0006 0.0044
Leishmania major phosphatidylinositol 3-related kinase, putative 0.1258 0.078 0.213
Loa Loa (eye worm) phosphatidylinositol 3 0.0264 0.0147 0.056
Echinococcus granulosus beta LACTamase domain containing family member 0.0108 0.0048 0.0048
Mycobacterium ulcerans beta-lactamase 0.0108 0.0048 0.0239
Echinococcus granulosus Phosphatidylinositol 4 kinase type 2 beta 0.0264 0.0147 0.0147
Echinococcus multilocularis transient receptor potential cation channel 0.0467 0.0276 0.0276
Echinococcus multilocularis transient receptor potential cation channel 0.0467 0.0276 0.0276
Trichomonas vaginalis PIKK family atypical protein kinase 0.13 0.0806 0.8227
Trichomonas vaginalis cone cGMP-specific 3,5-cyclic phosphodiesterase, putative 0.0479 0.0283 0.2852
Trichomonas vaginalis cAMP/cGMP cyclic nucleotide phosphodiesterase, putative 0.0479 0.0283 0.2852
Trypanosoma cruzi mitogen-activated protein kinase 11, putative 0.1571 0.0979 0.2807
Echinococcus multilocularis mitogen activated protein kinase 0.1571 0.0979 0.0979
Echinococcus granulosus netrin receptor unc 5 0.0094 0.0039 0.0039
Echinococcus multilocularis p2X purinoceptor 4 0.0076 0.0027 0.0027
Schistosoma mansoni hypothetical protein 0.0045 0.0007 0.0075
Trichomonas vaginalis PIKK family atypical protein kinase 0.0447 0.0263 0.2646
Loa Loa (eye worm) hypothetical protein 0.0051 0.0011 0.0038
Schistosoma mansoni camp-specific cyclic nucleotide phosphodiesterase 0.0133 0.0063 0.0648
Brugia malayi Phosphatidylinositol 3- and 4-kinase family protein 0.0742 0.0451 0.1678
Echinococcus granulosus transient receptor potential cation channel 0.0467 0.0276 0.0276
Echinococcus multilocularis two pore calcium channel protein 2 0.0467 0.0276 0.0276
Echinococcus multilocularis Niemann Pick C1 protein 0.0156 0.0078 0.0078
Trypanosoma brucei phosphatidylinositol 3-related kinase, putative 0.1258 0.078 0.7957
Loa Loa (eye worm) hypothetical protein 0.021 0.0113 0.0429
Loa Loa (eye worm) hypothetical protein 0.0478 0.0283 0.1086
Trypanosoma brucei FAT domain/Rapamycin binding domain/Phosphatidylinositol 3- and 4-kinase, putative 0.0808 0.0493 0.501
Trichomonas vaginalis high-affinity cGMP-specific 3,5-cyclic phosphodiesterase, putative 0.0479 0.0283 0.2852
Entamoeba histolytica phosphatidylinositol 3-kinase 1, putative 0.0846 0.0517 0.6404
Trichomonas vaginalis PIKK family atypical protein kinase 0.1275 0.079 0.8065
Echinococcus granulosus mitogen activated protein kinase 0.1571 0.0979 0.0979
Schistosoma mansoni family S12 unassigned peptidase (S12 family) 0.0108 0.0048 0.0487
Trichomonas vaginalis phosphatidylinositol 3-kinase class, putative 0.0512 0.0305 0.3071
Loa Loa (eye worm) hypothetical protein 0.0133 0.0063 0.024
Mycobacterium ulcerans cytochrome P450 105Q4 Cyp105Q4 0.0067 0.0021 0.0098
Mycobacterium tuberculosis Possible oxidoreductase 0.021 0.0113 0.0637
Trichomonas vaginalis conserved hypothetical protein 0.0345 0.0199 0.198
Brugia malayi AMP-binding enzyme family protein 0.0051 0.0011 0.0037
Loa Loa (eye worm) hypothetical protein 0.0524 0.0313 0.1199
Echinococcus multilocularis two pore calcium channel protein 1 0.0467 0.0276 0.0276
Plasmodium falciparum phosphodiesterase gamma, putative 0.0133 0.0063 0.2834
Brugia malayi Voltage-gated potassium channel, KCNQ (Kv7-like) alpha-subunit. C. elegans kqt-1 ortholog 0.0467 0.0276 0.1024
Echinococcus granulosus potassium voltage gated channel subfamily D 0.0467 0.0276 0.0276
Plasmodium vivax hypothetical protein, conserved 0.0108 0.0048 0.2097
Echinococcus granulosus geminin 0.0179 0.0092 0.0092
Echinococcus multilocularis cyclic nucleotide gated cation channel alpha 3 0.0478 0.0283 0.0283
Brugia malayi Phosphatidylinositol 3- and 4-kinase family protein 0.0264 0.0147 0.0542
Echinococcus multilocularis conserved hypothetical protein 0.0467 0.0276 0.0276
Entamoeba histolytica acyl-CoA synthetase, putative 0.0051 0.0011 0.0107
Echinococcus granulosus sentrin specific protease 7 0.0192 0.0101 0.0101
Giardia lamblia Dipeptidyl-peptidase I precursor 0.0217 0.0117 0.1142
Schistosoma mansoni Lysine-specific histone demethylase 1 0.021 0.0113 0.115
Plasmodium vivax hypothetical protein, conserved 0.021 0.0113 0.5127
Echinococcus multilocularis TRP (transient receptor potential) channel 0.0467 0.0276 0.0276
Trichomonas vaginalis PIKK family atypical protein kinase 0.1255 0.0778 0.7935
Brugia malayi Voltage-gated calcium channel, P/Q-type, alpha subunit. C. elegans unc-2 ortholog 0.0467 0.0276 0.1024
Toxoplasma gondii transporter, cation channel family protein 0.0467 0.0276 0.2777
Echinococcus granulosus death domain containing protein 0.0094 0.0039 0.0039
Mycobacterium tuberculosis Cytochrome P450 121 Cyp121 0.0067 0.0021 0.0113
Schistosoma mansoni camp-specific 35-cyclic phosphodiesterase 0.0133 0.0063 0.0648
Echinococcus granulosus insulin growth factor 1 receptor beta 0.0422 0.0247 0.0247
Mycobacterium leprae Conserved hypothetical protein 0.0067 0.0021 0.0543
Echinococcus granulosus neuropeptide s receptor 0.0937 0.0576 0.0576
Loa Loa (eye worm) hypothetical protein 0.0038 0.0003 0.0007
Loa Loa (eye worm) hypothetical protein 0.0467 0.0276 0.1058
Leishmania major phosphatidylinositol 4-kinase alpha, putative 0.0374 0.0217 0.0581
Loa Loa (eye worm) hypothetical protein 0.0467 0.0276 0.1058
Plasmodium vivax hypothetical protein 0.0264 0.0147 0.6719
Plasmodium falciparum phosphatidylinositol 4-kinase 0.0264 0.0147 0.6719
Toxoplasma gondii 3'5'-cyclic nucleotide phosphodiesterase domain-containing protein 0.0133 0.0063 0.0592
Plasmodium vivax cyclic nucleotide phosphodiesterase, putative 0.0133 0.0063 0.2834
Toxoplasma gondii 3'5'-cyclic nucleotide phosphodiesterase domain-containing protein 0.06 0.0361 0.3649
Plasmodium vivax phosphatidylinositol 4-kinase, putative 0.0264 0.0147 0.6719
Schistosoma mansoni high-affinity cgmp-specific 35-cyclic phosphodiesterase 0.0133 0.0063 0.0648
Echinococcus granulosus voltage dependent calcium channel 0.0467 0.0276 0.0276
Trichomonas vaginalis fructose-bisphosphate aldolase, putative 0.0302 0.0171 0.1698
Entamoeba histolytica FKBP-rapamycin associated protein (FRAP), putative 0.13 0.0806 1
Toxoplasma gondii CMGC kinase, MAPK family (ERK) MAPK-1 0.1571 0.0979 1
Loa Loa (eye worm) cytochrome P450 family protein 0.0087 0.0034 0.0128
Schistosoma mansoni voltage-gated potassium channel 0.0549 0.0328 0.3351
Trichomonas vaginalis fructose-bisphosphate aldolase, putative 0.0302 0.0171 0.1698
Schistosoma mansoni phosphatidylinositol-45-bisphosphate 3-kinase catalytic subunit alpha PI3K 0.0374 0.0217 0.2216
Brugia malayi Ulp1 protease family, C-terminal catalytic domain containing protein 0.0102 0.0044 0.0158
Trypanosoma brucei hypothetical protein, conserved 0.0108 0.0048 0.043
Schistosoma mansoni voltage-gated potassium channel 0.0467 0.0276 0.282
Schistosoma mansoni family C48 unassigned peptidase (C48 family) 0.0102 0.0044 0.0445
Mycobacterium ulcerans cytochrome P450 125A7 Cyp125A7 0.0067 0.0021 0.0098
Schistosoma mansoni voltage-dependent calcium channel 0.0467 0.0276 0.282
Loa Loa (eye worm) MH2 domain-containing protein 0.0123 0.0057 0.0216
Schistosoma mansoni amine oxidase 0.021 0.0113 0.115
Trichomonas vaginalis conserved hypothetical protein 0.0133 0.0063 0.0592
Echinococcus multilocularis potassium voltage gated channel protein 0.0467 0.0276 0.0276
Trypanosoma cruzi hypothetical protein, conserved 0.5485 0.3472 1
Loa Loa (eye worm) hypothetical protein 0.0094 0.0039 0.0144
Loa Loa (eye worm) hypothetical protein 0.0052 0.0011 0.004
Toxoplasma gondii preprocathepsin c precursor, putative 0.0217 0.0117 0.1142
Brugia malayi Death domain containing protein 0.0094 0.0039 0.014
Echinococcus granulosus short transient receptor potential channel 6 0.0467 0.0276 0.0276
Schistosoma mansoni cyclic-nucleotide-gated cation channel 0.0478 0.0283 0.2889
Echinococcus granulosus tumor protein p63 0.0374 0.0217 0.0217
Trichomonas vaginalis PIKK family atypical protein kinase 0.13 0.0806 0.8227
Toxoplasma gondii 3'5'-cyclic nucleotide phosphodiesterase domain-containing protein 0.0133 0.0063 0.0592
Mycobacterium tuberculosis Probable conserved lipoprotein 0.0108 0.0048 0.0265
Toxoplasma gondii 3'5'-cyclic nucleotide phosphodiesterase domain-containing protein 0.0133 0.0063 0.0592
Trichomonas vaginalis voltage and ligand gated potassium channel, putative 0.0478 0.0283 0.2846
Brugia malayi AMP-binding enzyme family protein 0.0051 0.0011 0.0037
Schistosoma mansoni tyrosine kinase 0.132 0.0819 0.837
Loa Loa (eye worm) hypothetical protein 0.0108 0.0048 0.0179
Entamoeba histolytica Ulp1 protease family, C-terminal catalytic domain containing protein 0.0043 0.0006 0.0044
Echinococcus multilocularis lysine specific histone demethylase 1A 0.021 0.0113 0.0113
Schistosoma mansoni transient receptor potential channel 0.0467 0.0276 0.282
Echinococcus multilocularis potassium voltage gated channel subfamily C 0.0467 0.0276 0.0276
Echinococcus granulosus cytochrome P450 2K1 0.0067 0.0021 0.0021
Echinococcus multilocularis phosphatidylinositol 3 and 4 kinase 0.1344 0.0834 0.0834
Echinococcus multilocularis Basic leucine zipper (bZIP) transcription 0.0037 0.0002 0.0002
Brugia malayi Voltage-gated potassium channel, EAG (KCNH1)-related. C. elegans egl-2 ortholog 0.0485 0.0287 0.1067
Trichomonas vaginalis PIKK family atypical protein kinase 0.1275 0.079 0.8065
Brugia malayi Calcitonin receptor-like protein seb-1 0.0052 0.0011 0.0039
Mycobacterium tuberculosis Probable hydrolase 0.0108 0.0048 0.0265
Echinococcus granulosus potassium voltage gated channel protein 0.0467 0.0276 0.0276
Trichomonas vaginalis PIKK family atypical protein kinase 0.0755 0.046 0.4664
Toxoplasma gondii 3'5'-cyclic nucleotide phosphodiesterase domain-containing protein 0.06 0.0361 0.3649
Schistosoma mansoni ataxia telangiectasia mutated (atm) 0.0742 0.0451 0.4612
Echinococcus granulosus transient receptor potential cation channel 0.0467 0.0276 0.0276
Trichomonas vaginalis PIKK family atypical protein kinase 0.128 0.0794 0.8097
Trypanosoma cruzi Lanosterol 14-alpha demethylase 0.0067 0.0021 0.0044
Schistosoma mansoni tyrosine kinase 0.0709 0.043 0.4396
Trypanosoma cruzi phosphatidylinositol 4-kinase, putative 0.0264 0.0147 0.0406
Trichomonas vaginalis D-aminoacylase, putative 0.0108 0.0048 0.043
Schistosoma mansoni transcription factor LCR-F1 0.0037 0.0002 0.0024
Leishmania major hypothetical protein, conserved 0.0133 0.0063 0.0158
Trichomonas vaginalis cAMP-specific phosphodiesterase, putative 0.0479 0.0283 0.2852
Trichomonas vaginalis PIKK family atypical protein kinase 0.0734 0.0446 0.4524
Schistosoma mansoni ankyrin 23/unc44 0.0094 0.0039 0.0394
Loa Loa (eye worm) calcium/calmodulin-stimulated cyclic nucleotide phosphodiesterase 0.0133 0.0063 0.024
Mycobacterium ulcerans cytochrome P450 143A3 Cyp143A3 0.0067 0.0021 0.0098
Trichomonas vaginalis cGMP-dependent 3,5-cyclic phosphodiesterase, putative 0.0479 0.0283 0.2852
Trypanosoma cruzi phosphatidylinositol 3-kinase, putative 0.0264 0.0147 0.0406
Echinococcus multilocularis hyperpolarization activated cyclic 0.0478 0.0283 0.0283
Loa Loa (eye worm) hypothetical protein 0.0055 0.0013 0.0048
Trichomonas vaginalis PIKK family atypical protein kinase 0.126 0.0781 0.7968
Toxoplasma gondii target of rapamycin (TOR), putative 0.1275 0.079 0.8065
Leishmania major mitogen activated protein kinase 4, putative;with=GeneDB:LmxM19.1440 0.1571 0.0979 0.2677
Onchocerca volvulus 0.0264 0.0147 0.5211
Echinococcus granulosus TNFR CD27 30 40 95 cysteine rich region 0.0144 0.007 0.007
Echinococcus multilocularis transient receptor potential cation channel 0.0467 0.0276 0.0276
Loa Loa (eye worm) hypothetical protein 0.0094 0.0039 0.0144
Loa Loa (eye worm) hypothetical protein 0.0723 0.0439 0.1686
Echinococcus multilocularis voltage gated potassium channel 0.0485 0.0287 0.0287
Plasmodium vivax phosphatidylinositol 4-kinase, putative 0.0264 0.0147 0.6719
Echinococcus granulosus voltage dependent L type calcium channel subunit|voltage dependent calcium channel 0.0467 0.0276 0.0276
Trichomonas vaginalis PIKK family atypical protein kinase 0.075 0.0456 0.4631
Echinococcus granulosus insulin receptor 0.0422 0.0247 0.0247
Loa Loa (eye worm) PDE1B protein 0.0133 0.0063 0.024
Chlamydia trachomatis protoporphyrinogen oxidase 0.021 0.0113 1
Loa Loa (eye worm) hypothetical protein 0.0467 0.0276 0.1058
Giardia lamblia Phosphoinositide-3-kinase, catalytic, alpha polypeptide 0.076 0.0463 0.4698
Echinococcus granulosus Ankyrin 0.0094 0.0039 0.0039
Brugia malayi amine oxidase, flavin-containing family protein 0.021 0.0113 0.0415
Brugia malayi Phosphatidylinositol 3- and 4-kinase family protein 0.13 0.0806 0.3
Echinococcus multilocularis potassium voltage gated channel subfamily D 0.0467 0.0276 0.0276
Echinococcus multilocularis Phosphatidylinositol 4 kinase type 2 beta 0.0264 0.0147 0.0147
Trichomonas vaginalis rod cGMP-specific 3,5-cyclic phosphodiesterase, putative 0.0479 0.0283 0.2852
Schistosoma mansoni transient receptor potential cation channel subfamily m member 0.0467 0.0276 0.282
Schistosoma mansoni voltage-gated potassium channel 0.0474 0.0281 0.2868
Schistosoma mansoni camp-specific 35-cyclic phosphodiesterase 0.0133 0.0063 0.0648
Plasmodium falciparum sentrin-specific protease 1 0.0043 0.0006 0.0146
Trichomonas vaginalis high-affinity cGMP-specific 3,5-cyclic phosphodiesterase, putative 0.0133 0.0063 0.0592
Echinococcus multilocularis epidermal growth factor receptor 0.132 0.0819 0.0819
Plasmodium falciparum protoporphyrinogen oxidase 0.021 0.0113 0.5127
Trypanosoma cruzi Phosphatidylinositol 3-kinase tor2 0.13 0.0806 0.2309
Trichomonas vaginalis PIKK family atypical protein kinase 0.0833 0.0509 0.5171
Echinococcus granulosus phosphatidylinositol 4 phosphate 3 kinase C2 0.0723 0.0439 0.0439
Echinococcus multilocularis 0.0264 0.0147 0.0147
Loa Loa (eye worm) hypothetical protein 0.0038 0.0003 0.0007
Echinococcus granulosus mitogen activated protein kinase 3 0.1571 0.0979 0.0979
Mycobacterium leprae Probable fructose bisphosphate aldolase Fba 0.0148 0.0073 0.329
Loa Loa (eye worm) cytochrome P450 family protein 0.0234 0.0127 0.0486
Treponema pallidum fructose-bisphosphate aldolase 0.0302 0.0171 0.5
Loa Loa (eye worm) hypothetical protein 0.0234 0.0128 0.0487
Loa Loa (eye worm) phosphatidylinositol 3 0.13 0.0806 0.3098
Mycobacterium tuberculosis Two component sensor histidine kinase DevS 0.0345 0.0199 0.1129
Plasmodium vivax phosphodiesterase gamma, putative 0.0133 0.0063 0.2834
Echinococcus multilocularis serine protein kinase ATM 0.0742 0.0451 0.0451
Brugia malayi Furin-like cysteine rich region family protein 0.132 0.0819 0.3048
Leishmania major cAMP-specific phosphodiesterase, putative 0.0133 0.0063 0.0158
Schistosoma mansoni hypothetical protein 0.0045 0.0007 0.0075
Schistosoma mansoni phosphatidylinositol 4-kinase 0.0374 0.0217 0.2216
Mycobacterium ulcerans hypothetical protein 0.0108 0.0048 0.0239
Trypanosoma cruzi cytochrome P450, putative 0.0087 0.0034 0.0082
Trypanosoma cruzi hypothetical protein, conserved 0.0133 0.0063 0.0166
Entamoeba histolytica hypothetical protein 0.0264 0.0147 0.1796
Trypanosoma cruzi hypothetical protein 0.0102 0.0044 0.0109
Echinococcus multilocularis ryanodine receptor 44f 0.0467 0.0276 0.0276
Mycobacterium ulcerans long-chain-fatty-acid-CoA ligase 0.0051 0.0011 0.0044
Loa Loa (eye worm) phosphatidylinositol 3 0.1343 0.0834 0.3204
Toxoplasma gondii phosphatidylinositol 3- and 4-kinase 0.0264 0.0147 0.1447
Trichomonas vaginalis CMGC family protein kinase 0.1571 0.0979 1
Echinococcus multilocularis cAMP specific 3',5' cyclic phosphodiesterase 0.0133 0.0063 0.0063
Mycobacterium ulcerans long-chain-fatty-acid--CoA ligase 0.0051 0.0011 0.0044
Trichomonas vaginalis conserved hypothetical protein 0.0345 0.0199 0.198
Toxoplasma gondii hypothetical protein 0.0467 0.0276 0.2777
Toxoplasma gondii histone lysine methyltransferase SET1 0.006 0.0017 0.0114
Echinococcus granulosus hyperpolarization activated cyclic 0.0478 0.0283 0.0283
Brugia malayi AMP-binding enzyme family protein 0.0051 0.0011 0.0037
Echinococcus multilocularis transient receptor potential gamma protein 0.0467 0.0276 0.0276
Mycobacterium tuberculosis Probable cytochrome P450 144 Cyp144 0.0067 0.0021 0.0113
Trichomonas vaginalis penicillin-binding protein, putative 0.0108 0.0048 0.043
Onchocerca volvulus 0.0108 0.0048 0.1547
Mycobacterium tuberculosis Probable cytochrome P450 132 Cyp132 0.0067 0.0021 0.0113
Echinococcus granulosus Basic leucine zipper bZIP transcription 0.0037 0.0002 0.0002
Brugia malayi Iron-sulfur cluster assembly accessory protein 0.0048 0.0009 0.003
Echinococcus multilocularis Zinc finger, PHD finger 0.0374 0.0217 0.0217
Trichomonas vaginalis PIKK family atypical protein kinase 0.128 0.0794 0.8097
Trichomonas vaginalis phopsphatidylinositol 3-kinase, drosophila, putative 0.0264 0.0147 0.1447
Schistosoma mansoni hypothetical protein 0.0179 0.0092 0.0943
Trichomonas vaginalis PIKK family atypical protein kinase 0.1255 0.0778 0.7936
Leishmania major hypothetical protein, unknown function 0.0467 0.0276 0.0744
Trichomonas vaginalis fructose-bisphosphate aldolase, putative 0.0302 0.0171 0.1698
Mycobacterium ulcerans flavin-containing monoamine oxidase AofH 0.2987 0.1881 1
Giardia lamblia Dipeptidyl-peptidase I precursor 0.0085 0.0033 0.0278
Echinococcus multilocularis phosphatidylinositol 4 kinase alpha 0.0374 0.0217 0.0217
Onchocerca volvulus 0.0108 0.0048 0.1547
Trypanosoma cruzi phosphatidylinositol 4-kinase alpha, putative 0.0374 0.0217 0.0609
Giardia lamblia Phosphoinositide-3-kinase, class 3 0.0402 0.0234 0.2349
Trichomonas vaginalis voltage and ligand gated potassium channel, putative 0.0478 0.0283 0.2846
Brugia malayi Large-conductance calcium-activated potassium channel Slo-1 (KCNMA) alpha subunit. C. elegans slo-1 ortholog 0.0467 0.0276 0.1024
Echinococcus multilocularis 0.0409 0.0239 0.0239
Trichomonas vaginalis PIKK family atypical protein kinase 0.0284 0.0159 0.1576
Toxoplasma gondii cytochrome p450 superfamily protein 0.0067 0.0021 0.0157
Echinococcus granulosus potassium voltage gated channel subfamily C 0.0467 0.0276 0.0276
Plasmodium falciparum phosphodiesterase delta, putative 0.0133 0.0063 0.2834
Trichomonas vaginalis D-aminoacylase, putative 0.0108 0.0048 0.043
Trichomonas vaginalis cAMP-specific 3,5-cyclic phosphodiesterase, putative 0.0479 0.0283 0.2852
Trypanosoma brucei inositol 1,4,5-trisphosphate receptor 0.0467 0.0276 0.2777
Brugia malayi Ryanodine Receptor TM 4-6 family protein 0.0467 0.0276 0.1024
Loa Loa (eye worm) cyclic-nucleotide gated cation channel 0.0478 0.0283 0.1084
Echinococcus granulosus hyperpolarization activated cyclic 0.0478 0.0283 0.0283
Echinococcus granulosus Phosphatidylinositol 4 kinase type 2 beta 0.0264 0.0147 0.0147
Mycobacterium tuberculosis Possible cytochrome P450 135A1 Cyp135A1 0.0067 0.0021 0.0113
Toxoplasma gondii 3'5'-cyclic nucleotide phosphodiesterase domain-containing protein 0.0133 0.0063 0.0592
Echinococcus granulosus potassium voltage gated channel subfamily H 0.0485 0.0287 0.0287
Trypanosoma brucei Lanosterol 14-alpha demethylase 0.0067 0.0021 0.0157
Mycobacterium ulcerans cytochrome p450 150 cyp150 0.0067 0.0021 0.0098
Schistosoma mansoni hypothetical protein 0.0179 0.0092 0.0943
Schistosoma mansoni voltage-gated potassium channel 0.0467 0.0276 0.282
Trypanosoma cruzi cAMP phosphodiesterase A, putative 0.0133 0.0063 0.0166
Trypanosoma cruzi mitogen activated protein kinase 2, putative 0.1571 0.0979 0.2807
Mycobacterium ulcerans long-chain fatty-acid CoA ligase 0.0051 0.0011 0.0044
Trichomonas vaginalis phosphatidylinositol kinase, putative 0.0264 0.0147 0.1447
Schistosoma mansoni phosphatidylinositol 3-kinase class 0.0264 0.0147 0.1498
Schistosoma mansoni voltage-gated potassium channel 0.0467 0.0276 0.282
Brugia malayi Corticotropin releasing factor receptor 2 precursor, putative 0.0052 0.0011 0.0039
Toxoplasma gondii 3'5'-cyclic nucleotide phosphodiesterase domain-containing protein 0.0133 0.0063 0.0592
Loa Loa (eye worm) beta-LACTamase domain containing family member 0.0108 0.0048 0.0179
Echinococcus multilocularis sentrin specific protease 7 0.0192 0.0101 0.0101
Plasmodium vivax hypothetical protein, conserved 0.0345 0.0199 0.914
Trichomonas vaginalis cGMP-specific 3,5-cyclic phosphodiesterase, putative 0.0479 0.0283 0.2852
Onchocerca volvulus 0.0467 0.0276 1
Echinococcus granulosus potassium voltage gated channel protein 0.0467 0.0276 0.0276
Entamoeba histolytica Ulp1 protease family, C-terminal catalytic domain containing protein 0.0192 0.0101 0.1226
Echinococcus granulosus calcium activated potassium channel 0.0481 0.0285 0.0285
Schistosoma mansoni family C48 unassigned peptidase (C48 family) 0.0192 0.0101 0.103
Trichomonas vaginalis calcium/calmodulin-dependent 3,5-cyclic nucleotide phosphodiesterase, putative 0.0479 0.0283 0.2852
Schistosoma mansoni family S12 unassigned peptidase (S12 family) 0.0108 0.0048 0.0487
Loa Loa (eye worm) hypothetical protein 0.0467 0.0276 0.1058
Echinococcus multilocularis potassium voltage gated channel subfamily D 0.0467 0.0276 0.0276
Echinococcus multilocularis protein dispatched 1 0.0053 0.0013 0.0013
Echinococcus granulosus voltage dependent calcium channel 0.0467 0.0276 0.0276
Echinococcus granulosus two pore calcium channel protein 1 0.0467 0.0276 0.0276
Brugia malayi Voltage-gated potassium channel, Shaw-family (KCNC, Kv3-like) alpha-subunit 0.0467 0.0276 0.1024
Schistosoma mansoni phosphatidylinositol 4-kinase type-II 0.0264 0.0147 0.1498
Entamoeba histolytica phosphatidylinositol 3-kinase, putative 0.0586 0.0351 0.4343
Echinococcus multilocularis potassium voltage gated channel subfamily D 0.0467 0.0276 0.0276
Mycobacterium tuberculosis Probable lipase LipE 0.0108 0.0048 0.0265
Plasmodium falciparum phosphatidylinositol 3-kinase 0.0374 0.0217 1
Loa Loa (eye worm) hypothetical protein 0.3772 0.2381 0.9154
Giardia lamblia Fructose-bisphosphate aldolase 0.0302 0.0171 0.1698
Brugia malayi Voltage-gated calcium channel, T-type, alpha subunit. C. elegans cca-1 ortholog 0.0467 0.0276 0.1024
Trichomonas vaginalis cAMP and cAMP-inhibited cGMP 3,5-cyclic phosphodiesterase, putative 0.0133 0.0063 0.0592
Toxoplasma gondii 3'5'-cyclic nucleotide phosphodiesterase domain-containing protein 0.0133 0.0063 0.0592
Brugia malayi Niemann-Pick C1 protein precursor 0.0109 0.0048 0.0175
Echinococcus granulosus transient receptor potential gamma protein 0.0467 0.0276 0.0276
Echinococcus multilocularis high affinity cgmp specific 3' 5' cyclic 0.0133 0.0063 0.0063
Mycobacterium tuberculosis Conserved protein 0.0108 0.0048 0.0265
Trypanosoma brucei phosphatidylinositol 4-kinase alpha, putative 0.0374 0.0217 0.2169
Mycobacterium tuberculosis Probable cytochrome P450 141 Cyp141 0.0067 0.0021 0.0113
Schistosoma mansoni voltage-gated potassium channel 0.0467 0.0276 0.282
Echinococcus granulosus cAMP specific 3'5' cyclic phosphodiesterase 0.0133 0.0063 0.0063
Trichomonas vaginalis PIKK family atypical protein kinase 0.0742 0.0451 0.4579
Schistosoma mansoni voltage-gated potassium channel 0.0478 0.0283 0.2889
Toxoplasma gondii ABC1 family protein 0.0108 0.0048 0.043
Loa Loa (eye worm) hypothetical protein 0.0043 0.0006 0.0019
Loa Loa (eye worm) TK/EGFR protein kinase 0.132 0.0819 0.3147
Echinococcus multilocularis calcium:calmodulin dependent 3',5' cyclic 0.0133 0.0063 0.0063
Schistosoma mansoni voltage-gated potassium channel 0.0467 0.0276 0.282
Toxoplasma gondii GAF domain-containing protein 0.0345 0.0199 0.198
Echinococcus granulosus lysine specific histone demethylase 1A 0.021 0.0113 0.0113
Echinococcus granulosus sterol regulatory element binding protein 0.0047 0.0008 0.0008
Schistosoma mansoni transient receptor potential channel 0.0467 0.0276 0.282
Echinococcus granulosus potassium channel KvQLT family member kqt 1 0.0467 0.0276 0.0276
Toxoplasma gondii FATC domain-containing protein 0.0742 0.0451 0.4579
Leishmania major calcium channel protein, putative,ion transporter, putative 0.3467 0.2186 0.6
Schistosoma mansoni mixed-lineage leukemia protein mll 0.0067 0.0022 0.022
Schistosoma mansoni amine oxidase 0.021 0.0113 0.115
Trypanosoma brucei phosphatidylinositol 4-kinase, putative 0.13 0.0806 0.8227
Leishmania major phosphatidylinositol 3-kinase, putative 0.1235 0.0765 0.209
Mycobacterium tuberculosis Probable cytochrome P450 130 Cyp130 0.0067 0.0021 0.0113
Mycobacterium ulcerans cytochrome P450 189A7 Cyp189A7 0.0067 0.0021 0.0098
Echinococcus multilocularis neuropeptide receptor A26 0.0937 0.0576 0.0576
Brugia malayi hypothetical protein 0.021 0.0113 0.0415
Trichomonas vaginalis PIKK family atypical protein kinase 0.1235 0.0765 0.7806
Leishmania major target of rapamycin kinase (TOR) kinase 3 0.128 0.0794 0.2168
Entamoeba histolytica fructose-1,6-bisphosphate aldolase, putative 0.0302 0.0171 0.2099
Echinococcus granulosus potassium:sodium hyperpolarization activated 0.0478 0.0283 0.0283
Trichomonas vaginalis calcium/calmodulin-dependent 3,5-cyclic nucleotide phosphodiesterase, putative 0.0479 0.0283 0.2852
Leishmania major hypothetical protein, conserved 0.0467 0.0276 0.0744
Entamoeba histolytica phosphatidylinositol 4-kinase, putative 0.0374 0.0217 0.267
Trichomonas vaginalis D-aminoacylase, putative 0.0108 0.0048 0.043
Echinococcus multilocularis short transient receptor potential channel 6 0.0467 0.0276 0.0276
Loa Loa (eye worm) hypothetical protein 0.0467 0.0276 0.1058
Schistosoma mansoni transient receptor potential channel 4 0.0467 0.0276 0.282
Schistosoma mansoni high-affinity cgmp-specific 35-cyclic phosphodiesterase 0.0133 0.0063 0.0648
Trypanosoma brucei target of rapamycin kinase 3, putative 0.128 0.0794 0.8098
Schistosoma mansoni high voltage-activated calcium channel Cav2A 0.0467 0.0276 0.282
Leishmania major 4-coumarate:coa ligase-like protein 0.0051 0.0011 0.0014
Loa Loa (eye worm) ryanodine receptor 0.0467 0.0276 0.1058
Loa Loa (eye worm) hypothetical protein 0.0133 0.0063 0.024
Echinococcus granulosus voltage gated potassium channel 0.0467 0.0276 0.0276
Onchocerca volvulus Transient receptor potential cation channel trpm homolog 0.0467 0.0276 1
Trichomonas vaginalis cGMP-inhibited 3,5-cyclic phosphodiesterase, putative 0.0133 0.0063 0.0592
Schistosoma mansoni voltage-gated potassium channel 0.0549 0.0328 0.3351
Trichomonas vaginalis calcium/calmodulin-dependent 3,5-cyclic nucleotide phosphodiesterase, putative 0.0133 0.0063 0.0592
Entamoeba histolytica phosphatidylinositol 3-kinase, putative 0.0972 0.0597 0.7403
Echinococcus granulosus melanoma receptor tyrosine protein kinase 0.0709 0.043 0.043
Loa Loa (eye worm) cytochrome P450 family protein 0.0087 0.0034 0.0128
Echinococcus multilocularis Niemann Pick C1 protein 0.0109 0.0048 0.0048
Leishmania major phosphatidylinositol kinase related protein, putative 0.0295 0.0167 0.0443
Brugia malayi Ulp1 protease family, C-terminal catalytic domain containing protein 0.0043 0.0006 0.0018
Mycobacterium ulcerans monoamine oxidase 0.021 0.0113 0.0585
Brugia malayi Phosphatidylinositol 3- and 4-kinase family protein 0.0723 0.0439 0.1632
Schistosoma mansoni calcium/calmodulin-dependent 35-cyclic nucleotide phosphodiesterase 0.0133 0.0063 0.0648
Echinococcus granulosus potassium large conductance calcium activated 0.0467 0.0276 0.0276
Trichomonas vaginalis cone cGMP-specific 3,5-cyclic phosphodiesterase, putative 0.0479 0.0283 0.2852
Trichomonas vaginalis CMGC family protein kinase 0.1571 0.0979 1
Trichomonas vaginalis fructose-bisphosphate aldolase, putative 0.0302 0.0171 0.1698
Loa Loa (eye worm) phosphatidylinositol 3 0.0264 0.0147 0.056
Loa Loa (eye worm) hypothetical protein 0.0467 0.0276 0.1058
Echinococcus granulosus serine protein kinase ATM 0.0742 0.0451 0.0451
Mycobacterium leprae conserved hypothetical protein 0.0345 0.0199 1
Trichomonas vaginalis cyclic nucleotide phosphodiesterase, putative 0.0479 0.0283 0.2852
Brugia malayi olfactory channel protein osm-9 0.0467 0.0276 0.1024
Entamoeba histolytica protein kinase rad3, putative 0.0711 0.0431 0.5336
Onchocerca volvulus 0.0051 0.0011 0.0187
Leishmania major mitogen activated protein kinase, putative,map kinase, putative 0.1571 0.0979 0.2677
Mycobacterium ulcerans cytochrome P450 108B4 Cyp108B4 0.0067 0.0021 0.0098
Mycobacterium tuberculosis Probable cytochrome P450 125 Cyp125 0.0067 0.0021 0.0113
Trichomonas vaginalis esterase, putative 0.0108 0.0048 0.043
Trichomonas vaginalis conserved hypothetical protein 0.0047 0.0008 0.0026
Mycobacterium ulcerans acyl-CoA synthetase 0.0051 0.0011 0.0044
Echinococcus granulosus Protein patched homolog 1 0.0047 0.0008 0.0008
Schistosoma mansoni phosphatidylinositol 3-and 4-kinase 0.1344 0.0834 0.8524
Trypanosoma cruzi mitogen-activated protein kinase 11, putative 0.1571 0.0979 0.2807
Trypanosoma brucei phosphatidylinositol 3-kinase, putative 0.1235 0.0765 0.7806
Schistosoma mansoni camp-specific 35-cyclic phosphodiesterase 0.0133 0.0063 0.0648
Trichomonas vaginalis PIKK family atypical protein kinase 0.128 0.0794 0.8097
Loa Loa (eye worm) hypothetical protein 0.0133 0.0063 0.024
Mycobacterium ulcerans cytochrome P450 144A4 Cyp144A4 0.0067 0.0021 0.0098
Mycobacterium tuberculosis Probable flavin-containing monoamine oxidase AofH (amine oxidase) (MAO) 0.2776 0.1747 1
Echinococcus multilocularis transient receptor potential cation channel 0.0467 0.0276 0.0276
Trichomonas vaginalis high-affinity cGMP-specific 3,5-cyclic phosphodiesterase, putative 0.0479 0.0283 0.2852
Trypanosoma cruzi cAMP specific phosphodiesterase, putative 0.0479 0.0283 0.0801
Echinococcus multilocularis sentrin specific protease 8 0.0102 0.0044 0.0044
Echinococcus multilocularis transient receptor potential cation channel 0.0467 0.0276 0.0276
Schistosoma mansoni hypothetical protein 0.0048 0.0009 0.0092
Trypanosoma cruzi phosphatidylinositol 3-kinase 2, putative 0.111 0.0685 0.196
Mycobacterium tuberculosis Probable cytochrome P450 137 Cyp137 0.0067 0.0021 0.0113
Leishmania major hypothetical protein, conserved 0.0133 0.0063 0.0158
Trichomonas vaginalis PIKK family atypical protein kinase 0.1275 0.079 0.8065
Mycobacterium tuberculosis Probable cytochrome P450 143 Cyp143 0.0067 0.0021 0.0113
Echinococcus granulosus cyclic nucleotide gated cation channel 0.0478 0.0283 0.0283
Echinococcus granulosus calcium:calmodulin dependent 3'5' cyclic 0.0133 0.0063 0.0063
Loa Loa (eye worm) hypothetical protein 0.0467 0.0276 0.1058
Mycobacterium ulcerans cytochrome P450 51B1 Cyp51B1 0.0067 0.0021 0.0098
Entamoeba histolytica phosphatidylinositol-4,5-bisphosphate 3-kinase, putative 0.0374 0.0217 0.267
Trypanosoma brucei phosphatidylinositol 3-kinase, putative 0.0512 0.0305 0.3071
Loa Loa (eye worm) hypothetical protein 0.0467 0.0276 0.1058
Echinococcus granulosus Potassium voltage gated channel protein Shaw 0.0467 0.0276 0.0276
Trichomonas vaginalis PIKK family atypical protein kinase 0.1255 0.0778 0.7936
Onchocerca volvulus 0.0108 0.0048 0.1547
Echinococcus multilocularis phosphatidylinositol 4,5 bisphosphate 3 kinase 0.1481 0.0922 0.0922
Schistosoma mansoni transient receptor potential cation channel subfamily m member 0.0467 0.0276 0.282
Brugia malayi beta-lactamase family protein 0.0108 0.0048 0.0174
Trichomonas vaginalis cAMP-specific 3,5-cyclic phosphodiesterase, putative 0.0479 0.0283 0.2852
Echinococcus granulosus neuropeptide receptor A26 0.0937 0.0576 0.0576
Brugia malayi FAT domain containing protein 0.0524 0.0313 0.1161
Trichomonas vaginalis calcium/calmodulin-dependent 3,5-cyclic nucleotide phosphodiesterase, putative 0.0479 0.0283 0.2852
Schistosoma mansoni phosphatidylinositol-45-bisphosphate 3-kinase catalytic subunit alpha PI3K 0.1481 0.0922 0.9417
Schistosoma mansoni hypothetical protein 0.0264 0.0147 0.1498
Schistosoma mansoni phosphatidylinositol 4-kinase 0.0264 0.0147 0.1498
Mycobacterium ulcerans acyl-CoA synthetase 0.0051 0.0011 0.0044
Mycobacterium tuberculosis Conserved hypothetical protein 0.0264 0.0147 0.0832
Giardia lamblia hypothetical protein 0.0133 0.0063 0.0592
Trichomonas vaginalis PIKK family atypical protein kinase 0.075 0.0456 0.4631
Loa Loa (eye worm) hypothetical protein 0.0043 0.0006 0.0019
Echinococcus multilocularis 0.0067 0.0021 0.0021
Brugia malayi Phosphatidylinositol 3- and 4-kinase family protein 0.0264 0.0147 0.0542
Mycobacterium tuberculosis Conserved protein 0.0108 0.0048 0.0265
Trypanosoma brucei Phosphatidylinositol 3-kinase tor1 0.13 0.0806 0.8227
Trichomonas vaginalis cGMP-inhibited 3,5-cyclic phosphodiesterase, putative 0.0479 0.0283 0.2852
Loa Loa (eye worm) hypothetical protein 0.0467 0.0276 0.1058
Mycobacterium tuberculosis Two component sensor histidine kinase DosT 0.0345 0.0199 0.1129
Echinococcus granulosus FKBP12 rapamycin complex associated protein 0.13 0.0806 0.0806
Toxoplasma gondii 3'5'-cyclic nucleotide phosphodiesterase domain-containing protein 0.0133 0.0063 0.0592
Schistosoma mansoni voltage-gated ion channel 0.0467 0.0276 0.282
Echinococcus granulosus voltage gated hydrogen channel 1 0.0467 0.0276 0.0276
Giardia lamblia Hypothetical protein 0.0264 0.0147 0.1447
Schistosoma mansoni tyrosine kinase 0.0702 0.0426 0.4347
Echinococcus multilocularis high affinity cAMP specific 3',5' cyclic 0.0133 0.0063 0.0063
Mycobacterium tuberculosis Probable cytochrome P450 136 Cyp136 0.0067 0.0021 0.0113
Giardia lamblia Encystation-specific protease 0.0085 0.0033 0.0278
Toxoplasma gondii non-specific serine/threonine protein kinase 0.0788 0.0481 0.488
Trichomonas vaginalis calcium/calmodulin-dependent 3,5-cyclic nucleotide phosphodiesterase, putative 0.0479 0.0283 0.2852
Mycobacterium tuberculosis Probable chain -fatty-acid-CoA ligase FadD13 (fatty-acyl-CoA synthetase) 0.0051 0.0011 0.0054
Echinococcus multilocularis potassium large conductance calcium activated 0.0467 0.0276 0.0276
Echinococcus granulosus phosphatidylinositol 3 kinase catalytic subunit 0.0374 0.0217 0.0217
Echinococcus multilocularis potassium:sodium hyperpolarization activated 0.0478 0.0283 0.0283
Leishmania major cAMP phosphodiesterase A, putative;with=GeneDB:LinJ18_V3.1100 0.0133 0.0063 0.0158
Trypanosoma brucei cAMP-specific phosphodiesterase 0.0479 0.0283 0.2852
Echinococcus multilocularis potassium voltage gated channel protein 0.0467 0.0276 0.0276
Trypanosoma cruzi hypothetical protein, conserved 0.0108 0.0048 0.0121
Brugia malayi cation channel family protein 0.0467 0.0276 0.1024
Echinococcus multilocularis PIK kinase, FAT and Armadillo domain containing protein 0.0524 0.0313 0.0313
Echinococcus granulosus p2X purinoceptor 4 0.0076 0.0027 0.0027
Trypanosoma cruzi Voltage-dependent calcium channel subunit, putative 0.0467 0.0276 0.078
Loa Loa (eye worm) hypothetical protein 0.0051 0.0011 0.0038
Trichomonas vaginalis PIKK family atypical protein kinase 0.1275 0.079 0.8065
Echinococcus multilocularis Ankyrin 0.0094 0.0039 0.0039
Echinococcus multilocularis expressed conserved protein 0.0102 0.0044 0.0044
Giardia lamblia GTOR 0.13 0.0806 0.8227
Schistosoma mansoni P2X receptor subunit 0.0076 0.0027 0.0277
Trichomonas vaginalis PIKK family atypical protein kinase 0.128 0.0794 0.8097
Plasmodium falciparum dipeptidyl aminopeptidase 2 0.0217 0.0117 0.5332
Entamoeba histolytica acyl-coA synthetase, putative 0.0051 0.0011 0.0107
Brugia malayi Voltage-gated potassium channel, Shab-family (KCNB, Kv2-like) alpha-subunit 0.0467 0.0276 0.1024
Echinococcus multilocularis cAMP and cAMP inhibited cGMP 3',5' cyclic 0.425 0.2685 0.2685
Echinococcus granulosus expressed conserved protein 0.0102 0.0044 0.0044
Schistosoma mansoni dipeptidyl-peptidase I (C01 family) 0.0217 0.0117 0.1195
Plasmodium vivax hypothetical protein, conserved 0.0264 0.0147 0.6719
Mycobacterium tuberculosis Fatty-acid-AMP ligase FadD30 (fatty-acid-AMP synthetase) (fatty-acid-AMP synthase) 0.0038 0.0003 0.0008
Toxoplasma gondii hypothetical protein 0.0345 0.0199 0.198
Schistosoma mansoni inositol 145-trisphosphate receptor 0.0467 0.0276 0.282
Trichomonas vaginalis PIKK family atypical protein kinase 0.0264 0.0147 0.1447
Echinococcus granulosus voltage gated potassium channel 0.0485 0.0287 0.0287
Echinococcus multilocularis voltage dependent calcium channel type d subunit 0.0467 0.0276 0.0276
Loa Loa (eye worm) hypothetical protein 0.0108 0.0048 0.0179
Brugia malayi MAP kinase sur-1 0.1571 0.0979 0.3642
Loa Loa (eye worm) hypothetical protein 0.0264 0.0147 0.056
Trypanosoma cruzi cytochrome p450-like protein, putative 0.0067 0.0021 0.0044
Brugia malayi Transient-receptor-potential like protein 0.0467 0.0276 0.1024
Schistosoma mansoni camp-specific 35-cyclic phosphodiesterase 0.0133 0.0063 0.0648
Echinococcus granulosus sodium channel protein 0.3467 0.2186 0.2186
Plasmodium falciparum cGMP-specific phosphodiesterase 0.0133 0.0063 0.2834
Mycobacterium ulcerans lipase LipD 0.0108 0.0048 0.0239
Trypanosoma brucei cAMP-specific phosphodiesterase 0.0479 0.0283 0.2852
Toxoplasma gondii 3'5'-cyclic nucleotide phosphodiesterase domain-containing protein 0.0133 0.0063 0.0592
Trichomonas vaginalis phosphatidylinositol kinase, putative 0.111 0.0685 0.6983
Trichomonas vaginalis high-affinity cGMP-specific 3,5-cyclic phosphodiesterase, putative 0.0133 0.0063 0.0592
Trichomonas vaginalis conserved hypothetical protein 0.0447 0.0263 0.2646
Echinococcus granulosus sentrin specific protease 1 0.0043 0.0006 0.0006
Trichomonas vaginalis phosphatidylinositol 3-kinase catalytic subunit gamma, putative 0.111 0.0685 0.6983
Mycobacterium ulcerans cytochrome P450 191A3 Cyp191A3 0.0067 0.0021 0.0098
Schistosoma mansoni transient receptor potential cation channel subfamily m member 0.0467 0.0276 0.282
Mycobacterium tuberculosis Probable cytochrome P450 123 Cyp123 0.0067 0.0021 0.0113
Brugia malayi cytochrome P450 0.0067 0.0021 0.0075
Trichomonas vaginalis conserved hypothetical protein 0.0479 0.0283 0.2852
Echinococcus multilocularis voltage dependent calcium channel type d subunit 0.0467 0.0276 0.0276
Plasmodium vivax 3',5'-cyclic nucleotide phosphodiesterase, putative 0.0133 0.0063 0.2834
Trypanosoma cruzi phosphatidylinositol kinase, putative 0.0264 0.0147 0.0406
Echinococcus multilocularis transfer RNA-Gly 0.0467 0.0276 0.0276
Loa Loa (eye worm) phosphatidylinositol kinase 0.0264 0.0147 0.056
Brugia malayi MH2 domain containing protein 0.0123 0.0057 0.0209
Trypanosoma brucei cAMP-specific phosphodiesterase, putative 0.0133 0.0063 0.0592
Loa Loa (eye worm) voltage and ligand gated potassium channel 0.0541 0.0323 0.124
Echinococcus multilocularis potassium voltage gated channel subfamily H 0.0485 0.0287 0.0287
Plasmodium vivax phosphatidylinositol 3-kinase, putative 0.0374 0.0217 1
Trypanosoma cruzi cAMP phosphodiesterase A, putative 0.0133 0.0063 0.0166
Echinococcus multilocularis voltage dependent L type calcium channel subunit 0.0467 0.0276 0.0276
Plasmodium vivax dipeptidyl aminopeptidase 3, putative 0.0085 0.0033 0.1408
Trichomonas vaginalis Sentrin-specific protease, putative 0.0102 0.0044 0.0387
Trypanosoma cruzi hypothetical protein, conserved 0.0133 0.0063 0.0166
Schistosoma mansoni hypothetical protein 0.0467 0.0276 0.282
Trichomonas vaginalis PIKK family atypical protein kinase 0.1255 0.0778 0.7936
Loa Loa (eye worm) hypothetical protein 0.021 0.0113 0.0429
Mycobacterium ulcerans putative regulatory protein 0.0345 0.0199 0.1042
Trichomonas vaginalis fructose-bisphosphate aldolase, putative 0.0302 0.0171 0.1698
Loa Loa (eye worm) hypothetical protein 0.0386 0.0225 0.086
Schistosoma mansoni P2X receptor subunit 0.0076 0.0027 0.0277
Schistosoma mansoni voltage-gated potassium channel 0.0485 0.0287 0.2936
Leishmania major cytochrome p450-like protein 0.0067 0.0021 0.0042
Trypanosoma brucei phosphatidylinositol 3-kinase catalytic subunit, putative 0.0264 0.0147 0.1447
Schistosoma mansoni calcium-activated potassium channel 0.0467 0.0276 0.282
Trichomonas vaginalis PIKK family atypical protein kinase 0.1235 0.0765 0.7806
Toxoplasma gondii histone lysine-specific demethylase 0.021 0.0113 0.1097
Trypanosoma cruzi mitogen activated protein kinase 4, putative 0.1571 0.0979 0.2807
Loa Loa (eye worm) transcription factor SMAD2 0.0123 0.0057 0.0216
Mycobacterium tuberculosis Possible conserved lipoprotein LpqK 0.0108 0.0048 0.0265
Brugia malayi Voltage-gated potassium channel, Shaw-family (KCNC, Kv3-like) alpha-subunit. C. elegans egl-36 ortholog 0.0467 0.0276 0.1024
Schistosoma mansoni tyrosine kinase 0.0422 0.0247 0.2526
Plasmodium falciparum dipeptidyl aminopeptidase 3 0.0085 0.0033 0.1408
Echinococcus multilocularis shaker cognate 0.0467 0.0276 0.0276
Entamoeba histolytica phosphatidylinositol 3-kinase, putative 0.0512 0.0305 0.3761
Trypanosoma cruzi phosphatidylinositol 3-related kinase, putative 0.1344 0.0834 0.239
Brugia malayi Ulp1 protease family, C-terminal catalytic domain containing protein 0.0043 0.0006 0.0018
Echinococcus multilocularis voltage dependent calcium channel 0.0467 0.0276 0.0276
Trichomonas vaginalis cGMP-dependent 3,5-cyclic phosphodiesterase, putative 0.0479 0.0283 0.2852
Trypanosoma cruzi cAMP-specific phosphodiesterase, putative 0.0133 0.0063 0.0166
Loa Loa (eye worm) beta-lactamase 0.0108 0.0048 0.0179
Echinococcus granulosus phosphatidylinositol 3 and 4 kinase 0.1344 0.0834 0.0834
Chlamydia trachomatis deubiquitinase/deneddylase Dub2 0.0043 0.0006 0.0284
Leishmania major target of rapamycin (TOR) kinase 1, putative 0.13 0.0806 0.2203
Trichomonas vaginalis PIKK family atypical protein kinase 0.1275 0.079 0.8065
Onchocerca volvulus Transient receptor potential cation channel trpm homolog 0.0467 0.0276 1
Brugia malayi Cytochrome P450 family protein 0.0234 0.0127 0.0471
Trichomonas vaginalis calcium/calmodulin-dependent 3',5'-cyclic nucleotide phosphodiesterase, putative 0.0133 0.0063 0.0592
Trypanosoma cruzi phosphatidylinositol 3-kinase, putative 0.0248 0.0137 0.0377
Trichomonas vaginalis penicillin-binding protein, putative 0.0108 0.0048 0.043
Brugia malayi phosphoinositide 3'-hydroxykinase p110-alpha subunit, putative 0.0371 0.0215 0.0797
Brugia malayi beta-lactamase family protein 0.0108 0.0048 0.0174
Onchocerca volvulus 0.021 0.0113 0.3949
Mycobacterium ulcerans cytochrome P450 123A3 Cyp123A3 0.0067 0.0021 0.0098
Schistosoma mansoni tyrosine kinase 0.0702 0.0426 0.4347
Trichomonas vaginalis cAMP-specific phosphodiesterase, putative 0.0133 0.0063 0.0592
Echinococcus granulosus tumor necrosis factor receptor superfamily 0.0144 0.007 0.007
Loa Loa (eye worm) hypothetical protein 0.0467 0.0276 0.1058
Mycobacterium tuberculosis Probable epoxide hydrolase EphA (epoxide hydratase) (arene-oxide hydratase) 0.016 0.0081 0.0453
Trichomonas vaginalis Clan CE, family C48, Ulp1-like cysteine peptidase 0.0102 0.0044 0.0387
Trichomonas vaginalis PIKK family atypical protein kinase 0.128 0.0794 0.8097
Mycobacterium ulcerans cytochrome P450 142A3 Cyp142A3 0.0067 0.0021 0.0098
Onchocerca volvulus Netrin receptor homolog 0.0094 0.0039 0.121
Schistosoma mansoni hypothetical protein 0.0067 0.0021 0.0216
Schistosoma mansoni cgmp-dependent 35-cyclic phosphodiesterase 0.0479 0.0283 0.2895
Loa Loa (eye worm) CYP4Cod1 0.0087 0.0034 0.0128
Brugia malayi Voltage-gated calcium channel, alpha subunit 0.0467 0.0276 0.1024
Echinococcus multilocularis protoporphyrinogen oxidase 0.021 0.0113 0.0113
Mycobacterium ulcerans cytochrome P450 126A3 Cyp126A3 0.0067 0.0021 0.0098
Toxoplasma gondii phosphatidylinositol 3- and 4-kinase 0.0374 0.0217 0.2169
Echinococcus granulosus p2X purinoceptor 4 0.0076 0.0027 0.0027
Echinococcus multilocularis transient receptor potential cation channel 0.0467 0.0276 0.0276
Schistosoma mansoni Protoporphyrinogen oxidase chloroplast/mitochondrial precursor 0.021 0.0113 0.115
Trichomonas vaginalis calcium/calmodulin-dependent 3,5-cyclic nucleotide phosphodiesterase, putative 0.0479 0.0283 0.2852
Schistosoma mansoni two-pore calcium channel 0.0467 0.0276 0.282
Echinococcus granulosus ryanodine receptor 44f 0.0467 0.0276 0.0276
Trichomonas vaginalis phosphatidylinositol 3-kinase class, putative 0.0374 0.0217 0.2169
Echinococcus granulosus cyclic nucleotide gated cation channel 0.0478 0.0283 0.0283
Brugia malayi SWIRM domain containing protein 0.021 0.0113 0.0415
Loa Loa (eye worm) Ulp1 protease 0.0043 0.0006 0.0019
Echinococcus granulosus TRP transient receptor potential channel 0.0467 0.0276 0.0276
Leishmania major phosphatidylinositol 3-kinase, putative 0.0374 0.0217 0.0581
Toxoplasma gondii 3'5'-cyclic nucleotide phosphodiesterase domain-containing protein 0.0133 0.0063 0.0592
Leishmania major UDP-galactopyranose mutase 0.021 0.0113 0.0294
Echinococcus multilocularis insulin receptor 0.0422 0.0247 0.0247
Schistosoma mansoni voltage-gated potassium channel 0.0467 0.0276 0.282
Plasmodium vivax protoporphyrinogen oxidase, putative 0.021 0.0113 0.5127
Echinococcus granulosus cyclic nucleotide gated cation channel alpha 3 0.0478 0.0283 0.0283
Loa Loa (eye worm) hypothetical protein 0.0711 0.0431 0.1655
Trichomonas vaginalis cGMP-specific 3,5-cyclic phosphodiesterase, putative 0.0479 0.0283 0.2852
Plasmodium falciparum phosphatidylinositol 3- and 4-kinase, putative 0.0264 0.0147 0.6719
Trichomonas vaginalis rod cGMP-specific 3,5-cyclic phosphodiesterase, putative 0.0479 0.0283 0.2852
Echinococcus multilocularis tumor necrosis factor receptor superfamily 0.0144 0.007 0.007
Echinococcus granulosus serine:threonine protein kinase SMG1 0.0711 0.0431 0.0431
Mycobacterium ulcerans cytochrome P450 140A5 Cyp140A5 0.0067 0.0021 0.0098
Loa Loa (eye worm) voltage-gated calcium channel 0.0467 0.0276 0.1058
Trichomonas vaginalis voltage and ligand gated potassium channel, putative 0.0074 0.0026 0.0205
Toxoplasma gondii hypothetical protein 0.0345 0.0199 0.198
Echinococcus multilocularis cyclic nucleotide gated cation channel 0.0478 0.0283 0.0283
Loa Loa (eye worm) hypothetical protein 0.0467 0.0276 0.1058
Schistosoma mansoni family C48 unassigned peptidase (C48 family) 0.0043 0.0006 0.006
Brugia malayi Voltage-gated potassium channel, Shaw-family (KCNC, Kv3-like) alpha-subunit 0.0467 0.0276 0.1024
Mycobacterium ulcerans protoporphyrinogen oxidase 0.021 0.0113 0.0585
Mycobacterium tuberculosis Probable cytochrome P450 138 Cyp138 0.0067 0.0021 0.0113
Echinococcus multilocularis calcium:calmodulin dependent 3',5' cyclic 0.0133 0.0063 0.0063
Loa Loa (eye worm) hypothetical protein 0.4117 0.2601 1
Schistosoma mansoni tyrosine kinase 0.0422 0.0247 0.2526
Trichomonas vaginalis conserved hypothetical protein 0.0788 0.0481 0.488
Echinococcus multilocularis beta LACTamase domain containing family member 0.0108 0.0048 0.0048
Trichomonas vaginalis phosphatidylinositol 3-kinase class, putative 0.0898 0.0551 0.56
Schistosoma mansoni hyperpolarization activated cyclic nucleotide-gated potassium channel 0.0478 0.0283 0.2889
Toxoplasma gondii hypothetical protein 0.0467 0.0276 0.2777
Trypanosoma cruzi phosphatidylinositol kinase related protein, putative 0.0295 0.0167 0.0464
Echinococcus multilocularis mitogen activated protein kinase 3 0.1571 0.0979 0.0979
Entamoeba histolytica Phosphatidylinositol 3- and 4-kinase family 0.0734 0.0446 0.5519
Schistosoma mansoni retinoblastoma-binding protein 4 (rbbp4) 0.0094 0.0039 0.0394
Trypanosoma cruzi hypothetical protein, conserved 0.0133 0.0063 0.0166
Leishmania major lanosterol 14-alpha-demethylase, putative 0.0067 0.0021 0.0042
Plasmodium vivax lysine-specific histone demethylase 1, putative 0.021 0.0113 0.5127
Mycobacterium ulcerans cytochrome P450 187A5 Cyp187A5 0.0067 0.0021 0.0098
Onchocerca volvulus 0.0055 0.0013 0.028
Mycobacterium ulcerans cytochrome P450 187A4 Cyp187A4 0.0067 0.0021 0.0098
Schistosoma mansoni hyperpolarization activated cyclic nucleotide-gated potassium channel 0.0467 0.0276 0.282
Trypanosoma cruzi phosphatidylinositol 4-kinase alpha, putative 0.0374 0.0217 0.0609
Mycobacterium tuberculosis Probable esterase LipL 0.0108 0.0048 0.0265
Mycobacterium ulcerans two component sensor histidine kinase DevS 0.0345 0.0199 0.1042
Echinococcus multilocularis TNFR CD27 30 40 95 cysteine rich region 0.0144 0.007 0.007
Trichomonas vaginalis PIKK family atypical protein kinase 0.075 0.0456 0.4631
Onchocerca volvulus 0.0048 0.0009 0.0117
Echinococcus granulosus sentrin specific protease 8 0.0102 0.0044 0.0044
Schistosoma mansoni cyclic-nucleotide-gated cation channel 0.0467 0.0276 0.282
Schistosoma mansoni cytochrome P450 0.0067 0.0021 0.0216
Giardia lamblia Phosphatidylinositol 4-kinase 0.0264 0.0147 0.1447
Leishmania major target of rapamycin (TOR) kinase 2, putative 0.13 0.0806 0.2203
Brugia malayi Probable 3',5'-cyclic phosphodiesterase C32E12.2, putative 0.425 0.2685 1
Mycobacterium leprae putative cytochrome p450 0.0067 0.0021 0.0543
Loa Loa (eye worm) hypothetical protein 0.0038 0.0003 0.0007
Schistosoma mansoni voltage-gated potassium channel 0.0467 0.0276 0.282
Schistosoma mansoni hypothetical protein 0.0045 0.0007 0.0075
Plasmodium vivax sentrin-specific protease 1, putative 0.0043 0.0006 0.0146
Loa Loa (eye worm) hypothetical protein 0.0531 0.0317 0.1214
Chlamydia trachomatis deubiquitinase/deneddylase Dub1 0.0043 0.0006 0.0284
Plasmodium vivax phosphatidylinositol 3- and 4-kinase, putative 0.0264 0.0147 0.6719
Leishmania major phosphatidylinositol 4-kinase, putative 0.0264 0.0147 0.0387
Loa Loa (eye worm) hypothetical protein 0.0051 0.0011 0.0038
Entamoeba histolytica hypothetical protein 0.0972 0.0597 0.7403
Trypanosoma brucei phosphatidylinositol 4-kinase, putative 0.0264 0.0147 0.1447
Toxoplasma gondii histone lysine-specific demethylase LSD1/BHC110/KDMA1A 0.0212 0.0114 0.1109
Brugia malayi Phosphatidylinositol 3- and 4-kinase family protein 0.0512 0.0305 0.1131
Trypanosoma brucei protein kinase, putative 0.1571 0.0979 1
Schistosoma mansoni hypothetical protein 0.0524 0.0313 0.3194
Schistosoma mansoni netrin receptor unc5 0.0094 0.0039 0.0394
Echinococcus granulosus sodium leak channel non selective protein 0.0467 0.0276 0.0276
Trypanosoma cruzi phosphatidylinositol kinase related protein, putative 0.0478 0.0283 0.0801
Mycobacterium tuberculosis Probable cytochrome P450 monooxygenase 142 Cyp142 0.0067 0.0021 0.0113
Echinococcus granulosus transient receptor potential cation channel 0.0467 0.0276 0.0276
Loa Loa (eye worm) phosphatidylinositol 3 0.0264 0.0147 0.056
Brugia malayi Cytochrome P450 family protein 0.0087 0.0034 0.0124
Loa Loa (eye worm) hypothetical protein 0.0467 0.0276 0.1058
Brugia malayi Ulp1 protease family, C-terminal catalytic domain containing protein 0.0043 0.0006 0.0018
Echinococcus granulosus dual 3'5' cyclic AMP and GMP phosphodiesterase 0.0479 0.0283 0.0283
Schistosoma mansoni hypothetical protein 0.0094 0.0039 0.0394
Mycobacterium ulcerans cytochrome P450 185A4 Cyp185A4 0.0087 0.0034 0.0168
Brugia malayi Phosphatidylinositol 3- and 4-kinase family protein 0.0264 0.0147 0.0542
Echinococcus multilocularis atpase aaa+ type core atpase aaa type core 0.1736 0.1084 0.1084
Loa Loa (eye worm) hypothetical protein 0.0467 0.0276 0.1058
Trypanosoma brucei Voltage-dependent calcium channel subunit, putative 0.0467 0.0276 0.2777
Plasmodium falciparum GAF domain-related protein, putative 0.0345 0.0199 0.914
Brugia malayi Uncoordinated protein 44 0.0094 0.0039 0.014
Loa Loa (eye worm) hypothetical protein 0.021 0.0113 0.0429
Brugia malayi 3'5'-cyclic nucleotide phosphodiesterase family protein 0.0133 0.0063 0.0233
Leishmania major 4-coumarate:coa ligase-like protein 0.0051 0.0011 0.0014
Trichomonas vaginalis CMGC family protein kinase 0.1571 0.0979 1
Schistosoma mansoni family C48 unassigned peptidase (C48 family) 0.0043 0.0006 0.006
Plasmodium falciparum 3',5'-cyclic nucleotide phosphodiesterase, putative 0.0133 0.0063 0.2834
Echinococcus multilocularis DNA dependent protein kinase catalytic subunit 1.5736 1 1
Echinococcus multilocularis voltage dependent calcium channel 0.0467 0.0276 0.0276
Trichomonas vaginalis high-affinity cGMP-specific 3,5-cyclic phosphodiesterase, putative 0.0479 0.0283 0.2852
Brugia malayi 3'5'-cyclic nucleotide phosphodiesterase family protein 0.0479 0.0283 0.1052
Echinococcus multilocularis cAMP specific 3',5' cyclic phosphodiesterase 0.0133 0.0063 0.0063
Trichomonas vaginalis PIKK family atypical protein kinase 0.0264 0.0147 0.1447
Brugia malayi ion channel NompC 0.0467 0.0276 0.1024
Schistosoma mansoni cellular tumor antigen P53 0.0055 0.0013 0.0137
Echinococcus multilocularis voltage dependent L type calcium channel subunit 0.0467 0.0276 0.0276
Schistosoma mansoni voltage-gated potassium channel 0.0467 0.0276 0.282
Loa Loa (eye worm) hypothetical protein 0.0109 0.0048 0.018
Toxoplasma gondii 3'5'-cyclic nucleotide phosphodiesterase domain-containing protein 0.0133 0.0063 0.0592
Echinococcus multilocularis neuropeptide s receptor 0.0937 0.0576 0.0576
Mycobacterium ulcerans fructose-bisphosphate aldolase 0.0148 0.0073 0.0372
Entamoeba histolytica Ulp1 protease family, C-terminal catalytic domain containing protein 0.0043 0.0006 0.0044
Leishmania major phosphatidylinositol kinase, putative 0.0264 0.0147 0.0387
Echinococcus multilocularis voltage gated hydrogen channel 1 0.0467 0.0276 0.0276
Mycobacterium tuberculosis Probable cytochrome P450 139 Cyp139 0.0067 0.0021 0.0113
Mycobacterium tuberculosis Probable fatty-acid-CoA ligase FadD2 (fatty-acid-CoA synthetase) (fatty-acid-CoA synthase) 0.0051 0.0011 0.0054
Schistosoma mansoni voltage-gated potassium channel 0.0467 0.0276 0.282
Trypanosoma cruzi cAMP specific phosphodiesterase, putative 0.0479 0.0283 0.0801
Trypanosoma cruzi cytochrome P450, putative 0.0087 0.0034 0.0082
Schistosoma mansoni cyclic-nucleotide-gated cation channel 0.0478 0.0283 0.2889
Mycobacterium ulcerans hypothetical protein 0.0051 0.0011 0.0044
Trypanosoma cruzi UDP-galactopyranose mutase 0.021 0.0113 0.0308
Mycobacterium tuberculosis Probable lipase LipD 0.0108 0.0048 0.0265
Brugia malayi beta-lactamase 0.0108 0.0048 0.0174
Trypanosoma cruzi hypothetical protein, conserved 0.0133 0.0063 0.0166
Echinococcus multilocularis epidermal growth factor receptor 0.0709 0.043 0.043

Activities

Activity type Activity value Assay description Source Reference
IC50 (functional) = 11.4 ug ml-1 Antiproliferative activity against human MCF7 cells after 48 hrs by MTT assay ChEMBL. 21109433
IC50 (functional) > 128 ug ml-1 Antifungal activity against Candida albicans SC5314 assessed as inhibition of biofilm formation by XTT assay ChEMBL. 26394911
IC50 (functional) > 128 ug ml-1 Antifungal activity against Candida albicans SC5314 assessed as inhibition of yeast cell to hyphae transition after 4 hrs by microscopic analysis ChEMBL. 26394911
IC50 (functional) = 4.7 uM Cytotoxicity against human K562 cells after 72 hrs by CCK8 assay ChEMBL. 26316467
IC50 (functional) = 47 uM Cytotoxicity against human MCF7 cells after 72 hrs by CCK8 assay ChEMBL. 26316467
Inhibition (binding) Inhibition of human recombinant COX-2 using arachidonic acid after 15 mins by fluorescence based assay ChEMBL. 26316467
Inhibition (binding) Inhibition of ovine COX-1 using arachidonic acid after 15 mins by fluorescence based assay ChEMBL. 26316467

Phenotypes

Whole-cell/tissue/organism interactions

Species name Source Reference Is orphan
Homo sapiens ChEMBL23 21109433

Many chemical entities in TDR Targets come from high-throughput screenings with whole cells or tissue samples, and not all assayed compounds have been tested against a single a single target protein, probably because they get ruled out during screening process. Even if these compounds may have not been of interest in the original screening, they may come as interesting leads for other screening assays. Furthermore, we may be able to propose drug-target associations using chemical similarities and network patterns.

Annotated phenotypes:

We have no manually annotated phenotypes for this drug. What does this mean? / Care to help?
In TDR Targets, information about phenotypes that are caused by drugs, or by genetic manipulation of cells (e.g. gene knockouts or knockdowns) is manually curated from the literature. These descriptions help to describe the potential of the target for drug development. If no information is available for this gene or if the information is incomplete, this may mean that i) the papers containing this information either appeared after the curation effort for this organism was carried out or they were inadvertently missed by curators; or that ii) the curation effort for this organism has not yet started.
 
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External resources for this compound

Bibliographic References

1 literature reference was collected for this gene.

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