Detailed information for compound 1497298

Basic information

Technical information
  • TDR Targets ID: 1497298
  • Name: [4-(benzoyl)phenyl]-[4-(4-hydroxyphenyl)piper azin-1-yl]methanone
  • MW: 386.443 | Formula: C24H22N2O3
  • H donors: 1 H acceptors: 3 LogP: 3.96 Rotable bonds: 5
    Rule of 5 violations (Lipinski): 1
  • SMILES: Oc1ccc(cc1)N1CCN(CC1)C(=O)c1ccc(cc1)C(=O)c1ccccc1
  • InChi: 1S/C24H22N2O3/c27-22-12-10-21(11-13-22)25-14-16-26(17-15-25)24(29)20-8-6-19(7-9-20)23(28)18-4-2-1-3-5-18/h1-13,27H,14-17H2
  • InChiKey: FVLJONVFCYWXAG-UHFFFAOYSA-N  


Substructure search Similarity search

Network

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Synonyms

  • [4-(4-hydroxyphenyl)-1-piperazinyl]-[4-(oxo-phenylmethyl)phenyl]methanone
  • [4-(4-hydroxyphenyl)piperazin-1-yl]-(4-phenylcarbonylphenyl)methanone
  • ZINC06786794
  • T5376402

Targets

Known targets for this compound

Species Target name Source Bibliographic reference
Homo sapiens glucagon-like peptide 1 receptor Starlite/ChEMBL No references
Homo sapiens lysine (K)-specific demethylase 4A Starlite/ChEMBL No references
Homo sapiens GNAS complex locus Starlite/ChEMBL No references

Predicted pathogen targets for this compound

By orthology
Species Potential target Known druggable target/s Ortholog Group
Candida albicans one of two closely related potential jumonji-like transcription factor genes similar to S. cerevisiae RPH1 (YER169W) damage-resp Get druggable targets OG5_127917 All targets in OG5_127917
Candida albicans one of two closely related potential jumonji-like transcription factor genes similar to S. cerevisiae RPH1 (YER169W) damage-resp Get druggable targets OG5_127917 All targets in OG5_127917
Echinococcus granulosus guanine nucleotide binding protein Gs subunit Get druggable targets OG5_131088 All targets in OG5_131088
Echinococcus multilocularis guanine nucleotide binding protein G(s) subunit Get druggable targets OG5_131088 All targets in OG5_131088
Echinococcus granulosus jumonji domain containing protein Get druggable targets OG5_127917 All targets in OG5_127917
Candida albicans one of two closely related potential jumonji-like transcription factor genes similar to S. cerevisiae RPH1 (YER169W) damage-resp Get druggable targets OG5_127917 All targets in OG5_127917
Schistosoma mansoni Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) Get druggable targets OG5_131088 All targets in OG5_131088
Echinococcus multilocularis jumonji domain containing protein Get druggable targets OG5_127917 All targets in OG5_127917
Schistosoma japonicum Probable JmjC domain-containing histone demethylation protein 3B, putative Get druggable targets OG5_127917 All targets in OG5_127917
Candida albicans one of two closely related potential jumonji-like transcription factor genes similar to S. cerevisiae RPH1 (YER169W) damage-resp Get druggable targets OG5_127917 All targets in OG5_127917
Echinococcus granulosus guanine nucleotide binding protein Gs subunit Get druggable targets OG5_131088 All targets in OG5_131088
Echinococcus multilocularis guanine nucleotide binding protein G(s) subunit Get druggable targets OG5_131088 All targets in OG5_131088
Loa Loa (eye worm) GTP-binding regulatory protein Gs alpha-S chain Get druggable targets OG5_131088 All targets in OG5_131088
Schistosoma mansoni jumonji domain containing protein Get druggable targets OG5_127917 All targets in OG5_127917
Loa Loa (eye worm) jmjC domain-containing protein Get druggable targets OG5_127917 All targets in OG5_127917
Schistosoma japonicum expressed protein Get druggable targets OG5_127917 All targets in OG5_127917
Schistosoma mansoni Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) Get druggable targets OG5_131088 All targets in OG5_131088
Plasmodium yoelii hypothetical protein Get druggable targets OG5_127917 All targets in OG5_127917
Schistosoma japonicum expressed protein Get druggable targets OG5_127917 All targets in OG5_127917
Loa Loa (eye worm) hypothetical protein Get druggable targets OG5_127917 All targets in OG5_127917
Brugia malayi jmjC domain containing protein Get druggable targets OG5_127917 All targets in OG5_127917
Echinococcus multilocularis Transcription factor, JmjC domain containing protein Get druggable targets OG5_127917 All targets in OG5_127917
Schistosoma mansoni Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) Get druggable targets OG5_131088 All targets in OG5_131088
Echinococcus granulosus Transcription factor JmjC domain containing protein Get druggable targets OG5_127917 All targets in OG5_127917
Schistosoma japonicum ko:K04632 guanine nucleotide binding protein (G protein), alpha stimulating, putative Get druggable targets OG5_131088 All targets in OG5_131088
Schistosoma japonicum JmjC domain-containing histone demethylation protein 3C, putative Get druggable targets OG5_127917 All targets in OG5_127917
Brugia malayi GTP-binding regulatory protein Gs alpha-S chain, putative Get druggable targets OG5_131088 All targets in OG5_131088
By sequence similarity to non orthologous known druggable targets
Species Potential target Known druggable target Length Alignment span Identity
Loa Loa (eye worm) pigment dispersing factor receptor c glucagon-like peptide 1 receptor 463 aa 388 aa 25.8 %
Schistosoma mansoni GTP-binding protein alpha subunit gna GNAS complex locus 394 aa 450 aa 28.7 %
Obtained from network model

Ranking Plot

Putative Targets List

Species Potential target Raw Global Species
Loa Loa (eye worm) F/Y-rich family protein 0.0024 0.0009 0.0011
Loa Loa (eye worm) hypothetical protein 0.0029 0.0028 0.0032
Schistosoma mansoni tyrosine kinase 0.0035 0.0053 0.0044
Trypanosoma cruzi cAMP specific phosphodiesterase, putative 0.0059 0.0147 0.052
Trichomonas vaginalis conserved hypothetical protein 0.0071 0.0194 0.0408
Plasmodium falciparum cysteine proteinase falcipain 1 0.0103 0.0318 0.2268
Echinococcus multilocularis cadherin EGF LAG seven pass G type receptor 0.0082 0.0237 0.0228
Trypanosoma cruzi trypanothione reductase, putative 0.0052 0.0119 0.0419
Giardia lamblia Cathepsin L-like protease 0.0051 0.0114 0.0495
Giardia lamblia Cathepsin L precursor 0.0051 0.0114 0.0495
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0157 0.053 0.5506
Entamoeba histolytica cysteine protease, putative 0.0103 0.0318 0.3517
Schistosoma mansoni nuclear hormone receptor nor-1/nor-2 0.0082 0.0235 0.0225
Trichomonas vaginalis calcium/calmodulin-dependent 3,5-cyclic nucleotide phosphodiesterase, putative 0.0059 0.0147 0.0309
Brugia malayi Papain family cysteine protease containing protein 0.0051 0.0114 0.0124
Brugia malayi hypothetical protein 0.0464 0.1732 0.1991
Trichomonas vaginalis bromodomain-containing protein, putative 0.006 0.015 0.0315
Trypanosoma cruzi ISWI complex protein 0.011 0.0345 0.1219
Entamoeba histolytica cysteine proteinase, putative 0.0103 0.0318 0.3517
Brugia malayi fibroinase precursor 0.0051 0.0114 0.0124
Schistosoma mansoni nephrin 0.0036 0.0057 0.0047
Trichomonas vaginalis chromobox protein, putative 0.0069 0.0187 0.0392
Schistosoma mansoni SmCL2-like peptidase (C01 family) 0.0103 0.0318 0.0309
Leishmania major cathepsin L-like protease 0.0111 0.0349 0.3616
Entamoeba histolytica cysteine protease, putative 0.0103 0.0318 0.3517
Echinococcus multilocularis fetal alzheimer antigen, falz 0.0172 0.0589 0.058
Schistosoma mansoni cell adhesion molecule 0.0038 0.0065 0.0055
Loa Loa (eye worm) hypothetical protein 0.0038 0.0065 0.0075
Trypanosoma cruzi cysteine peptidase (N-terminal), putative 0.0103 0.0318 0.1123
Brugia malayi nuclear receptor RXR 0.0043 0.0084 0.009
Loa Loa (eye worm) TK/KIN16 protein kinase 0.0483 0.1807 0.2084
Trichomonas vaginalis calcium/calmodulin-dependent 3,5-cyclic nucleotide phosphodiesterase, putative 0.0059 0.0147 0.0309
Echinococcus granulosus microtubule associated protein 2 0.1375 0.5299 0.5294
Echinococcus granulosus chromodomain helicase DNA binding protein 4 0.0035 0.0054 0.0044
Loa Loa (eye worm) hypothetical protein 0.0023 0.0006 0.0007
Brugia malayi nuclear receptor NHR-67 0.0038 0.0066 0.0069
Trypanosoma cruzi dihydrolipoamide dehydrogenase, putative 0.0052 0.0119 0.0419
Echinococcus multilocularis Transcription factor, JmjC domain containing protein 0.0292 0.1058 0.1049
Trichomonas vaginalis calcium/calmodulin-dependent 3,5-cyclic nucleotide phosphodiesterase, putative 0.0059 0.0147 0.0309
Loa Loa (eye worm) hypothetical protein 0.0026 0.0019 0.0022
Onchocerca volvulus 0.005 0.0111 0.0221
Schistosoma mansoni matrix metallopeptidase-7 (M10 family) 0.0035 0.0053 0.0043
Brugia malayi Hemopexin family protein 0.005 0.011 0.012
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0051 0.0114 0.0237
Trichomonas vaginalis conserved hypothetical protein 0.0024 0.0009 0.0017
Schistosoma mansoni histone-lysine n-methyltransferase setb1 0.0158 0.0536 0.0527
Brugia malayi tailless protein 0.0038 0.0066 0.0069
Brugia malayi nuclear hormone receptor 0.0082 0.0235 0.0263
Trichomonas vaginalis cAMP and cAMP-inhibited cGMP 3,5-cyclic phosphodiesterase, putative 0.004 0.0073 0.0152
Loa Loa (eye worm) hypothetical protein 0.0052 0.012 0.0138
Plasmodium vivax hypothetical protein, conserved 0.0089 0.0264 0.1871
Schistosoma mansoni cathepsin B-like peptidase (C01 family) 0.0745 0.2833 0.2826
Brugia malayi Calcitonin receptor-like protein seb-1 0.026 0.0932 0.1068
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0111 0.0349 0.0736
Mycobacterium tuberculosis Probable nitrite reductase [NAD(P)H] large subunit [FAD flavoprotein] NirB 0.0342 0.1253 0.5026
Brugia malayi F/Y-rich N-terminus family protein 0.0104 0.0322 0.0364
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0157 0.053 0.5506
Entamoeba histolytica cysteine proteinase 1, putative 0.0103 0.0318 0.3517
Entamoeba histolytica cysteine proteinase, putative 0.0103 0.0318 0.3517
Trichomonas vaginalis glucosylceramidase, putative 0.0524 0.1966 0.4154
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0157 0.053 0.5506
Loa Loa (eye worm) hypothetical protein 0.0051 0.0114 0.0131
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0111 0.0349 0.0736
Brugia malayi ecdysteroid receptor 0.0082 0.0235 0.0263
Plasmodium falciparum heat shock protein 90, putative 0.0372 0.1371 1
Entamoeba histolytica cysteine proteinase 2 0.0103 0.0318 0.3517
Brugia malayi Nuclear hormone receptor family member nhr-25 0.0082 0.0235 0.0263
Loa Loa (eye worm) hypothetical protein 0.0144 0.0481 0.0554
Brugia malayi hypothetical protein 0.0049 0.0106 0.0115
Trichomonas vaginalis glucosylceramidase, putative 0.0524 0.1966 0.4154
Entamoeba histolytica cysteine proteinase, putative 0.0059 0.0145 0.1562
Plasmodium vivax serine-repeat antigen 4 (SERA), putative 0.0051 0.0114 0.0765
Trichomonas vaginalis glucosylceramidase, putative 0.0798 0.3041 0.6427
Trypanosoma cruzi dihydrolipoamide dehydrogenase, putative 0.0052 0.0119 0.0419
Brugia malayi hypothetical protein 0.0448 0.1671 0.1921
Loa Loa (eye worm) hypothetical protein 0.0038 0.0066 0.0076
Trichomonas vaginalis chromodomain helicase DNA binding protein, putative 0.0052 0.012 0.0251
Entamoeba histolytica cysteine protease, putative 0.0103 0.0318 0.3517
Schistosoma mansoni transcription factor LCR-F1 0.0074 0.0205 0.0195
Brugia malayi heat shock protein 90 0.0098 0.0299 0.0338
Brugia malayi PHD-finger family protein 0.0024 0.0009 0.0004
Trypanosoma cruzi cruzipain precursor, putative 0.0052 0.012 0.0423
Brugia malayi Protein kinase domain containing protein 0.0719 0.2729 0.3142
Schistosoma mansoni inositol monophosphatase 0.0074 0.0207 0.0198
Loa Loa (eye worm) hypothetical protein 0.0052 0.012 0.0138
Trichomonas vaginalis rod cGMP-specific 3,5-cyclic phosphodiesterase, putative 0.0059 0.0147 0.0309
Plasmodium falciparum ataxin-2 like protein, putative 0.0075 0.021 0.1476
Trypanosoma brucei heat shock protein, putative 0.0098 0.0299 0.3068
Loa Loa (eye worm) hypothetical protein 0.0029 0.0028 0.0032
Trichomonas vaginalis conserved hypothetical protein 0.0051 0.0114 0.0237
Trypanosoma cruzi major cysteine proteinase, putative 0.0097 0.0294 0.1038
Plasmodium falciparum ataxin-2 like protein, putative 0.0075 0.021 0.1476
Echinococcus granulosus polycomb protein SCMH1 0.0144 0.0481 0.0472
Brugia malayi Matrix metalloprotease, N-terminal domain containing protein 0.0043 0.0082 0.0088
Loa Loa (eye worm) hypothetical protein 0.0052 0.012 0.0138
Trichomonas vaginalis Clan CA, family C1, papain-like cysteine peptidase 0.0051 0.0114 0.0237
Brugia malayi MH2 domain containing protein 0.0242 0.0865 0.0991
Trichomonas vaginalis conserved hypothetical protein 0.0024 0.0009 0.0017
Leishmania major 2-oxoglutarate dehydrogenase, e3 component, lipoamidedehydrogenase-like protein 0.0052 0.0119 0.1184
Plasmodium falciparum serine repeat antigen 2 0.0051 0.0114 0.0765
Echinococcus granulosus JmjC domain containing protein 4 0.0029 0.0028 0.0019
Schistosoma mansoni hypothetical protein 0.0881 0.3367 0.336
Plasmodium vivax histone acetyltransferase GCN5, putative 0.006 0.015 0.1035
Trypanosoma brucei heat shock protein, putative 0.0098 0.0299 0.3068
Trichomonas vaginalis cAMP-specific phosphodiesterase, putative 0.004 0.0073 0.0152
Loa Loa (eye worm) glutathione reductase 0.015 0.0502 0.0579
Entamoeba histolytica cysteine proteinase, putative 0.0103 0.0318 0.3517
Trichomonas vaginalis conserved hypothetical protein 0.0041 0.0076 0.0157
Giardia lamblia Cysteine protease 0.0051 0.0114 0.0495
Echinococcus multilocularis polycomb protein SCMH1 0.0144 0.0481 0.0472
Trypanosoma brucei dihydrolipoamide dehydrogenase 0.0052 0.0119 0.1155
Leishmania major heat shock protein 83-1 0.0098 0.0299 0.309
Echinococcus granulosus heat shock protein 0.0098 0.0299 0.029
Echinococcus granulosus COUP TF:Svp nuclear hormone receptor 0.0082 0.0235 0.0225
Loa Loa (eye worm) O-glycosyl hydrolase family 30 protein 0.0798 0.3041 0.3506
Entamoeba histolytica fructose-1,6-bisphosphate aldolase, putative 0.0142 0.0471 0.5247
Brugia malayi Nuclear hormone receptor family member nhr-19 0.0082 0.0235 0.0263
Loa Loa (eye worm) hypothetical protein 0.025 0.0893 0.1029
Leishmania major dihydrolipoamide dehydrogenase, putative 0.0052 0.0119 0.1184
Schistosoma mansoni heat shock protein 0.0098 0.0299 0.029
Brugia malayi PHD-finger family protein 0.0089 0.0264 0.0297
Plasmodium falciparum serine repeat antigen 3 0.0051 0.0114 0.0765
Echinococcus granulosus cathepsin l1 0.0111 0.0349 0.034
Onchocerca volvulus 0.0144 0.0481 0.1004
Brugia malayi Corticotropin releasing factor receptor 2 precursor, putative 0.026 0.0932 0.1068
Trichomonas vaginalis conserved hypothetical protein 0.0041 0.0076 0.0157
Trichomonas vaginalis inhibitor of growth, putative 0.0024 0.0009 0.0017
Echinococcus granulosus cathepsin l cysteine peptidase 0.0111 0.0349 0.034
Mycobacterium ulcerans two component sensor histidine kinase DevS 0.0033 0.0045 0.0155
Plasmodium falciparum JmjC domain-containing protein, putative 0.0029 0.0028 0.0136
Loa Loa (eye worm) hypothetical protein 0.0281 0.1015 0.117
Trypanosoma cruzi cysteine peptidase, putative 0.0157 0.053 0.187
Trichomonas vaginalis set domain proteins, putative 0.123 0.473 1
Plasmodium falciparum dihydrolipoyl dehydrogenase, mitochondrial 0.0052 0.0119 0.0802
Leishmania major heat shock protein 83-1 0.0098 0.0299 0.309
Schistosoma mansoni tyrosine kinase 0.1186 0.4558 0.4553
Loa Loa (eye worm) hypothetical protein 0.0051 0.0114 0.0131
Entamoeba histolytica cysteine protease, putative 0.0103 0.0318 0.3517
Giardia lamblia Heat shock protein HSP 90-alpha 0.0084 0.0244 0.1967
Echinococcus multilocularis cAMP and cAMP inhibited cGMP 3',5' cyclic 0.0026 0.0018 0.0008
Schistosoma mansoni hypothetical protein 0.1741 0.6733 0.673
Leishmania major heat shock protein 83-1 0.0098 0.0299 0.309
Brugia malayi Nuclear hormone receptor-like 1 0.0043 0.0084 0.009
Echinococcus granulosus jumonji domain containing protein 0.0124 0.0401 0.0392
Trichomonas vaginalis glucosylceramidase, putative 0.0798 0.3041 0.6427
Leishmania major cathepsin L-like protease 0.0157 0.053 0.552
Schistosoma mansoni lamin 0.0026 0.0019 0.0009
Echinococcus granulosus cathepsin b 0.0745 0.2833 0.2826
Echinococcus multilocularis 0.069 0.2619 0.2612
Loa Loa (eye worm) CXXC zinc finger family protein 0.0181 0.0623 0.0719
Echinococcus multilocularis bromodomain adjacent to zinc finger domain 0.0442 0.1647 0.164
Echinococcus multilocularis neuropeptide s receptor 0.0467 0.1745 0.1737
Loa Loa (eye worm) hypothetical protein 0.0038 0.0066 0.0076
Schistosoma mansoni serine/threonine protein kinase 0.0024 0.0011 0.0002
Entamoeba histolytica Acid sphingomyelinase-like phosphodiesterase, putative 0.025 0.0893 1
Echinococcus granulosus lamin 0.0026 0.0019 0.0009
Plasmodium vivax serine-repeat antigen (SERA), putative 0.0051 0.0114 0.0765
Giardia lamblia Cathepsin B precursor 0.0051 0.0114 0.0495
Leishmania major cathepsin L-like protease 0.0157 0.053 0.552
Entamoeba histolytica cysteine protease, putative 0.0051 0.0114 0.121
Mycobacterium leprae Probable fructose bisphosphate aldolase Fba 0.0657 0.2487 1
Loa Loa (eye worm) matrixin family protein 0.0085 0.0247 0.0285
Loa Loa (eye worm) thioredoxin reductase 0.015 0.0502 0.0579
Trichomonas vaginalis conserved hypothetical protein 0.0024 0.0009 0.0017
Leishmania major cysteine peptidase A (CPA) 0.0111 0.0349 0.3616
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0111 0.0349 0.0736
Echinococcus granulosus inositol monophosphatase 1 0.0074 0.0207 0.0198
Trypanosoma brucei JmjC domain, hydroxylase, putative 0.0029 0.0028 0.0196
Trichomonas vaginalis glucosylceramidase, putative 0.0524 0.1966 0.4154
Echinococcus multilocularis JmjC domain containing protein 4 0.0029 0.0028 0.0019
Trichomonas vaginalis cAMP-specific phosphodiesterase, putative 0.0059 0.0147 0.0309
Schistosoma mansoni intermediate filament proteins 0.0026 0.0019 0.0009
Onchocerca volvulus Matrix metalloproteinase homolog 0.0078 0.022 0.0452
Onchocerca volvulus Alhambra homolog 0.0089 0.0264 0.0546
Trichomonas vaginalis Clan CA, family C1, cathepsin B-like cysteine peptidase 0.0265 0.0955 0.2016
Leishmania major heat shock protein, putative 0.0065 0.017 0.1731
Loa Loa (eye worm) PHD-finger family protein 0.0024 0.0009 0.0011
Trichomonas vaginalis cGMP-dependent 3,5-cyclic phosphodiesterase, putative 0.0059 0.0147 0.0309
Loa Loa (eye worm) hypothetical protein 0.0035 0.0053 0.0061
Brugia malayi Nuclear hormone receptor family member nhr-41 0.0082 0.0235 0.0263
Echinococcus granulosus neuropeptide receptor A26 0.0467 0.1745 0.1737
Loa Loa (eye worm) hypothetical protein 0.0038 0.0066 0.0076
Trichomonas vaginalis myo inositol monophosphatase, putative 0.0074 0.0207 0.0435
Trichomonas vaginalis Clan CA, family C1, papain-like cysteine peptidase 0.0111 0.0349 0.0736
Echinococcus granulosus nuclear receptor 2DBD gamma 0.0082 0.0235 0.0225
Echinococcus granulosus diuretic hormone 44 receptor GPRdih2 0.0082 0.0237 0.0228
Brugia malayi nuclear receptor NHR-88 0.0038 0.0066 0.0069
Trypanosoma cruzi heat shock protein 85, putative 0.0098 0.0299 0.1057
Trypanosoma cruzi heat shock protein 90, putative 0.0098 0.0299 0.1057
Trichomonas vaginalis conserved hypothetical protein 0.0041 0.0076 0.0157
Toxoplasma gondii histone lysine methyltransferase SET1 0.0369 0.136 0.9919
Trichomonas vaginalis Clan CA, family C1, cathepsin L or H-like cysteine peptidase 0.0051 0.0114 0.0237
Loa Loa (eye worm) hypothetical protein 0.0043 0.0084 0.0097
Echinococcus multilocularis suppression of tumorigenicity 18 protein 0.0164 0.0559 0.055
Echinococcus multilocularis cathepsin L 0.0103 0.0318 0.0309
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0157 0.053 0.5506
Trichomonas vaginalis Clan CA, family C1, cathepsin B-like cysteine peptidase 0.0051 0.0114 0.0237
Leishmania major basic transcription factor 3a, putative 0.0071 0.0194 0.1983
Trichomonas vaginalis calcium/calmodulin-dependent 3,5-cyclic nucleotide phosphodiesterase, putative 0.0026 0.0018 0.0035
Brugia malayi Cathepsin L-like precursor 0.0111 0.0349 0.0396
Schistosoma mansoni photoreceptor-specific nuclear receptor related 0.0082 0.0235 0.0225
Trichomonas vaginalis inositol monophosphatase, putative 0.0074 0.0207 0.0435
Echinococcus multilocularis cpg binding protein 0.0205 0.0717 0.0709
Trypanosoma cruzi heat shock protein 90, putative 0.0041 0.0076 0.0269
Trypanosoma brucei dihydrolipoamide dehydrogenase 0.0052 0.0119 0.1155
Brugia malayi Phosphatidylinositol 3- and 4-kinase family protein 0.0025 0.0014 0.0009
Schistosoma mansoni bromodomain containing protein 0.0468 0.1748 0.174
Loa Loa (eye worm) hypothetical protein 0.0038 0.0066 0.0076
Echinococcus granulosus serine protein kinase ATM 0.0025 0.0014 0.0004
Trichomonas vaginalis conserved hypothetical protein 0.0039 0.0067 0.014
Schistosoma mansoni jumonji/arid domain-containing protein 0.0132 0.0432 0.0423
Loa Loa (eye worm) cathepsin B 0.0265 0.0955 0.1101
Brugia malayi Nuclear hormone receptor family member nhr-19 0.0082 0.0235 0.0263
Echinococcus multilocularis insulin growth factor 1 receptor beta 0.0719 0.2729 0.2722
Schistosoma mansoni coup transcription factor 0.0082 0.0235 0.0225
Echinococcus multilocularis heat shock protein 90 0.0084 0.0244 0.0235
Schistosoma mansoni tyrosine kinase 0.1186 0.4558 0.4553
Schistosoma mansoni scm-relatedprotein containing 4 mbt domains (sfmbt) 0.0144 0.0481 0.0472
Trypanosoma cruzi trypanothione reductase, putative 0.015 0.0502 0.1772
Plasmodium falciparum zinc finger protein, putative 0.0035 0.0053 0.0317
Onchocerca volvulus 0.0082 0.0235 0.0483
Brugia malayi hypothetical protein 0.0043 0.0084 0.009
Loa Loa (eye worm) hypothetical protein 0.0177 0.061 0.0704
Brugia malayi Inositol-1 0.0074 0.0207 0.0232
Trichomonas vaginalis heat shock protein, putative 0.0057 0.0139 0.029
Loa Loa (eye worm) papain family cysteine protease containing protein 0.0051 0.0114 0.0131
Loa Loa (eye worm) hypothetical protein 0.0029 0.0028 0.0032
Giardia lamblia Hypothetical protein 0.0051 0.0114 0.0495
Brugia malayi Nuclear hormone receptor E75 0.0038 0.0066 0.0069
Loa Loa (eye worm) papain family cysteine protease containing protein 0.0051 0.0114 0.0131
Brugia malayi Nuclear hormone receptor E75 0.0038 0.0066 0.0069
Echinococcus multilocularis matrix metallopeptidase 7 (M10 family) 0.0127 0.0414 0.0405
Schistosoma mansoni myelin transcription factor 1 myt1 0.0164 0.0559 0.055
Brugia malayi cathepsin L-like precursor 0.0059 0.0145 0.016
Brugia malayi jmjC domain containing protein 0.0029 0.0028 0.0025
Loa Loa (eye worm) hypothetical protein 0.0029 0.0028 0.0032
Echinococcus granulosus cysteine protease 0.0103 0.0318 0.0309
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0157 0.053 0.5506
Trypanosoma brucei PHD-zinc-finger like domain containing protein, putative 0.0029 0.0029 0.0211
Plasmodium vivax SET domain containing protein 0.003 0.0034 0.0178
Echinococcus multilocularis histone lysine N methyltransferase MLL3 0.0051 0.0113 0.0104
Treponema pallidum heat shock protein 90 0.0092 0.0276 0.4455
Trichomonas vaginalis Clan CA, family C1, papain-like cysteine peptidase 0.0111 0.0349 0.0736
Trichomonas vaginalis chromobox protein, putative 0.0042 0.0079 0.0164
Schistosoma mansoni camp/cgmp cyclic nucleotide phosphodiesterase 0.0059 0.0147 0.0138
Echinococcus multilocularis cathepsin L 0.0051 0.0114 0.0104
Onchocerca volvulus Heterochromatin protein 1 homolog 0.0042 0.0079 0.0154
Brugia malayi alpha keto acid dehydrogenase complex, E3 component, lipoamide dehydrogenase 0.0038 0.0065 0.0067
Loa Loa (eye worm) hypothetical protein 0.0035 0.0053 0.0061
Echinococcus granulosus nuclear receptor 2DBD gamma 0.0038 0.0066 0.0057
Trichomonas vaginalis fructose-bisphosphate aldolase, putative 0.0142 0.0471 0.0994
Leishmania major cathepsin L-like protease 0.0157 0.053 0.552
Loa Loa (eye worm) hypothetical protein 0.0448 0.1671 0.1927
Loa Loa (eye worm) hypothetical protein 0.0038 0.0066 0.0076
Mycobacterium tuberculosis Probable peptidoglycan hydrolase 0.0043 0.0082 0.0307
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0157 0.053 0.5506
Schistosoma mansoni tyrosine kinase 0.0719 0.2729 0.2722
Echinococcus multilocularis thyroid hormone receptor alpha 0.0082 0.0235 0.0225
Schistosoma mansoni sex comb on midleg homolog 0.0144 0.0481 0.0472
Trichomonas vaginalis PIKK family atypical protein kinase 0.0025 0.0014 0.0026
Entamoeba histolytica hypothetical protein 0.0071 0.0194 0.2122
Trichomonas vaginalis Clan CA, family C1, cathepsin H-like cysteine peptidase 0.0051 0.0114 0.0237
Brugia malayi nuclear receptor NHR-88 0.0082 0.0235 0.0263
Trichomonas vaginalis helicase, putative 0.0041 0.0076 0.0157
Echinococcus granulosus thyroid hormone receptor alpha 0.0038 0.0066 0.0057
Brugia malayi Cathepsin L-like precursor 0.0111 0.0349 0.0396
Brugia malayi O-Glycosyl hydrolase family 30 protein 0.0798 0.3041 0.3502
Plasmodium vivax serine-repeat antigen 5 (SERA) 0.0051 0.0114 0.0765
Brugia malayi C2-HC type zinc finger protein C.e-MyT1 0.0164 0.0559 0.0638
Schistosoma mansoni hypothetical protein 0.005 0.011 0.0101
Loa Loa (eye worm) hypothetical protein 0.0038 0.0066 0.0076
Trypanosoma brucei heat shock protein, putative 0.0098 0.0299 0.3068
Trichomonas vaginalis conserved hypothetical protein 0.0041 0.0076 0.0157
Loa Loa (eye worm) hypothetical protein 0.0153 0.0513 0.0592
Echinococcus multilocularis dual 3',5' cyclic AMP and GMP phosphodiesterase 0.0059 0.0147 0.0138
Onchocerca volvulus 0.0111 0.0349 0.0726
Trichomonas vaginalis conserved hypothetical protein 0.0033 0.0046 0.0094
Loa Loa (eye worm) hypothetical protein 0.0045 0.0093 0.0108
Trichomonas vaginalis chromodomain helicase DNA binding protein, putative 0.0052 0.012 0.0251
Brugia malayi Thioredoxin reductase 0.015 0.0502 0.0572
Mycobacterium tuberculosis Dihydrolipoamide dehydrogenase LpdC (lipoamide reductase (NADH)) (lipoyl dehydrogenase) (dihydrolipoyl dehydrogenase) (diaphoras 0.038 0.1403 0.5628
Echinococcus granulosus insulin growth factor 1 receptor beta 0.0719 0.2729 0.2722
Echinococcus granulosus neuropeptide s receptor 0.0467 0.1745 0.1737
Schistosoma mansoni jumonji domain containing protein 0.0029 0.0028 0.0019
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0157 0.053 0.5506
Plasmodium vivax vivapain-2 0.0111 0.0349 0.2496
Entamoeba histolytica papain family cysteine protease domain containing protein 0.0051 0.0114 0.121
Entamoeba histolytica cysteine protease, putative 0.0103 0.0318 0.3517
Loa Loa (eye worm) matrixin family protein 0.0078 0.022 0.0253
Brugia malayi nuclear hormone receptor family member odr-7 0.0038 0.0066 0.0069
Trichomonas vaginalis conserved hypothetical protein 0.0024 0.0009 0.0017
Plasmodium falciparum serine repeat antigen 8 0.0051 0.0114 0.0765
Schistosoma mansoni hypothetical protein 0.0089 0.0264 0.0255
Echinococcus granulosus nuclear receptor subfamily 4 group A 0.0038 0.0066 0.0057
Echinococcus multilocularis protein kinase c iota type 0.0094 0.0285 0.0276
Trypanosoma cruzi cysteine proteinase, putative 0.0103 0.0318 0.1123
Echinococcus multilocularis Nuclear hormone receptor HR96 0.0038 0.0066 0.0057
Entamoeba histolytica cysteine protease, putative 0.0103 0.0318 0.3517
Schistosoma mansoni tar DNA-binding protein 0.0254 0.091 0.0902
Onchocerca volvulus 0.017 0.058 0.1215
Schistosoma mansoni hepatocyte nuclear factor 4-alpha (hnf-4-alpha) 0.0038 0.0066 0.0057
Loa Loa (eye worm) ICD-1 protein 0.0071 0.0194 0.0224
Schistosoma mansoni subfamily C1A non-peptidase homologue (C01 family) 0.0051 0.0114 0.0104
Chlamydia trachomatis dihydrolipoyl dehydrogenase 0.0052 0.0119 0.5
Plasmodium vivax unspecified product 0.0052 0.012 0.0811
Brugia malayi Papain family cysteine protease containing protein 0.0051 0.0114 0.0124
Plasmodium vivax vivapain-1 0.0103 0.0318 0.2268
Brugia malayi cathepsin Z-like cysteine proteinase 0.0051 0.0114 0.0124
Loa Loa (eye worm) nuclear hormone receptor family member nhr-40 0.0082 0.0235 0.027
Onchocerca volvulus Glucosylceramidase homolog 0.0524 0.1966 0.4148
Echinococcus multilocularis neuropeptide receptor A26 0.0467 0.1745 0.1737
Echinococcus granulosus jumonji domain containing 1A 0.0029 0.0028 0.0019
Schistosoma mansoni subfamily C1A unassigned peptidase (C01 family) 0.0051 0.0114 0.0104
Schistosoma mansoni dihydrolipoamide dehydrogenase 0.0052 0.0119 0.0109
Echinococcus granulosus intermediate filament protein 0.0026 0.0019 0.0009
Loa Loa (eye worm) hypothetical protein 0.0024 0.0009 0.0011
Trichomonas vaginalis chromodomain helicase DNA binding protein, putative 0.0052 0.012 0.0251
Brugia malayi Papain family cysteine protease containing protein 0.0051 0.0114 0.0124
Onchocerca volvulus 0.0111 0.0349 0.0726
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0111 0.0349 0.0736
Trichomonas vaginalis Clan CA, family C1, papain-like cysteine peptidase 0.0051 0.0114 0.0237
Entamoeba histolytica cysteine protease, putative 0.0103 0.0318 0.3517
Echinococcus granulosus tumor protein p63 0.0341 0.1251 0.1243
Loa Loa (eye worm) hypothetical protein 0.0082 0.0235 0.027
Brugia malayi cathepsin B-like cysteine proteinase 0.0745 0.2833 0.3262
Trypanosoma brucei cysteine peptidase C (CPC) 0.0265 0.0955 1
Schistosoma mansoni sex comb on midleg homolog 0.0144 0.0481 0.0472
Onchocerca volvulus Tyrosine kinase homolog 0.0452 0.1687 0.3558
Leishmania major heat shock protein 83-1 0.0098 0.0299 0.309
Toxoplasma gondii histone lysine demethylase JMJD6a 0.0029 0.0028 0.0136
Trichomonas vaginalis chromodomain helicase DNA binding protein, putative 0.0052 0.012 0.0251
Trypanosoma cruzi dihydrolipoamide dehydrogenase, putative 0.0052 0.0119 0.0419
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0111 0.0349 0.0736
Mycobacterium ulcerans dihydrolipoamide dehydrogenase 0.0052 0.0119 0.0452
Brugia malayi Hypothetical C28H8.9 in chromosome III 0.0024 0.0009 0.0004
Trypanosoma brucei heat shock protein, putative 0.0098 0.0299 0.3068
Trichomonas vaginalis high-affinity cGMP-specific 3,5-cyclic phosphodiesterase, putative 0.0026 0.0018 0.0035
Trypanosoma brucei cAMP-specific phosphodiesterase 0.0059 0.0147 0.146
Schistosoma mansoni endoplasmin 0.0098 0.0299 0.029
Giardia lamblia Cathepsin B precursor 0.0265 0.0955 1
Loa Loa (eye worm) pigment dispersing factor receptor c 0.026 0.0932 0.1075
Loa Loa (eye worm) hypothetical protein 0.0038 0.0066 0.0076
Trichomonas vaginalis high-affinity cGMP-specific 3,5-cyclic phosphodiesterase, putative 0.0059 0.0147 0.0309
Schistosoma mansoni retinoid-x-receptor (RXR) 0.0043 0.0084 0.0075
Brugia malayi Nuclear hormone receptor-like 1 0.0082 0.0235 0.0263
Toxoplasma gondii cathepsin CPC2 0.0051 0.0114 0.0765
Schistosoma mansoni cpg binding protein 0.0205 0.0717 0.0709
Loa Loa (eye worm) RNA recognition domain-containing protein domain-containing protein 0.0254 0.091 0.105
Echinococcus multilocularis guanine nucleotide binding protein G(s) subunit 0.0143 0.0477 0.0468
Echinococcus multilocularis histone lysine N methyltransferase SETMAR 0.0158 0.0536 0.0527
Leishmania major heat shock protein 83-1 0.0098 0.0299 0.309
Onchocerca volvulus 0.0051 0.0114 0.0227
Entamoeba histolytica cysteine protease, putative 0.0103 0.0318 0.3517
Brugia malayi Bromodomain containing protein 0.011 0.0345 0.039
Echinococcus granulosus endoplasmin 0.0092 0.0276 0.0267
Brugia malayi Papain family cysteine protease containing protein 0.0111 0.0349 0.0396
Echinococcus granulosus histone acetyltransferase KAT2B 0.0142 0.0472 0.0463
Schistosoma mansoni Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) 0.0143 0.0477 0.0468
Schistosoma mansoni nuclear hormone receptor 0.0038 0.0066 0.0057
Loa Loa (eye worm) hypothetical protein 0.0045 0.009 0.0104
Loa Loa (eye worm) CHromoDomain protein family member 0.0035 0.0054 0.0062
Plasmodium vivax endoplasmin, putative 0.0098 0.0299 0.213
Onchocerca volvulus Cathepsin F homolog 0.0111 0.0349 0.0726
Trichomonas vaginalis endoplasmin, putative 0.0071 0.0194 0.0407
Echinococcus multilocularis lamin dm0 0.0026 0.0019 0.0009
Trypanosoma cruzi cAMP specific phosphodiesterase, putative 0.0059 0.0147 0.052
Trypanosoma cruzi dihydrolipoyl dehydrogenase, putative 0.0052 0.0119 0.0419
Schistosoma mansoni cathepsin B (C01 family) 0.0051 0.0114 0.0104
Schistosoma mansoni bromodomain containing protein 0.0045 0.009 0.0081
Plasmodium vivax dipeptidyl aminopeptidase 3, putative 0.0051 0.0114 0.0765
Plasmodium falciparum endoplasmin, putative 0.0071 0.0194 0.1356
Trichomonas vaginalis Clan CA, family C1, papain-like cysteine peptidase 0.0051 0.0114 0.0237
Entamoeba histolytica hypothetical protein 0.0025 0.0014 0.0084
Onchocerca volvulus Bile acid receptor homolog 0.0082 0.0235 0.0483
Brugia malayi Nuclear hormone receptor family member nhr-14 0.0082 0.0235 0.0263
Schistosoma mansoni cathepsin C 0.0051 0.0114 0.0104
Schistosoma mansoni phd/f-box containing protein 0.0029 0.0028 0.0019
Brugia malayi dihydrolipoyl dehydrogenase, mitochondrial precursor, putative 0.0052 0.0119 0.013
Entamoeba histolytica Acid sphingomyelinase-like phosphodiesterase, putative 0.025 0.0893 1
Entamoeba histolytica hypothetical protein 0.0051 0.0114 0.121
Brugia malayi nuclear hormone receptor 0.0038 0.0066 0.0069
Leishmania major heat shock protein 83-1 0.0098 0.0299 0.309
Loa Loa (eye worm) hypothetical protein 0.0089 0.0264 0.0305
Trypanosoma cruzi heat shock protein 90, putative 0.0084 0.0244 0.0861
Giardia lamblia Encystation-specific protease 0.0051 0.0114 0.0495
Mycobacterium ulcerans aldehyde dehydrogenase 0.0061 0.0156 0.0603
Giardia lamblia Heat shock protein HSP 90-alpha 0.0098 0.0299 0.2594
Brugia malayi Nuclear hormone receptor family member nhr-1 0.0082 0.0235 0.0263
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0051 0.0114 0.0237
Schistosoma mansoni lozenge 0.0056 0.0136 0.0126
Loa Loa (eye worm) fibroinase 0.0111 0.0349 0.0403
Echinococcus multilocularis chromobox protein 1 0.0069 0.0187 0.0177
Schistosoma mansoni cathepsin B-like peptidase (C01 family) 0.0051 0.0114 0.0104
Trypanosoma cruzi major cysteine proteinase, putative 0.0051 0.0114 0.0401
Brugia malayi glutathione reductase 0.015 0.0502 0.0572
Schistosoma mansoni hypothetical protein 0.0177 0.061 0.0601
Schistosoma mansoni hypothetical protein 0.0082 0.0237 0.0228
Schistosoma mansoni tyrosine kinase 0.1204 0.4631 0.4626
Plasmodium vivax SET domain protein, putative 0.0158 0.0536 0.3866
Entamoeba histolytica hypothetical protein 0.0074 0.0205 0.2237
Loa Loa (eye worm) hypothetical protein 0.0082 0.0235 0.027
Trichomonas vaginalis chromobox protein, putative 0.0042 0.0079 0.0164
Echinococcus multilocularis nuclear receptor 2DBD gamma 0.0082 0.0235 0.0225
Schistosoma mansoni thyroid hormone receptor 0.0082 0.0235 0.0225
Onchocerca volvulus Cathepsin L homolog 0.0111 0.0349 0.0726
Mycobacterium tuberculosis Probable oxidoreductase 0.038 0.1403 0.5628
Echinococcus granulosus FTZ F1 nuclear receptor protein 0.0082 0.0235 0.0225
Schistosoma mansoni vesicular amine transporter 0.0029 0.0028 0.0019
Trichomonas vaginalis cAMP/cGMP cyclic nucleotide phosphodiesterase, putative 0.0059 0.0147 0.0309
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0111 0.0349 0.0736
Leishmania major heat shock protein 83-1 0.0098 0.0299 0.309
Schistosoma mansoni dipeptidyl-peptidase I (C01 family) 0.0051 0.0114 0.0104
Trypanosoma brucei heat shock protein 90, putative 0.0098 0.0299 0.3068
Trichomonas vaginalis heat shock protein, putative 0.0098 0.0299 0.063
Loa Loa (eye worm) runx1 0.0056 0.0136 0.0156
Trypanosoma cruzi heat shock protein, putative 0.0065 0.017 0.0602
Plasmodium vivax serine-repeat antigen (SERA) 0.0051 0.0114 0.0765
Echinococcus multilocularis heat shock protein 90 0.0098 0.0299 0.029
Loa Loa (eye worm) AGC/PKC/IOTA protein kinase 0.0092 0.0276 0.0319
Brugia malayi Cathepsin L-like precursor 0.0111 0.0349 0.0396
Loa Loa (eye worm) hypothetical protein 0.0082 0.0235 0.027
Loa Loa (eye worm) hypothetical protein 0.0082 0.0235 0.027
Trichomonas vaginalis Clan CA, family C1, cathepsin L or K-like cysteine peptidase 0.0111 0.0349 0.0736
Plasmodium falciparum phd finger protein, putative 0.0089 0.0264 0.1871
Echinococcus granulosus chromobox protein 1 0.0069 0.0187 0.0177
Leishmania major lipophosphoglycan biosynthetic protein, putative,heat shock protein 90, putative,glucose regulated protein 94, putative 0.0092 0.0276 0.2841
Schistosoma mansoni cpg binding protein 0.0205 0.0717 0.0709
Mycobacterium leprae PROBABLE HYDROLASE 0.0043 0.0082 0.0307
Loa Loa (eye worm) hypothetical protein 0.0082 0.0235 0.027
Brugia malayi Cathepsin L-like cysteine proteinase 0.0059 0.0145 0.016
Echinococcus multilocularis nuclear receptor 2DBD gamma 0.0082 0.0235 0.0225
Loa Loa (eye worm) hypothetical protein 0.0053 0.0123 0.0142
Echinococcus multilocularis heat shock protein 0.0098 0.0299 0.029
Loa Loa (eye worm) MBCTL1 0.0164 0.0559 0.0644
Echinococcus granulosus Jumonji AT rich interactive domain 1B 0.0053 0.0122 0.0113
Schistosoma mansoni cathepsin B-like peptidase (C01 family) 0.0745 0.2833 0.2826
Brugia malayi calcium-independent alpha-latrotoxin receptor 2, putative 0.0082 0.0237 0.0266
Trichomonas vaginalis heat shock protein, putative 0.0092 0.0276 0.058
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0111 0.0349 0.0736
Onchocerca volvulus 0.0448 0.1671 0.3523
Entamoeba histolytica transcription factor BTF3, putative 0.0071 0.0194 0.2122
Echinococcus granulosus histone lysine methyltransferase setb 0.0281 0.1015 0.1006
Echinococcus multilocularis tar DNA binding protein 0.0254 0.091 0.0902
Brugia malayi PHD-finger family protein 0.0053 0.0123 0.0135
Plasmodium vivax dihydrolipoyl dehydrogenase, mitochondrial, putative 0.0052 0.0119 0.0802
Plasmodium falciparum serine repeat antigen 7 0.0051 0.0114 0.0765
Trichomonas vaginalis cone cGMP-specific 3,5-cyclic phosphodiesterase, putative 0.0059 0.0147 0.0309
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0103 0.0318 0.3266
Brugia malayi Furin-like cysteine rich region family protein 0.2236 0.8672 1
Mycobacterium ulcerans flavoprotein disulfide reductase 0.0052 0.0119 0.0452
Trichomonas vaginalis chromodomain helicase DNA binding protein, putative 0.0052 0.012 0.0251
Plasmodium falciparum glutathione reductase 0.0052 0.0119 0.0802
Plasmodium falciparum conserved Plasmodium membrane protein, unknown function 0.004 0.0073 0.0464
Mycobacterium tuberculosis Probable NADH dehydrogenase Ndh 0.0342 0.1253 0.5026
Plasmodium vivax vivapain-3 0.0103 0.0318 0.2268
Echinococcus multilocularis basement membrane specific heparan sulfate 0.0029 0.0028 0.0019
Leishmania major cathepsin L-like protease 0.0111 0.0349 0.3616
Echinococcus multilocularis musashi 0.0026 0.0019 0.0009
Trichomonas vaginalis conserved hypothetical protein 0.0039 0.0067 0.014
Brugia malayi Intermediate filament tail domain containing protein 0.0026 0.0019 0.0014
Trichomonas vaginalis heat shock protein, putative 0.0071 0.0194 0.0407
Plasmodium falciparum histone acetyltransferase GCN5 0.0039 0.007 0.0444
Toxoplasma gondii inositol(myo)-1(or 4)-monophosphatase 2, putative 0.0074 0.0207 0.1452
Trypanosoma cruzi Heat shock protein 83, putative 0.0098 0.0299 0.1057
Schistosoma mansoni cathepsin B-like peptidase (C01 family) 0.0051 0.0114 0.0104
Giardia lamblia NADH oxidase lateral transfer candidate 0.0052 0.0119 0.0552
Echinococcus multilocularis gcn5proteinral control of amino acid synthesis 0.0163 0.0555 0.0546
Loa Loa (eye worm) hypothetical protein 0.0038 0.0066 0.0076
Brugia malayi RNA recognition motif domain containing protein 0.0254 0.091 0.1043
Plasmodium vivax ataxin-2 like protein, putative 0.0075 0.021 0.1476
Mycobacterium tuberculosis NADPH-dependent mycothiol reductase Mtr 0.015 0.0502 0.1997
Loa Loa (eye worm) hypothetical protein 0.0038 0.0066 0.0076
Schistosoma mansoni matrix metallopeptidase-9 (M10 family) 0.0083 0.0241 0.0232
Trichomonas vaginalis cGMP-specific 3,5-cyclic phosphodiesterase, putative 0.0059 0.0147 0.0309
Trichomonas vaginalis glucosylceramidase, putative 0.0798 0.3041 0.6427
Loa Loa (eye worm) heat shock protein 90 0.0098 0.0299 0.0345
Echinococcus granulosus histone lysine N methyltransferase MLL3 0.0051 0.0113 0.0104
Brugia malayi PHD-finger family protein 0.0024 0.0009 0.0004
Trichomonas vaginalis mercuric reductase, putative 0.0052 0.0119 0.0248
Plasmodium vivax glutathione reductase, putative 0.015 0.0502 0.3618
Brugia malayi hypothetical protein 0.0029 0.0028 0.0025
Loa Loa (eye worm) hypothetical protein 0.0024 0.0009 0.0011
Echinococcus multilocularis jumonji domain containing protein 0.0124 0.0401 0.0392
Loa Loa (eye worm) hypothetical protein 0.032 0.1168 0.1347
Mycobacterium tuberculosis Probable chaperone protein HtpG (heat shock protein) (HSP90 family protein) (high temperature protein G) 0.0092 0.0276 0.1086
Loa Loa (eye worm) cysteine proteinase cathepsin Z 0.0051 0.0114 0.0131
Trichomonas vaginalis conserved hypothetical protein 0.0024 0.0009 0.0017
Loa Loa (eye worm) RNA binding protein 0.0254 0.091 0.105
Echinococcus granulosus tyrosine protein kinase transmembrane receptor 0.0026 0.0017 0.0007
Schistosoma mansoni hypothetical protein 0.0082 0.0237 0.0228
Schistosoma mansoni hypothetical protein 0.011 0.0345 0.0336
Schistosoma mansoni acetyl-CoA C-acetyltransferase 0.0172 0.0589 0.058
Toxoplasma gondii thioredoxin reductase 0.015 0.0502 0.3618
Trichomonas vaginalis conserved hypothetical protein 0.0041 0.0076 0.0157
Brugia malayi cathepsin F-like cysteine proteinase 0.0051 0.0114 0.0124
Plasmodium falciparum cysteine proteinase falcipain 2b 0.0111 0.0349 0.2496
Echinococcus granulosus heat shock protein heat shock protein 90 alpha 0.0084 0.0244 0.0235
Leishmania major hypothetical protein, conserved 0.011 0.0345 0.3574
Schistosoma mansoni nuclear receptor 0.0038 0.0066 0.0057
Onchocerca volvulus 0.0024 0.0009 0.0006
Echinococcus granulosus cathepsin L 0.0051 0.0114 0.0104
Brugia malayi GTP-binding regulatory protein Gs alpha-S chain, putative 0.0143 0.0477 0.0543
Schistosoma mansoni endoplasmin 0.0098 0.0299 0.029
Giardia lamblia Cathepsin L precursor 0.0051 0.0114 0.0495
Schistosoma mansoni hypothetical protein 0.0082 0.0237 0.0228
Echinococcus multilocularis neuroglian 0.0036 0.0057 0.0047
Giardia lamblia Cathepsin L-like protease 0.0051 0.0114 0.0495
Brugia malayi PHD-finger family protein 0.0193 0.067 0.0766
Leishmania major heat shock protein 83-1 0.0098 0.0299 0.309
Echinococcus granulosus FTZ F1 alpha 0.0082 0.0235 0.0225
Leishmania major myo-inositol-1(or 4)-monophosphatase 1, putative 0.0074 0.0207 0.2117
Entamoeba histolytica cysteine proteinase, putative 0.0103 0.0318 0.3517
Schistosoma mansoni retinoic acid receptor RXR 0.0082 0.0235 0.0225
Loa Loa (eye worm) TK/FAK protein kinase 0.0806 0.307 0.354
Schistosoma mansoni inositol monophosphatase 0.0074 0.0207 0.0198
Loa Loa (eye worm) hypothetical protein 0.0507 0.1903 0.2194
Schistosoma mansoni methyl-cpg binding protein mbd 0.0122 0.0395 0.0386
Echinococcus multilocularis cathepsin l cysteine peptidase 0.0111 0.0349 0.034
Schistosoma mansoni mixed-lineage leukemia protein mll 0.008 0.0227 0.0218
Schistosoma mansoni defective proboscis extension response (dpr)-related 0.0029 0.0028 0.0019
Echinococcus multilocularis endonuclease exonuclease phosphatase 0.0573 0.2158 0.215
Toxoplasma gondii PHD-finger domain-containing protein 0.0089 0.0264 0.1871
Trichomonas vaginalis cat eye syndrome critical region protein 2, cscr2, putative 0.006 0.015 0.0315
Echinococcus granulosus twitchin 0.0036 0.0057 0.0048
Brugia malayi jmjC domain containing protein 0.0029 0.0028 0.0025
Onchocerca volvulus 0.005 0.011 0.0219
Loa Loa (eye worm) MH2 domain-containing protein 0.0242 0.0865 0.0997
Onchocerca volvulus Protein ultraspiracle homolog 0.0082 0.0235 0.0483
Entamoeba histolytica cysteine protease, putative 0.0103 0.0318 0.3517
Schistosoma mansoni hypothetical protein 0.1741 0.6733 0.673
Echinococcus multilocularis inositol monophosphatase 1 0.0074 0.0207 0.0198
Plasmodium falciparum glutathione reductase 0.015 0.0502 0.3618
Loa Loa (eye worm) hypothetical protein 0.0029 0.0028 0.0032
Echinococcus granulosus thioredoxin glutathione reductase 0.015 0.0502 0.0493
Trichomonas vaginalis Clan CA, family C1, papain-like cysteine peptidase 0.0111 0.0349 0.0736
Plasmodium vivax basic transcription factor 3b, putative 0.0071 0.0194 0.1359
Toxoplasma gondii hypothetical protein 0.0052 0.0119 0.0804
Onchocerca volvulus 0.0024 0.0009 0.0006
Trichomonas vaginalis Clan CA, family C1, papain-like cysteine peptidase 0.0111 0.0349 0.0736
Schistosoma mansoni subfamily C1A unassigned peptidase (C01 family) 0.0051 0.0114 0.0104
Loa Loa (eye worm) hypothetical protein 0.0043 0.0082 0.0095
Loa Loa (eye worm) papain family cysteine protease containing protein 0.0052 0.012 0.0138
Mycobacterium tuberculosis Probable membrane NADH dehydrogenase NdhA 0.0342 0.1253 0.5026
Trichomonas vaginalis glucosylceramidase, putative 0.0798 0.3041 0.6427
Echinococcus multilocularis microtubule associated protein 2 0.1375 0.5299 0.5294
Loa Loa (eye worm) endoplasmin 0.0098 0.0299 0.0345
Loa Loa (eye worm) hypothetical protein 0.0275 0.0994 0.1146
Echinococcus granulosus histone lysine N methyltransferase MLL3 0.0062 0.0157 0.0147
Giardia lamblia Cathepsin B precursor 0.0265 0.0955 1
Echinococcus multilocularis zinc finger protein 0.0154 0.052 0.0511
Entamoeba histolytica cysteine protease, putative 0.0103 0.0318 0.3517
Echinococcus multilocularis histone lysine N methyltransferase MLL3 0.0062 0.0157 0.0147
Echinococcus multilocularis guanine nucleotide binding protein G(s) subunit 0.0143 0.0477 0.0468
Brugia malayi Nuclear hormone receptor-like 1 0.0043 0.0084 0.009
Echinococcus multilocularis muscleblind protein 0.0151 0.0506 0.0497
Loa Loa (eye worm) hypothetical protein 0.005 0.0111 0.0128
Schistosoma mansoni jumonji domain containing protein 0.0232 0.0823 0.0814
Echinococcus granulosus bromodomain adjacent to zinc finger domain 0.0442 0.1647 0.164
Echinococcus multilocularis chromobox protein 1 0.0069 0.0187 0.0177
Schistosoma mansoni cathepsin B-like peptidase (C01 family) 0.0745 0.2833 0.2826
Mycobacterium leprae DIHYDROLIPOAMIDE DEHYDROGENASE LPD (LIPOAMIDE REDUCTASE (NADH)) (LIPOYL DEHYDROGENASE) (DIHYDROLIPOYL DEHYDROGENASE) (DIAPHORASE 0.038 0.1403 0.5628
Trichomonas vaginalis glucosylceramidase, putative 0.0524 0.1966 0.4154
Echinococcus granulosus endonuclease exonuclease phosphatase 0.0573 0.2158 0.215
Onchocerca volvulus Nuclear receptor subfamily 6 group A member 1 homolog 0.0038 0.0066 0.0126
Loa Loa (eye worm) hypothetical protein 0.0024 0.0009 0.0011
Brugia malayi nuclear receptor RXR 0.0038 0.0066 0.0069
Mycobacterium ulcerans aldehyde dehydrogenase 0.0061 0.0156 0.0603
Echinococcus granulosus guanine nucleotide binding protein Gs subunit 0.0143 0.0477 0.0468
Brugia malayi cathepsin L-like cysteine proteinase 0.0051 0.0114 0.0124
Trichomonas vaginalis glucosylceramidase, putative 0.0552 0.2076 0.4388
Leishmania major cathepsin L-like protease 0.0111 0.0349 0.3616
Loa Loa (eye worm) Papain cysteine protease/cathepsin propeptide inhibitor-containing protein 0.0111 0.0349 0.0403
Schistosoma mansoni cellular tumor antigen P53 0.005 0.0111 0.0102
Trichomonas vaginalis fructose-bisphosphate aldolase, putative 0.0142 0.0471 0.0994
Treponema pallidum fructose-bisphosphate aldolase 0.0142 0.0471 1
Schistosoma mansoni retinoid-x-receptor (RXR) 0.0082 0.0235 0.0225
Echinococcus multilocularis cathepsin l cysteine peptidase 0.0111 0.0349 0.034
Loa Loa (eye worm) hypothetical protein 0.0059 0.0145 0.0167
Echinococcus granulosus ecdysone induced protein 78C 0.0082 0.0235 0.0225
Trypanosoma cruzi dihydrolipoamide dehydrogenase, putative 0.0052 0.0119 0.0419
Loa Loa (eye worm) TK protein kinase 0.0026 0.0017 0.0019
Plasmodium vivax unspecified product 0.0103 0.0318 0.2268
Giardia lamblia Cathepsin B precursor 0.0051 0.0114 0.0495
Loa Loa (eye worm) hypothetical protein 0.0151 0.0506 0.0583
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0051 0.0114 0.0237
Trichomonas vaginalis Clan CA, family C1, cathepsin B-like cysteine peptidase 0.0051 0.0114 0.0237
Toxoplasma gondii NADPH-glutathione reductase 0.0052 0.0119 0.0802
Brugia malayi SET domain containing protein 0.0034 0.0047 0.0047
Echinococcus multilocularis serine protein kinase ATM 0.0025 0.0014 0.0004
Brugia malayi Protein kinase domain containing protein 0.0806 0.307 0.3535
Echinococcus multilocularis PHD finger protein rhinoceros 0.0089 0.0264 0.0255
Entamoeba histolytica 90 kDa heat shock protein, putative 0.0065 0.017 0.1852
Echinococcus multilocularis COUP TF:Svp nuclear hormone receptor 0.0082 0.0235 0.0225
Echinococcus multilocularis Basic leucine zipper (bZIP) transcription 0.0074 0.0205 0.0195
Loa Loa (eye worm) hypothetical protein 0.0029 0.0028 0.0032
Trypanosoma cruzi JmjC domain, hydroxylase, putative 0.0029 0.0028 0.0099
Brugia malayi TAR-binding protein 0.0254 0.091 0.1043
Schistosoma mansoni Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) 0.0143 0.0477 0.0468
Loa Loa (eye worm) hypothetical protein 0.026 0.0932 0.1075
Echinococcus granulosus dual 3'5' cyclic AMP and GMP phosphodiesterase 0.0059 0.0147 0.0138
Loa Loa (eye worm) hypothetical protein 0.0023 0.0006 0.0007
Brugia malayi mbt repeat family protein 0.0144 0.0481 0.0547
Echinococcus granulosus cathepsin L cysteine protease 0.0103 0.0318 0.0309
Plasmodium vivax serine-repeat antigen 4 (SERA) 0.0051 0.0114 0.0765
Plasmodium vivax heat shock protein 90, putative 0.0065 0.017 0.1183
Echinococcus granulosus mixed lineage leukemia protein mll 0.0051 0.0113 0.0104
Loa Loa (eye worm) inositol-1 0.0074 0.0207 0.0239
Echinococcus multilocularis diuretic hormone 44 receptor GPRdih2 0.0082 0.0237 0.0228
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0111 0.0349 0.0736
Schistosoma mansoni hypothetical protein 0.2575 1 1
Echinococcus granulosus muscleblind protein 0.0151 0.0506 0.0497
Schistosoma mansoni Neurotrimin precursor (hNT) 0.0029 0.0028 0.0019
Giardia lamblia Hypothetical protein 0.0051 0.0114 0.0495
Plasmodium falciparum dipeptidyl aminopeptidase 3 0.0051 0.0114 0.0765
Echinococcus granulosus tar DNA binding protein 0.0254 0.091 0.0902
Trichomonas vaginalis conserved hypothetical protein 0.0051 0.0114 0.0237
Schistosoma mansoni nuclear hormone receptor 0.0038 0.0066 0.0057
Brugia malayi CHD4 protein 0.0035 0.0054 0.0055
Echinococcus multilocularis lysine specific demethylase 6a 0.0029 0.0028 0.0019
Echinococcus multilocularis cathepsin b 0.0745 0.2833 0.2826
Loa Loa (eye worm) nuclear hormone receptor family member nhr-49 0.0082 0.0235 0.027
Plasmodium vivax hypothetical protein, conserved 0.004 0.0073 0.0464
Brugia malayi hypothetical protein 0.0038 0.0066 0.0069
Trichomonas vaginalis chromodomain helicase DNA binding protein, putative 0.003 0.0034 0.0069
Brugia malayi Pre-SET motif family protein 0.1081 0.4148 0.4779
Loa Loa (eye worm) jmjC domain-containing protein 0.0029 0.0028 0.0032
Trypanosoma cruzi cAMP specific phosphodiesterase, putative 0.004 0.0073 0.0259
Leishmania major heat shock protein 83-1 0.0098 0.0299 0.309
Onchocerca volvulus 0.0024 0.0009 0.0006
Schistosoma mansoni Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) 0.0143 0.0477 0.0468
Echinococcus multilocularis cysteine protease 0.0111 0.0349 0.034
Loa Loa (eye worm) TAR-binding protein 0.0254 0.091 0.105
Onchocerca volvulus Cathepsin L homolog 0.0111 0.0349 0.0726
Trichomonas vaginalis cGMP-specific 3,5-cyclic phosphodiesterase, putative 0.0059 0.0147 0.0309
Schistosoma mansoni nuclear receptor 2DBD-gamma 0.0082 0.0235 0.0225
Giardia lamblia Grp94/Hsp90 0.0092 0.0276 0.2328
Leishmania major heat shock protein 83-1 0.0098 0.0299 0.309
Schistosoma mansoni atypical protein kinase C 0.01 0.0308 0.0299
Echinococcus multilocularis jumonji domain containing 1A 0.0029 0.0028 0.0019
Brugia malayi hypothetical protein 0.0043 0.0084 0.009
Trichomonas vaginalis Clan CA, family C1, cathepsin F-like cysteine peptidase 0.0051 0.0114 0.0237
Trichomonas vaginalis cAMP-specific phosphodiesterase, putative 0.0059 0.0147 0.0309
Loa Loa (eye worm) hypothetical protein 0.0296 0.1074 0.1239
Trichomonas vaginalis conserved hypothetical protein 0.0052 0.0119 0.0248
Loa Loa (eye worm) cysteine protease 0.0111 0.0349 0.0403
Trypanosoma cruzi Ring finger domain/PHD-finger, putative 0.0024 0.0009 0.0033
Brugia malayi Immunoglobulin I-set domain containing protein 0.0029 0.0028 0.0025
Trichomonas vaginalis conserved hypothetical protein 0.0041 0.0076 0.0157
Loa Loa (eye worm) jmjC domain-containing protein 0.0132 0.0432 0.0498
Echinococcus multilocularis histone acetyltransferase MYST2 0.0164 0.0559 0.055
Echinococcus granulosus protein kinase c iota type 0.0094 0.0285 0.0276
Trichomonas vaginalis cGMP-specific 3,5-cyclic phosphodiesterase, putative 0.0059 0.0147 0.0309
Plasmodium falciparum basic transcription factor 3b, putative 0.0071 0.0194 0.1359
Entamoeba histolytica cysteine protease, putative 0.0051 0.0114 0.121
Echinococcus granulosus Nuclear hormone receptor HR96 0.0038 0.0066 0.0057
Trypanosoma cruzi myo-inositol-1(or 4)-monophosphatase 1, putative 0.0074 0.0207 0.0731
Entamoeba histolytica cysteine protease, putative 0.0051 0.0114 0.121
Echinococcus multilocularis tyrosine protein kinase transmembrane receptor 0.0026 0.0017 0.0007
Trypanosoma brucei transcription factor BTF3, putative 0.0071 0.0194 0.1957
Trypanosoma cruzi dihydrolipoyl dehydrogenase, putative 0.0052 0.0119 0.0419
Brugia malayi orphan nuclear receptor NR2E1 0.0038 0.0066 0.0069
Trypanosoma cruzi cysteine peptidase, putative 0.0111 0.0349 0.1233
Brugia malayi Heterochromatin protein 1 0.0069 0.0187 0.0208
Echinococcus granulosus heat shock protein 90 0.0098 0.0299 0.029
Trichomonas vaginalis fructose-bisphosphate aldolase, putative 0.0142 0.0471 0.0994
Schistosoma mansoni FTZ-F1 nuclear receptor-like protein 0.0082 0.0235 0.0225
Echinococcus multilocularis dihydrolipoamide dehydrogenase 0.0052 0.0119 0.0109
Leishmania major cathepsin L-like protease 0.0111 0.0349 0.3616
Echinococcus granulosus neurotracting:lsamp:neurotrimin:obcam 0.0038 0.0065 0.0055
Schistosoma mansoni hypothetical protein 0.0074 0.0205 0.0195
Trichomonas vaginalis cAMP-specific 3,5-cyclic phosphodiesterase, putative 0.0059 0.0147 0.0309
Loa Loa (eye worm) intermediate filament protein 0.0026 0.0019 0.0022
Onchocerca volvulus 0.0111 0.0349 0.0726
Trichomonas vaginalis cAMP-specific 3,5-cyclic phosphodiesterase, putative 0.0059 0.0147 0.0309
Schistosoma mansoni tyrosine kinase 0.2236 0.8672 0.8671
Mycobacterium ulcerans extragenic suppressor protein SuhB 0.0074 0.0207 0.0809
Loa Loa (eye worm) TK/ROR protein kinase 0.0026 0.0017 0.0019
Trypanosoma brucei phosphatidylinositol kinase related protein, putative 0.0025 0.0014 0.0047
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0059 0.0145 0.0303
Toxoplasma gondii FATC domain-containing protein 0.0025 0.0014 0.0032
Echinococcus granulosus cathepsin L cysteine proteinase 0.0111 0.0349 0.034
Brugia malayi Ligand-binding domain of nuclear hormone receptor family protein 0.0082 0.0235 0.0263
Loa Loa (eye worm) jmjC domain-containing protein 0.0029 0.0028 0.0032
Brugia malayi cathepsin L precursor 0.0051 0.0114 0.0124
Trypanosoma cruzi cysteine proteinase, putative 0.0103 0.0318 0.1123
Onchocerca volvulus Nuclear receptor subfamily 6 group A member 1 homolog 0.0038 0.0066 0.0126
Trypanosoma brucei PHD-zinc-finger like domain containing protein, putative 0.0029 0.0029 0.0211
Loa Loa (eye worm) heat shock protein 75 0.0065 0.017 0.0197
Leishmania major heat shock protein 83-1 0.0098 0.0299 0.309
Loa Loa (eye worm) hypothetical protein 0.0029 0.0028 0.0032
Trichomonas vaginalis conserved hypothetical protein 0.0024 0.0009 0.0017
Loa Loa (eye worm) nuclear hormone receptor-like 1 0.0043 0.0084 0.0097
Loa Loa (eye worm) TK/INSR protein kinase 0.0719 0.2729 0.3147
Plasmodium vivax serine-repeat antigen (SERA) 0.0051 0.0114 0.0765
Giardia lamblia Cathepsin B precursor 0.0051 0.0114 0.0495
Leishmania major cathepsin L-like protease 0.0111 0.0349 0.3616
Brugia malayi Pre-SET motif family protein 0.0158 0.0536 0.0611
Schistosoma mansoni histone-lysine n-methyltransferase setb1 0.0281 0.1015 0.1006
Brugia malayi Muscleblind-like protein 0.0151 0.0506 0.0576
Onchocerca volvulus 0.0035 0.0053 0.0098
Trichomonas vaginalis conserved hypothetical protein 0.0041 0.0076 0.0157
Echinococcus multilocularis heat shock protein 75 kDa, mitochondrial 0.0065 0.017 0.0161
Brugia malayi conserved hypotetical protein 0.0038 0.0066 0.0069
Onchocerca volvulus 0.0026 0.0019 0.0026
Onchocerca volvulus 0.0111 0.0349 0.0726
Brugia malayi ecdysone receptor 0.0038 0.0066 0.0069
Schistosoma mansoni bromodomain-containing nuclear protein 1 brd1 0.0089 0.0264 0.0255
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0111 0.0349 0.0736
Echinococcus granulosus peregrin 0.011 0.0345 0.0336
Schistosoma mansoni hypothetical protein 0.0034 0.0048 0.0038
Trichomonas vaginalis chromodomain helicase DNA binding protein, putative 0.0052 0.012 0.0251
Loa Loa (eye worm) hypothetical protein 0.0043 0.0084 0.0097
Echinococcus multilocularis lamin 0.0026 0.0019 0.0009
Toxoplasma gondii cathepsin B 0.0265 0.0955 0.6944
Plasmodium vivax serine-repeat antigen (SERA), putative 0.0051 0.0114 0.0765
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0157 0.053 0.5506
Schistosoma mansoni aldehyde dehydrogenase 0.0061 0.0156 0.0147
Plasmodium vivax unspecified product 0.0051 0.0114 0.0765
Schistosoma mansoni SmCL2-like peptidase (C01 family) 0.0103 0.0318 0.0309
Brugia malayi Bromodomain containing protein 0.0278 0.1006 0.1153
Giardia lamblia Cathepsin L precursor 0.0051 0.0114 0.0495
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0157 0.053 0.5506
Entamoeba histolytica cysteine protease, putative 0.0051 0.0114 0.121
Trypanosoma cruzi transcription factor btf3, putative 0.0071 0.0194 0.0686
Schistosoma mansoni cathepsin B-like peptidase (C01 family) 0.0051 0.0114 0.0104
Trichomonas vaginalis Clan CA, family C1, cathepsin B-like cysteine peptidase 0.0051 0.0114 0.0237
Brugia malayi Papain family cysteine protease containing protein 0.0103 0.0318 0.036
Brugia malayi hypothetical protein 0.0038 0.0066 0.0069
Trichomonas vaginalis glucosylceramidase, putative 0.0798 0.3041 0.6427
Leishmania major dihydrolipoamide dehydrogenase, putative 0.0052 0.0119 0.1184
Loa Loa (eye worm) hypothetical protein 0.0464 0.1732 0.1997
Giardia lamblia Dipeptidyl-peptidase I precursor 0.0051 0.0114 0.0495
Wolbachia endosymbiont of Brugia malayi fructose-1,6-bisphosphatase 0.0074 0.0207 0.5631
Giardia lamblia Cysteine protease 0.0051 0.0114 0.0495
Loa Loa (eye worm) hypothetical protein 0.0059 0.0145 0.0167
Toxoplasma gondii cathepsin CPL 0.0111 0.0349 0.2496
Loa Loa (eye worm) jmjC domain-containing protein 0.0184 0.0636 0.0733
Leishmania major heat shock protein 83-1 0.0098 0.0299 0.309
Echinococcus granulosus neuroglian 0.0036 0.0057 0.0047
Plasmodium vivax JmjC domain containing protein 0.0029 0.0028 0.0136
Loa Loa (eye worm) hypothetical protein 0.0024 0.0009 0.0011
Mycobacterium tuberculosis Probable fructose-bisphosphate aldolase Fba 0.0657 0.2487 1
Loa Loa (eye worm) hypothetical protein 0.0164 0.0559 0.0644
Schistosoma mansoni cathepsin F (C01 family) 0.0111 0.0349 0.034
Trichomonas vaginalis myo inositol monophosphatase, putative 0.0074 0.0207 0.0435
Entamoeba histolytica cysteine proteinase, putative 0.0111 0.0349 0.3869
Plasmodium falciparum serine repeat antigen 5 0.0051 0.0114 0.0765
Schistosoma mansoni chromobox protein 0.0069 0.0187 0.0177
Onchocerca volvulus 0.0464 0.1732 0.3652
Echinococcus granulosus epidermal growth factor receptor 0.2236 0.8672 0.8671
Echinococcus granulosus retinoic acid receptor rxr beta a 0.0082 0.0235 0.0225
Brugia malayi Nuclear hormone receptor family member nhr-49 0.0082 0.0235 0.0263
Mycobacterium tuberculosis Two component sensor histidine kinase DevS 0.0033 0.0045 0.0155
Mycobacterium ulcerans aldehyde dehydrogenase 0.0061 0.0156 0.0603
Schistosoma mansoni heat shock protein 0.0065 0.017 0.0161
Schistosoma mansoni cgmp-dependent 35-cyclic phosphodiesterase 0.0026 0.0018 0.0008
Plasmodium falciparum serine repeat antigen 6 0.0051 0.0114 0.0765
Loa Loa (eye worm) hypothetical protein 0.0023 0.0006 0.0007
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0103 0.0318 0.067
Brugia malayi Endoplasmin precursor 0.0098 0.0299 0.0338
Echinococcus granulosus epidermal growth factor receptor 0.1204 0.4631 0.4626
Echinococcus granulosus histone acetyltransferase MYST2 0.0164 0.0559 0.055
Brugia malayi jmjC domain containing protein 0.0292 0.1058 0.1213
Trichomonas vaginalis fructose-bisphosphate aldolase, putative 0.0142 0.0471 0.0994
Toxoplasma gondii NAC domain-containing protein 0.0071 0.0194 0.1359
Schistosoma mansoni tyrosine kinase 0.0796 0.3034 0.3027
Schistosoma mansoni lamin 0.0026 0.0019 0.0009
Echinococcus granulosus phd:f box containing protein 0.0029 0.0028 0.0019
Mycobacterium tuberculosis Two component sensor histidine kinase DosT 0.0033 0.0045 0.0155
Plasmodium vivax serine-repeat antigen 3 (SERA) 0.0051 0.0114 0.0765
Loa Loa (eye worm) heterochromatin protein 1 0.0069 0.0187 0.0215
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0157 0.053 0.5506
Onchocerca volvulus 0.0026 0.0019 0.0026
Schistosoma mansoni SET domain protein 0.0034 0.0047 0.0038
Plasmodium vivax heat shock protein, putative 0.0372 0.1371 1
Echinococcus multilocularis endoplasmin 0.0092 0.0276 0.0267
Leishmania major heat shock protein 83-1 0.0098 0.0299 0.309
Loa Loa (eye worm) GTP-binding regulatory protein Gs alpha-S chain 0.0143 0.0477 0.055
Plasmodium falciparum dipeptidyl aminopeptidase 2 0.0051 0.0114 0.0765
Echinococcus granulosus heat shock protein 90 0.0084 0.0244 0.0235
Trypanosoma brucei dihydrolipoamide dehydrogenase, point mutation 0.0052 0.0119 0.1155
Loa Loa (eye worm) hypothetical protein 0.0038 0.0066 0.0076
Loa Loa (eye worm) hypothetical protein 0.0024 0.0009 0.0011
Trypanosoma cruzi cysteine peptidase C (CPC), putative 0.0265 0.0955 0.337
Echinococcus multilocularis lysine specific demethylase 5A 0.0108 0.0338 0.0328
Onchocerca volvulus 0.123 0.473 1
Loa Loa (eye worm) hypothetical protein 0.0059 0.0145 0.0167
Echinococcus granulosus chromobox protein 1 0.0069 0.0187 0.0177
Plasmodium falciparum heat shock protein 90, putative 0.0057 0.0139 0.0949
Schistosoma mansoni ubiquitously transcribed sex (X/Y) chromosome tetratricopeptide repeat protein-related 0.0029 0.0028 0.0019
Echinococcus multilocularis muscleblind protein 1 0.0151 0.0506 0.0497
Brugia malayi nuclear hormone receptor family member nhr-6 0.0038 0.0066 0.0069
Trypanosoma cruzi phosphatidylinositol kinase related protein, putative 0.0025 0.0014 0.0049
Mycobacterium ulcerans dihydrolipoamide dehydrogenase, LpdB 0.0052 0.0119 0.0452
Trichomonas vaginalis glucosylceramidase, putative 0.0524 0.1966 0.4154
Toxoplasma gondii cathepsin CPC1 0.0051 0.0114 0.0765
Trypanosoma cruzi cAMP specific phosphodiesterase, putative 0.0059 0.0147 0.052
Schistosoma mansoni SmCL2-like peptidase (C01 family) 0.0103 0.0318 0.0309
Loa Loa (eye worm) hypothetical protein 0.0038 0.0066 0.0076
Toxoplasma gondii heat shock protein HSP90 0.0098 0.0299 0.213
Echinococcus granulosus aldehyde dehydrogenase mitochondrial 0.0061 0.0156 0.0147
Brugia malayi Cathepsin L-like precursor 0.0052 0.012 0.0131
Loa Loa (eye worm) hypothetical protein 0.0024 0.0009 0.0011
Loa Loa (eye worm) hypothetical protein 0.0745 0.2833 0.3267
Brugia malayi Matrixin family protein 0.0035 0.0053 0.0053
Trypanosoma cruzi cysteine peptidase, putative 0.0157 0.053 0.187
Schistosoma mansoni microtubule-associated protein tau 0.1375 0.5299 0.5294
Loa Loa (eye worm) hypothetical protein 0.0448 0.1671 0.1927
Schistosoma mansoni mixed-lineage leukemia protein mll 0.0389 0.144 0.1431
Echinococcus multilocularis mixed lineage leukemia protein mll 0.0051 0.0113 0.0104
Trypanosoma cruzi cruzipain precursor, putative 0.0157 0.053 0.187
Trypanosoma cruzi transcription factor btf3, putative 0.0071 0.0194 0.0686
Trichomonas vaginalis conserved hypothetical protein 0.0027 0.0023 0.0046
Trypanosoma brucei heat shock protein, putative 0.0098 0.0299 0.3068
Giardia lamblia Cathepsin B precursor 0.0051 0.0114 0.0495
Brugia malayi jmjC domain containing protein 0.0029 0.0028 0.0025
Echinococcus granulosus insulin receptor 0.0719 0.2729 0.2722
Trichomonas vaginalis Clan CA, family C1, papain-like cysteine peptidase 0.0111 0.0349 0.0736
Loa Loa (eye worm) hypothetical protein 0.0082 0.0235 0.027
Echinococcus multilocularis Protein lozenge 0.0056 0.0136 0.0126
Echinococcus multilocularis raf serine:threonine protein kinase 0.0024 0.0011 0.0002
Trypanosoma brucei trypanothione reductase 0.015 0.0502 0.521
Schistosoma mansoni tyrosine kinase 0.1204 0.4631 0.4626
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0051 0.0114 0.0237
Trichomonas vaginalis cyclic nucleotide phosphodiesterase, putative 0.0059 0.0147 0.0309
Echinococcus multilocularis bromodomain adjacent to zinc finger domain 0.0258 0.0925 0.0917
Brugia malayi Steroid receptor seven-up type 2 0.0082 0.0235 0.0263
Onchocerca volvulus 0.0024 0.0009 0.0006
Schistosoma mansoni cathepsin F (C01 family) 0.0059 0.0145 0.0135
Trichomonas vaginalis glucosylceramidase, putative 0.0524 0.1966 0.4154
Plasmodium vivax dipeptidyl aminopeptidase 2, putative 0.0051 0.0114 0.0765
Mycobacterium tuberculosis NAD(P)H quinone reductase LpdA 0.038 0.1403 0.5628
Onchocerca volvulus Matrilysin homolog 0.0035 0.0053 0.0098
Brugia malayi Cathepsin L-like precursor 0.0111 0.0349 0.0396
Schistosoma mansoni hypothetical protein 0.0148 0.0495 0.0486
Trypanosoma cruzi ISWI complex protein 0.011 0.0345 0.1219
Brugia malayi Nuclear hormone receptor family member nhr-25 0.0082 0.0235 0.0263
Toxoplasma gondii PHD-finger domain-containing protein 0.0089 0.0264 0.1871
Echinococcus granulosus geminin 0.1741 0.6733 0.673
Brugia malayi cathepsin Z-like cysteine proteinase 0.0051 0.0114 0.0124
Brugia malayi cahepsin L-like non-peptiedase homolog 0.0051 0.0114 0.0124
Brugia malayi Matrixin family protein 0.0035 0.0053 0.0053
Onchocerca volvulus Matrilysin homolog 0.0078 0.022 0.0452
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0059 0.0145 0.0303
Brugia malayi photoreceptor-specific nuclear receptor 0.0082 0.0235 0.0263
Trichomonas vaginalis conserved hypothetical protein 0.0059 0.0147 0.0309
Trichomonas vaginalis heat shock protein, putative 0.0084 0.0244 0.0513
Schistosoma mansoni tar DNA-binding protein 0.0254 0.091 0.0902
Echinococcus multilocularis insulin receptor 0.0719 0.2729 0.2722
Trichomonas vaginalis glucosylceramidase, putative 0.0552 0.2076 0.4388
Trypanosoma brucei heat shock protein, putative 0.0098 0.0299 0.3068
Schistosoma mansoni cathepsin s 0.0052 0.012 0.0111
Entamoeba histolytica papain family cysteine protease domain containing protein 0.0051 0.0114 0.121
Toxoplasma gondii heat shock protein 75, putative 0.0065 0.017 0.1183
Loa Loa (eye worm) steroid hormone receptor 0.0082 0.0235 0.027
Schistosoma mansoni tyrosine kinase 0.0719 0.2729 0.2722
Loa Loa (eye worm) PHD-finger family protein 0.0089 0.0264 0.0305
Brugia malayi Nuclear hormone receptor family member nhr-3 0.0082 0.0235 0.0263
Giardia lamblia PHD finger protein 15 0.0089 0.0264 0.2196
Toxoplasma gondii preprocathepsin c precursor, putative 0.0051 0.0114 0.0765
Schistosoma mansoni nuclear receptor nhr-48 0.0038 0.0066 0.0057
Trypanosoma cruzi cysteine peptidase C (CPC), putative 0.0745 0.2833 1
Echinococcus multilocularis tumor protein p63 0.0341 0.1251 0.1243
Brugia malayi jmjC domain containing protein 0.0029 0.0028 0.0025
Echinococcus multilocularis ecdysone induced protein 78C 0.0082 0.0235 0.0225
Loa Loa (eye worm) hypothetical protein 0.0039 0.0067 0.0078
Trypanosoma brucei heat shock protein 90, putative 0.0098 0.0299 0.3068
Trichomonas vaginalis conserved hypothetical protein 0.0024 0.0009 0.0017
Toxoplasma gondii histone lysine acetyltransferase GCN5-B 0.006 0.015 0.1035
Loa Loa (eye worm) hypothetical protein 0.0045 0.0093 0.0108
Brugia malayi CXXC zinc finger family protein 0.0181 0.0623 0.0712
Echinococcus granulosus dihydrolipoamide dehydrogenase 0.0052 0.0119 0.0109
Echinococcus multilocularis cathepsin L cysteine protease 0.0111 0.0349 0.034
Mycobacterium tuberculosis Probable aldehyde dehydrogenase 0.0061 0.0156 0.0603
Brugia malayi Probable 3',5'-cyclic phosphodiesterase C32E12.2, putative 0.0026 0.0018 0.0013
Trichomonas vaginalis conserved hypothetical protein 0.0024 0.0009 0.0017
Brugia malayi Hsp90 protein 0.0065 0.017 0.0189
Loa Loa (eye worm) hypothetical protein 0.0043 0.0084 0.0097
Trichomonas vaginalis Clan CA, family C1, cathepsin L, S or H-like cysteine peptidase 0.0051 0.0114 0.0237
Trichomonas vaginalis glucosylceramidase, putative 0.0524 0.1966 0.4154
Schistosoma mansoni ataxia telangiectasia mutated (atm) 0.0025 0.0014 0.0004
Trichomonas vaginalis rod cGMP-specific 3,5-cyclic phosphodiesterase, putative 0.0059 0.0147 0.0309
Loa Loa (eye worm) hypothetical protein 0.0026 0.0017 0.002
Schistosoma mansoni nuclear hormone receptor 0.0082 0.0235 0.0225
Echinococcus multilocularis protein tyrosine kinase 0.0796 0.3034 0.3027
Echinococcus granulosus nuclear receptor subfamily 1 group D 0.0043 0.0084 0.0075
Brugia malayi Matrixin family protein 0.0035 0.0053 0.0053
Schistosoma mansoni methyl-cpg binding protein mbd 0.0122 0.0395 0.0386
Echinococcus granulosus nuclear receptor 2DBD gamma 0.0082 0.0235 0.0225
Schistosoma mansoni histone-lysine n-methyltransferase setb1 0.0281 0.1015 0.1006
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0103 0.0318 0.3266
Brugia malayi Immunoglobulin I-set domain containing protein 0.0483 0.1807 0.2079
Echinococcus granulosus 5'partial|histone lysine N methyltransferase SETDB2 0.0149 0.0498 0.0489
Echinococcus multilocularis cysteine protease 0.0111 0.0349 0.034
Entamoeba histolytica cysteine protease, putative 0.0051 0.0114 0.121
Trypanosoma cruzi cysteine protease, putative 0.0103 0.0318 0.1123
Brugia malayi Nuclear hormone receptor family member nhr-31 0.0082 0.0235 0.0263
Brugia malayi Nuclear hormone receptor family member nhr-40 0.0082 0.0235 0.0263
Leishmania major heat shock protein 83-1 0.0098 0.0299 0.309
Echinococcus multilocularis chromodomain helicase DNA binding protein 4 0.0035 0.0054 0.0044
Onchocerca volvulus 0.0038 0.0066 0.0126
Giardia lamblia Dipeptidyl-peptidase I precursor 0.0051 0.0114 0.0495
Trypanosoma brucei heat shock protein, putative 0.0098 0.0299 0.3068
Onchocerca volvulus 0.0034 0.0047 0.0086
Toxoplasma gondii histone lysine methyltransferase SET/SUV39 0.0158 0.0536 0.3866
Schistosoma mansoni tar DNA-binding protein 0.0254 0.091 0.0902
Trichomonas vaginalis chromodomain-helicase-DNA-binding protein, putative 0.0033 0.0046 0.0094
Giardia lamblia Cathepsin L precursor 0.0051 0.0114 0.0495
Trypanosoma cruzi heat shock protein 85, putative 0.0098 0.0299 0.1057
Leishmania major hypothetical protein, conserved 0.0029 0.0028 0.0228
Trichomonas vaginalis glutathione reductase, putative 0.0052 0.0119 0.0248
Brugia malayi cathepsin F-like cysteine proteinase 0.0052 0.012 0.0131
Echinococcus granulosus cpg binding protein 0.0205 0.0717 0.0709
Plasmodium falciparum dihydrolipoyl dehydrogenase, apicoplast 0.0052 0.0119 0.0802
Trichomonas vaginalis fructose-bisphosphate aldolase, putative 0.0142 0.0471 0.0994
Echinococcus granulosus defective proboscis extension response 0.0029 0.0028 0.0019
Echinococcus granulosus GPCR family 2 0.0082 0.0237 0.0228
Echinococcus granulosus lysine specific demethylase 5A 0.0132 0.0432 0.0423
Onchocerca volvulus Heterochromatin protein 1 homolog 0.0039 0.0067 0.0129
Trichomonas vaginalis cGMP-inhibited 3,5-cyclic phosphodiesterase, putative 0.0059 0.0147 0.0309
Schistosoma mansoni cathepsin B-like peptidase (C01 family) 0.0265 0.0955 0.0946
Toxoplasma gondii histone lysine demethylase JMJC1/KDM5D/JARID1D 0.0029 0.0028 0.0136
Loa Loa (eye worm) PHD-finger family protein 0.0024 0.0009 0.0011
Trypanosoma brucei heat shock protein, putative 0.0098 0.0299 0.3068
Brugia malayi 3'5'-cyclic nucleotide phosphodiesterase family protein 0.0026 0.0018 0.0013
Trypanosoma cruzi PAB1-binding protein , putative 0.0075 0.021 0.0742
Brugia malayi hypothetical protein 0.0074 0.0205 0.0229
Echinococcus granulosus Immunoglobulin 0.0029 0.0028 0.0019
Echinococcus multilocularis hepatocyte nuclear factor 4 alpha 0.0082 0.0235 0.0225
Echinococcus multilocularis Immunoglobulin 0.0029 0.0028 0.0019
Brugia malayi Ligand-binding domain of nuclear hormone receptor family protein 0.0082 0.0235 0.0263
Echinococcus multilocularis peregrin 0.011 0.0345 0.0336
Echinococcus granulosus bromodomain adjacent to zinc finger domain 0.0258 0.0925 0.0917
Brugia malayi Cathepsin L-like precursor 0.0059 0.0145 0.016
Trypanosoma cruzi cysteine peptidase, putative 0.0103 0.0318 0.1123
Brugia malayi Bromodomain containing protein 0.0552 0.2077 0.239
Loa Loa (eye worm) nuclear Hormone Receptor family member 0.0082 0.0235 0.027
Trypanosoma brucei heat shock protein 84, putative 0.0065 0.017 0.1704
Brugia malayi nuclear receptor subfamily 1, group D, member 1, putative 0.0038 0.0066 0.0069
Onchocerca volvulus 0.0111 0.0349 0.0726
Schistosoma mansoni RAR-like nuclear receptor 0.0082 0.0235 0.0225
Loa Loa (eye worm) hypothetical protein 0.0082 0.0235 0.027
Trypanosoma brucei inositol-1(or 4)-monophosphatase 1, putative 0.0074 0.0207 0.2091
Trichomonas vaginalis cyclic nucleotide phosphodiesterase, putative 0.0059 0.0147 0.0309
Plasmodium falciparum serine repeat antigen 9 0.0051 0.0114 0.0765
Giardia lamblia Fructose-bisphosphate aldolase 0.0142 0.0471 0.4539
Entamoeba histolytica hypothetical protein 0.0035 0.0053 0.0521
Echinococcus multilocularis geminin 0.1741 0.6733 0.673
Giardia lamblia Cathepsin L precursor 0.0051 0.0114 0.0495
Schistosoma mansoni zinc finger protein 0.0154 0.052 0.0511
Trypanosoma cruzi Ring finger domain/PHD-finger, putative 0.0024 0.0009 0.0033
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0111 0.0349 0.0736
Schistosoma mansoni tyrosine kinase 0.1186 0.4558 0.4553
Loa Loa (eye worm) hypothetical protein 0.0051 0.0114 0.0131
Schistosoma mansoni cathepsin F (C01 family) 0.0111 0.0349 0.034
Schistosoma mansoni heat shock protein 0.0098 0.0299 0.029
Plasmodium falciparum thioredoxin reductase 0.015 0.0502 0.3618
Toxoplasma gondii histone lysine acetyltransferase GCN5-A 0.006 0.015 0.1035
Entamoeba histolytica cysteine protease, putative 0.0111 0.0349 0.3869
Onchocerca volvulus 0.0181 0.0623 0.1306
Loa Loa (eye worm) hypothetical protein 0.003 0.0035 0.004
Loa Loa (eye worm) matrix metalloproteinase 0.0035 0.0053 0.0061
Echinococcus granulosus lamin dm0 0.0026 0.0019 0.0009
Echinococcus granulosus suppression of tumorigenicity 18 protein 0.0164 0.0559 0.055
Brugia malayi Latrophilin receptor protein 2 0.0082 0.0237 0.0266
Schistosoma mansoni cathepsin S (C01 family) 0.0051 0.0114 0.0104
Trichomonas vaginalis high-affinity cGMP-specific 3,5-cyclic phosphodiesterase, putative 0.0059 0.0147 0.0309
Trichomonas vaginalis high-affinity cGMP-specific 3,5-cyclic phosphodiesterase, putative 0.0059 0.0147 0.0309
Onchocerca volvulus 0.003 0.0035 0.006
Trichomonas vaginalis chromobox protein, putative 0.0069 0.0187 0.0392
Echinococcus granulosus SAM and MBT domain containing protein 0.0144 0.0481 0.0472
Onchocerca volvulus 0.0038 0.0066 0.0126
Brugia malayi Cathepsin L-like precursor 0.0059 0.0145 0.016
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0157 0.053 0.5506
Leishmania major acetoin dehydrogenase e3 component-like protein 0.0052 0.0119 0.1184
Entamoeba histolytica cysteine protease, putative 0.0103 0.0318 0.3517
Trypanosoma cruzi cysteine peptidase, putative 0.0052 0.012 0.0423
Loa Loa (eye worm) nuclear hormone receptor 0.0038 0.0066 0.0076
Echinococcus granulosus hepatocyte nuclear factor 4 alpha 0.0082 0.0235 0.0225
Toxoplasma gondii aldehyde dehydrogenase 0.0061 0.0156 0.1077
Plasmodium vivax serine-repeat antigen 2 (SERA) 0.0051 0.0114 0.0765
Entamoeba histolytica myo-inositol monophosphatase, putative 0.0074 0.0207 0.2265
Onchocerca volvulus Cathepsin L homolog 0.0051 0.0114 0.0227
Mycobacterium tuberculosis Probable dehydrogenase 0.0342 0.1253 0.5026
Toxoplasma gondii PHD-finger domain-containing protein 0.0029 0.0029 0.0147
Entamoeba histolytica heat shock protein 90, putative 0.0098 0.0299 0.3306
Echinococcus multilocularis nuclear receptor subfamily 1 group D 0.0043 0.0084 0.0075
Echinococcus multilocularis methyl CpG binding domain protein 2 0.0122 0.0395 0.0386
Entamoeba histolytica cysteine protease, putative 0.0103 0.0318 0.3517
Brugia malayi chromobox protein homolog 3 0.0039 0.0067 0.0071
Echinococcus multilocularis Jumonji, AT rich interactive domain 1B 0.0053 0.0122 0.0113
Trichomonas vaginalis fructose-bisphosphate aldolase, putative 0.0142 0.0471 0.0994
Echinococcus granulosus cathepsin b 0.0745 0.2833 0.2826
Echinococcus multilocularis SAM and MBT domain containing protein 0.0144 0.0481 0.0472
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0103 0.0318 0.067
Loa Loa (eye worm) papain family cysteine protease containing protein 0.0111 0.0349 0.0403
Giardia lamblia Cathepsin L precursor 0.0051 0.0114 0.0495
Echinococcus granulosus cadherin EGF LAG seven pass G type receptor 0.0082 0.0237 0.0228
Trichomonas vaginalis Clan CA, family C1, papain-like cysteine peptidase 0.0111 0.0349 0.0736
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0111 0.0349 0.0736
Echinococcus granulosus Basic leucine zipper bZIP transcription 0.0074 0.0205 0.0195
Schistosoma mansoni myst-related protein 0.0035 0.0053 0.0043
Schistosoma mansoni myst-related protein 0.0035 0.0053 0.0043
Trypanosoma brucei Heat shock protein 83, putative 0.0098 0.0299 0.3068
Trypanosoma cruzi dihydrolipoamide dehydrogenase, putative 0.0052 0.0119 0.0419
Echinococcus multilocularis phd:f box containing protein 0.0029 0.0028 0.0019
Trichomonas vaginalis glucosylceramidase, putative 0.0798 0.3041 0.6427
Toxoplasma gondii LsmAD domain-containing protein 0.0075 0.021 0.1476
Echinococcus multilocularis FTZ F1 nuclear receptor protein 0.0082 0.0235 0.0225
Loa Loa (eye worm) nuclear receptor NHR-67 0.0038 0.0066 0.0076
Trichomonas vaginalis calcium/calmodulin-dependent 3,5-cyclic nucleotide phosphodiesterase, putative 0.0059 0.0147 0.0309
Loa Loa (eye worm) nuclear hormone receptor family member nhr-1 0.0082 0.0235 0.027
Echinococcus granulosus guanine nucleotide binding protein Gs subunit 0.0143 0.0477 0.0468
Trichomonas vaginalis Clan CA, family C1, papain-like cysteine peptidase 0.0111 0.0349 0.0736
Schistosoma mansoni nuclear hormone receptor superfamily protein-related 0.0038 0.0066 0.0057
Echinococcus multilocularis aldehyde dehydrogenase, mitochondrial 0.0061 0.0156 0.0147
Echinococcus granulosus lysine specific demethylase 6a 0.0029 0.0028 0.0019
Schistosoma mansoni thyroid hormone receptor 0.0082 0.0235 0.0225
Loa Loa (eye worm) nuclear receptor nhr-7B 0.0038 0.0066 0.0076
Trichomonas vaginalis cyclic nucleotide phosphodiesterase, putative 0.0059 0.0147 0.0309
Loa Loa (eye worm) histone methyltransferase 0.0062 0.0157 0.0181
Schistosoma mansoni nuclear receptor 0.0038 0.0066 0.0057
Onchocerca volvulus Heat shock protein 75 kDa, mitochondrial homolog 0.0065 0.017 0.0347
Plasmodium vivax vivapain-2 0.0111 0.0349 0.2496
Echinococcus granulosus transcription factor btf3 0.0071 0.0194 0.0185
Onchocerca volvulus Steroid hormone receptor family member cnr14 homolog 0.0082 0.0235 0.0483
Brugia malayi Immunoglobulin I-set domain containing protein 0.0026 0.0017 0.0012
Loa Loa (eye worm) hypothetical protein 0.0035 0.0053 0.0061
Trypanosoma cruzi dihydrolipoamide dehydrogenase, putative 0.0052 0.0119 0.0419
Brugia malayi hypothetical protein 0.0024 0.0009 0.0004
Loa Loa (eye worm) acetyltransferase 0.0163 0.0555 0.064
Loa Loa (eye worm) intermediate filament tail domain-containing protein 0.0026 0.0019 0.0022
Loa Loa (eye worm) hypothetical protein 0.0024 0.0009 0.0011
Loa Loa (eye worm) transcription factor SMAD2 0.0242 0.0865 0.0997
Loa Loa (eye worm) hypothetical protein 0.0051 0.0114 0.0131
Trichomonas vaginalis conserved hypothetical protein 0.0041 0.0076 0.0157
Schistosoma mansoni phosphatidylserine receptor 0.0029 0.0028 0.0019
Loa Loa (eye worm) hypothetical protein 0.0038 0.0066 0.0076
Plasmodium vivax heat shock protein 86, putative 0.0098 0.0299 0.213
Entamoeba histolytica hypothetical protein 0.0074 0.0205 0.2237
Echinococcus granulosus raf serine:threonine protein kinase 0.0024 0.0011 0.0002
Brugia malayi Cathepsin L-like precursor 0.0111 0.0349 0.0396
Schistosoma mansoni chromodomain helicase DNA binding protein 0.0035 0.0054 0.0044
Mycobacterium ulcerans heat shock protein 90 0.0092 0.0276 0.1086
Loa Loa (eye worm) hypothetical protein 0.0029 0.0028 0.0032
Echinococcus multilocularis GPCR, family 2 0.0082 0.0237 0.0228
Onchocerca volvulus 0.0111 0.0349 0.0726
Loa Loa (eye worm) latrophilin receptor protein 2 0.0082 0.0237 0.0273
Loa Loa (eye worm) nuclear hormone receptor family member nhr-31 0.0082 0.0235 0.027
Entamoeba histolytica cysteine protease, putative 0.0103 0.0318 0.3517
Loa Loa (eye worm) hypothetical protein 0.0051 0.0114 0.0131
Loa Loa (eye worm) bromodomain containing protein 0.013 0.0426 0.0491
Loa Loa (eye worm) hypothetical protein 0.0111 0.0349 0.0403
Toxoplasma gondii WD domain, G-beta repeat-containing protein 0.0029 0.0029 0.0147
Loa Loa (eye worm) PHD-finger family protein 0.0148 0.0495 0.0571
Loa Loa (eye worm) hypothetical protein 0.0024 0.0009 0.0011
Trypanosoma brucei dihydrolipoyl dehydrogenase 0.0052 0.0119 0.1155
Trypanosoma cruzi heat shock protein 85, putative 0.0098 0.0299 0.1057
Entamoeba histolytica cysteine protease, putative 0.0051 0.0114 0.121
Plasmodium falciparum cysteine proteinase falcipain 3 0.0111 0.0349 0.2496
Mycobacterium leprae PROBABLE NADH DEHYDROGENASE NDH 0.0342 0.1253 0.5026
Leishmania major aldehyde dehydrogenase, mitochondrial precursor 0.0061 0.0156 0.1578
Echinococcus multilocularis cathepsin L cysteine protease 0.0111 0.0349 0.034
Trichomonas vaginalis calcium/calmodulin-dependent 3,5-cyclic nucleotide phosphodiesterase, putative 0.0059 0.0147 0.0309
Echinococcus granulosus PHD finger protein rhinoceros 0.0089 0.0264 0.0255
Trichomonas vaginalis fructose-bisphosphate aldolase, putative 0.0142 0.0471 0.0994
Brugia malayi hypothetical protein 0.0024 0.0009 0.0004
Echinococcus multilocularis Nuclear hormone receptor HR96 0.0038 0.0066 0.0057
Leishmania major heat shock protein 83-1 0.0098 0.0299 0.309
Brugia malayi beta-NAC-like protein 0.0071 0.0194 0.0217
Plasmodium falciparum thioredoxin reductase 0.0052 0.0119 0.0802
Schistosoma mansoni ecdysone-induced protein 78c (dr-78) 0.0043 0.0084 0.0075
Echinococcus granulosus Nuclear hormone receptor HR96 0.0038 0.0066 0.0057
Echinococcus granulosus Ataxin 2 N terminaldomain containing protein 0.0034 0.0048 0.0038
Loa Loa (eye worm) hypothetical protein 0.0082 0.0235 0.027
Echinococcus multilocularis retinoic acid receptor rxr beta a retinoic acid receptor rxr alpha a retinoic acid receptor rxr alpha 0.0038 0.0066 0.0057
Onchocerca volvulus 0.0427 0.1586 0.3343
Schistosoma mansoni SmCB2 peptidase (C01 family) 0.0745 0.2833 0.2826
Loa Loa (eye worm) pre-SET domain-containing protein family protein 0.1081 0.4148 0.4783
Schistosoma mansoni protein phosphatase 2C 0.0029 0.0028 0.0019
Brugia malayi AF-10 protein 0.0029 0.0029 0.0027
Mycobacterium tuberculosis Probable soluble pyridine nucleotide transhydrogenase SthA (STH) (NAD(P)(+) transhydrogenase [B-specific]) (nicotinamide nucleot 0.0052 0.0119 0.0452
Loa Loa (eye worm) ctsf protein 0.0111 0.0349 0.0403
Schistosoma mansoni steroid hormone receptor ad4bp 0.0082 0.0235 0.0225
Loa Loa (eye worm) hypothetical protein 0.0075 0.021 0.0243
Schistosoma mansoni jumonji/arid domain-containing protein 0.0132 0.0432 0.0423
Trichomonas vaginalis fructose-bisphosphate aldolase, putative 0.0142 0.0471 0.0994
Brugia malayi Matrixin family protein 0.0035 0.0053 0.0053
Onchocerca volvulus 0.0059 0.0145 0.0293
Schistosoma mansoni zinc finger protein 0.0038 0.0066 0.0057
Echinococcus multilocularis nuclear receptor 2DBD gamma 0.0038 0.0066 0.0057
Echinococcus granulosus Nuclear hormone receptor family member nhr 41 0.0082 0.0235 0.0225
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0111 0.0349 0.0736
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0051 0.0114 0.0237
Loa Loa (eye worm) mbt repeat family protein 0.0144 0.0481 0.0554
Loa Loa (eye worm) jmjC domain-containing protein 0.0029 0.0028 0.0032
Mycobacterium tuberculosis Inositol-1-monophosphatase SuhB 0.0067 0.0177 0.0686
Schistosoma mansoni aldehyde dehydrogenase 0.0061 0.0156 0.0147
Brugia malayi intermediate filament protein 0.0026 0.0019 0.0014
Trichomonas vaginalis heat shock protein, putative 0.0092 0.0276 0.058
Plasmodium falciparum serine repeat antigen 1 0.0051 0.0114 0.0765
Mycobacterium tuberculosis Probable reductase 0.0342 0.1253 0.5026
Trichomonas vaginalis Clan CA, family C1, cathepsin B-like cysteine peptidase 0.0051 0.0114 0.0237
Echinococcus multilocularis Ataxin 2, N terminal,domain containing protein 0.0034 0.0048 0.0038
Leishmania major heat shock protein 83-1 0.0098 0.0299 0.309
Trypanosoma cruzi cysteine peptidase, putative 0.0157 0.053 0.187
Schistosoma mansoni hypothetical protein 0.0029 0.0029 0.002
Echinococcus granulosus roundabout 2 0.0045 0.0093 0.0084
Brugia malayi jmjC domain containing protein 0.0132 0.0432 0.0491
Mycobacterium tuberculosis Putative ferredoxin reductase 0.0342 0.1253 0.5026
Echinococcus multilocularis Immunoglobulin 0.0029 0.0028 0.0019
Trichomonas vaginalis cGMP-dependent 3,5-cyclic phosphodiesterase, putative 0.0059 0.0147 0.0309
Echinococcus granulosus fetal alzheimer antigen falz 0.0172 0.0589 0.058
Echinococcus granulosus matrix metallopeptidase 7 M10 family 0.0127 0.0414 0.0405
Giardia lamblia Cysteine protease 0.0051 0.0114 0.0495
Echinococcus multilocularis epidermal growth factor receptor 0.1204 0.4631 0.4626
Plasmodium falciparum serine repeat antigen 4 0.0051 0.0114 0.0765
Trichomonas vaginalis Clan CA, family C1, papain-like cysteine peptidase 0.0111 0.0349 0.0736
Trichomonas vaginalis high-affinity cGMP-specific 3,5-cyclic phosphodiesterase, putative 0.0059 0.0147 0.0309
Schistosoma mansoni tar DNA-binding protein 0.0254 0.091 0.0902
Trypanosoma brucei PAB1-binding protein , putative 0.0075 0.021 0.2126
Entamoeba histolytica cysteine proteinase, putative 0.0111 0.0349 0.3869
Entamoeba histolytica hypothetical protein 0.0074 0.0205 0.2237
Brugia malayi Papain family cysteine protease containing protein 0.0103 0.0318 0.036
Loa Loa (eye worm) TK/EGFR protein kinase 0.2236 0.8672 1
Entamoeba histolytica acetyltransferase, GNAT family 0.0039 0.007 0.0716
Trypanosoma cruzi PAB1-binding protein , putative 0.0075 0.021 0.0742
Mycobacterium ulcerans hydrolase 0.0043 0.0082 0.0307
Plasmodium vivax dihydrolipoyl dehydrogenase, apicoplast, putative 0.0052 0.0119 0.0802
Plasmodium vivax thioredoxin reductase, putative 0.015 0.0502 0.3618
Trypanosoma brucei ISWI complex protein 0.011 0.0345 0.3553
Onchocerca volvulus Polycomb protein Sfmbt homolog 0.0144 0.0481 0.1004
Echinococcus multilocularis cathepsin b 0.0745 0.2833 0.2826
Schistosoma mansoni zinc finger protein 0.011 0.0345 0.0336
Toxoplasma gondii heat shock protein 90, putative 0.0098 0.0299 0.213
Echinococcus granulosus heat shock protein 75 kDa mitochondrial 0.0065 0.017 0.0161
Loa Loa (eye worm) hypothetical protein 0.0051 0.0114 0.0131
Schistosoma mansoni cathepsin B-like peptidase (C01 family) 0.0051 0.0114 0.0104
Trichomonas vaginalis cGMP-dependent 3,5-cyclic phosphodiesterase, putative 0.0026 0.0018 0.0035
Brugia malayi mbt repeat family protein 0.0144 0.0481 0.0547
Echinococcus granulosus histone acetyltransferase KAT2B 0.006 0.015 0.0141
Echinococcus granulosus cathepsin L 0.0103 0.0318 0.0309
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0111 0.0349 0.0736
Brugia malayi Cathepsin L-like precursor 0.0111 0.0349 0.0396
Trichomonas vaginalis conserved hypothetical protein 0.0027 0.0023 0.0046
Giardia lamblia Cathepsin B-like cysteine proteinase 3 precursor 0.0051 0.0114 0.0495
Brugia malayi steroid hormone receptor 0.0082 0.0235 0.0263
Trichomonas vaginalis cone cGMP-specific 3,5-cyclic phosphodiesterase, putative 0.0059 0.0147 0.0309
Loa Loa (eye worm) hypothetical protein 0.0082 0.0237 0.0273
Giardia lamblia Dipeptidyl-peptidase I precursor 0.0051 0.0114 0.0495
Trichomonas vaginalis rod cGMP-specific 3,5-cyclic phosphodiesterase, putative 0.0059 0.0147 0.0309
Brugia malayi acetyltransferase, GNAT family protein 0.0163 0.0555 0.0633
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0111 0.0349 0.0736
Schistosoma mansoni cpg binding protein 0.0181 0.0623 0.0615
Trypanosoma brucei cAMP-specific phosphodiesterase 0.0059 0.0147 0.146
Schistosoma mansoni histone-lysine n-methyltransferase suv9 0.017 0.058 0.0571
Echinococcus granulosus cAMP and cAMP inhibited cGMP 3'5' cyclic 0.0026 0.0018 0.0008
Brugia malayi hypothetical protein 0.0075 0.021 0.0235
Brugia malayi PHD-finger family protein 0.0024 0.0009 0.0004
Loa Loa (eye worm) hypothetical protein 0.0026 0.0018 0.0021
Trypanosoma cruzi cysteine peptidase, clan CA, family C1, cathepsin L-like, putative 0.0105 0.0325 0.1148
Mycobacterium ulcerans fructose-bisphosphate aldolase 0.0657 0.2487 1
Brugia malayi RNA binding protein 0.0254 0.091 0.1043
Entamoeba histolytica hypothetical protein 0.0074 0.0205 0.2237
Echinococcus granulosus Transcription factor JmjC domain containing protein 0.0292 0.1058 0.1049
Trichomonas vaginalis conserved hypothetical protein 0.0052 0.0119 0.0248
Plasmodium falciparum cysteine proteinase falcipain 2a 0.0111 0.0349 0.2496
Leishmania major hypothetical protein, conserved 0.0075 0.021 0.2151
Echinococcus multilocularis epidermal growth factor receptor 0.2236 0.8672 0.8671
Leishmania major trypanothione reductase 0.015 0.0502 0.5225
Brugia malayi cathepsin L-like cysteine proteinase, identical 0.0052 0.012 0.0131
Giardia lamblia Cathepsin B precursor 0.0265 0.0955 1
Echinococcus multilocularis FTZ F1 alpha 0.0082 0.0235 0.0225
Giardia lamblia Cysteine protease 0.0051 0.0114 0.0495
Trypanosoma cruzi heat shock protein 85, putative 0.0084 0.0244 0.0861
Leishmania major heat shock protein 83-1 0.0098 0.0299 0.309
Loa Loa (eye worm) hypothetical protein 0.0038 0.0066 0.0076
Loa Loa (eye worm) hypothetical protein 0.0043 0.0084 0.0097
Trichomonas vaginalis conserved hypothetical protein 0.0041 0.0076 0.0157
Schistosoma mansoni chromobox protein 0.0069 0.0187 0.0177
Echinococcus multilocularis nuclear receptor nhr 48 0.0038 0.0066 0.0057
Onchocerca volvulus 0.0111 0.0349 0.0726
Loa Loa (eye worm) nuclear hormone receptor family member nhr-41 0.0082 0.0235 0.027
Loa Loa (eye worm) hypothetical protein 0.0024 0.0009 0.0011
Entamoeba histolytica fructose-1,6-bisphosphate aldolase, putative 0.0142 0.0471 0.5247
Trichomonas vaginalis conserved hypothetical protein 0.0071 0.0194 0.0408
Loa Loa (eye worm) hypothetical protein 0.0151 0.0506 0.0583
Schistosoma mansoni mixed-lineage leukemia protein mll 0.0032 0.0039 0.003
Giardia lamblia Cathepsin B precursor 0.0051 0.0114 0.0495
Trypanosoma cruzi myo-inositol-1(or 4)-monophosphatase 1, putative 0.0074 0.0207 0.0731
Echinococcus granulosus cathepsin l1 0.0059 0.0145 0.0135
Toxoplasma gondii Hsp90 domain-containing protein 0.0372 0.1371 1
Toxoplasma gondii pyruvate dehydrogenase complex subunit PDH-E3II 0.0052 0.0119 0.0802
Echinococcus granulosus protein tyrosine kinase 0.0796 0.3034 0.3027
Schistosoma mansoni gcn5proteinral control of amino-acid synthesis 5-like 2 gcnl2 0.0163 0.0555 0.0546
Brugia malayi PHD-finger family protein 0.0024 0.0009 0.0004
Brugia malayi protein kinase C3,putative 0.0086 0.0253 0.0285
Echinococcus granulosus nuclear receptor nhr 48 0.0038 0.0066 0.0057
Echinococcus multilocularis roundabout 2 0.0045 0.0093 0.0084
Echinococcus granulosus zinc finger protein 0.0154 0.052 0.0511
Schistosoma mansoni hypothetical protein 0.0082 0.0237 0.0228
Echinococcus multilocularis histone lysine methyltransferase setb histone lysine methyltransferase eggless 0.0281 0.1015 0.1006
Trichomonas vaginalis chromodomain-helicase-DNA-binding protein, putative 0.0052 0.012 0.0251
Entamoeba histolytica heat shock protein 90, putative 0.0098 0.0299 0.3306
Brugia malayi Fibronectin type III domain containing protein 0.0029 0.0028 0.0025
Trichomonas vaginalis chromodomain-helicase-DNA-binding protein, putative 0.0052 0.012 0.0251
Trichomonas vaginalis Clan CA, family C1, cathepsin L or K-like cysteine peptidase 0.0111 0.0349 0.0736
Loa Loa (eye worm) DR-78 0.0038 0.0066 0.0076
Wolbachia endosymbiont of Brugia malayi heat shock protein 90 0.0092 0.0276 1
Plasmodium falciparum dipeptidyl aminopeptidase 1 0.0051 0.0114 0.0765
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0051 0.0114 0.0237
Leishmania major cysteine peptidase C (CPC),CPC cysteine peptidase, Clan CA, family C1, Cathepsin B-like 0.0265 0.0955 1
Trichomonas vaginalis conserved hypothetical protein 0.0071 0.0194 0.0408
Trichomonas vaginalis conserved hypothetical protein 0.0052 0.0119 0.0248
Loa Loa (eye worm) hypothetical protein 0.0043 0.0084 0.0097
Mycobacterium leprae possible inositol monophosphatase SubH (IMPase) (inositol-1-phosphatase) (I-1-Pase ). 0.0067 0.0177 0.0686
Echinococcus granulosus melanoma receptor tyrosine protein kinase 0.1204 0.4631 0.4626
Loa Loa (eye worm) nuclear hormone receptor family member nhr-14 0.0082 0.0235 0.027
Echinococcus multilocularis nuclear receptor subfamily 4 group A 0.0038 0.0066 0.0057
Plasmodium vivax dipeptidyl aminopeptidase 1, putative 0.0051 0.0114 0.0765
Trichomonas vaginalis Clan CA, family C1, papain-like cysteine peptidase 0.0111 0.0349 0.0736
Schistosoma mansoni tar DNA-binding protein 0.0254 0.091 0.0902
Schistosoma mansoni cathepsin B-like peptidase (C01 family) 0.0051 0.0114 0.0104
Trypanosoma cruzi JmjC domain, hydroxylase, putative 0.0029 0.0028 0.0099
Mycobacterium leprae PROBABLE CHAPERONE PROTEIN HTPG (HEAT SHOCK PROTEIN) (HSP90 FAMILY PROTEIN) (HIGH TEMPERATURE PROTEIN G) 0.0092 0.0276 0.1086
Schistosoma mansoni transcription factor btf3 0.0071 0.0194 0.0185
Plasmodium falciparum heat shock protein 90 0.0098 0.0299 0.213
Brugia malayi Bromodomain associated family protein 0.0024 0.0009 0.0004
Echinococcus multilocularis transcription factor btf3 0.0071 0.0194 0.0185
Brugia malayi latrophilin 2 splice variant baaae 0.0177 0.061 0.0697
Schistosoma mansoni Tr4/Tr2 (homologue) 0.0082 0.0235 0.0225
Echinococcus multilocularis thioredoxin glutathione reductase 0.015 0.0502 0.0493
Echinococcus granulosus methyl CpG binding domain protein 2 0.0122 0.0395 0.0386
Echinococcus multilocularis dnaJ subfamily B 0.2575 1 1
Brugia malayi Matrixin family protein 0.0085 0.0247 0.0278
Brugia malayi Pyridine nucleotide-disulphide oxidoreductase, dimerisation domain containing protein 0.0038 0.0065 0.0067
Echinococcus multilocularis Nuclear hormone receptor family member nhr 41 0.0082 0.0235 0.0225

Activities

Activity type Activity value Assay description Source Reference
IC50 (functional) 34.05 uM PubChem BioAssay. Discovery of small molecule inhibitors of the oncogenic and cytokinetic protein MgcRacGAP - Primary and Confirmatory Screens. (Class of assay: confirmatory) ChEMBL. No reference
Potency (functional) 1.4125 uM PubChem BioAssay. qHTS for Agonist of gsp, the Etiologic Mutation Responsible for Fibrous Dysplasia/McCune-Albright Syndrome: qHTS. (Class of assay: confirmatory) ChEMBL. No reference
Potency (functional) 8.9125 uM PubChem BioAssay. qHTS of GLP-1 Receptor Inverse Agonists (Inhibition Mode). (Class of assay: confirmatory) ChEMBL. No reference
Potency (functional) 14.1254 uM PUBCHEM_BIOASSAY: qHTS Assay for Inhibitors of JMJD2A-Tudor Domain. (Class of assay: confirmatory) [Related pubchem assays (depositor defined):AID504402] ChEMBL. No reference
Potency (functional) 19.9526 uM PUBCHEM_BIOASSAY: qHTS for Inhibitors of TGF-b: Cytotox Counterscreen. (Class of assay: confirmatory) [Related pubchem assays (depositor defined):AID588855, AID588860] ChEMBL. No reference
Potency (functional) 20.5962 uM PUBCHEM_BIOASSAY: Nrf2 qHTS screen for inhibitors. (Class of assay: confirmatory) [Related pubchem assays (depositor defined):AID493153, AID493163, AID504648] ChEMBL. No reference
Potency (functional) 31.6228 uM PubChem BioAssay. qHTS of Trypanosoma Brucei Inhibitors. (Class of assay: confirmatory) ChEMBL. No reference
Potency (functional) 32.6294 uM PUBCHEM_BIOASSAY: qHTS screen for small molecules that inhibit ELG1-dependent DNA repair in human embryonic kidney (HEK293T) cells expressing luciferase-tagged ELG1. (Class of assay: confirmatory) [Related pubchem assays (depositor defined):AID493107, AID493125] ChEMBL. No reference

Phenotypes

Whole-cell/tissue/organism interactions

Species name Source Reference Is orphan
Homo sapiens ChEMBL23

Many chemical entities in TDR Targets come from high-throughput screenings with whole cells or tissue samples, and not all assayed compounds have been tested against a single a single target protein, probably because they get ruled out during screening process. Even if these compounds may have not been of interest in the original screening, they may come as interesting leads for other screening assays. Furthermore, we may be able to propose drug-target associations using chemical similarities and network patterns.

Annotated phenotypes:

We have no manually annotated phenotypes for this drug. What does this mean? / Care to help?
In TDR Targets, information about phenotypes that are caused by drugs, or by genetic manipulation of cells (e.g. gene knockouts or knockdowns) is manually curated from the literature. These descriptions help to describe the potential of the target for drug development. If no information is available for this gene or if the information is incomplete, this may mean that i) the papers containing this information either appeared after the curation effort for this organism was carried out or they were inadvertently missed by curators; or that ii) the curation effort for this organism has not yet started.
 
In any case, if you have information about papers containing relevant validation data for this target, please log in using your TDR Targets username and password and send them to us using the corresponding form in this page (only visible to registered users) or contact us.

External resources for this compound

Bibliographic References

No literature references available for this target.

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