Detailed information for compound 1539294

Basic information

Technical information
  • Name: Unnamed compound
  • MW: 382.36 | Formula: C16H13F3N4O2S
  • H donors: 2 H acceptors: 4 LogP: 3.15 Rotable bonds: 4
    Rule of 5 violations (Lipinski): 1
  • SMILES: COc1ccc(c(c1)O)c1nc(N)nc(c1c1csc(n1)C)C(F)(F)F
  • InChi: 1S/C16H13F3N4O2S/c1-7-21-10(6-26-7)12-13(9-4-3-8(25-2)5-11(9)24)22-15(20)23-14(12)16(17,18)19/h3-6,24H,1-2H3,(H2,20,22,23)
  • InChiKey: XOCTVVVJFQYCGO-UHFFFAOYSA-N  


Substructure search Similarity search

Network

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Synonyms

No synonyms found for this compound

Targets

Known targets for this compound

No curated genes were found associated with this compound

Predicted pathogen targets for this compound

By orthology
No druggable targets predicted by orthology data
By sequence similarity to non orthologous known druggable targets
No druggable targets predicted by sequence similarity
Obtained from network model

Ranking Plot

Putative Targets List

Species Potential target Raw Global Species
Loa Loa (eye worm) GTP-binding regulatory protein Gs alpha-S chain 0.0045 0.0214 0.0314
Mycobacterium tuberculosis Probable zinc-type alcohol dehydrogenase AdhD (aldehyde reductase) 0.0041 0.0186 0.023
Echinococcus granulosus mothers against decapentaplegic 5 0.0017 0.0035 0.0047
Onchocerca volvulus Rap guanine nucleotide exchange factor 1 homolog 0.0185 0.1086 0.1404
Mycobacterium ulcerans Zn-dependent alcohol dehydrogenase, AdhX 0.0041 0.0186 0.023
Schistosoma mansoni rotamase 0.0033 0.0138 0.0274
Echinococcus multilocularis cathepsin L 0.0017 0.0038 0.0027
Trichomonas vaginalis PIKK family atypical protein kinase 0.0018 0.0044 0.0359
Echinococcus multilocularis Basic leucine zipper (bZIP) transcription 0.0036 0.0153 0.0142
Trypanosoma cruzi STE group serine/threonine-protein kinase, putative 0.0016 0.0029 0.0301
Trypanosoma brucei DNA polymerase kappa, putative 0.0013 0.0014 0.0131
Leishmania major oxidoreductase, putative 0.0041 0.0186 0.138
Trypanosoma brucei DNA polymerase kappa, putative 0.0013 0.0014 0.0131
Giardia lamblia Histone acetyltransferase GCN5 0.0041 0.0187 0.1278
Trypanosoma brucei apurinic/apyrimidinic endonuclease, putative 0.0019 0.0047 0.0476
Chlamydia trachomatis malonyl CoA-ACP transacylase 0.0041 0.019 0.1729
Loa Loa (eye worm) hypothetical protein 0.0016 0.0029 0.0042
Trypanosoma brucei DNA polymerase IV, putative 0.0019 0.0052 0.0521
Brugia malayi hypothetical protein 0.0036 0.0159 0.0206
Trypanosoma cruzi apurinic/apyrimidinic endonuclease 0.0019 0.0047 0.0494
Schistosoma mansoni hypothetical protein 0.0036 0.0153 0.0306
Brugia malayi Cathepsin L-like precursor 0.0033 0.0139 0.0181
Mycobacterium ulcerans multifunctional mycocerosic acid synthase membrane-associated Mas 0.0697 0.4279 0.705
Trypanosoma brucei DNA polymerase kappa, putative 0.0019 0.0052 0.0521
Mycobacterium leprae Probable multifunctional mycocerosic acid synthase membrane associated enzyme Mas 0.0697 0.4279 0.706
Loa Loa (eye worm) acyl carrier protein 0.0066 0.0345 0.0506
Loa Loa (eye worm) fibroinase 0.0033 0.0139 0.0204
Trichomonas vaginalis PIKK family atypical protein kinase 0.0018 0.0044 0.0359
Loa Loa (eye worm) hypothetical protein 0.0074 0.0394 0.0579
Trichomonas vaginalis chromodomain helicase DNA binding protein, putative 0.0013 0.0012 0.0088
Schistosoma mansoni phosphatidylinositol 3-and 4-kinase 0.0018 0.0044 0.0087
Mycobacterium leprae Probable polyketide synthase Pks1 0.0697 0.4279 0.706
Trichomonas vaginalis chromodomain helicase DNA binding protein, putative 0.0013 0.0012 0.0088
Plasmodium falciparum acyl carrier protein 0.0066 0.0345 0.3329
Plasmodium falciparum cysteine proteinase falcipain 2a 0.0033 0.0139 0.1095
Trypanosoma brucei DNA polymerase IV, putative 0.0019 0.0052 0.0521
Onchocerca volvulus 0.0613 0.3755 0.509
Trypanosoma cruzi ubiquitin carboxyl-terminal hydrolase, putative 0.0074 0.0394 0.4111
Mycobacterium ulcerans NADPH quinone oxidoreductase FadB4 0.0041 0.0186 0.023
Trichomonas vaginalis PIKK family atypical protein kinase 0.0018 0.0044 0.0359
Loa Loa (eye worm) follicle stimulating hormone receptor 0.0229 0.1361 0.2
Entamoeba histolytica cysteine proteinase, putative 0.0022 0.007 0.0902
Schistosoma mansoni smad1 5 8 and 0.0017 0.0035 0.007
Mycobacterium ulcerans polyketide synthase MbtC 0.0165 0.0959 0.1518
Onchocerca volvulus 0.0033 0.0139 0.0095
Trichomonas vaginalis PIKK family atypical protein kinase 0.0018 0.0044 0.0359
Loa Loa (eye worm) hypothetical protein 0.0022 0.007 0.0103
Mycobacterium tuberculosis Probable quinone reductase Qor (NADPH:quinone reductase) (zeta-crystallin homolog protein) 0.0041 0.0186 0.023
Mycobacterium tuberculosis Polyketide synthetase MbtC (polyketide synthase) 0.0225 0.1338 0.2151
Entamoeba histolytica deoxycytidyl transferase, putative 0.0019 0.0052 0.0376
Leishmania major beta-ketoacyl synthase family protein, putative,3-oxoacyl-acyl carrier protein synthase ii, putative 0.0165 0.0959 0.8189
Trypanosoma brucei oxidoreductase, putative 0.0041 0.0186 0.192
Echinococcus granulosus Basic leucine zipper bZIP transcription 0.0036 0.0153 0.0284
Echinococcus multilocularis isocitrate dehydrogenase 0.0032 0.0133 0.0122
Schistosoma mansoni single-minded 0.0016 0.0029 0.0058
Mycobacterium ulcerans hypothetical protein 0.0066 0.0345 0.0495
Trypanosoma cruzi cruzipain precursor, putative 0.0127 0.0723 0.7546
Entamoeba histolytica ubiquitin carboxyl-terminal hydrolase domain containing protein 0.0074 0.0394 1
Trichomonas vaginalis conserved hypothetical protein 0.0013 0.0012 0.0088
Leishmania major protein kinase, putative 0.002 0.0054 0.022
Trichomonas vaginalis DNA polymerase eta, putative 0.0019 0.0052 0.0429
Mycobacterium ulcerans non-ribosomal peptide synthetase MbtF 0.0066 0.0345 0.0495
Schistosoma mansoni SmCL2-like peptidase (C01 family) 0.0017 0.0038 0.0077
Trypanosoma brucei DNA polymerase kappa, putative 0.0019 0.0052 0.0521
Mycobacterium tuberculosis Probable polyketide synthase Pks9 0.0373 0.2258 0.3684
Mycobacterium ulcerans malonyl CoA-acyl carrier protein transacylase FabD 0.0041 0.019 0.0237
Trichomonas vaginalis Clan CA, family C1, papain-like cysteine peptidase 0.0033 0.0139 0.1181
Trypanosoma cruzi isocitrate dehydrogenase [NADP], mitochondrial precursor, putative 0.0032 0.0133 0.139
Mycobacterium ulcerans short-chain dehydrogenase 0.0045 0.0209 0.027
Trichomonas vaginalis PIKK family atypical protein kinase 0.0018 0.0044 0.0359
Echinococcus granulosus NADH dehydrogenase 0.0066 0.0345 0.0666
Loa Loa (eye worm) AMP-binding enzyme family protein 0.0613 0.3755 0.5517
Trichomonas vaginalis PIKK family atypical protein kinase 0.0018 0.0044 0.0359
Echinococcus granulosus intermediate filament protein 0.0027 0.0098 0.0172
Trypanosoma cruzi phosphatidylinositol kinase related protein, putative 0.0025 0.0086 0.0892
Trypanosoma cruzi NADP-dependent alcohol hydrogenase, putative 0.0041 0.0186 0.1935
Plasmodium falciparum malonyl CoA-acyl carrier protein transacylase 0.0041 0.019 0.1644
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0033 0.0139 0.1181
Trichomonas vaginalis adenylate cyclase, putative 0.0016 0.0029 0.0232
Trypanosoma brucei DNA polymerase kappa, putative 0.0019 0.0052 0.0521
Trypanosoma cruzi cysteine peptidase, putative 0.0127 0.0723 0.7546
Toxoplasma gondii FATC domain-containing protein 0.0025 0.0086 0.0196
Brugia malayi hypothetical protein 0.0036 0.0153 0.02
Entamoeba histolytica hypothetical protein 0.0036 0.0153 0.3235
Mycobacterium tuberculosis Polyketide synthase Pks2 0.0636 0.3899 0.6418
Trypanosoma cruzi acyl transferase-like protein, putative 0.0041 0.019 0.1978
Schistosoma mansoni cathepsin F (C01 family) 0.0033 0.0139 0.0278
Brugia malayi cytoplasmic intermediate filament protein 0.0014 0.002 0.0027
Loa Loa (eye worm) ctsf protein 0.0033 0.0139 0.0204
Loa Loa (eye worm) cysteine protease 0.0033 0.0139 0.0204
Echinococcus multilocularis isocitrate dehydrogenase 2 (NADP+) 0.0032 0.0133 0.0122
Giardia lamblia Endonuclease/Exonuclease/phosphatase 0.0019 0.0047 0.0034
Plasmodium vivax AP endonuclease (DNA-[apurinic or apyrimidinic site] lyase), putative 0.0019 0.0047 0.0494
Brugia malayi Cathepsin L-like precursor 0.0033 0.0139 0.0181
Leishmania major target of rapamycin (TOR) kinase 2, putative 0.0018 0.0044 0.013
Mycobacterium ulcerans acyl carrier protein 0.0066 0.0345 0.0495
Trypanosoma cruzi beta-ketoacyl synthase family protein, putative 0.0165 0.0959 1
Brugia malayi Intermediate filament tail domain containing protein 0.0027 0.0098 0.0127
Onchocerca volvulus Fatty acid synthase homolog 0.1182 0.731 1
Loa Loa (eye worm) exodeoxyribonuclease III family protein 0.0019 0.0047 0.007
Schistosoma mansoni TGF-beta signal transducer Smad2 0.0017 0.0035 0.007
Mycobacterium tuberculosis Probable polyketide synthase Pks8 0.0536 0.3279 0.5384
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0033 0.0139 0.1181
Brugia malayi MH2 domain containing protein 0.0245 0.1457 0.1895
Echinococcus granulosus cysteine protease 0.0017 0.0038 0.0053
Loa Loa (eye worm) hypothetical protein 0.0036 0.0159 0.0233
Brugia malayi Methyltransferase-like protein 4 0.0198 0.1164 0.1514
Trichomonas vaginalis Clan CA, family C1, cathepsin L or K-like cysteine peptidase 0.0033 0.0139 0.1181
Toxoplasma gondii type I fatty acid synthase, putative 0.0697 0.4279 1
Schistosoma mansoni transcription factor LCR-F1 0.0036 0.0153 0.0306
Echinococcus granulosus histone lysine N methyltransferase MLL3 0.0014 0.002 0.0016
Leishmania major DNA polymerase kappa, putative,DNA polymerase IV, putative 0.0019 0.0052 0.0202
Loa Loa (eye worm) hypothetical protein 0.0013 0.0012 0.0017
Trichomonas vaginalis Clan CA, family C1, cathepsin L or K-like cysteine peptidase 0.0033 0.0139 0.1181
Trypanosoma cruzi DNA polymerase kappa, putative 0.0019 0.0052 0.054
Echinococcus granulosus DNA apurinic or apyrimidinic site lyase 0.0019 0.0047 0.0072
Trichomonas vaginalis PIKK family atypical protein kinase 0.0018 0.0044 0.0359
Leishmania major oxidoreductase-like protein 0.0041 0.0186 0.138
Echinococcus multilocularis cathepsin l cysteine peptidase 0.0033 0.0139 0.0128
Echinococcus granulosus histone acetyltransferase KAT2B 0.0045 0.021 0.0397
Schistosoma mansoni ap endonuclease 0.0019 0.0047 0.0095
Trichomonas vaginalis adenylate and guanylate cyclases, putative 0.0016 0.0029 0.0232
Onchocerca volvulus 0.0033 0.0139 0.0095
Loa Loa (eye worm) Smad1 0.0017 0.0035 0.0052
Mycobacterium ulcerans phenyloxazoline synthase MbtB 0.0066 0.0345 0.0495
Trypanosoma cruzi cysteine proteinase, putative 0.0017 0.0038 0.04
Schistosoma mansoni microtubule-associated protein tau 0.0683 0.4192 0.8368
Echinococcus granulosus TGF beta signal transducer SmadC 0.0017 0.0035 0.0047
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0127 0.0723 0.7541
Giardia lamblia DINP protein human, muc B family 0.0019 0.0052 0.0073
Schistosoma mansoni cathepsin F (C01 family) 0.0033 0.0139 0.0278
Brugia malayi Alcohol dehydrogenase class III 0.0041 0.0186 0.0241
Brugia malayi follicle stimulating hormone receptor 0.0229 0.1361 0.177
Trichomonas vaginalis Clan CA, family C1, papain-like cysteine peptidase 0.0033 0.0139 0.1181
Echinococcus multilocularis terminal deoxycytidyl transferase rev1 0.0019 0.0052 0.004
Loa Loa (eye worm) transcription factor SMAD2 0.0245 0.1457 0.2141
Trichomonas vaginalis Clan CA, family C1, papain-like cysteine peptidase 0.0033 0.0139 0.1181
Echinococcus granulosus dnaJ subfamily B 0.0814 0.501 1
Echinococcus granulosus dna polymerase kappa 0.0019 0.0052 0.008
Onchocerca volvulus 0.0033 0.0139 0.0095
Wolbachia endosymbiont of Brugia malayi acyl carrier protein 0.0066 0.0345 0.3263
Leishmania major isocitrate dehydrogenase [NADP], mitochondrial precursor, putative 0.0032 0.0133 0.0919
Trypanosoma cruzi phosphatidylinositol 3-related kinase, putative 0.0018 0.0044 0.0454
Trichomonas vaginalis chromodomain-helicase-DNA-binding protein, putative 0.0013 0.0012 0.0088
Entamoeba histolytica NADP-dependent alcohol dehydrogenase, putative 0.0041 0.0186 0.4137
Trypanosoma brucei Acyl carrier protein, mitochondrial 0.0066 0.0345 0.3583
Schistosoma mansoni mixed-lineage leukemia protein mll 0.0014 0.002 0.004
Plasmodium vivax unspecified product 0.0017 0.0038 0.04
Leishmania major cathepsin L-like protease 0.0033 0.0139 0.0972
Leishmania major quinone oxidoreductase, putative 0.0041 0.0186 0.138
Leishmania major target of rapamycin kinase (TOR) kinase 3 0.0018 0.0044 0.013
Onchocerca volvulus 0.0052 0.0256 0.0257
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0127 0.0723 0.7541
Echinococcus multilocularis histone lysine N methyltransferase MLL3 0.0018 0.0042 0.003
Schistosoma mansoni cpg binding protein 0.006 0.0308 0.0615
Schistosoma mansoni 3-oxoacyl-[ACP] synthase 0.0165 0.0959 0.1913
Schistosoma mansoni ap endonuclease 0.0019 0.0047 0.0095
Brugia malayi MH1 domain containing protein 0.0017 0.0035 0.0046
Mycobacterium ulcerans quinone oxidoreductase 0.0041 0.0186 0.023
Entamoeba histolytica cysteine protease, putative 0.0033 0.0139 0.2834
Loa Loa (eye worm) hypothetical protein 0.0185 0.1086 0.1596
Trichomonas vaginalis chromodomain helicase DNA binding protein, putative 0.0013 0.0012 0.0088
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0127 0.0723 0.7541
Trypanosoma cruzi PAS-domain containing phosphoglycerate kinase, putative 0.0016 0.0029 0.0301
Toxoplasma gondii exonuclease III APE 0.0019 0.0047 0.0107
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0127 0.0723 0.7541
Giardia lamblia Methyltransferase like 2 0.0198 0.1164 1
Echinococcus granulosus mitochondrial trans 2 enoyl coenzyme A reductase 0.0041 0.0186 0.0348
Brugia malayi Cathepsin L-like cysteine proteinase 0.0022 0.007 0.0092
Plasmodium vivax vivapain-2 0.0033 0.0139 0.1452
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0017 0.0038 0.0314
Schistosoma mansoni hypothetical protein 0.0521 0.3182 0.6351
Mycobacterium leprae Probable fatty-acid-CoA synthetase FadD22 (fatty-acid-CoA ligase) (fatty-acid-CoA synthase) 0.0066 0.0345 0.0525
Trichomonas vaginalis chromodomain helicase DNA binding protein, putative 0.0013 0.0012 0.0088
Echinococcus granulosus ubiquitin specific protease 41 0.0074 0.0394 0.0765
Brugia malayi AMP-binding enzyme family protein 0.0202 0.119 0.1547
Echinococcus multilocularis dnaJ subfamily B 0.0814 0.501 0.5004
Plasmodium falciparum isocitrate dehydrogenase [NADP], mitochondrial 0.0032 0.0133 0.1031
Brugia malayi Smad1 0.0017 0.0035 0.0046
Entamoeba histolytica hypothetical protein 0.0025 0.0086 0.1326
Echinococcus multilocularis microtubule associated protein 2 0.0683 0.4192 0.4186
Brugia malayi Ubiquitin carboxyl-terminal hydrolase family protein 0.0074 0.0394 0.0512
Brugia malayi intermediate filament protein 0.0027 0.0098 0.0127
Mycobacterium ulcerans polyketide synthase Pks13 0.098 0.6049 1
Mycobacterium ulcerans fatty acid synthase Fas 0.0206 0.1217 0.1949
Loa Loa (eye worm) phosphopantetheine attachment site family protein 0.0066 0.0345 0.0506
Schistosoma mansoni hypothetical protein 0.0521 0.3182 0.6351
Mycobacterium tuberculosis Probable multifunctional mycocerosic acid synthase membrane-associated Mas 0.0697 0.4279 0.705
Trichomonas vaginalis chromodomain helicase DNA binding protein, putative 0.0013 0.0012 0.0088
Mycobacterium leprae Probable fatty-acid-CoA ligase FadD9 (fatty-acid-CoA synthetase) (fatty-acid-CoA synthase) 0.0066 0.0345 0.0525
Entamoeba histolytica cysteine proteinase, putative 0.0033 0.0139 0.2834
Trichomonas vaginalis conserved hypothetical protein 0.0016 0.0029 0.0232
Chlamydia trachomatis 3-oxoacyl-ACP synthase 0.0165 0.0959 1
Loa Loa (eye worm) phosphatidylinositol 3 0.0018 0.0044 0.0064
Trypanosoma brucei unspecified product 0.0013 0.0014 0.0131
Trypanosoma cruzi peptidyl-prolyl cis-trans isomerase 0.0032 0.0133 0.1384
Trypanosoma brucei ubiquitin carboxyl-terminal hydrolase, putative 0.0074 0.0394 0.4099
Trichomonas vaginalis PIKK family atypical protein kinase 0.0018 0.0044 0.0359
Trichomonas vaginalis PIKK family atypical protein kinase 0.0018 0.0044 0.0359
Trypanosoma brucei DNA polymerase kappa, putative 0.0019 0.0052 0.0521
Echinococcus granulosus aryl hydrocarbon receptor 0.0052 0.0258 0.0493
Onchocerca volvulus 0.0033 0.0139 0.0095
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0127 0.0723 0.7541
Trichomonas vaginalis conserved hypothetical protein 0.0016 0.0029 0.0232
Mycobacterium tuberculosis Hypothetical protein 0.0198 0.1164 0.1861
Loa Loa (eye worm) hypothetical protein 0.0367 0.2225 0.3268
Mycobacterium ulcerans quinone reductase Qor 0.0041 0.0186 0.023
Schistosoma mansoni methyltransferase-related 0.0198 0.1164 0.2324
Trypanosoma cruzi NADP-dependent alcohol hydrogenase, putative 0.0041 0.0186 0.1935
Mycobacterium tuberculosis P-hydroxybenzoyl-AMP ligase FadD22 0.0066 0.0345 0.0495
Plasmodium falciparum AP endonuclease (DNA-[apurinic or apyrimidinic site] lyase), putative 0.0019 0.0047 0.0098
Brugia malayi Cathepsin L-like precursor 0.0033 0.0139 0.0181
Loa Loa (eye worm) intermediate filament tail domain-containing protein 0.0027 0.0098 0.0144
Onchocerca volvulus Acyl carrier protein, mitochondrial homolog 0.0066 0.0345 0.0379
Loa Loa (eye worm) hypothetical protein 0.0027 0.0098 0.0144
Schistosoma mansoni [ACP] S-malonyltransferase 0.0041 0.019 0.0378
Loa Loa (eye worm) hypothetical protein 0.0026 0.0095 0.0139
Mycobacterium tuberculosis Acyl carrier protein (ACP) MbtL 0.0066 0.0345 0.0495
Onchocerca volvulus 0.1141 0.7055 0.9649
Trichomonas vaginalis PIKK family atypical protein kinase 0.0018 0.0044 0.0359
Trichomonas vaginalis Clan CA, family C1, papain-like cysteine peptidase 0.0033 0.0139 0.1181
Brugia malayi Beta-ketoacyl synthase, N-terminal domain containing protein 0.0165 0.0959 0.1247
Toxoplasma gondii acyl carrier protein ACP 0.0066 0.0345 0.0802
Schistosoma mansoni intermediate filament proteins 0.0027 0.0098 0.0195
Echinococcus multilocularis lamin 0.0027 0.0098 0.0086
Brugia malayi Cathepsin L-like precursor 0.0033 0.0139 0.0181
Mycobacterium ulcerans Type I modular polyketide synthase 0.0656 0.4024 0.6627
Echinococcus multilocularis mitochondrial trans 2 enoyl coenzyme A reductase 0.0041 0.0186 0.0174
Loa Loa (eye worm) aryl Hydrocarbon receptor Associated protein family member 0.0052 0.0258 0.0379
Mycobacterium ulcerans zinc-type alcohol dehydrogenase AdhD 0.0041 0.0186 0.023
Mycobacterium leprae PHENOLPTHIOCEROL SYNTHESIS TYPE-I POLYKETIDE SYNTHASE PPSD 0.0656 0.4024 0.6637
Schistosoma mansoni NADP-specific isocitrate dehydrogenase 0.0032 0.0133 0.0266
Mycobacterium tuberculosis Conserved hypothetical protein 0.0066 0.0345 0.0495
Schistosoma mansoni smad 0.0017 0.0035 0.007
Trypanosoma brucei DNA polymerase kappa, putative 0.0019 0.0052 0.0521
Leishmania major cathepsin L-like protease 0.0127 0.0723 0.6117
Trichomonas vaginalis conserved hypothetical protein 0.0013 0.0012 0.0088
Leishmania major cysteine peptidase A (CPA) 0.0033 0.0139 0.0972
Echinococcus granulosus histone acetyltransferase KAT2B 0.0148 0.0853 0.1683
Trichomonas vaginalis PIKK family atypical protein kinase 0.0018 0.0044 0.0359
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0033 0.0139 0.1181
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0033 0.0139 0.1181
Mycobacterium tuberculosis Probable fatty acid synthase Fas (fatty acid synthetase) 0.0206 0.1217 0.1949
Schistosoma mansoni smad1 5 8 and 0.0017 0.0035 0.007
Loa Loa (eye worm) hypothetical protein 0.0101 0.0559 0.0821
Mycobacterium leprae Probable oxidireductase 0.0041 0.0186 0.026
Brugia malayi Phosphatidylinositol 3- and 4-kinase family protein 0.0018 0.0044 0.0057
Leishmania major cathepsin L-like protease 0.0127 0.0723 0.6117
Loa Loa (eye worm) histone methyltransferase 0.0018 0.0042 0.0061
Loa Loa (eye worm) acetyltransferase 0.0152 0.0879 0.1292
Mycobacterium ulcerans phenolpthiocerol synthesis type-I polyketide synthase PpsD 0.0656 0.4024 0.6627
Echinococcus granulosus cathepsin l cysteine peptidase 0.0033 0.0139 0.0255
Entamoeba histolytica peptidyl-prolyl cis-trans isomerase, putative 0.0032 0.0133 0.2651
Mycobacterium tuberculosis Possible dehydrogenase 0.0041 0.0186 0.023
Trichomonas vaginalis PIKK family atypical protein kinase 0.0018 0.0044 0.0359
Brugia malayi GTP-binding regulatory protein Gs alpha-S chain, putative 0.0045 0.0214 0.0278
Mycobacterium tuberculosis Phenolpthiocerol synthesis type-I polyketide synthase PpsE 0.0101 0.0559 0.0853
Mycobacterium leprae Probable S-nitrosomycothiol reductase MscR 0.0041 0.0186 0.026
Schistosoma mansoni [ACP] S-malonyltransferase 0.0041 0.019 0.0378
Trichomonas vaginalis adenylate cyclase, type VII, putative 0.0016 0.0029 0.0232
Trypanosoma cruzi oxidoreductase, putative 0.0041 0.0186 0.1935
Trichomonas vaginalis conserved hypothetical protein 0.0013 0.0012 0.0088
Brugia malayi oxidoreductase, short chain dehydrogenase/reductase family protein 0.0066 0.0345 0.0448
Echinococcus multilocularis histone lysine N methyltransferase MLL3 0.0014 0.002 0.0008
Brugia malayi oxidoreductase, zinc-binding dehydrogenase family protein 0.0041 0.0186 0.0241
Trichomonas vaginalis DNA polymerase IV / kappa, putative 0.0019 0.0052 0.0429
Trichomonas vaginalis alcohol dehydrogenase, putative 0.0041 0.0186 0.158
Leishmania major NADP-dependent alcohol dehydrogenase, putative 0.0041 0.0186 0.138
Schistosoma mansoni alcohol dehydrogenase 0.0041 0.0186 0.037
Trypanosoma brucei DNA polymerase kappa, putative 0.0019 0.0052 0.0521
Mycobacterium tuberculosis Probable oxidoreductase 0.0041 0.0186 0.023
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0127 0.0723 0.7541
Brugia malayi oxidoreductase, zinc-binding dehydrogenase family protein 0.1243 0.7689 1
Trypanosoma cruzi Acyl carrier protein, mitochondrial, putative 0.0066 0.0345 0.3596
Echinococcus multilocularis cathepsin L cysteine protease 0.0033 0.0139 0.0128
Echinococcus granulosus cathepsin l1 0.0033 0.0139 0.0255
Mycobacterium tuberculosis Polyketide synthase Pks13 0.098 0.6049 1
Mycobacterium ulcerans oxidoreductase 0.0041 0.0186 0.023
Trichomonas vaginalis PIKK family atypical protein kinase 0.0018 0.0044 0.0359
Entamoeba histolytica FKBP-rapamycin associated protein (FRAP), putative 0.0018 0.0044 0.0146
Mycobacterium leprae PHENOLPTHIOCEROL SYNTHESIS TYPE-I POLYKETIDE SYNTHASE PPSB 0.0528 0.3225 0.5309
Schistosoma mansoni ubiquitin-specific peptidase 2 (C19 family) 0.0074 0.0394 0.0787
Onchocerca volvulus 0.007 0.0369 0.0412
Mycobacterium ulcerans dehydrogenase 0.0041 0.0186 0.023
Mycobacterium ulcerans non-ribosomal peptide synthetase MbtE 0.0066 0.0345 0.0495
Schistosoma mansoni Smad4 0.0017 0.0035 0.007
Mycobacterium tuberculosis Probable polyketide synthase Pks7 0.0697 0.4279 0.705
Trypanosoma brucei peptidyl-prolyl cis-trans isomerase/rotamase, putative 0.0032 0.0133 0.1367
Plasmodium falciparum 3-oxoacyl-acyl-carrier protein synthase I/II 0.0165 0.0959 1
Trypanosoma cruzi phosphatidylinositol 3-related kinase, putative 0.0018 0.0044 0.0454
Loa Loa (eye worm) phosphatidylinositol 3 0.0018 0.0044 0.0064
Mycobacterium tuberculosis Phenolpthiocerol synthesis type-I polyketide synthase PpsB 0.0101 0.0559 0.0853
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0033 0.0139 0.1181
Schistosoma mansoni lamin 0.0027 0.0098 0.0195
Echinococcus granulosus 3 oxoacyl acyl carrier protein synthase 0.0165 0.0959 0.1895
Leishmania major cathepsin L-like protease 0.0033 0.0139 0.0972
Mycobacterium ulcerans NADP-dependent oxidoreductase 0.0041 0.0186 0.023
Loa Loa (eye worm) Pin1-type peptidyl-prolyl cis-trans isomerase 0.0033 0.0138 0.0202
Brugia malayi acyl carrier protein, mitochondrial precursor, putative 0.0066 0.0345 0.0448
Mycobacterium ulcerans Type I modular polyketide synthase 0.0656 0.4024 0.6627
Loa Loa (eye worm) MH1 domain-containing protein 0.0017 0.0035 0.0052
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0017 0.0038 0.0314
Loa Loa (eye worm) helix-loop-helix DNA-binding domain-containing protein 0.0037 0.016 0.0235
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0017 0.0038 0.0382
Mycobacterium ulcerans oxidoreductase 0.0041 0.0186 0.023
Mycobacterium ulcerans thioesterase 0.0547 0.3342 0.549
Trypanosoma cruzi cysteine peptidase, putative 0.0127 0.0723 0.7546
Chlamydia trachomatis acyl carrier protein 0.0066 0.0345 0.3397
Plasmodium vivax isocitrate dehydrogenase [NADP], mitochondrial, putative 0.0032 0.0133 0.139
Loa Loa (eye worm) ImpB/MucB/SamB family protein 0.0019 0.0052 0.0076
Schistosoma mansoni cpg binding protein 0.0057 0.0288 0.0575
Leishmania major DNA polymerase eta, putative 0.0019 0.0052 0.0202
Schistosoma mansoni ubiquitin-specific peptidase 8 (C19 family) 0.0074 0.0394 0.0787
Trichomonas vaginalis PIKK family atypical protein kinase 0.0018 0.0044 0.0359
Leishmania major hypothetical protein, conserved 0.0198 0.1164 1
Brugia malayi ADP-specific Phosphofructokinase/Glucokinase conserved region family protein 0.0041 0.019 0.0247
Trypanosoma brucei DNA polymerase eta, putative 0.0019 0.0052 0.0521
Echinococcus granulosus acyl carrier protein mitochondrial 0.0066 0.0345 0.0666
Mycobacterium leprae PROBABLE FATTY ACID SYNTHASE FAS (FATTY ACID SYNTHETASE) 0.0206 0.1217 0.1974
Schistosoma mansoni terminal deoxycytidyl transferase 0.0019 0.0052 0.0103
Loa Loa (eye worm) papain family cysteine protease containing protein 0.0033 0.0139 0.0204
Echinococcus granulosus histone lysine N methyltransferase MLL3 0.0018 0.0042 0.006
Echinococcus granulosus cpg binding protein 0.006 0.0308 0.0593
Trypanosoma cruzi beta-ketoacyl synthase family protein, putative 0.0165 0.0959 1
Loa Loa (eye worm) alcohol dehydrogenase class III 0.0041 0.0186 0.0273
Mycobacterium leprae PROBABLE THIOESTERASE TESA 0.0547 0.3342 0.5504
Loa Loa (eye worm) Papain cysteine protease/cathepsin propeptide inhibitor-containing protein 0.0033 0.0139 0.0204
Mycobacterium tuberculosis Probable polyketide synthase Pks15 0.0265 0.1586 0.2565
Loa Loa (eye worm) hypothetical protein 0.0041 0.0186 0.0273
Loa Loa (eye worm) hypothetical protein 0.0012 0.0009 0.0013
Trichomonas vaginalis conserved hypothetical protein 0.0198 0.1164 1
Trypanosoma cruzi cysteine protease, putative 0.0017 0.0038 0.04
Onchocerca volvulus 0.0057 0.0288 0.03
Schistosoma mansoni ataxia telangiectasia mutated (atm)-related 0.0018 0.0044 0.0087
Echinococcus multilocularis guanine nucleotide binding protein G(s) subunit 0.0045 0.0214 0.0202
Trypanosoma cruzi oxidoreductase, putative 0.0041 0.0186 0.1935
Loa Loa (eye worm) beta-ketoacyl synthase domain-containing protein 0.0165 0.0959 0.1408
Onchocerca volvulus 0.0033 0.0139 0.0095
Plasmodium falciparum cysteine proteinase falcipain 3 0.0033 0.0139 0.1095
Echinococcus multilocularis expressed protein 0.0033 0.0138 0.0126
Wolbachia endosymbiont of Brugia malayi NADPH:quinone reductase 0.0041 0.0186 0.1516
Plasmodium vivax malonyl CoA-acyl carrier protein transacylase precursor, putative 0.0041 0.019 0.1978
Trichomonas vaginalis Clan CA, family C1, papain-like cysteine peptidase 0.0033 0.0139 0.1181
Echinococcus granulosus FKBP12 rapamycin complex associated protein 0.0018 0.0044 0.0064
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0127 0.0723 0.7541
Brugia malayi Phosphatidylinositol 3- and 4-kinase family protein 0.0018 0.0044 0.0057
Mycobacterium tuberculosis Conserved hypothetical protein 0.0019 0.0052 0.0007
Echinococcus granulosus expressed protein 0.0033 0.0138 0.0252
Trichomonas vaginalis PIKK family atypical protein kinase 0.0018 0.0044 0.0359
Mycobacterium ulcerans zinc-dependent alcohol dehydrogenase 0.0041 0.0186 0.023
Trypanosoma brucei DNA polymerase kappa, putative 0.0019 0.0052 0.0521
Trichomonas vaginalis Clan CA, family C1, papain-like cysteine peptidase 0.0033 0.0139 0.1181
Trypanosoma cruzi cysteine peptidase, putative 0.0017 0.0038 0.04
Mycobacterium ulcerans polyketide synthase MbtD 0.0202 0.119 0.1903
Mycobacterium tuberculosis Possible dehydrogenase 0.0041 0.0186 0.023
Toxoplasma gondii AMP-binding enzyme domain-containing protein 0.0331 0.2 0.4672
Brugia malayi Cathepsin L-like precursor 0.0022 0.007 0.0092
Mycobacterium ulcerans zinc-containing alcohol dehydrogenase NAD dependent AdhB 0.0041 0.0186 0.023
Plasmodium vivax 3-oxoacyl-[acyl-carrier-protein] synthase i/ii, putative 0.0165 0.0959 1
Plasmodium falciparum histone acetyltransferase GCN5 0.0041 0.0187 0.1614
Echinococcus granulosus serine protein kinase ATM 0.0025 0.0086 0.0148
Brugia malayi Cathepsin L-like precursor 0.0022 0.007 0.0092
Echinococcus multilocularis cathepsin l cysteine peptidase 0.0033 0.0139 0.0128
Loa Loa (eye worm) hypothetical protein 0.0052 0.0256 0.0376
Loa Loa (eye worm) hypothetical protein 0.0012 0.0009 0.0013
Trichomonas vaginalis PIKK family atypical protein kinase 0.0018 0.0044 0.0359
Echinococcus multilocularis AMP dependent ligase 0.0066 0.0345 0.0333
Trichomonas vaginalis conserved hypothetical protein 0.0074 0.0394 0.3374
Brugia malayi N-terminal motif family protein 0.0185 0.1086 0.1413
Mycobacterium tuberculosis Probable polyketide synthase Pks17 0.016 0.0931 0.1473
Loa Loa (eye worm) hypothetical protein 0.0036 0.0159 0.0233
Echinococcus multilocularis DNA (apurinic or apyrimidinic site) lyase 0.0019 0.0047 0.0036
Brugia malayi Beta-ketoacyl synthase, N-terminal domain containing protein 0.0656 0.4024 0.5234
Mycobacterium ulcerans acyl-CoA synthetase 0.0066 0.0345 0.0495
Brugia malayi Papain family cysteine protease containing protein 0.0033 0.0139 0.0181
Entamoeba histolytica hypothetical protein 0.0036 0.0153 0.3235
Trypanosoma brucei DNA polymerase kappa, putative 0.0019 0.0052 0.0521
Leishmania major DNA polymerase kappa, putative 0.0019 0.0052 0.0202
Loa Loa (eye worm) CXXC zinc finger family protein 0.0057 0.0288 0.0423
Echinococcus granulosus geminin 0.0521 0.3182 0.6342
Brugia malayi Papain family cysteine protease containing protein 0.0017 0.0038 0.005
Echinococcus granulosus Peptidase C19 ubiquitin carboxyl terminal hydrolase 2 0.0074 0.0394 0.0765
Echinococcus multilocularis mothers against decapentaplegic 5 0.0017 0.0035 0.0024
Mycobacterium leprae conserved hypothetical protein 0.0066 0.0345 0.0525
Toxoplasma gondii peptidylprolyl isomerase 0.0032 0.0133 0.0306
Mycobacterium ulcerans quinone oxidoreductase 0.0041 0.0186 0.023
Brugia malayi aryl hydrocarbon receptor nuclear translocator protein, putative 0.0037 0.016 0.0208
Trichomonas vaginalis PIKK family atypical protein kinase 0.0018 0.0044 0.0359
Mycobacterium tuberculosis Phenolpthiocerol synthesis type-I polyketide synthase PpsC 0.0656 0.4024 0.6627
Entamoeba histolytica phosphatidylinositol3-kinaseTor2, putative 0.0018 0.0044 0.0146
Mycobacterium ulcerans acyl carrier protein 0.0066 0.0345 0.0495
Mycobacterium ulcerans non-ribosomal peptide synthetase 0.0066 0.0345 0.0495
Toxoplasma gondii acyl transferase domain-containing protein 0.0041 0.019 0.0439
Echinococcus multilocularis dna polymerase kappa 0.0019 0.0052 0.004
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0033 0.0139 0.1181
Brugia malayi CXXC zinc finger family protein 0.0057 0.0288 0.0374
Mycobacterium leprae Polyketide synthase Pks13 0.098 0.6049 1
Mycobacterium ulcerans fatty-acid-CoA ligase FadD9 0.0066 0.0345 0.0495
Echinococcus granulosus ubiquitin carboxyl terminal hydrolase 8 0.0074 0.0394 0.0765
Trichomonas vaginalis PIKK family atypical protein kinase 0.0018 0.0044 0.0359
Brugia malayi AMP-binding enzyme family protein 0.0613 0.3755 0.4884
Echinococcus granulosus cathepsin l1 0.0022 0.007 0.0118
Trypanosoma brucei phosphatidylinositol kinase related protein, putative 0.0025 0.0086 0.0875
Trypanosoma cruzi target of rapamycin kinase 3 0.0018 0.0044 0.0454
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0127 0.0723 0.7541
Mycobacterium ulcerans polyketide synthase Pks9 0.0434 0.2638 0.4317
Mycobacterium ulcerans NADP-dependent alcohol dehydrogenase AdhC 0.0041 0.0186 0.023
Echinococcus multilocularis Aryl hydrocarbon receptor nuclear 0.0016 0.003 0.0019
Leishmania major apurinic/apyrimidinic endonuclease-redox protein 0.0019 0.0047 0.0163
Entamoeba histolytica NADP-dependent alcohol dehydrogenase 0.0041 0.0186 0.4137
Trypanosoma cruzi DNA polymerase kappa, putative 0.0019 0.0052 0.054
Echinococcus multilocularis dna polymerase eta 0.0019 0.0052 0.004
Entamoeba histolytica NADP-dependent alcohol dehydrogenase, putative 0.0041 0.0186 0.4137
Leishmania major phosphatidylinositol 3-related kinase, putative 0.0018 0.0044 0.013
Trypanosoma brucei DNA polymerase kappa, putative 0.0019 0.0052 0.0521
Brugia malayi Papain family cysteine protease containing protein 0.0017 0.0038 0.005
Brugia malayi oxidoreductase, zinc-binding dehydrogenase family protein 0.0041 0.0186 0.0241
Trichomonas vaginalis PIKK family atypical protein kinase 0.0018 0.0044 0.0359
Trichomonas vaginalis conserved hypothetical protein 0.0013 0.0012 0.0088
Schistosoma mansoni aryl hydrocarbon receptor 0.0016 0.003 0.0061
Echinococcus multilocularis mixed lineage leukemia protein mll 0.0014 0.002 0.0008
Toxoplasma gondii type I fatty acid synthase, putative 0.0467 0.2845 0.6648
Entamoeba histolytica hypothetical protein 0.0036 0.0153 0.3235
Toxoplasma gondii 3-oxoacyl-acyl-carrier protein synthase I/II, putative 0.0165 0.0959 0.2237
Echinococcus granulosus guanine nucleotide binding protein Gs subunit 0.0045 0.0214 0.0404
Leishmania major hypothetical protein, conserved 0.0041 0.019 0.1416
Trypanosoma cruzi STE/STE11 serine/threonine-protein kinase, putative 0.0016 0.0029 0.0301
Trypanosoma brucei phosphatidylinositol 3-related kinase, putative 0.0018 0.0044 0.0436
Trypanosoma cruzi nuclear receptor binding factor, putative 0.0041 0.0186 0.1935
Mycobacterium tuberculosis S-nitrosomycothiol reductase MscR 0.0041 0.0186 0.023
Echinococcus multilocularis TGF beta signal transducer SmadC 0.0017 0.0035 0.0024
Trichomonas vaginalis PIKK family atypical protein kinase 0.0018 0.0044 0.0359
Leishmania major d-xylulose reductase, putative 0.0041 0.0186 0.138
Brugia malayi aryl hydrocarbon receptor AHR-1 0.0036 0.0159 0.0206
Trichomonas vaginalis Clan CA, family C1, papain-like cysteine peptidase 0.0033 0.0139 0.1181
Echinococcus granulosus guanine nucleotide binding protein Gs subunit 0.0045 0.0214 0.0404
Mycobacterium tuberculosis Probable polyketide beta-ketoacyl synthase Pks4 0.0101 0.0559 0.0853
Loa Loa (eye worm) hypothetical protein 0.0101 0.0559 0.0821
Echinococcus granulosus cathepsin L cysteine proteinase 0.0033 0.0139 0.0255
Trypanosoma brucei phosphatidylinositol 4-kinase, putative 0.0018 0.0044 0.0436
Trypanosoma brucei DNA polymerase kappa, putative 0.0013 0.0014 0.0131
Trichomonas vaginalis PIKK family atypical protein kinase 0.0018 0.0044 0.0359
Trypanosoma brucei phosphatidylinositol 3-kinase, putative 0.0018 0.0044 0.0436
Leishmania major zinc binding dehydrogenase-like protein 0.0041 0.0186 0.138
Echinococcus granulosus phosphatidylinositol 3 and 4 kinase 0.0018 0.0044 0.0064
Trichomonas vaginalis Clan CA, family C19, ubiquitin hydrolase-like cysteine peptidase 0.0074 0.0394 0.3374
Trypanosoma cruzi STE/STE11 serine/threonine-protein kinase, putative 0.0016 0.0029 0.0301
Trichomonas vaginalis conserved hypothetical protein 0.0016 0.0029 0.0232
Trypanosoma brucei DNA polymerase kappa, putative 0.0019 0.0052 0.0521
Mycobacterium tuberculosis Probable alcohol dehydrogenase Adh 0.0041 0.0186 0.023
Toxoplasma gondii cathepsin CPL 0.0033 0.0139 0.0321
Trypanosoma cruzi cysteine peptidase, putative 0.0127 0.0723 0.7546
Mycobacterium ulcerans phenolpthiocerol synthesis type-I polyketide synthase PpsA 0.0528 0.3225 0.5294
Schistosoma mansoni Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) 0.0045 0.0214 0.0427
Trypanosoma brucei Phosphatidylinositol 3-kinase tor1 0.0018 0.0044 0.0436
Plasmodium vivax histone acetyltransferase GCN5, putative 0.0045 0.021 0.2191
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0127 0.0723 0.7541
Brugia malayi Isocitrate dehydrogenase 0.0032 0.0133 0.0173
Entamoeba histolytica cysteine proteinase, putative 0.0033 0.0139 0.2834
Trypanosoma brucei unspecified product 0.0019 0.0052 0.0521
Brugia malayi hypothetical protein 0.0052 0.0256 0.0333
Mycobacterium ulcerans phenolpthiocerol synthesis type-I polyketide synthase PpsE 0.0434 0.2638 0.4317
Echinococcus multilocularis cysteine protease 0.0033 0.0139 0.0128
Trypanosoma cruzi DNA polymerase eta, putative 0.0019 0.0052 0.054
Echinococcus multilocularis Smad4 0.0017 0.0035 0.0024
Schistosoma mansoni hypothetical protein 0.0066 0.0345 0.0688
Mycobacterium ulcerans peptide synthetase Nrp (peptide synthase) 0.0066 0.0345 0.0495
Plasmodium vivax hypothetical protein, conserved 0.0098 0.0542 0.5652
Onchocerca volvulus 0.0027 0.0098 0.0038
Leishmania major nuclear receptor binding factor-like protein 0.0041 0.0186 0.138
Echinococcus multilocularis guanine nucleotide binding protein G(s) subunit 0.0045 0.0214 0.0202
Schistosoma mansoni Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) 0.0045 0.0214 0.0427
Echinococcus granulosus microtubule associated protein 2 0.0683 0.4192 0.8364
Schistosoma mansoni ataxia telangiectasia mutated (atm) 0.0025 0.0086 0.0171
Mycobacterium tuberculosis Possible quinone oxidoreductase (NADPH:quinone oxidoreductase) (zeta-crystallin) 0.0041 0.0186 0.023
Trichomonas vaginalis rotamase, putative 0.0033 0.0138 0.1167
Echinococcus multilocularis cpg binding protein 0.006 0.0308 0.0297
Leishmania major ubiquitin hydrolase, putative,cysteine peptidase, Clan CA, family C19, putative 0.0074 0.0394 0.3216
Schistosoma mansoni [ACP] S-malonyltransferase 0.0041 0.019 0.0378
Loa Loa (eye worm) hypothetical protein 0.0041 0.019 0.0279
Mycobacterium tuberculosis Possible oxidoreductase FadB5 0.0041 0.0186 0.023
Mycobacterium leprae PHENOLPTHIOCEROL SYNTHESIS TYPE-I POLYKETIDE SYNTHASE PPSC 0.0697 0.4279 0.706
Toxoplasma gondii type I fatty acid synthase 0.0101 0.0559 0.1303
Onchocerca volvulus Cathepsin L homolog 0.0033 0.0139 0.0095
Plasmodium vivax vivapain-3 0.0017 0.0038 0.04
Echinococcus granulosus lamin 0.0027 0.0098 0.0172
Trypanosoma cruzi isocitrate dehydrogenase, putative 0.0032 0.0133 0.139
Echinococcus multilocularis phosphatidylinositol 3 and 4 kinase 0.0018 0.0044 0.0032
Brugia malayi ImpB/MucB/SamB family protein 0.0019 0.0052 0.0067
Mycobacterium leprae PROBABLE NADP-DEPENDENT ALCOHOL DEHYDROGENASE ADHC 0.0041 0.0186 0.026
Schistosoma mansoni gcn5proteinral control of amino-acid synthesis 5-like 2 gcnl2 0.0152 0.0879 0.1755
Toxoplasma gondii target of rapamycin (TOR), putative 0.0018 0.0044 0.0098
Trypanosoma brucei Trans-2-enoyl-ACP reductase 2, putative 0.0041 0.0186 0.192
Toxoplasma gondii isocitrate dehydrogenase 0.0032 0.0133 0.0307
Brugia malayi MH2 domain containing protein 0.0017 0.0035 0.0046
Mycobacterium tuberculosis Probable polyketide synthase Pks5 0.0636 0.3899 0.6418
Schistosoma mansoni SmCL2-like peptidase (C01 family) 0.0017 0.0038 0.0077
Mycobacterium tuberculosis Probable NADPH quinone oxidoreductase FadB4 (NADPH:quinone reductase) (zeta-crystallin) 0.0041 0.0186 0.023
Onchocerca volvulus 0.0041 0.0186 0.0159
Toxoplasma gondii histone lysine acetyltransferase GCN5-A 0.0045 0.021 0.0487
Echinococcus multilocularis 3 oxoacyl (acyl carrier protein) synthase 0.0165 0.0959 0.0948
Mycobacterium tuberculosis Polyketide synthetase MbtD (polyketide synthase) 0.0202 0.119 0.1903
Mycobacterium tuberculosis Probable thioesterase TesA 0.0547 0.3342 0.549
Schistosoma mansoni Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) 0.0045 0.0214 0.0427
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0033 0.0139 0.1181
Schistosoma mansoni SmCL2-like peptidase (C01 family) 0.0017 0.0038 0.0077
Mycobacterium ulcerans thioesterase TesA 0.0547 0.3342 0.549
Leishmania major zinc-binding dehydrogenase-like protein 0.0041 0.0186 0.138
Loa Loa (eye worm) hypothetical protein 0.0041 0.0186 0.0273
Loa Loa (eye worm) hypothetical protein 0.0022 0.007 0.0103
Trypanosoma cruzi nuclear receptor binding factor, putative 0.0041 0.0186 0.1935
Toxoplasma gondii isocitrate dehydrogenase 0.0032 0.0133 0.0307
Trypanosoma brucei beta-ketoacyl-ACP synthase 0.0165 0.0959 1
Echinococcus multilocularis smad 0.0017 0.0035 0.0024
Onchocerca volvulus Protein cycle homolog 0.0037 0.016 0.0124
Mycobacterium tuberculosis Probable membrane bound polyketide synthase Pks6 0.098 0.6049 1
Schistosoma mansoni rab geranylgeranyl transferase alpha subunit 0.0019 0.0052 0.0103
Trypanosoma cruzi ubiquitin carboxyl-terminal hydrolase, putative 0.0074 0.0394 0.4111
Giardia lamblia Ubiquitin carboxyl-terminal hydrolase 4 0.0074 0.0394 0.3127
Toxoplasma gondii quinone oxidoreductase, putative 0.0041 0.0186 0.0429
Trichomonas vaginalis Clan CA, family C19, ubiquitin hydrolase-like cysteine peptidase 0.0074 0.0394 0.3374
Trypanosoma cruzi oxidoreductase, putative 0.0041 0.0186 0.1935
Mycobacterium tuberculosis Probable peptide synthetase Nrp (peptide synthase) 0.0066 0.0345 0.0495
Onchocerca volvulus Cathepsin L homolog 0.0033 0.0139 0.0095
Mycobacterium leprae PROBABLE POLYKETIDE BETA-KETOACYL SYNTHASE PKS4 0.0101 0.0559 0.0881
Trypanosoma cruzi Phosphatidylinositol 3-kinase tor1 0.0018 0.0044 0.0454
Trypanosoma brucei acyl transferase-like protein 0.0041 0.019 0.1963
Wolbachia endosymbiont of Brugia malayi 3-oxoacyl-ACP synthase 0.0165 0.0959 1
Trypanosoma brucei DNA polymerase IV, putative 0.0019 0.0052 0.0521
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0033 0.0139 0.1181
Echinococcus multilocularis FKBP12 rapamycin complex associated protein 0.0018 0.0044 0.0032
Entamoeba histolytica hypothetical protein 0.0036 0.0153 0.3235
Trichomonas vaginalis alcohol dehydrogenase, putative 0.0041 0.0186 0.158
Brugia malayi Cathepsin L-like precursor 0.0033 0.0139 0.0181
Trypanosoma cruzi cysteine peptidase (N-terminal), putative 0.0017 0.0038 0.04
Onchocerca volvulus 0.0033 0.0139 0.0095
Mycobacterium leprae PHENOLPTHIOCEROL SYNTHESIS TYPE-I POLYKETIDE SYNTHASE PPSE 0.0434 0.2638 0.4334
Echinococcus multilocularis cathepsin L cysteine protease 0.0033 0.0139 0.0128
Mycobacterium tuberculosis Possible DNA-damage-inducible protein P DinP (DNA polymerase V) (pol IV 2) (DNA nucleotidyltransferase (DNA-directed)) 0.0019 0.0052 0.0007
Loa Loa (eye worm) hypothetical protein 0.0021 0.0064 0.0094
Echinococcus granulosus lamin dm0 0.0027 0.0098 0.0172
Leishmania major acyl carrier protein, putative 0.0066 0.0345 0.2782
Mycobacterium ulcerans Type I modular polyketide synthase 0.0656 0.4024 0.6627
Trypanosoma cruzi Phosphatidylinositol 3-kinase tor2 0.0018 0.0044 0.0454
Trichomonas vaginalis PIKK family atypical protein kinase 0.0018 0.0044 0.0359
Toxoplasma gondii histone lysine acetyltransferase GCN5-B 0.0045 0.021 0.0487
Plasmodium vivax vivapain-2 0.0033 0.0139 0.1452
Trichomonas vaginalis Clan CA, family C1, papain-like cysteine peptidase 0.0033 0.0139 0.1181
Trichomonas vaginalis conserved hypothetical protein 0.0013 0.0012 0.0088
Echinococcus multilocularis aryl hydrocarbon receptor 0.0052 0.0258 0.0246
Trypanosoma cruzi major cysteine proteinase, putative 0.01 0.0554 0.5778
Loa Loa (eye worm) hypothetical protein 0.0011 0.0002 0.0003
Echinococcus multilocularis NADH dehydrogenase 0.0066 0.0345 0.0333
Trypanosoma cruzi NADP-dependent alcohol hydrogenase, putative 0.0041 0.0186 0.1935
Trichomonas vaginalis PIKK family atypical protein kinase 0.0018 0.0044 0.0359
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0033 0.0139 0.1181
Trypanosoma cruzi acyl transferase-like protein 0.0041 0.019 0.1978
Trichomonas vaginalis PIKK family atypical protein kinase 0.0018 0.0044 0.0359
Loa Loa (eye worm) isocitrate dehydrogenase 0.0032 0.0133 0.0196
Echinococcus multilocularis Malonyl coenzyme A acyl carrier protein transacylase 0.0041 0.019 0.0178
Leishmania major cathepsin L-like protease 0.0033 0.0139 0.0972
Mycobacterium ulcerans 3-oxoacyl-(acyl carrier protein) synthase II 0.0165 0.0959 0.1518
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0127 0.0723 0.7541
Wolbachia endosymbiont of Brugia malayi ACP S-malonyltransferase 0.0041 0.019 0.1561
Echinococcus multilocularis Peptidase C19, ubiquitin carboxyl terminal hydrolase 2 0.0074 0.0394 0.0383
Loa Loa (eye worm) hypothetical protein 0.0041 0.0186 0.0273
Trichomonas vaginalis chromodomain-helicase-DNA-binding protein, putative 0.0013 0.0012 0.0088
Mycobacterium tuberculosis Probable alcohol dehydrogenase AdhA 0.0041 0.0186 0.023
Mycobacterium tuberculosis Conserved protein 0.0198 0.1164 0.1861
Entamoeba histolytica acetyltransferase, GNAT family 0.0041 0.0187 0.4175
Brugia malayi hypothetical protein 0.0037 0.016 0.0208
Loa Loa (eye worm) fatty acid synthase 0.0647 0.397 0.5832
Leishmania major cathepsin L-like protease 0.0127 0.0723 0.6117
Mycobacterium tuberculosis Phenolpthiocerol synthesis type-I polyketide synthase PpsA 0.0656 0.4024 0.6627
Echinococcus multilocularis gcn5proteinral control of amino acid synthesis 0.0152 0.0879 0.0869
Trichomonas vaginalis bromodomain-containing protein, putative 0.0045 0.021 0.1791
Brugia malayi Helix-loop-helix DNA-binding domain containing protein 0.0037 0.016 0.0208
Toxoplasma gondii Zn-containing alcohol dehydrogenase 0.0041 0.0186 0.0429
Mycobacterium tuberculosis Phenolpthiocerol synthesis type-I polyketide synthase PpsD 0.0656 0.4024 0.6627
Schistosoma mansoni mixed-lineage leukemia protein mll 0.0121 0.0688 0.1373
Plasmodium vivax vivapain-1 0.0017 0.0038 0.04
Trichomonas vaginalis ap endonuclease, putative 0.0019 0.0047 0.0392
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0127 0.0723 0.7541
Schistosoma mansoni zinc binding dehydrogenase 0.0041 0.0186 0.037
Plasmodium vivax acyl carrier protein, putative 0.0066 0.0345 0.3596
Mycobacterium tuberculosis Probable fatty-acid-CoA ligase FadD9 (fatty-acid-CoA synthetase) (fatty-acid-CoA synthase) 0.0066 0.0345 0.0495
Entamoeba histolytica acyl-CoA synthetase, putative 0.0066 0.0345 0.8612
Loa Loa (eye worm) MH2 domain-containing protein 0.0245 0.1457 0.2141
Mycobacterium tuberculosis Meromycolate extension acyl carrier protein AcpM 0.0066 0.0345 0.0495
Echinococcus granulosus mixed lineage leukemia protein mll 0.0014 0.002 0.0016
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0033 0.0139 0.1181
Trypanosoma cruzi cysteine peptidase, clan CA, family C1, cathepsin L-like, putative 0.0116 0.0655 0.6829
Echinococcus multilocularis NADP dependent isocitrate dehydrogenase 0.0032 0.0133 0.0122
Trypanosoma cruzi STE group serine/threonine-protein kinase, putative 0.0016 0.0029 0.0301
Leishmania major cathepsin L-like protease 0.0033 0.0139 0.0972
Leishmania major peptidyl-prolyl cis-trans isomerase/rotamase, putative,PPIase, putative 0.0032 0.0133 0.0914
Entamoeba histolytica acyl-CoA synthetase, putative 0.0066 0.0345 0.8612
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0022 0.007 0.059
Trypanosoma cruzi NADP-dependent alcohol hydrogenase, putative 0.0041 0.0186 0.1935
Trypanosoma cruzi peptidyl-prolyl cis-trans isomerase 0.0032 0.0133 0.1384
Mycobacterium ulcerans DNA polymerase IV 0.0019 0.0052 0.0007
Brugia malayi Phosphopantetheine attachment site family protein 0.0066 0.0345 0.0448
Brugia malayi oxidoreductase, zinc-binding dehydrogenase family protein 0.0041 0.0186 0.0241
Trichomonas vaginalis conserved hypothetical protein 0.0013 0.0012 0.0088
Onchocerca volvulus 0.0041 0.0186 0.0159
Leishmania major cathepsin L-like protease 0.0033 0.0139 0.0972
Mycobacterium leprae Probable alcohol dehydrogenase AdhA 0.0041 0.0186 0.026
Loa Loa (eye worm) acyl carrier protein 0.0302 0.1813 0.2664
Echinococcus granulosus cathepsin L cysteine protease 0.0017 0.0038 0.0053
Schistosoma mansoni cathepsin F (C01 family) 0.0022 0.007 0.0141
Trichomonas vaginalis adenylate and guanylate cyclases, putative 0.0016 0.0029 0.0232
Brugia malayi ImpB/MucB/SamB family protein 0.0019 0.0052 0.0067
Echinococcus multilocularis cysteine protease 0.0033 0.0139 0.0128
Brugia malayi isocitrate dehydrogenase 0.0032 0.0133 0.0173
Trypanosoma brucei isocitrate dehydrogenase [NADP], mitochondrial precursor, putative 0.0032 0.0133 0.1373
Leishmania major phosphatidylinositol kinase related protein, putative 0.0018 0.0044 0.0132
Brugia malayi Pin1-type peptidyl-prolyl cis-trans isomerase, BmPin1 0.0033 0.0138 0.0179
Trichomonas vaginalis PIKK family atypical protein kinase 0.0018 0.0044 0.0359
Loa Loa (eye worm) MH2 domain-containing protein 0.0017 0.0035 0.0052
Echinococcus multilocularis Acyl carrier protein, mitochondrial 0.0066 0.0345 0.0333
Mycobacterium ulcerans polyketide synthase 0.0697 0.4279 0.705
Trichomonas vaginalis conserved hypothetical protein 0.0013 0.0012 0.0088
Echinococcus granulosus dna polymerase eta 0.0019 0.0052 0.008
Brugia malayi Phosphatidylinositol 3- and 4-kinase family protein 0.0025 0.0086 0.0111
Trichomonas vaginalis guanylate cyclase, putative 0.0016 0.0029 0.0232
Brugia malayi exodeoxyribonuclease III family protein 0.0019 0.0047 0.0062
Toxoplasma gondii histone lysine methyltransferase SET1 0.0112 0.063 0.1469
Echinococcus granulosus Malonyl coenzyme A acyl carrier protein transacylase 0.0041 0.019 0.0356
Schistosoma mansoni cpg binding protein 0.006 0.0308 0.0615
Trichomonas vaginalis conserved hypothetical protein 0.0013 0.0012 0.0088
Loa Loa (eye worm) intermediate filament protein 0.0027 0.0098 0.0144
Echinococcus multilocularis NADP dependent isocitrate dehydrogenase 0.0032 0.0133 0.0122
Brugia malayi acetyltransferase, GNAT family protein 0.0152 0.0879 0.1144
Mycobacterium tuberculosis Probable polyketide beta-ketoacyl synthase Pks3 0.0101 0.0559 0.0853
Echinococcus multilocularis NADP dependent isocitrate dehydrogenase 0.0032 0.0133 0.0122
Mycobacterium tuberculosis Polyketide synthase Pks12 0.0697 0.4279 0.705
Echinococcus granulosus Smad4 0.0017 0.0035 0.0047
Trichomonas vaginalis PIKK family atypical protein kinase 0.0018 0.0044 0.0359
Onchocerca volvulus Putative alcohol dehydrogenase 0.0041 0.0186 0.0159
Mycobacterium ulcerans DNA polymerase IV 0.0019 0.0052 0.0007
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0033 0.0139 0.1181
Mycobacterium ulcerans phenolpthiocerol synthesis type-I polyketide synthase PpsC 0.0697 0.4279 0.705
Echinococcus multilocularis musashi 0.0027 0.0098 0.0086
Trichomonas vaginalis Clan CA, family C1, papain-like cysteine peptidase 0.0033 0.0139 0.1181
Loa Loa (eye worm) hypothetical protein 0.0019 0.0052 0.0076
Echinococcus granulosus terminal deoxycytidyl transferase rev1 0.0019 0.0052 0.008
Echinococcus multilocularis lamin dm0 0.0027 0.0098 0.0086
Mycobacterium tuberculosis Probable polyketide synthase Pks1 0.0471 0.2872 0.4706
Brugia malayi cathepsin L-like precursor 0.0022 0.007 0.0092
Trichomonas vaginalis rotamase, putative 0.0032 0.0133 0.1125
Mycobacterium tuberculosis Probable NADP-dependent alcohol dehydrogenase AdhC 0.0041 0.0186 0.023
Mycobacterium tuberculosis Peptide synthetase MbtF (peptide synthase) 0.0066 0.0345 0.0495
Leishmania major phosphatidylinositol 3-kinase, putative 0.0018 0.0044 0.013
Brugia malayi MH1 domain containing protein 0.0017 0.0035 0.0046
Brugia malayi MH2 domain containing protein 0.0017 0.0035 0.0046
Trypanosoma cruzi phosphatidylinositol kinase related protein, putative 0.0018 0.0044 0.0457
Echinococcus multilocularis ubiquitin carboxyl terminal hydrolase 8 0.0074 0.0394 0.0383
Brugia malayi Cathepsin L-like precursor 0.0033 0.0139 0.0181
Trichomonas vaginalis cat eye syndrome critical region protein 2, cscr2, putative 0.0045 0.021 0.1791
Trypanosoma cruzi DNA polymerase kappa, putative 0.0019 0.0052 0.054
Trypanosoma cruzi phosphatidylinositol kinase related protein, putative 0.0021 0.0064 0.0667
Trichomonas vaginalis ap endonuclease, putative 0.0019 0.0047 0.0392
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0033 0.0139 0.1181
Treponema pallidum acyl carrier protein 0.0066 0.0345 1
Mycobacterium ulcerans zinc-containing alcohol dehydrogenase NAD-dependent AdhB 0.0041 0.0186 0.023
Loa Loa (eye worm) hypothetical protein 0.0036 0.0159 0.0233
Echinococcus granulosus cathepsin L 0.0017 0.0038 0.0053
Trypanosoma cruzi DNA polymerase kappa, putative 0.0019 0.0052 0.054
Trypanosoma cruzi apurinic/apyrimidinic endonuclease, putative 0.0019 0.0047 0.0494
Schistosoma mansoni acyl carrier protein 0.0066 0.0345 0.0688
Trichomonas vaginalis PIKK family atypical protein kinase 0.0018 0.0044 0.0359
Schistosoma mansoni aryl hydrocarbon receptor nuclear translocator homolog (darnt) 0.0037 0.016 0.032
Trichomonas vaginalis adenylate and guanylate cyclases, putative 0.0016 0.0029 0.0232
Echinococcus multilocularis geminin 0.0521 0.3182 0.3174
Trypanosoma brucei unspecified product 0.0013 0.0014 0.0131
Trichomonas vaginalis PIKK family atypical protein kinase 0.0018 0.0044 0.0359
Loa Loa (eye worm) hypothetical protein 0.0036 0.0159 0.0233
Trypanosoma cruzi cysteine peptidase, putative 0.0033 0.0139 0.1452
Echinococcus multilocularis serine protein kinase ATM 0.0025 0.0086 0.0074
Brugia malayi PAS domain containing protein 0.0016 0.0029 0.0038
Trichomonas vaginalis chromodomain helicase DNA binding protein, putative 0.0013 0.0012 0.0088
Trichomonas vaginalis alcohol dehydrogenase, putative 0.0041 0.0186 0.158
Trypanosoma cruzi PAS-domain containing phosphoglycerate kinase, putative 0.0016 0.0029 0.0301
Schistosoma mansoni hypothetical protein 0.0814 0.501 1
Toxoplasma gondii beta-ketoacyl synthase, N-terminal domain-containing protein 0.0425 0.2587 0.6044
Onchocerca volvulus 0.0033 0.0139 0.0095
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0022 0.007 0.059
Leishmania major target of rapamycin (TOR) kinase 1, putative 0.0018 0.0044 0.013
Loa Loa (eye worm) hypothetical protein 0.1102 0.6807 1
Schistosoma mansoni DNA polymerase eta 0.0019 0.0052 0.0103
Trichomonas vaginalis conserved hypothetical protein 0.0033 0.0138 0.1167
Trypanosoma brucei target of rapamycin kinase 3, putative 0.0018 0.0044 0.0436
Echinococcus granulosus Aryl hydrocarbon receptor nuclear 0.0016 0.003 0.0038
Mycobacterium ulcerans oxidoreductase FadB5 0.0041 0.0186 0.023
Trichomonas vaginalis soluble guanylate cyclase gcy, putative 0.0016 0.0029 0.0232
Mycobacterium tuberculosis Probable isocitrate dehydrogenase [NADP] Icd1 (oxalosuccinate decarboxylase) (IDH) (NADP+-specific ICDH) (IDP) 0.0032 0.0133 0.0143
Trichomonas vaginalis guanylate cyclase, putative 0.0016 0.0029 0.0232
Mycobacterium ulcerans phenolpthiocerol synthesis type-I polyketide synthase PpsB 0.0528 0.3225 0.5294
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0033 0.0139 0.1181
Trichomonas vaginalis helicase, putative 0.0013 0.0012 0.0088
Mycobacterium ulcerans polyketide synthase 0.0656 0.4024 0.6627
Entamoeba histolytica exodeoxyribonuclease III, putative 0.0019 0.0047 0.0254
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0017 0.0038 0.0382
Trichomonas vaginalis PIKK family atypical protein kinase 0.0018 0.0044 0.0359
Echinococcus multilocularis ubiquitin specific protease 41 0.0074 0.0394 0.0383
Trichomonas vaginalis PIKK family atypical protein kinase 0.0025 0.0086 0.072
Schistosoma mansoni smad1 5 8 and 0.0017 0.0035 0.007
Trichomonas vaginalis conserved hypothetical protein 0.0013 0.0012 0.0088
Mycobacterium tuberculosis Peptide synthetase MbtE (peptide synthase) 0.0066 0.0345 0.0495
Trypanosoma brucei isocitrate dehydrogenase, putative 0.0032 0.0133 0.1373
Loa Loa (eye worm) cytoplasmic intermediate filament protein 0.0014 0.002 0.003
Echinococcus granulosus NADP dependent isocitrate dehydrogenase 0.0032 0.0133 0.0243
Mycobacterium tuberculosis Probable acyl carrier protein AcpA (ACP) 0.0066 0.0345 0.0495
Trypanosoma cruzi cysteine proteinase, putative 0.0017 0.0038 0.04
Echinococcus granulosus smad 0.0017 0.0035 0.0047
Onchocerca volvulus 0.0027 0.0098 0.0038
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0033 0.0139 0.1181
Echinococcus granulosus AMP dependent ligase 0.0066 0.0345 0.0666
Mycobacterium ulcerans zinc-dependent alcohol dehydrogenase AdhE2 0.0041 0.0186 0.023
Mycobacterium leprae PHENOLPTHIOCEROL SYNTHESIS TYPE-I POLYKETIDE SYNTHASE PPSA 0.0656 0.4024 0.6637
Mycobacterium ulcerans NADP-dependent alcohol dehydrogenase Adh 0.0041 0.0186 0.023
Mycobacterium tuberculosis Phenyloxazoline synthase MbtB (phenyloxazoline synthetase) 0.0613 0.3755 0.6179
Plasmodium falciparum conserved Plasmodium protein, unknown function 0.0098 0.0542 0.547
Loa Loa (eye worm) hypothetical protein 0.0033 0.0139 0.0204
Plasmodium falciparum cysteine proteinase falcipain 2b 0.0033 0.0139 0.1095
Loa Loa (eye worm) hypothetical protein 0.0041 0.0186 0.0273
Schistosoma mansoni lamin 0.0027 0.0098 0.0195
Onchocerca volvulus Cathepsin F homolog 0.0033 0.0139 0.0095
Trypanosoma brucei oxidoreductase, putative 0.0041 0.0186 0.192
Brugia malayi F/Y-rich N-terminus family protein 0.0017 0.004 0.0052
Loa Loa (eye worm) hypothetical protein 0.0022 0.007 0.0103
Mycobacterium ulcerans 3-oxoacyl-(acyl carrier protein) synthase II 0.0165 0.0959 0.1518

Activities

Activity type Activity value Assay description Source Reference
Potency (functional) 125.8925 uM PubChem BioAssay. qHTS of PTHR Inhibitors: Primary Screen. (Class of assay: confirmatory) ChEMBL. No reference

Phenotypes

Whole-cell/tissue/organism interactions

We have no records of whole-cell/tissue assays done with this compound What does this mean?

Many chemical entities in TDR Targets come from high-throughput screenings with whole cells or tissue samples, and not all assayed compounds have been tested against a single a single target protein, probably because they get ruled out during screening process. Even if these compounds may have not been of interest in the original screening, they may come as interesting leads for other screening assays. Furthermore, we may be able to propose drug-target associations using chemical similarities and network patterns.

Annotated phenotypes:

We have no manually annotated phenotypes for this drug. What does this mean? / Care to help?
In TDR Targets, information about phenotypes that are caused by drugs, or by genetic manipulation of cells (e.g. gene knockouts or knockdowns) is manually curated from the literature. These descriptions help to describe the potential of the target for drug development. If no information is available for this gene or if the information is incomplete, this may mean that i) the papers containing this information either appeared after the curation effort for this organism was carried out or they were inadvertently missed by curators; or that ii) the curation effort for this organism has not yet started.
 
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External resources for this compound

Bibliographic References

No literature references available for this target.

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