Detailed information for compound 163586

Basic information

Technical information
  • Name: Unnamed compound
  • MW: 464.565 | Formula: C27H28N8
  • H donors: 1 H acceptors: 6 LogP: 4.54 Rotable bonds: 8
    Rule of 5 violations (Lipinski): 1
  • SMILES: CCCCc1nc(cn1Cc1ccc(cc1)c1ccccc1c1n[nH]nn1)c1nc(C)cnc1C
  • InChi: 1S/C27H28N8/c1-4-5-10-25-30-24(26-19(3)28-15-18(2)29-26)17-35(25)16-20-11-13-21(14-12-20)22-8-6-7-9-23(22)27-31-33-34-32-27/h6-9,11-15,17H,4-5,10,16H2,1-3H3,(H,31,32,33,34)
  • InChiKey: NVUIBGHVPKYGQZ-UHFFFAOYSA-N  


Substructure search Similarity search

Network

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Synonyms

No synonyms found for this compound

Targets

Known targets for this compound

Species Target name Source Bibliographic reference
Rattus norvegicus Angiotensin II receptor (AT-1) type-1 Starlite/ChEMBL References

Predicted pathogen targets for this compound

By orthology
No druggable targets predicted by orthology data
By sequence similarity to non orthologous known druggable targets
Species Potential target Known druggable target Length Alignment span Identity
Echinococcus multilocularis tm gpcr rhodopsin gpcr rhodopsin superfamily Angiotensin II receptor (AT-1) type-1   359 aa 300 aa 21.0 %
Schistosoma mansoni opsin-like receptor Angiotensin II receptor (AT-1) type-1   359 aa 299 aa 25.8 %
Onchocerca volvulus Angiotensin II receptor (AT-1) type-1   359 aa 305 aa 24.9 %
Loa Loa (eye worm) hypothetical protein Angiotensin II receptor (AT-1) type-1   359 aa 329 aa 24.0 %
Echinococcus multilocularis thyrotropin releasing hormone receptor Angiotensin II receptor (AT-1) type-1   359 aa 363 aa 23.4 %
Onchocerca volvulus Angiotensin II receptor (AT-1) type-1   359 aa 386 aa 24.4 %
Schistosoma mansoni peptide (FMRFamide/somatostatin)-like receptor Angiotensin II receptor (AT-1) type-1   359 aa 346 aa 18.2 %
Schistosoma japonicum ko:K04134 cholinergic receptor, invertebrate, putative Angiotensin II receptor (AT-1) type-1   359 aa 325 aa 20.9 %
Onchocerca volvulus Angiotensin II receptor (AT-1) type-1   359 aa 355 aa 23.9 %
Echinococcus granulosus pyroglutamylated rfamide peptide receptor Angiotensin II receptor (AT-1) type-1   359 aa 366 aa 19.7 %
Loa Loa (eye worm) hypothetical protein Angiotensin II receptor (AT-1) type-1   359 aa 308 aa 27.6 %
Echinococcus granulosus growth hormone secretagogue receptor type 1 Angiotensin II receptor (AT-1) type-1   359 aa 343 aa 23.0 %
Schistosoma mansoni biogenic amine (octopamine/dopamine) receptor Angiotensin II receptor (AT-1) type-1   359 aa 350 aa 23.1 %
Onchocerca volvulus Angiotensin II receptor (AT-1) type-1   359 aa 309 aa 18.8 %
Echinococcus granulosus allatostatin A receptor Angiotensin II receptor (AT-1) type-1   359 aa 342 aa 27.2 %
Echinococcus granulosus tm gpcr rhodopsin Angiotensin II receptor (AT-1) type-1   359 aa 300 aa 21.0 %
Brugia malayi putative neuropeptide receptor NPR1 Angiotensin II receptor (AT-1) type-1   359 aa 295 aa 27.1 %
Loa Loa (eye worm) neuropeptide F receptor Angiotensin II receptor (AT-1) type-1   359 aa 344 aa 23.5 %
Echinococcus multilocularis G-protein coupled receptor, putative Angiotensin II receptor (AT-1) type-1   359 aa 307 aa 22.1 %
Echinococcus granulosus neuropeptide receptor Angiotensin II receptor (AT-1) type-1   359 aa 317 aa 24.6 %
Echinococcus multilocularis allatostatin A receptor Angiotensin II receptor (AT-1) type-1   359 aa 342 aa 26.6 %
Schistosoma japonicum ko:K04209 neuropeptide Y receptor, invertebrate, putative Angiotensin II receptor (AT-1) type-1   359 aa 307 aa 24.1 %
Onchocerca volvulus Angiotensin II receptor (AT-1) type-1   359 aa 350 aa 24.0 %
Echinococcus multilocularis neuropeptide receptor Angiotensin II receptor (AT-1) type-1   359 aa 317 aa 24.9 %
Onchocerca volvulus E3 ubiquitin-protein ligase rpm-1 homolog Angiotensin II receptor (AT-1) type-1   359 aa 354 aa 20.6 %
Brugia malayi GnHR receptor homolog Angiotensin II receptor (AT-1) type-1   359 aa 357 aa 20.4 %
Onchocerca volvulus Angiotensin II receptor (AT-1) type-1   359 aa 314 aa 25.2 %
Echinococcus multilocularis pyroglutamylated rfamide peptide receptor Angiotensin II receptor (AT-1) type-1   359 aa 365 aa 20.0 %
Onchocerca volvulus Angiotensin II receptor (AT-1) type-1   359 aa 292 aa 24.7 %
Echinococcus granulosus thyrotropin releasing hormone receptor Angiotensin II receptor (AT-1) type-1   359 aa 363 aa 23.7 %
Brugia malayi ORL1-like opioid receptor Angiotensin II receptor (AT-1) type-1   359 aa 314 aa 20.4 %
Schistosoma mansoni peptide (allatostatin)-like receptor Angiotensin II receptor (AT-1) type-1   359 aa 323 aa 25.7 %
Obtained from network model

Ranking Plot

Putative Targets List

Species Potential target Raw Global Species
Loa Loa (eye worm) plexin A 0.107 0.2064 0.2064
Loa Loa (eye worm) hypothetical protein 0.0056 0.006 0.006
Schistosoma mansoni serine/threonine protein kinase 0.0056 0.006 0.006
Trichomonas vaginalis conserved hypothetical protein 0.0056 0.006 0.0327
Trypanosoma cruzi NEK family Serine/threonine-protein kinase, putative 0.0096 0.0139 1
Echinococcus multilocularis regulator of G protein signaling 7 0.0824 0.1579 0.1886
Loa Loa (eye worm) GTP-ase activating protein for Arf containing protein 0.0076 0.0098 0.0098
Schistosoma mansoni defective proboscis extension response (dpr)-related 0.0096 0.0139 0.0139
Schistosoma mansoni z-protein (S1r protein) 0.0824 0.1579 0.1579
Trichomonas vaginalis AGC family protein kinase 0.0096 0.0139 0.0827
Echinococcus multilocularis proto oncogene tyrosine protein kinase LCK 0.0056 0.006 0.0072
Brugia malayi GTPase-activator protein for Ras-like GTPase containing protein 0.0076 0.0098 0.0098
Echinococcus multilocularis receptor type guanylyl cyclase 0.0056 0.006 0.0072
Loa Loa (eye worm) hypothetical protein 0.0168 0.028 0.028
Trichomonas vaginalis TKL family protein kinase 0.0056 0.006 0.0327
Schistosoma mansoni myotubularin-related protein 0.0076 0.0098 0.0098
Trichomonas vaginalis TKL family protein kinase 0.0056 0.006 0.0327
Loa Loa (eye worm) hypothetical protein 0.0096 0.0139 0.0139
Loa Loa (eye worm) RGC/RGC protein kinase 0.0056 0.006 0.006
Schistosoma mansoni hypothetical protein 0.0168 0.028 0.028
Trichomonas vaginalis tubulin beta chain, putative 0.0038 0.0024 0.0095
Echinococcus multilocularis axis inhibition protein axin 0.0824 0.1579 0.1886
Schistosoma mansoni regulator of G protein signaling 0.0824 0.1579 0.1579
Echinococcus multilocularis Immunoglobulin 0.0096 0.0139 0.0166
Entamoeba histolytica protein kinase domain containing protein 0.0056 0.006 0.0327
Trichomonas vaginalis AGC family protein kinase 0.0096 0.0139 0.0827
Loa Loa (eye worm) hypothetical protein 0.0824 0.1579 0.1579
Entamoeba histolytica protein kinase domain containing protein 0.0056 0.006 0.0327
Trichomonas vaginalis tubulin, putative 0.0038 0.0024 0.0095
Brugia malayi Protein kinase domain containing protein 0.0056 0.006 0.006
Echinococcus granulosus tyrosine kinase|tyrosine protein kinase Fyn 0.0056 0.006 0.0072
Trichomonas vaginalis conserved hypothetical protein 0.0168 0.028 0.173
Trichomonas vaginalis conserved hypothetical protein 0.0076 0.0098 0.0571
Echinococcus multilocularis tyrosine kinase 0.0056 0.006 0.0072
Entamoeba histolytica protein kinase, putative 0.0096 0.0139 0.0827
Loa Loa (eye worm) tubulin beta-2A chain 0.0038 0.0024 0.0024
Loa Loa (eye worm) GTP-ase activating protein for Arf containing protein 0.0076 0.0098 0.0098
Loa Loa (eye worm) hypothetical protein 0.0036 0.002 0.002
Loa Loa (eye worm) hypothetical protein 0.0096 0.0139 0.0139
Trichomonas vaginalis AGC family protein kinase 0.0081 0.0109 0.0639
Plasmodium falciparum tyrosine kinase-like protein 0.0056 0.006 0.4338
Entamoeba histolytica protein kinase domain containing protein 0.0081 0.0109 0.0639
Echinococcus multilocularis tyrosine protein kinase csk 0.0056 0.006 0.0072
Entamoeba histolytica protein kinase, putative 0.0056 0.006 0.0327
Loa Loa (eye worm) tubulin alpha-2 chain 0.003 0.0009 0.0009
Echinococcus multilocularis collagen type iv alpha 3 binding protein 0.0076 0.0098 0.0118
Trichomonas vaginalis voltage and ligand gated potassium channel, putative 0.0039 0.0026 0.0108
Echinococcus multilocularis Tubulin beta 2C chain 0.0038 0.0024 0.0028
Echinococcus multilocularis Tubulin alpha 1 chain 0.003 0.0009 0.0011
Entamoeba histolytica protein kinase, putative 0.0056 0.006 0.0327
Brugia malayi PXA domain containing protein 0.0824 0.1579 0.1579
Schistosoma mansoni tyrosine protein kinase fes (fps) (ptk group IV) 0.0056 0.006 0.006
Entamoeba histolytica Rho guanine nucleotide exchange factor, putative 0.0076 0.0098 0.0571
Schistosoma mansoni tyrosine kinase 0.0056 0.006 0.006
Entamoeba histolytica protein kinase domain containing protein 0.0056 0.006 0.0327
Onchocerca volvulus 0.0037 0.0021 0.0059
Loa Loa (eye worm) hypothetical protein 0.0076 0.0098 0.0098
Echinococcus multilocularis tyrosine protein kinase lyn lyn a protein tyrosine kinase lymphocyte specific protein tyrosine kinase 0.0056 0.006 0.0072
Schistosoma mansoni serine/threonine protein kinase 0.5083 1 1
Entamoeba histolytica tyrosine kinase, putative 0.0056 0.006 0.0327
Echinococcus granulosus beta 1 syntrophin 0.0076 0.0098 0.0118
Schistosoma mansoni tyrosine kinase 0.0056 0.006 0.006
Schistosoma mansoni rhogef and pleckstrin domain protein 0.0076 0.0098 0.0098
Loa Loa (eye worm) hypothetical protein 0.0076 0.0098 0.0098
Echinococcus multilocularis tyrosine protein kinase HCK 0.0056 0.006 0.0072
Brugia malayi Protein kinase domain containing protein 0.0056 0.006 0.006
Schistosoma mansoni fibrocystin l 0.0168 0.028 0.028
Trypanosoma cruzi hypothetical protein 0.0076 0.0098 0.6904
Loa Loa (eye worm) hypothetical protein 0.0056 0.006 0.006
Echinococcus multilocularis tyrosine protein kinase Fgr 0.0056 0.006 0.0072
Leishmania major alpha tubulin 0.003 0.0009 0.0639
Onchocerca volvulus Atrial natriuretic peptide receptor 3 homolog 0.0056 0.006 0.0284
Trichomonas vaginalis AGC family protein kinase 0.0096 0.0139 0.0827
Echinococcus granulosus semaphorin 1A 0.0383 0.0706 0.0843
Schistosoma mansoni hypothetical protein 0.0383 0.0706 0.0706
Trichomonas vaginalis STE family protein kinase 0.0056 0.006 0.0327
Echinococcus multilocularis MAM 0.0032 0.0011 0.0013
Schistosoma mansoni protein kinase 0.0056 0.006 0.006
Brugia malayi Protein kinase domain containing protein 0.0056 0.006 0.006
Trichomonas vaginalis TKL family protein kinase 0.0056 0.006 0.0327
Entamoeba histolytica hypothetical protein 0.0076 0.0098 0.0571
Trichomonas vaginalis TKL family protein kinase 0.0056 0.006 0.0327
Schistosoma mansoni tubulin subunit alpha 0.003 0.0009 0.0009
Schistosoma mansoni tyrosine kinase 0.0056 0.006 0.006
Schistosoma mansoni tubulin subunit beta 0.0038 0.0024 0.0024
Brugia malayi Protein kinase domain containing protein 0.0056 0.006 0.006
Loa Loa (eye worm) hypothetical protein 0.0056 0.006 0.006
Brugia malayi Protein kinase domain containing protein 0.0056 0.006 0.006
Echinococcus granulosus Oxysterol binding protein 11 0.0076 0.0098 0.0118
Echinococcus multilocularis beta tubulin 0.0038 0.0024 0.0028
Loa Loa (eye worm) hypothetical protein 0.0824 0.1579 0.1579
Brugia malayi Protein kinase domain containing protein 0.0056 0.006 0.006
Echinococcus multilocularis tyrosine protein kinase Fyn 0.0056 0.006 0.0072
Entamoeba histolytica protein kinase domain containing protein 0.0056 0.006 0.0327
Entamoeba histolytica protein kinase domain containing protein 0.0056 0.006 0.0327
Trypanosoma brucei AGC/RSK family serine/threonine kinase, putative 0.0056 0.006 0.3952
Onchocerca volvulus 0.0076 0.0098 0.0506
Loa Loa (eye worm) TK/FER protein kinase 0.0056 0.006 0.006
Trichomonas vaginalis TKL family protein kinase 0.0056 0.006 0.0327
Echinococcus granulosus tubulin alpha 1C chain 0.003 0.0009 0.0011
Echinococcus multilocularis natriuretic peptide receptor 1 0.0056 0.006 0.0072
Trypanosoma cruzi STE/STE11 serine/threonine-protein kinase, putative 0.0077 0.01 0.7047
Trichomonas vaginalis TKL family protein kinase 0.0056 0.006 0.0327
Onchocerca volvulus 0.0076 0.0098 0.0506
Echinococcus multilocularis Pleckstrin y 0.0076 0.0098 0.0118
Echinococcus granulosus Pleckstrin y 0.0076 0.0098 0.0118
Entamoeba histolytica protein kinase domain containing protein 0.0056 0.006 0.0327
Schistosoma mansoni tyrosine protein kinase 0.0056 0.006 0.006
Echinococcus granulosus cytohesin 1 0.0076 0.0098 0.0118
Trichomonas vaginalis AGC family protein kinase 0.0081 0.0109 0.0639
Leishmania major beta tubulin 0.0038 0.0024 0.1716
Loa Loa (eye worm) TK/FER protein kinase 0.0056 0.006 0.006
Entamoeba histolytica protein kinase domain containing protein 0.0056 0.006 0.0327
Loa Loa (eye worm) hypothetical protein 0.0076 0.0098 0.0098
Trichomonas vaginalis kinesin light chain, putative 0.0076 0.0098 0.0571
Echinococcus multilocularis Pleckstrin y 0.0076 0.0098 0.0118
Entamoeba histolytica ankyrin repeat protein 0.0056 0.006 0.0327
Brugia malayi serine/threonine kinase 12 0.0081 0.0109 0.0109
Loa Loa (eye worm) TK protein kinase 0.0056 0.006 0.006
Entamoeba histolytica cell surface protease gp63, putative 0.0168 0.028 0.173
Trichomonas vaginalis TKL family protein kinase 0.0056 0.006 0.0327
Loa Loa (eye worm) TK protein kinase 0.0056 0.006 0.006
Echinococcus multilocularis Tubulin beta 2C chain 0.0038 0.0024 0.0028
Trichomonas vaginalis TKL family protein kinase 0.0056 0.006 0.0327
Loa Loa (eye worm) TK/FER protein kinase 0.0056 0.006 0.006
Leishmania major beta tubulin 0.0038 0.0024 0.1716
Echinococcus granulosus mitogen-activated protein kinase kinase kinase 9 0.0056 0.006 0.0072
Brugia malayi Cadps2 protein 0.0076 0.0098 0.0098
Toxoplasma gondii Tyrosine kinase-like (TKL) protein 0.0056 0.006 0.4338
Brugia malayi serine/threonine protein kinase 6 0.0081 0.0109 0.0109
Trichomonas vaginalis conserved hypothetical protein 0.0056 0.006 0.0327
Echinococcus granulosus Tubulin beta 2C chain 0.0038 0.0024 0.0028
Loa Loa (eye worm) hypothetical protein 0.0076 0.0098 0.0098
Schistosoma mansoni tyrosine kinase 0.0056 0.006 0.006
Loa Loa (eye worm) AGC/GRK/GRK protein kinase 0.5083 1 1
Schistosoma mansoni tyrosine kinase 0.0056 0.006 0.006
Echinococcus multilocularis tyrosine protein kinase pr2 0.0056 0.006 0.0072
Entamoeba histolytica hypothetical protein 0.0056 0.006 0.0327
Onchocerca volvulus 0.0056 0.006 0.0284
Loa Loa (eye worm) hypothetical protein 0.0056 0.006 0.006
Entamoeba histolytica hypothetical protein, conserved domain containing 0.0076 0.0098 0.0571
Loa Loa (eye worm) hypothetical protein 0.0056 0.006 0.006
Onchocerca volvulus 0.0076 0.0098 0.0506
Echinococcus multilocularis G protein coupled receptor kinase 1 0.3072 0.6024 0.7196
Trichomonas vaginalis AGC family protein kinase 0.0096 0.0139 0.0827
Entamoeba histolytica protein tyrosine kinase domain-containing protein 0.0056 0.006 0.0327
Echinococcus granulosus axis inhibition protein axin 0.0824 0.1579 0.1886
Loa Loa (eye worm) hypothetical protein 0.0056 0.006 0.006
Brugia malayi Probable tyrosine-protein kinase kin-31 0.0056 0.006 0.006
Brugia malayi Raf kinase 0.0056 0.006 0.006
Leishmania major alpha tubulin 0.003 0.0009 0.0639
Loa Loa (eye worm) hypothetical protein 0.0076 0.0098 0.0098
Schistosoma mansoni tyrosine kinase 0.0056 0.006 0.006
Echinococcus granulosus activated cdc42 kinase 1 0.0056 0.006 0.0072
Brugia malayi Fibronectin type III domain containing protein 0.0101 0.0149 0.0149
Echinococcus multilocularis peroxisome assembly protein 26 0.003 0.0009 0.0011
Loa Loa (eye worm) tubulin beta-1 chain 0.0038 0.0024 0.0024
Entamoeba histolytica PH domain containing protein kinase, putative 0.0096 0.0139 0.0827
Loa Loa (eye worm) TK/ROR protein kinase 0.0056 0.006 0.006
Echinococcus multilocularis tyrosine protein kinase Fyn 0.0056 0.006 0.0072
Schistosoma mansoni tubulin subunit beta 0.0038 0.0024 0.0024
Schistosoma mansoni semaphorin 5-related 0.0383 0.0706 0.0706
Entamoeba histolytica hypothetical protein 0.0076 0.0098 0.0571
Schistosoma mansoni proto-oncogene tyrosine-protein kinase src 0.0056 0.006 0.006
Echinococcus granulosus plexin a4 0.107 0.2064 0.2466
Trichomonas vaginalis TKL family protein kinase 0.0056 0.006 0.0327
Entamoeba histolytica hypothetical protein 0.0056 0.006 0.0327
Trichomonas vaginalis AGC family protein kinase 0.0096 0.0139 0.0827
Entamoeba histolytica tubulin family protein 0.0038 0.0024 0.0095
Brugia malayi Regulator of G protein signaling domain containing protein 0.0824 0.1579 0.1579
Trichomonas vaginalis TKL family protein kinase 0.0056 0.006 0.0327
Echinococcus multilocularis regulator of G protein signaling 3 0.0824 0.1579 0.1886
Echinococcus granulosus activated cdc42 kinase 1 0.0056 0.006 0.0072
Entamoeba histolytica tubulin family protein 0.0038 0.0024 0.0095
Trichomonas vaginalis conserved hypothetical protein 0.0056 0.006 0.0327
Echinococcus granulosus ras specific guanine nucleotide releasing factor 0.0076 0.0098 0.0118
Trichomonas vaginalis TKL family protein kinase 0.0056 0.006 0.0327
Loa Loa (eye worm) hypothetical protein 0.0383 0.0706 0.0706
Trichomonas vaginalis conserved hypothetical protein 0.0824 0.1579 1
Echinococcus granulosus tyrosine protein kinase Srms 0.0056 0.006 0.0072
Brugia malayi Protein kinase domain containing protein 0.0056 0.006 0.006
Onchocerca volvulus 0.0902 0.1733 1
Loa Loa (eye worm) hypothetical protein 0.0056 0.006 0.006
Trypanosoma brucei STE/STE11 serine/threonine-protein kinase, putative 0.0077 0.01 0.7047
Loa Loa (eye worm) hypothetical protein 0.0824 0.1579 0.1579
Brugia malayi Variant SH3 domain containing protein 0.0076 0.0098 0.0098
Plasmodium vivax PH domain containing protein 0.0076 0.0098 0.6904
Loa Loa (eye worm) TK/CSK protein kinase 0.0056 0.006 0.006
Echinococcus multilocularis oxysterol binding protein 1 0.0076 0.0098 0.0118
Trichomonas vaginalis protein transport protein sec7, putative 0.0076 0.0098 0.0571
Echinococcus granulosus basic fibroblast growth factor receptor 1 A 0.0056 0.006 0.0072
Echinococcus granulosus [G-protein-coupledreceptor] kinase 0.4259 0.837 1
Trichomonas vaginalis ankyrin repeat-containing protein, putative 0.0076 0.0098 0.0571
Brugia malayi hypothetical protein 0.0056 0.006 0.006
Loa Loa (eye worm) AGC/GRK/GRK protein kinase 0.4259 0.837 0.837
Loa Loa (eye worm) tubulin beta-4 chain 0.0038 0.0024 0.0024
Entamoeba histolytica protein kinase domain containing protein 0.0056 0.006 0.0327
Onchocerca volvulus 0.0056 0.006 0.0284
Schistosoma mansoni hypothetical protein 0.0056 0.006 0.006
Entamoeba histolytica hypothetical protein 0.0076 0.0098 0.0571
Trichomonas vaginalis TKL family protein kinase 0.0056 0.006 0.0327
Echinococcus granulosus tyrosine protein kinase Fyn 0.0056 0.006 0.0072
Loa Loa (eye worm) hypothetical protein 0.0076 0.0098 0.0098
Schistosoma mansoni regulator of G protein signaling 0.0824 0.1579 0.1579
Schistosoma mansoni serine/threonine protein kinase 0.0056 0.006 0.006
Schistosoma mansoni hypothetical protein 0.0032 0.0011 0.0011
Echinococcus granulosus transcription factor collier 0.0168 0.028 0.0335
Schistosoma mansoni rho gtpase activating protein 0.0076 0.0098 0.0098
Trichomonas vaginalis conserved hypothetical protein 0.0824 0.1579 1
Trichomonas vaginalis serine-threonine protein kinase, putative 0.0056 0.006 0.0327
Onchocerca volvulus 0.0056 0.006 0.0284
Trypanosoma cruzi Serine/threonine-protein kinase NEK21, putative 0.0096 0.0139 1
Onchocerca volvulus outspread protein homolog 0.0076 0.0098 0.0506
Loa Loa (eye worm) hypothetical protein 0.0824 0.1579 0.1579
Brugia malayi hypothetical protein 0.0101 0.0149 0.0149
Trichomonas vaginalis conserved hypothetical protein 0.0824 0.1579 1
Leishmania major beta tubulin 0.0038 0.0024 0.1716
Trichomonas vaginalis TKL family protein kinase 0.0056 0.006 0.0327
Trichomonas vaginalis TKL family protein kinase 0.0056 0.006 0.0327
Trypanosoma cruzi hypothetical protein 0.0076 0.0098 0.6904
Entamoeba histolytica Rho guanine nucleotide exchange factor, putative 0.0076 0.0098 0.0571
Entamoeba histolytica hypothetical protein 0.0056 0.006 0.0327
Echinococcus granulosus arf GAP with SH3 domain ANK repeat and PH 0.0076 0.0098 0.0118
Loa Loa (eye worm) TK/DDR protein kinase 0.0056 0.006 0.006
Trichomonas vaginalis TKL family protein kinase 0.0056 0.006 0.0327
Trichomonas vaginalis AGC family protein kinase 0.0096 0.0139 0.0827
Entamoeba histolytica protein kinase, putative 0.0056 0.006 0.0327
Echinococcus granulosus pdz domain containing protein 0.0076 0.0098 0.0118
Schistosoma mansoni tyrosine kinase 0.0056 0.006 0.006
Brugia malayi Protein kinase domain containing protein 0.0056 0.006 0.006
Leishmania major alpha tubulin 0.003 0.0009 0.0639
Trichomonas vaginalis centaurin beta, putative 0.0076 0.0098 0.0571
Echinococcus multilocularis axis inhibition protein axin 0.0824 0.1579 0.1886
Loa Loa (eye worm) TK/FER protein kinase 0.0056 0.006 0.006
Echinococcus granulosus tyrosine protein kinase pr2 0.0056 0.006 0.0072
Echinococcus multilocularis macrophage colony stimulating factor 1 receptor 0.0056 0.006 0.0072
Loa Loa (eye worm) hypothetical protein 0.0032 0.0011 0.0011
Trypanosoma brucei Flagellum attachment zone protein 20 0.0056 0.006 0.3952
Entamoeba histolytica protein kinase domain containing protein 0.0056 0.006 0.0327
Echinococcus multilocularis raf serine:threonine protein kinase 0.0056 0.006 0.0072
Echinococcus granulosus G protein coupled receptor kinase 1 0.3072 0.6024 0.7196
Toxoplasma gondii beta-1 tubulin, putative 0.0038 0.0024 0.1716
Trichomonas vaginalis TKL family protein kinase 0.0056 0.006 0.0327
Schistosoma mansoni tyrosine kinase 0.0056 0.006 0.006
Echinococcus multilocularis protein KINase family member (kin 25) 0.0056 0.006 0.0072
Plasmodium falciparum conserved Plasmodium protein, unknown function 0.0076 0.0098 0.7102
Schistosoma mansoni Neurotrimin precursor (hNT) 0.0096 0.0139 0.0139
Brugia malayi Protein kinase domain containing protein 0.0056 0.006 0.006
Trypanosoma brucei serine/threonine-protein kinase NRKB, putative 0.0096 0.0139 1
Loa Loa (eye worm) TK/FER protein kinase 0.0056 0.006 0.006
Echinococcus multilocularis atrial natriuretic peptide receptor 1 0.0056 0.006 0.0072
Loa Loa (eye worm) TK protein kinase 0.0056 0.006 0.006
Echinococcus multilocularis tubulin alpha chain 0.003 0.0009 0.0011
Trichomonas vaginalis AGC family protein kinase 0.0096 0.0139 0.0827
Echinococcus granulosus potassium voltage gated channel subfamily H 0.0042 0.0031 0.0037
Schistosoma mansoni ephrin receptor 0.0056 0.006 0.006
Echinococcus granulosus MAM 0.0032 0.0011 0.0013
Entamoeba histolytica receptor protein kinase, putative 0.0056 0.006 0.0327
Echinococcus granulosus macrophage colony stimulating factor 1 receptor 0.0056 0.006 0.0072
Entamoeba histolytica tyrosine kinase, putative 0.0056 0.006 0.0327
Schistosoma mansoni hypothetical protein 0.0168 0.028 0.028
Trypanosoma cruzi PH domain containing protein, putative 0.0076 0.0098 0.6904
Entamoeba histolytica protein tyrosine kinase domain-containing protein 0.0056 0.006 0.0327
Brugia malayi Protein kinase domain containing protein 0.0056 0.006 0.006
Echinococcus multilocularis beta adrenergic receptor kinase 0.3896 0.7653 0.9143
Trichomonas vaginalis TKL family protein kinase 0.0056 0.006 0.0327
Trypanosoma brucei PH domain containing protein, putative 0.0076 0.0098 0.6904
Loa Loa (eye worm) hypothetical protein 0.0032 0.0011 0.0011
Schistosoma mansoni plexin 0.0519 0.0976 0.0976
Echinococcus granulosus tubulin alpha 3 chain 0.003 0.0009 0.0011
Entamoeba histolytica protein kinase, putative 0.0056 0.006 0.0327
Schistosoma mansoni tubulin subunit beta 0.0038 0.0024 0.0024
Loa Loa (eye worm) hypothetical protein 0.0519 0.0976 0.0976
Echinococcus granulosus axis inhibition protein axin 0.0824 0.1579 0.1886
Brugia malayi PH domain containing protein 0.0076 0.0098 0.0098
Entamoeba histolytica hypothetical protein 0.0168 0.028 0.173
Entamoeba histolytica hypothetical protein 0.0056 0.006 0.0327
Brugia malayi Tubulin alpha-2 chain 0.003 0.0009 0.0009
Trypanosoma cruzi serine/threonine-protein kinase NRKB, putative 0.0096 0.0139 1
Echinococcus granulosus tubulin subunit TubB 0.003 0.0009 0.0011
Brugia malayi Sema domain containing protein 0.0383 0.0706 0.0706
Echinococcus granulosus roundabout 2 0.0101 0.0149 0.0178
Entamoeba histolytica protein kinase domain containing protein 0.0056 0.006 0.0327
Plasmodium falciparum tyrosine kinase-like protein 0.0056 0.006 0.4338
Entamoeba histolytica hypothetical protein 0.0096 0.0139 0.0827
Echinococcus multilocularis myotubularin protein 13 0.0076 0.0098 0.0118
Trichomonas vaginalis conserved hypothetical protein 0.0076 0.0098 0.0571
Trypanosoma cruzi rac serine-threonine kinase, putative 0.0096 0.0139 1
Loa Loa (eye worm) hypothetical protein 0.0383 0.0706 0.0706
Echinococcus multilocularis tyrosine protein kinase Abl 0.0056 0.006 0.0072
Giardia lamblia Beta tubulin 0.0038 0.0024 0.149
Echinococcus granulosus oxysterol binding protein 1 0.0076 0.0098 0.0118
Loa Loa (eye worm) hypothetical protein 0.0056 0.006 0.006
Schistosoma mansoni tyrosine kinase 0.0056 0.006 0.006
Brugia malayi hypothetical protein 0.0076 0.0098 0.0098
Echinococcus granulosus tubulin alpha chain 0.003 0.0009 0.0011
Loa Loa (eye worm) TK protein kinase 0.0056 0.006 0.006
Schistosoma mansoni syntrophin 0.0076 0.0098 0.0098
Echinococcus multilocularis oxysterol binding protein 9 0.0076 0.0098 0.0118
Trichomonas vaginalis conserved hypothetical protein 0.0076 0.0098 0.0571
Giardia lamblia Kinase, NEK 0.0056 0.006 0.5116
Trichomonas vaginalis TKL family protein kinase 0.0056 0.006 0.0327
Trypanosoma cruzi Serine/threonine-protein kinase NEK17, putative 0.0096 0.0139 1
Echinococcus multilocularis beta 1 syntrophin 0.0076 0.0098 0.0118
Trichomonas vaginalis AGC family protein kinase 0.0096 0.0139 0.0827
Loa Loa (eye worm) syntrophin-1 0.0076 0.0098 0.0098
Trichomonas vaginalis TKL family protein kinase 0.0056 0.006 0.0327
Echinococcus granulosus beta tubulin 0.0038 0.0024 0.0028
Entamoeba histolytica protein kinase domain containing protein 0.0056 0.006 0.0327
Brugia malayi Furin-like cysteine rich region family protein 0.0056 0.006 0.006
Schistosoma mansoni voltage-gated potassium channel 0.0045 0.0039 0.0039
Loa Loa (eye worm) RGS-3 protein 0.0824 0.1579 0.1579
Echinococcus granulosus twitchin 0.0116 0.0179 0.0214
Loa Loa (eye worm) hypothetical protein 0.0076 0.0098 0.0098
Echinococcus multilocularis epidermal growth factor receptor 0.0056 0.006 0.0072
Trypanosoma cruzi rac serine-threonine kinase, putative 0.0096 0.0139 1
Schistosoma mansoni dynamin 0.0076 0.0098 0.0098
Entamoeba histolytica tyrosine kinase, putative 0.0056 0.006 0.0327
Loa Loa (eye worm) oxysterol binding protein 0.0076 0.0098 0.0098
Echinococcus multilocularis tyrosine kinase 0.0056 0.006 0.0072
Loa Loa (eye worm) sema domain-containing protein 0.0383 0.0706 0.0706
Entamoeba histolytica ankyrin repeat protein 0.0056 0.006 0.0327
Trichomonas vaginalis AGC family protein kinase 0.0096 0.0139 0.0827
Trichomonas vaginalis AGC family protein kinase 0.0096 0.0139 0.0827
Brugia malayi Oxysterol binding protein 0.0076 0.0098 0.0098
Loa Loa (eye worm) hypothetical protein 0.0096 0.0139 0.0139
Loa Loa (eye worm) hypothetical protein 0.0076 0.0098 0.0098
Onchocerca volvulus 0.0056 0.006 0.0284
Loa Loa (eye worm) hypothetical protein 0.0232 0.0407 0.0407
Brugia malayi Tubulin alpha chain 0.003 0.0009 0.0009
Schistosoma mansoni tyrosine kinase 0.0056 0.006 0.006
Trypanosoma cruzi PH domain containing protein, putative 0.0076 0.0098 0.6904
Schistosoma mansoni protein kinase 0.0056 0.006 0.006
Echinococcus granulosus Tubulin beta 2C chain 0.0038 0.0024 0.0028
Trichomonas vaginalis TKL family protein kinase 0.0056 0.006 0.0327
Trichomonas vaginalis conserved hypothetical protein 0.0076 0.0098 0.0571
Brugia malayi GTP-ase activating protein for Arf containing protein 0.0076 0.0098 0.0098
Brugia malayi hypothetical protein 0.0383 0.0706 0.0706
Schistosoma mansoni regulator of G protein signaling 0.0824 0.1579 0.1579
Entamoeba histolytica protein kinase domain containing protein 0.0056 0.006 0.0327
Echinococcus multilocularis cytohesin 1 0.0076 0.0098 0.0118
Trichomonas vaginalis conserved hypothetical protein 0.0056 0.006 0.0327
Loa Loa (eye worm) hypothetical protein 0.0168 0.028 0.028
Echinococcus multilocularis tyrosine protein kinase ABL1 0.0056 0.006 0.0072
Echinococcus granulosus tubulin alpha chain 0.003 0.0009 0.0011
Trichomonas vaginalis Clan MA, family M8, leishmanolysin-like metallopeptidase 0.0168 0.028 0.173
Trichomonas vaginalis serine/threonine-protein kinase wnk, putative 0.0056 0.006 0.0327
Trichomonas vaginalis AGC family protein kinase 0.0096 0.0139 0.0827
Trypanosoma brucei serine/threonine-protein kinase NrkA 0.0096 0.0139 1
Brugia malayi integrin-linked kinase 0.0056 0.006 0.006
Echinococcus granulosus A kinase anchor protein 10 mitochondrial 0.0824 0.1579 0.1886
Loa Loa (eye worm) tubulin alpha chain 0.003 0.0009 0.0009
Echinococcus granulosus Pleckstrin y 0.0076 0.0098 0.0118
Trichomonas vaginalis tubulin gamma chain, putative 0.0038 0.0024 0.0095
Entamoeba histolytica protein kinase, putative 0.0056 0.006 0.0327
Schistosoma mansoni protein kinase 0.0081 0.0109 0.0109
Trichomonas vaginalis conserved hypothetical protein 0.0168 0.028 0.173
Entamoeba histolytica tyrosine kinase, putative 0.0056 0.006 0.0327
Loa Loa (eye worm) uncoordinated protein 104 0.0076 0.0098 0.0098
Loa Loa (eye worm) hypothetical protein 0.0168 0.028 0.028
Trypanosoma cruzi aurora B kinase, putative 0.0081 0.0109 0.7725
Trichomonas vaginalis AGC family protein kinase 0.0096 0.0139 0.0827
Entamoeba histolytica hypothetical protein 0.0056 0.006 0.0327
Brugia malayi Protein kinase domain containing protein 0.0056 0.006 0.006
Loa Loa (eye worm) hypothetical protein 0.0824 0.1579 0.1579
Echinococcus multilocularis tubulin alpha 3 chain 0.003 0.0009 0.0011
Entamoeba histolytica Rho guanine nucleotide exchange factor, putative 0.0076 0.0098 0.0571
Echinococcus multilocularis tubulin alpha 1C chain 0.003 0.0009 0.0011
Loa Loa (eye worm) AGC/GRK/BARK protein kinase 0.3896 0.7653 0.7653
Echinococcus granulosus type II inositol 34 bisphosphate 4 phosphatase 0.0076 0.0098 0.0118
Loa Loa (eye worm) hypothetical protein 0.0076 0.0098 0.0098
Leishmania major beta tubulin 0.0038 0.0024 0.1716
Echinococcus multilocularis kinase suppressor of Ras 1 0.0056 0.006 0.0072
Trichomonas vaginalis conserved hypothetical protein 0.0076 0.0098 0.0571
Entamoeba histolytica pleckstrin homology (PH) domain containing protein 0.0076 0.0098 0.0571
Entamoeba histolytica protein kinase, putative 0.0056 0.006 0.0327
Trichomonas vaginalis conserved hypothetical protein 0.0076 0.0098 0.0571
Giardia lamblia Beta tubulin 0.0038 0.0024 0.149
Leishmania major beta tubulin 0.0038 0.0024 0.1716
Onchocerca volvulus Abnormal cell migration protein 10 homolog 0.0076 0.0098 0.0506
Loa Loa (eye worm) TKL/MLK/ILK protein kinase 0.0056 0.006 0.006
Entamoeba histolytica hypothetical protein 0.0076 0.0098 0.0571
Brugia malayi tubulin alpha-2 chain 0.003 0.0009 0.0009
Trichomonas vaginalis conserved hypothetical protein 0.0076 0.0098 0.0571
Entamoeba histolytica protein kinase domain containing protein 0.0056 0.006 0.0327
Trypanosoma cruzi hypothetical protein 0.0076 0.0098 0.6904
Entamoeba histolytica protein tyrosine kinase domain-containing protein 0.0056 0.006 0.0327
Toxoplasma gondii hypothetical protein 0.0076 0.0098 0.7102
Trichomonas vaginalis AGC family protein kinase 0.0096 0.0139 0.0827
Entamoeba histolytica PH domain containing protein 0.0076 0.0098 0.0571
Toxoplasma gondii STE kinase 0.0056 0.006 0.4338
Echinococcus granulosus regulator of G protein signaling 7 0.0824 0.1579 0.1886
Echinococcus multilocularis serine:threonine protein kinase 12 B 0.0081 0.0109 0.013
Trichomonas vaginalis tubulin epsilon chain, putative 0.0038 0.0024 0.0095
Leishmania major hypothetical protein, conserved 0.0076 0.0098 0.7102
Echinococcus multilocularis tyrosine protein kinase Fes:Fps 0.0056 0.006 0.0072
Trichomonas vaginalis AGC family protein kinase 0.0096 0.0139 0.0827
Schistosoma mansoni regulator of G protein signaling 0.0824 0.1579 0.1579
Entamoeba histolytica PH domain containing protein kinase, putative 0.0096 0.0139 0.0827
Brugia malayi Probable G protein-coupled receptor kinase F19C6.1, putative 0.4259 0.837 0.837
Trichomonas vaginalis TKL family protein kinase 0.0056 0.006 0.0327
Echinococcus multilocularis activated cdc42 kinase 1 0.0056 0.006 0.0072
Trichomonas vaginalis conserved hypothetical protein 0.0824 0.1579 1
Trichomonas vaginalis TKL family protein kinase 0.0056 0.006 0.0327
Echinococcus granulosus tyrosine protein kinase 0.0056 0.006 0.0072
Plasmodium vivax protein kinase, putative 0.0056 0.006 0.3952
Echinococcus granulosus neuroglian 0.0096 0.0139 0.0166
Entamoeba histolytica hypothetical protein 0.0824 0.1579 1
Brugia malayi Tubulin beta-1 chain 0.0038 0.0024 0.0024
Schistosoma mansoni hypothetical protein 0.0076 0.0098 0.0098
Entamoeba histolytica protein tyrosine kinase domain-containing protein 0.0056 0.006 0.0327
Loa Loa (eye worm) RhoGEF domain-containing protein 0.0076 0.0098 0.0098
Trypanosoma cruzi NEK family Serine/threonine-protein kinase, putative 0.0076 0.0098 0.6904
Entamoeba histolytica hypothetical protein, conserved 0.0056 0.006 0.0327
Echinococcus multilocularis semaphorin 5B 0.0383 0.0706 0.0843
Leishmania major beta tubulin 0.0038 0.0024 0.1716
Trichomonas vaginalis regulator of G protein signaling 5, rgs5, putative 0.0824 0.1579 1
Giardia lamblia Protein 21.1 0.0056 0.006 0.5116
Leishmania major rac serine-threonine kinase, putative,protein kinase, putative 0.0096 0.0139 1
Echinococcus granulosus integrin linked protein kinase 0.0056 0.006 0.0072
Echinococcus multilocularis tyrosine protein kinase Srms 0.0056 0.006 0.0072
Loa Loa (eye worm) hypothetical protein 0.0076 0.0098 0.0098
Brugia malayi Protein kinase domain containing protein 0.0056 0.006 0.006
Echinococcus multilocularis oxysterol binding protein 3 0.0076 0.0098 0.0118
Schistosoma mansoni protein kinase 0.0077 0.01 0.01
Echinococcus granulosus tubulin alpha chain 0.003 0.0009 0.0011
Entamoeba histolytica serine/threonine kinase, putative 0.0056 0.006 0.0327
Echinococcus granulosus Tubulin beta 2C chain 0.0038 0.0024 0.0028
Loa Loa (eye worm) serine/threonine protein kinase 0.0056 0.006 0.006
Loa Loa (eye worm) TKL/MLK/TAK1 protein kinase 0.0056 0.006 0.006
Trypanosoma brucei Pseudokinase, putative 0.0056 0.006 0.3952
Echinococcus multilocularis Tubulin alpha 1 chain 0.003 0.0009 0.0011
Brugia malayi PH domain containing protein 0.0076 0.0098 0.0098
Echinococcus multilocularis G protein coupled receptor kinase 6 0.4259 0.837 1
Loa Loa (eye worm) TK/FER protein kinase 0.0056 0.006 0.006
Entamoeba histolytica hypothetical protein 0.0056 0.006 0.0327
Echinococcus multilocularis insulin growth factor 1 receptor beta 0.0061 0.007 0.0084
Trichomonas vaginalis TKL family protein kinase 0.0056 0.006 0.0327
Leishmania major hypothetical protein, conserved 0.0056 0.006 0.4338
Trichomonas vaginalis AGC family protein kinase 0.0096 0.0139 0.0827
Echinococcus multilocularis epidermal growth factor receptor 0.0056 0.006 0.0072
Echinococcus granulosus raf serine:threonine protein kinase 0.0056 0.006 0.0072
Plasmodium vivax tyrosine kinase-like protein, putative 0.0056 0.006 0.3952
Trichomonas vaginalis conserved hypothetical protein 0.0824 0.1579 1
Entamoeba histolytica protein kinase, putative 0.0056 0.006 0.0327
Entamoeba histolytica protein kinase, putative 0.0081 0.0109 0.0639
Loa Loa (eye worm) hypothetical protein 0.0056 0.006 0.006
Onchocerca volvulus 0.0076 0.0098 0.0506
Brugia malayi Immunoglobulin I-set domain containing protein 0.0101 0.0149 0.0149
Trypanosoma cruzi phosphatidylinositol-4-phosphate 5-kinase, putative 0.0076 0.0098 0.6904
Echinococcus granulosus Arf GAP and Pleckstrin domain containing protein 0.0076 0.0098 0.0118
Loa Loa (eye worm) TKL/STKR/TYPE1 protein kinase 0.0056 0.006 0.006
Schistosoma mansoni src-type protein tyrosine kinase-related 0.0056 0.006 0.006
Trichomonas vaginalis ankyrin 2,3/unc44, putative 0.0076 0.0098 0.0571
Loa Loa (eye worm) TK protein kinase 0.0056 0.006 0.006
Trichomonas vaginalis CAMK family protein kinase 0.0056 0.006 0.0327
Schistosoma mansoni tyrosine kinase 0.0056 0.006 0.006
Trichomonas vaginalis TKL family protein kinase 0.0056 0.006 0.0327
Loa Loa (eye worm) PXA domain-containing protein 0.0824 0.1579 0.1579
Schistosoma mansoni growth factor receptor-bound protein 0.0076 0.0098 0.0098
Trichomonas vaginalis centaurin/arf, putative 0.0076 0.0098 0.0571
Entamoeba histolytica hypothetical protein 0.0056 0.006 0.0327
Echinococcus granulosus Tubulin alpha 1 chain 0.003 0.0009 0.0011
Schistosoma mansoni cell adhesion molecule 0.0101 0.0149 0.0149
Echinococcus multilocularis tyrosine protein kinase Blk 0.0056 0.006 0.0072
Echinococcus granulosus mitogen activated protein kinase kinase kinase 0.0056 0.006 0.0072
Loa Loa (eye worm) TK/FER protein kinase 0.0056 0.006 0.006
Entamoeba histolytica hypothetical protein 0.0056 0.006 0.0327
Trypanosoma brucei NEK family Serine/threonine-protein kinase, putative 0.0096 0.0139 1
Loa Loa (eye worm) hypothetical protein 0.0076 0.0098 0.0098
Echinococcus multilocularis rac serine:threonine kinase 0.0096 0.0139 0.0166
Entamoeba histolytica tyrosine kinase, putative 0.0056 0.006 0.0327
Brugia malayi hypothetical protein 0.0824 0.1579 0.1579
Loa Loa (eye worm) hypothetical protein 0.0096 0.0139 0.0139
Trichomonas vaginalis TKL family protein kinase 0.0056 0.006 0.0327
Echinococcus granulosus receptor type guanylyl cyclase 0.0056 0.006 0.0072
Schistosoma mansoni tubulin subunit beta 0.0038 0.0024 0.0024
Trichomonas vaginalis conserved hypothetical protein 0.0076 0.0098 0.0571
Brugia malayi Protein kinase domain containing protein 0.0056 0.006 0.006
Echinococcus multilocularis exocyst complex component 2 0.0168 0.028 0.0335
Onchocerca volvulus 0.0056 0.006 0.0284
Trichomonas vaginalis TKL family protein kinase 0.0056 0.006 0.0327
Trichomonas vaginalis ankyrin repeat and FYVE domain containing protein, putative 0.0076 0.0098 0.0571
Loa Loa (eye worm) G protein signaling regulator EGL-10 0.0824 0.1579 0.1579
Loa Loa (eye worm) alpha-tubulin 0.003 0.0009 0.0009
Loa Loa (eye worm) TK/ABL protein kinase 0.0056 0.006 0.006
Schistosoma mansoni protein kinase 0.0056 0.006 0.006
Toxoplasma gondii alpha tubulin TUBA1 0.003 0.0009 0.0639
Brugia malayi Immunoglobulin I-set domain containing protein 0.0152 0.025 0.025
Trichomonas vaginalis TKL family protein kinase 0.0056 0.006 0.0327
Trichomonas vaginalis alpha chimerin, putative 0.0076 0.0098 0.0571
Echinococcus multilocularis actin binding protein anillin 0.0076 0.0098 0.0118
Brugia malayi C-terminal src kinase protein 1 0.0056 0.006 0.006
Echinococcus multilocularis tubulin alpha chain 0.003 0.0009 0.0011
Echinococcus granulosus oxysterol binding protein 3 0.0076 0.0098 0.0118
Schistosoma mansoni tyrosine kinase 0.0056 0.006 0.006
Entamoeba histolytica tyrosine- protein kinase 2, putative 0.0056 0.006 0.0327
Trypanosoma brucei Serine/threonine-protein kinase NEK21, putative 0.0096 0.0139 1
Toxoplasma gondii protein kinase domain-containing protein 0.0096 0.0139 1
Echinococcus granulosus Tubulin alpha 1 chain 0.003 0.0009 0.0011
Brugia malayi Pleckstrin Homology Domain 0.0076 0.0098 0.0098
Echinococcus granulosus beta-adrenergic receptor kinase 0.3896 0.7653 0.9143
Brugia malayi SRC-1 0.0056 0.006 0.006
Toxoplasma gondii phosphatidylinositol transfer protein 0.0076 0.0098 0.7102
Entamoeba histolytica protein tyrosine kinase domain-containing protein 0.0056 0.006 0.0327
Echinococcus granulosus insulin growth factor 1 receptor beta 0.0061 0.007 0.0084
Trichomonas vaginalis TKL family protein kinase 0.0056 0.006 0.0327
Trichomonas vaginalis AGC family protein kinase 0.0096 0.0139 0.0827
Schistosoma mansoni hypothetical protein 0.0076 0.0098 0.0098
Toxoplasma gondii hypothetical protein 0.0076 0.0098 0.7102
Loa Loa (eye worm) TK/FER protein kinase 0.0056 0.006 0.006
Brugia malayi Protein kinase domain containing protein 0.0056 0.006 0.006
Loa Loa (eye worm) hypothetical protein 0.0056 0.006 0.006
Loa Loa (eye worm) TK protein kinase 0.0056 0.006 0.006
Brugia malayi Protein kinase domain containing protein 0.0056 0.006 0.006
Loa Loa (eye worm) BEN-1 protein 0.0038 0.0024 0.0024
Schistosoma mansoni vesicular amine transporter 0.0099 0.0144 0.0144
Schistosoma mansoni tyrosine kinase 0.0056 0.006 0.006
Leishmania major beta tubulin 0.0038 0.0024 0.1716
Brugia malayi hypothetical protein 0.0032 0.0011 0.0011
Schistosoma mansoni tyrosine kinase 0.0056 0.006 0.006
Schistosoma mansoni tyrosine kinase 0.0056 0.006 0.006
Entamoeba histolytica SH2-protein kinase domain containing protein 0.0056 0.006 0.0327
Trypanosoma cruzi hypothetical protein 0.0076 0.0098 0.6904
Echinococcus granulosus tubulin beta 1 chain 0.0038 0.0024 0.0028
Entamoeba histolytica protein kinase, putative 0.0056 0.006 0.0327
Entamoeba histolytica protein kinase domain containing protein 0.0056 0.006 0.0327
Leishmania major beta tubulin 0.0038 0.0024 0.1716
Entamoeba histolytica Rho guanine nucleotide exchange factor, putative 0.0076 0.0098 0.0571
Schistosoma mansoni serine/threonine RGC 0.0056 0.006 0.006
Trichomonas vaginalis TKL family protein kinase 0.0056 0.006 0.0327
Schistosoma mansoni tubulin subunit alpha 0.003 0.0009 0.0009
Entamoeba histolytica ARF GTPase activating protein, putative 0.0076 0.0098 0.0571
Schistosoma mansoni tyrosine kinase 0.0056 0.006 0.006
Entamoeba histolytica receptor protein kinase, putative 0.0056 0.006 0.0327
Echinococcus granulosus tyrosine protein kinase Src64B 0.0056 0.006 0.0072
Entamoeba histolytica hypothetical protein 0.0076 0.0098 0.0571
Echinococcus multilocularis protein kinase 0.0056 0.006 0.0072
Loa Loa (eye worm) hypothetical protein 0.0383 0.0706 0.0706
Entamoeba histolytica protein kinase, putative 0.0096 0.0139 0.0827
Brugia malayi regulator of G-protein signaling egl-10 0.0824 0.1579 0.1579
Leishmania major alpha tubulin 0.003 0.0009 0.0639
Echinococcus multilocularis tubulin beta 1 chain 0.0038 0.0024 0.0028
Entamoeba histolytica protein kinase domain containing protein 0.0056 0.006 0.0327
Trypanosoma cruzi protein kinase, putative 0.0056 0.006 0.3952
Schistosoma mansoni protein kinase 0.0077 0.01 0.01
Trypanosoma cruzi Protein kinase B 0.0096 0.0139 1
Brugia malayi Tyrosine-protein kinase F09A5.2 in chromosome X, putative 0.0056 0.006 0.006
Echinococcus multilocularis tyrosine protein kinase Src64B 0.0056 0.006 0.0072
Echinococcus granulosus tyrosine protein kinase Btk29A 0.0056 0.006 0.0072
Entamoeba histolytica hypothetical protein, conserved 0.0076 0.0098 0.0571
Entamoeba histolytica serine/threonine protein kinase 6, putative 0.0081 0.0109 0.0639
Brugia malayi Dynamin 0.0076 0.0098 0.0098
Trypanosoma cruzi Serine/threonine-protein kinase NEK17, putative 0.0096 0.0139 1
Brugia malayi Protein kinase domain containing protein 0.0056 0.006 0.006
Echinococcus multilocularis integrin linked protein kinase 0.0056 0.006 0.0072
Entamoeba histolytica PH domain containing protein 0.0076 0.0098 0.0571
Brugia malayi Dynamin 0.0076 0.0098 0.0098
Toxoplasma gondii beta tubulin 0.0038 0.0024 0.1716
Schistosoma mansoni tyrosine kinase 0.0056 0.006 0.006
Leishmania major hypothetical protein, conserved 0.0076 0.0098 0.7102
Brugia malayi Tyrosine-protein kinase abl-1 0.0056 0.006 0.006
Trichomonas vaginalis TKL family protein kinase 0.0056 0.006 0.0327
Giardia lamblia Kinase, NEK 0.0056 0.006 0.5116
Trichomonas vaginalis TKL family protein kinase 0.0056 0.006 0.0327
Echinococcus granulosus tyrosine protein kinase shark 0.0056 0.006 0.0072
Loa Loa (eye worm) TK protein kinase 0.0056 0.006 0.006
Schistosoma mansoni oxysterol-binding protein 1 0.0076 0.0098 0.0098
Loa Loa (eye worm) hypothetical protein 0.0056 0.006 0.006
Loa Loa (eye worm) TK protein kinase 0.0056 0.006 0.006
Echinococcus multilocularis tubulin alpha chain 0.003 0.0009 0.0011
Echinococcus multilocularis beta tubulin 0.0038 0.0024 0.0028
Schistosoma mansoni serine/threonine protein kinase 0.0081 0.0109 0.0109
Loa Loa (eye worm) hypothetical protein 0.0076 0.0098 0.0098
Brugia malayi hypothetical protein 0.0056 0.006 0.006
Entamoeba histolytica hypothetical protein, conserved domain containing 0.0076 0.0098 0.0571
Entamoeba histolytica PH domain containing protein kinase, putative 0.0096 0.0139 0.0827
Loa Loa (eye worm) hypothetical protein 0.0096 0.0139 0.0139
Entamoeba histolytica Rho guanine nucleotide exchange factor, putative 0.0076 0.0098 0.0571
Brugia malayi Uncoordinated protein 104 0.0076 0.0098 0.0098
Entamoeba histolytica protein kinase, putative 0.0056 0.006 0.0327
Schistosoma mansoni regulator of G protein signaling 17 19 20 (rgs17 19 20) 0.0824 0.1579 0.1579
Schistosoma mansoni tubulin subunit beta 0.0038 0.0024 0.0024
Trichomonas vaginalis Clan MA, family M8, leishmanolysin-like metallopeptidase 0.0168 0.028 0.173
Entamoeba histolytica serine/threonine kinase, putative 0.0056 0.006 0.0327
Echinococcus multilocularis c src tyrosine kinase 0.0056 0.006 0.0072
Loa Loa (eye worm) Plekhf2 protein 0.0076 0.0098 0.0098
Loa Loa (eye worm) hypothetical protein 0.003 0.0009 0.0009
Echinococcus multilocularis regulator of G protein signaling 0.0824 0.1579 0.1886
Entamoeba histolytica hypothetical protein 0.0168 0.028 0.173
Trichomonas vaginalis AGC family protein kinase 0.0096 0.0139 0.0827
Echinococcus multilocularis tyrosine protein kinase csk 0.0056 0.006 0.0072
Brugia malayi Adenylate and Guanylate cyclase catalytic domain containing protein 0.0056 0.006 0.006
Echinococcus multilocularis hypothetical protein 0.0383 0.0706 0.0843
Entamoeba histolytica tyrosine kinase, putative 0.0056 0.006 0.0327
Echinococcus granulosus Tubulin beta 2C chain 0.0038 0.0024 0.0028
Echinococcus granulosus tyrosine protein kinase Lyn 0.0077 0.01 0.012
Brugia malayi Sema domain containing protein 0.0383 0.0706 0.0706
Loa Loa (eye worm) TK/EPH protein kinase 0.0056 0.006 0.006
Echinococcus granulosus FERM and pleckstrin domain containing protein 0.0076 0.0098 0.0118
Trichomonas vaginalis conserved hypothetical protein 0.0076 0.0098 0.0571
Brugia malayi GTP-ase activating protein for Arf containing protein 0.0076 0.0098 0.0098
Echinococcus granulosus tubulin alpha 1C chain 0.003 0.0009 0.0011
Echinococcus multilocularis neuroglian 0.0096 0.0139 0.0166
Schistosoma mansoni serine/threonine protein kinase 0.3896 0.7653 0.7653
Trichomonas vaginalis TKL family protein kinase 0.0056 0.006 0.0327
Onchocerca volvulus 0.0056 0.006 0.0284
Plasmodium vivax tubulin beta chain, putative 0.0038 0.0024 0.1151
Brugia malayi hypothetical protein 0.0383 0.0706 0.0706
Loa Loa (eye worm) hypothetical protein 0.0383 0.0706 0.0706
Leishmania major beta tubulin 0.0038 0.0024 0.1716
Trichomonas vaginalis conserved hypothetical protein 0.0076 0.0098 0.0571
Brugia malayi Protein kinase domain containing protein 0.0056 0.006 0.006
Trichomonas vaginalis TKL family protein kinase 0.0056 0.006 0.0327
Toxoplasma gondii calcium dependent protein kinase CDPK8 0.0077 0.01 0.7236
Trypanosoma brucei beta tubulin 0.0038 0.0024 0.1151
Entamoeba histolytica tyrosine kinase, putative 0.0056 0.006 0.0327
Trichomonas vaginalis AGC family protein kinase 0.0096 0.0139 0.0827
Echinococcus granulosus activin receptor type 0.0077 0.01 0.012
Echinococcus granulosus tyrosine protein kinase Src42A 0.0056 0.006 0.0072
Brugia malayi Immunoglobulin I-set domain containing protein 0.0056 0.006 0.006
Trichomonas vaginalis conserved hypothetical protein 0.0168 0.028 0.173
Echinococcus multilocularis tubulin subunit TubB 0.003 0.0009 0.0011
Echinococcus granulosus calcium dependent secretion activator 1 0.0076 0.0098 0.0118
Entamoeba histolytica tyrosin kinase, putative 0.0224 0.0392 0.2438
Schistosoma mansoni regulator of G protein signaling 17 19 20 (rgs17 19 20) 0.0824 0.1579 0.1579
Trichomonas vaginalis conserved hypothetical protein 0.0076 0.0098 0.0571
Leishmania major protein kinase, putative,serine/threonine protein kinase, putative 0.0096 0.0139 1
Brugia malayi Protein kinase domain containing protein 0.0096 0.0139 0.0139
Echinococcus multilocularis tubulin alpha chain 0.003 0.0009 0.0011
Echinococcus multilocularis pdz domain containing protein 0.0076 0.0098 0.0118
Echinococcus multilocularis Tubulin beta 2C chain 0.0038 0.0024 0.0028
Entamoeba histolytica protein kinase, putative 0.0056 0.006 0.0327
Leishmania major alpha tubulin 0.003 0.0009 0.0639
Echinococcus granulosus tyrosine protein kinase HCK 0.0056 0.006 0.0072
Echinococcus multilocularis tyrosine protein kinase Src42A 0.0056 0.006 0.0072
Trypanosoma cruzi PH domain containing protein, putative 0.0076 0.0098 0.6904
Echinococcus multilocularis roundabout 2 0.0101 0.0149 0.0178
Trichomonas vaginalis AGC family protein kinase 0.0096 0.0139 0.0827
Entamoeba histolytica tyrosine kinase, putative 0.0056 0.006 0.0327
Trichomonas vaginalis TKL family protein kinase 0.0056 0.006 0.0327
Loa Loa (eye worm) hypothetical protein 0.0056 0.006 0.006
Loa Loa (eye worm) TK/FER protein kinase 0.0056 0.006 0.006
Entamoeba histolytica serine/threonine kinase, putative 0.0056 0.006 0.0327
Onchocerca volvulus 0.0056 0.006 0.0284
Echinococcus granulosus tyrosine protein kinase Btk29A 0.0056 0.006 0.0072
Entamoeba histolytica protein kinase domain containing protein 0.0056 0.006 0.0327
Trichomonas vaginalis AGC family protein kinase 0.0096 0.0139 0.0827
Echinococcus multilocularis ephrin type A receptor 4 A 0.0056 0.006 0.0072
Schistosoma mansoni serine/threonine protein kinase 0.3896 0.7653 0.7653
Trypanosoma cruzi PH domain containing protein, putative 0.0076 0.0098 0.6904
Schistosoma mansoni tyrosine kinase 0.0056 0.006 0.006
Schistosoma mansoni serine/threonine-protein kinase 0.0096 0.0139 0.0139
Echinococcus multilocularis expressed protein 0.0824 0.1579 0.1886
Brugia malayi Adenylate and Guanylate cyclase catalytic domain containing protein 0.0056 0.006 0.006
Echinococcus multilocularis tyrosine protein kinase csk 0.0056 0.006 0.0072
Brugia malayi hypothetical protein 0.0056 0.006 0.006
Trichomonas vaginalis TKL family protein kinase 0.0056 0.006 0.0327
Echinococcus granulosus expressed protein 0.0824 0.1579 0.1886
Trichomonas vaginalis TKL family protein kinase 0.0056 0.006 0.0327
Brugia malayi PXA domain containing protein 0.0824 0.1579 0.1579
Loa Loa (eye worm) SRC-1 0.0056 0.006 0.006
Loa Loa (eye worm) AUR protein kinase 0.0081 0.0109 0.0109
Trichomonas vaginalis conserved hypothetical protein 0.0056 0.006 0.0327
Entamoeba histolytica protein kinase with ankyrin repeats, putative 0.0056 0.006 0.0327
Plasmodium falciparum alpha tubulin 1 0.003 0.0009 0.0639
Trypanosoma brucei aurora B kinase 0.0081 0.0109 0.7725
Entamoeba histolytica protein kinase, putative 0.0056 0.006 0.0327
Schistosoma mansoni guanyl-nucleotide exchange factor 0.0076 0.0098 0.0098
Entamoeba histolytica tyrosine kinase, putative 0.0056 0.006 0.0327
Schistosoma mansoni centaurin alpha 0.0076 0.0098 0.0098
Echinococcus multilocularis transfer RNA-Thr 0.0056 0.006 0.0072
Schistosoma mansoni nephrin 0.0101 0.0149 0.0149
Brugia malayi DNA-binding protein LAG-1 0.0168 0.028 0.028
Entamoeba histolytica protein kinase, putative 0.0056 0.006 0.0327
Trichomonas vaginalis Clan MA, family M8, leishmanolysin-like metallopeptidase 0.0168 0.028 0.173
Onchocerca volvulus 0.0056 0.006 0.0284
Loa Loa (eye worm) hypothetical protein 0.0076 0.0098 0.0098
Trichomonas vaginalis AGC family protein kinase 0.0096 0.0139 0.0827
Loa Loa (eye worm) hypothetical protein 0.0076 0.0098 0.0098
Brugia malayi PH domain containing protein 0.0076 0.0098 0.0098
Echinococcus granulosus Regulator of G protein signaling 20 0.0824 0.1579 0.1886
Schistosoma mansoni axis inhibition protein axin 0.0824 0.1579 0.1579
Loa Loa (eye worm) TK/FER protein kinase 0.0056 0.006 0.006
Echinococcus granulosus myotubularin protein 13 0.0076 0.0098 0.0118
Echinococcus granulosus tyrosine protein kinase csk 0.0056 0.006 0.0072
Schistosoma mansoni development and differentiation-enhancing factor ddef 0.0076 0.0098 0.0098
Echinococcus granulosus tubulin alpha 3 chain 0.003 0.0009 0.0011
Echinococcus multilocularis dynamin 1 0.0076 0.0098 0.0118
Trichomonas vaginalis TKL family protein kinase 0.0056 0.006 0.0327
Entamoeba histolytica protein kinase, putative 0.0056 0.006 0.0327
Entamoeba histolytica protein kinase, putative 0.0056 0.006 0.0327
Echinococcus multilocularis Arf GAP and Pleckstrin domain containing protein 0.0076 0.0098 0.0118
Brugia malayi Protein kinase domain containing protein 0.0056 0.006 0.006
Trichomonas vaginalis TKL family protein kinase 0.0056 0.006 0.0327
Schistosoma mansoni tyrosine kinase 0.0056 0.006 0.006
Entamoeba histolytica protein kinase, putative 0.0096 0.0139 0.0827
Brugia malayi proto-oncogene tyrosine-protein kinase FER 0.0056 0.006 0.006
Loa Loa (eye worm) TK/FER protein kinase 0.0056 0.006 0.006
Entamoeba histolytica tyrosin kinase, putative 0.0056 0.006 0.0327
Trichomonas vaginalis AGC family protein kinase 0.0096 0.0139 0.0827
Schistosoma mansoni hypothetical protein 0.0076 0.0098 0.0098
Trichomonas vaginalis TKL family protein kinase 0.0056 0.006 0.0327
Leishmania major beta tubulin 0.0038 0.0024 0.1716
Entamoeba histolytica leucine-rich repeat domain-containing protein 0.0056 0.006 0.0327
Trichomonas vaginalis TKL family protein kinase 0.0056 0.006 0.0327
Brugia malayi Receptor family ligand binding region containing protein 0.0056 0.006 0.006
Brugia malayi Syntrophin-1 0.0076 0.0098 0.0098
Plasmodium vivax hypothetical protein, conserved 0.0076 0.0098 0.6904
Schistosoma mansoni hypothetical protein 0.0032 0.0011 0.0011
Echinococcus granulosus tyrosine protein kinase Fyn 0.0056 0.006 0.0072
Echinococcus multilocularis aurora kinase A 0.0081 0.0109 0.013
Brugia malayi IPT/TIG domain containing protein 0.0168 0.028 0.028
Echinococcus multilocularis plexin a4 0.107 0.2064 0.2466
Echinococcus multilocularis Tubulin beta 2C chain 0.0038 0.0024 0.0028
Entamoeba histolytica protein kinase , putative 0.0081 0.0109 0.0639
Echinococcus granulosus 3'partial|retinal guanylyl cyclase 2 0.0056 0.006 0.0072
Brugia malayi plexin A 0.107 0.2064 0.2064
Echinococcus granulosus regulator of G protein signaling 3 0.0824 0.1579 0.1886
Onchocerca volvulus 0.0383 0.0706 0.4033
Brugia malayi Protein kinase domain containing protein 0.0056 0.006 0.006
Echinococcus granulosus tubulin subunit beta 0.0038 0.0024 0.0028
Toxoplasma gondii beta-tubulin, putative 0.0038 0.0024 0.1716
Schistosoma mansoni protein kinase 0.0077 0.01 0.01
Schistosoma mansoni zinc finger protein 0.0076 0.0098 0.0098
Brugia malayi MAX-1A 0.0076 0.0098 0.0098
Echinococcus multilocularis Tubulin alpha 1 chain 0.003 0.0009 0.0011
Trichomonas vaginalis AGC family protein kinase 0.0081 0.0109 0.0639
Entamoeba histolytica hypothetical protein, conserved domain containing 0.0076 0.0098 0.0571
Echinococcus multilocularis regulator of G protein signaling 7 0.0824 0.1579 0.1886
Schistosoma mansoni goodpasture antigen-binding protein 0.0076 0.0098 0.0098
Echinococcus granulosus regulator of G protein signaling 3 0.0824 0.1579 0.1886
Entamoeba histolytica protein tyrosine kinase domain-containing protein 0.0056 0.006 0.0327
Schistosoma mansoni protein kinase 0.0056 0.006 0.006
Schistosoma mansoni proto-oncogene tyrosine-protein kinase src 0.0056 0.006 0.006
Echinococcus multilocularis dual specificity testis specific protein kinase 0.0077 0.01 0.012
Echinococcus granulosus insulin receptor 0.0056 0.006 0.0072
Entamoeba histolytica Rho guanine nucleotide exchange factor, putative 0.0076 0.0098 0.0571
Trichomonas vaginalis ribosomal protein S6 kinase, 90kD, polypeptide, putative 0.0096 0.0139 0.0827
Toxoplasma gondii calcium dependent protein kinase CDPK7 0.0096 0.0139 1
Toxoplasma gondii Oxysterol-binding protein 0.0076 0.0098 0.7102
Schistosoma mansoni dynamin 0.0076 0.0098 0.0098
Entamoeba histolytica protein tyrosine kinase domain-containing protein 0.0056 0.006 0.0327
Entamoeba histolytica cysteine surface protein, putative 0.0056 0.006 0.0327
Brugia malayi Regulator of G protein signaling domain containing protein 0.0824 0.1579 0.1579
Plasmodium vivax serine/threonine protein kinase 6, putative 0.0081 0.0109 0.7725
Onchocerca volvulus Tyrosine kinase receptor Cad96Ca homolog 0.0056 0.006 0.0284
Trichomonas vaginalis conserved hypothetical protein 0.0076 0.0098 0.0571
Leishmania major beta tubulin 0.0038 0.0024 0.1716
Echinococcus granulosus retinal guanylyl cyclase 2 0.0056 0.006 0.0072
Entamoeba histolytica protein kinase, putative 0.0056 0.006 0.0327
Entamoeba histolytica protein tyrosine kinase domain-containing protein 0.0056 0.006 0.0327
Echinococcus granulosus tubulin alpha chain 0.003 0.0009 0.0011
Brugia malayi Protein kinase domain containing protein 0.0056 0.006 0.006
Trichomonas vaginalis AGC family protein kinase 0.0096 0.0139 0.0827
Trichomonas vaginalis conserved hypothetical protein 0.0056 0.006 0.0327
Trichomonas vaginalis tubulin alpha chain, putative 0.0038 0.0024 0.0095
Loa Loa (eye worm) hypothetical protein 0.0076 0.0098 0.0098
Brugia malayi PH domain containing protein 0.0076 0.0098 0.0098
Trichomonas vaginalis AGC family protein kinase 0.0096 0.0139 0.0827
Leishmania major protein kinase, putative 0.0096 0.0139 1
Schistosoma mansoni phosphoinositol 4-phosphate adaptor protein 0.0076 0.0098 0.0098
Brugia malayi tubulin alpha chain - mouse 0.003 0.0009 0.0009
Trichomonas vaginalis hypothetical protein 0.0076 0.0098 0.0571
Echinococcus granulosus tyrosine protein kinase csk 0.0056 0.006 0.0072
Entamoeba histolytica protein kinase domain containing protein 0.0056 0.006 0.0327
Leishmania major alpha tubulin 0.003 0.0009 0.0639
Echinococcus granulosus retinal guanylyl cyclase 2 0.0056 0.006 0.0072
Onchocerca volvulus 0.0076 0.0098 0.0506
Echinococcus multilocularis calcium dependent secretion activator 1 0.0076 0.0098 0.0118
Echinococcus multilocularis Pleckstrin y 0.0076 0.0098 0.0118
Plasmodium falciparum protein kinase, putative 0.0077 0.01 0.7236
Schistosoma mansoni protein kinase 0.0056 0.006 0.006
Leishmania major protein kinase, putative 0.0077 0.01 0.7236
Trichomonas vaginalis TKL family protein kinase 0.0056 0.006 0.0327
Echinococcus multilocularis Rho GTPase activating protein 24 0.0076 0.0098 0.0118
Schistosoma mansoni tyrosine kinase 0.0056 0.006 0.006
Schistosoma mansoni protein kinase 0.0056 0.006 0.006
Loa Loa (eye worm) hypothetical protein 0.0101 0.0149 0.0149
Onchocerca volvulus 0.0076 0.0098 0.0506
Loa Loa (eye worm) voltage and ligand gated potassium channel 0.0042 0.0031 0.0031
Entamoeba histolytica protein kinase domain containing protein 0.0077 0.01 0.0583
Loa Loa (eye worm) hypothetical protein 0.0076 0.0098 0.0098
Plasmodium vivax oxysterol-binding protein/PH domain containing protein 0.0076 0.0098 0.6904
Schistosoma mansoni zinc finger protein 0.0076 0.0098 0.0098
Trypanosoma cruzi NIMA-related kinase, putative 0.0096 0.0139 1
Brugia malayi hypothetical protein 0.0824 0.1579 0.1579
Brugia malayi Probable exocyst complex component Sec5 0.0168 0.028 0.028
Trichomonas vaginalis protein transport protein sec7, putative 0.0076 0.0098 0.0571
Toxoplasma gondii Tyrosine kinase-like (TKL) protein 0.0056 0.006 0.4338
Onchocerca volvulus 0.0056 0.006 0.0284
Trichomonas vaginalis TKL family protein kinase 0.0056 0.006 0.0327
Echinococcus granulosus peroxisome assembly protein 26 0.003 0.0009 0.0011
Entamoeba histolytica protein kinase, putative 0.0056 0.006 0.0327
Schistosoma mansoni tubulin subunit alpha 0.003 0.0009 0.0009
Trichomonas vaginalis TKL family protein kinase 0.0056 0.006 0.0327
Brugia malayi Protein kinase domain containing protein 0.0056 0.006 0.006
Trypanosoma cruzi hypothetical protein 0.0076 0.0098 0.6904
Trypanosoma brucei beta tubulin 0.0038 0.0024 0.1151
Brugia malayi alpha-tubulin 0.003 0.0009 0.0009
Trichomonas vaginalis conserved hypothetical protein 0.0168 0.028 0.173
Echinococcus granulosus alpha tubulin 0.003 0.0009 0.0011
Echinococcus multilocularis basic fibroblast growth factor receptor 1 A 0.0056 0.006 0.0072
Schistosoma mansoni alpha tubulin 0.003 0.0009 0.0009
Echinococcus multilocularis protein tyrosine kinase 0.0056 0.006 0.0072
Loa Loa (eye worm) hypothetical protein 0.0076 0.0098 0.0098
Trichomonas vaginalis AGC family protein kinase 0.0096 0.0139 0.0827
Trichomonas vaginalis TKL family protein kinase 0.0056 0.006 0.0327
Echinococcus granulosus Tubulin beta 2C chain 0.0038 0.0024 0.0028
Echinococcus multilocularis tyrosine protein kinase Fps85D 0.0056 0.006 0.0072
Trichomonas vaginalis TKL family protein kinase 0.0056 0.006 0.0327
Schistosoma mansoni tyrosine kinase 0.0056 0.006 0.006
Plasmodium vivax conserved Plasmodium protein, unknown function 0.0076 0.0098 0.6904
Entamoeba histolytica tyrosin kinase, putative 0.0056 0.006 0.0327
Entamoeba histolytica hypothetical protein, conserved domain containing 0.0076 0.0098 0.0571
Brugia malayi Protein kinase domain containing protein 0.0056 0.006 0.006
Brugia malayi probable spectrin beta chain 0.0076 0.0098 0.0098
Brugia malayi Protein kinase domain containing protein 0.0056 0.006 0.006
Trichomonas vaginalis conserved hypothetical protein 0.0076 0.0098 0.0571
Echinococcus multilocularis tyrosine protein kinase Fyn 0.0056 0.006 0.0072
Onchocerca volvulus 0.0056 0.006 0.0284
Onchocerca volvulus 0.0056 0.006 0.0284
Loa Loa (eye worm) protein kinase domain-containing protein 0.0056 0.006 0.006
Trypanosoma brucei rac serine-threonine kinase, putative 0.0096 0.0139 1
Echinococcus multilocularis pleckstrin y domain containing family A 0.0076 0.0098 0.0118
Schistosoma mansoni protein kinase 0.0056 0.006 0.006
Schistosoma mansoni hypothetical protein 0.0076 0.0098 0.0098
Echinococcus multilocularis arf GAP with SH3 domain, ANK repeat and PH 0.0076 0.0098 0.0118
Trypanosoma cruzi serine/threonine protein kinase, putative 0.0096 0.0139 1
Onchocerca volvulus Putative zinc finger protein 0.0076 0.0098 0.0506
Trichomonas vaginalis conserved hypothetical protein 0.0076 0.0098 0.0571
Schistosoma mansoni vav2 0.0076 0.0098 0.0098
Toxoplasma gondii aurora kinase 0.0081 0.0109 0.787
Trichomonas vaginalis TKL family protein kinase 0.0056 0.006 0.0327
Echinococcus multilocularis tubulin, beta 4A class IVa 0.0038 0.0024 0.0028
Loa Loa (eye worm) G protein-coupled receptor kinase 1 0.4259 0.837 0.837
Loa Loa (eye worm) hypothetical protein 0.0076 0.0098 0.0098
Echinococcus multilocularis DCC interacting protein 13 beta 0.0076 0.0098 0.0118
Trichomonas vaginalis TKL family protein kinase 0.0056 0.006 0.0327
Entamoeba histolytica protein kinase domain containing protein 0.0056 0.006 0.0327
Echinococcus multilocularis ras specific guanine nucleotide releasing factor 0.0076 0.0098 0.0118
Entamoeba histolytica serine/threonine kinase, putative 0.0056 0.006 0.0327
Echinococcus granulosus tyrosine protein kinase csk 0.0056 0.006 0.0072
Loa Loa (eye worm) BEN-1 protein 0.0038 0.0024 0.0024
Trichomonas vaginalis protein kinase atn1, putative 0.0056 0.006 0.0327
Entamoeba histolytica protein tyrosine kinase domain-containing protein 0.0056 0.006 0.0327
Echinococcus multilocularis type II inositol 3,4 bisphosphate 4 phosphatase 0.0076 0.0098 0.0118
Loa Loa (eye worm) TK/KIN16 protein kinase 0.0152 0.025 0.025
Echinococcus multilocularis tyrosine protein kinase transmembrane receptor 0.0056 0.006 0.0072
Entamoeba histolytica protein tyrosine kinase domain-containing protein 0.0056 0.006 0.0327
Trypanosoma brucei protein kinase, putative 0.0096 0.0139 1
Echinococcus multilocularis mitogen activated protein kinase kinase kinase 0.0056 0.006 0.0072
Echinococcus multilocularis fibroblast growth factor receptor 4 0.0056 0.006 0.0072
Trichomonas vaginalis AGC family protein kinase 0.0096 0.0139 0.0827
Onchocerca volvulus 0.0076 0.0098 0.0506
Trichomonas vaginalis conserved hypothetical protein 0.0168 0.028 0.173
Loa Loa (eye worm) TK/FER protein kinase 0.0056 0.006 0.006
Schistosoma mansoni serine/threonine protein kinase 0.0056 0.006 0.006
Trypanosoma cruzi ADP-ribosylation factor family, putative 0.0076 0.0098 0.6904
Echinococcus multilocularis tyrosine protein kinase transmembrane receptor 0.0056 0.006 0.0072
Echinococcus granulosus tyrosine kinase 0.0056 0.006 0.0072
Echinococcus granulosus tyrosine protein kinase Fps85D 0.0056 0.006 0.0072
Onchocerca volvulus Tyrosine kinase homolog 0.0056 0.006 0.0284
Schistosoma mansoni hypothetical protein 0.0519 0.0976 0.0976
Trypanosoma cruzi NIMA-related kinase, putative 0.0096 0.0139 1
Echinococcus multilocularis tyrosine protein kinase shark 0.0056 0.006 0.0072
Loa Loa (eye worm) TK/ALK protein kinase 0.0319 0.0581 0.0581
Echinococcus granulosus serine:threonine protein kinase 12 B 0.0081 0.0109 0.013
Schistosoma mansoni tyrosine-protein kinase fps85d 0.0056 0.006 0.006
Brugia malayi PH domain containing protein 0.0076 0.0098 0.0098
Giardia lamblia Aurora kinase 0.0081 0.0109 1
Entamoeba histolytica protein kinase domain containing protein 0.0056 0.006 0.0327
Echinococcus multilocularis regulator of G protein signaling 3 0.0824 0.1579 0.1886
Toxoplasma gondii AtPH1 family protein 0.0076 0.0098 0.7102
Trichomonas vaginalis TKL family protein kinase 0.0056 0.006 0.0327
Echinococcus multilocularis A kinase anchor protein 10, mitochondrial 0.0824 0.1579 0.1886
Brugia malayi A-kinase anchor protein 10, precursor 0.0824 0.1579 0.1579
Trichomonas vaginalis TKL family protein kinase 0.0056 0.006 0.0327
Entamoeba histolytica hypothetical protein 0.0056 0.006 0.0327
Trichomonas vaginalis voltage and ligand gated potassium channel, putative 0.0039 0.0026 0.0108
Leishmania major alpha tubulin 0.003 0.0009 0.0639
Schistosoma mansoni oxysterol-binding protein 1 0.0076 0.0098 0.0098
Leishmania major alpha tubulin 0.003 0.0009 0.0639
Entamoeba histolytica protein kinase, putative 0.0096 0.0139 0.0827
Plasmodium falciparum acylated pleckstrin-homology domain-containing protein, putative 0.0076 0.0098 0.7102
Loa Loa (eye worm) TK/FER protein kinase 0.0056 0.006 0.006
Entamoeba histolytica hypothetical protein 0.0168 0.028 0.173
Leishmania major protein kinase, putative 0.0081 0.0109 0.787
Trichomonas vaginalis centaurin/arf, putative 0.0076 0.0098 0.0571
Echinococcus granulosus ephrin type A receptor 4 A 0.0056 0.006 0.0072
Onchocerca volvulus 0.0056 0.006 0.0284
Entamoeba histolytica protein tyrosine kinase domain-containing protein 0.0056 0.006 0.0327
Schistosoma mansoni tyrosine kinase 0.0056 0.006 0.006
Trypanosoma brucei beta tubulin 0.0038 0.0024 0.1151
Schistosoma mansoni tyrosine kinase 0.0056 0.006 0.006
Echinococcus granulosus arf GAP with coiled coil ANK repeat and PH 0.0076 0.0098 0.0118
Echinococcus granulosus 3'partial|tyrosine protein kinase Fgr 0.0056 0.006 0.0072
Trichomonas vaginalis TKL family protein kinase 0.0056 0.006 0.0327
Brugia malayi Guanylyl cyclase protein 23 0.0056 0.006 0.006
Loa Loa (eye worm) TKL/RAF/KSR protein kinase 0.0056 0.006 0.006
Schistosoma mansoni serine/threonine-protein kinase 0.0096 0.0139 0.0139
Plasmodium vivax calcium-dependent protein kinase 7, putative 0.0096 0.0139 1
Entamoeba histolytica Rho guanine nucleotide exchange factor, putative 0.0076 0.0098 0.0571
Schistosoma mansoni hypothetical protein 0.0076 0.0098 0.0098
Schistosoma mansoni plexin 0.0902 0.1733 0.1733
Plasmodium falciparum protein kinase, putative 0.0056 0.006 0.4338
Entamoeba histolytica protein kinase, putative 0.0056 0.006 0.0327
Loa Loa (eye worm) hypothetical protein 0.0076 0.0098 0.0098
Onchocerca volvulus 0.0056 0.006 0.0284
Loa Loa (eye worm) PH domain-containing protein 0.0076 0.0098 0.0098
Trichomonas vaginalis TKL family protein kinase 0.0056 0.006 0.0327
Trichomonas vaginalis TKL family protein kinase 0.0056 0.006 0.0327
Entamoeba histolytica hypothetical protein 0.0056 0.006 0.0327
Entamoeba histolytica Rho guanine nucleotide exchange factor, putative 0.0076 0.0098 0.0571
Entamoeba histolytica tyrosine kinase, putative 0.0056 0.006 0.0327
Onchocerca volvulus 0.0056 0.006 0.0284
Loa Loa (eye worm) TK/FER protein kinase 0.0056 0.006 0.006
Loa Loa (eye worm) hypothetical protein 0.0096 0.0139 0.0139
Echinococcus granulosus tubulin beta 4A class IVa 0.0038 0.0024 0.0028
Trichomonas vaginalis conserved hypothetical protein 0.0076 0.0098 0.0571
Echinococcus granulosus neurotracting:lsamp:neurotrimin:obcam 0.0096 0.0139 0.0166
Loa Loa (eye worm) hypothetical protein 0.0902 0.1733 0.1733
Echinococcus granulosus beta tubulin 0.0038 0.0024 0.0028
Echinococcus granulosus melanoma receptor tyrosine protein kinase 0.0056 0.006 0.0072
Toxoplasma gondii protein kinase 0.0056 0.006 0.4338
Brugia malayi Tubulin alpha-2 chain 0.003 0.0009 0.0009
Echinococcus multilocularis tyrosine protein kinase lyn tyrosine protein kinase blk 0.0056 0.006 0.0072
Brugia malayi Oxysterol-binding protein 0.0076 0.0098 0.0098
Echinococcus multilocularis FERM and pleckstrin domain containing protein 0.0076 0.0098 0.0118
Plasmodium falciparum alpha tubulin 2 0.003 0.0009 0.0639
Brugia malayi ephrin receptor 1 precursor 0.0056 0.006 0.006
Trichomonas vaginalis TKL family protein kinase 0.0056 0.006 0.0327
Trypanosoma brucei protein kinase, putative 0.0077 0.01 0.7047
Trichomonas vaginalis TKL family protein kinase 0.0056 0.006 0.0327
Trichomonas vaginalis TKL family protein kinase 0.0056 0.006 0.0327
Brugia malayi Voltage-gated potassium channel, HERG (KCNH2)-related. C. elegans unc-103 ortholog 0.0042 0.0031 0.0031
Entamoeba histolytica protein kinase domain containing protein 0.0056 0.006 0.0327
Entamoeba histolytica PH domain containing protein kinase, putative 0.0096 0.0139 0.0827
Schistosoma mansoni protein kinase 0.0056 0.006 0.006
Entamoeba histolytica serine/threonine- protein kinase 6, putative 0.0081 0.0109 0.0639
Plasmodium falciparum protein kinase, putative 0.0056 0.006 0.4338
Schistosoma mansoni tyrosine protein kinase fes (fps) (ptk group IV) 0.0056 0.006 0.006
Entamoeba histolytica serine/threonine kinase, putative 0.0056 0.006 0.0327
Echinococcus multilocularis tyrosine protein kinase csk 0.0056 0.006 0.0072
Loa Loa (eye worm) TK/FER protein kinase 0.0056 0.006 0.006
Trypanosoma cruzi beta tubulin, putative 0.0038 0.0024 0.1151
Plasmodium falciparum phosphatidylinositol transfer protein, putative 0.0076 0.0098 0.7102
Echinococcus granulosus collagen type iv alpha 3 binding protein 0.0076 0.0098 0.0118
Echinococcus granulosus Immunoglobulin 0.0096 0.0139 0.0166
Schistosoma mansoni ephrin receptor 0.0061 0.007 0.007
Trichomonas vaginalis conserved hypothetical protein 0.0168 0.028 0.173
Loa Loa (eye worm) TK/EGFR protein kinase 0.0056 0.006 0.006
Loa Loa (eye worm) TKL/RAF/RAF protein kinase 0.0056 0.006 0.006
Giardia lamblia Beta tubulin 0.0038 0.0024 0.149
Brugia malayi bone morphogenetic protein type 1 receptor 0.0056 0.006 0.006
Brugia malayi Protein kinase domain containing protein 0.0056 0.006 0.006
Trichomonas vaginalis 3-phosphoinositide dependent protein kinase-1, putative 0.0096 0.0139 0.0827
Trichomonas vaginalis br serine/threonine-protein kinase, putative 0.0056 0.006 0.0327
Schistosoma mansoni tyrosine kinase 0.0056 0.006 0.006
Echinococcus multilocularis GRB2 associated binding protein 3 0.0076 0.0098 0.0118
Brugia malayi Protein kinase domain containing protein 0.032 0.0581 0.0581
Echinococcus multilocularis insulin receptor 0.0056 0.006 0.0072
Entamoeba histolytica p21-activated kinase 0.0096 0.0139 0.0827
Brugia malayi Probable tyrosine-protein kinase kin-31 0.0056 0.006 0.006
Schistosoma mansoni tyrosine kinase 0.0056 0.006 0.006
Echinococcus granulosus atrial natriuretic peptide receptor 1 0.0056 0.006 0.0072
Loa Loa (eye worm) variant SH3 domain-containing protein 0.0076 0.0098 0.0098
Loa Loa (eye worm) hypothetical protein 0.0101 0.0149 0.0149
Leishmania major beta tubulin 0.0038 0.0024 0.1716
Entamoeba histolytica protein kinase, putative 0.0056 0.006 0.0327
Echinococcus multilocularis Pleckstrin domain containing protein, family B 0.0076 0.0098 0.0118
Leishmania major alpha tubulin 0.003 0.0009 0.0639
Brugia malayi PH domain containing protein 0.0076 0.0098 0.0098
Entamoeba histolytica tyrosine kinase, putative 0.0056 0.006 0.0327
Trichomonas vaginalis TKL family protein kinase 0.0056 0.006 0.0327
Echinococcus granulosus proto oncogene tyrosine protein kinase LCK 0.0056 0.006 0.0072
Loa Loa (eye worm) hypothetical protein 0.0032 0.0011 0.0011
Entamoeba histolytica protein kinase, putative 0.0096 0.0139 0.0827
Loa Loa (eye worm) hypothetical protein 0.0383 0.0706 0.0706
Leishmania major alpha tubulin 0.003 0.0009 0.0639
Brugia malayi TBC domain containing protein 0.0076 0.0098 0.0098
Echinococcus multilocularis hypothetical protein 0.003 0.0009 0.0011
Trichomonas vaginalis centaurin alpha, putative 0.0076 0.0098 0.0571
Loa Loa (eye worm) hypothetical protein 0.0383 0.0706 0.0706
Echinococcus multilocularis heat shock protein 70 0.0056 0.006 0.0072
Brugia malayi Protein kinase domain containing protein 0.0056 0.006 0.006
Echinococcus multilocularis arf GAP with coiled coil, ANK repeat and PH 0.0076 0.0098 0.0118
Trypanosoma cruzi protein kinase, putative 0.0056 0.006 0.3952
Loa Loa (eye worm) rho-GTPase-activating 0.0076 0.0098 0.0098
Schistosoma mansoni hypothetical protein 0.0383 0.0706 0.0706
Trichomonas vaginalis TKL family protein kinase 0.0056 0.006 0.0327
Loa Loa (eye worm) RGC/RGC protein kinase 0.0056 0.006 0.006
Schistosoma mansoni regulator of G protein signaling 0.0824 0.1579 0.1579
Entamoeba histolytica protein kinase, putative 0.0081 0.0109 0.0639
Leishmania major beta tubulin 0.0038 0.0024 0.1716
Loa Loa (eye worm) AUR protein kinase 0.0081 0.0109 0.0109
Entamoeba histolytica tyrosine kinase, putative 0.0056 0.006 0.0327
Schistosoma mansoni protein tyrosine kinase 0.0056 0.006 0.006
Echinococcus granulosus exocyst complex component 2 0.0168 0.028 0.0335
Echinococcus granulosus tyrosine protein kinase Fyn 0.0056 0.006 0.0072
Trichomonas vaginalis conserved hypothetical protein 0.0824 0.1579 1
Leishmania major beta tubulin 0.0038 0.0024 0.1716
Schistosoma mansoni tyrosine kinase 0.0056 0.006 0.006
Echinococcus multilocularis transcription factor collier 0.0168 0.028 0.0335
Trichomonas vaginalis TKL family protein kinase 0.0056 0.006 0.0327
Echinococcus multilocularis tubulin alpha chain 0.003 0.0009 0.0011
Echinococcus multilocularis retinal guanylyl cyclase 2 0.0056 0.006 0.0072
Echinococcus granulosus c src tyrosine kinase 0.0056 0.006 0.0072
Echinococcus granulosus tyrosine protein kinase Fes:Fps 0.0056 0.006 0.0072
Echinococcus multilocularis tyrosine protein kinase Fyn 0.0056 0.006 0.0072
Trichomonas vaginalis conserved hypothetical protein 0.0168 0.028 0.173
Onchocerca volvulus Protein melted homolog 0.0076 0.0098 0.0506
Plasmodium falciparum conserved Plasmodium protein, unknown function 0.0076 0.0098 0.7102
Echinococcus granulosus kinase suppressor of Ras 1 0.0056 0.006 0.0072
Echinococcus granulosus protein tyrosine kinase 0.0056 0.006 0.0072
Echinococcus multilocularis tyrosine protein kinase 0.0056 0.006 0.0072
Loa Loa (eye worm) hypothetical protein 0.0824 0.1579 0.1579
Echinococcus multilocularis tubulin alpha 1C chain 0.003 0.0009 0.0011
Entamoeba histolytica hypothetical protein 0.0096 0.0139 0.0827
Echinococcus granulosus serine/threonine protein kinase 0.0096 0.0139 0.0166
Trichomonas vaginalis ankyrin repeat-containing protein, putative 0.0056 0.006 0.0327
Echinococcus granulosus protein kinase 0.0056 0.006 0.0072
Echinococcus multilocularis retinal guanylyl cyclase 2 0.0056 0.006 0.0072
Echinococcus granulosus fibroblast growth factor receptor 4 0.0056 0.006 0.0072
Schistosoma mansoni tyrosine-protein kinase fps85d 0.0056 0.006 0.006
Echinococcus multilocularis tubulin alpha 3 chain 0.003 0.0009 0.0011
Loa Loa (eye worm) RGC/RGC protein kinase 0.0056 0.006 0.006
Brugia malayi PH domain containing protein 0.0076 0.0098 0.0098
Echinococcus granulosus tyrosine protein kinase transmembrane receptor 0.0056 0.006 0.0072
Entamoeba histolytica hypothetical protein, conserved domain containing 0.0076 0.0098 0.0571
Echinococcus granulosus semaphorin 5B 0.0383 0.0706 0.0843
Onchocerca volvulus Putative neuronal RhoA GEF protein 0.0076 0.0098 0.0506
Plasmodium vivax tyrosine kinase-like protein, putative 0.0056 0.006 0.3952
Trypanosoma cruzi STE/STE11 serine/threonine-protein kinase, putative 0.0077 0.01 0.7047
Trypanosoma cruzi Serine/threonine-protein kinase NEK21, putative 0.0096 0.0139 1
Loa Loa (eye worm) RGC/RGC protein kinase 0.0056 0.006 0.006
Loa Loa (eye worm) hypothetical protein 0.0101 0.0149 0.0149
Loa Loa (eye worm) TK/RYK protein kinase 0.0056 0.006 0.006
Echinococcus granulosus regulator of G protein signaling 7 0.0824 0.1579 0.1886
Trichomonas vaginalis conserved hypothetical protein 0.0076 0.0098 0.0571
Trichomonas vaginalis protein tyrosine kinase, putative 0.0056 0.006 0.0327
Echinococcus granulosus tyrosine protein kinase Blk 0.0056 0.006 0.0072
Loa Loa (eye worm) TK/Met protein kinase 0.0056 0.006 0.006
Echinococcus granulosus aurora kinase A 0.0081 0.0109 0.013
Echinococcus multilocularis Tubulin beta 2C chain 0.0038 0.0024 0.0028
Entamoeba histolytica serine/threonine- protein kinase 6 , putative 0.0081 0.0109 0.0639
Trichomonas vaginalis AGC family protein kinase 0.0096 0.0139 0.0827
Schistosoma mansoni tyrosine kinase 0.0056 0.006 0.006
Entamoeba histolytica tyrosine kinase, putative 0.0056 0.006 0.0327
Brugia malayi Protein kinase domain containing protein 0.0056 0.006 0.006
Trichomonas vaginalis TKL family protein kinase 0.0056 0.006 0.0327
Echinococcus multilocularis Regulator of G protein signaling 20 0.0824 0.1579 0.1886
Schistosoma mansoni serine/threonine protein kinase 0.0056 0.006 0.006
Echinococcus multilocularis FL cytokine receptor 0.0056 0.006 0.0072
Entamoeba histolytica tyrosine kinase, putative 0.0056 0.006 0.0327
Loa Loa (eye worm) hypothetical protein 0.0056 0.006 0.006
Plasmodium falciparum serine/threonine protein kinase, putative 0.0081 0.0109 0.787
Loa Loa (eye worm) beta-tubulin 0.0038 0.0024 0.0024
Echinococcus multilocularis protein kinase 0.0056 0.006 0.0072
Trichomonas vaginalis conserved hypothetical protein 0.0056 0.006 0.0327
Brugia malayi Protein kinase domain containing protein 0.0056 0.006 0.006
Loa Loa (eye worm) TK/FER protein kinase 0.0056 0.006 0.006
Brugia malayi Plexin repeat family protein 0.0902 0.1733 0.1733
Echinococcus multilocularis retinal guanylyl cyclase 2 0.0056 0.006 0.0072
Loa Loa (eye worm) tubulin beta chain 0.0038 0.0024 0.0024
Trichomonas vaginalis TKL family protein kinase 0.0056 0.006 0.0327
Echinococcus multilocularis basement membrane specific heparan sulfate 0.0096 0.0139 0.0166
Trichomonas vaginalis tubulin epsilon chain, putative 0.0038 0.0024 0.0095
Leishmania major alpha tubulin 0.003 0.0009 0.0639
Brugia malayi SH2 domain containing protein 0.0056 0.006 0.006
Trichomonas vaginalis TKL family protein kinase 0.0056 0.006 0.0327
Entamoeba histolytica protein kinase, putative 0.0096 0.0139 0.0827
Entamoeba histolytica protein kinase domain containing protein 0.0224 0.0392 0.2438
Loa Loa (eye worm) TKL/MLK/HH498 protein kinase 0.0056 0.006 0.006
Entamoeba histolytica PH domain containing protein kinase, putative 0.0096 0.0139 0.0827
Toxoplasma gondii protein kinase domain-containing protein 0.0056 0.006 0.4338
Trichomonas vaginalis TKL family protein kinase 0.0056 0.006 0.0327
Trypanosoma cruzi hypothetical protein 0.0076 0.0098 0.6904
Echinococcus multilocularis potassium voltage gated channel subfamily H 0.0042 0.0031 0.0037
Brugia malayi serine/threonine-protein kinase 6 0.0081 0.0109 0.0109
Brugia malayi Variant SH3 domain containing protein 0.0076 0.0098 0.0098
Brugia malayi Protein kinase domain containing protein 0.0056 0.006 0.006
Echinococcus granulosus epidermal growth factor receptor 0.0056 0.006 0.0072
Trypanosoma cruzi hypothetical protein 0.0076 0.0098 0.6904
Leishmania major protein kinase, putative 0.0056 0.006 0.4338
Entamoeba histolytica tyrosine kinase, putative 0.0056 0.006 0.0327
Echinococcus multilocularis mitogen activated protein kinase kinase kinase 0.0056 0.006 0.0072
Schistosoma mansoni regulator of G protein signaling 3 rgs3 0.0824 0.1579 0.1579
Entamoeba histolytica tyrosin kinase, putative 0.0056 0.006 0.0327
Echinococcus multilocularis tyrosine protein kinase Btk29A 0.0056 0.006 0.0072
Echinococcus granulosus tyrosine kinase 0.0056 0.006 0.0072
Brugia malayi PH domain containing protein 0.0076 0.0098 0.0098
Loa Loa (eye worm) hypothetical protein 0.0168 0.028 0.028
Trichomonas vaginalis guanyl-nucleotide exchange factor, putative 0.0076 0.0098 0.0571
Echinococcus granulosus oxysterol binding protein 9 0.0076 0.0098 0.0118
Echinococcus multilocularis Oxysterol binding protein 11 0.0076 0.0098 0.0118
Entamoeba histolytica Rho guanine nucleotide exchange factor, putative 0.0076 0.0098 0.0571
Echinococcus granulosus tubulin alpha chain 0.003 0.0009 0.0011
Echinococcus granulosus natriuretic peptide receptor 1 0.0056 0.006 0.0072
Plasmodium falciparum oxysterol-binding protein, putative 0.0076 0.0098 0.7102
Entamoeba histolytica serine/threonine kinase, putative 0.0056 0.006 0.0327
Schistosoma mansoni voltage-gated potassium channel 0.0045 0.0039 0.0039
Echinococcus granulosus Tubulin alpha 1 chain 0.003 0.0009 0.0011
Entamoeba histolytica protein tyrosine kinase domain-containing protein 0.0056 0.006 0.0327
Loa Loa (eye worm) tubulin alpha chain 0.003 0.0009 0.0009
Entamoeba histolytica tyrosine kinase, putative 0.0056 0.006 0.0327
Loa Loa (eye worm) AUR protein kinase 0.0081 0.0109 0.0109
Loa Loa (eye worm) TK/FAK protein kinase 0.0056 0.006 0.006
Loa Loa (eye worm) alpha-tubulin 0.003 0.0009 0.0009
Trichomonas vaginalis centaurin gamma, putative 0.0076 0.0098 0.0571
Trichomonas vaginalis TK family protein kinase 0.0056 0.006 0.0327
Schistosoma mansoni goodpasture antigen-binding protein 0.0076 0.0098 0.0098
Schistosoma mansoni alpha tubulin 0.003 0.0009 0.0009
Echinococcus granulosus dynamin 1 0.0076 0.0098 0.0118
Echinococcus granulosus pleckstrin y domain containing family A 0.0076 0.0098 0.0118
Schistosoma mansoni tyrosine kinase 0.0056 0.006 0.006
Echinococcus granulosus Pleckstrin domain containing protein family B 0.0076 0.0098 0.0118
Loa Loa (eye worm) sema domain-containing protein 0.0383 0.0706 0.0706
Brugia malayi beta-tubulin, identical 0.0038 0.0024 0.0024
Trichomonas vaginalis TKL family protein kinase 0.0056 0.006 0.0327
Echinococcus granulosus tyrosine protein kinase ABL1 0.0056 0.006 0.0072
Brugia malayi Plekhf2 protein 0.0076 0.0098 0.0098
Entamoeba histolytica tyrosine kinase, putative 0.0056 0.006 0.0327
Trichomonas vaginalis Clan MA, family M8, leishmanolysin-like metallopeptidase 0.0168 0.028 0.173
Trypanosoma brucei beta tubulin 0.0038 0.0024 0.1151
Trichomonas vaginalis TKL family protein kinase 0.0056 0.006 0.0327
Trichomonas vaginalis AGC family protein kinase 0.0056 0.006 0.0327
Echinococcus granulosus tyrosine protein kinase transmembrane receptor 0.0056 0.006 0.0072
Loa Loa (eye worm) TK protein kinase 0.0056 0.006 0.006
Entamoeba histolytica protein kinase, putative 0.0056 0.006 0.0327
Trichomonas vaginalis conserved hypothetical protein 0.0076 0.0098 0.0571
Plasmodium falciparum calcium-dependent protein kinase 7 0.0096 0.0139 1
Schistosoma mansoni alpha tubulin 0.003 0.0009 0.0009
Schistosoma mansoni tyrosine kinase 0.0056 0.006 0.006
Leishmania major folate/biopterin transporter, putative 0.0096 0.0139 1
Echinococcus granulosus tyrosine kinase 0.0056 0.006 0.0072
Entamoeba histolytica hypothetical protein 0.0056 0.006 0.0327
Leishmania major serine/threonine-protein kinase a, putative 0.0096 0.0139 1
Loa Loa (eye worm) cytohesin 3 0.0076 0.0098 0.0098
Brugia malayi regulator of G-protein signaling rgs-7 0.0824 0.1579 0.1579
Trichomonas vaginalis TKL family protein kinase 0.0056 0.006 0.0327
Echinococcus granulosus Pleckstrin y 0.0076 0.0098 0.0118
Entamoeba histolytica hypothetical protein 0.0168 0.028 0.173
Brugia malayi SH2 domain containing protein 0.0056 0.006 0.006
Brugia malayi Cytohesin 3 0.0076 0.0098 0.0098
Brugia malayi Tyrosine-protein kinase PR2 0.0056 0.006 0.006
Leishmania major alpha tubulin 0.003 0.0009 0.0639
Entamoeba histolytica PH domain containing protein kinase, putative 0.0096 0.0139 0.0827
Leishmania major beta tubulin 0.0038 0.0024 0.1716
Loa Loa (eye worm) AGC/AKT protein kinase 0.0096 0.0139 0.0139
Entamoeba histolytica protein kinase, putative 0.0096 0.0139 0.0827
Loa Loa (eye worm) TK/INSR protein kinase 0.0056 0.006 0.006
Loa Loa (eye worm) TK/KIN6 protein kinase 0.0056 0.006 0.006
Leishmania major beta tubulin 0.0038 0.0024 0.1716
Loa Loa (eye worm) TK/ACK protein kinase 0.0056 0.006 0.006
Echinococcus multilocularis Ras associated and pleckstrin y 0.0076 0.0098 0.0118
Entamoeba histolytica protein tyrosine kinase domain-containing protein 0.0056 0.006 0.0327
Plasmodium falciparum tubulin beta chain 0.0038 0.0024 0.1716
Echinococcus multilocularis activin receptor type 0.0077 0.01 0.012
Schistosoma mansoni tubulin subunit beta 0.0038 0.0024 0.0024
Brugia malayi Protein kinase domain containing protein 0.0056 0.006 0.006
Loa Loa (eye worm) TK/FER protein kinase 0.0056 0.006 0.006
Entamoeba histolytica PH domain containing protein 0.0076 0.0098 0.0571
Echinococcus granulosus Rho GTPase activating protein 24 0.0076 0.0098 0.0118
Trichomonas vaginalis ankyrin repeat-containing protein, putative 0.0076 0.0098 0.0571
Echinococcus multilocularis Immunoglobulin 0.0096 0.0139 0.0166
Brugia malayi PH domain containing protein 0.0076 0.0098 0.0098
Echinococcus granulosus defective proboscis extension response 0.0096 0.0139 0.0166
Loa Loa (eye worm) TK protein kinase 0.0056 0.006 0.006
Trichomonas vaginalis development and differentiation-enhancing factor, ddef, putative 0.0076 0.0098 0.0571
Leishmania major protein kinase, putative 0.0096 0.0139 1
Entamoeba histolytica hypothetical protein 0.0824 0.1579 1
Echinococcus granulosus DCC interacting protein 13 beta 0.0076 0.0098 0.0118
Schistosoma mansoni tyrosine kinase 0.0056 0.006 0.006
Trichomonas vaginalis AGC family protein kinase 0.0081 0.0109 0.0639
Echinococcus granulosus epidermal growth factor receptor 0.0056 0.006 0.0072
Echinococcus multilocularis tubulin subunit beta 0.0038 0.0024 0.0028
Schistosoma mansoni tyrosine kinase 0.0056 0.006 0.006
Schistosoma mansoni axis inhibition protein axin 0.0824 0.1579 0.1579
Trichomonas vaginalis Clan MA, family M8, leishmanolysin-like metallopeptidase 0.0168 0.028 0.173
Giardia lamblia Kinase 0.0056 0.006 0.5116
Trichomonas vaginalis AGC family protein kinase 0.0096 0.0139 0.0827
Echinococcus granulosus dual specificity testis-specific protein kinase 0.0077 0.01 0.012
Plasmodium falciparum PH domain-containing protein, putative 0.0076 0.0098 0.7102
Loa Loa (eye worm) hypothetical protein 0.0076 0.0098 0.0098
Leishmania major beta tubulin 0.0038 0.0024 0.1716
Echinococcus granulosus GRB2 associated binding protein 3 0.0076 0.0098 0.0118
Echinococcus granulosus retinal guanylyl cyclase 2 0.0056 0.006 0.0072
Toxoplasma gondii alpha-tubulin I, putative 0.003 0.0009 0.0639
Entamoeba histolytica hypothetical protein 0.0824 0.1579 1
Leishmania major beta tubulin 0.0038 0.0024 0.1716
Onchocerca volvulus 0.0056 0.006 0.0284
Brugia malayi protein-tyrosine kinase 0.0056 0.006 0.006
Trichomonas vaginalis TKL family protein kinase 0.0056 0.006 0.0327

Activities

Activity type Activity value Assay description Source Reference
AUC (ADMET) = -1365 Area under curve gives the effective duration for the angiotensin II antagonist effect of the compound. ChEMBL. 7636853
Inhibition (functional) = -18 % In vivo concentration of the compound inhibiting angiotensin II (A II) induced pressor response in conscious normotensive rats 30 mins after oral administration of 2 microM/kg. ChEMBL. 7636853
Ki (binding) = 7.7 nM Inhibition of [3H]-angiotensin II binding to rat adrenal cortex membrane containing angiotensin II receptor, type 1 ChEMBL. 7636853
Ki (binding) = 7.7 nM Inhibition of [3H]-angiotensin II binding to rat adrenal cortex membrane containing angiotensin II receptor, type 1 ChEMBL. 7636853

Phenotypes

Whole-cell/tissue/organism interactions

We have no records of whole-cell/tissue assays done with this compound What does this mean?

Many chemical entities in TDR Targets come from high-throughput screenings with whole cells or tissue samples, and not all assayed compounds have been tested against a single a single target protein, probably because they get ruled out during screening process. Even if these compounds may have not been of interest in the original screening, they may come as interesting leads for other screening assays. Furthermore, we may be able to propose drug-target associations using chemical similarities and network patterns.

Annotated phenotypes:

We have no manually annotated phenotypes for this drug. What does this mean? / Care to help?
In TDR Targets, information about phenotypes that are caused by drugs, or by genetic manipulation of cells (e.g. gene knockouts or knockdowns) is manually curated from the literature. These descriptions help to describe the potential of the target for drug development. If no information is available for this gene or if the information is incomplete, this may mean that i) the papers containing this information either appeared after the curation effort for this organism was carried out or they were inadvertently missed by curators; or that ii) the curation effort for this organism has not yet started.
 
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External resources for this compound

Bibliographic References

1 literature reference was collected for this gene.

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