Detailed information for compound 1654134

Basic information

Technical information
  • Name: Unnamed compound
  • MW: 340.327 | Formula: C19H16O6
  • H donors: 2 H acceptors: 4 LogP: 2.63 Rotable bonds: 5
    Rule of 5 violations (Lipinski): 1
  • SMILES: CCOC(=O)Cc1cc(O)cc2c1c(=O)cc(o2)c1ccc(cc1)O
  • InChi: 1S/C19H16O6/c1-2-24-18(23)8-12-7-14(21)9-17-19(12)15(22)10-16(25-17)11-3-5-13(20)6-4-11/h3-7,9-10,20-21H,2,8H2,1H3
  • InChiKey: LMRSBJOFWPRFJK-UHFFFAOYSA-N  


Substructure search Similarity search

Network

Hover on a compound node to display the structore

Synonyms

No synonyms found for this compound

Targets

Known targets for this compound

No curated genes were found associated with this compound

Predicted pathogen targets for this compound

By orthology
No druggable targets predicted by orthology data
By sequence similarity to non orthologous known druggable targets
No druggable targets predicted by sequence similarity
Obtained from network model

Ranking Plot

Putative Targets List

Species Potential target Raw Global Species
Brugia malayi 3-hydroxyacyl-CoA dehydrogenase type II 0.0119 0.1145 0.1982
Brugia malayi threonyl-tRNA synthetase, cytoplasmic 0.0013 0.0016 0.0025
Schistosoma mansoni nAChR subunit 0.0025 0.0145 0.0191
Mycobacterium ulcerans lysyl-tRNA synthetase 0.005 0.0413 0.0716
Echinococcus multilocularis chromodomain helicase DNA binding protein 4 0.0013 0.002 0.0025
Echinococcus multilocularis serine:threonine protein kinase PLK1 0.0098 0.0918 0.122
Loa Loa (eye worm) hypothetical protein 0.0025 0.0145 0.0249
Brugia malayi Hypothetical 52.5 kDa protein ZK945.1 in chromosome II, putative 0.004 0.0301 0.052
Echinococcus multilocularis solute carrier family 22 0.0032 0.0217 0.0287
Toxoplasma gondii thioredoxin reductase 0.0039 0.03 0.0453
Loa Loa (eye worm) hypothetical protein 0.0032 0.0217 0.0373
Leishmania major 3-oxoacyl-(acyl-carrier protein) reductase, putative 0.0119 0.1145 0.3004
Trypanosoma cruzi dihydrolipoamide dehydrogenase, putative 0.0014 0.0027 0.007
Plasmodium vivax GTP-binding nuclear protein RAN/TC4, putative 0.0023 0.0129 0.0128
Onchocerca volvulus 0.0025 0.0145 0.0573
Trypanosoma brucei glucose transporter, putative 0.007 0.0621 0.1628
Loa Loa (eye worm) hypothetical protein 0.004 0.0305 0.0527
Trichomonas vaginalis conserved hypothetical protein 0.0225 0.2265 0.3922
Trypanosoma brucei lysyl-tRNA synthetase, putative 0.005 0.0413 0.1085
Mycobacterium tuberculosis Lysyl-tRNA synthetase 1 LysS (lysine--tRNA ligase 1) (LysRS 1) (lysine translase) 0.0043 0.0333 0.1301
Trichomonas vaginalis glucosylceramidase, putative 0.0284 0.2892 0.5009
Schistosoma mansoni microtubule-associated protein tau 0.072 0.7517 1
Trichomonas vaginalis fructose-bisphosphate aldolase, putative 0.0305 0.3115 0.5395
Mycobacterium tuberculosis Probable nitrite reductase [NAD(P)H] large subunit [FAD flavoprotein] NirB 0.009 0.0836 0.3263
Echinococcus multilocularis nicotinic acetylcholine receptor a11 subunit 0.0025 0.0145 0.0191
Plasmodium falciparum ataxin-2 like protein, putative 0.0056 0.0476 0.0475
Schistosoma mansoni sodium/chloride dependent transporter 0.0017 0.0061 0.0079
Onchocerca volvulus Serine\/threonine kinase homolog 0.0098 0.0918 0.3655
Echinococcus granulosus sodium and chloride dependent glycine 0.0017 0.0061 0.0079
Toxoplasma gondii calcium-dependent protein kinase CDPK2A 0.0069 0.0615 0.0929
Brugia malayi Neurotransmitter-gated ion-channel transmembrane region family protein 0.0025 0.0145 0.0249
Echinococcus multilocularis RUN 0.002 0.0098 0.0129
Trichomonas vaginalis conserved hypothetical protein 0.0032 0.0217 0.0375
Mycobacterium tuberculosis Possible DNA-damage-inducible protein P DinP (DNA polymerase V) (pol IV 2) (DNA nucleotidyltransferase (DNA-directed)) 0.0019 0.0084 0.0328
Loa Loa (eye worm) RNA binding protein 0.0063 0.0546 0.0944
Loa Loa (eye worm) serotonin transporter b 0.0017 0.0061 0.0103
Schistosoma mansoni norepinephrine/norepinephrine transporter 0.0017 0.0061 0.0079
Trichomonas vaginalis D-aminoacylase, putative 0.004 0.0301 0.0522
Onchocerca volvulus 0.0032 0.0217 0.0859
Toxoplasma gondii ABC1 family protein 0.004 0.0301 0.0455
Schistosoma mansoni carbonic anhydrase-related 0.0174 0.1728 0.2297
Trichomonas vaginalis sugar transporter, putative 0.0032 0.0217 0.0375
Loa Loa (eye worm) hypothetical protein 0.0032 0.0217 0.0373
Loa Loa (eye worm) hypothetical protein 0.0013 0.0023 0.0039
Mycobacterium tuberculosis Probable conserved integral membrane transport protein 0.0032 0.0217 0.0845
Schistosoma mansoni glucose transport protein 0.0225 0.2265 0.3012
Trypanosoma cruzi carbonic anhydrase-like protein, putative 0.0371 0.3812 1
Giardia lamblia NADH oxidase lateral transfer candidate 0.0014 0.0027 0.0035
Leishmania major aldehyde dehydrogenase, mitochondrial precursor 0.0126 0.1219 0.3198
Trichomonas vaginalis lysyl-tRNA synthetase, putative 0.0044 0.0348 0.0603
Trypanosoma cruzi cytochrome P450, putative 0.0055 0.0468 0.1228
Trichomonas vaginalis chromodomain helicase DNA binding protein, putative 0.0018 0.0077 0.0133
Schistosoma mansoni hypothetical protein 0.0017 0.0065 0.0085
Schistosoma mansoni histone-lysine n-methyltransferase suv9 0.0043 0.0339 0.0449
Brugia malayi RNA binding protein 0.0063 0.0546 0.0944
Loa Loa (eye worm) follicle stimulating hormone receptor 0.024 0.2423 0.4194
Brugia malayi major facilitator superfamily protein 0.0032 0.0217 0.0373
Loa Loa (eye worm) hypothetical protein 0.0037 0.0279 0.0481
Plasmodium falciparum carbonic anhydrase 0.0174 0.1728 0.1727
Loa Loa (eye worm) ACC-1 protein 0.0025 0.0145 0.0249
Onchocerca volvulus 0.0032 0.0217 0.0859
Trypanosoma cruzi trypanothione reductase, putative 0.0014 0.0027 0.007
Trichomonas vaginalis sugar transporter, putative 0.0032 0.0217 0.0375
Brugia malayi glutaminase DH11.1 0.0556 0.5774 1
Trichomonas vaginalis sugar transport protein, putative 0.0032 0.0217 0.0375
Schistosoma mansoni nAChR subunit 0.0025 0.0145 0.0191
Trypanosoma brucei DNA polymerase IV, putative 0.0019 0.0084 0.022
Trichomonas vaginalis conserved hypothetical protein 0.0011 0.0001 0.0002
Loa Loa (eye worm) hypothetical protein 0.0013 0.0023 0.0038
Schistosoma mansoni nuclear transcription factor X-box binding 1 (nfx1) 0.0032 0.0217 0.0287
Trypanosoma brucei sugar transporter, putative 0.0032 0.0217 0.0568
Trypanosoma brucei glucose transporter, putative 0.007 0.0621 0.1628
Toxoplasma gondii hypothetical protein 0.0017 0.0061 0.0092
Schistosoma mansoni chromobox protein 0.0069 0.0612 0.0813
Plasmodium falciparum thioredoxin reductase 0.0014 0.0027 0.0025
Schistosoma mansoni nAChR subunit 0.0025 0.0145 0.0191
Trichomonas vaginalis fructose-bisphosphate aldolase, putative 0.0305 0.3115 0.5395
Loa Loa (eye worm) hypothetical protein 0.0174 0.1728 0.2991
Schistosoma mansoni sodium/chloride dependent transporter 0.0022 0.0109 0.0144
Echinococcus multilocularis GPCR, family 2 0.0017 0.0065 0.0085
Brugia malayi bifunctional aminoacyl-tRNA synthetase 0.0067 0.0597 0.1031
Schistosoma mansoni cpg binding protein 0.0033 0.0235 0.0312
Loa Loa (eye worm) ligand-Gated ion Channel family member 0.0025 0.0145 0.0249
Echinococcus granulosus nicotinic acetylcholine receptor alpha subunit 0.0025 0.0145 0.0191
Loa Loa (eye worm) hypothetical protein 0.0017 0.0061 0.0103
Brugia malayi Cytochrome P450 family protein 0.0055 0.0468 0.0809
Brugia malayi Pre-SET motif family protein 0.0218 0.2192 0.3794
Toxoplasma gondii calcium-dependent protein kinase CDPK3 0.0069 0.0615 0.0929
Loa Loa (eye worm) hypothetical protein 0.0025 0.0145 0.0249
Brugia malayi Neurotransmitter-gated ion-channel transmembrane region family protein 0.0025 0.0145 0.0249
Echinococcus multilocularis glycine receptor subunit beta 0.0025 0.0145 0.0191
Trichomonas vaginalis glucosylceramidase, putative 0.0284 0.2892 0.5009
Trypanosoma brucei calcium/calmodulin-dependent protein kinase, putative 0.0069 0.0615 0.1612
Trichomonas vaginalis conserved hypothetical protein 0.0015 0.0042 0.0072
Plasmodium vivax glutathione reductase, putative 0.0039 0.03 0.0299
Loa Loa (eye worm) hypothetical protein 0.004 0.0305 0.0527
Onchocerca volvulus 0.0017 0.0061 0.0237
Echinococcus granulosus calcium:calmodulin dependent protein kinase type 1 0.0069 0.0615 0.0816
Trichomonas vaginalis sugar transporter, putative 0.0032 0.0217 0.0375
Toxoplasma gondii NADPH-glutathione reductase 0.0014 0.0027 0.004
Echinococcus multilocularis glycine receptor subunit beta 0.0025 0.0145 0.0191
Leishmania major protein kinase, putative,polo-like protein kinase, putative 0.0098 0.0918 0.2409
Loa Loa (eye worm) hypothetical protein 0.0032 0.0217 0.0373
Brugia malayi major facilitator superfamily protein 0.0032 0.0217 0.0373
Echinococcus multilocularis Cys loop ligand gated ion channel subunit 0.0025 0.0145 0.0191
Echinococcus multilocularis solute carrier family 22 0.0032 0.0217 0.0287
Trichomonas vaginalis chromodomain helicase DNA binding protein, putative 0.0011 0.0001 0.0002
Brugia malayi hypoxia-induced factor 1 0.0159 0.1572 0.2721
Schistosoma mansoni hypothetical protein 0.002 0.0098 0.0129
Toxoplasma gondii glycyl-tRNA synthetase 0.0013 0.0016 0.0024
Trypanosoma brucei glucose transporter, putative 0.007 0.0621 0.1628
Trichomonas vaginalis CAMK family protein kinase 0.0098 0.0918 0.159
Trichomonas vaginalis conserved hypothetical protein 0.007 0.0621 0.1075
Loa Loa (eye worm) hypothetical protein 0.0025 0.0145 0.0249
Loa Loa (eye worm) hypothetical protein 0.0025 0.0145 0.0249
Mycobacterium leprae Probable lipase LipE 0.004 0.0301 0.2061
Loa Loa (eye worm) norepinephrine transporter 0.0017 0.0061 0.0103
Trypanosoma brucei myo-inositol/proton symporter (MIT) 0.0032 0.0217 0.0568
Loa Loa (eye worm) sugar transporter 0.0032 0.0217 0.0373
Echinococcus multilocularis 3 hydroxyacyl coenzyme A dehydrogenase type 2 0.0119 0.1145 0.1522
Toxoplasma gondii pyruvate dehydrogenase complex subunit PDH-E3II 0.0014 0.0027 0.004
Echinococcus multilocularis Cys loop ligand gated ion channel subunit 0.0011 0.0003 0.0002
Plasmodium vivax calcium-dependent protein kinase 3, putative 0.0069 0.0615 0.0614
Echinococcus granulosus guanine nucleotide binding protein Gs subunit 0.0091 0.0844 0.1122
Brugia malayi Pre-SET motif family protein 0.0032 0.0219 0.0378
Loa Loa (eye worm) hypothetical protein 0.004 0.0301 0.052
Leishmania major prolyl-tRNA synthetase, putative,bifunctional aminoacyl-tRNA synthetase, putative 0.0079 0.0715 0.1876
Schistosoma mansoni lipoxygenase 0.0122 0.1175 0.1563
Echinococcus granulosus sodium dependent neurotransmitter transporter 0.0017 0.0061 0.0079
Onchocerca volvulus 0.0032 0.0217 0.0859
Plasmodium falciparum calcium-dependent protein kinase 4 0.0069 0.0615 0.0614
Loa Loa (eye worm) hypothetical protein 0.0025 0.0145 0.0249
Schistosoma mansoni histone-lysine n-methyltransferase setb1 0.0032 0.0219 0.029
Brugia malayi hypothetical protein 0.0011 0.0003 0.0003
Schistosoma mansoni sugar transporter 0.0032 0.0217 0.0287
Loa Loa (eye worm) ACC-1 protein 0.0025 0.0145 0.0249
Schistosoma mansoni acetylcholine receptor subunit beta 0.0011 0.0003 0.0002
Onchocerca volvulus Peroxidase homolog 0.004 0.0305 0.1212
Mycobacterium ulcerans DNA polymerase IV 0.0019 0.0084 0.0145
Brugia malayi Neurotransmitter-gated ion-channel transmembrane region family protein 0.0025 0.0145 0.0249
Trypanosoma cruzi GTP-binding nuclear protein rtb2, putative 0.0023 0.0129 0.0338
Loa Loa (eye worm) hypothetical protein 0.002 0.0098 0.0167
Echinococcus granulosus glycine receptor subunit beta 0.0025 0.0145 0.0191
Brugia malayi serine/threonine-protein kinase plk-2 0.0098 0.0918 0.1588
Loa Loa (eye worm) hypothetical protein 0.004 0.0305 0.0527
Schistosoma mansoni kinase 0.0052 0.0431 0.0572
Loa Loa (eye worm) major facilitator superfamily transporter 0.0032 0.0217 0.0373
Schistosoma mansoni neurotransmitter gated ion channel 0.0011 0.0003 0.0002
Mycobacterium tuberculosis Cytochrome P450 51 Cyp51 (CYPL1) (P450-L1A1) (sterol 14-alpha demethylase) (lanosterol 14-alpha demethylase) (P450-14DM) 0.0055 0.0468 0.1827
Loa Loa (eye worm) hypothetical protein 0.004 0.0305 0.0527
Echinococcus multilocularis Sugar transporter ERD6 protein 0.0032 0.0217 0.0287
Trichomonas vaginalis sugar transporter, putative 0.0032 0.0217 0.0375
Treponema pallidum NADH oxidase 0.0014 0.0027 0.0035
Echinococcus multilocularis lipoxygenase domain containing protein 0.002 0.0098 0.0129
Plasmodium falciparum LCCL domain-containing protein 0.002 0.0098 0.0097
Trypanosoma cruzi dihydrolipoyl dehydrogenase, putative 0.0014 0.0027 0.007
Echinococcus multilocularis nicotinic acetylcholine receptor subunit alpha 8 0.0025 0.0145 0.0191
Echinococcus granulosus synaptic vesicle 2 protein 0.0032 0.0217 0.0287
Schistosoma mansoni protein kinase 0.0069 0.0615 0.0816
Mycobacterium tuberculosis Probable soluble pyridine nucleotide transhydrogenase SthA (STH) (NAD(P)(+) transhydrogenase [B-specific]) (nicotinamide nucleot 0.0014 0.0027 0.0104
Brugia malayi ImpB/MucB/SamB family protein 0.0019 0.0084 0.0143
Loa Loa (eye worm) PLK/PLK1 protein kinase 0.0098 0.0918 0.1588
Schistosoma mansoni acetylcholine receptor-related 0.0011 0.0003 0.0002
Toxoplasma gondii histone lysine acetyltransferase GCN5-A 0.0047 0.0378 0.0572
Trichomonas vaginalis chromobox protein, putative 0.0042 0.0322 0.0558
Onchocerca volvulus Heterochromatin protein 1 homolog 0.0039 0.0291 0.1156
Echinococcus multilocularis histone lysine N methyltransferase SETMAR 0.0032 0.0219 0.029
Loa Loa (eye worm) hypothetical protein 0.0032 0.0217 0.0373
Loa Loa (eye worm) acetylcholine receptor alpha subunit 0.0025 0.0145 0.0249
Trypanosoma brucei DNA polymerase kappa, putative 0.0019 0.0084 0.022
Schistosoma mansoni protein kinase 0.0069 0.0615 0.0816
Echinococcus granulosus lipoxygenase domain containing protein 0.002 0.0098 0.0129
Entamoeba histolytica glycyl-tRNA synthetase, putative 0.0013 0.0016 0.0046
Schistosoma mansoni nAChR subunit (ShAR1-beta2-like) 0.0025 0.0145 0.0191
Echinococcus granulosus solute carrier family 2 facilitated glucose 0.0225 0.2265 0.3012
Schistosoma mansoni rab6-interacting 0.002 0.0098 0.0129
Loa Loa (eye worm) hypothetical protein 0.004 0.0305 0.0527
Toxoplasma gondii lysine-tRNA ligase 0.005 0.0413 0.0625
Echinococcus granulosus solute carrier family 22 0.0032 0.0217 0.0287
Echinococcus multilocularis cpg binding protein 0.0033 0.0235 0.0312
Loa Loa (eye worm) hypothetical protein 0.0011 0.0003 0.0003
Onchocerca volvulus 0.0032 0.0216 0.0858
Trichomonas vaginalis conserved hypothetical protein 0.0032 0.0217 0.0375
Mycobacterium ulcerans dihydrolipoamide dehydrogenase 0.0014 0.0027 0.0046
Schistosoma mansoni neurotransmitter gated ion channel 0.0011 0.0003 0.0002
Brugia malayi beta-lactamase 0.004 0.0301 0.052
Toxoplasma gondii prolyl-tRNA synthetase (ProRS) 0.0079 0.0715 0.108
Trypanosoma cruzi STE/STE11 serine/threonine-protein kinase, putative 0.0018 0.0072 0.019
Leishmania major carbonic anhydrase-like protein 0.0371 0.3812 1
Brugia malayi Neurotransmitter-gated ion-channel ligand binding domain containing protein 0.0025 0.0145 0.0249
Mycobacterium ulcerans hypothetical protein 0.004 0.0301 0.0522
Echinococcus granulosus Cys loop ligand gated ion channel subunit 0.0025 0.0145 0.0191
Loa Loa (eye worm) hypothetical protein 0.0086 0.0795 0.1376
Trypanosoma brucei DNA polymerase kappa, putative 0.0013 0.0021 0.0055
Trichomonas vaginalis conserved hypothetical protein 0.0011 0.0001 0.0002
Onchocerca volvulus 0.004 0.0301 0.1196
Entamoeba histolytica hypothetical protein 0.0026 0.0154 0.0491
Brugia malayi hypothetical protein 0.0056 0.0476 0.0822
Trichomonas vaginalis soluble guanylate cyclase gcy, putative 0.0013 0.0023 0.0041
Loa Loa (eye worm) acetylcholine receptor protein 0.0011 0.0003 0.0003
Echinococcus multilocularis gcn5proteinral control of amino acid synthesis 0.0159 0.1571 0.2089
Mycobacterium leprae putative cytochrome p450 0.0055 0.0468 0.3204
Echinococcus multilocularis glycyl tRNA synthetase 0.0013 0.0016 0.0019
Schistosoma mansoni nAChR subunit (ShAR1-beta-like) 0.0025 0.0145 0.0191
Mycobacterium ulcerans fructose-bisphosphate aldolase 0.0149 0.1461 0.2531
Echinococcus granulosus 5'partial|histone lysine N methyltransferase SETDB2 0.003 0.02 0.0264
Loa Loa (eye worm) hypothetical protein 0.004 0.0305 0.0527
Echinococcus granulosus snurportin 1 0.0339 0.347 0.4615
Echinococcus granulosus thioredoxin glutathione reductase 0.004 0.0306 0.0405
Mycobacterium ulcerans aldehyde dehydrogenase 0.0126 0.1219 0.2111
Loa Loa (eye worm) hypothetical protein 0.002 0.0098 0.0167
Entamoeba histolytica protein kinase, putative 0.0069 0.0615 0.197
Trypanosoma cruzi STE group serine/threonine-protein kinase, putative 0.0018 0.0072 0.019
Brugia malayi hypothetical protein 0.004 0.0305 0.0527
Schistosoma mansoni family S12 unassigned peptidase (S12 family) 0.004 0.0301 0.0399
Echinococcus granulosus solute carrier family 22 0.0032 0.0217 0.0287
Plasmodium vivax proline--tRNA ligase, putative 0.0079 0.0715 0.0714
Trichomonas vaginalis conserved hypothetical protein 0.0011 0.0001 0.0002
Plasmodium vivax SET domain protein, putative 0.0032 0.0219 0.0218
Trichomonas vaginalis glucosylceramidase, putative 0.0196 0.1963 0.34
Loa Loa (eye worm) hypothetical protein 0.0017 0.0065 0.0111
Trypanosoma cruzi PAS-domain containing phosphoglycerate kinase, putative 0.0013 0.0023 0.0062
Mycobacterium tuberculosis Probable cytochrome P450 123 Cyp123 0.0055 0.0468 0.1827
Echinococcus granulosus glycine receptor subunit alpha 1 0.0025 0.0145 0.0191
Schistosoma mansoni sodium/chloride dependent neurotransmitter transporter 0.0112 0.1064 0.1415
Schistosoma mansoni ran 0.0023 0.0129 0.017
Mycobacterium tuberculosis Probable cytochrome P450 125 Cyp125 0.0055 0.0468 0.1827
Schistosoma mansoni hypothetical protein 0.0037 0.0279 0.0369
Loa Loa (eye worm) O-glycosyl hydrolase family 30 protein 0.0284 0.2892 0.5008
Echinococcus multilocularis solute carrier family 2 facilitated glucose 0.0225 0.2265 0.3012
Echinococcus multilocularis importin subunit beta 1 0.0032 0.0218 0.0288
Trichomonas vaginalis conserved hypothetical protein 0.0013 0.0023 0.0041
Schistosoma mansoni tar DNA-binding protein 0.0063 0.0546 0.0725
Mycobacterium tuberculosis Probable esterase LipL 0.004 0.0301 0.1175
Mycobacterium tuberculosis Probable cytochrome P450 128 Cyp128 0.0055 0.0468 0.1827
Brugia malayi cytochrome P450 0.0055 0.0468 0.0809
Echinococcus multilocularis sodium and chloride dependent glycine 0.0017 0.0061 0.0079
Loa Loa (eye worm) hypothetical protein 0.0011 0.0003 0.0003
Echinococcus multilocularis guanine nucleotide binding protein G(s) subunit 0.0091 0.0844 0.1122
Schistosoma mansoni histone-lysine n-methyltransferase setb1 0.0032 0.0219 0.029
Schistosoma mansoni 3-hydroxyacyl-CoA dehydrogenase 0.0119 0.1145 0.1522
Loa Loa (eye worm) hypothetical protein 0.0032 0.0217 0.0373
Trypanosoma brucei THT1 - hexose transporter, putative 0.007 0.0621 0.1628
Loa Loa (eye worm) hypothetical protein 0.0017 0.0061 0.0103
Toxoplasma gondii protein kinase, putative 0.0636 0.6618 1
Loa Loa (eye worm) glutaminase 0.0556 0.5774 1
Trichomonas vaginalis sugar transporter, putative 0.0032 0.0217 0.0375
Loa Loa (eye worm) hypothetical protein 0.0055 0.0463 0.0799
Echinococcus multilocularis sodium and chloride dependent glycine 0.0017 0.0061 0.0079
Trichomonas vaginalis sugar transporter, putative 0.0032 0.0217 0.0375
Mycobacterium leprae Probable threonyl-tRNA synthetase ThrS (threonine-tRNA synthetase) (ThrRS) (Threonine-tRNA ligase) 0.0013 0.0016 0.0107
Trichomonas vaginalis sugar transporter, putative 0.0032 0.0217 0.0375
Brugia malayi Animal haem peroxidase family protein 0.004 0.0305 0.0527
Mycobacterium ulcerans cytochrome P450 191A3 Cyp191A3 0.0055 0.0468 0.0811
Onchocerca volvulus 0.002 0.0098 0.0385
Trypanosoma brucei DNA polymerase IV, putative 0.0019 0.0084 0.022
Brugia malayi Thioredoxin reductase 0.0039 0.03 0.0518
Toxoplasma gondii hypothetical protein 0.0174 0.1728 0.261
Trichomonas vaginalis importin beta-1, putative 0.0026 0.0154 0.0267
Brugia malayi excitatory GABA receptor EXP-1A 0.0025 0.0145 0.0249
Brugia malayi Latrophilin receptor protein 2 0.0017 0.0065 0.0111
Schistosoma mansoni peroxidasin 0.004 0.0305 0.0404
Trypanosoma brucei DNA polymerase kappa, putative 0.0013 0.0021 0.0055
Loa Loa (eye worm) hypothetical protein 0.0011 0.0003 0.0003
Trichomonas vaginalis esterase, putative 0.004 0.0301 0.0522
Loa Loa (eye worm) carbonic anhydrase 3 0.0371 0.3812 0.6601
Brugia malayi RNA, U transporter 1 0.009 0.0837 0.1448
Loa Loa (eye worm) hypothetical protein 0.0025 0.0145 0.0249
Loa Loa (eye worm) hypothetical protein 0.0017 0.0061 0.0103
Trichomonas vaginalis conserved hypothetical protein 0.0032 0.0217 0.0375
Mycobacterium ulcerans cytochrome P450 126A3 Cyp126A3 0.0055 0.0468 0.0811
Trichomonas vaginalis mercuric reductase, putative 0.0014 0.0027 0.0046
Echinococcus multilocularis aryl hydrocarbon receptor 0.0013 0.0023 0.003
Leishmania major acetoin dehydrogenase e3 component-like protein 0.0014 0.0027 0.007
Trichomonas vaginalis sugar transporter, putative 0.0032 0.0217 0.0375
Mycobacterium ulcerans lipase LipD 0.004 0.0301 0.0522
Echinococcus granulosus GPCR family 2 0.0017 0.0065 0.0085
Schistosoma mansoni gcn5proteinral control of amino-acid synthesis 5-like 2 gcnl2 0.0159 0.1571 0.2089
Entamoeba histolytica hypothetical protein 0.005 0.0413 0.1324
Schistosoma mansoni Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) 0.0091 0.0844 0.1122
Plasmodium falciparum lysine--tRNA ligase 0.005 0.0413 0.0412
Schistosoma mansoni mixed-lineage leukemia protein mll 0.0068 0.0604 0.0802
Loa Loa (eye worm) heterochromatin protein 1 0.0069 0.0612 0.1059
Onchocerca volvulus 0.004 0.0305 0.1212
Trichomonas vaginalis conserved hypothetical protein 0.0011 0.0001 0.0002
Mycobacterium tuberculosis Possible penicillin-binding protein 0.0253 0.2563 1
Trypanosoma cruzi STE group serine/threonine-protein kinase, putative 0.0018 0.0072 0.019
Mycobacterium tuberculosis Probable cytochrome P450 137 Cyp137 0.0055 0.0468 0.1827
Mycobacterium tuberculosis Probable esterase/lipase LipP 0.004 0.0301 0.1175
Trichomonas vaginalis chromodomain-helicase-DNA-binding protein, putative 0.0018 0.0077 0.0133
Giardia lamblia Sugar-proton symporter 0.0032 0.0217 0.0649
Onchocerca volvulus Putative nachr subunit 0.0025 0.0145 0.0573
Trypanosoma brucei glucose transporter 2A 0.007 0.0621 0.1628
Trypanosoma cruzi PAS-domain containing phosphoglycerate kinase, putative 0.0013 0.0023 0.0062
Onchocerca volvulus 0.0043 0.0339 0.1346
Schistosoma mansoni carbonic anhydrase II (carbonate dehydratase II) 0.0371 0.3812 0.507
Schistosoma mansoni rab6-interacting 0.002 0.0098 0.0129
Leishmania major DNA polymerase kappa, putative,DNA polymerase IV, putative 0.0019 0.0084 0.022
Chlamydia trachomatis two component regulatory system sensor histidine kinase 0.0013 0.0023 0.0198
Brugia malayi hypothetical protein 0.0128 0.1237 0.2141
Echinococcus granulosus carbonic anhydrase II 0.0371 0.3812 0.507
Loa Loa (eye worm) hypothetical protein 0.004 0.0301 0.052
Schistosoma mansoni importin beta-1 0.0032 0.0218 0.0288
Echinococcus granulosus Cys loop ligand gated ion channel subunit 0.0011 0.0003 0.0002
Trichomonas vaginalis glucosylceramidase, putative 0.0186 0.1857 0.3216
Trichomonas vaginalis sugar transporter, putative 0.0032 0.0217 0.0375
Trypanosoma brucei DNA polymerase kappa, putative 0.0019 0.0084 0.022
Onchocerca volvulus 0.0017 0.0061 0.0237
Echinococcus multilocularis 0.0055 0.0468 0.0621
Mycobacterium ulcerans cytochrome P450 142A3 Cyp142A3 0.0055 0.0468 0.0811
Mycobacterium ulcerans cytochrome p450 150 cyp150 0.0055 0.0468 0.0811
Brugia malayi follicle stimulating hormone receptor 0.024 0.2423 0.4194
Onchocerca volvulus 0.004 0.0305 0.1212
Mycobacterium ulcerans cytochrome P450 123A3 Cyp123A3 0.0055 0.0468 0.0811
Loa Loa (eye worm) GTP-binding nuclear protein RAN/TC4 0.0023 0.0129 0.0221
Toxoplasma gondii Sodium:neurotransmitter symporter family protein 0.0017 0.0061 0.0092
Echinococcus multilocularis carbonic anhydrase 0.0174 0.1728 0.2297
Mycobacterium tuberculosis Probable threonyl-tRNA synthetase ThrS (threonine-tRNA synthetase)(ThrRS) (threonine-tRNA ligase) 0.0013 0.0016 0.0061
Brugia malayi hypothetical protein 0.0032 0.0217 0.0373
Trypanosoma cruzi hexose transporter, putative 0.0038 0.0286 0.0749
Trypanosoma brucei DNA polymerase kappa, putative 0.0019 0.0084 0.022
Leishmania major hypothetical protein, conserved 0.0056 0.0476 0.1248
Entamoeba histolytica hypothetical protein 0.0013 0.0023 0.0071
Trypanosoma brucei unspecified product 0.0019 0.0084 0.022
Plasmodium falciparum thioredoxin reductase 0.0039 0.03 0.0299
Plasmodium vivax hexose transporter 0.0225 0.2265 0.2264
Plasmodium vivax ataxin-2 like protein, putative 0.0056 0.0476 0.0475
Loa Loa (eye worm) hypothetical protein 0.0025 0.0145 0.0249
Echinococcus multilocularis GTP binding nuclear protein Ran 0.0023 0.0129 0.017
Brugia malayi Blistered cuticle protein 3 0.004 0.0305 0.0527
Entamoeba histolytica fructose-1,6-bisphosphate aldolase, putative 0.0305 0.3115 1
Trypanosoma brucei carbonic anhydrase-like protein 0.0371 0.3812 1
Trichomonas vaginalis glutaminase, putative 0.0556 0.5774 1
Leishmania major glucose transporter, lmgt2 0.007 0.0621 0.1628
Plasmodium vivax mitogen-activated protein kinase 2, putative 0.0364 0.3736 0.3735
Echinococcus multilocularis serotonin transporter 0.0017 0.0061 0.0079
Trichomonas vaginalis bromodomain-containing protein, putative 0.0047 0.0378 0.0655
Schistosoma mansoni hypothetical protein 0.0526 0.5455 0.7257
Brugia malayi Cation transporter family protein 0.0025 0.0145 0.0249
Trichomonas vaginalis conserved hypothetical protein 0.0039 0.0291 0.0504
Leishmania major cytochrome p450-like protein 0.0055 0.0468 0.1228
Trichomonas vaginalis sugar transporter, putative 0.007 0.0621 0.1075
Trichomonas vaginalis adenylate cyclase, putative 0.0013 0.0023 0.0041
Mycobacterium ulcerans cytochrome P450 108B4 Cyp108B4 0.0055 0.0468 0.0811
Onchocerca volvulus Chorion peroxidase homolog 0.004 0.0305 0.1212
Mycobacterium tuberculosis Probable cytochrome P450 140 Cyp140 0.0055 0.0468 0.1827
Schistosoma mansoni cpg binding protein 0.0032 0.0216 0.0286
Entamoeba histolytica serine/threonine protein kinase, putative 0.0098 0.0918 0.2944
Loa Loa (eye worm) calcium/calmodulin-dependent protein kinase ID 0.0069 0.0615 0.1063
Mycobacterium tuberculosis Probable cytochrome P450 136 Cyp136 0.0055 0.0468 0.1827
Schistosoma mansoni sugar transporter 0.0032 0.0217 0.0287
Mycobacterium tuberculosis Probable lipase LipD 0.004 0.0301 0.1175
Loa Loa (eye worm) doublecortin family protein 0.002 0.0098 0.0167
Echinococcus granulosus gamma aminobutyric acid receptor subunit 0.0011 0.0003 0.0002
Leishmania major threonyl-tRNA synthetase, putative 0.0013 0.0016 0.0041
Brugia malayi Heterochromatin protein 1 0.0069 0.0612 0.1059
Onchocerca volvulus Peroxidase homolog 0.004 0.0305 0.1212
Schistosoma mansoni hypothetical protein 0.0017 0.0065 0.0085
Plasmodium falciparum GTP-binding nuclear protein RAN/TC4 0.0023 0.0129 0.0128
Schistosoma mansoni sugar transporter 0.0032 0.0217 0.0287
Schistosoma mansoni ran 0.0023 0.0129 0.017
Trypanosoma brucei polo-like protein kinase 0.0098 0.0918 0.2409
Trichomonas vaginalis CAMK family protein kinase 0.0051 0.0418 0.0723
Loa Loa (eye worm) hypothetical protein 0.0025 0.0145 0.0249
Leishmania major dihydrolipoamide dehydrogenase, putative 0.0014 0.0027 0.007
Loa Loa (eye worm) cytochrome P450 family protein 0.0055 0.0468 0.0809
Loa Loa (eye worm) hypothetical protein 0.0069 0.0615 0.1063
Trypanosoma cruzi carbonic anhydrase-like protein, putative 0.0371 0.3812 1
Echinococcus multilocularis dnaJ subfamily B 0.045 0.4649 0.6185
Loa Loa (eye worm) bifunctional aminoacyl-tRNA synthetase 0.0028 0.0175 0.0301
Loa Loa (eye worm) hypothetical protein 0.0025 0.0145 0.0249
Trichomonas vaginalis conserved hypothetical protein 0.0039 0.0291 0.0504
Trichomonas vaginalis fructose-bisphosphate aldolase, putative 0.0305 0.3115 0.5395
Loa Loa (eye worm) MH2 domain-containing protein 0.0131 0.1273 0.2203
Trichomonas vaginalis conserved hypothetical protein 0.0027 0.0172 0.0297
Mycobacterium leprae Possible short-chain dehydrogenase EphD 0.0013 0.002 0.0136
Mycobacterium tuberculosis Probable dehydrogenase 0.009 0.0836 0.3263
Loa Loa (eye worm) hypothetical protein 0.0011 0.0003 0.0003
Brugia malayi Cam kinase protein 1 0.0069 0.0615 0.1063
Echinococcus granulosus uncharacterized sodium dependent transporter 0.0017 0.0061 0.0079
Trypanosoma brucei dihydrolipoamide dehydrogenase 0.0014 0.0027 0.007
Mycobacterium tuberculosis Probable fructose-bisphosphate aldolase Fba 0.0149 0.1461 0.5701
Schistosoma mansoni DNA polymerase eta 0.0019 0.0084 0.011
Trichomonas vaginalis chromobox protein, putative 0.0011 0.0001 0.0002
Brugia malayi Sugar transporter family protein 0.0032 0.0217 0.0373
Trichomonas vaginalis sugar transporter, putative 0.0032 0.0217 0.0375
Trypanosoma brucei THT1 - hexose transporter, putative 0.007 0.0621 0.1628
Plasmodium vivax calcium-dependent protein kinase 4, putative 0.0069 0.0615 0.0614
Echinococcus granulosus terminal deoxycytidyl transferase rev1 0.0019 0.0084 0.011
Schistosoma mansoni sodium-dependent amino acid transporter 0.0017 0.0061 0.0079
Trichomonas vaginalis D-aminoacylase, putative 0.004 0.0301 0.0522
Plasmodium falciparum glutathione reductase 0.0014 0.0027 0.0025
Echinococcus granulosus cytochrome P450 2K1 0.0055 0.0468 0.0621
Onchocerca volvulus 0.0025 0.0145 0.0573
Echinococcus granulosus RUN 0.002 0.0098 0.0129
Mycobacterium ulcerans cytochrome P450 187A4 Cyp187A4 0.0055 0.0468 0.0811
Trypanosoma brucei importin beta-1 subunit, putative 0.0032 0.0218 0.0571
Loa Loa (eye worm) hypothetical protein 0.0032 0.0217 0.0373
Echinococcus granulosus peroxidasin 0.004 0.0305 0.0404
Echinococcus multilocularis carbonic anhydrase 0.0174 0.1728 0.2297
Brugia malayi chromobox protein homolog 3 0.0039 0.0291 0.0503
Plasmodium vivax thioredoxin reductase, putative 0.0039 0.03 0.0299
Brugia malayi bHLH-PAS transcription factor 0.0038 0.0286 0.0493
Loa Loa (eye worm) Sodium:neurotransmitter symporter family protein 0.0017 0.0061 0.0103
Onchocerca volvulus 0.0032 0.0217 0.0859
Echinococcus granulosus General substrate transporter 0.0193 0.193 0.2566
Mycobacterium ulcerans sugar-transport integral membrane protein SugI 0.0032 0.0217 0.0375
Loa Loa (eye worm) hypothetical protein 0.004 0.0301 0.052
Onchocerca volvulus 0.003 0.0203 0.0804
Trypanosoma brucei dihydrolipoyl dehydrogenase 0.0014 0.0027 0.007
Schistosoma mansoni glutamyl-tRNA synthetase cytoplasmic (glutamate--tRNA ligase) (glurs) 0.0067 0.0597 0.0792
Brugia malayi Eukaryotic-type carbonic anhydrase family protein 0.0174 0.1728 0.2991
Echinococcus multilocularis uncharacterized sodium dependent transporter 0.0017 0.0061 0.0079
Schistosoma mansoni nAChR subunit 0.0025 0.0145 0.0191
Echinococcus multilocularis lysyl tRNA synthetase 0.005 0.0413 0.0549
Echinococcus multilocularis acetylcholine receptor subunit beta 1 0.0025 0.0145 0.0191
Brugia malayi Sodium:neurotransmitter symporter family protein 0.0017 0.0061 0.0103
Onchocerca volvulus 0.0013 0.0023 0.0089
Brugia malayi CXXC zinc finger family protein 0.0032 0.0216 0.0373
Mycobacterium ulcerans cytochrome P450 140A5 Cyp140A5 0.0055 0.0468 0.0811
Trichomonas vaginalis fructose-bisphosphate aldolase, putative 0.0305 0.3115 0.5395
Trypanosoma cruzi PAB1-binding protein , putative 0.0056 0.0476 0.1248
Loa Loa (eye worm) nicotinic acetylcholine receptor alpha subunit 0.0025 0.0145 0.0249
Schistosoma mansoni single-minded 0.0052 0.0428 0.0568
Leishmania major importin beta-1 subunit, putative 0.0026 0.0154 0.0404
Echinococcus granulosus acetylcholine receptor subunit beta 1 0.0025 0.0145 0.0191
Loa Loa (eye worm) hypothetical protein 0.0173 0.1714 0.2967
Brugia malayi MH2 domain containing protein 0.0131 0.1273 0.2203
Loa Loa (eye worm) hypothetical protein 0.0017 0.0061 0.0103
Mycobacterium leprae Possible regulatory protein 0.0013 0.0023 0.0161
Trichomonas vaginalis chromodomain-helicase-DNA-binding protein, putative 0.0015 0.0042 0.0072
Mycobacterium ulcerans cytochrome P450 150A6 Cyp150A6 0.0055 0.0468 0.0811
Schistosoma mansoni cpg binding protein 0.0033 0.0235 0.0312
Mycobacterium tuberculosis Probable cytochrome P450 141 Cyp141 0.0055 0.0468 0.1827
Toxoplasma gondii sugar transporter ST2 0.0032 0.0217 0.0327
Loa Loa (eye worm) hypothetical protein 0.0011 0.0003 0.0003
Loa Loa (eye worm) hypothetical protein 0.0025 0.0145 0.0249
Echinococcus granulosus carbonic anhydrase 0.0174 0.1728 0.2297
Onchocerca volvulus Huntingtin homolog 0.0128 0.1237 0.4927
Mycobacterium ulcerans integral membrane transport protein 0.0032 0.0217 0.0375
Toxoplasma gondii hypothetical protein 0.0017 0.0061 0.0092
Loa Loa (eye worm) CHromoDomain protein family member 0.0013 0.002 0.0033
Trichomonas vaginalis conserved hypothetical protein 0.0011 0.0001 0.0002
Echinococcus granulosus solute carrier family 2 facilitated glucose 0.0225 0.2265 0.3012
Plasmodium falciparum transporter, putative 0.0017 0.0061 0.0059
Loa Loa (eye worm) hypothetical protein 0.0032 0.0217 0.0373
Brugia malayi Major Facilitator Superfamily protein 0.0032 0.0217 0.0373
Trichomonas vaginalis sugar transporter, putative 0.0032 0.0217 0.0375
Loa Loa (eye worm) hypothetical protein 0.004 0.0301 0.052
Loa Loa (eye worm) thioredoxin reductase 0.0039 0.03 0.0518
Schistosoma mansoni aldehyde dehydrogenase 0.0126 0.1219 0.162
Entamoeba histolytica acetyltransferase, GNAT family 0.0043 0.0337 0.1078
Trypanosoma cruzi dihydrolipoamide dehydrogenase, putative 0.0014 0.0027 0.007
Trichomonas vaginalis sugar transporter, putative 0.0032 0.0217 0.0375
Brugia malayi Peroxidasin 0.004 0.0305 0.0527
Mycobacterium tuberculosis Probable cytochrome P450 132 Cyp132 0.0055 0.0468 0.1827
Loa Loa (eye worm) hypothetical protein 0.003 0.0203 0.0349
Mycobacterium tuberculosis Probable epoxide hydrolase EphA (epoxide hydratase) (arene-oxide hydratase) 0.0183 0.1822 0.7107
Plasmodium vivax glycine--tRNA ligase, putative 0.0013 0.0016 0.0014
Plasmodium falciparum protein kinase 7 0.0636 0.6618 0.6618
Loa Loa (eye worm) hypothetical protein 0.0011 0.0003 0.0003
Loa Loa (eye worm) hypothetical protein 0.0025 0.0145 0.0249
Echinococcus granulosus Polycystic kidney disease protein 0.002 0.0098 0.0129
Onchocerca volvulus 0.0025 0.0145 0.0573
Onchocerca volvulus 0.0017 0.0061 0.0237
Wolbachia endosymbiont of Brugia malayi major facilitator superfamily permease 0.0032 0.0217 1
Mycobacterium tuberculosis Probable reductase 0.009 0.0836 0.3263
Mycobacterium ulcerans cytochrome P450 136A2 Cyp136A2 0.0055 0.0468 0.0811
Giardia lamblia Prolyl-tRNA synthetase 0.0067 0.0597 0.1874
Echinococcus multilocularis glycine receptor subunit alpha 1 0.0025 0.0145 0.0191
Schistosoma mansoni nAChR subunit 0.0011 0.0003 0.0002
Brugia malayi Neurotransmitter-gated ion-channel transmembrane region family protein 0.0013 0.0023 0.0038
Mycobacterium tuberculosis Probable cytochrome P450 139 Cyp139 0.0055 0.0468 0.1827
Onchocerca volvulus Peroxidasin homolog 0.004 0.0305 0.1212
Mycobacterium tuberculosis Putative ferredoxin reductase 0.009 0.0836 0.3263
Schistosoma mansoni cytochrome P450 0.0055 0.0468 0.0621
Loa Loa (eye worm) pigment dispersing factor receptor c 0.0055 0.0463 0.0799
Trichomonas vaginalis conserved hypothetical protein 0.0011 0.0001 0.0002
Loa Loa (eye worm) glutamate-gated chloride channel alpha3A subunit 0.0025 0.0145 0.0249
Toxoplasma gondii chromodomain helicase DNA binding protein CHD1/SWI2/SNF2 0.0011 0.0001 0.0002
Trypanosoma brucei DNA polymerase kappa, putative 0.0019 0.0084 0.022
Onchocerca volvulus 0.0032 0.0217 0.0859
Mycobacterium ulcerans lysyl-tRNA synthetase 0.005 0.0413 0.0716
Brugia malayi hypothetical protein 0.002 0.0098 0.0167
Echinococcus multilocularis sodium dependent neurotransmitter transporter 0.0017 0.0061 0.0079
Leishmania major protein kinase, putative 0.0018 0.0072 0.019
Echinococcus granulosus Sugar transporter ERD6 protein 0.0032 0.0217 0.0287
Trypanosoma cruzi Lanosterol 14-alpha demethylase 0.0055 0.0468 0.1228
Loa Loa (eye worm) hypothetical protein 0.004 0.0305 0.0527
Echinococcus multilocularis lipoxygenase domain containing protein 0.002 0.0098 0.0129
Echinococcus multilocularis snurportin 1 0.0339 0.347 0.4615
Brugia malayi Sodium:neurotransmitter symporter family protein 0.0017 0.0061 0.0103
Schistosoma mansoni norepinephrine/norepinephrine transporter 0.0017 0.0061 0.0079
Loa Loa (eye worm) hypothetical protein 0.0011 0.0003 0.0003
Trichomonas vaginalis set domain proteins, putative 0.0248 0.251 0.4346
Mycobacterium tuberculosis Probable cytochrome P450 143 Cyp143 0.0055 0.0468 0.1827
Loa Loa (eye worm) aryl Hydrocarbon receptor Associated protein family member 0.0013 0.0023 0.0039
Echinococcus multilocularis nicotinic acetylcholine receptor subunit type 0.0011 0.0003 0.0002
Trichomonas vaginalis sugar transporter, putative 0.0032 0.0217 0.0375
Brugia malayi glycyl-tRNA synthetase 0.0013 0.0016 0.0025
Trypanosoma cruzi cytochrome p450-like protein, putative 0.0055 0.0468 0.1228
Leishmania major trypanothione reductase 0.0039 0.03 0.0787
Mycobacterium ulcerans fusion protein of transposase for IS2606 and sialic acid-transport integral membrane protein NanT 0.0032 0.0217 0.0375
Loa Loa (eye worm) sugar transporter 0.0225 0.2265 0.3921
Brugia malayi acetylcholine receptor, alpha-type subunit unc-38 precursor 0.0025 0.0145 0.0249
Schistosoma mansoni family S12 unassigned peptidase (S12 family) 0.004 0.0301 0.0399
Plasmodium falciparum calcium-dependent protein kinase 2 0.0069 0.0615 0.0614
Echinococcus granulosus chromobox protein 1 0.0069 0.0612 0.0813
Brugia malayi gamma-aminobutyric-acid receptor beta subunit precursor 0.0025 0.0145 0.0249
Echinococcus granulosus sodium and chloride dependent glycine 0.0017 0.0061 0.0079
Echinococcus granulosus solute carrier family 2 facilitated glucose 0.0225 0.2265 0.3012
Toxoplasma gondii 'chromo' (CHRromatin Organization MOdifier) domain-containing protein 0.0011 0.0001 0.0002
Onchocerca volvulus 0.0025 0.0145 0.0573
Mycobacterium tuberculosis NADPH-dependent mycothiol reductase Mtr 0.0039 0.03 0.1171
Leishmania major protein kinase, putative 0.0069 0.0615 0.1612
Loa Loa (eye worm) hypothetical protein 0.0128 0.1237 0.2141
Trichomonas vaginalis conserved hypothetical protein 0.0011 0.0001 0.0002
Trichomonas vaginalis fructose-bisphosphate aldolase, putative 0.0305 0.3115 0.5395
Echinococcus multilocularis nAChR subunit 0.0025 0.0145 0.0191
Onchocerca volvulus 0.004 0.0301 0.1196
Schistosoma mansoni polycystin 1-related 0.002 0.0098 0.0129
Echinococcus multilocularis microtubule associated protein 2 0.072 0.7517 1
Trichomonas vaginalis Heterochromatin protein, putative 0.0011 0.0001 0.0002
Onchocerca volvulus 0.0032 0.0217 0.0859
Echinococcus multilocularis solute carrier family 2 facilitated glucose 0.0225 0.2265 0.3012
Schistosoma mansoni sodium-dependent neurotransmitter transporter 0.0017 0.0061 0.0079
Echinococcus multilocularis solute carrier family 22 0.0032 0.0217 0.0287
Trypanosoma brucei Lanosterol 14-alpha demethylase 0.0055 0.0468 0.1228
Echinococcus multilocularis geminin 0.0526 0.5455 0.7257
Loa Loa (eye worm) hypothetical protein 0.0017 0.0061 0.0103
Schistosoma mansoni tar DNA-binding protein 0.0063 0.0546 0.0725
Schistosoma mansoni serine/threonine protein kinase 0.0098 0.0918 0.122
Brugia malayi Neurotransmitter-gated ion-channel ligand binding domain containing protein 0.0025 0.0145 0.0249
Loa Loa (eye worm) hypothetical protein 0.004 0.0305 0.0527
Trypanosoma brucei glucose transporter, putative 0.007 0.0621 0.1628
Trypanosoma cruzi prolyl-tRNA synthetase, putative 0.0079 0.0715 0.1876
Leishmania major glucose transporter, lmgt1 0.007 0.0621 0.1628
Onchocerca volvulus 0.0011 0.0001 0.00000005515
Echinococcus granulosus histone acetyltransferase KAT2B 0.0047 0.0378 0.0502
Schistosoma mansoni tar DNA-binding protein 0.0063 0.0546 0.0725
Mycobacterium ulcerans short-chain type dehydrogenase/reductase 0.0119 0.1145 0.1983
Echinococcus granulosus cadherin EGF LAG seven pass G type receptor 0.0017 0.0065 0.0085
Leishmania major protein kinase, putative 0.0018 0.0072 0.019
Onchocerca volvulus 0.0032 0.0217 0.0859
Toxoplasma gondii aldehyde dehydrogenase 0.0126 0.1219 0.1842
Mycobacterium tuberculosis Lysyl-tRNA synthetase 2 LysX 0.0043 0.0333 0.1301
Loa Loa (eye worm) hypothetical protein 0.0025 0.0145 0.0249
Echinococcus granulosus importin subunit beta 1 0.0032 0.0218 0.0288
Echinococcus multilocularis nicotinic acetylcholine receptor alpha subunit 0.0025 0.0145 0.0191
Onchocerca volvulus 0.002 0.0098 0.0385
Loa Loa (eye worm) hypoxia-induced factor 1 0.0159 0.1572 0.2721
Trypanosoma cruzi hexose transporter 0.007 0.0621 0.1628
Trypanosoma cruzi lysyl-tRNA synthetase, putative 0.005 0.0413 0.1085
Echinococcus multilocularis chromobox protein 1 0.0069 0.0612 0.0813
Echinococcus multilocularis diuretic hormone 44 receptor GPRdih2 0.0017 0.0065 0.0085
Mycobacterium tuberculosis Dihydrolipoamide dehydrogenase LpdC (lipoamide reductase (NADH)) (lipoyl dehydrogenase) (dihydrolipoyl dehydrogenase) (diaphoras 0.01 0.0943 0.3679
Echinococcus multilocularis gamma aminobutyric acid receptor subunit 0.0011 0.0003 0.0002
Trichomonas vaginalis chromodomain-helicase-DNA-binding protein, putative 0.0011 0.0001 0.0002
Brugia malayi Putative carbonic anhydrase 5 precursor 0.0371 0.3812 0.6601
Trypanosoma cruzi hexose transporter, putative 0.0032 0.0217 0.0568
Mycobacterium ulcerans glycyl-tRNA synthetase 0.0013 0.0016 0.0027
Brugia malayi Neurotransmitter-gated ion-channel transmembrane region family protein 0.0013 0.0023 0.0038
Schistosoma mansoni glucose transport protein 0.0225 0.2265 0.3012
Brugia malayi hypothetical protein 0.0032 0.0217 0.0373
Trypanosoma cruzi STE/STE11 serine/threonine-protein kinase, putative 0.0018 0.0072 0.019
Trypanosoma brucei glucose transporter, putative 0.007 0.0621 0.1628
Echinococcus multilocularis Polycystic kidney disease protein 0.002 0.0098 0.0129
Echinococcus granulosus GTP binding nuclear protein Ran 0.0023 0.0129 0.017
Trichomonas vaginalis fructose-bisphosphate aldolase, putative 0.0305 0.3115 0.5395
Echinococcus granulosus solute carrier family 22 0.0032 0.0217 0.0287
Echinococcus granulosus dna polymerase eta 0.0019 0.0084 0.011
Schistosoma mansoni Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) 0.0091 0.0844 0.1122
Echinococcus granulosus chromodomain helicase DNA binding protein 4 0.0013 0.002 0.0025
Trichomonas vaginalis CAMK family protein kinase 0.0098 0.0918 0.159
Echinococcus granulosus aldehyde dehydrogenase mitochondrial 0.0126 0.1219 0.162
Trypanosoma brucei GTP-binding nuclear protein rtb2, putative 0.0023 0.0129 0.0338
Trypanosoma cruzi hexose transporter, putative 0.007 0.0621 0.1628
Trichomonas vaginalis Importin beta-1 subunit, putative 0.0026 0.0154 0.0267
Giardia lamblia Histone acetyltransferase GCN5 0.0043 0.0337 0.1037
Onchocerca volvulus Huntingtin homolog 0.0128 0.1237 0.4927
Mycobacterium ulcerans cytochrome P450 188A3 Cyp188A3 0.0055 0.0468 0.0811
Echinococcus granulosus calcium:calmodulin dependent protein kinase type 0.0069 0.0615 0.0816
Trichomonas vaginalis CAMK family protein kinase 0.0098 0.0918 0.159
Schistosoma mansoni hypothetical protein 0.0017 0.0065 0.0085
Brugia malayi Corticotropin releasing factor receptor 2 precursor, putative 0.0055 0.0463 0.0799
Loa Loa (eye worm) hypothetical protein 0.0032 0.0217 0.0373
Loa Loa (eye worm) glutamate-gated chloride channel alpha3A subunit 0.0011 0.0003 0.0003
Plasmodium vivax histone acetyltransferase GCN5, putative 0.0047 0.0378 0.0377
Trypanosoma cruzi glucose transporter, putative 0.0032 0.0217 0.0568
Chlamydia trachomatis proline--tRNA ligase 0.0024 0.0134 0.2978
Trichomonas vaginalis chromodomain helicase DNA binding protein, putative 0.0015 0.0036 0.0063
Echinococcus granulosus lysyl tRNA synthetase 0.005 0.0413 0.0549
Echinococcus granulosus nAChR subunit 0.0025 0.0145 0.0191
Brugia malayi Sodium:neurotransmitter symporter family protein 1, putative 0.0017 0.0061 0.0103
Onchocerca volvulus Glucosylceramidase homolog 0.0186 0.1857 0.7397
Trichomonas vaginalis adenylate cyclase, type VII, putative 0.0013 0.0023 0.0041
Echinococcus granulosus nicotinic acetylcholine receptor a11 subunit 0.0025 0.0145 0.0191
Trypanosoma cruzi polo-like protein kinase, putative 0.0098 0.0918 0.2409
Loa Loa (eye worm) glutathione reductase 0.0039 0.03 0.0518
Plasmodium falciparum dihydrolipoyl dehydrogenase, apicoplast 0.0014 0.0027 0.0025
Loa Loa (eye worm) animal heme peroxidase 0.004 0.0305 0.0527
Mycobacterium leprae Probable fructose bisphosphate aldolase Fba 0.0149 0.1461 1
Trypanosoma cruzi hexose transporter, putative 0.007 0.0621 0.1628
Schistosoma mansoni glucose transport protein 0.0225 0.2265 0.3012
Loa Loa (eye worm) hypothetical protein 0.004 0.0301 0.052
Schistosoma mansoni lysyl-tRNA synthetase 0.005 0.0413 0.0549
Brugia malayi Acetylcholine receptor protein, alpha-like chain 1 precursor 0.0011 0.0003 0.0003
Plasmodium falciparum proline--tRNA ligase 0.0079 0.0715 0.0714
Brugia malayi GTP-binding nuclear protein RAN/TC4 0.0023 0.0129 0.0221
Loa Loa (eye worm) animal heme peroxidase 0.004 0.0305 0.0527
Loa Loa (eye worm) hypothetical protein 0.0039 0.0291 0.0503
Echinococcus granulosus solute carrier family 2 facilitated glucose 0.0225 0.2265 0.3012
Trypanosoma cruzi hypothetical protein, conserved 0.004 0.0301 0.079
Trichomonas vaginalis fructose-bisphosphate aldolase, putative 0.0305 0.3115 0.5395
Onchocerca volvulus 0.0032 0.0217 0.0859
Schistosoma mansoni glutaminase 0.0556 0.5774 0.7681
Brugia malayi glutamate-gated chloride channel alpha3A subunit, putative 0.0013 0.0023 0.0038
Trypanosoma brucei DNA polymerase kappa, putative 0.0019 0.0084 0.022
Echinococcus granulosus nicotinic acetylcholine receptor subunit type 0.0025 0.0145 0.0191
Echinococcus granulosus serotonin transporter 0.0017 0.0061 0.0079
Loa Loa (eye worm) nucleolar RNA-associated protein alpha 0.0339 0.347 0.6008
Toxoplasma gondii calcium-dependent protein kinase CDPK2B 0.0069 0.0615 0.0929
Echinococcus multilocularis synaptic vesicle 2 protein 0.0032 0.0217 0.0287
Trypanosoma brucei cytochrome P450, putative 0.0055 0.0468 0.1228
Loa Loa (eye worm) hypothetical protein 0.0128 0.1237 0.2141
Loa Loa (eye worm) glycyl-tRNA synthetase 0.0013 0.0016 0.0025
Loa Loa (eye worm) hypothetical protein 0.0025 0.0145 0.0249
Toxoplasma gondii Sodium:neurotransmitter symporter family protein 0.0017 0.0061 0.0092
Onchocerca volvulus Peroxidasin homolog 0.004 0.0305 0.1212
Trichomonas vaginalis threonyl-tRNA synthetase, putative 0.0013 0.0016 0.0027
Plasmodium falciparum hexose transporter 0.0225 0.2265 0.2264
Brugia malayi hypothetical protein 0.0011 0.0003 0.0003
Toxoplasma gondii sugar transporter ST1 0.0032 0.0217 0.0327
Mycobacterium tuberculosis Possible cytochrome P450 135B1 Cyp135B1 0.0055 0.0468 0.1827
Schistosoma mansoni sodium-dependent neurotransmitter transporter 0.0017 0.0061 0.0079
Echinococcus multilocularis General substrate transporter 0.0193 0.193 0.2566
Plasmodium falciparum ataxin-2 like protein, putative 0.0056 0.0476 0.0475
Trypanosoma brucei glucose transporter, putative 0.007 0.0621 0.1628
Trypanosoma cruzi dihydrolipoamide dehydrogenase, putative 0.0014 0.0027 0.007
Leishmania major DNA polymerase eta, putative 0.0019 0.0084 0.022
Plasmodium falciparum mitogen-activated protein kinase 2 0.0364 0.3736 0.3735
Echinococcus granulosus Chromobox protein 3 0.0011 0.0001 0.000000018408
Onchocerca volvulus 0.0025 0.0145 0.0573
Echinococcus multilocularis carbonic anhydrase II 0.0371 0.3812 0.507
Loa Loa (eye worm) eukaryotic-type carbonic anhydrase 0.0174 0.1728 0.2991
Mycobacterium tuberculosis Probable lipase LipE 0.004 0.0301 0.1175
Loa Loa (eye worm) hypothetical protein 0.0032 0.0217 0.0373
Echinococcus granulosus nicotinic acetylcholine receptor subunit alpha 8 0.0025 0.0145 0.0191
Trichomonas vaginalis sugar transporter, putative 0.0032 0.0217 0.0375
Onchocerca volvulus Putative transporter 0.0032 0.0217 0.0859
Mycobacterium ulcerans cytochrome P450 187A5 Cyp187A5 0.0055 0.0468 0.0811
Brugia malayi Cytochrome P450 family protein 0.0175 0.1737 0.3008
Trichomonas vaginalis sugar transporter, putative 0.0032 0.0217 0.0375
Loa Loa (eye worm) animal heme peroxidase 0.004 0.0305 0.0527
Plasmodium falciparum amino acid transporter, putative 0.0017 0.0061 0.0059
Loa Loa (eye worm) hypothetical protein 0.004 0.0305 0.0527
Leishmania major lanosterol 14-alpha-demethylase, putative 0.0055 0.0468 0.1228
Leishmania major cytochrome p450-like protein 0.0055 0.0468 0.1228
Trypanosoma cruzi GTP-binding nuclear protein rtb2, putative 0.0023 0.0129 0.0338
Trichomonas vaginalis sugar transporter, putative 0.0032 0.0217 0.0375
Trichomonas vaginalis fructose-bisphosphate aldolase, putative 0.0305 0.3115 0.5395
Trypanosoma brucei threonyl-tRNA synthetase, putative 0.0013 0.0016 0.0041
Trichomonas vaginalis conserved hypothetical protein 0.007 0.0621 0.1075
Schistosoma mansoni lysyl-tRNA synthetase 0.005 0.0413 0.0549
Trichomonas vaginalis sugar transporter, putative 0.0032 0.0217 0.0375
Toxoplasma gondii 'chromo' (CHRromatin Organization MOdifier) domain-containing protein 0.0011 0.0001 0.0002
Echinococcus granulosus serine:threonine protein kinase PLK1 0.0098 0.0918 0.122
Echinococcus granulosus 3 hydroxyacyl coenzyme A dehydrogenase type 2 0.0119 0.1145 0.1522
Schistosoma mansoni tar DNA-binding protein 0.0063 0.0546 0.0725
Chlamydia trachomatis dihydrolipoyl dehydrogenase 0.0014 0.0027 0.0275
Echinococcus granulosus calcium dependent protein kinase 0.0065 0.0566 0.0752
Schistosoma mansoni histone-lysine n-methyltransferase setb1 0.0032 0.0219 0.029
Echinococcus multilocularis tar DNA binding protein 0.0063 0.0546 0.0725
Trypanosoma brucei dihydrolipoamide dehydrogenase 0.0014 0.0027 0.007
Trichomonas vaginalis chromodomain-helicase-DNA-binding protein, putative 0.0011 0.0001 0.0002
Trichomonas vaginalis glucosylceramidase, putative 0.0284 0.2892 0.5009
Trichomonas vaginalis sugar transporter, putative 0.0032 0.0217 0.0375
Echinococcus multilocularis dna polymerase kappa 0.0019 0.0084 0.011
Brugia malayi Eukaryotic-type carbonic anhydrase family protein 0.0371 0.3812 0.6601
Trypanosoma cruzi DNA polymerase kappa, putative 0.0019 0.0084 0.022
Leishmania major glucose transporter, lmgt3 0.007 0.0621 0.1628
Loa Loa (eye worm) hypothetical protein 0.0056 0.0476 0.0822
Schistosoma mansoni sodium/chloride dependent neurotransmitter transporter 0.0112 0.1064 0.1415
Echinococcus granulosus sodium:chloride dependent neurotransmitter 0.0112 0.1064 0.1415
Onchocerca volvulus 0.0011 0.0003 0.0007
Leishmania major hypothetical protein, conserved 0.004 0.0301 0.079
Echinococcus granulosus lipoxygenase domain containing protein 0.002 0.0098 0.0129
Loa Loa (eye worm) hypothetical protein 0.0032 0.0219 0.0378
Trypanosoma cruzi polo-like protein kinase, putative 0.0098 0.0918 0.2409
Echinococcus granulosus chromobox protein 1 0.0069 0.0612 0.0813
Mycobacterium leprae conserved hypothetical protein 0.004 0.0301 0.2061
Trichomonas vaginalis sugar transporter, putative 0.0032 0.0217 0.0375
Loa Loa (eye worm) beta-LACTamase domain containing family member 0.004 0.0301 0.052
Schistosoma mansoni Cys-loop ligand gated ion channel subunit 0.0025 0.0145 0.0191
Loa Loa (eye worm) hypothetical protein 0.0013 0.0023 0.0038
Loa Loa (eye worm) ImpB/MucB/SamB family protein 0.0019 0.0084 0.0143
Loa Loa (eye worm) neuronal acetylcholine receptor protein 0.0011 0.0003 0.0003
Loa Loa (eye worm) hypothetical protein 0.0019 0.0084 0.0143
Trypanosoma brucei glucose transporter 1E 0.007 0.0621 0.1628
Trichomonas vaginalis glucosylceramidase, putative 0.0284 0.2892 0.5009
Trichomonas vaginalis chromobox protein, putative 0.0042 0.0322 0.0558
Echinococcus multilocularis Chromobox protein 3 0.0011 0.0001 0.000000018408
Plasmodium vivax amine transporter, putative 0.0017 0.0061 0.0059
Schistosoma mansoni hypothetical protein 0.0339 0.347 0.4615
Brugia malayi Cation transporter family protein 0.0025 0.0145 0.0249
Toxoplasma gondii LsmAD domain-containing protein 0.0056 0.0476 0.0719
Plasmodium falciparum threonine--tRNA ligase 0.0013 0.0016 0.0014
Loa Loa (eye worm) acetyltransferase 0.0159 0.1571 0.2719
Loa Loa (eye worm) hypothetical protein 0.004 0.0305 0.0527
Trypanosoma brucei DNA polymerase kappa, putative 0.0019 0.0084 0.022
Echinococcus multilocularis calcium dependent protein kinase 0.0065 0.0566 0.0752
Schistosoma mansoni nicotinic acetylcholine receptor alpha 0.0013 0.0023 0.003
Mycobacterium tuberculosis Conserved protein 0.004 0.0301 0.1175
Schistosoma mansoni hypothetical protein 0.0225 0.2265 0.3012
Echinococcus multilocularis Aryl hydrocarbon receptor nuclear 0.0013 0.0023 0.003
Brugia malayi CHD4 protein 0.0013 0.002 0.0033
Loa Loa (eye worm) hypothetical protein 0.0174 0.1728 0.2991
Brugia malayi Neurotransmitter-gated ion-channel ligand binding domain containing protein 0.0011 0.0003 0.0003
Schistosoma mansoni hypothetical protein 0.0025 0.0148 0.0195
Trypanosoma cruzi threonyl-tRNA synthetase, putative 0.0013 0.0016 0.0041
Giardia lamblia Fructose-bisphosphate aldolase 0.0305 0.3115 1
Echinococcus granulosus nAChR subunit 0.0013 0.0023 0.003
Trypanosoma cruzi PAB1-binding protein , putative 0.0056 0.0476 0.1248
Trichomonas vaginalis chromobox protein, putative 0.0011 0.0001 0.0002
Echinococcus granulosus glutamyl tRNA synthetase cytoplasmic 0.0067 0.0597 0.0792
Mycobacterium ulcerans cytochrome P450 143A3 Cyp143A3 0.0055 0.0468 0.0811
Leishmania major GTP-binding protein, putative 0.0023 0.0129 0.0338
Schistosoma mansoni hypothetical protein 0.045 0.4649 0.6185
Echinococcus multilocularis solute carrier family 2, facilitated glucose 0.0225 0.2265 0.3012
Schistosoma mansoni peroxidasin 0.004 0.0305 0.0404
Loa Loa (eye worm) GTP-binding regulatory protein Gs alpha-S chain 0.0091 0.0844 0.146
Loa Loa (eye worm) hypothetical protein 0.0011 0.0003 0.0003
Loa Loa (eye worm) hypothetical protein 0.004 0.0305 0.0527
Brugia malayi acetylcholine receptor protein, alpha-like chain, putative 0.0025 0.0145 0.0249
Brugia malayi Eukaryotic-type carbonic anhydrase family protein 0.0174 0.1728 0.2991
Schistosoma mansoni loxhd1 0.002 0.0098 0.0129
Echinococcus multilocularis peroxidasin 0.004 0.0305 0.0404
Echinococcus multilocularis sodium:chloride dependent neurotransmitter 0.0112 0.1064 0.1415
Plasmodium falciparum calcium-dependent protein kinase 3 0.0069 0.0615 0.0614
Loa Loa (eye worm) hypothetical protein 0.0013 0.0023 0.0038
Echinococcus granulosus tar DNA binding protein 0.0063 0.0546 0.0725
Brugia malayi Calcium/calmodulin-dependent protein kinase type II alpha chain 0.0069 0.0615 0.1063
Brugia malayi Sugar transporter family protein 0.0225 0.2265 0.3921
Trypanosoma brucei glucose transporter, putative 0.007 0.0621 0.1628
Onchocerca volvulus 0.0032 0.0217 0.0859
Schistosoma mansoni chromodomain helicase DNA binding protein 0.0013 0.002 0.0025
Giardia lamblia Lysyl-tRNA synthetase 0.005 0.0413 0.1284
Loa Loa (eye worm) hypothetical protein 0.0067 0.0597 0.1031
Brugia malayi TAR-binding protein 0.0063 0.0546 0.0944
Brugia malayi hypothetical protein 0.0032 0.0217 0.0373
Schistosoma mansoni hypothetical protein 0.0055 0.0468 0.0621
Trichomonas vaginalis sugar transporter, putative 0.0032 0.0217 0.0375
Echinococcus multilocularis terminal deoxycytidyl transferase rev1 0.0019 0.0084 0.011
Echinococcus multilocularis calcium:calmodulin dependent protein kinase type 0.0069 0.0615 0.0816
Schistosoma mansoni Cys-loop ligand gated ion channel subunit 0.0013 0.0023 0.003
Echinococcus granulosus neuronal acetylcholine receptor subunit alpha 4 0.0025 0.0145 0.0191
Mycobacterium leprae Probable lysyl-tRNA synthase LysS (lysine--tRNA ligase 1) (LysRS 1) (lysine translase) 0.0043 0.0333 0.2281
Schistosoma mansoni hypothetical protein 0.0174 0.1728 0.2297
Brugia malayi hypothetical protein 0.0011 0.0003 0.0003
Loa Loa (eye worm) beta-lactamase 0.004 0.0301 0.052
Trichomonas vaginalis sugar transporter, putative 0.0032 0.0217 0.0375
Trypanosoma brucei unspecified product 0.0013 0.0021 0.0055
Loa Loa (eye worm) hypothetical protein 0.0025 0.0145 0.0249
Brugia malayi nicotinic acetylcholine receptor beta-1 chain precursor 0.0025 0.0145 0.0249
Echinococcus granulosus histone lysine methyltransferase setb 0.0032 0.0219 0.029
Onchocerca volvulus 0.0032 0.0217 0.0859
Trichomonas vaginalis conserved hypothetical protein 0.0013 0.0023 0.0041
Schistosoma mansoni tar DNA-binding protein 0.0063 0.0546 0.0725
Onchocerca volvulus 0.004 0.0305 0.1212
Trichomonas vaginalis penicillin-binding protein, putative 0.004 0.0301 0.0522
Trichomonas vaginalis sugar transporter, putative 0.0032 0.0217 0.0375
Mycobacterium ulcerans short chain dehydrogenase 0.0013 0.002 0.0034
Trypanosoma cruzi trypanothione reductase, putative 0.0039 0.03 0.0787
Mycobacterium tuberculosis NAD(P)H quinone reductase LpdA 0.01 0.0943 0.3679
Onchocerca volvulus 0.0032 0.0217 0.0859
Trichomonas vaginalis sugar transporter, putative 0.007 0.0621 0.1075
Loa Loa (eye worm) hypothetical protein 0.0032 0.0217 0.0373
Mycobacterium ulcerans fusion of enoyl-CoA hydratase, EchA21 and lipase, LipE 0.004 0.0301 0.0522
Treponema pallidum fructose-bisphosphate aldolase 0.0305 0.3115 1
Echinococcus multilocularis nAChR subunit 0.0013 0.0023 0.003
Echinococcus multilocularis Threonyl tRNA synthetase, C 0.0013 0.0016 0.0019
Echinococcus granulosus microtubule associated protein 2 0.072 0.7517 1
Trichomonas vaginalis conserved hypothetical protein 0.0011 0.0001 0.0002
Trichomonas vaginalis sugar transporter, putative 0.0032 0.0217 0.0375
Brugia malayi nicotinic acetylcholine receptor alpha subunit, putative 0.0025 0.0145 0.0249
Loa Loa (eye worm) eukaryotic-type carbonic anhydrase 0.0371 0.3812 0.6601
Trypanosoma brucei trypanothione reductase 0.0039 0.03 0.0787
Giardia lamblia Kinase, PLK 0.0098 0.0918 0.2912
Schistosoma mansoni nAChR subunit 0.0011 0.0003 0.0002
Plasmodium falciparum importin beta, putative 0.0032 0.0218 0.0217
Schistosoma mansoni carbonic anhydrase II (carbonate dehydratase II) 0.0371 0.3812 0.507
Echinococcus multilocularis glycine receptor subunit alpha 1 0.0025 0.0145 0.0191
Echinococcus multilocularis arachidonate 5 lipoxygenase 0.0122 0.1175 0.1563
Loa Loa (eye worm) TAR-binding protein 0.0063 0.0546 0.0944
Brugia malayi acetyltransferase, GNAT family protein 0.0159 0.1571 0.2719
Echinococcus multilocularis glycine receptor subunit alpha 1 0.0025 0.0145 0.0191
Mycobacterium tuberculosis Probable short-chain type dehydrogenase/reductase 0.0119 0.1145 0.4468
Echinococcus granulosus nicotinic acetylcholine receptor beta 1 subunit 0.0025 0.0145 0.0191
Trichomonas vaginalis chromodomain helicase DNA binding protein, putative 0.0018 0.0077 0.0133
Loa Loa (eye worm) CYP4Cod1 0.0055 0.0468 0.0809
Entamoeba histolytica deoxycytidyl transferase, putative 0.0019 0.0084 0.0266
Trichomonas vaginalis conserved hypothetical protein 0.0027 0.0172 0.0297
Schistosoma mansoni aldehyde dehydrogenase 0.0126 0.1219 0.162
Echinococcus granulosus Aryl hydrocarbon receptor nuclear 0.0013 0.0023 0.003
Echinococcus granulosus Ataxin 2 N terminaldomain containing protein 0.0025 0.0148 0.0195
Trichomonas vaginalis chromobox protein, putative 0.0011 0.0001 0.0002
Trichomonas vaginalis chromobox protein, putative 0.0069 0.0612 0.1061
Schistosoma mansoni nAChR subunit 0.0025 0.0145 0.0191
Toxoplasma gondii sugar transporter ST3 0.0032 0.0217 0.0327
Mycobacterium ulcerans cytochrome P450 51B1 Cyp51B1 0.0055 0.0468 0.0811
Trichomonas vaginalis hypothetical protein 0.0011 0.0001 0.0002
Trichomonas vaginalis glucosylceramidase, putative 0.0186 0.1857 0.3216
Toxoplasma gondii Sodium:neurotransmitter symporter family protein 0.0017 0.0061 0.0092
Trypanosoma brucei DNA polymerase kappa, putative 0.0019 0.0084 0.022
Loa Loa (eye worm) hypothetical protein 0.0025 0.0145 0.0249
Trypanosoma brucei DNA polymerase eta, putative 0.0019 0.0084 0.022
Mycobacterium ulcerans flavoprotein disulfide reductase 0.0014 0.0027 0.0046
Echinococcus multilocularis calcium:calmodulin dependent protein kinase type 0.0069 0.0615 0.0816
Brugia malayi Neuronal acetylcholine receptor protein, alpha-2 chain precursor 0.0011 0.0003 0.0003
Echinococcus granulosus dnaJ subfamily B 0.045 0.4649 0.6185
Giardia lamblia DINP protein human, muc B family 0.0019 0.0084 0.0221
Giardia lamblia Hexose transporter 0.0032 0.0217 0.0649
Onchocerca volvulus 0.0011 0.0003 0.0007
Schistosoma mansoni glucose transporter 0.0032 0.0217 0.0287
Brugia malayi Hypothetical glycine receptor like protein T20B12.9 in chromosome III 0.0013 0.0023 0.0038
Mycobacterium tuberculosis Cytochrome P450 121 Cyp121 0.0055 0.0468 0.1827
Brugia malayi latrophilin 2 splice variant baaae 0.0037 0.0279 0.0481
Brugia malayi probable proline-trna synthetase - fission yeast, putative 0.0013 0.0016 0.0025
Loa Loa (eye worm) threonyl-tRNA synthetase 0.0013 0.0016 0.0025
Entamoeba histolytica fructose-1,6-bisphosphate aldolase, putative 0.0305 0.3115 1
Trichomonas vaginalis prolyl-tRNA synthetase, putative 0.0067 0.0597 0.1033
Echinococcus multilocularis glutamyl tRNA synthetase cytoplasmic 0.0067 0.0597 0.0792
Trichomonas vaginalis glucose transporter, putative 0.007 0.0621 0.1075
Loa Loa (eye worm) hypothetical protein 0.0055 0.0462 0.0799
Trichomonas vaginalis glucosylceramidase, putative 0.0186 0.1857 0.3216
Echinococcus granulosus glycine receptor subunit alpha 1 0.0025 0.0145 0.0191
Plasmodium vivax sugar transporter, putative 0.0032 0.0217 0.0215
Echinococcus granulosus glycine receptor subunit beta 0.0025 0.0145 0.0191
Trypanosoma brucei DNA polymerase IV, putative 0.0019 0.0084 0.022
Brugia malayi Sodium:neurotransmitter symporter family protein 0.0017 0.0061 0.0103
Giardia lamblia GTP-binding nuclear protein RAN/TC4 0.0023 0.0129 0.0366
Trypanosoma brucei DNA polymerase kappa, putative 0.0019 0.0084 0.022
Brugia malayi Neurotransmitter-gated ion-channel ligand binding domain containing protein 0.0025 0.0145 0.0249
Mycobacterium tuberculosis Possible cytochrome P450 126 Cyp126 0.0055 0.0468 0.1827
Loa Loa (eye worm) solute carrier family 6 member 4 0.0017 0.0061 0.0103
Mycobacterium ulcerans beta-lactamase 0.004 0.0301 0.0522
Trichomonas vaginalis DNA polymerase eta, putative 0.0019 0.0084 0.0145
Mycobacterium tuberculosis Probable conserved lipoprotein 0.004 0.0301 0.1175
Brugia malayi glutamate-gated chloride channel alpha3A subunit, putative 0.0011 0.0003 0.0003
Brugia malayi Cytochrome P450 family protein 0.0055 0.0468 0.0809
Brugia malayi dihydrolipoyl dehydrogenase, mitochondrial precursor, putative 0.0014 0.0027 0.0044
Echinococcus granulosus uncharacterized sodium dependent transporter 0.0017 0.0061 0.0079
Onchocerca volvulus 0.0032 0.0217 0.0859
Schistosoma mansoni chromobox protein 0.0069 0.0612 0.0813
Mycobacterium leprae PROBABLE NADH DEHYDROGENASE NDH 0.009 0.0836 0.5723
Onchocerca volvulus 0.0013 0.0023 0.0089
Loa Loa (eye worm) hypothetical protein 0.0013 0.0023 0.0038
Brugia malayi hypothetical protein 0.0036 0.0265 0.0457
Echinococcus multilocularis nicotinic acetylcholine receptor beta 1 subunit 0.0025 0.0145 0.0191
Trypanosoma cruzi DNA polymerase eta, putative 0.0019 0.0084 0.022
Trichomonas vaginalis sugar transporter, putative 0.0032 0.0217 0.0375
Trypanosoma brucei glucose transporter, putative 0.007 0.0621 0.1628
Trypanosoma cruzi prolyl-tRNA synthetase, putative 0.0079 0.0715 0.1876
Brugia malayi beta-lactamase family protein 0.004 0.0301 0.052
Treponema pallidum sodium- and chloride- dependent transporter 0.0017 0.0061 0.0145
Mycobacterium ulcerans DNA polymerase IV 0.0019 0.0084 0.0145
Trypanosoma cruzi DNA polymerase kappa, putative 0.0019 0.0084 0.022
Loa Loa (eye worm) hypothetical protein 0.0017 0.0061 0.0103
Trichomonas vaginalis glucosylceramidase, putative 0.0284 0.2892 0.5009
Loa Loa (eye worm) hypothetical protein 0.0032 0.0217 0.0373
Brugia malayi Bifunctional aminoacyl-tRNA synthetase 0.0067 0.0597 0.1031
Mycobacterium ulcerans cytochrome P450 185A4 Cyp185A4 0.0055 0.0468 0.0811
Trichomonas vaginalis glucosylceramidase, putative 0.0186 0.1857 0.3216
Echinococcus granulosus carbonic anhydrase 0.0174 0.1728 0.2297
Plasmodium vivax threonine--tRNA ligase, putative 0.0013 0.0016 0.0014
Brugia malayi Neurotransmitter-gated ion-channel ligand binding domain containing protein 0.0025 0.0145 0.0249
Leishmania major 2-oxoglutarate dehydrogenase, e3 component, lipoamidedehydrogenase-like protein 0.0014 0.0027 0.007
Toxoplasma gondii histone lysine acetyltransferase GCN5-B 0.0047 0.0378 0.0572
Onchocerca volvulus 0.004 0.0301 0.1196
Trypanosoma cruzi dihydrolipoyl dehydrogenase, putative 0.0014 0.0027 0.007
Plasmodium vivax dihydrolipoyl dehydrogenase, mitochondrial, putative 0.0014 0.0027 0.0025
Trichomonas vaginalis conserved hypothetical protein 0.0013 0.0023 0.0041
Brugia malayi O-Glycosyl hydrolase family 30 protein 0.0284 0.2892 0.5008
Loa Loa (eye worm) LGC-31 protein 0.0025 0.0145 0.0249
Schistosoma mansoni Cys-loop ligand gated ion channel subunit 0.0025 0.0145 0.0191
Trichomonas vaginalis sugar transporter, putative 0.0032 0.0217 0.0375
Onchocerca volvulus 0.0032 0.0217 0.0859
Loa Loa (eye worm) hypothetical protein 0.0013 0.0023 0.0038
Schistosoma mansoni Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) 0.0091 0.0844 0.1122
Loa Loa (eye worm) hypothetical protein 0.0174 0.1728 0.2991
Trichomonas vaginalis sugar transporter, putative 0.0032 0.0217 0.0375
Leishmania major cytochrome p450-like protein 0.0055 0.0468 0.1228
Toxoplasma gondii cytochrome p450 superfamily protein 0.0055 0.0468 0.0707
Brugia malayi Sodium:neurotransmitter symporter family protein 0.0017 0.0061 0.0103
Loa Loa (eye worm) pre-SET domain-containing protein family protein 0.0218 0.2192 0.3794
Brugia malayi acetylcholine receptor alpha subunit precursor, putative 0.0025 0.0145 0.0249
Trichomonas vaginalis glucosylceramidase, putative 0.0186 0.1857 0.3216
Brugia malayi GTP-binding regulatory protein Gs alpha-S chain, putative 0.0091 0.0844 0.146
Trypanosoma cruzi sugar transporter, putative 0.0032 0.0217 0.0568
Trichomonas vaginalis chromobox protein, putative 0.0069 0.0612 0.1061
Echinococcus multilocularis Ataxin 2, N terminal,domain containing protein 0.0025 0.0148 0.0195
Brugia malayi hypothetical protein 0.0017 0.0061 0.0103
Trichomonas vaginalis Importin beta-1 subunit, putative 0.0026 0.0154 0.0267
Loa Loa (eye worm) latrophilin receptor protein 2 0.0017 0.0065 0.0111
Trichomonas vaginalis myo-inositol transporter, putative 0.0032 0.0217 0.0375
Mycobacterium tuberculosis Possible short-chain dehydrogenase EphD 0.0013 0.002 0.0077
Schistosoma mansoni dihydrolipoamide dehydrogenase 0.0014 0.0027 0.0034
Brugia malayi Major Facilitator Superfamily protein 0.0032 0.0217 0.0373
Brugia malayi Neurotransmitter-gated ion-channel ligand binding domain containing protein 0.0011 0.0003 0.0003
Schistosoma mansoni carbonic anhydrase 0.0174 0.1728 0.2297
Trichomonas vaginalis adenylate and guanylate cyclases, putative 0.0013 0.0023 0.0041
Mycobacterium tuberculosis Probable cytochrome P450 144 Cyp144 0.0055 0.0468 0.1827
Mycobacterium tuberculosis Probable dicarboxylic acid transport integral membrane protein KgtP (dicarboxylate transporter) 0.0032 0.0217 0.0845
Plasmodium falciparum calcium-dependent protein kinase 1 0.0069 0.0615 0.0614
Brugia malayi calcium-independent alpha-latrotoxin receptor 2, putative 0.0017 0.0065 0.0111
Loa Loa (eye worm) cytochrome P450 family protein 0.0175 0.1737 0.3008
Onchocerca volvulus Dual oxidase homolog 0.004 0.0305 0.1212
Echinococcus multilocularis dihydrolipoamide dehydrogenase 0.0014 0.0027 0.0034
Schistosoma mansoni hypothetical protein 0.0017 0.0065 0.0085
Trypanosoma cruzi DNA polymerase kappa, putative 0.0019 0.0084 0.022
Mycobacterium ulcerans prolyl-tRNA synthetase 0.0024 0.0134 0.0232
Schistosoma mansoni glycyl-tRNA synthetase 0.0013 0.0016 0.0019
Mycobacterium tuberculosis Probable aldehyde dehydrogenase 0.0126 0.1219 0.4756
Echinococcus granulosus geminin 0.0526 0.5455 0.7257
Echinococcus multilocularis cadherin EGF LAG seven pass G type receptor 0.0017 0.0065 0.0085
Trypanosoma cruzi hexose transporter, putative 0.007 0.0621 0.1628
Echinococcus granulosus arachidonate 5 lipoxygenase 0.0122 0.1175 0.1563
Brugia malayi PAS domain containing protein 0.0052 0.0428 0.0739
Echinococcus multilocularis calcium:calmodulin dependent protein kinase type 0.0069 0.0615 0.0816
Loa Loa (eye worm) hypothetical protein 0.0032 0.0217 0.0373
Loa Loa (eye worm) hypothetical protein 0.0032 0.0217 0.0373
Schistosoma mansoni hypothetical protein 0.0526 0.5455 0.7257
Trichomonas vaginalis lysyl-tRNA synthetase, putative 0.005 0.0413 0.0716
Plasmodium vivax multidomain scavenger receptor, putative 0.002 0.0098 0.0097
Trypanosoma brucei hypothetical protein, conserved 0.004 0.0301 0.079
Echinococcus granulosus dihydrolipoamide dehydrogenase 0.0014 0.0027 0.0034
Loa Loa (eye worm) hypothetical protein 0.0025 0.0145 0.0249
Mycobacterium tuberculosis Probable NADH dehydrogenase Ndh 0.009 0.0836 0.3263
Brugia malayi RNA recognition motif domain containing protein 0.0063 0.0546 0.0944
Toxoplasma gondii facilitative glucose transporter GT1 0.0225 0.2265 0.3422
Toxoplasma gondii histone lysine methyltransferase SET1 0.0065 0.0569 0.086
Mycobacterium tuberculosis Possible cytochrome P450 135A1 Cyp135A1 0.0055 0.0468 0.1827
Loa Loa (eye worm) CXXC zinc finger family protein 0.0032 0.0216 0.0373
Echinococcus granulosus calcium:calmodulin dependent protein kinase type 0.0069 0.0615 0.0816
Trypanosoma cruzi hypothetical protein, conserved 0.004 0.0301 0.079
Echinococcus granulosus single minded 2 0.0038 0.0286 0.0379
Brugia malayi Calcitonin receptor-like protein seb-1 0.0055 0.0463 0.0799
Plasmodium vivax calcium-dependent protein kinase 1, putative 0.0069 0.0615 0.0614
Trichomonas vaginalis sugar transporter, putative 0.0032 0.0217 0.0375
Trichomonas vaginalis CAMK family protein kinase 0.0098 0.0918 0.159
Loa Loa (eye worm) hypothetical protein 0.004 0.0305 0.0527
Loa Loa (eye worm) hypothetical protein 0.0011 0.0003 0.0003
Trichomonas vaginalis adenylate and guanylate cyclases, putative 0.0013 0.0023 0.0041
Brugia malayi Cation transporter family protein 0.0025 0.0145 0.0249
Trichomonas vaginalis chromodomain helicase DNA binding protein, putative 0.0018 0.0077 0.0133
Mycobacterium ulcerans cytochrome P450 143A4 Cyp143A4 0.0055 0.0468 0.0811
Trichomonas vaginalis CAMK family protein kinase 0.0051 0.0418 0.0723
Trichomonas vaginalis glucosylceramidase, putative 0.0186 0.1857 0.3216
Brugia malayi Cytochrome P450 family protein 0.0055 0.0468 0.0809
Trypanosoma brucei DNA polymerase kappa, putative 0.0019 0.0084 0.022
Trichomonas vaginalis D-aminoacylase, putative 0.004 0.0301 0.0522
Brugia malayi hypothetical protein 0.002 0.0098 0.0167
Schistosoma mansoni lipoxygenase 0.0085 0.0786 0.1044
Brugia malayi Neurotransmitter-gated ion-channel ligand binding domain containing protein 0.0011 0.0003 0.0003
Trichomonas vaginalis chromodomain helicase DNA binding protein, putative 0.0018 0.0077 0.0133
Schistosoma mansoni Cys-loop ligand gated ion channel subunit 0.0025 0.0145 0.0191
Onchocerca volvulus 0.0025 0.0145 0.0573
Loa Loa (eye worm) hypothetical protein 0.0025 0.0145 0.0249
Echinococcus multilocularis thioredoxin glutathione reductase 0.004 0.0306 0.0405
Echinococcus multilocularis solute carrier family 2 facilitated glucose 0.0225 0.2265 0.3012
Brugia malayi Carbonic anhydrase like protein 2 precursor 0.0174 0.1728 0.2991
Trichomonas vaginalis sugar transporter, putative 0.0032 0.0217 0.0375
Schistosoma mansoni carbonic anhydrase-related 0.0174 0.1728 0.2297
Loa Loa (eye worm) hypothetical protein 0.0011 0.0003 0.0003
Loa Loa (eye worm) hypothetical protein 0.0013 0.0023 0.0038
Trichomonas vaginalis ran, putative 0.0023 0.0129 0.0223
Trypanosoma cruzi dihydrolipoamide dehydrogenase, putative 0.0014 0.0027 0.007
Brugia malayi Carbonic anhydrase like protein 2 precursor 0.0174 0.1728 0.2991
Brugia malayi ImpB/MucB/SamB family protein 0.0019 0.0084 0.0143
Brugia malayi hypothetical protein 0.0011 0.0003 0.0003
Entamoeba histolytica Ran family GTPase 0.0023 0.0129 0.041
Trichomonas vaginalis glutathione reductase, putative 0.0014 0.0027 0.0046
Trichomonas vaginalis CAMK family protein kinase 0.0069 0.0615 0.1064
Loa Loa (eye worm) hypothetical protein 0.0013 0.0023 0.0038
Mycobacterium ulcerans cytochrome P450 124A1, Cyp124A1 0.0055 0.0468 0.0811
Echinococcus granulosus solute carrier family 22 0.0032 0.0217 0.0287
Entamoeba histolytica threonyl-tRNA synthetase, putative 0.0013 0.0016 0.0046
Mycobacterium tuberculosis Probable cytochrome P450 124 Cyp124 0.0055 0.0468 0.1827
Brugia malayi hypothetical protein 0.0173 0.1714 0.2967
Onchocerca volvulus 0.0032 0.0217 0.0859
Schistosoma mansoni carbonic anhydrase-related 0.0174 0.1728 0.2297
Brugia malayi glutathione reductase 0.0039 0.03 0.0518
Echinococcus granulosus diuretic hormone 44 receptor GPRdih2 0.0017 0.0065 0.0085
Loa Loa (eye worm) hypothetical protein 0.0011 0.0003 0.0003
Echinococcus multilocularis dna polymerase eta 0.0019 0.0084 0.011
Trichomonas vaginalis sugar transporter, putative 0.0032 0.0217 0.0375
Loa Loa (eye worm) hypothetical protein 0.0067 0.0597 0.1031
Echinococcus granulosus carbonic anhydrase 0.0174 0.1728 0.2297
Trichomonas vaginalis glucosylceramidase, putative 0.0284 0.2892 0.5009
Trichomonas vaginalis CAMK family protein kinase 0.0098 0.0918 0.159
Onchocerca volvulus 0.0011 0.0003 0.0007
Mycobacterium ulcerans dihydrolipoamide dehydrogenase, LpdB 0.0014 0.0027 0.0046
Echinococcus multilocularis aldehyde dehydrogenase, mitochondrial 0.0126 0.1219 0.162
Brugia malayi Animal haem peroxidase family protein 0.004 0.0305 0.0527
Trypanosoma brucei dihydrolipoamide dehydrogenase, point mutation 0.0014 0.0027 0.007
Loa Loa (eye worm) hypothetical protein 0.0011 0.0003 0.0003
Echinococcus granulosus beta LACTamase domain containing family member 0.004 0.0301 0.0399
Plasmodium falciparum calcium-dependent protein kinase 5 0.0069 0.0615 0.0614
Trypanosoma cruzi threonyl-tRNA synthetase, putative 0.0013 0.0016 0.0041
Entamoeba histolytica prolyl-tRNA synthetase, putative 0.0067 0.0597 0.1912
Entamoeba histolytica Acid sphingomyelinase-like phosphodiesterase, putative 0.0086 0.0795 0.255
Trypanosoma brucei DNA polymerase kappa, putative 0.0013 0.0021 0.0055
Wolbachia endosymbiont of Brugia malayi dihydrolipoamide dehydrogenase E3 component 0.0014 0.0027 0.0545
Loa Loa (eye worm) CAMK/CAMK2 protein kinase 0.0069 0.0615 0.1063
Brugia malayi Animal haem peroxidase family protein 0.004 0.0305 0.0527
Schistosoma mansoni aryl hydrocarbon receptor 0.0052 0.0428 0.0568
Loa Loa (eye worm) hypothetical protein 0.004 0.0305 0.0527
Toxoplasma gondii HEAT repeat-containing protein 0.0032 0.0218 0.0329
Brugia malayi Neurotransmitter-gated ion-channel ligand binding domain containing protein 0.0025 0.0145 0.0249
Brugia malayi SET domain containing protein 0.0013 0.0021 0.0034
Mycobacterium ulcerans putative regulatory protein 0.0038 0.0286 0.0495
Mycobacterium ulcerans threonyl-tRNA synthetase 0.0013 0.0016 0.0027
Trichomonas vaginalis sugar transporter, putative 0.0032 0.0217 0.0375
Echinococcus multilocularis calcium:calmodulin dependent protein kinase type 0.0069 0.0615 0.0816
Schistosoma mansoni protein kinase 0.0069 0.0615 0.0816
Loa Loa (eye worm) GABA receptor subunit 0.0013 0.0023 0.0038
Echinococcus granulosus guanine nucleotide binding protein Gs subunit 0.0091 0.0844 0.1122
Onchocerca volvulus 0.0248 0.251 1
Schistosoma mansoni nAChR subunit 0.0025 0.0145 0.0191
Loa Loa (eye worm) hypothetical protein 0.0011 0.0003 0.0003
Plasmodium falciparum histone acetyltransferase GCN5 0.0043 0.0337 0.0336
Echinococcus granulosus calcium:calmodulin dependent protein kinase type 0.0069 0.0615 0.0816
Echinococcus multilocularis guanine nucleotide binding protein G(s) subunit 0.0091 0.0844 0.1122
Trichomonas vaginalis guanylate cyclase, putative 0.0013 0.0023 0.0041
Plasmodium falciparum glutathione reductase 0.0039 0.03 0.0299
Trypanosoma cruzi importin beta-1 subunit, putative 0.0026 0.0154 0.0404
Trypanosoma brucei THT1 - hexose transporter, putative 0.007 0.0621 0.1628
Mycobacterium ulcerans aldehyde dehydrogenase 0.0126 0.1219 0.2111
Mycobacterium ulcerans aldehyde dehydrogenase 0.0126 0.1219 0.2111
Leishmania major glucose transporter/membrane transporter D2, putative 0.007 0.0621 0.1628
Brugia malayi lysyl-tRNA synthetase 0.005 0.0413 0.0714
Trichomonas vaginalis CAMK family protein kinase 0.0098 0.0918 0.159
Onchocerca volvulus Heterochromatin protein 1 homolog 0.0042 0.0322 0.1281
Trypanosoma cruzi DNA polymerase kappa, putative 0.0019 0.0084 0.022
Trichomonas vaginalis DNA polymerase IV / kappa, putative 0.0019 0.0084 0.0145
Echinococcus multilocularis beta LACTamase domain containing family member 0.004 0.0301 0.0399
Loa Loa (eye worm) hypothetical protein 0.0032 0.0217 0.0373
Leishmania major lysyl-tRNA synthetase, putative 0.005 0.0413 0.1085
Loa Loa (eye worm) animal heme peroxidase 0.004 0.0305 0.0527
Loa Loa (eye worm) hypothetical protein 0.0013 0.0023 0.0038
Brugia malayi Importin beta-1 subunit 0.0032 0.0218 0.0375
Loa Loa (eye worm) hypothetical protein 0.004 0.0305 0.0527
Echinococcus granulosus dna polymerase kappa 0.0019 0.0084 0.011
Brugia malayi Eukaryotic-type carbonic anhydrase family protein 0.0174 0.1728 0.2991
Loa Loa (eye worm) transcription factor SMAD2 0.0131 0.1273 0.2203
Chlamydia trachomatis lysine--tRNA ligase 0.005 0.0413 1
Trypanosoma brucei DNA polymerase kappa, putative 0.0019 0.0084 0.022
Onchocerca volvulus 0.0038 0.0286 0.1135
Loa Loa (eye worm) hypothetical protein 0.005 0.0413 0.0714
Trypanosoma brucei PAB1-binding protein , putative 0.0056 0.0476 0.1248
Plasmodium vivax hypothetical protein, conserved 0.0017 0.0061 0.0059
Mycobacterium ulcerans cytochrome P450 144A4 Cyp144A4 0.0055 0.0468 0.0811
Trichomonas vaginalis chromodomain helicase DNA binding protein, putative 0.0018 0.0077 0.0133
Trichomonas vaginalis chromodomain helicase DNA binding protein, putative 0.0018 0.0077 0.0133
Mycobacterium ulcerans epoxide hydrolase EphA 0.0183 0.1822 0.3155
Brugia malayi Doublecortin family protein 0.002 0.0098 0.0167
Echinococcus multilocularis histone lysine methyltransferase setb histone lysine methyltransferase eggless 0.0032 0.0219 0.029
Loa Loa (eye worm) hypothetical protein 0.004 0.0301 0.052
Loa Loa (eye worm) hypothetical protein 0.0011 0.0003 0.0003
Onchocerca volvulus 0.0017 0.0061 0.0237
Mycobacterium tuberculosis Probable hydrolase 0.004 0.0301 0.1175
Echinococcus granulosus glycyl tRNA synthetase 0.0013 0.0016 0.0019
Leishmania major myo-inositol/proton symporter (MIT) 0.0032 0.0217 0.0568
Loa Loa (eye worm) major facilitator superfamily transporter 0.0032 0.0217 0.0373
Loa Loa (eye worm) hypothetical protein 0.0025 0.0145 0.0249
Brugia malayi beta-lactamase family protein 0.004 0.0301 0.052
Mycobacterium tuberculosis Probable cytochrome P450 130 Cyp130 0.0055 0.0468 0.1827
Loa Loa (eye worm) hypothetical protein 0.0025 0.0145 0.0249
Mycobacterium ulcerans cytochrome P450 189A7 Cyp189A7 0.0055 0.0468 0.0811
Trichomonas vaginalis chromodomain-helicase-DNA-binding protein, putative 0.0018 0.0077 0.0133
Plasmodium vivax hypothetical protein, conserved 0.004 0.0301 0.03
Schistosoma mansoni sodium/chloride dependent transporter 0.0017 0.0061 0.0079
Schistosoma mansoni norepinephrine/norepinephrine transporter 0.0017 0.0061 0.0079
Trichomonas vaginalis sugar transporter, putative 0.0032 0.0217 0.0375
Toxoplasma gondii threonyl-tRNA synthetase family protein 0.0013 0.0016 0.0024
Loa Loa (eye worm) hypothetical protein 0.0013 0.0023 0.0038
Schistosoma mansoni nAChR subunit (ShAR1-alpha-like) 0.0025 0.0145 0.0191
Trypanosoma brucei glycyl-tRNA synthetase, putative 0.0013 0.0016 0.0041
Trichomonas vaginalis glucosylceramidase, putative 0.0196 0.1963 0.34
Loa Loa (eye worm) hypothetical protein 0.0032 0.0218 0.0375
Mycobacterium tuberculosis Probable cytochrome P450 138 Cyp138 0.0055 0.0468 0.1827
Trichomonas vaginalis CAMK family protein kinase 0.0098 0.0918 0.159
Mycobacterium leprae Probable prolyl tRNA synthetase ProS 0.0067 0.0597 0.4082
Loa Loa (eye worm) glutaminase 2 0.0556 0.5774 1
Onchocerca volvulus 0.0032 0.0217 0.0859
Schistosoma mansoni sodium/chloride dependent neurotransmitter transporter 0.0112 0.1064 0.1415
Schistosoma mansoni neurotransmitter gated ion channel 0.0013 0.0023 0.003
Echinococcus granulosus histone acetyltransferase KAT2B 0.0155 0.1524 0.2026
Schistosoma mansoni glutamyl-tRNA synthetase cytoplasmic (glutamate--tRNA ligase) (glurs) 0.0067 0.0597 0.0792
Echinococcus granulosus aryl hydrocarbon receptor 0.0013 0.0023 0.003
Echinococcus granulosus cpg binding protein 0.0033 0.0235 0.0312
Mycobacterium leprae Conserved hypothetical protein 0.0055 0.0468 0.3204
Mycobacterium ulcerans esterase/lipase LipP 0.004 0.0301 0.0522
Mycobacterium ulcerans short-chain type dehydrogenase/reductase 0.0119 0.1145 0.1983
Loa Loa (eye worm) cytochrome P450 0.0055 0.0468 0.0809
Loa Loa (eye worm) hypothetical protein 0.0112 0.1064 0.1842
Toxoplasma gondii cell-cycle-associated protein kinase MAPK, putative 0.0364 0.3736 0.5645
Schistosoma mansoni serine/threonine protein kinase 0.0069 0.0615 0.0816
Echinococcus multilocularis transfer RNA-Lys 0.0038 0.0286 0.0379
Echinococcus multilocularis carbonic anhydrase 0.0174 0.1728 0.2297
Leishmania major PAS-domain containing phosphoglycerate kinase, putative 0.0013 0.0023 0.0062
Plasmodium vivax lysine--tRNA ligase, putative 0.005 0.0413 0.0412
Plasmodium falciparum major facilitator superfamily domain-containing protein, putative 0.0032 0.0217 0.0215
Leishmania major dihydrolipoamide dehydrogenase, putative 0.0014 0.0027 0.007
Loa Loa (eye worm) hypothetical protein 0.0017 0.0061 0.0103
Trichomonas vaginalis guanylate cyclase, putative 0.0013 0.0023 0.0041
Loa Loa (eye worm) hypothetical protein 0.0032 0.0217 0.0373
Toxoplasma gondii histone lysine methyltransferase SET/SUV39 0.0032 0.0219 0.0331
Trichomonas vaginalis conserved hypothetical protein 0.0032 0.0217 0.0375
Trypanosoma brucei importin beta-1 subunit, putative 0.0032 0.0218 0.0571
Trichomonas vaginalis cat eye syndrome critical region protein 2, cscr2, putative 0.0047 0.0378 0.0655
Loa Loa (eye worm) blistered cuticle protein 3 0.004 0.0305 0.0527
Mycobacterium tuberculosis Probable oxidoreductase 0.01 0.0943 0.3679
Mycobacterium ulcerans cytochrome P450 125A7 Cyp125A7 0.0055 0.0468 0.0811
Toxoplasma gondii transporter, major facilitator family protein 0.0032 0.0217 0.0327
Entamoeba histolytica Acid sphingomyelinase-like phosphodiesterase, putative 0.0086 0.0795 0.255
Brugia malayi Hypothetical glycine receptor like protein T20B12.9 in chromosome III 0.0025 0.0145 0.0249
Mycobacterium tuberculosis Conserved hypothetical protein 0.0019 0.0084 0.0328
Trypanosoma cruzi dihydrolipoamide dehydrogenase, putative 0.0014 0.0027 0.007
Trichomonas vaginalis sugar transporter, putative 0.0032 0.0217 0.0375
Entamoeba histolytica protein kinase, putative 0.0069 0.0615 0.197
Trichomonas vaginalis adenylate and guanylate cyclases, putative 0.0013 0.0023 0.0041
Plasmodium vivax importin-beta 2, putative 0.0032 0.0218 0.0217
Mycobacterium tuberculosis Conserved protein 0.004 0.0301 0.1175
Trypanosoma cruzi cytochrome P450, putative 0.0055 0.0468 0.1228
Toxoplasma gondii GTP-binding nuclear protein ran/tc4 0.0023 0.0129 0.0195
Treponema pallidum prolyl-tRNA synthetase 0.0024 0.0134 0.0382
Loa Loa (eye worm) Sodium:neurotransmitter symporter family protein 0.0017 0.0061 0.0103
Loa Loa (eye worm) nicotinic acetylcholine receptor non-alpha subunit 0.0025 0.0145 0.0249
Trichomonas vaginalis conserved hypothetical protein 0.0032 0.0217 0.0375
Brugia malayi Animal haem peroxidase family protein 0.004 0.0305 0.0527
Schistosoma mansoni sodium-dependent neurotransmitter transporter 0.0017 0.0061 0.0079
Mycobacterium tuberculosis Probable cytochrome P450 monooxygenase 142 Cyp142 0.0055 0.0468 0.1827
Echinococcus granulosus Threonyl tRNA synthetase C 0.0013 0.0016 0.0019
Trichomonas vaginalis glucose transporter, putative 0.007 0.0621 0.1075
Trichomonas vaginalis sugar transporter, putative 0.007 0.0621 0.1075
Trypanosoma cruzi Lanosterol 14-alpha demethylase 0.0055 0.0468 0.1228
Mycobacterium tuberculosis Possible conserved lipoprotein LpqK 0.004 0.0301 0.1175
Plasmodium vivax calcium-dependent protein kinase, putative 0.0069 0.0615 0.0614
Brugia malayi Sugar transporter family protein 0.0032 0.0217 0.0373
Chlamydia trachomatis Ssodium-dependent amino acid transporter 0.0017 0.0061 0.1132
Leishmania major DNA polymerase kappa, putative 0.0019 0.0084 0.022
Mycobacterium tuberculosis Conserved protein 0.004 0.0301 0.1175
Echinococcus granulosus glycine receptor subunit alpha 1 0.0025 0.0145 0.0191
Schistosoma mansoni rab geranylgeranyl transferase alpha subunit 0.0019 0.0084 0.011
Mycobacterium ulcerans glutaminase 0.0556 0.5774 1
Schistosoma mansoni nAChR subunit 0.0025 0.0145 0.0191
Plasmodium vivax CDK-related protein kinase 6, putative 0.0955 1 1
Trichomonas vaginalis penicillin-binding protein, putative 0.004 0.0301 0.0522
Mycobacterium ulcerans cytochrome P450 105Q4 Cyp105Q4 0.0055 0.0468 0.0811
Trypanosoma cruzi dihydrolipoamide dehydrogenase, putative 0.0014 0.0027 0.007
Mycobacterium tuberculosis Probable membrane NADH dehydrogenase NdhA 0.009 0.0836 0.3263
Brugia malayi hypothetical protein 0.0011 0.0003 0.0003
Trichomonas vaginalis sugar transporter, putative 0.0032 0.0217 0.0375
Brugia malayi Animal haem peroxidase family protein 0.004 0.0305 0.0527
Wolbachia endosymbiont of Brugia malayi dihydrolipoamide dehydrogenase E3 component 0.0014 0.0027 0.0545
Mycobacterium leprae DIHYDROLIPOAMIDE DEHYDROGENASE LPD (LIPOAMIDE REDUCTASE (NADH)) (LIPOYL DEHYDROGENASE) (DIHYDROLIPOYL DEHYDROGENASE) (DIAPHORASE 0.01 0.0943 0.6452
Loa Loa (eye worm) hypothetical protein 0.0017 0.0061 0.0103
Echinococcus multilocularis neuronal acetylcholine receptor subunit alpha 4 0.0025 0.0145 0.0191
Loa Loa (eye worm) 3-hydroxyacyl-CoA dehydrogenase type II 0.0111 0.106 0.1834
Loa Loa (eye worm) cytochrome P450 family protein 0.0055 0.0468 0.0809
Brugia malayi Major Facilitator Superfamily protein 0.0032 0.0217 0.0373
Loa Loa (eye worm) hypothetical protein 0.0011 0.0003 0.0003
Plasmodium vivax dihydrolipoyl dehydrogenase, apicoplast, putative 0.0014 0.0027 0.0025
Loa Loa (eye worm) RNA recognition domain-containing protein domain-containing protein 0.0063 0.0546 0.0944
Schistosoma mansoni terminal deoxycytidyl transferase 0.0019 0.0084 0.011
Loa Loa (eye worm) hypothetical protein 0.0013 0.0016 0.0025
Mycobacterium ulcerans sugar transporter 0.0032 0.0217 0.0375
Trichomonas vaginalis sugar transporter, putative 0.0032 0.0217 0.0375
Loa Loa (eye worm) hypothetical protein 0.0112 0.1064 0.1842
Schistosoma mansoni sugar transporter 0.0032 0.0217 0.0287
Leishmania major prolyl-tRNA synthetase, putative,bifunctional aminoacyl-tRNA synthetase, putative 0.0079 0.0715 0.1876
Trichomonas vaginalis glucose transporter, putative 0.0032 0.0217 0.0375
Loa Loa (eye worm) excitatory GABA receptor EXP-1A 0.0025 0.0145 0.0249
Mycobacterium leprae Possible lysyl-tRNA synthetase 2 LysX 0.005 0.0413 0.283
Onchocerca volvulus 0.0013 0.0023 0.0089
Brugia malayi Neurotransmitter-gated ion-channel ligand binding domain containing protein 0.0025 0.0145 0.0249
Trypanosoma brucei bifunctional aminoacyl-tRNA synthetase, putative 0.0079 0.0715 0.1876
Trypanosoma brucei unspecified product 0.0013 0.0021 0.0055
Echinococcus multilocularis solute carrier family 22 0.0032 0.0217 0.0287
Trichomonas vaginalis sugar transporter, putative 0.0032 0.0217 0.0375
Onchocerca volvulus 0.0032 0.0217 0.0859
Trichomonas vaginalis glucosylceramidase, putative 0.0186 0.1857 0.3216
Leishmania major hypothetical protein, conserved 0.0032 0.0217 0.0568
Plasmodium falciparum dihydrolipoyl dehydrogenase, mitochondrial 0.0014 0.0027 0.0025
Echinococcus multilocularis chromobox protein 1 0.0069 0.0612 0.0813

Activities

Activity type Activity value Assay description Source Reference
MIC (functional) = 9 ug ml-1 Antibacterial activity against Escherichia coli MTCC 739 by modified microtiter broth dilution method ChEMBL. 22677320

Phenotypes

Whole-cell/tissue/organism interactions

We have no records of whole-cell/tissue assays done with this compound What does this mean?

Many chemical entities in TDR Targets come from high-throughput screenings with whole cells or tissue samples, and not all assayed compounds have been tested against a single a single target protein, probably because they get ruled out during screening process. Even if these compounds may have not been of interest in the original screening, they may come as interesting leads for other screening assays. Furthermore, we may be able to propose drug-target associations using chemical similarities and network patterns.

Annotated phenotypes:

We have no manually annotated phenotypes for this drug. What does this mean? / Care to help?
In TDR Targets, information about phenotypes that are caused by drugs, or by genetic manipulation of cells (e.g. gene knockouts or knockdowns) is manually curated from the literature. These descriptions help to describe the potential of the target for drug development. If no information is available for this gene or if the information is incomplete, this may mean that i) the papers containing this information either appeared after the curation effort for this organism was carried out or they were inadvertently missed by curators; or that ii) the curation effort for this organism has not yet started.
 
In any case, if you have information about papers containing relevant validation data for this target, please log in using your TDR Targets username and password and send them to us using the corresponding form in this page (only visible to registered users) or contact us.

External resources for this compound

Bibliographic References

No literature references available for this target.

If you have references for this compound, please enter them in a user comment (below) or Contact us.