Detailed information for compound 1782330

Basic information

Technical information
  • Name: Unnamed compound
  • MW: 601.552 | Formula: C24H26F3N5O8S
  • H donors: 3 H acceptors: 7 LogP: 2.07 Rotable bonds: 10
    Rule of 5 violations (Lipinski): 2
  • SMILES: OC(=O)C(F)(F)F.CCOC(=O)C1CCN(C(=O)C1)c1ccc(cc1)N1C[C@@H](OC1=O)CNC(=O)c1cnc(s1)N
  • InChi: 1S/C22H25N5O6S.C2HF3O2/c1-2-32-20(30)13-7-8-26(18(28)9-13)14-3-5-15(6-4-14)27-12-16(33-22(27)31)10-24-19(29)17-11-25-21(23)34-17;3-2(4,5)1(6)7/h3-6,11,13,16H,2,7-10,12H2,1H3,(H2,23,25)(H,24,29);(H,6,7)/t13?,16-;/m0./s1
  • InChiKey: HAKGUURCZGJXSC-GPPWNDLUSA-N  


Substructure search Similarity search

Network

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Synonyms

No synonyms found for this compound

Targets

Known targets for this compound

No curated genes were found associated with this compound

Predicted pathogen targets for this compound

By orthology
No druggable targets predicted by orthology data
By sequence similarity to non orthologous known druggable targets
No druggable targets predicted by sequence similarity
Obtained from network model

Ranking Plot

Putative Targets List

Species Potential target Raw Global Species
Mycobacterium leprae Possible lysyl-tRNA synthetase 2 LysX 0.0019 0.0028 0.0449
Leishmania major diacylglycerol kinase, putative 0.0081 0.0329 0.2386
Entamoeba histolytica diacylglycerol kinase, putative 0.0081 0.0329 0.0328
Echinococcus granulosus hyperpolarization activated cyclic 0.0015 0.0008 0.0008
Brugia malayi RE15519p 0.0053 0.0193 0.0869
Trichomonas vaginalis Clan CA, family C1, papain-like cysteine peptidase 0.0017 0.0018 0.0079
Loa Loa (eye worm) jmjC domain-containing protein 0.0015 0.0011 0.0011
Echinococcus granulosus SAM and MBT domain containing protein 0.0046 0.0161 0.0161
Plasmodium vivax basic transcription factor 3b, putative 0.0034 0.0103 0.0582
Schistosoma mansoni ankyrin 23/unc44 0.0015 0.0009 0.0007
Schistosoma mansoni ap endonuclease 0.0017 0.002 0.0018
Trichomonas vaginalis flap endonuclease-1, putative 0.0026 0.0061 0.0274
Loa Loa (eye worm) melatonin receptor type 1A 0.0053 0.0193 0.0193
Loa Loa (eye worm) voltage and ligand gated potassium channel 0.0042 0.0139 0.0139
Brugia malayi Dopamine receptor 0.0053 0.0193 0.0869
Toxoplasma gondii histone lysine demethylase JMJD6a 0.0015 0.0011 0.0036
Trichomonas vaginalis sphingosine kinase, putative 0.0081 0.0329 0.1482
Schistosoma mansoni transient receptor potential channel 0.0059 0.0225 0.0224
Brugia malayi ImpB/MucB/SamB family protein 0.0062 0.0236 0.106
Mycobacterium leprae PROBABLE NADH DEHYDROGENASE NDH 0.0079 0.0319 0.5163
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0017 0.0018 0.0079
Trichomonas vaginalis lysyl-tRNA synthetase, putative 0.0019 0.0028 0.0125
Trichomonas vaginalis neutral alpha-glucosidase ab precursor, putative 0.0036 0.0109 0.0492
Leishmania major protein kinase, putative 0.0015 0.0008 0.0057
Loa Loa (eye worm) cyclic-nucleotide gated cation channel 0.0015 0.0008 0.0008
Trichomonas vaginalis chromodomain helicase DNA binding protein, putative 0.0023 0.0049 0.022
Plasmodium falciparum thioredoxin reductase 0.0035 0.0104 0.0587
Echinococcus granulosus pyroglutamylated rfamide peptide receptor 0.0053 0.0193 0.0193
Trichomonas vaginalis fructose-bisphosphate aldolase, putative 0.0287 0.1331 0.6
Schistosoma mansoni protein kinase 0.0026 0.0062 0.006
Echinococcus multilocularis lamin dm0 0.0025 0.0056 0.0056
Loa Loa (eye worm) diacylglycerol kinase 2 0.0081 0.0329 0.0329
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0053 0.0193 0.0192
Loa Loa (eye worm) hypothetical protein 0.0025 0.0056 0.0056
Giardia lamblia Ubiquitin carboxyl-terminal hydrolase 4 0.0036 0.0113 0.071
Trichomonas vaginalis Clan CA, family C1, papain-like cysteine peptidase 0.0017 0.0018 0.0079
Leishmania major protein kinase, putative 0.0026 0.0062 0.0448
Schistosoma mansoni ap endonuclease 0.0017 0.002 0.0018
Entamoeba histolytica glycosyl hydrolase, family 31 protein 0.0036 0.0109 0.0108
Echinococcus granulosus histone lysine N methyltransferase MLL3 0.0015 0.001 0.001
Onchocerca volvulus 0.002 0.0035 0.0247
Onchocerca volvulus 0.0053 0.0193 0.1348
Mycobacterium ulcerans lysyl-tRNA synthetase 0.0019 0.0028 0.0011
Trypanosoma cruzi hexose transporter, putative 0.0014 0.0006 0.0042
Loa Loa (eye worm) TYRA-2 protein 0.0053 0.0193 0.0193
Trypanosoma cruzi diacylglycerol kinase, putative 0.0081 0.0329 0.2386
Echinococcus granulosus short transient receptor potential channel 6 0.0059 0.0225 0.0225
Toxoplasma gondii histone lysine methyltransferase SET/SUV39 0.0031 0.0087 0.0742
Echinococcus multilocularis cathepsin l cysteine peptidase 0.0017 0.0018 0.0018
Echinococcus granulosus NADP dependent isocitrate dehydrogenase 0.0014 0.0007 0.0007
Plasmodium vivax vivapain-2 0.0017 0.0018 0.0066
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0053 0.0193 0.0192
Trichomonas vaginalis conserved hypothetical protein 0.0026 0.0063 0.0285
Onchocerca volvulus 0.0041 0.0138 0.0959
Echinococcus granulosus ferritin 0.0017 0.0017 0.0017
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0017 0.0018 0.0079
Echinococcus multilocularis g protein linked acetylcholine receptor gar 2a 0.0053 0.0193 0.0193
Echinococcus granulosus glutamyl tRNA synthetase cytoplasmic 0.0025 0.0059 0.0059
Onchocerca volvulus 0.0053 0.0193 0.1348
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0053 0.0193 0.0192
Schistosoma mansoni myosin xvIII 0.0053 0.0193 0.0192
Schistosoma mansoni biogenic amine (octopamine/dopamine) receptor 0.0053 0.0193 0.0192
Onchocerca volvulus 0.0053 0.0193 0.1348
Loa Loa (eye worm) hypothetical protein 0.0016 0.0013 0.0013
Echinococcus multilocularis g protein coupled receptor 0.0053 0.0193 0.0193
Echinococcus multilocularis solute carrier family 2 facilitated glucose 0.0084 0.0345 0.0345
Echinococcus multilocularis TRP (transient receptor potential) channel 0.0037 0.0115 0.0115
Loa Loa (eye worm) hypothetical protein 0.0053 0.0193 0.0193
Trypanosoma cruzi diacylglycerol kinase, putative 0.0081 0.0329 0.2386
Loa Loa (eye worm) hypothetical protein 0.0016 0.0013 0.0013
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0064 0.0245 0.1776
Schistosoma mansoni lamin 0.0025 0.0056 0.0055
Brugia malayi CXXC zinc finger family protein 0.0056 0.0209 0.0939
Echinococcus multilocularis g protein coupled receptor 0.0053 0.0193 0.0193
Plasmodium falciparum calcium-dependent protein kinase 2 0.0026 0.0062 0.0331
Echinococcus granulosus rhodopsin orphan GPCR 0.0053 0.0193 0.0193
Toxoplasma gondii histone lysine demethylase JMJC1/KDM5D/JARID1D 0.0015 0.0011 0.0036
Trypanosoma brucei glucose transporter, putative 0.0026 0.0063 0.0453
Loa Loa (eye worm) MH2 domain-containing protein 0.0022 0.0043 0.0043
Schistosoma mansoni alpha-glucosidase 0.0138 0.0606 0.0604
Onchocerca volvulus Neuropeptide F receptor homolog 0.0053 0.0193 0.1348
Schistosoma mansoni sex comb on midleg homolog 0.0046 0.0161 0.016
Echinococcus multilocularis cyclic nucleotide gated cation channel alpha 3 0.0015 0.0008 0.0008
Trypanosoma brucei diacylglycerol kinase, putative 0.0081 0.0329 0.2381
Trichomonas vaginalis glucosylceramidase, putative 0.047 0.2218 1
Echinococcus granulosus MAM 0.0016 0.0013 0.0013
Trypanosoma brucei glucose transporter 2A 0.0026 0.0063 0.0453
Trichomonas vaginalis Clan CA, family C1, papain-like cysteine peptidase 0.0017 0.0018 0.0079
Leishmania major DNA polymerase eta, putative 0.0062 0.0236 0.1711
Leishmania major glycosyl hydrolase-like protein 0.0013 0.0001 0.0006
Echinococcus granulosus rhodopsin orphan GPCR 0.0053 0.0193 0.0193
Echinococcus multilocularis ceramide kinase 0.0081 0.0329 0.0329
Trypanosoma cruzi cytochrome P450, putative 0.002 0.0034 0.0245
Echinococcus multilocularis transcription factor btf3 0.0034 0.0103 0.0103
Trypanosoma cruzi DNA polymerase kappa, putative 0.0037 0.0114 0.0829
Loa Loa (eye worm) cytoplasmic intermediate filament protein 0.0013 0.0001 0.0001
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0017 0.0018 0.0079
Echinococcus granulosus neuropeptide receptor A26 0.0473 0.2231 0.2231
Loa Loa (eye worm) G-protein coupled receptor 0.0053 0.0193 0.0193
Loa Loa (eye worm) hypothetical protein 0.0021 0.0036 0.0036
Echinococcus multilocularis hyperpolarization activated cyclic 0.0015 0.0008 0.0008
Brugia malayi ImpB/MucB/SamB family protein 0.0037 0.0114 0.0512
Mycobacterium tuberculosis Conserved protein 0.2074 1 1
Echinococcus multilocularis Transcription factor, JmjC domain containing protein 0.0057 0.0214 0.0214
Schistosoma mansoni diacylglycerol kinase zeta iota 0.0081 0.0329 0.0327
Echinococcus multilocularis terminal deoxycytidyl transferase rev1 0.0037 0.0114 0.0114
Echinococcus multilocularis growth hormone secretagogue receptor type 1 0.0053 0.0193 0.0193
Echinococcus granulosus g protein coupled receptor 0.0053 0.0193 0.0193
Schistosoma mansoni smad1 5 8 and 0.0022 0.0043 0.0042
Echinococcus granulosus Transcription factor JmjC domain containing protein 0.0057 0.0214 0.0214
Trypanosoma cruzi transcription factor btf3, putative 0.0034 0.0103 0.0751
Plasmodium vivax lysine--tRNA ligase, putative 0.0019 0.0028 0.0127
Echinococcus multilocularis calcium:calmodulin dependent protein kinase type 0.0026 0.0062 0.0062
Loa Loa (eye worm) hypothetical protein 0.0053 0.0193 0.0193
Schistosoma mansoni hypothetical protein 0.0016 0.0013 0.0012
Echinococcus multilocularis General substrate transporter 0.0072 0.0287 0.0287
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0017 0.0018 0.0079
Plasmodium falciparum AP endonuclease (DNA-[apurinic or apyrimidinic site] lyase), putative 0.0017 0.002 0.008
Schistosoma mansoni lipoxygenase 0.0085 0.035 0.0348
Onchocerca volvulus 0.0081 0.0329 0.2292
Brugia malayi diacylglycerol kinase 0.0081 0.0329 0.1479
Schistosoma mansoni ubiquitously transcribed sex (X/Y) chromosome tetratricopeptide repeat protein-related 0.0015 0.0011 0.0009
Schistosoma mansoni transient receptor potential channel 0.0086 0.0353 0.0352
Schistosoma mansoni muscarinic acetylcholine (GAR) receptor 0.0053 0.0193 0.0192
Echinococcus granulosus GPCR family 2 0.0114 0.0488 0.0488
Trypanosoma cruzi flap endonuclease-1 (FEN-1), putative 0.0026 0.0061 0.0442
Schistosoma mansoni rab6-interacting 0.002 0.0035 0.0034
Trichomonas vaginalis Clan CA, family C1, papain-like cysteine peptidase 0.0017 0.0018 0.0079
Schistosoma mansoni jumonji/arid domain-containing protein 0.006 0.0229 0.0228
Loa Loa (eye worm) hypothetical protein 0.0024 0.0054 0.0054
Trypanosoma cruzi mitochondrial DNA polymerase beta, putative 0.0297 0.1377 1
Loa Loa (eye worm) hypothetical protein 0.2074 1 1
Trypanosoma brucei unspecified product 0.0025 0.0059 0.0423
Mycobacterium ulcerans cytochrome P450 185A4 Cyp185A4 0.002 0.0034 0.0017
Echinococcus multilocularis lysyl tRNA synthetase 0.0019 0.0028 0.0028
Trichomonas vaginalis alpha-glucosidase, putative 0.0013 0.0001 0.0004
Echinococcus multilocularis G protein coupled 5 hydroxytryptamine receptor 0.0053 0.0193 0.0193
Schistosoma mansoni lipoxygenase 0.0122 0.0528 0.0526
Schistosoma mansoni retinoblastoma-binding protein 4 (rbbp4) 0.0015 0.0009 0.0008
Echinococcus granulosus rhodopsin orphan GPCR 0.0053 0.0193 0.0193
Onchocerca volvulus Uncharacterized family 31 glucosidase KIAA1161 homolog 0.0013 0.0001 0.0006
Trichomonas vaginalis glucosylceramidase, putative 0.047 0.2218 1
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0017 0.0018 0.0079
Loa Loa (eye worm) intermediate filament protein 0.0025 0.0056 0.0056
Schistosoma mansoni glutamyl-tRNA synthetase cytoplasmic (glutamate--tRNA ligase) (glurs) 0.0025 0.0059 0.0058
Loa Loa (eye worm) hypothetical protein 0.0053 0.0193 0.0193
Loa Loa (eye worm) hypothetical protein 0.0053 0.0193 0.0193
Schistosoma mansoni hypothetical protein 0.0053 0.0193 0.0192
Brugia malayi GnHR receptor homolog 0.0053 0.0193 0.0869
Echinococcus granulosus 7tm_1 domain containing protein 0.0053 0.0193 0.0193
Echinococcus granulosus lysine specific demethylase 5A 0.006 0.0229 0.0229
Trypanosoma brucei flap endonuclease-1 (FEN-1), putative 0.0026 0.0061 0.0436
Echinococcus multilocularis atpase aaa+ type core atpase aaa type core 0.0809 0.3859 0.3859
Echinococcus multilocularis fmrfamide receptor 0.0053 0.0193 0.0193
Echinococcus multilocularis ubiquitin carboxyl terminal hydrolase 8 0.0036 0.0113 0.0113
Brugia malayi bHLH-PAS transcription factor 0.0037 0.0117 0.0525
Toxoplasma gondii NAC domain-containing protein 0.0034 0.0103 0.0893
Echinococcus multilocularis NADP dependent isocitrate dehydrogenase 0.0014 0.0007 0.0007
Onchocerca volvulus 0.0053 0.0193 0.1348
Plasmodium falciparum glutathione reductase 0.0035 0.0104 0.0587
Brugia malayi Inositol-1 0.0038 0.0122 0.0546
Schistosoma mansoni biogenic amine (dopamine) receptor 0.0053 0.0193 0.0192
Brugia malayi Diacylglycerol kinase protein 2 0.0081 0.0329 0.1479
Trypanosoma cruzi myo-inositol-1(or 4)-monophosphatase 1, putative 0.0038 0.0122 0.0884
Schistosoma mansoni smad1 5 8 and 0.0022 0.0043 0.0042
Echinococcus multilocularis cathepsin l cysteine peptidase 0.0017 0.0018 0.0018
Echinococcus multilocularis guanine nucleotide binding protein G(s) subunit 0.0045 0.0156 0.0156
Schistosoma mansoni cyclic-nucleotide-gated cation channel 0.0015 0.0008 0.0007
Trichomonas vaginalis lysyl-tRNA synthetase, putative 0.0016 0.0017 0.0074
Loa Loa (eye worm) cytochrome P450 family protein 0.002 0.0034 0.0034
Schistosoma mansoni peptide (allatostatin)-like receptor 0.0053 0.0193 0.0192
Schistosoma mansoni cyclic-nucleotide-gated cation channel 0.0015 0.0008 0.0007
Echinococcus multilocularis GPCR, family 2 0.0114 0.0488 0.0488
Schistosoma mansoni microtubule-associated protein tau 0.0688 0.3275 0.3274
Loa Loa (eye worm) intermediate filament tail domain-containing protein 0.0025 0.0056 0.0056
Echinococcus multilocularis polycomb protein SCMH1 0.0046 0.0161 0.0161
Loa Loa (eye worm) DEAH box polypeptide 35 0.016 0.0711 0.0711
Loa Loa (eye worm) CHromoDomain protein family member 0.0014 0.0003 0.0003
Loa Loa (eye worm) hypothetical protein 0.0015 0.0009 0.0009
Schistosoma mansoni histone-lysine n-methyltransferase setb1 0.0031 0.0087 0.0085
Loa Loa (eye worm) hypothetical protein 0.0053 0.0193 0.0193
Echinococcus granulosus Peptidase C19 ubiquitin carboxyl terminal hydrolase 2 0.0036 0.0113 0.0113
Mycobacterium leprae Probable prolyl tRNA synthetase ProS 0.0025 0.0059 0.0957
Echinococcus granulosus rhodopsin orphan GPCR 0.0053 0.0193 0.0193
Echinococcus granulosus cyclic nucleotide gated cation channel alpha 3 0.0015 0.0008 0.0008
Loa Loa (eye worm) hypothetical protein 0.0114 0.0488 0.0488
Schistosoma mansoni cyclic-nucleotide-gated cation channel 0.0015 0.0008 0.0007
Leishmania major lysyl-tRNA synthetase, putative 0.0019 0.0028 0.0202
Plasmodium falciparum calcium-dependent protein kinase 4 0.0026 0.0062 0.0331
Echinococcus multilocularis MAM 0.0016 0.0013 0.0013
Mycobacterium tuberculosis Probable membrane NADH dehydrogenase NdhA 0.0079 0.0319 0.0312
Schistosoma mansoni rab6-interacting 0.002 0.0035 0.0034
Echinococcus granulosus intermediate filament protein 0.0025 0.0056 0.0056
Echinococcus granulosus jumonji domain containing 1A 0.0015 0.0011 0.0011
Echinococcus granulosus histone lysine methyltransferase setb 0.0031 0.0087 0.0087
Brugia malayi Bifunctional aminoacyl-tRNA synthetase 0.0025 0.0059 0.0264
Plasmodium vivax proline--tRNA ligase, putative 0.0029 0.0079 0.0438
Trichomonas vaginalis fructose-bisphosphate aldolase, putative 0.0287 0.1331 0.6
Loa Loa (eye worm) hypothetical protein 0.0053 0.0193 0.0193
Leishmania major prolyl-tRNA synthetase, putative,bifunctional aminoacyl-tRNA synthetase, putative 0.0029 0.0079 0.0577
Echinococcus granulosus Ankyrin 0.0015 0.0009 0.0009
Trypanosoma cruzi DNA polymerase eta, putative 0.0036 0.0113 0.0822
Echinococcus multilocularis neuropeptide Y receptor 0.0053 0.0193 0.0193
Trypanosoma cruzi JmjC domain, hydroxylase, putative 0.0015 0.0011 0.0076
Trichomonas vaginalis glucosylceramidase, putative 0.0325 0.1514 0.6826
Mycobacterium ulcerans putative regulatory protein 0.0037 0.0117 0.01
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0064 0.0245 0.1776
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0064 0.0245 0.1776
Leishmania major hypothetical protein, conserved 0.0025 0.0057 0.0413
Trypanosoma cruzi Sphingosine kinase 0.0081 0.0329 0.2386
Wolbachia endosymbiont of Brugia malayi exonuclease III 0.0017 0.002 0.0281
Brugia malayi hypothetical protein 0.0016 0.0013 0.0058
Onchocerca volvulus 0.0015 0.0008 0.0056
Trypanosoma cruzi PAB1-binding protein , putative 0.0025 0.0057 0.0413
Leishmania major DNA polymerase kappa, putative 0.0037 0.0114 0.0829
Brugia malayi Calcitonin receptor-like protein seb-1 0.0359 0.1679 0.757
Echinococcus granulosus tm gpcr rhodopsin 0.0053 0.0193 0.0193
Echinococcus multilocularis somatostatin receptor 0.0053 0.0193 0.0193
Loa Loa (eye worm) hypothetical protein 0.0053 0.0193 0.0193
Trypanosoma cruzi STE/STE11 serine/threonine-protein kinase, putative 0.0015 0.0008 0.0057
Loa Loa (eye worm) hypothetical protein 0.0053 0.0193 0.0193
Loa Loa (eye worm) hypothetical protein 0.0053 0.0193 0.0193
Onchocerca volvulus 0.0015 0.0008 0.0056
Trichomonas vaginalis conserved hypothetical protein 0.0034 0.0103 0.0466
Echinococcus granulosus JmjC domain containing protein 4 0.0015 0.0011 0.0011
Schistosoma mansoni histamine-responsive GPCR (AAF21638) 0.0053 0.0193 0.0192
Brugia malayi Melatonin receptor type 1A 0.0053 0.0193 0.0869
Trypanosoma brucei THT1 - hexose transporter, putative 0.0026 0.0063 0.0453
Brugia malayi Uncoordinated protein 44 0.0015 0.0009 0.0036
Leishmania major cysteine peptidase A (CPA) 0.0017 0.0018 0.0128
Schistosoma mansoni alpha-glucosidase 0.0138 0.0606 0.0604
Trichomonas vaginalis glucosylceramidase, putative 0.0309 0.1433 0.6463
Echinococcus granulosus Ankyrin repeat domain containing protein 0.0082 0.0335 0.0335
Echinococcus multilocularis rhodopsin orphan GPCR 0.0053 0.0193 0.0193
Echinococcus multilocularis TGF beta signal transducer SmadC 0.0022 0.0043 0.0043
Echinococcus multilocularis biogenic amine (5HT) receptor 0.0053 0.0193 0.0193
Plasmodium vivax thioredoxin reductase, putative 0.0035 0.0104 0.0587
Onchocerca volvulus 0.0056 0.0209 0.1457
Plasmodium vivax diacylglycerol kinase, putative 0.0081 0.0329 0.1936
Trypanosoma cruzi hexose transporter 0.0026 0.0063 0.0459
Brugia malayi Dopamine receptor protein 1 0.0053 0.0193 0.0869
Schistosoma mansoni polycystin 1-related 0.002 0.0035 0.0034
Loa Loa (eye worm) hypoxia-induced factor 1 0.0156 0.0691 0.0691
Brugia malayi hypothetical protein 0.0212 0.0966 0.4353
Toxoplasma gondii glycosyl hydrolase, family 31 protein 0.0036 0.0109 0.0946
Echinococcus granulosus nuclear factor of activated T cells 5 0.0076 0.0306 0.0306
Echinococcus granulosus dro:myosuppressin receptor 0.0053 0.0193 0.0193
Trypanosoma cruzi cysteine peptidase, clan CA, family C1, cathepsin L-like, putative 0.0058 0.0218 0.1586
Plasmodium falciparum diacylglycerol kinase, putative 0.0081 0.0329 0.1936
Loa Loa (eye worm) MH1 domain-containing protein 0.0022 0.0043 0.0043
Brugia malayi Muscle positioning protein 4 0.0015 0.0008 0.0033
Toxoplasma gondii protein kinase, putative 0.0238 0.109 1
Toxoplasma gondii calcium-dependent protein kinase CDPK2B 0.0026 0.0062 0.0508
Plasmodium vivax calcium-dependent protein kinase, putative 0.0026 0.0062 0.0331
Loa Loa (eye worm) hypothetical protein 0.0298 0.1383 0.1383
Schistosoma mansoni hypothetical protein 0.0285 0.132 0.1318
Echinococcus granulosus sodium channel protein 0.0047 0.0162 0.0162
Plasmodium vivax multidomain scavenger receptor, putative 0.002 0.0035 0.0173
Entamoeba histolytica hypothetical protein, conserved 0.2074 1 1
Schistosoma mansoni biogenic amine receptor 0.0053 0.0193 0.0192
Echinococcus multilocularis sodium channel protein 0.0047 0.0162 0.0162
Schistosoma mansoni hypothetical protein 0.0291 0.1349 0.1348
Echinococcus multilocularis tachykinin peptides receptor 99D 0.0053 0.0193 0.0193
Echinococcus granulosus g protein linked acetylcholine receptor gar 2a 0.0053 0.0193 0.0193
Brugia malayi Papain family cysteine protease containing protein 0.0017 0.0018 0.0077
Schistosoma mansoni neuropeptide receptor 0.0053 0.0193 0.0192
Brugia malayi neuropeptide F receptor 0.0053 0.0193 0.0869
Echinococcus multilocularis rhodopsin orphan GPCR 0.0053 0.0193 0.0193
Leishmania major alpha glucosidase II subunit, putative 0.0036 0.0109 0.0792
Brugia malayi calcium-independent alpha-latrotoxin receptor 2, putative 0.0114 0.0488 0.2198
Echinococcus granulosus Diacylglycerol kinase zeta 0.0081 0.0329 0.0329
Trypanosoma cruzi cysteine peptidase, putative 0.0064 0.0245 0.1781
Echinococcus multilocularis Diacylglycerol kinase theta 0.0081 0.0329 0.0329
Onchocerca volvulus 0.0037 0.0117 0.0817
Echinococcus multilocularis cpg binding protein 0.0059 0.0224 0.0224
Echinococcus multilocularis cathepsin L cysteine protease 0.0017 0.0018 0.0018
Schistosoma mansoni peptide (FMRFamide/somatostatin)-like receptor 0.0053 0.0193 0.0192
Trichomonas vaginalis fructose-bisphosphate aldolase, putative 0.0287 0.1331 0.6
Trichomonas vaginalis alpha-glucosidase, putative 0.0036 0.0109 0.0492
Echinococcus multilocularis mothers against decapentaplegic 5 0.0022 0.0043 0.0043
Schistosoma mansoni opsin-like receptor 0.0053 0.0193 0.0192
Loa Loa (eye worm) hypothetical protein 0.0037 0.0115 0.0115
Brugia malayi gonadotropin-releasing hormone receptor 2 0.0053 0.0193 0.0869
Trichomonas vaginalis alpha-glucosidase, putative 0.0013 0.0001 0.0004
Trypanosoma brucei isocitrate dehydrogenase [NADP], mitochondrial precursor, putative 0.0014 0.0007 0.0042
Leishmania major isocitrate dehydrogenase [NADP], mitochondrial precursor, putative 0.0014 0.0007 0.0048
Echinococcus multilocularis JmjC domain containing protein 4 0.0015 0.0011 0.0011
Echinococcus granulosus transient receptor potential ion channel A 0.0076 0.0303 0.0303
Trichomonas vaginalis bmru protein, putative 0.0081 0.0329 0.1482
Brugia malayi Cytochrome P450 family protein 0.002 0.0034 0.0149
Schistosoma mansoni neuropeptide receptor 0.0053 0.0193 0.0192
Echinococcus granulosus transient receptor potential gamma protein 0.0086 0.0353 0.0353
Echinococcus multilocularis cyclic nucleotide gated cation channel 0.0015 0.0008 0.0008
Echinococcus multilocularis lamin 0.0025 0.0056 0.0056
Echinococcus multilocularis cathepsin L cysteine protease 0.0017 0.0018 0.0018
Trichomonas vaginalis chromodomain-helicase-DNA-binding protein, putative 0.0017 0.002 0.0091
Echinococcus granulosus 5'partial|histone lysine N methyltransferase SETDB2 0.0029 0.0076 0.0076
Trypanosoma brucei cytochrome P450, putative 0.002 0.0034 0.0239
Echinococcus granulosus lipoxygenase domain containing protein 0.002 0.0035 0.0035
Brugia malayi Corticotropin releasing factor receptor 2 precursor, putative 0.0359 0.1679 0.757
Echinococcus multilocularis lysosomal alpha glucosidase 0.016 0.0714 0.0714
Trichomonas vaginalis conserved hypothetical protein 0.0036 0.0113 0.051
Trypanosoma brucei DNA polymerase IV, putative 0.0037 0.0114 0.0823
Trypanosoma brucei DNA polymerase kappa, putative 0.0025 0.0059 0.0423
Loa Loa (eye worm) ctsf protein 0.0017 0.0018 0.0018
Echinococcus multilocularis solute carrier family 2 facilitated glucose 0.0084 0.0345 0.0345
Trichomonas vaginalis alpha-glucosidase, putative 0.0036 0.0109 0.0492
Leishmania major cathepsin L-like protease 0.0017 0.0018 0.0128
Giardia lamblia Flap structure-specific endonuclease 0.0026 0.0061 0.0312
Plasmodium vivax hexose transporter 0.0084 0.0345 0.2034
Echinococcus multilocularis potassium:sodium hyperpolarization activated 0.0015 0.0008 0.0008
Echinococcus multilocularis potassium voltage gated channel subfamily H 0.0042 0.0139 0.0139
Schistosoma mansoni ancient conserved domain protein 2 (cyclin m2) 0.0053 0.0193 0.0192
Trichomonas vaginalis diacylglycerol kinase, putative 0.0081 0.0329 0.1482
Entamoeba histolytica glycosyl hydrolase, family 31 protein 0.0036 0.0109 0.0108
Echinococcus multilocularis rhodopsin orphan GPCR 0.0053 0.0193 0.0193
Echinococcus multilocularis rhodopsin orphan GPCR 0.0053 0.0193 0.0193
Trichomonas vaginalis glucosylceramidase, putative 0.047 0.2218 1
Mycobacterium ulcerans DNA polymerase IV 0.0037 0.0114 0.0097
Echinococcus granulosus growth hormone secretagogue receptor type 1 0.0053 0.0193 0.0193
Leishmania major trypanothione reductase 0.0035 0.0104 0.0757
Entamoeba histolytica exodeoxyribonuclease III, putative 0.0017 0.002 0.0019
Loa Loa (eye worm) hypothetical protein 0.0013 0.0001 0.0001
Loa Loa (eye worm) glycosyl hydrolase family 31 protein 0.0036 0.0109 0.0109
Brugia malayi hypothetical protein 0.0053 0.0193 0.0869
Loa Loa (eye worm) fibroinase 0.0017 0.0018 0.0018
Trichomonas vaginalis diacylglycerol kinase, zeta, iota, putative 0.0081 0.0329 0.1482
Brugia malayi Cathepsin L-like precursor 0.0017 0.0018 0.0077
Brugia malayi latrophilin 2 splice variant baaae 0.0246 0.1128 0.5083
Schistosoma mansoni hypothetical protein 0.0016 0.0013 0.0012
Trypanosoma brucei isocitrate dehydrogenase, putative 0.0014 0.0007 0.0042
Echinococcus granulosus neuropeptide Y receptor 0.0053 0.0193 0.0193
Onchocerca volvulus 0.0053 0.0193 0.1348
Schistosoma mansoni cathepsin F (C01 family) 0.0017 0.0018 0.0016
Brugia malayi Cyclic-nucleotide gated cation channel 0.0015 0.0008 0.0034
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0017 0.0018 0.0079
Echinococcus multilocularis rhodopsin orphan GPCR 0.0053 0.0193 0.0193
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0017 0.0018 0.0079
Echinococcus multilocularis sex peptide receptor 0.0053 0.0193 0.0193
Brugia malayi Cytochrome P450 family protein 0.002 0.0034 0.0149
Echinococcus granulosus polycomb protein SCMH1 0.0046 0.0161 0.0161
Entamoeba histolytica cysteine proteinase, putative 0.0017 0.0018 0.0017
Schistosoma mansoni Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) 0.0045 0.0156 0.0154
Brugia malayi Dopamine receptor protein 2 0.0053 0.0193 0.0869
Trypanosoma brucei THT1 - hexose transporter, putative 0.0026 0.0063 0.0453
Echinococcus multilocularis calcium:calmodulin dependent protein kinase type 0.0026 0.0062 0.0062
Toxoplasma gondii cell-cycle-associated protein kinase MAPK, putative 0.0136 0.0596 0.5443
Brugia malayi Voltage-gated potassium channel, EAG (KCNH1)-related. C. elegans egl-2 ortholog 0.0018 0.0023 0.0101
Loa Loa (eye worm) hypothetical protein 0.0081 0.0329 0.0329
Toxoplasma gondii flap structure-specific endonuclease 1, putative 0.0026 0.0061 0.05
Echinococcus granulosus g protein linked acetylcholine receptor gar 2a 0.0053 0.0193 0.0193
Trichomonas vaginalis Clan CA, family C1, cathepsin L or K-like cysteine peptidase 0.0017 0.0018 0.0079
Schistosoma mansoni opsin-like receptor 0.0053 0.0193 0.0192
Schistosoma mansoni ubiquitin-specific peptidase 2 (C19 family) 0.0036 0.0113 0.0111
Trichomonas vaginalis ap endonuclease, putative 0.0017 0.002 0.009
Schistosoma mansoni proteasome subunit alpha 6 (T01 family) 0.0081 0.0329 0.0327
Schistosoma mansoni ferritin light chain 0.0017 0.0017 0.0015
Echinococcus multilocularis transient receptor potential ion channel A 0.0076 0.0303 0.0303
Brugia malayi Ceramide kinase 0.0081 0.0329 0.1479
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0064 0.0245 0.1776
Schistosoma mansoni hypothetical protein 0.0084 0.0345 0.0343
Loa Loa (eye worm) hypothetical protein 0.0053 0.0193 0.0193
Echinococcus granulosus guanine nucleotide binding protein Gs subunit 0.0045 0.0156 0.0156
Plasmodium falciparum JmjC domain-containing protein, putative 0.0015 0.0011 0.0023
Schistosoma mansoni amine GPCR 0.0053 0.0193 0.0192
Loa Loa (eye worm) hypothetical protein 0.0053 0.0193 0.0193
Onchocerca volvulus 0.0092 0.0385 0.2688
Loa Loa (eye worm) hypothetical protein 0.0053 0.0193 0.0193
Echinococcus multilocularis rhodopsin orphan GPCR 0.0053 0.0193 0.0193
Loa Loa (eye worm) hypothetical protein 0.0025 0.0059 0.0059
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0064 0.0245 0.1776
Toxoplasma gondii diacylglycerol kinase, putative 0.0081 0.0329 0.2972
Brugia malayi isocitrate dehydrogenase 0.0014 0.0007 0.0027
Plasmodium vivax CDK-related protein kinase 6, putative 0.0357 0.1669 1
Plasmodium vivax glutathione reductase, putative 0.0035 0.0104 0.0587
Entamoeba histolytica diacylglycerol kinase, putative 0.0081 0.0329 0.0328
Leishmania major apurinic/apyrimidinic endonuclease-redox protein 0.0017 0.002 0.0145
Echinococcus granulosus tumor protein p63 0.0349 0.163 0.163
Onchocerca volvulus 0.0015 0.0008 0.0056
Onchocerca volvulus 0.0017 0.0018 0.0123
Loa Loa (eye worm) flap endonuclease-1 0.0026 0.0061 0.0061
Schistosoma mansoni voltage-gated potassium channel 0.0015 0.0008 0.0007
Echinococcus granulosus Polycystic kidney disease protein 0.002 0.0035 0.0035
Mycobacterium ulcerans lysyl-tRNA synthetase 0.0019 0.0028 0.0011
Loa Loa (eye worm) hypothetical protein 0.0018 0.0023 0.0023
Schistosoma mansoni phd/f-box containing protein 0.0015 0.0011 0.0009
Mycobacterium ulcerans extragenic suppressor protein SuhB 0.0038 0.0122 0.0105
Echinococcus granulosus voltage gated sodium channel Nav1 alpha subunit 0.0047 0.0162 0.0162
Loa Loa (eye worm) hypothetical protein 0.0053 0.0193 0.0193
Echinococcus multilocularis cysteine protease 0.0017 0.0018 0.0018
Toxoplasma gondii ImpB/MucB/SamB family protein 0.0036 0.0113 0.0984
Trypanosoma cruzi lysyl-tRNA synthetase, putative 0.0019 0.0028 0.0202
Echinococcus granulosus endonuclease exonuclease phosphatase 0.0186 0.0839 0.0839
Echinococcus multilocularis pyroglutamylated rfamide peptide receptor 0.0053 0.0193 0.0193
Echinococcus multilocularis neuropeptide receptor 0.0053 0.0193 0.0193
Echinococcus multilocularis histone lysine methyltransferase setb histone lysine methyltransferase eggless 0.0031 0.0087 0.0087
Loa Loa (eye worm) hypothetical protein 0.0062 0.0236 0.0236
Trichomonas vaginalis glucosylceramidase, putative 0.047 0.2218 1
Plasmodium falciparum cysteine proteinase falcipain 2a 0.0017 0.0018 0.0066
Mycobacterium leprae DIHYDROLIPOAMIDE DEHYDROGENASE LPD (LIPOAMIDE REDUCTASE (NADH)) (LIPOYL DEHYDROGENASE) (DIHYDROLIPOYL DEHYDROGENASE) (DIAPHORASE 0.0088 0.0362 0.5854
Trypanosoma cruzi Diacylglycerol kinase catalytic domain containing protein, putative 0.0081 0.0329 0.2386
Onchocerca volvulus 0.0053 0.0193 0.1348
Leishmania major DNA polymerase eta, putative 0.0036 0.0113 0.0822
Loa Loa (eye worm) exodeoxyribonuclease III family protein 0.0017 0.002 0.002
Trichomonas vaginalis diacylglycerol kinase, putative 0.0081 0.0329 0.1482
Loa Loa (eye worm) hypothetical protein 0.0092 0.0385 0.0385
Onchocerca volvulus Cathepsin L homolog 0.0017 0.0018 0.0123
Brugia malayi hypothetical protein 0.0081 0.0329 0.1479
Onchocerca volvulus 0.0053 0.0193 0.1348
Brugia malayi MH2 domain containing protein 0.0022 0.0043 0.0193
Onchocerca volvulus 0.0238 0.1089 0.7598
Echinococcus granulosus biogenic amine 5HT receptor 0.0298 0.1383 0.1383
Mycobacterium tuberculosis Probable oxidoreductase 0.0088 0.0362 0.0355
Loa Loa (eye worm) hypothetical protein 0.0019 0.0028 0.0028
Trypanosoma brucei DNA polymerase kappa, putative 0.0037 0.0114 0.0823
Trichomonas vaginalis glucosylceramidase, putative 0.047 0.2218 1
Loa Loa (eye worm) follicle stimulating hormone receptor 0.0053 0.0193 0.0193
Echinococcus granulosus diuretic hormone 44 receptor GPRdih2 0.0114 0.0488 0.0488
Loa Loa (eye worm) hypothetical protein 0.0053 0.0193 0.0193
Leishmania major myo-inositol-1(or 4)-monophosphatase 1, putative 0.0038 0.0122 0.0884
Echinococcus multilocularis SAM and MBT domain containing protein 0.0046 0.0161 0.0161
Echinococcus multilocularis serotonin receptor 0.0298 0.1383 0.1383
Onchocerca volvulus 0.0016 0.0013 0.0094
Echinococcus granulosus acylglycerol kinase mitochondrial 0.0081 0.0329 0.0329
Schistosoma mansoni ubiquitin-specific peptidase 8 (C19 family) 0.0036 0.0113 0.0111
Trichomonas vaginalis alpha-glucosidase, putative 0.0013 0.0001 0.0004
Echinococcus multilocularis ubiquitin specific protease 41 0.0036 0.0113 0.0113
Echinococcus multilocularis isocitrate dehydrogenase 0.0014 0.0007 0.0007
Schistosoma mansoni biogenic amine receptor 0.0053 0.0193 0.0192
Loa Loa (eye worm) hypothetical protein 0.0025 0.0059 0.0059
Onchocerca volvulus Polycomb protein Sfmbt homolog 0.0046 0.0161 0.1126
Schistosoma mansoni neuropeptide F-like receptor 0.0053 0.0193 0.0192
Plasmodium vivax calcium-dependent protein kinase 4, putative 0.0026 0.0062 0.0331
Schistosoma mansoni sphingosine kinase A B 0.2074 1 1
Schistosoma mansoni TGF-beta signal transducer Smad2 0.0022 0.0043 0.0042
Brugia malayi Isocitrate dehydrogenase 0.0014 0.0007 0.0027
Mycobacterium tuberculosis Putative ferredoxin reductase 0.0079 0.0319 0.0312
Echinococcus granulosus expressed protein 0.0017 0.0017 0.0017
Echinococcus multilocularis serotonin receptor 0.0298 0.1383 0.1383
Schistosoma mansoni mixed-lineage leukemia protein mll 0.0015 0.001 0.0008
Trichomonas vaginalis glucosylceramidase, putative 0.0325 0.1514 0.6826
Loa Loa (eye worm) hypothetical protein 0.0053 0.0193 0.0193
Trypanosoma cruzi diacylglycerol kinase-like protein, putative 0.0081 0.0329 0.2386
Plasmodium falciparum protein kinase 7 0.0238 0.109 0.6516
Mycobacterium tuberculosis Inositol-1-monophosphatase SuhB 0.0034 0.0102 0.0096
Brugia malayi M-phase phosphoprotein, mpp8 0.0092 0.0385 0.1735
Onchocerca volvulus Dopamine\/Ecdysteroid receptor homolog 0.0053 0.0193 0.1348
Schistosoma mansoni glucose transport protein 0.0084 0.0345 0.0343
Echinococcus granulosus lamin dm0 0.0025 0.0056 0.0056
Schistosoma mansoni histone-lysine n-methyltransferase setb1 0.0031 0.0087 0.0085
Mycobacterium leprae PROBABLE BACTERIOFERRITIN BFRA 0.0017 0.0017 0.0275
Leishmania major cathepsin L-like protease 0.0017 0.0018 0.0128
Mycobacterium tuberculosis Probable reductase 0.0079 0.0319 0.0312
Brugia malayi hypothetical protein 0.0301 0.1399 0.6305
Leishmania major glucose transporter, lmgt3 0.0026 0.0063 0.0459
Echinococcus granulosus tm gpcr rhodopsin 0.0053 0.0193 0.0193
Brugia malayi Intermediate filament tail domain containing protein 0.0025 0.0056 0.025
Echinococcus granulosus dna polymerase eta 0.0062 0.0236 0.0236
Loa Loa (eye worm) hypothetical protein 0.016 0.0711 0.0711
Plasmodium falciparum ataxin-2 like protein, putative 0.0025 0.0057 0.0302
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0017 0.0018 0.0079
Schistosoma mansoni flap endonuclease-1 0.0023 0.0049 0.0047
Trichomonas vaginalis Clan CA, family C19, ubiquitin hydrolase-like cysteine peptidase 0.0036 0.0113 0.051
Loa Loa (eye worm) hypothetical protein 0.0246 0.1128 0.1128
Echinococcus granulosus histone acetyltransferase MYST2 0.0053 0.0192 0.0192
Brugia malayi Cathepsin L-like precursor 0.0017 0.0018 0.0077
Treponema pallidum fructose-bisphosphate aldolase 0.0287 0.1331 1
Echinococcus granulosus phd:f box containing protein 0.0015 0.0011 0.0011
Onchocerca volvulus 0.0053 0.0193 0.1348
Entamoeba histolytica protein kinase, putative 0.0026 0.0062 0.0061
Echinococcus granulosus guanine nucleotide binding protein Gs subunit 0.0045 0.0156 0.0156
Echinococcus multilocularis dna polymerase eta 0.0062 0.0236 0.0236
Loa Loa (eye worm) hypothetical protein 0.0053 0.0193 0.0193
Schistosoma mansoni hypothetical protein 0.0081 0.0329 0.0327
Mycobacterium ulcerans hypothetical protein 0.0156 0.0695 0.068
Schistosoma mansoni chromodomain helicase DNA binding protein 0.0014 0.0003 0.0001
Echinococcus granulosus neuropeptide Y receptor 0.0053 0.0193 0.0193
Brugia malayi F/Y-rich N-terminus family protein 0.0018 0.0025 0.011
Trypanosoma brucei calcium/calmodulin-dependent protein kinase, putative 0.0026 0.0062 0.0442
Echinococcus granulosus histone lysine N methyltransferase MLL3 0.0018 0.0026 0.0026
Schistosoma mansoni biogenic amine (5HT) receptor 0.0053 0.0193 0.0192
Brugia malayi Cam kinase protein 1 0.0026 0.0062 0.0275
Echinococcus multilocularis solute carrier family 2 facilitated glucose 0.0084 0.0345 0.0345
Brugia malayi Serotonin/octopamine receptor family protein 7 0.0053 0.0193 0.0869
Onchocerca volvulus 0.0015 0.0008 0.0056
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0017 0.0018 0.0079
Loa Loa (eye worm) hypothetical protein 0.0053 0.0193 0.0193
Echinococcus granulosus cathepsin L cysteine proteinase 0.0017 0.0018 0.0018
Loa Loa (eye worm) jmjC domain-containing protein 0.0015 0.0011 0.0011
Brugia malayi neuropeptide F receptor 0.0053 0.0193 0.0869
Echinococcus granulosus fmrfamide receptor 0.0053 0.0193 0.0193
Schistosoma mansoni alpha glucosidase 0.0036 0.0109 0.0108
Trypanosoma cruzi cysteine peptidase, putative 0.0064 0.0245 0.1781
Echinococcus granulosus single minded 2 0.004 0.0132 0.0132
Loa Loa (eye worm) hypothetical protein 0.0086 0.0353 0.0353
Brugia malayi jmjC domain containing protein 0.006 0.0229 0.1031
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0053 0.0193 0.0192
Trypanosoma cruzi JmjC domain, hydroxylase, putative 0.0015 0.0011 0.0076
Schistosoma mansoni phosphatidylserine receptor 0.0015 0.0011 0.0009
Schistosoma mansoni hypothetical protein 0.0291 0.1349 0.1348
Trypanosoma cruzi hexose transporter, putative 0.0026 0.0063 0.0459
Trypanosoma cruzi cysteine peptidase, putative 0.0017 0.0018 0.0128
Brugia malayi jmjC domain containing protein 0.0015 0.0011 0.0045
Entamoeba histolytica protein kinase, putative 0.0026 0.0062 0.0061
Loa Loa (eye worm) Papain cysteine protease/cathepsin propeptide inhibitor-containing protein 0.0017 0.0018 0.0018
Loa Loa (eye worm) ImpB/MucB/SamB family protein 0.0037 0.0114 0.0114
Leishmania major cathepsin L-like protease 0.0017 0.0018 0.0128
Echinococcus granulosus neuropeptide FF receptor 2 0.0053 0.0193 0.0193
Trichomonas vaginalis chromodomain-helicase-DNA-binding protein, putative 0.0023 0.0049 0.022
Brugia malayi hypothetical protein 0.0016 0.0014 0.0061
Schistosoma mansoni growth hormone secretagogue receptor 0.0053 0.0193 0.0192
Plasmodium falciparum diacylglycerol kinase, putative 0.0081 0.0329 0.1936
Loa Loa (eye worm) hypothetical protein 0.0053 0.0193 0.0193
Loa Loa (eye worm) histone methyltransferase 0.0018 0.0026 0.0026
Onchocerca volvulus 0.0016 0.0013 0.0094
Leishmania major cytochrome p450-like protein 0.002 0.0034 0.0245
Brugia malayi Unidentified vitellogenin-linked transcript protein 6, putative 0.0053 0.0193 0.0869
Echinococcus multilocularis microtubule associated protein 2 0.0688 0.3275 0.3275
Echinococcus multilocularis neuropeptide Y receptor 0.0053 0.0193 0.0193
Echinococcus multilocularis solute carrier family 2, facilitated glucose 0.0084 0.0345 0.0345
Brugia malayi Dopamine receptor protein 1, putative (partial) 0.0053 0.0193 0.0869
Trichomonas vaginalis maltase-glucoamylase, putative 0.0036 0.0109 0.0492
Schistosoma mansoni hypothetical protein 0.0015 0.0009 0.0007
Schistosoma mansoni ferritin 0.0017 0.0017 0.0015
Echinococcus granulosus solute carrier family 2 facilitated glucose 0.0084 0.0345 0.0345
Loa Loa (eye worm) hypothetical protein 0.0053 0.0193 0.0193
Echinococcus multilocularis ferritin 0.0017 0.0017 0.0017
Echinococcus granulosus neuropeptides capa receptor 0.0053 0.0193 0.0193
Trypanosoma brucei glucose transporter, putative 0.0026 0.0063 0.0453
Loa Loa (eye worm) hypothetical protein 0.0051 0.0185 0.0185
Loa Loa (eye worm) inositol-1 0.0038 0.0122 0.0122
Echinococcus multilocularis neuropeptide receptor A26 0.0473 0.2231 0.2231
Schistosoma mansoni neuropeptide receptor 0.0053 0.0193 0.0192
Schistosoma mansoni biogenic amine (dopamine) receptor 0.0053 0.0193 0.0192
Schistosoma mansoni cpg binding protein 0.0059 0.0224 0.0223
Schistosoma mansoni amine GPCR 0.0053 0.0193 0.0192
Schistosoma mansoni hypothetical protein 0.0114 0.0488 0.0486
Trypanosoma brucei PAB1-binding protein , putative 0.0025 0.0057 0.0407
Echinococcus multilocularis Ankyrin repeat domain containing protein 0.0082 0.0335 0.0335
Brugia malayi putative neuropeptide receptor 0.0053 0.0193 0.0869
Schistosoma mansoni hypothetical protein 0.0799 0.3815 0.3814
Mycobacterium ulcerans exodeoxyribonuclease III protein XthA 0.0017 0.002 0.0003
Mycobacterium tuberculosis Probable fructose-bisphosphate aldolase Fba 0.014 0.0618 0.0611
Onchocerca volvulus Cathepsin F homolog 0.0017 0.0018 0.0123
Trypanosoma cruzi DNA polymerase kappa, putative 0.0037 0.0114 0.0829
Schistosoma mansoni smad1 5 8 and 0.0022 0.0043 0.0042
Echinococcus multilocularis short transient receptor potential channel 6 0.0059 0.0225 0.0225
Onchocerca volvulus 0.0025 0.0056 0.0391
Schistosoma mansoni amine GPCR 0.0053 0.0193 0.0192
Loa Loa (eye worm) jmjC domain-containing protein 0.0015 0.0011 0.0011
Trichomonas vaginalis alpha-glucosidase, putative 0.0036 0.0109 0.0492
Trichomonas vaginalis glucose transporter, putative 0.0026 0.0063 0.0285
Loa Loa (eye worm) immunoglobulin I-set domain-containing protein 0.0015 0.0009 0.0009
Echinococcus multilocularis lysosomal alpha glucosidase 0.016 0.0714 0.0714
Echinococcus multilocularis flap endonuclease 1 0.0026 0.0061 0.0061
Schistosoma mansoni diacylglycerol kinase theta 0.0081 0.0329 0.0327
Trichomonas vaginalis glucosylceramidase, putative 0.0309 0.1433 0.6463
Loa Loa (eye worm) hypothetical protein 0.0015 0.0009 0.0009
Trypanosoma cruzi cytochrome P450, putative 0.002 0.0034 0.0245
Brugia malayi Eye-specific diacylglycerol kinase 0.0081 0.0329 0.1479
Schistosoma mansoni hypothetical protein 0.0114 0.0488 0.0486
Schistosoma mansoni jumonji domain containing protein 0.0015 0.0011 0.0009
Echinococcus granulosus terminal deoxycytidyl transferase rev1 0.0037 0.0114 0.0114
Mycobacterium tuberculosis Lysyl-tRNA synthetase 1 LysS (lysine--tRNA ligase 1) (LysRS 1) (lysine translase) 0.0016 0.0014 0.0007
Loa Loa (eye worm) hypothetical protein 0.0053 0.0193 0.0193
Schistosoma mansoni adenoreceptor 0.0053 0.0193 0.0192
Toxoplasma gondii calcium-dependent protein kinase CDPK2A 0.0026 0.0062 0.0508
Brugia malayi Probable ATP-dependent helicase DHX35 0.016 0.0711 0.3204
Brugia malayi Glycosyl hydrolases family 31 protein 0.0013 0.0001 0.0001
Loa Loa (eye worm) hypothetical protein 0.0037 0.0118 0.0118
Trypanosoma cruzi STE group serine/threonine-protein kinase, putative 0.0015 0.0008 0.0057
Giardia lamblia DINP protein human, muc B family 0.0037 0.0114 0.0719
Loa Loa (eye worm) cysteine protease 0.0017 0.0018 0.0018
Mycobacterium tuberculosis Probable bacterioferritin BfrA 0.0017 0.0017 0.001
Trypanosoma cruzi prolyl-tRNA synthetase, putative 0.0029 0.0079 0.0577
Brugia malayi Cathepsin L-like precursor 0.0017 0.0018 0.0077
Trypanosoma brucei DNA polymerase kappa, putative 0.0037 0.0114 0.0823
Loa Loa (eye worm) hypothetical protein 0.0081 0.0329 0.0329
Brugia malayi MH1 domain containing protein 0.0022 0.0043 0.0193
Loa Loa (eye worm) hypothetical protein 0.0053 0.0193 0.0193
Toxoplasma gondii LsmAD domain-containing protein 0.0025 0.0057 0.0464
Schistosoma mansoni hypothetical protein 0.0246 0.1128 0.1126
Echinococcus multilocularis nuclear factor of activated T cells 5 0.0076 0.0306 0.0306
Loa Loa (eye worm) TK/ALK protein kinase 0.0016 0.0013 0.0013
Echinococcus granulosus neutral alpha glucosidase AB 0.0036 0.0109 0.0109
Loa Loa (eye worm) hypothetical protein 0.0031 0.0087 0.0087
Leishmania major cathepsin L-like protease 0.0064 0.0245 0.1781
Trypanosoma cruzi apurinic/apyrimidinic endonuclease 0.0017 0.002 0.0145
Schistosoma mansoni amine GPCR 0.0053 0.0193 0.0192
Trichomonas vaginalis glucose transporter, putative 0.0026 0.0063 0.0285
Brugia malayi lysyl-tRNA synthetase 0.0019 0.0028 0.0122
Schistosoma mansoni histone-lysine n-methyltransferase suv9 0.0041 0.0138 0.0136
Trypanosoma brucei THT1 - hexose transporter, putative 0.0026 0.0063 0.0453
Schistosoma mansoni myelin transcription factor 1 myt1 0.0053 0.0192 0.0191
Loa Loa (eye worm) hypothetical protein 0.0053 0.0193 0.0193
Loa Loa (eye worm) gonadotropin-releasing hormone receptor 2 0.0053 0.0193 0.0193
Echinococcus multilocularis isocitrate dehydrogenase 2 (NADP+) 0.0014 0.0007 0.0007
Echinococcus multilocularis Jumonji, AT rich interactive domain 1B 0.0018 0.0026 0.0026
Schistosoma mansoni cpg binding protein 0.0059 0.0224 0.0223
Schistosoma mansoni diacylglycerol kinase theta 0.0081 0.0329 0.0327
Echinococcus granulosus lysosomal alpha glucosidase 0.016 0.0714 0.0714
Loa Loa (eye worm) CAMK/CAMK2 protein kinase 0.0026 0.0062 0.0062
Trichomonas vaginalis conserved hypothetical protein 0.0017 0.002 0.0091
Brugia malayi C2-HC type zinc finger protein C.e-MyT1 0.0053 0.0192 0.0865
Plasmodium falciparum LCCL domain-containing protein 0.002 0.0035 0.0173
Echinococcus granulosus g protein coupled receptor 0.0053 0.0193 0.0193
Loa Loa (eye worm) transcription factor SMAD2 0.0323 0.1503 0.1503
Echinococcus multilocularis tm gpcr rhodopsin gpcr rhodopsin superfamily 0.0053 0.0193 0.0193
Schistosoma mansoni NADP-specific isocitrate dehydrogenase 0.0014 0.0007 0.0005
Trichomonas vaginalis chromodomain helicase DNA binding protein, putative 0.0023 0.0049 0.022
Brugia malayi putative neuropeptide receptor NPR1 0.0053 0.0193 0.0869
Trypanosoma cruzi hypothetical protein, conserved 0.0036 0.0109 0.0792
Echinococcus multilocularis expressed protein 0.0017 0.0017 0.0017
Trypanosoma cruzi mitochondrial DNA polymerase beta-PAK, putative 0.0042 0.0139 0.1011
Echinococcus granulosus suppression of tumorigenicity 18 protein 0.0053 0.0192 0.0192
Toxoplasma gondii thioredoxin reductase 0.0035 0.0104 0.0901
Echinococcus multilocularis ankyrin repeat and death domain containing protein 0.0015 0.0009 0.0009
Loa Loa (eye worm) hypothetical protein 0.0015 0.0011 0.0011
Onchocerca volvulus 0.0053 0.0193 0.1348
Schistosoma mansoni transcription factor btf3 0.0034 0.0103 0.0102
Loa Loa (eye worm) hypothetical protein 0.002 0.0035 0.0035
Echinococcus granulosus 7TM GPCR rhodopsin 0.0053 0.0193 0.0193
Trichomonas vaginalis myo inositol monophosphatase, putative 0.0038 0.0122 0.0549
Echinococcus multilocularis inositol monophosphatase 1 0.0038 0.0122 0.0122
Trypanosoma brucei mitochondrial DNA polymerase beta 0.0297 0.1377 1
Trichomonas vaginalis glucosylceramidase, putative 0.0309 0.1433 0.6463
Schistosoma mansoni cpg binding protein 0.0056 0.0209 0.0207
Trichomonas vaginalis neutral alpha-glucosidase ab precursor, putative 0.0036 0.0109 0.0492
Trypanosoma brucei bifunctional aminoacyl-tRNA synthetase, putative 0.0029 0.0079 0.0571
Trichomonas vaginalis glucosylceramidase, putative 0.0309 0.1433 0.6463
Leishmania major mitochondrial DNA polymerase beta 0.0297 0.1377 1
Schistosoma mansoni ferritin 0.0017 0.0017 0.0015
Echinococcus granulosus lysyl tRNA synthetase 0.0019 0.0028 0.0028
Trichomonas vaginalis set domain proteins, putative 0.0237 0.1088 0.4908
Schistosoma mansoni aryl hydrocarbon receptor 0.005 0.018 0.0179
Brugia malayi hypoxia-induced factor 1 0.0156 0.0691 0.3115
Loa Loa (eye worm) hypothetical protein 0.0359 0.1679 0.1679
Loa Loa (eye worm) hypothetical protein 0.0015 0.0011 0.0011
Loa Loa (eye worm) thioredoxin reductase 0.0035 0.0104 0.0104
Schistosoma mansoni hypothetical protein 0.0053 0.0193 0.0192
Loa Loa (eye worm) hypothetical protein 0.0053 0.0193 0.0193
Echinococcus granulosus rhodopsin orphan GPCR 0.0053 0.0193 0.0193
Brugia malayi Smad1 0.0022 0.0043 0.0193
Echinococcus multilocularis calcium:calmodulin dependent protein kinase type 0.0026 0.0062 0.0062
Schistosoma mansoni voltage-gated potassium channel 0.0045 0.0154 0.0153
Loa Loa (eye worm) neuropeptide F receptor 0.0053 0.0193 0.0193
Schistosoma mansoni Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) 0.0045 0.0156 0.0154
Schistosoma mansoni cellular tumor antigen P53 0.0051 0.0185 0.0183
Trichomonas vaginalis voltage and ligand gated potassium channel, putative 0.0031 0.0089 0.0403
Schistosoma mansoni ferritin light chain 0.0017 0.0017 0.0015
Loa Loa (eye worm) hypothetical protein 0.0053 0.0193 0.0193
Schistosoma mansoni survival motor neuron protein 0.0043 0.0147 0.0145
Plasmodium falciparum calcium-dependent protein kinase 3 0.0026 0.0062 0.0331
Schistosoma mansoni glucose transport protein 0.0084 0.0345 0.0343
Trypanosoma brucei DNA polymerase IV, putative 0.0037 0.0114 0.0823
Trichomonas vaginalis ap endonuclease, putative 0.0017 0.002 0.009
Echinococcus granulosus hyperpolarization activated cyclic 0.0015 0.0008 0.0008
Brugia malayi Calcium/calmodulin-dependent protein kinase type II alpha chain 0.0026 0.0062 0.0275
Loa Loa (eye worm) hypothetical protein 0.0015 0.0011 0.0011
Entamoeba histolytica myo-inositol monophosphatase, putative 0.0038 0.0122 0.0121
Trichomonas vaginalis chromodomain helicase DNA binding protein, putative 0.0023 0.0049 0.022
Echinococcus granulosus flap endonuclease 1 0.0026 0.0061 0.0061
Loa Loa (eye worm) isocitrate dehydrogenase 0.0014 0.0007 0.0007
Schistosoma mansoni neuropeptide F-like receptor 0.0053 0.0193 0.0192
Echinococcus multilocularis dnaJ subfamily B 0.0799 0.3815 0.3815
Trypanosoma brucei DNA polymerase kappa, putative 0.0037 0.0114 0.0823
Echinococcus multilocularis acylglycerol kinase, mitochondrial 0.0081 0.0329 0.0329
Trichomonas vaginalis voltage and ligand gated potassium channel, putative 0.0015 0.0008 0.0037
Trypanosoma brucei DNA polymerase kappa, putative 0.0037 0.0114 0.0823
Mycobacterium leprae Probable fructose bisphosphate aldolase Fba 0.014 0.0618 1
Echinococcus granulosus cyclic nucleotide gated cation channel 0.0015 0.0008 0.0008
Echinococcus granulosus rhodopsin orphan GPCR 0.0053 0.0193 0.0193
Trypanosoma brucei mitochondrial DNA polymerase beta-PAK 0.0141 0.0618 0.4487
Onchocerca volvulus 0.0015 0.0008 0.0056
Echinococcus multilocularis histone acetyltransferase MYST2 0.0053 0.0192 0.0192
Brugia malayi AKH receptor 0.0053 0.0193 0.0869
Plasmodium falciparum protein kinase 6 0.0357 0.1669 1
Onchocerca volvulus 0.0017 0.0018 0.0123
Echinococcus multilocularis g protein coupled receptor 0.0053 0.0193 0.0193
Schistosoma mansoni hyperpolarization activated cyclic nucleotide-gated potassium channel 0.0015 0.0008 0.0007
Brugia malayi Flap endonuclease-1 0.0026 0.0061 0.0272
Echinococcus granulosus TRP transient receptor potential channel 0.0037 0.0115 0.0115
Schistosoma mansoni peptide (FMRFamide/somatostatin)-like receptor 0.0053 0.0193 0.0192
Echinococcus multilocularis endonuclease exonuclease phosphatase 0.0186 0.0839 0.0839
Loa Loa (eye worm) hypothetical protein 0.0053 0.0193 0.0193
Trichomonas vaginalis sugar transporter, putative 0.0026 0.0063 0.0285
Loa Loa (eye worm) hypothetical protein 0.0053 0.0193 0.0193
Brugia malayi diacylglycerol kinase 0.0081 0.0329 0.1479
Trichomonas vaginalis prolyl-tRNA synthetase, putative 0.0025 0.0059 0.0267
Trypanosoma cruzi PAB1-binding protein , putative 0.0025 0.0057 0.0413
Echinococcus multilocularis musashi 0.0025 0.0056 0.0056
Trichomonas vaginalis sphingosine kinase, putative 0.0081 0.0329 0.1482
Trypanosoma cruzi trypanothione reductase, putative 0.0035 0.0104 0.0757
Toxoplasma gondii exonuclease III APE 0.0017 0.002 0.0123
Brugia malayi hypothetical protein 0.0053 0.0193 0.0869
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0017 0.0018 0.0079
Plasmodium falciparum basic transcription factor 3b, putative 0.0034 0.0103 0.0582
Leishmania major DNA polymerase kappa, putative,DNA polymerase IV, putative 0.0037 0.0114 0.0829
Brugia malayi Tachykinin-like peptides receptor 99D 0.0053 0.0193 0.0869
Echinococcus granulosus ceramide kinase 0.0081 0.0329 0.0329
Trypanosoma brucei lysyl-tRNA synthetase, putative 0.0019 0.0028 0.0195
Echinococcus granulosus calcium:calmodulin dependent protein kinase type 0.0026 0.0062 0.0062
Onchocerca volvulus 0.0053 0.0193 0.1348
Echinococcus multilocularis potassium voltage gated channel subfamily H 0.0018 0.0023 0.0023
Entamoeba histolytica cysteine proteinase, putative 0.0017 0.0018 0.0017
Trypanosoma brucei Diacylglycerol kinase catalytic domain containing protein, putative 0.0081 0.0329 0.2381
Echinococcus multilocularis 7TM GPCR, rhodopsin 0.0053 0.0193 0.0193
Brugia malayi bifunctional aminoacyl-tRNA synthetase 0.0025 0.0059 0.0264
Echinococcus granulosus Smad4 0.0022 0.0043 0.0043
Echinococcus granulosus calcium:calmodulin dependent protein kinase type 1 0.0026 0.0062 0.0062
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0064 0.0245 0.1776
Leishmania major cathepsin L-like protease 0.0017 0.0018 0.0128
Onchocerca volvulus 0.0046 0.0161 0.1126
Plasmodium vivax SET domain protein, putative 0.0031 0.0087 0.0483
Schistosoma mansoni glucose transport protein 0.0084 0.0345 0.0343
Echinococcus multilocularis g-protein coupled receptor 0.0053 0.0193 0.0193
Echinococcus granulosus allatostatin A receptor 0.0053 0.0193 0.0193
Schistosoma mansoni peptide (FMRFamide/neurokinin-3)-like receptor 0.0053 0.0193 0.0192
Trypanosoma brucei glucose transporter, putative 0.0026 0.0063 0.0453
Schistosoma mansoni Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) 0.0045 0.0156 0.0154
Mycobacterium ulcerans DNA polymerase IV 0.0037 0.0114 0.0097
Brugia malayi MH2 domain containing protein 0.0323 0.1503 0.6774
Echinococcus multilocularis RUN 0.002 0.0035 0.0035
Echinococcus multilocularis Diacylglycerol kinase zeta 0.0081 0.0329 0.0329
Echinococcus granulosus lysine specific demethylase 6a 0.0015 0.0011 0.0011
Schistosoma mansoni hypothetical protein 0.0053 0.0193 0.0192
Schistosoma mansoni terminal deoxycytidyl transferase 0.0037 0.0114 0.0113
Plasmodium vivax mitogen-activated protein kinase 2, putative 0.0136 0.0596 0.3547
Mycobacterium tuberculosis Possible DNA-damage-inducible protein P DinP (DNA polymerase V) (pol IV 2) (DNA nucleotidyltransferase (DNA-directed)) 0.0037 0.0114 0.0108
Onchocerca volvulus 0.002 0.0035 0.0247
Echinococcus granulosus tachykinin peptides receptor 99D 0.0053 0.0193 0.0193
Brugia malayi Iron-sulfur cluster assembly accessory protein 0.0043 0.0147 0.0658
Echinococcus granulosus g protein coupled receptor 0.0053 0.0193 0.0193
Entamoeba histolytica prolyl-tRNA synthetase, putative 0.0025 0.0059 0.0058
Trypanosoma cruzi ubiquitin carboxyl-terminal hydrolase, putative 0.0036 0.0113 0.0821
Trichomonas vaginalis Clan CA, family C1, papain-like cysteine peptidase 0.0017 0.0018 0.0079
Echinococcus multilocularis sphingosine kinase 1 0.2074 1 1
Loa Loa (eye worm) 5-hydroxytryptamine 2C receptor 0.0053 0.0193 0.0193
Schistosoma mansoni hypothetical protein 0.0114 0.0488 0.0486
Brugia malayi larval opioid receptor 0.0053 0.0193 0.0869
Echinococcus granulosus thioredoxin glutathione reductase 0.0035 0.0106 0.0106
Loa Loa (eye worm) hypothetical protein 0.0053 0.0193 0.0193
Loa Loa (eye worm) hypothetical protein 0.0053 0.0193 0.0193
Trypanosoma cruzi DNA polymerase beta thumb, putative 0.0042 0.0139 0.1011
Echinococcus multilocularis guanine nucleotide binding protein G(s) subunit 0.0045 0.0156 0.0156
Schistosoma mansoni jumonji domain containing protein 0.0057 0.0214 0.0212
Onchocerca volvulus 0.0053 0.0193 0.1348
Echinococcus granulosus Diacylglycerol kinase theta 0.0081 0.0329 0.0329
Brugia malayi Immunoglobulin I-set domain containing protein 0.0015 0.0009 0.0036
Echinococcus multilocularis histone lysine N methyltransferase MLL3 0.0018 0.0026 0.0026
Trypanosoma brucei DNA polymerase IV, putative 0.0037 0.0114 0.0823
Trichomonas vaginalis chromodomain helicase DNA binding protein, putative 0.0023 0.0049 0.022
Trichomonas vaginalis voltage and ligand gated potassium channel, putative 0.0015 0.0008 0.0037
Trichomonas vaginalis neutral alpha-glucosidase ab precursor, putative 0.0013 0.0001 0.0004
Plasmodium falciparum cysteine proteinase falcipain 2b 0.0017 0.0018 0.0066
Schistosoma mansoni ferritin 0.0017 0.0017 0.0015
Onchocerca volvulus 0.0017 0.0018 0.0123
Echinococcus multilocularis rhodopsin orphan GPCR 0.0053 0.0193 0.0193
Echinococcus granulosus neuropeptide receptor 0.0053 0.0193 0.0193
Schistosoma mansoni lysyl-tRNA synthetase 0.0019 0.0028 0.0026
Schistosoma mansoni lysyl-tRNA synthetase 0.0019 0.0028 0.0026
Schistosoma mansoni multiple ankyrin repeats single kh domain protein 0.0082 0.0335 0.0333
Leishmania major glucose transporter, lmgt2 0.0026 0.0063 0.0459
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0064 0.0245 0.1776
Echinococcus multilocularis suppression of tumorigenicity 18 protein 0.0053 0.0192 0.0192
Onchocerca volvulus 0.0092 0.0385 0.2688
Trypanosoma brucei glucose transporter, putative 0.0026 0.0063 0.0453
Trichomonas vaginalis DNA polymerase IV / kappa, putative 0.0037 0.0114 0.0515
Echinococcus granulosus potassium voltage gated channel subfamily H 0.0042 0.0139 0.0139
Schistosoma mansoni Smad4 0.0022 0.0043 0.0042
Schistosoma mansoni alpha-1 adrenergic receptor 0.0053 0.0193 0.0192
Trichomonas vaginalis chromodomain helicase DNA binding protein, putative 0.0023 0.0049 0.022
Brugia malayi Pre-SET motif family protein 0.0031 0.0087 0.0389
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0017 0.0018 0.0079
Trypanosoma brucei DNA polymerase kappa, putative 0.0037 0.0114 0.0823
Echinococcus multilocularis cysteine protease 0.0017 0.0018 0.0018
Echinococcus multilocularis neuropeptide FF receptor 2 0.0053 0.0193 0.0193
Trichomonas vaginalis conserved hypothetical protein 0.0084 0.0345 0.1555
Schistosoma mansoni protein phosphatase 2C 0.0015 0.0011 0.0009
Loa Loa (eye worm) hypothetical protein 0.0053 0.0193 0.0193
Echinococcus granulosus g-protein coupled receptor 0.0053 0.0193 0.0193
Brugia malayi hypothetical protein 0.0053 0.0193 0.0869
Schistosoma mansoni smad 0.0022 0.0043 0.0042
Loa Loa (eye worm) hypothetical protein 0.0017 0.0018 0.0018
Echinococcus granulosus alpha 1A adrenergic receptor 0.0053 0.0193 0.0193
Loa Loa (eye worm) ICD-1 protein 0.0034 0.0103 0.0103
Trypanosoma cruzi myo-inositol-1(or 4)-monophosphatase 1, putative 0.0038 0.0122 0.0884
Loa Loa (eye worm) hypothetical protein 0.0053 0.0193 0.0193
Brugia malayi follicle stimulating hormone receptor 0.0053 0.0193 0.0869
Entamoeba histolytica diacylglycerol kinase, putative 0.0081 0.0329 0.0328
Brugia malayi Cathepsin L-like precursor 0.0017 0.0018 0.0077
Trichomonas vaginalis bmru protein, putative 0.0081 0.0329 0.1482
Schistosoma mansoni histone-lysine n-methyltransferase setb1 0.0031 0.0087 0.0085
Echinococcus granulosus cpg binding protein 0.0059 0.0224 0.0224
Schistosoma mansoni histamine h1 receptor 0.0053 0.0193 0.0192
Mycobacterium tuberculosis Lysyl-tRNA synthetase 2 LysX 0.0016 0.0014 0.0007
Trypanosoma cruzi ubiquitin carboxyl-terminal hydrolase, putative 0.0036 0.0113 0.0821
Echinococcus granulosus tm gpcr rhodopsin 0.0053 0.0193 0.0193
Loa Loa (eye worm) hypothetical protein 0.0053 0.0193 0.0193
Brugia malayi hypothetical protein 0.0053 0.0193 0.0869
Echinococcus granulosus geminin 0.0291 0.1349 0.1349
Trypanosoma brucei DNA polymerase kappa, putative 0.0025 0.0059 0.0423
Brugia malayi intermediate filament protein 0.0025 0.0056 0.025
Trichomonas vaginalis DNA polymerase eta, putative 0.0037 0.0114 0.0515
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0064 0.0245 0.1776
Leishmania major cathepsin L-like protease 0.0017 0.0018 0.0128
Loa Loa (eye worm) hypothetical protein 0.0301 0.1399 0.1399
Echinococcus multilocularis Smad4 0.0022 0.0043 0.0043
Loa Loa (eye worm) hypothetical protein 0.0053 0.0193 0.0193
Echinococcus granulosus sex peptide receptor 0.0053 0.0193 0.0193
Brugia malayi MH2 domain containing protein 0.0022 0.0043 0.0193
Brugia malayi hypothetical protein 0.0053 0.0193 0.0869
Echinococcus granulosus potassium voltage gated channel subfamily H 0.0018 0.0023 0.0023
Trypanosoma cruzi apurinic/apyrimidinic endonuclease, putative 0.0017 0.002 0.0145
Schistosoma mansoni loxhd1 0.002 0.0035 0.0034
Loa Loa (eye worm) unidentified vitellogenin-linked transcript protein 6 0.0053 0.0193 0.0193
Mycobacterium tuberculosis Probable exodeoxyribonuclease III protein XthA (exonuclease III) (EXO III) (AP endonuclease VI) 0.0017 0.002 0.0013
Echinococcus multilocularis peptide (allatostatin:somatostatin) 0.0053 0.0193 0.0193
Toxoplasma gondii inositol(myo)-1(or 4)-monophosphatase 2, putative 0.0038 0.0122 0.1063
Loa Loa (eye worm) glycosyl hydrolase family 31 protein 0.016 0.0714 0.0714
Brugia malayi Serotonin receptor 0.0053 0.0193 0.0869
Echinococcus multilocularis Polycystic kidney disease protein 0.002 0.0035 0.0035
Echinococcus multilocularis cadherin EGF LAG seven pass G type receptor 0.0114 0.0488 0.0488
Onchocerca volvulus 0.0301 0.1399 0.9757
Trypanosoma brucei ubiquitin carboxyl-terminal hydrolase, putative 0.0036 0.0113 0.0815
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0017 0.0018 0.0079
Echinococcus granulosus calcium:calmodulin dependent protein kinase type 0.0026 0.0062 0.0062
Onchocerca volvulus 0.0053 0.0193 0.1348
Trypanosoma cruzi glycosyl hydrolase-like protein, putative 0.0013 0.0001 0.0006
Brugia malayi hypothetical protein 0.0053 0.0193 0.0869
Trypanosoma cruzi hexose transporter, putative 0.0026 0.0063 0.0459
Onchocerca volvulus Glucosylceramidase homolog 0.0309 0.1433 1
Brugia malayi Doublecortin family protein 0.002 0.0035 0.0157
Onchocerca volvulus 0.0053 0.0193 0.1348
Trypanosoma brucei glucosidase, putative 0.0036 0.0109 0.0786
Schistosoma mansoni inositol monophosphatase 0.0038 0.0122 0.012
Loa Loa (eye worm) hypothetical protein 0.0025 0.0057 0.0057
Echinococcus multilocularis smad 0.0022 0.0043 0.0043
Echinococcus granulosus microtubule associated protein 2 0.0688 0.3275 0.3275
Loa Loa (eye worm) neuropeptide F receptor 0.0053 0.0193 0.0193
Trichomonas vaginalis CAMK family protein kinase 0.0026 0.0062 0.0278
Toxoplasma gondii prolyl-tRNA synthetase (ProRS) 0.0029 0.0079 0.0672
Entamoeba histolytica cysteine protease, putative 0.0017 0.0018 0.0017
Loa Loa (eye worm) hypothetical protein 0.0053 0.0193 0.0193
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0064 0.0245 0.1776
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0053 0.0193 0.0192
Echinococcus multilocularis alpha 1A adrenergic receptor 0.0053 0.0193 0.0193
Echinococcus granulosus calcium dependent protein kinase 0.0024 0.0054 0.0054
Brugia malayi G-protein coupled receptor 0.0053 0.0193 0.0869
Trichomonas vaginalis alpha-glucosidase, putative 0.0036 0.0109 0.0492
Brugia malayi Protein kinase domain containing protein 0.0016 0.0013 0.0058
Entamoeba histolytica diacylglycerol kinase, putative 0.0081 0.0329 0.0328
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0053 0.0193 0.0192
Schistosoma mansoni neuropeptide f receptor 76f 0.0053 0.0193 0.0192
Brugia malayi Glycosyl hydrolases family 31 protein 0.016 0.0714 0.3216
Schistosoma mansoni peptide (allatostatin/somatostatin)-like receptor 0.0053 0.0193 0.0192
Loa Loa (eye worm) MH2 domain-containing protein 0.0323 0.1503 0.1503
Trichomonas vaginalis voltage and ligand gated potassium channel, putative 0.0031 0.0089 0.0403
Loa Loa (eye worm) eye-specific diacylglycerol kinase 0.0081 0.0329 0.0329
Leishmania major hypothetical protein, conserved 0.0015 0.0011 0.0076
Loa Loa (eye worm) cyclic-nucleotide gated cation channel 0.0015 0.0008 0.0008
Trichomonas vaginalis conserved hypothetical protein 0.0081 0.0329 0.1482
Onchocerca volvulus 0.0053 0.0193 0.1348
Loa Loa (eye worm) latrophilin receptor protein 2 0.0114 0.0488 0.0488
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0017 0.0018 0.0079
Echinococcus granulosus neuropeptide s receptor 0.0473 0.2231 0.2231
Onchocerca volvulus Ceramide kinase 1 homolog 0.0081 0.0329 0.2292
Trypanosoma cruzi isocitrate dehydrogenase [NADP], mitochondrial precursor, putative 0.0014 0.0007 0.0048
Schistosoma mansoni lamin 0.0025 0.0056 0.0055
Leishmania major ubiquitin hydrolase, putative,cysteine peptidase, Clan CA, family C19, putative 0.0036 0.0113 0.0821
Brugia malayi jmjC domain containing protein 0.0015 0.0011 0.0045
Schistosoma mansoni intermediate filament proteins 0.0025 0.0056 0.0055
Schistosoma mansoni apoferritin-2 0.0017 0.0017 0.0015
Onchocerca volvulus 0.0025 0.0056 0.0391
Loa Loa (eye worm) hypothetical protein 0.0053 0.0193 0.0193
Trypanosoma brucei Sphingosine kinase 0.0081 0.0329 0.2381
Echinococcus multilocularis lysine specific demethylase 6a 0.0015 0.0011 0.0011
Trypanosoma cruzi prolyl-tRNA synthetase, putative 0.0029 0.0079 0.0577
Trichomonas vaginalis alpha-glucosidase, putative 0.0013 0.0001 0.0004
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0053 0.0193 0.0192
Loa Loa (eye worm) hypothetical protein 0.0026 0.0062 0.0062
Loa Loa (eye worm) jmjC domain-containing protein 0.006 0.0229 0.0229
Schistosoma mansoni hyperpolarization activated cyclic nucleotide-gated potassium channel 0.0015 0.0008 0.0007
Trypanosoma cruzi STE/STE11 serine/threonine-protein kinase, putative 0.0015 0.0008 0.0057
Loa Loa (eye worm) calcium/calmodulin-dependent protein kinase ID 0.0026 0.0062 0.0062
Echinococcus granulosus chromodomain helicase DNA binding protein 4 0.0014 0.0003 0.0003
Trypanosoma cruzi hexose transporter, putative 0.0026 0.0063 0.0459
Chlamydia trachomatis lysine--tRNA ligase 0.0019 0.0028 1
Trichomonas vaginalis chromodomain helicase DNA binding protein, putative 0.0023 0.0049 0.022
Trichomonas vaginalis conserved hypothetical protein 0.0034 0.0103 0.0466
Loa Loa (eye worm) hypothetical protein 0.0081 0.0329 0.0329
Loa Loa (eye worm) hypothetical protein 0.0053 0.0193 0.0193
Trichomonas vaginalis fructose-bisphosphate aldolase, putative 0.0287 0.1331 0.6
Trypanosoma brucei DNA polymerase kappa, putative 0.0037 0.0114 0.0823
Echinococcus granulosus solute carrier family 2 facilitated glucose 0.0084 0.0345 0.0345
Trichomonas vaginalis sugar transporter, putative 0.0026 0.0063 0.0285
Schistosoma mansoni glutamyl-tRNA synthetase cytoplasmic (glutamate--tRNA ligase) (glurs) 0.0025 0.0059 0.0058
Echinococcus granulosus smad 0.0022 0.0043 0.0043
Mycobacterium tuberculosis Probable dehydrogenase 0.0079 0.0319 0.0312
Loa Loa (eye worm) hypothetical protein 0.0053 0.0193 0.0193
Plasmodium vivax JmjC domain containing protein 0.0015 0.0011 0.0023
Schistosoma mansoni transient receptor potential channel 0.0059 0.0225 0.0223
Schistosoma mansoni jumonji/arid domain-containing protein 0.006 0.0229 0.0228
Plasmodium falciparum mitogen-activated protein kinase 2 0.0136 0.0596 0.3547
Schistosoma mansoni voltage-gated potassium channel 0.0045 0.0154 0.0153
Trichomonas vaginalis fructose-bisphosphate aldolase, putative 0.0287 0.1331 0.6
Mycobacterium tuberculosis Conserved hypothetical protein 0.0156 0.0695 0.0689
Echinococcus multilocularis tm gpcr rhodopsin gpcr rhodopsin superfamily 0.0053 0.0193 0.0193
Trichomonas vaginalis ferritin, putative 0.0017 0.0017 0.0077
Schistosoma mansoni DNA polymerase eta 0.0062 0.0236 0.0234
Loa Loa (eye worm) hypothetical protein 0.0053 0.0193 0.0193
Plasmodium falciparum calcium-dependent protein kinase 1 0.0026 0.0062 0.0331
Plasmodium vivax diacylglycerol kinase, putative 0.0081 0.0329 0.1936
Trichomonas vaginalis glucosylceramidase, putative 0.047 0.2218 1
Plasmodium vivax ataxin-2 like protein, putative 0.0025 0.0057 0.0302
Loa Loa (eye worm) hypothetical protein 0.002 0.0035 0.0035
Trichomonas vaginalis glucosylceramidase, putative 0.0309 0.1433 0.6463
Trichomonas vaginalis fructose-bisphosphate aldolase, putative 0.0287 0.1331 0.6
Brugia malayi hypothetical protein 0.0053 0.0193 0.0869
Schistosoma mansoni rab geranylgeranyl transferase alpha subunit 0.0037 0.0114 0.0113
Mycobacterium ulcerans fructose-bisphosphate aldolase 0.014 0.0618 0.0602
Trichomonas vaginalis Clan CA, family C1, cathepsin L or K-like cysteine peptidase 0.0017 0.0018 0.0079
Brugia malayi beta-NAC-like protein 0.0034 0.0103 0.0463
Echinococcus multilocularis tm gpcr rhodopsin gpcr rhodopsin superfamily 0.0053 0.0193 0.0193
Plasmodium falciparum lysine--tRNA ligase 0.0019 0.0028 0.0127
Mycobacterium tuberculosis NAD(P)H quinone reductase LpdA 0.0088 0.0362 0.0355
Echinococcus multilocularis neuropeptide s receptor 0.0473 0.2231 0.2231
Echinococcus granulosus neuropeptide receptor 0.0053 0.0193 0.0193
Loa Loa (eye worm) hypothetical protein 0.0093 0.0386 0.0386
Loa Loa (eye worm) hypothetical protein 0.0053 0.0193 0.0193
Leishmania major glucose transporter/membrane transporter D2, putative 0.0026 0.0063 0.0459
Leishmania major sphingosine kinase A, B, putative 0.0081 0.0329 0.2386
Brugia malayi MH1 domain containing protein 0.0022 0.0043 0.0193
Loa Loa (eye worm) mbt repeat family protein 0.0046 0.0161 0.0161
Loa Loa (eye worm) hypothetical protein 0.0053 0.0193 0.0193
Loa Loa (eye worm) Smad1 0.0022 0.0043 0.0043
Brugia malayi G-protein-linked acetylcholine receptor protein 2, putative 0.0053 0.0193 0.0869
Mycobacterium tuberculosis Diacylglycerol kinase 0.0081 0.0329 0.0322
Trichomonas vaginalis neutral alpha-glucosidase ab precursor, putative 0.0013 0.0001 0.0004
Brugia malayi hypothetical protein 0.0053 0.0193 0.0869
Leishmania major prolyl-tRNA synthetase, putative,bifunctional aminoacyl-tRNA synthetase, putative 0.0029 0.0079 0.0577
Loa Loa (eye worm) DOMON domain-containing protein 0.0015 0.0008 0.0008
Onchocerca volvulus 0.0093 0.0386 0.2694
Brugia malayi sulfakinin receptor protein 0.0053 0.0193 0.0869
Trichomonas vaginalis myo inositol monophosphatase, putative 0.0038 0.0122 0.0549
Echinococcus multilocularis netrin receptor unc 5 0.0015 0.0009 0.0009
Echinococcus multilocularis survival motor neuron protein 1 0.0212 0.0966 0.0966
Schistosoma mansoni scm-relatedprotein containing 4 mbt domains (sfmbt) 0.0046 0.0161 0.016
Mycobacterium tuberculosis Probable nitrite reductase [NAD(P)H] large subunit [FAD flavoprotein] NirB 0.0079 0.0319 0.0312
Brugia malayi Latrophilin receptor protein 2 0.0114 0.0488 0.2198
Echinococcus multilocularis arachidonate 5 lipoxygenase 0.0122 0.0528 0.0528
Echinococcus granulosus death domain containing protein 0.0015 0.0009 0.0009
Loa Loa (eye worm) hypothetical protein 0.0053 0.0193 0.0193
Echinococcus multilocularis orexin receptor type 2 0.0053 0.0193 0.0193
Brugia malayi Transient-receptor-potential like protein 0.0037 0.0115 0.0515
Echinococcus granulosus solute carrier family 2 facilitated glucose 0.0084 0.0345 0.0345
Echinococcus multilocularis Peptidase C19, ubiquitin carboxyl terminal hydrolase 2 0.0036 0.0113 0.0113
Echinococcus multilocularis NADP dependent isocitrate dehydrogenase 0.0014 0.0007 0.0007
Echinococcus multilocularis jumonji domain containing 1A 0.0015 0.0011 0.0011
Echinococcus granulosus netrin receptor unc 5 0.0015 0.0009 0.0009
Trichomonas vaginalis Clan CA, family C19, ubiquitin hydrolase-like cysteine peptidase 0.0036 0.0113 0.051
Schistosoma mansoni inositol monophosphatase 0.0038 0.0122 0.012
Echinococcus granulosus General substrate transporter 0.0072 0.0287 0.0287
Loa Loa (eye worm) CXXC zinc finger family protein 0.0056 0.0209 0.0209
Wolbachia endosymbiont of Brugia malayi fructose-1,6-bisphosphatase 0.0038 0.0122 1
Toxoplasma gondii hypothetical protein 0.0048 0.0169 0.1498
Onchocerca volvulus Cathepsin L homolog 0.0017 0.0018 0.0123
Schistosoma mansoni biogenic amine receptor 0.0053 0.0193 0.0192
Loa Loa (eye worm) hypothetical protein 0.0169 0.0755 0.0755
Echinococcus granulosus neuropeptides capa receptor 0.0053 0.0193 0.0193
Echinococcus granulosus ubiquitin specific protease 41 0.0036 0.0113 0.0113
Loa Loa (eye worm) hypothetical protein 0.0053 0.0193 0.0193
Trypanosoma brucei DNA polymerase kappa, putative 0.0025 0.0059 0.0423
Schistosoma mansoni biogenic amine (dopamine) receptor 0.0053 0.0193 0.0192
Entamoeba histolytica fructose-1,6-bisphosphate aldolase, putative 0.0287 0.1331 0.133
Echinococcus multilocularis histone lysine N methyltransferase SETMAR 0.0031 0.0087 0.0087
Echinococcus multilocularis fmrfamide receptor 0.0053 0.0193 0.0193
Loa Loa (eye worm) hypothetical protein 0.0046 0.0161 0.0161
Brugia malayi Glycosyl hydrolases family 31 protein 0.0036 0.0109 0.0489
Echinococcus granulosus cathepsin l cysteine peptidase 0.0017 0.0018 0.0018
Echinococcus multilocularis dna polymerase kappa 0.0037 0.0114 0.0114
Echinococcus granulosus transcription factor btf3 0.0034 0.0103 0.0103
Schistosoma mansoni hypothetical protein 0.002 0.0035 0.0034
Loa Loa (eye worm) hypothetical protein 0.0053 0.0192 0.0192
Brugia malayi hypothetical protein 0.0053 0.0193 0.0869
Trichomonas vaginalis sugar transporter, putative 0.0026 0.0063 0.0285
Loa Loa (eye worm) O-glycosyl hydrolase family 30 protein 0.047 0.2218 0.2218
Echinococcus multilocularis transient receptor potential gamma protein 0.0086 0.0353 0.0353
Brugia malayi Protein kinase domain containing protein 0.0016 0.0016 0.0072
Trypanosoma brucei hypothetical protein, conserved 0.0081 0.0329 0.2381
Loa Loa (eye worm) hypothetical protein 0.0036 0.0113 0.0113
Toxoplasma gondii diacylglycerol kinase accessory domain (presumed) domain-containing protein 0.0081 0.0329 0.2972
Echinococcus multilocularis tumor protein p63 0.0349 0.163 0.163
Echinococcus granulosus cyclic nucleotide gated cation channel 0.0015 0.0008 0.0008
Echinococcus multilocularis DNA (apurinic or apyrimidinic site) lyase 0.0017 0.002 0.002
Schistosoma mansoni serine/threonine protein kinase 0.0026 0.0062 0.006
Trypanosoma cruzi STE group serine/threonine-protein kinase, putative 0.0015 0.0008 0.0057
Echinococcus granulosus G protein coupled receptor 139 0.0053 0.0193 0.0193
Loa Loa (eye worm) CYP4Cod1 0.002 0.0034 0.0034
Brugia malayi hypothetical protein 0.002 0.0035 0.0157
Echinococcus granulosus dnaJ subfamily B 0.0799 0.3815 0.3815
Echinococcus multilocularis neutral alpha glucosidase AB 0.0036 0.0109 0.0109
Echinococcus granulosus potassium:sodium hyperpolarization activated 0.0015 0.0008 0.0008
Loa Loa (eye worm) hypothetical protein 0.0016 0.0013 0.0013
Echinococcus multilocularis lipoxygenase domain containing protein 0.002 0.0035 0.0035
Trichomonas vaginalis fructose-bisphosphate aldolase, putative 0.0287 0.1331 0.6
Leishmania major hypothetical protein, conserved 0.0081 0.0329 0.2386
Brugia malayi jmjC domain containing protein 0.0015 0.0011 0.0045
Trypanosoma cruzi mitochondrial DNA polymerase beta-PAK, putative 0.0141 0.0618 0.449
Echinococcus multilocularis dro:myosuppressin receptor 0.0053 0.0193 0.0193
Trypanosoma brucei glucose transporter, putative 0.0026 0.0063 0.0453
Brugia malayi ORL1-like opioid receptor 0.0053 0.0193 0.0869
Giardia lamblia Fructose-bisphosphate aldolase 0.0287 0.1331 1
Echinococcus multilocularis neuropeptides capa receptor 0.0053 0.0193 0.0193
Trypanosoma brucei DNA polymerase kappa, putative 0.0037 0.0114 0.0823
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0053 0.0193 0.0192
Trypanosoma brucei glucose transporter, putative 0.0026 0.0063 0.0453
Onchocerca volvulus 0.0017 0.0018 0.0123
Trichomonas vaginalis chromodomain helicase DNA binding protein, putative 0.0016 0.0016 0.0071
Trichomonas vaginalis maltase-glucoamylase, putative 0.0013 0.0001 0.0004
Treponema pallidum exodeoxyribonuclease (exoA) 0.0017 0.002 0.0022
Trypanosoma cruzi DNA polymerase eta, putative 0.0062 0.0236 0.1711
Trypanosoma brucei glucose transporter, putative 0.0026 0.0063 0.0453
Mycobacterium tuberculosis Conserved hypothetical protein 0.0037 0.0114 0.0108
Echinococcus multilocularis calcium dependent protein kinase 0.0024 0.0054 0.0054
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0064 0.0245 0.1776
Loa Loa (eye worm) hypothetical protein 0.0212 0.0966 0.0966
Onchocerca volvulus 0.0043 0.0147 0.1022
Schistosoma mansoni mixed-lineage leukemia protein mll 0.012 0.0519 0.0518
Loa Loa (eye worm) hypothetical protein 0.0298 0.1383 0.1383
Echinococcus multilocularis G protein coupled receptor 139 0.0053 0.0193 0.0193
Brugia malayi PAS domain containing protein 0.005 0.018 0.0811
Schistosoma mansoni single-minded 0.005 0.018 0.0179
Loa Loa (eye worm) hypothetical protein 0.0053 0.0193 0.0193
Echinococcus multilocularis geminin 0.0291 0.1349 0.1349
Trypanosoma brucei trypanothione reductase 0.0035 0.0104 0.0751
Echinococcus multilocularis transfer RNA-Lys 0.0037 0.0117 0.0117
Schistosoma mansoni hypothetical protein 0.0053 0.0193 0.0192
Schistosoma mansoni hypothetical protein 0.0114 0.0488 0.0486
Schistosoma mansoni protein kinase 0.0026 0.0062 0.006
Schistosoma mansoni netrin receptor unc5 0.0015 0.0009 0.0007
Schistosoma mansoni opsin-like receptor 0.0053 0.0193 0.0192
Echinococcus granulosus DNA apurinic or apyrimidinic site lyase 0.0017 0.002 0.002
Echinococcus multilocularis rhodopsin orphan GPCR 0.0053 0.0193 0.0193
Trypanosoma cruzi isocitrate dehydrogenase, putative 0.0014 0.0007 0.0048
Echinococcus granulosus G protein coupled 5 hydroxytryptamine receptor 0.0053 0.0193 0.0193
Leishmania major cathepsin L-like protease 0.0064 0.0245 0.1781
Entamoeba histolytica hypothetical protein 0.0019 0.0028 0.0027
Leishmania major glucose transporter, lmgt1 0.0026 0.0063 0.0459
Toxoplasma gondii cathepsin CPL 0.0017 0.0018 0.0102
Echinococcus granulosus serotonin receptor 0.0053 0.0193 0.0193
Schistosoma mansoni ferritin 0.0017 0.0017 0.0015
Echinococcus multilocularis thioredoxin glutathione reductase 0.0035 0.0106 0.0106
Brugia malayi Thioredoxin reductase 0.0035 0.0104 0.0467
Plasmodium vivax calcium-dependent protein kinase 1, putative 0.0026 0.0062 0.0331
Brugia malayi mbt repeat family protein 0.0046 0.0161 0.0725
Trypanosoma cruzi cruzipain precursor, putative 0.0064 0.0245 0.1781
Loa Loa (eye worm) G-protein coupled receptor 0.0053 0.0193 0.0193
Trypanosoma cruzi DNA polymerase kappa, putative 0.0037 0.0114 0.0829
Trichomonas vaginalis conserved hypothetical protein 0.0034 0.0103 0.0466
Trichomonas vaginalis Clan CA, family C1, papain-like cysteine peptidase 0.0017 0.0018 0.0079
Trypanosoma cruzi cysteine peptidase, putative 0.0064 0.0245 0.1781
Echinococcus multilocularis thyrotropin releasing hormone receptor 0.0053 0.0193 0.0193
Loa Loa (eye worm) papain family cysteine protease containing protein 0.0017 0.0018 0.0018
Trypanosoma cruzi mitochondrial DNA polymerase beta, putative 0.0297 0.1377 1
Plasmodium vivax vivapain-2 0.0017 0.0018 0.0066
Echinococcus granulosus calcium:calmodulin dependent protein kinase type 0.0026 0.0062 0.0062
Loa Loa (eye worm) sugar transporter 0.0084 0.0345 0.0345
Mycobacterium leprae Probable lysyl-tRNA synthase LysS (lysine--tRNA ligase 1) (LysRS 1) (lysine translase) 0.0016 0.0014 0.0227
Echinococcus multilocularis g protein linked acetylcholine receptor gar 2a 0.0053 0.0193 0.0193
Toxoplasma gondii calcium-dependent protein kinase CDPK3 0.0026 0.0062 0.0508
Loa Loa (eye worm) hypothetical protein 0.0015 0.0008 0.0008
Echinococcus multilocularis hyperpolarization activated cyclic 0.0015 0.0008 0.0008
Mycobacterium leprae possible inositol monophosphatase SubH (IMPase) (inositol-1-phosphatase) (I-1-Pase ). 0.0034 0.0102 0.1657
Trichomonas vaginalis glucosylceramidase, putative 0.0309 0.1433 0.6463
Schistosoma mansoni voltage-gated potassium channel 0.0018 0.0023 0.0022
Echinococcus granulosus TGF beta signal transducer SmadC 0.0022 0.0043 0.0043
Leishmania major cathepsin L-like protease 0.0064 0.0245 0.1781
Echinococcus granulosus solute carrier family 2 facilitated glucose 0.0084 0.0345 0.0345
Echinococcus granulosus cadherin EGF LAG seven pass G type receptor 0.0114 0.0488 0.0488
Brugia malayi Serotonin receptor 0.0053 0.0193 0.0869
Trichomonas vaginalis fructose-bisphosphate aldolase, putative 0.0287 0.1331 0.6
Echinococcus granulosus Jumonji AT rich interactive domain 1B 0.0018 0.0026 0.0026
Entamoeba histolytica deoxycytidyl transferase, putative 0.0037 0.0114 0.0113
Echinococcus granulosus mothers against decapentaplegic 5 0.0022 0.0043 0.0043
Trypanosoma brucei apurinic/apyrimidinic endonuclease, putative 0.0017 0.002 0.0139
Loa Loa (eye worm) GTP-binding regulatory protein Gs alpha-S chain 0.0045 0.0156 0.0156
Giardia lamblia Lysyl-tRNA synthetase 0.0019 0.0028 0.006
Trypanosoma brucei DNA polymerase eta, putative 0.0062 0.0236 0.1706
Plasmodium falciparum ataxin-2 like protein, putative 0.0025 0.0057 0.0302
Echinococcus granulosus ankyrin repeat and death domain containing protein 0.0015 0.0009 0.0009
Loa Loa (eye worm) glutathione reductase 0.0035 0.0104 0.0104
Onchocerca volvulus 0.0051 0.0185 0.1287
Schistosoma mansoni sex comb on midleg homolog 0.0046 0.0161 0.016
Trypanosoma cruzi diacylglycerol kinase-like protein, putative 0.0081 0.0329 0.2386
Trypanosoma cruzi Sphingosine kinase 0.0081 0.0329 0.2386
Echinococcus granulosus voltage gated potassium channel 0.0018 0.0023 0.0023
Leishmania major diacylglycerol kinase-like protein 0.0081 0.0329 0.2386
Echinococcus granulosus cathepsin l1 0.0017 0.0018 0.0018
Brugia malayi hypothetical protein 0.0053 0.0193 0.0869
Entamoeba histolytica Flap nuclease, putative 0.0026 0.0061 0.006
Loa Loa (eye worm) hypothetical protein 0.0053 0.0193 0.0193
Schistosoma mansoni transient receptor potential channel 4 0.0086 0.0353 0.0352
Trypanosoma brucei DNA polymerase kappa, putative 0.0037 0.0114 0.0823
Loa Loa (eye worm) hypothetical protein 0.0026 0.0065 0.0065
Trypanosoma cruzi hypothetical protein, conserved 0.0036 0.0109 0.0792
Leishmania major basic transcription factor 3a, putative 0.0034 0.0103 0.0751
Echinococcus granulosus somatostatin receptor 0.0053 0.0193 0.0193
Loa Loa (eye worm) ceramide kinase 0.0081 0.0329 0.0329
Brugia malayi jmjC domain containing protein 0.0057 0.0214 0.0961
Trypanosoma brucei glucose transporter, putative 0.0026 0.0063 0.0453
Echinococcus multilocularis lysine specific demethylase 5A 0.0057 0.0214 0.0214
Echinococcus multilocularis lipoxygenase domain containing protein 0.002 0.0035 0.0035
Brugia malayi Death domain containing protein 0.0015 0.0009 0.0036
Loa Loa (eye worm) doublecortin family protein 0.002 0.0035 0.0035
Mycobacterium tuberculosis Probable NADH dehydrogenase Ndh 0.0079 0.0319 0.0312
Echinococcus multilocularis short transient receptor potential channel 6 0.0059 0.0225 0.0225
Plasmodium vivax AP endonuclease (DNA-[apurinic or apyrimidinic site] lyase), putative 0.0017 0.002 0.008
Trichomonas vaginalis alpha-glucosidase, putative 0.0013 0.0001 0.0004
Echinococcus granulosus mixed lineage leukemia protein mll 0.0015 0.001 0.001
Schistosoma mansoni sphingoid long chain base kinase 0.2074 1 1
Onchocerca volvulus 0.0017 0.0018 0.0123
Trypanosoma cruzi major cysteine proteinase, putative 0.005 0.0179 0.1301
Mycobacterium tuberculosis Dihydrolipoamide dehydrogenase LpdC (lipoamide reductase (NADH)) (lipoyl dehydrogenase) (dihydrolipoyl dehydrogenase) (diaphoras 0.0088 0.0362 0.0355
Echinococcus multilocularis allatostatin A receptor 0.0053 0.0193 0.0193
Schistosoma mansoni multiple ankyrin repeats single kh domain protein 0.0082 0.0335 0.0333
Brugia malayi Voltage-gated potassium channel, HERG (KCNH2)-related. C. elegans unc-103 ortholog 0.0042 0.0139 0.0625
Brugia malayi O-Glycosyl hydrolase family 30 protein 0.047 0.2218 1
Trichomonas vaginalis diacylglycerol kinase, zeta, iota, putative 0.0081 0.0329 0.1482
Brugia malayi GTP-binding regulatory protein Gs alpha-S chain, putative 0.0045 0.0156 0.0699
Onchocerca volvulus 0.0053 0.0193 0.1348
Onchocerca volvulus 0.0017 0.0018 0.0123
Trichomonas vaginalis chromodomain-helicase-DNA-binding protein, putative 0.0023 0.0049 0.022
Onchocerca volvulus 0.0053 0.0193 0.1348
Brugia malayi Pre-SET motif family protein 0.0209 0.0949 0.4279
Toxoplasma gondii histone lysine methyltransferase SET1 0.0107 0.0458 0.4164
Loa Loa (eye worm) hypothetical protein 0.0015 0.0008 0.0008
Trichomonas vaginalis Clan CA, family C1, papain-like cysteine peptidase 0.0017 0.0018 0.0079
Schistosoma mansoni thyrotropin-releasing hormone receptor 0.0053 0.0193 0.0192
Trypanosoma brucei transcription factor BTF3, putative 0.0034 0.0103 0.0745
Onchocerca volvulus 0.0017 0.0018 0.0123
Echinococcus granulosus survival motor neuron protein 1 0.0212 0.0966 0.0966
Echinococcus granulosus peptide allatostatin:somatostatin 0.0053 0.0193 0.0193
Brugia malayi G protein-coupled receptor 0.0053 0.0193 0.0869
Trichomonas vaginalis diacylglycerol kinase, epsilon, putative 0.0081 0.0329 0.1482
Entamoeba histolytica hypothetical protein 0.0034 0.0103 0.0103
Trypanosoma brucei unspecified product 0.0025 0.0059 0.0423
Toxoplasma gondii diacylglycerol kinase catalytic domain-containing protein 0.0081 0.0329 0.2972
Toxoplasma gondii lysine-tRNA ligase 0.0019 0.0028 0.0195
Giardia lamblia Prolyl-tRNA synthetase 0.0025 0.0059 0.0299
Echinococcus granulosus lamin 0.0025 0.0056 0.0056
Echinococcus granulosus arachidonate 5 lipoxygenase 0.0122 0.0528 0.0528
Toxoplasma gondii facilitative glucose transporter GT1 0.0084 0.0345 0.3122
Trichomonas vaginalis alpha-glucosidase, putative 0.0036 0.0109 0.0492
Trichomonas vaginalis sucrase-isomaltase, putative 0.0036 0.0109 0.0492
Plasmodium falciparum calcium-dependent protein kinase 5 0.0026 0.0062 0.0331
Loa Loa (eye worm) MBCTL1 0.0053 0.0192 0.0192
Trypanosoma brucei JmjC domain, hydroxylase, putative 0.0015 0.0011 0.007
Echinococcus multilocularis mixed lineage leukemia protein mll 0.0015 0.001 0.001
Trypanosoma cruzi mitochondrial DNA polymerase beta-PAK, putative 0.0051 0.0183 0.1332
Leishmania major protein kinase, putative 0.0019 0.0029 0.0213
Plasmodium vivax calcium-dependent protein kinase 3, putative 0.0026 0.0062 0.0331
Trypanosoma cruzi DNA polymerase beta thumb, putative 0.0042 0.0139 0.1011
Schistosoma mansoni hypothetical protein 0.0015 0.0008 0.0006
Entamoeba histolytica transcription factor BTF3, putative 0.0034 0.0103 0.0103
Trichomonas vaginalis Clan CA, family C1, papain-like cysteine peptidase 0.0017 0.0018 0.0079
Brugia malayi Sugar transporter family protein 0.0084 0.0345 0.1553
Brugia malayi hypothetical protein 0.0169 0.0755 0.3401
Brugia malayi Cathepsin L-like precursor 0.0017 0.0018 0.0077
Echinococcus granulosus lipoxygenase domain containing protein 0.002 0.0035 0.0035
Echinococcus multilocularis neuropeptide receptor 0.0053 0.0193 0.0193
Loa Loa (eye worm) pigment dispersing factor receptor c 0.0359 0.1679 0.1679
Trypanosoma cruzi glycosyl hydrolase-like protein, putative 0.0013 0.0001 0.0006
Entamoeba histolytica ubiquitin carboxyl-terminal hydrolase domain containing protein 0.0036 0.0113 0.0112
Trichomonas vaginalis glucosylceramidase, putative 0.0309 0.1433 0.6463
Plasmodium falciparum flap endonuclease 1 0.0026 0.0061 0.0326
Echinococcus multilocularis histone lysine N methyltransferase MLL3 0.0015 0.001 0.001
Loa Loa (eye worm) cytochrome P450 family protein 0.002 0.0034 0.0034
Mycobacterium ulcerans diacylglycerol kinase 0.0081 0.0329 0.0312
Echinococcus granulosus hypothetical protein 0.0053 0.0193 0.0193
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0064 0.0245 0.1776
Leishmania major mitochondrial DNA polymerase beta-PAK, putative 0.0141 0.0618 0.449
Echinococcus granulosus RUN 0.002 0.0035 0.0035
Trichomonas vaginalis inositol monophosphatase, putative 0.0038 0.0122 0.0549
Echinococcus granulosus inositol monophosphatase 1 0.0038 0.0122 0.0122
Echinococcus multilocularis calcium:calmodulin dependent protein kinase type 0.0026 0.0062 0.0062
Echinococcus multilocularis G-protein coupled receptor, putative 0.0053 0.0193 0.0193
Brugia malayi SEA domain containing protein 0.0015 0.0008 0.0033
Plasmodium falciparum cysteine proteinase falcipain 3 0.0017 0.0018 0.0066
Brugia malayi mbt repeat family protein 0.0046 0.0161 0.0725
Echinococcus granulosus ubiquitin carboxyl terminal hydrolase 8 0.0036 0.0113 0.0113
Brugia malayi G protein-coupled receptor F59B2.13 0.0053 0.0193 0.0869
Leishmania major hypothetical protein, conserved 0.0081 0.0329 0.2386
Loa Loa (eye worm) G-protein-linked acetylcholine receptor protein 2 0.0053 0.0193 0.0193
Brugia malayi Cathepsin L-like precursor 0.0017 0.0018 0.0077
Brugia malayi hypothetical protein 0.002 0.0035 0.0157
Trypanosoma cruzi transcription factor btf3, putative 0.0034 0.0103 0.0751
Onchocerca volvulus 0.0053 0.0193 0.1348
Trichomonas vaginalis Clan CA, family C1, papain-like cysteine peptidase 0.0017 0.0018 0.0079
Schistosoma mansoni biogenic amine (5HT) receptor 0.0298 0.1383 0.1382
Schistosoma mansoni apoferritin-2 0.0017 0.0017 0.0015
Plasmodium falciparum proline--tRNA ligase 0.0029 0.0079 0.0438
Echinococcus multilocularis glutamyl tRNA synthetase cytoplasmic 0.0025 0.0059 0.0059
Trypanosoma brucei DNA polymerase beta thumb, putative 0.0042 0.0139 0.1005
Schistosoma mansoni amine GPCR 0.0053 0.0193 0.0192
Loa Loa (eye worm) hypothetical protein 0.0015 0.0008 0.0008
Loa Loa (eye worm) hypothetical protein 0.0049 0.0175 0.0175
Echinococcus multilocularis diuretic hormone 44 receptor GPRdih2 0.0114 0.0488 0.0488
Echinococcus granulosus biogenic amine 5HT receptor 0.0053 0.0193 0.0193
Brugia malayi glutathione reductase 0.0035 0.0104 0.0467
Trypanosoma brucei glucose transporter 1E 0.0026 0.0063 0.0453
Echinococcus multilocularis NADP dependent isocitrate dehydrogenase 0.0014 0.0007 0.0007
Onchocerca volvulus Netrin receptor homolog 0.0015 0.0009 0.0061
Echinococcus granulosus orexin receptor type 2 0.0053 0.0193 0.0193
Trypanosoma brucei DNA polymerase kappa, putative 0.0037 0.0114 0.0823
Brugia malayi exodeoxyribonuclease III family protein 0.0017 0.002 0.0087
Trypanosoma brucei inositol-1(or 4)-monophosphatase 1, putative 0.0038 0.0122 0.0878
Leishmania major flap endonuclease-1 (FEN-1), putative 0.0026 0.0061 0.0442
Echinococcus multilocularis chromodomain helicase DNA binding protein 4 0.0014 0.0003 0.0003
Schistosoma mansoni protein kinase 0.0026 0.0062 0.006
Trypanosoma brucei unspecified product 0.0037 0.0114 0.0823
Leishmania major calcium channel protein, putative,ion transporter, putative 0.0047 0.0162 0.1179
Entamoeba histolytica fructose-1,6-bisphosphate aldolase, putative 0.0287 0.1331 0.133
Schistosoma mansoni neuropeptide receptor 0.0053 0.0193 0.0192
Echinococcus granulosus short transient receptor potential channel 6 0.0059 0.0225 0.0225
Loa Loa (eye worm) pre-SET domain-containing protein family protein 0.0209 0.0949 0.0949
Schistosoma mansoni voltage-gated potassium channel 0.0018 0.0023 0.0022
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0053 0.0193 0.0192
Echinococcus multilocularis neuropeptides capa receptor 0.0053 0.0193 0.0193
Trypanosoma brucei DNA polymerase kappa, putative 0.0037 0.0114 0.0823
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0017 0.0018 0.0079
Echinococcus granulosus dna polymerase kappa 0.0037 0.0114 0.0114
Echinococcus multilocularis voltage gated potassium channel 0.0018 0.0023 0.0023
Schistosoma mansoni hypothetical protein 0.0043 0.0147 0.0145
Echinococcus granulosus thyrotropin releasing hormone receptor 0.0053 0.0193 0.0193
Brugia malayi jmjC domain containing protein 0.0015 0.0011 0.0045
Trichomonas vaginalis conserved hypothetical protein 0.0026 0.0063 0.0285
Brugia malayi CHD4 protein 0.0014 0.0003 0.0009
Brugia malayi G-protein coupled receptor 0.0053 0.0193 0.0869
Brugia malayi hypothetical protein 0.0025 0.0057 0.0254
Plasmodium vivax flap endonuclease 1, putative 0.0026 0.0061 0.0326
Echinococcus multilocularis phd:f box containing protein 0.0015 0.0011 0.0011
Brugia malayi Ubiquitin carboxyl-terminal hydrolase family protein 0.0036 0.0113 0.0507
Echinococcus granulosus rhodopsin orphan GPCR 0.0053 0.0193 0.0193
Schistosoma mansoni cathepsin F (C01 family) 0.0017 0.0018 0.0016
Plasmodium falciparum hexose transporter 0.0084 0.0345 0.2034
Mycobacterium tuberculosis Bacterioferritin BfrB 0.0017 0.0017 0.001
Mycobacterium tuberculosis NADPH-dependent mycothiol reductase Mtr 0.0035 0.0104 0.0098
Trypanosoma cruzi hypothetical protein, conserved 0.0081 0.0329 0.2386
Echinococcus multilocularis Ankyrin 0.0015 0.0009 0.0009
Brugia malayi hypothetical protein 0.0093 0.0386 0.1738
Mycobacterium ulcerans hypothetical protein 0.2074 1 1
Trypanosoma cruzi DNA polymerase kappa, putative 0.0037 0.0114 0.0829

Activities

Activity type Activity value Assay description Source Reference
IC50 (binding) > 300 uM Displacement of biotinylated fibrinogen from human glycoprotein 2b/3a receptor after 2 hrs by chemiluminescence assay ChEMBL. 23644213
Ki (binding) = 38.2 uM Inhibition of F10a (unknown origin) using S-2222 as substrate incubated for 15 mins prior to substrate addition measured every 10 secs by spectrophotometric analysis ChEMBL. 23644213
Ki (binding) > 100 uM Inhibition of trypsin (unknown origin) using S-2222 as substrate incubated for 15 mins prior to substrate addition measured every 10 secs by spectrophotometric analysis ChEMBL. 23644213
Ki (binding) > 100 uM Inhibition of thrombin (unknown origin) using S-2238 as substrate incubated for 15 mins prior to substrate addition measured every 10 secs by spectrophotometric analysis ChEMBL. 23644213

Phenotypes

Whole-cell/tissue/organism interactions

We have no records of whole-cell/tissue assays done with this compound What does this mean?

Many chemical entities in TDR Targets come from high-throughput screenings with whole cells or tissue samples, and not all assayed compounds have been tested against a single a single target protein, probably because they get ruled out during screening process. Even if these compounds may have not been of interest in the original screening, they may come as interesting leads for other screening assays. Furthermore, we may be able to propose drug-target associations using chemical similarities and network patterns.

Annotated phenotypes:

We have no manually annotated phenotypes for this drug. What does this mean? / Care to help?
In TDR Targets, information about phenotypes that are caused by drugs, or by genetic manipulation of cells (e.g. gene knockouts or knockdowns) is manually curated from the literature. These descriptions help to describe the potential of the target for drug development. If no information is available for this gene or if the information is incomplete, this may mean that i) the papers containing this information either appeared after the curation effort for this organism was carried out or they were inadvertently missed by curators; or that ii) the curation effort for this organism has not yet started.
 
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External resources for this compound

Bibliographic References

1 literature reference was collected for this gene.

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