Detailed information for compound 178445

Basic information

Technical information
  • Name: Unnamed compound
  • MW: 370.363 | Formula: C17H18N6O4
  • H donors: 4 H acceptors: 6 LogP: -0.41 Rotable bonds: 5
    Rule of 5 violations (Lipinski): 1
  • SMILES: O=C([C@@H]1O[C@@H]([C@H]([C@@H]1O)O)n1cnc2c1ncnc2N)NCc1ccccc1
  • InChi: 1S/C17H18N6O4/c18-14-10-15(21-7-20-14)23(8-22-10)17-12(25)11(24)13(27-17)16(26)19-6-9-4-2-1-3-5-9/h1-5,7-8,11-13,17,24-25H,6H2,(H,19,26)(H2,18,20,21)/t11?,12-,13-,17+/m0/s1
  • InChiKey: VDAITUUOENAMKK-WLRYYPKHSA-N  


Substructure search Similarity search

Network

Hover on a compound node to display the structore

Synonyms

No synonyms found for this compound

Targets

Known targets for this compound

No curated genes were found associated with this compound

Predicted pathogen targets for this compound

By orthology
No druggable targets predicted by orthology data
By sequence similarity to non orthologous known druggable targets
No druggable targets predicted by sequence similarity
Obtained from network model

Ranking Plot

Putative Targets List

Species Potential target Raw Global Species
Loa Loa (eye worm) nuclear factor I 0.0034 0.0056 0.0121
Trypanosoma cruzi mitogen-activated protein kinase 11, putative 0.0058 0.0133 0.0474
Brugia malayi Glycosyl hydrolases family 31 protein 0.0139 0.039 0.0839
Trypanosoma brucei ring finger containing protein 0.0027 0.0033 0.0053
Trichomonas vaginalis conserved hypothetical protein 0.0027 0.0033 0.0071
Loa Loa (eye worm) hypothetical protein 0.0027 0.0033 0.0071
Brugia malayi Neuralized family protein 0.0027 0.0033 0.0071
Echinococcus multilocularis Nuclear hormone receptor family member nhr 41 0.0051 0.0111 0.0144
Plasmodium vivax AP endonuclease (DNA-[apurinic or apyrimidinic site] lyase), putative 0.0038 0.0069 0.0148
Loa Loa (eye worm) RiNg Finger protein family member 0.0027 0.0033 0.0072
Echinococcus granulosus 5'partial|histone lysine N methyltransferase SETDB2 0.003 0.0043 0.0055
Mycobacterium tuberculosis Probable carboxylesterase CaeA 0.0087 0.0224 0.0203
Mycobacterium ulcerans fatty-acid-CoA ligase 0.0032 0.0051 0.003
Schistosoma mansoni TGF-beta signal transducer Smad2 0.0062 0.0144 0.0158
Echinococcus granulosus TGF beta signal transducer SmadC 0.0062 0.0144 0.0186
Leishmania major hypothetical protein, conserved 0.0027 0.0033 0.0117
Trypanosoma cruzi UEV domain/Zinc finger, C3HC4 type (RING finger), putative 0.0027 0.0033 0.0117
Brugia malayi DnaJ domain containing protein 0.0071 0.0173 0.0373
Leishmania major acetoin dehydrogenase e3 component-like protein 0.0312 0.0942 0.3344
Schistosoma mansoni nuclear hormone receptor nor-1/nor-2 0.0051 0.0111 0.0122
Loa Loa (eye worm) hypothetical protein 0.0028 0.0036 0.0077
Trypanosoma cruzi Ankyrin repeats (3 copies)/Zinc finger, C3HC4 type (RING finger), putative 0.0027 0.0033 0.0117
Plasmodium falciparum dihydrolipoyl dehydrogenase, mitochondrial 0.0312 0.0942 0.2027
Echinococcus granulosus ring finger protein 170 0.0027 0.0033 0.0043
Schistosoma mansoni bromodomain-containing nuclear protein 1 brd1 0.003 0.0044 0.0048
Trichomonas vaginalis dihydrolipoamide dehydrogenase, putative 0.0083 0.0212 0.0456
Echinococcus granulosus guanine nucleotide binding protein Gs subunit 0.0126 0.0347 0.0449
Mycobacterium tuberculosis Probable chain -fatty-acid-CoA ligase FadD13 (fatty-acyl-CoA synthetase) 0.0043 0.0086 0.0065
Leishmania major hypothetical protein, conserved 0.0083 0.0212 0.0752
Leishmania major hypothetical protein, conserved 0.0525 0.1619 0.575
Schistosoma mansoni sulfide quinone reductase 0.0083 0.0212 0.0232
Onchocerca volvulus Steroid hormone receptor family member cnr14 homolog 0.0051 0.0111 0.024
Loa Loa (eye worm) hypothetical protein 0.0051 0.0111 0.024
Mycobacterium tuberculosis Possible haloalkane dehalogenase 0.0087 0.0224 0.0203
Onchocerca volvulus Bile acid receptor homolog 0.0051 0.0111 0.024
Brugia malayi MH2 domain containing protein 0.0905 0.2828 0.6086
Echinococcus multilocularis mothers against decapentaplegic 6 0.0028 0.0036 0.0046
Toxoplasma gondii alpha/beta hydrolase, putative 0.0087 0.0224 0.0482
Onchocerca volvulus RING finger protein 141 homolog 0.0027 0.0033 0.0071
Mycobacterium tuberculosis Probable pyruvate kinase PykA 0.007 0.017 0.015
Leishmania major trypanothione reductase 0.0901 0.2816 1
Loa Loa (eye worm) latrophilin receptor protein 2 0.0065 0.0153 0.033
Onchocerca volvulus Pyruvate kinase homolog 0.007 0.017 0.0367
Trichomonas vaginalis conserved hypothetical protein 0.0027 0.0033 0.0071
Brugia malayi Pyruvate kinase, muscle isozyme 0.007 0.017 0.0367
Trichomonas vaginalis 2-deoxyglucose-6-phosphate phosphatase, putative 0.0082 0.0208 0.0448
Trichomonas vaginalis 2-deoxyglucose-6-phosphate phosphatase, putative 0.0082 0.0208 0.0448
Leishmania major hypothetical protein, conserved 0.0027 0.0033 0.0117
Trichomonas vaginalis glucosylceramidase, putative 0.0177 0.051 0.1098
Echinococcus multilocularis SWI:SNF matrix associated 0.1477 0.4646 0.6003
Giardia lamblia Hypothetical protein 0.0027 0.0033 0.016
Trichomonas vaginalis 2-deoxyglucose-6-phosphate phosphatase, putative 0.0082 0.0208 0.0448
Trypanosoma cruzi dihydrolipoyl dehydrogenase, putative 0.0312 0.0942 0.3344
Plasmodium falciparum histone acetyltransferase GCN5 0.0039 0.0072 0.0155
Echinococcus granulosus mitogen activated protein kinase 0.0058 0.0133 0.0172
Trichomonas vaginalis conserved hypothetical protein 0.0027 0.0033 0.0071
Trichomonas vaginalis Clan CA, family C54, ATG4-like cysteine peptidase 0.0065 0.0156 0.0335
Echinococcus multilocularis zinc finger protein Ran binding 0.0525 0.1619 0.2092
Trichomonas vaginalis Clan SC, family S33, methylesterase-like serine peptidase 0.0087 0.0224 0.0482
Echinococcus multilocularis ring finger protein 170 0.0027 0.0033 0.0043
Mycobacterium ulcerans fatty-acid-CoA ligase 0.0043 0.0086 0.0065
Trichomonas vaginalis 2-deoxyglucose-6-phosphate phosphatase, putative 0.0082 0.0208 0.0448
Echinococcus multilocularis histone lysine N methyltransferase SETMAR 0.0031 0.0046 0.006
Trypanosoma cruzi hypothetical protein, conserved 0.0027 0.0033 0.0117
Schistosoma mansoni tar DNA-binding protein 0.0063 0.0147 0.0161
Brugia malayi Ligand-binding domain of nuclear hormone receptor family protein 0.0051 0.0111 0.024
Onchocerca volvulus Protein neuralized homolog 0.0027 0.0033 0.0071
Schistosoma mansoni fusion 0.0525 0.1619 0.1774
Brugia malayi hypothetical protein 0.0118 0.0324 0.0698
Echinococcus granulosus nuclear receptor 2DBD gamma 0.0051 0.0111 0.0144
Entamoeba histolytica hypothetical protein 0.0118 0.0324 0.3698
Trichomonas vaginalis Importin beta-1 subunit, putative 0.0024 0.0025 0.0054
Brugia malayi hypothetical protein 0.0017 0.0001 0.0003
Brugia malayi MH1 domain containing protein 0.0034 0.0056 0.0121
Onchocerca volvulus 0.0017 0.0001 0.0003
Leishmania major hypothetical protein, unknown function 0.0027 0.0033 0.0117
Toxoplasma gondii NADPH-glutathione reductase 0.0312 0.0942 0.2027
Mycobacterium tuberculosis Dihydrolipoamide dehydrogenase LpdC (lipoamide reductase (NADH)) (lipoyl dehydrogenase) (dihydrolipoyl dehydrogenase) (diaphoras 0.2286 0.7221 0.7215
Echinococcus granulosus Nuclear hormone receptor HR96 0.0024 0.0025 0.0032
Echinococcus multilocularis sulfide:quinone oxidoreductase 0.0083 0.0212 0.0274
Trichomonas vaginalis conserved hypothetical protein 0.0082 0.0208 0.0448
Echinococcus multilocularis retinoic acid receptor rxr beta a retinoic acid receptor rxr alpha a retinoic acid receptor rxr alpha 0.0024 0.0025 0.0032
Trypanosoma cruzi hypothetical protein, conserved 0.0525 0.1619 0.575
Mycobacterium tuberculosis Probable fatty-acid-CoA ligase FadD2 (fatty-acid-CoA synthetase) (fatty-acid-CoA synthase) 0.0043 0.0086 0.0065
Plasmodium falciparum ferrodoxin reductase-like protein 0.0083 0.0212 0.0456
Brugia malayi RNA recognition motif domain containing protein 0.0063 0.0147 0.0317
Mycobacterium ulcerans acyl-CoA synthetase 0.0043 0.0086 0.0065
Trichomonas vaginalis Importin beta-1 subunit, putative 0.0024 0.0025 0.0054
Trichomonas vaginalis glutathione reductase, putative 0.0312 0.0942 0.2027
Echinococcus multilocularis smad 0.0062 0.0144 0.0186
Echinococcus multilocularis muscleblind protein 0.0149 0.0423 0.0547
Echinococcus granulosus nuclear receptor nhr 48 0.0024 0.0025 0.0032
Trypanosoma cruzi dihydrolipoamide dehydrogenase, putative 0.0312 0.0942 0.3344
Trypanosoma cruzi UEV domain/Zinc finger, C3HC4 type (RING finger), putative 0.0027 0.0033 0.0117
Mycobacterium tuberculosis Possible epoxide hydrolase EphF (epoxide hydratase) (arene-oxide hydratase) 0.0087 0.0224 0.0203
Brugia malayi Pyruvate kinase, M2 isozyme 0.007 0.017 0.0367
Schistosoma mansoni hepatocyte nuclear factor 4-alpha (hnf-4-alpha) 0.0024 0.0025 0.0027
Echinococcus multilocularis lipoxygenase domain containing protein 0.0017 0.0001 0.0002
Trichomonas vaginalis disulfide oxidoreductase, putative 0.0083 0.0212 0.0456
Trypanosoma brucei predicted zinc finger protein 0.0027 0.0033 0.0053
Echinococcus multilocularis FTZ F1 alpha 0.0051 0.0111 0.0144
Giardia lamblia Protein 21.1 0.0027 0.0033 0.016
Trypanosoma brucei importin beta-1 subunit, putative 0.003 0.0043 0.009
Trypanosoma cruzi hydrolase-like protein, putative 0.0087 0.0224 0.0795
Brugia malayi YY1-associated factor 2 0.0525 0.1619 0.3485
Trypanosoma brucei DNA repair protein, putative 0.0027 0.0033 0.0053
Loa Loa (eye worm) hypothetical protein 0.0034 0.0056 0.0121
Trypanosoma cruzi Zinc finger, C3HC4 type (RING finger), putative 0.0027 0.0033 0.0117
Trichomonas vaginalis fructose-bisphosphate aldolase, putative 0.0292 0.0878 0.1889
Loa Loa (eye worm) nuclear hormone receptor family member nhr-14 0.0051 0.0111 0.024
Loa Loa (eye worm) glycosyl hydrolase family 31 protein 0.0139 0.039 0.0839
Trichomonas vaginalis hydrolase, putative 0.0087 0.0224 0.0482
Trypanosoma cruzi hypothetical protein, conserved 0.0031 0.0046 0.0163
Schistosoma mansoni choline dehydrogenase 0.0082 0.0208 0.0228
Giardia lamblia Protein 21.1 0.0027 0.0033 0.016
Plasmodium falciparum GTP-binding nuclear protein RAN/TC4 0.0022 0.0018 0.0039
Schistosoma mansoni ran 0.0022 0.0018 0.002
Loa Loa (eye worm) pigment dispersing factor receptor c 0.0204 0.0597 0.1285
Brugia malayi Pyridine nucleotide-disulphide oxidoreductase family protein 0.0083 0.0212 0.0456
Brugia malayi Pyridine nucleotide-disulphide oxidoreductase family protein 0.0083 0.0212 0.0456
Giardia lamblia Protein 21.1 0.0027 0.0033 0.016
Plasmodium vivax pyruvate kinase, putative 0.007 0.017 0.0367
Mycobacterium tuberculosis Probable fructose-bisphosphate aldolase Fba 0.0143 0.0402 0.0382
Trypanosoma cruzi Zinc finger, C3HC4 type (RING finger)/EF-hand domain pair, putative 0.0027 0.0033 0.0117
Trypanosoma brucei SNF2 family N-terminal domain/Ring finger domain containing protein, putative 0.0027 0.0033 0.0053
Giardia lamblia Protein 21.1 0.0027 0.0033 0.016
Chlamydia trachomatis thioredoxin reductase 0.0083 0.0212 0.0349
Loa Loa (eye worm) hypothetical protein 0.0027 0.0033 0.0071
Loa Loa (eye worm) hypothetical protein 0.0043 0.0086 0.0185
Loa Loa (eye worm) hypothetical protein 0.0051 0.0111 0.024
Entamoeba histolytica NAD(FAD)-dependent dehydrogenase, putative 0.0083 0.0212 0.2413
Echinococcus multilocularis protein dispatched 1 0.0088 0.0229 0.0296
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0062 0.0146 0.0458
Mycobacterium ulcerans epoxide hydrolase EphB 0.0087 0.0224 0.0203
Loa Loa (eye worm) abhydrolase domain-containing protein 2 0.0087 0.0224 0.0482
Leishmania major hydrolase-like protein,esterase-like protein 0.0087 0.0224 0.0795
Plasmodium falciparum thioredoxin reductase 0.0901 0.2816 0.6061
Trichomonas vaginalis dihydroorotate dehydrogenase, putative 0.0083 0.0212 0.0456
Loa Loa (eye worm) programmed cell death 8 0.0083 0.0212 0.0456
Trypanosoma cruzi cysteine peptidase, putative 0.0062 0.0146 0.052
Echinococcus granulosus jumonji domain containing protein 0.0042 0.0082 0.0105
Schistosoma mansoni zinc finger protein 0.0525 0.1619 0.1774
Trypanosoma brucei Zinc finger, C3HC4 type (RING finger), putative 0.0027 0.0033 0.0053
Trichomonas vaginalis fructose-bisphosphate aldolase, putative 0.0292 0.0878 0.1889
Trichomonas vaginalis glutamate synthase, putative 0.0083 0.0212 0.0456
Onchocerca volvulus Lipase homolog 0.0087 0.0224 0.0482
Trichomonas vaginalis pyruvate kinase, putative 0.007 0.017 0.0367
Leishmania major mitogen activated protein kinase, putative,map kinase, putative 0.0058 0.0133 0.0474
Mycobacterium ulcerans hydrolase 0.0082 0.0208 0.0187
Echinococcus multilocularis GPCR, family 2 0.0065 0.0153 0.0198
Toxoplasma gondii PHD-finger domain-containing protein 0.003 0.0044 0.0095
Onchocerca volvulus Lipase homolog 0.0087 0.0224 0.0482
Trypanosoma brucei Zinc finger, C3HC4 type (RING finger), putative 0.0027 0.0033 0.0053
Schistosoma mansoni hypothetical protein 0.1477 0.4646 0.5092
Mycobacterium ulcerans long-chain fatty-acid CoA ligase 0.0043 0.0086 0.0065
Echinococcus multilocularis dihydropyrimidine dehydrogenase (NADP+) 0.0083 0.0212 0.0274
Trypanosoma cruzi hypothetical protein, conserved 0.0027 0.0033 0.0117
Giardia lamblia Phosphoglycolate phosphatase 0.0082 0.0208 0.2056
Brugia malayi alpha keto acid dehydrogenase complex, E3 component, lipoamide dehydrogenase 0.0229 0.0678 0.1459
Trypanosoma brucei Zn-finger in Ran binding protein and others/FYVE zinc finger, putative 0.0525 0.1619 0.5722
Schistosoma mansoni tar DNA-binding protein 0.0063 0.0147 0.0161
Schistosoma mansoni smad 0.0062 0.0144 0.0158
Loa Loa (eye worm) hypothetical protein 0.0052 0.0113 0.0242
Plasmodium vivax ferrodoxin reductase, putative 0.0083 0.0212 0.0456
Echinococcus granulosus Transcription factor JmjC domain containing protein 0.0099 0.0262 0.0339
Echinococcus granulosus mothers against decapentaplegic 2 0.0028 0.0036 0.0046
Trichomonas vaginalis bromodomain-containing protein, putative 0.0043 0.0083 0.018
Trichomonas vaginalis conserved hypothetical protein 0.0027 0.0033 0.0071
Echinococcus granulosus RUN 0.0017 0.0001 0.0002
Loa Loa (eye worm) hypothetical protein 0.0149 0.0423 0.0911
Toxoplasma gondii hypothetical protein 0.0027 0.0033 0.0071
Leishmania major mitogen activated protein kinase 4, putative;with=GeneDB:LmxM19.1440 0.0058 0.0133 0.0474
Trypanosoma cruzi dihydrolipoamide dehydrogenase, putative 0.0312 0.0942 0.3344
Onchocerca volvulus 0.0043 0.0086 0.0185
Brugia malayi MH1 domain containing protein 0.0062 0.0144 0.031
Schistosoma mansoni hypothetical protein 0.0164 0.047 0.0515
Echinococcus granulosus glutamate synthase 0.0083 0.0212 0.0274
Trichomonas vaginalis conserved hypothetical protein 0.0027 0.0033 0.0071
Trypanosoma cruzi trypanothione reductase, putative 0.0901 0.2816 1
Giardia lamblia Fructose-bisphosphate aldolase 0.0292 0.0878 0.9303
Toxoplasma gondii pyridine nucleotide-disulfide oxidoreductase domain-containing protein 0.0083 0.0212 0.0456
Brugia malayi glutaminase DH11.1 0.0292 0.0878 0.1889
Brugia malayi Nuclear hormone receptor family member nhr-31 0.0051 0.0111 0.024
Trichomonas vaginalis 2-deoxyglucose-6-phosphate phosphatase, putative 0.0082 0.0208 0.0448
Trichomonas vaginalis conserved hypothetical protein 0.0082 0.0208 0.0448
Trichomonas vaginalis alpha-glucosidase, putative 0.0031 0.0046 0.0099
Loa Loa (eye worm) hypothetical protein 0.0027 0.0033 0.0071
Brugia malayi Latrophilin receptor protein 2 0.0065 0.0153 0.033
Echinococcus granulosus COUP TF:Svp nuclear hormone receptor 0.0138 0.0388 0.0501
Brugia malayi hypothetical protein 0.0017 0.0001 0.0003
Leishmania major cathepsin L-like protease 0.0062 0.0146 0.052
Toxoplasma gondii zinc finger, C3HC4 type (RING finger) domain-containing protein 0.0027 0.0033 0.0071
Echinococcus multilocularis mitogen activated protein kinase 0.0058 0.0133 0.0172
Mycobacterium ulcerans NADH dehydrogenase 0.0083 0.0212 0.0191
Echinococcus granulosus ring and YY1 binding protein 0.0525 0.1619 0.2092
Echinococcus multilocularis pyruvate kinase 0.007 0.017 0.022
Echinococcus granulosus mitogen activated protein kinase 3 0.0058 0.0133 0.0172
Trypanosoma cruzi Zinc finger, C3HC4 type (RING finger), putative 0.0027 0.0033 0.0117
Trypanosoma cruzi 2,4-dienoyl-coa reductase-like protein, putative 0.0083 0.0212 0.0752
Mycobacterium tuberculosis Probable exodeoxyribonuclease III protein XthA (exonuclease III) (EXO III) (AP endonuclease VI) 0.0038 0.0069 0.0048
Trypanosoma cruzi UEV domain/Zinc finger, C3HC4 type (RING finger), putative 0.0027 0.0033 0.0117
Toxoplasma gondii helicase, putative 0.0027 0.0033 0.0071
Plasmodium falciparum haloacid dehalogenase-like hydrolase, putative 0.0082 0.0208 0.0448
Loa Loa (eye worm) jmjC domain-containing protein 0.0037 0.0064 0.0138
Leishmania major 2,4-dihydroxyhept-2-ene-1,7-dioic acid aldolase, putative 0.0023 0.0021 0.0075
Loa Loa (eye worm) hypothetical protein 0.0024 0.0025 0.0054
Echinococcus multilocularis FTZ F1 nuclear receptor protein 0.0051 0.0111 0.0144
Trichomonas vaginalis ankyrin repeat domain protein, putative 0.0027 0.0033 0.0071
Echinococcus granulosus mothers against decapentaplegic 6 0.0028 0.0036 0.0046
Entamoeba histolytica zinc finger domain containing protein 0.0027 0.0033 0.0376
Trypanosoma cruzi dihydrolipoamide dehydrogenase, putative 0.0312 0.0942 0.3344
Leishmania major 2,4-dienoyl-coa reductase-like protein 0.0083 0.0212 0.0752
Echinococcus multilocularis thyroid hormone receptor alpha 0.0051 0.0111 0.0144
Loa Loa (eye worm) nuclear hormone receptor-like 1 0.0027 0.0034 0.0074
Onchocerca volvulus Mothers against decapentaplegic homolog 0.0028 0.0036 0.0077
Trypanosoma cruzi UEV domain/Zinc finger, C3HC4 type (RING finger), putative 0.0027 0.0033 0.0117
Mycobacterium leprae Probable hydrolase 0.0082 0.0208 0.0171
Trichomonas vaginalis 2-deoxyglucose-6-phosphate phosphatase, putative 0.0082 0.0208 0.0448
Onchocerca volvulus 0.0525 0.1619 0.3485
Echinococcus multilocularis nuclear receptor 2DBD gamma 0.0051 0.0111 0.0144
Schistosoma mansoni autophagin-1 (C54 family) 0.0065 0.0156 0.0171
Onchocerca volvulus 0.0245 0.0728 0.1567
Echinococcus multilocularis Niemann Pick C1 protein 0.0258 0.0768 0.0992
Loa Loa (eye worm) hypothetical protein 0.0525 0.1619 0.3485
Trypanosoma cruzi hypothetical protein, conserved 0.0087 0.0224 0.0795
Entamoeba histolytica SPRY domain protein 0.0027 0.0033 0.0376
Onchocerca volvulus Pyruvate kinase homolog 0.007 0.017 0.0367
Brugia malayi Corticotropin releasing factor receptor 2 precursor, putative 0.0204 0.0597 0.1285
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0062 0.0146 0.0458
Brugia malayi conserved hypotetical protein 0.0024 0.0025 0.0054
Brugia malayi nuclear hormone receptor 0.0051 0.0111 0.024
Trichomonas vaginalis alpha-glucosidase, putative 0.0031 0.0046 0.0099
Brugia malayi mothers against decapentaplegic homolog 3 0.0028 0.0036 0.0077
Onchocerca volvulus Phospholipase A2 homolog 0.0102 0.0272 0.0585
Brugia malayi Intermediate filament tail domain containing protein 0.0031 0.0046 0.0099
Brugia malayi Pyridine nucleotide-disulphide oxidoreductase, dimerisation domain containing protein 0.0229 0.0678 0.1459
Trichomonas vaginalis CMGC family protein kinase 0.0058 0.0133 0.0287
Loa Loa (eye worm) hypothetical protein 0.0032 0.0051 0.011
Schistosoma mansoni lipoxygenase 0.007 0.0172 0.0188
Entamoeba histolytica HAD hydrolase, family IA, variant 3 0.0082 0.0208 0.2371
Trypanosoma cruzi Zinc finger, C3HC4 type (RING finger), putative 0.0027 0.0033 0.0117
Schistosoma mansoni alpha glucosidase 0.0031 0.0046 0.005
Trichomonas vaginalis conserved hypothetical protein 0.0082 0.0208 0.0448
Trichomonas vaginalis set domain proteins, putative 0.0245 0.0728 0.1567
Trichomonas vaginalis mercuric reductase, putative 0.0312 0.0942 0.2027
Brugia malayi hypothetical protein 0.0027 0.0034 0.0074
Echinococcus granulosus lysine specific demethylase 5A 0.0037 0.0064 0.0083
Wolbachia endosymbiont of Brugia malayi NADPH-dependent glutamate synthase beta chain 0.0083 0.0212 0.1636
Trichomonas vaginalis Clan CA, family C54, ATG4-like cysteine peptidase 0.0065 0.0156 0.0335
Schistosoma mansoni microtubule-associated protein tau 0.227 0.7171 0.7858
Brugia malayi AMP-binding enzyme family protein 0.0043 0.0086 0.0185
Echinococcus multilocularis Nuclear hormone receptor HR96 0.0024 0.0025 0.0032
Schistosoma mansoni nuclear receptor nhr-48 0.0024 0.0025 0.0027
Echinococcus granulosus abhydrolase domain containing protein 3 0.0087 0.0224 0.0289
Echinococcus granulosus DNA apurinic or apyrimidinic site lyase 0.0038 0.0069 0.0089
Loa Loa (eye worm) haloacid dehalogenase-like hydrolase 0.0082 0.0208 0.0448
Echinococcus granulosus arachidonate 5 lipoxygenase 0.0101 0.0268 0.0346
Mycobacterium ulcerans hypothetical protein 0.0087 0.0224 0.0203
Brugia malayi Nuclear hormone receptor-like 1 0.0027 0.0034 0.0074
Loa Loa (eye worm) hypothetical protein 0.0032 0.0051 0.011
Schistosoma mansoni pyruvate kinase 0.007 0.017 0.0187
Giardia lamblia Protein 21.1 0.0027 0.0033 0.016
Entamoeba histolytica hypothetical protein 0.0027 0.0033 0.0376
Trichomonas vaginalis disulfide oxidoreductase, putative 0.0083 0.0212 0.0456
Mycobacterium leprae PROBABLE NADPH:ADRENODOXIN OXIDOREDUCTASE FPRB (ADRENODOXIN REDUCTASE) (AR) (FERREDOXIN-NADP(+) REDUCTASE) 0.0083 0.0212 0.0176
Trypanosoma cruzi cysteine peptidase, putative 0.0062 0.0146 0.052
Loa Loa (eye worm) hypothetical protein 0.003 0.0043 0.0093
Trichomonas vaginalis conserved hypothetical protein 0.0027 0.0033 0.0071
Schistosoma mansoni histone-lysine n-methyltransferase setb1 0.0031 0.0046 0.0051
Loa Loa (eye worm) hypothetical protein 0.0024 0.0025 0.0054
Schistosoma mansoni hypothetical protein 0.0071 0.0173 0.019
Trypanosoma brucei AUT2/APG4/ATG4 cysteine peptidase, putative 0.0065 0.0156 0.0491
Schistosoma mansoni alpha-glucosidase 0.012 0.0328 0.036
Trypanosoma cruzi GTP-binding nuclear protein rtb2, putative 0.0022 0.0018 0.0064
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0062 0.0146 0.0458
Trypanosoma cruzi Zn-finger in Ran binding protein and others/FYVE zinc finger, putative 0.0525 0.1619 0.575
Leishmania major hypothetical protein, conserved 0.0027 0.0033 0.0117
Loa Loa (eye worm) hypothetical protein 0.003 0.0044 0.0095
Loa Loa (eye worm) hypothetical protein 0.0082 0.0208 0.0448
Trypanosoma brucei Plus-3 domain/Zinc finger, C3HC4 type (RING finger), putative 0.0027 0.0033 0.0053
Toxoplasma gondii histone lysine acetyltransferase GCN5-B 0.0043 0.0083 0.018
Loa Loa (eye worm) MH2 domain-containing protein 0.0028 0.0036 0.0077
Plasmodium vivax haloacid dehalogenase-like hydrolase, putative 0.0082 0.0208 0.0448
Schistosoma mansoni nuclear receptor 0.0024 0.0025 0.0027
Loa Loa (eye worm) hypothetical protein 0.0017 0.0001 0.0003
Trypanosoma cruzi WLM domain containing protein, putative 0.0525 0.1619 0.575
Brugia malayi dihydrolipoyl dehydrogenase, mitochondrial precursor, putative 0.0312 0.0942 0.2027
Loa Loa (eye worm) MH1 domain-containing protein 0.0028 0.0036 0.0077
Echinococcus multilocularis lysosomal alpha glucosidase 0.0139 0.039 0.0504
Mycobacterium ulcerans long-chain-fatty-acid--CoA ligase 0.0043 0.0086 0.0065
Schistosoma mansoni 2-deoxyglucose-6-phosphate phosphatase 0.0082 0.0208 0.0228
Echinococcus multilocularis geminin 0.0164 0.047 0.0607
Trypanosoma brucei apurinic/apyrimidinic endonuclease, putative 0.0038 0.0069 0.0182
Mycobacterium ulcerans flavoprotein disulfide reductase 0.0312 0.0942 0.0923
Schistosoma mansoni hypothetical protein 0.0065 0.0153 0.0168
Mycobacterium ulcerans peroxidase BpoB 0.0087 0.0224 0.0203
Leishmania major hypothetical protein, conserved 0.0087 0.0224 0.0795
Mycobacterium ulcerans exported protease 0.0087 0.0224 0.0203
Loa Loa (eye worm) doublecortin family protein 0.0017 0.0001 0.0003
Giardia lamblia Phosphoglycolate phosphatase 0.0082 0.0208 0.2056
Schistosoma mansoni jumonji/arid domain-containing protein 0.0037 0.0064 0.007
Trichomonas vaginalis 2-deoxyglucose-6-phosphate phosphatase, putative 0.0082 0.0208 0.0448
Schistosoma mansoni glutamate synthase 0.0083 0.0212 0.0232
Trypanosoma cruzi pyridine nucleotide-disulphide oxidoreductase, putative 0.0083 0.0212 0.0752
Trichomonas vaginalis 2-deoxyglucose-6-phosphate phosphatase, putative 0.0082 0.0208 0.0448
Echinococcus granulosus lamin dm0 0.0031 0.0046 0.0059
Echinococcus multilocularis neutral alpha glucosidase AB 0.0031 0.0046 0.0059
Brugia malayi B-box zinc finger family protein 0.0027 0.0033 0.0071
Brugia malayi Steroid receptor seven-up type 2 0.0138 0.0388 0.0834
Mycobacterium leprae Probable pyruvate kinase PykA 0.007 0.017 0.0118
Schistosoma mansoni Tr4/Tr2 (homologue) 0.0051 0.0111 0.0122
Schistosoma mansoni histone-lysine n-methyltransferase setb1 0.0031 0.0046 0.0051
Echinococcus multilocularis protein patched 0.0077 0.0194 0.0251
Treponema pallidum phosphoglycolate phosphatase 0.0082 0.0208 0.1593
Trypanosoma brucei hypothetical protein, conserved 0.0082 0.0208 0.0679
Mycobacterium tuberculosis Fatty-acid-AMP ligase FadD30 (fatty-acid-AMP synthetase) (fatty-acid-AMP synthase) 0.0032 0.0051 0.003
Entamoeba histolytica fructose-1,6-bisphosphate aldolase, putative 0.0292 0.0878 1
Schistosoma mansoni TRABID protein (C64 family) 0.0525 0.1619 0.1774
Trypanosoma brucei pyridine nucleotide-disulphide oxidoreductase, putative 0.0083 0.0212 0.0692
Treponema pallidum fructose-bisphosphate aldolase 0.0292 0.0878 0.9263
Giardia lamblia Zinc finger domain 0.0027 0.0033 0.016
Echinococcus granulosus dihydropyrimidine dehydrogenase NADP 0.0083 0.0212 0.0274
Trichomonas vaginalis apoptosis inducing factor, putative 0.0083 0.0212 0.0456
Entamoeba histolytica acyl-CoA synthetase, putative 0.0043 0.0086 0.0981
Onchocerca volvulus 0.0031 0.0046 0.01
Trypanosoma brucei hypothetical protein, conserved 0.0525 0.1619 0.5722
Brugia malayi Nuclear hormone receptor family member nhr-25 0.0051 0.0111 0.024
Trypanosoma brucei pyruvate kinase 1, putative 0.007 0.017 0.0544
Schistosoma mansoni hypothetical protein 0.0075 0.0185 0.0203
Loa Loa (eye worm) hypothetical protein 0.0051 0.0111 0.024
Echinococcus granulosus Niemann Pick C1 protein 0.018 0.0522 0.0674
Trichomonas vaginalis ankyrin, putative 0.0027 0.0033 0.0071
Loa Loa (eye worm) hypothetical protein 0.0027 0.0033 0.0071
Schistosoma mansoni hypothetical protein 0.0118 0.0324 0.0356
Trypanosoma cruzi apurinic/apyrimidinic endonuclease 0.0038 0.0069 0.0245
Loa Loa (eye worm) glycosyl hydrolase family 31 protein 0.0031 0.0046 0.0099
Entamoeba histolytica thioredoxin reductase, putative 0.0083 0.0212 0.2413
Mycobacterium tuberculosis Probable haloalkane dehalogenase 0.0087 0.0224 0.0203
Trichomonas vaginalis conserved hypothetical protein 0.0027 0.0033 0.0071
Trypanosoma cruzi UEV domain/Zinc finger, C3HC4 type (RING finger), putative 0.0027 0.0033 0.0117
Leishmania major hypothetical protein 0.0027 0.0033 0.0117
Loa Loa (eye worm) CMGC/MAPK/ERK1 protein kinase 0.0058 0.0133 0.0287
Schistosoma mansoni family S33 non-peptidase homologue (S33 family) 0.0087 0.0224 0.0245
Plasmodium vivax hypothetical protein, conserved 0.1477 0.4646 1
Schistosoma mansoni family C54 unassigned peptidase (C54 family) 0.0065 0.0156 0.0171
Entamoeba histolytica acyl-coA synthetase, putative 0.0043 0.0086 0.0981
Trypanosoma cruzi 2,4-dihydroxyhept-2-ene-1,7-dioic acid aldolase, putative 0.0023 0.0021 0.0075
Toxoplasma gondii glycosyl hydrolase, family 31 protein 0.0031 0.0046 0.0099
Schistosoma mansoni transcription factor LCR-F1 0.0118 0.0324 0.0356
Brugia malayi nuclear receptor NHR-88 0.0024 0.0025 0.0054
Plasmodium falciparum RING zinc finger protein, putative 0.0027 0.0033 0.0071
Schistosoma mansoni ap endonuclease 0.0038 0.0069 0.0076
Schistosoma mansoni Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) 0.0126 0.0347 0.0381
Schistosoma mansoni Smad4 0.0062 0.0144 0.0158
Mycobacterium ulcerans acyl-CoA synthetase 0.0043 0.0086 0.0065
Echinococcus multilocularis Smad4 0.0062 0.0144 0.0186
Trypanosoma cruzi AUT2/APG4/ATG4 cysteine peptidase, putative 0.0065 0.0156 0.0553
Leishmania major hypothetical protein, conserved 0.0525 0.1619 0.575
Brugia malayi haloacid dehalogenase-like hydrolase family protein 0.0082 0.0208 0.0448
Schistosoma mansoni hypothetical protein 0.0075 0.0185 0.0203
Schistosoma mansoni survival motor neuron protein 0.0041 0.0079 0.0086
Loa Loa (eye worm) ab-hydrolase associated lipase region family protein 0.0087 0.0224 0.0482
Trichomonas vaginalis ankyrin repeat-containing protein, putative 0.0027 0.0033 0.0071
Mycobacterium ulcerans lignin peroxidase LipJ 0.0087 0.0224 0.0203
Schistosoma mansoni glutamate synthase 0.0083 0.0212 0.0232
Mycobacterium leprae POSSIBLE EPOXIDE HYDROLASE EPHE (EPOXIDE HYDRATASE) (ARENE-OXIDE HYDRATASE) 0.0087 0.0224 0.0193
Trypanosoma brucei dihydrolipoamide dehydrogenase 0.0312 0.0942 0.3301
Mycobacterium ulcerans long-chain-fatty-acid-CoA ligase 0.0043 0.0086 0.0065
Plasmodium vivax NAD(P)H-dependent glutamate synthase, putative 0.0083 0.0212 0.0456
Plasmodium falciparum acid cluster protein 33 homologue, putative 0.0087 0.0224 0.0482
Trichomonas vaginalis 2-deoxyglucose-6-phosphate phosphatase, putative 0.0082 0.0208 0.0448
Schistosoma mansoni nuclear receptor 0.0024 0.0025 0.0027
Brugia malayi Alpha/beta hydrolase 0.0087 0.0224 0.0482
Loa Loa (eye worm) hypothetical protein 0.0051 0.0111 0.024
Trypanosoma cruzi hydrolase-like protein, putative 0.0087 0.0224 0.0795
Trypanosoma cruzi hypothetical protein, conserved 0.0087 0.0224 0.0795
Brugia malayi RNA, U transporter 1 0.0085 0.0219 0.0472
Trypanosoma cruzi pyruvate kinase 2, putative 0.007 0.017 0.0605
Trichomonas vaginalis ankyrin, putative 0.0027 0.0033 0.0071
Entamoeba histolytica peptidase, C54 family 0.0025 0.0029 0.033
Trichomonas vaginalis glucosylceramidase, putative 0.0168 0.0481 0.1036
Trichomonas vaginalis valacyclovir hydrolase, putative 0.0087 0.0224 0.0482
Mycobacterium ulcerans fructose-bisphosphate aldolase 0.0143 0.0402 0.0382
Schistosoma mansoni hypothetical protein 0.0017 0.0001 0.0002
Trypanosoma brucei dihydrolipoamide dehydrogenase 0.0312 0.0942 0.3301
Echinococcus multilocularis histone lysine methyltransferase setb histone lysine methyltransferase eggless 0.0031 0.0046 0.006
Mycobacterium tuberculosis Probable homoserine O-acetyltransferase MetA (homoserine O-trans-acetylase) (homoserine transacetylase) (HTA) 0.0087 0.0224 0.0203
Echinococcus granulosus lipoxygenase domain containing protein 0.0017 0.0001 0.0002
Echinococcus granulosus sulfide:quinone oxidoreductase 0.0083 0.0212 0.0274
Schistosoma mansoni Smad4 0.0028 0.0036 0.0039
Echinococcus granulosus SWI:SNF matrix associated 0.1477 0.4646 0.6003
Onchocerca volvulus 0.0358 0.1088 0.2343
Trypanosoma cruzi hydrolase, alpha/beta fold family, putative 0.0087 0.0224 0.0795
Plasmodium falciparum LCCL domain-containing protein 0.0017 0.0001 0.0003
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0062 0.0146 0.0458
Leishmania major hypothetical protein, conserved 0.0027 0.0033 0.0117
Loa Loa (eye worm) hypothetical protein 0.0027 0.0034 0.0074
Trichomonas vaginalis alpha-glucosidase, putative 0.0031 0.0046 0.0099
Brugia malayi MH2 domain containing protein 0.0028 0.0036 0.0077
Entamoeba histolytica alpha/beta hydrolase fold protein, putative 0.0087 0.0224 0.2552
Loa Loa (eye worm) hypothetical protein 0.0024 0.0025 0.0054
Loa Loa (eye worm) nuclear receptor NHR-67 0.0024 0.0025 0.0054
Trypanosoma cruzi 2,4-dienoyl-coa reductase fadh1, putative 0.0083 0.0212 0.0752
Brugia malayi MH2 domain containing protein 0.0062 0.0144 0.031
Brugia malayi Hypothetical RING finger protein C16C10.7 in chromosome III 0.0027 0.0033 0.0071
Plasmodium vivax hypothetical protein, conserved 0.0087 0.0224 0.0482
Mycobacterium tuberculosis Probable NADPH:adrenodoxin oxidoreductase FprB (adrenodoxin reductase) (AR) (ferredoxin-NADP(+) reductase) 0.0083 0.0212 0.0191
Echinococcus granulosus cadherin EGF LAG seven pass G type receptor 0.0065 0.0153 0.0198
Loa Loa (eye worm) hypothetical protein 0.0525 0.1619 0.3485
Trypanosoma cruzi apurinic/apyrimidinic endonuclease, putative 0.0038 0.0069 0.0245
Trypanosoma brucei hydrolase, alpha/beta fold family, putative 0.0087 0.0224 0.0735
Schistosoma mansoni steroid hormone receptor ad4bp 0.0051 0.0111 0.0122
Trichomonas vaginalis conserved hypothetical protein 0.0027 0.0033 0.0071
Trichomonas vaginalis 2-deoxyglucose-6-phosphate phosphatase, putative 0.0082 0.0208 0.0448
Brugia malayi UPF0017 protein CG3488 0.0087 0.0224 0.0482
Toxoplasma gondii ran binding protein 0.0525 0.1619 0.3485
Trichomonas vaginalis conserved hypothetical protein 0.0027 0.0033 0.0071
Loa Loa (eye worm) Smad1 0.0062 0.0144 0.031
Brugia malayi ecdysone receptor 0.0024 0.0025 0.0054
Plasmodium falciparum importin beta, putative 0.003 0.0043 0.0093
Trypanosoma brucei importin beta-1 subunit, putative 0.003 0.0043 0.009
Loa Loa (eye worm) hypothetical protein 0.0024 0.0025 0.0054
Schistosoma mansoni lamin 0.0031 0.0046 0.005
Schistosoma mansoni ecdysone-induced protein 78c (dr-78) 0.0027 0.0034 0.0038
Mycobacterium leprae Probable exported protease 0.0087 0.0224 0.0193
Chlamydia trachomatis phosphoglycolate phosphatase 0.0082 0.0208 0.0341
Mycobacterium ulcerans glutaminase 0.0292 0.0878 0.0858
Schistosoma mansoni zinc finger protein 0.0027 0.0033 0.0036
Trichomonas vaginalis dihydroorotate dehydrogenase, putative 0.0083 0.0212 0.0456
Entamoeba histolytica glycosyl hydrolase, family 31 protein 0.0031 0.0046 0.0524
Mycobacterium leprae Possible short-chain dehydrogenase EphD 0.0087 0.0224 0.0193
Trypanosoma cruzi Plus-3 domain/Zinc finger, C3HC4 type (RING finger), putative 0.0027 0.0033 0.0117
Onchocerca volvulus 0.0031 0.0046 0.0099
Brugia malayi Nuclear hormone receptor family member nhr-41 0.0051 0.0111 0.024
Schistosoma mansoni nuclear hormone receptor superfamily protein-related 0.0024 0.0025 0.0027
Trypanosoma cruzi 2,4-dihydroxyhept-2-ene-1,7-dioic acid aldolase, putative 0.0023 0.0021 0.0075
Echinococcus granulosus pyruvate kinase 0.0036 0.0062 0.008
Loa Loa (eye worm) hypothetical protein 0.0114 0.0311 0.0668
Toxoplasma gondii pyridine nucleotide-disulfide oxidoreductase domain-containing protein 0.0083 0.0212 0.0456
Plasmodium vivax hypothetical protein, conserved 0.0087 0.0224 0.0482
Plasmodium vivax hypothetical protein, conserved 0.003 0.0044 0.0095
Trypanosoma cruzi dihydrolipoamide dehydrogenase, putative 0.0312 0.0942 0.3344
Mycobacterium tuberculosis Possible dehydrogenase/reductase 0.0083 0.0212 0.0191
Schistosoma mansoni patched 1 0.0077 0.0194 0.0213
Trypanosoma brucei Zinc finger, C3HC4 type (RING finger), putative 0.0027 0.0033 0.0053
Loa Loa (eye worm) hypothetical protein 0.0051 0.0111 0.024
Schistosoma mansoni rab6-interacting 0.0017 0.0001 0.0002
Echinococcus multilocularis E3 ubiquitin protein ligase Bre1 0.0027 0.0033 0.0043
Leishmania major pyruvate kinase 0.007 0.017 0.0605
Echinococcus multilocularis survival motor neuron protein 1 0.0202 0.0589 0.0761
Trypanosoma cruzi cysteine peptidase, putative 0.0062 0.0146 0.052
Trypanosoma brucei Plus-3 domain/Zinc finger, C3HC4 type (RING finger), putative 0.0027 0.0033 0.0053
Trichomonas vaginalis hypothetical protein 0.0027 0.0033 0.0071
Plasmodium falciparum epoxide hydrolase 1 0.0087 0.0224 0.0482
Echinococcus multilocularis arachidonate 5 lipoxygenase 0.0101 0.0268 0.0346
Trypanosoma brucei protein kinase, putative 0.0058 0.0133 0.0412
Echinococcus multilocularis lysosomal acid lipase:cholesteryl ester 0.0087 0.0224 0.0289
Entamoeba histolytica pyruvate kinase, putative 0.0049 0.0103 0.1175
Giardia lamblia Protein 21.1 0.0027 0.0033 0.016
Brugia malayi Nuclear hormone receptor family member nhr-25 0.0051 0.0111 0.024
Loa Loa (eye worm) nuclear hormone receptor family member nhr-1 0.0051 0.0111 0.024
Trypanosoma cruzi UEV domain/Zinc finger, C3HC4 type (RING finger), putative 0.0027 0.0033 0.0117
Echinococcus multilocularis abhydrolase domain containing protein 11 0.0087 0.0224 0.0289
Entamoeba histolytica glutamate synthase beta subunit, putative 0.0083 0.0212 0.2413
Leishmania major 2,4-dienoyl-coa reductase fadh1, putative 0.0083 0.0212 0.0752
Echinococcus granulosus lysosomal acid lipase:cholesteryl ester 0.0087 0.0224 0.0289
Loa Loa (eye worm) hypothetical protein 0.0032 0.0051 0.011
Plasmodium falciparum pyruvate kinase 0.007 0.017 0.0367
Echinococcus granulosus nuclear receptor subfamily 1 group D 0.0027 0.0034 0.0044
Brugia malayi Iron-sulfur cluster assembly accessory protein 0.0041 0.0079 0.0169
Brugia malayi Calcitonin receptor-like protein seb-1 0.0204 0.0597 0.1285
Mycobacterium ulcerans NADPH dependent 2,4-dienoyl-CoA reductase FadH 0.0083 0.0212 0.0191
Trichomonas vaginalis CMGC family protein kinase 0.0058 0.0133 0.0287
Mycobacterium tuberculosis Possible peroxidase BpoB (non-haem peroxidase) 0.0087 0.0224 0.0203
Entamoeba histolytica hypothetical protein 0.0118 0.0324 0.3698
Toxoplasma gondii Zn-finger in Ran binding protein and others domain-containing protein 0.0525 0.1619 0.3485
Entamoeba histolytica hypothetical protein 0.0118 0.0324 0.3698
Giardia lamblia Protein 21.1 0.0027 0.0033 0.016
Brugia malayi hypothetical protein 0.0024 0.0025 0.0054
Echinococcus multilocularis guanine nucleotide binding protein G(s) subunit 0.0126 0.0347 0.0449
Trichomonas vaginalis glucosylceramidase, putative 0.0255 0.0761 0.1637
Echinococcus granulosus dihydrolipoamide dehydrogenase 0.0312 0.0942 0.1217
Schistosoma mansoni cellular tumor antigen P53 0.0358 0.1088 0.1193
Giardia lamblia Protein 21.1 0.0027 0.0033 0.016
Wolbachia endosymbiont of Brugia malayi dihydrolipoamide dehydrogenase E3 component 0.0312 0.0942 1
Echinococcus multilocularis importin subunit beta 1 0.003 0.0043 0.0056
Entamoeba histolytica fructose-1,6-bisphosphate aldolase, putative 0.0292 0.0878 1
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0062 0.0146 0.0458
Trichomonas vaginalis ap endonuclease, putative 0.0038 0.0069 0.0148
Schistosoma mansoni peter pan-related 0.0027 0.0033 0.0036
Trypanosoma brucei hypothetical protein, conserved 0.0083 0.0212 0.0692
Echinococcus multilocularis lamin 0.0031 0.0046 0.0059
Brugia malayi photoreceptor-specific nuclear receptor 0.0051 0.0111 0.024
Echinococcus multilocularis abhydrolase domain containing protein 0.0087 0.0224 0.0289
Chlamydia trachomatis DNA topoisomerase I 0.1477 0.4646 1
Mycobacterium ulcerans glutamate synthase subunit beta 0.0083 0.0212 0.0191
Echinococcus granulosus smad 0.0062 0.0144 0.0186
Leishmania major hypothetical protein, conserved 0.02 0.0583 0.207
Trypanosoma cruzi UEV domain/Zinc finger, C3HC4 type (RING finger), putative 0.0027 0.0033 0.0117
Schistosoma mansoni hypothetical protein 0.1477 0.4646 0.5092
Echinococcus granulosus Zinc finger RanBP2 type 0.0525 0.1619 0.2092
Trichomonas vaginalis glucosylceramidase, putative 0.0168 0.0481 0.1036
Echinococcus granulosus sterol regulatory element binding protein 0.0077 0.0194 0.0251
Mycobacterium ulcerans oxidoreductase 0.0087 0.0224 0.0203
Plasmodium vivax glutathione reductase, putative 0.0901 0.2816 0.6061
Brugia malayi nuclear receptor RXR 0.0027 0.0034 0.0074
Loa Loa (eye worm) hypothetical protein 0.0017 0.0001 0.0003
Schistosoma mansoni pyruvate kinase 0.007 0.017 0.0187
Trichomonas vaginalis conserved hypothetical protein 0.0082 0.0208 0.0448
Leishmania major apurinic/apyrimidinic endonuclease-redox protein 0.0038 0.0069 0.0245
Schistosoma mansoni ran 0.0022 0.0018 0.002
Echinococcus multilocularis 0.0027 0.0033 0.0043
Mycobacterium leprae Probable NADPH:adrenodoxin oxidoreductase FprA (NADPH-FERREDOXIN REDUCTASE) 0.0083 0.0212 0.0176
Trichomonas vaginalis cat eye syndrome critical region protein 2, cscr2, putative 0.0043 0.0083 0.018
Giardia lamblia Kinase, NEK 0.0027 0.0035 0.0179
Brugia malayi Nuclear hormone receptor family member nhr-19 0.0051 0.0111 0.024
Mycobacterium tuberculosis Probable dehydrogenase 0.2056 0.6491 0.6483
Echinococcus granulosus Basic leucine zipper bZIP transcription 0.0118 0.0324 0.0419
Mycobacterium ulcerans exodeoxyribonuclease III protein XthA 0.0038 0.0069 0.0048
Schistosoma mansoni hypothetical protein 0.0065 0.0153 0.0168
Trypanosoma cruzi mitogen-activated protein kinase 11, putative 0.0058 0.0133 0.0474
Echinococcus granulosus nuclear receptor subfamily 4 group A 0.0024 0.0025 0.0032
Trypanosoma cruzi Zinc finger, C3HC4 type (RING finger)/EF-hand domain pair, putative 0.0027 0.0033 0.0117
Trypanosoma cruzi Zinc finger, C3HC4 type (RING finger), putative 0.0027 0.0033 0.0117
Entamoeba histolytica haloacid dehalogenase-like hydrolase domain-containing protein 0.0082 0.0208 0.2371
Schistosoma mansoni ap endonuclease 0.0038 0.0069 0.0076
Schistosoma mansoni nuclear hormone receptor 0.0051 0.0111 0.0122
Giardia lamblia Hypothetical protein 0.0027 0.0033 0.016
Mycobacterium ulcerans thioredoxin reductase TrxB2 0.0083 0.0212 0.0191
Giardia lamblia Hypothetical protein 0.0027 0.0033 0.016
Toxoplasma gondii zinc finger, C3HC4 type (RING finger) domain-containing protein 0.0027 0.0033 0.0071
Schistosoma mansoni hypothetical protein 0.0139 0.0392 0.0429
Entamoeba histolytica peptidase, C54 family 0.0025 0.0029 0.033
Loa Loa (eye worm) acetyltransferase 0.0145 0.0409 0.088
Echinococcus granulosus dihydropyrimidine dehydrogenase NADP 0.0083 0.0212 0.0274
Echinococcus multilocularis haloacid dehalogenase hydrolase 0.0082 0.0208 0.0269
Echinococcus granulosus E3 ubiquitin protein ligase mib1 0.0027 0.0033 0.0043
Brugia malayi cytoplasmic intermediate filament protein 0.0016 0 0.0001
Echinococcus multilocularis lipoxygenase domain containing protein 0.0017 0.0001 0.0002
Trypanosoma cruzi hypothetical protein, conserved 0.0031 0.0046 0.0163
Loa Loa (eye worm) pyruvate kinase 0.007 0.017 0.0367
Loa Loa (eye worm) hypothetical protein 0.0149 0.0423 0.0911
Echinococcus granulosus Protein patched homolog 1 0.0077 0.0194 0.0251
Loa Loa (eye worm) TAR-binding protein 0.0063 0.0147 0.0317
Echinococcus multilocularis RING finger protein 185 0.0027 0.0033 0.0043
Mycobacterium ulcerans hydrolase 0.0087 0.0224 0.0203
Toxoplasma gondii pyruvate dehydrogenase complex subunit PDH-E3II 0.0312 0.0942 0.2027
Trichomonas vaginalis conserved hypothetical protein 0.0027 0.0033 0.0071
Giardia lamblia ENC6 protein 0.0087 0.0224 0.2227
Brugia malayi GTP-binding regulatory protein Gs alpha-S chain, putative 0.0126 0.0347 0.0748
Brugia malayi Zinc finger, C2H2 type family protein 0.0027 0.0033 0.0071
Loa Loa (eye worm) pyruvate kinase-PB 0.0049 0.0103 0.0222
Echinococcus granulosus abhydrolase domain containing protein 0.0087 0.0224 0.0289
Echinococcus multilocularis SWI:SNF matrix associated 0.1477 0.4646 0.6003
Echinococcus granulosus peregrin 0.0034 0.0055 0.0071
Brugia malayi RING finger protein 20 0.0027 0.0033 0.0071
Mycobacterium ulcerans 2-hydroxy-6-oxo-6-phenylhexa-2,4-dienoate hydrolase BphD 0.0087 0.0224 0.0203
Toxoplasma gondii PHD-finger domain-containing protein 0.003 0.0044 0.0095
Trypanosoma brucei hypothetical protein, conserved 0.0525 0.1619 0.5722
Trichomonas vaginalis 2-deoxyglucose-6-phosphate phosphatase, putative 0.0082 0.0208 0.0448
Giardia lamblia E3 ubiquitin ligase for Rad6p required for the ubiquitination of histone H2B 0.0027 0.0033 0.016
Schistosoma mansoni hypothetical protein 0.003 0.0044 0.0048
Leishmania major NADH dehydrogenase, putative 0.0083 0.0212 0.0752
Loa Loa (eye worm) hypothetical protein 0.0024 0.0025 0.0054
Onchocerca volvulus 0.0024 0.0025 0.0054
Giardia lamblia Protein 21.1 0.0027 0.0033 0.016
Echinococcus granulosus Niemann Pick C1 protein 0.0258 0.0768 0.0992
Schistosoma mansoni mind bomb 0.0027 0.0033 0.0036
Trypanosoma cruzi hypothetical protein, conserved 0.0027 0.0033 0.0117
Giardia lamblia Thioredoxin reductase 0.0083 0.0212 0.2096
Brugia malayi TAR-binding protein 0.0063 0.0147 0.0317
Echinococcus multilocularis Niemann Pick C1 protein 0.018 0.0522 0.0674
Trypanosoma cruzi cruzipain precursor, putative 0.0062 0.0146 0.052
Trypanosoma cruzi Plus-3 domain/Zinc finger, C3HC4 type (RING finger), putative 0.0027 0.0033 0.0117
Schistosoma mansoni glutamate synthase 0.0083 0.0212 0.0232
Loa Loa (eye worm) intermediate filament tail domain-containing protein 0.0031 0.0046 0.0099
Brugia malayi hypothetical protein 0.0027 0.0033 0.0071
Schistosoma mansoni hypothetical protein 0.1477 0.4646 0.5092
Giardia lamblia Ribonuclease 0.0027 0.0033 0.016
Trichomonas vaginalis fructose-bisphosphate aldolase, putative 0.0292 0.0878 0.1889
Trypanosoma brucei dihydrolipoyl dehydrogenase 0.0312 0.0942 0.3301
Brugia malayi nuclear hormone receptor family member nhr-6 0.0024 0.0025 0.0054
Echinococcus granulosus RING finger protein 185 0.0027 0.0033 0.0043
Echinococcus granulosus histone acetyltransferase KAT2B 0.0141 0.0396 0.0512
Entamoeba histolytica hypothetical protein 0.0087 0.0224 0.2552
Echinococcus granulosus Polycystic kidney disease protein 0.0017 0.0001 0.0002
Loa Loa (eye worm) exodeoxyribonuclease III family protein 0.0038 0.0069 0.0148
Echinococcus multilocularis ring and YY1 binding protein 0.0525 0.1619 0.2092
Mycobacterium ulcerans hypothetical protein 0.0082 0.0208 0.0187
Brugia malayi hypothetical protein 0.0027 0.0033 0.0071
Toxoplasma gondii exonuclease III APE 0.0038 0.0069 0.0148
Leishmania major pyruvate kinase 0.007 0.017 0.0605
Trypanosoma cruzi hypothetical protein, conserved 0.0525 0.1619 0.575
Brugia malayi glutathione reductase 0.0901 0.2816 0.6061
Plasmodium vivax SET domain protein, putative 0.0031 0.0046 0.01
Trichomonas vaginalis glucosylceramidase, putative 0.0177 0.051 0.1098
Trichomonas vaginalis neutral alpha-glucosidase ab precursor, putative 0.0031 0.0046 0.0099
Leishmania major 4-coumarate:coa ligase-like protein 0.0043 0.0086 0.0306
Mycobacterium ulcerans NADPH:adrenodoxin oxidoreductase FprA 0.0083 0.0212 0.0191
Brugia malayi hypothetical protein 0.0027 0.0033 0.0071
Brugia malayi haloacid dehalogenase-like hydrolase family protein 0.0082 0.0208 0.0448
Brugia malayi orphan nuclear receptor NR2E1 0.0024 0.0025 0.0054
Mycobacterium ulcerans proline iminopeptidase PIP 0.0087 0.0224 0.0203
Echinococcus granulosus hepatocyte nuclear factor 4 alpha 0.0051 0.0111 0.0144
Echinococcus multilocularis DNA (apurinic or apyrimidinic site) lyase 0.0038 0.0069 0.0089
Brugia malayi PHD-finger family protein 0.003 0.0044 0.0095
Giardia lamblia Protein 21.1 0.0027 0.0033 0.016
Loa Loa (eye worm) hypothetical protein 0.0024 0.0025 0.0054
Brugia malayi SWIB/MDM2 domain containing protein 0.1477 0.4646 1
Onchocerca volvulus Protein ultraspiracle homolog 0.0051 0.0111 0.024
Echinococcus multilocularis jumonji domain containing protein 0.0042 0.0082 0.0105
Mycobacterium tuberculosis Possible phosphatase 0.0082 0.0208 0.0187
Leishmania major hydrolase, alpha/beta fold family, putative 0.0087 0.0224 0.0795
Loa Loa (eye worm) hypothetical protein 0.0027 0.0033 0.0071
Onchocerca volvulus Huntingtin homolog 0.0104 0.028 0.0603
Loa Loa (eye worm) hypothetical protein 0.0494 0.1518 0.3268
Trichomonas vaginalis conserved hypothetical protein 0.0027 0.0033 0.0071
Plasmodium falciparum glutathione reductase 0.0312 0.0942 0.2027
Trypanosoma cruzi pyridine nucleotide-disulphide oxidoreductase, putative 0.0083 0.0212 0.0752
Giardia lamblia Glutamate synthase 0.0083 0.0212 0.2096
Leishmania major AUT2/APG4/ATG4 cysteine peptidase, putative 0.0065 0.0156 0.0553
Trichomonas vaginalis glucosylceramidase, putative 0.0255 0.0761 0.1637
Trichomonas vaginalis CMGC family protein kinase 0.0058 0.0133 0.0287
Brugia malayi nuclear hormone receptor 0.0024 0.0025 0.0054
Trichomonas vaginalis glucosylceramidase, putative 0.0255 0.0761 0.1637
Loa Loa (eye worm) abnormal chemotaxis protein 14 0.0077 0.0194 0.0418
Trichomonas vaginalis glucosylceramidase, putative 0.0168 0.0481 0.1036
Loa Loa (eye worm) intermediate filament protein 0.0031 0.0046 0.0099
Onchocerca volvulus 0.0051 0.0111 0.024
Mycobacterium tuberculosis Conserved protein 0.0087 0.0224 0.0203
Leishmania major GTP-binding protein, putative 0.0022 0.0018 0.0064
Leishmania major DNA repair protein-like protein 0.0027 0.0033 0.0117
Echinococcus granulosus diuretic hormone 44 receptor GPRdih2 0.0065 0.0153 0.0198
Plasmodium falciparum SWIB/MDM2 domain-containing protein 0.1477 0.4646 1
Trypanosoma cruzi hypothetical protein, conserved 0.0087 0.0224 0.0795
Loa Loa (eye worm) hypothetical protein 0.0065 0.0156 0.0335
Echinococcus multilocularis snurportin 1 0.032 0.0966 0.1249
Brugia malayi Nuclear hormone receptor-like 1 0.0051 0.0111 0.024
Echinococcus granulosus mothers against decapentaplegic 5 0.0062 0.0144 0.0186
Trichomonas vaginalis ubiquitin-protein ligase BRE1, putative 0.0027 0.0033 0.0071
Loa Loa (eye worm) hypothetical protein 0.0139 0.0392 0.0843
Mycobacterium tuberculosis Probable hydrolase 0.0082 0.0208 0.0187
Schistosoma mansoni RNA binding protein 0.0525 0.1619 0.1774
Onchocerca volvulus Ubiquitin thioesterase ZRANB1 homolog 0.0525 0.1619 0.3485
Toxoplasma gondii CMGC kinase, MAPK family (ERK) MAPK-1 0.0058 0.0133 0.0287
Onchocerca volvulus Phospholipase A2 homolog 0.0484 0.1487 0.3201
Brugia malayi hypothetical protein 0.0202 0.0589 0.1268
Plasmodium vivax alpha/beta hydrolase, putative 0.0087 0.0224 0.0482
Giardia lamblia Hydrolase, haloacid dehalogenase-like family 0.0082 0.0208 0.2056
Trichomonas vaginalis Clan CA, family C54, ATG4-like cysteine peptidase 0.0065 0.0156 0.0335
Wolbachia endosymbiont of Brugia malayi thioredoxin reductase 0.0083 0.0212 0.1636
Plasmodium falciparum E3 ubiquitin-protein ligase, putative 0.0027 0.0033 0.0071
Trichomonas vaginalis conserved hypothetical protein 0.0027 0.0033 0.0071
Echinococcus multilocularis nuclear receptor 2DBD gamma 0.0024 0.0025 0.0032
Loa Loa (eye worm) SWIB/MDM2 domain-containing protein 0.1477 0.4646 1
Onchocerca volvulus 0.0082 0.0208 0.0448
Loa Loa (eye worm) hypothetical protein 0.0027 0.0033 0.0071
Trichomonas vaginalis 2-deoxyglucose-6-phosphate phosphatase, putative 0.0082 0.0208 0.0448
Brugia malayi Smad1 0.0062 0.0144 0.031
Echinococcus multilocularis dihydrolipoamide dehydrogenase 0.0312 0.0942 0.1217
Trichomonas vaginalis conserved hypothetical protein 0.0027 0.0033 0.0071
Trichomonas vaginalis 2-deoxyglucose-6-phosphate phosphatase, putative 0.0082 0.0208 0.0448
Echinococcus multilocularis PHD finger protein rhinoceros 0.003 0.0044 0.0057
Trypanosoma cruzi Zn-finger in Ran binding protein and others, putative 0.0525 0.1619 0.575
Trichomonas vaginalis Citrate lyase beta chain, putative 0.0023 0.0021 0.0045
Trichomonas vaginalis conserved hypothetical protein 0.1477 0.4646 1
Brugia malayi Nuclear hormone receptor family member nhr-19 0.0051 0.0111 0.024
Echinococcus granulosus geminin 0.0164 0.047 0.0607
Brugia malayi Nuclear hormone receptor E75 0.0024 0.0025 0.0054
Mycobacterium tuberculosis Putative ferredoxin reductase 0.2056 0.6491 0.6483
Mycobacterium ulcerans hypothetical protein 0.0043 0.0086 0.0065
Echinococcus granulosus ecdysone induced protein 78C 0.0051 0.0111 0.0144
Loa Loa (eye worm) pyruvate kinase 0.007 0.017 0.0367
Entamoeba histolytica dihydropyrimidine dehydrogenase, putative 0.0083 0.0212 0.2413
Mycobacterium leprae POSSIBLE SECRETED PROTEASE 0.0087 0.0224 0.0193
Giardia lamblia Protein 21.1 0.0027 0.0033 0.016
Leishmania major hydrolase, alpha/beta fold family-like protein 0.0087 0.0224 0.0795
Trypanosoma brucei UEV domain/Zinc finger, C3HC4 type (RING finger), putative 0.0027 0.0033 0.0053
Schistosoma mansoni retinoid-x-receptor (RXR) 0.0027 0.0034 0.0038
Schistosoma mansoni lipoxygenase 0.0101 0.0268 0.0293
Giardia lamblia Protein 21.1 0.0027 0.0033 0.016
Trypanosoma cruzi cysteine peptidase, Clan CA, family C54, putative 0.0025 0.0029 0.0103
Echinococcus granulosus neutral alpha glucosidase AB 0.0031 0.0046 0.0059
Toxoplasma gondii selenide, water dikinase 0.0083 0.0212 0.0456
Echinococcus granulosus snurportin 1 0.032 0.0966 0.1249
Echinococcus granulosus tumor protein p63 0.2449 0.774 1
Entamoeba histolytica zinc finger domain containing protein 0.0027 0.0033 0.0376
Loa Loa (eye worm) thioredoxin reductase 0.0901 0.2816 0.6061
Brugia malayi hypothetical protein 0.0104 0.028 0.0603
Trichomonas vaginalis glucosylceramidase, putative 0.0255 0.0761 0.1637
Schistosoma mansoni coup transcription factor 0.0051 0.0111 0.0122
Plasmodium falciparum cysteine protease ATG4, putative 0.0025 0.0029 0.0062
Schistosoma mansoni nuclear hormone receptor 0.0024 0.0025 0.0027
Plasmodium falciparum glutathione reductase 0.0901 0.2816 0.6061
Loa Loa (eye worm) hypothetical protein 0.0358 0.1088 0.2343
Trichomonas vaginalis conserved hypothetical protein 0.0027 0.0033 0.0071
Echinococcus granulosus pyruvate kinase 0.007 0.017 0.022
Brugia malayi Zinc finger protein 183 homolog 0.0027 0.0033 0.0072
Leishmania major serine peptidase, putative,serine peptidase, Clan SC, Family S9D 0.0087 0.0224 0.0795
Loa Loa (eye worm) hypothetical protein 0.0525 0.1619 0.3485
Trypanosoma cruzi hypothetical protein, conserved 0.0027 0.0033 0.0117
Echinococcus granulosus RING finger and transmembrane domain containing protein 0.0027 0.0033 0.0043
Echinococcus multilocularis Nuclear hormone receptor HR96 0.0024 0.0025 0.0032
Trichomonas vaginalis importin beta-1, putative 0.0024 0.0025 0.0054
Echinococcus granulosus cell growth regulator with ring finger domain 0.0027 0.0033 0.0043
Mycobacterium ulcerans NADPH:adrenodoxin oxidoreductase FprB 0.0083 0.0212 0.0191
Brugia malayi Importin beta-1 subunit 0.003 0.0043 0.0093
Echinococcus granulosus Nuclear hormone receptor HR96 0.0024 0.0025 0.0032
Leishmania major hypothetical protein, conserved 0.0083 0.0212 0.0752
Schistosoma mansoni rnf5 0.0027 0.0033 0.0036
Trichomonas vaginalis conserved hypothetical protein 0.0027 0.0033 0.0071
Plasmodium vivax trophozoite exported protein 1, putative 0.0027 0.0033 0.0071
Loa Loa (eye worm) nuclear hormone receptor 0.0111 0.0301 0.0648
Plasmodium falciparum AP endonuclease (DNA-[apurinic or apyrimidinic site] lyase), putative 0.0038 0.0069 0.0148
Echinococcus granulosus Smad4 0.0062 0.0144 0.0186
Trichomonas vaginalis Clan SC, family S33, methylesterase-like serine peptidase 0.0087 0.0224 0.0482
Chlamydia trachomatis pyruvate kinase 0.007 0.017 0.026
Toxoplasma gondii pyruvate kinase PyK1 0.007 0.017 0.0367
Echinococcus granulosus histone lysine methyltransferase setb 0.0031 0.0046 0.006
Toxoplasma gondii DNA topoisomerase domain-containing protein 0.1477 0.4646 1
Loa Loa (eye worm) nuclear hormone receptor family member nhr-41 0.0051 0.0111 0.024
Entamoeba histolytica Ran family GTPase 0.0022 0.0018 0.0207
Mycobacterium leprae Probable homoserine o-acetyltransferase MetA 0.0087 0.0224 0.0193
Brugia malayi brahma associated protein 60 kDa 0.1477 0.4646 1
Echinococcus granulosus pyruvate kinase 0.007 0.017 0.022
Entamoeba histolytica zinc finger domain containing protein 0.0027 0.0033 0.0376
Entamoeba histolytica HAD hydrolase, family IA, variant 3 0.0082 0.0208 0.2371
Schistosoma mansoni smad 0.0028 0.0036 0.0039
Giardia lamblia Hypothetical protein 0.0027 0.0033 0.016
Entamoeba histolytica pyridine nucleotide-disulfide oxidoreductase family protein 0.0083 0.0212 0.2413
Loa Loa (eye worm) jmjC domain-containing protein 0.0062 0.0146 0.0315
Brugia malayi Zn-finger in Ran binding protein and others containing protein 0.0525 0.1619 0.3485
Mycobacterium tuberculosis NADPH-dependent mycothiol reductase Mtr 0.0901 0.2816 0.2801
Giardia lamblia Protein 21.1 0.0027 0.0033 0.016
Plasmodium vivax multidomain scavenger receptor, putative 0.0017 0.0001 0.0003
Giardia lamblia Protein 21.1 0.0027 0.0033 0.016
Loa Loa (eye worm) hypothetical protein 0.018 0.0522 0.1123
Mycobacterium tuberculosis Protein tyrosine kinase transcriptional regulatory protein PtkA 0.0082 0.0208 0.0187
Trichomonas vaginalis 2-deoxyglucose-6-phosphate phosphatase, putative 0.0082 0.0208 0.0448
Trichomonas vaginalis dihydropyrimidine dehydrogenase, putative 0.0083 0.0212 0.0456
Loa Loa (eye worm) hypothetical protein 0.0102 0.0272 0.0585
Loa Loa (eye worm) HAD-superfamily hydrolase 0.0082 0.0208 0.0448
Brugia malayi Zn-finger in Ran binding protein and others containing protein 0.0525 0.1619 0.3485
Leishmania major hypothetical protein, conserved 0.0525 0.1619 0.575
Trypanosoma cruzi dihydrolipoyl dehydrogenase, putative 0.0312 0.0942 0.3344
Loa Loa (eye worm) hypothetical protein 0.0027 0.0033 0.0071
Loa Loa (eye worm) O-glycosyl hydrolase family 30 protein 0.0255 0.0761 0.1637
Brugia malayi MAP kinase sur-1 0.0058 0.0133 0.0287
Loa Loa (eye worm) hypothetical protein 0.0083 0.0212 0.0456
Leishmania major hypothetical protein, conserved 0.0027 0.0033 0.0117
Brugia malayi hypothetical protein 0.0494 0.1518 0.3268
Mycobacterium tuberculosis Probable NADPH dependent 2,4-dienoyl-CoA reductase FadH (2,4-dienoyl coenzyme A reductase) (4-enoyl-CoA reductase) 0.0083 0.0212 0.0191
Entamoeba histolytica hypothetical protein 0.0118 0.0324 0.3698
Toxoplasma gondii RING zinc finger protein 0.0027 0.0033 0.0071
Trichomonas vaginalis sex-determining protein fem-1, putative 0.0027 0.0033 0.0071
Trypanosoma brucei cysteine peptidase, Clan CA, family C54, putative 0.0025 0.0029 0.0039
Echinococcus multilocularis Nuclear pore complex protein Nup153 0.0525 0.1619 0.2092
Wolbachia endosymbiont of Brugia malayi thioredoxin reductase 0.0083 0.0212 0.1636
Echinococcus granulosus intermediate filament protein 0.0031 0.0046 0.0059
Onchocerca volvulus Pyruvate kinase homolog 0.007 0.017 0.0367
Loa Loa (eye worm) DnaJ domain-containing protein 0.0071 0.0173 0.0373
Schistosoma mansoni inhibitor of apoptosis 1 diap1 0.0027 0.0033 0.0036
Mycobacterium ulcerans epoxide hydrolase EphE 0.0087 0.0224 0.0203
Entamoeba histolytica exodeoxyribonuclease III, putative 0.0038 0.0069 0.0786
Loa Loa (eye worm) HAD-superfamily hydrolase 0.0082 0.0208 0.0448
Echinococcus multilocularis citrate lyase subunit beta protein 0.0023 0.0021 0.0027
Entamoeba histolytica HAD hydrolase, family IA, variant 3 0.0082 0.0208 0.2371
Echinococcus granulosus lysosomal alpha glucosidase 0.0139 0.039 0.0504
Echinococcus multilocularis Peptidase C54 0.0065 0.0156 0.0201
Loa Loa (eye worm) hypothetical protein 0.0077 0.0194 0.0418
Leishmania major hypothetical protein, conserved 0.0087 0.0224 0.0795
Schistosoma mansoni tar DNA-binding protein 0.0063 0.0147 0.0161
Echinococcus multilocularis RING finger and transmembrane domain containing protein 0.0027 0.0033 0.0043
Trypanosoma cruzi dihydrolipoamide dehydrogenase, putative 0.0312 0.0942 0.3344
Schistosoma mansoni hypothetical protein 0.0065 0.0153 0.0168
Toxoplasma gondii histone lysine acetyltransferase GCN5-A 0.0043 0.0083 0.018
Schistosoma mansoni Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) 0.0126 0.0347 0.0381
Plasmodium falciparum thioredoxin reductase 0.0312 0.0942 0.2027
Echinococcus multilocularis microtubule associated protein 2 0.227 0.7171 0.9265
Trypanosoma cruzi Ankyrin repeats (3 copies)/Zinc finger, C3HC4 type (RING finger), putative 0.0027 0.0033 0.0117
Trichomonas vaginalis Clan SC, family S33, methylesterase-like serine peptidase 0.0087 0.0224 0.0482
Schistosoma mansoni serine/threonine protein kinase 0.0027 0.0035 0.0038
Schistosoma mansoni retinoic acid receptor RXR 0.0051 0.0111 0.0122
Echinococcus granulosus E3 ubiquitin protein ligase LRSAM1 0.0027 0.0033 0.0043
Echinococcus multilocularis pyruvate kinase 0.0036 0.0062 0.008
Brugia malayi hydrolase, alpha/beta fold family protein 0.0087 0.0224 0.0482
Echinococcus multilocularis hepatocyte nuclear factor 4 alpha 0.0051 0.0111 0.0144
Schistosoma mansoni polycystin 1-related 0.0017 0.0001 0.0002
Loa Loa (eye worm) pyridine nucleotide-disufhide oxidoreductase 0.0083 0.0212 0.0456
Mycobacterium ulcerans pyruvate kinase 0.007 0.017 0.015
Loa Loa (eye worm) DR-78 0.0024 0.0025 0.0054
Trypanosoma cruzi glycosyl hydrolase, putative 0.0082 0.0208 0.0739
Onchocerca volvulus 0.0027 0.0033 0.0071
Echinococcus granulosus E3 ubiquitin protein ligase RNF146 0.0027 0.0033 0.0043
Schistosoma mansoni pyruvate kinase 0.0036 0.0062 0.0068
Onchocerca volvulus 0.0082 0.0208 0.0448
Mycobacterium leprae DIHYDROLIPOAMIDE DEHYDROGENASE LPD (LIPOAMIDE REDUCTASE (NADH)) (LIPOYL DEHYDROGENASE) (DIHYDROLIPOYL DEHYDROGENASE) (DIAPHORASE 0.2286 0.7221 1
Giardia lamblia Zinc finger domain 0.0027 0.0033 0.016
Schistosoma mansoni zinc finger protein 0.0024 0.0025 0.0027
Onchocerca volvulus 0.0041 0.0079 0.0169
Plasmodium vivax pyruvate kinase 2, putative 0.0036 0.0062 0.0134
Loa Loa (eye worm) hypothetical protein 0.0049 0.0103 0.0222
Echinococcus granulosus survival motor neuron protein 1 0.0202 0.0589 0.0761
Schistosoma mansoni disulfide oxidoreductase 0.0083 0.0212 0.0232
Echinococcus multilocularis Zinc finger, RanBP2 type 0.0525 0.1619 0.2092
Trypanosoma cruzi hypothetical protein 0.0027 0.0033 0.0117
Brugia malayi AMP-binding enzyme family protein 0.0043 0.0086 0.0185
Leishmania major cathepsin L-like protease 0.0062 0.0146 0.052
Brugia malayi Peptidase family C54 containing protein 0.0065 0.0156 0.0335
Brugia malayi HAD-superfamily hydrolase, subfamily IA, variant 1 containing protein 0.0082 0.0208 0.0448
Leishmania major 2-oxoglutarate dehydrogenase, e3 component, lipoamidedehydrogenase-like protein 0.0312 0.0942 0.3344
Trichomonas vaginalis Clan SC, family S33, methylesterase-like serine peptidase 0.0087 0.0224 0.0482
Entamoeba histolytica peptidase, C54 family 0.0025 0.0029 0.033
Mycobacterium tuberculosis Probable oxidoreductase 0.0087 0.0224 0.0203
Toxoplasma gondii GTP-binding nuclear protein ran/tc4 0.0022 0.0018 0.0039
Schistosoma mansoni alpha-glucosidase 0.012 0.0328 0.036
Echinococcus granulosus Upstream activation factor subunit UAF30 0.1477 0.4646 0.6003
Trichomonas vaginalis glucosylceramidase, putative 0.0168 0.0481 0.1036
Echinococcus granulosus PHD finger protein rhinoceros 0.003 0.0044 0.0057
Trichomonas vaginalis glucosylceramidase, putative 0.0168 0.0481 0.1036
Leishmania major hypothetical protein, conserved 0.0027 0.0033 0.0117
Echinococcus granulosus retinoic acid receptor rxr beta a 0.0051 0.0111 0.0144
Brugia malayi Nuclear hormone receptor-like 1 0.0027 0.0034 0.0074
Schistosoma mansoni smad1 5 8 and 0.0062 0.0144 0.0158
Brugia malayi O-Glycosyl hydrolase family 30 protein 0.0255 0.0761 0.1637
Trichomonas vaginalis glutamate synthase, putative 0.0083 0.0212 0.0456
Mycobacterium ulcerans exported protease 0.0087 0.0224 0.0203
Trypanosoma cruzi hypothetical protein, conserved 0.02 0.0583 0.207
Schistosoma mansoni jumonji domain containing protein 0.0079 0.0198 0.0217
Loa Loa (eye worm) hypothetical protein 0.0024 0.0025 0.0054
Trichomonas vaginalis conserved hypothetical protein 0.0027 0.0033 0.0071
Loa Loa (eye worm) pyruvate kinase 0.007 0.017 0.0367
Giardia lamblia Kinase, CMGC MAPK 0.0058 0.0133 0.1248
Toxoplasma gondii NADH dehydrogenase (NDH2-II) 0.0083 0.0212 0.0456
Leishmania major alpha glucosidase II subunit, putative 0.0031 0.0046 0.0163
Giardia lamblia Protein 21.1 0.0027 0.0033 0.016
Mycobacterium tuberculosis Probable thioredoxin reductase TrxB2 (TRXR) (TR) 0.0083 0.0212 0.0191
Echinococcus granulosus Nuclear pore complex protein Nup153 0.0525 0.1619 0.2092
Loa Loa (eye worm) RNA recognition domain-containing protein domain-containing protein 0.0063 0.0147 0.0317
Schistosoma mansoni nuclear receptor 2DBD-gamma 0.0051 0.0111 0.0122
Echinococcus multilocularis mothers against decapentaplegic 5 0.0062 0.0144 0.0186
Trichomonas vaginalis 2-deoxyglucose-6-phosphate phosphatase, putative 0.0082 0.0208 0.0448
Mycobacterium tuberculosis Probable fatty-acid-CoA ligase FadD3 (fatty-acid-CoA synthetase) (fatty-acid-CoA synthase) 0.0031 0.0046 0.0025
Echinococcus multilocularis pyruvate kinase 0.007 0.017 0.022
Echinococcus granulosus abhydrolase domain containing protein 11 0.0087 0.0224 0.0289
Brugia malayi Muscleblind-like protein 0.0149 0.0423 0.0911
Schistosoma mansoni hypothetical protein 0.0027 0.0033 0.0036
Onchocerca volvulus Glucosylceramidase homolog 0.0168 0.0481 0.1036
Entamoeba histolytica hypothetical protein 0.0024 0.0025 0.0288
Mycobacterium ulcerans homoserine O-acetyltransferase 0.0087 0.0224 0.0203
Brugia malayi Doublecortin family protein 0.0017 0.0001 0.0003
Trichomonas vaginalis protein kinase inhibitor, putative 0.0071 0.0173 0.0373
Echinococcus multilocularis nuclear receptor subfamily 4 group A 0.0024 0.0025 0.0032
Mycobacterium tuberculosis NAD(P)H quinone reductase LpdA 0.2286 0.7221 0.7215
Entamoeba histolytica haloacid dehalogenase-like hydrolase domain-containing protein 0.0082 0.0208 0.2371
Trichomonas vaginalis alpha-glucosidase, putative 0.0031 0.0046 0.0099
Echinococcus multilocularis lysine specific demethylase 5A 0.0037 0.0064 0.0083
Loa Loa (eye worm) hypothetical protein 0.0027 0.0033 0.0071
Echinococcus multilocularis lysosomal acid lipase:cholesteryl ester 0.0087 0.0224 0.0289
Brugia malayi glutamate synthase 0.0083 0.0212 0.0456
Trypanosoma brucei Zinc finger, C3HC4 type (RING finger), putative 0.0027 0.0033 0.0053
Onchocerca volvulus 0.0525 0.1619 0.3485
Schistosoma mansoni hypothetical protein 0.0065 0.0153 0.0168
Mycobacterium ulcerans non-heme haloperoxidase Hpx 0.0087 0.0224 0.0203
Schistosoma mansoni sulfide quinone reductase 0.0083 0.0212 0.0232
Echinococcus granulosus nuclear receptor 2DBD gamma 0.0024 0.0025 0.0032
Echinococcus multilocularis guanine nucleotide binding protein G(s) subunit 0.0126 0.0347 0.0449
Plasmodium falciparum dihydrolipoyl dehydrogenase, apicoplast 0.0312 0.0942 0.2027
Brugia malayi Nuclear hormone receptor family member nhr-40 0.0051 0.0111 0.024
Mycobacterium ulcerans hypothetical protein 0.0087 0.0224 0.0203
Plasmodium vivax thioredoxin reductase, putative 0.0901 0.2816 0.6061
Brugia malayi Niemann-Pick C1 protein precursor 0.018 0.0522 0.1123
Echinococcus multilocularis cysteine protease atg4b 0.0065 0.0156 0.0201
Trypanosoma brucei pyruvate kinase 1 0.007 0.017 0.0544
Echinococcus multilocularis GTP binding nuclear protein Ran 0.0022 0.0018 0.0023
Plasmodium falciparum type II NADH:ubiquinone oxidoreductase 0.0083 0.0212 0.0456
Mycobacterium leprae PROBABLE NADH DEHYDROGENASE NDH 0.2056 0.6491 0.8977
Mycobacterium tuberculosis Probable oxidoreductase 0.2286 0.7221 0.7215
Echinococcus granulosus Nuclear hormone receptor family member nhr 41 0.0051 0.0111 0.0144
Brugia malayi MH2 domain containing protein 0.0062 0.0144 0.031
Leishmania major 4-coumarate:coa ligase-like protein 0.0043 0.0086 0.0306
Mycobacterium tuberculosis Probable reductase 0.2056 0.6491 0.6483
Toxoplasma gondii pyruvate kinase PyKII 0.0036 0.0062 0.0134
Loa Loa (eye worm) nuclear hormone receptor family member nhr-49 0.0051 0.0111 0.024
Trichomonas vaginalis 2-deoxyglucose-6-phosphate phosphatase, putative 0.0082 0.0208 0.0448
Schistosoma mansoni histone-lysine n-methyltransferase suv9 0.0031 0.0046 0.0051
Trichomonas vaginalis fructose-bisphosphate aldolase, putative 0.0292 0.0878 0.1889
Brugia malayi Thioredoxin reductase 0.0901 0.2816 0.6061
Brugia malayi MH1 domain containing protein 0.0034 0.0056 0.0121
Toxoplasma gondii hypothetical protein 0.0027 0.0033 0.0071
Trichomonas vaginalis ankyrin repeat-containing protein, putative 0.0027 0.0033 0.0071
Echinococcus granulosus lamin 0.0031 0.0046 0.0059
Entamoeba histolytica peptidase, C54 family 0.0065 0.0156 0.1774
Entamoeba histolytica Niemann-Pick C1 protein, putative 0.018 0.0522 0.5945
Trichomonas vaginalis conserved hypothetical protein 0.0027 0.0033 0.0071
Echinococcus multilocularis SWI:SNF matrix associated 0.1477 0.4646 0.6003
Trichomonas vaginalis conserved hypothetical protein 0.0027 0.0033 0.0071
Echinococcus granulosus zinc finger protein Ran binding 0.0525 0.1619 0.2092
Echinococcus granulosus haloacid dehalogenase hydrolase 0.0082 0.0208 0.0269
Plasmodium falciparum NAD(P)H-dependent glutamate synthase, putative 0.0083 0.0212 0.0456
Toxoplasma gondii histone lysine methyltransferase SET/SUV39 0.0031 0.0046 0.01
Loa Loa (eye worm) hypothetical protein 0.0104 0.028 0.0603
Trypanosoma brucei Zinc finger, C3HC4 type (RING finger), putative 0.0027 0.0033 0.0053
Loa Loa (eye worm) HAD-superfamily hydrolase 0.0082 0.0208 0.0448
Trichomonas vaginalis 2-deoxyglucose-6-phosphate phosphatase, putative 0.0082 0.0208 0.0448
Loa Loa (eye worm) hypothetical protein 0.0027 0.0033 0.0071
Loa Loa (eye worm) MH2 domain-containing protein 0.0905 0.2828 0.6086
Loa Loa (eye worm) hypothetical protein 0.0031 0.0046 0.0099
Echinococcus multilocularis nuclear receptor subfamily 1 group D 0.0027 0.0034 0.0044
Trypanosoma brucei Zinc finger, C3HC4 type (RING finger), putative 0.0027 0.0033 0.0053
Loa Loa (eye worm) hypothetical protein 0.0032 0.0051 0.011
Loa Loa (eye worm) hypothetical protein 0.0024 0.0025 0.0054
Echinococcus multilocularis mothers against decapentaplegic 2 0.0028 0.0036 0.0046
Chlamydia trachomatis SWIB complex protein 0.1477 0.4646 1
Loa Loa (eye worm) hypothetical protein 0.0095 0.025 0.0537
Brugia malayi Pre-SET motif family protein 0.0215 0.0633 0.1363
Giardia lamblia Ser/Thr protein kinase 0.0027 0.0033 0.016
Brugia malayi hydrolase, alpha/beta fold family protein 0.0087 0.0224 0.0482
Brugia malayi Nuclear hormone receptor E75 0.0024 0.0025 0.0054
Schistosoma mansoni hypothetical protein 0.0083 0.0212 0.0232
Entamoeba histolytica hypothetical protein 0.0027 0.0033 0.0376
Onchocerca volvulus 0.0027 0.0033 0.0071
Trichomonas vaginalis 2-deoxyglucose-6-phosphate phosphatase, putative 0.0082 0.0208 0.0448
Trypanosoma cruzi UEV domain/Zinc finger, C3HC4 type (RING finger), putative 0.0027 0.0033 0.0117
Onchocerca volvulus Alhambra homolog 0.003 0.0044 0.0095
Schistosoma mansoni RAR-like nuclear receptor 0.0051 0.0111 0.0122
Trypanosoma brucei glucosidase, putative 0.0031 0.0046 0.0099
Echinococcus multilocularis Basic leucine zipper (bZIP) transcription 0.0118 0.0324 0.0419
Leishmania major 4-coumarate:coa ligase-like protein 0.0043 0.0086 0.0306
Echinococcus multilocularis tumor protein p63 0.2449 0.774 1
Trichomonas vaginalis CMGC family protein kinase 0.0058 0.0133 0.0287
Trypanosoma cruzi mitogen activated protein kinase 2, putative 0.0058 0.0133 0.0474
Mycobacterium tuberculosis Probable exported protease 0.0087 0.0224 0.0203
Echinococcus granulosus importin subunit beta 1 0.003 0.0043 0.0056
Onchocerca volvulus 0.0024 0.0025 0.0054
Leishmania major hypothetical protein, conserved 0.0027 0.0033 0.0117
Toxoplasma gondii Bardet-Biedl syndrome 5, putative 0.0027 0.0033 0.0071
Trichomonas vaginalis fructose-bisphosphate aldolase, putative 0.0292 0.0878 0.1889
Echinococcus multilocularis abhydrolase domain containing 3 0.0087 0.0224 0.0289
Trichomonas vaginalis ankyrin, putative 0.0027 0.0033 0.0071
Giardia lamblia Histone acetyltransferase GCN5 0.0039 0.0072 0.0585
Trypanosoma cruzi hypothetical protein, conserved 0.0083 0.0212 0.0752
Mycobacterium ulcerans hypothetical protein 0.0087 0.0224 0.0203
Onchocerca volvulus Nuclear receptor subfamily 6 group A member 1 homolog 0.0024 0.0025 0.0054
Echinococcus granulosus dnaJ subfamily C 6 0.0071 0.0173 0.0224
Echinococcus multilocularis E3 ubiquitin protein ligase mib1 0.0027 0.0033 0.0043
Giardia lamblia Glycerol-3-phosphate dehydrogenase 0.0083 0.0212 0.2096
Echinococcus multilocularis pyridine nucleotide disulfide oxidoreductase 0.0083 0.0212 0.0274
Mycobacterium leprae Probable fructose bisphosphate aldolase Fba 0.0143 0.0402 0.0443
Trypanosoma brucei pyridine nucleotide-disulphide oxidoreductase, putative 0.0083 0.0212 0.0692
Leishmania major hypothetical protein, conserved 0.0027 0.0033 0.0117
Loa Loa (eye worm) PHD-finger family protein 0.003 0.0044 0.0095
Echinococcus multilocularis diuretic hormone 44 receptor GPRdih2 0.0065 0.0153 0.0198
Echinococcus multilocularis musashi 0.0031 0.0046 0.0059
Loa Loa (eye worm) glutaminase 0.0292 0.0878 0.1889
Giardia lamblia Endonuclease/Exonuclease/phosphatase 0.0038 0.0069 0.055
Schistosoma mansoni smad1 5 8 and 0.0062 0.0144 0.0158
Trypanosoma cruzi hypothetical protein, conserved 0.0525 0.1619 0.575
Loa Loa (eye worm) MH2 domain-containing protein 0.0062 0.0144 0.031
Plasmodium vivax RING zinc finger protein, putative 0.0027 0.0033 0.0071
Leishmania major hypothetical protein, conserved 0.0027 0.0033 0.0117
Echinococcus multilocularis pyruvate kinase 0.0036 0.0062 0.008
Trypanosoma cruzi GTP-binding nuclear protein rtb2, putative 0.0022 0.0018 0.0064
Schistosoma mansoni thyroid hormone receptor 0.0051 0.0111 0.0122
Giardia lamblia Protein 21.1 0.0027 0.0033 0.016
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0062 0.0146 0.0458
Brugia malayi MH1 domain containing protein 0.0062 0.0144 0.031
Trypanosoma cruzi Plus-3 domain/Zinc finger, C3HC4 type (RING finger), putative 0.0027 0.0033 0.0117
Trichomonas vaginalis fructose-bisphosphate aldolase, putative 0.0292 0.0878 0.1889
Loa Loa (eye worm) hypothetical protein 0.0043 0.0086 0.0185
Echinococcus multilocularis nuclear receptor nhr 48 0.0024 0.0025 0.0032
Trypanosoma cruzi mitochondrial RNA binding complex 1 subunit, putative 0.0525 0.1619 0.575
Trichomonas vaginalis ap endonuclease, putative 0.0038 0.0069 0.0148
Schistosoma mansoni peter pan-related 0.0027 0.0033 0.0036
Mycobacterium tuberculosis Probable NADH-dependent glutamate synthase (small subunit) GltD (L-glutamate synthase) (L-glutamate synthetase) (NADH-glutamate 0.0083 0.0212 0.0191
Loa Loa (eye worm) MH1 domain-containing protein 0.0062 0.0144 0.031
Brugia malayi Bromodomain containing protein 0.0034 0.0055 0.0119
Mycobacterium ulcerans dihydrolipoamide dehydrogenase 0.0312 0.0942 0.0923
Brugia malayi steroid hormone receptor 0.0051 0.0111 0.024
Echinococcus multilocularis thioredoxin glutathione reductase 0.0911 0.2846 0.3677
Trichomonas vaginalis fructose-bisphosphate aldolase, putative 0.0292 0.0878 0.1889
Plasmodium falciparum alpha/beta hydrolase, putative 0.0087 0.0224 0.0482
Loa Loa (eye worm) hypothetical protein 0.0525 0.1619 0.3485
Trichomonas vaginalis cell cycle control protein cwf24, putative 0.0027 0.0033 0.0072
Schistosoma mansoni ring finger protein 151 0.0027 0.0033 0.0036
Trichomonas vaginalis disulfide oxidoreductase, putative 0.0083 0.0212 0.0456
Onchocerca volvulus Nuclear receptor subfamily 6 group A member 1 homolog 0.0024 0.0025 0.0054
Schistosoma mansoni lamin 0.0031 0.0046 0.005
Plasmodium falciparum acyl-CoA synthetase 0.0032 0.0051 0.011
Schistosoma mansoni importin beta-1 0.003 0.0043 0.0047
Wolbachia endosymbiont of Brugia malayi dihydrolipoamide dehydrogenase E3 component 0.0312 0.0942 1
Trypanosoma cruzi dihydrolipoamide dehydrogenase, putative 0.0312 0.0942 0.3344
Brugia malayi RING zinc finger protein 0.0027 0.0033 0.0071
Echinococcus granulosus muscleblind protein 0.0149 0.0423 0.0547
Echinococcus multilocularis ring finger protein 113a 0.0027 0.0033 0.0043
Echinococcus granulosus thyroid hormone receptor alpha 0.0024 0.0025 0.0032
Echinococcus granulosus guanine nucleotide binding protein Gs subunit 0.0126 0.0347 0.0449
Schistosoma mansoni jumonji/arid domain-containing protein 0.0037 0.0064 0.007
Echinococcus granulosus FTZ F1 alpha 0.0051 0.0111 0.0144
Brugia malayi intermediate filament protein 0.0031 0.0046 0.0099
Echinococcus multilocularis abhydrolase domain containing protein 3 0.0087 0.0224 0.0289
Toxoplasma gondii SWI2/SNF2-containing protein RAD5 0.0027 0.0033 0.0071
Brugia malayi hypothetical protein 0.0027 0.0033 0.0071
Echinococcus granulosus lipoxygenase domain containing protein 0.0017 0.0001 0.0002
Mycobacterium ulcerans hypothetical protein 0.0087 0.0224 0.0203
Loa Loa (eye worm) hypothetical protein 0.0051 0.0111 0.024
Giardia lamblia Hypothetical protein 0.0027 0.0033 0.016
Mycobacterium ulcerans acyl-CoA synthetase 0.0043 0.0086 0.0065
Plasmodium falciparum zinc finger protein, putative 0.0027 0.0033 0.0071
Mycobacterium ulcerans haloalkane dehalogenase 0.0087 0.0224 0.0203
Brugia malayi Hypothetical 54.7 kDa protein F37A4.1 in chromosome III 0.0087 0.0224 0.0482
Schistosoma mansoni loxhd1 0.0017 0.0001 0.0002
Entamoeba histolytica zinc finger domain containing protein 0.0027 0.0033 0.0376
Echinococcus multilocularis expressed conserved protein 0.0169 0.0487 0.0629
Schistosoma mansoni hypothetical protein 0.0164 0.047 0.0515
Leishmania major hypothetical protein, conserved 0.0083 0.0212 0.0752
Schistosoma mansoni smad1 5 8 and 0.0062 0.0144 0.0158
Trypanosoma brucei trypanothione reductase 0.0901 0.2816 1
Trypanosoma cruzi NADPH:adrenodoxin oxidoreductase, mitochondrial, putative 0.0083 0.0212 0.0752
Loa Loa (eye worm) hypothetical protein 0.0032 0.0051 0.011
Echinococcus granulosus citrate lyase subunit beta protein 0.0023 0.0021 0.0027
Trichomonas vaginalis fructose-bisphosphate aldolase, putative 0.0292 0.0878 0.1889
Trypanosoma brucei hypothetical protein, conserved 0.02 0.0583 0.2019
Brugia malayi Nuclear hormone receptor family member nhr-3 0.0051 0.0111 0.024
Loa Loa (eye worm) brahma associated protein 0.1477 0.4646 1
Trypanosoma cruzi AUT2/APG4/ATG4 cysteine peptidase, putative 0.0025 0.0029 0.0103
Brugia malayi jmjC domain containing protein 0.0037 0.0064 0.0138
Echinococcus multilocularis Upstream activation factor subunit UAF30 0.1477 0.4646 0.6003
Onchocerca volvulus Epoxide hydrolase 1 homolog 0.0087 0.0224 0.0482
Echinococcus multilocularis muscleblind protein 1 0.0149 0.0423 0.0547
Entamoeba histolytica zinc finger domain containing protein 0.0027 0.0033 0.0376
Wolbachia endosymbiont of Brugia malayi phosphatase 0.0082 0.0208 0.1593
Onchocerca volvulus 0.0017 0.0001 0.0003
Entamoeba histolytica peptidase, C54 family 0.0025 0.0029 0.033
Brugia malayi calcium-independent alpha-latrotoxin receptor 2, putative 0.0065 0.0153 0.033
Entamoeba histolytica HAD hydrolase, family IA, variant 3 0.0082 0.0208 0.2371
Trypanosoma brucei dihydrolipoamide dehydrogenase, point mutation 0.0312 0.0942 0.3301
Loa Loa (eye worm) hypothetical protein 0.0204 0.0597 0.1285
Trichomonas vaginalis pyruvate kinase, putative 0.007 0.017 0.0367
Mycobacterium tuberculosis Possible short-chain dehydrogenase EphD 0.0087 0.0224 0.0203
Echinococcus granulosus microtubule associated protein 2 0.227 0.7171 0.9265
Echinococcus granulosus nuclear receptor 2DBD gamma 0.0051 0.0111 0.0144
Trichomonas vaginalis conserved hypothetical protein 0.0027 0.0033 0.0071
Loa Loa (eye worm) nuclear Hormone Receptor family member 0.0051 0.0111 0.024
Trypanosoma cruzi hypothetical protein 0.0027 0.0033 0.0117
Mycobacterium ulcerans hypothetical protein 0.0082 0.0208 0.0187
Plasmodium vivax E3 ubiquitin-protein ligase, putative 0.0027 0.0033 0.0071
Plasmodium falciparum phd finger protein, putative 0.003 0.0044 0.0095
Giardia lamblia Kinase 0.0027 0.0035 0.0179
Entamoeba histolytica zinc finger domain containing protein 0.0027 0.0033 0.0376
Loa Loa (eye worm) hypothetical protein 0.007 0.017 0.0367
Toxoplasma gondii non-proton pumping type-II NADH dehydrogenase I 0.0083 0.0212 0.0456
Brugia malayi nuclear receptor RXR 0.0024 0.0025 0.0054
Plasmodium vivax hypothetical protein, conserved 0.0087 0.0224 0.0482
Trichomonas vaginalis disulfide oxidoreductase, putative 0.0083 0.0212 0.0456
Mycobacterium ulcerans dihydrolipoamide dehydrogenase, LpdB 0.0312 0.0942 0.0923
Trichomonas vaginalis conserved hypothetical protein 0.0027 0.0033 0.0071
Giardia lamblia Protein 21.1 0.0027 0.0033 0.016
Onchocerca volvulus 0.008 0.0203 0.0438
Trypanosoma cruzi hypothetical protein, conserved 0.0083 0.0212 0.0752
Mycobacterium ulcerans epoxide hydrolase EphF 0.0087 0.0224 0.0203
Trichomonas vaginalis maltase-glucoamylase, putative 0.0031 0.0046 0.0099
Brugia malayi Nuclear hormone receptor family member nhr-14 0.0051 0.0111 0.024
Plasmodium vivax histone acetyltransferase GCN5, putative 0.0043 0.0083 0.018
Schistosoma mansoni histone-lysine n-methyltransferase setb1 0.0031 0.0046 0.0051
Brugia malayi Phospholipase A2 family protein 0.0102 0.0272 0.0585
Mycobacterium tuberculosis Possible haloalkane dehalogenase DhaA (1-chlorohexane halidohydrolase) 0.0087 0.0224 0.0203
Plasmodium falciparum E3 ubiquitin-protein ligase RNF5, putative 0.0027 0.0033 0.0071
Loa Loa (eye worm) hypothetical protein 0.0525 0.1619 0.3485
Loa Loa (eye worm) HAD-superfamily hydrolase 0.0082 0.0208 0.0448
Trypanosoma cruzi importin beta-1 subunit, putative 0.0024 0.0025 0.009
Mycobacterium leprae Probable exported protease 0.0087 0.0224 0.0193
Echinococcus granulosus tar DNA binding protein 0.0063 0.0147 0.019
Trypanosoma cruzi NADH dehydrogenase, putative 0.0083 0.0212 0.0752
Giardia lamblia NADH oxidase lateral transfer candidate 0.0312 0.0942 1
Echinococcus granulosus ring finger protein 113a 0.0027 0.0033 0.0043
Onchocerca volvulus 0.0031 0.0046 0.0099
Trypanosoma cruzi hypothetical protein, conserved 0.0027 0.0033 0.0117
Loa Loa (eye worm) nuclear hormone receptor family member nhr-40 0.0051 0.0111 0.024
Brugia malayi brahma associated protein 60 kDa 0.1477 0.4646 1
Schistosoma mansoni hypothetical protein 0.0075 0.0185 0.0203
Trypanosoma cruzi trypanothione reductase, putative 0.0312 0.0942 0.3344
Trichomonas vaginalis ubiquitin-protein ligase BRE1, putative 0.0027 0.0033 0.0071
Trichomonas vaginalis 2-deoxyglucose-6-phosphate phosphatase, putative 0.0082 0.0208 0.0448
Mycobacterium leprae Probable NADH-dependent glutamate synthase (small subunit) GltD (L-glutamate synthase) (L-glutamate synthetase) (NADH-glutamate 0.0083 0.0212 0.0176
Echinococcus granulosus pyruvate kinase 0.0036 0.0062 0.008
Loa Loa (eye worm) GTP-binding regulatory protein Gs alpha-S chain 0.0126 0.0347 0.0748
Loa Loa (eye worm) hypothetical protein 0.0024 0.0025 0.0054
Schistosoma mansoni hypothetical protein 0.0075 0.0185 0.0203
Giardia lamblia PHD finger protein 15 0.003 0.0044 0.0279
Schistosoma mansoni gcn5proteinral control of amino-acid synthesis 5-like 2 gcnl2 0.0145 0.0409 0.0448
Brugia malayi Zn-finger in Ran binding protein and others containing protein 0.0525 0.1619 0.3485
Echinococcus multilocularis sterol regulatory element binding protein 0.0077 0.0194 0.0251
Entamoeba histolytica disulphide oxidoreductase, putative 0.0083 0.0212 0.2413
Loa Loa (eye worm) hypothetical protein 0.0051 0.0111 0.024
Echinococcus multilocularis dnaJ subfamily C 6 0.0071 0.0173 0.0224
Onchocerca volvulus 0.0494 0.1518 0.3268
Trichomonas vaginalis conserved hypothetical protein 0.0027 0.0033 0.0071
Brugia malayi alpha/beta hydrolase 0.0087 0.0224 0.0482
Giardia lamblia Hypothetical protein 0.0027 0.0033 0.016
Loa Loa (eye worm) hypothetical protein 0.0202 0.0589 0.1268
Trypanosoma cruzi mitochondrial RNA binding complex 1 subunit, putative 0.0525 0.1619 0.575
Schistosoma mansoni hypothetical protein 0.032 0.0966 0.1059
Schistosoma mansoni brg-1 associated factor 0.1477 0.4646 0.5092
Loa Loa (eye worm) pre-SET domain-containing protein family protein 0.0215 0.0633 0.1363
Brugia malayi HAD-superfamily hydrolase, subfamily IA, variant 3 containing protein 0.0082 0.0208 0.0448
Mycobacterium ulcerans ferredoxin reductase 0.0083 0.0212 0.0191
Leishmania major hypothetical protein, conserved 0.0027 0.0033 0.0117
Plasmodium falciparum zinc finger Ran-binding domain-containing protein 2, putative 0.0525 0.1619 0.3485
Trypanosoma cruzi mitogen activated protein kinase 4, putative 0.0058 0.0133 0.0474
Schistosoma mansoni hypothetical protein 0.0027 0.0033 0.0036
Mycobacterium ulcerans NADPH:adrenodoxin oxidoreductase FprA 0.0083 0.0212 0.0191
Schistosoma mansoni intermediate filament proteins 0.0031 0.0046 0.005
Trichomonas vaginalis conserved hypothetical protein 0.0027 0.0033 0.0071
Mycobacterium tuberculosis Probable fatty-acid-CoA ligase FadD7 (fatty-acid-CoA synthetase) (fatty-acid-CoA synthase) 0.0031 0.0046 0.0025
Onchocerca volvulus 0.0027 0.0033 0.0071
Schistosoma mansoni photoreceptor-specific nuclear receptor related 0.0051 0.0111 0.0122
Brugia malayi Nuclear hormone receptor family member nhr-49 0.0051 0.0111 0.024
Schistosoma mansoni hypothetical protein 0.0525 0.1619 0.1774
Loa Loa (eye worm) hypothetical protein 0.0087 0.0224 0.0482
Trichomonas vaginalis 2-deoxyglucose-6-phosphate phosphatase, putative 0.0082 0.0208 0.0448
Schistosoma mansoni hypothetical protein 0.0027 0.0033 0.0036
Echinococcus multilocularis mitogen activated protein kinase 3 0.0058 0.0133 0.0172
Giardia lamblia Pyruvate kinase 0.0036 0.0062 0.0476
Plasmodium vivax GTP-binding nuclear protein RAN/TC4, putative 0.0022 0.0018 0.0039
Echinococcus multilocularis E3 ubiquitin protein ligase LRSAM1 0.0027 0.0033 0.0043
Brugia malayi acetyltransferase, GNAT family protein 0.0145 0.0409 0.088
Trypanosoma cruzi WLM domain containing protein, putative 0.0525 0.1619 0.575
Mycobacterium tuberculosis NADPH:adrenodoxin oxidoreductase FprA (NADPH-ferredoxin reductase) 0.0083 0.0212 0.0191
Entamoeba histolytica alpha/beta hydrolase domain protein, putative 0.0087 0.0224 0.2552
Onchocerca volvulus 0.0027 0.0033 0.0071
Trichomonas vaginalis disulfide oxidoreductase, putative 0.0083 0.0212 0.0456
Echinococcus granulosus E3 ubiquitin protein ligase MYLIP 0.0027 0.0033 0.0043
Toxoplasma gondii thioredoxin reductase 0.0901 0.2816 0.6061
Brugia malayi nuclear receptor NHR-67 0.0024 0.0025 0.0054
Schistosoma mansoni thyroid hormone receptor 0.0051 0.0111 0.0122
Plasmodium vivax DNA repair protein RAD5, putative 0.0027 0.0033 0.0071
Brugia malayi hypothetical protein 0.0027 0.0033 0.0071
Loa Loa (eye worm) hypothetical protein 0.0104 0.028 0.0603
Entamoeba histolytica glutamate synthase beta subunit, putative 0.0083 0.0212 0.2413
Onchocerca volvulus Huntingtin homolog 0.0104 0.028 0.0603
Entamoeba histolytica hypothetical protein 0.0082 0.0208 0.2371
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0062 0.0146 0.0458
Schistosoma mansoni family C54 unassigned peptidase (C54 family) 0.0065 0.0156 0.0171
Echinococcus granulosus histone acetyltransferase KAT2B 0.0043 0.0083 0.0108
Echinococcus multilocularis gcn5proteinral control of amino acid synthesis 0.0145 0.0409 0.0528
Echinococcus granulosus apoptosis inducing factor 1 mitochondrial 0.0083 0.0212 0.0274
Giardia lamblia Pyruvate kinase 0.007 0.017 0.1648
Schistosoma mansoni niemann-pick C1 (NPC1) 0.0183 0.0531 0.0581
Brugia malayi NADPH:adrenodoxin oxidoreductase, mitochondrial precursor 0.0083 0.0212 0.0456
Schistosoma mansoni Smad4 0.0028 0.0036 0.0039
Trichomonas vaginalis conserved hypothetical protein 0.0082 0.0208 0.0448
Giardia lamblia Protein 21.1 0.0027 0.0033 0.016
Toxoplasma gondii HEAT repeat-containing protein 0.003 0.0043 0.0093
Plasmodium falciparum pyruvate kinase 2 0.0036 0.0062 0.0134
Mycobacterium tuberculosis Conserved hypothetical protein 0.0082 0.0208 0.0187
Entamoeba histolytica zinc finger domain containing protein 0.0027 0.0033 0.0376
Mycobacterium ulcerans NADH dehydrogenase Ndh 0.0083 0.0212 0.0191
Brugia malayi Glycosyl hydrolases family 31 protein 0.0031 0.0046 0.0099
Brugia malayi haloacid dehalogenase-like hydrolase family protein 0.0082 0.0208 0.0448
Brugia malayi Zn-finger in Ran binding protein and others containing protein 0.0525 0.1619 0.3485
Mycobacterium tuberculosis Possible epoxide hydrolase EphE (epoxide hydratase) (arene-oxide hydratase) 0.0087 0.0224 0.0203
Plasmodium falciparum SWIB/MDM2 domain-containing protein 0.1477 0.4646 1
Plasmodium vivax dihydrolipoyl dehydrogenase, mitochondrial, putative 0.0312 0.0942 0.2027
Leishmania major hypothetical protein, conserved 0.0027 0.0033 0.0117
Echinococcus multilocularis pyruvate kinase 0.0055 0.0124 0.016
Trichomonas vaginalis 2-deoxyglucose-6-phosphate phosphatase, putative 0.0082 0.0208 0.0448
Schistosoma mansoni hypothetical protein 0.0041 0.0079 0.0086
Trichomonas vaginalis sucrase-isomaltase, putative 0.0031 0.0046 0.0099
Loa Loa (eye worm) hypothetical protein 0.0027 0.0034 0.0074
Trichomonas vaginalis conserved hypothetical protein 0.0027 0.0033 0.0071
Loa Loa (eye worm) hypothetical protein 0.0027 0.0034 0.0074
Brugia malayi ecdysteroid receptor 0.0051 0.0111 0.024
Brugia malayi Ligand-binding domain of nuclear hormone receptor family protein 0.0051 0.0111 0.024
Brugia malayi nuclear hormone receptor family member odr-7 0.0024 0.0025 0.0054
Treponema pallidum NADH oxidase 0.0312 0.0942 1
Entamoeba histolytica hypothetical protein 0.0082 0.0208 0.2371
Leishmania major dihydrolipoamide dehydrogenase, putative 0.0312 0.0942 0.3344
Loa Loa (eye worm) hypothetical protein 0.0027 0.0034 0.0074
Trypanosoma cruzi major cysteine proteinase, putative 0.0049 0.0104 0.0369
Trypanosoma brucei mitochondrial RNA binding complex 1 subunit 0.0525 0.1619 0.5722
Leishmania major hypothetical protein, conserved 0.0525 0.1619 0.575
Echinococcus multilocularis apoptosis inducing factor 1 mitochondrial 0.0083 0.0212 0.0274
Brugia malayi RNA binding protein 0.0063 0.0147 0.0317
Leishmania major cathepsin L-like protease 0.0062 0.0146 0.052
Giardia lamblia Protein 21.1 0.0027 0.0033 0.016
Trichomonas vaginalis conserved hypothetical protein 0.0082 0.0208 0.0448
Giardia lamblia Protein 21.1 0.0027 0.0033 0.016
Entamoeba histolytica haloacid dehalogenase-like hydrolase domain-containing protein 0.0082 0.0208 0.2371
Trypanosoma cruzi UEV domain/Zinc finger, C3HC4 type (RING finger), putative 0.0027 0.0033 0.0117
Echinococcus granulosus GTP binding nuclear protein Ran 0.0022 0.0018 0.0023
Loa Loa (eye worm) hypothetical protein 0.0024 0.0025 0.0054
Mycobacterium ulcerans short chain dehydrogenase 0.0087 0.0224 0.0203
Echinococcus multilocularis tar DNA binding protein 0.0063 0.0147 0.019
Trichomonas vaginalis disulfide oxidoreductase, putative 0.0083 0.0212 0.0456
Trypanosoma cruzi pyruvate kinase 2, putative 0.007 0.017 0.0605
Trichomonas vaginalis glucosylceramidase, putative 0.0168 0.0481 0.1036
Toxoplasma gondii homoserine O-acetyltransferase, putative 0.0087 0.0224 0.0482
Loa Loa (eye worm) glutathione reductase 0.0901 0.2816 0.6061
Giardia lamblia Protein 21.1 0.0027 0.0033 0.016
Entamoeba histolytica glycosyl hydrolase, family 31 protein 0.0031 0.0046 0.0524
Trichomonas vaginalis conserved hypothetical protein 0.0027 0.0033 0.0071
Plasmodium vivax SWIB/MDM2 domain-containing protein, putative 0.1477 0.4646 1
Trichomonas vaginalis alpha-glucosidase, putative 0.0031 0.0046 0.0099
Echinococcus multilocularis lysosomal alpha glucosidase 0.0139 0.039 0.0504
Trichomonas vaginalis 2-deoxyglucose-6-phosphate phosphatase, putative 0.0082 0.0208 0.0448
Trichomonas vaginalis Clan SC, family S33, methylesterase-like serine peptidase 0.0087 0.0224 0.0482
Trypanosoma brucei NADH dehydrogenase 0.0083 0.0212 0.0692
Mycobacterium ulcerans hypothetical protein 0.0083 0.0212 0.0191
Leishmania major hypothetical protein, conserved 0.0027 0.0033 0.0117
Echinococcus granulosus FTZ F1 nuclear receptor protein 0.0051 0.0111 0.0144
Echinococcus granulosus haloacid dehalogenase hydrolase 0.0082 0.0208 0.0269
Trypanosoma cruzi UEV domain/Zinc finger, C3HC4 type (RING finger), putative 0.0027 0.0033 0.0117
Trypanosoma brucei hydrolase, alpha/beta fold family, putative 0.0087 0.0224 0.0735
Echinococcus multilocularis haloacid dehalogenase hydrolase 0.0082 0.0208 0.0269
Trypanosoma cruzi cysteine peptidase, clan CA, family C1, cathepsin L-like, putative 0.0057 0.0129 0.0458
Brugia malayi tailless protein 0.0024 0.0025 0.0054
Brugia malayi CHE-14 protein 0.0077 0.0194 0.0418
Echinococcus multilocularis TGF beta signal transducer SmadC 0.0062 0.0144 0.0186
Trypanosoma brucei Zinc finger, C3HC4 type (RING finger) containing protein, putative 0.0027 0.0033 0.0053
Trypanosoma brucei 2,4-dienoyl-coa reductase-like protein 0.0083 0.0212 0.0692
Trypanosoma cruzi hydrolase-like protein 0.0087 0.0224 0.0795
Schistosoma mansoni Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) 0.0126 0.0347 0.0381
Leishmania major hydrolase-like protein 0.0087 0.0224 0.0795
Loa Loa (eye worm) hypothetical protein 0.0043 0.0086 0.0185
Echinococcus multilocularis Polycystic kidney disease protein 0.0017 0.0001 0.0002
Trichomonas vaginalis conserved hypothetical protein 0.0027 0.0033 0.0071
Echinococcus multilocularis NADPH:adrenodoxin oxidoreductase 0.0083 0.0212 0.0274
Loa Loa (eye worm) transcription factor SMAD2 0.0905 0.2828 0.6086
Leishmania major hypothetical protein, conserved 0.0525 0.1619 0.575
Trypanosoma brucei Ankyrin repeats (3 copies)/Zinc finger, C3HC4 type (RING finger), putative 0.0027 0.0033 0.0053
Brugia malayi nuclear receptor NHR-88 0.0051 0.0111 0.024
Brugia malayi hypothetical protein 0.0024 0.0025 0.0054
Loa Loa (eye worm) hypothetical protein 0.0051 0.0111 0.024
Trichomonas vaginalis ion channel nompc, putative 0.0027 0.0033 0.0071
Brugia malayi latrophilin 2 splice variant baaae 0.0139 0.0392 0.0843
Giardia lamblia Protein 21.1 0.0027 0.0033 0.016
Trichomonas vaginalis glutaminase, putative 0.0292 0.0878 0.1889
Entamoeba histolytica acyl-CoA synthetase, putative 0.0043 0.0086 0.0981
Trichomonas vaginalis conserved hypothetical protein 0.0082 0.0208 0.0448
Plasmodium vivax E3 ubiquitin-protein ligase RNF5, putative 0.0027 0.0033 0.0071
Loa Loa (eye worm) hypothetical protein 0.0024 0.0025 0.0054
Schistosoma mansoni serine/threonine protein kinase 0.0058 0.0133 0.0146
Trichomonas vaginalis conserved hypothetical protein 0.0027 0.0033 0.0071
Echinococcus multilocularis abhydrolase domain containing protein 16A 0.0087 0.0224 0.0289
Echinococcus granulosus cysteine protease atg4b 0.0065 0.0156 0.0201
Echinococcus granulosus pyridine nucleotide disulfide oxidoreductase 0.0083 0.0212 0.0274
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0062 0.0146 0.0458
Onchocerca volvulus 0.0027 0.0033 0.0071
Trichomonas vaginalis ubiquitin-protein ligase BRE1, putative 0.0027 0.0033 0.0071
Trypanosoma cruzi Plus-3 domain/Zinc finger, C3HC4 type (RING finger), putative 0.0027 0.0033 0.0117
Brugia malayi hypothetical protein 0.0027 0.0033 0.0071
Onchocerca volvulus 0.0525 0.1619 0.3485
Toxoplasma gondii hypothetical protein 0.0027 0.0033 0.0071
Mycobacterium ulcerans acyl-CoA synthetase 0.0089 0.023 0.0209
Loa Loa (eye worm) hypothetical protein 0.003 0.0044 0.0095
Echinococcus granulosus expressed conserved protein 0.0169 0.0487 0.0629
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0062 0.0146 0.0458
Trichomonas vaginalis Clan CA, family C54, ATG4-like cysteine peptidase 0.0065 0.0156 0.0335
Mycobacterium ulcerans lipase/esterase 0.0087 0.0224 0.0203
Echinococcus multilocularis nuclear receptor 2DBD gamma 0.0051 0.0111 0.0144
Trichomonas vaginalis conserved hypothetical protein 0.0082 0.0208 0.0448
Echinococcus multilocularis peregrin 0.0034 0.0055 0.0071
Schistosoma mansoni tar DNA-binding protein 0.0063 0.0147 0.0161
Trypanosoma cruzi hypothetical protein, conserved 0.02 0.0583 0.207
Loa Loa (eye worm) haloacid dehalogenase-like hydrolase 0.0082 0.0208 0.0448
Plasmodium falciparum trophozoite exported protein 1 0.0027 0.0033 0.0071
Trypanosoma brucei NADPH:adrenodoxin oxidoreductase, mitochondrial, putative 0.0083 0.0212 0.0692
Trypanosoma cruzi UEV domain/Zinc finger, C3HC4 type (RING finger), putative 0.0027 0.0033 0.0117
Leishmania major hypothetical protein, conserved 0.0027 0.0033 0.0117
Trichomonas vaginalis ran, putative 0.0022 0.0018 0.0039
Trichomonas vaginalis glucosylceramidase, putative 0.0255 0.0761 0.1637
Trypanosoma brucei mitogen activated protein kinase 4, putative 0.0058 0.0133 0.0412
Brugia malayi exodeoxyribonuclease III family protein 0.0038 0.0069 0.0148
Chlamydia trachomatis dihydrolipoyl dehydrogenase 0.0312 0.0942 0.1938
Mycobacterium tuberculosis Probable nitrite reductase [NAD(P)H] large subunit [FAD flavoprotein] NirB 0.2056 0.6491 0.6483
Mycobacterium ulcerans dehydrogenase 0.0083 0.0212 0.0191
Plasmodium vivax acyl-CoA synthetase, putative 0.0032 0.0051 0.011
Mycobacterium ulcerans hydrolase 0.0087 0.0224 0.0203
Giardia lamblia Protein 21.1 0.0027 0.0033 0.016
Schistosoma mansoni rab6-interacting 0.0017 0.0001 0.0002
Schistosoma mansoni glutaminase 0.0292 0.0878 0.0962
Onchocerca volvulus 0.0027 0.0033 0.0071
Echinococcus multilocularis atpase aaa+ type core atpase aaa type core 0.1586 0.4993 0.6451
Brugia malayi Nuclear hormone receptor family member nhr-1 0.0051 0.0111 0.024
Loa Loa (eye worm) cytoplasmic intermediate filament protein 0.0016 0 0.0001
Giardia lamblia Protein 21.1 0.0027 0.0033 0.016
Mycobacterium ulcerans hydrolase 0.0082 0.0208 0.0187
Mycobacterium ulcerans lipase/esterase 0.0087 0.0224 0.0203
Mycobacterium tuberculosis Probable membrane NADH dehydrogenase NdhA 0.2056 0.6491 0.6483
Loa Loa (eye worm) GTP-binding nuclear protein RAN/TC4 0.0022 0.0018 0.0039
Toxoplasma gondii SWIB/MDM2 domain-containing protein 0.1477 0.4646 1
Trypanosoma cruzi Zinc finger, C3HC4 type (RING finger), putative 0.0027 0.0033 0.0117
Entamoeba histolytica acetyltransferase, GNAT family 0.0039 0.0072 0.0823
Echinococcus multilocularis COUP TF:Svp nuclear hormone receptor 0.0138 0.0388 0.0501
Leishmania major dihydrolipoamide dehydrogenase, putative 0.0312 0.0942 0.3344
Loa Loa (eye worm) hypothetical protein 0.0087 0.0224 0.0482
Trypanosoma brucei Zinc finger, C3HC4 type (RING finger), putative 0.0027 0.0033 0.0053
Giardia lamblia Hypothetical protein 0.0027 0.0033 0.016
Brugia malayi GTP-binding nuclear protein RAN/TC4 0.0022 0.0018 0.0039
Schistosoma mansoni dihydrolipoamide dehydrogenase 0.0312 0.0942 0.1032
Onchocerca volvulus 0.1477 0.4646 1
Treponema pallidum oxidoreductase 0.0083 0.0212 0.1636
Echinococcus granulosus pyruvate kinase 0.0036 0.0062 0.008
Plasmodium vivax dihydrolipoyl dehydrogenase, apicoplast, putative 0.0312 0.0942 0.2027
Mycobacterium tuberculosis Probable fatty-acid-CoA ligase FadD35 (fatty-acid-CoA synthetase) (fatty-acid-CoA synthase) 0.0031 0.0046 0.0025
Echinococcus multilocularis cadherin EGF LAG seven pass G type receptor 0.0065 0.0153 0.0198
Entamoeba histolytica zinc finger domain containing protein 0.0027 0.0033 0.0376
Trypanosoma cruzi hypothetical protein, conserved 0.0027 0.0033 0.0117
Trichomonas vaginalis Clan SC, family S33, methylesterase-like serine peptidase 0.0087 0.0224 0.0482
Loa Loa (eye worm) hypothetical protein 0.0024 0.0025 0.0054
Trypanosoma cruzi Zinc finger, C3HC4 type (RING finger), putative 0.0027 0.0033 0.0117
Giardia lamblia Hydrolase, putative 0.0082 0.0208 0.2056
Schistosoma mansoni hydrolase 0.0087 0.0224 0.0245
Echinococcus granulosus GPCR family 2 0.0065 0.0153 0.0198
Mycobacterium tuberculosis Probable fatty-acid-CoA ligase FadD5 (fatty-acid-CoA synthetase) (fatty-acid-CoA synthase) 0.0031 0.0046 0.0025
Mycobacterium tuberculosis Probable soluble pyridine nucleotide transhydrogenase SthA (STH) (NAD(P)(+) transhydrogenase [B-specific]) (nicotinamide nucleot 0.0312 0.0942 0.0923
Loa Loa (eye worm) steroid hormone receptor 0.0051 0.0111 0.024
Trypanosoma cruzi NADH dehydrogenase, putative 0.0083 0.0212 0.0752
Loa Loa (eye worm) nucleolar RNA-associated protein alpha 0.032 0.0966 0.208
Mycobacterium ulcerans epoxide hydrolase EphA 0.3159 1 1
Trichomonas vaginalis conserved hypothetical protein 0.0077 0.0194 0.0418
Echinococcus multilocularis glutamate synthase 0.0083 0.0212 0.0274
Trypanosoma cruzi hypothetical protein, conserved 0.0027 0.0033 0.0117
Trichomonas vaginalis glucosylceramidase, putative 0.0255 0.0761 0.1637
Loa Loa (eye worm) hypothetical protein 0.0484 0.1487 0.3201
Trypanosoma cruzi Zinc finger, C3HC4 type (RING finger), putative 0.0027 0.0033 0.0117
Brugia malayi jmjC domain containing protein 0.0099 0.0262 0.0565
Mycobacterium ulcerans haloalkane dehalogenase 0.0087 0.0224 0.0203
Mycobacterium ulcerans NADH dehydrogenase Ndh1 0.0083 0.0212 0.0191
Loa Loa (eye worm) hypothetical protein 0.0031 0.0046 0.01
Entamoeba histolytica HAD hydrolase, family IA, variant 3 0.0082 0.0208 0.2371
Onchocerca volvulus 0.0525 0.1619 0.3485
Onchocerca volvulus 0.0083 0.0212 0.0456
Loa Loa (eye worm) hypothetical protein 0.0027 0.0033 0.0071
Brugia malayi AMP-binding enzyme family protein 0.0043 0.0086 0.0185
Echinococcus multilocularis lamin dm0 0.0031 0.0046 0.0059
Leishmania major importin beta-1 subunit, putative 0.0024 0.0025 0.009
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0062 0.0146 0.0458
Echinococcus granulosus NADPH:adrenodoxin oxidoreductase 0.0083 0.0212 0.0274
Brugia malayi Pre-SET motif family protein 0.0031 0.0046 0.01
Toxoplasma gondii pyridine nucleotide-disulfide oxidoreductase domain-containing protein 0.0083 0.0212 0.0456
Trichomonas vaginalis 2-deoxyglucose-6-phosphate phosphatase, putative 0.0082 0.0208 0.0448
Echinococcus granulosus thioredoxin glutathione reductase 0.0911 0.2846 0.3677
Echinococcus granulosus Peptidase C54 0.0065 0.0156 0.0201
Loa Loa (eye worm) RING finger protein 20 0.0027 0.0033 0.0071
Schistosoma mansoni retinoid-x-receptor (RXR) 0.0051 0.0111 0.0122
Loa Loa (eye worm) hypothetical protein 0.0024 0.0025 0.0054
Echinococcus multilocularis ecdysone induced protein 78C 0.0051 0.0111 0.0144
Loa Loa (eye worm) hydrolase 0.0087 0.0224 0.0482
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0062 0.0146 0.0458
Trichomonas vaginalis ankyrin 2,3/unc44, putative 0.0027 0.0033 0.0071
Brugia malayi haloacid dehalogenase-like hydrolase family protein 0.0082 0.0208 0.0448
Loa Loa (eye worm) nuclear hormone receptor family member nhr-31 0.0051 0.0111 0.024
Treponema pallidum phosphoglycolate phosphatase 0.0082 0.0208 0.1593
Echinococcus multilocularis dihydropyrimidine dehydrogenase (NADP+) 0.0083 0.0212 0.0274
Brugia malayi nuclear receptor subfamily 1, group D, member 1, putative 0.0024 0.0025 0.0054
Loa Loa (eye worm) glutaminase 2 0.0292 0.0878 0.1889
Mycobacterium tuberculosis Probable NADH dehydrogenase Ndh 0.2056 0.6491 0.6483
Trichomonas vaginalis glucosylceramidase, putative 0.0168 0.0481 0.1036
Schistosoma mansoni nuclear hormone receptor 0.0024 0.0025 0.0027
Echinococcus multilocularis RUN 0.0017 0.0001 0.0002
Onchocerca volvulus Putative RING finger protein 207 0.0027 0.0033 0.0071
Echinococcus multilocularis pyruvate kinase 0.0036 0.0062 0.008
Trichomonas vaginalis conserved hypothetical protein 0.0027 0.0033 0.0071
Echinococcus granulosus E3 ubiquitin protein ligase Bre1 0.0027 0.0033 0.0043
Entamoeba histolytica HAD hydrolase, family IA, variant 3 0.0082 0.0208 0.2371
Loa Loa (eye worm) RNA binding protein 0.0063 0.0147 0.0317
Loa Loa (eye worm) hypothetical protein 0.0065 0.0153 0.033
Plasmodium vivax importin-beta 2, putative 0.003 0.0043 0.0093
Loa Loa (eye worm) nuclear receptor nhr-7B 0.0024 0.0025 0.0054
Schistosoma mansoni tar DNA-binding protein 0.0063 0.0147 0.0161
Mycobacterium leprae THIOREDOXIN TRXC (TRX) (MPT46) 0.0083 0.0212 0.0176
Plasmodium vivax type II NADH:ubiquinone oxidoreductase, putative 0.0083 0.0212 0.0456
Toxoplasma gondii autophagy-related cysteine peptidase atg4, putative 0.0025 0.0029 0.0062
Brugia malayi hypothetical protein 0.0027 0.0034 0.0074
Echinococcus multilocularis Transcription factor, JmjC domain containing protein 0.0099 0.0262 0.0339
Brugia malayi Pyruvate kinase, alpha/beta domain containing protein 0.0021 0.0015 0.0033
Trichomonas vaginalis neutral alpha-glucosidase ab precursor, putative 0.0031 0.0046 0.0099
Trichomonas vaginalis ankyrin repeat-containing protein, putative 0.0027 0.0033 0.0071
Schistosoma mansoni FTZ-F1 nuclear receptor-like protein 0.0051 0.0111 0.0122
Leishmania major hydrolase-like protein,esterase-like protein 0.0087 0.0224 0.0795
Mycobacterium ulcerans bromoperoxidase BpoC 0.0087 0.0224 0.0203
Mycobacterium ulcerans monoxygenase 0.0083 0.0212 0.0191
Echinococcus multilocularis E3 ubiquitin protein ligase MYLIP 0.0027 0.0033 0.0043
Trichomonas vaginalis Clan CA, family C54, ATG4-like cysteine peptidase 0.0065 0.0156 0.0335
Leishmania major AUT2/APG4/ATG4 cysteine peptidase, putative 0.0025 0.0029 0.0103
Giardia lamblia Kinase, NEK 0.0027 0.0035 0.0179
Toxoplasma gondii hypothetical protein 0.0027 0.0033 0.0071
Treponema pallidum thioredoxin reductase (trxB) 0.0083 0.0212 0.1636
Plasmodium vivax zinc finger protein, putative 0.0027 0.0033 0.0071
Trypanosoma cruzi Zn-finger in Ran binding protein and others, putative 0.0525 0.1619 0.575

Activities

Activity type Activity value Assay description Source Reference
BP (functional) = 5 mmHg tested for the percent increase in aortic blood pressure (BP) in open chest anesthetized dog at intravenous dosage of 1 mg/kg ChEMBL. 7365748
Duration (functional) = 24 min Total time in minutes elapsed from the initiation of the change until return to the pretest value of heart rate in coronary sinus of anesthetized dog at intravenous dosage of 1 mg/kg ChEMBL. 7365748
Duration (functional) = 60 min Total time in minutes elapsed from the initiation of the change until return to the pretest value of oxygen partial pressure in coronary sinus of anesthetized dog at intravenous dosage of 1 mg/kg ChEMBL. 7365748
Duration (functional) = 60 min Total time in minutes elapsed from the initiation of the change until return to the pretest value of blood pressure in coronary sinus of anesthetized dog at intravenous dosage of 1 mg/kg ChEMBL. 7365748
HR (functional) = 13 % tested for the percent increase in heart rate (HR) in open chest anesthetized dog at intravenous dosage of 1 mg/kg ChEMBL. 7365748
LD50 (functional) = 200 mg kg-1 Tested for the lethal dose in mice after administration of the compound intraperitoneally ChEMBL. 7365748
LD50 (functional) > 1000 mg kg-1 Tested for the lethal dose in mice after administration of the compound perorally ChEMBL. 7365748
PO2 (functional) = 48 % tested for percent increase in coronary sinus partial pressure of oxygen (PO2) in open chest anesthetized dog at intravenous dosage of 1 mg/kg ChEMBL. 7365748

Phenotypes

Whole-cell/tissue/organism interactions

We have no records of whole-cell/tissue assays done with this compound What does this mean?

Many chemical entities in TDR Targets come from high-throughput screenings with whole cells or tissue samples, and not all assayed compounds have been tested against a single a single target protein, probably because they get ruled out during screening process. Even if these compounds may have not been of interest in the original screening, they may come as interesting leads for other screening assays. Furthermore, we may be able to propose drug-target associations using chemical similarities and network patterns.

Annotated phenotypes:

We have no manually annotated phenotypes for this drug. What does this mean? / Care to help?
In TDR Targets, information about phenotypes that are caused by drugs, or by genetic manipulation of cells (e.g. gene knockouts or knockdowns) is manually curated from the literature. These descriptions help to describe the potential of the target for drug development. If no information is available for this gene or if the information is incomplete, this may mean that i) the papers containing this information either appeared after the curation effort for this organism was carried out or they were inadvertently missed by curators; or that ii) the curation effort for this organism has not yet started.
 
In any case, if you have information about papers containing relevant validation data for this target, please log in using your TDR Targets username and password and send them to us using the corresponding form in this page (only visible to registered users) or contact us.

External resources for this compound

Bibliographic References

1 literature reference was collected for this gene.

If you have references for this compound, please enter them in a user comment (below) or Contact us.