Detailed information for compound 1793149

Basic information

Technical information
  • Name: Unnamed compound
  • MW: 273.757 | Formula: C16H16ClNO
  • H donors: 1 H acceptors: 0 LogP: 2.9 Rotable bonds: 4
    Rule of 5 violations (Lipinski): 1
  • SMILES: Clc1ccc(cc1)COC1(CNC1)c1ccccc1
  • InChi: 1S/C16H16ClNO/c17-15-8-6-13(7-9-15)10-19-16(11-18-12-16)14-4-2-1-3-5-14/h1-9,18H,10-12H2
  • InChiKey: VZYJREYBWULEQT-UHFFFAOYSA-N  


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Synonyms

No synonyms found for this compound

Targets

Known targets for this compound

No curated genes were found associated with this compound

Predicted pathogen targets for this compound

By orthology
No druggable targets predicted by orthology data
By sequence similarity to non orthologous known druggable targets
No druggable targets predicted by sequence similarity
Obtained from network model

Ranking Plot

Putative Targets List

Species Potential target Raw Global Species
Entamoeba histolytica cysteine protease, putative 0.0016 0.0019 0.1556
Schistosoma mansoni high voltage-activated calcium channel Cav1 0.0017 0.0019 0.0019
Trypanosoma cruzi apurinic/apyrimidinic endonuclease, putative 0.0038 0.0063 0.5625
Plasmodium falciparum glycogen synthase kinase 3 0.005 0.0086 0.2228
Brugia malayi cathepsin L-like precursor 0.0011 0.0008 0.0021
Echinococcus multilocularis nuclear receptor 2DBD gamma 0.0011 0.0007 0.002
Plasmodium vivax hypothetical protein, conserved 0.0008 0.0001 0.003
Echinococcus multilocularis transient receptor potential cation channel 0.0833 0.1676 0.462
Loa Loa (eye worm) hypothetical protein 0.0017 0.0019 0.0053
Echinococcus multilocularis uncharacterized sodium dependent transporter 0.0031 0.0048 0.0133
Loa Loa (eye worm) nuclear hormone receptor family member nhr-49 0.0011 0.0007 0.002
Schistosoma mansoni voltage-gated potassium channel 0.0017 0.0019 0.0019
Schistosoma mansoni hypothetical protein 0.0339 0.0673 0.0673
Schistosoma mansoni transient receptor potential cation channel subfamily m member 0.0017 0.0019 0.0019
Schistosoma mansoni voltage-gated potassium channel 0.0017 0.0019 0.0019
Trichomonas vaginalis CMGC family protein kinase 0.005 0.0086 0.0874
Leishmania major cathepsin L-like protease 0.0016 0.0019 0.079
Loa Loa (eye worm) MH2 domain-containing protein 0.0116 0.0222 0.0612
Brugia malayi Voltage-gated potassium channel, Shaw-family (KCNC, Kv3-like) alpha-subunit 0.0017 0.0019 0.0053
Brugia malayi nuclear hormone receptor 0.0011 0.0007 0.002
Plasmodium falciparum carbon catabolite repressor protein 4, putative 0.0008 0.0001 0.003
Loa Loa (eye worm) CCR4-NOT transcription complex subunit 6 family protein 0.0008 0.0001 0.0003
Loa Loa (eye worm) runx1 0.0059 0.0105 0.029
Echinococcus multilocularis ryanodine receptor 44f 0.0017 0.0019 0.0053
Brugia malayi MH1 domain containing protein 0.0008 0.0002 0.0005
Entamoeba histolytica PH domain containing protein kinase, putative 0.0046 0.0078 0.6533
Loa Loa (eye worm) endonuclease/Exonuclease/phosphatase 0.0008 0.0001 0.0003
Mycobacterium ulcerans exodeoxyribonuclease III protein XthA 0.0038 0.0063 0.1206
Brugia malayi Papain family cysteine protease containing protein 0.0016 0.0019 0.0052
Echinococcus multilocularis potassium voltage gated channel protein 0.0017 0.0019 0.0053
Loa Loa (eye worm) pre-SET domain-containing protein family protein 0.0434 0.0867 0.239
Toxoplasma gondii 3'5'-cyclic nucleotide phosphodiesterase domain-containing protein 0.0017 0.0019 0.0497
Echinococcus granulosus cathepsin L cysteine protease 0.0008 0.0003 0.0007
Brugia malayi nuclear receptor NHR-88 0.0011 0.0007 0.002
Trichomonas vaginalis glucosylceramidase, putative 0.018 0.035 0.3543
Entamoeba histolytica cysteine proteinase 1, putative 0.0008 0.0003 0.0218
Echinococcus granulosus DNA apurinic or apyrimidinic site lyase 0.0038 0.0063 0.0173
Echinococcus granulosus sodium:potassium dependent atpase beta subunit 0.004 0.0067 0.0185
Loa Loa (eye worm) hypothetical protein 0.0031 0.0048 0.0133
Onchocerca volvulus Bile acid receptor homolog 0.0011 0.0007 0.0074
Loa Loa (eye worm) MH1 domain-containing protein 0.0008 0.0002 0.0005
Schistosoma mansoni serine/threonine protein kinase 0.0022 0.003 0.003
Trypanosoma cruzi cysteine proteinase, putative 0.0008 0.0003 0.0234
Brugia malayi GTP-binding regulatory protein Gs alpha-S chain, putative 0.0047 0.0081 0.0222
Brugia malayi calcium-independent alpha-latrotoxin receptor 2, putative 0.0016 0.0018 0.005
Loa Loa (eye worm) hypothetical protein 0.0022 0.003 0.0084
Loa Loa (eye worm) TAR-binding protein 0.0065 0.0117 0.0323
Plasmodium vivax exodeoxyribonuclease III, putative 0.0008 0.0001 0.003
Toxoplasma gondii AGC kinase 0.0062 0.0112 0.2887
Brugia malayi protein kinase C II. 0.0022 0.003 0.0084
Plasmodium falciparum cysteine proteinase falcipain 3 0.0016 0.0019 0.0482
Loa Loa (eye worm) steroid hormone receptor 0.0011 0.0007 0.002
Schistosoma mansoni subfamily A1A unassigned peptidase (A01 family) 0.0198 0.0388 0.0388
Echinococcus multilocularis voltage gated hydrogen channel 1 0.0017 0.0019 0.0053
Schistosoma mansoni voltage-gated potassium channel 0.0017 0.0019 0.0019
Brugia malayi indoleamine 2,3-dioxygenase 0.1795 0.3628 1
Trypanosoma cruzi apurinic/apyrimidinic endonuclease, putative 0.0008 0.0001 0.0104
Loa Loa (eye worm) hypothetical protein 0.0011 0.0008 0.0021
Echinococcus granulosus protein kinase c iota type 0.0022 0.003 0.0084
Schistosoma mansoni transient receptor potential cation channel subfamily m member 0.0017 0.0019 0.0019
Schistosoma mansoni voltage-gated potassium channel 0.0017 0.0019 0.0019
Trypanosoma brucei Endonuclease/Exonuclease/phosphatase family, putative 0.0008 0.0001 0.0097
Brugia malayi hypothetical protein 0.0198 0.0388 0.1069
Loa Loa (eye worm) hypothetical protein 0.0024 0.0035 0.0096
Trypanosoma cruzi Inositol phosphosphingolipids phospholipase C 0.0008 0.0001 0.0104
Brugia malayi p70 ribosomal S6 kinase beta 0.0062 0.0112 0.0309
Loa Loa (eye worm) hypothetical protein 0.0031 0.0048 0.0133
Echinococcus multilocularis voltage dependent calcium channel 0.0017 0.0019 0.0053
Brugia malayi Nuclear hormone receptor family member nhr-25 0.0011 0.0007 0.002
Trypanosoma brucei protein kinase, putative 0.005 0.0086 0.7195
Mycobacterium ulcerans glutaminase 0.0264 0.0521 1
Echinococcus multilocularis sodium dependent neurotransmitter transporter 0.0031 0.0048 0.0133
Trypanosoma cruzi Protein kinase B 0.0046 0.0078 0.7017
Schistosoma mansoni neutral sphingomyelinase 0.0008 0.0001 0.0001
Schistosoma mansoni hypothetical protein 0.0016 0.0018 0.0018
Echinococcus granulosus potassium voltage gated channel protein 0.0017 0.0019 0.0053
Mycobacterium tuberculosis Probable aldehyde dehydrogenase 0.0124 0.0236 1
Toxoplasma gondii Sodium:neurotransmitter symporter family protein 0.0031 0.0048 0.1249
Echinococcus granulosus smad 0.0008 0.0002 0.0005
Trichomonas vaginalis AGC family protein kinase 0.0066 0.012 0.1215
Loa Loa (eye worm) AGC/RSK/RSK protein kinase 0.0022 0.003 0.0084
Echinococcus multilocularis serotonin transporter 0.0182 0.0356 0.0981
Trichomonas vaginalis glucosylceramidase, putative 0.0274 0.0541 0.5477
Trichomonas vaginalis set domain proteins, putative 0.0494 0.0988 1
Entamoeba histolytica cysteine protease, putative 0.0008 0.0003 0.0218
Echinococcus granulosus ankyrin repeat protein 0.0816 0.1642 0.4527
Echinococcus multilocularis cathepsin d (lysosomal aspartyl protease) 0.0198 0.0388 0.1069
Loa Loa (eye worm) papain family cysteine protease containing protein 0.0016 0.0019 0.0052
Schistosoma mansoni cript-related 0.0008 0.0001 0.0001
Plasmodium vivax plasmepsin V, putative 0.0198 0.0388 1
Entamoeba histolytica inositol polyphosphate-5-phosphatase, putative 0.0008 0.0001 0.0097
Loa Loa (eye worm) hypothetical protein 0.0017 0.0019 0.0053
Trypanosoma cruzi cysteine peptidase, putative 0.0062 0.0112 1
Echinococcus granulosus two pore calcium channel protein 1 0.0017 0.0019 0.0053
Entamoeba histolytica cysteine protease, putative 0.0008 0.0003 0.0218
Schistosoma mansoni subfamily A1A unassigned peptidase (A01 family) 0.0198 0.0388 0.0388
Plasmodium falciparum plasmepsin VIII, putative 0.0198 0.0388 1
Loa Loa (eye worm) hypothetical protein 0.0011 0.0007 0.002
Brugia malayi glutaminase DH11.1 0.0264 0.0521 0.1437
Onchocerca volvulus Protein ultraspiracle homolog 0.0011 0.0007 0.0074
Giardia lamblia Kinase, AGC PKA 0.0042 0.007 0.8109
Loa Loa (eye worm) fibroinase 0.0016 0.0019 0.0052
Giardia lamblia Kinase, CMGC GSK 0.005 0.0086 1
Brugia malayi aspartic protease BmAsp-1, identical 0.0198 0.0388 0.1069
Trypanosoma cruzi Endonuclease/Exonuclease/phosphatase family, putative 0.0008 0.0001 0.0104
Loa Loa (eye worm) nuclear hormone receptor family member nhr-40 0.0011 0.0007 0.002
Echinococcus granulosus uncharacterized sodium dependent transporter 0.0031 0.0048 0.0133
Echinococcus granulosus tar DNA binding protein 0.0065 0.0117 0.0323
Brugia malayi Voltage-gated potassium channel, EAG (KCNH1)-related. C. elegans egl-2 ortholog 0.0017 0.0019 0.0053
Trypanosoma cruzi cysteine protease, putative 0.0008 0.0003 0.0234
Mycobacterium tuberculosis Probable chain -fatty-acid-CoA ligase FadD13 (fatty-acyl-CoA synthetase) 0.0024 0.0035 0.1471
Entamoeba histolytica PH domain containing protein kinase, putative 0.0046 0.0078 0.6533
Loa Loa (eye worm) hypothetical protein 0.0008 0.0001 0.0003
Echinococcus multilocularis histone lysine N methyltransferase SETMAR 0.0063 0.0113 0.0312
Echinococcus multilocularis potassium voltage gated channel protein 0.0017 0.0019 0.0053
Trypanosoma cruzi cysteine peptidase, putative 0.0062 0.0112 1
Loa Loa (eye worm) endonuclease/Exonuclease/phosphatase 0.0008 0.0001 0.0003
Trichomonas vaginalis glucosylceramidase, putative 0.018 0.035 0.3543
Echinococcus multilocularis aldehyde dehydrogenase, mitochondrial 0.0124 0.0236 0.0652
Echinococcus granulosus neutral sphingomyelinase 0.0008 0.0001 0.0003
Schistosoma mansoni smad 0.0008 0.0002 0.0002
Schistosoma mansoni ocrl type II inositol 5-phosphatase 0.0008 0.0001 0.0001
Echinococcus granulosus endonuclease exonuclease phosphatase 0.0008 0.0001 0.0003
Entamoeba histolytica cysteine proteinase, putative 0.0008 0.0003 0.0218
Onchocerca volvulus 0.0182 0.0356 0.36
Schistosoma mansoni inositol 145-trisphosphate receptor 0.0017 0.0019 0.0019
Trichomonas vaginalis Clan CA, family C1, cathepsin L or K-like cysteine peptidase 0.0016 0.0019 0.0189
Brugia malayi Sodium:neurotransmitter symporter family protein 0.0031 0.0048 0.0133
Loa Loa (eye worm) hypothetical protein 0.0031 0.0048 0.0133
Schistosoma mansoni transient receptor potential cation channel subfamily m member 0.0017 0.0019 0.0019
Mycobacterium ulcerans long-chain-fatty-acid--CoA ligase 0.0024 0.0035 0.0667
Trichomonas vaginalis AGC family protein kinase 0.0026 0.0038 0.0389
Echinococcus granulosus Smad4 0.0008 0.0002 0.0005
Brugia malayi Sodium:neurotransmitter symporter family protein 0.0182 0.0356 0.0981
Loa Loa (eye worm) hypothetical protein 0.047 0.0939 0.2588
Loa Loa (eye worm) nuclear hormone receptor family member nhr-14 0.0011 0.0007 0.002
Echinococcus multilocularis shaker cognate 0.0017 0.0019 0.0053
Trichomonas vaginalis ap endonuclease, putative 0.0038 0.0063 0.0636
Brugia malayi Cathepsin L-like precursor 0.0016 0.0019 0.0052
Loa Loa (eye worm) hypothetical protein 0.0017 0.0019 0.0053
Echinococcus multilocularis microtubule associated protein 2 0.0732 0.1471 0.4055
Loa Loa (eye worm) hypothetical protein 0.0017 0.0019 0.0053
Schistosoma mansoni nuclear hormone receptor 0.0011 0.0007 0.0007
Toxoplasma gondii aspartyl protease 0.0198 0.0388 1
Echinococcus granulosus nervana 2 0.004 0.0067 0.0185
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0011 0.0008 0.0078
Brugia malayi Cathepsin L-like cysteine proteinase 0.0011 0.0008 0.0021
Onchocerca volvulus Cathepsin L homolog 0.0016 0.0019 0.0189
Onchocerca volvulus 0.0016 0.0019 0.0189
Leishmania major hypothetical protein, conserved 0.0008 0.0001 0.0049
Loa Loa (eye worm) hypothetical protein 0.0018 0.0022 0.0062
Entamoeba histolytica cysteine protease, putative 0.0008 0.0003 0.0218
Onchocerca volvulus 0.0031 0.0048 0.049
Echinococcus multilocularis potassium voltage gated channel protein 0.0017 0.0019 0.0053
Echinococcus multilocularis cathepsin l cysteine peptidase 0.0016 0.0019 0.0052
Loa Loa (eye worm) hypothetical protein 0.0018 0.0022 0.0062
Echinococcus granulosus microtubule associated protein 2 0.0732 0.1471 0.4055
Echinococcus multilocularis guanine nucleotide binding protein G(s) subunit 0.0047 0.0081 0.0222
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0062 0.0112 0.931
Leishmania major 4-coumarate:coa ligase-like protein 0.0024 0.0035 0.1471
Entamoeba histolytica protein kinase domain containing protein 0.005 0.0086 0.7195
Echinococcus multilocularis nervana 2 0.004 0.0067 0.0185
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0008 0.0003 0.0218
Schistosoma mansoni ap endonuclease 0.0038 0.0063 0.0063
Plasmodium vivax acyl-CoA synthetase, putative 0.0018 0.0022 0.0576
Echinococcus multilocularis hyperpolarization activated cyclic 0.0017 0.0019 0.0053
Schistosoma mansoni vesicular amine transporter 0.0017 0.0019 0.0019
Plasmodium falciparum plasmepsin VI 0.0198 0.0388 1
Schistosoma mansoni hypothetical protein 0.1795 0.3628 0.3628
Plasmodium falciparum plasmepsin X 0.0198 0.0388 1
Plasmodium vivax vivapain-2 0.0016 0.0019 0.0482
Loa Loa (eye worm) hypothetical protein 0.0024 0.0035 0.0096
Trypanosoma brucei DNA-(apurinic or apyrimidinic site) lyase, putative 0.0008 0.0001 0.0097
Schistosoma mansoni transient receptor potential channel 0.0017 0.0019 0.0019
Echinococcus granulosus protein kinase C gamma type 0.0022 0.003 0.0084
Schistosoma mansoni synaptojanin 0.0008 0.0001 0.0001
Schistosoma mansoni cathepsin F (C01 family) 0.0016 0.0019 0.0019
Echinococcus granulosus protein kinase c epsilon type 0.0022 0.003 0.0084
Echinococcus granulosus cyclic nucleotide gated cation channel 0.0017 0.0019 0.0053
Trypanosoma cruzi Endonuclease/Exonuclease/phosphatase family, putative 0.0008 0.0001 0.0104
Loa Loa (eye worm) hypothetical protein 0.0017 0.0019 0.0053
Trichomonas vaginalis carbon catabolite repressor protein, putative 0.0008 0.0001 0.0012
Loa Loa (eye worm) hypothetical protein 0.0011 0.0007 0.002
Echinococcus granulosus potassium voltage gated channel protein 0.0017 0.0019 0.0053
Schistosoma mansoni steroid hormone receptor ad4bp 0.0011 0.0007 0.0007
Echinococcus granulosus NDR protein kinase 0.0022 0.003 0.0084
Trichomonas vaginalis Clan AA, family A1, cathepsin D-like aspartic peptidase 0.0198 0.0388 0.3923
Plasmodium vivax aspartyl protease, putative 0.0198 0.0388 1
Trichomonas vaginalis glucosylceramidase, putative 0.018 0.035 0.3543
Plasmodium vivax aspartyl proteinase, putative 0.0198 0.0388 1
Brugia malayi Nuclear hormone receptor-like 1 0.0011 0.0007 0.002
Mycobacterium ulcerans aldehyde dehydrogenase 0.0124 0.0236 0.4534
Plasmodium falciparum exodeoxyribonuclease III, putative 0.0008 0.0001 0.003
Mycobacterium tuberculosis Probable fatty-acid-CoA ligase FadD5 (fatty-acid-CoA synthetase) (fatty-acid-CoA synthase) 0.0017 0.002 0.0859
Schistosoma mansoni voltage-gated potassium channel 0.0017 0.0019 0.0019
Entamoeba histolytica protein kinase domain containing protein 0.005 0.0086 0.7195
Mycobacterium tuberculosis Probable fatty-acid-CoA ligase FadD3 (fatty-acid-CoA synthetase) (fatty-acid-CoA synthase) 0.0017 0.002 0.0859
Toxoplasma gondii hypothetical protein 0.0031 0.0048 0.1249
Trypanosoma cruzi RNA-editing complex protein MP100, putative 0.0008 0.0001 0.0104
Trichomonas vaginalis glutaminase, putative 0.0264 0.0521 0.5275
Schistosoma mansoni high voltage-activated calcium channel Cav2A 0.0017 0.0019 0.0019
Trichomonas vaginalis glucosylceramidase, putative 0.0274 0.0541 0.5477
Loa Loa (eye worm) hypothetical protein 0.0018 0.0022 0.0062
Echinococcus granulosus ribosomal protein S6 kinase alpha 3 0.0022 0.003 0.0084
Echinococcus granulosus traf and tnf receptor associated protein 0.0008 0.0001 0.0003
Echinococcus granulosus Protein kinase C brain isozyme 0.0022 0.003 0.0084
Loa Loa (eye worm) hypothetical protein 0.0011 0.0008 0.0021
Echinococcus granulosus transient receptor potential cation channel 0.0017 0.0019 0.0053
Schistosoma mansoni nocturnin 0.0008 0.0001 0.0001
Onchocerca volvulus 0.003 0.0047 0.0479
Schistosoma mansoni nuclear hormone receptor nor-1/nor-2 0.0011 0.0007 0.0007
Brugia malayi AMP-binding enzyme family protein 0.0024 0.0035 0.0096
Onchocerca volvulus 0.0016 0.0019 0.0189
Loa Loa (eye worm) AGC/PKC/ETA protein kinase 0.0022 0.003 0.0084
Brugia malayi Cathepsin L-like precursor 0.0016 0.0019 0.0052
Brugia malayi latrophilin 2 splice variant baaae 0.0035 0.0056 0.0155
Leishmania major apurinic/apyrimidinic endonuclease-redox protein 0.0038 0.0063 0.266
Toxoplasma gondii hypothetical protein 0.0017 0.0019 0.0497
Echinococcus granulosus GPCR family 2 0.0016 0.0018 0.005
Entamoeba histolytica cysteine proteinase, putative 0.0016 0.0019 0.1556
Loa Loa (eye worm) hypothetical protein 0.0017 0.0019 0.0053
Schistosoma mansoni voltage-gated potassium channel 0.0017 0.0019 0.0019
Schistosoma mansoni voltage-gated potassium channel KCNQ 0.0017 0.0019 0.0019
Schistosoma mansoni smad1 5 8 and 0.0008 0.0002 0.0002
Echinococcus multilocularis voltage dependent calcium channel 0.0017 0.0019 0.0053
Toxoplasma gondii endonuclease/exonuclease/phosphatase family protein 0.0008 0.0001 0.003
Loa Loa (eye worm) cysteine protease 0.0016 0.0019 0.0052
Loa Loa (eye worm) CMGC/GSK protein kinase 0.005 0.0086 0.0238
Echinococcus granulosus potassium:sodium hyperpolarization activated 0.0017 0.0019 0.0053
Schistosoma mansoni Smad4 0.0008 0.0002 0.0002
Toxoplasma gondii endonuclease/exonuclease/phosphatase family protein 0.0008 0.0001 0.003
Loa Loa (eye worm) hypothetical protein 0.0011 0.0008 0.0021
Entamoeba histolytica cysteine protease, putative 0.0008 0.0003 0.0218
Echinococcus multilocularis cpg binding protein 0.0032 0.0051 0.014
Trichomonas vaginalis type IV inositol 5-phosphatase, putative 0.0008 0.0001 0.0012
Leishmania major hypothetical protein, conserved 0.0017 0.0019 0.0815
Schistosoma mansoni glycogen synthase kinase 3-related (gsk3) (cmgc group III) 0.005 0.0086 0.0086
Loa Loa (eye worm) hypothetical protein 0.0017 0.0019 0.0053
Mycobacterium ulcerans acyl-CoA synthetase 0.0024 0.0035 0.0667
Schistosoma mansoni voltage-gated potassium channel 0.0017 0.0019 0.0019
Leishmania major 4-coumarate:coa ligase-like protein 0.0024 0.0035 0.1471
Plasmodium falciparum carbon catabolite repressor protein 4, putative 0.0008 0.0001 0.003
Loa Loa (eye worm) nuclear hormone receptor family member nhr-41 0.0011 0.0007 0.002
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0008 0.0003 0.0027
Echinococcus multilocularis deoxyribonuclease 1 2 0.0008 0.0001 0.0003
Echinococcus granulosus potassium voltage gated channel protein 0.0017 0.0019 0.0053
Echinococcus granulosus uncharacterized sodium dependent transporter 0.0031 0.0048 0.0133
Loa Loa (eye worm) hypothetical protein 0.0017 0.0019 0.0053
Echinococcus granulosus short transient receptor potential channel 6 0.0017 0.0019 0.0053
Loa Loa (eye worm) serotonin transporter b 0.0182 0.0356 0.0981
Loa Loa (eye worm) hypothetical protein 0.0031 0.0048 0.0133
Echinococcus multilocularis transient receptor potential cation channel 0.0017 0.0019 0.0053
Brugia malayi Pepsin A precursor 0.0198 0.0388 0.1069
Leishmania major 4-coumarate:coa ligase-like protein 0.0024 0.0035 0.1471
Loa Loa (eye worm) AGC/RSK/MSK protein kinase 0.0022 0.003 0.0084
Entamoeba histolytica protein kinase, putative 0.0062 0.0112 0.932
Echinococcus multilocularis dnaJ subfamily B 0.0434 0.0866 0.2387
Echinococcus multilocularis cysteine protease 0.0016 0.0019 0.0052
Toxoplasma gondii transporter, cation channel family protein 0.0017 0.0019 0.0497
Echinococcus granulosus cysteine protease 0.0008 0.0003 0.0007
Trichomonas vaginalis glucosylceramidase, putative 0.018 0.035 0.3543
Brugia malayi Pre-SET motif family protein 0.0434 0.0867 0.239
Schistosoma mansoni sodium/chloride dependent transporter 0.0033 0.0052 0.0052
Brugia malayi Voltage-gated potassium channel, Shaw-family (KCNC, Kv3-like) alpha-subunit. C. elegans egl-36 ortholog 0.0017 0.0019 0.0053
Schistosoma mansoni subfamily A1A unassigned peptidase (A01 family) 0.0198 0.0388 0.0388
Echinococcus multilocularis cadherin EGF LAG seven pass G type receptor 0.0016 0.0018 0.005
Echinococcus granulosus calcium activated potassium channel 0.0018 0.0022 0.0062
Trypanosoma brucei inositol-1,4,5-trisphosphate (IP3) 5-phosphatase, putative 0.0008 0.0001 0.0097
Entamoeba histolytica cysteine protease, putative 0.0008 0.0003 0.0218
Echinococcus granulosus cathepsin L cysteine proteinase 0.0016 0.0019 0.0052
Echinococcus multilocularis potassium voltage gated channel subfamily H 0.0017 0.0019 0.0053
Onchocerca volvulus Cathepsin F homolog 0.0016 0.0019 0.0189
Loa Loa (eye worm) voltage-gated calcium channel 0.0017 0.0019 0.0053
Loa Loa (eye worm) O-glycosyl hydrolase family 30 protein 0.0274 0.0541 0.1492
Schistosoma mansoni voltage-gated ion channel 0.0017 0.0019 0.0019
Echinococcus granulosus voltage dependent calcium channel 0.0017 0.0019 0.0053
Echinococcus multilocularis hepatocyte nuclear factor 4 alpha 0.0011 0.0007 0.002
Echinococcus granulosus TRP transient receptor potential channel 0.0017 0.0019 0.0053
Toxoplasma gondii Sodium:neurotransmitter symporter family protein 0.0031 0.0048 0.1249
Trichomonas vaginalis glucosylceramidase, putative 0.018 0.035 0.3543
Entamoeba histolytica acyl-CoA synthetase, putative 0.0024 0.0035 0.2895
Loa Loa (eye worm) hypothetical protein 0.0198 0.0388 0.1069
Brugia malayi MH2 domain containing protein 0.0116 0.0222 0.0612
Trichomonas vaginalis Clan CA, family C1, papain-like cysteine peptidase 0.0016 0.0019 0.0189
Trypanosoma cruzi cysteine peptidase (N-terminal), putative 0.0008 0.0003 0.0234
Echinococcus multilocularis potassium voltage gated channel subfamily C 0.0017 0.0019 0.0053
Loa Loa (eye worm) endonuclease/Exonuclease/phosphatase 0.0008 0.0001 0.0003
Loa Loa (eye worm) indoleamine 2,3-dioxygenase 0.1795 0.3628 1
Echinococcus multilocularis CCR4 NOT transcription complex subunit 6 0.0008 0.0001 0.0003
Onchocerca volvulus 0.005 0.0086 0.0874
Brugia malayi cation channel family protein 0.0017 0.0019 0.0053
Echinococcus multilocularis indoleamine 2,3 dioxygenase 2 0.1795 0.3628 1
Echinococcus granulosus potassium voltage gated channel subfamily D 0.0017 0.0019 0.0053
Echinococcus granulosus mixed lineage leukemia protein mll 0.001 0.0006 0.0015
Onchocerca volvulus 0.0011 0.0008 0.0078
Schistosoma mansoni transient receptor potential channel 0.0017 0.0019 0.0019
Trichomonas vaginalis Clan CA, family C1, papain-like cysteine peptidase 0.0016 0.0019 0.0189
Loa Loa (eye worm) RNA binding protein 0.0065 0.0117 0.0323
Schistosoma mansoni Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) 0.0047 0.0081 0.0081
Trypanosoma brucei Endonuclease/Exonuclease/phosphatase family, putative 0.0008 0.0001 0.0097
Brugia malayi Calcitonin receptor-like protein seb-1 0.0051 0.0089 0.0245
Onchocerca volvulus 0.0017 0.0019 0.0195
Toxoplasma gondii hypothetical protein 0.0031 0.0048 0.1249
Plasmodium vivax endonuclease/exonuclease/phosphatase domain containing protein 0.0008 0.0001 0.003
Plasmodium vivax glycogen synthase kinase 3, putative 0.005 0.0086 0.2228
Trichomonas vaginalis AGC family protein kinase 0.0022 0.003 0.0306
Schistosoma mansoni histone-lysine n-methyltransferase setb1 0.0063 0.0113 0.0113
Plasmodium falciparum plasmepsin IV 0.0198 0.0388 1
Loa Loa (eye worm) hypothetical protein 0.0018 0.0022 0.0062
Trichomonas vaginalis voltage and ligand gated potassium channel, putative 0.0017 0.0019 0.0195
Brugia malayi Protein kinase domain containing protein 0.0022 0.003 0.0084
Loa Loa (eye worm) hypothetical protein 0.0011 0.0007 0.002
Brugia malayi aspartic protease BmAsp-2, identical 0.0198 0.0388 0.1069
Brugia malayi Nuclear hormone receptor family member nhr-40 0.0011 0.0007 0.002
Schistosoma mansoni photoreceptor-specific nuclear receptor related 0.0011 0.0007 0.0007
Loa Loa (eye worm) hypothetical protein 0.0008 0.0001 0.0003
Echinococcus granulosus two pore calcium channel protein 2 0.0017 0.0019 0.0053
Schistosoma mansoni hypothetical protein 0.0339 0.0673 0.0673
Plasmodium falciparum AP endonuclease (DNA-[apurinic or apyrimidinic site] lyase), putative 0.0038 0.0063 0.1622
Echinococcus granulosus shaker cognate 0.0017 0.0019 0.0053
Echinococcus granulosus voltage gated potassium channel 0.0017 0.0019 0.0053
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0016 0.0019 0.0189
Echinococcus multilocularis voltage dependent calcium channel type d subunit 0.0017 0.0019 0.0053
Schistosoma mansoni Tr4/Tr2 (homologue) 0.0011 0.0007 0.0007
Echinococcus granulosus transient receptor potential cation channel 0.0017 0.0019 0.0053
Loa Loa (eye worm) hypothetical protein 0.0035 0.0056 0.0155
Schistosoma mansoni hyperpolarization activated cyclic nucleotide-gated potassium channel 0.0017 0.0019 0.0019
Schistosoma mansoni cpg binding protein 0.0032 0.0051 0.0051
Loa Loa (eye worm) endonuclease/Exonuclease/phosphatase 0.0008 0.0001 0.0003
Echinococcus granulosus geminin 0.0339 0.0673 0.1854
Schistosoma mansoni cathepsin D (A01 family) 0.0198 0.0388 0.0388
Echinococcus granulosus CCR4 NOT transcription complex subunit 6 0.0008 0.0001 0.0003
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0016 0.0019 0.0189
Echinococcus multilocularis cathepsin L 0.0008 0.0003 0.0007
Schistosoma mansoni serine/threonine protein kinase 0.0022 0.003 0.003
Echinococcus multilocularis potassium:sodium hyperpolarization activated 0.0017 0.0019 0.0053
Schistosoma mansoni voltage-gated potassium channel 0.0017 0.0019 0.0019
Echinococcus granulosus voltage gated hydrogen channel 1 0.0017 0.0019 0.0053
Schistosoma mansoni tar DNA-binding protein 0.0065 0.0117 0.0117
Echinococcus multilocularis voltage dependent L type calcium channel subunit 0.0017 0.0019 0.0053
Entamoeba histolytica endonuclease/exonuclease/phosphatase family protein 0.0008 0.0001 0.0097
Trichomonas vaginalis Clan CA, family C1, papain-like cysteine peptidase 0.0016 0.0019 0.0189
Brugia malayi Nuclear hormone receptor family member nhr-3 0.0011 0.0007 0.002
Onchocerca volvulus Cathepsin L homolog 0.0016 0.0019 0.0189
Loa Loa (eye worm) ctsf protein 0.0016 0.0019 0.0052
Onchocerca volvulus 0.0494 0.0988 1
Plasmodium falciparum endonuclease/exonuclease/phosphatase family protein, putative 0.0008 0.0001 0.003
Echinococcus multilocularis potassium voltage gated channel subfamily D 0.0017 0.0019 0.0053
Echinococcus multilocularis two pore calcium channel protein 1 0.0017 0.0019 0.0053
Echinococcus multilocularis thyroid hormone receptor alpha 0.0011 0.0007 0.002
Leishmania major glycogen synthase kinase, putative;with=GeneDB:LinJ18_V3.0270 0.005 0.0086 0.3655
Loa Loa (eye worm) hypothetical protein 0.0017 0.0019 0.0053
Echinococcus multilocularis potassium voltage gated channel subfamily H 0.0017 0.0019 0.0053
Loa Loa (eye worm) transcription factor SMAD2 0.0116 0.0222 0.0612
Echinococcus granulosus FTZ F1 nuclear receptor protein 0.0011 0.0007 0.002
Entamoeba histolytica cysteine protease, putative 0.0008 0.0003 0.0218
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0016 0.0019 0.0189
Echinococcus granulosus retinoic acid receptor rxr beta a 0.0011 0.0007 0.002
Loa Loa (eye worm) hypothetical protein 0.0031 0.0048 0.0133
Schistosoma mansoni cyclic-nucleotide-gated cation channel 0.0017 0.0019 0.0019
Trichomonas vaginalis sphingomyelinase C 2 precursor, putative 0.0008 0.0001 0.0012
Brugia malayi Sodium:neurotransmitter symporter family protein 0.0031 0.0048 0.0133
Trichomonas vaginalis glucosylceramidase, putative 0.018 0.035 0.3543
Leishmania major cathepsin L-like protease 0.0016 0.0019 0.079
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0016 0.0019 0.0189
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0062 0.0112 0.931
Schistosoma mansoni FTZ-F1 nuclear receptor-like protein 0.0011 0.0007 0.0007
Plasmodium vivax aspartyl protease, putative 0.0198 0.0388 1
Echinococcus granulosus transient receptor potential cation channel 0.0017 0.0019 0.0053
Loa Loa (eye worm) solute carrier family 6 member 4 0.0182 0.0356 0.0981
Plasmodium vivax AP endonuclease (DNA-[apurinic or apyrimidinic site] lyase), putative 0.0038 0.0063 0.1622
Schistosoma mansoni voltage-gated potassium channel 0.0017 0.0019 0.0019
Chlamydia trachomatis Ssodium-dependent amino acid transporter 0.0031 0.0048 1
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0062 0.0112 0.931
Echinococcus multilocularis traf and tnf receptor associated protein 0.0008 0.0001 0.0003
Leishmania major cathepsin L-like protease 0.0062 0.0112 0.4729
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0016 0.0019 0.0189
Brugia malayi Voltage-gated potassium channel, Shaker-family (KCNA, Kv1-like) alpha-subunit 0.0017 0.0019 0.0053
Echinococcus granulosus histone lysine methyltransferase setb 0.0063 0.0113 0.0312
Toxoplasma gondii endonuclease/exonuclease/phosphatase family protein 0.0008 0.0001 0.003
Trichomonas vaginalis skeletal muscle/kidney enriched inositol 5-phosphatase, putative 0.0008 0.0001 0.0012
Brugia malayi CCR4 0.0008 0.0001 0.0003
Trypanosoma cruzi mitochondrial protein 99, putative 0.0008 0.0001 0.0104
Schistosoma mansoni Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) 0.0047 0.0081 0.0081
Trypanosoma cruzi cysteine peptidase, putative 0.0016 0.0019 0.1671
Echinococcus multilocularis guanine nucleotide binding protein G(s) subunit 0.0047 0.0081 0.0222
Brugia malayi Nuclear hormone receptor family member nhr-1 0.0011 0.0007 0.002
Brugia malayi F/Y-rich N-terminus family protein 0.0012 0.0009 0.0025
Loa Loa (eye worm) glutaminase 2 0.0264 0.0521 0.1437
Onchocerca volvulus 0.0198 0.0388 0.3923
Schistosoma mansoni lozenge 0.0059 0.0105 0.0105
Entamoeba histolytica acyl-CoA synthetase, putative 0.0024 0.0035 0.2895
Toxoplasma gondii Sodium:neurotransmitter symporter family protein 0.0031 0.0048 0.1249
Mycobacterium ulcerans aldehyde dehydrogenase 0.0124 0.0236 0.4534
Schistosoma mansoni sodium/chloride dependent neurotransmitter transporter 0.0031 0.0048 0.0048
Mycobacterium ulcerans aldehyde dehydrogenase 0.0124 0.0236 0.4534
Trypanosoma cruzi mitochondrial protein 99, putative 0.0008 0.0001 0.0104
Echinococcus multilocularis nervana 2 0.004 0.0067 0.0185
Echinococcus multilocularis COUP TF:Svp nuclear hormone receptor 0.0011 0.0007 0.002
Echinococcus granulosus potassium voltage gated channel subfamily D 0.0017 0.0019 0.0053
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0062 0.0112 0.931
Echinococcus multilocularis cysteine protease 0.0016 0.0019 0.0052
Onchocerca volvulus 0.0198 0.0388 0.3923
Schistosoma mansoni tar DNA-binding protein 0.0065 0.0117 0.0117
Echinococcus multilocularis atpase aaa+ type core atpase aaa type core 0.0791 0.159 0.4384
Entamoeba histolytica acyl-coA synthetase, putative 0.0024 0.0035 0.2895
Wolbachia endosymbiont of Brugia malayi exonuclease III 0.0038 0.0063 0.5
Schistosoma mansoni RAR-like nuclear receptor 0.0011 0.0007 0.0007
Schistosoma mansoni subfamily A1A unassigned peptidase (A01 family) 0.0198 0.0388 0.0388
Onchocerca volvulus 0.0024 0.0035 0.0352
Echinococcus multilocularis inositol polyphosphate 5 phosphatase OCRL 1 0.0008 0.0001 0.0003
Echinococcus granulosus sodium dependent neurotransmitter transporter 0.0031 0.0048 0.0133
Schistosoma mansoni subfamily A1A unassigned peptidase (A01 family) 0.0198 0.0388 0.0388
Trypanosoma brucei Inositol phosphosphingolipids phospholipase C 0.0008 0.0001 0.0097
Schistosoma mansoni cathepsin D (A01 family) 0.0198 0.0388 0.0388
Echinococcus granulosus dnaJ subfamily B 0.0434 0.0866 0.2387
Trypanosoma cruzi pantothenate kinase subunit, putative 0.0009 0.0003 0.0284
Echinococcus multilocularis mothers against decapentaplegic 5 0.0008 0.0002 0.0005
Plasmodium vivax vivapain-1 0.0008 0.0003 0.0068
Toxoplasma gondii histone lysine methyltransferase SET/SUV39 0.0063 0.0113 0.2917
Loa Loa (eye worm) ryanodine receptor 0.0017 0.0019 0.0053
Schistosoma mansoni norepinephrine/norepinephrine transporter 0.0031 0.0048 0.0048
Echinococcus multilocularis serine threonine protein kinase 0.0022 0.003 0.0084
Leishmania major cathepsin L-like protease 0.0016 0.0019 0.079
Brugia malayi Nuclear hormone receptor family member nhr-25 0.0011 0.0007 0.002
Loa Loa (eye worm) hypothetical protein 0.0024 0.0035 0.0096
Loa Loa (eye worm) cyclic-nucleotide gated cation channel 0.0017 0.0019 0.0053
Brugia malayi Protein kinase domain containing protein 0.0022 0.003 0.0084
Loa Loa (eye worm) hypothetical protein 0.0063 0.0113 0.0312
Echinococcus multilocularis short transient receptor potential channel 6 0.0017 0.0019 0.0053
Toxoplasma gondii endonuclease/exonuclease/phosphatase family protein 0.0008 0.0001 0.003
Plasmodium falciparum DNase I-like protein, putative 0.0008 0.0001 0.003
Schistosoma mansoni cyclic-nucleotide-gated cation channel 0.0017 0.0019 0.0019
Brugia malayi Large-conductance calcium-activated potassium channel Slo-1 (KCNMA) alpha subunit. C. elegans slo-1 ortholog 0.0017 0.0019 0.0053
Echinococcus multilocularis histone lysine methyltransferase setb histone lysine methyltransferase eggless 0.0063 0.0113 0.0312
Echinococcus multilocularis voltage gated potassium channel 0.0017 0.0019 0.0053
Schistosoma mansoni subfamily A1A unassigned peptidase (A01 family) 0.0198 0.0388 0.0388
Loa Loa (eye worm) hypothetical protein 0.0198 0.0388 0.1069
Brugia malayi RNA recognition motif domain containing protein 0.0065 0.0117 0.0323
Entamoeba histolytica cysteine protease, putative 0.0008 0.0003 0.0218
Echinococcus granulosus hepatocyte nuclear factor 4 alpha 0.0011 0.0007 0.002
Trypanosoma brucei inositol/phosphatidylinositol phosphatase, putative 0.0008 0.0001 0.0097
Echinococcus multilocularis potassium voltage gated channel subfamily KQT 0.0017 0.0019 0.0053
Onchocerca volvulus 0.0016 0.0019 0.0189
Schistosoma mansoni retinoic acid receptor RXR 0.0011 0.0007 0.0007
Leishmania major inositol phosphosphingolipid phospholipase C-Like 0.0008 0.0001 0.0049
Trypanosoma cruzi endonuclease/exonuclease/phosphatase, putative 0.0008 0.0001 0.0104
Schistosoma mansoni two-pore calcium channel 0.0017 0.0019 0.0019
Trichomonas vaginalis Clan CA, family C1, papain-like cysteine peptidase 0.0016 0.0019 0.0189
Brugia malayi Nuclear hormone receptor family member nhr-19 0.0011 0.0007 0.002
Loa Loa (eye worm) hypothetical protein 0.0017 0.0019 0.0053
Schistosoma mansoni microtubule-associated protein tau 0.0732 0.1471 0.1471
Trypanosoma brucei RNA editing exonuclease 2 0.0008 0.0001 0.0097
Brugia malayi Cathepsin L-like precursor 0.0016 0.0019 0.0052
Loa Loa (eye worm) AGC/AKT protein kinase 0.0066 0.012 0.0331
Leishmania major hypothetical protein, conserved 0.0008 0.0001 0.0049
Onchocerca volvulus 0.0016 0.0019 0.0189
Echinococcus granulosus ribosomal protein s6 kinase beta 1 0.0022 0.003 0.0084
Loa Loa (eye worm) hypothetical protein 0.0011 0.0007 0.002
Schistosoma mansoni Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) 0.0047 0.0081 0.0081
Brugia malayi Voltage-gated calcium channel, P/Q-type, alpha subunit. C. elegans unc-2 ortholog 0.0017 0.0019 0.0053
Echinococcus multilocularis protein kinase c epsilon type 0.0022 0.003 0.0084
Echinococcus granulosus Potassium voltage gated channel protein Shaw 0.0017 0.0019 0.0053
Echinococcus granulosus Glutaredoxin protein 5 0.004 0.0067 0.0185
Echinococcus multilocularis TGF beta signal transducer SmadC 0.0008 0.0002 0.0005
Loa Loa (eye worm) hypothetical protein 0.0017 0.0019 0.0053
Schistosoma mansoni subfamily A1A unassigned peptidase (A01 family) 0.0198 0.0388 0.0388
Echinococcus granulosus indoleamine 23 dioxygenase 2 0.1795 0.3628 1
Schistosoma mansoni smad1 5 8 and 0.0008 0.0002 0.0002
Leishmania major cysteine peptidase A (CPA) 0.0016 0.0019 0.079
Echinococcus multilocularis voltage dependent L type calcium channel subunit 0.0017 0.0019 0.0053
Trypanosoma cruzi inositol 1,4,5-trisphosphate receptor, putative 0.0017 0.0019 0.1724
Echinococcus multilocularis diuretic hormone 44 receptor GPRdih2 0.0016 0.0018 0.005
Entamoeba histolytica exodeoxyribonuclease III, putative 0.0038 0.0063 0.5237
Onchocerca volvulus Putative neutral sphingomyelinase 0.0008 0.0001 0.0012
Brugia malayi olfactory channel protein osm-9 0.0017 0.0019 0.0053
Brugia malayi CXXC zinc finger family protein 0.003 0.0047 0.0131
Plasmodium falciparum plasmepsin V 0.0198 0.0388 1
Brugia malayi Cathepsin L-like precursor 0.0016 0.0019 0.0052
Loa Loa (eye worm) hypothetical protein 0.0017 0.0019 0.0053
Brugia malayi Nuclear hormone receptor family member nhr-14 0.0011 0.0007 0.002
Loa Loa (eye worm) glutaminase 0.0264 0.0521 0.1437
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0016 0.0019 0.0189
Echinococcus multilocularis potassium voltage gated channel subfamily D 0.0017 0.0019 0.0053
Entamoeba histolytica endonuclease/exonuclease/phosphatase family protein 0.0008 0.0001 0.0097
Trichomonas vaginalis type II inositol 5-phosphatase, putative 0.0008 0.0001 0.0012
Trichomonas vaginalis AGC family protein kinase 0.0066 0.012 0.1215
Loa Loa (eye worm) hypothetical protein 0.0031 0.0048 0.0133
Trypanosoma cruzi cysteine proteinase, putative 0.0008 0.0003 0.0234
Echinococcus multilocularis potassium large conductance calcium activated 0.0017 0.0019 0.0053
Mycobacterium ulcerans hypothetical protein 0.0024 0.0035 0.0667
Trypanosoma cruzi Voltage-dependent calcium channel subunit, putative 0.0017 0.0019 0.1724
Brugia malayi Voltage-gated calcium channel, T-type, alpha subunit. C. elegans cca-1 ortholog 0.0017 0.0019 0.0053
Echinococcus granulosus serotonin transporter 0.0182 0.0356 0.0981
Entamoeba histolytica cysteine proteinase 2 0.0008 0.0003 0.0218
Entamoeba histolytica endonuclease/exonuclease/phosphatase domain containing protein 0.0008 0.0001 0.0097
Echinococcus granulosus cpg binding protein 0.0032 0.0051 0.014
Schistosoma mansoni synaptojanin 0.0008 0.0001 0.0001
Brugia malayi ecdysteroid receptor 0.0011 0.0007 0.002
Echinococcus multilocularis Protein lozenge 0.0059 0.0105 0.029
Schistosoma mansoni 60S ribosomal protein L21 0.0017 0.0019 0.0019
Loa Loa (eye worm) Sodium:neurotransmitter symporter family protein 0.0031 0.0048 0.0133
Schistosoma mansoni calcium channel voltage-dependent p/q type alpha 1a-related 0.0017 0.0019 0.0019
Loa Loa (eye worm) hypothetical protein 0.0017 0.0019 0.0053
Schistosoma mansoni ap endonuclease 0.0038 0.0063 0.0063
Trichomonas vaginalis AGC family protein kinase 0.0066 0.012 0.1215
Loa Loa (eye worm) hypothetical protein 0.0182 0.0356 0.0981
Echinococcus multilocularis nuclear receptor 2DBD gamma 0.0011 0.0007 0.002
Echinococcus granulosus protein kinase shaggy 0.005 0.0086 0.0238
Echinococcus granulosus potassium voltage gated channel protein 0.0017 0.0019 0.0053
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0016 0.0019 0.0189
Trypanosoma brucei rac serine-threonine kinase, putative 0.0066 0.012 1
Plasmodium falciparum cysteine proteinase falcipain 2b 0.0016 0.0019 0.0482
Mycobacterium tuberculosis Probable fatty-acid-CoA ligase FadD7 (fatty-acid-CoA synthetase) (fatty-acid-CoA synthase) 0.0017 0.002 0.0859
Echinococcus multilocularis sodium:potassium dependent atpase beta subunit 0.004 0.0067 0.0185
Echinococcus granulosus serine/threonine protein kinase 0.0046 0.0078 0.0216
Leishmania major aldehyde dehydrogenase, mitochondrial precursor 0.0124 0.0236 1
Echinococcus multilocularis endonuclease exonuclease phosphatase 0.0008 0.0001 0.0003
Toxoplasma gondii histone lysine methyltransferase SET1 0.006 0.0107 0.2767
Echinococcus multilocularis Ribosomal protein S6 kinase beta 2 0.0022 0.003 0.0084
Echinococcus multilocularis potassium voltage gated channel subfamily A 0.0017 0.0019 0.0053
Schistosoma mansoni mixed-lineage leukemia protein mll 0.0067 0.0121 0.0121
Loa Loa (eye worm) Smad1 0.0008 0.0002 0.0005
Trichomonas vaginalis CMGC family protein kinase 0.005 0.0086 0.0874
Schistosoma mansoni histone-lysine n-methyltransferase suv9 0.0063 0.0113 0.0113
Echinococcus granulosus transient receptor potential cation channel 0.0017 0.0019 0.0053
Plasmodium vivax unspecified product 0.0008 0.0003 0.0068
Loa Loa (eye worm) aspartic protease BmAsp-1 0.0198 0.0388 0.1069
Echinococcus granulosus potassium voltage gated channel subfamily D 0.0017 0.0019 0.0053
Echinococcus granulosus hyperpolarization activated cyclic 0.0017 0.0019 0.0053
Echinococcus multilocularis glycogen synthase kinase 3 beta 0.005 0.0086 0.0238
Echinococcus multilocularis serine:threonine protein kinase N2 0.0022 0.003 0.0084
Entamoeba histolytica cysteine proteinase, putative 0.0008 0.0003 0.0218
Echinococcus multilocularis histone lysine N methyltransferase MLL3 0.0012 0.0009 0.0026
Schistosoma mansoni transient receptor potential cation channel subfamily m member 0.0017 0.0019 0.0019
Schistosoma mansoni hypothetical protein 0.0008 0.0001 0.0001
Schistosoma mansoni sodium/chloride dependent neurotransmitter transporter 0.0031 0.0048 0.0048
Onchocerca volvulus 0.0016 0.0019 0.0189
Echinococcus granulosus short transient receptor potential channel 6 0.0017 0.0019 0.0053
Entamoeba histolytica cysteine protease, putative 0.0008 0.0003 0.0218
Schistosoma mansoni SmCL2-like peptidase (C01 family) 0.0008 0.0003 0.0003
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0062 0.0112 0.931
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0062 0.0112 0.931
Plasmodium falciparum acyl-CoA synthetase 0.0018 0.0022 0.0576
Echinococcus multilocularis serine:threonine protein kinase N2 0.0022 0.003 0.0084
Brugia malayi Hr1 repeat family protein 0.0022 0.003 0.0084
Echinococcus multilocularis transient receptor potential cation channel 0.0017 0.0019 0.0053
Loa Loa (eye worm) hypothetical protein 0.047 0.0939 0.2588
Echinococcus multilocularis mixed lineage leukemia protein mll 0.001 0.0006 0.0015
Brugia malayi Voltage-gated potassium channel, Shaw-family (KCNC, Kv3-like) alpha-subunit 0.0017 0.0019 0.0053
Plasmodium falciparum cysteine proteinase falcipain 2a 0.0016 0.0019 0.0482
Echinococcus granulosus nuclear receptor 2DBD gamma 0.0011 0.0007 0.002
Schistosoma mansoni nuclear receptor 2DBD-gamma 0.0011 0.0007 0.0007
Loa Loa (eye worm) cyclic-nucleotide gated cation channel 0.0017 0.0019 0.0053
Loa Loa (eye worm) hypothetical protein 0.0051 0.0089 0.0245
Echinococcus multilocularis transient receptor potential cation channel 0.0017 0.0019 0.0053
Loa Loa (eye worm) hypothetical protein 0.0017 0.0019 0.0053
Schistosoma mansoni sodium/chloride dependent transporter 0.0182 0.0356 0.0356
Trypanosoma cruzi cruzipain precursor, putative 0.0062 0.0112 1
Echinococcus granulosus cadherin EGF LAG seven pass G type receptor 0.0016 0.0018 0.005
Echinococcus granulosus serine:threonine protein kinase N2 0.0022 0.003 0.0084
Brugia malayi Endonuclease/Exonuclease/phosphatase family protein 0.0008 0.0001 0.0003
Loa Loa (eye worm) AGC/NDR protein kinase 0.0022 0.003 0.0084
Schistosoma mansoni hypothetical protein 0.0016 0.0018 0.0018
Echinococcus granulosus serine threonine protein kinase nrc 0.0042 0.007 0.0194
Echinococcus multilocularis short transient receptor potential channel 6 0.0017 0.0019 0.0053
Trichomonas vaginalis AGC family protein kinase 0.0066 0.012 0.1215
Plasmodium falciparum plasmepsin III 0.0198 0.0388 1
Loa Loa (eye worm) calcium channel 0.0017 0.0019 0.0053
Leishmania major cathepsin L-like protease 0.0062 0.0112 0.4729
Onchocerca volvulus 0.047 0.0939 0.9498
Mycobacterium leprae PROBABLE FATTY-ACID-CoA LIGASE FADD2 (FATTY-ACID-CoA SYNTHETASE) (FATTY-ACID-CoA SYNTHASE) 0.0024 0.0035 1
Onchocerca volvulus Steroid hormone receptor family member cnr14 homolog 0.0011 0.0007 0.0074
Echinococcus multilocularis voltage dependent calcium channel type d subunit 0.0017 0.0019 0.0053
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0062 0.0112 0.931
Plasmodium falciparum plasmepsin VII 0.0198 0.0388 1
Brugia malayi Steroid receptor seven-up type 2 0.0011 0.0007 0.002
Echinococcus granulosus calcium:calmodulin dependent protein kinase 0.0042 0.007 0.0194
Giardia lamblia Kinase, CMGC GSK 0.005 0.0086 1
Plasmodium vivax hypothetical protein, conserved 0.0031 0.0048 0.1249
Schistosoma mansoni serine/threonine-protein kinase 0.0046 0.0078 0.0078
Schistosoma mansoni hypothetical protein 0.0016 0.0018 0.0018
Schistosoma mansoni hypothetical protein 0.0017 0.0019 0.0019
Brugia malayi Endonuclease/Exonuclease/phosphatase family protein 0.0008 0.0001 0.0003
Trypanosoma cruzi cysteine peptidase, putative 0.0062 0.0112 1
Loa Loa (eye worm) hypothetical protein 0.0017 0.0019 0.0053
Brugia malayi photoreceptor-specific nuclear receptor 0.0011 0.0007 0.002
Loa Loa (eye worm) hypothetical protein 0.0017 0.0019 0.0053
Echinococcus multilocularis potassium voltage gated channel protein 0.0017 0.0019 0.0053
Echinococcus multilocularis cyclic nucleotide gated cation channel 0.0017 0.0019 0.0053
Echinococcus multilocularis rac serine:threonine kinase 0.0046 0.0078 0.0216
Echinococcus multilocularis transient receptor potential cation channel 0.0017 0.0019 0.0053
Entamoeba histolytica cysteine protease, putative 0.0008 0.0003 0.0218
Plasmodium falciparum cysteine proteinase falcipain 1 0.0008 0.0003 0.0068
Trypanosoma cruzi Endonuclease/Exonuclease/phosphatase family, putative 0.0008 0.0001 0.0104
Echinococcus granulosus COUP TF:Svp nuclear hormone receptor 0.0011 0.0007 0.002
Entamoeba histolytica cysteine proteinase, putative 0.0011 0.0008 0.0644
Echinococcus granulosus voltage dependent L type calcium channel subunit|voltage dependent calcium channel 0.0017 0.0019 0.0053
Echinococcus multilocularis protein kinase c iota type 0.0022 0.003 0.0084
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0016 0.0019 0.0189
Toxoplasma gondii endonuclease/exonuclease/phosphatase family protein 0.0008 0.0001 0.003
Trichomonas vaginalis Clan CA, family C1, papain-like cysteine peptidase 0.0016 0.0019 0.0189
Schistosoma mansoni SmCL2-like peptidase (C01 family) 0.0008 0.0003 0.0003
Trichomonas vaginalis AGC family protein kinase 0.0066 0.012 0.1215
Schistosoma mansoni cyclic-nucleotide-gated cation channel 0.0017 0.0019 0.0019
Loa Loa (eye worm) voltage-dependent calcium channel 0.0017 0.0019 0.0053
Schistosoma mansoni mixed-lineage leukemia protein mll 0.001 0.0006 0.0006
Echinococcus granulosus cathepsin d lysosomal aspartyl protease 0.0198 0.0388 0.1069
Plasmodium vivax SET domain protein, putative 0.0063 0.0113 0.2917
Brugia malayi Cathepsin L-like precursor 0.0016 0.0019 0.0052
Echinococcus granulosus cathepsin L 0.0008 0.0003 0.0007
Toxoplasma gondii transporter, cation channel family protein 0.0017 0.0019 0.0497
Echinococcus multilocularis two pore calcium channel protein 2 0.0017 0.0019 0.0053
Echinococcus multilocularis cathepsin L cysteine protease 0.0016 0.0019 0.0052
Leishmania major cathepsin L-like protease 0.0016 0.0019 0.079
Trichomonas vaginalis carbon catabolite repressor protein, putative 0.0008 0.0001 0.0012
Brugia malayi Latrophilin receptor protein 2 0.0016 0.0018 0.005
Echinococcus granulosus sodium channel protein 0.0017 0.0019 0.0053
Onchocerca volvulus Glucosylceramidase homolog 0.018 0.035 0.3543
Loa Loa (eye worm) AGC/RSK/P70 protein kinase 0.0062 0.0112 0.0309
Loa Loa (eye worm) hypothetical protein 0.0198 0.0388 0.1069
Loa Loa (eye worm) aspartic protease BmAsp-2 0.0198 0.0388 0.1069
Loa Loa (eye worm) latrophilin receptor protein 2 0.0016 0.0018 0.005
Schistosoma mansoni serine/threonine protein kinase 0.0022 0.003 0.003
Loa Loa (eye worm) hypothetical protein 0.0011 0.0007 0.002
Echinococcus granulosus transient receptor potential gamma protein 0.0017 0.0019 0.0053
Brugia malayi Protein kinase domain containing protein 0.0066 0.012 0.0331
Mycobacterium tuberculosis Probable fatty-acid-CoA ligase FadD35 (fatty-acid-CoA synthetase) (fatty-acid-CoA synthase) 0.0017 0.002 0.0859
Schistosoma mansoni carbon catabolite repressor protein 0.0008 0.0001 0.0001
Loa Loa (eye worm) nuclear hormone receptor family member nhr-1 0.0011 0.0007 0.002
Schistosoma mansoni sodium-dependent neurotransmitter transporter 0.0031 0.0048 0.0048
Loa Loa (eye worm) norepinephrine transporter 0.0182 0.0356 0.0981
Trichomonas vaginalis Clan CA, family C1, cathepsin L or K-like cysteine peptidase 0.0016 0.0019 0.0189
Schistosoma mansoni sodium/chloride dependent neurotransmitter transporter 0.0031 0.0048 0.0048
Schistosoma mansoni voltage-gated potassium channel 0.0017 0.0019 0.0019
Echinococcus multilocularis Smad4 0.0008 0.0002 0.0005
Mycobacterium ulcerans acyl-CoA synthetase 0.0024 0.0035 0.0667
Echinococcus granulosus transient receptor potential cation channel 0.0833 0.1676 0.462
Plasmodium vivax vivapain-3 0.0008 0.0003 0.0068
Plasmodium vivax vivapain-2 0.0016 0.0019 0.0482
Brugia malayi Nuclear hormone receptor family member nhr-49 0.0011 0.0007 0.002
Mycobacterium tuberculosis Fatty-acid-AMP ligase FadD30 (fatty-acid-AMP synthetase) (fatty-acid-AMP synthase) 0.0018 0.0022 0.0944
Entamoeba histolytica cysteine protease, putative 0.0008 0.0003 0.0218
Loa Loa (eye worm) ion channel NompC 0.0017 0.0019 0.0053
Echinococcus granulosus potassium channel KvQLT family member kqt 1 0.0017 0.0019 0.0053
Echinococcus granulosus guanine nucleotide binding protein Gs subunit 0.0047 0.0081 0.0222
Plasmodium falciparum plasmepsin I 0.0198 0.0388 1
Echinococcus multilocularis sodium channel protein 0.0017 0.0019 0.0053
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0016 0.0019 0.0189
Schistosoma mansoni voltage-gated potassium channel 0.0017 0.0019 0.0019
Schistosoma mansoni voltage-gated potassium channel 0.0017 0.0019 0.0019
Schistosoma mansoni cpg binding protein 0.0032 0.0051 0.0051
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0062 0.0112 0.931
Echinococcus multilocularis TRP (transient receptor potential) channel 0.0017 0.0019 0.0053
Schistosoma mansoni sodium-dependent neurotransmitter transporter 0.0031 0.0048 0.0048
Echinococcus granulosus Nuclear hormone receptor family member nhr 41 0.0011 0.0007 0.002
Plasmodium falciparum plasmepsin IX 0.0198 0.0388 1
Loa Loa (eye worm) pigment dispersing factor receptor c 0.0051 0.0089 0.0245
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0062 0.0112 0.931
Trypanosoma cruzi Endonuclease/Exonuclease/phosphatase family, putative 0.0008 0.0001 0.0104
Loa Loa (eye worm) Papain cysteine protease/cathepsin propeptide inhibitor-containing protein 0.0016 0.0019 0.0052
Entamoeba histolytica cysteine proteinase, putative 0.0008 0.0003 0.0218
Echinococcus multilocularis neutral sphingomyelinase 0.0008 0.0001 0.0003
Schistosoma mansoni cathepsin F (C01 family) 0.0016 0.0019 0.0019
Echinococcus granulosus transient receptor potential cation channel 0.0017 0.0019 0.0053
Entamoeba histolytica endonuclease/exonuclease/phosphatase family protein 0.0008 0.0001 0.0097
Loa Loa (eye worm) AGC/DMPK/GEK protein kinase 0.0022 0.003 0.0084
Trypanosoma brucei inositol 1,4,5-trisphosphate receptor 0.0017 0.0019 0.1605
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0016 0.0019 0.0189
Loa Loa (eye worm) CMGC/GSK protein kinase 0.005 0.0086 0.0238
Trichomonas vaginalis glucosylceramidase, putative 0.0189 0.037 0.3742
Plasmodium falciparum amino acid transporter, putative 0.0031 0.0048 0.1249
Trichomonas vaginalis AGC family protein kinase 0.0022 0.003 0.0306
Brugia malayi voltage-dependent calcium channel 0.0017 0.0019 0.0053
Brugia malayi Cyclic-nucleotide gated cation channel 0.0017 0.0019 0.0053
Loa Loa (eye worm) hypothetical protein 0.0017 0.0019 0.0053
Echinococcus granulosus FTZ F1 alpha 0.0011 0.0007 0.002
Echinococcus granulosus histone lysine N methyltransferase MLL3 0.0012 0.0009 0.0026
Echinococcus multilocularis transient receptor potential gamma protein 0.0017 0.0019 0.0053
Brugia malayi TAR-binding protein 0.0065 0.0117 0.0323
Schistosoma mansoni cathepsin F (C01 family) 0.0011 0.0008 0.0008
Loa Loa (eye worm) voltage-gated potassium channel 0.0017 0.0019 0.0053
Schistosoma mansoni transient receptor potential channel 4 0.0017 0.0019 0.0019
Toxoplasma gondii eukaryotic aspartyl protease superfamily protein 0.0198 0.0388 1
Plasmodium vivax amine transporter, putative 0.0031 0.0048 0.1249
Echinococcus granulosus voltage dependent calcium channel type d subunit|voltage dependent calcium channel|voltage dependent L type calcium channel subu 0.0017 0.0019 0.0053
Brugia malayi Nuclear hormone receptor family member nhr-41 0.0011 0.0007 0.002
Echinococcus multilocularis ankyrin repeat protein 0.0816 0.1642 0.4527
Echinococcus granulosus TGF beta signal transducer SmadC 0.0008 0.0002 0.0005
Toxoplasma gondii aspartyl protease ASP3 0.0198 0.0388 1
Brugia malayi O-Glycosyl hydrolase family 30 protein 0.0274 0.0541 0.1492
Schistosoma mansoni hypothetical protein 0.0035 0.0056 0.0056
Giardia lamblia Endonuclease/Exonuclease/phosphatase 0.0038 0.0063 0.7242
Echinococcus granulosus sodium and chloride dependent glycine 0.0031 0.0048 0.0133
Loa Loa (eye worm) GTP-binding regulatory protein Gs alpha-S chain 0.0047 0.0081 0.0222
Trichomonas vaginalis glucosylceramidase, putative 0.0274 0.0541 0.5477
Trypanosoma cruzi glycogen synthase kinase 3, putative 0.005 0.0086 0.7728
Schistosoma mansoni hypothetical protein 0.1795 0.3628 0.3628
Schistosoma mansoni retinoid-x-receptor (RXR) 0.0011 0.0007 0.0007
Toxoplasma gondii exonuclease III APE 0.0038 0.0063 0.1622
Schistosoma mansoni hyperpolarization activated cyclic nucleotide-gated potassium channel 0.0017 0.0019 0.0019
Leishmania major pantothenate kinase subunit, putative 0.0009 0.0003 0.0134
Echinococcus multilocularis synaptojanin 1 0.0008 0.0001 0.0003
Loa Loa (eye worm) aspartyl protease 6 0.0198 0.0388 0.1069
Echinococcus multilocularis hyperpolarization activated cyclic 0.0017 0.0019 0.0053
Trichomonas vaginalis glucosylceramidase, putative 0.0189 0.037 0.3742
Echinococcus granulosus hypothetical protein 0.0017 0.0019 0.0053
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0008 0.0003 0.0027
Schistosoma mansoni voltage-gated potassium channel 0.0017 0.0019 0.0019
Echinococcus granulosus mothers against decapentaplegic 5 0.0008 0.0002 0.0005
Onchocerca volvulus Transient receptor potential cation channel trpm homolog 0.0017 0.0019 0.0195
Brugia malayi Cathepsin L-like precursor 0.0011 0.0008 0.0021
Trypanosoma brucei Voltage-dependent calcium channel subunit, putative 0.0017 0.0019 0.1605
Schistosoma mansoni transient receptor potential channel 0.0017 0.0019 0.0019
Leishmania major hypothetical protein, unknown function 0.0017 0.0019 0.0815
Echinococcus multilocularis sodium and chloride dependent glycine 0.0031 0.0048 0.0133
Echinococcus multilocularis FTZ F1 alpha 0.0011 0.0007 0.002
Mycobacterium leprae PROBABLE FATTY-ACID-CoA LIGASE FADD7 (FATTY-ACID-CoA SYNTHETASE) (FATTY-ACID-CoA SYNTHASE) 0.0024 0.0035 1
Echinococcus multilocularis protein kinase shaggy 0.005 0.0086 0.0238
Plasmodium vivax aspartyl protease, putative 0.0198 0.0388 1
Entamoeba histolytica protein kinase, putative 0.0022 0.003 0.2522
Schistosoma mansoni voltage-gated cation channel 0.0017 0.0019 0.0019
Onchocerca volvulus 0.0008 0.0001 0.0012
Loa Loa (eye worm) AGC/PKN protein kinase 0.0022 0.003 0.0084
Schistosoma mansoni sodium-dependent neurotransmitter transporter 0.0031 0.0048 0.0048
Schistosoma mansoni voltage-gated potassium channel 0.0017 0.0019 0.0019
Echinococcus multilocularis Glutaredoxin protein 5 0.004 0.0067 0.0185
Mycobacterium ulcerans long-chain fatty-acid CoA ligase 0.0024 0.0035 0.0667
Schistosoma mansoni tar DNA-binding protein 0.0065 0.0117 0.0117
Echinococcus multilocularis Nuclear hormone receptor family member nhr 41 0.0011 0.0007 0.002
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0062 0.0112 0.931
Brugia malayi Cathepsin L-like precursor 0.0016 0.0019 0.0052
Schistosoma mansoni calcium-activated potassium channel 0.0017 0.0019 0.0019
Echinococcus granulosus sodium:chloride dependent neurotransmitter 0.0031 0.0048 0.0133
Schistosoma mansoni voltage-gated potassium channel 0.0017 0.0019 0.0019
Plasmodium vivax endonuclease/exonuclease/phosphatase domain containing protein 0.0008 0.0001 0.003
Brugia malayi Nuclear hormone receptor family member nhr-31 0.0011 0.0007 0.002
Brugia malayi Ligand-binding domain of nuclear hormone receptor family protein 0.0011 0.0007 0.002
Mycobacterium ulcerans acyl-CoA synthetase 0.0024 0.0035 0.0667
Schistosoma mansoni glutaminase 0.0264 0.0521 0.0521
Echinococcus granulosus cyclic nucleotide gated cation channel 0.0017 0.0019 0.0053
Leishmania major hypothetical protein, conserved 0.0008 0.0001 0.0049
Entamoeba histolytica endonuclease/exonuclease/phosphatase family protein 0.0008 0.0001 0.0097
Brugia malayi hypothetical protein 0.047 0.0939 0.2588
Leishmania major cathepsin L-like protease 0.0016 0.0019 0.079
Trypanosoma cruzi rac serine-threonine kinase, putative 0.0042 0.007 0.6286
Entamoeba histolytica cysteine protease, putative 0.0008 0.0003 0.0218
Entamoeba histolytica protein kinase, putative 0.0066 0.012 1
Leishmania major RNA-editing complex protein MP100, putative 0.0008 0.0001 0.0049
Echinococcus granulosus voltage dependent calcium channel type d subunit|voltage dependent calcium channel alpha 1 0.0017 0.0019 0.0053
Entamoeba histolytica cysteine proteinase, putative 0.0008 0.0003 0.0218
Brugia malayi Voltage-gated potassium channel, Shab-family (KCNB, Kv2-like) alpha-subunit 0.0017 0.0019 0.0053
Brugia malayi intracellular kinase 0.005 0.0086 0.0238
Brugia malayi Smad1 0.0008 0.0002 0.0005
Schistosoma mansoni norepinephrine/norepinephrine transporter 0.0182 0.0356 0.0356
Echinococcus granulosus voltage gated sodium channel Nav1 alpha subunit 0.0017 0.0019 0.0053
Echinococcus granulosus glycogen synthase kinase 3 beta 0.005 0.0086 0.0238
Loa Loa (eye worm) hypothetical protein 0.0017 0.0019 0.0053
Trichomonas vaginalis ocrl type II inositol 5-phosphatase, putative 0.0008 0.0001 0.0012
Echinococcus granulosus potassium voltage gated channel subfamily H 0.0017 0.0019 0.0053
Echinococcus granulosus synaptojanin 1 0.0008 0.0001 0.0003
Brugia malayi MH2 domain containing protein 0.0008 0.0002 0.0005
Schistosoma mansoni hyperpolarization activated cyclic nucleotide-gated potassium channel 0.0017 0.0019 0.0019
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0016 0.0019 0.0189
Trypanosoma brucei apurinic/apyrimidinic endonuclease, putative 0.0038 0.0063 0.5237
Loa Loa (eye worm) hypothetical protein 0.0011 0.0007 0.002
Brugia malayi RNA binding protein 0.0065 0.0117 0.0323
Schistosoma mansoni cyclic-nucleotide-gated cation channel 0.0017 0.0019 0.0019
Loa Loa (eye worm) MH2 domain-containing protein 0.0008 0.0002 0.0005
Trichomonas vaginalis voltage and ligand gated potassium channel, putative 0.0017 0.0019 0.0195
Entamoeba histolytica inositol polyphosphate 5-phosphatase, putative 0.0008 0.0001 0.0097
Echinococcus granulosus diuretic hormone 44 receptor GPRdih2 0.0016 0.0018 0.005
Echinococcus granulosus ryanodine receptor 44f 0.0017 0.0019 0.0053
Schistosoma mansoni transient receptor potential cation channel subfamily A member 0.0816 0.1642 0.1642
Brugia malayi AMP-binding enzyme family protein 0.0024 0.0035 0.0096
Trichomonas vaginalis AGC family protein kinase 0.0066 0.012 0.1215
Loa Loa (eye worm) CXXC zinc finger family protein 0.003 0.0047 0.0131
Loa Loa (eye worm) hypothetical protein 0.0017 0.0019 0.0053
Loa Loa (eye worm) hypothetical protein 0.0011 0.0007 0.002
Leishmania major calcium channel protein, putative,ion transporter, putative 0.0017 0.0019 0.0815
Onchocerca volvulus 0.0008 0.0001 0.0012
Schistosoma mansoni serine/threonine protein kinase 0.0022 0.003 0.003
Brugia malayi ion channel NompC 0.0017 0.0019 0.0053
Loa Loa (eye worm) hypothetical protein 0.0017 0.0019 0.0053
Echinococcus multilocularis Protein kinase C, brain isozyme 0.0022 0.003 0.0084
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0016 0.0019 0.0189
Brugia malayi AMP-binding enzyme family protein 0.0024 0.0035 0.0096
Schistosoma mansoni sodium-dependent amino acid transporter 0.0031 0.0048 0.0048
Trypanosoma cruzi major cysteine proteinase, putative 0.0049 0.0085 0.7583
Brugia malayi Endonuclease/Exonuclease/phosphatase family protein 0.0008 0.0001 0.0003
Brugia malayi Nuclear hormone receptor family member nhr-19 0.0011 0.0007 0.002
Echinococcus granulosus potassium large conductance calcium activated 0.0017 0.0019 0.0053
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0016 0.0019 0.0189
Brugia malayi Papain family cysteine protease containing protein 0.0008 0.0003 0.0007
Echinococcus multilocularis DNA (apurinic or apyrimidinic site) lyase 0.0038 0.0063 0.0173
Brugia malayi MH1 domain containing protein 0.0008 0.0002 0.0005
Toxoplasma gondii endonuclease/exonuclease/phosphatase family protein 0.0008 0.0001 0.003
Schistosoma mansoni voltage-gated potassium channel 0.0017 0.0019 0.0019
Trypanosoma cruzi inositol 5-phosphatase 1, putative 0.0008 0.0001 0.0104
Trypanosoma cruzi apurinic/apyrimidinic endonuclease 0.0038 0.0063 0.5625
Entamoeba histolytica protein kinase, putative 0.005 0.0086 0.7195
Mycobacterium tuberculosis Probable fatty-acid-CoA ligase FadD2 (fatty-acid-CoA synthetase) (fatty-acid-CoA synthase) 0.0024 0.0035 0.1471
Plasmodium falciparum plasmepsin II 0.0198 0.0388 1
Echinococcus granulosus cathepsin l1 0.0016 0.0019 0.0052
Brugia malayi Voltage-gated calcium channel, alpha subunit 0.0017 0.0019 0.0053
Echinococcus granulosus nuclear receptor 2DBD gamma 0.0011 0.0007 0.002
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0011 0.0008 0.0078
Echinococcus granulosus potassium voltage gated channel protein 0.0017 0.0019 0.0053
Schistosoma mansoni tar DNA-binding protein 0.0065 0.0117 0.0117
Schistosoma mansoni SmCL2-like peptidase (C01 family) 0.0008 0.0003 0.0003
Brugia malayi hypothetical protein 0.0198 0.0388 0.1069
Schistosoma mansoni tar DNA-binding protein 0.0065 0.0117 0.0117
Brugia malayi Cathepsin L-like precursor 0.0011 0.0008 0.0021
Treponema pallidum exodeoxyribonuclease (exoA) 0.0038 0.0063 0.174
Trichomonas vaginalis Phospholipase C precursor, putative 0.0008 0.0001 0.0012
Trypanosoma cruzi Endonuclease/Exonuclease/phosphatase family, putative 0.0008 0.0001 0.0104
Echinococcus multilocularis potassium voltage gated channel subfamily D 0.0017 0.0019 0.0053
Trichomonas vaginalis AGC family protein kinase 0.0066 0.012 0.1215
Brugia malayi Eukaryotic aspartyl protease family protein 0.0198 0.0388 0.1069
Brugia malayi hypothetical protein 0.0017 0.0019 0.0053
Loa Loa (eye worm) hypothetical protein 0.0031 0.0048 0.0133
Echinococcus multilocularis ribosomal protein s6 kinase beta 1 0.0022 0.003 0.0084
Brugia malayi MH2 domain containing protein 0.0008 0.0002 0.0005
Brugia malayi Voltage-gated potassium channel, HERG (KCNH2)-related. C. elegans unc-103 ortholog 0.0017 0.0019 0.0053
Onchocerca volvulus 0.0016 0.0019 0.0189
Schistosoma mansoni smad1 5 8 and 0.0008 0.0002 0.0002
Echinococcus multilocularis FTZ F1 nuclear receptor protein 0.0011 0.0007 0.002
Brugia malayi Ligand-binding domain of nuclear hormone receptor family protein 0.0011 0.0007 0.002
Schistosoma mansoni hypothetical protein 0.0434 0.0866 0.0866
Leishmania major endonuclease/exonuclease protein-like protein 0.0008 0.0001 0.0049
Plasmodium falciparum RAC-beta serine/threonine protein kinase 0.0042 0.007 0.1813
Trichomonas vaginalis ap endonuclease, putative 0.0038 0.0063 0.0636
Entamoeba histolytica endonuclease/exonuclease/phosphatase domain containing protein 0.0008 0.0001 0.0097
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0016 0.0019 0.0189
Brugia malayi Voltage-gated potassium channel, KCNQ (Kv7-like) alpha-subunit. C. elegans kqt-1 ortholog 0.0017 0.0019 0.0053
Brugia malayi Voltage-gated calcium channel, L-type, alpha subunit. C. elegans egl-19 ortholog 0.0017 0.0019 0.0053
Entamoeba histolytica protein kinase, putative 0.0066 0.012 1
Entamoeba histolytica endonuclease/exonuclease/phosphatase family protein 0.0008 0.0001 0.0097
Entamoeba histolytica sphingomyelinase C precursor, putative 0.0008 0.0001 0.0097
Echinococcus multilocularis transient receptor potential cation channel 0.0017 0.0019 0.0053
Plasmodium vivax aspartyl proteinase, putative 0.0198 0.0388 1
Entamoeba histolytica cysteine protease, putative 0.0008 0.0003 0.0218
Schistosoma mansoni subfamily A1A unassigned peptidase (A01 family) 0.0198 0.0388 0.0388
Echinococcus granulosus inositol polyphosphate 5 phosphatase OCRL 1 0.0008 0.0001 0.0003
Trichomonas vaginalis Clan CA, family C1, papain-like cysteine peptidase 0.0016 0.0019 0.0189
Schistosoma mansoni voltage-dependent calcium channel 0.0017 0.0019 0.0019
Echinococcus multilocularis conserved hypothetical protein 0.0017 0.0019 0.0053
Schistosoma mansoni coup transcription factor 0.0011 0.0007 0.0007
Loa Loa (eye worm) RNA recognition domain-containing protein domain-containing protein 0.0065 0.0117 0.0323
Echinococcus granulosus nervana 2 0.004 0.0067 0.0185
Trichomonas vaginalis carbon catabolite repressor protein, putative 0.0008 0.0001 0.0012
Loa Loa (eye worm) hypothetical protein 0.0018 0.0022 0.0062
Mycobacterium tuberculosis Probable exodeoxyribonuclease III protein XthA (exonuclease III) (EXO III) (AP endonuclease VI) 0.0038 0.0063 0.266
Echinococcus multilocularis transfer RNA-Gly 0.0017 0.0019 0.0053
Echinococcus multilocularis serine:threonine protein kinase 38 0.0022 0.003 0.0084
Entamoeba histolytica protein kinase 2, putative 0.0042 0.007 0.5852
Brugia malayi Ryanodine Receptor TM 4-6 family protein 0.0017 0.0019 0.0053
Mycobacterium ulcerans fatty-acid-CoA ligase 0.0024 0.0035 0.0667
Echinococcus granulosus voltage dependent calcium channel 0.0017 0.0019 0.0053
Echinococcus granulosus potassium voltage gated channel subfamily A 0.0017 0.0019 0.0053
Trypanosoma cruzi cysteine peptidase, putative 0.0008 0.0003 0.0234
Leishmania major cathepsin L-like protease 0.0062 0.0112 0.4729
Brugia malayi Voltage-gated potassium channel, Shab-family (KCNB, Kv2-like) alpha-subunit. C. elegans exp-2 ortholog 0.0017 0.0019 0.0053
Loa Loa (eye worm) hypothetical protein 0.0017 0.0019 0.0053
Schistosoma mansoni thyroid hormone receptor 0.0011 0.0007 0.0007
Echinococcus multilocularis serine threonine protein kinase nrc serine threonine protein kinase gad 0.0042 0.007 0.0194
Brugia malayi Pre-SET motif family protein 0.0063 0.0113 0.0312
Brugia malayi Sodium:neurotransmitter symporter family protein 0.0031 0.0048 0.0133
Brugia malayi Corticotropin releasing factor receptor 2 precursor, putative 0.0051 0.0089 0.0245
Trypanosoma brucei Endonuclease/Exonuclease/phosphatase family, putative 0.0008 0.0001 0.0097
Echinococcus multilocularis histone lysine N methyltransferase MLL3 0.001 0.0006 0.0015
Echinococcus multilocularis ecdysone induced protein 78C 0.0011 0.0007 0.002
Echinococcus multilocularis voltage gated potassium channel 0.0017 0.0019 0.0053
Onchocerca volvulus 0.0031 0.0048 0.049
Echinococcus granulosus hyperpolarization activated cyclic 0.0017 0.0019 0.0053
Onchocerca volvulus 0.0016 0.0019 0.0189
Echinococcus multilocularis smad 0.0008 0.0002 0.0005
Loa Loa (eye worm) hypothetical protein 0.0008 0.0001 0.0003
Echinococcus granulosus Ribosomal protein S6 kinase beta 2 0.0022 0.003 0.0084
Brugia malayi Endonuclease/Exonuclease/phosphatase family protein 0.0008 0.0001 0.0003
Brugia malayi Endonuclease/Exonuclease/phosphatase family protein 0.0008 0.0001 0.0003
Schistosoma mansoni sodium/chloride dependent transporter 0.0031 0.0048 0.0048
Loa Loa (eye worm) Sodium:neurotransmitter symporter family protein 0.0031 0.0048 0.0133
Schistosoma mansoni serine/threonine-protein kinase 0.0046 0.0078 0.0078
Echinococcus granulosus histone lysine N methyltransferase MLL3 0.001 0.0006 0.0015
Onchocerca volvulus Transient receptor potential cation channel trpm homolog 0.0017 0.0019 0.0195
Echinococcus multilocularis sodium:chloride dependent neurotransmitter 0.0031 0.0048 0.0133
Plasmodium vivax plasmepsin IV, putative 0.0198 0.0388 1
Brugia malayi Endonuclease/Exonuclease/phosphatase family protein 0.0008 0.0001 0.0003
Schistosoma mansoni serine/threonine protein kinase 0.0022 0.003 0.003
Schistosoma mansoni serine/threonine kinase 0.0022 0.003 0.003
Trichomonas vaginalis Clan CA, family C1, papain-like cysteine peptidase 0.0016 0.0019 0.0189
Toxoplasma gondii aspartyl proteinase (eimepsin), putative 0.0198 0.0388 1
Brugia malayi Transient-receptor-potential like protein 0.0017 0.0019 0.0053
Schistosoma mansoni norepinephrine/norepinephrine transporter 0.0031 0.0048 0.0048
Echinococcus granulosus potassium voltage gated channel subfamily H 0.0017 0.0019 0.0053
Brugia malayi Papain family cysteine protease containing protein 0.0008 0.0003 0.0007
Plasmodium vivax rac-beta serine/threonine protein kinase, putative 0.0042 0.007 0.1813
Toxoplasma gondii aspartyl protease ASP1 0.0198 0.0388 1
Trichomonas vaginalis glucosylceramidase, putative 0.0274 0.0541 0.5477
Toxoplasma gondii aldehyde dehydrogenase 0.0124 0.0236 0.6097
Schistosoma mansoni serine/threonine protein kinase 0.0022 0.003 0.003
Schistosoma mansoni transient receptor potential cation channel subfamily m member 0.0017 0.0019 0.0019
Schistosoma mansoni thyroid hormone receptor 0.0011 0.0007 0.0007
Loa Loa (eye worm) exodeoxyribonuclease III family protein 0.0038 0.0063 0.0173
Brugia malayi Endonuclease/Exonuclease/phosphatase family protein 0.0008 0.0001 0.0003
Echinococcus multilocularis cyclic nucleotide gated cation channel alpha 3 0.0017 0.0019 0.0053
Toxoplasma gondii cathepsin CPL 0.0016 0.0019 0.0482
Schistosoma mansoni subfamily A1A unassigned peptidase (A01 family) 0.0198 0.0388 0.0388
Echinococcus multilocularis cathepsin l cysteine peptidase 0.0016 0.0019 0.0052
Echinococcus granulosus guanine nucleotide binding protein Gs subunit 0.0047 0.0081 0.0222
Trypanosoma cruzi apurinic/apyrimidinic endonuclease, putative 0.0008 0.0001 0.0104
Trichomonas vaginalis glucosylceramidase, putative 0.018 0.035 0.3543
Brugia malayi cation channel family protein 0.0017 0.0019 0.0053
Trichomonas vaginalis glucosylceramidase, putative 0.0274 0.0541 0.5477
Loa Loa (eye worm) hypothetical protein 0.0182 0.0356 0.0981
Loa Loa (eye worm) nuclear Hormone Receptor family member 0.0011 0.0007 0.002
Echinococcus granulosus aldehyde dehydrogenase mitochondrial 0.0124 0.0236 0.0652
Plasmodium falciparum transporter, putative 0.0031 0.0048 0.1249
Loa Loa (eye worm) histone methyltransferase 0.0012 0.0009 0.0026
Loa Loa (eye worm) voltage and ligand gated potassium channel 0.0017 0.0019 0.0053
Schistosoma mansoni aldehyde dehydrogenase 0.0124 0.0236 0.0236
Loa Loa (eye worm) hypothetical protein 0.0016 0.0018 0.005
Echinococcus multilocularis cathepsin L cysteine protease 0.0016 0.0019 0.0052
Echinococcus granulosus ecdysone induced protein 78C 0.0011 0.0007 0.002
Schistosoma mansoni TGF-beta signal transducer Smad2 0.0008 0.0002 0.0002
Trichomonas vaginalis serine/threonine-protein kinase sgk, putative 0.0021 0.0027 0.0275
Entamoeba histolytica cysteine protease, putative 0.0008 0.0003 0.0218
Mycobacterium tuberculosis Probable exported protein 0.0008 0.0001 0.0049
Loa Loa (eye worm) hypothetical protein 0.0182 0.0356 0.0981
Trypanosoma cruzi cysteine peptidase, clan CA, family C1, cathepsin L-like, putative 0.0057 0.0101 0.902
Echinococcus multilocularis geminin 0.0339 0.0673 0.1854
Loa Loa (eye worm) hypothetical protein 0.0008 0.0001 0.0003
Schistosoma mansoni hypothetical protein 0.0016 0.0018 0.0018
Loa Loa (eye worm) nuclear hormone receptor family member nhr-31 0.0011 0.0007 0.002
Onchocerca volvulus 0.0011 0.0007 0.0074
Toxoplasma gondii hypothetical protein 0.0017 0.0019 0.0497
Echinococcus multilocularis tar DNA binding protein 0.0065 0.0117 0.0323
Echinococcus multilocularis sodium and chloride dependent glycine 0.0031 0.0048 0.0133
Loa Loa (eye worm) voltage-gated potassium channel 0.0017 0.0019 0.0053
Echinococcus granulosus cyclic nucleotide gated cation channel alpha 3 0.0017 0.0019 0.0053
Onchocerca volvulus 0.0063 0.0113 0.1144
Schistosoma mansoni voltage-gated potassium channel 0.0017 0.0019 0.0019
Leishmania major inositol/phosphatidylinositol phosphatase, putative 0.0008 0.0001 0.0049
Mycobacterium ulcerans long-chain-fatty-acid-CoA ligase 0.0024 0.0035 0.0667
Schistosoma mansoni voltage-gated potassium channel 0.0017 0.0019 0.0019
Echinococcus multilocularis GPCR, family 2 0.0016 0.0018 0.005
Echinococcus granulosus cathepsin l cysteine peptidase 0.0016 0.0019 0.0052
Onchocerca volvulus 0.0031 0.0048 0.049
Schistosoma mansoni atypical protein kinase C 0.0022 0.003 0.003
Trichomonas vaginalis AGC family protein kinase 0.0022 0.003 0.0306
Schistosoma mansoni ryanodine receptor related 0.0017 0.0019 0.0019
Echinococcus granulosus cathepsin l1 0.0011 0.0008 0.0021
Echinococcus multilocularis ribosomal protein S6 kinase alpha 3 0.0022 0.003 0.0084
Loa Loa (eye worm) hypothetical protein 0.0011 0.0007 0.002
Treponema pallidum sodium- and chloride- dependent transporter 0.0182 0.0356 1
Toxoplasma gondii endonuclease/exonuclease/phosphatase family protein 0.0008 0.0001 0.003
Loa Loa (eye worm) hypothetical protein 0.0017 0.0019 0.0053
Echinococcus granulosus voltage gated potassium channel 0.0017 0.0019 0.0053
Trichomonas vaginalis Clan CA, family C1, papain-like cysteine peptidase 0.0016 0.0019 0.0189
Entamoeba histolytica endonuclease/exonuclease/phosphatase family protein 0.0008 0.0001 0.0097
Trypanosoma cruzi rac serine-threonine kinase, putative 0.0046 0.0078 0.7017
Mycobacterium ulcerans fatty-acid-CoA ligase 0.0018 0.0022 0.0428
Toxoplasma gondii cell-cycle-associated protein kinase GSK, putative 0.005 0.0086 0.2228
Brugia malayi Endonuclease/Exonuclease/phosphatase family protein 0.0008 0.0001 0.0003
Brugia malayi Sodium:neurotransmitter symporter family protein 1, putative 0.0031 0.0048 0.0133
Brugia malayi Endonuclease/Exonuclease/phosphatase family protein 0.0008 0.0001 0.0003
Loa Loa (eye worm) hypothetical protein 0.0016 0.0019 0.0052
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0008 0.0003 0.0218
Toxoplasma gondii 3'5'-cyclic nucleotide phosphodiesterase domain-containing protein 0.0017 0.0019 0.0497
Echinococcus granulosus sodium and chloride dependent glycine 0.0031 0.0048 0.0133
Schistosoma mansoni histone-lysine n-methyltransferase setb1 0.0063 0.0113 0.0113
Trichomonas vaginalis Clan CA, family C1, papain-like cysteine peptidase 0.0016 0.0019 0.0189
Schistosoma mansoni histone-lysine n-methyltransferase setb1 0.0063 0.0113 0.0113
Brugia malayi steroid hormone receptor 0.0011 0.0007 0.002
Echinococcus multilocularis sodium leak channel non selective protein 0.0017 0.0019 0.0053
Entamoeba histolytica cysteine proteinase, putative 0.0016 0.0019 0.1556
Trichomonas vaginalis glucosylceramidase, putative 0.0274 0.0541 0.5477
Loa Loa (eye worm) endonuclease/Exonuclease/phosphatase 0.0008 0.0001 0.0003
Echinococcus multilocularis calcium activated potassium channel 0.0018 0.0022 0.0062
Schistosoma mansoni aldehyde dehydrogenase 0.0124 0.0236 0.0236
Brugia malayi exodeoxyribonuclease III family protein 0.0038 0.0063 0.0173
Schistosoma mansoni serine/threonine protein kinase 0.0022 0.003 0.003
Echinococcus granulosus potassium voltage gated channel subfamily C 0.0017 0.0019 0.0053
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0062 0.0112 0.931
Schistosoma mansoni cpg binding protein 0.003 0.0047 0.0047
Echinococcus granulosus sodium leak channel non selective protein 0.0017 0.0019 0.0053
Brugia malayi hypothetical protein 0.0031 0.0048 0.0133
Toxoplasma gondii transporter, cation channel family protein 0.0017 0.0019 0.0497
Echinococcus granulosus 5'partial|histone lysine N methyltransferase SETDB2 0.006 0.0107 0.0295

Activities

No activities found for this compound.

Phenotypes

Whole-cell/tissue/organism interactions

We have no records of whole-cell/tissue assays done with this compound What does this mean?

Many chemical entities in TDR Targets come from high-throughput screenings with whole cells or tissue samples, and not all assayed compounds have been tested against a single a single target protein, probably because they get ruled out during screening process. Even if these compounds may have not been of interest in the original screening, they may come as interesting leads for other screening assays. Furthermore, we may be able to propose drug-target associations using chemical similarities and network patterns.

Annotated phenotypes:

We have no manually annotated phenotypes for this drug. What does this mean? / Care to help?
In TDR Targets, information about phenotypes that are caused by drugs, or by genetic manipulation of cells (e.g. gene knockouts or knockdowns) is manually curated from the literature. These descriptions help to describe the potential of the target for drug development. If no information is available for this gene or if the information is incomplete, this may mean that i) the papers containing this information either appeared after the curation effort for this organism was carried out or they were inadvertently missed by curators; or that ii) the curation effort for this organism has not yet started.
 
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External resources for this compound

Bibliographic References

No literature references available for this target.

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