Detailed information for compound 1987863

Basic information

Technical information
  • Name: Unnamed compound
  • MW: 679.603 | Formula: C33H39Cl2F3N6O2
  • H donors: 3 H acceptors: 3 LogP: 7.54 Rotable bonds: 11
    Rule of 5 violations (Lipinski): 2
  • SMILES: O=C(c1cc2nc(n(c2cc1N1CC2C(C1)C2)C)Nc1c(Cl)ccc(c1Cl)CNC(=O)C(C)(C)C)N[C@@H]1CC[C@H](CC1)C(F)(F)F
  • InChi: 1S/C33H39Cl2F3N6O2/c1-32(2,3)30(46)39-14-17-5-10-23(34)28(27(17)35)42-31-41-24-12-22(29(45)40-21-8-6-20(7-9-21)33(36,37)38)25(13-26(24)43(31)4)44-15-18-11-19(18)16-44/h5,10,12-13,18-21H,6-9,11,14-16H2,1-4H3,(H,39,46)(H,40,45)(H,41,42)/t18?,19?,20-,21-
  • InChiKey: QAMAGPZMSOZZRV-ZRPHKLAYSA-N  


Substructure search Similarity search

Network

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Synonyms

No synonyms found for this compound

Targets

Known targets for this compound

Species Target name Source Bibliographic reference
Homo sapiens prostaglandin E synthase Starlite/ChEMBL No references

Predicted pathogen targets for this compound

By orthology
Species Potential target Known druggable target/s Ortholog Group
Schistosoma japonicum ko:K00799 glutathione S-transferase [EC2.5.1.18], putative Get druggable targets OG5_131112 All targets in OG5_131112
Schistosoma japonicum ko:K00799 glutathione S-transferase [EC2.5.1.18], putative Get druggable targets OG5_131112 All targets in OG5_131112
Schistosoma mansoni membrane associated proteins in eicosanoid and glutathione metabolism family member Get druggable targets OG5_131112 All targets in OG5_131112
By sequence similarity to non orthologous known druggable targets
No druggable targets predicted by sequence similarity
Obtained from network model

Ranking Plot

Putative Targets List

Species Potential target Raw Global Species
Loa Loa (eye worm) hypothetical protein 0.0135 0.0346 0.0399
Loa Loa (eye worm) hypothetical protein 0.0052 0.0114 0.013
Schistosoma mansoni bromodomain containing protein 0.0106 0.0265 0.0274
Schistosoma mansoni microsomal glutathione s-transferase 0.0135 0.0345 0.0358
Trichomonas vaginalis adenylate and guanylate cyclases, putative 0.0016 0.0014 0.0052
Mycobacterium leprae conserved hypothetical protein 0.0131 0.0335 0.6672
Loa Loa (eye worm) kap beta 3 protein 0.0016 0.0013 0.0012
Echinococcus multilocularis g protein coupled receptor 0.0052 0.0114 0.0113
Loa Loa (eye worm) thioredoxin reductase 0.0075 0.0177 0.0203
Schistosoma mansoni hypothetical protein 0.0162 0.0419 0.0435
Loa Loa (eye worm) GTP-binding regulatory protein Gs alpha-S chain 0.0016 0.0013 0.0013
Trypanosoma cruzi trypanothione reductase, putative 0.0075 0.0177 0.526
Loa Loa (eye worm) nuclear Hormone Receptor family member 0.0013 0.0004 0.0002
Schistosoma mansoni zinc finger protein 0.0035 0.0066 0.0067
Trichomonas vaginalis chromobox protein, putative 0.0033 0.0059 0.0265
Plasmodium vivax dihydrolipoyl dehydrogenase, mitochondrial, putative 0.0026 0.004 0.1155
Loa Loa (eye worm) hypothetical protein 0.0052 0.0114 0.013
Trichomonas vaginalis CAMK family protein kinase 0.0127 0.0322 0.1503
Schistosoma mansoni myosin xvIII 0.0052 0.0114 0.0117
Giardia lamblia NADH oxidase lateral transfer candidate 0.0026 0.004 0.101
Chlamydia trachomatis arginine ABC transporter substrate-binding protein ArtJ 0.0014 0.0007 0.02
Schistosoma mansoni serine/threonine protein kinase 0.0127 0.0322 0.0334
Plasmodium falciparum thioredoxin reductase 0.0075 0.0177 0.8672
Brugia malayi hypothetical protein 0.0055 0.0121 0.0139
Trypanosoma cruzi PAB1-binding protein , putative 0.0065 0.015 0.446
Echinococcus multilocularis Basic leucine zipper (bZIP) transcription 0.0162 0.0419 0.0418
Loa Loa (eye worm) nuclear hormone receptor family member nhr-40 0.0013 0.0004 0.0002
Echinococcus multilocularis tyrosyl DNA phosphodiesterase 1 0.0049 0.0105 0.0103
Brugia malayi follicle stimulating hormone receptor 0.0052 0.0114 0.013
Leishmania major protein kinase, putative 0.0026 0.004 0.116
Mycobacterium leprae Probable fructose bisphosphate aldolase Fba 0.0058 0.0129 0.2459
Mycobacterium ulcerans error-prone DNA polymerase 0.0101 0.025 0.7439
Echinococcus multilocularis somatostatin receptor 0.0052 0.0114 0.0113
Echinococcus multilocularis g protein linked acetylcholine receptor gar 2a 0.0052 0.0114 0.0113
Onchocerca volvulus 0.0084 0.0203 0.0942
Onchocerca volvulus Cathepsin L homolog 0.0019 0.002 0.0081
Loa Loa (eye worm) hypothetical protein 0.0052 0.0114 0.013
Echinococcus multilocularis beta LACTamase domain containing family member 0.0131 0.0335 0.0333
Onchocerca volvulus Poor gastrulation protein homolog 0.0046 0.0096 0.044
Echinococcus multilocularis jumonji domain containing 1A 0.0016 0.0013 0.0012
Trypanosoma brucei DNA polymerase kappa, putative 0.0015 0.001 0.0261
Toxoplasma gondii histone lysine methyltransferase SET1 0.0047 0.0101 0.288
Echinococcus granulosus translational activator gcn1 0.0016 0.0013 0.0012
Schistosoma mansoni biogenic amine (dopamine) receptor 0.0052 0.0114 0.0117
Echinococcus granulosus neuropeptide Y receptor 0.0052 0.0114 0.0117
Echinococcus multilocularis neuropeptide Y receptor 0.0052 0.0114 0.0113
Leishmania major flap endonuclease-1 (FEN-1), putative 0.0018 0.0019 0.0525
Trichomonas vaginalis CAMK family protein kinase 0.0127 0.0322 0.1503
Echinococcus multilocularis Nuclear hormone receptor family member nhr 41 0.0013 0.0004 0.0002
Loa Loa (eye worm) hypothetical protein 0.0046 0.0096 0.011
Echinococcus granulosus biogenic amine 5HT receptor 0.0825 0.2271 0.2363
Loa Loa (eye worm) beta-lactamase 0.0131 0.0335 0.0386
Echinococcus multilocularis para nitrobenzyl esterase 0.0026 0.004 0.0039
Brugia malayi Thioredoxin reductase 0.0075 0.0177 0.0203
Loa Loa (eye worm) hypothetical protein 0.0029 0.005 0.0056
Schistosoma mansoni hypothetical protein 0.0052 0.0114 0.0117
Schistosoma mansoni biogenic amine (dopamine) receptor 0.0052 0.0114 0.0117
Loa Loa (eye worm) latrophilin receptor protein 2 0.0241 0.064 0.0741
Echinococcus multilocularis fetal alzheimer antigen, falz 0.0038 0.0074 0.0072
Loa Loa (eye worm) hypothetical protein 0.0052 0.0114 0.013
Trypanosoma cruzi tyrosyl-DNA Phosphodiesterase (Tdp1), putative 0.0049 0.0105 0.3101
Mycobacterium tuberculosis Probable thioesterase TesA 0.004 0.0081 0.0344
Onchocerca volvulus 0.0052 0.0114 0.0523
Brugia malayi Cathepsin L-like precursor 0.0019 0.002 0.0021
Schistosoma mansoni metabotropic glutamate receptor 0.024 0.0638 0.0662
Trypanosoma cruzi ISWI complex protein 0.0025 0.0038 0.1089
Brugia malayi jmjC domain containing protein 0.0016 0.0013 0.0013
Schistosoma mansoni hypothetical protein 0.0052 0.0114 0.0117
Loa Loa (eye worm) TK/ABL protein kinase 0.0149 0.0385 0.0445
Trichomonas vaginalis CAMK family protein kinase 0.0127 0.0322 0.1503
Mycobacterium tuberculosis NADPH-dependent mycothiol reductase Mtr 0.0075 0.0177 0.0761
Loa Loa (eye worm) hypothetical protein 0.0241 0.064 0.0741
Toxoplasma gondii type I fatty acid synthase, putative 0.0034 0.0064 0.1825
Schistosoma mansoni Tr4/Tr2 (homologue) 0.0013 0.0004 0.0002
Schistosoma mansoni microtubule-associated protein tau 0.2208 0.6134 0.6384
Onchocerca volvulus Metabotropic glutamate receptor homolog 0.0046 0.0096 0.044
Echinococcus granulosus tyrosine protein kinase Lyn 0.0016 0.0013 0.0012
Trichomonas vaginalis flap endonuclease-1, putative 0.0018 0.0019 0.0075
Leishmania major PAS-domain containing phosphoglycerate kinase, putative 0.0016 0.0014 0.0383
Trypanosoma brucei ISWI complex protein 0.0025 0.0038 0.1089
Brugia malayi putative neuropeptide receptor 0.0052 0.0114 0.013
Loa Loa (eye worm) hypothetical protein 0.0026 0.004 0.0045
Brugia malayi Nuclear hormone receptor family member nhr-19 0.0013 0.0004 0.0002
Brugia malayi TAR-binding protein 0.0123 0.0312 0.036
Brugia malayi Pre-SET motif family protein 0.0679 0.1863 0.2162
Trichomonas vaginalis adenylate cyclase, type VII, putative 0.0016 0.0014 0.0052
Brugia malayi PHD-finger family protein 0.0031 0.0053 0.006
Echinococcus multilocularis cathepsin L cysteine protease 0.0019 0.002 0.0019
Schistosoma mansoni transcription factor LCR-F1 0.0162 0.0419 0.0435
Loa Loa (eye worm) PHD-finger family protein 0.0031 0.0053 0.006
Wolbachia endosymbiont of Brugia malayi dihydrolipoamide dehydrogenase E3 component 0.0026 0.004 0.1552
Mycobacterium tuberculosis Probable multifunctional mycocerosic acid synthase membrane-associated Mas 0.0051 0.0111 0.0478
Toxoplasma gondii histone lysine methyltransferase SET/SUV39 0.0098 0.0241 0.6965
Mycobacterium tuberculosis Probable glutamine-binding lipoprotein GlnH (GLNBP) 0.0014 0.0007 0.0025
Plasmodium vivax vivapain-2 0.0019 0.002 0.0548
Echinococcus granulosus Smad4 0.0098 0.0241 0.025
Echinococcus multilocularis G-protein coupled receptor, putative 0.0052 0.0114 0.0113
Echinococcus granulosus neuropeptides capa receptor 0.0052 0.0114 0.0117
Loa Loa (eye worm) hypothetical protein 0.0031 0.0053 0.006
Leishmania major importin beta-1 subunit, putative 0.0068 0.0159 0.473
Onchocerca volvulus 0.0019 0.002 0.0081
Echinococcus granulosus flap endonuclease 1 0.0018 0.0019 0.0018
Schistosoma mansoni apoferritin-2 0.0015 0.0009 0.0008
Echinococcus granulosus retinoic acid receptor rxr beta a 0.0013 0.0004 0.0002
Schistosoma mansoni Smad4 0.0098 0.0241 0.025
Schistosoma mansoni chromobox protein 0.0054 0.0119 0.0123
Trypanosoma brucei DNA polymerase kappa, putative 0.0022 0.0029 0.0828
Trypanosoma cruzi GTP-binding nuclear protein rtb2, putative 0.0055 0.0121 0.3598
Onchocerca volvulus Neuropeptide F receptor homolog 0.0052 0.0114 0.0523
Brugia malayi Nuclear hormone receptor family member nhr-25 0.0013 0.0004 0.0002
Toxoplasma gondii PHD-finger domain-containing protein 0.0031 0.0053 0.1512
Mycobacterium tuberculosis Possible conserved lipoprotein LpqK 0.0131 0.0335 0.1445
Brugia malayi alpha keto acid dehydrogenase complex, E3 component, lipoamide dehydrogenase 0.0019 0.0021 0.0022
Echinococcus granulosus rhodopsin orphan GPCR 0.0052 0.0114 0.0117
Schistosoma mansoni Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) 0.0016 0.0013 0.0012
Trypanosoma cruzi cruzipain precursor, putative 0.0071 0.0167 0.4958
Schistosoma mansoni amine GPCR 0.0052 0.0114 0.0117
Loa Loa (eye worm) hypothetical protein 0.0052 0.0114 0.013
Loa Loa (eye worm) hypothetical protein 0.0013 0.0004 0.0002
Loa Loa (eye worm) melatonin receptor type 1A 0.0052 0.0114 0.013
Loa Loa (eye worm) hypothetical protein 0.0045 0.0094 0.0107
Schistosoma mansoni hypothetical protein 0.0241 0.064 0.0665
Loa Loa (eye worm) hypothetical protein 0.0052 0.0114 0.013
Echinococcus granulosus microsomal glutathione S transferase 3 0.0135 0.0345 0.0358
Echinococcus multilocularis dnaJ subfamily B 0.0286 0.0766 0.0764
Echinococcus granulosus neuropeptide receptor 0.0052 0.0114 0.0117
Schistosoma mansoni aryl hydrocarbon receptor 0.0017 0.0015 0.0014
Schistosoma mansoni adenoreceptor 0.0052 0.0114 0.0117
Loa Loa (eye worm) hypothetical protein 0.0032 0.0058 0.0064
Loa Loa (eye worm) jmjC domain-containing protein 0.0016 0.0013 0.0013
Schistosoma mansoni aryl hydrocarbon receptor nuclear translocator homolog (darnt) 0.0039 0.0076 0.0078
Echinococcus multilocularis guanine nucleotide binding protein G(s) subunit 0.0016 0.0013 0.0011
Trichomonas vaginalis chromodomain-helicase-DNA-binding protein, putative 0.0013 0.0006 0.0012
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0019 0.002 0.0081
Schistosoma mansoni peptide (FMRFamide/somatostatin)-like receptor 0.0052 0.0114 0.0117
Schistosoma mansoni smad 0.0098 0.0241 0.025
Plasmodium falciparum cysteine proteinase falcipain 3 0.0019 0.002 0.0932
Brugia malayi calcium-independent alpha-latrotoxin receptor 2, putative 0.0241 0.064 0.0741
Mycobacterium tuberculosis Probable hydrolase 0.0131 0.0335 0.1445
Loa Loa (eye worm) hypothetical protein 0.003 0.0053 0.0059
Loa Loa (eye worm) hypothetical protein 0.0052 0.0114 0.013
Onchocerca volvulus Atrial natriuretic peptide receptor 3 homolog 0.0032 0.0058 0.0257
Schistosoma mansoni smad1 5 8 and 0.0098 0.0241 0.025
Loa Loa (eye worm) nuclear hormone receptor family member nhr-41 0.0013 0.0004 0.0002
Mycobacterium ulcerans thioesterase 0.004 0.0081 0.2361
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0019 0.002 0.0081
Echinococcus multilocularis tachykinin peptides receptor 99D 0.0052 0.0114 0.0113
Schistosoma mansoni growth hormone secretagogue receptor 0.0052 0.0114 0.0117
Brugia malayi Guanylyl cyclase protein 23 0.0032 0.0058 0.0064
Brugia malayi MH1 domain containing protein 0.0054 0.0119 0.0136
Mycobacterium tuberculosis Probable polyketide synthase Pks15 0.002 0.0023 0.0094
Loa Loa (eye worm) hypothetical protein 0.0044 0.009 0.0102
Leishmania major cathepsin L-like protease 0.0019 0.002 0.0566
Onchocerca volvulus Protein ultraspiracle homolog 0.0013 0.0004 0.0003
Brugia malayi MH2 domain containing protein 0.0044 0.009 0.0102
Trichomonas vaginalis DNA polymerase IV / kappa, putative 0.0022 0.0029 0.0122
Schistosoma mansoni TGF-beta signal transducer Smad2 0.0098 0.0241 0.025
Trypanosoma brucei DNA polymerase kappa, putative 0.0022 0.0029 0.0828
Loa Loa (eye worm) hypothetical protein 0.0052 0.0114 0.013
Trypanosoma brucei dihydrolipoamide dehydrogenase 0.0026 0.004 0.1171
Echinococcus granulosus transportin 1 0.0016 0.0013 0.0012
Onchocerca volvulus 0.0052 0.0114 0.0523
Echinococcus granulosus para nitrobenzyl esterase 0.0026 0.004 0.0041
Mycobacterium tuberculosis Conserved protein 0.0131 0.0335 0.1445
Mycobacterium ulcerans hypothetical protein 0.0131 0.0335 1
Leishmania major cathepsin L-like protease 0.0071 0.0167 0.4958
Mycobacterium leprae DIHYDROLIPOAMIDE DEHYDROGENASE LPD (LIPOAMIDE REDUCTASE (NADH)) (LIPOYL DEHYDROGENASE) (DIHYDROLIPOYL DEHYDROGENASE) (DIAPHORASE 0.0189 0.0497 1
Trypanosoma cruzi DNA polymerase eta, putative 0.0022 0.0029 0.0828
Echinococcus multilocularis chromodomain helicase DNA binding protein 4 0.0013 0.0005 0.0003
Loa Loa (eye worm) hypothetical protein 0.0351 0.0948 0.1099
Schistosoma mansoni retinoid-x-receptor (RXR) 0.0013 0.0004 0.0002
Leishmania major DNA polymerase eta, putative 0.0022 0.0029 0.0828
Echinococcus granulosus neuroligin 0.0026 0.004 0.0041
Schistosoma mansoni smad1 5 8 and 0.0098 0.0241 0.025
Schistosoma mansoni steroid hormone receptor ad4bp 0.0013 0.0004 0.0002
Echinococcus multilocularis atrial natriuretic peptide receptor 0.0029 0.005 0.0049
Mycobacterium ulcerans phenolpthiocerol synthesis type-I polyketide synthase PpsC 0.0051 0.0111 0.3289
Echinococcus multilocularis mothers against decapentaplegic 6 0.0044 0.009 0.0089
Loa Loa (eye worm) hypothetical protein 0.0073 0.0171 0.0196
Brugia malayi putative neuropeptide receptor NPR1 0.0052 0.0114 0.013
Leishmania major extracellular receptor, putative 0.0029 0.005 0.1463
Trichomonas vaginalis penicillin-binding protein, putative 0.0131 0.0335 0.1563
Echinococcus multilocularis g protein coupled receptor 0.0052 0.0114 0.0113
Loa Loa (eye worm) hypothetical protein 0.0052 0.0114 0.013
Loa Loa (eye worm) hypothetical protein 0.0126 0.0319 0.0368
Schistosoma mansoni histone-lysine n-methyltransferase setb1 0.0126 0.0319 0.033
Trypanosoma cruzi DNA polymerase kappa, putative 0.0022 0.0029 0.0828
Trichomonas vaginalis CAMK family protein kinase 0.0127 0.0322 0.1503
Brugia malayi Cathepsin L-like precursor 0.0019 0.002 0.0021
Echinococcus granulosus mothers against decapentaplegic 2 0.0044 0.009 0.0093
Schistosoma mansoni RAR-like nuclear receptor 0.0013 0.0004 0.0002
Loa Loa (eye worm) hypothetical protein 0.0052 0.0114 0.013
Schistosoma mansoni opsin-like receptor 0.0052 0.0114 0.0117
Trichomonas vaginalis D-aminoacylase, putative 0.0131 0.0335 0.1563
Onchocerca volvulus 0.0131 0.0335 0.1563
Loa Loa (eye worm) G-protein-linked acetylcholine receptor protein 2 0.0052 0.0114 0.013
Trichomonas vaginalis conserved hypothetical protein 0.0016 0.0014 0.0052
Onchocerca volvulus 0.0019 0.002 0.0081
Schistosoma mansoni hypothetical protein 0.3452 0.9607 1
Schistosoma mansoni nuclear hormone receptor 0.0013 0.0004 0.0002
Loa Loa (eye worm) hypothetical protein 0.0052 0.0114 0.013
Trypanosoma cruzi ISWI complex protein 0.0025 0.0038 0.1089
Schistosoma mansoni histone-lysine n-methyltransferase suv9 0.0107 0.0266 0.0275
Plasmodium falciparum cysteine proteinase falcipain 2a 0.0019 0.002 0.0932
Brugia malayi acetyltransferase, GNAT family protein 0.0084 0.0203 0.0234
Brugia malayi GTP-binding regulatory protein Gs alpha-S chain, putative 0.0016 0.0013 0.0013
Onchocerca volvulus 0.0026 0.004 0.0176
Brugia malayi PHD-finger family protein 0.0014 0.0008 0.0007
Echinococcus multilocularis chromobox protein 1 0.0054 0.0119 0.0118
Echinococcus granulosus Nuclear hormone receptor family member nhr 41 0.0013 0.0004 0.0002
Brugia malayi Protein kinase domain containing protein 0.011 0.0274 0.0316
Schistosoma mansoni importin beta-1 0.0084 0.0204 0.0211
Loa Loa (eye worm) hypothetical protein 0.0084 0.0204 0.0234
Mycobacterium tuberculosis Probable polyketide synthase Pks1 0.0035 0.0065 0.0277
Trichomonas vaginalis Clan CA, family C1, papain-like cysteine peptidase 0.0019 0.002 0.0081
Schistosoma mansoni jumonji/arid domain-containing protein 0.0065 0.015 0.0154
Loa Loa (eye worm) MH2 domain-containing protein 0.0044 0.009 0.0102
Echinococcus granulosus Basic leucine zipper bZIP transcription 0.0162 0.0419 0.0435
Loa Loa (eye worm) 5-hydroxytryptamine 2C receptor 0.0052 0.0114 0.013
Brugia malayi beta-lactamase family protein 0.0131 0.0335 0.0386
Trichomonas vaginalis guanylate cyclase, putative 0.0016 0.0014 0.0052
Onchocerca volvulus 0.0019 0.002 0.0081
Brugia malayi Carboxylesterase family protein 0.0026 0.004 0.0045
Echinococcus granulosus snurportin 1 0.09 0.2482 0.2582
Trichomonas vaginalis fructose-bisphosphate aldolase, putative 0.0118 0.0298 0.1389
Echinococcus granulosus rhodopsin orphan GPCR 0.0052 0.0114 0.0117
Loa Loa (eye worm) hypothetical protein 0.0052 0.0114 0.013
Schistosoma mansoni photoreceptor-specific nuclear receptor related 0.0013 0.0004 0.0002
Mycobacterium ulcerans phenolpthiocerol synthesis type-I polyketide synthase PpsD 0.0048 0.0103 0.3037
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0052 0.0114 0.0117
Trypanosoma brucei JmjC domain, hydroxylase, putative 0.0016 0.0013 0.0359
Echinococcus granulosus glutamate receptor ionotrophic AMPA 3 0.0035 0.0065 0.0067
Loa Loa (eye worm) hypothetical protein 0.0024 0.0035 0.0038
Loa Loa (eye worm) gonadotropin-releasing hormone receptor 2 0.0052 0.0114 0.013
Mycobacterium tuberculosis Polyketide synthetase MbtD (polyketide synthase) 0.0015 0.001 0.0037
Loa Loa (eye worm) hypothetical protein 0.0052 0.0114 0.013
Plasmodium falciparum phd finger protein, putative 0.0031 0.0053 0.2572
Plasmodium vivax transportin, putative 0.0016 0.0013 0.0321
Mycobacterium tuberculosis POSSIBLE PARA-NITROBENZYL ESTERASE (FRAGMENT) 0.0026 0.004 0.017
Mycobacterium ulcerans Type I modular polyketide synthase 0.0048 0.0103 0.3037
Loa Loa (eye worm) hypothetical protein 0.0131 0.0335 0.0386
Schistosoma mansoni cellular tumor antigen P53 0.0135 0.0346 0.0358
Leishmania major protein kinase, putative 0.0026 0.004 0.116
Mycobacterium ulcerans thioesterase TesA 0.004 0.0081 0.2361
Schistosoma mansoni tar DNA-binding protein 0.0123 0.0312 0.0323
Trypanosoma brucei dihydrolipoamide dehydrogenase 0.0026 0.004 0.1171
Loa Loa (eye worm) hypothetical protein 0.0012 0.0003 0.0001
Plasmodium falciparum histone acetyltransferase GCN5 0.0022 0.0029 0.1347
Schistosoma mansoni chromobox protein 0.0054 0.0119 0.0123
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0071 0.0167 0.4958
Brugia malayi hypothetical protein 0.0162 0.0419 0.0484
Onchocerca volvulus 0.0019 0.002 0.0081
Trichomonas vaginalis fructose-bisphosphate aldolase, putative 0.0118 0.0298 0.1389
Brugia malayi MH2 domain containing protein 0.0098 0.0241 0.0278
Brugia malayi hypothetical protein 0.0052 0.0114 0.013
Echinococcus multilocularis importin 5 0.0016 0.0013 0.0011
Onchocerca volvulus 0.0026 0.004 0.0176
Echinococcus granulosus dual specificity 0.011 0.0274 0.0284
Echinococcus granulosus tyrosine protein kinase ABL1 0.0149 0.0385 0.04
Brugia malayi Cathepsin L-like precursor 0.0012 0.0003 0.0001
Loa Loa (eye worm) nuclear hormone receptor family member nhr-14 0.0013 0.0004 0.0002
Echinococcus multilocularis neuroligin 0.0026 0.004 0.0039
Echinococcus multilocularis conserved hypothetical protein 0.0779 0.2144 0.2143
Echinococcus multilocularis ferritin 0.0015 0.0009 0.0008
Onchocerca volvulus 0.0383 0.1037 0.4874
Mycobacterium leprae PHENOLPTHIOCEROL SYNTHESIS TYPE-I POLYKETIDE SYNTHASE PPSA 0.0048 0.0103 0.1924
Loa Loa (eye worm) nuclear hormone receptor family member nhr-31 0.0013 0.0004 0.0002
Echinococcus multilocularis Glutamate receptor, ionotropic kainate 2 0.0035 0.0065 0.0064
Mycobacterium tuberculosis Carboxylesterase LipT 0.0026 0.004 0.017
Schistosoma mansoni biogenic amine (dopamine) receptor 0.0052 0.0114 0.0117
Mycobacterium leprae PROBABLE THIOESTERASE TESA 0.004 0.0081 0.1463
Trichomonas vaginalis Clan CA, family C1, papain-like cysteine peptidase 0.0019 0.002 0.0081
Loa Loa (eye worm) hypothetical protein 0.0131 0.0335 0.0386
Entamoeba histolytica hypothetical protein 0.0162 0.0419 1
Mycobacterium tuberculosis Conserved hypothetical protein 0.0022 0.0029 0.0121
Brugia malayi Bromodomain containing protein 0.0036 0.007 0.0079
Trichomonas vaginalis CAMK family protein kinase 0.0067 0.0156 0.072
Loa Loa (eye worm) follicle stimulating hormone receptor 0.0052 0.0114 0.013
Trypanosoma cruzi dihydrolipoamide dehydrogenase, putative 0.0026 0.004 0.1171
Chlamydia trachomatis two component regulatory system sensor histidine kinase 0.0016 0.0014 0.0491
Loa Loa (eye worm) hypothetical protein 0.0052 0.0114 0.013
Loa Loa (eye worm) hypothetical protein 0.0026 0.004 0.0045
Loa Loa (eye worm) hypothetical protein 0.0052 0.0114 0.013
Onchocerca volvulus Mothers against decapentaplegic homolog 0.0044 0.009 0.0411
Leishmania major cysteine peptidase A (CPA) 0.0019 0.002 0.0566
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0019 0.002 0.0081
Echinococcus granulosus dnaJ subfamily B 0.0286 0.0766 0.0796
Loa Loa (eye worm) glutathione reductase 0.0075 0.0177 0.0203
Mycobacterium tuberculosis Phenolpthiocerol synthesis type-I polyketide synthase PpsD 0.0048 0.0103 0.0442
Echinococcus granulosus dna polymerase eta 0.0022 0.0029 0.0029
Loa Loa (eye worm) hypothetical protein 0.0052 0.0114 0.013
Schistosoma mansoni peptide (allatostatin/somatostatin)-like receptor 0.0052 0.0114 0.0117
Trichomonas vaginalis CAMK family protein kinase 0.0127 0.0322 0.1503
Echinococcus multilocularis dna polymerase eta 0.0022 0.0029 0.0028
Echinococcus multilocularis neuropeptides capa receptor 0.0052 0.0114 0.0113
Echinococcus multilocularis dro:myosuppressin receptor 0.0052 0.0114 0.0113
Echinococcus granulosus rhodopsin orphan GPCR 0.0052 0.0114 0.0117
Echinococcus multilocularis Ataxin 2, N terminal,domain containing protein 0.0029 0.005 0.0048
Brugia malayi Kinesin motor domain containing protein 0.0016 0.0011 0.0011
Toxoplasma gondii PHD-finger domain-containing protein 0.0031 0.0053 0.1512
Trypanosoma brucei unspecified product 0.0015 0.001 0.0261
Loa Loa (eye worm) PHD-finger family protein 0.0034 0.0062 0.007
Loa Loa (eye worm) hypothetical protein 0.0052 0.0114 0.013
Onchocerca volvulus Dopamine\/Ecdysteroid receptor homolog 0.0052 0.0114 0.0523
Plasmodium falciparum ataxin-2 like protein, putative 0.0065 0.015 0.7353
Plasmodium falciparum importin beta, putative 0.0084 0.0204 1
Echinococcus granulosus GPCR family 2 0.0241 0.064 0.0665
Echinococcus multilocularis thyrotropin releasing hormone receptor 0.0052 0.0114 0.0113
Brugia malayi Nuclear hormone receptor family member nhr-25 0.0013 0.0004 0.0002
Schistosoma mansoni bromodomain-containing nuclear protein 1 brd1 0.0031 0.0053 0.0054
Brugia malayi Methyltransferase-like protein 4 0.0015 0.0009 0.0008
Trypanosoma brucei unspecified product 0.0015 0.001 0.0261
Loa Loa (eye worm) CXXC zinc finger family protein 0.002 0.0024 0.0026
Echinococcus granulosus chromobox protein 1 0.0054 0.0119 0.0123
Echinococcus multilocularis tm gpcr rhodopsin gpcr rhodopsin superfamily 0.0052 0.0114 0.0113
Trichomonas vaginalis chromobox protein, putative 0.0054 0.0119 0.0548
Trypanosoma cruzi hypothetical protein, conserved 0.0131 0.0335 1
Brugia malayi mothers against decapentaplegic homolog 3 0.0044 0.009 0.0102
Trichomonas vaginalis CAMK family protein kinase 0.0127 0.0322 0.1503
Loa Loa (eye worm) hypothetical protein 0.0045 0.0094 0.0107
Giardia lamblia Histone acetyltransferase GCN5 0.0022 0.0029 0.0633
Brugia malayi Cathepsin L-like precursor 0.0019 0.002 0.0021
Loa Loa (eye worm) hypothetical protein 0.0131 0.0335 0.0386
Loa Loa (eye worm) hypothetical protein 0.0012 0.0003 0.0001
Entamoeba histolytica cysteine proteinase, putative 0.0012 0.0003 0.0073
Mycobacterium tuberculosis Probable bacterioferritin BfrA 0.0015 0.0009 0.0035
Echinococcus granulosus hepatocyte nuclear factor 4 alpha 0.0013 0.0004 0.0002
Brugia malayi Hypothetical 52.5 kDa protein ZK945.1 in chromosome II, putative 0.0131 0.0335 0.0386
Schistosoma mansoni serine/threonine protein kinase 0.3096 0.8612 0.8964
Echinococcus multilocularis rhodopsin orphan GPCR 0.0052 0.0114 0.0113
Brugia malayi Heterochromatin protein 1 0.0054 0.0119 0.0136
Trypanosoma brucei tyrosyl-DNA Phosphodiesterase (Tdp1), putative 0.0049 0.0105 0.3101
Loa Loa (eye worm) hypothetical protein 0.0052 0.0114 0.013
Brugia malayi Dopamine receptor protein 1, putative (partial) 0.0052 0.0114 0.013
Toxoplasma gondii histone lysine demethylase JMJD6a 0.0016 0.0013 0.0348
Loa Loa (eye worm) hypothetical protein 0.0029 0.005 0.0056
Echinococcus multilocularis neuropeptide receptor 0.0052 0.0114 0.0113
Schistosoma mansoni terminal deoxycytidyl transferase 0.0022 0.0029 0.0029
Schistosoma mansoni apoferritin-2 0.0015 0.0009 0.0008
Echinococcus granulosus transcription factor Dp 1 0.0028 0.0047 0.0048
Plasmodium falciparum glutathione reductase 0.0075 0.0177 0.8672
Echinococcus multilocularis receptor type guanylyl cyclase 0.0032 0.0058 0.0056
Echinococcus multilocularis phd:f box containing protein 0.0016 0.0013 0.0012
Leishmania major DNA polymerase kappa, putative 0.0022 0.0029 0.0828
Entamoeba histolytica hypothetical protein 0.0162 0.0419 1
Trypanosoma cruzi cysteine peptidase, putative 0.0071 0.0167 0.4958
Echinococcus granulosus tm gpcr rhodopsin 0.0052 0.0114 0.0117
Toxoplasma gondii 3-oxoacyl-acyl-carrier protein synthase I/II, putative 0.0012 0.0002 0.0018
Trichomonas vaginalis Clan CA, family C1, papain-like cysteine peptidase 0.0019 0.002 0.0081
Echinococcus multilocularis rhodopsin orphan GPCR 0.0052 0.0114 0.0113
Brugia malayi sulfakinin receptor protein 0.0052 0.0114 0.013
Echinococcus multilocularis lysine specific demethylase 5A 0.0061 0.0138 0.0136
Loa Loa (eye worm) hypothetical protein 0.0054 0.0119 0.0136
Loa Loa (eye worm) hypothetical protein 0.0153 0.0396 0.0457
Trichomonas vaginalis soluble guanylate cyclase gcy, putative 0.0016 0.0014 0.0052
Echinococcus granulosus mothers against decapentaplegic 6 0.0044 0.009 0.0093
Trichomonas vaginalis set domain proteins, putative 0.0772 0.2125 1
Mycobacterium leprae PROBABLE NADH DEHYDROGENASE NDH 0.017 0.0444 0.8912
Trypanosoma brucei DNA polymerase IV, putative 0.0022 0.0029 0.0828
Brugia malayi metabotropic glutamate receptor subtype 5a (mGluR5a), putative 0.0256 0.0684 0.0792
Leishmania major cathepsin L-like protease 0.0019 0.002 0.0566
Loa Loa (eye worm) hypothetical protein 0.0052 0.0114 0.013
Schistosoma mansoni FTZ-F1 nuclear receptor-like protein 0.0013 0.0004 0.0002
Mycobacterium ulcerans polyketide synthase 0.0048 0.0103 0.3037
Echinococcus multilocularis gcn5proteinral control of amino acid synthesis 0.0084 0.0203 0.0202
Echinococcus granulosus metabotropic glutamate receptor 5 0.0351 0.0948 0.0986
Schistosoma mansoni nuclear hormone receptor nor-1/nor-2 0.0013 0.0004 0.0002
Echinococcus granulosus peregrin 0.0036 0.007 0.0071
Schistosoma mansoni metabotropic glutamate receptor 2 3 (mglur group 2) 0.0322 0.0866 0.09
Echinococcus multilocularis growth hormone secretagogue receptor type 1 0.0052 0.0114 0.0113
Trichomonas vaginalis Clan CA, family C1, papain-like cysteine peptidase 0.0019 0.002 0.0081
Loa Loa (eye worm) RGC/RGC protein kinase 0.0032 0.0058 0.0064
Echinococcus multilocularis neuropeptide receptor 0.0052 0.0114 0.0113
Loa Loa (eye worm) hypothetical protein 0.0016 0.0013 0.0013
Echinococcus granulosus guanine nucleotide binding protein Gs subunit 0.0016 0.0013 0.0012
Brugia malayi Carboxylesterase family protein 0.0026 0.004 0.0045
Echinococcus multilocularis thyroid hormone receptor alpha 0.0013 0.0004 0.0002
Brugia malayi chromobox protein homolog 3 0.003 0.0053 0.0059
Loa Loa (eye worm) hypothetical protein 0.0038 0.0075 0.0085
Loa Loa (eye worm) hypothetical protein 0.0052 0.0114 0.013
Leishmania major cathepsin L-like protease 0.0019 0.002 0.0566
Loa Loa (eye worm) G-protein coupled receptor 0.0052 0.0114 0.013
Echinococcus multilocularis Glutamate receptor, ionotropic kainate 2 0.0035 0.0065 0.0064
Schistosoma mansoni amine GPCR 0.0052 0.0114 0.0117
Mycobacterium ulcerans esterase/lipase LipP 0.0131 0.0335 1
Loa Loa (eye worm) hypothetical protein 0.0052 0.0114 0.013
Plasmodium vivax dihydrolipoyl dehydrogenase, apicoplast, putative 0.0026 0.004 0.1155
Echinococcus multilocularis glutamate receptor 2 0.0029 0.005 0.0049
Loa Loa (eye worm) hypothetical protein 0.0052 0.0114 0.013
Schistosoma mansoni ancient conserved domain protein 2 (cyclin m2) 0.0052 0.0114 0.0117
Onchocerca volvulus 0.0772 0.2125 1
Echinococcus granulosus g protein coupled receptor 0.0052 0.0114 0.0117
Onchocerca volvulus 0.0019 0.002 0.0081
Schistosoma mansoni ferritin 0.0015 0.0009 0.0008
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0071 0.0167 0.4958
Echinococcus granulosus neuropeptide s receptor 0.0052 0.0114 0.0117
Entamoeba histolytica protein kinase, putative 0.011 0.0274 0.6539
Schistosoma mansoni tyrosine kinase 0.0147 0.0379 0.0393
Echinococcus multilocularis serotonin receptor 0.0052 0.0114 0.0113
Trichomonas vaginalis adenylate cyclase, putative 0.0016 0.0014 0.0052
Brugia malayi RE15519p 0.0052 0.0114 0.013
Echinococcus granulosus guanine nucleotide binding protein Gs subunit 0.0016 0.0013 0.0012
Echinococcus multilocularis acetylcholinesterase 0.0153 0.0396 0.0394
Trypanosoma brucei DNA polymerase kappa, putative 0.0015 0.001 0.0261
Onchocerca volvulus 0.0052 0.0114 0.0523
Echinococcus granulosus microtubule associated protein 2 0.2208 0.6134 0.6384
Brugia malayi jmjC domain containing protein 0.0065 0.015 0.0171
Brugia malayi Nuclear hormone receptor family member nhr-31 0.0013 0.0004 0.0002
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0019 0.002 0.0081
Loa Loa (eye worm) MH1 domain-containing protein 0.0044 0.009 0.0102
Echinococcus multilocularis g-protein coupled receptor 0.0052 0.0114 0.0113
Trypanosoma brucei dihydrolipoamide dehydrogenase, point mutation 0.0026 0.004 0.1171
Schistosoma mansoni survival motor neuron protein 0.0028 0.0046 0.0047
Onchocerca volvulus 0.0045 0.0094 0.043
Trichomonas vaginalis fructose-bisphosphate aldolase, putative 0.0118 0.0298 0.1389
Trypanosoma cruzi dihydrolipoyl dehydrogenase, putative 0.0026 0.004 0.1171
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0071 0.0167 0.4958
Onchocerca volvulus 0.002 0.0024 0.0099
Schistosoma mansoni hypothetical protein 0.0052 0.0114 0.0117
Echinococcus multilocularis histone lysine methyltransferase setb histone lysine methyltransferase eggless 0.0126 0.0319 0.0317
Schistosoma mansoni 3-oxoacyl-[ACP] synthase 0.0012 0.0002 0.0001
Brugia malayi hypothetical protein 0.0052 0.0114 0.013
Loa Loa (eye worm) metabotropic glutamate receptor 8 0.0029 0.005 0.0056
Onchocerca volvulus 0.0052 0.0114 0.0523
Echinococcus granulosus tyrosine kinase 0.0032 0.0058 0.0058
Plasmodium vivax kinesin-5 0.0016 0.0011 0.0283
Echinococcus multilocularis bromodomain adjacent to zinc finger domain 0.0059 0.0132 0.013
Entamoeba histolytica hypothetical protein 0.0162 0.0419 1
Plasmodium vivax vivapain-2 0.0019 0.002 0.0548
Echinococcus granulosus serine:threonine protein kinase PLK1 0.0127 0.0322 0.0334
Echinococcus granulosus growth hormone secretagogue receptor type 1 0.0052 0.0114 0.0117
Brugia malayi ImpB/MucB/SamB family protein 0.0022 0.0029 0.0031
Echinococcus granulosus cpg binding protein 0.0024 0.0036 0.0036
Echinococcus multilocularis kinesin family 1 0.0119 0.0301 0.03
Trichomonas vaginalis conserved hypothetical protein 0.003 0.0053 0.0235
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0071 0.0167 0.4958
Entamoeba histolytica protein kinase, putative 0.011 0.0274 0.6539
Entamoeba histolytica HEAT repeat domain containing protein 0.0016 0.0013 0.0303
Echinococcus multilocularis neuropeptide FF receptor 2 0.0052 0.0114 0.0113
Plasmodium vivax ataxin-2 like protein, putative 0.0065 0.015 0.445
Echinococcus multilocularis FTZ F1 alpha 0.0013 0.0004 0.0002
Echinococcus multilocularis G protein coupled receptor 139 0.0052 0.0114 0.0113
Echinococcus multilocularis survival motor neuron protein 1 0.0137 0.0352 0.035
Loa Loa (eye worm) nuclear factor I 0.0054 0.0119 0.0136
Trichomonas vaginalis CAMK family protein kinase 0.0067 0.0156 0.072
Echinococcus granulosus rhodopsin orphan GPCR 0.0052 0.0114 0.0117
Echinococcus granulosus PHD finger protein rhinoceros 0.0031 0.0053 0.0054
Loa Loa (eye worm) hypothetical protein 0.0052 0.0114 0.013
Brugia malayi latrophilin 2 splice variant baaae 0.052 0.142 0.1646
Onchocerca volvulus 0.0052 0.0114 0.0523
Schistosoma mansoni hypothetical protein 0.0025 0.0038 0.0038
Onchocerca volvulus Protein cycle homolog 0.0039 0.0076 0.0344
Loa Loa (eye worm) hypothetical protein 0.0131 0.0335 0.0386
Onchocerca volvulus 0.0028 0.0046 0.0204
Echinococcus granulosus serotonin receptor 0.0052 0.0114 0.0117
Brugia malayi Nuclear hormone receptor-like 1 0.0013 0.0004 0.0002
Echinococcus granulosus BC026374 protein S09 family 0.0026 0.004 0.0041
Loa Loa (eye worm) hypothetical protein 0.01 0.0248 0.0286
Trichomonas vaginalis conserved hypothetical protein 0.003 0.0053 0.0235
Loa Loa (eye worm) hypothetical protein 0.0052 0.0114 0.013
Trichomonas vaginalis DNA polymerase eta, putative 0.0022 0.0029 0.0122
Schistosoma mansoni DNA polymerase eta 0.0022 0.0029 0.0029
Loa Loa (eye worm) hypothetical protein 0.0013 0.0004 0.0002
Mycobacterium leprae Possible regulatory protein 0.0016 0.0014 0.0102
Echinococcus multilocularis neuropeptide s receptor 0.0052 0.0114 0.0113
Brugia malayi Carboxylesterase family protein 0.0026 0.004 0.0045
Mycobacterium tuberculosis Probable membrane bound polyketide synthase Pks6 0.0072 0.017 0.0731
Echinococcus multilocularis hepatocyte nuclear factor 4 alpha 0.0013 0.0004 0.0002
Schistosoma mansoni peptide (FMRFamide/neurokinin-3)-like receptor 0.0052 0.0114 0.0117
Schistosoma mansoni Smad4 0.0044 0.009 0.0093
Brugia malayi hypothetical protein 0.0052 0.0114 0.013
Loa Loa (eye worm) hypothetical protein 0.0052 0.0114 0.013
Loa Loa (eye worm) RNA binding protein 0.0123 0.0312 0.036
Echinococcus granulosus neuropeptide receptor 0.0052 0.0114 0.0117
Echinococcus granulosus importin subunit beta 1 0.0084 0.0204 0.0211
Loa Loa (eye worm) hypothetical protein 0.0052 0.0114 0.013
Mycobacterium ulcerans multifunctional mycocerosic acid synthase membrane-associated Mas 0.0051 0.0111 0.3289
Echinococcus multilocularis FTZ F1 nuclear receptor protein 0.0013 0.0004 0.0002
Trypanosoma brucei dihydrolipoyl dehydrogenase 0.0026 0.004 0.1171
Echinococcus granulosus MAP kinase activated protein kinase 2 0.3096 0.8612 0.8964
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0019 0.002 0.0081
Brugia malayi G protein-coupled receptor F59B2.13 0.0052 0.0114 0.013
Mycobacterium tuberculosis Probable lipase LipE 0.0131 0.0335 0.1445
Onchocerca volvulus 0.0055 0.0121 0.0558
Schistosoma mansoni zinc finger protein 0.0025 0.0038 0.0038
Echinococcus granulosus aryl hydrocarbon receptor 0.0055 0.0122 0.0126
Loa Loa (eye worm) hypothetical protein 0.0052 0.0114 0.013
Trichomonas vaginalis chromodomain helicase DNA binding protein, putative 0.0013 0.0006 0.0012
Giardia lamblia PHD finger protein 15 0.0031 0.0053 0.1425
Schistosoma mansoni BC026374 protein (S09 family) 0.0026 0.004 0.0041
Loa Loa (eye worm) hypothetical protein 0.0052 0.0114 0.013
Onchocerca volvulus 0.0052 0.0114 0.0523
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0019 0.002 0.0081
Mycobacterium ulcerans phenolpthiocerol synthesis type-I polyketide synthase PpsB 0.0039 0.0077 0.2245
Brugia malayi dihydrolipoyl dehydrogenase, mitochondrial precursor, putative 0.0026 0.004 0.0045
Trypanosoma brucei PAB1-binding protein , putative 0.0065 0.015 0.446
Echinococcus multilocularis pyroglutamylated rfamide peptide receptor 0.0052 0.0114 0.0113
Echinococcus granulosus bromodomain adjacent to zinc finger domain 0.01 0.0248 0.0257
Echinococcus granulosus ecdysone induced protein 78C 0.0013 0.0004 0.0002
Onchocerca volvulus Heterochromatin protein 1 homolog 0.0033 0.0059 0.0265
Schistosoma mansoni muscarinic acetylcholine (GAR) receptor 0.0052 0.0114 0.0117
Trichomonas vaginalis chromodomain helicase DNA binding protein, putative 0.0013 0.0006 0.0012
Plasmodium vivax hypothetical protein, conserved 0.0131 0.0335 1
Brugia malayi hypothetical protein 0.0052 0.0114 0.013
Trypanosoma brucei DNA polymerase IV, putative 0.0022 0.0029 0.0828
Trichomonas vaginalis chromodomain helicase DNA binding protein, putative 0.0013 0.0006 0.0012
Trypanosoma brucei polo-like protein kinase 0.0127 0.0322 0.9618
Trypanosoma brucei DNA polymerase kappa, putative 0.0022 0.0029 0.0828
Trichomonas vaginalis guanylate cyclase, putative 0.0016 0.0014 0.0052
Leishmania major cathepsin L-like protease 0.0019 0.002 0.0566
Mycobacterium leprae PROBABLE FATTY ACID SYNTHASE FAS (FATTY ACID SYNTHETASE) 0.0015 0.0011 0.0027
Echinococcus granulosus dna polymerase kappa 0.0022 0.0029 0.0029
Echinococcus granulosus tachykinin peptides receptor 99D 0.0052 0.0114 0.0117
Onchocerca volvulus 0.0019 0.002 0.0081
Echinococcus granulosus Jumonji AT rich interactive domain 1B 0.002 0.0025 0.0025
Schistosoma mansoni acetyl-CoA C-acetyltransferase 0.0038 0.0074 0.0075
Trichomonas vaginalis fructose-bisphosphate aldolase, putative 0.0118 0.0298 0.1389
Brugia malayi Nuclear hormone receptor family member nhr-3 0.0013 0.0004 0.0002
Trypanosoma brucei importin beta-1 subunit, putative 0.0084 0.0204 0.6066
Trypanosoma cruzi GTP-binding nuclear protein rtb2, putative 0.0055 0.0121 0.3598
Echinococcus multilocularis Aryl hydrocarbon receptor nuclear 0.0017 0.0015 0.0014
Loa Loa (eye worm) Papain cysteine protease/cathepsin propeptide inhibitor-containing protein 0.0019 0.002 0.0021
Schistosoma mansoni dihydrolipoamide dehydrogenase 0.0026 0.004 0.0041
Brugia malayi neuropeptide F receptor 0.0052 0.0114 0.013
Echinococcus granulosus COUP TF:Svp nuclear hormone receptor 0.0013 0.0004 0.0002
Brugia malayi Helix-loop-helix DNA-binding domain containing protein 0.0039 0.0076 0.0086
Schistosoma mansoni biogenic amine receptor 0.0052 0.0114 0.0117
Echinococcus multilocularis g protein linked acetylcholine receptor gar 2a 0.0052 0.0114 0.0113
Entamoeba histolytica fructose-1,6-bisphosphate aldolase, putative 0.0118 0.0298 0.7106
Loa Loa (eye worm) receptor family ligand binding region containing protein 0.0075 0.0178 0.0205
Toxoplasma gondii GTP-binding nuclear protein ran/tc4 0.0055 0.0121 0.3486
Echinococcus granulosus histone acetyltransferase KAT2B 0.0078 0.0186 0.0192
Echinococcus multilocularis cysteine protease 0.0019 0.002 0.0019
Echinococcus granulosus rhodopsin orphan GPCR 0.0052 0.0114 0.0117
Mycobacterium tuberculosis Probable lipase LipD 0.0131 0.0335 0.1445
Brugia malayi G protein-coupled receptor 0.0052 0.0114 0.013
Schistosoma mansoni Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) 0.0016 0.0013 0.0012
Echinococcus multilocularis bromodomain adjacent to zinc finger domain 0.01 0.0248 0.0247
Trypanosoma brucei unspecified product 0.0022 0.0029 0.0828
Brugia malayi Metabotropic glutamate receptor precursor. 0.0286 0.0766 0.0887
Onchocerca volvulus 0.0052 0.0114 0.0523
Brugia malayi Nuclear hormone receptor family member nhr-40 0.0013 0.0004 0.0002
Schistosoma mansoni hypothetical protein 0.0241 0.064 0.0665
Loa Loa (eye worm) hypothetical protein 0.0012 0.0003 0.0001
Echinococcus granulosus FTZ F1 nuclear receptor protein 0.0013 0.0004 0.0002
Leishmania major dihydrolipoamide dehydrogenase, putative 0.0026 0.004 0.1171
Echinococcus multilocularis transcription factor Dp 1 0.0028 0.0047 0.0046
Schistosoma mansoni biogenic amine receptor 0.0052 0.0114 0.0117
Brugia malayi MH1 domain containing protein 0.0054 0.0119 0.0136
Mycobacterium ulcerans polyketide synthase 0.0051 0.0111 0.3289
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0071 0.0167 0.4958
Loa Loa (eye worm) hypothetical protein 0.0052 0.0114 0.013
Echinococcus multilocularis thioredoxin glutathione reductase 0.0075 0.0178 0.0177
Schistosoma mansoni tyrosine kinase 0.0032 0.0058 0.0058
Mycobacterium ulcerans bacterioferritin BfrA 0.0015 0.0009 0.0216
Echinococcus granulosus diuretic hormone 44 receptor GPRdih2 0.0306 0.0821 0.0853
Loa Loa (eye worm) hypothetical protein 0.0026 0.004 0.0045
Trypanosoma cruzi hypothetical protein, conserved 0.0131 0.0335 1
Mycobacterium tuberculosis Probable polyketide synthase Pks7 0.0051 0.0111 0.0478
Schistosoma mansoni hypothetical protein 0.0286 0.0766 0.0796
Leishmania major hypothetical protein, conserved 0.0025 0.0038 0.1089
Brugia malayi Ligand-binding domain of nuclear hormone receptor family protein 0.0013 0.0004 0.0002
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0019 0.002 0.0081
Onchocerca volvulus Alhambra homolog 0.0031 0.0053 0.0237
Trichomonas vaginalis chromodomain-helicase-DNA-binding protein, putative 0.0013 0.0006 0.0012
Mycobacterium ulcerans flavoprotein disulfide reductase 0.0026 0.004 0.1155
Mycobacterium ulcerans DNA polymerase IV 0.0022 0.0029 0.0811
Trypanosoma cruzi DNA polymerase kappa, putative 0.0022 0.0029 0.0828
Giardia lamblia DINP protein human, muc B family 0.0022 0.0029 0.0645
Schistosoma mansoni neuropeptide F-like receptor 0.0052 0.0114 0.0117
Leishmania major cathepsin L-like protease 0.0071 0.0167 0.4958
Echinococcus granulosus acetylcholinesterase 0.0153 0.0396 0.041
Echinococcus multilocularis alpha 1A adrenergic receptor 0.0052 0.0114 0.0113
Echinococcus granulosus sex peptide receptor 0.0052 0.0114 0.0117
Schistosoma mansoni thyrotropin-releasing hormone receptor 0.0052 0.0114 0.0117
Plasmodium falciparum thioredoxin reductase 0.0026 0.004 0.193
Schistosoma mansoni ran 0.0055 0.0121 0.0125
Brugia malayi Receptor family ligand binding region containing protein 0.0075 0.0178 0.0205
Schistosoma mansoni family S9 non-peptidase homologue (S09 family) 0.0026 0.004 0.0041
Trypanosoma cruzi dihydrolipoamide dehydrogenase, putative 0.0026 0.004 0.1171
Schistosoma mansoni opsin-like receptor 0.0052 0.0114 0.0117
Echinococcus multilocularis tyrosine protein kinase Abl 0.0062 0.0142 0.014
Schistosoma mansoni nuclear receptor 2DBD-gamma 0.0013 0.0004 0.0002
Trypanosoma brucei trypanothione reductase 0.0075 0.0177 0.526
Mycobacterium ulcerans Type I modular polyketide synthase 0.0048 0.0103 0.3037
Loa Loa (eye worm) hypothetical protein 0.0013 0.0004 0.0002
Trypanosoma cruzi cysteine peptidase, putative 0.0071 0.0167 0.4958
Leishmania major hypothetical protein, conserved 0.0065 0.015 0.446
Giardia lamblia Fructose-bisphosphate aldolase 0.0118 0.0298 0.9227
Trypanosoma cruzi flap endonuclease-1 (FEN-1), putative 0.0018 0.0019 0.0525
Echinococcus granulosus nmda type glutamate receptor 0.0029 0.005 0.0051
Brugia malayi MH2 domain containing protein 0.1436 0.3978 0.4618
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0052 0.0114 0.0117
Echinococcus granulosus zinc finger protein 0.0035 0.0066 0.0067
Brugia malayi GnHR receptor homolog 0.0052 0.0114 0.013
Schistosoma mansoni cathepsin F (C01 family) 0.0019 0.002 0.002
Loa Loa (eye worm) hypothetical protein 0.01 0.0248 0.0286
Echinococcus granulosus 3 oxoacyl acyl carrier protein synthase 0.0012 0.0002 0.0001
Echinococcus multilocularis neuropeptide Y receptor 0.0052 0.0114 0.0113
Trypanosoma cruzi STE group serine/threonine-protein kinase, putative 0.0026 0.004 0.116
Trichomonas vaginalis glutathione reductase, putative 0.0026 0.004 0.0176
Loa Loa (eye worm) hypothetical protein 0.0052 0.0114 0.013
Mycobacterium leprae PHENOLPTHIOCEROL SYNTHESIS TYPE-I POLYKETIDE SYNTHASE PPSC 0.0051 0.0111 0.2096
Trypanosoma cruzi cysteine peptidase, putative 0.0019 0.002 0.0566
Trypanosoma cruzi trypanothione reductase, putative 0.0026 0.004 0.1171
Brugia malayi Dopamine receptor protein 1 0.0052 0.0114 0.013
Echinococcus multilocularis lysine specific demethylase 6a 0.0016 0.0013 0.0012
Entamoeba histolytica serine/threonine protein kinase, putative 0.0127 0.0322 0.7683
Loa Loa (eye worm) CMGC/DYRK/DYRK1 protein kinase 0.011 0.0274 0.0316
Loa Loa (eye worm) transcription factor SMAD2 0.1436 0.3978 0.4618
Schistosoma mansoni ferritin 0.0015 0.0009 0.0008
Mycobacterium tuberculosis Probable polyketide synthase Pks9 0.0027 0.0045 0.0189
Echinococcus multilocularis COUP TF:Svp nuclear hormone receptor 0.0013 0.0004 0.0002
Brugia malayi jmjC domain containing protein 0.0016 0.0013 0.0013
Trichomonas vaginalis bromodomain-containing protein, putative 0.0027 0.0045 0.0197
Mycobacterium leprae Probable multifunctional mycocerosic acid synthase membrane associated enzyme Mas 0.0051 0.0111 0.2096
Leishmania major hypothetical protein, conserved 0.0016 0.0013 0.0338
Loa Loa (eye worm) hypothetical protein 0.0016 0.0014 0.0014
Leishmania major serine/threonine-protein kinase, putative,protein kinase, putative 0.011 0.0274 0.818
Echinococcus granulosus g protein coupled receptor 0.0052 0.0114 0.0117
Trypanosoma brucei beta-ketoacyl-ACP synthase 0.0012 0.0002 0.0018
Trichomonas vaginalis fructose-bisphosphate aldolase, putative 0.0118 0.0298 0.1389
Entamoeba histolytica cysteine proteinase, putative 0.0019 0.002 0.0484
Trypanosoma brucei hypothetical protein, conserved 0.0131 0.0335 1
Brugia malayi Carboxylesterase family protein 0.0153 0.0396 0.0457
Loa Loa (eye worm) hypothetical protein 0.0038 0.0075 0.0085
Brugia malayi Bromodomain containing protein 0.0064 0.0148 0.0169
Schistosoma mansoni hypothetical protein 0.052 0.142 0.1476
Echinococcus multilocularis 7TM GPCR, rhodopsin 0.0052 0.0114 0.0113
Echinococcus multilocularis cadherin EGF LAG seven pass G type receptor 0.0241 0.064 0.0639
Schistosoma mansoni neuropeptide receptor 0.0052 0.0114 0.0117
Echinococcus granulosus dihydrolipoamide dehydrogenase 0.0026 0.004 0.0041
Mycobacterium ulcerans fusion of enoyl-CoA hydratase, EchA21 and lipase, LipE 0.0131 0.0335 1
Plasmodium falciparum dihydrolipoyl dehydrogenase, apicoplast 0.0026 0.004 0.193
Schistosoma mansoni hypothetical protein 0.0029 0.005 0.005
Schistosoma mansoni neuropeptide receptor 0.0052 0.0114 0.0117
Mycobacterium tuberculosis Probable DNA polymerase III (alpha chain) DnaE2 (DNA nucleotidyltransferase) 0.0101 0.0251 0.1082
Trypanosoma brucei DNA polymerase kappa, putative 0.0022 0.0029 0.0828
Toxoplasma gondii NADPH-glutathione reductase 0.0026 0.004 0.1134
Brugia malayi hypothetical protein 0.0039 0.0076 0.0086
Trypanosoma cruzi CMGC/DYRK protein kinase, putative 0.011 0.0274 0.818
Trypanosoma cruzi PAS-domain containing phosphoglycerate kinase, putative 0.0016 0.0014 0.0383
Loa Loa (eye worm) hypothetical protein 0.0029 0.005 0.0056
Trichomonas vaginalis ferritin, putative 0.0015 0.0009 0.0029
Mycobacterium leprae PHENOLPTHIOCEROL SYNTHESIS TYPE-I POLYKETIDE SYNTHASE PPSE 0.0032 0.0057 0.0987
Loa Loa (eye worm) hypothetical protein 0.0014 0.0008 0.0007
Loa Loa (eye worm) hypothetical protein 0.0062 0.0143 0.0163
Echinococcus granulosus glutamate receptor 2 0.0035 0.0065 0.0067
Schistosoma mansoni retinoic acid receptor RXR 0.0013 0.0004 0.0002
Loa Loa (eye worm) hypothetical protein 0.0029 0.005 0.0056
Echinococcus multilocularis histone lysine N methyltransferase SETMAR 0.0098 0.0241 0.024
Schistosoma mansoni kinesin eg-5 0.0016 0.0011 0.001
Schistosoma mansoni amine GPCR 0.0052 0.0114 0.0117
Trichomonas vaginalis Clan CA, family C1, papain-like cysteine peptidase 0.0019 0.002 0.0081
Echinococcus granulosus smad 0.0098 0.0241 0.025
Echinococcus multilocularis glutamate receptor 2 0.0035 0.0065 0.0064
Echinococcus granulosus survival motor neuron protein 1 0.0137 0.0352 0.0365
Loa Loa (eye worm) hypothetical protein 0.0052 0.0114 0.013
Schistosoma mansoni neuropeptide receptor 0.0052 0.0114 0.0117
Echinococcus multilocularis GPCR, family 2 0.0241 0.064 0.0639
Loa Loa (eye worm) acetylcholinesterase 1 0.0153 0.0396 0.0457
Brugia malayi oxidoreductase, zinc-binding dehydrogenase family protein 0.0092 0.0224 0.0258
Echinococcus multilocularis smad 0.0098 0.0241 0.024
Echinococcus granulosus importin 5 0.0016 0.0013 0.0012
Trichomonas vaginalis penicillin-binding protein, putative 0.0131 0.0335 0.1563
Echinococcus multilocularis tumor protein p63 0.0924 0.2547 0.2546
Schistosoma mansoni neuropeptide f receptor 76f 0.0052 0.0114 0.0117
Giardia lamblia GTP-binding nuclear protein RAN/TC4 0.0055 0.0121 0.3593
Brugia malayi beta-lactamase family protein 0.0131 0.0335 0.0386
Echinococcus multilocularis neuropeptide receptor A26 0.0052 0.0114 0.0113
Echinococcus granulosus thioredoxin glutathione reductase 0.0075 0.0178 0.0184
Brugia malayi metabotropic glutamate receptor type 2 0.0141 0.0361 0.0417
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0019 0.002 0.0081
Echinococcus granulosus jumonji domain containing protein 0.0043 0.0087 0.0089
Schistosoma mansoni cpg binding protein 0.0024 0.0036 0.0036
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0052 0.0114 0.0117
Onchocerca volvulus Bile acid receptor homolog 0.0013 0.0004 0.0003
Loa Loa (eye worm) hypothetical protein 0.0383 0.1037 0.1202
Echinococcus granulosus metabotropic glutamate receptor 2 0.024 0.0638 0.0662
Echinococcus multilocularis snurportin 1 0.09 0.2482 0.2481
Schistosoma mansoni tar DNA-binding protein 0.0123 0.0312 0.0323
Echinococcus granulosus histone acetyltransferase KAT2B 0.0027 0.0045 0.0045
Onchocerca volvulus 0.0026 0.004 0.0176
Trichomonas vaginalis conserved hypothetical protein 0.0021 0.0028 0.0118
Trichomonas vaginalis fructose-bisphosphate aldolase, putative 0.0118 0.0298 0.1389
Brugia malayi Flap endonuclease-1 0.0018 0.0019 0.002
Mycobacterium tuberculosis Dihydrolipoamide dehydrogenase LpdC (lipoamide reductase (NADH)) (lipoyl dehydrogenase) (dihydrolipoyl dehydrogenase) (diaphoras 0.0189 0.0497 0.2148
Schistosoma mansoni methyltransferase-related 0.0015 0.0009 0.0008
Echinococcus multilocularis GPCR, family 3, C terminal 0.0046 0.0096 0.0095
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0071 0.0167 0.4958
Loa Loa (eye worm) hypothetical protein 0.0019 0.002 0.0021
Brugia malayi SET domain containing protein 0.0013 0.0004 0.0002
Brugia malayi Corticotropin releasing factor receptor 2 precursor, putative 0.0825 0.2273 0.2637
Onchocerca volvulus 0.0052 0.0114 0.0523
Schistosoma mansoni mixed-lineage leukemia protein mll 0.0019 0.002 0.0019
Brugia malayi ORL1-like opioid receptor 0.0052 0.0114 0.013
Mycobacterium tuberculosis Phenyloxazoline synthase MbtB (phenyloxazoline synthetase) 0.0045 0.0094 0.0403
Mycobacterium ulcerans polyketide synthase Pks13 0.0072 0.017 0.5043
Loa Loa (eye worm) hypothetical protein 0.0052 0.0114 0.013
Schistosoma mansoni cathepsin F (C01 family) 0.0019 0.002 0.002
Loa Loa (eye worm) unidentified vitellogenin-linked transcript protein 6 0.0052 0.0114 0.013
Brugia malayi Iron-sulfur cluster assembly accessory protein 0.0028 0.0046 0.0052
Plasmodium vivax hypothetical protein, conserved 0.0031 0.0053 0.1545
Trypanosoma brucei DNA polymerase kappa, putative 0.0022 0.0029 0.0828
Loa Loa (eye worm) hypothetical protein 0.0137 0.0352 0.0406
Loa Loa (eye worm) carboxylesterase 0.0026 0.004 0.0045
Echinococcus granulosus nmda type glutamate receptor 0.0019 0.0022 0.0022
Echinococcus granulosus tm gpcr rhodopsin 0.0052 0.0114 0.0117
Brugia malayi Cathepsin L-like precursor 0.0019 0.002 0.0021
Brugia malayi kap beta 3 protein 0.0016 0.0013 0.0012
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0019 0.002 0.0081
Echinococcus granulosus G protein coupled 5 hydroxytryptamine receptor 0.0052 0.0114 0.0117
Echinococcus granulosus alpha 1A adrenergic receptor 0.0052 0.0114 0.0117
Brugia malayi hypothetical protein 0.0052 0.0114 0.013
Echinococcus multilocularis nuclear receptor 2DBD gamma 0.0013 0.0004 0.0002
Leishmania major dihydrolipoamide dehydrogenase, putative 0.0026 0.004 0.1171
Echinococcus granulosus peptide allatostatin:somatostatin 0.0052 0.0114 0.0117
Schistosoma mansoni ferritin 0.0015 0.0009 0.0008
Brugia malayi RNA recognition motif domain containing protein 0.0123 0.0312 0.036
Brugia malayi MH1 domain containing protein 0.0098 0.0241 0.0278
Schistosoma mansoni smad 0.0044 0.009 0.0093
Brugia malayi Calcitonin receptor-like protein seb-1 0.076 0.2091 0.2427
Mycobacterium ulcerans lipase LipD 0.0131 0.0335 1
Loa Loa (eye worm) hypothetical protein 0.0052 0.0114 0.013
Brugia malayi Melatonin receptor type 1A 0.0052 0.0114 0.013
Brugia malayi Tyrosine-protein kinase abl-1 0.0062 0.0142 0.0162
Plasmodium falciparum transportin 0.0016 0.0013 0.0558
Schistosoma mansoni family S12 unassigned peptidase (S12 family) 0.0131 0.0335 0.0347
Schistosoma mansoni biogenic amine (5HT) receptor 0.0052 0.0114 0.0117
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0052 0.0114 0.0117
Brugia malayi Cathepsin L-like precursor 0.0019 0.002 0.0021
Schistosoma mansoni tar DNA-binding protein 0.0123 0.0312 0.0323
Echinococcus granulosus cathepsin l1 0.0012 0.0003 0.0002
Entamoeba histolytica cysteine protease, putative 0.0019 0.002 0.0484
Brugia malayi Nuclear hormone receptor family member nhr-19 0.0013 0.0004 0.0002
Chlamydia trachomatis DNA polymerase III subunit alpha 0.0101 0.025 1
Brugia malayi jmjC domain containing protein 0.0124 0.0314 0.0362
Brugia malayi Smad1 0.0098 0.0241 0.0278
Mycobacterium ulcerans polyketide synthase Pks9 0.0032 0.0057 0.1664
Plasmodium vivax GTP-binding nuclear protein RAN/TC4, putative 0.0055 0.0121 0.3586
Trypanosoma cruzi CMGC/DYRK protein kinase, putative 0.011 0.0274 0.818
Loa Loa (eye worm) tyrosyl-DNA phosphodiesterase 0.0049 0.0105 0.0119
Trypanosoma brucei GTP-binding nuclear protein rtb2, putative 0.0055 0.0121 0.3598
Trichomonas vaginalis Clan CA, family C1, cathepsin L or K-like cysteine peptidase 0.0019 0.002 0.0081
Brugia malayi Tyrosyl-DNA phosphodiesterase family protein 0.0049 0.0105 0.0119
Echinococcus multilocularis cysteine protease 0.0019 0.002 0.0019
Echinococcus granulosus g protein coupled receptor 0.0052 0.0114 0.0117
Brugia malayi Cathepsin L-like precursor 0.0012 0.0003 0.0001
Entamoeba histolytica hypothetical protein 0.0162 0.0419 1
Echinococcus multilocularis cpg binding protein 0.0024 0.0036 0.0035
Loa Loa (eye worm) Smad1 0.0098 0.0241 0.0278
Echinococcus granulosus somatostatin receptor 0.0052 0.0114 0.0117
Loa Loa (eye worm) hypothetical protein 0.0038 0.0075 0.0085
Trypanosoma brucei DNA polymerase kappa, putative 0.0022 0.0029 0.0828
Echinococcus multilocularis BC026374 protein (S09 family) 0.0026 0.004 0.0039
Schistosoma mansoni single-minded 0.0016 0.0014 0.0013
Echinococcus multilocularis g protein coupled receptor 0.0052 0.0114 0.0113
Brugia malayi ImpB/MucB/SamB family protein 0.0022 0.0029 0.0031
Loa Loa (eye worm) hypothetical protein 0.0052 0.0114 0.013
Brugia malayi gonadotropin-releasing hormone receptor 2 0.0052 0.0114 0.013
Onchocerca volvulus 0.0019 0.002 0.0081
Loa Loa (eye worm) hypothetical protein 0.0029 0.005 0.0056
Schistosoma mansoni Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) 0.0016 0.0013 0.0012
Loa Loa (eye worm) acyl carrier protein 0.0022 0.003 0.0033
Treponema pallidum fructose-bisphosphate aldolase 0.0118 0.0298 1
Loa Loa (eye worm) pigment dispersing factor receptor c 0.076 0.2091 0.2427
Entamoeba histolytica protein kinase domain containing protein 0.0012 0.0001 0.0034
Mycobacterium tuberculosis Conserved protein 0.0015 0.0009 0.0033
Trypanosoma cruzi beta-ketoacyl synthase family protein, putative 0.0012 0.0002 0.0018
Mycobacterium tuberculosis Probable reductase 0.017 0.0444 0.1918
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0019 0.002 0.0081
Trichomonas vaginalis fructose-bisphosphate aldolase, putative 0.0118 0.0298 0.1389
Toxoplasma gondii type I fatty acid synthase, putative 0.0051 0.0111 0.3199
Onchocerca volvulus Cathepsin L homolog 0.0019 0.002 0.0081
Toxoplasma gondii ABC1 family protein 0.0131 0.0335 0.9689
Echinococcus granulosus rhodopsin orphan GPCR 0.0052 0.0114 0.0117
Echinococcus granulosus Transcription factor JmjC domain containing protein 0.0124 0.0314 0.0325
Schistosoma mansoni gliotactin 0.0026 0.004 0.0041
Schistosoma mansoni histone-lysine n-methyltransferase setb1 0.0126 0.0319 0.033
Echinococcus granulosus rhodopsin orphan GPCR 0.0052 0.0114 0.0117
Loa Loa (eye worm) nucleolar RNA-associated protein alpha 0.09 0.2482 0.288
Echinococcus granulosus terminal deoxycytidyl transferase rev1 0.0022 0.0029 0.0029
Echinococcus granulosus beta LACTamase domain containing family member 0.0131 0.0335 0.0347
Brugia malayi photoreceptor-specific nuclear receptor 0.0013 0.0004 0.0002
Entamoeba histolytica tyrosyl-DNA phosphodiesterase, putative 0.0049 0.0105 0.2501
Brugia malayi hypothetical protein 0.0045 0.0094 0.0107
Chlamydia trachomatis glutamine binding protein 0.0014 0.0007 0.02
Loa Loa (eye worm) nuclear hormone receptor family member nhr-1 0.0013 0.0004 0.0002
Echinococcus multilocularis serotonin receptor 0.0052 0.0114 0.0113
Brugia malayi larval opioid receptor 0.0052 0.0114 0.013
Mycobacterium tuberculosis Probable conserved lipoprotein 0.0131 0.0335 0.1445
Plasmodium falciparum JmjC domain-containing protein, putative 0.0016 0.0013 0.0591
Loa Loa (eye worm) hypothetical protein 0.0052 0.0114 0.013
Schistosoma mansoni biogenic amine (octopamine/dopamine) receptor 0.0272 0.0728 0.0756
Echinococcus multilocularis tar DNA binding protein 0.0123 0.0312 0.0311
Echinococcus multilocularis rhodopsin orphan GPCR 0.0052 0.0114 0.0113
Schistosoma mansoni biogenic amine (5HT) receptor 0.0825 0.2271 0.2363
Schistosoma mansoni neuropeptide receptor 0.0052 0.0114 0.0117
Loa Loa (eye worm) glutamate receptor 0.0286 0.0766 0.0887
Schistosoma mansoni family S12 unassigned peptidase (S12 family) 0.0131 0.0335 0.0347
Trypanosoma brucei DNA polymerase eta, putative 0.0022 0.0029 0.0828
Schistosoma mansoni opsin-like receptor 0.0052 0.0114 0.0117
Loa Loa (eye worm) pre-SET domain-containing protein family protein 0.0679 0.1863 0.2162
Echinococcus granulosus family S9 non peptidase ue S09 family 0.0026 0.004 0.0041
Schistosoma mansoni ferritin light chain 0.0015 0.0009 0.0008
Schistosoma mansoni hypothetical protein 0.0104 0.0258 0.0267
Loa Loa (eye worm) hypothetical protein 0.0272 0.0728 0.0843
Brugia malayi Cathepsin L-like precursor 0.0019 0.002 0.0021
Toxoplasma gondii histone lysine demethylase JMJC1/KDM5D/JARID1D 0.0016 0.0013 0.0348
Mycobacterium ulcerans polyketide synthase MbtD 0.0015 0.001 0.0229
Loa Loa (eye worm) jmjC domain-containing protein 0.0065 0.015 0.0171
Trypanosoma cruzi STE group serine/threonine-protein kinase, putative 0.0026 0.004 0.116
Loa Loa (eye worm) neuropeptide F receptor 0.0052 0.0114 0.013
Echinococcus granulosus geminin 0.3452 0.9607 1
Onchocerca volvulus 0.0032 0.0058 0.0257
Trypanosoma cruzi cysteine peptidase, putative 0.0071 0.0167 0.4958
Brugia malayi Nuclear hormone receptor family member nhr-41 0.0013 0.0004 0.0002
Brugia malayi G-protein-linked acetylcholine receptor protein 2, putative 0.0052 0.0114 0.013
Echinococcus granulosus chromodomain helicase DNA binding protein 4 0.0013 0.0005 0.0004
Echinococcus multilocularis Jumonji, AT rich interactive domain 1B 0.002 0.0025 0.0024
Schistosoma mansoni jumonji domain containing protein 0.0103 0.0256 0.0265
Loa Loa (eye worm) hypothetical protein 0.0022 0.0029 0.0031
Brugia malayi Receptor family ligand binding region containing protein 0.0032 0.0058 0.0064
Echinococcus multilocularis diuretic hormone 44 receptor GPRdih2 0.0306 0.0821 0.082
Mycobacterium leprae Probable lipase LipE 0.0131 0.0335 0.6672
Loa Loa (eye worm) beta-LACTamase domain containing family member 0.0131 0.0335 0.0386
Echinococcus granulosus neuropeptide receptor A26 0.0052 0.0114 0.0117
Mycobacterium tuberculosis POSSIBLE PARA-NITROBENZYL ESTERASE (FRAGMENT) 0.0026 0.004 0.017
Brugia malayi aryl hydrocarbon receptor AHR-1 0.0038 0.0075 0.0085
Mycobacterium tuberculosis Probable nitrite reductase [NAD(P)H] large subunit [FAD flavoprotein] NirB 0.017 0.0444 0.1918
Loa Loa (eye worm) helix-loop-helix DNA-binding domain-containing protein 0.0039 0.0076 0.0086
Echinococcus granulosus histone lysine methyltransferase setb 0.0126 0.0319 0.033
Echinococcus granulosus expressed protein 0.0015 0.0009 0.0008
Brugia malayi hypothetical protein 0.0052 0.0114 0.013
Echinococcus multilocularis carboxylesterase 5A 0.0153 0.0396 0.0394
Loa Loa (eye worm) RNA recognition domain-containing protein domain-containing protein 0.0123 0.0312 0.036
Loa Loa (eye worm) heterochromatin protein 1 0.0054 0.0119 0.0136
Leishmania major DNA polymerase kappa, putative,DNA polymerase IV, putative 0.0022 0.0029 0.0828
Echinococcus multilocularis glutamate receptor, ionotrophic, AMPA 3 0.0035 0.0065 0.0064
Trypanosoma cruzi DNA polymerase kappa, putative 0.0022 0.0029 0.0828
Loa Loa (eye worm) RGC/RGC protein kinase 0.0032 0.0058 0.0064
Loa Loa (eye worm) hypothetical protein 0.0058 0.013 0.0149
Loa Loa (eye worm) TYRA-2 protein 0.0052 0.0114 0.013
Onchocerca volvulus Heterochromatin protein 1 homolog 0.003 0.0053 0.0235
Echinococcus granulosus neuropeptide FF receptor 2 0.0052 0.0114 0.0117
Loa Loa (eye worm) MH2 domain-containing protein 0.0098 0.0241 0.0278
Wolbachia endosymbiont of Brugia malayi dihydrolipoamide dehydrogenase E3 component 0.0026 0.004 0.1552
Mycobacterium tuberculosis Probable membrane NADH dehydrogenase NdhA 0.017 0.0444 0.1918
Echinococcus granulosus GPCR family 3 C terminal 0.0046 0.0096 0.0099
Brugia malayi hypothetical protein 0.0052 0.0114 0.013
Giardia lamblia Kinesin-5 0.0016 0.0011 0.0084
Echinococcus granulosus cadherin EGF LAG seven pass G type receptor 0.0241 0.064 0.0665
Brugia malayi CXXC zinc finger family protein 0.002 0.0024 0.0026
Brugia malayi Nuclear hormone receptor family member nhr-14 0.0013 0.0004 0.0002
Toxoplasma gondii histone lysine acetyltransferase GCN5-B 0.0027 0.0045 0.1264
Echinococcus granulosus acetylcholinesterase 0.0153 0.0396 0.041
Loa Loa (eye worm) MH1 domain-containing protein 0.0098 0.0241 0.0278
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0019 0.002 0.0081
Schistosoma mansoni methyl-cpg binding protein mbd 0.0028 0.0046 0.0046
Schistosoma mansoni ubiquitously transcribed sex (X/Y) chromosome tetratricopeptide repeat protein-related 0.0016 0.0013 0.0012
Schistosoma mansoni tyrosine kinase 0.0032 0.0058 0.0058
Schistosoma mansoni hypothetical protein 0.0241 0.064 0.0665
Brugia malayi jmjC domain containing protein 0.0016 0.0013 0.0013
Mycobacterium ulcerans DNA polymerase IV 0.0022 0.0029 0.0811
Trichomonas vaginalis esterase, putative 0.0131 0.0335 0.1563
Echinococcus multilocularis allatostatin A receptor 0.0052 0.0114 0.0113
Schistosoma mansoni smad1 5 8 and 0.0098 0.0241 0.025
Echinococcus multilocularis Smad4 0.0098 0.0241 0.024
Trypanosoma cruzi JmjC domain, hydroxylase, putative 0.0016 0.0013 0.0359
Plasmodium falciparum GTP-binding nuclear protein RAN/TC4 0.0055 0.0121 0.5931
Echinococcus multilocularis 3 oxoacyl (acyl carrier protein) synthase 0.0012 0.0002 0.0001
Trichomonas vaginalis adenylate and guanylate cyclases, putative 0.0016 0.0014 0.0052
Mycobacterium leprae Polyketide synthase Pks13 0.0072 0.017 0.3292
Echinococcus granulosus tyrosyl DNA phosphodiesterase 1 0.0049 0.0105 0.0108
Echinococcus multilocularis nuclear receptor 2DBD gamma 0.0013 0.0004 0.0002
Echinococcus multilocularis GTP binding nuclear protein Ran 0.0055 0.0121 0.012
Loa Loa (eye worm) metabotropic GABA-B receptor subtype 2 0.0075 0.0178 0.0205
Mycobacterium tuberculosis Probable esterase LipL 0.0131 0.0335 0.1445
Echinococcus granulosus cathepsin l1 0.0019 0.002 0.002
Brugia malayi AMP-binding enzyme family protein 0.0015 0.001 0.0009
Toxoplasma gondii cathepsin CPL 0.0019 0.002 0.0548
Brugia malayi Serotonin receptor 0.0052 0.0114 0.013
Schistosoma mansoni phd/f-box containing protein 0.0016 0.0013 0.0012
Mycobacterium ulcerans hypothetical protein 0.0019 0.0021 0.0582
Schistosoma mansoni biogenic amine receptor 0.0052 0.0114 0.0117
Leishmania major cathepsin L-like protease 0.0019 0.002 0.0566
Mycobacterium ulcerans beta-lactamase 0.0131 0.0335 1
Loa Loa (eye worm) hypothetical protein 0.0026 0.004 0.0045
Plasmodium falciparum kinesin-5 0.0016 0.0011 0.0496
Loa Loa (eye worm) MH2 domain-containing protein 0.1436 0.3978 0.4618
Schistosoma mansoni histamine h1 receptor 0.0052 0.0114 0.0117
Onchocerca volvulus 0.0131 0.0335 0.1563
Leishmania major trypanothione reductase 0.0075 0.0177 0.526
Brugia malayi glutathione reductase 0.0075 0.0177 0.0203
Mycobacterium tuberculosis Polyketide synthase Pks2 0.0047 0.0099 0.0424
Onchocerca volvulus 0.0052 0.0114 0.0523
Echinococcus multilocularis chromobox protein 1 0.0054 0.0119 0.0118
Trypanosoma brucei DNA polymerase kappa, putative 0.0022 0.0029 0.0828
Plasmodium falciparum flap endonuclease 1 0.0018 0.0019 0.0866
Schistosoma mansoni kinase 0.0069 0.016 0.0165
Brugia malayi hypothetical protein 0.0026 0.004 0.0045
Trypanosoma cruzi DNA polymerase kappa, putative 0.0022 0.0029 0.0828
Trypanosoma cruzi polo-like protein kinase, putative 0.0127 0.0322 0.9618
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0052 0.0114 0.0117
Trypanosoma cruzi extracellular receptor, putative 0.0029 0.005 0.1463
Loa Loa (eye worm) cysteine protease 0.0019 0.002 0.0021
Plasmodium vivax glutathione reductase, putative 0.0075 0.0177 0.5252
Loa Loa (eye worm) ctsf protein 0.0019 0.002 0.0021
Echinococcus multilocularis MAP kinase activated protein kinase 2 0.3096 0.8612 0.8612
Echinococcus granulosus 5'partial|histone lysine N methyltransferase SETDB2 0.0094 0.023 0.0238
Onchocerca volvulus 0.0135 0.0346 0.1614
Leishmania major cathepsin L-like protease 0.0071 0.0167 0.4958
Schistosoma mansoni hypothetical protein 0.0028 0.0046 0.0047
Trypanosoma cruzi polo-like protein kinase, putative 0.0127 0.0322 0.9618
Echinococcus granulosus nuclear receptor 2DBD gamma 0.0013 0.0004 0.0002
Entamoeba histolytica hypothetical protein 0.0068 0.0159 0.3796
Brugia malayi GTP-binding nuclear protein RAN/TC4 0.0055 0.0121 0.0139
Schistosoma mansoni hypothetical protein 0.0031 0.0053 0.0054
Loa Loa (eye worm) hypothetical protein 0.0052 0.0114 0.013
Brugia malayi G-protein coupled receptor 0.0052 0.0114 0.013
Echinococcus multilocularis rhodopsin orphan GPCR 0.0052 0.0114 0.0113
Schistosoma mansoni hypothetical protein 0.09 0.2482 0.2582
Brugia malayi RNA binding protein 0.0123 0.0312 0.036
Mycobacterium tuberculosis Probable esterase/lipase LipP 0.0131 0.0335 0.1445
Schistosoma mansoni neuropeptide F-like receptor 0.0052 0.0114 0.0117
Echinococcus granulosus Aryl hydrocarbon receptor nuclear 0.0017 0.0015 0.0014
Onchocerca volvulus 0.0052 0.0114 0.0523
Schistosoma mansoni importin-beta 2 0.0016 0.0013 0.0012
Loa Loa (eye worm) kinesin-like protein KLP2 0.0016 0.0011 0.0011
Schistosoma mansoni coup transcription factor 0.0013 0.0004 0.0002
Loa Loa (eye worm) hypothetical protein 0.0026 0.004 0.0045
Echinococcus multilocularis nmda type glutamate receptor 0.0029 0.005 0.0049
Loa Loa (eye worm) carboxylesterase 0.0153 0.0396 0.0457
Trichomonas vaginalis conserved hypothetical protein 0.0016 0.0014 0.0052
Echinococcus multilocularis metabotropic glutamate receptor 5 0.0351 0.0948 0.0947
Loa Loa (eye worm) steroid hormone receptor 0.0013 0.0004 0.0002
Echinococcus granulosus tar DNA binding protein 0.0123 0.0312 0.0323
Echinococcus multilocularis G protein coupled 5 hydroxytryptamine receptor 0.0052 0.0114 0.0113
Echinococcus multilocularis tyrosine protein kinase ABL1 0.0149 0.0385 0.0384
Schistosoma mansoni family S9 non-peptidase homologue (S09 family) 0.0026 0.004 0.0041
Onchocerca volvulus Cathepsin F homolog 0.0019 0.002 0.0081
Trypanosoma cruzi dihydrolipoamide dehydrogenase, putative 0.0026 0.004 0.1171
Toxoplasma gondii HEAT repeat-containing protein 0.0084 0.0204 0.5877
Echinococcus granulosus atrial natriuretic peptide receptor 0.0029 0.005 0.0051
Loa Loa (eye worm) importin-beta domain-containing protein 0.0016 0.0013 0.0012
Mycobacterium tuberculosis Probable fructose-bisphosphate aldolase Fba 0.0058 0.0129 0.0555
Schistosoma mansoni mixed-lineage leukemia protein mll 0.0046 0.0097 0.0099
Loa Loa (eye worm) hypothetical protein 0.0038 0.0075 0.0085
Plasmodium vivax SET domain protein, putative 0.0098 0.0241 0.7183
Brugia malayi steroid hormone receptor 0.0013 0.0004 0.0002
Echinococcus multilocularis terminal deoxycytidyl transferase rev1 0.0022 0.0029 0.0028
Brugia malayi CHD4 protein 0.0013 0.0005 0.0003
Plasmodium vivax histone acetyltransferase GCN5, putative 0.0027 0.0045 0.1289
Treponema pallidum DNA polymerase III subunit alpha 0.0101 0.025 0.834
Mycobacterium tuberculosis Probable NADH dehydrogenase Ndh 0.017 0.0444 0.1918
Brugia malayi Ligand-binding domain of nuclear hormone receptor family protein 0.0013 0.0004 0.0002
Mycobacterium tuberculosis Phenolpthiocerol synthesis type-I polyketide synthase PpsC 0.0048 0.0103 0.0442
Echinococcus multilocularis flap endonuclease 1 0.0018 0.0019 0.0018
Onchocerca volvulus Steroid hormone receptor family member cnr14 homolog 0.0013 0.0004 0.0003
Loa Loa (eye worm) papain family cysteine protease containing protein 0.0019 0.002 0.0021
Entamoeba histolytica acetyltransferase, GNAT family 0.0022 0.0029 0.0684
Leishmania major hypothetical protein, conserved 0.0016 0.0013 0.0359
Onchocerca volvulus 0.0052 0.0114 0.0523
Schistosoma mansoni serine/threonine protein kinase 0.011 0.0274 0.0284
Schistosoma mansoni glutamate receptor NMDA 0.0035 0.0065 0.0067
Echinococcus multilocularis neuropeptides capa receptor 0.0052 0.0114 0.0113
Trichomonas vaginalis conserved hypothetical protein 0.0021 0.0028 0.0118
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0052 0.0114 0.0117
Schistosoma mansoni neuroligin 3 (S09 family) 0.0026 0.004 0.0041
Mycobacterium ulcerans fructose-bisphosphate aldolase 0.0058 0.0129 0.3822
Brugia malayi Carboxylesterase family protein 0.0153 0.0396 0.0457
Loa Loa (eye worm) RGC/RGC protein kinase 0.0032 0.0058 0.0064
Echinococcus multilocularis expressed protein 0.0015 0.0009 0.0008
Onchocerca volvulus 0.0052 0.0114 0.0523
Loa Loa (eye worm) hypothetical protein 0.0029 0.005 0.0056
Chlamydia trachomatis dihydrolipoyl dehydrogenase 0.0026 0.004 0.1552
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0019 0.002 0.0081
Mycobacterium tuberculosis Polyketide synthase Pks13 0.0072 0.017 0.0731
Loa Loa (eye worm) hypothetical protein 0.052 0.142 0.1646
Loa Loa (eye worm) GTP-binding nuclear protein RAN/TC4 0.0055 0.0121 0.0139
Echinococcus granulosus ferritin 0.0015 0.0009 0.0008
Echinococcus granulosus pyroglutamylated rfamide peptide receptor 0.0052 0.0114 0.0117
Schistosoma mansoni rab geranylgeranyl transferase alpha subunit 0.0022 0.0029 0.0029
Loa Loa (eye worm) TAR-binding protein 0.0123 0.0312 0.036
Brugia malayi Tyrosine-protein kinase abl-1 0.0089 0.0218 0.025
Schistosoma mansoni family S9 non-peptidase homologue (S09 family) 0.0153 0.0396 0.041
Schistosoma mansoni peptide (allatostatin)-like receptor 0.0052 0.0114 0.0117
Brugia malayi hypothetical protein 0.0052 0.0114 0.013
Mycobacterium ulcerans fatty acid synthase Fas 0.0015 0.0011 0.0256
Echinococcus granulosus glutamate receptor 2 0.0029 0.005 0.0051
Leishmania major GTP-binding protein, putative 0.0055 0.0121 0.3598
Onchocerca volvulus 0.0024 0.0035 0.0149
Echinococcus multilocularis rhodopsin orphan GPCR 0.0052 0.0114 0.0113
Schistosoma mansoni hypothetical protein 0.0034 0.0062 0.0063
Loa Loa (eye worm) hypothetical protein 0.0068 0.0159 0.0182
Echinococcus multilocularis peptide (allatostatin:somatostatin) 0.0052 0.0114 0.0113
Entamoeba histolytica Ran family GTPase 0.0055 0.0121 0.2896
Echinococcus multilocularis rhodopsin orphan GPCR 0.0052 0.0114 0.0113
Onchocerca volvulus 0.0026 0.004 0.0176
Loa Loa (eye worm) hypothetical protein 0.0272 0.0728 0.0843
Trichomonas vaginalis hypothetical protein 0.0016 0.0013 0.0045
Echinococcus granulosus tm gpcr rhodopsin 0.0052 0.0114 0.0117
Mycobacterium tuberculosis Probable polyketide synthase Pks8 0.004 0.0079 0.0335
Echinococcus multilocularis Glutamate receptor, ionotropic kainate 3 0.0019 0.0022 0.0021
Brugia malayi PHD-finger family protein 0.0044 0.009 0.0102
Echinococcus granulosus GTP binding nuclear protein Ran 0.0055 0.0121 0.0125
Loa Loa (eye worm) hypothetical protein 0.0052 0.0114 0.013
Mycobacterium tuberculosis Bacterioferritin BfrB 0.0015 0.0009 0.0035
Toxoplasma gondii pyruvate dehydrogenase complex subunit PDH-E3II 0.0026 0.004 0.1134
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0071 0.0167 0.4958
Leishmania major tyrosyl-DNA phosphodiesterase 1 0.0049 0.0105 0.3101
Plasmodium vivax JmjC domain containing protein 0.0016 0.0013 0.0341
Mycobacterium tuberculosis Conserved hypothetical protein 0.0019 0.0021 0.0088
Echinococcus granulosus Ataxin 2 N terminaldomain containing protein 0.0029 0.005 0.005
Loa Loa (eye worm) jmjC domain-containing protein 0.0016 0.0013 0.0013
Loa Loa (eye worm) G-protein coupled receptor 0.0052 0.0114 0.013
Echinococcus granulosus nuclear receptor 2DBD gamma 0.0013 0.0004 0.0002
Brugia malayi hypothetical protein 0.0042 0.0086 0.0097
Echinococcus granulosus jumonji domain containing 1A 0.0016 0.0013 0.0012
Plasmodium vivax thioredoxin reductase, putative 0.0075 0.0177 0.5252
Trichomonas vaginalis Clan CA, family C1, papain-like cysteine peptidase 0.0019 0.002 0.0081
Entamoeba histolytica fructose-1,6-bisphosphate aldolase, putative 0.0118 0.0298 0.7106
Brugia malayi F/Y-rich N-terminus family protein 0.0023 0.0032 0.0035
Trichomonas vaginalis CAMK family protein kinase 0.0127 0.0322 0.1503
Leishmania major beta-ketoacyl synthase family protein, putative,3-oxoacyl-acyl carrier protein synthase ii, putative 0.0012 0.0002 0.0018
Schistosoma mansoni cathepsin F (C01 family) 0.0012 0.0003 0.0002
Loa Loa (eye worm) hypothetical protein 0.0013 0.0004 0.0002
Brugia malayi RNA, U transporter 1 0.024 0.0638 0.0738
Echinococcus multilocularis aryl hydrocarbon receptor 0.0055 0.0122 0.0121
Toxoplasma gondii beta-ketoacyl synthase, N-terminal domain-containing protein 0.0031 0.0056 0.1578
Trypanosoma cruzi PAB1-binding protein , putative 0.0065 0.015 0.446
Trypanosoma cruzi dihydrolipoyl dehydrogenase, putative 0.0026 0.004 0.1171
Trypanosoma brucei CMGC/DYRK protein kinase, putative 0.011 0.0274 0.818
Trichomonas vaginalis chromodomain helicase DNA binding protein, putative 0.0013 0.0006 0.0012
Trypanosoma brucei Importin-beta N-terminal domain/HEAT-like repeat, putative 0.0016 0.0013 0.0338
Mycobacterium tuberculosis Probable polyketide synthase Pks5 0.0047 0.0099 0.0424
Loa Loa (eye worm) hypothetical protein 0.0016 0.0013 0.0013
Loa Loa (eye worm) AMP-binding enzyme family protein 0.0045 0.0094 0.0107
Brugia malayi Carboxylesterase family protein 0.0026 0.004 0.0045
Mycobacterium tuberculosis Probable DNA polymerase III (alpha chain) DnaE1 (DNA nucleotidyltransferase) 0.0101 0.0251 0.1082
Trichomonas vaginalis Clan CA, family C1, cathepsin L or K-like cysteine peptidase 0.0019 0.002 0.0081
Brugia malayi nuclear hormone receptor 0.0013 0.0004 0.0002
Trypanosoma brucei DNA polymerase kappa, putative 0.0022 0.0029 0.0828
Loa Loa (eye worm) neuropeptide F receptor 0.0052 0.0114 0.013
Brugia malayi Tachykinin-like peptides receptor 99D 0.0052 0.0114 0.013
Schistosoma mansoni thyroid hormone receptor 0.0013 0.0004 0.0002
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0071 0.0167 0.4958
Toxoplasma gondii HEAT repeat-containing protein 0.0016 0.0013 0.0328
Loa Loa (eye worm) glutamate receptor 0.0111 0.0279 0.0322
Onchocerca volvulus Fatty acid synthase homolog 0.0087 0.0211 0.0982
Schistosoma mansoni chromodomain helicase DNA binding protein 0.0013 0.0005 0.0004
Echinococcus granulosus mothers against decapentaplegic 5 0.0098 0.0241 0.025
Echinococcus multilocularis cathepsin l cysteine peptidase 0.0019 0.002 0.0019
Treponema pallidum bacterioferrin (TpF1) 0.0015 0.0009 0.0077
Mycobacterium ulcerans phenolpthiocerol synthesis type-I polyketide synthase PpsA 0.0039 0.0077 0.2245
Plasmodium falciparum cysteine proteinase falcipain 2b 0.0019 0.002 0.0932
Trypanosoma cruzi beta-ketoacyl synthase family protein, putative 0.0012 0.0002 0.0018
Trypanosoma brucei DNA polymerase kappa, putative 0.0022 0.0029 0.0828
Echinococcus granulosus thyrotropin releasing hormone receptor 0.0052 0.0114 0.0117
Schistosoma mansoni ferritin light chain 0.0015 0.0009 0.0008
Schistosoma mansoni peptide (FMRFamide/somatostatin)-like receptor 0.0052 0.0114 0.0117
Brugia malayi Importin beta-1 subunit 0.0084 0.0204 0.0234
Echinococcus multilocularis serine:threonine protein kinase PLK1 0.0127 0.0322 0.0321
Trichomonas vaginalis chromobox protein, putative 0.0033 0.0059 0.0265
Brugia malayi Beta-ketoacyl synthase, N-terminal domain containing protein 0.0048 0.0103 0.0117
Brugia malayi Pyridine nucleotide-disulphide oxidoreductase, dimerisation domain containing protein 0.0019 0.0021 0.0022
Schistosoma mansoni cpg binding protein 0.0024 0.0036 0.0036
Echinococcus granulosus lysine specific demethylase 6a 0.0016 0.0013 0.0012
Trypanosoma cruzi STE/STE11 serine/threonine-protein kinase, putative 0.0026 0.004 0.116
Brugia malayi Nuclear hormone receptor family member nhr-49 0.0013 0.0004 0.0002
Echinococcus granulosus cathepsin L cysteine proteinase 0.0019 0.002 0.002
Loa Loa (eye worm) fatty acid synthase 0.0048 0.0101 0.0115
Onchocerca volvulus 0.0131 0.0335 0.1563
Onchocerca volvulus 0.0052 0.0114 0.0523
Onchocerca volvulus Serine\/threonine kinase homolog 0.0127 0.0322 0.1503
Brugia malayi Dopamine receptor 0.0052 0.0114 0.013
Loa Loa (eye worm) hypothetical protein 0.0013 0.0004 0.0002
Trypanosoma cruzi cysteine peptidase, clan CA, family C1, cathepsin L-like, putative 0.0065 0.0149 0.4441
Trichomonas vaginalis Importin beta-1 subunit, putative 0.0068 0.0159 0.0735
Giardia lamblia Flap structure-specific endonuclease 0.0018 0.0019 0.0323
Echinococcus granulosus fmrfamide receptor 0.0052 0.0114 0.0117
Echinococcus granulosus G protein coupled receptor 139 0.0052 0.0114 0.0117
Schistosoma mansoni amine GPCR 0.0052 0.0114 0.0117
Echinococcus granulosus cathepsin l cysteine peptidase 0.0019 0.002 0.002
Echinococcus granulosus neuropeptides capa receptor 0.0052 0.0114 0.0117
Plasmodium falciparum dihydrolipoyl dehydrogenase, mitochondrial 0.0026 0.004 0.193
Loa Loa (eye worm) jmjC domain-containing protein 0.0063 0.0144 0.0165
Entamoeba histolytica hypothetical protein 0.0029 0.005 0.1198
Trichomonas vaginalis importin beta-1, putative 0.0068 0.0159 0.0735
Echinococcus multilocularis tm gpcr rhodopsin gpcr rhodopsin superfamily 0.0052 0.0114 0.0113
Brugia malayi Papain family cysteine protease containing protein 0.0019 0.002 0.0021
Mycobacterium tuberculosis Possible penicillin-binding protein 0.0839 0.231 1
Giardia lamblia Kinase, PLK 0.0127 0.0322 1
Plasmodium vivax flap endonuclease 1, putative 0.0018 0.0019 0.0508
Trichomonas vaginalis chromodomain helicase DNA binding protein, putative 0.0013 0.0006 0.0012
Echinococcus multilocularis PHD finger protein rhinoceros 0.0031 0.0053 0.0052
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0019 0.002 0.0081
Schistosoma mansoni metabotropic glutamate receptor 0.0141 0.0361 0.0374
Plasmodium falciparum glutathione reductase 0.0026 0.004 0.193
Loa Loa (eye worm) hypothetical protein 0.0052 0.0114 0.013
Loa Loa (eye worm) hypothetical protein 0.0052 0.0114 0.013
Echinococcus multilocularis guanine nucleotide binding protein G(s) subunit 0.0016 0.0013 0.0011
Echinococcus multilocularis importin subunit beta 1 0.0084 0.0204 0.0202
Echinococcus granulosus g-protein coupled receptor 0.0052 0.0114 0.0117
Brugia malayi Unidentified vitellogenin-linked transcript protein 6, putative 0.0052 0.0114 0.013
Brugia malayi metabotropic GABA-B receptor subtype 2 0.0029 0.005 0.0056
Toxoplasma gondii kinesin motor domain-containing protein 0.0016 0.0011 0.0292
Loa Loa (eye worm) bromodomain containing protein 0.0031 0.0054 0.006
Loa Loa (eye worm) flap endonuclease-1 0.0018 0.0019 0.002
Trichomonas vaginalis cat eye syndrome critical region protein 2, cscr2, putative 0.0027 0.0045 0.0197
Brugia malayi MH2 domain containing protein 0.0098 0.0241 0.0278
Echinococcus granulosus g protein linked acetylcholine receptor gar 2a 0.0052 0.0114 0.0117
Onchocerca volvulus 0.0052 0.0114 0.0523
Schistosoma mansoni hypothetical protein 0.3452 0.9607 1
Schistosoma mansoni tar DNA-binding protein 0.0123 0.0312 0.0323
Loa Loa (eye worm) acetyltransferase 0.0084 0.0203 0.0234
Brugia malayi G-protein coupled receptor 0.0052 0.0114 0.013
Trypanosoma brucei importin beta-1 subunit, putative 0.0084 0.0204 0.6066
Echinococcus multilocularis mothers against decapentaplegic 2 0.0044 0.009 0.0089
Schistosoma mansoni acetylcholinesterase 0.0026 0.004 0.0041
Mycobacterium tuberculosis Possible DNA-damage-inducible protein P DinP (DNA polymerase V) (pol IV 2) (DNA nucleotidyltransferase (DNA-directed)) 0.0022 0.0029 0.0121
Echinococcus granulosus tumor protein p63 0.0924 0.2547 0.265
Schistosoma mansoni histamine-responsive GPCR (AAF21638) 0.0052 0.0114 0.0117
Brugia malayi Steroid receptor seven-up type 2 0.0013 0.0004 0.0002
Echinococcus multilocularis JmjC domain containing protein 4 0.0016 0.0013 0.0012
Trichomonas vaginalis spcc417.12 protein, putative 0.0026 0.004 0.0176
Echinococcus multilocularis rhodopsin orphan GPCR 0.0052 0.0114 0.0113
Mycobacterium leprae PHENOLPTHIOCEROL SYNTHESIS TYPE-I POLYKETIDE SYNTHASE PPSB 0.0039 0.0077 0.1384
Echinococcus multilocularis sex peptide receptor 0.0052 0.0114 0.0113
Trichomonas vaginalis Clan CA, family C1, papain-like cysteine peptidase 0.0019 0.002 0.0081
Mycobacterium ulcerans glutamine-binding lipoprotein GlnH 0.0014 0.0007 0.0149
Echinococcus granulosus TGF beta signal transducer SmadC 0.0098 0.0241 0.025
Trichomonas vaginalis ran, putative 0.0055 0.0121 0.0558
Mycobacterium ulcerans bacterioferritin BfrB 0.0015 0.0009 0.0216
Loa Loa (eye worm) hypothetical protein 0.0026 0.004 0.0045
Entamoeba histolytica protein kinase domain containing protein 0.011 0.0274 0.6539
Toxoplasma gondii HEAT repeat-containing protein 0.0016 0.0013 0.0328
Echinococcus multilocularis Transcription factor, JmjC domain containing protein 0.0124 0.0314 0.0312
Trypanosoma cruzi major cysteine proteinase, putative 0.0056 0.0124 0.3683
Trichomonas vaginalis D-aminoacylase, putative 0.0131 0.0335 0.1563
Entamoeba histolytica deoxycytidyl transferase, putative 0.0022 0.0029 0.0693
Echinococcus multilocularis dual specificity 0.011 0.0274 0.0273
Loa Loa (eye worm) hypothetical protein 0.0131 0.0335 0.0386
Brugia malayi Cathepsin L-like cysteine proteinase 0.0012 0.0003 0.0001
Trichomonas vaginalis Clan CA, family C1, papain-like cysteine peptidase 0.0019 0.002 0.0081
Onchocerca volvulus 0.0029 0.005 0.0222
Toxoplasma gondii flap structure-specific endonuclease 1, putative 0.0018 0.0019 0.0509
Schistosoma mansoni alpha-1 adrenergic receptor 0.0052 0.0114 0.0117
Mycobacterium ulcerans DNA polymerase III subunit alpha 0.0101 0.025 0.7439
Echinococcus granulosus FTZ F1 alpha 0.0013 0.0004 0.0002
Loa Loa (eye worm) hypothetical protein 0.0027 0.0044 0.0048
Trypanosoma cruzi dihydrolipoamide dehydrogenase, putative 0.0026 0.004 0.1171
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0019 0.002 0.0081
Brugia malayi hypothetical protein 0.0052 0.0114 0.013
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0052 0.0114 0.0117
Schistosoma mansoni jumonji domain containing protein 0.0016 0.0013 0.0012
Toxoplasma gondii MAPEG family protein 0.0135 0.0345 1
Echinococcus granulosus hypothetical protein 0.0832 0.229 0.2382
Brugia malayi ecdysteroid receptor 0.0013 0.0004 0.0002
Loa Loa (eye worm) aryl Hydrocarbon receptor Associated protein family member 0.0055 0.0122 0.0139
Leishmania major 2-oxoglutarate dehydrogenase, e3 component, lipoamidedehydrogenase-like protein 0.0026 0.004 0.1171
Plasmodium falciparum 3-oxoacyl-acyl-carrier protein synthase I/II 0.0012 0.0002 0.003
Brugia malayi map kinase activated protein kinase protein 2 0.3096 0.8612 1
Trypanosoma brucei ULK family serine/threonine-protein kinase, putative 0.0025 0.0039 0.1116
Trypanosoma brucei DNA polymerase kappa, putative 0.0022 0.0029 0.0828
Echinococcus granulosus dro:myosuppressin receptor 0.0052 0.0114 0.0117
Mycobacterium tuberculosis Hypothetical protein 0.0015 0.0009 0.0033
Mycobacterium tuberculosis Conserved protein 0.0131 0.0335 0.1445
Entamoeba histolytica cysteine proteinase, putative 0.0019 0.002 0.0484
Schistosoma mansoni protein kinase 0.0032 0.0058 0.0058
Echinococcus multilocularis dihydrolipoamide dehydrogenase 0.0026 0.004 0.0039
Trypanosoma cruzi dihydrolipoamide dehydrogenase, putative 0.0026 0.004 0.1171
Echinococcus multilocularis mothers against decapentaplegic 5 0.0098 0.0241 0.024
Brugia malayi Latrophilin receptor protein 2 0.0241 0.064 0.0741
Brugia malayi Bromodomain containing protein 0.0125 0.0318 0.0367
Trypanosoma cruzi importin beta-1 subunit, putative 0.0068 0.0159 0.473
Echinococcus multilocularis tm gpcr rhodopsin gpcr rhodopsin superfamily 0.0052 0.0114 0.0113
Echinococcus multilocularis fmrfamide receptor 0.0052 0.0114 0.0113
Schistosoma mansoni family S9 non-peptidase homologue (S09 family) 0.0026 0.004 0.0041
Echinococcus multilocularis cathepsin l cysteine peptidase 0.0019 0.002 0.0019
Echinococcus granulosus neuropeptide Y receptor 0.0052 0.0114 0.0117
Schistosoma mansoni eyes absent homolog 0.0045 0.0094 0.0096
Brugia malayi AMP-binding enzyme family protein 0.0045 0.0094 0.0107
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0052 0.0114 0.0117
Loa Loa (eye worm) hypothetical protein 0.0013 0.0004 0.0002
Echinococcus multilocularis orexin receptor type 2 0.0052 0.0114 0.0113
Echinococcus multilocularis jumonji domain containing protein 0.0043 0.0087 0.0085
Loa Loa (eye worm) CHromoDomain protein family member 0.0013 0.0005 0.0003
Trypanosoma brucei DNA polymerase kappa, putative 0.0015 0.001 0.0261
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0071 0.0167 0.4958
Plasmodium falciparum ataxin-2 like protein, putative 0.0065 0.015 0.7353
Schistosoma mansoni ran 0.0055 0.0121 0.0125
Echinococcus multilocularis TGF beta signal transducer SmadC 0.0098 0.0241 0.024
Loa Loa (eye worm) camk/mapkapk/mapkapk protein kinase 0.3096 0.8612 1
Echinococcus multilocularis zinc finger protein 0.0035 0.0066 0.0064
Toxoplasma gondii AMP-binding enzyme domain-containing protein 0.0024 0.0036 0.1015
Echinococcus granulosus Glutamate receptor ionotropic kainate 2 0.0035 0.0065 0.0067
Schistosoma mansoni phosphatidylserine receptor 0.0016 0.0013 0.0012
Mycobacterium tuberculosis Polyketide synthetase MbtC (polyketide synthase) 0.0017 0.0015 0.0058
Brugia malayi hypothetical protein 0.0038 0.0075 0.0085
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0052 0.0114 0.0117
Toxoplasma gondii histone lysine acetyltransferase GCN5-A 0.0027 0.0045 0.1264
Mycobacterium tuberculosis Phenolpthiocerol synthesis type-I polyketide synthase PpsA 0.0048 0.0103 0.0442
Brugia malayi hypothetical protein 0.0052 0.0114 0.013
Echinococcus granulosus JmjC domain containing protein 4 0.0016 0.0013 0.0012
Brugia malayi nuclear receptor NHR-88 0.0013 0.0004 0.0002
Leishmania major hypothetical protein, conserved 0.0131 0.0335 1
Schistosoma mansoni flap endonuclease-1 0.0016 0.0014 0.0013
Brugia malayi beta-lactamase 0.0131 0.0335 0.0386
Loa Loa (eye worm) hypothetical protein 0.0052 0.0114 0.013
Echinococcus multilocularis microtubule associated protein 2 0.2208 0.6134 0.6133
Trypanosoma cruzi dihydrolipoamide dehydrogenase, putative 0.0026 0.004 0.1171
Echinococcus granulosus carboxylesterase 5A 0.0153 0.0396 0.041
Trichomonas vaginalis conserved hypothetical protein 0.0015 0.0009 0.0027
Trichomonas vaginalis conserved hypothetical protein 0.0016 0.0014 0.0052
Loa Loa (eye worm) hypothetical protein 0.0052 0.0114 0.013
Onchocerca volvulus 0.0026 0.004 0.0176
Schistosoma mansoni protein phosphatase 2C 0.0016 0.0013 0.0012
Entamoeba histolytica Flap nuclease, putative 0.0018 0.0019 0.0452
Loa Loa (eye worm) hypothetical protein 0.0065 0.015 0.0172
Onchocerca volvulus 0.0052 0.0114 0.0523
Schistosoma mansoni membrane associated proteins in eicosanoid and glutathione metabolism family member 0.059 0.1615 0.1679
Trypanosoma cruzi JmjC domain, hydroxylase, putative 0.0016 0.0013 0.0359
Echinococcus granulosus biogenic amine 5HT receptor 0.0052 0.0114 0.0117
Trichomonas vaginalis adenylate and guanylate cyclases, putative 0.0016 0.0014 0.0052
Echinococcus multilocularis peregrin 0.0036 0.007 0.0068
Brugia malayi Serotonin receptor 0.0052 0.0114 0.013
Trypanosoma cruzi tyrosyl-DNA Phosphodiesterase (Tdp1), putative 0.0049 0.0105 0.3101
Echinococcus granulosus Glutamate receptor ionotropic kainate 2 0.0035 0.0065 0.0067
Echinococcus multilocularis methyl CpG binding domain protein 2 0.0028 0.0046 0.0044
Echinococcus granulosus fetal alzheimer antigen falz 0.0038 0.0074 0.0075
Mycobacterium tuberculosis Probable oxidoreductase 0.0189 0.0497 0.2148
Mycobacterium ulcerans carboxylesterase, LipT 0.0026 0.004 0.1153
Onchocerca volvulus 0.0107 0.0266 0.1238
Entamoeba histolytica kinesin, putative 0.0016 0.0011 0.0274
Mycobacterium tuberculosis Probable soluble pyridine nucleotide transhydrogenase SthA (STH) (NAD(P)(+) transhydrogenase [B-specific]) (nicotinamide nucleot 0.0026 0.004 0.017
Brugia malayi neuropeptide F receptor 0.0052 0.0114 0.013
Leishmania major hypothetical protein, conserved 0.0015 0.0009 0.0222
Loa Loa (eye worm) nuclear hormone receptor family member nhr-49 0.0013 0.0004 0.0002
Brugia malayi aryl hydrocarbon receptor nuclear translocator protein, putative 0.0039 0.0076 0.0086
Echinococcus granulosus phd:f box containing protein 0.0016 0.0013 0.0012
Trypanosoma cruzi PAS-domain containing phosphoglycerate kinase, putative 0.0016 0.0014 0.0383
Brugia malayi AKH receptor 0.0052 0.0114 0.013
Brugia malayi Dopamine receptor protein 2 0.0052 0.0114 0.013
Echinococcus granulosus methyl CpG binding domain protein 2 0.0028 0.0046 0.0046
Wolbachia endosymbiont of Brugia malayi bacterioferritin/cytochrome b1 0.0015 0.0009 0.029
Trypanosoma brucei flap endonuclease-1 (FEN-1), putative 0.0018 0.0019 0.0525
Brugia malayi Nuclear hormone receptor family member nhr-1 0.0013 0.0004 0.0002
Schistosoma mansoni amine GPCR 0.0052 0.0114 0.0117
Echinococcus granulosus chromobox protein 1 0.0054 0.0119 0.0123
Echinococcus multilocularis biogenic amine (5HT) receptor 0.0825 0.2271 0.227
Echinococcus multilocularis rhodopsin orphan GPCR 0.0052 0.0114 0.0113
Brugia malayi Pre-SET motif family protein 0.0098 0.0241 0.0278
Brugia malayi MH1 domain containing protein 0.0098 0.0241 0.0278
Loa Loa (eye worm) PLK/PLK1 protein kinase 0.0127 0.0322 0.0372
Schistosoma mansoni methyl-cpg binding protein mbd 0.0028 0.0046 0.0046
Echinococcus multilocularis dna polymerase kappa 0.0022 0.0029 0.0028
Trichomonas vaginalis chromobox protein, putative 0.0054 0.0119 0.0548
Schistosoma mansoni tyrosyl-DNA phosphodiesterase 0.0049 0.0105 0.0108
Mycobacterium leprae PROBABLE DNA POLYMERASE III (ALPHA CHAIN) DNAE1 (DNA NUCLEOTIDYLTRANSFERASE) 0.0101 0.0251 0.4955
Schistosoma mansoni tar DNA-binding protein 0.0123 0.0312 0.0323
Loa Loa (eye worm) hypothetical protein 0.0081 0.0195 0.0224
Mycobacterium ulcerans dihydrolipoamide dehydrogenase, LpdB 0.0026 0.004 0.1155
Echinococcus granulosus receptor type guanylyl cyclase 0.0032 0.0058 0.0058
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0071 0.0167 0.4958
Echinococcus multilocularis acetylcholinesterase 0.0153 0.0396 0.0394
Mycobacterium tuberculosis Probable dehydrogenase 0.017 0.0444 0.1918
Brugia malayi hypothetical protein 0.0137 0.0352 0.0406
Trypanosoma brucei DNA polymerase IV, putative 0.0022 0.0029 0.0828
Echinococcus granulosus allatostatin A receptor 0.0052 0.0114 0.0117
Leishmania major protein kinase, putative,polo-like protein kinase, putative 0.0127 0.0322 0.9618
Brugia malayi hypothetical protein 0.0383 0.1037 0.1202
Schistosoma mansoni Smad4 0.0044 0.009 0.0093
Trichomonas vaginalis mercuric reductase, putative 0.0026 0.004 0.0176
Echinococcus granulosus g protein linked acetylcholine receptor gar 2a 0.0052 0.0114 0.0117
Schistosoma mansoni jumonji/arid domain-containing protein 0.0065 0.015 0.0154
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0071 0.0167 0.4958
Echinococcus multilocularis Glutamate receptor, ionotropic kainate 2 0.0035 0.0065 0.0064
Brugia malayi jmjC domain containing protein 0.0016 0.0013 0.0013
Schistosoma mansoni cpg binding protein 0.002 0.0024 0.0024
Echinococcus granulosus 7tm_1 domain containing protein 0.0052 0.0114 0.0117
Toxoplasma gondii thioredoxin reductase 0.0075 0.0177 0.5097
Echinococcus granulosus bromodomain adjacent to zinc finger domain 0.0059 0.0132 0.0135
Echinococcus multilocularis microsomal glutathione S transferase 3 0.0135 0.0345 0.0344
Echinococcus granulosus kinesin family 1 0.0119 0.0301 0.0312
Mycobacterium leprae Probable polyketide synthase Pks1 0.0051 0.0111 0.2096
Mycobacterium tuberculosis Polyketide synthase Pks12 0.0051 0.0111 0.0478
Entamoeba histolytica hypothetical protein 0.011 0.0274 0.6539
Schistosoma mansoni histone-lysine n-methyltransferase setb1 0.0098 0.0241 0.0249
Onchocerca volvulus 0.0013 0.0004 0.0003
Echinococcus granulosus orexin receptor type 2 0.0052 0.0114 0.0117
Schistosoma mansoni hypothetical protein 0.0241 0.064 0.0665
Loa Loa (eye worm) hypothetical protein 0.0055 0.0121 0.0139
Echinococcus multilocularis tyrosine kinase 0.0032 0.0058 0.0056
Mycobacterium ulcerans phenolpthiocerol synthesis type-I polyketide synthase PpsE 0.0032 0.0057 0.1664
Mycobacterium tuberculosis Putative ferredoxin reductase 0.017 0.0444 0.1918
Loa Loa (eye worm) hypothetical protein 0.0013 0.0004 0.0002
Brugia malayi Serotonin/octopamine receptor family protein 7 0.0272 0.0728 0.0843
Mycobacterium tuberculosis NAD(P)H quinone reductase LpdA 0.0189 0.0497 0.2148
Loa Loa (eye worm) hypothetical protein 0.0052 0.0114 0.013
Toxoplasma gondii LsmAD domain-containing protein 0.0065 0.015 0.4321
Loa Loa (eye worm) hypothetical protein 0.0052 0.0114 0.013
Echinococcus multilocularis geminin 0.3452 0.9607 0.9607
Mycobacterium ulcerans dihydrolipoamide dehydrogenase 0.0026 0.004 0.1155
Schistosoma mansoni gcn5proteinral control of amino-acid synthesis 5-like 2 gcnl2 0.0084 0.0203 0.021
Treponema pallidum NADH oxidase 0.0026 0.004 0.1151
Brugia malayi serine/threonine-protein kinase plk-2 0.0127 0.0322 0.0372
Brugia malayi PAS domain containing protein 0.0016 0.0014 0.0014
Trichomonas vaginalis fructose-bisphosphate aldolase, putative 0.0118 0.0298 0.1389
Brugia malayi cathepsin L-like precursor 0.0012 0.0003 0.0001
Loa Loa (eye worm) hypothetical protein 0.0013 0.0004 0.0002
Schistosoma mansoni peptidase 0.0015 0.001 0.0009
Schistosoma mansoni ferritin 0.0015 0.0009 0.0008
Mycobacterium tuberculosis Probable fatty acid synthase Fas (fatty acid synthetase) 0.0015 0.0011 0.0041
Loa Loa (eye worm) jmjC domain-containing protein 0.0016 0.0013 0.0013
Wolbachia endosymbiont of Brugia malayi DNA polymerase III alpha subunit 0.0101 0.025 1
Trichomonas vaginalis carboxylesterase domain containing protein, putative 0.0026 0.004 0.0176
Brugia malayi metabotropic GABA-B receptor subtype 2 0.0046 0.0096 0.011
Echinococcus multilocularis metabotropic glutamate receptor 2 0.024 0.0638 0.0636
Loa Loa (eye worm) hypothetical protein 0.0059 0.0132 0.0151
Loa Loa (eye worm) hypothetical protein 0.0075 0.0178 0.0205
Onchocerca volvulus 0.0052 0.0114 0.0523
Echinococcus multilocularis cathepsin L cysteine protease 0.0019 0.002 0.0019
Plasmodium vivax importin-beta 2, putative 0.0084 0.0204 0.6059
Brugia malayi hypothetical protein 0.0065 0.015 0.0172
Loa Loa (eye worm) hypothetical protein 0.0115 0.029 0.0334
Mycobacterium leprae PHENOLPTHIOCEROL SYNTHESIS TYPE-I POLYKETIDE SYNTHASE PPSD 0.0048 0.0103 0.1924
Trichomonas vaginalis Importin beta-1 subunit, putative 0.0068 0.0159 0.0735
Echinococcus multilocularis fmrfamide receptor 0.0052 0.0114 0.0113
Schistosoma mansoni hypothetical protein 0.0052 0.0114 0.0117
Echinococcus granulosus 7TM GPCR rhodopsin 0.0052 0.0114 0.0117
Trichomonas vaginalis chromodomain helicase DNA binding protein, putative 0.0013 0.0006 0.0012
Mycobacterium tuberculosis Conserved protein 0.0131 0.0335 0.1445
Mycobacterium ulcerans Type I modular polyketide synthase 0.0048 0.0103 0.3037
Loa Loa (eye worm) hypothetical protein 0.0131 0.0335 0.0386
Brugia malayi hypothetical protein 0.0029 0.005 0.0056
Loa Loa (eye worm) ImpB/MucB/SamB family protein 0.0022 0.0029 0.0031
Echinococcus multilocularis transportin 1 0.0016 0.0013 0.0011
Echinococcus multilocularis family S9 non peptidase ue (S09 family) 0.0026 0.004 0.0039
Loa Loa (eye worm) carboxylesterase 0.0026 0.004 0.0045
Echinococcus multilocularis ecdysone induced protein 78C 0.0013 0.0004 0.0002
Loa Loa (eye worm) hypothetical protein 0.0153 0.0396 0.0457
Loa Loa (eye worm) hypothetical protein 0.0825 0.2273 0.2637
Onchocerca volvulus 0.0052 0.0114 0.0523
Schistosoma mansoni hypothetical protein 0.0046 0.0096 0.0099
Loa Loa (eye worm) fibroinase 0.0019 0.002 0.0021
Leishmania major acetoin dehydrogenase e3 component-like protein 0.0026 0.004 0.1171
Echinococcus granulosus lysine specific demethylase 5A 0.0065 0.015 0.0154
Trichomonas vaginalis D-aminoacylase, putative 0.0131 0.0335 0.1563
Loa Loa (eye worm) hypothetical protein 0.0026 0.004 0.0045
Echinococcus multilocularis translational activator gcn1 0.0016 0.0013 0.0011
Schistosoma mansoni thyroid hormone receptor 0.0013 0.0004 0.0002
Trichomonas vaginalis Clan CA, family C1, papain-like cysteine peptidase 0.0019 0.002 0.0081
Trypanosoma cruzi STE/STE11 serine/threonine-protein kinase, putative 0.0026 0.004 0.116
Echinococcus multilocularis nmda type glutamate receptor 0.0019 0.0022 0.0021
Echinococcus granulosus Glutamate receptor ionotropic kainate 2 0.0035 0.0065 0.0067

Activities

Activity type Activity value Assay description Source Reference
IC50 (binding) = 5 nM BindingDB_Patents: Enzyme Assay. The aim of this assay is to determine the affinity of a test compound for the mPGES-1 enzyme. 47 µl of recombinant human mPGES-1 (0.5 µg protein/well) containing microsomal suspension in a buffer containing GSH, (2.5 mmol/L L-Glutathione reduced, dissolved in 0.1 mol/L Phosphat Buffer pH 7.4) is dispensed in a 384-well plate and thereafter 1 µl of the test compound(s) is/are added and incubated for 25 minutes at room temperature. The enzyme reaction is started by the addition of 2 ul PGH2 (final conc 2 µM) disolved in water-free Diglyme. After 60 seconds the reaction is terminated by addition of a stop solution containing FeCl2 (10 µL 0.074 mol/l FeCl2). The samples are diluted between 1:25 in PBS (Phosphate Buffered Saline). 10 µl of the diluted samples are transferred to 384-well low volume plate. ChEMBL. No reference

Phenotypes

Whole-cell/tissue/organism interactions

We have no records of whole-cell/tissue assays done with this compound What does this mean?

Many chemical entities in TDR Targets come from high-throughput screenings with whole cells or tissue samples, and not all assayed compounds have been tested against a single a single target protein, probably because they get ruled out during screening process. Even if these compounds may have not been of interest in the original screening, they may come as interesting leads for other screening assays. Furthermore, we may be able to propose drug-target associations using chemical similarities and network patterns.

Annotated phenotypes:

We have no manually annotated phenotypes for this drug. What does this mean? / Care to help?
In TDR Targets, information about phenotypes that are caused by drugs, or by genetic manipulation of cells (e.g. gene knockouts or knockdowns) is manually curated from the literature. These descriptions help to describe the potential of the target for drug development. If no information is available for this gene or if the information is incomplete, this may mean that i) the papers containing this information either appeared after the curation effort for this organism was carried out or they were inadvertently missed by curators; or that ii) the curation effort for this organism has not yet started.
 
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External resources for this compound

Bibliographic References

No literature references available for this target.

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