Detailed information for compound 209696

Basic information

Technical information
  • TDR Targets ID: 209696
  • Name: 1,6-bis[(3-fluorophenyl)methoxy]-2,5-bis(phen ylmethoxy)hexane-3,4-diol
  • MW: 578.643 | Formula: C34H36F2O6
  • H donors: 2 H acceptors: 2 LogP: 4.71 Rotable bonds: 17
    Rule of 5 violations (Lipinski): 2
  • SMILES: OC(C(C(OCc1ccccc1)COCc1cccc(c1)F)O)C(OCc1ccccc1)COCc1cccc(c1)F
  • InChi: 1S/C34H36F2O6/c35-29-15-7-13-27(17-29)19-39-23-31(41-21-25-9-3-1-4-10-25)33(37)34(38)32(42-22-26-11-5-2-6-12-26)24-40-20-28-14-8-16-30(36)18-28/h1-18,31-34,37-38H,19-24H2
  • InChiKey: CYVVVZDRTDJNNU-UHFFFAOYSA-N  


Substructure search Similarity search

Network

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Synonyms

  • 2,5-dibenzyloxy-1,6-bis[(3-fluorophenyl)methoxy]hexane-3,4-diol
  • 2,5-dibenzoxy-1,6-bis[(3-fluorobenzyl)oxy]hexane-3,4-diol
  • 2,5-bis(benzyloxy)-1,6-bis[(3-fluorobenzyl)oxy]hexane-3,4-diol

Targets

Known targets for this compound

Species Target name Source Bibliographic reference
Human immunodeficiency virus 1 Human immunodeficiency virus type 1 protease Starlite/ChEMBL References

Predicted pathogen targets for this compound

By orthology
Species Potential target Known druggable target/s Ortholog Group
Schistosoma mansoni intracisternal A-particle retropepsin (A02 family) Get druggable targets OG5_131408 All targets in OG5_131408
By sequence similarity to non orthologous known druggable targets
Species Potential target Known druggable target Length Alignment span Identity
Candida albicans dethiobiotin synthetase Human immunodeficiency virus type 1 protease   99 aa 90 aa 22.2 %
Trypanosoma brucei variant surface glycoprotein (VSG), putative Human immunodeficiency virus type 1 protease   99 aa 80 aa 27.5 %
Entamoeba histolytica retroviral aspartyl protease domain-containing protein Human immunodeficiency virus type 1 protease   99 aa 103 aa 31.1 %
Candida albicans dethiobiotin synthetase Human immunodeficiency virus type 1 protease   99 aa 90 aa 22.2 %
Giardia lamblia DNA-directed RNA polymerase subunit D Human immunodeficiency virus type 1 protease   99 aa 90 aa 27.8 %
Mycobacterium leprae Hypothetical protein Human immunodeficiency virus type 1 protease   99 aa 86 aa 27.9 %
Entamoeba histolytica retroviral aspartyl protease domain-containing protein Human immunodeficiency virus type 1 protease   99 aa 103 aa 31.1 %
Echinococcus multilocularis Chromobox protein 3 Human immunodeficiency virus type 1 protease   99 aa 95 aa 28.4 %
Obtained from network model

Ranking Plot

Putative Targets List

Species Potential target Raw Global Species
Loa Loa (eye worm) thioredoxin reductase 0.0047 0.0032 0.0032
Schistosoma mansoni sodium/chloride dependent transporter 0.0535 0.0647 0.0646
Onchocerca volvulus Dopamine\/Ecdysteroid receptor homolog 0.0109 0.0111 0.0333
Echinococcus granulosus NDR protein kinase 0.0237 0.0272 0.0271
Brugia malayi Protein kinase domain containing protein 0.0219 0.0248 0.0248
Entamoeba histolytica exodeoxyribonuclease III, putative 0.0056 0.0044 0.0834
Loa Loa (eye worm) hypothetical protein 0.0035 0.0017 0.0017
Plasmodium falciparum transporter, putative 0.0091 0.0088 0.0087
Brugia malayi Neurotransmitter-gated ion-channel transmembrane region family protein 0.0027 0.0007 0.0007
Echinococcus multilocularis glycine receptor subunit alpha 1 0.005 0.0036 0.0036
Echinococcus granulosus rhodopsin orphan GPCR 0.0109 0.0111 0.011
Schistosoma mansoni growth hormone secretagogue receptor 0.0109 0.0111 0.011
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0109 0.0111 0.011
Brugia malayi beta-lactamase family protein 0.0035 0.0017 0.0017
Mycobacterium tuberculosis Probable lipase LipE 0.0035 0.0017 0.0341
Brugia malayi Acetylcholine receptor protein, alpha-like chain 1 precursor 0.0023 0.0002 0.0002
Schistosoma mansoni peptide (allatostatin/somatostatin)-like receptor 0.0109 0.0111 0.011
Loa Loa (eye worm) glutamate receptor 1 0.0144 0.0155 0.0155
Echinococcus multilocularis rhodopsin orphan GPCR 0.0109 0.0111 0.011
Loa Loa (eye worm) hypothetical protein 0.012 0.0125 0.0124
Plasmodium vivax SET domain protein, putative 0.0029 0.0011 0.001
Loa Loa (eye worm) hypothetical protein 0.005 0.0036 0.0036
Loa Loa (eye worm) intermediate filament protein 0.0026 0.0007 0.0006
Loa Loa (eye worm) hypothetical protein 0.0212 0.024 0.024
Echinococcus granulosus neuropeptide Y receptor 0.0109 0.0111 0.011
Schistosoma mansoni glutamate receptor AMPA 0.0144 0.0155 0.0155
Brugia malayi beta-lactamase 0.0035 0.0017 0.0017
Trichomonas vaginalis glucosylceramidase, putative 0.0164 0.0179 0.6236
Plasmodium falciparum topoisomerase I 0.7972 1 1
Echinococcus multilocularis serotonin receptor 0.0109 0.0111 0.011
Treponema pallidum sodium- and chloride- dependent transporter 0.0535 0.0647 1
Loa Loa (eye worm) hypothetical protein 0.0023 0.0002 0.0002
Echinococcus granulosus Cys loop ligand gated ion channel subunit 0.005 0.0036 0.0036
Echinococcus granulosus uncharacterized sodium dependent transporter 0.0091 0.0088 0.0087
Brugia malayi Tachykinin-like peptides receptor 99D 0.0109 0.0111 0.0111
Schistosoma mansoni intermediate filament proteins 0.0026 0.0007 0.0006
Echinococcus granulosus glutamate receptor ionotropic kainate 3 0.0053 0.0041 0.004
Loa Loa (eye worm) hypothetical protein 0.0109 0.0111 0.011
Onchocerca volvulus 0.0109 0.0111 0.0333
Echinococcus granulosus arachidonate 5 lipoxygenase 0.012 0.0124 0.0124
Echinococcus multilocularis peptide (allatostatin:somatostatin) 0.0109 0.0111 0.011
Echinococcus granulosus 7tm_1 domain containing protein 0.0109 0.0111 0.011
Echinococcus granulosus g protein coupled receptor 0.0109 0.0111 0.011
Brugia malayi hypothetical protein 0.0109 0.0111 0.0111
Schistosoma mansoni glutamate receptor AMPA 0.0144 0.0155 0.0155
Schistosoma mansoni neuropeptide receptor 0.0109 0.0111 0.011
Entamoeba histolytica diacylglycerol kinase, putative 0.0212 0.024 0.4631
Loa Loa (eye worm) hypothetical protein 0.0109 0.0111 0.011
Loa Loa (eye worm) DNA topoisomerase I 0.7972 1 1
Echinococcus multilocularis rhodopsin orphan GPCR 0.0109 0.0111 0.011
Mycobacterium tuberculosis Probable hydrolase 0.0035 0.0017 0.0341
Trichomonas vaginalis DNA helicase recq, putative 0.0022 0.0002 0.0044
Schistosoma mansoni nAChR subunit (ShAR1-beta-like) 0.012 0.0125 0.0124
Brugia malayi gamma-aminobutyric-acid receptor beta subunit precursor 0.005 0.0036 0.0036
Echinococcus multilocularis nicotinic acetylcholine receptor subunit type 0.0023 0.0002 0.0002
Schistosoma mansoni blooms syndrome DNA helicase 0.0033 0.0015 0.0015
Trichomonas vaginalis glucosylceramidase, putative 0.0164 0.0179 0.6236
Loa Loa (eye worm) Sodium:neurotransmitter symporter family protein 0.0091 0.0088 0.0087
Schistosoma mansoni vesicular acetylcholine transporter 0.2661 0.332 0.332
Echinococcus granulosus G protein coupled receptor 139 0.0109 0.0111 0.011
Echinococcus multilocularis glutamate receptor ionotropic kainate 0.0053 0.0041 0.004
Echinococcus granulosus glutamate NMDA receptor subunit 0.0307 0.0359 0.0359
Onchocerca volvulus 0.059 0.0716 0.2154
Echinococcus granulosus rhodopsin orphan GPCR 0.0109 0.0111 0.011
Entamoeba histolytica protein kinase, putative 0.0028 0.0009 0.0157
Echinococcus multilocularis C2 calcium dependent membrane targeting 0.0234 0.0267 0.0267
Schistosoma mansoni biogenic amine (dopamine) receptor 0.0109 0.0111 0.011
Trypanosoma cruzi Lanosterol 14-alpha demethylase 0.0028 0.0009 0.0011
Loa Loa (eye worm) STE/STE11/MEKK2 protein kinase 0.0025 0.0004 0.0004
Brugia malayi RNA recognition motif domain containing protein 0.0062 0.0052 0.0052
Echinococcus multilocularis diuretic hormone 44 receptor GPRdih2 0.0031 0.0013 0.0013
Onchocerca volvulus 0.0091 0.0088 0.0263
Brugia malayi Neuronal acetylcholine receptor protein, alpha-2 chain precursor 0.0023 0.0002 0.0002
Echinococcus multilocularis rhodopsin orphan GPCR 0.0109 0.0111 0.011
Mycobacterium tuberculosis Inositol-1-monophosphatase SuhB 0.0032 0.0014 0.0195
Trypanosoma brucei inositol-1(or 4)-monophosphatase 1, putative 0.0036 0.0018 0.0024
Loa Loa (eye worm) hypothetical protein 0.0109 0.0111 0.011
Onchocerca volvulus 0.0047 0.0032 0.0096
Trypanosoma brucei DNA topoisomerase IB, large subunit 0.5969 0.7481 1
Echinococcus multilocularis Ribosomal protein S1, RNA binding domain 0.0053 0.0041 0.004
Brugia malayi follicle stimulating hormone receptor 0.0566 0.0685 0.0685
Echinococcus multilocularis nmda type glutamate receptor 0.0131 0.0138 0.0138
Brugia malayi Pre-SET motif family protein 0.0205 0.0232 0.0232
Schistosoma mansoni chimerin-related rho-gtpase-activating protein 0.0212 0.024 0.024
Onchocerca volvulus 0.0027 0.0007 0.002
Trichomonas vaginalis penicillin-binding protein, putative 0.0035 0.0017 0.0585
Echinococcus multilocularis beta LACTamase domain containing family member 0.0035 0.0017 0.0017
Echinococcus multilocularis dro:myosuppressin receptor 0.0109 0.0111 0.011
Loa Loa (eye worm) hypothetical protein 0.0023 0.0002 0.0002
Trypanosoma cruzi PAB1-binding protein , putative 0.0026 0.0006 0.0007
Brugia malayi Glutamate receptor 1 precursor 0.0144 0.0155 0.0155
Echinococcus granulosus Glutamate receptor ionotropic kainate 2 0.0159 0.0174 0.0173
Leishmania major hypothetical protein, conserved 0.0026 0.0006 0.0007
Leishmania major tyrosyl-DNA phosphodiesterase 1 0.0067 0.0058 0.0077
Schistosoma mansoni hypothetical protein 0.0996 0.1226 0.1226
Echinococcus multilocularis N chimaerin 0.0212 0.024 0.024
Brugia malayi Cytochrome P450 family protein 0.0037 0.002 0.002
Brugia malayi glutamate-gated chloride channel alpha3A subunit, putative 0.0023 0.0002 0.0002
Loa Loa (eye worm) hypothetical protein 0.0109 0.0111 0.011
Loa Loa (eye worm) hypothetical protein 0.005 0.0036 0.0036
Loa Loa (eye worm) hypothetical protein 0.0109 0.0111 0.011
Onchocerca volvulus 0.005 0.0036 0.0107
Schistosoma mansoni biogenic amine receptor 0.0109 0.0111 0.011
Onchocerca volvulus 0.0109 0.0111 0.0333
Plasmodium falciparum ATP-dependent 6-phosphofructokinase 0.003 0.0011 0.0011
Schistosoma mansoni sodium/chloride dependent transporter 0.0097 0.0096 0.0095
Loa Loa (eye worm) unidentified vitellogenin-linked transcript protein 6 0.0109 0.0111 0.011
Echinococcus multilocularis fmrfamide receptor 0.0109 0.0111 0.011
Loa Loa (eye worm) hypothetical protein 0.0212 0.024 0.024
Echinococcus granulosus fmrfamide receptor 0.0109 0.0111 0.011
Brugia malayi beta-lactamase family protein 0.0035 0.0017 0.0017
Echinococcus granulosus rhodopsin orphan GPCR 0.0109 0.0111 0.011
Loa Loa (eye worm) hypothetical protein 0.0366 0.0433 0.0433
Trypanosoma cruzi Lanosterol 14-alpha demethylase 0.0028 0.0009 0.0011
Schistosoma mansoni amine GPCR 0.0109 0.0111 0.011
Brugia malayi Hypothetical 52.5 kDa protein ZK945.1 in chromosome II, putative 0.0035 0.0017 0.0017
Loa Loa (eye worm) hypothetical protein 0.0031 0.0013 0.0013
Schistosoma mansoni muscarinic acetylcholine (GAR) receptor 0.0109 0.0111 0.011
Brugia malayi Cation transporter family protein 0.012 0.0125 0.0125
Mycobacterium ulcerans exodeoxyribonuclease III protein XthA 0.0056 0.0044 0.336
Loa Loa (eye worm) 6-phosphofructokinase 0.011 0.0112 0.0112
Brugia malayi p70 ribosomal S6 kinase beta 0.0237 0.0272 0.0272
Loa Loa (eye worm) hypothetical protein 0.005 0.0036 0.0036
Echinococcus granulosus neuropeptides capa receptor 0.0109 0.0111 0.011
Loa Loa (eye worm) hypothetical protein 0.0027 0.0007 0.0007
Mycobacterium tuberculosis Probable oxidoreductase 0.0118 0.0122 0.4642
Trichomonas vaginalis AGC family protein kinase 0.025 0.0287 1
Brugia malayi Neurotransmitter-gated ion-channel transmembrane region family protein 0.005 0.0036 0.0036
Loa Loa (eye worm) hypothetical protein 0.0023 0.0002 0.0002
Loa Loa (eye worm) hypothetical protein 0.0109 0.0111 0.011
Loa Loa (eye worm) hypothetical protein 0.0109 0.0111 0.011
Leishmania major C-14 sterol reductase, putative 0.0093 0.0091 0.0121
Trypanosoma brucei C-8 sterol isomerase, putative 0.3974 0.4972 0.6646
Loa Loa (eye worm) hypothetical protein 0.0109 0.0111 0.011
Schistosoma mansoni norepinephrine/norepinephrine transporter 0.0535 0.0647 0.0646
Loa Loa (eye worm) hypothetical protein 0.0109 0.0111 0.011
Echinococcus granulosus raf serine:threonine protein kinase 0.0212 0.024 0.024
Loa Loa (eye worm) hypothetical protein 0.0026 0.0006 0.0005
Loa Loa (eye worm) nicotinic acetylcholine receptor non-alpha subunit 0.005 0.0036 0.0036
Schistosoma mansoni rac gtpase activating protein 0.0212 0.024 0.024
Brugia malayi Neurotransmitter-gated ion-channel ligand binding domain containing protein 0.0023 0.0002 0.0002
Schistosoma mansoni serine/threonine kinase 0.0237 0.0272 0.0271
Trypanosoma cruzi C2 domain/Ankyrin repeats (3 copies), putative 0.0021 0 0.0000000034972
Loa Loa (eye worm) hypothetical protein 0.1066 0.1314 0.1314
Leishmania major protein kinase, putative 0.0024 0.0004 0.0004
Loa Loa (eye worm) excitatory GABA receptor EXP-1A 0.005 0.0036 0.0036
Echinococcus multilocularis thyrotropin releasing hormone receptor 0.0109 0.0111 0.011
Brugia malayi hypothetical protein 0.0109 0.0111 0.0111
Echinococcus multilocularis ribosomal protein s6 kinase beta 1 0.0237 0.0272 0.0271
Loa Loa (eye worm) neuronal acetylcholine receptor protein 0.0023 0.0002 0.0002
Trypanosoma brucei DNA topoisomerase type IB small subunit 0.2003 0.2493 0.3332
Brugia malayi nicotinic acetylcholine receptor alpha subunit, putative 0.005 0.0036 0.0036
Loa Loa (eye worm) hypothetical protein 0.005 0.0036 0.0036
Echinococcus multilocularis Glutamate receptor, ionotropic kainate 2 0.0159 0.0174 0.0173
Echinococcus granulosus tar DNA binding protein 0.0062 0.0052 0.0051
Schistosoma mansoni nAChR subunit 0.005 0.0036 0.0036
Onchocerca volvulus 0.0027 0.0007 0.002
Brugia malayi hypothetical protein 0.0023 0.0002 0.0002
Brugia malayi Neurotransmitter-gated ion-channel ligand binding domain containing protein 0.005 0.0036 0.0036
Echinococcus multilocularis cadherin EGF LAG seven pass G type receptor 0.0031 0.0013 0.0013
Loa Loa (eye worm) exodeoxyribonuclease III family protein 0.0056 0.0044 0.0043
Onchocerca volvulus 0.0535 0.0647 0.1947
Loa Loa (eye worm) inositol-1 0.0036 0.0018 0.0018
Loa Loa (eye worm) hypothetical protein 0.0109 0.0111 0.011
Loa Loa (eye worm) hypothetical protein 0.0109 0.0111 0.011
Entamoeba histolytica protein kinase, putative 0.0028 0.0009 0.0157
Brugia malayi hypothetical protein 0.0109 0.0111 0.0111
Schistosoma mansoni biogenic amine (5HT) receptor 0.0109 0.0111 0.011
Brugia malayi 6-phosphofructokinase 0.011 0.0112 0.0112
Schistosoma mansoni glutamate receptor NMDA 0.0307 0.0359 0.0359
Echinococcus multilocularis glutamate receptor 2 0.0144 0.0155 0.0155
Loa Loa (eye worm) variant SH3 domain-containing protein 0.0034 0.0016 0.0015
Echinococcus granulosus tm gpcr rhodopsin 0.276 0.3445 0.3445
Loa Loa (eye worm) hypothetical protein 0.0109 0.0111 0.011
Echinococcus multilocularis bloom syndrome protein 0.0042 0.0026 0.0026
Schistosoma mansoni sodium/chloride dependent neurotransmitter transporter 0.0091 0.0088 0.0087
Schistosoma mansoni neuropeptide F-like receptor 0.0109 0.0111 0.011
Schistosoma mansoni hypothetical protein 0.0109 0.0111 0.011
Loa Loa (eye worm) hypothetical protein 0.0027 0.0007 0.0007
Schistosoma mansoni opsin-like receptor 0.0109 0.0111 0.011
Brugia malayi Inositol-1 0.0036 0.0018 0.0018
Onchocerca volvulus 0.012 0.0125 0.0374
Echinococcus multilocularis glutamate receptor, ionotrophic, AMPA 3 0.0159 0.0174 0.0173
Loa Loa (eye worm) AGC/RSK/MSK protein kinase 0.0237 0.0272 0.0271
Echinococcus granulosus somatostatin receptor 0.0109 0.0111 0.011
Brugia malayi glutathione reductase 0.0047 0.0032 0.0032
Trichomonas vaginalis AGC family protein kinase 0.025 0.0287 1
Schistosoma mansoni nicotinic acetylcholine receptor alpha 0.0027 0.0007 0.0007
Trichomonas vaginalis phosphofructokinase, putative 0.011 0.0112 0.3901
Brugia malayi hypothetical protein 0.0229 0.0262 0.0262
Trichomonas vaginalis D-aminoacylase, putative 0.0035 0.0017 0.0585
Loa Loa (eye worm) hypothetical protein 0.0023 0.0002 0.0002
Echinococcus granulosus serotonin receptor 0.0109 0.0111 0.011
Loa Loa (eye worm) TYRA-2 protein 0.0109 0.0111 0.011
Loa Loa (eye worm) hypothetical protein 0.0091 0.0088 0.0087
Schistosoma mansoni sodium-dependent amino acid transporter 0.0091 0.0088 0.0087
Trypanosoma cruzi hypothetical protein, conserved 0.0035 0.0017 0.0022
Loa Loa (eye worm) hypothetical protein 0.0109 0.0111 0.011
Loa Loa (eye worm) hypothetical protein 0.0109 0.0111 0.011
Echinococcus multilocularis Diacylglycerol kinase theta 0.0212 0.024 0.024
Echinococcus granulosus nAChR subunit 0.005 0.0036 0.0036
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0109 0.0111 0.011
Schistosoma mansoni cytochrome P450 0.0028 0.0009 0.0008
Schistosoma mansoni amine GPCR 0.0109 0.0111 0.011
Trichomonas vaginalis glucosylceramidase, putative 0.0164 0.0179 0.6236
Echinococcus granulosus Glutamate receptor ionotropic kainate 2 0.0159 0.0174 0.0173
Echinococcus multilocularis acetylcholine receptor subunit beta 1 0.005 0.0036 0.0036
Loa Loa (eye worm) hypothetical protein 0.0109 0.0111 0.011
Schistosoma mansoni peptide (FMRFamide/somatostatin)-like receptor 0.0109 0.0111 0.011
Schistosoma mansoni histone-lysine n-methyltransferase setb1 0.0029 0.0011 0.001
Trypanosoma brucei PAB1-binding protein , putative 0.0026 0.0006 0.0007
Entamoeba histolytica PH domain containing protein kinase, putative 0.0433 0.0518 1
Brugia malayi Neurotransmitter-gated ion-channel ligand binding domain containing protein 0.0023 0.0002 0.0002
Schistosoma mansoni 6-phosphofructokinase 0.011 0.0112 0.0112
Brugia malayi Corticotropin releasing factor receptor 2 precursor, putative 0.0099 0.0098 0.0098
Loa Loa (eye worm) follicle stimulating hormone receptor 0.0566 0.0685 0.0685
Echinococcus multilocularis neuropeptide Y receptor 0.0109 0.0111 0.011
Brugia malayi TAR-binding protein 0.0062 0.0052 0.0052
Brugia malayi Voltage-gated potassium channel, HERG (KCNH2)-related. C. elegans unc-103 ortholog 0.0037 0.002 0.002
Schistosoma mansoni Cys-loop ligand gated ion channel subunit 0.005 0.0036 0.0036
Echinococcus granulosus glycine receptor subunit alpha 1 0.005 0.0036 0.0036
Leishmania major sterol C-24 reductase, putative 0.0048 0.0034 0.0045
Trypanosoma brucei rac serine-threonine kinase, putative 0.025 0.0287 0.0384
Brugia malayi hypothetical protein 0.0109 0.0111 0.0111
Echinococcus granulosus protein kinase c epsilon type 0.0885 0.1087 0.1087
Trichomonas vaginalis AGC family protein kinase 0.025 0.0287 1
Echinococcus granulosus lamin b receptor 0.0093 0.0091 0.009
Echinococcus multilocularis glutamate receptor 2 0.0159 0.0174 0.0173
Echinococcus granulosus thioredoxin glutathione reductase 0.0047 0.0032 0.0032
Loa Loa (eye worm) hypothetical protein 0.0023 0.0002 0.0002
Echinococcus multilocularis serine:threonine protein kinase 38 0.0237 0.0272 0.0271
Loa Loa (eye worm) 5-hydroxytryptamine 2C receptor 0.0109 0.0111 0.011
Trichomonas vaginalis AGC family protein kinase 0.025 0.0287 1
Trypanosoma brucei ATP-dependent 6-phosphofructokinase, glycosomal 0.011 0.0112 0.015
Echinococcus multilocularis glycine receptor subunit beta 0.005 0.0036 0.0036
Loa Loa (eye worm) hypothetical protein 0.0026 0.0007 0.0006
Trichomonas vaginalis AGC family protein kinase 0.025 0.0287 1
Echinococcus granulosus rhodopsin orphan GPCR 0.0109 0.0111 0.011
Brugia malayi Glutamate receptor 2 precursor 0.0144 0.0155 0.0155
Brugia malayi Cytochrome P450 family protein 0.0028 0.0009 0.0009
Echinococcus granulosus glutamate receptor ionotropic kainate 0.0053 0.0041 0.004
Onchocerca volvulus Glucosylceramidase homolog 0.0164 0.0179 0.0539
Echinococcus multilocularis serine:threonine protein kinase N2 0.0652 0.0793 0.0793
Brugia malayi Dopamine receptor protein 1 0.0109 0.0111 0.0111
Brugia malayi cytochrome P450 0.0028 0.0009 0.0009
Brugia malayi Sodium:neurotransmitter symporter family protein 0.0091 0.0088 0.0088
Loa Loa (eye worm) hypothetical protein 0.0091 0.0088 0.0087
Trichomonas vaginalis glucosylceramidase, putative 0.0249 0.0287 0.9997
Brugia malayi diacylglycerol kinase 0.0212 0.024 0.024
Loa Loa (eye worm) variant SH3 domain-containing protein 0.0212 0.024 0.024
Schistosoma mansoni amine GPCR 0.0109 0.0111 0.011
Loa Loa (eye worm) hypothetical protein 0.0578 0.07 0.07
Trichomonas vaginalis AGC family protein kinase 0.025 0.0287 1
Echinococcus granulosus cadherin EGF LAG seven pass G type receptor 0.0031 0.0013 0.0013
Mycobacterium leprae PROBABLE NADH DEHYDROGENASE NDH 0.0106 0.0107 0.8682
Mycobacterium tuberculosis Probable esterase LipL 0.0035 0.0017 0.0341
Echinococcus multilocularis nAChR subunit 0.0027 0.0007 0.0007
Echinococcus multilocularis sodium and chloride dependent glycine 0.0091 0.0088 0.0087
Brugia malayi excitatory GABA receptor EXP-1A 0.005 0.0036 0.0036
Brugia malayi hypothetical protein 0.0109 0.0111 0.0111
Loa Loa (eye worm) cytochrome P450 family protein 0.0037 0.002 0.002
Schistosoma mansoni ancient conserved domain protein 2 (cyclin m2) 0.0109 0.0111 0.011
Trichomonas vaginalis glucosylceramidase, putative 0.0249 0.0287 0.9997
Echinococcus multilocularis transcription factor Dp 1 0.0039 0.0022 0.0022
Leishmania major lanosterol 14-alpha-demethylase, putative 0.0028 0.0009 0.0011
Brugia malayi G protein-coupled receptor F59B2.13 0.0109 0.0111 0.0111
Schistosoma mansoni sodium-dependent neurotransmitter transporter 0.0091 0.0088 0.0087
Entamoeba histolytica tyrosyl-DNA phosphodiesterase, putative 0.0067 0.0058 0.1108
Echinococcus multilocularis neuropeptide receptor A26 0.0109 0.0111 0.011
Trichomonas vaginalis inositol monophosphatase, putative 0.0036 0.0018 0.0624
Leishmania major ATP-dependent DEAD/H DNA helicase recQ, putative 0.0022 0.0002 0.0002
Loa Loa (eye worm) hypothetical protein 0.0212 0.024 0.024
Loa Loa (eye worm) hypothetical protein 0.0109 0.0111 0.011
Plasmodium vivax thioredoxin reductase, putative 0.0047 0.0032 0.0032
Schistosoma mansoni neurotransmitter gated ion channel 0.0023 0.0002 0.0002
Loa Loa (eye worm) ACC-1 protein 0.005 0.0036 0.0036
Leishmania major trypanothione reductase 0.0047 0.0032 0.0042
Schistosoma mansoni vesicular amine transporter 0.019 0.0213 0.0212
Echinococcus multilocularis G protein coupled receptor 139 0.0109 0.0111 0.011
Loa Loa (eye worm) ACC-1 protein 0.005 0.0036 0.0036
Echinococcus multilocularis Glutamate receptor, ionotropic kainate 2 0.0159 0.0174 0.0173
Schistosoma mansoni tar DNA-binding protein 0.0062 0.0052 0.0051
Schistosoma mansoni hypothetical protein 0.0109 0.0111 0.011
Echinococcus multilocularis sodium dependent neurotransmitter transporter 0.0091 0.0088 0.0087
Plasmodium falciparum thioredoxin reductase 0.0047 0.0032 0.0032
Onchocerca volvulus 0.0091 0.0088 0.0263
Loa Loa (eye worm) tyrosyl-DNA phosphodiesterase 0.0067 0.0058 0.0057
Loa Loa (eye worm) hypothetical protein 0.005 0.0036 0.0036
Schistosoma mansoni norepinephrine/norepinephrine transporter 0.0091 0.0088 0.0087
Brugia malayi Sodium:neurotransmitter symporter family protein 0.0091 0.0088 0.0088
Trichomonas vaginalis ap endonuclease, putative 0.0056 0.0044 0.1506
Echinococcus granulosus myotubularin protein 13 0.0224 0.0256 0.0255
Schistosoma mansoni ATP-binding cassette transporter 0.0144 0.0155 0.0155
Loa Loa (eye worm) AGC/PKC/IOTA protein kinase 0.0484 0.0583 0.0582
Onchocerca volvulus 0.0109 0.0111 0.0333
Loa Loa (eye worm) hypothetical protein 0.0212 0.024 0.024
Echinococcus multilocularis nmda type glutamate receptor 0.0092 0.009 0.0089
Mycobacterium tuberculosis Probable 6-phosphofructokinase PfkA (phosphohexokinase) (phosphofructokinase) 0.011 0.0112 0.4239
Loa Loa (eye worm) RNA binding protein 0.0062 0.0052 0.0051
Schistosoma mansoni microtubule-associated protein tau 0.069 0.0841 0.0841
Mycobacterium tuberculosis Probable exodeoxyribonuclease III protein XthA (exonuclease III) (EXO III) (AP endonuclease VI) 0.0056 0.0044 0.1425
Trypanosoma cruzi ATP-dependent 6-phosphofructokinase, glycosomal 0.011 0.0112 0.015
Echinococcus granulosus protein kinase C gamma type 0.0695 0.0848 0.0848
Mycobacterium tuberculosis Possible conserved lipoprotein LpqK 0.0035 0.0017 0.0341
Mycobacterium ulcerans beta-lactamase 0.0035 0.0017 0.0805
Echinococcus granulosus glutamate receptor subunit protein glur 0.0053 0.0041 0.004
Loa Loa (eye worm) phosphofructokinase 0.011 0.0112 0.0112
Schistosoma mansoni nAChR subunit 0.0023 0.0002 0.0002
Echinococcus granulosus gamma aminobutyric acid receptor subunit 0.0023 0.0002 0.0002
Loa Loa (eye worm) raf kinase 0.0212 0.024 0.024
Plasmodium falciparum AP endonuclease (DNA-[apurinic or apyrimidinic site] lyase), putative 0.0056 0.0044 0.0043
Loa Loa (eye worm) hypothetical protein 0.2031 0.2528 0.2528
Toxoplasma gondii ABC1 family protein 0.0035 0.0017 0.0017
Echinococcus granulosus cytochrome P450 2K1 0.0028 0.0009 0.0008
Onchocerca volvulus 0.0109 0.0111 0.0333
Loa Loa (eye worm) glutamate receptor 2 0.0144 0.0155 0.0155
Loa Loa (eye worm) hypothetical protein 0.0023 0.0002 0.0002
Loa Loa (eye worm) hypothetical protein 0.0944 0.1161 0.116
Mycobacterium tuberculosis Probable NADH dehydrogenase Ndh 0.0106 0.0107 0.403
Echinococcus granulosus single minded 2 0.0039 0.0023 0.0022
Toxoplasma gondii Sodium:neurotransmitter symporter family protein 0.0091 0.0088 0.0087
Entamoeba histolytica phosphofructokinase, putative 0.011 0.0112 0.2161
Mycobacterium leprae possible inositol monophosphatase SubH (IMPase) (inositol-1-phosphatase) (I-1-Pase ). 0.0032 0.0014 0.042
Brugia malayi hypothetical protein 0.0109 0.0111 0.0111
Loa Loa (eye worm) hypothetical protein 0.0099 0.0098 0.0098
Brugia malayi Bloom's syndrome protein homolog 0.0042 0.0026 0.0026
Brugia malayi Dopamine receptor protein 1, putative (partial) 0.0109 0.0111 0.0111
Loa Loa (eye worm) G-protein coupled receptor 0.0109 0.0111 0.011
Echinococcus multilocularis glutamate receptor NMDA 0.0077 0.0071 0.007
Trypanosoma cruzi tyrosyl-DNA Phosphodiesterase (Tdp1), putative 0.0067 0.0058 0.0077
Loa Loa (eye worm) AGC/PKC/ETA protein kinase 0.0885 0.1087 0.1087
Trichomonas vaginalis glucosylceramidase, putative 0.0173 0.019 0.6622
Echinococcus multilocularis pyroglutamylated rfamide peptide receptor 0.0109 0.0111 0.011
Brugia malayi Protein kinase domain containing protein 0.0237 0.0272 0.0272
Brugia malayi Calcitonin receptor-like protein seb-1 0.0099 0.0098 0.0098
Brugia malayi Neurotransmitter-gated ion-channel transmembrane region family protein 0.005 0.0036 0.0036
Brugia malayi nicotinic acetylcholine receptor beta-1 chain precursor 0.005 0.0036 0.0036
Loa Loa (eye worm) melatonin receptor type 1A 0.0109 0.0111 0.011
Brugia malayi protein kinase C II. 0.0885 0.1087 0.1087
Echinococcus multilocularis g protein coupled receptor 0.0109 0.0111 0.011
Mycobacterium ulcerans 6-phosphofructokinase 0.011 0.0112 1
Toxoplasma gondii DNA topoisomerase I, putative 0.7972 1 1
Echinococcus multilocularis guanine nucleotide exchange factor VAV2 0.0212 0.024 0.024
Trichomonas vaginalis penicillin-binding protein, putative 0.0035 0.0017 0.0585
Leishmania major C-8 sterol isomerase-like protein 0.3974 0.4972 0.6646
Schistosoma mansoni nAChR subunit 0.005 0.0036 0.0036
Schistosoma mansoni survival motor neuron protein 0.0047 0.0032 0.0032
Onchocerca volvulus 0.0109 0.0111 0.0333
Brugia malayi Intermediate filament tail domain containing protein 0.0026 0.0007 0.0007
Loa Loa (eye worm) AGC/PKN protein kinase 0.0237 0.0272 0.0271
Brugia malayi diacylglycerol kinase 0.0212 0.024 0.024
Echinococcus granulosus guanine nucleotide binding protein Gs subunit 0.0046 0.0032 0.0031
Loa Loa (eye worm) neuropeptide F receptor 0.0109 0.0111 0.011
Echinococcus multilocularis histone lysine methyltransferase setb histone lysine methyltransferase eggless 0.0029 0.0011 0.001
Echinococcus multilocularis g-protein coupled receptor 0.0109 0.0111 0.011
Onchocerca volvulus 0.0366 0.0433 0.1304
Brugia malayi hypothetical protein 0.0023 0.0002 0.0002
Trypanosoma brucei trypanothione reductase 0.0047 0.0032 0.0042
Loa Loa (eye worm) hypothetical protein 0.0109 0.0111 0.011
Loa Loa (eye worm) hypothetical protein 0.0109 0.0111 0.011
Schistosoma mansoni acetylcholine receptor-related 0.0023 0.0002 0.0002
Schistosoma mansoni biogenic amine receptor 0.0109 0.0111 0.011
Brugia malayi gonadotropin-releasing hormone receptor 2 0.0109 0.0111 0.0111
Brugia malayi Sodium:neurotransmitter symporter family protein 0.0535 0.0647 0.0647
Brugia malayi Neurotransmitter-gated ion-channel transmembrane region family protein 0.0027 0.0007 0.0007
Loa Loa (eye worm) hypothetical protein 0.0109 0.0111 0.011
Loa Loa (eye worm) hypothetical protein 0.0163 0.0178 0.0178
Mycobacterium ulcerans fusion of enoyl-CoA hydratase, EchA21 and lipase, LipE 0.0035 0.0017 0.0805
Echinococcus multilocularis neuropeptides capa receptor 0.0109 0.0111 0.011
Schistosoma mansoni tar DNA-binding protein 0.0062 0.0052 0.0051
Loa Loa (eye worm) hypothetical protein 0.0109 0.0111 0.011
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0109 0.0111 0.011
Echinococcus multilocularis glycine receptor subunit alpha 1 0.005 0.0036 0.0036
Echinococcus granulosus peptide allatostatin:somatostatin 0.0109 0.0111 0.011
Trypanosoma brucei hypothetical protein, conserved 0.0035 0.0017 0.0022
Schistosoma mansoni ap endonuclease 0.0056 0.0044 0.0043
Schistosoma mansoni acetylcholine receptor subunit beta 0.0023 0.0002 0.0002
Loa Loa (eye worm) pigment dispersing factor receptor c 0.0099 0.0098 0.0098
Echinococcus granulosus glycine receptor subunit alpha 1 0.005 0.0036 0.0036
Loa Loa (eye worm) RecQ helicase 0.0042 0.0026 0.0026
Schistosoma mansoni hypothetical protein 0.0028 0.0009 0.0008
Brugia malayi GTP-binding regulatory protein Gs alpha-S chain, putative 0.0046 0.0032 0.0032
Brugia malayi RE15519p 0.0109 0.0111 0.0111
Echinococcus granulosus N chimaerin 0.0212 0.024 0.024
Echinococcus granulosus nmda type glutamate receptor 0.0092 0.009 0.0089
Echinococcus granulosus transcription factor Dp 1 0.0039 0.0022 0.0022
Onchocerca volvulus 0.0829 0.1016 0.3059
Loa Loa (eye worm) hypothetical protein 0.005 0.0036 0.0036
Echinococcus multilocularis Ribosomal protein S6 kinase beta 2 0.0237 0.0272 0.0271
Trichomonas vaginalis glucosylceramidase, putative 0.0249 0.0287 0.9997
Trypanosoma cruzi cytochrome P450, putative 0.0037 0.002 0.0026
Loa Loa (eye worm) hypothetical protein 0.005 0.0036 0.0036
Trichomonas vaginalis AGC family protein kinase 0.025 0.0287 1
Schistosoma mansoni tar DNA-binding protein 0.0062 0.0052 0.0051
Echinococcus multilocularis myotubularin protein 13 0.0224 0.0256 0.0255
Loa Loa (eye worm) hypothetical protein 0.0109 0.0111 0.011
Trichomonas vaginalis voltage and ligand gated potassium channel, putative 0.0034 0.0017 0.0571
Trichomonas vaginalis voltage and ligand gated potassium channel, putative 0.0034 0.0017 0.0571
Echinococcus granulosus g-protein coupled receptor 0.0109 0.0111 0.011
Echinococcus granulosus dro:myosuppressin receptor 0.0109 0.0111 0.011
Brugia malayi hypothetical protein 0.0163 0.0178 0.0178
Trypanosoma cruzi hypothetical protein, conserved 0.0035 0.0017 0.0022
Echinococcus multilocularis somatostatin receptor 0.0109 0.0111 0.011
Echinococcus multilocularis vesicular acetylcholine transporter 0.2661 0.332 0.332
Echinococcus granulosus Diacylglycerol kinase theta 0.0212 0.024 0.024
Brugia malayi Variant SH3 domain containing protein 0.0212 0.024 0.024
Loa Loa (eye worm) RhoGAP domain-containing protein 0.0212 0.024 0.024
Brugia malayi ERG2 and Sigma1 receptor like protein 0.3974 0.4972 0.4972
Trichomonas vaginalis esterase, putative 0.0035 0.0017 0.0585
Brugia malayi latrophilin 2 splice variant baaae 0.0068 0.0059 0.0059
Echinococcus granulosus beta LACTamase domain containing family member 0.0035 0.0017 0.0017
Mycobacterium tuberculosis NADPH-dependent mycothiol reductase Mtr 0.0047 0.0032 0.0952
Plasmodium vivax ataxin-2 like protein, putative 0.0026 0.0006 0.0005
Trypanosoma cruzi apurinic/apyrimidinic endonuclease, putative 0.0056 0.0044 0.0058
Schistosoma mansoni nAChR subunit 0.005 0.0036 0.0036
Brugia malayi RNA binding protein 0.0062 0.0052 0.0052
Echinococcus granulosus sex peptide receptor 0.0109 0.0111 0.011
Echinococcus granulosus RNA directed DNA polymerase 0.0437 0.0523 0.0522
Echinococcus granulosus tm gpcr rhodopsin 0.0109 0.0111 0.011
Brugia malayi Dopamine receptor 0.0109 0.0111 0.0111
Toxoplasma gondii exonuclease III APE 0.0056 0.0044 0.0043
Loa Loa (eye worm) AGC/AKT protein kinase 0.025 0.0287 0.0287
Loa Loa (eye worm) hypothetical protein 0.0944 0.1161 0.116
Schistosoma mansoni protein kinase C mu 0.0584 0.0708 0.0708
Loa Loa (eye worm) hypothetical protein 0.0109 0.0111 0.011
Schistosoma mansoni neurotransmitter gated ion channel 0.0027 0.0007 0.0007
Onchocerca volvulus 0.0109 0.0111 0.0333
Echinococcus granulosus histone lysine methyltransferase setb 0.0029 0.0011 0.001
Onchocerca volvulus 0.0023 0.0002 0.0006
Schistosoma mansoni myosin xvIII 0.0109 0.0111 0.011
Loa Loa (eye worm) glutamate-gated chloride channel alpha3A subunit 0.0023 0.0002 0.0002
Brugia malayi Melatonin receptor type 1A 0.0109 0.0111 0.0111
Echinococcus multilocularis unc 13 (munc13) 0.0234 0.0267 0.0267
Echinococcus multilocularis tm gpcr rhodopsin gpcr rhodopsin superfamily 0.0109 0.0111 0.011
Loa Loa (eye worm) hypothetical protein 0.0109 0.0111 0.011
Schistosoma mansoni family S12 unassigned peptidase (S12 family) 0.0035 0.0017 0.0017
Loa Loa (eye worm) beta-lactamase 0.0035 0.0017 0.0017
Onchocerca volvulus 0.0091 0.0088 0.0263
Brugia malayi calcium-independent alpha-latrotoxin receptor 2, putative 0.0031 0.0013 0.0013
Brugia malayi Protein kinase domain containing protein 0.0237 0.0272 0.0272
Entamoeba histolytica hypothetical protein 0.0212 0.024 0.4631
Brugia malayi hypothetical protein 0.0109 0.0111 0.0111
Schistosoma mansoni protein kinase C mu 0.0212 0.024 0.024
Loa Loa (eye worm) hypothetical protein 0.005 0.0036 0.0036
Loa Loa (eye worm) hypothetical protein 0.0109 0.0111 0.011
Echinococcus granulosus rhodopsin orphan GPCR 0.0109 0.0111 0.011
Schistosoma mansoni serine/threonine protein kinase 0.0237 0.0272 0.0271
Echinococcus granulosus orexin receptor type 2 0.0109 0.0111 0.011
Mycobacterium tuberculosis NAD(P)H quinone reductase LpdA 0.0118 0.0122 0.4642
Onchocerca volvulus 0.0109 0.0111 0.0333
Leishmania major hypothetical protein, conserved 0.0026 0.0007 0.0008
Loa Loa (eye worm) hypothetical protein 0.0109 0.0111 0.011
Loa Loa (eye worm) hypothetical protein 0.0109 0.0111 0.011
Loa Loa (eye worm) gonadotropin-releasing hormone receptor 2 0.0109 0.0111 0.011
Brugia malayi neuropeptide F receptor 0.0109 0.0111 0.0111
Toxoplasma gondii phosphofructokinase PFKII 0.003 0.0011 0.0011
Echinococcus multilocularis raf serine:threonine protein kinase 0.0212 0.024 0.024
Treponema pallidum diphosphate--fructose-6-phosphate 1-phosphotransferase 0.011 0.0112 0.1594
Schistosoma mansoni serine/threonine protein kinase 0.0219 0.0248 0.0248
Schistosoma mansoni amine GPCR 0.0109 0.0111 0.011
Toxoplasma gondii inositol(myo)-1(or 4)-monophosphatase 2, putative 0.0036 0.0018 0.0018
Echinococcus multilocularis neuropeptide receptor 0.0109 0.0111 0.011
Schistosoma mansoni amine GPCR 0.0109 0.0111 0.011
Schistosoma mansoni Cys-loop ligand gated ion channel subunit 0.005 0.0036 0.0036
Echinococcus granulosus nAChR subunit 0.0027 0.0007 0.0007
Schistosoma mansoni serine/threonine protein kinase 0.0907 0.1115 0.1114
Echinococcus granulosus Protein kinase C brain isozyme 0.0907 0.1115 0.1114
Loa Loa (eye worm) hypothetical protein 0.0023 0.0002 0.0002
Trichomonas vaginalis DNA helicase recq, putative 0.0042 0.0026 0.0903
Schistosoma mansoni nAChR subunit 0.0023 0.0002 0.0002
Echinococcus granulosus glutamate receptor NMDA 0.0077 0.0071 0.007
Brugia malayi RhoGEF domain containing protein 0.0212 0.024 0.024
Brugia malayi hypothetical protein 0.0091 0.0088 0.0088
Brugia malayi AKH receptor 0.0109 0.0111 0.0111
Echinococcus multilocularis Protein kinase C, brain isozyme 0.0907 0.1115 0.1114
Loa Loa (eye worm) vesicular acetylcholine transporter unc-17 0.2661 0.332 0.332
Toxoplasma gondii 6-phosphofructokinase 0.003 0.0011 0.0011
Loa Loa (eye worm) hypothetical protein 0.0035 0.0017 0.0017
Brugia malayi Abnormal catecholamine distribution protein 1 0.019 0.0213 0.0213
Echinococcus multilocularis glycine receptor subunit beta 0.005 0.0036 0.0036
Entamoeba histolytica myo-inositol monophosphatase, putative 0.0036 0.0018 0.0346
Schistosoma mansoni lipoxygenase 0.012 0.0124 0.0124
Echinococcus multilocularis tar DNA binding protein 0.0062 0.0052 0.0051
Trichomonas vaginalis phosphofructokinase, putative 0.011 0.0112 0.3901
Trichomonas vaginalis glucosylceramidase, putative 0.0164 0.0179 0.6236
Loa Loa (eye worm) 6-phosphofructokinase 0.011 0.0112 0.0112
Brugia malayi hypothetical protein 0.0109 0.0111 0.0111
Loa Loa (eye worm) hypothetical protein 0.0109 0.0111 0.011
Trichomonas vaginalis glucosylceramidase, putative 0.0164 0.0179 0.6236
Echinococcus multilocularis ribosomal protein S6 kinase alpha 3 0.0237 0.0272 0.0271
Schistosoma mansoni tar DNA-binding protein 0.0062 0.0052 0.0051
Loa Loa (eye worm) hypothetical protein 0.0535 0.0647 0.0646
Trichomonas vaginalis ankyrin repeat-containing protein, putative 0.0021 0 0.000000091176
Trichomonas vaginalis phosphofructokinase, putative 0.011 0.0112 0.3901
Mycobacterium leprae Probable lipase LipE 0.0035 0.0017 0.0735
Mycobacterium leprae conserved hypothetical protein 0.0035 0.0017 0.0735
Loa Loa (eye worm) hypothetical protein 0.0109 0.0111 0.011
Brugia malayi glutamate-gated chloride channel alpha3A subunit, putative 0.0027 0.0007 0.0007
Loa Loa (eye worm) AGC/NDR protein kinase 0.0237 0.0272 0.0271
Schistosoma mansoni Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) 0.0046 0.0032 0.0031
Loa Loa (eye worm) intermediate filament tail domain-containing protein 0.0026 0.0007 0.0006
Onchocerca volvulus Putative nachr subunit 0.005 0.0036 0.0107
Loa Loa (eye worm) glutathione reductase 0.0047 0.0032 0.0032
Trypanosoma cruzi C-14 sterol reductase, putative 0.0093 0.0091 0.0121
Loa Loa (eye worm) hypothetical protein 0.0023 0.0002 0.0002
Toxoplasma gondii phosphofructokinase domain-containing protein 0.003 0.0011 0.0011
Echinococcus multilocularis lamin b receptor 0.0093 0.0091 0.009
Echinococcus granulosus nuclear factor of activated T cells 5 0.0075 0.0068 0.0067
Schistosoma mansoni inositol monophosphatase 0.0036 0.0018 0.0018
Mycobacterium tuberculosis Conserved protein 0.0035 0.0017 0.0341
Echinococcus multilocularis sex peptide receptor 0.0109 0.0111 0.011
Loa Loa (eye worm) hypothetical protein 0.0023 0.0002 0.0002
Trypanosoma cruzi myo-inositol-1(or 4)-monophosphatase 1, putative 0.0036 0.0018 0.0024
Schistosoma mansoni histone-lysine n-methyltransferase suv9 0.0029 0.0011 0.001
Echinococcus granulosus nicotinic acetylcholine receptor subunit alpha 8 0.005 0.0036 0.0036
Schistosoma mansoni single-minded 0.0048 0.0034 0.0034
Echinococcus multilocularis tm gpcr rhodopsin gpcr rhodopsin superfamily 0.276 0.3445 0.3445
Trichomonas vaginalis ion channel nompc, putative 0.0021 0 0.000000091176
Trypanosoma cruzi cAMP binding protein, putative 0.0026 0.0007 0.0008
Loa Loa (eye worm) G-protein coupled receptor 0.0109 0.0111 0.011
Onchocerca volvulus 0.0234 0.0267 0.0804
Onchocerca volvulus 0.0025 0.0004 0.0012
Brugia malayi G-protein-linked acetylcholine receptor protein 2, putative 0.0109 0.0111 0.0111
Loa Loa (eye worm) hypothetical protein 0.0023 0.0002 0.0002
Onchocerca volvulus 0.0109 0.0111 0.0333
Entamoeba histolytica diacylglycerol kinase, putative 0.0212 0.024 0.4631
Brugia malayi Ras association domain family 1 isoform A 0.0212 0.024 0.024
Schistosoma mansoni glutamate receptor kainate 0.0144 0.0155 0.0155
Loa Loa (eye worm) cytochrome P450 family protein 0.0028 0.0009 0.0008
Toxoplasma gondii diacylglycerol kinase, putative 0.0212 0.024 0.024
Schistosoma mansoni voltage-gated potassium channel 0.004 0.0024 0.0024
Mycobacterium tuberculosis Dihydrolipoamide dehydrogenase LpdC (lipoamide reductase (NADH)) (lipoyl dehydrogenase) (dihydrolipoyl dehydrogenase) (diaphoras 0.0118 0.0122 0.4642
Echinococcus multilocularis nicotinic acetylcholine receptor a11 subunit 0.005 0.0036 0.0036
Echinococcus granulosus glycine receptor subunit alpha 1 0.005 0.0036 0.0036
Plasmodium falciparum ataxin-2 like protein, putative 0.0026 0.0006 0.0005
Echinococcus granulosus glutamate receptor 2 0.0159 0.0174 0.0173
Echinococcus granulosus guanine nucleotide exchange factor VAV2 0.0212 0.024 0.024
Trypanosoma cruzi C-14 sterol reductase, putative 0.0093 0.0091 0.0121
Schistosoma mansoni histamine-responsive GPCR (AAF21638) 0.0109 0.0111 0.011
Onchocerca volvulus 0.0036 0.0019 0.0055
Echinococcus granulosus inositol monophosphatase 1 0.0036 0.0018 0.0018
Loa Loa (eye worm) hypothetical protein 0.0091 0.0088 0.0087
Brugia malayi exodeoxyribonuclease III family protein 0.0056 0.0044 0.0044
Trichomonas vaginalis phosphofructokinase, putative 0.003 0.0011 0.0368
Schistosoma mansoni vav2 0.0224 0.0256 0.0255
Trichomonas vaginalis D-aminoacylase, putative 0.0035 0.0017 0.0585
Echinococcus multilocularis Rac GTPase activating protein 1 0.0212 0.024 0.024
Toxoplasma gondii AGC kinase 0.0237 0.0272 0.0271
Trichomonas vaginalis phosphofructokinase, putative 0.003 0.0011 0.0368
Echinococcus granulosus sodium and chloride dependent glycine 0.0091 0.0088 0.0087
Schistosoma mansoni family S12 unassigned peptidase (S12 family) 0.0035 0.0017 0.0017
Loa Loa (eye worm) TAR-binding protein 0.0062 0.0052 0.0051
Echinococcus multilocularis 6 phosphofructokinase 0.011 0.0112 0.0112
Treponema pallidum exodeoxyribonuclease (exoA) 0.0056 0.0044 0.0514
Echinococcus granulosus 7TM GPCR rhodopsin 0.0109 0.0111 0.011
Loa Loa (eye worm) hypothetical protein 0.0027 0.0007 0.0007
Echinococcus multilocularis tachykinin peptides receptor 99D 0.0109 0.0111 0.011
Echinococcus granulosus tyrosyl DNA phosphodiesterase 1 0.0067 0.0058 0.0057
Echinococcus multilocularis sodium and chloride dependent glycine 0.0091 0.0088 0.0087
Brugia malayi putative neuropeptide receptor NPR1 0.0109 0.0111 0.0111
Mycobacterium tuberculosis Conserved protein 0.0035 0.0017 0.0341
Echinococcus multilocularis geminin 0.0996 0.1226 0.1226
Schistosoma mansoni atypical protein kinase C 0.0715 0.0873 0.0873
Schistosoma mansoni neuropeptide F-like receptor 0.0109 0.0111 0.011
Schistosoma mansoni DNA topoisomerase type I 0.5969 0.7481 0.7481
Echinococcus multilocularis g protein linked acetylcholine receptor gar 2a 0.0109 0.0111 0.011
Loa Loa (eye worm) hypothetical protein 0.0027 0.0007 0.0007
Echinococcus granulosus C2 calcium dependent membrane targeting 0.0234 0.0267 0.0267
Brugia malayi Hypothetical glycine receptor like protein T20B12.9 in chromosome III 0.005 0.0036 0.0036
Schistosoma mansoni intracisternal A-particle retropepsin (A02 family) 0.1528 0.1895 0.1895
Trypanosoma cruzi myo-inositol-1(or 4)-monophosphatase 1, putative 0.0036 0.0018 0.0024
Echinococcus granulosus neuropeptide s receptor 0.0109 0.0111 0.011
Leishmania major DNA topoisomerase IB, large subunit 0.5969 0.7481 1
Brugia malayi hypothetical protein 0.0023 0.0002 0.0002
Schistosoma mansoni diacylglycerol kinase theta 0.0212 0.024 0.024
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0109 0.0111 0.011
Echinococcus multilocularis neuropeptide FF receptor 2 0.0109 0.0111 0.011
Brugia malayi intermediate filament protein 0.0026 0.0007 0.0007
Brugia malayi Protein kinase domain containing protein 0.0025 0.0004 0.0004
Echinococcus multilocularis fmrfamide receptor 0.0109 0.0111 0.011
Loa Loa (eye worm) hypothetical protein 0.0034 0.0016 0.0015
Echinococcus multilocularis neuronal acetylcholine receptor subunit alpha 4 0.005 0.0036 0.0036
Echinococcus multilocularis Cys loop ligand gated ion channel subunit 0.0023 0.0002 0.0002
Echinococcus multilocularis guanine nucleotide binding protein G(s) subunit 0.0046 0.0032 0.0031
Brugia malayi PAS domain containing protein 0.0048 0.0034 0.0034
Loa Loa (eye worm) hypothetical protein 0.0109 0.0111 0.011
Schistosoma mansoni neuropeptide receptor 0.0109 0.0111 0.011
Plasmodium falciparum ataxin-2 like protein, putative 0.0026 0.0006 0.0005
Brugia malayi Sodium:neurotransmitter symporter family protein 0.0091 0.0088 0.0088
Loa Loa (eye worm) hypothetical protein 0.0109 0.0111 0.011
Onchocerca volvulus 0.0023 0.0002 0.0006
Trypanosoma brucei C-14 sterol reductase, putative 0.0093 0.0091 0.0121
Trichomonas vaginalis serine/threonine-protein kinase sgk, putative 0.0231 0.0264 0.9176
Echinococcus granulosus sodium:chloride dependent neurotransmitter 0.0091 0.0088 0.0087
Loa Loa (eye worm) Sodium:neurotransmitter symporter family protein 0.0091 0.0088 0.0087
Toxoplasma gondii Sodium:neurotransmitter symporter family protein 0.0091 0.0088 0.0087
Echinococcus granulosus Ribosomal protein S6 kinase beta 2 0.0237 0.0272 0.0271
Loa Loa (eye worm) hypothetical protein 0.0029 0.0011 0.001
Echinococcus multilocularis serine threonine protein kinase 0.0695 0.0848 0.0848
Schistosoma mansoni hypothetical protein 0.0996 0.1226 0.1226
Trichomonas vaginalis phosphofructokinase, putative 0.003 0.0011 0.0368
Schistosoma mansoni Cys-loop ligand gated ion channel subunit 0.0027 0.0007 0.0007
Brugia malayi Neurotransmitter-gated ion-channel ligand binding domain containing protein 0.005 0.0036 0.0036
Trypanosoma cruzi apurinic/apyrimidinic endonuclease 0.0056 0.0044 0.0058
Loa Loa (eye worm) RasGEF domain-containing protein 0.0212 0.024 0.024
Schistosoma mansoni DNA topoisomerase type I 0.5969 0.7481 0.7481
Mycobacterium tuberculosis Probable conserved lipoprotein 0.0035 0.0017 0.0341
Entamoeba histolytica protein kinase, putative 0.025 0.0287 0.554
Loa Loa (eye worm) hypothetical protein 0.0109 0.0111 0.011
Leishmania major cytochrome p450-like protein 0.0028 0.0009 0.0011
Echinococcus granulosus g protein coupled receptor 0.0109 0.0111 0.011
Schistosoma mansoni nAChR subunit 0.005 0.0036 0.0036
Trypanosoma brucei apurinic/apyrimidinic endonuclease, putative 0.0056 0.0044 0.0058
Schistosoma mansoni tyrosyl-DNA phosphodiesterase 0.0067 0.0058 0.0057
Loa Loa (eye worm) latrophilin receptor protein 2 0.0031 0.0013 0.0013
Entamoeba histolytica protein kinase, putative 0.0237 0.0272 0.524
Echinococcus granulosus uncharacterized sodium dependent transporter 0.0091 0.0088 0.0087
Wolbachia endosymbiont of Brugia malayi exonuclease III 0.0056 0.0044 1
Schistosoma mansoni sodium-dependent neurotransmitter transporter 0.0091 0.0088 0.0087
Echinococcus granulosus neuropeptide Y receptor 0.0109 0.0111 0.011
Echinococcus granulosus nicotinic acetylcholine receptor beta 1 subunit 0.005 0.0036 0.0036
Trichomonas vaginalis AGC family protein kinase 0.0237 0.0272 0.946
Brugia malayi Neurotransmitter-gated ion-channel ligand binding domain containing protein 0.005 0.0036 0.0036
Echinococcus granulosus rhodopsin orphan GPCR 0.0109 0.0111 0.011
Loa Loa (eye worm) hypothetical protein 0.0023 0.0002 0.0002
Mycobacterium tuberculosis Putative ferredoxin reductase 0.0106 0.0107 0.403
Trichomonas vaginalis myo inositol monophosphatase, putative 0.0036 0.0018 0.0624
Loa Loa (eye worm) CYP4Cod1 0.0037 0.002 0.002
Echinococcus multilocularis serotonin transporter 0.0535 0.0647 0.0646
Schistosoma mansoni hypothetical protein 0.0031 0.0013 0.0013
Trypanosoma brucei Lanosterol 14-alpha demethylase 0.0028 0.0009 0.0011
Echinococcus granulosus geminin 0.0996 0.1226 0.1226
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0109 0.0111 0.011
Trypanosoma cruzi cytochrome P450, putative 0.0037 0.002 0.0026
Trypanosoma cruzi DNA topoisomerase IB, large subunit, putative 0.5969 0.7481 1
Trichomonas vaginalis glucosylceramidase, putative 0.0249 0.0287 0.9997
Echinococcus multilocularis g protein coupled receptor 0.0109 0.0111 0.011
Loa Loa (eye worm) hypothetical protein 0.0109 0.0111 0.011
Echinococcus multilocularis glutamate receptor subunit protein glur 0.0053 0.0041 0.004
Loa Loa (eye worm) Ras association domain family 1 isoform A 0.0212 0.024 0.024
Schistosoma mansoni unc-13 (munc13) 0.0236 0.027 0.0269
Leishmania major DNA topoisomerase type IB small subunit 0.2003 0.2493 0.3332
Echinococcus multilocularis protein kinase c iota type 0.0697 0.085 0.085
Echinococcus granulosus growth hormone secretagogue receptor type 1 0.0109 0.0111 0.011
Trichomonas vaginalis myo inositol monophosphatase, putative 0.0036 0.0018 0.0624
Trypanosoma cruzi sterol C-24 reductase, putative 0.0048 0.0034 0.0045
Schistosoma mansoni hypothetical protein 0.0031 0.0013 0.0013
Toxoplasma gondii cytochrome p450 superfamily protein 0.0028 0.0009 0.0008
Echinococcus multilocularis DNA (apurinic or apyrimidinic site) lyase 0.0056 0.0044 0.0043
Leishmania major myo-inositol-1(or 4)-monophosphatase 1, putative 0.0036 0.0018 0.0024
Trichomonas vaginalis AGC family protein kinase 0.0237 0.0272 0.946
Echinococcus granulosus Serine/threonine-protein kinase Genghis Khan 0.0219 0.0248 0.0248
Echinococcus multilocularis RNA directed DNA polymerase 0.0437 0.0523 0.0522
Loa Loa (eye worm) hypothetical protein 0.0109 0.0111 0.011
Echinococcus granulosus nicotinic acetylcholine receptor subunit type 0.005 0.0036 0.0036
Echinococcus multilocularis guanine nucleotide binding protein G(s) subunit 0.0046 0.0032 0.0031
Onchocerca volvulus 0.0109 0.0111 0.0333
Chlamydia trachomatis Ssodium-dependent amino acid transporter 0.0091 0.0088 1
Brugia malayi ORL1-like opioid receptor 0.0109 0.0111 0.0111
Trichomonas vaginalis ap endonuclease, putative 0.0056 0.0044 0.1506
Loa Loa (eye worm) hypothetical protein 0.0109 0.0111 0.011
Loa Loa (eye worm) hypothetical protein 0.0023 0.0002 0.0002
Schistosoma mansoni hypothetical protein 0.0068 0.0059 0.0058
Loa Loa (eye worm) hypothetical protein 0.0023 0.0002 0.0002
Loa Loa (eye worm) AGC/PKC/ALPHA protein kinase 0.0465 0.0558 0.0557
Onchocerca volvulus 0.0035 0.0017 0.0051
Onchocerca volvulus 0.005 0.0036 0.0107
Onchocerca volvulus 0.0234 0.0267 0.0804
Schistosoma mansoni serine/threonine protein kinase 0.0907 0.1115 0.1114
Schistosoma mansoni nAChR subunit 0.005 0.0036 0.0036
Schistosoma mansoni histamine h1 receptor 0.0109 0.0111 0.011
Brugia malayi Hr1 repeat family protein 0.0237 0.0272 0.0272
Schistosoma mansoni biogenic amine (5HT) receptor 0.0109 0.0111 0.011
Brugia malayi Cytochrome P450 family protein 0.0028 0.0009 0.0009
Loa Loa (eye worm) acetylcholine receptor protein 0.0023 0.0002 0.0002
Brugia malayi Pleckstrin Homology Domain 0.0224 0.0256 0.0256
Entamoeba histolytica recQ family helicase, putative 0.0022 0.0002 0.0025
Schistosoma mansoni opsin-like receptor 0.0109 0.0111 0.011
Echinococcus multilocularis Cys loop ligand gated ion channel subunit 0.005 0.0036 0.0036
Echinococcus multilocularis neuropeptide Y receptor 0.0109 0.0111 0.011
Loa Loa (eye worm) hypothetical protein 0.0829 0.1016 0.1016
Echinococcus granulosus neuropeptides capa receptor 0.0109 0.0111 0.011
Schistosoma mansoni histone-lysine n-methyltransferase setb1 0.0029 0.0011 0.001
Schistosoma mansoni Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) 0.0046 0.0032 0.0031
Loa Loa (eye worm) GABA receptor subunit 0.0027 0.0007 0.0007
Brugia malayi 6-phosphofructokinase 0.011 0.0112 0.0112
Echinococcus multilocularis tm gpcr rhodopsin gpcr rhodopsin superfamily 0.0109 0.0111 0.011
Echinococcus multilocularis nicotinic acetylcholine receptor beta 1 subunit 0.005 0.0036 0.0036
Brugia malayi Cation transporter family protein 0.005 0.0036 0.0036
Echinococcus granulosus 5'partial|histone lysine N methyltransferase SETDB2 0.0028 0.0009 0.0009
Loa Loa (eye worm) nicotinic acetylcholine receptor alpha subunit 0.005 0.0036 0.0036
Loa Loa (eye worm) hypothetical protein 0.0109 0.0111 0.011
Loa Loa (eye worm) hypothetical protein 0.0027 0.0007 0.0007
Mycobacterium tuberculosis Probable nitrite reductase [NAD(P)H] large subunit [FAD flavoprotein] NirB 0.0106 0.0107 0.403
Trichomonas vaginalis phosphofructokinase, putative 0.003 0.0011 0.0368
Loa Loa (eye worm) hypothetical protein 0.0026 0.0006 0.0006
Onchocerca volvulus 0.0035 0.0017 0.0051
Onchocerca volvulus 0.0023 0.0002 0.0006
Toxoplasma gondii hypothetical protein 0.0091 0.0088 0.0087
Loa Loa (eye worm) hypothetical protein 0.0027 0.0007 0.0007
Echinococcus multilocularis microtubule associated protein 2 0.069 0.0841 0.0841
Brugia malayi RhoGAP domain containing protein 0.0212 0.024 0.024
Echinococcus multilocularis orexin receptor type 2 0.0109 0.0111 0.011
Onchocerca volvulus 0.012 0.0125 0.0374
Loa Loa (eye worm) hypothetical protein 0.0032 0.0014 0.0013
Brugia malayi larval opioid receptor 0.0109 0.0111 0.0111
Loa Loa (eye worm) hypothetical protein 0.0829 0.1016 0.1016
Loa Loa (eye worm) hypothetical protein 0.3974 0.4972 0.4971
Echinococcus granulosus serine:threonine protein kinase N2 0.0237 0.0272 0.0271
Brugia malayi Cation transporter family protein 0.005 0.0036 0.0036
Echinococcus multilocularis telomerase reverse transcriptase subunit 0.0437 0.0523 0.0522
Schistosoma mansoni diacylglycerol kinase theta 0.0212 0.024 0.024
Schistosoma mansoni Cys-loop ligand gated ion channel subunit 0.005 0.0036 0.0036
Brugia malayi hypothetical protein 0.0023 0.0002 0.0002
Echinococcus multilocularis GPCR, family 2 0.0031 0.0013 0.0013
Echinococcus granulosus DNA apurinic or apyrimidinic site lyase 0.0056 0.0044 0.0043
Echinococcus multilocularis neuropeptides capa receptor 0.0109 0.0111 0.011
Loa Loa (eye worm) hypothetical protein 0.0229 0.0262 0.0262
Leishmania major apurinic/apyrimidinic endonuclease-redox protein 0.0056 0.0044 0.0058
Echinococcus granulosus microtubule associated protein 2 0.069 0.0841 0.0841
Brugia malayi RhoGAP domain containing protein 0.0212 0.024 0.024
Loa Loa (eye worm) neuropeptide F receptor 0.0109 0.0111 0.011
Schistosoma mansoni biogenic amine (octopamine/dopamine) receptor 0.0109 0.0111 0.011
Onchocerca volvulus 0.0109 0.0111 0.0333
Echinococcus granulosus g protein linked acetylcholine receptor gar 2a 0.0109 0.0111 0.011
Plasmodium vivax ADP-dependent DNA helicase RecQ, putative 0.0028 0.0009 0.0009
Echinococcus granulosus neuropeptide receptor 0.0109 0.0111 0.011
Schistosoma mansoni hypothetical protein 0.0212 0.024 0.024
Echinococcus multilocularis tyrosyl DNA phosphodiesterase 1 0.0067 0.0058 0.0057
Echinococcus granulosus Ribosomal protein S1 RNA binding domain 0.0053 0.0041 0.004
Onchocerca volvulus 0.005 0.0036 0.0107
Echinococcus multilocularis thioredoxin glutathione reductase 0.0047 0.0032 0.0032
Brugia malayi Tyrosyl-DNA phosphodiesterase family protein 0.0067 0.0058 0.0058
Echinococcus multilocularis serine:threonine protein kinase MRCK beta 0.0219 0.0248 0.0248
Loa Loa (eye worm) abnormal catecholamine distribution protein 1 0.019 0.0213 0.0212
Schistosoma mansoni inositol monophosphatase 0.0036 0.0018 0.0018
Brugia malayi Serotonin receptor 0.0109 0.0111 0.0111
Loa Loa (eye worm) O-glycosyl hydrolase family 30 protein 0.0249 0.0287 0.0287
Onchocerca volvulus 0.0109 0.0111 0.0333
Loa Loa (eye worm) hypothetical protein 0.0035 0.0017 0.0017
Schistosoma mansoni peptide (FMRFamide/neurokinin-3)-like receptor 0.0109 0.0111 0.011
Schistosoma mansoni glutamate receptor NMDA 0.0237 0.0271 0.0271
Schistosoma mansoni hypothetical protein 0.0031 0.0013 0.0013
Loa Loa (eye worm) RNA recognition domain-containing protein domain-containing protein 0.0062 0.0052 0.0051
Loa Loa (eye worm) hypothetical protein 0.0109 0.0111 0.011
Schistosoma mansoni DNA topoisomerase type I 0.7972 1 1
Echinococcus multilocularis survival motor neuron protein 1 0.0229 0.0262 0.0262
Echinococcus multilocularis rhodopsin orphan GPCR 0.0109 0.0111 0.011
Schistosoma mansoni lipoxygenase 0.0084 0.0079 0.0078
Echinococcus granulosus rhodopsin orphan GPCR 0.0109 0.0111 0.011
Loa Loa (eye worm) cytochrome P450 0.0028 0.0009 0.0008
Echinococcus granulosus glutamate receptor ionotrophic AMPA 3 0.0159 0.0174 0.0173
Schistosoma mansoni Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) 0.0046 0.0032 0.0031
Plasmodium vivax amine transporter, putative 0.0091 0.0088 0.0087
Schistosoma mansoni alpha-1 adrenergic receptor 0.0109 0.0111 0.011
Trypanosoma brucei tyrosyl-DNA Phosphodiesterase (Tdp1), putative 0.0067 0.0058 0.0077
Loa Loa (eye worm) serotonin transporter b 0.0535 0.0647 0.0646
Schistosoma mansoni aryl hydrocarbon receptor 0.0048 0.0034 0.0034
Loa Loa (eye worm) hypothetical protein 0.0027 0.0007 0.0007
Echinococcus multilocularis allatostatin A receptor 0.0109 0.0111 0.011
Trypanosoma cruzi DNA topoisomerase type IB small subunit, putative 0.2003 0.2493 0.3332
Echinococcus granulosus serine:threonine protein kinase N2 0.0421 0.0503 0.0502
Schistosoma mansoni adenoreceptor 0.0109 0.0111 0.011
Echinococcus multilocularis gamma aminobutyric acid receptor subunit 0.0023 0.0002 0.0002
Schistosoma mansoni lamin 0.0026 0.0007 0.0006
Loa Loa (eye worm) hypothetical protein 0.059 0.0716 0.0715
Brugia malayi Neurotransmitter-gated ion-channel ligand binding domain containing protein 0.005 0.0036 0.0036
Loa Loa (eye worm) hypothetical protein 0.0091 0.0088 0.0087
Loa Loa (eye worm) ligand-Gated ion Channel family member 0.005 0.0036 0.0036
Entamoeba histolytica pyrophosphate-dependent phosphofructokinase 0.003 0.0011 0.0204
Plasmodium falciparum amino acid transporter, putative 0.0091 0.0088 0.0087
Plasmodium vivax 6-phosphofructokinase, putative 0.003 0.0011 0.0011
Entamoeba histolytica hypothetical protein 0.0027 0.0007 0.013
Loa Loa (eye worm) hypothetical protein 0.0437 0.0523 0.0522
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0109 0.0111 0.011
Echinococcus granulosus ribosomal protein S6 kinase alpha 3 0.0237 0.0272 0.0271
Loa Loa (eye worm) beta-LACTamase domain containing family member 0.0035 0.0017 0.0017
Onchocerca volvulus 0.0035 0.0017 0.0051
Echinococcus granulosus survival motor neuron protein 1 0.0229 0.0262 0.0262
Plasmodium vivax hypothetical protein, conserved 0.0091 0.0088 0.0087
Brugia malayi putative neuropeptide receptor 0.0109 0.0111 0.0111
Onchocerca volvulus 0.0109 0.0111 0.0333
Onchocerca volvulus 0.0578 0.07 0.2107
Echinococcus multilocularis 0.0028 0.0009 0.0008
Schistosoma mansoni nAChR subunit 0.005 0.0036 0.0036
Echinococcus multilocularis g protein coupled receptor 0.0109 0.0111 0.011
Onchocerca volvulus 0.0026 0.0007 0.0019
Echinococcus multilocularis rhodopsin orphan GPCR 0.0109 0.0111 0.011
Echinococcus granulosus neuropeptide FF receptor 2 0.0109 0.0111 0.011
Onchocerca volvulus 0.0029 0.0011 0.003
Brugia malayi sulfakinin receptor protein 0.0109 0.0111 0.0111
Schistosoma mansoni ap endonuclease 0.0056 0.0044 0.0043
Loa Loa (eye worm) norepinephrine transporter 0.0535 0.0647 0.0646
Plasmodium vivax hypothetical protein, conserved 0.0035 0.0017 0.0017
Echinococcus granulosus Cys loop ligand gated ion channel subunit 0.0023 0.0002 0.0002
Loa Loa (eye worm) AGC/RSK/P70 protein kinase 0.0237 0.0272 0.0271
Echinococcus multilocularis G protein coupled 5 hydroxytryptamine receptor 0.0109 0.0111 0.011
Echinococcus multilocularis rhodopsin orphan GPCR 0.0109 0.0111 0.011
Echinococcus granulosus allatostatin A receptor 0.0109 0.0111 0.011
Trypanosoma cruzi C-8 sterol isomerase, putative 0.3974 0.4972 0.6646
Trypanosoma brucei cAMP binding protein, putative 0.0026 0.0007 0.0008
Loa Loa (eye worm) hypothetical protein 0.1041 0.1283 0.1282
Trypanosoma brucei cytochrome P450, putative 0.0037 0.002 0.0026
Echinococcus granulosus lamin 0.0026 0.0007 0.0006
Loa Loa (eye worm) hypothetical protein 0.0212 0.024 0.024
Brugia malayi acetylcholine receptor protein, alpha-like chain, putative 0.005 0.0036 0.0036
Toxoplasma gondii histone lysine methyltransferase SET/SUV39 0.0029 0.0011 0.001
Toxoplasma gondii hypothetical protein 0.0091 0.0088 0.0087
Echinococcus granulosus glycine receptor subunit beta 0.005 0.0036 0.0036
Echinococcus granulosus intermediate filament protein 0.0026 0.0007 0.0006
Echinococcus multilocularis glutamate receptor 2 0.0106 0.0107 0.0106
Trypanosoma cruzi sterol C-24 reductase, putative 0.0048 0.0034 0.0045
Loa Loa (eye worm) cytochrome P450 family protein 0.0037 0.002 0.002
Loa Loa (eye worm) hypothetical protein 0.0035 0.0017 0.0017
Brugia malayi Cytochrome P450 family protein 0.0037 0.002 0.002
Echinococcus multilocularis biogenic amine (5HT) receptor 0.0109 0.0111 0.011
Loa Loa (eye worm) hypothetical protein 0.0109 0.0111 0.011
Echinococcus granulosus alpha 1A adrenergic receptor 0.0109 0.0111 0.011
Schistosoma mansoni serine/threonine protein kinase 0.0219 0.0248 0.0248
Trypanosoma cruzi ATP-dependent DEAD/H DNA helicase recQ, putative 0.0022 0.0002 0.0002
Echinococcus granulosus g protein linked acetylcholine receptor gar 2a 0.0109 0.0111 0.011
Schistosoma mansoni glutamate receptor kainate 0.0144 0.0155 0.0155
Trypanosoma cruzi cytochrome p450-like protein, putative 0.0028 0.0009 0.0011
Trichomonas vaginalis glucosylceramidase, putative 0.0249 0.0287 0.9997
Echinococcus multilocularis musashi 0.0026 0.0007 0.0006
Plasmodium vivax 6-phosphofructokinase, putative 0.003 0.0011 0.0011
Echinococcus multilocularis G-protein coupled receptor, putative 0.0109 0.0111 0.011
Loa Loa (eye worm) hypothetical protein 0.005 0.0036 0.0036
Brugia malayi Neurotransmitter-gated ion-channel ligand binding domain containing protein 0.005 0.0036 0.0036
Echinococcus granulosus biogenic amine 5HT receptor 0.0109 0.0111 0.011
Loa Loa (eye worm) hypothetical protein 0.005 0.0036 0.0036
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0109 0.0111 0.011
Echinococcus multilocularis nicotinic acetylcholine receptor subunit alpha 8 0.005 0.0036 0.0036
Trichomonas vaginalis glucosylceramidase, putative 0.0164 0.0179 0.6236
Schistosoma mansoni hypothetical protein 0.0047 0.0032 0.0032
Mycobacterium leprae PROBABLE 6-PHOSPHOFRUCTOKINASE PFKA (PHOSPHOHEXOKINASE) (PHOSPHOFRUCTOKINASE) 0.011 0.0112 0.9132
Brugia malayi phosphofructokinase 0.011 0.0112 0.0112
Trypanosoma cruzi tyrosyl-DNA Phosphodiesterase (Tdp1), putative 0.0067 0.0058 0.0077
Brugia malayi Sodium:neurotransmitter symporter family protein 1, putative 0.0091 0.0088 0.0088
Schistosoma mansoni glutamate receptor kainate 0.0144 0.0155 0.0155
Onchocerca volvulus 0.0109 0.0111 0.0333
Mycobacterium ulcerans hypothetical protein 0.0035 0.0017 0.0805
Echinococcus multilocularis sodium:chloride dependent neurotransmitter 0.0091 0.0088 0.0087
Mycobacterium tuberculosis Probable membrane NADH dehydrogenase NdhA 0.0106 0.0107 0.403
Echinococcus granulosus glutamate receptor 2 0.0106 0.0107 0.0106
Echinococcus granulosus nicotinic acetylcholine receptor alpha subunit 0.005 0.0036 0.0036
Loa Loa (eye worm) hypothetical protein 0.0649 0.0789 0.0789
Trichomonas vaginalis D-aminoacylase, putative 0.0035 0.0017 0.0585
Loa Loa (eye worm) hypothetical protein 0.005 0.0036 0.0036
Entamoeba histolytica phosphofructokinase, putative 0.011 0.0112 0.2161
Trichomonas vaginalis AGC family protein kinase 0.0237 0.0272 0.946
Echinococcus granulosus vesicular acetylcholine transporter 0.2661 0.332 0.332
Schistosoma mansoni sodium/chloride dependent transporter 0.0091 0.0088 0.0087
Trichomonas vaginalis phosphofructokinase, putative 0.011 0.0112 0.3901
Leishmania major hypothetical protein, conserved 0.0021 0 0.0000000034972
Trichomonas vaginalis glucosylceramidase, putative 0.0164 0.0179 0.6236
Echinococcus multilocularis lamin 0.0026 0.0007 0.0006
Echinococcus multilocularis neuropeptide receptor 0.0109 0.0111 0.011
Schistosoma mansoni thyrotropin-releasing hormone receptor 0.0109 0.0111 0.011
Toxoplasma gondii thioredoxin reductase 0.0047 0.0032 0.0032
Loa Loa (eye worm) hypothetical protein 0.0109 0.0111 0.011
Loa Loa (eye worm) hypothetical protein 0.0366 0.0433 0.0433
Echinococcus granulosus 6 phosphofructokinase 0.011 0.0112 0.0112
Echinococcus multilocularis potassium voltage gated channel subfamily H 0.0037 0.002 0.0019
Echinococcus granulosus g protein coupled receptor 0.0109 0.0111 0.011
Schistosoma mansoni serine/threonine protein kinase 0.0885 0.1087 0.1087
Loa Loa (eye worm) G-protein-linked acetylcholine receptor protein 2 0.0109 0.0111 0.011
Brugia malayi Neurotransmitter-gated ion-channel ligand binding domain containing protein 0.0023 0.0002 0.0002
Brugia malayi Protein kinase domain containing protein 0.025 0.0287 0.0287
Brugia malayi hypothetical protein 0.0023 0.0002 0.0002
Brugia malayi acetylcholine receptor, alpha-type subunit unc-38 precursor 0.005 0.0036 0.0036
Echinococcus multilocularis DNA topoisomerase 1 0.7972 1 1
Echinococcus granulosus G protein coupled 5 hydroxytryptamine receptor 0.0109 0.0111 0.011
Mycobacterium leprae DIHYDROLIPOAMIDE DEHYDROGENASE LPD (LIPOAMIDE REDUCTASE (NADH)) (LIPOYL DEHYDROGENASE) (DIHYDROLIPOYL DEHYDROGENASE) (DIAPHORASE 0.0118 0.0122 1
Echinococcus multilocularis Glutamate receptor, ionotropic kainate 3 0.0053 0.0041 0.004
Loa Loa (eye worm) hypothetical protein 0.0109 0.0111 0.011
Loa Loa (eye worm) hypothetical protein 0.012 0.0125 0.0124
Onchocerca volvulus Neuropeptide F receptor homolog 0.0109 0.0111 0.0333
Echinococcus granulosus nmda type glutamate receptor 0.0131 0.0138 0.0138
Echinococcus multilocularis NMDA receptor 0.0053 0.0041 0.004
Echinococcus multilocularis nAChR subunit 0.005 0.0036 0.0036
Mycobacterium ulcerans extragenic suppressor protein SuhB 0.0036 0.0018 0.0915
Brugia malayi protein kinase C3,putative 0.0466 0.056 0.056
Giardia lamblia Endonuclease/Exonuclease/phosphatase 0.0056 0.0044 1
Loa Loa (eye worm) glutamate-gated chloride channel alpha3A subunit 0.005 0.0036 0.0036
Echinococcus granulosus hypothetical protein 0.0109 0.0111 0.011
Brugia malayi Thioredoxin reductase 0.0047 0.0032 0.0032
Schistosoma mansoni sodium/chloride dependent neurotransmitter transporter 0.0091 0.0088 0.0087
Echinococcus granulosus GPCR family 2 0.0031 0.0013 0.0013
Loa Loa (eye worm) hypothetical protein 0.0212 0.024 0.024
Brugia malayi Hypothetical glycine receptor like protein T20B12.9 in chromosome III 0.0027 0.0007 0.0007
Loa Loa (eye worm) hypothetical protein 0.0068 0.0059 0.0058
Echinococcus granulosus lamin dm0 0.0026 0.0007 0.0006
Schistosoma mansoni tar DNA-binding protein 0.0062 0.0052 0.0051
Loa Loa (eye worm) AGC/RSK/RSK protein kinase 0.0237 0.0272 0.0271
Schistosoma mansoni family A2 unassigned peptidase (A02 family) 0.0278 0.0323 0.0322
Brugia malayi C1-like domain containing protein 0.0584 0.0708 0.0708
Brugia malayi vesicular acetylcholine transporter unc-17 0.2661 0.332 0.332
Loa Loa (eye worm) hypothetical protein 0.005 0.0036 0.0036
Loa Loa (eye worm) hypothetical protein 0.0535 0.0647 0.0646
Echinococcus granulosus unc 13 munc13 0.0234 0.0267 0.0267
Loa Loa (eye worm) hypothetical protein 0.005 0.0036 0.0036
Mycobacterium tuberculosis Probable dehydrogenase 0.0106 0.0107 0.403
Brugia malayi Neurotransmitter-gated ion-channel ligand binding domain containing protein 0.005 0.0036 0.0036
Schistosoma mansoni peptide (FMRFamide/somatostatin)-like receptor 0.0109 0.0111 0.011
Echinococcus granulosus sodium dependent neurotransmitter transporter 0.0091 0.0088 0.0087
Onchocerca volvulus 0.0109 0.0111 0.0333
Echinococcus multilocularis serotonin receptor 0.0109 0.0111 0.011
Mycobacterium tuberculosis Probable lipase LipD 0.0035 0.0017 0.0341
Entamoeba histolytica protein kinase, putative 0.025 0.0287 0.554
Echinococcus granulosus neuronal acetylcholine receptor subunit alpha 4 0.005 0.0036 0.0036
Trichomonas vaginalis glucosylceramidase, putative 0.0249 0.0287 0.9997
Echinococcus granulosus Glutamate receptor ionotropic kainate 2 0.0159 0.0174 0.0173
Mycobacterium tuberculosis Possible penicillin-binding protein 0.0222 0.0253 1
Schistosoma mansoni hypothetical protein 0.0109 0.0111 0.011
Brugia malayi G-protein coupled receptor 0.0109 0.0111 0.0111
Loa Loa (eye worm) AGC/DMPK/GEK protein kinase 0.0237 0.0272 0.0271
Echinococcus granulosus pyroglutamylated rfamide peptide receptor 0.0109 0.0111 0.011
Schistosoma mansoni peptide (allatostatin)-like receptor 0.0109 0.0111 0.011
Onchocerca volvulus 0.0026 0.0007 0.0019
Echinococcus multilocularis arachidonate 5 lipoxygenase 0.012 0.0124 0.0124
Loa Loa (eye worm) hypothetical protein 0.0035 0.0017 0.0017
Schistosoma mansoni biogenic amine (dopamine) receptor 0.0109 0.0111 0.011
Schistosoma mansoni neuropeptide f receptor 76f 0.0109 0.0111 0.011
Brugia malayi GnHR receptor homolog 0.0109 0.0111 0.0111
Brugia malayi Neurotransmitter-gated ion-channel transmembrane region family protein 0.005 0.0036 0.0036
Loa Loa (eye worm) hypothetical protein 0.0035 0.0017 0.0017
Echinococcus multilocularis histone lysine N methyltransferase SETMAR 0.0029 0.0011 0.001
Brugia malayi hypoxia-induced factor 1 0.015 0.0162 0.0162
Schistosoma mansoni 6-phosphofructokinase 0.011 0.0112 0.0112
Schistosoma mansoni hypothetical protein 0.0109 0.0111 0.011
Schistosoma mansoni neurotransmitter gated ion channel 0.0023 0.0002 0.0002
Echinococcus multilocularis 7TM GPCR, rhodopsin 0.0109 0.0111 0.011
Trichomonas vaginalis phosphofructokinase, putative 0.003 0.0011 0.0368
Loa Loa (eye worm) hypothetical protein 0.005 0.0036 0.0036
Echinococcus granulosus synaptic vesicular amine transporter 0.019 0.0213 0.0212
Echinococcus granulosus guanine nucleotide binding protein Gs subunit 0.0046 0.0032 0.0031
Schistosoma mansoni biogenic amine (dopamine) receptor 0.0109 0.0111 0.011
Loa Loa (eye worm) hypothetical protein 0.0097 0.0096 0.0095
Brugia malayi O-Glycosyl hydrolase family 30 protein 0.0249 0.0287 0.0287
Echinococcus multilocularis rhodopsin orphan GPCR 0.0109 0.0111 0.011
Loa Loa (eye worm) hypothetical protein 0.0027 0.0007 0.0007
Brugia malayi hypothetical protein 0.0109 0.0111 0.0111
Loa Loa (eye worm) hypothetical protein 0.0109 0.0111 0.011
Echinococcus granulosus ribosomal protein s6 kinase beta 1 0.0237 0.0272 0.0271
Echinococcus multilocularis growth hormone secretagogue receptor type 1 0.0109 0.0111 0.011
Toxoplasma gondii Sodium:neurotransmitter symporter family protein 0.0091 0.0088 0.0087
Loa Loa (eye worm) hypothetical protein 0.0234 0.0267 0.0267
Loa Loa (eye worm) hypothetical protein 0.0048 0.0034 0.0034
Loa Loa (eye worm) hypothetical protein 0.0109 0.0111 0.011
Brugia malayi bHLH-PAS transcription factor 0.0036 0.0019 0.0019
Loa Loa (eye worm) hypoxia-induced factor 1 0.015 0.0162 0.0162
Brugia malayi G protein-coupled receptor 0.0109 0.0111 0.0111
Loa Loa (eye worm) hypothetical protein 0.005 0.0036 0.0036
Brugia malayi Protein kinase c protein 2 0.0677 0.0825 0.0825
Plasmodium vivax AP endonuclease (DNA-[apurinic or apyrimidinic site] lyase), putative 0.0056 0.0044 0.0043
Loa Loa (eye worm) voltage and ligand gated potassium channel 0.0037 0.002 0.0019
Echinococcus granulosus Rac GTPase activating protein 1 0.0212 0.024 0.024
Schistosoma mansoni hypothetical protein 0.0053 0.0041 0.004
Loa Loa (eye worm) hypothetical protein 0.0091 0.0088 0.0087
Brugia malayi Unidentified vitellogenin-linked transcript protein 6, putative 0.0109 0.0111 0.0111
Schistosoma mansoni opsin-like receptor 0.0109 0.0111 0.011
Loa Loa (eye worm) GTP-binding regulatory protein Gs alpha-S chain 0.0046 0.0032 0.0031
Echinococcus multilocularis glutamate (NMDA) receptor subunit 0.0307 0.0359 0.0359
Trypanosoma brucei ATP-dependent DEAD/H DNA helicase recQ, putative 0.0022 0.0002 0.0002
Echinococcus multilocularis alpha 1A adrenergic receptor 0.0109 0.0111 0.011
Plasmodium falciparum glutathione reductase 0.0047 0.0032 0.0032
Schistosoma mansoni histone-lysine n-methyltransferase setb1 0.0029 0.0011 0.001
Leishmania major cytochrome p450-like protein 0.0028 0.0009 0.0011
Echinococcus granulosus protein kinase c eta type 0.0212 0.024 0.024
Schistosoma mansoni serine/threonine protein kinase 0.0237 0.0272 0.0271
Brugia malayi Variant SH3 domain containing protein 0.0034 0.0016 0.0016
Brugia malayi Serotonin/octopamine receptor family protein 7 0.0109 0.0111 0.0111
Toxoplasma gondii ATP-dependent DNA helicase, RecQ family protein 0.0028 0.0009 0.0008
Loa Loa (eye worm) pre-SET domain-containing protein family protein 0.0205 0.0232 0.0231
Echinococcus multilocularis g protein linked acetylcholine receptor gar 2a 0.0109 0.0111 0.011
Plasmodium falciparum ATP-dependent 6-phosphofructokinase 0.003 0.0011 0.0011
Schistosoma mansoni sodium/chloride dependent neurotransmitter transporter 0.0091 0.0088 0.0087
Brugia malayi hypothetical protein 0.0109 0.0111 0.0111
Echinococcus multilocularis lamin dm0 0.0026 0.0007 0.0006
Brugia malayi Dopamine receptor protein 2 0.0109 0.0111 0.0111
Schistosoma mansoni biogenic amine receptor 0.0109 0.0111 0.011
Echinococcus granulosus neuropeptide receptor 0.0109 0.0111 0.011
Echinococcus multilocularis uncharacterized sodium dependent transporter 0.0091 0.0088 0.0087
Echinococcus granulosus DNA topoisomerase 1 0.7972 1 1
Mycobacterium ulcerans esterase/lipase LipP 0.0035 0.0017 0.0805
Loa Loa (eye worm) hypothetical protein 0.0091 0.0088 0.0087
Brugia malayi Iron-sulfur cluster assembly accessory protein 0.0047 0.0032 0.0032
Mycobacterium ulcerans cytochrome P450 185A4 Cyp185A4 0.0037 0.002 0.1082
Schistosoma mansoni chimerin-related rho-gtpase-activating protein 0.0212 0.024 0.024
Trypanosoma cruzi PAB1-binding protein , putative 0.0026 0.0006 0.0007
Echinococcus multilocularis inositol monophosphatase 1 0.0036 0.0018 0.0018
Onchocerca volvulus 0.0109 0.0111 0.0333
Schistosoma mansoni lamin 0.0026 0.0007 0.0006
Echinococcus granulosus protein kinase c iota type 0.0697 0.085 0.085
Loa Loa (eye worm) hypothetical protein 0.0023 0.0002 0.0002
Echinococcus multilocularis serine:threonine protein kinase N2 0.0237 0.0272 0.0271
Schistosoma mansoni serine/threonine protein kinase 0.0237 0.0272 0.0271
Mycobacterium tuberculosis Probable reductase 0.0106 0.0107 0.403
Schistosoma mansoni protein kinase C 0.0234 0.0267 0.0267
Echinococcus multilocularis transfer RNA-Lys 0.0036 0.0019 0.0018
Onchocerca volvulus 0.0109 0.0111 0.0333
Loa Loa (eye worm) hypothetical protein 0.0535 0.0647 0.0646
Schistosoma mansoni nAChR subunit 0.005 0.0036 0.0036
Schistosoma mansoni unc-13 (munc13) 0.0234 0.0267 0.0267
Schistosoma mansoni hypothetical protein 0.0031 0.0013 0.0013
Echinococcus granulosus glycine receptor subunit beta 0.005 0.0036 0.0036
Brugia malayi neuropeptide F receptor 0.0109 0.0111 0.0111
Echinococcus granulosus acetylcholine receptor subunit beta 1 0.005 0.0036 0.0036
Mycobacterium tuberculosis Probable esterase/lipase LipP 0.0035 0.0017 0.0341
Trichomonas vaginalis 6-phosphofructokinase, putative 0.003 0.0011 0.0368
Echinococcus granulosus diuretic hormone 44 receptor GPRdih2 0.0031 0.0013 0.0013
Echinococcus granulosus tm gpcr rhodopsin 0.0109 0.0111 0.011
Loa Loa (eye worm) LGC-31 protein 0.005 0.0036 0.0036
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0109 0.0111 0.011
Trichomonas vaginalis DNA helicase recq1, putative 0.0042 0.0026 0.0903
Brugia malayi hypothetical protein 0.0026 0.0006 0.0006
Echinococcus granulosus thyrotropin releasing hormone receptor 0.0109 0.0111 0.011
Leishmania major cytochrome p450-like protein 0.0037 0.002 0.0026
Entamoeba histolytica protein kinase, putative 0.0237 0.0272 0.524
Echinococcus granulosus sodium and chloride dependent glycine 0.0091 0.0088 0.0087
Plasmodium falciparum ADP-dependent DNA helicase RecQ 0.0037 0.002 0.0019
Brugia malayi Pre-SET motif family protein 0.0029 0.0011 0.0011
Plasmodium vivax glutathione reductase, putative 0.0047 0.0032 0.0032
Echinococcus granulosus neuropeptide receptor A26 0.0109 0.0111 0.011
Toxoplasma gondii LsmAD domain-containing protein 0.0026 0.0006 0.0005
Onchocerca volvulus Vesicular acetylcholine transporter homolog 0.2661 0.332 1
Loa Loa (eye worm) hypothetical protein 0.0091 0.0088 0.0087
Echinococcus multilocularis nicotinic acetylcholine receptor alpha subunit 0.005 0.0036 0.0036
Loa Loa (eye worm) hypothetical protein 0.005 0.0036 0.0036
Brugia malayi G-protein coupled receptor 0.0109 0.0111 0.0111
Loa Loa (eye worm) hypothetical protein 0.005 0.0036 0.0036
Echinococcus multilocularis protein kinase c epsilon type 0.0885 0.1087 0.1087
Brugia malayi Phorbol esters/diacylglycerol binding domain 0.0584 0.0708 0.0708
Echinococcus granulosus biogenic amine 5HT receptor 0.0109 0.0111 0.011
Plasmodium vivax topoisomerase I, putative 0.7972 1 1
Trypanosoma cruzi trypanothione reductase, putative 0.0047 0.0032 0.0042
Echinococcus multilocularis Glutamate receptor, ionotropic kainate 2 0.0159 0.0174 0.0173
Echinococcus granulosus bloom syndrome protein 0.0042 0.0026 0.0026
Echinococcus multilocularis protein kinase c eta type 0.0212 0.024 0.024
Loa Loa (eye worm) solute carrier family 6 member 4 0.0535 0.0647 0.0646
Onchocerca volvulus 0.0109 0.0111 0.0333
Echinococcus granulosus tachykinin peptides receptor 99D 0.0109 0.0111 0.011
Brugia malayi acetylcholine receptor alpha subunit precursor, putative 0.005 0.0036 0.0036
Echinococcus multilocularis glycine receptor subunit alpha 1 0.005 0.0036 0.0036
Mycobacterium ulcerans putative regulatory protein 0.0036 0.0019 0.094
Schistosoma mansoni neuropeptide receptor 0.0109 0.0111 0.011
Schistosoma mansoni voltage-gated potassium channel 0.004 0.0024 0.0024
Echinococcus multilocularis nuclear factor of activated T cells 5 0.0075 0.0068 0.0067
Mycobacterium ulcerans lipase LipD 0.0035 0.0017 0.0805
Brugia malayi Serotonin receptor 0.0109 0.0111 0.0111
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0109 0.0111 0.011
Echinococcus multilocularis rhodopsin orphan GPCR 0.0109 0.0111 0.011
Mycobacterium tuberculosis Conserved protein 0.0035 0.0017 0.0341
Echinococcus multilocularis synaptic vesicular amine transporter 0.019 0.0213 0.0212
Onchocerca volvulus 0.012 0.0125 0.0374
Leishmania major ATP-dependent phosphofructokinase 0.011 0.0112 0.015
Loa Loa (eye worm) hypothetical protein 0.0023 0.0002 0.0002
Trichomonas vaginalis AGC family protein kinase 0.025 0.0287 1
Trichomonas vaginalis phosphofructokinase, putative 0.003 0.0011 0.0368
Loa Loa (eye worm) hypothetical protein 0.0224 0.0256 0.0255
Loa Loa (eye worm) CAMK/PKD protein kinase 0.0584 0.0708 0.0708
Loa Loa (eye worm) hypothetical protein 0.0109 0.0111 0.011
Loa Loa (eye worm) CAMK/PKD protein kinase 0.0372 0.0441 0.0441
Schistosoma mansoni norepinephrine/norepinephrine transporter 0.0091 0.0088 0.0087
Entamoeba histolytica phosphofructokinase, putative 0.011 0.0112 0.2161
Echinococcus granulosus nicotinic acetylcholine receptor a11 subunit 0.005 0.0036 0.0036
Trypanosoma brucei C2 domain/Ankyrin repeats (3 copies), putative 0.0021 0 0.0000000034972
Schistosoma mansoni neuropeptide receptor 0.0109 0.0111 0.011
Trichomonas vaginalis set domain proteins, putative 0.0234 0.0267 0.93
Schistosoma mansoni Lamin B receptor (ERG24) 0.0093 0.0091 0.009
Brugia malayi Latrophilin receptor protein 2 0.0031 0.0013 0.0013
Echinococcus granulosus potassium voltage gated channel subfamily H 0.0037 0.002 0.0019
Echinococcus multilocularis neuropeptide s receptor 0.0109 0.0111 0.011
Schistosoma mansoni nAChR subunit (ShAR1-alpha-like) 0.012 0.0125 0.0124
Schistosoma mansoni sodium-dependent neurotransmitter transporter 0.0091 0.0088 0.0087
Schistosoma mansoni nAChR subunit (ShAR1-beta2-like) 0.005 0.0036 0.0036
Loa Loa (eye worm) hypothetical protein 0.0829 0.1016 0.1016
Leishmania major hypothetical protein, conserved 0.0035 0.0017 0.0022
Schistosoma mansoni serine/threonine protein kinase 0.0212 0.024 0.024
Loa Loa (eye worm) acetylcholine receptor alpha subunit 0.005 0.0036 0.0036
Schistosoma mansoni serine/threonine protein kinase 0.0237 0.0272 0.0271
Echinococcus granulosus serotonin transporter 0.0535 0.0647 0.0646
Loa Loa (eye worm) hypothetical protein 0.0109 0.0111 0.011
Trichomonas vaginalis glucosylceramidase, putative 0.0173 0.019 0.6622

Activities

Activity type Activity value Assay description Source Reference
IC50 (binding) = 1.5 uM Inhibitory activity against HIV-1 protease ChEMBL. 14505679
IC50 (binding) = 1.5 uM Inhibitory activity against HIV-1 protease ChEMBL. 14505679

Phenotypes

Whole-cell/tissue/organism interactions

We have no records of whole-cell/tissue assays done with this compound What does this mean?

Many chemical entities in TDR Targets come from high-throughput screenings with whole cells or tissue samples, and not all assayed compounds have been tested against a single a single target protein, probably because they get ruled out during screening process. Even if these compounds may have not been of interest in the original screening, they may come as interesting leads for other screening assays. Furthermore, we may be able to propose drug-target associations using chemical similarities and network patterns.

Annotated phenotypes:

We have no manually annotated phenotypes for this drug. What does this mean? / Care to help?
In TDR Targets, information about phenotypes that are caused by drugs, or by genetic manipulation of cells (e.g. gene knockouts or knockdowns) is manually curated from the literature. These descriptions help to describe the potential of the target for drug development. If no information is available for this gene or if the information is incomplete, this may mean that i) the papers containing this information either appeared after the curation effort for this organism was carried out or they were inadvertently missed by curators; or that ii) the curation effort for this organism has not yet started.
 
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External resources for this compound

Bibliographic References

1 literature reference was collected for this gene.

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