Detailed information for compound 217432

Basic information

Technical information
  • Name: Unnamed compound
  • MW: 670.709 | Formula: C29H46N6O12
  • H donors: 8 H acceptors: 12 LogP: 0.53 Rotable bonds: 24
    Rule of 5 violations (Lipinski): 4
  • SMILES: CCC[C@H](C(=O)O)NC(=O)[C@@H]1CCCN1C(=O)[C@H](C(C)C)NC(=O)[C@H]([C@H](CC)C)NC(=O)[C@H](C(=O)O)NC(=O)[C@H](C(=O)O)NC(=O)C
  • InChi: 1S/C29H46N6O12/c1-7-10-16(27(42)43)31-22(37)17-11-9-12-35(17)26(41)18(13(3)4)32-23(38)19(14(5)8-2)33-25(40)21(29(46)47)34-24(39)20(28(44)45)30-15(6)36/h13-14,16-21H,7-12H2,1-6H3,(H,30,36)(H,31,37)(H,32,38)(H,33,40)(H,34,39)(H,42,43)(H,44,45)(H,46,47)/t14-,16-,17-,18-,19-,20+,21+/m0/s1
  • InChiKey: UYXBPPUNROUHDL-ZHAJMSDVSA-N  


Substructure search Similarity search

Network

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Synonyms

No synonyms found for this compound

Targets

Known targets for this compound

No curated genes were found associated with this compound

Predicted pathogen targets for this compound

By orthology
No druggable targets predicted by orthology data
By sequence similarity to non orthologous known druggable targets
No druggable targets predicted by sequence similarity
Obtained from network model

Ranking Plot

Putative Targets List

Species Potential target Raw Global Species
Echinococcus multilocularis arachidonate 5 lipoxygenase 0.0113 0.101 0.101
Onchocerca volvulus Peroxidase homolog 0.0025 0.009 0.0106
Schistosoma mansoni tar DNA-binding protein 0.0068 0.0542 0.0626
Loa Loa (eye worm) doublecortin family protein 0.004 0.0247 0.0282
Schistosoma mansoni histamine h1 receptor 0.0022 0.0055 0.0064
Loa Loa (eye worm) hypothetical protein 0.0136 0.1256 0.1445
Schistosoma mansoni hypothetical protein 0.004 0.0247 0.0285
Brugia malayi Neurotransmitter-gated ion-channel transmembrane region family protein 0.0182 0.1739 0.2
Echinococcus multilocularis RUN 0.004 0.0247 0.0247
Brugia malayi Intermediate filament tail domain containing protein 0.0026 0.0097 0.0109
Schistosoma mansoni hepatocyte nuclear factor 4-alpha (hnf-4-alpha) 0.0064 0.0499 0.0576
Loa Loa (eye worm) hypothetical protein 0.0182 0.1739 0.2
Echinococcus multilocularis Regulator of G protein signaling 20 0.0021 0.0041 0.0041
Brugia malayi Iron-sulfur cluster assembly accessory protein 0.0048 0.033 0.0377
Loa Loa (eye worm) hypothetical protein 0.0022 0.0055 0.0061
Mycobacterium leprae Possible regulatory protein 0.0026 0.0097 0.0029
Echinococcus granulosus lipoxygenase domain containing protein 0.004 0.0247 0.0247
Loa Loa (eye worm) follicle stimulating hormone receptor 0.0476 0.4821 0.5551
Schistosoma mansoni nAChR subunit (ShAR1-beta2-like) 0.0182 0.1739 0.2007
Echinococcus multilocularis bloom syndrome protein 0.0044 0.0285 0.0285
Schistosoma mansoni nAChR subunit 0.0084 0.0707 0.0816
Trichomonas vaginalis voltage and ligand gated potassium channel, putative 0.0034 0.0186 0.0321
Schistosoma mansoni ecdysone-induced protein 78c (dr-78) 0.0072 0.058 0.067
Echinococcus multilocularis acetylcholine receptor subunit beta 1 0.0182 0.1739 0.1739
Schistosoma mansoni peptide (allatostatin/somatostatin)-like receptor 0.0022 0.0055 0.0064
Echinococcus multilocularis rhodopsin orphan GPCR 0.0022 0.0055 0.0055
Brugia malayi amidase 0.0098 0.0858 0.0985
Echinococcus granulosus Nuclear hormone receptor HR96 0.0064 0.0499 0.0499
Brugia malayi Hypothetical glycine receptor like protein T20B12.9 in chromosome III 0.0098 0.0855 0.0982
Brugia malayi Carbonic anhydrase like protein 2 precursor 0.0055 0.0397 0.0455
Echinococcus granulosus Ankyrin 0.0033 0.0167 0.0167
Mycobacterium ulcerans DNA polymerase IV 0.0039 0.0238 0.1381
Trichomonas vaginalis guanylate cyclase, putative 0.0026 0.0097 0.0129
Loa Loa (eye worm) hypothetical protein 0.0136 0.1256 0.1445
Schistosoma mansoni jun-related protein 0.0224 0.218 0.2516
Loa Loa (eye worm) hypothetical protein 0.0136 0.1256 0.1445
Loa Loa (eye worm) hypothetical protein 0.0084 0.0707 0.0811
Mycobacterium ulcerans beta-lactamase 0.0074 0.0602 0.3873
Loa Loa (eye worm) hypothetical protein 0.0064 0.0499 0.0572
Onchocerca volvulus 0.0022 0.0055 0.0031
Mycobacterium tuberculosis Possible cytochrome P450 126 Cyp126 0.0029 0.0126 0.0256
Echinococcus multilocularis thyroid hormone receptor alpha 0.0267 0.2625 0.2625
Echinococcus multilocularis g protein linked acetylcholine receptor gar 2a 0.0022 0.0055 0.0055
Echinococcus multilocularis growth hormone secretagogue receptor type 1 0.0022 0.0055 0.0055
Echinococcus multilocularis Nuclear hormone receptor HR96 0.0064 0.0499 0.0499
Echinococcus multilocularis tachykinin peptides receptor 99D 0.0022 0.0055 0.0055
Brugia malayi Dopamine receptor 0.0022 0.0055 0.0061
Loa Loa (eye worm) hypothetical protein 0.0021 0.0041 0.0044
Schistosoma mansoni neuropeptide receptor 0.0022 0.0055 0.0064
Mycobacterium tuberculosis Probable cytochrome P450 125 Cyp125 0.0029 0.0126 0.0256
Echinococcus multilocularis isocitrate dehydrogenase 0.0017 0.0003 0.0003
Brugia malayi nicotinic acetylcholine receptor beta-1 chain precursor 0.0182 0.1739 0.2
Mycobacterium ulcerans cytochrome P450 142A3 Cyp142A3 0.0029 0.0126 0.0609
Echinococcus multilocularis Protein lozenge 0.0054 0.0394 0.0394
Onchocerca volvulus 0.0084 0.0707 0.1437
Echinococcus granulosus NADP dependent isocitrate dehydrogenase 0.0017 0.0003 0.0003
Trypanosoma cruzi Lanosterol 14-alpha demethylase 0.0029 0.0126 0.041
Onchocerca volvulus Peroxidasin homolog 0.0025 0.009 0.0106
Echinococcus multilocularis 7TM GPCR, rhodopsin 0.0022 0.0055 0.0055
Brugia malayi hypothetical protein 0.0084 0.0707 0.0811
Echinococcus granulosus glycine receptor subunit alpha 1 0.0182 0.1739 0.1739
Entamoeba histolytica hypothetical protein 0.0021 0.0041 0.0043
Schistosoma mansoni regulator of G protein signaling 17 19 20 (rgs17 19 20) 0.0021 0.0041 0.0047
Loa Loa (eye worm) hypothetical protein 0.0237 0.2308 0.2657
Brugia malayi Nuclear hormone receptor-like 1 0.0136 0.1256 0.1445
Echinococcus granulosus nicotinic acetylcholine receptor beta 1 subunit 0.0182 0.1739 0.1739
Onchocerca volvulus 0.0433 0.4371 0.9343
Mycobacterium ulcerans aldehyde dehydrogenase 0.0059 0.0447 0.2811
Echinococcus granulosus cpg binding protein 0.0062 0.048 0.048
Brugia malayi Nuclear hormone receptor family member nhr-31 0.0136 0.1256 0.1445
Loa Loa (eye worm) hypothetical protein 0.0022 0.0055 0.0061
Trypanosoma cruzi carbonic anhydrase-like protein, putative 0.024 0.2341 0.7809
Mycobacterium tuberculosis Possible cytochrome P450 135B1 Cyp135B1 0.0029 0.0126 0.0256
Trichomonas vaginalis conserved hypothetical protein 0.0036 0.0203 0.0359
Brugia malayi Pre-SET motif family protein 0.0059 0.0446 0.0511
Brugia malayi Death domain containing protein 0.0032 0.0164 0.0186
Brugia malayi PXA domain containing protein 0.0021 0.0041 0.0044
Echinococcus granulosus regulator of G protein signaling 3 0.0021 0.0041 0.0041
Loa Loa (eye worm) hypothetical protein 0.0055 0.0397 0.0455
Plasmodium falciparum carbonic anhydrase 0.0055 0.0397 0.2671
Loa Loa (eye worm) hypothetical protein 0.0022 0.0055 0.0061
Echinococcus granulosus DNA apurinic or apyrimidinic site lyase 0.002 0.0037 0.0037
Schistosoma mansoni biogenic amine (dopamine) receptor 0.0022 0.0055 0.0064
Toxoplasma gondii ATP-dependent DNA helicase, RecQ family protein 0.0018 0.0014 0.0075
Loa Loa (eye worm) AGC/GRK/BARK protein kinase 0.0021 0.0041 0.0044
Schistosoma mansoni hypothetical protein 0.0029 0.0126 0.0145
Mycobacterium leprae Conserved hypothetical protein 0.0029 0.0126 0.0237
Loa Loa (eye worm) excitatory GABA receptor EXP-1A 0.0182 0.1739 0.2
Echinococcus multilocularis nicotinic acetylcholine receptor beta 1 subunit 0.0182 0.1739 0.1739
Brugia malayi Cytochrome P450 family protein 0.0056 0.0408 0.0466
Echinococcus granulosus lamin 0.0026 0.0097 0.0097
Echinococcus multilocularis histone lysine N methyltransferase MLL3 0.002 0.0038 0.0038
Schistosoma mansoni carbonic anhydrase II (carbonate dehydratase II) 0.024 0.2341 0.2702
Brugia malayi Cation transporter family protein 0.0182 0.1739 0.2
Onchocerca volvulus 0.0022 0.0055 0.0031
Onchocerca volvulus Putative hydroxypyruvate isomerase 0.0041 0.0259 0.0471
Onchocerca volvulus Nuclear receptor subfamily 6 group A member 1 homolog 0.0064 0.0499 0.0989
Brugia malayi hypothetical protein 0.0022 0.0055 0.0061
Loa Loa (eye worm) hypothetical protein 0.0182 0.1739 0.2
Loa Loa (eye worm) hypothetical protein 0.0098 0.0855 0.0982
Echinococcus multilocularis geminin 0.0528 0.5369 0.5369
Brugia malayi acetylcholine receptor alpha subunit precursor, putative 0.0182 0.1739 0.2
Echinococcus granulosus aldehyde dehydrogenase mitochondrial 0.0059 0.0447 0.0447
Loa Loa (eye worm) hypothetical protein 0.0022 0.0055 0.0061
Brugia malayi cytochrome P450 0.0029 0.0126 0.0142
Loa Loa (eye worm) hypothetical protein 0.0053 0.0385 0.044
Brugia malayi Animal haem peroxidase family protein 0.0025 0.009 0.0101
Schistosoma mansoni steroid hormone receptor ad4bp 0.0136 0.1256 0.145
Trypanosoma brucei DNA polymerase kappa, putative 0.0039 0.0238 0.0787
Brugia malayi tailless protein 0.0064 0.0499 0.0572
Echinococcus granulosus g protein linked acetylcholine receptor gar 2a 0.0022 0.0055 0.0055
Echinococcus granulosus bloom syndrome protein 0.0044 0.0285 0.0285
Brugia malayi RNA binding protein 0.0068 0.0542 0.0622
Onchocerca volvulus 0.0025 0.009 0.0106
Schistosoma mansoni neuropeptide receptor 0.0022 0.0055 0.0064
Schistosoma mansoni metabotropic glutamate receptor 2 3 (mglur group 2) 0.0021 0.0041 0.0047
Loa Loa (eye worm) hypothetical protein 0.0088 0.0743 0.0853
Loa Loa (eye worm) hypothetical protein 0.0026 0.0097 0.0109
Mycobacterium tuberculosis Probable aldehyde dehydrogenase 0.0059 0.0447 0.0927
Brugia malayi F/Y-rich N-terminus family protein 0.002 0.0035 0.0038
Echinococcus granulosus carbonic anhydrase II 0.024 0.2341 0.2341
Brugia malayi metabotropic GABA-B receptor subtype 2 0.0278 0.2747 0.3162
Plasmodium vivax ADP-dependent DNA helicase RecQ, putative 0.003 0.0135 0.0897
Brugia malayi exodeoxyribonuclease III family protein 0.002 0.0037 0.0039
Mycobacterium tuberculosis Probable esterase LipL 0.0074 0.0602 0.125
Echinococcus multilocularis serotonin transporter 0.0088 0.0743 0.0743
Schistosoma mansoni mixed-lineage leukemia protein mll 0.0128 0.1163 0.1342
Onchocerca volvulus 0.0048 0.033 0.0624
Loa Loa (eye worm) hypothetical protein 0.0084 0.0707 0.0811
Echinococcus granulosus alpha 1A adrenergic receptor 0.0022 0.0055 0.0055
Onchocerca volvulus 0.0074 0.0602 0.121
Onchocerca volvulus Nuclear receptor subfamily 6 group A member 1 homolog 0.0064 0.0499 0.0989
Onchocerca volvulus 0.0059 0.0444 0.087
Trypanosoma brucei unspecified product 0.0027 0.0109 0.0357
Loa Loa (eye worm) hypothetical protein 0.0022 0.0055 0.0061
Brugia malayi Cytochrome P450 family protein 0.0088 0.0745 0.0856
Mycobacterium ulcerans sugar phosphate isomerases/epimerases 0.0041 0.0259 0.1524
Brugia malayi Cytochrome P450 family protein 0.0029 0.0126 0.0142
Schistosoma mansoni rab6-interacting 0.004 0.0247 0.0285
Trichomonas vaginalis D-aminoacylase, putative 0.0074 0.0602 0.1218
Schistosoma mansoni retinoblastoma-binding protein 4 (rbbp4) 0.0033 0.0167 0.0192
Echinococcus granulosus ecdysone induced protein 78C 0.0136 0.1256 0.1256
Mycobacterium tuberculosis Possible DNA-damage-inducible protein P DinP (DNA polymerase V) (pol IV 2) (DNA nucleotidyltransferase (DNA-directed)) 0.0039 0.0238 0.0491
Loa Loa (eye worm) hypothetical protein 0.0064 0.0499 0.0572
Leishmania major carbonic anhydrase-like protein 0.024 0.2341 0.7809
Schistosoma mansoni nAChR subunit 0.0084 0.0707 0.0816
Schistosoma mansoni regulator of G protein signaling 0.0021 0.0041 0.0047
Brugia malayi hypothetical protein 0.0433 0.4371 0.5033
Trichomonas vaginalis conserved hypothetical protein 0.0021 0.0041 0.0009
Schistosoma mansoni neuropeptide F-like receptor 0.0022 0.0055 0.0064
Onchocerca volvulus Steroid hormone receptor family member cnr14 homolog 0.0136 0.1256 0.2623
Schistosoma mansoni amine GPCR 0.0022 0.0055 0.0064
Echinococcus multilocularis Peptidase C19, ubiquitin carboxyl terminal hydrolase 2 0.0036 0.0203 0.0203
Trypanosoma brucei DNA polymerase beta thumb, putative 0.0042 0.027 0.0892
Brugia malayi Steroid receptor seven-up type 2 0.0136 0.1256 0.1445
Echinococcus granulosus orexin receptor type 2 0.0022 0.0055 0.0055
Loa Loa (eye worm) melatonin receptor type 1A 0.0022 0.0055 0.0061
Loa Loa (eye worm) hypothetical protein 0.0022 0.0055 0.0061
Mycobacterium tuberculosis Conserved protein 0.0074 0.0602 0.125
Trypanosoma brucei mitochondrial DNA polymerase beta-PAK 0.0143 0.1325 0.4417
Loa Loa (eye worm) hypothetical protein 0.0098 0.0855 0.0982
Echinococcus multilocularis somatostatin receptor 0.0022 0.0055 0.0055
Echinococcus granulosus neuropeptides capa receptor 0.0022 0.0055 0.0055
Schistosoma mansoni coup transcription factor 0.0136 0.1256 0.145
Echinococcus multilocularis Ankyrin 0.0033 0.0167 0.0167
Leishmania major ubiquitin hydrolase, putative,cysteine peptidase, Clan CA, family C19, putative 0.0036 0.0203 0.0669
Trypanosoma brucei hypothetical protein, conserved 0.0074 0.0602 0.2
Schistosoma mansoni apoferritin-2 0.0026 0.0093 0.0107
Loa Loa (eye worm) hypothetical protein 0.0055 0.0397 0.0455
Brugia malayi G-protein coupled receptor 0.0022 0.0055 0.0061
Brugia malayi hypothetical protein 0.0064 0.0499 0.0572
Brugia malayi Voltage-gated potassium channel, HERG (KCNH2)-related. C. elegans unc-103 ortholog 0.0037 0.0211 0.024
Echinococcus multilocularis NADP dependent isocitrate dehydrogenase 0.0017 0.0003 0.0003
Loa Loa (eye worm) hypothetical protein 0.0033 0.0167 0.0189
Loa Loa (eye worm) TYRA-2 protein 0.0022 0.0055 0.0061
Mycobacterium tuberculosis Probable exodeoxyribonuclease III protein XthA (exonuclease III) (EXO III) (AP endonuclease VI) 0.002 0.0037 0.0071
Loa Loa (eye worm) neuropeptide F receptor 0.0022 0.0055 0.0061
Echinococcus granulosus nicotinic acetylcholine receptor alpha subunit 0.0182 0.1739 0.1739
Loa Loa (eye worm) G-protein coupled receptor 0.0022 0.0055 0.0061
Schistosoma mansoni ferritin 0.0026 0.0093 0.0107
Mycobacterium ulcerans cytochrome P450 187A5 Cyp187A5 0.0029 0.0126 0.0609
Schistosoma mansoni serine/threonine protein kinase 0.0021 0.0041 0.0047
Loa Loa (eye worm) hypothetical protein 0.0021 0.0041 0.0044
Echinococcus multilocularis FTZ F1 nuclear receptor protein 0.0136 0.1256 0.1256
Loa Loa (eye worm) hypothetical protein 0.0026 0.0092 0.0103
Onchocerca volvulus 0.0182 0.1739 0.3664
Schistosoma mansoni carbonic anhydrase-related 0.0055 0.0397 0.0459
Mycobacterium tuberculosis Probable cytochrome P450 138 Cyp138 0.0029 0.0126 0.0256
Echinococcus multilocularis rhodopsin orphan GPCR 0.0022 0.0055 0.0055
Trichomonas vaginalis penicillin-binding protein, putative 0.0074 0.0602 0.1218
Loa Loa (eye worm) hypothetical protein 0.0021 0.0041 0.0044
Schistosoma mansoni histamine-responsive GPCR (AAF21638) 0.0022 0.0055 0.0064
Loa Loa (eye worm) hypothetical protein 0.0182 0.1739 0.2
Echinococcus granulosus ubiquitin carboxyl terminal hydrolase 8 0.0036 0.0203 0.0203
Onchocerca volvulus 0.0022 0.0055 0.0031
Loa Loa (eye worm) hypothetical protein 0.0084 0.0707 0.0811
Loa Loa (eye worm) hypothetical protein 0.0022 0.0055 0.0061
Loa Loa (eye worm) hypothetical protein 0.0022 0.0055 0.0061
Mycobacterium leprae conserved hypothetical protein 0.0041 0.0259 0.1199
Trypanosoma cruzi hypothetical protein, conserved 0.0074 0.0602 0.2
Onchocerca volvulus 0.0462 0.4676 1
Schistosoma mansoni microtubule-associated protein tau 0.0675 0.6909 0.7973
Brugia malayi Animal haem peroxidase family protein 0.0025 0.009 0.0101
Loa Loa (eye worm) hypothetical protein 0.0022 0.0055 0.0061
Onchocerca volvulus 0.0084 0.0707 0.1437
Loa Loa (eye worm) nicotinic acetylcholine receptor non-alpha subunit 0.0182 0.1739 0.2
Echinococcus granulosus Mitotic checkpoint protein PRCC C terminal 0.013 0.1192 0.1192
Echinococcus multilocularis glycine receptor subunit alpha 1 0.0182 0.1739 0.1739
Echinococcus granulosus neuropeptide Y receptor 0.0022 0.0055 0.0055
Schistosoma mansoni axis inhibition protein axin 0.0021 0.0041 0.0047
Onchocerca volvulus 0.0025 0.009 0.0106
Trypanosoma brucei mitochondrial DNA polymerase beta 0.0302 0.2997 1
Schistosoma mansoni nuclear receptor 0.0064 0.0499 0.0576
Schistosoma mansoni regulator of G protein signaling 3 rgs3 0.0021 0.0041 0.0047
Toxoplasma gondii ABC1 family protein 0.0074 0.0602 0.4054
Onchocerca volvulus Putative nachr subunit 0.0182 0.1739 0.3664
Echinococcus granulosus geminin 0.0528 0.5369 0.5369
Mycobacterium ulcerans cytochrome P450 144A4 Cyp144A4 0.0029 0.0126 0.0609
Brugia malayi GCC2 and GCC3 family protein 0.0021 0.0043 0.0047
Loa Loa (eye worm) animal heme peroxidase 0.0025 0.009 0.0101
Mycobacterium tuberculosis Cytochrome P450 121 Cyp121 0.0029 0.0126 0.0256
Echinococcus multilocularis glycine receptor subunit beta 0.0182 0.1739 0.1739
Echinococcus granulosus microtubule associated protein 2 0.0675 0.6909 0.6909
Schistosoma mansoni cpg binding protein 0.0062 0.048 0.0553
Brugia malayi Dopamine receptor protein 1, putative (partial) 0.0022 0.0055 0.0061
Brugia malayi larval opioid receptor 0.0022 0.0055 0.0061
Schistosoma mansoni nuclear receptor nhr-48 0.0064 0.0499 0.0576
Loa Loa (eye worm) RNA recognition domain-containing protein domain-containing protein 0.0068 0.0542 0.0622
Leishmania major mitochondrial DNA polymerase beta 0.0302 0.2997 1
Echinococcus multilocularis carbonic anhydrase 0.0055 0.0397 0.0397
Loa Loa (eye worm) voltage and ligand gated potassium channel 0.0037 0.0211 0.024
Giardia lamblia Endonuclease/Exonuclease/phosphatase 0.002 0.0037 0.1026
Mycobacterium ulcerans cytochrome P450 136A2 Cyp136A2 0.0029 0.0126 0.0609
Schistosoma mansoni ferritin 0.0026 0.0093 0.0107
Brugia malayi Uncoordinated protein 44 0.0032 0.0164 0.0186
Echinococcus multilocularis Cys loop ligand gated ion channel subunit 0.0084 0.0707 0.0707
Onchocerca volvulus 0.0064 0.0499 0.0989
Brugia malayi beta-lactamase 0.0074 0.0602 0.069
Schistosoma mansoni neuropeptide f receptor 76f 0.0022 0.0055 0.0064
Brugia malayi Cytochrome P450 family protein 0.0056 0.0408 0.0466
Schistosoma mansoni aldehyde dehydrogenase 0.0059 0.0447 0.0516
Schistosoma mansoni Cys-loop ligand gated ion channel subunit 0.0182 0.1739 0.2007
Trichomonas vaginalis soluble guanylate cyclase gcy, putative 0.0026 0.0097 0.0129
Schistosoma mansoni neuropeptide F-like receptor 0.0022 0.0055 0.0064
Echinococcus granulosus histone lysine N methyltransferase MLL3 0.002 0.0038 0.0038
Loa Loa (eye worm) hypothetical protein 0.0033 0.0167 0.0189
Trypanosoma cruzi PAS-domain containing phosphoglycerate kinase, putative 0.0026 0.0097 0.0314
Loa Loa (eye worm) nuclear hormone receptor-like 1 0.0072 0.058 0.0666
Echinococcus granulosus glycine receptor subunit beta 0.0182 0.1739 0.1739
Echinococcus granulosus neuropeptide receptor A26 0.0969 1 1
Schistosoma mansoni voltage-gated potassium channel 0.004 0.0247 0.0285
Toxoplasma gondii aldehyde dehydrogenase 0.0059 0.0447 0.3006
Brugia malayi Nuclear hormone receptor family member nhr-41 0.0136 0.1256 0.1445
Loa Loa (eye worm) hypothetical protein 0.0022 0.0055 0.0061
Loa Loa (eye worm) hypothetical protein 0.0022 0.0055 0.0061
Echinococcus granulosus glycine receptor subunit alpha 1 0.0182 0.1739 0.1739
Echinococcus granulosus fatty acid amide hydrolase 1 0.0098 0.0858 0.0858
Brugia malayi Eukaryotic-type carbonic anhydrase family protein 0.0055 0.0397 0.0455
Loa Loa (eye worm) hypothetical protein 0.0084 0.0707 0.0811
Schistosoma mansoni biogenic amine receptor 0.0022 0.0055 0.0064
Echinococcus granulosus potassium voltage gated channel subfamily H 0.0037 0.0211 0.0211
Loa Loa (eye worm) LGC-31 protein 0.0182 0.1739 0.2
Brugia malayi Hypothetical 52.5 kDa protein ZK945.1 in chromosome II, putative 0.0074 0.0602 0.069
Treponema pallidum sodium- and chloride- dependent transporter 0.0088 0.0743 1
Onchocerca volvulus 0.0064 0.0499 0.0989
Loa Loa (eye worm) ATP-dependent DNA helicase 0.0018 0.0014 0.0013
Trypanosoma cruzi ubiquitin carboxyl-terminal hydrolase, putative 0.0036 0.0203 0.0669
Schistosoma mansoni nuclear receptor 0.0064 0.0499 0.0576
Brugia malayi regulator of G-protein signaling egl-10 0.0021 0.0041 0.0044
Echinococcus multilocularis neuropeptides capa receptor 0.0022 0.0055 0.0055
Echinococcus multilocularis survival motor neuron protein 1 0.0237 0.2308 0.2308
Echinococcus multilocularis g protein coupled receptor 0.0022 0.0055 0.0055
Schistosoma mansoni blooms syndrome DNA helicase 0.0035 0.0188 0.0216
Brugia malayi Nuclear hormone receptor E75 0.0064 0.0499 0.0572
Schistosoma mansoni tar DNA-binding protein 0.0068 0.0542 0.0626
Schistosoma mansoni biogenic amine (octopamine/dopamine) receptor 0.0022 0.0055 0.0064
Echinococcus multilocularis fmrfamide receptor 0.0022 0.0055 0.0055
Echinococcus granulosus fatty acid amide hydrolase 1 0.0098 0.0858 0.0858
Mycobacterium ulcerans cytochrome P450 150A6 Cyp150A6 0.0029 0.0126 0.0609
Loa Loa (eye worm) hypothetical protein 0.0021 0.0041 0.0044
Echinococcus multilocularis NADP dependent isocitrate dehydrogenase 0.0017 0.0003 0.0003
Trypanosoma cruzi ATP-dependent DEAD/H DNA helicase recQ, putative 0.0023 0.007 0.0224
Onchocerca volvulus 0.0022 0.0055 0.0031
Plasmodium falciparum AP endonuclease (DNA-[apurinic or apyrimidinic site] lyase), putative 0.002 0.0037 0.0231
Brugia malayi Metabotropic glutamate receptor precursor. 0.0033 0.0167 0.0189
Loa Loa (eye worm) cytochrome P450 family protein 0.0056 0.0408 0.0466
Echinococcus granulosus ubiquitin specific protease 41 0.0036 0.0203 0.0203
Schistosoma mansoni amine GPCR 0.0022 0.0055 0.0064
Mycobacterium ulcerans aldehyde dehydrogenase 0.0059 0.0447 0.2811
Echinococcus multilocularis axis inhibition protein axin 0.0021 0.0041 0.0041
Leishmania major cytochrome p450-like protein 0.0056 0.0408 0.1352
Trypanosoma cruzi STE/STE11 serine/threonine-protein kinase, putative 0.0026 0.0097 0.0314
Leishmania major aldehyde dehydrogenase, mitochondrial precursor 0.0059 0.0447 0.1483
Plasmodium vivax apurinic/apyrimidinic endonuclease Apn1, putative 0.0158 0.148 1
Echinococcus granulosus hypothetical protein 0.0689 0.7058 0.7058
Echinococcus granulosus hepatocyte nuclear factor 4 alpha 0.0136 0.1256 0.1256
Toxoplasma gondii hypothetical protein 0.0049 0.0335 0.2251
Loa Loa (eye worm) hypothetical protein 0.0064 0.0499 0.0572
Schistosoma mansoni fatty-acid amide hydrolase 0.0098 0.0858 0.099
Brugia malayi Hypothetical 29.7 kDa protein C05D11.5 in chromosome III 0.0041 0.0259 0.0295
Brugia malayi Hypothetical glycine receptor like protein T20B12.9 in chromosome III 0.0182 0.1739 0.2
Loa Loa (eye worm) eukaryotic-type carbonic anhydrase 0.024 0.2341 0.2694
Echinococcus multilocularis DNA (apurinic or apyrimidinic site) lyase 0.002 0.0037 0.0037
Loa Loa (eye worm) hypothetical protein 0.0182 0.1739 0.2
Brugia malayi Nuclear hormone receptor family member nhr-25 0.0136 0.1256 0.1445
Brugia malayi Neurotransmitter-gated ion-channel ligand binding domain containing protein 0.0182 0.1739 0.2
Echinococcus granulosus Basic leucine zipper bZIP transcription factor 0.0276 0.2723 0.2723
Echinococcus multilocularis GPCR, family 2 0.0032 0.0164 0.0164
Brugia malayi regulator of G-protein signaling rgs-7 0.0021 0.0041 0.0044
Plasmodium falciparum LCCL domain-containing protein 0.004 0.0247 0.1655
Brugia malayi metabotropic glutamate receptor subtype 5a (mGluR5a), putative 0.0021 0.0041 0.0044
Schistosoma mansoni nuclear hormone receptor nor-1/nor-2 0.0136 0.1256 0.145
Onchocerca volvulus 0.0022 0.0055 0.0031
Trypanosoma cruzi cytochrome P450, putative 0.0056 0.0408 0.1352
Echinococcus granulosus rhodopsin orphan GPCR 0.0022 0.0055 0.0055
Brugia malayi PXA domain containing protein 0.0021 0.0041 0.0044
Schistosoma mansoni zinc finger protein 0.0064 0.0499 0.0576
Echinococcus multilocularis sex peptide receptor 0.0022 0.0055 0.0055
Echinococcus multilocularis regulator of G protein signaling 7 0.0021 0.0041 0.0041
Echinococcus multilocularis G protein coupled receptor 139 0.0022 0.0055 0.0055
Trypanosoma cruzi DNA polymerase eta, putative 0.0039 0.0238 0.0787
Loa Loa (eye worm) glutamate-gated chloride channel alpha3A subunit 0.0084 0.0707 0.0811
Trypanosoma brucei DNA polymerase kappa, putative 0.0039 0.0238 0.0787
Brugia malayi Peroxidasin 0.0025 0.009 0.0101
Schistosoma mansoni single-minded 0.01 0.0875 0.101
Loa Loa (eye worm) hypothetical protein 0.0032 0.016 0.0181
Trichomonas vaginalis set domain proteins, putative 0.0462 0.4673 1
Leishmania major PAS-domain containing phosphoglycerate kinase, putative 0.0026 0.0097 0.0314
Brugia malayi putative neuropeptide receptor NPR1 0.0022 0.0055 0.0061
Brugia malayi Serotonin receptor 0.0467 0.4724 0.5439
Schistosoma mansoni neurotransmitter gated ion channel 0.0084 0.0707 0.0816
Trypanosoma brucei DNA polymerase kappa, putative 0.0039 0.0238 0.0787
Loa Loa (eye worm) hypothetical protein 0.0084 0.0707 0.0811
Onchocerca volvulus 0.0022 0.0055 0.0031
Echinococcus multilocularis 0.0029 0.0126 0.0126
Echinococcus multilocularis pyroglutamylated rfamide peptide receptor 0.0022 0.0055 0.0055
Brugia malayi Neurotransmitter-gated ion-channel ligand binding domain containing protein 0.0084 0.0707 0.0811
Leishmania major ATP-dependent DEAD/H DNA helicase recQ, putative 0.0023 0.007 0.0224
Schistosoma mansoni lamin 0.0026 0.0097 0.0112
Loa Loa (eye worm) nuclear receptor nhr-7B 0.0064 0.0499 0.0572
Brugia malayi ImpB/MucB/SamB family protein 0.0039 0.0238 0.0271
Schistosoma mansoni cpg binding protein 0.0059 0.0444 0.0513
Trypanosoma cruzi DNA polymerase beta thumb, putative 0.0042 0.027 0.0892
Echinococcus granulosus 5'partial|histone lysine N methyltransferase SETDB2 0.0056 0.041 0.041
Schistosoma mansoni lipoxygenase 0.004 0.0247 0.0285
Trichomonas vaginalis Clan CA, family C19, ubiquitin hydrolase-like cysteine peptidase 0.0036 0.0203 0.0359
Echinococcus multilocularis FTZ F1 alpha 0.0136 0.1256 0.1256
Loa Loa (eye worm) hypothetical protein 0.0088 0.0743 0.0853
Echinococcus multilocularis ubiquitin carboxyl terminal hydrolase 8 0.0036 0.0203 0.0203
Echinococcus granulosus ATP dependent DNA helicase Q1 0.0018 0.0014 0.0014
Loa Loa (eye worm) hypothetical protein 0.0182 0.1739 0.2
Loa Loa (eye worm) ImpB/MucB/SamB family protein 0.0039 0.0238 0.0271
Trichomonas vaginalis adenylate and guanylate cyclases, putative 0.0026 0.0097 0.0129
Toxoplasma gondii histone lysine methyltransferase SET1 0.0114 0.1022 0.6898
Echinococcus multilocularis neuronal acetylcholine receptor subunit alpha 4 0.0182 0.1739 0.1739
Loa Loa (eye worm) G-protein coupled receptor 0.0022 0.0055 0.0061
Loa Loa (eye worm) hypothetical protein 0.0759 0.7799 0.8982
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0022 0.0055 0.0064
Echinococcus multilocularis nuclear receptor subfamily 1 group D 0.0072 0.058 0.058
Schistosoma mansoni Cys-loop ligand gated ion channel subunit 0.0182 0.1739 0.2007
Echinococcus granulosus terminal deoxycytidyl transferase rev1 0.0039 0.0238 0.0238
Echinococcus multilocularis lipoxygenase domain containing protein 0.004 0.0247 0.0247
Echinococcus multilocularis rhodopsin orphan GPCR 0.0022 0.0055 0.0055
Plasmodium vivax hypothetical protein, conserved 0.0074 0.0602 0.4054
Loa Loa (eye worm) blistered cuticle protein 3 0.0025 0.009 0.0101
Mycobacterium tuberculosis Probable cytochrome P450 136 Cyp136 0.0029 0.0126 0.0256
Loa Loa (eye worm) DR-78 0.0064 0.0499 0.0572
Loa Loa (eye worm) hypothetical protein 0.0022 0.0055 0.0061
Echinococcus granulosus nicotinic acetylcholine receptor a11 subunit 0.0182 0.1739 0.1739
Mycobacterium ulcerans fusion of enoyl-CoA hydratase, EchA21 and lipase, LipE 0.0074 0.0602 0.3873
Echinococcus multilocularis Basic leucine zipper (bZIP) transcription 0.0112 0.1 0.1
Echinococcus multilocularis rhodopsin orphan GPCR 0.0022 0.0055 0.0055
Echinococcus multilocularis GPCR, family 3, C terminal 0.0021 0.0041 0.0041
Echinococcus granulosus tar DNA binding protein 0.0068 0.0542 0.0542
Mycobacterium tuberculosis Cytochrome P450 51 Cyp51 (CYPL1) (P450-L1A1) (sterol 14-alpha demethylase) (lanosterol 14-alpha demethylase) (P450-14DM) 0.0029 0.0126 0.0256
Brugia malayi Regulator of G protein signaling domain containing protein 0.0021 0.0041 0.0044
Brugia malayi Serotonin/octopamine receptor family protein 7 0.0022 0.0055 0.0061
Mycobacterium tuberculosis Probable lipase LipD 0.0074 0.0602 0.125
Brugia malayi Neurotransmitter-gated ion-channel transmembrane region family protein 0.0182 0.1739 0.2
Brugia malayi metabotropic glutamate receptor type 2 0.0033 0.0167 0.0189
Leishmania major protein kinase, putative 0.0031 0.0148 0.0485
Mycobacterium tuberculosis Probable cytochrome P450 140 Cyp140 0.0029 0.0126 0.0256
Echinococcus granulosus FTZ F1 nuclear receptor protein 0.0136 0.1256 0.1256
Loa Loa (eye worm) hypothetical protein 0.0022 0.0055 0.0061
Schistosoma mansoni amine GPCR 0.0022 0.0055 0.0064
Echinococcus granulosus diuretic hormone 44 receptor GPRdih2 0.0032 0.0164 0.0164
Loa Loa (eye worm) hypothetical protein 0.0022 0.0055 0.0061
Trypanosoma brucei DNA polymerase kappa, putative 0.0027 0.0109 0.0357
Loa Loa (eye worm) hypothetical protein 0.0064 0.0499 0.0572
Brugia malayi Receptor family ligand binding region containing protein 0.0144 0.1336 0.1537
Mycobacterium tuberculosis Conserved protein 0.0074 0.0602 0.125
Schistosoma mansoni nuclear hormone receptor 0.0136 0.1256 0.145
Loa Loa (eye worm) G protein signaling regulator EGL-10 0.0021 0.0041 0.0044
Trypanosoma cruzi DNA polymerase kappa, putative 0.0039 0.0238 0.0787
Plasmodium vivax multidomain scavenger receptor, putative 0.004 0.0247 0.1655
Trypanosoma brucei DNA polymerase IV, putative 0.0039 0.0238 0.0787
Brugia malayi Protein kinase domain containing protein 0.0032 0.0164 0.0186
Echinococcus granulosus histone lysine methyltransferase setb 0.0059 0.0446 0.0446
Loa Loa (eye worm) hypothetical protein 0.0182 0.1739 0.2
Loa Loa (eye worm) hypothetical protein 0.0084 0.0707 0.0811
Echinococcus multilocularis fatty acid amide hydrolase 1 0.0098 0.0858 0.0858
Schistosoma mansoni hypothetical protein 0.0112 0.1 0.1154
Echinococcus multilocularis expressed protein 0.0403 0.4059 0.4059
Echinococcus granulosus nuclear receptor 2DBD gamma 0.0136 0.1256 0.1256
Echinococcus multilocularis neuropeptide Y receptor 0.0022 0.0055 0.0055
Loa Loa (eye worm) hypothetical protein 0.0843 0.8682 1
Brugia malayi hypothetical protein 0.004 0.0247 0.0282
Onchocerca volvulus Peroxidasin homolog 0.0025 0.009 0.0106
Onchocerca volvulus Peroxidase homolog 0.0025 0.009 0.0106
Brugia malayi Animal haem peroxidase family protein 0.0025 0.009 0.0101
Onchocerca volvulus 0.0022 0.0055 0.0031
Brugia malayi steroid hormone receptor 0.0136 0.1256 0.1445
Echinococcus granulosus lamin dm0 0.0026 0.0097 0.0097
Brugia malayi Nuclear hormone receptor E75 0.0064 0.0499 0.0572
Schistosoma mansoni nAChR subunit (ShAR1-alpha-like) 0.0182 0.1739 0.2007
Loa Loa (eye worm) hypothetical protein 0.0022 0.0055 0.0061
Trichomonas vaginalis guanylate cyclase, putative 0.0026 0.0097 0.0129
Mycobacterium tuberculosis Probable esterase/lipase LipP 0.0074 0.0602 0.125
Trypanosoma brucei carbonic anhydrase-like protein 0.024 0.2341 0.7809
Schistosoma mansoni retinoid-x-receptor (RXR) 0.0136 0.1256 0.145
Trypanosoma brucei DNA polymerase kappa, putative 0.0039 0.0238 0.0787
Giardia lamblia Ubiquitin carboxyl-terminal hydrolase 4 0.0036 0.0203 0.8434
Mycobacterium ulcerans putative regulatory protein 0.0074 0.0602 0.3873
Trypanosoma brucei unspecified product 0.0027 0.0109 0.0357
Schistosoma mansoni hypothetical protein 0.0528 0.5369 0.6197
Brugia malayi gamma-aminobutyric-acid receptor beta subunit precursor 0.0843 0.8682 1
Echinococcus granulosus netrin receptor unc 5 0.0032 0.0164 0.0164
Schistosoma mansoni nAChR subunit 0.0182 0.1739 0.2007
Mycobacterium leprae Probable lipase LipE 0.0074 0.0602 0.3668
Mycobacterium ulcerans DNA polymerase IV 0.0039 0.0238 0.1381
Brugia malayi nuclear hormone receptor family member nhr-6 0.0064 0.0499 0.0572
Echinococcus granulosus acetylcholine receptor subunit beta 1 0.0182 0.1739 0.1739
Schistosoma mansoni transcription factor LCR-F1 0.0112 0.1 0.1154
Mycobacterium ulcerans cytochrome P450 126A3 Cyp126A3 0.0029 0.0126 0.0609
Mycobacterium tuberculosis Possible conserved lipoprotein LpqK 0.0074 0.0602 0.125
Echinococcus multilocularis lipoxygenase domain containing protein 0.004 0.0247 0.0247
Schistosoma mansoni hypothetical protein 0.0842 0.8665 1
Brugia malayi ATP-dependent DNA helicase, RecQ family protein 0.0018 0.0014 0.0013
Schistosoma mansoni peptide (FMRFamide/neurokinin-3)-like receptor 0.0022 0.0055 0.0064
Onchocerca volvulus Dual oxidase homolog 0.0025 0.009 0.0106
Mycobacterium ulcerans cytochrome P450 185A4 Cyp185A4 0.0056 0.0408 0.2542
Loa Loa (eye worm) beta-lactamase 0.0074 0.0602 0.069
Loa Loa (eye worm) hypothetical protein 0.007 0.056 0.0642
Echinococcus granulosus rhodopsin orphan GPCR 0.0022 0.0055 0.0055
Schistosoma mansoni neuropeptide receptor 0.0022 0.0055 0.0064
Echinococcus granulosus carbonic anhydrase 0.0055 0.0397 0.0397
Loa Loa (eye worm) hypothetical protein 0.0136 0.1256 0.1445
Loa Loa (eye worm) hypothetical protein 0.0084 0.0707 0.0811
Brugia malayi ImpB/MucB/SamB family protein 0.0039 0.0238 0.0271
Loa Loa (eye worm) nuclear Hormone Receptor family member 0.0136 0.1256 0.1445
Echinococcus multilocularis rhodopsin orphan GPCR 0.0022 0.0055 0.0055
Brugia malayi putative neuropeptide receptor 0.0022 0.0055 0.0061
Onchocerca volvulus Neuropeptide F receptor homolog 0.0022 0.0055 0.0031
Brugia malayi nuclear receptor NHR-88 0.0136 0.1256 0.1445
Entamoeba histolytica hypothetical protein 0.0098 0.0855 0.8498
Echinococcus granulosus rhodopsin orphan GPCR 0.0022 0.0055 0.0055
Echinococcus multilocularis tumor protein p63 0.0365 0.3658 0.3658
Brugia malayi hypothetical protein 0.0084 0.0707 0.0811
Brugia malayi nuclear receptor NHR-67 0.0064 0.0499 0.0572
Loa Loa (eye worm) hypothetical protein 0.0055 0.0397 0.0455
Onchocerca volvulus 0.0022 0.0055 0.0031
Loa Loa (eye worm) hypothetical protein 0.0022 0.0055 0.0061
Brugia malayi glutamate-gated chloride channel alpha3A subunit, putative 0.0098 0.0855 0.0982
Brugia malayi Dopamine receptor protein 2 0.0022 0.0055 0.0061
Mycobacterium ulcerans lipase LipD 0.0074 0.0602 0.3873
Trypanosoma cruzi mitochondrial DNA polymerase beta-PAK, putative 0.0042 0.027 0.0892
Echinococcus granulosus neuropeptide receptor 0.0022 0.0055 0.0055
Loa Loa (eye worm) metabotropic GABA-B receptor subtype 2 0.029 0.2873 0.3307
Loa Loa (eye worm) exodeoxyribonuclease III family protein 0.002 0.0037 0.0039
Schistosoma mansoni survival motor neuron protein 0.0048 0.033 0.0381
Schistosoma mansoni NADP-specific isocitrate dehydrogenase 0.0017 0.0003 0.0003
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0022 0.0055 0.0064
Echinococcus granulosus somatostatin receptor 0.0022 0.0055 0.0055
Trypanosoma brucei apurinic/apyrimidinic endonuclease, putative 0.002 0.0037 0.0114
Schistosoma mansoni amine GPCR 0.0022 0.0055 0.0064
Schistosoma mansoni RAR-like nuclear receptor 0.0136 0.1256 0.145
Echinococcus multilocularis potassium voltage gated channel subfamily H 0.0037 0.0211 0.0211
Echinococcus multilocularis regulator of G protein signaling 3 0.0021 0.0041 0.0041
Leishmania major apurinic/apyrimidinic endonuclease-redox protein 0.002 0.0037 0.0114
Echinococcus granulosus retinoic acid receptor rxr beta a 0.0331 0.33 0.33
Brugia malayi nicotinic acetylcholine receptor alpha subunit, putative 0.0182 0.1739 0.2
Onchocerca volvulus 0.0059 0.0446 0.0875
Trichomonas vaginalis adenylate and guanylate cyclases, putative 0.0026 0.0097 0.0129
Echinococcus multilocularis conserved hypothetical protein 0.0667 0.6826 0.6826
Onchocerca volvulus Chorion peroxidase homolog 0.0025 0.009 0.0106
Trypanosoma cruzi STE/STE11 serine/threonine-protein kinase, putative 0.0026 0.0097 0.0314
Brugia malayi GnHR receptor homolog 0.0022 0.0055 0.0061
Echinococcus granulosus nuclear factor of activated T cells 5 0.0166 0.1567 0.1567
Schistosoma mansoni thyroid hormone receptor 0.0267 0.2625 0.303
Echinococcus multilocularis carbonic anhydrase 0.0055 0.0397 0.0397
Trichomonas vaginalis DNA helicase recq, putative 0.0023 0.007 0.0071
Echinococcus multilocularis biogenic amine (5HT) receptor 0.0022 0.0055 0.0055
Loa Loa (eye worm) animal heme peroxidase 0.0025 0.009 0.0101
Brugia malayi excitatory GABA receptor EXP-1A 0.0182 0.1739 0.2
Loa Loa (eye worm) intermediate filament protein 0.0026 0.0097 0.0109
Brugia malayi DNA-(Apurinic or apyrimidinic site) lyase 0.0158 0.148 0.1702
Echinococcus multilocularis transfer RNA-Lys 0.0074 0.0602 0.0602
Echinococcus multilocularis g-protein coupled receptor 0.0022 0.0055 0.0055
Echinococcus multilocularis netrin receptor unc 5 0.0032 0.0164 0.0164
Brugia malayi hypothetical protein 0.0022 0.0055 0.0061
Mycobacterium ulcerans cytochrome P450 140A5 Cyp140A5 0.0029 0.0126 0.0609
Echinococcus multilocularis nAChR subunit 0.0182 0.1739 0.1739
Echinococcus granulosus death domain containing protein 0.0032 0.0164 0.0164
Echinococcus multilocularis cadherin EGF LAG seven pass G type receptor 0.0032 0.0164 0.0164
Onchocerca volvulus 0.0217 0.21 0.4443
Echinococcus multilocularis G-protein coupled receptor, putative 0.0022 0.0055 0.0055
Mycobacterium ulcerans cytochrome P450 143A4 Cyp143A4 0.0029 0.0126 0.0609
Trypanosoma brucei ATP-dependent DEAD/H DNA helicase recQ, putative 0.0023 0.007 0.0224
Loa Loa (eye worm) hypothetical protein 0.0022 0.0055 0.0061
Echinococcus granulosus A kinase anchor protein 10 mitochondrial 0.0021 0.0041 0.0041
Schistosoma mansoni metabotropic glutamate receptor 0.0033 0.0167 0.0193
Schistosoma mansoni hypothetical protein 0.0032 0.0164 0.0189
Loa Loa (eye worm) hypothetical protein 0.0022 0.0055 0.0061
Loa Loa (eye worm) hypothetical protein 0.0072 0.058 0.0666
Echinococcus multilocularis NADP dependent isocitrate dehydrogenase 0.0017 0.0003 0.0003
Echinococcus multilocularis Polycystic kidney disease protein 0.004 0.0247 0.0247
Brugia malayi bHLH-PAS transcription factor 0.0074 0.0602 0.069
Toxoplasma gondii histone lysine methyltransferase SET/SUV39 0.0059 0.0446 0.3003
Echinococcus granulosus thyroid hormone receptor alpha 0.0064 0.0499 0.0499
Mycobacterium tuberculosis Probable hydrolase 0.0074 0.0602 0.125
Echinococcus multilocularis hepatocyte nuclear factor 4 alpha 0.0136 0.1256 0.1256
Loa Loa (eye worm) hypothetical protein 0.0022 0.0055 0.0061
Schistosoma mansoni biogenic amine (dopamine) receptor 0.0022 0.0055 0.0064
Echinococcus granulosus Peptidase C19 ubiquitin carboxyl terminal hydrolase 2 0.0036 0.0203 0.0203
Schistosoma mansoni hypothetical protein 0.0022 0.0055 0.0064
Loa Loa (eye worm) hypothetical protein 0.0025 0.009 0.0101
Chlamydia trachomatis endonuclease IV 0.0158 0.148 1
Brugia malayi G protein-coupled receptor F59B2.13 0.0022 0.0055 0.0061
Trichomonas vaginalis adenylate and guanylate cyclases, putative 0.0026 0.0097 0.0129
Loa Loa (eye worm) hypothetical protein 0.0103 0.0901 0.1035
Mycobacterium ulcerans cytochrome P450 105Q4 Cyp105Q4 0.0029 0.0126 0.0609
Echinococcus granulosus g protein coupled receptor 0.0022 0.0055 0.0055
Mycobacterium tuberculosis Probable cytochrome P450 132 Cyp132 0.0029 0.0126 0.0256
Echinococcus multilocularis neuropeptide receptor A26 0.0969 1 1
Leishmania major cytochrome p450-like protein 0.0029 0.0126 0.041
Onchocerca volvulus 0.0098 0.0855 0.1757
Schistosoma mansoni opsin-like receptor 0.0022 0.0055 0.0064
Loa Loa (eye worm) hypothetical protein 0.0022 0.0055 0.0061
Echinococcus granulosus GPCR family 3 C terminal 0.0021 0.0041 0.0041
Brugia malayi Animal haem peroxidase family protein 0.0025 0.009 0.0101
Trichomonas vaginalis D-aminoacylase, putative 0.0074 0.0602 0.1218
Echinococcus multilocularis regulator of G protein signaling 0.0021 0.0041 0.0041
Mycobacterium leprae PROBABLE ENDONUCLEASE IV END (ENDODEOXYRIBONUCLEASE IV) (APURINASE) 0.0158 0.148 1
Brugia malayi Neuronal acetylcholine receptor protein, alpha-2 chain precursor 0.0084 0.0707 0.0811
Onchocerca volvulus 0.0022 0.0055 0.0031
Echinococcus granulosus COUP TF:Svp nuclear hormone receptor 0.0136 0.1256 0.1256
Brugia malayi hypothetical protein 0.0022 0.0055 0.0061
Trichomonas vaginalis esterase, putative 0.0074 0.0602 0.1218
Echinococcus multilocularis serotonin receptor 0.0022 0.0055 0.0055
Echinococcus multilocularis peptide (allatostatin:somatostatin) 0.0022 0.0055 0.0055
Schistosoma mansoni hypothetical protein 0.0021 0.0041 0.0047
Mycobacterium tuberculosis Bacterioferritin BfrB 0.0026 0.0093 0.0188
Schistosoma mansoni family S12 unassigned peptidase (S12 family) 0.0074 0.0602 0.0694
Echinococcus multilocularis expressed protein 0.0026 0.0093 0.0093
Mycobacterium tuberculosis Probable lipase LipE 0.0074 0.0602 0.125
Echinococcus granulosus dro:myosuppressin receptor 0.0022 0.0055 0.0055
Loa Loa (eye worm) hypothetical protein 0.0182 0.1739 0.2
Loa Loa (eye worm) glutamate-gated chloride channel alpha3A subunit 0.0182 0.1739 0.2
Loa Loa (eye worm) steroid hormone receptor 0.0136 0.1256 0.1445
Loa Loa (eye worm) G-protein-linked acetylcholine receptor protein 2 0.0022 0.0055 0.0061
Schistosoma mansoni DNA helicase recq5 0.0018 0.0014 0.0016
Echinococcus granulosus arachidonate 5 lipoxygenase 0.0113 0.101 0.101
Loa Loa (eye worm) hypothetical protein 0.0025 0.009 0.0101
Trypanosoma brucei DNA polymerase kappa, putative 0.0027 0.0109 0.0357
Loa Loa (eye worm) hypothetical protein 0.0084 0.0707 0.0811
Mycobacterium tuberculosis Conserved hypothetical protein 0.0159 0.1495 0.3114
Trypanosoma cruzi mitochondrial DNA polymerase beta, putative 0.0302 0.2997 1
Echinococcus multilocularis A kinase anchor protein 10, mitochondrial 0.0021 0.0041 0.0041
Schistosoma mansoni nAChR subunit 0.0182 0.1739 0.2007
Echinococcus multilocularis G protein coupled 5 hydroxytryptamine receptor 0.0022 0.0055 0.0055
Loa Loa (eye worm) nuclear receptor NHR-67 0.0064 0.0499 0.0572
Schistosoma mansoni adenoreceptor 0.0022 0.0055 0.0064
Brugia malayi Unidentified vitellogenin-linked transcript protein 6, putative 0.0022 0.0055 0.0061
Brugia malayi G protein-coupled receptor 0.0022 0.0055 0.0061
Echinococcus granulosus gamma aminobutyric acid receptor subunit 0.0084 0.0707 0.0707
Loa Loa (eye worm) hypothetical protein 0.0064 0.0499 0.0572
Loa Loa (eye worm) glutamate receptor 0.0021 0.0041 0.0044
Echinococcus multilocularis nicotinic acetylcholine receptor alpha subunit 0.0182 0.1739 0.1739
Echinococcus granulosus Regulator of G protein signaling 20 0.0021 0.0041 0.0041
Brugia malayi hypothetical protein 0.004 0.0247 0.0282
Trypanosoma cruzi hypothetical protein, conserved 0.0074 0.0602 0.2
Schistosoma mansoni retinoid-x-receptor (RXR) 0.0072 0.058 0.067
Trichomonas vaginalis ferritin, putative 0.0026 0.0093 0.012
Schistosoma mansoni ancient conserved domain protein 2 (cyclin m2) 0.0022 0.0055 0.0064
Mycobacterium ulcerans cytochrome P450 108B4 Cyp108B4 0.0029 0.0126 0.0609
Loa Loa (eye worm) hypothetical protein 0.0098 0.0855 0.0982
Brugia malayi Neurotransmitter-gated ion-channel transmembrane region family protein 0.0098 0.0855 0.0982
Brugia malayi AKH receptor 0.0022 0.0055 0.0061
Echinococcus granulosus biogenic amine 5HT receptor 0.0022 0.0055 0.0055
Mycobacterium tuberculosis Probable bacterioferritin BfrA 0.0026 0.0093 0.0188
Trypanosoma cruzi apurinic/apyrimidinic endonuclease, putative 0.002 0.0037 0.0114
Mycobacterium ulcerans hypothetical protein 0.0041 0.0259 0.1524
Echinococcus multilocularis rhodopsin orphan GPCR 0.0022 0.0055 0.0055
Loa Loa (eye worm) hypothetical protein 0.0022 0.0055 0.0061
Schistosoma mansoni amine GPCR 0.0022 0.0055 0.0064
Onchocerca volvulus 0.0022 0.0055 0.0031
Schistosoma mansoni serine/threonine protein kinase 0.0021 0.0041 0.0047
Echinococcus multilocularis tar DNA binding protein 0.0068 0.0542 0.0542
Trypanosoma cruzi DNA polymerase kappa, putative 0.0039 0.0238 0.0787
Loa Loa (eye worm) nuclear hormone receptor family member nhr-1 0.0136 0.1256 0.1445
Loa Loa (eye worm) hypothetical protein 0.0074 0.0602 0.069
Onchocerca volvulus 0.0022 0.0055 0.0031
Schistosoma mansoni histone-lysine n-methyltransferase setb1 0.0059 0.0446 0.0515
Trypanosoma brucei DNA polymerase kappa, putative 0.0039 0.0238 0.0787
Loa Loa (eye worm) hypothetical protein 0.0182 0.1739 0.2
Trypanosoma cruzi cytochrome P450, putative 0.0056 0.0408 0.1352
Loa Loa (eye worm) hypothetical protein 0.0838 0.863 0.994
Loa Loa (eye worm) hypothetical protein 0.0098 0.0855 0.0982
Leishmania major DNA polymerase kappa, putative,DNA polymerase IV, putative 0.0039 0.0238 0.0787
Brugia malayi Ligand-binding domain of nuclear hormone receptor family protein 0.0136 0.1256 0.1445
Mycobacterium tuberculosis Probable cytochrome P450 141 Cyp141 0.0029 0.0126 0.0256
Loa Loa (eye worm) nuclear hormone receptor family member nhr-41 0.0136 0.1256 0.1445
Brugia malayi Nuclear hormone receptor-like 1 0.0072 0.058 0.0666
Echinococcus granulosus cadherin EGF LAG seven pass G type receptor 0.0032 0.0164 0.0164
Loa Loa (eye worm) hypothetical protein 0.0072 0.058 0.0666
Echinococcus multilocularis jun protein 0.0276 0.2723 0.2723
Mycobacterium ulcerans hypothetical protein 0.0159 0.1495 1
Brugia malayi Nuclear hormone receptor family member nhr-40 0.0136 0.1256 0.1445
Brugia malayi neuropeptide F receptor 0.0022 0.0055 0.0061
Loa Loa (eye worm) hypothetical protein 0.0336 0.3351 0.3858
Schistosoma mansoni cytochrome P450 0.0029 0.0126 0.0145
Brugia malayi hypoxia-induced factor 1 0.031 0.3078 0.3543
Loa Loa (eye worm) hypothetical protein 0.0025 0.009 0.0101
Loa Loa (eye worm) neuronal acetylcholine receptor protein 0.0084 0.0707 0.0811
Loa Loa (eye worm) hypothetical protein 0.0072 0.058 0.0666
Loa Loa (eye worm) hypothetical protein 0.0022 0.0055 0.0061
Schistosoma mansoni netrin receptor unc5 0.0032 0.0164 0.0189
Loa Loa (eye worm) acetylcholine receptor protein 0.0084 0.0707 0.0811
Loa Loa (eye worm) hypothetical protein 0.0025 0.009 0.0101
Schistosoma mansoni nAChR subunit 0.0182 0.1739 0.2007
Echinococcus multilocularis dna polymerase eta 0.0039 0.0238 0.0238
Mycobacterium ulcerans hypothetical protein 0.0074 0.0602 0.3873
Schistosoma mansoni lozenge 0.0054 0.0394 0.0455
Echinococcus multilocularis axis inhibition protein axin 0.0021 0.0041 0.0041
Brugia malayi Sodium:neurotransmitter symporter family protein 0.0088 0.0743 0.0853
Mycobacterium ulcerans cytochrome P450 123A3 Cyp123A3 0.0029 0.0126 0.0609
Brugia malayi Neurotransmitter-gated ion-channel ligand binding domain containing protein 0.0084 0.0707 0.0811
Schistosoma mansoni biogenic amine receptor 0.0022 0.0055 0.0064
Loa Loa (eye worm) acetylcholine receptor alpha subunit 0.0182 0.1739 0.2
Loa Loa (eye worm) hypothetical protein 0.0098 0.0855 0.0982
Brugia malayi orphan nuclear receptor NR2E1 0.0064 0.0499 0.0572
Echinococcus granulosus rhodopsin orphan GPCR 0.0022 0.0055 0.0055
Echinococcus granulosus glycine receptor subunit alpha 1 0.0182 0.1739 0.1739
Echinococcus granulosus expressed protein 0.0403 0.4059 0.4059
Loa Loa (eye worm) hypothetical protein 0.0033 0.0167 0.0189
Loa Loa (eye worm) gonadotropin-releasing hormone receptor 2 0.0022 0.0055 0.0061
Loa Loa (eye worm) serotonin transporter b 0.0088 0.0743 0.0853
Plasmodium vivax AP endonuclease (DNA-[apurinic or apyrimidinic site] lyase), putative 0.002 0.0037 0.0231
Echinococcus granulosus neuropeptide receptor 0.0022 0.0055 0.0055
Schistosoma mansoni growth hormone secretagogue receptor 0.0022 0.0055 0.0064
Trichomonas vaginalis DNA helicase recq, putative 0.0044 0.0285 0.0535
Loa Loa (eye worm) hypothetical protein 0.0098 0.0855 0.0982
Brugia malayi hypothetical protein 0.0084 0.0707 0.0811
Trypanosoma cruzi STE group serine/threonine-protein kinase, putative 0.0026 0.0097 0.0314
Brugia malayi Acetylcholine receptor protein, alpha-like chain 1 precursor 0.0084 0.0707 0.0811
Loa Loa (eye worm) cytochrome P450 family protein 0.0088 0.0745 0.0856
Loa Loa (eye worm) beta-LACTamase domain containing family member 0.0074 0.0602 0.069
Trypanosoma brucei DNA polymerase kappa, putative 0.0039 0.0238 0.0787
Loa Loa (eye worm) PXA domain-containing protein 0.0021 0.0041 0.0044
Echinococcus granulosus nuclear receptor 2DBD gamma 0.0136 0.1256 0.1256
Echinococcus multilocularis gamma aminobutyric acid receptor subunit 0.0084 0.0707 0.0707
Echinococcus multilocularis ecdysone induced protein 78C 0.0136 0.1256 0.1256
Echinococcus multilocularis ankyrin repeat and death domain containing protein 0.0032 0.0164 0.0164
Trichomonas vaginalis DNA polymerase IV / kappa, putative 0.0039 0.0238 0.0434
Loa Loa (eye worm) CXXC zinc finger family protein 0.0059 0.0444 0.0509
Echinococcus multilocularis carbonic anhydrase II 0.024 0.2341 0.2341
Loa Loa (eye worm) hypothetical protein 0.0021 0.0041 0.0044
Brugia malayi Blistered cuticle protein 3 0.0025 0.009 0.0101
Echinococcus granulosus RUN 0.004 0.0247 0.0247
Onchocerca volvulus 0.0084 0.0707 0.1437
Brugia malayi nuclear receptor RXR 0.0064 0.0499 0.0572
Brugia malayi beta-lactamase family protein 0.0074 0.0602 0.069
Brugia malayi Neurotransmitter-gated ion-channel ligand binding domain containing protein 0.0084 0.0707 0.0811
Echinococcus multilocularis aryl hydrocarbon receptor 0.0026 0.0097 0.0097
Loa Loa (eye worm) ACC-1 protein 0.0182 0.1739 0.2
Brugia malayi nuclear receptor NHR-88 0.0064 0.0499 0.0572
Echinococcus multilocularis ATP dependent DNA helicase Q5 0.0018 0.0014 0.0014
Onchocerca volvulus 0.004 0.0247 0.0445
Brugia malayi Nuclear hormone receptor family member nhr-19 0.0136 0.1256 0.1445
Schistosoma mansoni hypothetical protein 0.0032 0.0164 0.019
Echinococcus multilocularis beta adrenergic receptor kinase 0.0021 0.0041 0.0041
Echinococcus granulosus tm gpcr rhodopsin 0.0022 0.0055 0.0055
Mycobacterium tuberculosis Probable cytochrome P450 123 Cyp123 0.0029 0.0126 0.0256
Schistosoma mansoni neurotransmitter gated ion channel 0.0098 0.0855 0.0987
Loa Loa (eye worm) hypothetical protein 0.0098 0.0858 0.0985
Echinococcus granulosus ferritin 0.0026 0.0093 0.0093
Loa Loa (eye worm) hypothetical protein 0.0074 0.0602 0.069
Brugia malayi hypothetical protein 0.0021 0.0041 0.0044
Onchocerca volvulus 0.0025 0.009 0.0106
Brugia malayi PAS domain containing protein 0.01 0.0875 0.1005
Loa Loa (eye worm) RNA binding protein 0.0068 0.0542 0.0622
Schistosoma mansoni biogenic amine (dopamine) receptor 0.0022 0.0055 0.0064
Echinococcus granulosus Cys loop ligand gated ion channel subunit 0.0084 0.0707 0.0707
Loa Loa (eye worm) ACC-1 protein 0.0182 0.1739 0.2
Echinococcus granulosus rhodopsin orphan GPCR 0.0022 0.0055 0.0055
Brugia malayi intermediate filament protein 0.0026 0.0097 0.0109
Schistosoma mansoni polycystin 1-related 0.004 0.0247 0.0285
Echinococcus multilocularis beta LACTamase domain containing family member 0.0074 0.0602 0.0602
Echinococcus multilocularis neuropeptides capa receptor 0.0022 0.0055 0.0055
Loa Loa (eye worm) hypothetical protein 0.0064 0.0499 0.0572
Schistosoma mansoni acetylcholine receptor subunit beta 0.0084 0.0707 0.0816
Schistosoma mansoni opsin-like receptor 0.0022 0.0055 0.0064
Loa Loa (eye worm) hypothetical protein 0.0022 0.0055 0.0061
Schistosoma mansoni biogenic amine (5HT) receptor 0.0022 0.0055 0.0064
Toxoplasma gondii ATP-dependent DNA helicase, RecQ family protein 0.0029 0.0132 0.0872
Echinococcus multilocularis diuretic hormone 44 receptor GPRdih2 0.0032 0.0164 0.0164
Brugia malayi Cation transporter family protein 0.0182 0.1739 0.2
Echinococcus multilocularis regulator of G protein signaling 3 0.0021 0.0041 0.0041
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0022 0.0055 0.0064
Schistosoma mansoni hypothetical protein 0.0022 0.0055 0.0064
Brugia malayi Melatonin receptor type 1A 0.0022 0.0055 0.0061
Echinococcus multilocularis rhodopsin orphan GPCR 0.0022 0.0055 0.0055
Trichomonas vaginalis DNA helicase recq1, putative 0.0044 0.0285 0.0535
Brugia malayi hypothetical protein 0.0084 0.0707 0.0811
Loa Loa (eye worm) hypothetical protein 0.0158 0.148 0.1702
Trichomonas vaginalis D-aminoacylase, putative 0.0074 0.0602 0.1218
Brugia malayi hypothetical protein 0.0336 0.3351 0.3858
Loa Loa (eye worm) hypothetical protein 0.0032 0.0164 0.0186
Echinococcus multilocularis nuclear receptor nhr 48 0.0064 0.0499 0.0499
Loa Loa (eye worm) hypothetical protein 0.0022 0.0055 0.0061
Brugia malayi Nuclear hormone receptor family member nhr-49 0.0136 0.1256 0.1445
Loa Loa (eye worm) hypothetical protein 0.0433 0.4371 0.5033
Echinococcus granulosus Nuclear hormone receptor family member nhr 41 0.0136 0.1256 0.1256
Brugia malayi Neurotransmitter-gated ion-channel transmembrane region family protein 0.0182 0.1739 0.2
Schistosoma mansoni regulator of G protein signaling 0.0021 0.0041 0.0047
Echinococcus granulosus 7tm_1 domain containing protein 0.0022 0.0055 0.0055
Onchocerca volvulus 0.0182 0.1739 0.3664
Loa Loa (eye worm) hypothetical protein 0.0182 0.1739 0.2
Echinococcus multilocularis serotonin receptor 0.0022 0.0055 0.0055
Brugia malayi Latrophilin receptor protein 2 0.0032 0.0164 0.0186
Loa Loa (eye worm) hypothetical protein 0.0025 0.009 0.0101
Echinococcus granulosus cytochrome P450 2K1 0.0029 0.0126 0.0126
Schistosoma mansoni biogenic amine receptor 0.0022 0.0055 0.0064
Onchocerca volvulus 0.0074 0.0602 0.121
Leishmania major cytochrome p450-like protein 0.0029 0.0126 0.041
Loa Loa (eye worm) GABA receptor subunit 0.0098 0.0855 0.0982
Brugia malayi Corticotropin releasing factor receptor 2 precursor, putative 0.0103 0.0901 0.1035
Brugia malayi Neurotransmitter-gated ion-channel ligand binding domain containing protein 0.0182 0.1739 0.2
Brugia malayi hypothetical protein 0.0112 0.1 0.1149
Brugia malayi hypothetical protein 0.0021 0.0041 0.0044
Brugia malayi Calcitonin receptor-like protein seb-1 0.0103 0.0901 0.1035
Echinococcus multilocularis Cys loop ligand gated ion channel subunit 0.0182 0.1739 0.1739
Echinococcus granulosus neuronal acetylcholine receptor subunit alpha 4 0.0182 0.1739 0.1739
Brugia malayi ecdysteroid receptor 0.0136 0.1256 0.1445
Toxoplasma gondii cytochrome p450 superfamily protein 0.0029 0.0126 0.0832
Wolbachia endosymbiont of Brugia malayi bacterioferritin/cytochrome b1 0.0026 0.0093 1
Loa Loa (eye worm) hypothetical protein 0.0074 0.0602 0.069
Loa Loa (eye worm) hypothetical protein 0.0022 0.0055 0.0061
Loa Loa (eye worm) hypothetical protein 0.0084 0.0707 0.0811
Brugia malayi hypothetical protein 0.0022 0.0055 0.0061
Brugia malayi hypothetical protein 0.0072 0.058 0.0666
Echinococcus granulosus nuclear receptor nhr 48 0.0064 0.0499 0.0499
Onchocerca volvulus 0.004 0.0247 0.0445
Brugia malayi Nuclear hormone receptor family member nhr-25 0.0136 0.1256 0.1445
Echinococcus multilocularis neuropeptide FF receptor 2 0.0022 0.0055 0.0055
Brugia malayi hypothetical protein 0.0025 0.009 0.0101
Echinococcus multilocularis nuclear receptor 2DBD gamma 0.0064 0.0499 0.0499
Mycobacterium tuberculosis Conserved hypothetical protein 0.0041 0.0259 0.0535
Brugia malayi nuclear receptor subfamily 1, group D, member 1, putative 0.0064 0.0499 0.0572
Loa Loa (eye worm) nuclear hormone receptor family member nhr-40 0.0136 0.1256 0.1445
Onchocerca volvulus 0.0022 0.0055 0.0031
Brugia malayi gonadotropin-releasing hormone receptor 2 0.0022 0.0055 0.0061
Trypanosoma cruzi DNA polymerase kappa, putative 0.0039 0.0238 0.0787
Loa Loa (eye worm) nuclear hormone receptor family member nhr-14 0.0136 0.1256 0.1445
Loa Loa (eye worm) hypothetical protein 0.0022 0.0055 0.0061
Loa Loa (eye worm) cytochrome P450 family protein 0.0056 0.0408 0.0466
Loa Loa (eye worm) hypothetical protein 0.0025 0.009 0.0101
Schistosoma mansoni cpg binding protein 0.0062 0.048 0.0553
Mycobacterium ulcerans cytochrome P450 187A4 Cyp187A4 0.0029 0.0126 0.0609
Schistosoma mansoni z-protein (S1r protein) 0.0021 0.0041 0.0047
Echinococcus granulosus axis inhibition protein axin 0.0021 0.0041 0.0041
Echinococcus multilocularis neuropeptide receptor 0.0022 0.0055 0.0055
Echinococcus multilocularis COUP TF:Svp nuclear hormone receptor 0.0136 0.1256 0.1256
Schistosoma mansoni tar DNA-binding protein 0.0068 0.0542 0.0626
Loa Loa (eye worm) hypothetical protein 0.0018 0.0014 0.0013
Schistosoma mansoni axis inhibition protein axin 0.0021 0.0041 0.0047
Loa Loa (eye worm) aryl Hydrocarbon receptor Associated protein family member 0.0026 0.0097 0.0108
Schistosoma mansoni hypothetical protein 0.0528 0.5369 0.6197
Mycobacterium ulcerans cytochrome p450 150 cyp150 0.0029 0.0126 0.0609
Entamoeba histolytica hypothetical protein 0.0112 0.1 1
Loa Loa (eye worm) hypothetical protein 0.0025 0.009 0.0101
Mycobacterium tuberculosis Probable cytochrome P450 130 Cyp130 0.0029 0.0126 0.0256
Echinococcus multilocularis terminal deoxycytidyl transferase rev1 0.0039 0.0238 0.0238
Loa Loa (eye worm) hypothetical protein 0.0022 0.0055 0.0061
Schistosoma mansoni voltage-gated potassium channel 0.004 0.0247 0.0285
Mycobacterium leprae conserved hypothetical protein 0.0074 0.0602 0.3668
Echinococcus multilocularis retinoic acid receptor rxr beta a retinoic acid receptor rxr alpha a retinoic acid receptor rxr alpha 0.0259 0.2543 0.2543
Trypanosoma brucei DNA polymerase kappa, putative 0.0039 0.0238 0.0787
Loa Loa (eye worm) runx1 0.0054 0.0394 0.0451
Echinococcus multilocularis tm gpcr rhodopsin gpcr rhodopsin superfamily 0.0022 0.0055 0.0055
Echinococcus granulosus peroxidasin 0.0025 0.009 0.009
Schistosoma mansoni hypothetical protein 0.0032 0.0164 0.019
Loa Loa (eye worm) hypothetical protein 0.0022 0.0055 0.0061
Schistosoma mansoni Tr4/Tr2 (homologue) 0.0136 0.1256 0.145
Brugia malayi ecdysone receptor 0.0064 0.0499 0.0572
Schistosoma mansoni hypothetical protein 0.0022 0.0055 0.0064
Echinococcus multilocularis nuclear factor of activated T cells 5 0.0166 0.1567 0.1567
Echinococcus multilocularis rhodopsin orphan GPCR 0.0022 0.0055 0.0055
Loa Loa (eye worm) pre-SET domain-containing protein family protein 0.0406 0.4086 0.4704
Schistosoma mansoni regulator of G protein signaling 0.0021 0.0041 0.0047
Loa Loa (eye worm) hypothetical protein 0.0182 0.1739 0.2
Onchocerca volvulus 0.0022 0.0055 0.0031
Echinococcus multilocularis nuclear receptor 2DBD gamma 0.0136 0.1256 0.1256
Loa Loa (eye worm) animal heme peroxidase 0.0025 0.009 0.0101
Loa Loa (eye worm) hypothetical protein 0.0084 0.0707 0.0811
Schistosoma mansoni nAChR subunit 0.0182 0.1739 0.2007
Echinococcus granulosus beta-adrenergic receptor kinase 0.0021 0.0041 0.0041
Onchocerca volvulus 0.0074 0.0602 0.121
Schistosoma mansoni muscarinic acetylcholine (GAR) receptor 0.0022 0.0055 0.0064
Mycobacterium ulcerans endonuclease IV 0.0158 0.148 0.9897
Schistosoma mansoni regulator of G protein signaling 0.0021 0.0041 0.0047
Echinococcus multilocularis tm gpcr rhodopsin gpcr rhodopsin superfamily 0.0022 0.0055 0.0055
Echinococcus granulosus nuclear receptor subfamily 4 group A 0.0064 0.0499 0.0499
Loa Loa (eye worm) hypothetical protein 0.0022 0.0055 0.0061
Loa Loa (eye worm) hypothetical protein 0.0036 0.0203 0.0231
Echinococcus multilocularis fmrfamide receptor 0.0022 0.0055 0.0055
Leishmania major hypothetical protein, conserved 0.0074 0.0602 0.2
Schistosoma mansoni opsin-like receptor 0.0022 0.0055 0.0064
Brugia malayi Eukaryotic-type carbonic anhydrase family protein 0.024 0.2341 0.2694
Loa Loa (eye worm) eukaryotic-type carbonic anhydrase 0.0055 0.0397 0.0455
Trichomonas vaginalis voltage and ligand gated potassium channel, putative 0.0034 0.0186 0.0321
Schistosoma mansoni loxhd1 0.004 0.0247 0.0285
Brugia malayi beta-lactamase family protein 0.0074 0.0602 0.069
Loa Loa (eye worm) hypothetical protein 0.0182 0.1739 0.2
Echinococcus granulosus ATP dependent DNA helicase Q5 0.0018 0.0014 0.0014
Echinococcus multilocularis Mitotic checkpoint protein PRCC, C terminal 0.013 0.1192 0.1192
Loa Loa (eye worm) hypothetical protein 0.0084 0.0707 0.0811
Entamoeba histolytica hypothetical protein 0.0021 0.0041 0.0043
Echinococcus granulosus intermediate filament protein 0.0026 0.0097 0.0097
Echinococcus multilocularis g protein linked acetylcholine receptor gar 2a 0.0022 0.0055 0.0055
Loa Loa (eye worm) hypothetical protein 0.0084 0.0707 0.0811
Brugia malayi G-protein coupled receptor 0.0022 0.0055 0.0061
Loa Loa (eye worm) hypoxia-induced factor 1 0.031 0.3078 0.3543
Loa Loa (eye worm) hypothetical protein 0.0072 0.058 0.0666
Giardia lamblia DINP protein human, muc B family 0.0039 0.0238 1
Echinococcus granulosus Nuclear hormone receptor HR96 0.0064 0.0499 0.0499
Leishmania major mitochondrial DNA polymerase beta-PAK, putative 0.0143 0.1325 0.4417
Trypanosoma brucei Lanosterol 14-alpha demethylase 0.0029 0.0126 0.041
Schistosoma mansoni rab6-interacting 0.004 0.0247 0.0285
Trypanosoma cruzi mitochondrial DNA polymerase beta-PAK, putative 0.0143 0.1325 0.4417
Echinococcus granulosus FTZ F1 alpha 0.0136 0.1256 0.1256
Schistosoma mansoni ferritin light chain 0.0026 0.0093 0.0107
Echinococcus multilocularis nAChR subunit 0.0098 0.0855 0.0855
Schistosoma mansoni myosin xvIII 0.0022 0.0055 0.0064
Echinococcus granulosus expressed protein 0.0026 0.0093 0.0093
Echinococcus granulosus serotonin transporter 0.0088 0.0743 0.0743
Onchocerca volvulus 0.0026 0.0097 0.012
Schistosoma mansoni aldehyde dehydrogenase 0.0059 0.0447 0.0516
Loa Loa (eye worm) histone methyltransferase 0.002 0.0038 0.0041
Brugia malayi Neurotransmitter-gated ion-channel transmembrane region family protein 0.0098 0.0855 0.0982
Echinococcus granulosus glycine receptor subunit beta 0.0182 0.1739 0.1739
Echinococcus multilocularis glycine receptor subunit alpha 1 0.0182 0.1739 0.1739
Loa Loa (eye worm) RGS-3 protein 0.0021 0.0041 0.0044
Loa Loa (eye worm) hypothetical protein 0.0022 0.0055 0.0061
Schistosoma mansoni family S12 unassigned peptidase (S12 family) 0.0074 0.0602 0.0694
Loa Loa (eye worm) hypothetical protein 0.0025 0.009 0.0101
Mycobacterium tuberculosis Probable cytochrome P450 144 Cyp144 0.0029 0.0126 0.0256
Loa Loa (eye worm) hypothetical protein 0.0059 0.0446 0.0511
Schistosoma mansoni hypothetical protein 0.0022 0.0055 0.0064
Mycobacterium tuberculosis Possible penicillin-binding protein 0.0473 0.4796 1
Schistosoma mansoni serine/threonine protein kinase 0.0021 0.0041 0.0047
Loa Loa (eye worm) hypothetical protein 0.0025 0.009 0.0101
Loa Loa (eye worm) hypothetical protein 0.0041 0.0259 0.0295
Echinococcus multilocularis alpha 1A adrenergic receptor 0.0022 0.0055 0.0055
Plasmodium falciparum ADP-dependent DNA helicase RecQ 0.0039 0.0229 0.1529
Schistosoma mansoni thyroid hormone receptor 0.0267 0.2625 0.303
Brugia malayi Neurotransmitter-gated ion-channel ligand binding domain containing protein 0.0182 0.1739 0.2
Schistosoma mansoni photoreceptor-specific nuclear receptor related 0.0136 0.1256 0.145
Brugia malayi Tachykinin-like peptides receptor 99D 0.0022 0.0055 0.0061
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0022 0.0055 0.0064
Trichomonas vaginalis conserved hypothetical protein 0.0026 0.0097 0.0129
Echinococcus multilocularis Nuclear hormone receptor HR96 0.0064 0.0499 0.0499
Echinococcus granulosus carbonic anhydrase 0.0055 0.0397 0.0397
Schistosoma mansoni hypothetical protein 0.0032 0.0164 0.019
Echinococcus granulosus sex peptide receptor 0.0022 0.0055 0.0055
Echinococcus granulosus survival motor neuron protein 1 0.0237 0.2308 0.2308
Echinococcus multilocularis nicotinic acetylcholine receptor subunit alpha 8 0.0182 0.1739 0.1739
Echinococcus multilocularis carbonic anhydrase 0.0055 0.0397 0.0397
Loa Loa (eye worm) hypothetical protein 0.0021 0.0041 0.0044
Mycobacterium ulcerans cytochrome P450 51B1 Cyp51B1 0.0029 0.0126 0.0609
Echinococcus granulosus tumor protein p63 0.0365 0.3658 0.3658
Loa Loa (eye worm) hypothetical protein 0.0136 0.1256 0.1445
Echinococcus multilocularis lamin 0.0026 0.0097 0.0097
Echinococcus multilocularis microtubule associated protein 2 0.0675 0.6909 0.6909
Brugia malayi latrophilin 2 splice variant baaae 0.007 0.056 0.0642
Trypanosoma cruzi ubiquitin carboxyl-terminal hydrolase, putative 0.0036 0.0203 0.0669
Echinococcus granulosus tm gpcr rhodopsin 0.0022 0.0055 0.0055
Loa Loa (eye worm) hypothetical protein 0.0021 0.0043 0.0047
Schistosoma mansoni retinoic acid receptor RXR 0.0331 0.33 0.3808
Brugia malayi Doublecortin family protein 0.004 0.0247 0.0282
Toxoplasma gondii ATP-dependent DNA helicase, RecQ family protein 0.0018 0.0014 0.0075
Echinococcus granulosus Cys loop ligand gated ion channel subunit 0.0182 0.1739 0.1739
Mycobacterium ulcerans cytochrome P450 191A3 Cyp191A3 0.0029 0.0126 0.0609
Loa Loa (eye worm) hypothetical protein 0.0032 0.0164 0.0186
Loa Loa (eye worm) AGC/GRK/GRK protein kinase 0.0021 0.0041 0.0044
Echinococcus multilocularis Nuclear hormone receptor family member nhr 41 0.0136 0.1256 0.1256
Echinococcus granulosus nicotinic acetylcholine receptor subunit type 0.0182 0.1739 0.1739
Brugia malayi Nuclear hormone receptor family member nhr-1 0.0136 0.1256 0.1445
Schistosoma mansoni histone-lysine n-methyltransferase setb1 0.0059 0.0446 0.0515
Brugia malayi Cation transporter family protein 0.0182 0.1739 0.2
Schistosoma mansoni nAChR subunit 0.0182 0.1739 0.2007
Mycobacterium tuberculosis Probable cytochrome P450 137 Cyp137 0.0029 0.0126 0.0256
Schistosoma mansoni acetylcholine receptor-related 0.0084 0.0707 0.0816
Brugia malayi Carbonic anhydrase like protein 2 precursor 0.0055 0.0397 0.0455
Mycobacterium tuberculosis Conserved hypothetical protein 0.0039 0.0238 0.0491
Echinococcus granulosus rhodopsin orphan GPCR 0.0022 0.0055 0.0055
Brugia malayi follicle stimulating hormone receptor 0.0476 0.4821 0.5551
Schistosoma mansoni ubiquitin-specific peptidase 8 (C19 family) 0.0036 0.0203 0.0234
Onchocerca volvulus 0.0088 0.0743 0.1516
Schistosoma mansoni nAChR subunit 0.0182 0.1739 0.2007
Echinococcus multilocularis neuropeptide receptor 0.0022 0.0055 0.0055
Loa Loa (eye worm) hypothetical protein 0.0022 0.0055 0.0061
Echinococcus multilocularis nuclear receptor subfamily 4 group A 0.0064 0.0499 0.0499
Onchocerca volvulus 0.0022 0.0055 0.0031
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0022 0.0055 0.0064
Brugia malayi nuclear receptor RXR 0.0072 0.058 0.0666
Schistosoma mansoni aryl hydrocarbon receptor 0.01 0.0875 0.101
Mycobacterium tuberculosis Probable cytochrome P450 139 Cyp139 0.0029 0.0126 0.0256
Loa Loa (eye worm) receptor family ligand binding region containing protein 0.0144 0.1336 0.1537
Echinococcus granulosus nAChR subunit 0.0182 0.1739 0.1739
Trichomonas vaginalis conserved hypothetical protein 0.0021 0.0041 0.0009
Brugia malayi bZIP transcription factor family protein 0.0276 0.2723 0.3134
Trypanosoma brucei DNA polymerase kappa, putative 0.0039 0.0238 0.0787
Schistosoma mansoni norepinephrine/norepinephrine transporter 0.0088 0.0743 0.0858
Echinococcus multilocularis allatostatin A receptor 0.0022 0.0055 0.0055
Echinococcus multilocularis g protein coupled receptor 0.0022 0.0055 0.0055
Schistosoma mansoni Cys-loop ligand gated ion channel subunit 0.0098 0.0855 0.0987
Brugia malayi A-kinase anchor protein 10, precursor 0.0021 0.0041 0.0044
Brugia malayi Serotonin receptor 0.0022 0.0055 0.0061
Echinococcus granulosus nicotinic acetylcholine receptor subunit alpha 8 0.0182 0.1739 0.1739
Schistosoma mansoni tar DNA-binding protein 0.0068 0.0542 0.0626
Onchocerca volvulus 0.0022 0.0055 0.0031
Echinococcus multilocularis neuropeptide s receptor 0.0969 1 1
Trypanosoma cruzi carbonic anhydrase-like protein, putative 0.024 0.2341 0.7809
Trypanosoma brucei DNA polymerase kappa, putative 0.0027 0.0109 0.0357
Trypanosoma cruzi DNA polymerase kappa, putative 0.0039 0.0238 0.0787
Schistosoma mansoni nuclear hormone receptor 0.0064 0.0499 0.0576
Brugia malayi hypothetical protein 0.0084 0.0707 0.0811
Loa Loa (eye worm) hypothetical protein 0.0088 0.0743 0.0853
Schistosoma mansoni regulator of G protein signaling 17 19 20 (rgs17 19 20) 0.0021 0.0041 0.0047
Echinococcus granulosus growth hormone secretagogue receptor type 1 0.0022 0.0055 0.0055
Schistosoma mansoni neurotransmitter gated ion channel 0.0084 0.0707 0.0816
Schistosoma mansoni rab geranylgeranyl transferase alpha subunit 0.0039 0.0238 0.0275
Echinococcus multilocularis Basic leucine zipper (bZIP) transcription factor 0.0276 0.2723 0.2723
Schistosoma mansoni ubiquitin-specific peptidase 2 (C19 family) 0.0036 0.0203 0.0234
Trichomonas vaginalis conserved hypothetical protein 0.0021 0.0041 0.0009
Echinococcus granulosus dna polymerase kappa 0.0039 0.0238 0.0238
Trypanosoma brucei DNA polymerase IV, putative 0.0039 0.0238 0.0787
Schistosoma mansoni carbonic anhydrase 0.0055 0.0397 0.0459
Brugia malayi Bloom's syndrome protein homolog 0.0044 0.0285 0.0325
Loa Loa (eye worm) hypothetical protein 0.0064 0.0499 0.0572
Schistosoma mansoni biogenic amine (5HT) receptor 0.0022 0.0055 0.0064
Echinococcus multilocularis orexin receptor type 2 0.0022 0.0055 0.0055
Schistosoma mansoni lipoxygenase 0.0113 0.101 0.1166
Loa Loa (eye worm) carbonic anhydrase 3 0.024 0.2341 0.2694
Brugia malayi Nuclear hormone receptor-like 1 0.0072 0.058 0.0666
Treponema pallidum bacterioferrin (TpF1) 0.0026 0.0093 0.079
Echinococcus granulosus Aryl hydrocarbon receptor nuclear 0.0026 0.0097 0.0097
Schistosoma mansoni intermediate filament proteins 0.0026 0.0097 0.0112
Brugia malayi conserved hypotetical protein 0.0064 0.0499 0.0572
Echinococcus multilocularis fatty acid amide hydrolase 1 0.0098 0.0858 0.0858
Echinococcus granulosus serotonin receptor 0.0022 0.0055 0.0055
Trypanosoma cruzi mitochondrial DNA polymerase beta, putative 0.0302 0.2997 1
Echinococcus granulosus aryl hydrocarbon receptor 0.0026 0.0097 0.0097
Loa Loa (eye worm) hypothetical protein 0.004 0.0247 0.0282
Loa Loa (eye worm) ligand-Gated ion Channel family member 0.0182 0.1739 0.2
Mycobacterium ulcerans cytochrome P450 143A3 Cyp143A3 0.0029 0.0126 0.0609
Echinococcus granulosus pyroglutamylated rfamide peptide receptor 0.0022 0.0055 0.0055
Loa Loa (eye worm) hypothetical protein 0.0022 0.0055 0.0061
Loa Loa (eye worm) hypothetical protein 0.0182 0.1739 0.2
Echinococcus multilocularis nuclear receptor 2DBD gamma 0.0136 0.1256 0.1256
Brugia malayi G-protein-linked acetylcholine receptor protein 2, putative 0.0022 0.0055 0.0061
Mycobacterium tuberculosis Possible cytochrome P450 135A1 Cyp135A1 0.0029 0.0126 0.0256
Schistosoma mansoni ap endonuclease 0.002 0.0037 0.0042
Echinococcus multilocularis thyrotropin releasing hormone receptor 0.0022 0.0055 0.0055
Trichomonas vaginalis conserved hypothetical protein 0.0021 0.0041 0.0009
Echinococcus granulosus biogenic amine 5HT receptor 0.0022 0.0055 0.0055
Loa Loa (eye worm) hypothetical protein 0.0025 0.009 0.0101
Schistosoma mansoni apoferritin-2 0.0026 0.0093 0.0107
Toxoplasma gondii exonuclease III APE 0.002 0.0037 0.0231
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0022 0.0055 0.0064
Brugia malayi hypothetical protein 0.0022 0.0055 0.0061
Loa Loa (eye worm) hypothetical protein 0.0074 0.0602 0.069
Loa Loa (eye worm) immunoglobulin I-set domain-containing protein 0.0032 0.0164 0.0186
Echinococcus granulosus rhodopsin orphan GPCR 0.0022 0.0055 0.0055
Loa Loa (eye worm) latrophilin receptor protein 2 0.0032 0.0164 0.0186
Loa Loa (eye worm) hypothetical protein 0.0022 0.0055 0.0061
Echinococcus multilocularis glycine receptor subunit alpha 1 0.0182 0.1739 0.1739
Loa Loa (eye worm) nuclear hormone receptor family member nhr-31 0.0136 0.1256 0.1445
Onchocerca volvulus Netrin receptor homolog 0.0032 0.0164 0.0265
Echinococcus multilocularis musashi 0.0026 0.0097 0.0097
Loa Loa (eye worm) hypothetical protein 0.0182 0.1739 0.2
Loa Loa (eye worm) unidentified vitellogenin-linked transcript protein 6 0.0022 0.0055 0.0061
Loa Loa (eye worm) hypothetical protein 0.0098 0.0855 0.0982
Trypanosoma brucei DNA polymerase IV, putative 0.0039 0.0238 0.0787
Loa Loa (eye worm) hypothetical protein 0.0064 0.0499 0.0572
Schistosoma mansoni ferritin 0.0026 0.0093 0.0107
Echinococcus granulosus g protein coupled receptor 0.0022 0.0055 0.0055
Loa Loa (eye worm) 5-hydroxytryptamine 2C receptor 0.0022 0.0055 0.0061
Loa Loa (eye worm) hypothetical protein 0.0182 0.1739 0.2
Entamoeba histolytica recQ family helicase, putative 0.0023 0.007 0.0342
Brugia malayi CXXC zinc finger family protein 0.0059 0.0444 0.0509
Echinococcus granulosus dnaJ subfamily B 0.0842 0.8665 0.8665
Schistosoma mansoni carbonic anhydrase-related 0.0055 0.0397 0.0459
Trichomonas vaginalis adenylate cyclase, type VII, putative 0.0026 0.0097 0.0129
Brugia malayi hypothetical protein 0.0237 0.2308 0.2657
Trichomonas vaginalis Clan CA, family C19, ubiquitin hydrolase-like cysteine peptidase 0.0036 0.0203 0.0359
Mycobacterium ulcerans esterase/lipase LipP 0.0074 0.0602 0.3873
Echinococcus multilocularis ATP dependent DNA helicase Q1 0.0018 0.0014 0.0014
Loa Loa (eye worm) hypothetical protein 0.0084 0.0707 0.0811
Schistosoma mansoni thyrotropin-releasing hormone receptor 0.0022 0.0055 0.0064
Echinococcus multilocularis Aryl hydrocarbon receptor nuclear 0.0026 0.0097 0.0097
Echinococcus granulosus carbonic anhydrase 0.0055 0.0397 0.0397
Loa Loa (eye worm) hypothetical protein 0.0022 0.0055 0.0061
Brugia malayi acetylcholine receptor protein, alpha-like chain, putative 0.0182 0.1739 0.2
Entamoeba histolytica hypothetical protein 0.0112 0.1 1
Echinococcus multilocularis ubiquitin specific protease 41 0.0036 0.0203 0.0203
Mycobacterium ulcerans cytochrome P450 189A7 Cyp189A7 0.0029 0.0126 0.0609
Echinococcus multilocularis isocitrate dehydrogenase 2 (NADP+) 0.0017 0.0003 0.0003
Loa Loa (eye worm) hypothetical protein 0.0027 0.0105 0.0118
Loa Loa (eye worm) pigment dispersing factor receptor c 0.0103 0.0901 0.1035
Loa Loa (eye worm) hypothetical protein 0.0022 0.0055 0.0061
Schistosoma mansoni nuclear receptor 2DBD-gamma 0.0136 0.1256 0.145
Onchocerca volvulus 0.0053 0.0385 0.0742
Loa Loa (eye worm) hypothetical protein 0.031 0.3081 0.3546
Echinococcus granulosus regulator of G protein signaling 7 0.0021 0.0041 0.0041
Loa Loa (eye worm) hypothetical protein 0.0182 0.1739 0.2
Brugia malayi Animal haem peroxidase family protein 0.0025 0.009 0.0101
Entamoeba histolytica hypothetical protein 0.0021 0.0041 0.0043
Mycobacterium tuberculosis Probable cytochrome P450 monooxygenase 142 Cyp142 0.0029 0.0126 0.0256
Trypanosoma brucei ubiquitin carboxyl-terminal hydrolase, putative 0.0036 0.0203 0.0669
Schistosoma mansoni nAChR subunit 0.0182 0.1739 0.2007
Schistosoma mansoni DNA helicase recq1 0.0018 0.0014 0.0016
Loa Loa (eye worm) hypothetical protein 0.0064 0.0499 0.0572
Mycobacterium ulcerans bacterioferritin BfrB 0.0026 0.0093 0.0383
Trypanosoma cruzi STE group serine/threonine-protein kinase, putative 0.0026 0.0097 0.0314
Schistosoma mansoni nuclear hormone receptor superfamily protein-related 0.0064 0.0499 0.0576
Loa Loa (eye worm) hypothetical protein 0.0098 0.0855 0.0982
Loa Loa (eye worm) glutamate receptor 0.0033 0.0167 0.0189
Mycobacterium tuberculosis Conserved protein 0.0074 0.0602 0.125
Brugia malayi TAR-binding protein 0.0068 0.0542 0.0622
Brugia malayi RNA recognition motif domain containing protein 0.0068 0.0542 0.0622
Trypanosoma brucei DNA polymerase kappa, putative 0.0039 0.0238 0.0787
Brugia malayi Probable G protein-coupled receptor kinase F19C6.1, putative 0.0021 0.0041 0.0044
Loa Loa (eye worm) hypothetical protein 0.0022 0.0055 0.0061
Loa Loa (eye worm) hypothetical protein 0.0136 0.1256 0.1445
Echinococcus granulosus thyrotropin releasing hormone receptor 0.0022 0.0055 0.0055
Schistosoma mansoni regulator of G protein signaling 0.0021 0.0041 0.0047
Echinococcus multilocularis histone lysine N methyltransferase SETMAR 0.0059 0.0446 0.0446
Brugia malayi sulfakinin receptor protein 0.0022 0.0055 0.0061
Echinococcus granulosus regulator of G protein signaling 3 0.0021 0.0041 0.0041
Brugia malayi Nuclear hormone receptor family member nhr-14 0.0136 0.1256 0.1445
Echinococcus granulosus axis inhibition protein axin 0.0021 0.0041 0.0041
Brugia malayi glutamate-gated chloride channel alpha3A subunit, putative 0.0084 0.0707 0.0811
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0022 0.0055 0.0064
Echinococcus granulosus allatostatin A receptor 0.0022 0.0055 0.0055
Brugia malayi Neurotransmitter-gated ion-channel ligand binding domain containing protein 0.0182 0.1739 0.2
Toxoplasma gondii endonuclease IV APN 0.0158 0.148 1
Loa Loa (eye worm) hypothetical protein 0.0022 0.0055 0.0061
Brugia malayi ORL1-like opioid receptor 0.0022 0.0055 0.0061
Trypanosoma cruzi PAS-domain containing phosphoglycerate kinase, putative 0.0026 0.0097 0.0314
Onchocerca volvulus 0.0136 0.1256 0.2623
Echinococcus multilocularis nicotinic acetylcholine receptor subunit type 0.0084 0.0707 0.0707
Loa Loa (eye worm) nuclear hormone receptor family member nhr-49 0.0136 0.1256 0.1445
Echinococcus multilocularis neuropeptide Y receptor 0.0022 0.0055 0.0055
Mycobacterium tuberculosis Probable cytochrome P450 128 Cyp128 0.0029 0.0126 0.0256
Onchocerca volvulus 0.0026 0.0097 0.0121
Loa Loa (eye worm) hypothetical protein 0.0182 0.1739 0.2
Schistosoma mansoni ankyrin 23/unc44 0.0032 0.0164 0.0189
Loa Loa (eye worm) hypothetical protein 0.0136 0.1256 0.1445
Loa Loa (eye worm) hypothetical protein 0.0268 0.2643 0.3042
Echinococcus multilocularis regulator of G protein signaling 7 0.0021 0.0041 0.0041
Schistosoma mansoni nuclear hormone receptor 0.0064 0.0499 0.0576
Echinococcus multilocularis ferritin 0.0026 0.0093 0.0093
Brugia malayi Pre-SET motif family protein 0.0406 0.4086 0.4704
Plasmodium vivax SET domain protein, putative 0.0059 0.0446 0.3003
Brugia malayi Eukaryotic-type carbonic anhydrase family protein 0.0055 0.0397 0.0455
Brugia malayi nuclear hormone receptor 0.0136 0.1256 0.1445
Schistosoma mansoni carbonic anhydrase II (carbonate dehydratase II) 0.024 0.2341 0.2702
Loa Loa (eye worm) hypothetical protein 0.0022 0.0055 0.0061
Loa Loa (eye worm) hypothetical protein 0.0035 0.0191 0.0217
Mycobacterium leprae putative cytochrome p450 0.0029 0.0126 0.0237
Echinococcus granulosus GPCR family 2 0.0032 0.0164 0.0164
Echinococcus granulosus nAChR subunit 0.0098 0.0855 0.0855
Brugia malayi nuclear hormone receptor family member odr-7 0.0064 0.0499 0.0572
Loa Loa (eye worm) hypothetical protein 0.0026 0.0097 0.0108
Trypanosoma cruzi apurinic/apyrimidinic endonuclease 0.002 0.0037 0.0114
Echinococcus granulosus g protein coupled receptor 0.0022 0.0055 0.0055
Mycobacterium tuberculosis Probable cytochrome P450 124 Cyp124 0.0029 0.0126 0.0256
Mycobacterium ulcerans epimerase 0.0041 0.0259 0.1524
Leishmania major DNA polymerase eta, putative 0.0039 0.0238 0.0787
Entamoeba histolytica ubiquitin carboxyl-terminal hydrolase domain containing protein 0.0036 0.0203 0.1726
Loa Loa (eye worm) hypothetical protein 0.0074 0.0602 0.069
Schistosoma mansoni peptide (FMRFamide/somatostatin)-like receptor 0.0022 0.0055 0.0064
Echinococcus granulosus neuropeptide FF receptor 2 0.0022 0.0055 0.0055
Schistosoma mansoni sodium/chloride dependent transporter 0.0088 0.0743 0.0858
Echinococcus granulosus single minded 2 0.0077 0.0637 0.0637
Loa Loa (eye worm) nuclear hormone receptor 0.0064 0.0499 0.0572
Echinococcus granulosus jun protein 0.0276 0.2723 0.2723
Loa Loa (eye worm) hypothetical protein 0.0064 0.0499 0.0572
Brugia malayi Immunoglobulin I-set domain containing protein 0.0032 0.0164 0.0186
Brugia malayi Neurotransmitter-gated ion-channel ligand binding domain containing protein 0.0182 0.1739 0.2
Onchocerca volvulus 0.0026 0.0097 0.0121
Loa Loa (eye worm) hypothetical protein 0.0064 0.0499 0.0572
Plasmodium falciparum apurinic/apyrimidinic endonuclease Apn1, putative 0.0158 0.148 1
Echinococcus granulosus neuropeptide Y receptor 0.0022 0.0055 0.0055
Loa Loa (eye worm) hypothetical protein 0.0074 0.0602 0.069
Echinococcus granulosus G protein coupled 5 hydroxytryptamine receptor 0.0022 0.0055 0.0055
Loa Loa (eye worm) hypothetical protein 0.0022 0.0055 0.0061
Mycobacterium ulcerans aldehyde dehydrogenase 0.0059 0.0447 0.2811
Toxoplasma gondii hypothetical protein 0.0055 0.0397 0.2671
Schistosoma mansoni nAChR subunit (ShAR1-beta-like) 0.0182 0.1739 0.2007
Schistosoma mansoni histone-lysine n-methyltransferase suv9 0.0059 0.0446 0.0515
Echinococcus multilocularis peroxidasin 0.0025 0.009 0.009
Trichomonas vaginalis conserved hypothetical protein 0.0021 0.0041 0.0009
Schistosoma mansoni lamin 0.0026 0.0097 0.0112
Brugia malayi hypothetical protein 0.0072 0.058 0.0666
Echinococcus granulosus fmrfamide receptor 0.0022 0.0055 0.0055
Loa Loa (eye worm) hypothetical protein 0.0182 0.1739 0.2
Onchocerca volvulus 0.0022 0.0055 0.0031
Schistosoma mansoni ap endonuclease 0.002 0.0037 0.0042
Schistosoma mansoni ferritin light chain 0.0026 0.0093 0.0107
Trichomonas vaginalis DNA polymerase eta, putative 0.0039 0.0238 0.0434
Schistosoma mansoni hypothetical protein 0.013 0.1192 0.1376
Trypanosoma cruzi cytochrome p450-like protein, putative 0.0029 0.0126 0.041
Echinococcus multilocularis g protein coupled receptor 0.0022 0.0055 0.0055
Brugia malayi calcium-independent alpha-latrotoxin receptor 2, putative 0.0032 0.0164 0.0186
Echinococcus multilocularis cpg binding protein 0.0062 0.048 0.048
Loa Loa (eye worm) hypothetical protein 0.0022 0.0055 0.0061
Mycobacterium tuberculosis Probable cytochrome P450 143 Cyp143 0.0029 0.0126 0.0256
Schistosoma mansoni terminal deoxycytidyl transferase 0.0039 0.0238 0.0275
Brugia malayi Neurotransmitter-gated ion-channel ligand binding domain containing protein 0.0182 0.1739 0.2
Echinococcus granulosus nuclear receptor subfamily 1 group D 0.0072 0.058 0.058
Echinococcus multilocularis dro:myosuppressin receptor 0.0022 0.0055 0.0055
Loa Loa (eye worm) neuropeptide F receptor 0.0022 0.0055 0.0061
Schistosoma mansoni peroxidasin 0.0025 0.009 0.0104
Onchocerca volvulus 0.0182 0.1739 0.3664
Onchocerca volvulus 0.0182 0.1739 0.3664
Loa Loa (eye worm) TAR-binding protein 0.0068 0.0542 0.0622
Trypanosoma cruzi mitochondrial DNA polymerase beta-PAK, putative 0.0052 0.0367 0.1218
Mycobacterium ulcerans cytochrome P450 125A7 Cyp125A7 0.0029 0.0126 0.0609
Schistosoma mansoni carbonic anhydrase-related 0.0055 0.0397 0.0459
Brugia malayi ATP-dependent DNA helicase, RecQ family protein 0.0018 0.0014 0.0013
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0022 0.0055 0.0064
Brugia malayi Ubiquitin carboxyl-terminal hydrolase family protein 0.0036 0.0203 0.0231
Echinococcus multilocularis dnaJ subfamily B 0.0842 0.8665 0.8665
Trichomonas vaginalis adenylate cyclase, putative 0.0026 0.0097 0.0129
Loa Loa (eye worm) hypothetical protein 0.0025 0.009 0.0101
Loa Loa (eye worm) hypothetical protein 0.0084 0.0707 0.0811
Brugia malayi Regulator of G protein signaling domain containing protein 0.0021 0.0041 0.0044
Trypanosoma brucei DNA polymerase kappa, putative 0.0039 0.0238 0.0787
Onchocerca volvulus 0.0022 0.0055 0.0031
Loa Loa (eye worm) RecQ helicase 0.0044 0.0285 0.0325
Mycobacterium tuberculosis Probable conserved lipoprotein 0.0074 0.0602 0.125
Echinococcus multilocularis tm gpcr rhodopsin gpcr rhodopsin superfamily 0.0022 0.0055 0.0055
Schistosoma mansoni nicotinic acetylcholine receptor alpha 0.0098 0.0855 0.0987
Brugia malayi RE15519p 0.0022 0.0055 0.0061
Loa Loa (eye worm) hypothetical protein 0.0064 0.0499 0.0572
Schistosoma mansoni tar DNA-binding protein 0.0068 0.0542 0.0626
Trypanosoma brucei DNA polymerase eta, putative 0.0039 0.0238 0.0787
Brugia malayi hypothetical protein 0.0022 0.0055 0.0061
Loa Loa (eye worm) CYP4Cod1 0.0056 0.0408 0.0466
Loa Loa (eye worm) hypothetical protein 0.0022 0.0055 0.0061
Brugia malayi Ligand-binding domain of nuclear hormone receptor family protein 0.0136 0.1256 0.1445
Brugia malayi Dopamine receptor protein 1 0.0022 0.0055 0.0061
Schistosoma mansoni cellular tumor antigen P53 0.0053 0.0385 0.0444
Echinococcus multilocularis nicotinic acetylcholine receptor a11 subunit 0.0182 0.1739 0.1739
Schistosoma mansoni hypothetical protein 0.007 0.056 0.0646
Loa Loa (eye worm) hypothetical protein 0.0025 0.009 0.0101
Loa Loa (eye worm) hypothetical protein 0.0022 0.0055 0.0061
Echinococcus granulosus 7TM GPCR rhodopsin 0.0022 0.0055 0.0055
Schistosoma mansoni neuropeptide receptor 0.0022 0.0055 0.0064
Brugia malayi neuropeptide F receptor 0.0022 0.0055 0.0061
Schistosoma mansoni amidase 0.0098 0.0858 0.099
Brugia malayi photoreceptor-specific nuclear receptor 0.0136 0.1256 0.1445
Leishmania major lanosterol 14-alpha-demethylase, putative 0.0029 0.0126 0.041
Brugia malayi Nuclear hormone receptor family member nhr-3 0.0136 0.1256 0.1445
Echinococcus multilocularis dna polymerase kappa 0.0039 0.0238 0.0238
Schistosoma mansoni ferritin 0.0026 0.0093 0.0107
Mycobacterium tuberculosis Probable endonuclease IV End (endodeoxyribonuclease IV) (apurinase) 0.0158 0.148 0.3083
Schistosoma mansoni Cys-loop ligand gated ion channel subunit 0.0182 0.1739 0.2007
Loa Loa (eye worm) solute carrier family 6 member 4 0.0088 0.0743 0.0853
Onchocerca volvulus Dopamine\/Ecdysteroid receptor homolog 0.0022 0.0055 0.0031
Echinococcus granulosus dna polymerase eta 0.0039 0.0238 0.0238
Loa Loa (eye worm) cytochrome P450 0.0029 0.0126 0.0142
Echinococcus granulosus metabotropic glutamate receptor 5 0.0033 0.0167 0.0167
Brugia malayi Nuclear hormone receptor family member nhr-19 0.0136 0.1256 0.1445
Trichomonas vaginalis penicillin-binding protein, putative 0.0074 0.0602 0.1218
Echinococcus granulosus beta LACTamase domain containing family member 0.0074 0.0602 0.0602
Loa Loa (eye worm) norepinephrine transporter 0.0088 0.0743 0.0853
Loa Loa (eye worm) hypothetical protein 0.0025 0.009 0.0101
Schistosoma mansoni hypothetical protein 0.0048 0.033 0.0381
Brugia malayi Eukaryotic-type carbonic anhydrase family protein 0.0055 0.0397 0.0455
Brugia malayi nuclear hormone receptor 0.0064 0.0499 0.0572
Loa Loa (eye worm) hypothetical protein 0.0072 0.058 0.0666
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0022 0.0055 0.0064
Schistosoma mansoni hypothetical protein 0.0055 0.0397 0.0459
Schistosoma mansoni peptide (FMRFamide/somatostatin)-like receptor 0.0022 0.0055 0.0064
Loa Loa (eye worm) hypothetical protein 0.0022 0.0055 0.0061
Echinococcus granulosus neuropeptides capa receptor 0.0022 0.0055 0.0055
Echinococcus multilocularis histone lysine methyltransferase setb histone lysine methyltransferase eggless 0.0059 0.0446 0.0446
Echinococcus granulosus tm gpcr rhodopsin 0.0022 0.0055 0.0055
Trichomonas vaginalis conserved hypothetical protein 0.0026 0.0097 0.0129
Schistosoma mansoni hypothetical protein 0.0224 0.218 0.2516
Echinococcus granulosus tachykinin peptides receptor 99D 0.0022 0.0055 0.0055
Loa Loa (eye worm) nicotinic acetylcholine receptor alpha subunit 0.0182 0.1739 0.2
Mycobacterium ulcerans bacterioferritin BfrA 0.0026 0.0093 0.0383
Onchocerca volvulus Protein ultraspiracle homolog 0.0136 0.1256 0.2623
Schistosoma mansoni peroxidasin 0.0025 0.009 0.0104
Echinococcus multilocularis glycine receptor subunit beta 0.0182 0.1739 0.1739
Loa Loa (eye worm) hypothetical protein 0.0136 0.1256 0.1445
Echinococcus multilocularis aldehyde dehydrogenase, mitochondrial 0.0059 0.0447 0.0447
Loa Loa (eye worm) hypothetical protein 0.0039 0.0238 0.0271
Echinococcus multilocularis metabotropic glutamate receptor 5 0.0033 0.0167 0.0167
Brugia malayi hypothetical protein 0.0217 0.21 0.2417
Loa Loa (eye worm) hypothetical protein 0.0022 0.0055 0.0061
Echinococcus granulosus g-protein coupled receptor 0.0022 0.0055 0.0055
Trypanosoma cruzi DNA polymerase beta thumb, putative 0.0042 0.027 0.0892
Schistosoma mansoni hypothetical protein 0.0032 0.0164 0.019
Echinococcus granulosus g protein linked acetylcholine receptor gar 2a 0.0022 0.0055 0.0055
Trichomonas vaginalis regulator of G protein signaling 5, rgs5, putative 0.0021 0.0041 0.0009
Brugia malayi hypothetical protein 0.0022 0.0055 0.0061
Echinococcus granulosus Basic leucine zipper bZIP transcription 0.0112 0.1 0.1
Entamoeba histolytica deoxycytidyl transferase, putative 0.0039 0.0238 0.2091
Loa Loa (eye worm) hypothetical protein 0.004 0.0247 0.0282
Brugia malayi hypothetical protein 0.0022 0.0055 0.0061
Echinococcus granulosus peptide allatostatin:somatostatin 0.0022 0.0055 0.0055
Entamoeba histolytica hypothetical protein 0.0112 0.1 1
Loa Loa (eye worm) hypothetical protein 0.0025 0.009 0.0101
Echinococcus granulosus ankyrin repeat and death domain containing protein 0.0032 0.0164 0.0164
Brugia malayi hypothetical protein 0.0119 0.1073 0.1233
Echinococcus multilocularis lamin dm0 0.0026 0.0097 0.0097
Entamoeba histolytica hypothetical protein 0.0112 0.1 1
Loa Loa (eye worm) animal heme peroxidase 0.0025 0.009 0.0101
Schistosoma mansoni alpha-1 adrenergic receptor 0.0022 0.0055 0.0064
Schistosoma mansoni FTZ-F1 nuclear receptor-like protein 0.0136 0.1256 0.145
Plasmodium falciparum ATP-dependent DNA helicase Q1 0.0018 0.0014 0.0075
Loa Loa (eye worm) hypothetical protein 0.0021 0.0041 0.0044
Leishmania major protein kinase, putative 0.0026 0.0097 0.0314
Echinococcus granulosus nuclear receptor 2DBD gamma 0.0064 0.0499 0.0499
Onchocerca volvulus 0.0098 0.0855 0.1757
Loa Loa (eye worm) hypothetical protein 0.0022 0.0055 0.0061
Trichomonas vaginalis conserved hypothetical protein 0.0021 0.0041 0.0009
Echinococcus granulosus G protein coupled receptor 139 0.0022 0.0055 0.0055
Trypanosoma cruzi Lanosterol 14-alpha demethylase 0.0029 0.0126 0.041
Loa Loa (eye worm) hypothetical protein 0.0084 0.0707 0.0811
Trypanosoma brucei unspecified product 0.0039 0.0238 0.0787
Loa Loa (eye worm) intermediate filament tail domain-containing protein 0.0026 0.0097 0.0109
Loa Loa (eye worm) hypothetical protein 0.0433 0.4371 0.5033
Schistosoma mansoni peptide (allatostatin)-like receptor 0.0022 0.0055 0.0064
Brugia malayi hypothetical protein 0.0064 0.0499 0.0572
Trichomonas vaginalis conserved hypothetical protein 0.0026 0.0097 0.0129
Loa Loa (eye worm) hypothetical protein 0.0064 0.0499 0.0572
Brugia malayi Putative carbonic anhydrase 5 precursor 0.024 0.2341 0.2694
Mycobacterium ulcerans cytochrome P450 124A1, Cyp124A1 0.0029 0.0126 0.0609
Echinococcus granulosus lipoxygenase domain containing protein 0.004 0.0247 0.0247
Leishmania major DNA polymerase kappa, putative 0.0039 0.0238 0.0787
Mycobacterium ulcerans cytochrome P450 188A3 Cyp188A3 0.0029 0.0126 0.0609
Schistosoma mansoni DNA polymerase eta 0.0039 0.0238 0.0275
Onchocerca volvulus Bile acid receptor homolog 0.0136 0.1256 0.2623
Brugia malayi hypothetical protein 0.0022 0.0055 0.0061
Echinococcus granulosus Polycystic kidney disease protein 0.004 0.0247 0.0247
Brugia malayi hypothetical protein 0.0022 0.0055 0.0061
Schistosoma mansoni histone-lysine n-methyltransferase setb1 0.0059 0.0446 0.0515
Trypanosoma brucei cytochrome P450, putative 0.0056 0.0408 0.1352
Brugia malayi acetylcholine receptor, alpha-type subunit unc-38 precursor 0.0182 0.1739 0.2
Onchocerca volvulus 0.0182 0.1739 0.3664
Echinococcus granulosus regulator of G protein signaling 7 0.0021 0.0041 0.0041
Onchocerca volvulus 0.0182 0.1739 0.3664
Onchocerca volvulus 0.0074 0.0602 0.121

Activities

Activity type Activity value Assay description Source Reference
IC50 (binding) = 150 uM Inhibitory concentration against Hepatitis C virus serine protease ChEMBL. 15239657

Phenotypes

Whole-cell/tissue/organism interactions

We have no records of whole-cell/tissue assays done with this compound What does this mean?

Many chemical entities in TDR Targets come from high-throughput screenings with whole cells or tissue samples, and not all assayed compounds have been tested against a single a single target protein, probably because they get ruled out during screening process. Even if these compounds may have not been of interest in the original screening, they may come as interesting leads for other screening assays. Furthermore, we may be able to propose drug-target associations using chemical similarities and network patterns.

Annotated phenotypes:

We have no manually annotated phenotypes for this drug. What does this mean? / Care to help?
In TDR Targets, information about phenotypes that are caused by drugs, or by genetic manipulation of cells (e.g. gene knockouts or knockdowns) is manually curated from the literature. These descriptions help to describe the potential of the target for drug development. If no information is available for this gene or if the information is incomplete, this may mean that i) the papers containing this information either appeared after the curation effort for this organism was carried out or they were inadvertently missed by curators; or that ii) the curation effort for this organism has not yet started.
 
In any case, if you have information about papers containing relevant validation data for this target, please log in using your TDR Targets username and password and send them to us using the corresponding form in this page (only visible to registered users) or contact us.

External resources for this compound

Bibliographic References

1 literature reference was collected for this gene.

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