Detailed information for compound 255662

Basic information

Technical information
  • Name: Unnamed compound
  • MW: 383.916 | Formula: C16H18ClN3O2S2
  • H donors: 1 H acceptors: 2 LogP: 3.3 Rotable bonds: 6
    Rule of 5 violations (Lipinski): 1
  • SMILES: N=C(N(c1cccc(c1)[S+](C)[O-])C)Nc1cc(ccc1Cl)[S+](C)[O-]
  • InChi: 1S/C16H18ClN3O2S2/c1-20(11-5-4-6-12(9-11)23(2)21)16(18)19-15-10-13(24(3)22)7-8-14(15)17/h4-10H,1-3H3,(H2,18,19)
  • InChiKey: AKPIPDYJVYYOIY-UHFFFAOYSA-N  


Substructure search Similarity search

Network

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Synonyms

No synonyms found for this compound

Targets

Known targets for this compound

Species Target name Source Bibliographic reference
Homo sapiens glutamate receptor, ionotropic, N-methyl-D-aspartate 3A Starlite/ChEMBL References

Predicted pathogen targets for this compound

By orthology
No druggable targets predicted by orthology data
By sequence similarity to non orthologous known druggable targets
No druggable targets predicted by sequence similarity
Obtained from network model

Ranking Plot

Putative Targets List

Species Potential target Raw Global Species
Leishmania major DNA polymerase kappa, putative,DNA polymerase IV, putative 0.0043 0.0121 0.0595
Brugia malayi MH2 domain containing protein 0.0026 0.0028 0.0065
Trichomonas vaginalis DNA polymerase IV / kappa, putative 0.0065 0.0236 0.0466
Trypanosoma brucei GTP-binding nuclear protein rtb2, putative 0.0065 0.0235 0.1498
Brugia malayi DOMON domain containing protein 0.0095 0.0391 0.089
Trypanosoma cruzi Present in the outer mitochondrial membrane proteome 4 0.0034 0.0072 0.0335
Trypanosoma brucei DNA polymerase IV, putative 0.0065 0.0236 0.1503
Schistosoma mansoni glutamate receptor AMPA 0.004 0.0104 0.0136
Echinococcus granulosus geminin 0.1091 0.5613 0.5612
Trypanosoma cruzi mitochondrial DNA polymerase beta-PAK, putative 0.0045 0.0129 0.0699
Trypanosoma cruzi ISWI complex protein 0.0032 0.0061 0.0262
Echinococcus multilocularis GPCR, family 2 0.0152 0.0689 0.0687
Wolbachia endosymbiont of Brugia malayi exonuclease III 0.0039 0.0096 0.0717
Brugia malayi Smad1 0.0026 0.0028 0.0065
Echinococcus granulosus poly (ADP ribose) polymerase 0.0044 0.0123 0.012
Echinococcus granulosus TGF beta signal transducer SmadC 0.0026 0.0028 0.0026
Loa Loa (eye worm) hypothetical protein 0.0051 0.0162 0.0328
Brugia malayi Latrophilin receptor protein 2 0.0152 0.0689 0.1567
Toxoplasma gondii Erv1 / Alr family protein 0.0034 0.0072 0.0182
Echinococcus multilocularis lysine specific demethylase 6a 0.0044 0.0121 0.0118
Onchocerca volvulus 0.0049 0.0148 0.0291
Trypanosoma brucei unspecified product 0.0025 0.0024 0.015
Giardia lamblia Endonuclease/Exonuclease/phosphatase 0.0039 0.0096 0.0193
Plasmodium falciparum GTP-binding nuclear protein RAN/TC4 0.0065 0.0235 0.2733
Brugia malayi Inositol-1 0.0039 0.0098 0.0224
Brugia malayi PHD-finger family protein 0.0063 0.0221 0.0503
Schistosoma mansoni SmCB2 peptidase (C01 family) 0.0141 0.0632 0.0823
Leishmania major mitochondrial DNA polymerase beta-PAK, putative 0.0151 0.0687 0.4268
Leishmania major DNA repair protein, putative 0.0037 0.0086 0.0372
Loa Loa (eye worm) hypothetical protein 0.0036 0.0084 0.0166
Schistosoma mansoni acetyl-CoA C-acetyltransferase 0.0049 0.0149 0.0194
Trypanosoma cruzi mitochondrial DNA polymerase beta-PAK, putative 0.0151 0.0687 0.4299
Echinococcus granulosus bloom syndrome protein 0.0086 0.0342 0.034
Loa Loa (eye worm) nuclear hormone receptor family member nhr-14 0.0022 0.0008 0.0011
Brugia malayi MH1 domain containing protein 0.0026 0.0028 0.0065
Mycobacterium tuberculosis Probable esterase LipL 0.0039 0.0098 0.0486
Echinococcus granulosus histone acetyltransferase KAT2B 0.0154 0.0701 0.0698
Schistosoma mansoni SET domain protein 0.0021 0.0005 0.0006
Loa Loa (eye worm) jmjC domain-containing protein 0.0044 0.0121 0.0243
Echinococcus granulosus peroxidasin 0.0051 0.0162 0.016
Echinococcus multilocularis Transcription factor, JmjC domain containing protein 0.0293 0.1427 0.1425
Loa Loa (eye worm) hypothetical protein 0.0051 0.0162 0.0328
Schistosoma mansoni caspase-3 (C14 family) 0.0028 0.004 0.0052
Trichomonas vaginalis fructose-bisphosphate aldolase, putative 0.0611 0.3094 0.6164
Echinococcus granulosus terminal deoxycytidyl transferase rev1 0.0036 0.0082 0.008
Onchocerca volvulus 0.0039 0.0098 0.0191
Trypanosoma brucei heat shock protein, putative 0.0034 0.0073 0.0466
Echinococcus multilocularis importin subunit beta 1 0.0089 0.0358 0.0356
Loa Loa (eye worm) hypothetical protein 0.0051 0.0162 0.0328
Schistosoma mansoni SET domain protein 0.0039 0.0098 0.0128
Echinococcus granulosus mothers against decapentaplegic 5 0.0026 0.0028 0.0026
Loa Loa (eye worm) hypothetical protein 0.0062 0.022 0.0445
Plasmodium vivax apurinic/apyrimidinic endonuclease Apn1, putative 0.0076 0.0294 0.3411
Brugia malayi Cytochrome P450 family protein 0.0035 0.0076 0.0172
Trypanosoma cruzi mitochondrial DNA polymerase beta, putative 0.032 0.1571 1
Schistosoma mansoni tar DNA-binding protein 0.0067 0.0246 0.032
Schistosoma mansoni hypothetical protein 0.0152 0.0689 0.0897
Echinococcus multilocularis ATP dependent DNA helicase Q5 0.0048 0.0143 0.014
Echinococcus multilocularis caspase 2 0.0028 0.004 0.0038
Toxoplasma gondii heat shock protein HSP90 0.0034 0.0073 0.0185
Schistosoma mansoni peroxidasin 0.0051 0.0162 0.0211
Echinococcus granulosus diuretic hormone 44 receptor GPRdih2 0.0152 0.0689 0.0687
Echinococcus multilocularis citrate lyase subunit beta protein 0.0026 0.0029 0.0026
Trypanosoma cruzi DNA polymerase kappa, putative 0.0065 0.0236 0.1392
Schistosoma mansoni poly [ADP-ribose] polymerase 0.0283 0.1374 0.1788
Trichomonas vaginalis Clan CD, family C14, metacaspase-like cysteine peptidase 0.0028 0.004 0.0075
Trypanosoma cruzi myo-inositol-1(or 4)-monophosphatase 1, putative 0.0039 0.0098 0.0505
Trichomonas vaginalis Clan CD, family C14, metacaspase-like cysteine peptidase 0.0028 0.004 0.0075
Brugia malayi Glycosyl hydrolases family 31 protein 0.0173 0.0798 0.1814
Plasmodium falciparum histone acetyltransferase GCN5 0.0043 0.0117 0.1357
Brugia malayi DOMON domain containing protein 0.0095 0.0391 0.089
Brugia malayi nuclear hormone receptor 0.0022 0.0008 0.0019
Mycobacterium ulcerans hypothetical protein 0.0169 0.0777 0.5236
Plasmodium falciparum heat shock protein 90 0.0034 0.0073 0.0851
Brugia malayi Nuclear hormone receptor family member nhr-3 0.0022 0.0008 0.0019
Onchocerca volvulus Peroxidasin homolog 0.0051 0.0162 0.0318
Echinococcus granulosus methyl CpG binding domain protein 2 0.0036 0.008 0.0078
Schistosoma mansoni histone-lysine n-methyltransferase setb1 0.016 0.0731 0.0952
Brugia malayi Copper type II ascorbate-dependent monooxygenase, C-terminal domain containing protein 0.0497 0.2498 0.568
Mycobacterium tuberculosis Possible penicillin-binding protein 0.025 0.1206 0.8242
Loa Loa (eye worm) TAR-binding protein 0.0067 0.0246 0.0499
Loa Loa (eye worm) hypothetical protein 0.0051 0.0162 0.0328
Echinococcus granulosus poly (ADP ribose) polymerase 0.0088 0.0353 0.035
Loa Loa (eye worm) Smad1 0.0026 0.0028 0.0052
Trypanosoma cruzi hypothetical protein, conserved 0.0225 0.1075 0.6801
Toxoplasma gondii histone lysine demethylase JMJC1/KDM5D/JARID1D 0.0069 0.0254 0.0639
Schistosoma mansoni bromodomain-containing nuclear protein 1 brd1 0.0063 0.0221 0.0288
Trichomonas vaginalis heat shock protein, putative 0.0027 0.0036 0.0068
Trichomonas vaginalis heat shock protein, putative 0.0027 0.0036 0.0068
Plasmodium vivax GTP-binding nuclear protein RAN/TC4, putative 0.0065 0.0235 0.2733
Loa Loa (eye worm) hypothetical protein 0.0039 0.0098 0.0196
Schistosoma mansoni smad1 5 8 and 0.0026 0.0028 0.0037
Trypanosoma brucei heat shock protein, putative 0.0034 0.0073 0.0466
Toxoplasma gondii Erv1 / Alr family protein 0.0034 0.0072 0.0182
Giardia lamblia Heat shock protein HSP 90-alpha 0.0034 0.0073 0.012
Brugia malayi Animal haem peroxidase family protein 0.0051 0.0162 0.0369
Brugia malayi Glutamate receptor 1 precursor 0.004 0.0104 0.0237
Onchocerca volvulus Peroxidase homolog 0.0051 0.0162 0.0318
Loa Loa (eye worm) hypothetical protein 0.0089 0.0361 0.0736
Brugia malayi Blistered cuticle protein 3 0.0051 0.0162 0.0369
Schistosoma mansoni methyl-cpg binding protein mbd 0.0036 0.008 0.0104
Echinococcus multilocularis NADP dependent isocitrate dehydrogenase 0.0067 0.0242 0.024
Loa Loa (eye worm) hypothetical protein 0.0131 0.0578 0.1183
Plasmodium falciparum ADP-dependent DNA helicase RecQ 0.0078 0.0301 0.3498
Echinococcus granulosus hepatocyte nuclear factor 4 alpha 0.0022 0.0008 0.0006
Loa Loa (eye worm) hypothetical protein 0.0044 0.0121 0.0243
Brugia malayi cathepsin B-like cysteine proteinase 0.0141 0.0632 0.1438
Echinococcus granulosus aldehyde dehydrogenase mitochondrial 0.0066 0.0239 0.0237
Mycobacterium leprae PROBABLE ENDONUCLEASE IV END (ENDODEOXYRIBONUCLEASE IV) (APURINASE) 0.0076 0.0294 0.181
Echinococcus multilocularis beta LACTamase domain containing family member 0.0039 0.0098 0.0096
Plasmodium vivax histone acetyltransferase GCN5, putative 0.0052 0.0163 0.1896
Brugia malayi beta-lactamase family protein 0.0039 0.0098 0.0223
Brugia malayi polk-prov protein 0.0041 0.0105 0.0239
Brugia malayi RNA binding protein 0.0067 0.0246 0.0558
Echinococcus multilocularis tar DNA binding protein 0.0067 0.0246 0.0243
Toxoplasma gondii hypothetical protein 0.0052 0.0163 0.0411
Trypanosoma brucei Metacaspase-4 0.0028 0.004 0.0255
Leishmania major hypothetical protein, conserved 0.0039 0.0098 0.045
Schistosoma mansoni hypothetical protein 0.0052 0.0163 0.0212
Schistosoma mansoni tar DNA-binding protein 0.0067 0.0246 0.032
Trichomonas vaginalis neutral alpha-glucosidase ab precursor, putative 0.0038 0.0094 0.0181
Wolbachia endosymbiont of Brugia malayi fructose-1,6-bisphosphatase 0.0039 0.0098 0.0752
Trichomonas vaginalis inositol monophosphatase, putative 0.0039 0.0098 0.0191
Trypanosoma cruzi heat shock protein 85, putative 0.0034 0.0073 0.0342
Loa Loa (eye worm) cytochrome P450 family protein 0.0035 0.0076 0.0149
Leishmania major heat shock protein 83-1 0.0034 0.0073 0.0288
Trichomonas vaginalis fructose-bisphosphate aldolase, putative 0.0611 0.3094 0.6164
Schistosoma mansoni RAR-like nuclear receptor 0.0022 0.0008 0.0011
Schistosoma mansoni ATP-binding cassette transporter 0.004 0.0104 0.0136
Echinococcus granulosus intermediate filament protein 0.0142 0.0635 0.0633
Schistosoma mansoni ubiquitously transcribed sex (X/Y) chromosome tetratricopeptide repeat protein-related 0.0044 0.0121 0.0157
Schistosoma mansoni tyrosyl-DNA phosphodiesterase 0.007 0.0259 0.0338
Trypanosoma brucei ATP-dependent DEAD/H DNA helicase recQ, putative 0.0056 0.0184 0.1172
Brugia malayi nuclear receptor NHR-88 0.0022 0.0008 0.0019
Schistosoma mansoni ap endonuclease 0.0039 0.0096 0.0124
Leishmania major heat shock protein 83-1 0.0034 0.0073 0.0288
Loa Loa (eye worm) beta-LACTamase domain containing family member 0.0039 0.0098 0.0196
Trichomonas vaginalis bromodomain-containing protein, putative 0.0052 0.0163 0.032
Onchocerca volvulus Huntingtin homolog 0.0132 0.0585 0.1161
Plasmodium vivax enoyl-acyl carrier protein reductase 0.0185 0.0861 1
Trichomonas vaginalis alpha-glucosidase, putative 0.0038 0.0094 0.0181
Echinococcus granulosus suppression of tumorigenicity 18 protein 0.0058 0.0194 0.0192
Schistosoma mansoni histone-lysine n-methyltransferase setb1 0.016 0.0731 0.0952
Trypanosoma cruzi metacaspase, putative 0.0028 0.004 0.0128
Loa Loa (eye worm) transcription factor SMAD2 0.038 0.1886 0.3876
Loa Loa (eye worm) hypothetical protein 0.0041 0.0105 0.021
Schistosoma mansoni Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) 0.0098 0.0406 0.0528
Loa Loa (eye worm) hypothetical protein 0.0148 0.067 0.1372
Plasmodium vivax importin-beta 2, putative 0.0089 0.0358 0.4161
Loa Loa (eye worm) RecQ helicase 0.0086 0.0342 0.0698
Loa Loa (eye worm) hypothetical protein 0.0155 0.0706 0.1448
Brugia malayi AMP-binding enzyme family protein 0.0049 0.0148 0.0337
Loa Loa (eye worm) hypothetical protein 0.008 0.0314 0.064
Trypanosoma cruzi poly(ADP-ribose) polymerase, putative 0.0155 0.0706 0.4426
Schistosoma mansoni terminal deoxycytidyl transferase 0.0036 0.0082 0.0107
Schistosoma mansoni alkaline phosphatase 0.0172 0.0796 0.1036
Onchocerca volvulus 0.0022 0.0008 0.0012
Schistosoma mansoni NADP-specific isocitrate dehydrogenase 0.0067 0.0242 0.0315
Trypanosoma cruzi apurinic/apyrimidinic endonuclease, putative 0.0039 0.0096 0.0486
Trypanosoma brucei cysteine peptidase C (CPC) 0.0049 0.0151 0.0963
Giardia lamblia Cathepsin B precursor 0.0049 0.0151 0.0375
Brugia malayi Nuclear hormone receptor family member nhr-31 0.0022 0.0008 0.0019
Echinococcus granulosus poly adp ribose polymerase 2 0.0155 0.0706 0.0704
Trichomonas vaginalis Clan CD, family C14, metacaspase-like cysteine peptidase 0.0028 0.004 0.0075
Loa Loa (eye worm) hypothetical protein 0.0051 0.0162 0.0328
Trypanosoma brucei heat shock protein 90, putative 0.0034 0.0073 0.0466
Entamoeba histolytica exodeoxyribonuclease III, putative 0.0039 0.0096 0.0301
Trichomonas vaginalis sucrase-isomaltase, putative 0.0038 0.0094 0.0181
Brugia malayi Corticotropin releasing factor receptor 2 precursor, putative 0.048 0.241 0.5481
Echinococcus granulosus lysine specific demethylase 5A 0.022 0.1049 0.1046
Plasmodium vivax JmjC domain containing protein 0.0066 0.0237 0.275
Schistosoma mansoni glutamate receptor kainate 0.004 0.0104 0.0136
Trypanosoma brucei DNA polymerase eta, putative 0.0036 0.0082 0.0525
Echinococcus multilocularis polycomb protein SCMH1 0.0051 0.0158 0.0155
Brugia malayi mucosa associated lymphoid tissue lymphoma translocation protein 1 0.0028 0.004 0.0091
Plasmodium falciparum importin beta, putative 0.0089 0.0358 0.4161
Trichomonas vaginalis endoplasmin, putative 0.0021 0.0003 0.0002
Onchocerca volvulus 0.0142 0.0635 0.126
Trypanosoma cruzi metacaspase, putative 0.0028 0.004 0.0128
Plasmodium falciparum ATP-dependent DNA helicase Q1 0.0048 0.0143 0.1661
Brugia malayi Endoplasmin precursor 0.0034 0.0073 0.0167
Trypanosoma cruzi GTP-binding nuclear protein rtb2, putative 0.0065 0.0235 0.1387
Loa Loa (eye worm) hypothetical protein 0.0022 0.0008 0.0011
Onchocerca volvulus Chorion peroxidase homolog 0.0051 0.0162 0.0318
Echinococcus multilocularis lamin dm0 0.0142 0.0635 0.0633
Loa Loa (eye worm) nuclear Hormone Receptor family member 0.0022 0.0008 0.0011
Leishmania major aldehyde dehydrogenase, mitochondrial precursor 0.0066 0.0239 0.1366
Echinococcus granulosus WGR domain containing protein 0.0088 0.0353 0.035
Toxoplasma gondii HEAT repeat-containing protein 0.0089 0.0358 0.0902
Echinococcus granulosus 5'partial|histone lysine N methyltransferase SETDB2 0.0119 0.0514 0.0512
Leishmania major hypothetical protein, conserved 0.0037 0.0086 0.0372
Wolbachia endosymbiont of Brugia malayi enoyl-ACP reductase 0.0185 0.0861 1
Schistosoma mansoni hypothetical protein 0.0152 0.0689 0.0897
Echinococcus multilocularis peroxidasin 0.0051 0.0162 0.016
Echinococcus granulosus poly ADP ribose polymerase 1 0.0283 0.1374 0.1372
Loa Loa (eye worm) PHD-finger family protein 0.0063 0.0221 0.0449
Loa Loa (eye worm) hypothetical protein 0.0022 0.0008 0.0011
Loa Loa (eye worm) MH1 domain-containing protein 0.0026 0.0028 0.0052
Loa Loa (eye worm) CYP4Cod1 0.0035 0.0076 0.0149
Trypanosoma cruzi cysteine peptidase C (CPC), putative 0.0141 0.0632 0.3949
Trichomonas vaginalis hypothetical protein 0.0185 0.0861 0.171
Echinococcus multilocularis bromodomain adjacent to zinc finger domain 0.0131 0.0578 0.0575
Echinococcus granulosus SAM and MBT domain containing protein 0.0051 0.0158 0.0155
Entamoeba histolytica acyl-CoA synthetase, putative 0.0049 0.0148 0.0472
Leishmania major hypothetical protein, conserved 0.0044 0.0121 0.0598
Plasmodium vivax endoplasmin, putative 0.0034 0.0073 0.0851
Loa Loa (eye worm) animal heme peroxidase 0.0051 0.0162 0.0328
Trichomonas vaginalis Clan CA, family C1, cathepsin B-like cysteine peptidase 0.0049 0.0151 0.0296
Giardia lamblia GTP-binding nuclear protein RAN/TC4 0.0065 0.0235 0.065
Echinococcus multilocularis Smad4 0.0026 0.0028 0.0026
Loa Loa (eye worm) isocitrate dehydrogenase 0.0067 0.0242 0.0492
Treponema pallidum exodeoxyribonuclease (exoA) 0.0039 0.0096 0.0245
Echinococcus multilocularis glutamate receptor 2 0.0025 0.0026 0.0024
Echinococcus granulosus smad 0.0026 0.0028 0.0026
Trypanosoma cruzi ERV/ALR sulfhydryl oxidase domain-containing protein 0.0034 0.0072 0.0335
Echinococcus granulosus tyrosyl DNA phosphodiesterase 1 0.007 0.0259 0.0257
Entamoeba histolytica acyl-coA synthetase, putative 0.0049 0.0148 0.0472
Schistosoma mansoni thyroid hormone receptor 0.0022 0.0008 0.0011
Echinococcus multilocularis glutamate receptor, ionotrophic, AMPA 3 0.004 0.0104 0.0102
Echinococcus multilocularis DNA (apurinic or apyrimidinic site) lyase 0.0039 0.0096 0.0093
Entamoeba histolytica recQ family helicase, putative 0.0023 0.0015 0.0042
Echinococcus multilocularis microtubule associated protein 2 0.1486 0.7684 0.7684
Loa Loa (eye worm) RNA binding protein 0.0067 0.0246 0.0499
Brugia malayi jmjC domain containing protein 0.0044 0.0121 0.0275
Loa Loa (eye worm) DOMON domain-containing protein 0.0095 0.0391 0.0799
Brugia malayi jmjC domain containing protein 0.0044 0.0121 0.0275
Trypanosoma cruzi DNA polymerase beta thumb, putative 0.0045 0.0129 0.0699
Mycobacterium tuberculosis Probable fatty-acid-CoA ligase FadD3 (fatty-acid-CoA synthetase) (fatty-acid-CoA synthase) 0.0034 0.0073 0.0312
Loa Loa (eye worm) hypothetical protein 0.0036 0.0084 0.0166
Leishmania major heat shock protein 83-1 0.0034 0.0073 0.0288
Brugia malayi Isocitrate dehydrogenase 0.0067 0.0242 0.0551
Brugia malayi AMP-binding enzyme family protein 0.0049 0.0148 0.0337
Echinococcus granulosus lysosomal alpha glucosidase 0.0173 0.0798 0.0796
Mycobacterium tuberculosis Probable lipase LipD 0.0039 0.0098 0.0486
Echinococcus multilocularis Glutamate receptor, ionotropic kainate 2 0.004 0.0104 0.0102
Trichomonas vaginalis conserved hypothetical protein 0.0028 0.004 0.0075
Loa Loa (eye worm) hypothetical protein 0.0036 0.0084 0.0166
Schistosoma mansoni ran 0.0065 0.0235 0.0306
Trypanosoma cruzi mitochondrial DNA polymerase beta, putative 0.032 0.1571 1
Schistosoma mansoni bromodomain containing protein 0.0138 0.0617 0.0803
Onchocerca volvulus 0.0039 0.0098 0.0191
Schistosoma mansoni lamin 0.0142 0.0635 0.0826
Mycobacterium leprae Probable fructose bisphosphate aldolase Fba 0.0298 0.1457 1
Plasmodium vivax FAD-linked sulfhydryl oxidase ERV1, putative 0.0034 0.0072 0.0838
Brugia malayi AMP-binding enzyme family protein 0.0049 0.0148 0.0337
Mycobacterium tuberculosis Possible DNA-damage-inducible protein P DinP (DNA polymerase V) (pol IV 2) (DNA nucleotidyltransferase (DNA-directed)) 0.0043 0.0121 0.0643
Brugia malayi Nuclear hormone receptor-like 1 0.0022 0.0008 0.0019
Echinococcus granulosus guanine nucleotide binding protein Gs subunit 0.0098 0.0406 0.0404
Trypanosoma brucei DNA polymerase kappa, putative 0.0065 0.0236 0.1503
Mycobacterium tuberculosis Conserved hypothetical protein 0.0036 0.0082 0.0376
Schistosoma mansoni tar DNA-binding protein 0.0067 0.0246 0.032
Loa Loa (eye worm) glutamate receptor 1 0.004 0.0104 0.0209
Trypanosoma brucei unspecified product 0.0058 0.0198 0.126
Brugia malayi hypothetical protein 0.0051 0.0162 0.0369
Schistosoma mansoni smad1 5 8 and 0.0026 0.0028 0.0037
Echinococcus granulosus zinc finger protein 0.0047 0.0137 0.0134
Leishmania major heat shock protein 83-1 0.0034 0.0073 0.0288
Loa Loa (eye worm) hypothetical protein 0.0051 0.0162 0.0328
Echinococcus multilocularis neuropeptide receptor A26 0.1928 1 1
Schistosoma mansoni histone-lysine n-methyltransferase suv9 0.0124 0.0544 0.0708
Trichomonas vaginalis fructose-bisphosphate aldolase, putative 0.0611 0.3094 0.6164
Mycobacterium tuberculosis Probable fructose-bisphosphate aldolase Fba 0.0298 0.1457 1
Schistosoma mansoni nuclear hormone receptor 0.0022 0.0008 0.0011
Schistosoma mansoni heat shock protein 0.0034 0.0073 0.0095
Trichomonas vaginalis Importin beta-1 subunit, putative 0.0072 0.027 0.0533
Brugia malayi latrophilin 2 splice variant baaae 0.0328 0.1614 0.3669
Loa Loa (eye worm) hypothetical protein 0.0095 0.039 0.0797
Loa Loa (eye worm) nuclear hormone receptor family member nhr-41 0.0022 0.0008 0.0011
Trypanosoma cruzi isocitrate dehydrogenase [NADP], mitochondrial precursor, putative 0.0067 0.0242 0.1432
Echinococcus granulosus Transcription factor JmjC domain containing protein 0.0293 0.1427 0.1425
Echinococcus multilocularis geminin 0.1091 0.5613 0.5612
Echinococcus granulosus histone acetyltransferase KAT2B 0.0052 0.0163 0.0161
Loa Loa (eye worm) glycosyl hydrolase family 31 protein 0.0038 0.0094 0.0186
Echinococcus granulosus Glutamate receptor ionotropic kainate 2 0.004 0.0104 0.0102
Echinococcus granulosus COUP TF:Svp nuclear hormone receptor 0.0022 0.0008 0.0006
Loa Loa (eye worm) mbt repeat family protein 0.0051 0.0158 0.0318
Brugia malayi Cytochrome P450 family protein 0.0035 0.0076 0.0172
Loa Loa (eye worm) hypothetical protein 0.0051 0.0162 0.0328
Loa Loa (eye worm) hypothetical protein 0.0058 0.0194 0.0394
Echinococcus multilocularis SAM and MBT domain containing protein 0.0051 0.0158 0.0155
Echinococcus multilocularis poly (ADP ribose) polymerase 0.0065 0.0233 0.023
Loa Loa (eye worm) animal heme peroxidase 0.0051 0.0162 0.0328
Echinococcus multilocularis atpase aaa+ type core atpase aaa type core 0.1631 0.8444 0.8444
Echinococcus multilocularis Nuclear hormone receptor family member nhr 41 0.0022 0.0008 0.0006
Toxoplasma gondii heat shock protein 90, putative 0.0034 0.0073 0.0185
Echinococcus multilocularis phd:f box containing protein 0.0044 0.0121 0.0118
Echinococcus granulosus microtubule associated protein 2 0.1486 0.7684 0.7684
Leishmania major alpha glucosidase II subunit, putative 0.0038 0.0094 0.042
Trypanosoma brucei apurinic/apyrimidinic endonuclease, putative 0.0039 0.0096 0.0608
Echinococcus granulosus X box binding protein 1 0.0315 0.1545 0.1543
Leishmania major GTP-binding protein, putative 0.0065 0.0235 0.1339
Mycobacterium tuberculosis Conserved hypothetical protein 0.0169 0.0777 0.5236
Trichomonas vaginalis heat shock protein, putative 0.0034 0.0073 0.0141
Trypanosoma cruzi mitochondrial DNA polymerase beta-PAK, putative 0.0055 0.018 0.1032
Entamoeba histolytica myo-inositol monophosphatase, putative 0.0039 0.0098 0.031
Brugia malayi Copper type II ascorbate-dependent monooxygenase, C-terminal domain containing protein 0.0497 0.2498 0.568
Schistosoma mansoni cathepsin B-like peptidase (C01 family) 0.0049 0.0151 0.0197
Entamoeba histolytica hypothetical protein 0.0038 0.0093 0.0293
Giardia lamblia Histone acetyltransferase GCN5 0.0043 0.0117 0.0263
Trichomonas vaginalis D-aminoacylase, putative 0.0039 0.0098 0.0191
Brugia malayi WGR domain containing protein 0.0283 0.1374 0.3124
Schistosoma mansoni mixed-lineage leukemia protein mll 0.0026 0.003 0.0039
Brugia malayi Bromodomain containing protein 0.0071 0.0267 0.0608
Treponema pallidum fructose-bisphosphate aldolase 0.0611 0.3094 1
Mycobacterium ulcerans enoyl-(acyl carrier protein) reductase 0.0185 0.0861 0.5825
Echinococcus multilocularis X box binding protein 1 0.0315 0.1545 0.1543
Treponema pallidum heat shock protein 90 0.0027 0.0036 0.0053
Brugia malayi mbt repeat family protein 0.0051 0.0158 0.0359
Toxoplasma gondii ATP-dependent DNA helicase, RecQ family protein 0.0048 0.0143 0.036
Mycobacterium ulcerans aldehyde dehydrogenase 0.0066 0.0239 0.1475
Trypanosoma brucei DNA polymerase kappa, putative 0.0065 0.0236 0.1503
Loa Loa (eye worm) nucleolar RNA-associated protein alpha 0.0948 0.4861 1
Schistosoma mansoni lipoxygenase 0.0122 0.0533 0.0694
Entamoeba histolytica deoxycytidyl transferase, putative 0.0036 0.0082 0.0259
Echinococcus granulosus caspase 3 apoptosis cysteine peptidase 0.0028 0.004 0.0038
Schistosoma mansoni family S12 unassigned peptidase (S12 family) 0.0039 0.0098 0.0128
Schistosoma mansoni myelin transcription factor 1 myt1 0.0058 0.0194 0.0253
Echinococcus granulosus heat shock protein 0.0034 0.0073 0.0071
Echinococcus multilocularis heat shock protein 0.0034 0.0073 0.0071
Trypanosoma cruzi hypothetical protein, conserved 0.0038 0.0094 0.0473
Echinococcus multilocularis poly (ADP ribose) polymerase 1 0.0283 0.1374 0.1372
Schistosoma mansoni endoplasmin 0.0034 0.0073 0.0095
Trichomonas vaginalis fructose-bisphosphate aldolase, putative 0.0611 0.3094 0.6164
Onchocerca volvulus Dual oxidase homolog 0.0051 0.0162 0.0318
Loa Loa (eye worm) jmjC domain-containing protein 0.0044 0.0121 0.0243
Trypanosoma cruzi myo-inositol-1(or 4)-monophosphatase 1, putative 0.0039 0.0098 0.0505
Loa Loa (eye worm) ImpB/MucB/SamB family protein 0.0036 0.0082 0.0163
Loa Loa (eye worm) hypothetical protein 0.0328 0.1614 0.3315
Echinococcus multilocularis jumonji domain containing 1A 0.0044 0.0121 0.0118
Echinococcus multilocularis endoplasmin 0.0027 0.0036 0.0034
Echinococcus granulosus retinoic acid receptor rxr beta a 0.0022 0.0008 0.0006
Echinococcus multilocularis smad 0.0026 0.0028 0.0026
Trichomonas vaginalis DNA helicase recq, putative 0.0056 0.0184 0.0362
Loa Loa (eye worm) hypothetical protein 0.0215 0.102 0.2094
Schistosoma mansoni hypothetical protein 0.0152 0.0689 0.0897
Brugia malayi hypothetical protein 0.0038 0.0093 0.0212
Echinococcus granulosus bromodomain adjacent to zinc finger domain 0.0131 0.0578 0.0575
Trypanosoma cruzi isocitrate dehydrogenase, putative 0.0067 0.0242 0.1432
Leishmania major hypothetical protein, conserved 0.0225 0.1075 0.6783
Trichomonas vaginalis set domain proteins, putative 0.0978 0.5019 1
Trypanosoma brucei heat shock protein, putative 0.0034 0.0073 0.0466
Echinococcus multilocularis methyl CpG binding domain protein 2 0.0036 0.008 0.0078
Schistosoma mansoni jumonji/arid domain-containing protein 0.022 0.1049 0.1365
Echinococcus granulosus GPCR family 2 0.0152 0.0689 0.0687
Onchocerca volvulus 0.0142 0.0635 0.126
Trypanosoma cruzi hypothetical protein, conserved 0.0225 0.1075 0.6801
Brugia malayi Calcitonin receptor-like protein seb-1 0.048 0.241 0.5481
Echinococcus multilocularis Basic leucine zipper (bZIP) transcription 0.0038 0.0093 0.0091
Loa Loa (eye worm) acetyltransferase 0.0164 0.075 0.1537
Echinococcus granulosus NADP dependent isocitrate dehydrogenase 0.0067 0.0242 0.024
Brugia malayi steroid hormone receptor 0.0022 0.0008 0.0019
Brugia malayi exodeoxyribonuclease III family protein 0.0039 0.0096 0.0217
Schistosoma mansoni hypothetical protein 0.009 0.0362 0.0471
Trypanosoma cruzi heat shock protein 90, putative 0.0027 0.0036 0.0105
Schistosoma mansoni alpha-glucosidase 0.0149 0.0672 0.0874
Schistosoma mansoni jumonji domain containing protein 0.0044 0.0121 0.0157
Echinococcus granulosus cathepsin b 0.0141 0.0632 0.063
Loa Loa (eye worm) hypothetical protein 0.0022 0.0008 0.0011
Mycobacterium tuberculosis Probable isocitrate dehydrogenase [NADP] Icd1 (oxalosuccinate decarboxylase) (IDH) (NADP+-specific ICDH) (IDP) 0.0067 0.0242 0.1495
Echinococcus multilocularis caspase 8 0.0028 0.004 0.0038
Onchocerca volvulus DNA ligase 3 homolog 0.0037 0.0086 0.0167
Trypanosoma brucei DNA polymerase kappa, putative 0.0041 0.0105 0.067
Echinococcus multilocularis alkaline phosphatase, intestinal, gene 2 0.0172 0.0796 0.0794
Echinococcus granulosus tar DNA binding protein 0.0067 0.0246 0.0243
Mycobacterium tuberculosis Conserved protein 0.0039 0.0098 0.0486
Brugia malayi ImpB/MucB/SamB family protein 0.0036 0.0082 0.0187
Trypanosoma brucei ERV/ALR sulfhydryl oxidase domain-containing protein 0.0034 0.0072 0.0459
Loa Loa (eye worm) follicle stimulating hormone receptor 0.0238 0.1143 0.2346
Brugia malayi Peroxidasin 0.0051 0.0162 0.0369
Mycobacterium ulcerans beta-lactamase 0.0039 0.0098 0.0486
Toxoplasma gondii ATP-dependent DNA helicase, RecQ family protein 0.0024 0.002 0.0051
Schistosoma mansoni ap endonuclease 0.0039 0.0096 0.0124
Trypanosoma brucei DNA repair protein, putative 0.0037 0.0086 0.0548
Onchocerca volvulus 0.0095 0.0391 0.0775
Schistosoma mansoni blooms syndrome DNA helicase 0.0061 0.0215 0.0279
Trypanosoma brucei heat shock protein, putative 0.0034 0.0073 0.0466
Loa Loa (eye worm) bromodomain containing protein 0.0041 0.0107 0.0214
Schistosoma mansoni Tr4/Tr2 (homologue) 0.0022 0.0008 0.0011
Leishmania major heat shock protein 83-1 0.0034 0.0073 0.0288
Mycobacterium leprae Probable lipase LipE 0.0039 0.0098 0.0435
Plasmodium vivax hypothetical protein, conserved 0.0028 0.004 0.0466
Onchocerca volvulus 0.0978 0.502 1
Brugia malayi Nuclear hormone receptor family member nhr-19 0.0022 0.0008 0.0019
Brugia malayi jmjC domain containing protein 0.0044 0.0121 0.0275
Mycobacterium ulcerans fructose-bisphosphate aldolase 0.0298 0.1457 1
Echinococcus granulosus FAD linked sulfhydryl oxidase ALR 0.0034 0.0072 0.007
Schistosoma mansoni hypothetical protein 0.0152 0.0689 0.0897
Schistosoma mansoni hypothetical protein 0.0315 0.1545 0.2011
Echinococcus multilocularis COUP TF:Svp nuclear hormone receptor 0.0022 0.0008 0.0006
Schistosoma mansoni caspase-7 (C14 family) 0.0028 0.004 0.0052
Echinococcus granulosus lamin dm0 0.0142 0.0635 0.0633
Echinococcus multilocularis ATP dependent DNA helicase Q1 0.0048 0.0143 0.014
Brugia malayi Augmenter of liver regeneration 0.0034 0.0072 0.0164
Echinococcus multilocularis suppression of tumorigenicity 18 protein 0.0058 0.0194 0.0192
Echinococcus multilocularis caspase 0.0028 0.004 0.0038
Echinococcus multilocularis GTP binding nuclear protein Ran 0.0065 0.0235 0.0233
Trypanosoma brucei heat shock protein, putative 0.0034 0.0073 0.0466
Schistosoma mansoni tar DNA-binding protein 0.0067 0.0246 0.032
Mycobacterium tuberculosis Probable lipase LipE 0.0039 0.0098 0.0486
Trypanosoma cruzi GTP-binding nuclear protein rtb2, putative 0.0065 0.0235 0.1387
Onchocerca volvulus Peroxidase homolog 0.0051 0.0162 0.0318
Leishmania major cytochrome p450-like protein 0.0035 0.0076 0.0303
Echinococcus multilocularis histone acetyltransferase MYST2 0.0058 0.0194 0.0192
Echinococcus granulosus DNA apurinic or apyrimidinic site lyase 0.0039 0.0096 0.0093
Loa Loa (eye worm) hypothetical protein 0.0063 0.0221 0.0449
Plasmodium falciparum acyl-CoA synthetase 0.0036 0.0084 0.0973
Echinococcus granulosus neuropeptide receptor A26 0.1928 1 1
Loa Loa (eye worm) steroid hormone receptor 0.0022 0.0008 0.0011
Echinococcus granulosus endoplasmin 0.0027 0.0036 0.0034
Plasmodium vivax isocitrate dehydrogenase [NADP], mitochondrial, putative 0.0067 0.0242 0.2815
Loa Loa (eye worm) DOMON domain-containing protein 0.0095 0.0391 0.0799
Echinococcus multilocularis hepatocyte nuclear factor 4 alpha 0.0022 0.0008 0.0006
Brugia malayi Nuclear hormone receptor family member nhr-19 0.0022 0.0008 0.0019
Trypanosoma brucei DNA polymerase kappa, putative 0.0041 0.0105 0.067
Loa Loa (eye worm) nuclear hormone receptor family member nhr-31 0.0022 0.0008 0.0011
Leishmania major 4-coumarate:coa ligase-like protein 0.0049 0.0148 0.0776
Echinococcus multilocularis alkaline phosphatase 0.0172 0.0796 0.0794
Mycobacterium leprae PROBABLE FATTY-ACID-CoA LIGASE FADD2 (FATTY-ACID-CoA SYNTHETASE) (FATTY-ACID-CoA SYNTHASE) 0.0049 0.0148 0.0788
Loa Loa (eye worm) hypothetical protein 0.0132 0.0585 0.1198
Echinococcus multilocularis bromodomain adjacent to zinc finger domain 0.0075 0.0287 0.0285
Schistosoma mansoni importin beta-1 0.0089 0.0358 0.0466
Loa Loa (eye worm) hypothetical protein 0.0044 0.0121 0.0243
Schistosoma mansoni thyroid hormone receptor 0.0022 0.0008 0.0011
Loa Loa (eye worm) hypothetical protein 0.0051 0.0162 0.0328
Onchocerca volvulus 0.0157 0.0714 0.1417
Trichomonas vaginalis ap endonuclease, putative 0.0039 0.0096 0.0185
Loa Loa (eye worm) hypothetical protein 0.0049 0.0148 0.0299
Trypanosoma cruzi hypothetical protein, conserved 0.0039 0.0098 0.0503
Trichomonas vaginalis fructose-bisphosphate aldolase, putative 0.0611 0.3094 0.6164
Trypanosoma brucei Heat shock protein 83, putative 0.0034 0.0073 0.0466
Toxoplasma gondii endonuclease IV APN 0.0076 0.0294 0.0739
Trypanosoma cruzi JmjC domain, hydroxylase, putative 0.0044 0.0121 0.065
Brugia malayi Nuclear hormone receptor family member nhr-41 0.0022 0.0008 0.0019
Loa Loa (eye worm) hypothetical protein 0.0036 0.0084 0.0166
Echinococcus multilocularis intestinal type alkaline phosphatase 0.0172 0.0796 0.0794
Loa Loa (eye worm) hypothetical protein 0.0028 0.004 0.0076
Trypanosoma cruzi DNA polymerase kappa, putative 0.0065 0.0236 0.1392
Echinococcus granulosus caspase 2 0.0028 0.004 0.0038
Brugia malayi F/Y-rich N-terminus family protein 0.0032 0.0059 0.0135
Echinococcus granulosus importin subunit beta 1 0.0089 0.0358 0.0356
Mycobacterium ulcerans fatty-acid-CoA ligase 0.0036 0.0084 0.0385
Toxoplasma gondii poly(ADP-ribose) polymerase catalytic domain-containing protein 0.0294 0.1432 0.3607
Echinococcus multilocularis arachidonate 5 lipoxygenase 0.0122 0.0533 0.0531
Echinococcus multilocularis jumonji domain containing protein 0.0087 0.035 0.0347
Trypanosoma cruzi cytochrome P450, putative 0.0035 0.0076 0.0357
Brugia malayi jmjC domain containing protein 0.0264 0.1276 0.2903
Echinococcus multilocularis peptidyl glycine alpha amidating monooxygenase 0.0497 0.2498 0.2496
Loa Loa (eye worm) intermediate filament protein 0.0142 0.0635 0.13
Brugia malayi Copper type II ascorbate-dependent monooxygenase, C-terminal domain containing protein 0.0245 0.1176 0.2674
Echinococcus multilocularis TGF beta signal transducer SmadC 0.0026 0.0028 0.0026
Toxoplasma gondii inositol(myo)-1(or 4)-monophosphatase 2, putative 0.0039 0.0098 0.0248
Echinococcus multilocularis snurportin 1 0.0948 0.4861 0.486
Plasmodium falciparum metacaspase 1 0.0028 0.004 0.0466
Schistosoma mansoni retinoid-x-receptor (RXR) 0.0022 0.0008 0.0011
Mycobacterium tuberculosis Probable aldehyde dehydrogenase 0.0066 0.0239 0.1475
Schistosoma mansoni poly [ADP-ribose] polymerase 0.0155 0.0706 0.0919
Loa Loa (eye worm) hypothetical protein 0.0497 0.2498 0.5134
Loa Loa (eye worm) poly(ADP-ribose) polymerase 0.0111 0.0476 0.0974
Echinococcus granulosus cathepsin b 0.0141 0.0632 0.063
Toxoplasma gondii cathepsin B 0.0049 0.0151 0.0381
Schistosoma mansoni nuclear hormone receptor nor-1/nor-2 0.0022 0.0008 0.0011
Mycobacterium tuberculosis Possible conserved lipoprotein LpqK 0.0039 0.0098 0.0486
Mycobacterium tuberculosis Probable fatty-acid-CoA ligase FadD2 (fatty-acid-CoA synthetase) (fatty-acid-CoA synthase) 0.0049 0.0148 0.0838
Mycobacterium leprae conserved hypothetical protein 0.0039 0.0098 0.0435
Echinococcus multilocularis neuropeptide s receptor 0.1928 1 1
Echinococcus multilocularis bloom syndrome protein 0.0086 0.0342 0.034
Trichomonas vaginalis Clan CD, family C14, metacaspase-like cysteine peptidase 0.0028 0.004 0.0075
Echinococcus granulosus ATP dependent DNA helicase Q5 0.0048 0.0143 0.014
Loa Loa (eye worm) DOMON domain-containing protein 0.0095 0.0391 0.0799
Schistosoma mansoni hypothetical protein 0.0948 0.4861 0.6326
Onchocerca volvulus Steroid hormone receptor family member cnr14 homolog 0.0022 0.0008 0.0012
Echinococcus multilocularis dna polymerase eta 0.0036 0.0082 0.008
Schistosoma mansoni nuclear receptor 2DBD-gamma 0.0022 0.0008 0.0011
Entamoeba histolytica recQ family DNA helicase 0.0024 0.002 0.0057
Entamoeba histolytica recQ family helicase, putative 0.0056 0.0184 0.0587
Loa Loa (eye worm) hypothetical protein 0.0024 0.002 0.0035
Leishmania major DNA polymerase eta, putative 0.0036 0.0082 0.0348
Mycobacterium ulcerans acyl-CoA synthetase 0.0049 0.0148 0.0838
Loa Loa (eye worm) hypothetical protein 0.0051 0.0162 0.0328
Schistosoma mansoni lipoxygenase 0.0085 0.0341 0.0443
Leishmania major heat shock protein 83-1 0.0034 0.0073 0.0288
Echinococcus granulosus heat shock protein heat shock protein 90 alpha 0.0027 0.0036 0.0034
Mycobacterium tuberculosis Probable chain -fatty-acid-CoA ligase FadD13 (fatty-acyl-CoA synthetase) 0.0049 0.0148 0.0838
Echinococcus multilocularis Glutamate receptor, ionotropic kainate 2 0.004 0.0104 0.0102
Loa Loa (eye worm) RNA recognition domain-containing protein domain-containing protein 0.0067 0.0246 0.0499
Entamoeba histolytica glycosyl hydrolase, family 31 protein 0.0038 0.0094 0.0294
Schistosoma mansoni blooms syndrome DNA helicase 0.0024 0.002 0.0026
Trichomonas vaginalis Citrate lyase beta chain, putative 0.0026 0.0029 0.0052
Schistosoma mansoni subfamily C14A unassigned peptidase (C14 family) 0.0028 0.004 0.0052
Echinococcus multilocularis gcn5proteinral control of amino acid synthesis 0.0164 0.075 0.0748
Echinococcus granulosus Smad4 0.0026 0.0028 0.0026
Trypanosoma brucei heat shock protein, putative 0.0034 0.0073 0.0466
Mycobacterium tuberculosis Probable fatty-acid-CoA ligase FadD5 (fatty-acid-CoA synthetase) (fatty-acid-CoA synthase) 0.0034 0.0073 0.0312
Brugia malayi ATP-dependent DNA helicase, RecQ family protein 0.0048 0.0143 0.0325
Loa Loa (eye worm) ATP-dependent DNA helicase 0.0048 0.0143 0.0288
Loa Loa (eye worm) hepatopoietin HPO2 0.0034 0.0072 0.0142
Trypanosoma cruzi tyrosyl-DNA Phosphodiesterase (Tdp1), putative 0.007 0.0259 0.1543
Brugia malayi Nuclear hormone receptor family member nhr-25 0.0022 0.0008 0.0019
Trichomonas vaginalis alpha-glucosidase, putative 0.0038 0.0094 0.0181
Trichomonas vaginalis alpha-glucosidase, putative 0.0038 0.0094 0.0181
Echinococcus granulosus nuclear receptor 2DBD gamma 0.0022 0.0008 0.0006
Echinococcus granulosus JmjC domain containing protein 4 0.0044 0.0121 0.0118
Loa Loa (eye worm) hypothetical protein 0.0028 0.004 0.0076
Loa Loa (eye worm) hypothetical protein 0.0048 0.0143 0.0288
Brugia malayi jmjC domain containing protein 0.0044 0.0121 0.0275
Echinococcus granulosus inositol monophosphatase 1 0.0039 0.0098 0.0096
Echinococcus granulosus dna polymerase eta 0.0036 0.0082 0.008
Leishmania major importin beta-1 subunit, putative 0.0072 0.027 0.1565
Echinococcus multilocularis dna polymerase kappa 0.0065 0.0236 0.0234
Toxoplasma gondii PHD-finger domain-containing protein 0.0063 0.0221 0.0557
Mycobacterium tuberculosis Probable conserved lipoprotein 0.0039 0.0098 0.0486
Toxoplasma gondii histone lysine acetyltransferase GCN5-B 0.0052 0.0163 0.0411
Echinococcus granulosus poly (ADP ribose) polymerase 0.0044 0.0123 0.012
Trichomonas vaginalis Clan CD, family C14, metacaspase-like cysteine peptidase 0.0028 0.004 0.0075
Echinococcus multilocularis lysine specific demethylase 5A 0.0215 0.1019 0.1017
Echinococcus multilocularis endonuclease exonuclease phosphatase 0.0207 0.0978 0.0976
Toxoplasma gondii ICE family protease (caspase) p20 domain-containing protein 0.0028 0.004 0.0101
Schistosoma mansoni glutamate receptor kainate 0.004 0.0104 0.0136
Echinococcus multilocularis caspase 3, apoptosis cysteine peptidase 0.0028 0.004 0.0038
Schistosoma mansoni glutamate receptor NMDA 0.004 0.0104 0.0136
Brugia malayi jmjC domain containing protein 0.0293 0.1427 0.3245
Giardia lamblia PHD finger protein 15 0.0063 0.0221 0.0604
Trypanosoma brucei inositol-1(or 4)-monophosphatase 1, putative 0.0039 0.0098 0.0627
Trypanosoma cruzi metacaspase 5, putative 0.0028 0.004 0.0128
Brugia malayi Animal haem peroxidase family protein 0.0051 0.0162 0.0369
Mycobacterium ulcerans acyl-CoA synthetase 0.0049 0.0148 0.0838
Loa Loa (eye worm) cytochrome P450 family protein 0.0035 0.0076 0.0149
Trichomonas vaginalis heat shock protein, putative 0.0021 0.0003 0.0002
Mycobacterium ulcerans extragenic suppressor protein SuhB 0.0039 0.0098 0.0488
Trypanosoma brucei isocitrate dehydrogenase, putative 0.0067 0.0242 0.1542
Schistosoma mansoni peroxidasin 0.0051 0.0162 0.0211
Brugia malayi WGR domain containing protein 0.0155 0.0706 0.1607
Schistosoma mansoni aldehyde dehydrogenase 0.0066 0.0239 0.0311
Brugia malayi Glycosyl hydrolases family 31 protein 0.0038 0.0094 0.0213
Loa Loa (eye worm) hypothetical protein 0.0022 0.0008 0.0011
Trypanosoma brucei DNA polymerase IV, putative 0.0058 0.0198 0.126
Leishmania major lipophosphoglycan biosynthetic protein, putative,heat shock protein 90, putative,glucose regulated protein 94, putative 0.0027 0.0036 0.005
Entamoeba histolytica hypothetical protein 0.0072 0.027 0.0865
Plasmodium falciparum FAD-linked sulfhydryl oxidase ERV1, putative 0.0034 0.0072 0.0838
Entamoeba histolytica hypothetical protein 0.0038 0.0093 0.0293
Trypanosoma brucei metacaspase 5, putative 0.0028 0.004 0.0255
Loa Loa (eye worm) hypothetical protein 0.0051 0.0162 0.0328
Echinococcus multilocularis histone lysine N methyltransferase SETMAR 0.0124 0.0544 0.0542
Echinococcus granulosus transcription factor Dp 1 0.004 0.0105 0.0102
Trypanosoma brucei heat shock protein, putative 0.0034 0.0073 0.0466
Entamoeba histolytica heat shock protein 90, putative 0.0034 0.0073 0.0229
Echinococcus multilocularis glutamate receptor 2 0.004 0.0104 0.0102
Schistosoma mansoni histone-lysine n-methyltransferase setb1 0.0124 0.0544 0.0708
Echinococcus granulosus intestinal type alkaline phosphatase 0.0172 0.0796 0.0794
Schistosoma mansoni smad1 5 8 and 0.0026 0.0028 0.0037
Brugia malayi Pre-SET motif family protein 0.0859 0.4397 1
Toxoplasma gondii hypothetical protein 0.0025 0.0025 0.0064
Schistosoma mansoni glutamate receptor kainate 0.004 0.0104 0.0136
Echinococcus granulosus caspase 8 0.0028 0.004 0.0038
Brugia malayi Bloom's syndrome protein homolog 0.0086 0.0342 0.0778
Echinococcus granulosus FTZ F1 nuclear receptor protein 0.0022 0.0008 0.0006
Brugia malayi RNA recognition motif domain containing protein 0.0067 0.0246 0.0558
Toxoplasma gondii histone lysine demethylase JMJD6a 0.0044 0.0121 0.0305
Echinococcus granulosus glutamate NMDA receptor subunit 0.004 0.0104 0.0102
Mycobacterium tuberculosis Probable hydrolase 0.0039 0.0098 0.0486
Loa Loa (eye worm) hypothetical protein 0.0497 0.2498 0.5134
Leishmania major heat shock protein 83-1 0.0034 0.0073 0.0288
Leishmania major hypothetical protein, conserved 0.0034 0.0072 0.0281
Schistosoma mansoni steroid hormone receptor ad4bp 0.0022 0.0008 0.0011
Toxoplasma gondii isocitrate dehydrogenase 0.0067 0.0242 0.061
Mycobacterium ulcerans aldehyde dehydrogenase 0.0066 0.0239 0.1475
Brugia malayi Bromodomain containing protein 0.0084 0.0334 0.0759
Loa Loa (eye worm) hypothetical protein 0.0022 0.0008 0.0011
Loa Loa (eye worm) heat shock protein 90 0.0034 0.0073 0.0144
Brugia malayi follicle stimulating hormone receptor 0.0238 0.1143 0.2599
Brugia malayi beta-lactamase 0.0039 0.0098 0.0223
Schistosoma mansoni coup transcription factor 0.0022 0.0008 0.0011
Echinococcus multilocularis FAD linked sulfhydryl oxidase ALR 0.0034 0.0072 0.007
Loa Loa (eye worm) MH2 domain-containing protein 0.0026 0.0028 0.0052
Plasmodium vivax acyl-CoA synthetase, putative 0.0036 0.0084 0.0973
Mycobacterium tuberculosis Probable endonuclease IV End (endodeoxyribonuclease IV) (apurinase) 0.0076 0.0294 0.1854
Leishmania major hypothetical protein, conserved 0.0032 0.0061 0.0207
Schistosoma mansoni Smad4 0.0026 0.0028 0.0037
Echinococcus multilocularis diuretic hormone 44 receptor GPRdih2 0.0152 0.0689 0.0687
Echinococcus granulosus citrate lyase subunit beta protein 0.0026 0.0029 0.0026
Loa Loa (eye worm) hypothetical protein 0.048 0.241 0.4955
Loa Loa (eye worm) blistered cuticle protein 3 0.0051 0.0162 0.0328
Schistosoma mansoni glutamate receptor AMPA 0.004 0.0104 0.0136
Trypanosoma cruzi heat shock protein 90, putative 0.0034 0.0073 0.0342
Brugia malayi MH1 domain containing protein 0.0026 0.0028 0.0065
Plasmodium falciparum apurinic/apyrimidinic endonuclease Apn1, putative 0.0076 0.0294 0.3411
Onchocerca volvulus 0.0039 0.0098 0.0191
Plasmodium vivax hypothetical protein, conserved 0.0039 0.0098 0.1141
Brugia malayi GTP-binding regulatory protein Gs alpha-S chain, putative 0.0098 0.0406 0.0923
Loa Loa (eye worm) cytoplasmic intermediate filament protein 0.0076 0.029 0.0591
Schistosoma mansoni peptidylglycine monooxygenase 0.0497 0.2498 0.325
Echinococcus multilocularis histone lysine methyltransferase setb histone lysine methyltransferase eggless 0.016 0.0731 0.0729
Echinococcus granulosus bromodomain adjacent to zinc finger domain 0.0075 0.0287 0.0285
Brugia malayi Hypothetical 52.5 kDa protein ZK945.1 in chromosome II, putative 0.0039 0.0098 0.0223
Onchocerca volvulus Alhambra homolog 0.0063 0.0221 0.0436
Leishmania major mitochondrial DNA polymerase beta 0.032 0.1571 1
Trichomonas vaginalis penicillin-binding protein, putative 0.0039 0.0098 0.0191
Loa Loa (eye worm) hypothetical protein 0.0039 0.0098 0.0196
Trypanosoma brucei mitochondrial DNA polymerase beta 0.032 0.1571 1
Trypanosoma brucei DNA polymerase kappa, putative 0.0032 0.0062 0.0393
Entamoeba histolytica hypothetical protein 0.0044 0.0123 0.0389
Echinococcus multilocularis FTZ F1 alpha 0.0022 0.0008 0.0006
Trypanosoma brucei isocitrate dehydrogenase [NADP], mitochondrial precursor, putative 0.0067 0.0242 0.1542
Onchocerca volvulus 0.0051 0.0162 0.0318
Plasmodium vivax heat shock protein 86, putative 0.0034 0.0073 0.0851
Trypanosoma brucei importin beta-1 subunit, putative 0.0089 0.0358 0.228
Loa Loa (eye worm) tyrosyl-DNA phosphodiesterase 0.007 0.0259 0.0528
Trypanosoma brucei glucosidase, putative 0.0038 0.0094 0.0595
Brugia malayi C2-HC type zinc finger protein C.e-MyT1 0.0058 0.0194 0.0442
Echinococcus multilocularis cytoplasmic intermediate filament protein 0.0068 0.0251 0.0248
Trypanosoma brucei DNA polymerase kappa, putative 0.0043 0.0121 0.0768
Trypanosoma cruzi DNA polymerase eta, putative 0.0036 0.0082 0.0401
Loa Loa (eye worm) cathepsin B 0.0049 0.0151 0.0305
Echinococcus multilocularis aldehyde dehydrogenase, mitochondrial 0.0066 0.0239 0.0237
Echinococcus granulosus polycomb protein SCMH1 0.0051 0.0158 0.0155
Echinococcus granulosus jumonji domain containing protein 0.0087 0.035 0.0347
Brugia malayi PHD-finger family protein 0.0058 0.0195 0.0444
Brugia malayi Intermediate filament tail domain containing protein 0.0142 0.0635 0.1444
Loa Loa (eye worm) hypothetical protein 0.0051 0.0162 0.0328
Onchocerca volvulus Cell death protein 3 homolog 0.0028 0.004 0.0075
Echinococcus multilocularis Jumonji, AT rich interactive domain 1B 0.014 0.0627 0.0624
Toxoplasma gondii ATP-dependent DNA helicase, RecQ family protein 0.0054 0.0173 0.0437
Schistosoma mansoni smad 0.0026 0.0028 0.0037
Toxoplasma gondii PLU-1 family protein 0.0043 0.0121 0.0304
Schistosoma mansoni aldehyde dehydrogenase 0.0066 0.0239 0.0311
Giardia lamblia DINP protein human, muc B family 0.0043 0.0121 0.0275
Brugia malayi acetyltransferase, GNAT family protein 0.0164 0.075 0.1705
Echinococcus granulosus histone acetyltransferase MYST2 0.0058 0.0194 0.0192
Brugia malayi hypothetical protein 0.0132 0.0585 0.1331
Onchocerca volvulus 0.0051 0.0162 0.0318
Loa Loa (eye worm) hypothetical protein 0.0037 0.0086 0.0171
Schistosoma mansoni intermediate filament proteins 0.0142 0.0635 0.0826
Schistosoma mansoni lamin 0.0142 0.0635 0.0826
Echinococcus granulosus Basic leucine zipper bZIP transcription 0.0038 0.0093 0.0091
Trichomonas vaginalis conserved hypothetical protein 0.0028 0.004 0.0075
Trichomonas vaginalis fructose-bisphosphate aldolase, putative 0.0611 0.3094 0.6164
Trypanosoma cruzi 2,4-dihydroxyhept-2-ene-1,7-dioic acid aldolase, putative 0.0026 0.0029 0.0055
Trypanosoma brucei importin beta-1 subunit, putative 0.0089 0.0358 0.228
Mycobacterium ulcerans heat shock protein 90 0.0027 0.0036 0.0054
Echinococcus multilocularis heat shock protein 90 0.0027 0.0036 0.0034
Onchocerca volvulus 0.0124 0.0544 0.1079
Chlamydia trachomatis enoyl-acyl-carrier protein reductase 0.0185 0.0861 1
Trypanosoma cruzi hypothetical protein, conserved 0.0038 0.0094 0.0473
Echinococcus granulosus caspase 0.0028 0.004 0.0038
Schistosoma mansoni hypothetical protein 0.0063 0.0221 0.0288
Plasmodium vivax hypothetical protein, conserved 0.0063 0.0221 0.2569
Trypanosoma brucei DNA polymerase kappa, putative 0.0065 0.0236 0.1503
Echinococcus granulosus PHD finger protein rhinoceros 0.0063 0.0221 0.0219
Trypanosoma cruzi hypothetical protein, conserved 0.0039 0.0098 0.0503
Leishmania major heat shock protein 83-1 0.0034 0.0073 0.0288
Mycobacterium tuberculosis Probable chaperone protein HtpG (heat shock protein) (HSP90 family protein) (high temperature protein G) 0.0027 0.0036 0.0054
Mycobacterium ulcerans esterase/lipase LipP 0.0039 0.0098 0.0486
Echinococcus multilocularis glutamate (NMDA) receptor subunit 0.004 0.0104 0.0102
Schistosoma mansoni sex comb on midleg homolog 0.0051 0.0158 0.0205
Trypanosoma brucei mitochondrial DNA polymerase beta-PAK 0.0151 0.0687 0.4373
Loa Loa (eye worm) hypothetical protein 0.016 0.0731 0.1499
Toxoplasma gondii aldehyde dehydrogenase 0.0066 0.0239 0.0603
Echinococcus multilocularis neutral alpha glucosidase AB 0.0038 0.0094 0.0091
Plasmodium vivax metacaspase 1, putative 0.0028 0.004 0.0466
Echinococcus granulosus heat shock protein 90 0.0034 0.0073 0.0071
Onchocerca volvulus 0.01 0.0416 0.0825
Echinococcus granulosus jumonji domain containing 1A 0.0044 0.0121 0.0118
Schistosoma mansoni glutamate receptor NMDA 0.004 0.0104 0.0136
Mycobacterium tuberculosis Probable exodeoxyribonuclease III protein XthA (exonuclease III) (EXO III) (AP endonuclease VI) 0.0039 0.0096 0.0467
Trypanosoma cruzi metacaspase, putative 0.0028 0.004 0.0128
Trypanosoma cruzi heat shock protein 85, putative 0.0027 0.0036 0.0105
Trypanosoma cruzi DNA polymerase beta thumb, putative 0.0045 0.0129 0.0699
Trypanosoma brucei poly(adp-ribose) polymerase 0.0155 0.0706 0.4498
Echinococcus multilocularis PHD finger protein rhinoceros 0.0063 0.0221 0.0219
Schistosoma mansoni poly [ADP-ribose] polymerase 0.0134 0.0597 0.0776
Trichomonas vaginalis Clan CD, family C14, metacaspase-like cysteine peptidase 0.0028 0.004 0.0075
Echinococcus granulosus glutamate receptor 2 0.004 0.0104 0.0102
Brugia malayi Pre-SET motif family protein 0.0124 0.0544 0.1237
Schistosoma mansoni alpha glucosidase 0.0038 0.0094 0.0122
Toxoplasma gondii ABC1 family protein 0.0039 0.0098 0.0247
Echinococcus multilocularis lysosomal alpha glucosidase 0.0173 0.0798 0.0796
Mycobacterium ulcerans long-chain-fatty-acid--CoA ligase 0.0049 0.0148 0.0838
Loa Loa (eye worm) hypothetical protein 0.0022 0.0008 0.0011
Trypanosoma brucei heat shock protein, putative 0.0034 0.0073 0.0466
Mycobacterium tuberculosis Inositol-1-monophosphatase SuhB 0.0035 0.0077 0.0337
Leishmania major tyrosyl-DNA phosphodiesterase 1 0.007 0.0259 0.1496
Trypanosoma brucei metacaspase 0.0028 0.004 0.0255
Trypanosoma brucei metacaspase MCA3 0.0028 0.004 0.0255
Trypanosoma cruzi apurinic/apyrimidinic endonuclease 0.0039 0.0096 0.0486
Loa Loa (eye worm) hypothetical protein 0.0132 0.0585 0.1198
Trypanosoma brucei DNA polymerase kappa, putative 0.0065 0.0236 0.1503
Loa Loa (eye worm) nuclear hormone receptor family member nhr-49 0.0022 0.0008 0.0011
Echinococcus granulosus Glutamate receptor ionotropic kainate 2 0.004 0.0104 0.0102
Mycobacterium ulcerans long-chain fatty-acid CoA ligase 0.0049 0.0148 0.0838
Brugia malayi MH2 domain containing protein 0.0026 0.0028 0.0065
Echinococcus granulosus Nuclear hormone receptor family member nhr 41 0.0022 0.0008 0.0006
Plasmodium falciparum isocitrate dehydrogenase [NADP], mitochondrial 0.0067 0.0242 0.2815
Chlamydia trachomatis endonuclease IV 0.0076 0.0294 0.2701
Trypanosoma cruzi heat shock protein 85, putative 0.0034 0.0073 0.0342
Trypanosoma brucei JmjC domain, hydroxylase, putative 0.0044 0.0121 0.077
Toxoplasma gondii exonuclease III APE 0.0039 0.0096 0.0241
Loa Loa (eye worm) MBCTL1 0.0058 0.0194 0.0394
Schistosoma mansoni rab geranylgeranyl transferase alpha subunit 0.0036 0.0082 0.0107
Trichomonas vaginalis conserved hypothetical protein 0.0028 0.004 0.0075
Trypanosoma brucei DNA polymerase kappa, putative 0.0032 0.0062 0.0393
Leishmania major 4-coumarate:coa ligase-like protein 0.0049 0.0148 0.0776
Schistosoma mansoni tankyrase 0.0021 0.0003 0.0004
Onchocerca volvulus 0.0051 0.0162 0.0318
Trichomonas vaginalis heat shock protein, putative 0.0027 0.0036 0.0068
Trichomonas vaginalis neutral alpha-glucosidase ab precursor, putative 0.0038 0.0094 0.0181
Plasmodium falciparum endoplasmin, putative 0.0021 0.0003 0.004
Leishmania major heat shock protein 83-1 0.0034 0.0073 0.0288
Trypanosoma cruzi JmjC domain, hydroxylase, putative 0.0044 0.0121 0.065
Toxoplasma gondii cytochrome p450 superfamily protein 0.0778 0.397 1
Echinococcus granulosus Jumonji AT rich interactive domain 1B 0.014 0.0627 0.0624
Schistosoma mansoni sex comb on midleg homolog 0.0051 0.0158 0.0205
Echinococcus multilocularis glutamate receptor 2 0.004 0.0104 0.0102
Trichomonas vaginalis D-aminoacylase, putative 0.0039 0.0098 0.0191
Loa Loa (eye worm) hypothetical protein 0.0089 0.0358 0.0731
Plasmodium vivax AP endonuclease (DNA-[apurinic or apyrimidinic site] lyase), putative 0.0039 0.0096 0.111
Toxoplasma gondii PHD-finger domain-containing protein 0.0063 0.0221 0.0557
Loa Loa (eye worm) hypothetical protein 0.0039 0.0098 0.0196
Echinococcus multilocularis terminal deoxycytidyl transferase rev1 0.0036 0.0082 0.008
Schistosoma mansoni family S12 unassigned peptidase (S12 family) 0.0039 0.0098 0.0128
Onchocerca volvulus Bile acid receptor homolog 0.0022 0.0008 0.0012
Leishmania major ATP-dependent DEAD/H DNA helicase recQ, putative 0.0056 0.0184 0.1007
Loa Loa (eye worm) pre-SET domain-containing protein family protein 0.0859 0.4397 0.9045
Echinococcus granulosus dna polymerase kappa 0.0065 0.0236 0.0234
Trypanosoma brucei unspecified product 0.0025 0.0024 0.015
Brugia malayi Glutamate receptor 2 precursor 0.004 0.0104 0.0237
Mycobacterium tuberculosis Probable fatty-acid-CoA ligase FadD7 (fatty-acid-CoA synthetase) (fatty-acid-CoA synthase) 0.0034 0.0073 0.0312
Schistosoma mansoni cathepsin B-like peptidase (C01 family) 0.0141 0.0632 0.0823
Echinococcus multilocularis cathepsin b 0.0141 0.0632 0.063
Loa Loa (eye worm) hypothetical protein 0.0139 0.0621 0.1272
Loa Loa (eye worm) jmjC domain-containing protein 0.0129 0.0571 0.1168
Echinococcus multilocularis Glutamate receptor, ionotropic kainate 2 0.004 0.0104 0.0102
Echinococcus granulosus ecdysone induced protein 78C 0.0022 0.0008 0.0006
Trichomonas vaginalis myo inositol monophosphatase, putative 0.0039 0.0098 0.0191
Loa Loa (eye worm) exodeoxyribonuclease III family protein 0.0039 0.0096 0.019
Trypanosoma cruzi ISWI complex protein 0.0032 0.0061 0.0262
Loa Loa (eye worm) hypothetical protein 0.0022 0.0008 0.0011
Entamoeba histolytica poly(ADP-ribose) polymerase, putative 0.0283 0.1374 0.4435
Schistosoma mansoni zinc finger protein 0.0047 0.0137 0.0178
Echinococcus multilocularis lamin 0.0142 0.0635 0.0633
Trypanosoma brucei tyrosyl-DNA Phosphodiesterase (Tdp1), putative 0.007 0.0259 0.1652
Echinococcus multilocularis transcription factor Dp 1 0.004 0.0105 0.0102
Trichomonas vaginalis myo inositol monophosphatase, putative 0.0039 0.0098 0.0191
Trypanosoma brucei DNA polymerase IV, putative 0.0065 0.0236 0.1503
Echinococcus multilocularis mothers against decapentaplegic 5 0.0026 0.0028 0.0026
Plasmodium falciparum enoyl-acyl carrier reductase 0.0185 0.0861 1
Trypanosoma cruzi ATP-dependent DEAD/H DNA helicase recQ, putative 0.0056 0.0184 0.1057
Plasmodium falciparum metacaspase-like protein 0.0028 0.004 0.0466
Mycobacterium tuberculosis Conserved protein 0.0039 0.0098 0.0486
Echinococcus multilocularis poly (adp ribose) polymerase 2 0.0155 0.0706 0.0704
Echinococcus granulosus FTZ F1 alpha 0.0022 0.0008 0.0006
Schistosoma mansoni transcription factor LCR-F1 0.0038 0.0093 0.0121
Echinococcus multilocularis intestinal type alkaline phosphatase 1 0.0172 0.0796 0.0794
Schistosoma mansoni hypothetical protein 0.0315 0.1545 0.201
Loa Loa (eye worm) hypothetical protein 0.0039 0.0098 0.0196
Loa Loa (eye worm) beta-lactamase 0.0039 0.0098 0.0196
Trichomonas vaginalis esterase, putative 0.0039 0.0098 0.0191
Brugia malayi photoreceptor-specific nuclear receptor 0.0022 0.0008 0.0019
Trypanosoma cruzi poly(ADP-ribose) polymerase, putative 0.0155 0.0706 0.4426
Mycobacterium ulcerans hypothetical protein 0.0039 0.0098 0.0486
Brugia malayi mbt repeat family protein 0.0051 0.0158 0.0359
Schistosoma mansoni DNA helicase recq5 0.0048 0.0143 0.0186
Schistosoma mansoni zinc finger protein 0.0032 0.0061 0.0079
Echinococcus granulosus endonuclease exonuclease phosphatase 0.0207 0.0978 0.0976
Mycobacterium leprae NADH-DEPENDENT ENOYL-[ACYL-CARRIER-PROTEIN] REDUCTASE INHA (NADH-DEPENDENT ENOYL-ACP REDUCTASE) 0.0185 0.0861 0.5802
Onchocerca volvulus Polycomb protein Sfmbt homolog 0.0051 0.0158 0.0309
Schistosoma mansoni phosphatidylserine receptor 0.0044 0.0121 0.0157
Giardia lamblia Cathepsin B precursor 0.0049 0.0151 0.0375
Echinococcus granulosus phd:f box containing protein 0.0044 0.0121 0.0118
Brugia malayi Nuclear hormone receptor family member nhr-1 0.0022 0.0008 0.0019
Mycobacterium tuberculosis Probable esterase/lipase LipP 0.0039 0.0098 0.0486
Trypanosoma cruzi DNA repair protein, putative 0.0037 0.0086 0.0425
Echinococcus granulosus nuclear factor of activated T cells 5 0.0072 0.027 0.0267
Loa Loa (eye worm) hypothetical protein 0.0076 0.0294 0.0598
Schistosoma mansoni peptidyl-glycine monooxygenase 0.0497 0.2498 0.325
Schistosoma mansoni TGF-beta signal transducer Smad2 0.0026 0.0028 0.0037
Leishmania major heat shock protein 83-1 0.0034 0.0073 0.0288
Echinococcus multilocularis isocitrate dehydrogenase 0.0067 0.0242 0.024
Mycobacterium leprae PROBABLE FATTY-ACID-CoA LIGASE FADD7 (FATTY-ACID-CoA SYNTHETASE) (FATTY-ACID-CoA SYNTHASE) 0.0049 0.0148 0.0788
Loa Loa (eye worm) latrophilin receptor protein 2 0.0152 0.0689 0.1412
Loa Loa (eye worm) hypothetical protein 0.0049 0.0148 0.0299
Mycobacterium tuberculosis Fatty-acid-AMP ligase FadD30 (fatty-acid-AMP synthetase) (fatty-acid-AMP synthase) 0.0036 0.0084 0.0385
Loa Loa (eye worm) animal heme peroxidase 0.0051 0.0162 0.0328
Plasmodium falciparum JmjC domain-containing protein, putative 0.0066 0.0237 0.275
Brugia malayi Cell death protein 3 precursor 0.0028 0.004 0.0091
Toxoplasma gondii enoyl-acyl carrier reductase ENR 0.0185 0.0861 0.2168
Plasmodium vivax SET domain protein, putative 0.0124 0.0544 0.6322
Echinococcus multilocularis inositol monophosphatase 1 0.0039 0.0098 0.0096
Schistosoma mansoni photoreceptor-specific nuclear receptor related 0.0022 0.0008 0.0011
Echinococcus multilocularis guanine nucleotide binding protein G(s) subunit 0.0098 0.0406 0.0404
Loa Loa (eye worm) endoplasmin 0.0034 0.0073 0.0144
Onchocerca volvulus Peroxidasin homolog 0.0051 0.0162 0.0318
Brugia malayi Ligand-binding domain of nuclear hormone receptor family protein 0.0022 0.0008 0.0019
Loa Loa (eye worm) hypothetical protein 0.0157 0.0714 0.1462
Brugia malayi Nuclear hormone receptor family member nhr-14 0.0022 0.0008 0.0019
Trichomonas vaginalis cat eye syndrome critical region protein 2, cscr2, putative 0.0052 0.0163 0.032
Schistosoma mansoni methyl-cpg binding protein mbd 0.0036 0.008 0.0104
Echinococcus granulosus Glutamate receptor ionotropic kainate 2 0.004 0.0104 0.0102
Echinococcus multilocularis NADP dependent isocitrate dehydrogenase 0.0067 0.0242 0.024
Toxoplasma gondii ICE family protease (caspase) p20 domain-containing protein 0.0028 0.004 0.0101
Brugia malayi Animal haem peroxidase family protein 0.0051 0.0162 0.0369
Schistosoma mansoni inositol monophosphatase 0.0039 0.0098 0.0128
Giardia lamblia Fructose-bisphosphate aldolase 0.0611 0.3094 1
Echinococcus multilocularis musashi 0.0142 0.0635 0.0633
Loa Loa (eye worm) hypothetical protein 0.0051 0.0162 0.0328
Echinococcus granulosus intestinal type alkaline phosphatase 1 0.0172 0.0796 0.0794
Echinococcus granulosus cytoplasmic intermediate filament protein 0.0068 0.0251 0.0248
Mycobacterium ulcerans DNA polymerase IV 0.0065 0.0236 0.1451
Trypanosoma brucei DNA polymerase kappa, putative 0.0065 0.0236 0.1503
Echinococcus granulosus fetal alzheimer antigen falz 0.0049 0.0149 0.0146
Schistosoma mansoni hypothetical protein 0.0043 0.0119 0.0155
Schistosoma mansoni hypothetical protein 0.0032 0.0061 0.0079
Trypanosoma brucei cytochrome P450, putative 0.0035 0.0076 0.0481
Brugia malayi TAR-binding protein 0.0067 0.0246 0.0558
Trichomonas vaginalis Clan CD, family C14, metacaspase-like cysteine peptidase 0.0028 0.004 0.0075
Onchocerca volvulus Protein ultraspiracle homolog 0.0022 0.0008 0.0012
Loa Loa (eye worm) glutamate receptor 2 0.004 0.0104 0.0209
Mycobacterium ulcerans exodeoxyribonuclease III protein XthA 0.0039 0.0096 0.0467
Mycobacterium ulcerans fatty-acid-CoA ligase 0.0049 0.0148 0.0838
Entamoeba histolytica acyl-CoA synthetase, putative 0.0049 0.0148 0.0472
Trypanosoma brucei DNA polymerase beta thumb, putative 0.0045 0.0129 0.0819
Mycobacterium leprae possible inositol monophosphatase SubH (IMPase) (inositol-1-phosphatase) (I-1-Pase ). 0.0035 0.0077 0.0285
Entamoeba histolytica hypothetical protein 0.0038 0.0093 0.0293
Giardia lamblia Sgs1 DNA helicase, putative 0.0048 0.0143 0.0348
Plasmodium falciparum AP endonuclease (DNA-[apurinic or apyrimidinic site] lyase), putative 0.0039 0.0096 0.111
Loa Loa (eye worm) hypothetical protein 0.0152 0.0689 0.1412
Leishmania major apurinic/apyrimidinic endonuclease-redox protein 0.0039 0.0096 0.0433
Giardia lamblia Cathepsin B precursor 0.0049 0.0151 0.0375
Trypanosoma cruzi tyrosyl-DNA Phosphodiesterase (Tdp1), putative 0.007 0.0259 0.1543
Trypanosoma brucei hypothetical protein, conserved 0.0039 0.0098 0.0625
Echinococcus multilocularis nuclear factor of activated T cells 5 0.0072 0.027 0.0267
Trichomonas vaginalis conserved hypothetical protein 0.0028 0.004 0.0075
Echinococcus multilocularis histone lysine N methyltransferase NSD3 0.0039 0.0098 0.0096
Brugia malayi Animal haem peroxidase family protein 0.0051 0.0162 0.0369
Schistosoma mansoni DNA polymerase eta 0.0036 0.0082 0.0107
Loa Loa (eye worm) hypothetical protein 0.0036 0.0084 0.0166
Trypanosoma cruzi Poly(ADP-ribose) polymerase and DNA-Ligase Zn-finger region/Zinc-finger (CX5CX6HX5H) motif containing protein, putative 0.0037 0.0086 0.0425
Schistosoma mansoni ran 0.0065 0.0235 0.0306
Echinococcus multilocularis nuclear receptor 2DBD gamma 0.0022 0.0008 0.0006
Echinococcus multilocularis peregrin 0.0082 0.032 0.0318
Trichomonas vaginalis fructose-bisphosphate aldolase, putative 0.0611 0.3094 0.6164
Brugia malayi intermediate filament protein 0.0142 0.0635 0.1444
Trichomonas vaginalis ran, putative 0.0065 0.0235 0.0464
Echinococcus granulosus arachidonate 5 lipoxygenase 0.0122 0.0533 0.0531
Loa Loa (eye worm) hypothetical protein 0.0051 0.0158 0.0318
Schistosoma mansoni endoplasmin 0.0034 0.0073 0.0095
Brugia malayi DOMON domain containing protein 0.0095 0.0391 0.089
Echinococcus granulosus glutamate receptor ionotrophic AMPA 3 0.004 0.0104 0.0102
Leishmania major heat shock protein 83-1 0.0034 0.0073 0.0288
Echinococcus multilocularis isocitrate dehydrogenase 2 (NADP+) 0.0067 0.0242 0.024
Leishmania major 4-coumarate:coa ligase-like protein 0.0049 0.0148 0.0776
Trypanosoma cruzi metacaspase 5, putative 0.0028 0.004 0.0128
Brugia malayi RNA, U transporter 1 0.0252 0.1216 0.2766
Schistosoma mansoni heat shock protein 0.0034 0.0073 0.0095
Entamoeba histolytica fructose-1,6-bisphosphate aldolase, putative 0.0611 0.3094 1
Mycobacterium ulcerans endonuclease IV 0.0076 0.0294 0.1854
Mycobacterium ulcerans aldehyde dehydrogenase 0.0066 0.0239 0.1475
Trypanosoma brucei DNA polymerase kappa, putative 0.0065 0.0236 0.1503
Brugia malayi Copper type II ascorbate-dependent monooxygenase, N-terminal domain containing protein 0.0252 0.1215 0.2762
Loa Loa (eye worm) hypothetical protein 0.0036 0.0082 0.0163
Trichomonas vaginalis DNA helicase recq1, putative 0.0086 0.0342 0.0677
Schistosoma mansoni gcn5proteinral control of amino-acid synthesis 5-like 2 gcnl2 0.0164 0.075 0.0976
Trichomonas vaginalis Clan CD, family C14, metacaspase-like cysteine peptidase 0.0028 0.004 0.0075
Leishmania major isocitrate dehydrogenase [NADP], mitochondrial precursor, putative 0.0067 0.0242 0.1384
Trichomonas vaginalis penicillin-binding protein, putative 0.0039 0.0098 0.0191
Brugia malayi Animal haem peroxidase family protein 0.0051 0.0162 0.0369
Trypanosoma brucei Poly(ADP-ribose) polymerase and DNA-Ligase Zn-finger region/Zinc-finger (CX5CX6HX5H) motif containing protein, putative 0.0037 0.0086 0.0548
Trypanosoma cruzi DNA polymerase kappa, putative 0.0065 0.0236 0.1392
Onchocerca volvulus Huntingtin homolog 0.0132 0.0585 0.1161
Schistosoma mansoni FTZ-F1 nuclear receptor-like protein 0.0022 0.0008 0.0011
Onchocerca volvulus 0.0095 0.0391 0.0775
Echinococcus granulosus nuclear receptor 2DBD gamma 0.0022 0.0008 0.0006
Loa Loa (eye worm) hypothetical protein 0.0141 0.0632 0.1295
Trichomonas vaginalis alpha-glucosidase, putative 0.0038 0.0094 0.0181
Brugia malayi Nuclear hormone receptor family member nhr-40 0.0022 0.0008 0.0019
Trypanosoma brucei hypothetical protein, conserved 0.0225 0.1075 0.6842
Loa Loa (eye worm) hypothetical protein 0.0142 0.0635 0.13
Echinococcus multilocularis thyroid hormone receptor alpha 0.0022 0.0008 0.0006
Entamoeba histolytica hypothetical protein 0.0038 0.0093 0.0293
Brugia malayi DNA-(Apurinic or apyrimidinic site) lyase 0.0076 0.0294 0.0668
Mycobacterium tuberculosis Conserved protein 0.0039 0.0098 0.0486
Echinococcus multilocularis lysosomal alpha glucosidase 0.0173 0.0798 0.0796
Loa Loa (eye worm) nuclear hormone receptor family member nhr-40 0.0022 0.0008 0.0011
Echinococcus multilocularis zinc finger protein 0.0047 0.0137 0.0134
Mycobacterium ulcerans lipase LipD 0.0039 0.0098 0.0486
Brugia malayi Steroid receptor seven-up type 2 0.0022 0.0008 0.0019
Toxoplasma gondii isocitrate dehydrogenase 0.0067 0.0242 0.061
Leishmania major myo-inositol-1(or 4)-monophosphatase 1, putative 0.0039 0.0098 0.0452
Brugia malayi hypothetical protein 0.0157 0.0714 0.1623
Plasmodium vivax ATP-dependent DNA helicase Q1, putative 0.0023 0.0015 0.0178
Schistosoma mansoni microtubule-associated protein tau 0.1486 0.7684 1
Trypanosoma brucei metacaspase MCA2 0.0028 0.004 0.0255
Echinococcus granulosus peregrin 0.0082 0.032 0.0318
Echinococcus multilocularis fetal alzheimer antigen, falz 0.0049 0.0149 0.0146
Onchocerca volvulus 0.0051 0.0158 0.0309
Entamoeba histolytica Ran family GTPase 0.0065 0.0235 0.0753
Schistosoma mansoni scm-relatedprotein containing 4 mbt domains (sfmbt) 0.0051 0.0158 0.0205
Loa Loa (eye worm) hypothetical protein 0.0049 0.0148 0.0299
Brugia malayi calcium-independent alpha-latrotoxin receptor 2, putative 0.0152 0.0689 0.1567
Brugia malayi ImpB/MucB/SamB family protein 0.0036 0.0082 0.0187
Loa Loa (eye worm) inositol-1 0.0039 0.0098 0.0196
Toxoplasma gondii ATP-dependent DNA helicase, RecQ family protein 0.0048 0.0143 0.036
Leishmania major heat shock protein 83-1 0.0034 0.0073 0.0288
Mycobacterium tuberculosis Probable fatty-acid-CoA ligase FadD35 (fatty-acid-CoA synthetase) (fatty-acid-CoA synthase) 0.0034 0.0073 0.0312
Trichomonas vaginalis alpha-glucosidase, putative 0.0038 0.0094 0.0181
Trichomonas vaginalis conserved hypothetical protein 0.0028 0.004 0.0075
Loa Loa (eye worm) nuclear hormone receptor family member nhr-1 0.0022 0.0008 0.0011
Echinococcus multilocularis ecdysone induced protein 78C 0.0022 0.0008 0.0006
Echinococcus multilocularis nuclear receptor 2DBD gamma 0.0022 0.0008 0.0006
Loa Loa (eye worm) animal heme peroxidase 0.0051 0.0162 0.0328
Echinococcus multilocularis JmjC domain containing protein 4 0.0044 0.0121 0.0118
Trypanosoma cruzi DNA polymerase kappa, putative 0.0065 0.0236 0.1392
Trichomonas vaginalis ap endonuclease, putative 0.0039 0.0096 0.0185
Echinococcus granulosus ATP dependent DNA helicase Q1 0.0048 0.0143 0.014
Loa Loa (eye worm) intermediate filament tail domain-containing protein 0.0142 0.0635 0.13
Mycobacterium ulcerans hypothetical protein 0.0049 0.0148 0.0838
Schistosoma mansoni alpha-glucosidase 0.0149 0.0672 0.0874
Brugia malayi ecdysteroid receptor 0.0022 0.0008 0.0019
Mycobacterium ulcerans acyl-CoA synthetase 0.0049 0.0148 0.0838
Schistosoma mansoni phd/f-box containing protein 0.0044 0.0121 0.0157
Trichomonas vaginalis conserved hypothetical protein 0.0028 0.004 0.0075
Loa Loa (eye worm) MH2 domain-containing protein 0.038 0.1886 0.3876
Entamoeba histolytica heat shock protein 90, putative 0.0034 0.0073 0.0229
Schistosoma mansoni jumonji domain containing protein 0.025 0.1206 0.1569
Echinococcus multilocularis cathepsin b 0.0141 0.0632 0.063
Brugia malayi Ligand-binding domain of nuclear hormone receptor family protein 0.0022 0.0008 0.0019
Echinococcus granulosus poly (ADP ribose) polymerase 0.0044 0.0123 0.012
Trypanosoma brucei heat shock protein 90, putative 0.0034 0.0073 0.0466
Brugia malayi Nuclear hormone receptor family member nhr-49 0.0022 0.0008 0.0019
Echinococcus granulosus cadherin EGF LAG seven pass G type receptor 0.0152 0.0689 0.0687
Loa Loa (eye worm) GTP-binding nuclear protein RAN/TC4 0.0065 0.0235 0.0478
Trichomonas vaginalis maltase-glucoamylase, putative 0.0038 0.0094 0.0181
Trichomonas vaginalis DNA polymerase eta, putative 0.0065 0.0236 0.0466
Entamoeba histolytica fructose-1,6-bisphosphate aldolase, putative 0.0611 0.3094 1
Trichomonas vaginalis DNA helicase recq, putative 0.0086 0.0342 0.0677
Trypanosoma cruzi metacaspase, putative 0.0028 0.004 0.0128
Echinococcus granulosus glutamate receptor 2 0.0025 0.0026 0.0024
Trichomonas vaginalis importin beta-1, putative 0.0072 0.027 0.0533
Leishmania major heat shock protein 83-1 0.0034 0.0073 0.0288
Echinococcus granulosus heat shock protein 90 0.0027 0.0036 0.0034
Entamoeba histolytica glycosyl hydrolase, family 31 protein 0.0038 0.0094 0.0294
Loa Loa (eye worm) hypothetical protein 0.0022 0.0008 0.0011
Trypanosoma cruzi 2,4-dihydroxyhept-2-ene-1,7-dioic acid aldolase, putative 0.0026 0.0029 0.0055
Schistosoma mansoni Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) 0.0098 0.0406 0.0528
Brugia malayi heat shock protein 90 0.0034 0.0073 0.0167
Trypanosoma brucei DNA polymerase kappa, putative 0.0032 0.0062 0.0393
Brugia malayi beta-lactamase family protein 0.0039 0.0098 0.0223
Schistosoma mansoni tar DNA-binding protein 0.0067 0.0246 0.032
Schistosoma mansoni hypothetical protein 0.0038 0.0093 0.0121
Schistosoma mansoni hypothetical protein 0.1091 0.5613 0.7304
Schistosoma mansoni retinoic acid receptor RXR 0.0022 0.0008 0.0011
Leishmania major heat shock protein 83-1 0.0034 0.0073 0.0288
Echinococcus granulosus guanine nucleotide binding protein Gs subunit 0.0098 0.0406 0.0404
Schistosoma mansoni cathepsin B-like peptidase (C01 family) 0.0141 0.0632 0.0823
Schistosoma mansoni DNA helicase recq1 0.0048 0.0143 0.0186
Loa Loa (eye worm) hypothetical protein 0.0051 0.0162 0.0328
Echinococcus granulosus lamin 0.0142 0.0635 0.0633
Brugia malayi Nuclear hormone receptor family member nhr-25 0.0022 0.0008 0.0019
Loa Loa (eye worm) hypothetical protein 0.0039 0.0098 0.0196
Echinococcus multilocularis cadherin EGF LAG seven pass G type receptor 0.0152 0.0689 0.0687
Brugia malayi isocitrate dehydrogenase 0.0067 0.0242 0.0551
Leishmania major heat shock protein 83-1 0.0034 0.0073 0.0288
Entamoeba histolytica acetyltransferase, GNAT family 0.0043 0.0117 0.0369
Trypanosoma brucei ISWI complex protein 0.0032 0.0061 0.0387
Mycobacterium tuberculosis NADH-dependent enoyl-[acyl-carrier-protein] reductase InhA (NADH-dependent enoyl-ACP reductase) 0.0185 0.0861 0.5825
Schistosoma mansoni jumonji/arid domain-containing protein 0.022 0.1049 0.1365
Echinococcus multilocularis heat shock protein 90 0.0034 0.0073 0.0071
Schistosoma mansoni hypothetical protein 0.1091 0.5613 0.7304
Brugia malayi Tnks protein 0.0021 0.0003 0.0007
Loa Loa (eye worm) hypothetical protein 0.0051 0.0162 0.0328
Echinococcus granulosus peptidyl glycine alpha amidating monooxygenase 0.0497 0.2498 0.2496
Schistosoma mansoni alkaline phosphatase 0.0172 0.0796 0.1036
Mycobacterium ulcerans DNA polymerase IV 0.0065 0.0236 0.1451
Brugia malayi Importin beta-1 subunit 0.0089 0.0358 0.0814
Echinococcus multilocularis tyrosyl DNA phosphodiesterase 1 0.007 0.0259 0.0257
Mycobacterium ulcerans cytochrome P450 185A4 Cyp185A4 0.0035 0.0076 0.0328
Brugia malayi Tyrosyl-DNA phosphodiesterase family protein 0.007 0.0259 0.059
Brugia malayi Bromodomain containing protein 0.0163 0.0746 0.1696
Loa Loa (eye worm) jmjC domain-containing protein 0.0044 0.0121 0.0243
Loa Loa (eye worm) hypothetical protein 0.0039 0.0098 0.0196
Loa Loa (eye worm) jmjC domain-containing protein 0.0264 0.1276 0.2621
Toxoplasma gondii histone lysine acetyltransferase GCN5-A 0.0052 0.0163 0.0411
Schistosoma mansoni hypothetical protein 0.0328 0.1614 0.21
Toxoplasma gondii GTP-binding nuclear protein ran/tc4 0.0065 0.0235 0.0592
Trypanosoma cruzi importin beta-1 subunit, putative 0.0072 0.027 0.1612
Plasmodium vivax ADP-dependent DNA helicase RecQ, putative 0.0054 0.0178 0.2072
Trichomonas vaginalis D-aminoacylase, putative 0.0039 0.0098 0.0191
Loa Loa (eye worm) hypothetical protein 0.0068 0.0251 0.051
Schistosoma mansoni cathepsin B-like peptidase (C01 family) 0.0141 0.0632 0.0823
Loa Loa (eye worm) GTP-binding regulatory protein Gs alpha-S chain 0.0098 0.0406 0.0829
Trypanosoma brucei DNA polymerase kappa, putative 0.0065 0.0236 0.1503
Trypanosoma cruzi Heat shock protein 83, putative 0.0034 0.0073 0.0342
Echinococcus granulosus beta LACTamase domain containing family member 0.0039 0.0098 0.0096
Schistosoma mansoni inositol monophosphatase 0.0039 0.0098 0.0128
Echinococcus granulosus snurportin 1 0.0948 0.4861 0.486
Echinococcus granulosus neutral alpha glucosidase AB 0.0038 0.0094 0.0091
Brugia malayi MH2 domain containing protein 0.038 0.1886 0.4289
Schistosoma mansoni dopamine-beta-monooxygenase 0.0941 0.4825 0.6278
Echinococcus granulosus alkaline phosphatase intestinal gene 2 0.0172 0.0796 0.0794
Brugia malayi cytoplasmic intermediate filament protein 0.0076 0.029 0.066
Entamoeba histolytica tyrosyl-DNA phosphodiesterase, putative 0.007 0.0259 0.0831
Loa Loa (eye worm) hypothetical protein 0.0066 0.0237 0.0482
Brugia malayi GTP-binding nuclear protein RAN/TC4 0.0065 0.0235 0.0535
Echinococcus granulosus lysine specific demethylase 6a 0.0044 0.0121 0.0118
Loa Loa (eye worm) glycosyl hydrolase family 31 protein 0.0173 0.0798 0.1636
Brugia malayi PHD-finger family protein 0.0026 0.003 0.0067
Loa Loa (eye worm) PHD-finger family protein 0.0043 0.0119 0.0239
Toxoplasma gondii histone lysine methyltransferase SET/SUV39 0.0124 0.0544 0.137
Echinococcus multilocularis guanine nucleotide binding protein G(s) subunit 0.0098 0.0406 0.0404
Trypanosoma cruzi Present in the outer mitochondrial membrane proteome 4 0.0034 0.0072 0.0335
Mycobacterium ulcerans long-chain-fatty-acid-CoA ligase 0.0049 0.0148 0.0838
Echinococcus granulosus histone lysine N methyltransferase NSD3 0.0039 0.0098 0.0096
Schistosoma mansoni protein phosphatase 2C 0.0044 0.0121 0.0157
Leishmania major metacaspase, putative 0.0028 0.004 0.0074
Trypanosoma brucei DNA polymerase kappa, putative 0.0065 0.0236 0.1503
Loa Loa (eye worm) hypothetical protein 0.0066 0.0237 0.0482
Trichomonas vaginalis Importin beta-1 subunit, putative 0.0072 0.027 0.0533
Toxoplasma gondii glycosyl hydrolase, family 31 protein 0.0038 0.0094 0.0236
Schistosoma mansoni caspase-7 (C14 family) 0.0028 0.004 0.0052
Trypanosoma brucei DNA polymerase kappa, putative 0.0065 0.0236 0.1503
Toxoplasma gondii ICE family protease (caspase) p20 domain-containing protein 0.0028 0.004 0.0101
Leishmania major DNA polymerase kappa, putative 0.0043 0.0121 0.0595
Trypanosoma cruzi heat shock protein 85, putative 0.0034 0.0073 0.0342
Trypanosoma cruzi cysteine peptidase C (CPC), putative 0.0049 0.0151 0.0845
Schistosoma mansoni Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) 0.0098 0.0406 0.0528
Leishmania major cysteine peptidase C (CPC),CPC cysteine peptidase, Clan CA, family C1, Cathepsin B-like 0.0049 0.0151 0.0794
Trichomonas vaginalis fructose-bisphosphate aldolase, putative 0.0611 0.3094 0.6164
Loa Loa (eye worm) pigment dispersing factor receptor c 0.048 0.241 0.4955
Echinococcus multilocularis NADP dependent isocitrate dehydrogenase 0.0067 0.0242 0.024
Trypanosoma cruzi cytochrome P450, putative 0.0035 0.0076 0.0357
Echinococcus granulosus alkaline phosphatase 0.0172 0.0796 0.0794
Echinococcus multilocularis FTZ F1 nuclear receptor protein 0.0022 0.0008 0.0006
Echinococcus granulosus histone lysine methyltransferase setb 0.016 0.0731 0.0729
Leishmania major heat shock protein 83-1 0.0034 0.0073 0.0288
Leishmania major heat shock protein 83-1 0.0034 0.0073 0.0288
Trichomonas vaginalis Clan CD, family C14, metacaspase-like cysteine peptidase 0.0028 0.004 0.0075
Brugia malayi ATP-dependent DNA helicase, RecQ family protein 0.0048 0.0143 0.0325
Plasmodium falciparum phd finger protein, putative 0.0063 0.0221 0.2569
Loa Loa (eye worm) hypothetical protein 0.0026 0.003 0.0054
Echinococcus granulosus GTP binding nuclear protein Ran 0.0065 0.0235 0.0233
Mycobacterium ulcerans fusion of enoyl-CoA hydratase, EchA21 and lipase, LipE 0.0039 0.0098 0.0486

Activities

Activity type Activity value Assay description Source Reference
IC50 (functional) > 25 uM Neuronal sodium channel blocking activity by [14C]-guanidinium flux assay ChEMBL. 11229757
IC50 (functional) > 25 uM Neuronal sodium channel blocking activity by [14C]-guanidinium flux assay ChEMBL. 11229757
IC50 (functional) = 81 uM Cardiac sodium channel blocking activity by [14C]-guanidinium flux assay ChEMBL. 11229757
Ki (binding) = 6587 nM In vitro displacement of [3H]-MK-801 from N-methyl-D-aspartate glutamate receptor ChEMBL. 11229757
Ki (binding) = 6587 nM In vitro displacement of [3H]-MK-801 from N-methyl-D-aspartate glutamate receptor ChEMBL. 11229757

Phenotypes

Whole-cell/tissue/organism interactions

We have no records of whole-cell/tissue assays done with this compound What does this mean?

Many chemical entities in TDR Targets come from high-throughput screenings with whole cells or tissue samples, and not all assayed compounds have been tested against a single a single target protein, probably because they get ruled out during screening process. Even if these compounds may have not been of interest in the original screening, they may come as interesting leads for other screening assays. Furthermore, we may be able to propose drug-target associations using chemical similarities and network patterns.

Annotated phenotypes:

We have no manually annotated phenotypes for this drug. What does this mean? / Care to help?
In TDR Targets, information about phenotypes that are caused by drugs, or by genetic manipulation of cells (e.g. gene knockouts or knockdowns) is manually curated from the literature. These descriptions help to describe the potential of the target for drug development. If no information is available for this gene or if the information is incomplete, this may mean that i) the papers containing this information either appeared after the curation effort for this organism was carried out or they were inadvertently missed by curators; or that ii) the curation effort for this organism has not yet started.
 
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External resources for this compound

No external resources registered for this compound

Bibliographic References

1 literature reference was collected for this gene.

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