Detailed information for compound 265066

Basic information

Technical information
  • TDR Targets ID: 265066
  • Name: 2-[2-aminopropanoyl(methyl)amino]acetic acid
  • MW: 160.171 | Formula: C6H12N2O3
  • H donors: 1 H acceptors: 3 LogP: -2.82 Rotable bonds: 4
    Rule of 5 violations (Lipinski): 1
  • SMILES: [O-]C(=O)CN(C(=O)C([NH3+])C)C
  • InChi: 1S/C6H12N2O3/c1-4(7)6(11)8(2)3-5(9)10/h4H,3,7H2,1-2H3,(H,9,10)
  • InChiKey: ZDRWFRSNOABMAL-UHFFFAOYSA-N  


Substructure search Similarity search

Network

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Synonyms

  • 2-[(2-amino-1-oxopropyl)-methylamino]acetic acid
  • 2-[2-azanylpropanoyl(methyl)amino]ethanoic acid
  • 2-[alanyl(methyl)amino]acetic acid
  • 2-(2-aminopropanoyl-methylamino)acetic acid
  • 2-(2-aminopropanoyl-methyl-amino)acetic acid
  • 2-(alanyl-methyl-amino)acetic acid
  • 2-(2-aminopropanoyl-methyl-amino)ethanoic acid

Targets

Known targets for this compound

No curated genes were found associated with this compound

Predicted pathogen targets for this compound

By orthology
No druggable targets predicted by orthology data
By sequence similarity to non orthologous known druggable targets
No druggable targets predicted by sequence similarity
Obtained from network model

Ranking Plot

Putative Targets List

Species Potential target Raw Global Species
Plasmodium vivax unspecified product 0.0243 0.2084 0.5155
Loa Loa (eye worm) fibroinase 0.0442 0.3861 0.3861
Brugia malayi Iron-sulfur cluster assembly accessory protein 0.0048 0.0341 0.0325
Schistosoma mansoni cathepsin C 0.0107 0.0872 0.0862
Plasmodium vivax serine-repeat antigen (SERA), putative 0.0107 0.0872 0.1851
Loa Loa (eye worm) ctsf protein 0.0442 0.3861 0.3861
Echinococcus granulosus nuclear factor of activated T cells 5 0.0119 0.0976 0.0976
Mycobacterium tuberculosis Conserved protein 0.0036 0.0231 0.0999
Plasmodium vivax serine-repeat antigen (SERA) 0.0107 0.0872 0.1851
Brugia malayi MBOAT family protein 0.0031 0.0193 0.0177
Brugia malayi POT family protein 0.0049 0.0353 0.0338
Echinococcus granulosus cathepsin L 0.0107 0.0872 0.0872
Echinococcus granulosus cathepsin L 0.0243 0.2084 0.2084
Trypanosoma brucei DNA polymerase kappa, putative 0.0016 0.0059 0.0059
Entamoeba histolytica cysteine protease, putative 0.0243 0.2084 0.5377
Mycobacterium ulcerans esterase/lipase LipP 0.0036 0.0231 0.7892
Loa Loa (eye worm) papain family cysteine protease containing protein 0.0107 0.0872 0.0872
Echinococcus granulosus lysophospholipid acyltransferase 7 0.0031 0.0193 0.0193
Trypanosoma cruzi cysteine peptidase, putative 0.1114 0.9865 0.9864
Echinococcus multilocularis dnaJ subfamily B 0.0449 0.3926 0.3926
Schistosoma mansoni dishevelled 0.0016 0.0057 0.0047
Plasmodium falciparum serine repeat antigen 2 0.0107 0.0872 0.1851
Trypanosoma cruzi glycerol uptake protein, putative 0.0031 0.0193 0.0177
Entamoeba histolytica cysteine protease, putative 0.0107 0.0872 0.2226
Schistosoma mansoni mixed-lineage leukemia protein mll 0.0067 0.051 0.05
Echinococcus multilocularis lamin 0.0027 0.0152 0.0152
Loa Loa (eye worm) DIX domain-containing protein 0.0016 0.0057 0.0057
Mycobacterium leprae possible inositol monophosphatase SubH (IMPase) (inositol-1-phosphatase) (I-1-Pase ). 0.0035 0.0221 0.9397
Trypanosoma brucei cysteine peptidase C (CPC) 0.0423 0.3695 0.3745
Schistosoma mansoni cpg binding protein 0.0033 0.0211 0.02
Loa Loa (eye worm) nuclear Hormone Receptor family member 0.0017 0.0063 0.0063
Brugia malayi Nuclear hormone receptor family member nhr-31 0.0017 0.0063 0.0048
Loa Loa (eye worm) hypothetical protein 0.0107 0.0872 0.0872
Giardia lamblia Cathepsin B precursor 0.0107 0.0872 0.2148
Treponema pallidum alginate O-acetylation protein (algI) 0.0031 0.0193 0.5
Entamoeba histolytica cysteine proteinase, putative 0.0243 0.2084 0.5377
Trypanosoma cruzi GUP1, putative 0.0031 0.0193 0.0177
Echinococcus multilocularis cathepsin b 0.1129 1 1
Mycobacterium ulcerans extragenic suppressor protein SuhB 0.0039 0.0257 0.9116
Echinococcus multilocularis regulator of G protein signaling 7 0.0016 0.0057 0.0057
Toxoplasma gondii hypothetical protein 0.0031 0.0193 0.0472
Trypanosoma brucei Lanosterol 14-alpha demethylase 0.0017 0.0064 0.0063
Schistosoma mansoni coup transcription factor 0.0017 0.0063 0.0053
Loa Loa (eye worm) cytochrome P450 family protein 0.0025 0.0138 0.0138
Giardia lamblia Cysteine protease 0.0107 0.0872 0.2148
Plasmodium vivax dipeptidyl aminopeptidase 3, putative 0.0107 0.0872 0.1851
Schistosoma mansoni retinoblastoma-binding protein 4 (rbbp4) 0.0023 0.0122 0.0112
Schistosoma mansoni SmCL2-like peptidase (C01 family) 0.0243 0.2084 0.2075
Loa Loa (eye worm) hypothetical protein 0.0107 0.0872 0.0872
Schistosoma mansoni hypothetical protein 0.0019 0.0079 0.0068
Echinococcus multilocularis jun protein 0.0078 0.061 0.061
Brugia malayi cathepsin L precursor 0.0107 0.0872 0.0857
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0243 0.2084 0.5377
Trypanosoma cruzi cysteine protease, putative 0.0243 0.2084 0.2071
Plasmodium falciparum cysteine proteinase falcipain 1 0.0243 0.2084 0.5155
Echinococcus granulosus nuclear receptor 2DBD gamma 0.0017 0.0063 0.0063
Trichomonas vaginalis conserved hypothetical protein 0.0107 0.0872 0.2226
Giardia lamblia Cathepsin B precursor 0.0423 0.3695 1
Giardia lamblia Cathepsin L-like protease 0.0107 0.0872 0.2148
Schistosoma mansoni thyroid hormone receptor 0.0103 0.0835 0.0826
Mycobacterium tuberculosis Cytochrome P450 121 Cyp121 0.0017 0.0064 0.012
Trypanosoma brucei DNA polymerase kappa, putative 0.0021 0.0099 0.0099
Mycobacterium tuberculosis Probable cytochrome P450 137 Cyp137 0.0017 0.0064 0.012
Echinococcus granulosus cathepsin l1 0.0306 0.2649 0.2649
Trypanosoma brucei DNA polymerase kappa, putative 0.0041 0.0276 0.0279
Trichomonas vaginalis Clan CA, family C1, cathepsin L or K-like cysteine peptidase 0.0442 0.3861 1
Loa Loa (eye worm) RasGEF domain-containing protein 0.0012 0.0016 0.0016
Schistosoma mansoni hypothetical protein 0.0308 0.2667 0.2659
Entamoeba histolytica cysteine protease, putative 0.0107 0.0872 0.2226
Schistosoma mansoni cathepsin B-like peptidase (C01 family) 0.1129 1 1
Echinococcus granulosus segment polarity protein dishevelled 0.0016 0.0057 0.0057
Trypanosoma cruzi myo-inositol-1(or 4)-monophosphatase 1, putative 0.0039 0.0257 0.0242
Echinococcus granulosus o acyltransferase membrane bound domain 0.0031 0.0193 0.0193
Mycobacterium tuberculosis Probable cytochrome P450 124 Cyp124 0.0017 0.0064 0.012
Entamoeba histolytica cysteine protease, putative 0.0243 0.2084 0.5377
Trypanosoma cruzi cysteine peptidase, clan CA, family C1, cathepsin L-like, putative 0.0978 0.8653 0.865
Plasmodium falciparum serine repeat antigen 8 0.0107 0.0872 0.1851
Brugia malayi Hhat protein 0.0031 0.0193 0.0177
Trichomonas vaginalis penicillin-binding protein, putative 0.0036 0.0231 0.056
Schistosoma mansoni hypothetical protein 0.0019 0.0079 0.0068
Echinococcus granulosus netrin receptor unc 5 0.0023 0.012 0.012
Mycobacterium ulcerans DNA polymerase IV 0.0041 0.0276 1
Onchocerca volvulus 0.0442 0.3861 0.9064
Mycobacterium tuberculosis Possible cytochrome P450 135B1 Cyp135B1 0.0017 0.0064 0.012
Leishmania major DNA polymerase kappa, putative 0.0021 0.0099 0.0059
Echinococcus multilocularis cathepsin L 0.0107 0.0872 0.0872
Brugia malayi RNA binding protein 0.0063 0.0473 0.0458
Giardia lamblia Cathepsin B-like cysteine proteinase 3 precursor 0.0107 0.0872 0.2148
Loa Loa (eye worm) hypothetical protein 0.1129 1 1
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0442 0.3861 1
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0107 0.0872 0.2226
Loa Loa (eye worm) hypothetical protein 0.0107 0.0872 0.0872
Loa Loa (eye worm) POT family protein 0.0049 0.0353 0.0353
Echinococcus multilocularis lysophospholipid acyltransferase 7 0.0031 0.0193 0.0193
Mycobacterium tuberculosis Possible DNA-damage-inducible protein P DinP (DNA polymerase V) (pol IV 2) (DNA nucleotidyltransferase (DNA-directed)) 0.0021 0.0099 0.0306
Schistosoma mansoni ras GTP exchange factor son of sevenless 0.0012 0.0016 0.0005
Trypanosoma cruzi Lanosterol 14-alpha demethylase 0.0017 0.0064 0.0048
Entamoeba histolytica cysteine protease, putative 0.0107 0.0872 0.2226
Schistosoma mansoni hypothetical protein 0.004 0.0271 0.026
Echinococcus granulosus Nuclear hormone receptor family member nhr 41 0.0017 0.0063 0.0063
Trypanosoma brucei DNA polymerase kappa, putative 0.0041 0.0276 0.0279
Loa Loa (eye worm) hypothetical protein 0.0036 0.0231 0.0231
Brugia malayi Cathepsin L-like precursor 0.0442 0.3861 0.3852
Brugia malayi Nuclear hormone receptor family member nhr-40 0.0017 0.0063 0.0048
Leishmania major cathepsin L-like protease 0.0442 0.3861 0.3889
Loa Loa (eye worm) Papain cysteine protease/cathepsin propeptide inhibitor-containing protein 0.0442 0.3861 0.3861
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0442 0.3861 1
Leishmania major cathepsin L-like protease 0.0442 0.3861 0.3889
Echinococcus granulosus cadherin EGF LAG seven pass G type receptor 0.0019 0.0079 0.0079
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0442 0.3861 1
Schistosoma mansoni Tr4/Tr2 (homologue) 0.0017 0.0063 0.0053
Schistosoma mansoni cytochrome P450 0.0017 0.0064 0.0053
Loa Loa (eye worm) hypothetical protein 0.0239 0.2048 0.2048
Brugia malayi fibroinase precursor 0.0107 0.0872 0.0857
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0442 0.3861 1
Brugia malayi ecdysteroid receptor 0.0017 0.0063 0.0048
Loa Loa (eye worm) RasGEF domain-containing protein 0.0012 0.0016 0.0016
Plasmodium falciparum serine repeat antigen 3 0.0107 0.0872 0.1851
Trichomonas vaginalis transmembrane protein nessy, putative 0.0031 0.0193 0.046
Echinococcus multilocularis Pleckstrin G protein, interacting region 0.0016 0.0057 0.0057
Schistosoma mansoni hypothetical protein 0.0063 0.048 0.0469
Entamoeba histolytica hypothetical protein 0.0031 0.0193 0.046
Loa Loa (eye worm) hypothetical protein 0.0107 0.0872 0.0872
Onchocerca volvulus Cathepsin L homolog 0.0107 0.0872 0.2017
Giardia lamblia Cysteine protease 0.0107 0.0872 0.2148
Trichomonas vaginalis Clan CA, family C1, papain-like cysteine peptidase 0.0442 0.3861 1
Brugia malayi MBOAT family protein 0.0031 0.0193 0.0177
Echinococcus granulosus tar DNA binding protein 0.0063 0.0473 0.0473
Loa Loa (eye worm) beta-lactamase 0.0036 0.0231 0.0231
Schistosoma mansoni lamin 0.0027 0.0152 0.0141
Brugia malayi N-terminal motif family protein 0.0328 0.2847 0.2836
Echinococcus multilocularis rap guanine nucleotide exchange factor 1 0.0012 0.0016 0.0016
Trypanosoma brucei DNA polymerase IV, putative 0.0041 0.0276 0.0279
Leishmania major cathepsin L-like protease 0.1114 0.9865 1
Onchocerca volvulus 0.0486 0.4258 1
Mycobacterium tuberculosis Inositol-1-monophosphatase SuhB 0.0035 0.0221 0.0946
Echinococcus multilocularis Ankyrin 0.0023 0.0122 0.0122
Plasmodium falciparum cysteine proteinase falcipain 2b 0.0442 0.3861 1
Brugia malayi beta-lactamase 0.0036 0.0231 0.0216
Leishmania major glycerol uptake protein, putative 0.0031 0.0193 0.0154
Brugia malayi Cytochrome P450 family protein 0.0053 0.0387 0.0371
Schistosoma mansoni nuclear hormone receptor 0.0017 0.0063 0.0053
Brugia malayi cathepsin F-like cysteine proteinase 0.0107 0.0872 0.0857
Loa Loa (eye worm) hypothetical protein 0.0328 0.2847 0.2847
Brugia malayi Steroid receptor seven-up type 2 0.0017 0.0063 0.0048
Schistosoma mansoni hypothetical protein 0.0308 0.2667 0.2659
Trypanosoma cruzi myo-inositol-1(or 4)-monophosphatase 1, putative 0.0039 0.0257 0.0242
Trichomonas vaginalis Clan CA, family C1, cathepsin B-like cysteine peptidase 0.0107 0.0872 0.2226
Brugia malayi Nuclear hormone receptor family member nhr-3 0.0017 0.0063 0.0048
Trichomonas vaginalis Clan CA, family C1, cathepsin B-like cysteine peptidase 0.0107 0.0872 0.2226
Brugia malayi Papain family cysteine protease containing protein 0.0107 0.0872 0.0857
Mycobacterium tuberculosis Probable cytochrome P450 144 Cyp144 0.0017 0.0064 0.012
Plasmodium falciparum serine repeat antigen 1 0.0107 0.0872 0.1851
Echinococcus granulosus intermediate filament protein 0.0027 0.0152 0.0152
Entamoeba histolytica cysteine protease, putative 0.0243 0.2084 0.5377
Schistosoma mansoni cathepsin F (C01 family) 0.0442 0.3861 0.3855
Echinococcus granulosus Basic leucine zipper bZIP transcription factor 0.0078 0.061 0.061
Plasmodium falciparum serine repeat antigen 7 0.0107 0.0872 0.1851
Schistosoma mansoni cathepsin F (C01 family) 0.0306 0.2649 0.2641
Loa Loa (eye worm) steroid hormone receptor 0.0017 0.0063 0.0063
Schistosoma mansoni cpg binding protein 0.0032 0.0195 0.0184
Brugia malayi latrophilin 2 splice variant baaae 0.004 0.0271 0.0256
Onchocerca volvulus 0.0017 0.0063 0.0112
Loa Loa (eye worm) hypothetical protein 0.0289 0.2497 0.2497
Trichomonas vaginalis Clan CA, family C1, cathepsin B-like cysteine peptidase 0.0107 0.0872 0.2226
Loa Loa (eye worm) hypothetical protein 0.0107 0.0872 0.0872
Mycobacterium tuberculosis Possible cytochrome P450 126 Cyp126 0.0017 0.0064 0.012
Trichomonas vaginalis conserved hypothetical protein 0.0031 0.0193 0.046
Brugia malayi nuclear hormone receptor 0.0017 0.0063 0.0048
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0243 0.2084 0.2111
Entamoeba histolytica hypothetical protein 0.0036 0.0232 0.0562
Brugia malayi Nuclear hormone receptor family member nhr-49 0.0017 0.0063 0.0048
Schistosoma mansoni cathepsin B-like peptidase (C01 family) 0.1129 1 1
Schistosoma mansoni cathepsin B-like peptidase (C01 family) 0.0107 0.0872 0.0862
Schistosoma mansoni hypothetical protein 0.0023 0.012 0.011
Echinococcus granulosus Mitotic checkpoint protein PRCC C terminal 0.0086 0.0685 0.0685
Schistosoma mansoni cathepsin B-like peptidase (C01 family) 0.1129 1 1
Brugia malayi Cytochrome P450 family protein 0.0025 0.0138 0.0122
Giardia lamblia Cathepsin L precursor 0.0107 0.0872 0.2148
Trypanosoma brucei DNA polymerase kappa, putative 0.0031 0.0188 0.0189
Echinococcus multilocularis Protein son of sevenless 0.0012 0.0016 0.0016
Entamoeba histolytica papain family cysteine protease domain containing protein 0.0107 0.0872 0.2226
Leishmania major cathepsin L-like protease 0.1114 0.9865 1
Brugia malayi bZIP transcription factor family protein 0.0078 0.061 0.0596
Loa Loa (eye worm) CXXC zinc finger family protein 0.0032 0.0195 0.0195
Brugia malayi Nuclear hormone receptor family member nhr-19 0.0017 0.0063 0.0048
Brugia malayi Protein kinase domain containing protein 0.0023 0.012 0.0105
Echinococcus granulosus sterol O acyltransferase 1 0.032 0.2776 0.2776
Trypanosoma cruzi glycerol uptake protein, putative 0.0031 0.0193 0.0177
Mycobacterium tuberculosis Cytochrome P450 51 Cyp51 (CYPL1) (P450-L1A1) (sterol 14-alpha demethylase) (lanosterol 14-alpha demethylase) (P450-14DM) 0.0017 0.0064 0.012
Echinococcus granulosus lamin 0.0027 0.0152 0.0152
Brugia malayi Cathepsin L-like precursor 0.0306 0.2649 0.2638
Echinococcus multilocularis FTZ F1 alpha 0.0017 0.0063 0.0063
Schistosoma mansoni retinoic acid receptor RXR 0.0017 0.0063 0.0053
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.1114 0.9865 1
Mycobacterium ulcerans lipase LipD 0.0036 0.0231 0.7892
Echinococcus granulosus ecdysone induced protein 78C 0.0017 0.0063 0.0063
Giardia lamblia Cathepsin L precursor 0.0107 0.0872 0.2148
Loa Loa (eye worm) hypothetical protein 0.0036 0.0231 0.0231
Schistosoma mansoni dishevelled 0.0016 0.0057 0.0047
Echinococcus granulosus hepatocyte nuclear factor 4 alpha 0.0017 0.0063 0.0063
Brugia malayi cathepsin L-like precursor 0.0306 0.2649 0.2638
Echinococcus multilocularis geminin 0.0308 0.2667 0.2667
Entamoeba histolytica hypothetical protein 0.0107 0.0872 0.2226
Loa Loa (eye worm) hypothetical protein 0.0036 0.0231 0.0231
Giardia lamblia Cathepsin B precursor 0.0107 0.0872 0.2148
Schistosoma mansoni SmCL2-like peptidase (C01 family) 0.0243 0.2084 0.2075
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0243 0.2084 0.2111
Echinococcus granulosus o acyltransferase membrane bound domain 0.0031 0.0193 0.0193
Entamoeba histolytica cysteine protease, putative 0.0243 0.2084 0.5377
Schistosoma mansoni o-acyltransferase (membrane bound) domain containing protein 0.0031 0.0193 0.0182
Entamoeba histolytica cysteine protease, putative 0.0243 0.2084 0.5377
Echinococcus multilocularis segment polarity protein dishevelled 0.0016 0.0057 0.0057
Brugia malayi CXXC zinc finger family protein 0.0032 0.0195 0.0179
Echinococcus granulosus inositol monophosphatase 1 0.0039 0.0257 0.0257
Schistosoma mansoni survival motor neuron protein 0.0048 0.0341 0.033
Loa Loa (eye worm) follicle stimulating hormone receptor 0.0219 0.1872 0.1872
Schistosoma mansoni cathepsin S (C01 family) 0.0107 0.0872 0.0862
Brugia malayi beta-lactamase family protein 0.0036 0.0231 0.0216
Trypanosoma brucei DNA polymerase kappa, putative 0.0041 0.0276 0.0279
Loa Loa (eye worm) hypothetical protein 0.0017 0.0063 0.0063
Trypanosoma brucei DNA polymerase kappa, putative 0.0041 0.0276 0.0279
Trichomonas vaginalis porcupine, putative 0.0031 0.0193 0.046
Loa Loa (eye worm) hypothetical protein 0.0306 0.2649 0.2649
Echinococcus multilocularis Basic leucine zipper (bZIP) transcription factor 0.0078 0.061 0.061
Onchocerca volvulus 0.0061 0.0461 0.1048
Schistosoma mansoni inositol monophosphatase 0.0039 0.0257 0.0247
Echinococcus granulosus Membrane bound O acyl transferase MBOAT 0.0031 0.0193 0.0193
Trypanosoma cruzi cytochrome P450, putative 0.0025 0.0138 0.0122
Echinococcus multilocularis Protein lozenge 0.0061 0.0458 0.0458
Loa Loa (eye worm) hypothetical protein 0.0442 0.3861 0.3861
Loa Loa (eye worm) hypothetical protein 0.0017 0.0063 0.0063
Brugia malayi Intermediate filament tail domain containing protein 0.0027 0.0152 0.0136
Plasmodium falciparum serine repeat antigen 9 0.0107 0.0872 0.1851
Trichomonas vaginalis Clan CA, family C1, cathepsin L, S or H-like cysteine peptidase 0.0107 0.0872 0.2226
Schistosoma mansoni sterol O-acyltransferase 1 0.032 0.2776 0.2769
Brugia malayi hypothetical protein 0.0036 0.0232 0.0217
Echinococcus granulosus cathepsin l cysteine peptidase 0.0442 0.3861 0.3861
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.1114 0.9865 1
Echinococcus multilocularis cathepsin L cysteine protease 0.0442 0.3861 0.3861
Echinococcus granulosus GPCR family 2 0.0019 0.0079 0.0079
Echinococcus granulosus lamin dm0 0.0027 0.0152 0.0152
Trichomonas vaginalis Clan CA, family C1, papain-like cysteine peptidase 0.0442 0.3861 1
Echinococcus granulosus nuclear receptor 2DBD gamma 0.0017 0.0063 0.0063
Loa Loa (eye worm) hypothetical protein 0.0012 0.0016 0.0016
Schistosoma mansoni tar DNA-binding protein 0.0063 0.0473 0.0463
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.1114 0.9865 1
Giardia lamblia Cathepsin L precursor 0.0107 0.0872 0.2148
Trichomonas vaginalis Clan CA, family C1, cathepsin B-like cysteine peptidase 0.0107 0.0872 0.2226
Echinococcus granulosus o acyltransferase membrane bound domain 0.0031 0.0193 0.0193
Schistosoma mansoni ankyrin 23/unc44 0.0023 0.012 0.011
Schistosoma mansoni transcription factor LCR-F1 0.0036 0.0232 0.0221
Brugia malayi RNA recognition motif domain containing protein 0.0063 0.0473 0.0458
Echinococcus multilocularis thyroid hormone receptor alpha 0.0103 0.0835 0.0835
Entamoeba histolytica hypothetical protein 0.0036 0.0232 0.0562
Onchocerca volvulus Bile acid receptor homolog 0.0017 0.0063 0.0112
Plasmodium vivax vivapain-1 0.0243 0.2084 0.5155
Echinococcus granulosus ras GTP exchange factor 0.0012 0.0016 0.0016
Onchocerca volvulus 0.0027 0.0152 0.0321
Echinococcus granulosus jun protein 0.0078 0.061 0.061
Echinococcus multilocularis o acyltransferase (membrane bound) domain 0.0031 0.0193 0.0193
Loa Loa (eye worm) hhat protein 0.0031 0.0193 0.0193
Echinococcus granulosus Ankyrin 0.0023 0.0122 0.0122
Loa Loa (eye worm) hypothetical protein 0.0486 0.4258 0.4258
Mycobacterium tuberculosis Possible conserved lipoprotein LpqK 0.0036 0.0231 0.0999
Echinococcus multilocularis cytoplasmic intermediate filament protein 0.0013 0.0028 0.0028
Brugia malayi calcium-independent alpha-latrotoxin receptor 2, putative 0.0019 0.0079 0.0063
Loa Loa (eye worm) nuclear hormone receptor family member nhr-14 0.0017 0.0063 0.0063
Loa Loa (eye worm) nuclear hormone receptor family member nhr-31 0.0017 0.0063 0.0063
Loa Loa (eye worm) papain family cysteine protease containing protein 0.0107 0.0872 0.0872
Schistosoma mansoni regulator of G protein signaling 0.0016 0.0057 0.0047
Brugia malayi cytochrome P450 0.0017 0.0064 0.0048
Giardia lamblia Dipeptidyl-peptidase I precursor 0.0107 0.0872 0.2148
Schistosoma mansoni cathepsin B (C01 family) 0.0107 0.0872 0.0862
Schistosoma mansoni DNA polymerase eta 0.0014 0.0041 0.003
Loa Loa (eye worm) hypothetical protein 0.0136 0.1125 0.1125
Echinococcus multilocularis FTZ F1 nuclear receptor protein 0.0017 0.0063 0.0063
Brugia malayi Cytochrome P450 family protein 0.0017 0.0064 0.0048
Wolbachia endosymbiont of Brugia malayi fructose-1,6-bisphosphatase 0.0039 0.0257 0.5
Loa Loa (eye worm) cytochrome P450 family protein 0.0053 0.0387 0.0387
Mycobacterium ulcerans fusion of enoyl-CoA hydratase, EchA21 and lipase, LipE 0.0036 0.0231 0.7892
Schistosoma mansoni cathepsin B-like peptidase (C01 family) 0.0107 0.0872 0.0862
Mycobacterium tuberculosis Probable cytochrome P450 123 Cyp123 0.0017 0.0064 0.012
Brugia malayi Nuclear hormone receptor family member nhr-25 0.0017 0.0063 0.0048
Brugia malayi Papain family cysteine protease containing protein 0.0442 0.3861 0.3852
Loa Loa (eye worm) hypothetical protein 0.0012 0.0016 0.0016
Loa Loa (eye worm) hypothetical protein 0.0012 0.0024 0.0024
Toxoplasma gondii acyl-CoA:diacylglycerol acyltransferase 1-related enzyme 0.0031 0.0193 0.0472
Echinococcus granulosus FTZ F1 nuclear receptor protein 0.0017 0.0063 0.0063
Brugia malayi Cathepsin L-like precursor 0.0442 0.3861 0.3852
Plasmodium falciparum dipeptidyl aminopeptidase 1 0.0107 0.0872 0.1851
Loa Loa (eye worm) cytoplasmic intermediate filament protein 0.0014 0.0041 0.0041
Echinococcus multilocularis COUP TF:Svp nuclear hormone receptor 0.0017 0.0063 0.0063
Plasmodium vivax serine-repeat antigen 4 (SERA), putative 0.0107 0.0872 0.1851
Leishmania major myo-inositol-1(or 4)-monophosphatase 1, putative 0.0039 0.0257 0.022
Toxoplasma gondii preprocathepsin c precursor, putative 0.0107 0.0872 0.2236
Mycobacterium tuberculosis Probable esterase LipL 0.0036 0.0231 0.0999
Echinococcus granulosus beta LACTamase domain containing family member 0.0036 0.0231 0.0231
Echinococcus multilocularis nuclear receptor 2DBD gamma 0.0017 0.0063 0.0063
Trypanosoma brucei DNA polymerase kappa, putative 0.0016 0.0059 0.0059
Brugia malayi Calcitonin receptor-like protein seb-1 0.0059 0.0437 0.0422
Echinococcus multilocularis cathepsin l cysteine peptidase 0.0442 0.3861 0.3861
Schistosoma mansoni lamin 0.0027 0.0152 0.0141
Echinococcus multilocularis beta LACTamase domain containing family member 0.0036 0.0231 0.0231
Giardia lamblia Cathepsin L precursor 0.0107 0.0872 0.2148
Loa Loa (eye worm) hypothetical protein 0.0014 0.0041 0.0041
Echinococcus multilocularis Membrane bound O acyl transferase, MBOAT 0.0031 0.0193 0.0193
Mycobacterium tuberculosis Probable esterase/lipase LipP 0.0036 0.0231 0.0999
Entamoeba histolytica hypothetical protein 0.0036 0.0232 0.0562
Echinococcus multilocularis tar DNA binding protein 0.0063 0.0473 0.0473
Toxoplasma gondii histone lysine methyltransferase SET1 0.006 0.0447 0.1132
Mycobacterium ulcerans cytochrome P450 185A4 Cyp185A4 0.0025 0.0138 0.3491
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0107 0.0872 0.2226
Echinococcus multilocularis netrin receptor unc 5 0.0023 0.012 0.012
Echinococcus granulosus FTZ F1 alpha 0.0017 0.0063 0.0063
Leishmania major hypothetical protein, conserved 0.0031 0.0193 0.0154
Trypanosoma brucei DNA polymerase IV, putative 0.0034 0.0218 0.022
Entamoeba histolytica cysteine protease, putative 0.0107 0.0872 0.2226
Schistosoma mansoni rab geranylgeranyl transferase alpha subunit 0.0014 0.0041 0.003
Schistosoma mansoni thyroid hormone receptor 0.0103 0.0835 0.0826
Trypanosoma cruzi cytochrome P450, putative 0.0025 0.0138 0.0122
Loa Loa (eye worm) cytochrome P450 family protein 0.0025 0.0138 0.0138
Loa Loa (eye worm) hypothetical protein 0.004 0.0271 0.0271
Loa Loa (eye worm) intermediate filament tail domain-containing protein 0.0027 0.0152 0.0152
Schistosoma mansoni tar DNA-binding protein 0.0063 0.0473 0.0463
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0107 0.0872 0.2226
Trichomonas vaginalis Clan CA, family C1, cathepsin F-like cysteine peptidase 0.0107 0.0872 0.2226
Leishmania major cytochrome p450-like protein 0.0025 0.0138 0.0099
Loa Loa (eye worm) hypothetical protein 0.0016 0.0057 0.0057
Schistosoma mansoni dipeptidyl-peptidase I (C01 family) 0.0107 0.0872 0.0862
Echinococcus granulosus diacylglycerol O acyltransferase 1 0.0031 0.0193 0.0193
Entamoeba histolytica hypothetical protein 0.0036 0.0232 0.0562
Brugia malayi Nuclear hormone receptor family member nhr-1 0.0017 0.0063 0.0048
Echinococcus granulosus regulator of G protein signaling 7 0.0016 0.0057 0.0057
Brugia malayi steroid hormone receptor 0.0017 0.0063 0.0048
Schistosoma mansoni SmCL2-like peptidase (C01 family) 0.0243 0.2084 0.2075
Giardia lamblia Hypothetical protein 0.0107 0.0872 0.2148
Brugia malayi Nuclear hormone receptor family member nhr-25 0.0017 0.0063 0.0048
Schistosoma mansoni tar DNA-binding protein 0.0063 0.0473 0.0463
Echinococcus granulosus COUP TF:Svp nuclear hormone receptor 0.0017 0.0063 0.0063
Schistosoma mansoni leukocyte receptor cluster (lrc) member 4 protein 0.0031 0.0193 0.0182
Loa Loa (eye worm) hypothetical protein 0.0017 0.0063 0.0063
Echinococcus multilocularis ankyrin repeat and death domain containing protein 0.0023 0.012 0.012
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.1114 0.9865 1
Entamoeba histolytica membrane-bound O-acyltransferase (MBOAT ) family protein 0.0031 0.0193 0.046
Giardia lamblia Cathepsin B precursor 0.0107 0.0872 0.2148
Entamoeba histolytica cysteine proteinase, putative 0.0243 0.2084 0.5377
Echinococcus granulosus ankyrin repeat and death domain containing protein 0.0023 0.012 0.012
Trichomonas vaginalis conserved hypothetical protein 0.0031 0.0193 0.046
Brugia malayi Corticotropin releasing factor receptor 2 precursor, putative 0.0239 0.2048 0.2036
Echinococcus granulosus son of sevenless 1 0.0012 0.0016 0.0016
Trypanosoma brucei cytochrome P450, putative 0.0025 0.0138 0.0139
Mycobacterium tuberculosis Possible cytochrome P450 135A1 Cyp135A1 0.0017 0.0064 0.012
Brugia malayi hypothetical protein 0.0235 0.201 0.1998
Trypanosoma cruzi cysteine peptidase C (CPC), putative 0.1129 1 1
Toxoplasma gondii ABC1 family protein 0.0036 0.0231 0.0572
Schistosoma mansoni ras GTP exchange factor son of sevenless 0.0012 0.0016 0.0005
Loa Loa (eye worm) ImpB/MucB/SamB family protein 0.0014 0.0041 0.0041
Mycobacterium leprae Probable lipase LipE 0.0036 0.0231 1
Schistosoma mansoni photoreceptor-specific nuclear receptor related 0.0017 0.0063 0.0053
Giardia lamblia Dipeptidyl-peptidase I precursor 0.0107 0.0872 0.2148
Schistosoma mansoni intermediate filament proteins 0.0027 0.0152 0.0141
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.1114 0.9865 1
Leishmania major cathepsin L-like protease 0.0442 0.3861 0.3889
Plasmodium vivax vivapain-2 0.0442 0.3861 1
Echinococcus multilocularis hepatocyte nuclear factor 4 alpha 0.0017 0.0063 0.0063
Echinococcus multilocularis cysteine protease 0.0442 0.3861 0.3861
Echinococcus granulosus dna polymerase kappa 0.0041 0.0276 0.0276
Schistosoma mansoni ras GTP exchange factor 0.0012 0.0016 0.0005
Mycobacterium tuberculosis Probable cytochrome P450 143 Cyp143 0.0017 0.0064 0.012
Schistosoma mansoni tar DNA-binding protein 0.0063 0.0473 0.0463
Mycobacterium tuberculosis Probable cytochrome P450 132 Cyp132 0.0017 0.0064 0.012
Trichomonas vaginalis esterase, putative 0.0036 0.0231 0.056
Echinococcus multilocularis dna polymerase eta 0.0014 0.0041 0.0041
Echinococcus granulosus survival motor neuron protein 1 0.0235 0.201 0.201
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0107 0.0872 0.2226
Brugia malayi Cathepsin L-like cysteine proteinase 0.0306 0.2649 0.2638
Schistosoma mansoni hypothetical protein 0.0019 0.0079 0.0068
Schistosoma mansoni cathepsin B-like peptidase (C01 family) 0.0107 0.0872 0.0862
Entamoeba histolytica membrane-bound O-acyltransferase (MBOAT ) family protein 0.0031 0.0193 0.046
Schistosoma mansoni hypothetical protein 0.0019 0.0079 0.0068
Toxoplasma gondii cathepsin CPL 0.0442 0.3861 1
Schistosoma mansoni RAR-like nuclear receptor 0.0017 0.0063 0.0053
Onchocerca volvulus 0.0032 0.0195 0.0421
Brugia malayi Nuclear hormone receptor family member nhr-14 0.0017 0.0063 0.0048
Mycobacterium ulcerans hypothetical protein 0.0036 0.0231 0.7892
Loa Loa (eye worm) MBOAT family protein 0.0031 0.0193 0.0193
Toxoplasma gondii cathepsin CPC2 0.0107 0.0872 0.2236
Brugia malayi Cytochrome P450 family protein 0.0025 0.0138 0.0122
Echinococcus granulosus death domain containing protein 0.0023 0.012 0.012
Loa Loa (eye worm) nuclear hormone receptor family member nhr-49 0.0017 0.0063 0.0063
Entamoeba histolytica cysteine protease, putative 0.0243 0.2084 0.5377
Loa Loa (eye worm) hypothetical protein 0.0016 0.0057 0.0057
Loa Loa (eye worm) TAR-binding protein 0.0063 0.0473 0.0473
Schistosoma mansoni o-acyltransferase (membrane bound) domain containing protein 0.0031 0.0193 0.0182
Leishmania major glycerol uptake protein, putative 0.0031 0.0193 0.0154
Loa Loa (eye worm) hypothetical protein 0.0031 0.0188 0.0188
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0442 0.3861 1
Entamoeba histolytica papain family cysteine protease domain containing protein 0.0107 0.0872 0.2226
Entamoeba histolytica cysteine protease, putative 0.0442 0.3861 1
Plasmodium vivax serine-repeat antigen (SERA) 0.0107 0.0872 0.1851
Trypanosoma brucei unspecified product 0.0034 0.0218 0.022
Entamoeba histolytica deoxycytidyl transferase, putative 0.0014 0.0041 0.0065
Echinococcus multilocularis terminal deoxycytidyl transferase rev1 0.0014 0.0041 0.0041
Trypanosoma cruzi cysteine proteinase, putative 0.0243 0.2084 0.2071
Entamoeba histolytica cysteine protease, putative 0.0243 0.2084 0.5377
Mycobacterium tuberculosis Probable cytochrome P450 138 Cyp138 0.0017 0.0064 0.012
Leishmania major cysteine peptidase C (CPC),CPC cysteine peptidase, Clan CA, family C1, Cathepsin B-like 0.0423 0.3695 0.372
Trichomonas vaginalis Clan CA, family C1, cathepsin L or H-like cysteine peptidase 0.0107 0.0872 0.2226
Leishmania major cytochrome p450-like protein 0.0017 0.0064 0.0023
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0442 0.3861 1
Plasmodium falciparum dipeptidyl aminopeptidase 2 0.0107 0.0872 0.1851
Brugia malayi Ligand-binding domain of nuclear hormone receptor family protein 0.0017 0.0063 0.0048
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0107 0.0872 0.2226
Brugia malayi Domain found in Dishevelled, Egl-10, and Pleckstrin family protein 0.0016 0.0057 0.0042
Trichomonas vaginalis Clan CA, family C1, papain-like cysteine peptidase 0.0107 0.0872 0.2226
Entamoeba histolytica cysteine proteinase, putative 0.0306 0.2649 0.6848
Leishmania major cytochrome p450-like protein 0.0017 0.0064 0.0023
Trypanosoma brucei glycerol uptake protein, putative 0.0031 0.0193 0.0194
Mycobacterium ulcerans beta-lactamase 0.0036 0.0231 0.7892
Brugia malayi nuclear receptor NHR-88 0.0017 0.0063 0.0048
Brugia malayi Nuclear hormone receptor family member nhr-41 0.0017 0.0063 0.0048
Trichomonas vaginalis DNA polymerase IV / kappa, putative 0.0041 0.0276 0.0677
Onchocerca volvulus 0.0442 0.3861 0.9064
Loa Loa (eye worm) hypothetical protein 0.0023 0.0122 0.0122
Loa Loa (eye worm) G protein signaling regulator EGL-10 0.0016 0.0057 0.0057
Leishmania major cysteine peptidase A (CPA) 0.0442 0.3861 0.3889
Echinococcus multilocularis segment polarity protein dishevelled 0.0016 0.0057 0.0057
Loa Loa (eye worm) hypothetical protein 0.0031 0.0193 0.0193
Loa Loa (eye worm) hypothetical protein 0.0012 0.0024 0.0024
Entamoeba histolytica cysteine proteinase, putative 0.0442 0.3861 1
Echinococcus multilocularis 0.0017 0.0064 0.0064
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.1114 0.9865 1
Echinococcus multilocularis nuclear factor of activated T cells 5 0.0119 0.0976 0.0976
Echinococcus multilocularis cathepsin L cysteine protease 0.0442 0.3861 0.3861
Giardia lamblia Cysteine protease 0.0107 0.0872 0.2148
Schistosoma mansoni hypothetical protein 0.0449 0.3926 0.3919
Brugia malayi Inositol-1 0.0039 0.0257 0.0242
Mycobacterium tuberculosis Probable conserved lipoprotein 0.0036 0.0231 0.0999
Echinococcus granulosus cathepsin b 0.1129 1 1
Brugia malayi diacylglycerol acyltransferase 0.0031 0.0193 0.0177
Echinococcus granulosus cathepsin L cysteine protease 0.0243 0.2084 0.2084
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0442 0.3861 1
Trichomonas vaginalis Clan CA, family C1, papain-like cysteine peptidase 0.0107 0.0872 0.2226
Onchocerca volvulus Cathepsin F homolog 0.0442 0.3861 0.9064
Trichomonas vaginalis Clan CA, family C1, papain-like cysteine peptidase 0.0442 0.3861 1
Mycobacterium leprae conserved hypothetical protein 0.0036 0.0231 1
Onchocerca volvulus Cathepsin L homolog 0.0442 0.3861 0.9064
Trichomonas vaginalis Clan CA, family C1, papain-like cysteine peptidase 0.0442 0.3861 1
Brugia malayi cathepsin L-like cysteine proteinase, identical 0.0136 0.1125 0.1111
Loa Loa (eye worm) MBOAT family protein 0.0031 0.0193 0.0193
Plasmodium vivax vivapain-3 0.0243 0.2084 0.5155
Brugia malayi ImpB/MucB/SamB family protein 0.0014 0.0041 0.0025
Trypanosoma cruzi glycerol uptake protein, putative 0.0031 0.0193 0.0177
Trypanosoma cruzi DNA polymerase kappa, putative 0.0041 0.0276 0.0261
Trichomonas vaginalis Clan CA, family C1, papain-like cysteine peptidase 0.0442 0.3861 1
Loa Loa (eye worm) hypothetical protein 0.032 0.2776 0.2776
Brugia malayi Domain found in Dishevelled, Egl-10, and Pleckstrin family protein 0.0016 0.0057 0.0042
Trypanosoma brucei DNA polymerase kappa, putative 0.0031 0.0188 0.0189
Leishmania major cathepsin L-like protease 0.1114 0.9865 1
Loa Loa (eye worm) papain family cysteine protease containing protein 0.0136 0.1125 0.1125
Onchocerca volvulus 0.0306 0.2649 0.6207
Echinococcus multilocularis cysteine protease 0.0442 0.3861 0.3861
Plasmodium falciparum dipeptidyl aminopeptidase 3 0.0107 0.0872 0.1851
Toxoplasma gondii cathepsin CPC1 0.0107 0.0872 0.2236
Brugia malayi Cathepsin L-like precursor 0.0442 0.3861 0.3852
Trypanosoma brucei glycerol uptake protein, putative 0.0031 0.0193 0.0194
Onchocerca volvulus 0.0048 0.0341 0.0766
Echinococcus multilocularis o acyltransferase (membrane bound) domain 0.0031 0.0193 0.0193
Trypanosoma cruzi major cysteine proteinase, putative 0.0107 0.0872 0.0857
Schistosoma mansoni zinc finger protein 0.0031 0.0193 0.0182
Echinococcus granulosus cathepsin b 0.1129 1 1
Loa Loa (eye worm) MBOAT family protein 0.0031 0.0193 0.0193
Schistosoma mansoni fyve finger-containing phosphoinositide kinase fyv1 0.0016 0.0057 0.0047
Giardia lamblia Cathepsin L precursor 0.0107 0.0872 0.2148
Trypanosoma cruzi cruzipain precursor, putative 0.1114 0.9865 0.9864
Loa Loa (eye worm) hhat protein 0.0031 0.0193 0.0193
Plasmodium falciparum serine repeat antigen 5 0.0107 0.0872 0.1851
Brugia malayi Uncoordinated protein 44 0.0023 0.012 0.0105
Entamoeba histolytica cysteine protease, putative 0.0243 0.2084 0.5377
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0442 0.3861 1
Trypanosoma brucei DNA polymerase kappa, putative 0.0016 0.0059 0.0059
Brugia malayi Death domain containing protein 0.0023 0.012 0.0105
Toxoplasma gondii hypothetical protein 0.0016 0.0057 0.012
Brugia malayi polk-prov protein 0.0031 0.0188 0.0172
Loa Loa (eye worm) hypothetical protein 0.0017 0.0063 0.0063
Trypanosoma cruzi GUP1, putative 0.0031 0.0193 0.0177
Entamoeba histolytica cysteine protease, putative 0.0243 0.2084 0.5377
Loa Loa (eye worm) cytochrome P450 0.0017 0.0064 0.0064
Echinococcus multilocularis cathepsin l cysteine peptidase 0.0442 0.3861 0.3861
Loa Loa (eye worm) hypothetical protein 0.0076 0.0591 0.0591
Echinococcus granulosus membrane bound acyltransferase:hhat 0.0031 0.0193 0.0193
Brugia malayi intermediate filament protein 0.0027 0.0152 0.0136
Schistosoma mansoni subfamily C1A unassigned peptidase (C01 family) 0.0107 0.0872 0.0862
Schistosoma mansoni cathepsin B-like peptidase (C01 family) 0.0107 0.0872 0.0862
Loa Loa (eye worm) hypothetical protein 0.0027 0.0152 0.0152
Trichomonas vaginalis Clan CA, family C1, papain-like cysteine peptidase 0.0442 0.3861 1
Trichomonas vaginalis Clan CA, family C1, papain-like cysteine peptidase 0.0442 0.3861 1
Schistosoma mansoni family S12 unassigned peptidase (S12 family) 0.0036 0.0231 0.0221
Mycobacterium tuberculosis Conserved protein 0.0036 0.0231 0.0999
Onchocerca volvulus 0.0036 0.0231 0.0508
Trichomonas vaginalis conserved hypothetical protein 0.0107 0.0872 0.2226
Echinococcus multilocularis nuclear receptor 2DBD gamma 0.0017 0.0063 0.0063
Schistosoma mansoni nuclear receptor 2DBD-gamma 0.0017 0.0063 0.0053
Loa Loa (eye worm) hypothetical protein 0.0306 0.2649 0.2649
Entamoeba histolytica cysteine protease, putative 0.0107 0.0872 0.2226
Entamoeba histolytica cysteine protease, putative 0.0243 0.2084 0.5377
Trichomonas vaginalis D-aminoacylase, putative 0.0036 0.0231 0.056
Echinococcus granulosus terminal deoxycytidyl transferase rev1 0.0014 0.0041 0.0041
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.1114 0.9865 1
Schistosoma mansoni cathepsin s 0.0136 0.1125 0.1115
Plasmodium falciparum cysteine proteinase falcipain 3 0.0442 0.3861 1
Schistosoma mansoni terminal deoxycytidyl transferase 0.0014 0.0041 0.003
Onchocerca volvulus 0.0442 0.3861 0.9064
Echinococcus multilocularis cathepsin L 0.0243 0.2084 0.2084
Echinococcus multilocularis diacylglycerol O acyltransferase 1 0.0031 0.0193 0.0193
Mycobacterium tuberculosis Probable cytochrome P450 136 Cyp136 0.0017 0.0064 0.012
Onchocerca volvulus 0.0031 0.0193 0.0417
Echinococcus granulosus cytochrome P450 2K1 0.0017 0.0064 0.0064
Onchocerca volvulus Cathepsin L homolog 0.0442 0.3861 0.9064
Schistosoma mansoni steroid hormone receptor ad4bp 0.0017 0.0063 0.0053
Brugia malayi Cathepsin L-like precursor 0.0136 0.1125 0.1111
Plasmodium vivax serine-repeat antigen (SERA), putative 0.0107 0.0872 0.1851
Loa Loa (eye worm) hypothetical protein 0.0017 0.0063 0.0063
Brugia malayi Ligand-binding domain of nuclear hormone receptor family protein 0.0017 0.0063 0.0048
Brugia malayi Immunoglobulin I-set domain containing protein 0.0023 0.012 0.0105
Brugia malayi Cathepsin L-like precursor 0.0442 0.3861 0.3852
Trypanosoma cruzi cysteine peptidase, putative 0.0442 0.3861 0.3852
Schistosoma mansoni membrane-bound acyltransferase/hhat 0.0031 0.0193 0.0182
Loa Loa (eye worm) hypothetical protein 0.0136 0.1125 0.1125
Echinococcus granulosus segment polarity protein dishevelled 0.0016 0.0057 0.0057
Schistosoma mansoni cathepsin F (C01 family) 0.0442 0.3861 0.3855
Trypanosoma cruzi major cysteine proteinase, putative 0.0779 0.6875 0.687
Entamoeba histolytica cysteine proteinase 2 0.0243 0.2084 0.5377
Plasmodium vivax dipeptidyl aminopeptidase 2, putative 0.0107 0.0872 0.1851
Loa Loa (eye worm) beta-LACTamase domain containing family member 0.0036 0.0231 0.0231
Brugia malayi Papain family cysteine protease containing protein 0.0107 0.0872 0.0857
Schistosoma mansoni hypothetical protein 0.0031 0.0193 0.0182
Mycobacterium tuberculosis Probable cytochrome P450 monooxygenase 142 Cyp142 0.0017 0.0064 0.012
Entamoeba histolytica cysteine proteinase, putative 0.0442 0.3861 1
Giardia lamblia Dipeptidyl-peptidase I precursor 0.0107 0.0872 0.2148
Onchocerca volvulus 0.0107 0.0872 0.2017
Brugia malayi Cathepsin L-like precursor 0.0442 0.3861 0.3852
Loa Loa (eye worm) RNA binding protein 0.0063 0.0473 0.0473
Brugia malayi regulator of G-protein signaling egl-10 0.0016 0.0057 0.0042
Brugia malayi cahepsin L-like non-peptiedase homolog 0.0107 0.0872 0.0857
Brugia malayi hypothetical protein 0.0061 0.0461 0.0446
Schistosoma mansoni hypothetical protein 0.0036 0.0232 0.0221
Echinococcus multilocularis lamin dm0 0.0027 0.0152 0.0152
Loa Loa (eye worm) hypothetical protein 0.0107 0.0872 0.0872
Trichomonas vaginalis Clan CA, family C1, cathepsin B-like cysteine peptidase 0.0423 0.3695 0.9567
Echinococcus granulosus Protein son of sevenless 0.0012 0.0016 0.0016
Trichomonas vaginalis conserved hypothetical protein 0.0031 0.0193 0.046
Trichomonas vaginalis Clan CA, family C1, cathepsin L or K-like cysteine peptidase 0.0442 0.3861 1
Brugia malayi photoreceptor-specific nuclear receptor 0.0017 0.0063 0.0048
Onchocerca volvulus 0.0027 0.0152 0.0321
Trypanosoma cruzi hypothetical protein, conserved 0.0036 0.0231 0.0216
Loa Loa (eye worm) papain family cysteine protease containing protein 0.0442 0.3861 0.3861
Loa Loa (eye worm) cathepsin B 0.0423 0.3695 0.3695
Brugia malayi Cathepsin L-like precursor 0.0442 0.3861 0.3852
Trypanosoma cruzi cytochrome p450-like protein, putative 0.0017 0.0064 0.0048
Echinococcus granulosus diuretic hormone 44 receptor GPRdih2 0.0199 0.169 0.169
Trypanosoma cruzi DNA polymerase kappa, putative 0.0041 0.0276 0.0261
Loa Loa (eye worm) membrane bound O-acyltransferase domain containing 1 0.0031 0.0193 0.0193
Plasmodium vivax serine-repeat antigen 3 (SERA) 0.0107 0.0872 0.1851
Loa Loa (eye worm) hypothetical protein 0.0031 0.0193 0.0193
Entamoeba histolytica cysteine proteinase, putative 0.0243 0.2084 0.5377
Loa Loa (eye worm) immunoglobulin I-set domain-containing protein 0.0023 0.012 0.012
Leishmania major hypothetical protein, conserved 0.0036 0.0231 0.0194
Schistosoma mansoni tar DNA-binding protein 0.0063 0.0473 0.0463
Echinococcus multilocularis rap guanine nucleotide exchange factor 6 0.0012 0.0016 0.0016
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0243 0.2084 0.5377
Loa Loa (eye worm) hypothetical protein 0.0017 0.0063 0.0063
Echinococcus multilocularis Mitotic checkpoint protein PRCC, C terminal 0.0086 0.0685 0.0685
Echinococcus multilocularis protein cysteine N palmitoyltransferase 0.0031 0.0193 0.0193
Loa Loa (eye worm) RasGEF domain-containing protein 0.0012 0.0016 0.0016
Echinococcus multilocularis membrane bound acyltransferase:hhat 0.0031 0.0193 0.0193
Onchocerca volvulus 0.0036 0.0231 0.0508
Giardia lamblia Cathepsin L-like protease 0.0107 0.0872 0.2148
Toxoplasma gondii inositol(myo)-1(or 4)-monophosphatase 2, putative 0.0039 0.0257 0.064
Echinococcus multilocularis musashi 0.0027 0.0152 0.0152
Schistosoma mansoni dep domain containing protein 0.0016 0.0057 0.0047
Echinococcus granulosus geminin 0.0308 0.2667 0.2667
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0306 0.2649 0.6848
Trypanosoma cruzi DNA polymerase kappa, putative 0.0041 0.0276 0.0261
Echinococcus multilocularis cpg binding protein 0.0033 0.0211 0.0211
Echinococcus granulosus dna polymerase eta 0.0014 0.0041 0.0041
Entamoeba histolytica cysteine proteinase 1, putative 0.0243 0.2084 0.5377
Trichomonas vaginalis Clan CA, family C1, papain-like cysteine peptidase 0.0107 0.0872 0.2226
Loa Loa (eye worm) nuclear hormone receptor family member nhr-40 0.0017 0.0063 0.0063
Entamoeba histolytica cysteine protease, putative 0.0243 0.2084 0.5377
Echinococcus multilocularis son of sevenless 1 0.0012 0.0016 0.0016
Mycobacterium tuberculosis Conserved protein 0.0036 0.0231 0.0999
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0442 0.3861 1
Onchocerca volvulus Netrin receptor homolog 0.0023 0.012 0.0247
Onchocerca volvulus 0.0442 0.3861 0.9064
Loa Loa (eye worm) CYP4Cod1 0.0025 0.0138 0.0138
Echinococcus multilocularis ras GTP exchange factor 0.0012 0.0016 0.0016
Trypanosoma brucei DNA polymerase kappa, putative 0.0041 0.0276 0.0279
Loa Loa (eye worm) hypothetical protein 0.0019 0.0079 0.0079
Echinococcus multilocularis cadherin EGF LAG seven pass G type receptor 0.0019 0.0079 0.0079
Trichomonas vaginalis penicillin-binding protein, putative 0.0036 0.0231 0.056
Trichomonas vaginalis Clan CA, family C1, papain-like cysteine peptidase 0.0442 0.3861 1
Entamoeba histolytica vacuolar protein sorting 26 0.0031 0.0193 0.046
Echinococcus granulosus protein cysteine N palmitoyltransferase 0.0031 0.0193 0.0193
Plasmodium vivax vivapain-2 0.0442 0.3861 1
Mycobacterium ulcerans DNA polymerase IV 0.0041 0.0276 1
Plasmodium vivax serine-repeat antigen 2 (SERA) 0.0107 0.0872 0.1851
Trypanosoma cruzi cruzipain precursor, putative 0.0136 0.1125 0.1111
Trichomonas vaginalis myo inositol monophosphatase, putative 0.0039 0.0257 0.0628
Loa Loa (eye worm) hypothetical protein 0.0036 0.0231 0.0231
Loa Loa (eye worm) hypothetical protein 0.0235 0.201 0.201
Loa Loa (eye worm) hypothetical protein 0.0306 0.2649 0.2649
Schistosoma mansoni netrin receptor unc5 0.0023 0.012 0.011
Brugia malayi MBOAT family protein 0.0031 0.0193 0.0177
Trypanosoma brucei DNA polymerase kappa, putative 0.0041 0.0276 0.0279
Schistosoma mansoni family S12 unassigned peptidase (S12 family) 0.0036 0.0231 0.0221
Trypanosoma brucei hypothetical protein, conserved 0.0036 0.0231 0.0233
Echinococcus multilocularis o acyltransferase (membrane bound) domain 0.0031 0.0193 0.0193
Schistosoma mansoni z-protein (S1r protein) 0.0016 0.0057 0.0047
Brugia malayi Papain family cysteine protease containing protein 0.0243 0.2084 0.2071
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.1114 0.9865 1
Brugia malayi TAR-binding protein 0.0063 0.0473 0.0458
Brugia malayi hypothetical protein 0.0016 0.0057 0.0042
Onchocerca volvulus 0.0442 0.3861 0.9064
Giardia lamblia Cathepsin B precursor 0.0423 0.3695 1
Onchocerca volvulus Segment polarity protein dishevelled homolog 0.0016 0.0057 0.0098
Echinococcus granulosus Pleckstrin G protein interacting region 0.0016 0.0057 0.0057
Plasmodium vivax serine-repeat antigen 4 (SERA) 0.0107 0.0872 0.1851
Toxoplasma gondii cathepsin B 0.0423 0.3695 0.9568
Echinococcus granulosus rap guanine nucleotide exchange factor 6 0.0012 0.0016 0.0016
Brugia malayi DIX domain containing protein 0.0016 0.0057 0.0042
Echinococcus multilocularis ecdysone induced protein 78C 0.0017 0.0063 0.0063
Entamoeba histolytica cysteine proteinase, putative 0.0243 0.2084 0.5377
Schistosoma mansoni cpg binding protein 0.0033 0.0211 0.02
Schistosoma mansoni ras GTP exchange factor son of sevenless 0.0012 0.0016 0.0005
Entamoeba histolytica cysteine protease, putative 0.0243 0.2084 0.5377
Trypanosoma brucei DNA polymerase kappa, putative 0.0041 0.0276 0.0279
Loa Loa (eye worm) hypothetical protein 0.0023 0.012 0.012
Leishmania major lanosterol 14-alpha-demethylase, putative 0.0017 0.0064 0.0023
Mycobacterium tuberculosis Probable cytochrome P450 141 Cyp141 0.0017 0.0064 0.012
Onchocerca volvulus 0.0442 0.3861 0.9064
Trichomonas vaginalis myo inositol monophosphatase, putative 0.0039 0.0257 0.0628
Trypanosoma cruzi cysteine peptidase, putative 0.0136 0.1125 0.1111
Loa Loa (eye worm) hypothetical protein 0.0017 0.0063 0.0063
Brugia malayi MBOAT family protein 0.0031 0.0193 0.0177
Trypanosoma cruzi cysteine peptidase, putative 0.1114 0.9865 0.9864
Trypanosoma cruzi Lanosterol 14-alpha demethylase 0.0017 0.0064 0.0048
Trichomonas vaginalis inositol monophosphatase, putative 0.0039 0.0257 0.0628
Schistosoma mansoni hypothetical protein 0.0048 0.0341 0.033
Leishmania major cathepsin L-like protease 0.0442 0.3861 0.3889
Loa Loa (eye worm) hypothetical protein 0.0026 0.0148 0.0148
Echinococcus multilocularis inositol monophosphatase 1 0.0039 0.0257 0.0257
Trypanosoma brucei DNA polymerase IV, putative 0.0041 0.0276 0.0279
Giardia lamblia Encystation-specific protease 0.0107 0.0872 0.2148
Schistosoma mansoni lozenge 0.0061 0.0458 0.0448
Plasmodium vivax hypothetical protein, conserved 0.0036 0.0231 0.0106
Trypanosoma cruzi cysteine proteinase, putative 0.0243 0.2084 0.2071
Schistosoma mansoni nuclear hormone receptor nor-1/nor-2 0.0017 0.0063 0.0053
Schistosoma mansoni jun-related protein 0.0063 0.048 0.0469
Plasmodium falciparum serine repeat antigen 4 0.0107 0.0872 0.1851
Echinococcus multilocularis regulator of G protein signaling 7 0.0016 0.0057 0.0057
Loa Loa (eye worm) runx1 0.0061 0.0458 0.0458
Mycobacterium tuberculosis Probable cytochrome P450 140 Cyp140 0.0017 0.0064 0.012
Schistosoma mansoni SmCB2 peptidase (C01 family) 0.1129 1 1
Schistosoma mansoni hypothetical protein 0.0086 0.0685 0.0675
Mycobacterium tuberculosis Probable cytochrome P450 128 Cyp128 0.0017 0.0064 0.012
Brugia malayi hypothetical protein 0.0016 0.0057 0.0042
Loa Loa (eye worm) hypothetical protein 0.0031 0.0193 0.0193
Loa Loa (eye worm) inositol-1 0.0039 0.0257 0.0257
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0442 0.3861 1
Brugia malayi cathepsin Z-like cysteine proteinase 0.0107 0.0872 0.0857
Leishmania major glycerol uptake protein, putative 0.0031 0.0193 0.0154
Leishmania major glycerol uptake protein, putative 0.0031 0.0193 0.0154
Onchocerca volvulus 0.0016 0.0057 0.0098
Plasmodium vivax unspecified product 0.0107 0.0872 0.1851
Trichomonas vaginalis DNA polymerase eta, putative 0.0041 0.0276 0.0677
Mycobacterium tuberculosis Possible penicillin-binding protein 0.0228 0.1947 1
Entamoeba histolytica membrane-bound O-acyltransferase (MBOAT ) family protein 0.0031 0.0193 0.046
Echinococcus multilocularis GPCR, family 2 0.0019 0.0079 0.0079
Loa Loa (eye worm) diacylglycerol acyltransferase 0.0031 0.0193 0.0193
Trypanosoma brucei DNA polymerase kappa, putative 0.0041 0.0276 0.0279
Plasmodium vivax serine-repeat antigen 5 (SERA) 0.0107 0.0872 0.1851
Echinococcus granulosus rap guanine nucleotide exchange factor 1 0.0012 0.0016 0.0016
Onchocerca volvulus 0.0442 0.3861 0.9064
Schistosoma mansoni inositol monophosphatase 0.0039 0.0257 0.0247
Trichomonas vaginalis Clan CA, family C1, papain-like cysteine peptidase 0.0442 0.3861 1
Schistosoma mansoni retinoid-x-receptor (RXR) 0.0017 0.0063 0.0053
Mycobacterium tuberculosis Probable lipase LipD 0.0036 0.0231 0.0999
Echinococcus multilocularis diuretic hormone 44 receptor GPRdih2 0.0199 0.169 0.169
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0306 0.2649 0.6848
Echinococcus multilocularis Nuclear hormone receptor family member nhr 41 0.0017 0.0063 0.0063
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0442 0.3861 1
Schistosoma mansoni subfamily C1A non-peptidase homologue (C01 family) 0.0107 0.0872 0.0862
Plasmodium vivax dipeptidyl aminopeptidase 1, putative 0.0107 0.0872 0.1851
Entamoeba histolytica hypothetical protein, conserved 0.0031 0.0193 0.046
Brugia malayi follicle stimulating hormone receptor 0.0219 0.1872 0.1859
Brugia malayi cathepsin Z-like cysteine proteinase 0.0107 0.0872 0.0857
Mycobacterium tuberculosis Probable hydrolase 0.0036 0.0231 0.0999
Brugia malayi ImpB/MucB/SamB family protein 0.0014 0.0041 0.0025
Echinococcus multilocularis sterol O acyltransferase 1 0.032 0.2776 0.2776
Loa Loa (eye worm) hypothetical protein 0.0136 0.1125 0.1125
Brugia malayi Papain family cysteine protease containing protein 0.0243 0.2084 0.2071
Brugia malayi Nuclear hormone receptor family member nhr-19 0.0017 0.0063 0.0048
Echinococcus multilocularis dna polymerase kappa 0.0041 0.0276 0.0276
Echinococcus granulosus Basic leucine zipper bZIP transcription 0.0036 0.0232 0.0232
Brugia malayi cathepsin F-like cysteine proteinase 0.0136 0.1125 0.1111
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.1114 0.9865 1
Onchocerca volvulus Rap guanine nucleotide exchange factor 1 homolog 0.0328 0.2847 0.6674
Loa Loa (eye worm) nuclear hormone receptor family member nhr-1 0.0017 0.0063 0.0063
Trypanosoma brucei DNA polymerase kappa, putative 0.0041 0.0276 0.0279
Loa Loa (eye worm) hypothetical protein 0.0486 0.4258 0.4258
Mycobacterium tuberculosis Probable cytochrome P450 139 Cyp139 0.0017 0.0064 0.012
Brugia malayi cathepsin L-like cysteine proteinase 0.0107 0.0872 0.0857
Trypanosoma brucei inositol-1(or 4)-monophosphatase 1, putative 0.0039 0.0257 0.026
Echinococcus granulosus cathepsin L cysteine proteinase 0.0442 0.3861 0.3861
Brugia malayi beta-lactamase family protein 0.0036 0.0231 0.0216
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0442 0.3861 1
Loa Loa (eye worm) hypothetical protein 0.0017 0.0063 0.0063
Brugia malayi Nuclear hormone receptor-like 1 0.0017 0.0063 0.0048
Schistosoma mansoni guanine-nucleotide-exchange-factor 0.0012 0.0016 0.0005
Brugia malayi hypothetical protein 0.0486 0.4258 0.4249
Loa Loa (eye worm) hypothetical protein 0.0013 0.0028 0.0028
Loa Loa (eye worm) cysteine protease 0.0442 0.3861 0.3861
Giardia lamblia Cysteine protease 0.0107 0.0872 0.2148
Mycobacterium tuberculosis Probable lipase LipE 0.0036 0.0231 0.0999
Entamoeba histolytica myo-inositol monophosphatase, putative 0.0039 0.0257 0.0628
Onchocerca volvulus Protein ultraspiracle homolog 0.0017 0.0063 0.0112
Leishmania major DNA polymerase kappa, putative,DNA polymerase IV, putative 0.0021 0.0099 0.0059
Toxoplasma gondii cytochrome p450 superfamily protein 0.0017 0.0064 0.0137
Echinococcus granulosus regulator of G protein signaling 7 0.0016 0.0057 0.0057
Echinococcus multilocularis survival motor neuron protein 1 0.0235 0.201 0.201
Leishmania major cathepsin L-like protease 0.0442 0.3861 0.3889
Mycobacterium tuberculosis Probable cytochrome P450 130 Cyp130 0.0017 0.0064 0.012
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0107 0.0872 0.2226
Giardia lamblia Cathepsin B precursor 0.0423 0.3695 1
Leishmania major glycerol uptake protein, putative 0.0031 0.0193 0.0154
Schistosoma mansoni subfamily C1A unassigned peptidase (C01 family) 0.0107 0.0872 0.0862
Loa Loa (eye worm) RNA recognition domain-containing protein domain-containing protein 0.0063 0.0473 0.0473
Trypanosoma cruzi DNA polymerase kappa, putative 0.0041 0.0276 0.0261
Echinococcus granulosus cpg binding protein 0.0033 0.0211 0.0211
Brugia malayi Latrophilin receptor protein 2 0.0019 0.0079 0.0063
Onchocerca volvulus 0.0036 0.0231 0.0508
Loa Loa (eye worm) pigment dispersing factor receptor c 0.0059 0.0437 0.0437
Trichomonas vaginalis D-aminoacylase, putative 0.0036 0.0231 0.056
Loa Loa (eye worm) cysteine proteinase cathepsin Z 0.0107 0.0872 0.0872
Brugia malayi Cathepsin L-like precursor 0.0306 0.2649 0.2638
Schistosoma mansoni diacylglycerol O-acyltransferase 1 0.0031 0.0193 0.0182
Loa Loa (eye worm) intermediate filament protein 0.0027 0.0152 0.0152
Echinococcus multilocularis cathepsin b 0.1129 1 1
Brugia malayi Papain family cysteine protease containing protein 0.0107 0.0872 0.0857
Loa Loa (eye worm) nuclear hormone receptor family member nhr-41 0.0017 0.0063 0.0063
Echinococcus granulosus retinoic acid receptor rxr beta a 0.0017 0.0063 0.0063
Schistosoma mansoni cathepsin B-like peptidase (C01 family) 0.0423 0.3695 0.3688
Trypanosoma cruzi cysteine peptidase (N-terminal), putative 0.0243 0.2084 0.2071
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0442 0.3861 1
Onchocerca volvulus Steroid hormone receptor family member cnr14 homolog 0.0017 0.0063 0.0112
Trichomonas vaginalis Clan CA, family C1, cathepsin H-like cysteine peptidase 0.0107 0.0872 0.2226
Giardia lamblia Cathepsin L precursor 0.0107 0.0872 0.2148
Loa Loa (eye worm) hypothetical protein 0.0036 0.0231 0.0231
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.1114 0.9865 1
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.1114 0.9865 1
Trypanosoma cruzi DNA polymerase eta, putative 0.0014 0.0041 0.0025
Trypanosoma cruzi cysteine peptidase C (CPC), putative 0.0423 0.3695 0.3685
Schistosoma mansoni cathepsin B-like peptidase (C01 family) 0.0107 0.0872 0.0862
Plasmodium vivax unspecified product 0.0136 0.1125 0.2541
Schistosoma mansoni hypothetical protein 0.0017 0.0064 0.0053
Echinococcus multilocularis Basic leucine zipper (bZIP) transcription 0.0036 0.0232 0.0232
Trypanosoma cruzi cysteine peptidase, putative 0.1114 0.9865 0.9864
Loa Loa (eye worm) latrophilin receptor protein 2 0.0019 0.0079 0.0079
Plasmodium falciparum cysteine proteinase falcipain 2a 0.0442 0.3861 1
Echinococcus granulosus cytoplasmic intermediate filament protein 0.0013 0.0028 0.0028
Plasmodium falciparum serine repeat antigen 6 0.0107 0.0872 0.1851
Brugia malayi cytoplasmic intermediate filament protein 0.0014 0.0041 0.0025
Trichomonas vaginalis D-aminoacylase, putative 0.0036 0.0231 0.056
Schistosoma mansoni o-acyltransferase (membrane bound) domain containing protein 0.0031 0.0193 0.0182
Trypanosoma cruzi cysteine peptidase, putative 0.0243 0.2084 0.2071
Trypanosoma brucei DNA polymerase eta, putative 0.0014 0.0041 0.004
Echinococcus granulosus cysteine protease 0.0243 0.2084 0.2084
Brugia malayi Hypothetical 52.5 kDa protein ZK945.1 in chromosome II, putative 0.0036 0.0231 0.0216
Giardia lamblia Cathepsin B precursor 0.0107 0.0872 0.2148
Loa Loa (eye worm) hypothetical protein 0.0036 0.0231 0.0231
Loa Loa (eye worm) hypothetical protein 0.0016 0.0057 0.0057
Entamoeba histolytica cysteine protease, putative 0.0107 0.0872 0.2226
Echinococcus granulosus dnaJ subfamily B 0.0449 0.3926 0.3926
Toxoplasma gondii acyl-CoA:cholesterol acyltransferase alpha ACAT1-alpha 0.0031 0.0193 0.0472
Entamoeba histolytica cysteine protease, putative 0.0243 0.2084 0.5377
Trypanosoma cruzi hypothetical protein, conserved 0.0036 0.0231 0.0216
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0442 0.3861 1
Schistosoma mansoni FTZ-F1 nuclear receptor-like protein 0.0017 0.0063 0.0053
Echinococcus granulosus cathepsin l1 0.0442 0.3861 0.3861
Brugia malayi MBOAT family protein 0.0031 0.0193 0.0177
Mycobacterium tuberculosis Probable cytochrome P450 125 Cyp125 0.0017 0.0064 0.012
Giardia lamblia Cathepsin B precursor 0.0107 0.0872 0.2148
Giardia lamblia Hypothetical protein 0.0107 0.0872 0.2148

Activities

Activity type Activity value Assay description Source Reference
Ki (binding) = 0.25 mM Inhibition constant (Ki) for human intestinal peptide carrier ChEMBL. 14667225

Phenotypes

Whole-cell/tissue/organism interactions

We have no records of whole-cell/tissue assays done with this compound What does this mean?

Many chemical entities in TDR Targets come from high-throughput screenings with whole cells or tissue samples, and not all assayed compounds have been tested against a single a single target protein, probably because they get ruled out during screening process. Even if these compounds may have not been of interest in the original screening, they may come as interesting leads for other screening assays. Furthermore, we may be able to propose drug-target associations using chemical similarities and network patterns.

Annotated phenotypes:

We have no manually annotated phenotypes for this drug. What does this mean? / Care to help?
In TDR Targets, information about phenotypes that are caused by drugs, or by genetic manipulation of cells (e.g. gene knockouts or knockdowns) is manually curated from the literature. These descriptions help to describe the potential of the target for drug development. If no information is available for this gene or if the information is incomplete, this may mean that i) the papers containing this information either appeared after the curation effort for this organism was carried out or they were inadvertently missed by curators; or that ii) the curation effort for this organism has not yet started.
 
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External resources for this compound

Bibliographic References

1 literature reference was collected for this gene.

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