Detailed information for compound 270616

Basic information

Technical information
  • Name: Unnamed compound
  • MW: 430.654 | Formula: C28H34O2Si
  • H donors: 2 H acceptors: 2 LogP: 6.88 Rotable bonds: 1
    Rule of 5 violations (Lipinski): 1
  • SMILES: Oc1ccc2c(c1)CCC1C2CCC2(C1CC[C@@]2(O)C#C[Si](c1ccccc1)(C)C)C
  • InChi: 1S/C28H34O2Si/c1-27-15-13-24-23-12-10-21(29)19-20(23)9-11-25(24)26(27)14-16-28(27,30)17-18-31(2,3)22-7-5-4-6-8-22/h4-8,10,12,19,24-26,29-30H,9,11,13-16H2,1-3H3/t24?,25?,26?,27?,28-/m1/s1
  • InChiKey: FWHUOIKQAUZDSP-PMLJOVNZSA-N  


Substructure search Similarity search

Network

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Synonyms

No synonyms found for this compound

Targets

Known targets for this compound

No curated genes were found associated with this compound

Predicted pathogen targets for this compound

By orthology
No druggable targets predicted by orthology data
By sequence similarity to non orthologous known druggable targets
No druggable targets predicted by sequence similarity
Obtained from network model

Ranking Plot

Putative Targets List

Species Potential target Raw Global Species
Mycobacterium tuberculosis Probable fatty-acid-CoA ligase FadD2 (fatty-acid-CoA synthetase) (fatty-acid-CoA synthase) 0.0024 0.0115 0.0317
Echinococcus granulosus pdz domain containing protein 0.0026 0.0142 0.0142
Loa Loa (eye worm) hypothetical protein 0.0026 0.0142 0.0206
Schistosoma mansoni afadin (af-6 protein) 0.0026 0.0142 0.0142
Echinococcus multilocularis pdz domain containing protein 0.0026 0.0142 0.0142
Schistosoma mansoni hypothetical protein 0.0026 0.0142 0.0142
Loa Loa (eye worm) hypothetical protein 0.0026 0.0142 0.0206
Loa Loa (eye worm) protein-tyrosine phosphatase 1 0.0026 0.0142 0.0206
Loa Loa (eye worm) hypothetical protein 0.0026 0.0142 0.0206
Loa Loa (eye worm) GTP-binding regulatory protein Gs alpha-S chain 0.0092 0.1116 0.1617
Echinococcus multilocularis guanine nucleotide binding protein G(s) subunit 0.0092 0.1116 0.1116
Loa Loa (eye worm) hypothetical protein 0.0026 0.0142 0.0206
Echinococcus multilocularis neurabin 1 0.0026 0.0142 0.0142
Mycobacterium tuberculosis Probable aldehyde dehydrogenase 0.0061 0.0664 0.2004
Mycobacterium tuberculosis Probable NADH dehydrogenase Ndh 0.0213 0.2914 0.8919
Toxoplasma gondii ferredoxin NADP+ oxidoreductase FNR 0.0055 0.0575 0.1565
Onchocerca volvulus 0.0026 0.0142 0.0088
Trypanosoma brucei NADH-dependent fumarate reductase, putative 0.0055 0.0575 0.0767
Brugia malayi Ferm domain 0.0026 0.0142 0.0206
Leishmania major cytochrome P450 reductase, putative 0.0428 0.6092 0.8816
Echinococcus granulosus NADPH cytochrome P450 reductase 0.0483 0.6904 0.6904
Leishmania major NADH-cytochrome b5 reductase, putative 0.0055 0.0575 0.0767
Echinococcus multilocularis partitioning defective 3 0.0026 0.0142 0.0142
Leishmania major myo-inositol-1(or 4)-monophosphatase 1, putative 0.0036 0.0294 0.0357
Mycobacterium tuberculosis Probable chain -fatty-acid-CoA ligase FadD13 (fatty-acyl-CoA synthetase) 0.0024 0.0115 0.0317
Mycobacterium tuberculosis Possible DNA-damage-inducible protein P DinP (DNA polymerase V) (pol IV 2) (DNA nucleotidyltransferase (DNA-directed)) 0.0019 0.0049 0.0116
Trichomonas vaginalis myo inositol monophosphatase, putative 0.0036 0.0294 0.0357
Toxoplasma gondii flavodoxin domain-containing protein 0.024 0.3306 1
Loa Loa (eye worm) DIX domain-containing protein 0.0026 0.0142 0.0206
Mycobacterium tuberculosis NADPH-dependent mycothiol reductase Mtr 0.0093 0.1144 0.3481
Trypanosoma brucei GTP-binding nuclear protein rtb2, putative 0.0021 0.0068 0.0028
Schistosoma mansoni syntenin 0.0026 0.0142 0.0142
Loa Loa (eye worm) hypothetical protein 0.003 0.0212 0.0307
Trypanosoma brucei NADH-cytochrome b5 reductase, putative 0.0055 0.0575 0.0767
Echinococcus multilocularis PDZ and LIM domain protein Zasp 0.0026 0.0142 0.0142
Schistosoma mansoni MAGUK homolog 0.0026 0.0147 0.0147
Echinococcus granulosus retinoic acid receptor rxr beta a 0.003 0.0212 0.0212
Plasmodium falciparum ataxin-2 like protein, putative 0.0025 0.0137 0.0162
Schistosoma mansoni dihydrolipoamide dehydrogenase 0.0032 0.0242 0.0242
Onchocerca volvulus 0.0036 0.0297 0.0577
Brugia malayi RNA, U transporter 1 0.008 0.0942 0.1365
Echinococcus granulosus syndecan binding protein syntenin 0.0026 0.0142 0.0142
Brugia malayi PDZ domain containing protein 0.0026 0.0142 0.0206
Brugia malayi hypothetical protein 0.0237 0.3271 0.4737
Echinococcus multilocularis pdz domain containing protein 0.0026 0.0142 0.0142
Echinococcus granulosus chromobox protein 1 0.007 0.0796 0.0796
Onchocerca volvulus Bile acid receptor homolog 0.003 0.0212 0.0308
Brugia malayi Nuclear hormone receptor family member nhr-14 0.003 0.0212 0.0307
Loa Loa (eye worm) nuclear hormone receptor family member nhr-14 0.003 0.0212 0.0307
Mycobacterium tuberculosis Probable nitrite reductase [NAD(P)H] large subunit [FAD flavoprotein] NirB 0.0213 0.2914 0.8919
Brugia malayi Nuclear hormone receptor family member nhr-1 0.003 0.0212 0.0307
Echinococcus granulosus chromobox protein 1 0.007 0.0796 0.0796
Mycobacterium tuberculosis Probable reductase 0.0213 0.2914 0.8919
Plasmodium falciparum glutathione reductase 0.0032 0.0242 0.0314
Trichomonas vaginalis Importin beta-1 subunit, putative 0.0023 0.0099 0.0073
Echinococcus granulosus amyloid beta A4 protein 0.0026 0.0142 0.0142
Trypanosoma cruzi NADH-dependent fumarate reductase, putative 0.0055 0.0575 0.0767
Brugia malayi hypothetical protein 0.0025 0.0137 0.0198
Leishmania major 4-coumarate:coa ligase-like protein 0.0024 0.0115 0.0095
Schistosoma mansoni chromobox protein 0.007 0.0796 0.0796
Loa Loa (eye worm) RasGEF domain-containing protein 0.0026 0.0142 0.0206
Trypanosoma cruzi PAB1-binding protein , putative 0.0025 0.0137 0.0128
Schistosoma mansoni multiple pdz domain protein 0.0026 0.0142 0.0142
Echinococcus granulosus myeloid:lymphoid or mixed lineage leukemia 0.0026 0.0142 0.0142
Echinococcus multilocularis importin subunit beta 1 0.0028 0.0178 0.0178
Wolbachia endosymbiont of Brugia malayi fructose-1,6-bisphosphatase 0.0036 0.0294 1
Trypanosoma brucei oxidoreductase-protein, putative 0.0055 0.0575 0.0767
Brugia malayi PX domain containing protein 0.0026 0.0142 0.0206
Plasmodium vivax ferredoxin--NADP reductase, putative 0.0055 0.0575 0.0798
Schistosoma mansoni nuclear receptor 2DBD-gamma 0.003 0.0212 0.0212
Trypanosoma brucei NADH-cytochrome b5 reductase, putative 0.0055 0.0575 0.0767
Trypanosoma cruzi dihydrolipoyl dehydrogenase, putative 0.0032 0.0242 0.0281
Loa Loa (eye worm) PDZ domain-containing protein 0.0026 0.0142 0.0206
Mycobacterium tuberculosis Probable oxidoreductase 0.0055 0.0575 0.1731
Trypanosoma brucei nitrate reductase, putative 0.0055 0.0575 0.0767
Echinococcus granulosus multiple pdz domain protein 0.0026 0.0142 0.0142
Loa Loa (eye worm) hypothetical protein 0.0026 0.0142 0.0206
Onchocerca volvulus 0.0026 0.0142 0.0088
Echinococcus granulosus dna polymerase kappa 0.0019 0.0049 0.0049
Toxoplasma gondii NADPH-glutathione reductase 0.0032 0.0242 0.0536
Brugia malayi AMP-binding enzyme family protein 0.0024 0.0115 0.0166
Brugia malayi gamma-syntrophin-like protein SYN2 0.0026 0.0142 0.0206
Echinococcus granulosus disks large 3 0.0026 0.0142 0.0142
Echinococcus granulosus glutamate receptor interacting protein 1 0.0026 0.0142 0.0142
Mycobacterium ulcerans acyl-CoA synthetase 0.0024 0.0115 0.0129
Mycobacterium tuberculosis Conserved protein 0.0036 0.0297 0.0878
Brugia malayi Hypothetical 52.5 kDa protein ZK945.1 in chromosome II, putative 0.0036 0.0297 0.043
Mycobacterium ulcerans formate dehydrogenase H FdhF 0.0483 0.6904 1
Loa Loa (eye worm) PX domain-containing protein 0.0026 0.0142 0.0206
Echinococcus granulosus membrane associated guanylate kinase, WW and PDZ 0.0026 0.0142 0.0142
Loa Loa (eye worm) hypothetical protein 0.0024 0.0115 0.0166
Treponema pallidum ferredoxin-NADP(+) reductase subunit alpha 0.0055 0.0575 0.1479
Echinococcus granulosus guanine nucleotide binding protein Gs subunit 0.0092 0.1116 0.1116
Brugia malayi Nuclear hormone receptor family member nhr-41 0.003 0.0212 0.0307
Echinococcus granulosus multiple pdz domain protein 0.0026 0.0142 0.0142
Mycobacterium ulcerans acyl-CoA synthetase 0.0024 0.0115 0.0129
Plasmodium falciparum thioredoxin reductase 0.0032 0.0242 0.0314
Toxoplasma gondii ABC1 family protein 0.0036 0.0297 0.0707
Loa Loa (eye worm) hypothetical protein 0.005 0.0502 0.0728
Leishmania major NADH-cytochrome b5 reductase, putative 0.0055 0.0575 0.0767
Loa Loa (eye worm) hypothetical protein 0.003 0.0212 0.0307
Mycobacterium tuberculosis Probable conserved lipoprotein 0.0036 0.0297 0.0878
Brugia malayi glutathione reductase 0.0093 0.1144 0.1657
Mycobacterium ulcerans extragenic suppressor protein SuhB 0.0036 0.0294 0.039
Echinococcus granulosus MAGUK p55 subfamily 0.0026 0.0142 0.0142
Loa Loa (eye worm) nuclear hormone receptor family member nhr-1 0.003 0.0212 0.0307
Trichomonas vaginalis conserved hypothetical protein 0.0039 0.0342 0.0428
Onchocerca volvulus 0.0031 0.0217 0.0324
Echinococcus multilocularis thioredoxin glutathione reductase 0.0093 0.1144 0.1144
Mycobacterium ulcerans aldehyde dehydrogenase 0.0061 0.0664 0.0927
Leishmania major dihydrolipoamide dehydrogenase, putative 0.0032 0.0242 0.0281
Loa Loa (eye worm) PAR-6 protein 0.0026 0.0142 0.0206
Trichomonas vaginalis set domain proteins, putative 0.0238 0.3277 0.4709
Echinococcus multilocularis protein piccolo 0.0026 0.0142 0.0142
Echinococcus granulosus PDZ and LIM domain protein Zasp 0.0026 0.0142 0.0142
Plasmodium vivax thioredoxin reductase, putative 0.0093 0.1144 0.1626
Echinococcus granulosus NADH cytochrome b5 reductase 3 0.0055 0.0575 0.0575
Echinococcus granulosus PRKCA binding protein 0.0026 0.0142 0.0142
Mycobacterium leprae conserved hypothetical protein 0.0036 0.0297 0.0579
Echinococcus granulosus ecdysone induced protein 78C 0.003 0.0212 0.0212
Schistosoma mansoni maguk P55 subfamily member 35 0.0026 0.0142 0.0142
Schistosoma mansoni cytochrome P450 reductase 0.0483 0.6904 0.6904
Trichomonas vaginalis CAMK family protein kinase 0.0095 0.1164 0.1627
Loa Loa (eye worm) hypothetical protein 0.0026 0.0142 0.0206
Brugia malayi Cytochrome b5-like Heme/Steroid binding domain containing protein 0.0055 0.0575 0.0832
Trichomonas vaginalis mercuric reductase, putative 0.0032 0.0242 0.0281
Loa Loa (eye worm) hypothetical protein 0.0483 0.6904 1
Plasmodium falciparum nitric oxide synthase, putative 0.0483 0.6904 1
Mycobacterium tuberculosis Hypothetical oxidoreductase 0.0055 0.0575 0.1731
Trichomonas vaginalis importin beta-1, putative 0.0023 0.0099 0.0073
Trichomonas vaginalis CAMK family protein kinase 0.0095 0.1164 0.1627
Schistosoma mansoni Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) 0.0092 0.1116 0.1116
Treponema pallidum flavodoxin 0.0185 0.2494 1
Entamoeba histolytica hypothetical protein 0.0023 0.0099 0.0204
Giardia lamblia Nitric oxide synthase, inducible 0.0428 0.6092 1
Loa Loa (eye worm) hypothetical protein 0.003 0.0212 0.0307
Echinococcus granulosus GTP binding nuclear protein Ran 0.0021 0.0068 0.0068
Loa Loa (eye worm) hypothetical protein 0.0026 0.0142 0.0206
Trypanosoma cruzi dihydrolipoamide dehydrogenase, putative 0.0032 0.0242 0.0281
Echinococcus multilocularis disks large 1 0.0026 0.0142 0.0142
Echinococcus granulosus dna polymerase eta 0.0045 0.0427 0.0427
Echinococcus multilocularis protein lin 7 B 0.0026 0.0142 0.0142
Loa Loa (eye worm) nuclear hormone receptor family member nhr-40 0.003 0.0212 0.0307
Echinococcus multilocularis amyloid beta A4 protein 0.0026 0.0142 0.0142
Echinococcus multilocularis serine:threonine protein kinase PLK1 0.0095 0.1164 0.1164
Loa Loa (eye worm) hypothetical protein 0.0036 0.0297 0.043
Onchocerca volvulus Heterochromatin protein 1 homolog 0.0042 0.0386 0.0859
Trypanosoma cruzi dihydrolipoyl dehydrogenase, putative 0.0032 0.0242 0.0281
Mycobacterium ulcerans DNA polymerase IV 0.0019 0.0049 0.0034
Mycobacterium tuberculosis Probable membrane NADH dehydrogenase NdhA 0.0213 0.2914 0.8919
Echinococcus granulosus 3'partial|membrane associated guanylate kinase ww and pdz 0.0026 0.0142 0.0142
Echinococcus multilocularis 55 kDa erythrocyte membrane protein 0.0026 0.0142 0.0142
Trichomonas vaginalis NADPH cytochrome P450, putative 0.0185 0.2494 0.3567
Mycobacterium tuberculosis Conserved protein 0.0036 0.0297 0.0878
Mycobacterium ulcerans flavodoxin oxidoreductase 0.0055 0.0575 0.0798
Brugia malayi serine/threonine-protein kinase plk-2 0.0095 0.1164 0.1686
Leishmania major hypothetical protein, conserved 0.0185 0.2494 0.3567
Onchocerca volvulus 0.0026 0.0142 0.0088
Onchocerca volvulus 0.0026 0.0142 0.0088
Onchocerca volvulus Serine\/threonine kinase homolog 0.0095 0.1164 0.3319
Plasmodium vivax dihydrolipoyl dehydrogenase, mitochondrial, putative 0.0032 0.0242 0.0314
Loa Loa (eye worm) hypothetical protein 0.0018 0.0026 0.0037
Trypanosoma brucei NADH-dependent fumarate reductase, putative 0.0055 0.0575 0.0767
Brugia malayi beta-lactamase family protein 0.0036 0.0297 0.043
Trichomonas vaginalis NADPH cytochrome P450, putative 0.0185 0.2494 0.3567
Plasmodium falciparum NADPH--cytochrome P450 reductase, putative 0.0185 0.2494 0.3589
Brugia malayi ImpB/MucB/SamB family protein 0.0019 0.0049 0.0071
Echinococcus multilocularis survival motor neuron protein 1 0.0237 0.3271 0.3271
Trichomonas vaginalis chromobox protein, putative 0.0042 0.0386 0.0492
Brugia malayi photoreceptor-specific nuclear receptor 0.003 0.0212 0.0307
Trypanosoma cruzi cytochrome-b5 reductase, putative 0.0055 0.0575 0.0767
Echinococcus granulosus neurabin 1 0.0026 0.0142 0.0142
Echinococcus granulosus disks large 1 0.0026 0.0142 0.0142
Mycobacterium ulcerans DNA polymerase IV 0.0019 0.0049 0.0034
Echinococcus granulosus tight junction protein ZO 3 0.0026 0.0142 0.0142
Brugia malayi hypothetical protein 0.0026 0.0142 0.0206
Schistosoma mansoni Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) 0.0092 0.1116 0.1116
Brugia malayi GTP-binding nuclear protein RAN/TC4 0.0021 0.0068 0.0099
Toxoplasma gondii aldehyde dehydrogenase 0.0061 0.0664 0.1839
Echinococcus granulosus Na:H exchange regulatory cofactor NHE RF2 0.0026 0.0142 0.0142
Brugia malayi RasGEF domain containing protein 0.0026 0.0142 0.0206
Loa Loa (eye worm) X11 protein 0.0026 0.0142 0.0206
Schistosoma mansoni amyloid beta A4 protein related 0.0026 0.0142 0.0142
Echinococcus multilocularis segment polarity protein dishevelled 0.0026 0.0142 0.0142
Chlamydia trachomatis dihydrolipoyl dehydrogenase 0.0032 0.0242 0.0521
Echinococcus granulosus histone lysine methyltransferase setb 0.003 0.0206 0.0206
Mycobacterium tuberculosis Putative ferredoxin reductase 0.0213 0.2914 0.8919
Echinococcus granulosus methionine synthase reductase 0.0298 0.4172 0.4172
Echinococcus multilocularis aldehyde dehydrogenase, mitochondrial 0.0061 0.0664 0.0664
Trichomonas vaginalis CAMK family protein kinase 0.0095 0.1164 0.1627
Brugia malayi hypothetical protein 0.0026 0.0142 0.0206
Brugia malayi PDZ domain containing protein 0.0026 0.0142 0.0206
Trypanosoma brucei dihydrolipoamide dehydrogenase 0.0032 0.0242 0.0281
Echinococcus multilocularis multiple pdz domain protein 0.0026 0.0142 0.0142
Echinococcus multilocularis 0.0026 0.0142 0.0142
Plasmodium falciparum dihydrolipoyl dehydrogenase, mitochondrial 0.0032 0.0242 0.0314
Plasmodium vivax NADPH-cytochrome p450 reductase, putative 0.0483 0.6904 1
Schistosoma mansoni nuclear hormone receptor 0.003 0.0212 0.0212
Schistosoma mansoni dishevelled 0.0026 0.0142 0.0142
Echinococcus granulosus serine:threonine protein kinase PLK1 0.0095 0.1164 0.1164
Onchocerca volvulus Arc homolog 0.0026 0.0142 0.0088
Giardia lamblia Flavohemoprotein lateral transfer candidate 0.0055 0.0575 0.087
Schistosoma mansoni MAGUK homolog 0.0026 0.0142 0.0142
Trypanosoma cruzi cytochrome P450 reductase, putative 0.0483 0.6904 1
Schistosoma mansoni ran 0.0021 0.0068 0.0068
Brugia malayi diaphorase 0.0055 0.0575 0.0832
Trichomonas vaginalis chromobox protein, putative 0.007 0.0796 0.109
Onchocerca volvulus 0.0048 0.0478 0.115
Echinococcus multilocularis PDZ and LIM domain protein Zasp 0.0026 0.0142 0.0142
Trypanosoma cruzi GTP-binding nuclear protein rtb2, putative 0.0021 0.0068 0.0028
Leishmania major trypanothione reductase 0.0093 0.1144 0.1598
Plasmodium vivax GTP-binding nuclear protein RAN/TC4, putative 0.0021 0.0068 0.0062
Trichomonas vaginalis myo inositol monophosphatase, putative 0.0036 0.0294 0.0357
Loa Loa (eye worm) hypothetical protein 0.0024 0.0115 0.0166
Echinococcus granulosus FTZ F1 nuclear receptor protein 0.003 0.0212 0.0212
Trypanosoma cruzi trypanothione reductase, putative 0.0093 0.1144 0.1598
Schistosoma mansoni hypothetical protein 0.0034 0.0268 0.0268
Loa Loa (eye worm) hypothetical protein 0.003 0.0206 0.0298
Trypanosoma cruzi dihydrolipoamide dehydrogenase, putative 0.0032 0.0242 0.0281
Brugia malayi Iron-sulfur cluster assembly accessory protein 0.0048 0.0478 0.0693
Trypanosoma cruzi NADPH--cytochrome P450 reductase, putative 0.0185 0.2494 0.3567
Loa Loa (eye worm) nuclear hormone receptor family member nhr-41 0.003 0.0212 0.0307
Echinococcus granulosus rho guanine nucleotide exchange factor 12 0.0026 0.0142 0.0142
Brugia malayi Nuclear hormone receptor family member nhr-25 0.003 0.0212 0.0307
Entamoeba histolytica type A flavoprotein, putative 0.0185 0.2494 1
Schistosoma mansoni membrane associated guanylate kinase inverted related 0.0026 0.0142 0.0142
Schistosoma mansoni histone-lysine n-methyltransferase setb1 0.003 0.0206 0.0206
Loa Loa (eye worm) hypothetical protein 0.0034 0.0268 0.0389
Schistosoma mansoni pdz domain containing protein 0.0026 0.0142 0.0142
Echinococcus multilocularis COUP TF:Svp nuclear hormone receptor 0.003 0.0212 0.0212
Trypanosoma brucei DNA polymerase eta, putative 0.0045 0.0427 0.0551
Brugia malayi beta-lactamase family protein 0.0036 0.0297 0.043
Schistosoma mansoni coup transcription factor 0.003 0.0212 0.0212
Schistosoma mansoni regulator of G protein signaling 0.0026 0.0142 0.0142
Trichomonas vaginalis NADPH cytochrome P450, putative 0.0185 0.2494 0.3567
Trichomonas vaginalis CAMK family protein kinase 0.0095 0.1164 0.1627
Echinococcus granulosus inositol monophosphatase 1 0.0036 0.0294 0.0294
Trichomonas vaginalis CAMK family protein kinase 0.0095 0.1164 0.1627
Trichomonas vaginalis CAMK family protein kinase 0.0095 0.1164 0.1627
Trypanosoma cruzi Flavodoxin/Radical SAM superfamily/Wyosine base formation, putative 0.0185 0.2494 0.3567
Mycobacterium ulcerans beta-lactamase 0.0036 0.0297 0.0394
Echinococcus multilocularis dna polymerase eta 0.0045 0.0427 0.0427
Trypanosoma cruzi NADPH-dependent FMN/FAD containing oxidoreductase, putative 0.0483 0.6904 1
Echinococcus multilocularis partitioning defective 3 0.0026 0.0142 0.0142
Brugia malayi rho guanine nucleotide exchange factor 12 0.0026 0.0142 0.0206
Mycobacterium ulcerans electron transfer protein FdxB 0.0055 0.0575 0.0798
Brugia malayi Protein-tyrosine phosphatase 1 0.0026 0.0142 0.0206
Brugia malayi Nuclear hormone receptor family member nhr-31 0.003 0.0212 0.0307
Loa Loa (eye worm) steroid hormone receptor 0.003 0.0212 0.0307
Onchocerca volvulus 0.0026 0.0147 0.0102
Trypanosoma brucei NADH-dependent fumarate reductase 0.0055 0.0575 0.0767
Echinococcus granulosus Nuclear hormone receptor family member nhr 41 0.003 0.0212 0.0212
Mycobacterium tuberculosis Possible oxygenase 0.0055 0.0575 0.1731
Echinococcus granulosus pdz domain containing protein 0.0026 0.0142 0.0142
Leishmania major acetoin dehydrogenase e3 component-like protein 0.0032 0.0242 0.0281
Giardia lamblia GTP-binding nuclear protein RAN/TC4 0.0021 0.0068 0.0031
Brugia malayi AMP-binding enzyme family protein 0.0024 0.0115 0.0166
Echinococcus multilocularis NADPH dependent diflavin oxidoreductase 1 0.0483 0.6904 0.6904
Trypanosoma brucei NADH-cytochrome b5 reductase-like protein 0.0055 0.0575 0.0767
Loa Loa (eye worm) hypothetical protein 0.0123 0.158 0.2289
Brugia malayi dihydrolipoyl dehydrogenase, mitochondrial precursor, putative 0.0032 0.0242 0.035
Schistosoma mansoni leucine-rich repeat protein 0.0026 0.0142 0.0142
Schistosoma mansoni rab3 interacting molecule (rim)-related 0.0026 0.0142 0.0142
Toxoplasma gondii flavodoxin domain-containing protein 0.024 0.3306 1
Echinococcus granulosus Microtubule-associated serine/threonine-protein kinase 0.0026 0.0147 0.0147
Entamoeba histolytica serine/threonine protein kinase, putative 0.0095 0.1164 0.456
Brugia malayi FAD binding domain containing protein 0.0298 0.4172 0.6043
Trypanosoma cruzi DNA polymerase eta, putative 0.0045 0.0427 0.0551
Brugia malayi microtubule-associated serine/threonine protein kinase 2 (MAST2) 0.0026 0.0142 0.0206
Entamoeba histolytica myo-inositol monophosphatase, putative 0.0036 0.0294 0.1002
Brugia malayi Pre-SET motif family protein 0.0209 0.285 0.4128
Schistosoma mansoni discs lost-related 0.0026 0.0142 0.0142
Mycobacterium ulcerans dihydrolipoamide dehydrogenase, LpdB 0.0032 0.0242 0.0314
Trypanosoma brucei NADH-cytochrome b5 reductase, putative 0.0055 0.0575 0.0767
Echinococcus multilocularis chromobox protein 1 0.007 0.0796 0.0796
Echinococcus granulosus 55 kDa erythrocyte membrane protein 0.0026 0.0142 0.0142
Giardia lamblia NADH oxidase lateral transfer candidate 0.0032 0.0242 0.0318
Echinococcus granulosus C2 calcium dependent membrane targeting 0.0026 0.0142 0.0142
Loa Loa (eye worm) hypothetical protein 0.0031 0.0217 0.0314
Loa Loa (eye worm) inositol-1 0.0036 0.0294 0.0426
Trypanosoma brucei inositol-1(or 4)-monophosphatase 1, putative 0.0036 0.0294 0.0357
Plasmodium falciparum NADH-cytochrome b5 reductase, putative 0.0055 0.0575 0.0798
Onchocerca volvulus 0.0026 0.0142 0.0088
Trypanosoma brucei PAB1-binding protein , putative 0.0025 0.0137 0.0128
Trypanosoma cruzi NADH-dependent fumarate reductase, putative 0.0055 0.0575 0.0767
Entamoeba histolytica Ran family GTPase 0.0021 0.0068 0.0077
Schistosoma mansoni serine/threonine protein kinase 0.0095 0.1164 0.1164
Onchocerca volvulus 0.0026 0.0142 0.0088
Echinococcus multilocularis disks large 3 0.0026 0.0142 0.0142
Trichomonas vaginalis sulfite reductase, putative 0.0483 0.6904 1
Echinococcus granulosus SH3 and multiple ankyrin repeat domains protein 0.0026 0.0142 0.0142
Echinococcus multilocularis glutamate receptor interacting protein 1 0.0026 0.0142 0.0142
Brugia malayi Pyridine nucleotide-disulphide oxidoreductase, dimerisation domain containing protein 0.0024 0.0114 0.0166
Plasmodium vivax oxidoreductase NAD-binding domain containing protein 0.0055 0.0575 0.0798
Schistosoma mansoni membrane associated guanylate kinase inverted related 0.0026 0.0142 0.0142
Brugia malayi Corticotropin releasing factor receptor 2 precursor, putative 0.005 0.0502 0.0728
Schistosoma mansoni regulator of G protein signaling 3 rgs3 0.0026 0.0142 0.0142
Echinococcus multilocularis chromobox protein 1 0.007 0.0796 0.0796
Loa Loa (eye worm) hypothetical protein 0.0025 0.0137 0.0198
Loa Loa (eye worm) hypothetical protein 0.0026 0.0142 0.0206
Brugia malayi Inositol-1 0.0036 0.0294 0.0426
Mycobacterium ulcerans aldehyde dehydrogenase 0.0061 0.0664 0.0927
Schistosoma mansoni Tr4/Tr2 (homologue) 0.003 0.0212 0.0212
Schistosoma mansoni lin-7-like proteins 0.0026 0.0142 0.0142
Loa Loa (eye worm) beta-lactamase 0.0036 0.0297 0.043
Onchocerca volvulus 0.0026 0.0142 0.0088
Echinococcus granulosus thioredoxin glutathione reductase 0.0093 0.1144 0.1144
Echinococcus granulosus survival motor neuron protein 1 0.0237 0.3271 0.3271
Echinococcus multilocularis multiple pdz domain protein 0.0026 0.0142 0.0142
Brugia malayi Shank2E 0.0026 0.0142 0.0206
Echinococcus multilocularis MAGUK p55 subfamily 0.0026 0.0142 0.0142
Echinococcus multilocularis GTP binding nuclear protein Ran 0.0021 0.0068 0.0068
Schistosoma mansoni histone-lysine n-methyltransferase setb1 0.003 0.0206 0.0206
Mycobacterium tuberculosis Probable esterase/lipase LipP 0.0036 0.0297 0.0878
Trypanosoma cruzi PAB1-binding protein , putative 0.0025 0.0137 0.0128
Schistosoma mansoni rab geranylgeranyl transferase alpha subunit 0.0019 0.0049 0.0049
Brugia malayi PDZ domain containing protein 0.0026 0.0142 0.0206
Schistosoma mansoni discs large 0.0026 0.0142 0.0142
Trypanosoma cruzi importin beta-1 subunit, putative 0.0023 0.0099 0.0073
Echinococcus granulosus peripheral plasma membrane protein CASK 0.0026 0.0147 0.0147
Loa Loa (eye worm) hypothetical protein 0.0026 0.0142 0.0206
Brugia malayi Pre-SET motif family protein 0.003 0.0206 0.0298
Trichomonas vaginalis CAMK family protein kinase 0.0047 0.0456 0.0594
Brugia malayi Nuclear hormone receptor family member nhr-25 0.003 0.0212 0.0307
Schistosoma mansoni cell polarity protein 0.0026 0.0142 0.0142
Echinococcus granulosus partitioning defective 3 0.0026 0.0142 0.0142
Loa Loa (eye worm) hypothetical protein 0.0026 0.0142 0.0206
Schistosoma mansoni hypothetical protein 0.0026 0.0142 0.0142
Loa Loa (eye worm) nuclear Hormone Receptor family member 0.003 0.0212 0.0307
Trypanosoma cruzi NADH-dependent fumarate reductase, putative 0.0055 0.0575 0.0767
Plasmodium vivax hypothetical protein, conserved 0.0036 0.0297 0.0394
Echinococcus multilocularis cytochrome b5 reductase 4 0.0055 0.0575 0.0575
Trichomonas vaginalis D-aminoacylase, putative 0.0036 0.0297 0.0362
Trypanosoma cruzi myo-inositol-1(or 4)-monophosphatase 1, putative 0.0036 0.0294 0.0357
Loa Loa (eye worm) ImpB/MucB/SamB family protein 0.0019 0.0049 0.0071
Trypanosoma brucei hypothetical protein, conserved 0.0036 0.0297 0.0362
Mycobacterium tuberculosis Probable monooxygenase 0.0055 0.0575 0.1731
Loa Loa (eye worm) hypothetical protein 0.0026 0.0142 0.0206
Brugia malayi Partitioning defective-6 homolog alpha 0.0026 0.0142 0.0206
Mycobacterium ulcerans esterase/lipase LipP 0.0036 0.0297 0.0394
Brugia malayi Abnormal embryonic partitioning of cytoplasm protein 3 0.0026 0.0142 0.0206
Mycobacterium ulcerans oxygenase 0.0055 0.0575 0.0798
Onchocerca volvulus 0.0238 0.3277 1
Trichomonas vaginalis glutathione reductase, putative 0.0032 0.0242 0.0281
Brugia malayi cell junction protein LIN-7 0.0026 0.0142 0.0206
Echinococcus multilocularis terminal deoxycytidyl transferase rev1 0.0019 0.0049 0.0049
Echinococcus granulosus nuclear receptor 2DBD gamma 0.003 0.0212 0.0212
Onchocerca volvulus 0.0026 0.0142 0.0088
Mycobacterium ulcerans hypothetical protein 0.0036 0.0297 0.0394
Echinococcus granulosus COUP TF:Svp nuclear hormone receptor 0.003 0.0212 0.0212
Echinococcus granulosus protein lin 7 B 0.0026 0.0142 0.0142
Brugia malayi latrophilin 2 splice variant baaae 0.0034 0.0268 0.0389
Echinococcus multilocularis syndecan binding protein (syntenin) 0.0026 0.0142 0.0142
Echinococcus granulosus Partitioning defective 3 protein B 0.0026 0.0142 0.0142
Echinococcus multilocularis inositol monophosphatase 1 0.0036 0.0294 0.0294
Echinococcus granulosus dihydrolipoamide dehydrogenase 0.0032 0.0242 0.0242
Mycobacterium tuberculosis Possible electron transfer protein FdxB 0.0055 0.0575 0.1731
Trypanosoma cruzi p450 reductase, putative 0.0055 0.0575 0.0767
Loa Loa (eye worm) hypothetical protein 0.0036 0.0297 0.043
Leishmania major oxidoreductase-like protein 0.0055 0.0575 0.0767
Onchocerca volvulus Heterochromatin protein 1 homolog 0.0039 0.0342 0.072
Trypanosoma brucei NADPH--cytochrome P450 reductase, putative 0.0483 0.6904 1
Schistosoma mansoni hypothetical protein 0.017 0.2277 0.2277
Onchocerca volvulus 0.0026 0.0142 0.0088
Echinococcus granulosus guanine nucleotide binding protein Gs subunit 0.0092 0.1116 0.1116
Brugia malayi Peripheral plasma membrane protein CASK 0.0026 0.0142 0.0206
Brugia malayi flavodoxin family protein 0.0185 0.2494 0.3613
Loa Loa (eye worm) PLK/PLK1 protein kinase 0.0095 0.1164 0.1686
Echinococcus granulosus membrane associated guanylate kinase ww and pdz 0.0026 0.0142 0.0142
Brugia malayi Nuclear hormone receptor family member nhr-49 0.003 0.0212 0.0307
Schistosoma mansoni hypothetical protein 0.017 0.2277 0.2277
Onchocerca volvulus Protein ultraspiracle homolog 0.003 0.0212 0.0308
Schistosoma mansoni hypothetical protein 0.0026 0.0142 0.0142
Loa Loa (eye worm) hypothetical protein 0.0026 0.0142 0.0206
Toxoplasma gondii NADH-cytochrome b5 reductase 1, putative 0.0055 0.0575 0.1565
Toxoplasma gondii thioredoxin reductase 0.0093 0.1144 0.3324
Loa Loa (eye worm) FAD binding domain-containing protein 0.0298 0.4172 0.6043
Loa Loa (eye worm) nuclear hormone receptor family member nhr-49 0.003 0.0212 0.0307
Schistosoma mansoni leucine-rich repeat protein 0.0026 0.0142 0.0142
Echinococcus granulosus Rho GTPase activating protein 21 0.0026 0.0142 0.0142
Loa Loa (eye worm) thioredoxin reductase 0.0093 0.1144 0.1657
Echinococcus multilocularis FTZ F1 nuclear receptor protein 0.003 0.0212 0.0212
Echinococcus granulosus importin subunit beta 1 0.0028 0.0178 0.0178
Echinococcus granulosus beta LACTamase domain containing family member 0.0036 0.0297 0.0297
Echinococcus multilocularis MAGUK p55 subfamily 0.0026 0.0142 0.0142
Loa Loa (eye worm) hypothetical protein 0.0018 0.0026 0.0037
Loa Loa (eye worm) hypothetical protein 0.0026 0.0142 0.0206
Brugia malayi Synapse defective protein 1 0.0026 0.0142 0.0206
Echinococcus granulosus segment polarity protein dishevelled 0.0026 0.0142 0.0142
Echinococcus granulosus PDZ and LIM domain protein Zasp 0.0026 0.0142 0.0142
Loa Loa (eye worm) heterochromatin protein 1 0.007 0.0796 0.1153
Schistosoma mansoni steroid hormone receptor ad4bp 0.003 0.0212 0.0212
Onchocerca volvulus 0.0036 0.0297 0.0577
Schistosoma mansoni survival motor neuron protein 0.0048 0.0478 0.0478
Trypanosoma cruzi cytochrome P450 reductase, putative 0.0483 0.6904 1
Mycobacterium ulcerans fatty-acid-CoA ligase 0.0024 0.0115 0.0129
Schistosoma mansoni retinoic acid receptor RXR 0.003 0.0212 0.0212
Schistosoma mansoni multiple pdz domain protein 0.0026 0.0142 0.0142
Schistosoma mansoni cytochrome B5 0.0055 0.0575 0.0575
Schistosoma mansoni NADPH flavin oxidoreductase 0.0243 0.3361 0.3361
Leishmania major nitrate reductase, putative 0.0055 0.0575 0.0767
Schistosoma mansoni hypothetical protein 0.0048 0.0478 0.0478
Trichomonas vaginalis inositol monophosphatase, putative 0.0036 0.0294 0.0357
Loa Loa (eye worm) hypothetical protein 0.003 0.0212 0.0307
Onchocerca volvulus 0.0026 0.0142 0.0088
Brugia malayi alpha keto acid dehydrogenase complex, E3 component, lipoamide dehydrogenase 0.0024 0.0114 0.0166
Schistosoma mansoni terminal deoxycytidyl transferase 0.0019 0.0049 0.0049
Trypanosoma cruzi NADH-dependent fumarate reductase, putative 0.0055 0.0575 0.0767
Echinococcus multilocularis membrane associated guanylate kinase, WW and PDZ 0.0026 0.0142 0.0142
Echinococcus multilocularis pdz domain containing protein 0.0026 0.0142 0.0142
Brugia malayi hypothetical protein 0.0026 0.0142 0.0206
Brugia malayi Heterochromatin protein 1 0.007 0.0796 0.1153
Loa Loa (eye worm) hypothetical protein 0.003 0.0212 0.0307
Leishmania major hypothetical protein, conserved 0.0036 0.0297 0.0362
Loa Loa (eye worm) hypothetical protein 0.0018 0.0026 0.0037
Schistosoma mansoni microtubule-associated protein tau 0.0692 1 1
Trypanosoma cruzi myo-inositol-1(or 4)-monophosphatase 1, putative 0.0036 0.0294 0.0357
Trypanosoma cruzi hypothetical protein, conserved 0.0036 0.0297 0.0362
Brugia malayi Steroid receptor seven-up type 2 0.003 0.0212 0.0307
Echinococcus granulosus 5'partial|histone lysine N methyltransferase SETDB2 0.0029 0.0189 0.0189
Loa Loa (eye worm) syntrophin-1 0.0026 0.0142 0.0206
Loa Loa (eye worm) glutathione reductase 0.0093 0.1144 0.1657
Leishmania major cytochrome-b5 reductase, putative 0.0055 0.0575 0.0767
Loa Loa (eye worm) hypothetical protein 0.0026 0.0142 0.0206
Echinococcus granulosus hepatocyte nuclear factor 4 alpha 0.003 0.0212 0.0212
Echinococcus multilocularis NADPH cytochrome P450 reductase 0.0483 0.6904 0.6904
Trypanosoma brucei polo-like protein kinase 0.0095 0.1164 0.1627
Loa Loa (eye worm) hypothetical protein 0.0018 0.0026 0.0037
Schistosoma mansoni diflavin oxidoreductase 0.024 0.3306 0.3306
Toxoplasma gondii HEAT repeat-containing protein 0.0028 0.0178 0.0338
Echinococcus multilocularis ecdysone induced protein 78C 0.003 0.0212 0.0212
Loa Loa (eye worm) hypothetical protein 0.003 0.0212 0.0307
Trypanosoma brucei NADPH--cytochrome P450 reductase, putative 0.0483 0.6904 1
Schistosoma mansoni protein kinase C alpha binding protein 0.0026 0.0142 0.0142
Echinococcus granulosus aldehyde dehydrogenase mitochondrial 0.0061 0.0664 0.0664
Brugia malayi hypothetical protein 0.0026 0.0142 0.0206
Mycobacterium tuberculosis Possible penicillin-binding protein 0.0231 0.3175 0.9721
Trypanosoma brucei NADH-cytochrome b5 reductase, putative 0.0055 0.0575 0.0767
Trypanosoma cruzi dihydrolipoamide dehydrogenase, putative 0.0032 0.0242 0.0281
Echinococcus multilocularis rho guanine nucleotide exchange factor 12 0.0026 0.0142 0.0142
Schistosoma mansoni multiple pdz domain protein 0.0026 0.0142 0.0142
Echinococcus multilocularis SH3 and multiple ankyrin repeat domains protein 0.0026 0.0142 0.0142
Loa Loa (eye worm) diaphorase 0.0055 0.0575 0.0832
Trypanosoma brucei NADH-dependent fumarate reductase 0.0055 0.0575 0.0767
Schistosoma mansoni NADH-cytochrome B5 reductase 0.0055 0.0575 0.0575
Plasmodium falciparum glutathione reductase 0.0093 0.1144 0.1626
Brugia malayi protein kinase C-binding protein PICK1 0.0026 0.0142 0.0206
Loa Loa (eye worm) hypothetical protein 0.0026 0.0142 0.0206
Leishmania major NADH-dependent fumarate reductase, putative 0.0055 0.0575 0.0767
Toxoplasma gondii histone lysine methyltransferase SET/SUV39 0.003 0.0206 0.0425
Mycobacterium tuberculosis Probable lipase LipE 0.0036 0.0297 0.0878
Brugia malayi PDZ domain 0.0026 0.0142 0.0206
Schistosoma mansoni inositol monophosphatase 0.0036 0.0294 0.0294
Echinococcus multilocularis multiple pdz domain protein 0.0026 0.0142 0.0142
Brugia malayi Patj homolog 0.0026 0.0142 0.0206
Schistosoma mansoni photoreceptor-specific nuclear receptor related 0.003 0.0212 0.0212
Brugia malayi DIX domain containing protein 0.0026 0.0142 0.0206
Loa Loa (eye worm) hypothetical protein 0.0036 0.0297 0.043
Schistosoma mansoni hypothetical protein 0.0026 0.0142 0.0142
Schistosoma mansoni 5-methyl tetrahydrofolate-homocysteine methyltransferase reductase 0.0298 0.4172 0.4172
Mycobacterium ulcerans long-chain-fatty-acid-CoA ligase 0.0024 0.0115 0.0129
Brugia malayi ImpB/MucB/SamB family protein 0.0045 0.0427 0.0618
Loa Loa (eye worm) hypothetical protein 0.0026 0.0142 0.0206
Brugia malayi syntenin 0.0026 0.0142 0.0206
Schistosoma mansoni family S12 unassigned peptidase (S12 family) 0.0036 0.0297 0.0297
Trypanosoma cruzi GTP-binding nuclear protein rtb2, putative 0.0021 0.0068 0.0028
Brugia malayi AMP-binding enzyme family protein 0.0024 0.0115 0.0166
Schistosoma mansoni ran 0.0021 0.0068 0.0068
Schistosoma mansoni lim domain 0.0026 0.0142 0.0142
Schistosoma mansoni PDZ domain protein 0.0026 0.0142 0.0142
Echinococcus multilocularis Nuclear hormone receptor family member nhr 41 0.003 0.0212 0.0212
Trypanosoma cruzi NADH-dependent fumarate reductase, putative 0.0055 0.0575 0.0767
Leishmania major 4-coumarate:coa ligase-like protein 0.0024 0.0115 0.0095
Schistosoma mansoni hypothetical protein 0.0026 0.0142 0.0142
Mycobacterium tuberculosis Conserved hypothetical protein 0.0019 0.0049 0.0116
Brugia malayi Guanylate kinase family protein 0.0026 0.0142 0.0206
Loa Loa (eye worm) hypothetical protein 0.0026 0.0142 0.0206
Brugia malayi PDZ-domain protein scribble 0.0026 0.0142 0.0206
Leishmania major dihydrolipoamide dehydrogenase, putative 0.0032 0.0242 0.0281
Schistosoma mansoni hypothetical protein 0.0026 0.0142 0.0142
Echinococcus granulosus multiple pdz domain protein 0.0026 0.0142 0.0142
Brugia malayi Domain found in Dishevelled, Egl-10, and Pleckstrin family protein 0.0026 0.0142 0.0206
Brugia malayi PDZ domain containing protein 0.0026 0.0142 0.0206
Brugia malayi steroid hormone receptor 0.003 0.0212 0.0307
Trypanosoma brucei dihydrolipoamide dehydrogenase 0.0032 0.0242 0.0281
Brugia malayi PDZ domain 0.0026 0.0142 0.0206
Onchocerca volvulus Big bang homolog 0.0026 0.0142 0.0088
Echinococcus granulosus PDZ and LIM domain protein Zasp 0.0026 0.0142 0.0142
Echinococcus granulosus terminal deoxycytidyl transferase rev1 0.0019 0.0049 0.0049
Loa Loa (eye worm) guanylate kinase 0.0026 0.0142 0.0206
Loa Loa (eye worm) hypothetical protein 0.0026 0.0142 0.0206
Echinococcus multilocularis tyrosine protein phosphatase non receptor type 0.0026 0.0142 0.0142
Schistosoma mansoni thyroid hormone receptor 0.003 0.0212 0.0212
Entamoeba histolytica acyl-CoA synthetase, putative 0.0024 0.0115 0.0268
Brugia malayi Thioredoxin reductase 0.0093 0.1144 0.1657
Chlamydia trachomatis Na(+)-translocating NADH-quinone reductase subunit F 0.0055 0.0575 0.1324
Trichomonas vaginalis penicillin-binding protein, putative 0.0036 0.0297 0.0362
Schistosoma mansoni Patj homolog 0.0026 0.0142 0.0142
Schistosoma mansoni DNA polymerase eta 0.0045 0.0427 0.0427
Trypanosoma cruzi dihydrolipoamide dehydrogenase, putative 0.0032 0.0242 0.0281
Echinococcus multilocularis microtubule associated serine:threonine protein 0.0026 0.0147 0.0147
Echinococcus multilocularis PRKCA binding protein 0.0026 0.0142 0.0142
Toxoplasma gondii inositol(myo)-1(or 4)-monophosphatase 2, putative 0.0036 0.0294 0.0698
Leishmania major NADH-cytochrome b5 reductase, putative 0.0055 0.0575 0.0767
Loa Loa (eye worm) hypothetical protein 0.0123 0.158 0.2289
Plasmodium falciparum S-adenosyl-L-methionine-dependent tRNA 4-demethylwyosine synthase, putative 0.0185 0.2494 0.3589
Plasmodium falciparum ataxin-2 like protein, putative 0.0025 0.0137 0.0162
Schistosoma mansoni multiple pdz domain protein 0.0026 0.0142 0.0142
Plasmodium vivax SET domain protein, putative 0.003 0.0206 0.0262
Chlamydia trachomatis sulfite reductase 0.0298 0.4172 1
Echinococcus multilocularis C2 calcium dependent membrane targeting 0.0026 0.0142 0.0142
Echinococcus multilocularis cell polarity protein leucine rich repeat 0.0026 0.0142 0.0142
Giardia lamblia Hypothetical protein 0.0428 0.6092 1
Mycobacterium leprae possible inositol monophosphatase SubH (IMPase) (inositol-1-phosphatase) (I-1-Pase ). 0.0032 0.0238 0.0393
Echinococcus multilocularis membrane associated guanylate kinase ww and pdz 0.0026 0.0142 0.0142
Trypanosoma cruzi DNA polymerase eta, putative 0.0032 0.023 0.0263
Brugia malayi beta-lactamase 0.0036 0.0297 0.043
Schistosoma mansoni maguk P55 subfamily member 26 0.0026 0.0142 0.0142
Brugia malayi Nuclear hormone receptor-like 1 0.003 0.0212 0.0307
Mycobacterium ulcerans acyl-CoA synthetase 0.0024 0.0115 0.0129
Leishmania major DNA polymerase eta, putative 0.0032 0.023 0.0263
Loa Loa (eye worm) hypothetical protein 0.0026 0.0142 0.0206
Echinococcus multilocularis partitioning defective protein 6 0.0026 0.0142 0.0142
Loa Loa (eye worm) guanylate kinase 0.0026 0.0142 0.0206
Chlamydia trachomatis tail-specific protease 0.0026 0.0142 0.0282
Echinococcus multilocularis myeloid:lymphoid or mixed lineage leukemia 0.0026 0.0142 0.0142
Trypanosoma brucei dihydrolipoyl dehydrogenase 0.0032 0.0242 0.0281
Loa Loa (eye worm) flavodoxin family protein 0.0185 0.2494 0.3613
Schistosoma mansoni importin beta-1 0.0028 0.0178 0.0178
Trypanosoma brucei dihydrolipoamide dehydrogenase, point mutation 0.0032 0.0242 0.0281
Loa Loa (eye worm) hypothetical protein 0.0026 0.0142 0.0206
Echinococcus granulosus ligand of numb protein x 2 0.0026 0.0142 0.0142
Brugia malayi Hypothetical 13.5 kDa protein C45G9.7 in chromosome III 0.0026 0.0142 0.0206
Echinococcus multilocularis MAGUK p55 subfamily 0.0026 0.0142 0.0142
Echinococcus multilocularis dna polymerase kappa 0.0019 0.0049 0.0049
Brugia malayi Guanylate kinase family protein 0.0026 0.0142 0.0206
Echinococcus granulosus SH3 and multiple ankyrin repeat domains protein 0.0026 0.0142 0.0142
Trypanosoma cruzi p450 reductase, putative 0.0483 0.6904 1
Mycobacterium ulcerans aldehyde dehydrogenase 0.0061 0.0664 0.0927
Echinococcus multilocularis segment polarity protein dishevelled 0.0026 0.0142 0.0142
Schistosoma mansoni cell polarity protein 0.0026 0.0142 0.0142
Brugia malayi Nuclear hormone receptor family member nhr-3 0.003 0.0212 0.0307
Leishmania major p450 reductase, putative 0.0483 0.6904 1
Trypanosoma brucei importin beta-1 subunit, putative 0.0028 0.0178 0.0187
Brugia malayi hypothetical protein 0.0016 0.0004 0.0006
Mycobacterium tuberculosis Inositol-1-monophosphatase SuhB 0.0032 0.0238 0.0698
Schistosoma mansoni chromobox protein 0.007 0.0796 0.0796
Plasmodium vivax dihydrolipoyl dehydrogenase, apicoplast, putative 0.0032 0.0242 0.0314
Brugia malayi abnormal cell lineage protein 10 (Protein lin-10), putative 0.0026 0.0142 0.0206
Loa Loa (eye worm) hypothetical protein 0.0028 0.0178 0.0257
Plasmodium vivax glutathione reductase, putative 0.0093 0.1144 0.1626
Loa Loa (eye worm) hypothetical protein 0.0026 0.0142 0.0206
Mycobacterium tuberculosis Probable lipase LipD 0.0036 0.0297 0.0878
Schistosoma mansoni hypothetical protein 0.0026 0.0142 0.0142
Onchocerca volvulus Huntingtin homolog 0.0123 0.158 0.4635
Echinococcus granulosus SH3 and multiple ankyrin repeat domains protein 0.0026 0.0142 0.0142
Trypanosoma brucei NADPH-dependent diflavin oxidoreductase 1 0.0483 0.6904 1
Loa Loa (eye worm) hypothetical protein 0.0018 0.0026 0.0037
Giardia lamblia Kinase, PLK 0.0095 0.1164 0.1845
Brugia malayi Neurabin protein 1 0.0026 0.0142 0.0206
Mycobacterium ulcerans lipase LipD 0.0036 0.0297 0.0394
Schistosoma mansoni cell polarity protein 0.0026 0.0142 0.0142
Loa Loa (eye worm) hypothetical protein 0.0026 0.0142 0.0206
Mycobacterium tuberculosis Conserved protein 0.0036 0.0297 0.0878
Echinococcus granulosus nuclear receptor 2DBD gamma 0.003 0.0212 0.0212
Brugia malayi Syntrophin-1 0.0026 0.0142 0.0206
Echinococcus multilocularis methionine synthase reductase 0.0298 0.4172 0.4172
Brugia malayi FAD binding domain containing protein 0.0483 0.6904 1
Brugia malayi 9ORF binding protein 1 0.0026 0.0142 0.0206
Trypanosoma cruzi polo-like protein kinase, putative 0.0095 0.1164 0.1627
Trichomonas vaginalis Importin beta-1 subunit, putative 0.0023 0.0099 0.0073
Trichomonas vaginalis conserved hypothetical protein 0.0039 0.0342 0.0428
Schistosoma mansoni nuclear hormone receptor nor-1/nor-2 0.003 0.0212 0.0212
Schistosoma mansoni hypothetical protein 0.0026 0.0142 0.0142
Echinococcus granulosus segment polarity protein dishevelled 0.0026 0.0142 0.0142
Onchocerca volvulus Steroid hormone receptor family member cnr14 homolog 0.003 0.0212 0.0308
Schistosoma mansoni hypothetical protein 0.0026 0.0142 0.0142
Trypanosoma brucei trypanothione reductase 0.0093 0.1144 0.1598
Echinococcus multilocularis NADH cytochrome b5 reductase 3 0.0055 0.0575 0.0575
Brugia malayi hypothetical protein 0.0026 0.0142 0.0206
Echinococcus granulosus cytochrome b5 reductase 4 0.0055 0.0575 0.0575
Echinococcus multilocularis PDZ domain containing protein GIPC3 0.0026 0.0142 0.0142
Echinococcus multilocularis guanine nucleotide binding protein G(s) subunit 0.0092 0.1116 0.1116
Mycobacterium ulcerans long-chain-fatty-acid--CoA ligase 0.0024 0.0115 0.0129
Brugia malayi gopc protein 0.0026 0.0142 0.0206
Plasmodium vivax importin-beta 2, putative 0.0028 0.0178 0.0221
Echinococcus multilocularis Rho GTPase activating protein 21 0.0026 0.0142 0.0142
Leishmania major NADH-dependent fumarate reductase-like protein 0.0055 0.0575 0.0767
Loa Loa (eye worm) AGC/MAST/MAST protein kinase 0.0026 0.0147 0.0213
Trichomonas vaginalis conserved hypothetical protein 0.0028 0.0173 0.0181
Leishmania major importin beta-1 subunit, putative 0.0023 0.0099 0.0073
Onchocerca volvulus 0.0036 0.0297 0.0577
Echinococcus multilocularis histone lysine methyltransferase setb histone lysine methyltransferase eggless 0.003 0.0206 0.0206
Plasmodium falciparum GTP-binding nuclear protein RAN/TC4 0.0021 0.0068 0.0062
Plasmodium vivax ataxin-2 like protein, putative 0.0025 0.0137 0.0162
Echinococcus granulosus pdz domain containing protein 0.0026 0.0142 0.0142
Echinococcus granulosus pdz domain containing protein 0.0026 0.0142 0.0142
Trypanosoma cruzi oxidoreductase-like protein, putative 0.0055 0.0575 0.0767
Mycobacterium tuberculosis Dihydrolipoamide dehydrogenase LpdC (lipoamide reductase (NADH)) (lipoyl dehydrogenase) (dihydrolipoyl dehydrogenase) (diaphoras 0.0237 0.3266 1
Trichomonas vaginalis CAMK family protein kinase 0.0095 0.1164 0.1627
Loa Loa (eye worm) hypothetical protein 0.0237 0.3271 0.4737
Schistosoma mansoni aldehyde dehydrogenase 0.0061 0.0664 0.0664
Loa Loa (eye worm) cell junction protein LIN-7 0.0026 0.0142 0.0206
Plasmodium falciparum dihydrolipoyl dehydrogenase, apicoplast 0.0032 0.0242 0.0314
Mycobacterium ulcerans flavodoxin reductase Hmp 0.0055 0.0575 0.0798
Loa Loa (eye worm) FAD binding domain-containing protein 0.0483 0.6904 1
Mycobacterium tuberculosis NAD(P)H quinone reductase LpdA 0.0237 0.3266 1
Mycobacterium tuberculosis Probable esterase LipL 0.0036 0.0297 0.0878
Echinococcus multilocularis FTZ F1 alpha 0.003 0.0212 0.0212
Loa Loa (eye worm) hypothetical protein 0.0024 0.0115 0.0166
Trypanosoma cruzi polo-like protein kinase, putative 0.0095 0.1164 0.1627
Mycobacterium ulcerans flavoprotein disulfide reductase 0.0032 0.0242 0.0314
Mycobacterium tuberculosis Probable dehydrogenase 0.0213 0.2914 0.8919
Loa Loa (eye worm) hypothetical protein 0.0036 0.0297 0.043
Schistosoma mansoni family S12 unassigned peptidase (S12 family) 0.0036 0.0297 0.0297
Leishmania major NADPH-cytochrome p450 reductase-like protein 0.0483 0.6904 1
Trichomonas vaginalis D-aminoacylase, putative 0.0036 0.0297 0.0362
Loa Loa (eye worm) hypothetical protein 0.0045 0.0427 0.0618
Plasmodium falciparum ferredoxin--NADP reductase 0.0055 0.0575 0.0798
Schistosoma mansoni hypothetical protein 0.0026 0.0142 0.0142
Echinococcus granulosus membrane associated guanylate kinase ww and pdz 0.0026 0.0142 0.0142
Brugia malayi nuclear receptor NHR-88 0.003 0.0212 0.0307
Loa Loa (eye worm) 9ORF binding protein 1 0.0026 0.0142 0.0206
Entamoeba histolytica acyl-coA synthetase, putative 0.0024 0.0115 0.0268
Schistosoma mansoni retinoid-x-receptor (RXR) 0.003 0.0212 0.0212
Echinococcus granulosus NADPH dependent diflavin oxidoreductase 1 0.0483 0.6904 0.6904
Onchocerca volvulus Segment polarity protein dishevelled homolog 0.0026 0.0142 0.0088
Loa Loa (eye worm) beta-LACTamase domain containing family member 0.0036 0.0297 0.043
Plasmodium vivax hypothetical protein, conserved 0.0185 0.2494 0.3589
Toxoplasma gondii ImpB/MucB/SamB family protein 0.0032 0.023 0.0499
Brugia malayi nuclear hormone receptor 0.003 0.0212 0.0307
Loa Loa (eye worm) hypothetical protein 0.0026 0.0142 0.0206
Schistosoma mansoni histone-lysine n-methyltransferase suv9 0.0041 0.0375 0.0375
Schistosoma mansoni pdz and lim domain protein 0.0026 0.0142 0.0142
Loa Loa (eye worm) hypothetical protein 0.0036 0.0297 0.043
Trichomonas vaginalis esterase, putative 0.0036 0.0297 0.0362
Mycobacterium leprae PROBABLE NADH DEHYDROGENASE NDH 0.0213 0.2914 0.8884
Echinococcus granulosus MAGUK p55 subfamily 0.0026 0.0142 0.0142
Leishmania major protein kinase, putative,polo-like protein kinase, putative 0.0095 0.1164 0.1627
Echinococcus multilocularis geminin 0.017 0.2277 0.2277
Trichomonas vaginalis D-aminoacylase, putative 0.0036 0.0297 0.0362
Schistosoma mansoni thyroid hormone receptor 0.003 0.0212 0.0212
Schistosoma mansoni kinase 0.0048 0.0475 0.0475
Leishmania major reductase, putative 0.0055 0.0575 0.0767
Echinococcus granulosus partitioning defective 3 0.0026 0.0142 0.0142
Brugia malayi hypothetical protein 0.0026 0.0142 0.0206
Trypanosoma cruzi nitrate reductase, putative 0.0055 0.0575 0.0767
Trypanosoma cruzi dihydrolipoamide dehydrogenase, putative 0.0032 0.0242 0.0281
Schistosoma mansoni aldehyde dehydrogenase 0.0061 0.0664 0.0664
Loa Loa (eye worm) PDZ-domain-containing protein scribble 0.0026 0.0142 0.0206
Entamoeba histolytica type A flavoprotein, putative 0.0185 0.2494 1
Trichomonas vaginalis ran, putative 0.0021 0.0068 0.0028
Leishmania major 2-oxoglutarate dehydrogenase, e3 component, lipoamidedehydrogenase-like protein 0.0032 0.0242 0.0281
Schistosoma mansoni histone-lysine n-methyltransferase setb1 0.003 0.0206 0.0206
Brugia malayi hypothetical protein 0.0123 0.158 0.2289
Echinococcus multilocularis beta LACTamase domain containing family member 0.0036 0.0297 0.0297
Mycobacterium ulcerans long-chain fatty-acid CoA ligase 0.0024 0.0115 0.0129
Echinococcus multilocularis SH3 and multiple ankyrin repeat domains protein 0.0026 0.0142 0.0142
Echinococcus granulosus tyrosine protein phosphatase non receptor type 0.0026 0.0142 0.0142
Loa Loa (eye worm) hypothetical protein 0.0026 0.0142 0.0206
Trypanosoma cruzi hypothetical protein, conserved 0.0036 0.0297 0.0362
Brugia malayi Nuclear hormone receptor family member nhr-40 0.003 0.0212 0.0307
Trypanosoma cruzi NADH-cytochrome b5 reductase, putative 0.0055 0.0575 0.0767
Schistosoma mansoni hypothetical protein 0.0026 0.0142 0.0142
Brugia malayi Nuclear hormone receptor family member nhr-19 0.003 0.0212 0.0307
Echinococcus multilocularis PDZ and LIM domain protein Zasp 0.0026 0.0142 0.0142
Mycobacterium ulcerans fusion of enoyl-CoA hydratase, EchA21 and lipase, LipE 0.0036 0.0297 0.0394
Echinococcus multilocularis SH3 and multiple ankyrin repeat domains protein 0.0026 0.0142 0.0142
Brugia malayi Ligand-binding domain of nuclear hormone receptor family protein 0.003 0.0212 0.0307
Trypanosoma cruzi reductase, putative 0.0055 0.0575 0.0767
Trypanosoma cruzi cytochrome-b5 reductase, putative 0.0055 0.0575 0.0767
Entamoeba histolytica type A flavoprotein, putative 0.0185 0.2494 1
Schistosoma mansoni ATP-dependent RNA Helicase 0.0026 0.0142 0.0142
Leishmania major cytochrome-b5 reductase, putative 0.0055 0.0575 0.0767
Brugia malayi chromobox protein homolog 3 0.0039 0.0342 0.0496
Loa Loa (eye worm) hypothetical protein 0.0026 0.0142 0.0206
Schistosoma mansoni dishevelled 0.0026 0.0142 0.0142
Onchocerca volvulus Huntingtin homolog 0.0123 0.158 0.4635
Loa Loa (eye worm) hypothetical protein 0.0026 0.0142 0.0206
Trichomonas vaginalis NADPH fad oxidoreductase, putative 0.0428 0.6092 0.8816
Echinococcus multilocularis hepatocyte nuclear factor 4 alpha 0.003 0.0212 0.0212
Loa Loa (eye worm) pigment dispersing factor receptor c 0.005 0.0502 0.0728
Entamoeba histolytica acyl-CoA synthetase, putative 0.0024 0.0115 0.0268
Toxoplasma gondii pyruvate dehydrogenase complex subunit PDH-E3II 0.0032 0.0242 0.0536
Echinococcus granulosus geminin 0.017 0.2277 0.2277
Mycobacterium tuberculosis Probable hydrolase 0.0036 0.0297 0.0878
Trichomonas vaginalis chromobox protein, putative 0.0042 0.0386 0.0492
Loa Loa (eye worm) hypothetical protein 0.0026 0.0142 0.0206
Schistosoma mansoni sap-97 0.0026 0.0142 0.0142
Mycobacterium leprae DIHYDROLIPOAMIDE DEHYDROGENASE LPD (LIPOAMIDE REDUCTASE (NADH)) (LIPOYL DEHYDROGENASE) (DIHYDROLIPOYL DEHYDROGENASE) (DIAPHORASE 0.0237 0.3266 1
Echinococcus multilocularis nuclear receptor 2DBD gamma 0.003 0.0212 0.0212
Loa Loa (eye worm) hypothetical protein 0.003 0.0212 0.0307
Echinococcus multilocularis nuclear receptor 2DBD gamma 0.003 0.0212 0.0212
Trichomonas vaginalis NADPH cytochrome P450, putative 0.0185 0.2494 0.3567
Mycobacterium ulcerans monooxygenase 0.0055 0.0575 0.0798
Loa Loa (eye worm) hypothetical protein 0.0026 0.0142 0.0206
Entamoeba histolytica type A flavoprotein, putative 0.0185 0.2494 1
Echinococcus multilocularis dihydrolipoamide dehydrogenase 0.0032 0.0242 0.0242
Leishmania major DNA polymerase eta, putative 0.0045 0.0427 0.0551
Echinococcus multilocularis Partitioning defective 3 protein B 0.0026 0.0142 0.0142
Loa Loa (eye worm) hypothetical protein 0.003 0.0212 0.0307
Schistosoma mansoni tight junction protein 0.0026 0.0142 0.0142
Toxoplasma gondii LsmAD domain-containing protein 0.0025 0.0137 0.0212
Echinococcus granulosus snurportin 1 0.0299 0.419 0.419
Echinococcus granulosus cytochrome b5 reductase 4 0.0055 0.0575 0.0575
Leishmania major aldehyde dehydrogenase, mitochondrial precursor 0.0061 0.0664 0.0896
Brugia malayi ecdysteroid receptor 0.003 0.0212 0.0307
Mycobacterium ulcerans hypothetical protein 0.0024 0.0115 0.0129
Schistosoma mansoni sh3 and multiple ankyrin repeat domains protein 12 (shank12) 0.0026 0.0142 0.0142
Echinococcus multilocularis thyroid hormone receptor alpha 0.003 0.0212 0.0212
Plasmodium falciparum thioredoxin reductase 0.0093 0.1144 0.1626
Entamoeba histolytica type A flavoprotein, putative 0.0185 0.2494 1
Schistosoma mansoni syntrophin 0.0026 0.0142 0.0142
Trypanosoma cruzi Flavodoxin/Radical SAM superfamily/Wyosine base formation, putative 0.0185 0.2494 0.3567
Trypanosoma cruzi NADH-cytochrome b5 reductase, putative 0.0055 0.0575 0.0767
Mycobacterium tuberculosis Probable soluble pyridine nucleotide transhydrogenase SthA (STH) (NAD(P)(+) transhydrogenase [B-specific]) (nicotinamide nucleot 0.0032 0.0242 0.0708
Trypanosoma cruzi NADH-cytochrome b5 reductase, putative 0.0055 0.0575 0.0767
Plasmodium falciparum importin beta, putative 0.0028 0.0178 0.0221
Schistosoma mansoni RAR-like nuclear receptor 0.003 0.0212 0.0212
Trypanosoma cruzi oxidoreductase-protein, putative 0.0055 0.0575 0.0767
Loa Loa (eye worm) nucleolar RNA-associated protein alpha 0.0299 0.419 0.6069
Echinococcus granulosus MAGUK p55 subfamily 0.0026 0.0142 0.0142
Schistosoma mansoni inositol monophosphatase 0.0036 0.0294 0.0294
Echinococcus granulosus beta 1 syntrophin 0.0026 0.0142 0.0142
Schistosoma mansoni membrane associated guanylate kinase inverted related 0.0026 0.0142 0.0142
Echinococcus multilocularis microtubule associated protein 2 0.0692 1 1
Echinococcus granulosus cell polarity protein 0.0026 0.0142 0.0142
Echinococcus multilocularis pdz domain containing protein 0.0026 0.0142 0.0142
Trypanosoma brucei NADPH-cytochrome p450 reductase, putative 0.0483 0.6904 1
Leishmania major 4-coumarate:coa ligase-like protein 0.0024 0.0115 0.0095
Brugia malayi Importin beta-1 subunit 0.0028 0.0178 0.0257
Trypanosoma brucei NADH-cytochrome b5 reductase, putative 0.0055 0.0575 0.0767
Brugia malayi GTP-binding regulatory protein Gs alpha-S chain, putative 0.0092 0.1116 0.1617
Echinococcus granulosus FTZ F1 alpha 0.003 0.0212 0.0212
Brugia malayi flavodoxin family protein 0.0483 0.6904 1
Leishmania major hypothetical protein, conserved 0.0025 0.0137 0.0128
Trypanosoma cruzi NADH-cytochrome b5 reductase, putative 0.0055 0.0575 0.0767
Schistosoma mansoni cell polarity protein 0.0026 0.0142 0.0142
Loa Loa (eye worm) nuclear hormone receptor family member nhr-31 0.003 0.0212 0.0307
Brugia malayi Nuclear hormone receptor family member nhr-19 0.003 0.0212 0.0307
Mycobacterium ulcerans dihydrolipoamide dehydrogenase 0.0032 0.0242 0.0314
Echinococcus multilocularis ligand of numb protein x 2 0.0026 0.0142 0.0142
Trypanosoma brucei importin beta-1 subunit, putative 0.0028 0.0178 0.0187
Echinococcus multilocularis tight junction protein ZO 3 0.0026 0.0142 0.0142
Leishmania major GTP-binding protein, putative 0.0021 0.0068 0.0028
Loa Loa (eye worm) pre-SET domain-containing protein family protein 0.0209 0.285 0.4128
Echinococcus multilocularis Na(+):H(+) exchange regulatory cofactor NHE RF2 0.0026 0.0142 0.0142
Brugia malayi Calcitonin receptor-like protein seb-1 0.005 0.0502 0.0728
Loa Loa (eye worm) hypothetical protein 0.0026 0.0142 0.0206
Trichomonas vaginalis chromobox protein, putative 0.007 0.0796 0.109
Echinococcus multilocularis glutamate receptor interacting protein 1 0.0026 0.0142 0.0142
Trypanosoma cruzi trypanothione reductase, putative 0.0032 0.0242 0.0281
Mycobacterium tuberculosis Possible conserved lipoprotein LpqK 0.0036 0.0297 0.0878
Echinococcus multilocularis histone lysine N methyltransferase SETMAR 0.003 0.0206 0.0206
Schistosoma mansoni FTZ-F1 nuclear receptor-like protein 0.003 0.0212 0.0212
Brugia malayi interleukin-16 0.0026 0.0142 0.0206
Echinococcus multilocularis snurportin 1 0.0299 0.419 0.419
Schistosoma mansoni hypothetical protein 0.0299 0.419 0.419
Loa Loa (eye worm) peripheral plasma membrane protein CASK 0.0026 0.0142 0.0206
Schistosoma mansoni Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) 0.0092 0.1116 0.1116
Trichomonas vaginalis conserved hypothetical protein 0.0028 0.0173 0.0181
Loa Loa (eye worm) gopc protein 0.0026 0.0142 0.0206
Trypanosoma cruzi NADH-cytochrome b5 reductase, putative 0.0055 0.0575 0.0767
Onchocerca volvulus 0.003 0.0212 0.0308
Trypanosoma cruzi NADH-cytochrome b5 reductase, putative 0.0055 0.0575 0.0767
Schistosoma mansoni multiple pdz domain protein 0.0026 0.0142 0.0142
Loa Loa (eye worm) GTP-binding nuclear protein RAN/TC4 0.0021 0.0068 0.0099
Brugia malayi Ligand-binding domain of nuclear hormone receptor family protein 0.003 0.0212 0.0307
Trypanosoma cruzi NADH-dependent fumarate reductase, putative 0.0055 0.0575 0.0767
Echinococcus multilocularis beta 1 syntrophin 0.0026 0.0142 0.0142
Loa Loa (eye worm) cytochrome b5 reductase 4 0.0055 0.0575 0.0832
Onchocerca volvulus 0.0041 0.0375 0.0823
Mycobacterium tuberculosis Probable oxidoreductase 0.0237 0.3266 1
Loa Loa (eye worm) hypothetical protein 0.0036 0.0297 0.043
Schistosoma mansoni hypothetical protein 0.0026 0.0142 0.0142
Schistosoma mansoni pdz domain containing protein 0.0026 0.0142 0.0142
Trichomonas vaginalis CAMK family protein kinase 0.0047 0.0456 0.0594
Loa Loa (eye worm) hypothetical protein 0.0026 0.0142 0.0206
Brugia malayi C2 domain containing protein 0.0026 0.0142 0.0206
Echinococcus multilocularis peripheral plasma membrane protein CASK 0.0026 0.0147 0.0147
Onchocerca volvulus 0.0055 0.0575 0.1455
Trypanosoma cruzi dihydrolipoamide dehydrogenase, putative 0.0032 0.0242 0.0281
Mycobacterium ulcerans oxidoreductase 0.0055 0.0575 0.0798
Trypanosoma brucei NADH-cytochrome b5 reductase, putative 0.0055 0.0575 0.0767
Mycobacterium leprae Probable lipase LipE 0.0036 0.0297 0.0579
Mycobacterium tuberculosis Fatty-acid-AMP ligase FadD30 (fatty-acid-AMP synthetase) (fatty-acid-AMP synthase) 0.0018 0.0026 0.0044
Trichomonas vaginalis penicillin-binding protein, putative 0.0036 0.0297 0.0362
Loa Loa (eye worm) hypothetical protein 0.0039 0.0342 0.0496
Trypanosoma brucei S-adenosyl-L-methionine-dependent tRNA 4-demethylwyosine synthase, putative 0.0185 0.2494 0.3567
Plasmodium vivax flavodoxin domain containing protein 0.0428 0.6092 0.882

Activities

Activity type Activity value Assay description Source Reference
Antifertility potency (functional) = 33 Antifertility activity measured as minimum protective dose for prevention of pregnancy in rats ChEMBL. 3560158
Estrogenic potency (functional) = 7 Evaluation of oral estrogenic activity by using immature female rats ovariectomized at 21 days of age. ChEMBL. 3560158
Separation (functional) = 4.7 Separation of antifertility from estrogenic activity in rats was measured ChEMBL. 3560158

Phenotypes

Whole-cell/tissue/organism interactions

We have no records of whole-cell/tissue assays done with this compound What does this mean?

Many chemical entities in TDR Targets come from high-throughput screenings with whole cells or tissue samples, and not all assayed compounds have been tested against a single a single target protein, probably because they get ruled out during screening process. Even if these compounds may have not been of interest in the original screening, they may come as interesting leads for other screening assays. Furthermore, we may be able to propose drug-target associations using chemical similarities and network patterns.

Annotated phenotypes:

We have no manually annotated phenotypes for this drug. What does this mean? / Care to help?
In TDR Targets, information about phenotypes that are caused by drugs, or by genetic manipulation of cells (e.g. gene knockouts or knockdowns) is manually curated from the literature. These descriptions help to describe the potential of the target for drug development. If no information is available for this gene or if the information is incomplete, this may mean that i) the papers containing this information either appeared after the curation effort for this organism was carried out or they were inadvertently missed by curators; or that ii) the curation effort for this organism has not yet started.
 
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External resources for this compound

Bibliographic References

1 literature reference was collected for this gene.

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