Detailed information for compound 280423

Basic information

Technical information
  • Name: Unnamed compound
  • MW: 367.895 | Formula: C21H24ClN4-
  • H donors: 1 H acceptors: 2 LogP: 4.51 Rotable bonds: 8
    Rule of 5 violations (Lipinski): 1
  • SMILES: CN(Cc1ccccc1)CCCNc1ccc(nn1)c1ccccc1.[Cl-]
  • InChi: 1S/C21H24N4.ClH/c1-25(17-18-9-4-2-5-10-18)16-8-15-22-21-14-13-20(23-24-21)19-11-6-3-7-12-19;/h2-7,9-14H,8,15-17H2,1H3,(H,22,24);1H/p-1
  • InChiKey: NNHYJZAGKKPICP-UHFFFAOYSA-M  


Substructure search Similarity search

Network

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Synonyms

No synonyms found for this compound

Targets

Known targets for this compound

No curated genes were found associated with this compound

Predicted pathogen targets for this compound

By orthology
No druggable targets predicted by orthology data
By sequence similarity to non orthologous known druggable targets
No druggable targets predicted by sequence similarity
Obtained from network model

Ranking Plot

Putative Targets List

Species Potential target Raw Global Species
Loa Loa (eye worm) glutaminase 0.0314 0.0936 0.3024
Loa Loa (eye worm) nuclear hormone receptor family member nhr-49 0.0062 0.0148 0.0475
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0035 0.0065 0.0319
Echinococcus multilocularis mitogen activated protein kinase 3 0.0116 0.0315 0.0314
Brugia malayi MH2 domain containing protein 0.0017 0.0008 0.0023
Trichomonas vaginalis chromodomain helicase DNA binding protein, putative 0.0015 0.000000000034474 0.00000000017026
Trypanosoma cruzi cysteine peptidase, putative 0.0135 0.0376 0.0553
Echinococcus granulosus Nuclear hormone receptor HR96 0.0029 0.0045 0.0092
Toxoplasma gondii LsmAD domain-containing protein 0.0029 0.0044 0.0414
Loa Loa (eye worm) CYP4Cod1 0.0034 0.0059 0.0187
Echinococcus granulosus ankyrin repeat and death domain containing protein 0.0017 0.0006 0.001
Brugia malayi Papain family cysteine protease containing protein 0.0018 0.0011 0.0033
Loa Loa (eye worm) hypothetical protein 0.0023 0.0026 0.008
Loa Loa (eye worm) hypothetical protein 0.0128 0.0354 0.1144
Schistosoma mansoni family S9 non-peptidase homologue (S09 family) 0.0123 0.0338 0.0695
Toxoplasma gondii inositol(myo)-1(or 4)-monophosphatase 2, putative 0.0042 0.0087 0.0813
Brugia malayi Carboxylesterase family protein 0.0021 0.0019 0.0058
Toxoplasma gondii melibiase subfamily protein 0.0118 0.0322 0.3042
Brugia malayi multidrug resistance protein 3 0.0024 0.003 0.0094
Brugia malayi Nuclear hormone receptor family member nhr-40 0.0062 0.0148 0.0475
Echinococcus granulosus histone lysine N methyltransferase MLL3 0.0017 0.0008 0.0016
Schistosoma mansoni Tr4/Tr2 (homologue) 0.0062 0.0148 0.0303
Loa Loa (eye worm) hypothetical protein 0.0029 0.0045 0.0144
Trichomonas vaginalis DNA helicase recq, putative 0.003 0.0046 0.0229
Echinococcus multilocularis transcription factor btf3 0.004 0.0079 0.0079
Loa Loa (eye worm) hypothetical protein 0.0029 0.0045 0.0144
Schistosoma mansoni smad1 5 8 and 0.0017 0.0008 0.0015
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0035 0.0065 0.0319
Loa Loa (eye worm) hypothetical protein 0.0068 0.0165 0.0533
Echinococcus multilocularis atpase aaa+ type core atpase aaa type core 0.0815 0.2499 0.2499
Loa Loa (eye worm) beta-LACTamase domain containing family member 0.0041 0.0083 0.0267
Loa Loa (eye worm) hypothetical protein 0.0029 0.0045 0.0144
Echinococcus granulosus lysine specific demethylase 6a 0.0036 0.0065 0.0133
Onchocerca volvulus Huntingtin homolog 0.0106 0.0285 0.0907
Schistosoma mansoni survival motor neuron protein 0.0055 0.0127 0.0261
Echinococcus granulosus Nuclear hormone receptor HR96 0.0029 0.0045 0.0092
Echinococcus granulosus cathepsin L 0.0018 0.0011 0.0021
Schistosoma mansoni acetylcholinesterase 0.0021 0.0019 0.0037
Schistosoma mansoni hypothetical protein 0.0103 0.0277 0.057
Echinococcus multilocularis lipoxygenase domain containing protein 0.0064 0.0155 0.0154
Schistosoma mansoni multidrug resistance protein 0.0024 0.003 0.006
Trichomonas vaginalis Clan CD, family C14, metacaspase-like cysteine peptidase 0.002 0.0017 0.0086
Loa Loa (eye worm) hypothetical protein 0.0029 0.0045 0.0144
Echinococcus granulosus jumonji domain containing 1A 0.0036 0.0065 0.0133
Leishmania major basic transcription factor 3a, putative 0.004 0.0079 0.0116
Plasmodium vivax vivapain-2 0.0035 0.0065 0.0884
Schistosoma mansoni hypothetical protein 0.0041 0.0083 0.017
Echinococcus granulosus family S9 non peptidase ue S09 family 0.0021 0.0019 0.0037
Onchocerca volvulus 0.0021 0.0019 0.0043
Echinococcus granulosus organic anion transporting polypeptide 30B 0.0128 0.0354 0.073
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0135 0.0376 0.0553
Leishmania major cathepsin L-like protease 0.0135 0.0376 0.0553
Trypanosoma cruzi DNA polymerase beta thumb, putative 0.0308 0.0915 0.1347
Echinococcus granulosus Solute carrier organic anion transporter family 0.0128 0.0354 0.073
Schistosoma mansoni lozenge 0.0126 0.0348 0.0716
Schistosoma mansoni histone-lysine n-methyltransferase setb1 0.0036 0.0066 0.0134
Echinococcus multilocularis organic anion transporting polypeptide 30B 0.0128 0.0354 0.0354
Loa Loa (eye worm) hypothetical protein 0.0033 0.0056 0.018
Brugia malayi cathepsin L-like precursor 0.0024 0.0028 0.0088
Echinococcus multilocularis BC026374 protein (S09 family) 0.0021 0.0019 0.0018
Trypanosoma cruzi cysteine proteinase, putative 0.0018 0.0011 0.0015
Trichomonas vaginalis ABC transporter, putative 0.0024 0.003 0.0146
Trypanosoma cruzi mitochondrial DNA polymerase beta-PAK, putative 0.0375 0.1125 0.1657
Mycobacterium ulcerans fusion of enoyl-CoA hydratase, EchA21 and lipase, LipE 0.0041 0.0083 0.0232
Brugia malayi ATP-dependent DNA helicase, RecQ family protein 0.0027 0.0038 0.0119
Loa Loa (eye worm) carboxylesterase 0.0021 0.0019 0.0058
Trypanosoma cruzi transcription factor btf3, putative 0.004 0.0079 0.0116
Brugia malayi Nuclear hormone receptor family member nhr-25 0.0062 0.0148 0.0475
Loa Loa (eye worm) hypothetical protein 0.0024 0.0028 0.0088
Echinococcus granulosus 5'partial|histone lysine N methyltransferase SETDB2 0.0033 0.0057 0.0117
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0018 0.0011 0.0015
Trichomonas vaginalis Clan CD, family C14, metacaspase-like cysteine peptidase 0.002 0.0017 0.0086
Trichomonas vaginalis glucosylceramidase, putative 0.0195 0.0562 0.2778
Schistosoma mansoni alpha-galactosidase/alpha-n-acetylgalactosaminidase 0.0118 0.0322 0.0663
Echinococcus multilocularis mitogen activated protein kinase 0.0116 0.0315 0.0314
Onchocerca volvulus Protein ultraspiracle homolog 0.0062 0.0148 0.0461
Echinococcus granulosus ATP dependent DNA helicase Q5 0.0027 0.0038 0.0076
Onchocerca volvulus 0.0024 0.0028 0.0073
Onchocerca volvulus 0.0029 0.0045 0.0129
Leishmania major cysteine peptidase A (CPA) 0.0035 0.0065 0.0094
Brugia malayi hypothetical protein 0.0029 0.0044 0.0141
Brugia malayi sodium-independent organic anion transporter family protein 0.0128 0.0354 0.1144
Trichomonas vaginalis fructose-bisphosphate aldolase, putative 0.0663 0.2025 1
Loa Loa (eye worm) latrophilin receptor protein 2 0.0048 0.0103 0.0332
Brugia malayi photoreceptor-specific nuclear receptor 0.0062 0.0148 0.0475
Schistosoma mansoni transcription factor btf3 0.004 0.0079 0.0163
Echinococcus multilocularis lamin 0.0023 0.0027 0.0026
Trichomonas vaginalis ABC transporter, putative 0.0024 0.003 0.0146
Brugia malayi Calcitonin receptor-like protein seb-1 0.0151 0.0426 0.1375
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0035 0.0065 0.0319
Brugia malayi hypothetical protein 0.0064 0.0155 0.05
Brugia malayi SPARC precursor 0.0088 0.0227 0.0733
Schistosoma mansoni photoreceptor-specific nuclear receptor related 0.0062 0.0148 0.0303
Schistosoma mansoni organic anion transporter 0.0128 0.0354 0.073
Loa Loa (eye worm) hypothetical protein 0.0041 0.0083 0.0267
Brugia malayi Pre-SET motif family protein 0.0036 0.0066 0.021
Trypanosoma cruzi mitogen-activated protein kinase 11, putative 0.0116 0.0315 0.0463
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0035 0.0065 0.0319
Plasmodium vivax metacaspase 1, putative 0.002 0.0017 0.0107
Schistosoma mansoni hypothetical protein 0.0195 0.0563 0.116
Echinococcus granulosus smad 0.0017 0.0008 0.0015
Schistosoma mansoni inositol monophosphatase 0.0042 0.0087 0.0177
Mycobacterium ulcerans long-chain-fatty-acid-CoA ligase 0.0027 0.0039 0.0108
Schistosoma mansoni hypothetical protein 0.0928 0.2852 0.5888
Treponema pallidum fructose-bisphosphate aldolase 0.0663 0.2025 1
Schistosoma mansoni retinoic acid receptor RXR 0.0175 0.0502 0.1035
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0135 0.0376 0.0553
Echinococcus granulosus acetylcholinesterase 0.0123 0.0338 0.0695
Trypanosoma brucei mitochondrial DNA polymerase beta-PAK 0.1035 0.3189 0.4696
Trichomonas vaginalis fructose-bisphosphate aldolase, putative 0.0663 0.2025 1
Onchocerca volvulus Bile acid receptor homolog 0.0062 0.0148 0.0461
Leishmania major 4-coumarate:coa ligase-like protein 0.0027 0.0039 0.0056
Trichomonas vaginalis glucosylceramidase, putative 0.0297 0.0881 0.4353
Echinococcus granulosus FTZ F1 alpha 0.0062 0.0148 0.0303
Leishmania major NAD synthase, putative 0.0094 0.0249 0.0366
Trichomonas vaginalis D-aminoacylase, putative 0.0041 0.0083 0.0411
Brugia malayi Nuclear hormone receptor family member nhr-14 0.0062 0.0148 0.0475
Plasmodium falciparum GMP synthase [glutamine-hydrolyzing] 0.0038 0.0072 0.0429
Plasmodium vivax ADP-dependent DNA helicase RecQ, putative 0.0024 0.003 0.0319
Schistosoma mansoni phd/f-box containing protein 0.0036 0.0065 0.0133
Toxoplasma gondii Alpha-galactosidase 0.0017 0.0006 0.005
Loa Loa (eye worm) hypothetical protein 0.0024 0.003 0.0094
Mycobacterium tuberculosis POSSIBLE PARA-NITROBENZYL ESTERASE (FRAGMENT) 0.0021 0.0019 0.0051
Loa Loa (eye worm) hypothetical protein 0.002 0.0018 0.0054
Schistosoma mansoni cpg binding protein 0.0069 0.0169 0.0347
Schistosoma mansoni nuclear hormone receptor 0.0062 0.0148 0.0303
Mycobacterium ulcerans carboxylesterase, LipT 0.0021 0.0019 0.0051
Plasmodium vivax vivapain-2 0.0035 0.0065 0.0884
Loa Loa (eye worm) hypothetical protein 0.0021 0.0019 0.0058
Loa Loa (eye worm) hypothetical protein 0.0062 0.0148 0.0475
Brugia malayi jmjC domain containing protein 0.0036 0.0065 0.0208
Echinococcus multilocularis caspase 3, apoptosis cysteine peptidase 0.002 0.0017 0.0017
Toxoplasma gondii cathepsin CPL 0.0035 0.0065 0.0606
Loa Loa (eye worm) hypothetical protein 0.0128 0.0354 0.1144
Loa Loa (eye worm) hypothetical protein 0.0123 0.0338 0.1089
Echinococcus multilocularis caspase 8 0.002 0.0017 0.0017
Mycobacterium tuberculosis Probable fatty-acid-CoA ligase FadD3 (fatty-acid-CoA synthetase) (fatty-acid-CoA synthase) 0.0019 0.0014 0.0038
Entamoeba histolytica P-glycoprotein-1 0.0024 0.003 0.0093
Plasmodium falciparum ATP-dependent DNA helicase Q1 0.0027 0.0038 0.0187
Plasmodium vivax enoyl-acyl carrier protein reductase 0.0213 0.0619 1
Schistosoma mansoni cathepsin F (C01 family) 0.0035 0.0065 0.0132
Loa Loa (eye worm) intermediate filament protein 0.0023 0.0027 0.0085
Plasmodium vivax multidomain scavenger receptor, putative 0.0064 0.0155 0.2373
Brugia malayi O-Glycosyl hydrolase family 30 protein 0.0297 0.0881 0.2849
Schistosoma mansoni alpha-galactosidase/alpha-n-acetylgalactosaminidase 0.0017 0.0006 0.0011
Plasmodium falciparum DNA-directed RNA polymerase subunit beta, putative 0.0472 0.143 1
Brugia malayi Nuclear hormone receptor family member nhr-41 0.0062 0.0148 0.0475
Brugia malayi Cathepsin L-like precursor 0.0035 0.0065 0.0207
Schistosoma mansoni coup transcription factor 0.0062 0.0148 0.0303
Entamoeba histolytica cysteine protease, putative 0.0035 0.0065 0.0267
Echinococcus multilocularis lysine specific demethylase 5A 0.0133 0.0371 0.037
Onchocerca volvulus 0.0035 0.0065 0.0192
Echinococcus granulosus lipoxygenase domain containing protein 0.0064 0.0155 0.0319
Schistosoma mansoni alpha-galactosidase/alpha-n-acetylgalactosaminidase 0.0079 0.0199 0.041
Echinococcus granulosus cathepsin l1 0.0024 0.0028 0.0056
Brugia malayi ATP-dependent DNA helicase, RecQ family protein 0.0027 0.0038 0.0119
Trichomonas vaginalis ATP-binding cassette transporter, putative 0.0024 0.003 0.0146
Toxoplasma gondii NAC domain-containing protein 0.004 0.0079 0.0746
Entamoeba histolytica transcription factor BTF3, putative 0.004 0.0079 0.034
Mycobacterium ulcerans long-chain fatty-acid CoA ligase 0.0027 0.0039 0.0108
Brugia malayi Smad1 0.0017 0.0008 0.0023
Echinococcus multilocularis smad 0.0017 0.0008 0.0007
Loa Loa (eye worm) hypothetical protein 0.0029 0.0045 0.0144
Toxoplasma gondii histone lysine methyltransferase SET/SUV39 0.0036 0.0066 0.0614
Echinococcus granulosus Ankyrin 0.0017 0.0006 0.0011
Schistosoma mansoni thyroid hormone receptor 0.0062 0.0148 0.0303
Trypanosoma cruzi mitochondrial DNA polymerase beta, putative 0.2188 0.6789 1
Echinococcus multilocularis caspase 0.002 0.0017 0.0017
Echinococcus granulosus netrin receptor unc 5 0.0017 0.0006 0.001
Echinococcus granulosus histone lysine N methyltransferase MLL3 0.0021 0.0021 0.0041
Trichomonas vaginalis ATP-binding cassette transporter, putative 0.0024 0.003 0.0146
Mycobacterium ulcerans enoyl-(acyl carrier protein) reductase 0.0213 0.0619 0.1739
Loa Loa (eye worm) hypothetical protein 0.002 0.0017 0.0054
Echinococcus granulosus mitogen activated protein kinase 0.0116 0.0315 0.0649
Loa Loa (eye worm) hypothetical protein 0.0021 0.0019 0.0058
Trypanosoma brucei mitochondrial DNA polymerase beta 0.2188 0.6789 1
Leishmania major 4-coumarate:coa ligase-like protein 0.0027 0.0039 0.0056
Loa Loa (eye worm) CXXC zinc finger family protein 0.0065 0.0157 0.0507
Trypanosoma cruzi cysteine peptidase, putative 0.0135 0.0376 0.0553
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0018 0.0011 0.0054
Echinococcus multilocularis cadherin EGF LAG seven pass G type receptor 0.0048 0.0103 0.0103
Echinococcus granulosus ATP binding cassette subfamily B MDR:TAP 0.0024 0.003 0.006
Mycobacterium tuberculosis Possible penicillin-binding protein 0.0264 0.078 0.2193
Loa Loa (eye worm) nuclear Hormone Receptor family member 0.0062 0.0148 0.0475
Trichomonas vaginalis Clan CA, family C1, papain-like cysteine peptidase 0.0035 0.0065 0.0319
Trichomonas vaginalis Clan CD, family C14, metacaspase-like cysteine peptidase 0.002 0.0017 0.0086
Echinococcus granulosus caspase 3 apoptosis cysteine peptidase 0.002 0.0017 0.0035
Mycobacterium ulcerans extragenic suppressor protein SuhB 0.0042 0.0087 0.0242
Entamoeba histolytica recQ family helicase, putative 0.003 0.0046 0.0176
Schistosoma mansoni rab6-interacting 0.0064 0.0155 0.0319
Echinococcus granulosus FTZ F1 nuclear receptor protein 0.0062 0.0148 0.0303
Loa Loa (eye worm) hypothetical protein 0.0062 0.0148 0.0475
Echinococcus granulosus geminin 0.0195 0.0563 0.116
Loa Loa (eye worm) MH2 domain-containing protein 0.0253 0.0746 0.241
Echinococcus granulosus cpg binding protein 0.0069 0.0169 0.0347
Schistosoma mansoni hypothetical protein 0.0048 0.0103 0.0212
Onchocerca volvulus 0.0065 0.0157 0.0492
Echinococcus granulosus microtubule associated protein 2 0.1565 0.4843 1
Leishmania major GMP synthase, putative,glutamine amidotransferase, putative 0.0038 0.0072 0.0105
Trichomonas vaginalis ABC transporter, half transporter, putative 0.0024 0.003 0.0146
Trichomonas vaginalis multidrug resistance protein 1, 2, putative 0.0024 0.003 0.0146
Schistosoma mansoni hypothetical protein 0.0048 0.0103 0.0212
Schistosoma mansoni cpg binding protein 0.0065 0.0157 0.0324
Trichomonas vaginalis conserved hypothetical protein 0.004 0.0079 0.0392
Trichomonas vaginalis chromodomain helicase DNA binding protein, putative 0.0015 0.000000000034474 0.00000000017026
Echinococcus granulosus Polycystic kidney disease protein 0.0064 0.0155 0.0319
Brugia malayi Kazal-type serine protease inhibitor domain containing protein 0.0088 0.0227 0.0733
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0035 0.0065 0.0319
Trichomonas vaginalis ABC transporter, putative 0.0024 0.003 0.0146
Onchocerca volvulus Putative organic anion transporter 0.0128 0.0354 0.113
Chlamydia trachomatis ABC transporter ATP binding protein/permease 0.0024 0.003 0.0086
Loa Loa (eye worm) hypothetical protein 0.0033 0.0056 0.018
Trichomonas vaginalis glucosylceramidase, putative 0.0297 0.0881 0.4353
Entamoeba histolytica P-glycoprotein-2 0.0024 0.003 0.0093
Entamoeba histolytica cysteine proteinase, putative 0.0024 0.0028 0.0085
Schistosoma mansoni hypothetical protein 0.0195 0.0563 0.116
Loa Loa (eye worm) intermediate filament tail domain-containing protein 0.0023 0.0027 0.0085
Echinococcus multilocularis multidrug resistance protein 1 0.0024 0.003 0.0029
Loa Loa (eye worm) hypothetical protein 0.0047 0.0102 0.0327
Schistosoma mansoni retinoid-x-receptor (RXR) 0.0033 0.0056 0.0115
Onchocerca volvulus 0.0062 0.0148 0.0461
Mycobacterium leprae DNA-DIRECTED RNA POLYMERASE (BETA CHAIN) RPOB (TRANSCRIPTASE BETA CHAIN) (RNA POLYMERASE BETA SUBUNIT) 0.0472 0.143 1
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0135 0.0376 0.0553
Loa Loa (eye worm) jmjC domain-containing protein 0.0137 0.0382 0.1234
Brugia malayi hypothetical protein 0.0047 0.0102 0.0327
Echinococcus multilocularis cathepsin l cysteine peptidase 0.0035 0.0065 0.0064
Trypanosoma cruzi cysteine peptidase (N-terminal), putative 0.0018 0.0011 0.0015
Trichomonas vaginalis D-aminoacylase, putative 0.0041 0.0083 0.0411
Trypanosoma cruzi cytochrome P450, putative 0.0034 0.0059 0.0085
Echinococcus granulosus Transcription factor JmjC domain containing protein 0.0133 0.0371 0.0764
Brugia malayi jmjC domain containing protein 0.0133 0.0371 0.1196
Onchocerca volvulus 0.0047 0.0102 0.0312
Toxoplasma gondii transporter, major facilitator family protein 0.0128 0.0354 0.3351
Loa Loa (eye worm) ICD-1 protein 0.004 0.0079 0.0255
Trichomonas vaginalis multidrug resistance protein 1, 2, putative 0.0024 0.003 0.0146
Leishmania major hypothetical protein, conserved 0.0036 0.0065 0.0095
Echinococcus multilocularis ATP dependent DNA helicase Q5 0.0027 0.0038 0.0037
Trypanosoma brucei transcription factor BTF3, putative 0.004 0.0079 0.0116
Mycobacterium tuberculosis Inositol-1-monophosphatase SuhB 0.0038 0.0073 0.0202
Leishmania major 4-coumarate:coa ligase-like protein 0.0027 0.0039 0.0056
Toxoplasma gondii ATP-dependent DNA helicase, RecQ family protein 0.0027 0.0038 0.0348
Echinococcus multilocularis TGF beta signal transducer SmadC 0.0017 0.0008 0.0007
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0018 0.0011 0.0054
Toxoplasma gondii ICE family protease (caspase) p20 domain-containing protein 0.002 0.0017 0.0158
Trichomonas vaginalis esterase, putative 0.0041 0.0083 0.0411
Loa Loa (eye worm) hypothetical protein 0.0017 0.0006 0.0016
Brugia malayi intermediate filament protein 0.0023 0.0027 0.0085
Trichomonas vaginalis chromodomain helicase DNA binding protein, putative 0.0015 0.000000000034474 0.00000000017026
Mycobacterium ulcerans lipase LipD 0.0041 0.0083 0.0232
Trichomonas vaginalis Clan CA, family C1, papain-like cysteine peptidase 0.0035 0.0065 0.0319
Brugia malayi Carboxylesterase family protein 0.0021 0.0019 0.0058
Echinococcus multilocularis ankyrin repeat and death domain containing protein 0.0017 0.0006 0.0005
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0035 0.0065 0.0319
Trypanosoma brucei PAB1-binding protein , putative 0.0029 0.0044 0.0064
Entamoeba histolytica hypothetical protein 0.0041 0.0083 0.0358
Trypanosoma cruzi mitogen-activated protein kinase 11, putative 0.0116 0.0315 0.0463
Schistosoma mansoni multidrug resistance protein 0.0024 0.003 0.006
Onchocerca volvulus 0.0035 0.0065 0.0192
Echinococcus multilocularis acetylcholinesterase 0.0123 0.0338 0.0337
Echinococcus granulosus neuroligin 0.0021 0.0019 0.0037
Toxoplasma gondii Kazal-type serine protease inhibitor domain-containing protein 0.0088 0.0227 0.2147
Mycobacterium leprae PROBABLE FATTY-ACID-CoA LIGASE FADD2 (FATTY-ACID-CoA SYNTHETASE) (FATTY-ACID-CoA SYNTHASE) 0.0027 0.0039 0.0268
Leishmania major ATP-binding cassette protein subfamily B, member 2, putative 0.0024 0.003 0.0043
Giardia lamblia Kinase, CMGC MAPK 0.0116 0.0315 0.1396
Schistosoma mansoni DNA helicase recq1 0.0027 0.0038 0.0076
Echinococcus multilocularis Nuclear hormone receptor family member nhr 41 0.0062 0.0148 0.0147
Schistosoma mansoni intermediate filament proteins 0.0023 0.0027 0.0054
Echinococcus granulosus muscleblind protein 0.0339 0.1012 0.2089
Echinococcus multilocularis Polycystic kidney disease protein 0.0064 0.0155 0.0154
Echinococcus multilocularis expressed protein 0.0088 0.0227 0.0227
Trichomonas vaginalis Clan CD, family C14, metacaspase-like cysteine peptidase 0.002 0.0017 0.0086
Entamoeba histolytica hypothetical protein 0.0041 0.0083 0.0358
Loa Loa (eye worm) MH2 domain-containing protein 0.0017 0.0008 0.0023
Trypanosoma brucei GMP synthase [glutamine-hydrolysing] 0.0038 0.0072 0.0105
Wolbachia endosymbiont of Brugia malayi DNA-directed RNA polymerase subunit beta/beta' 0.0472 0.143 1
Echinococcus multilocularis GPCR, family 2 0.0048 0.0103 0.0103
Loa Loa (eye worm) TAR-binding protein 0.0073 0.0181 0.0584
Trichomonas vaginalis penicillin-binding protein, putative 0.0041 0.0083 0.0411
Entamoeba histolytica hypothetical protein 0.0041 0.0083 0.0358
Trypanosoma cruzi JmjC domain, hydroxylase, putative 0.0036 0.0065 0.0095
Schistosoma mansoni family S9 non-peptidase homologue (S09 family) 0.0021 0.0019 0.0037
Trypanosoma brucei metacaspase 5, putative 0.002 0.0017 0.0025
Echinococcus multilocularis Nuclear hormone receptor HR96 0.0029 0.0045 0.0045
Toxoplasma gondii Kazal-type serine protease inhibitor domain-containing protein 0.0088 0.0227 0.2147
Trypanosoma brucei mitogen activated protein kinase 4, putative 0.0116 0.0315 0.0463
Loa Loa (eye worm) hypothetical protein 0.0029 0.0045 0.0144
Brugia malayi ecdysone receptor 0.0029 0.0045 0.0144
Mycobacterium ulcerans cytochrome P450 185A4 Cyp185A4 0.0034 0.0059 0.0163
Brugia malayi Nuclear hormone receptor family member nhr-3 0.0062 0.0148 0.0475
Trypanosoma cruzi PAB1-binding protein , putative 0.0029 0.0044 0.0064
Trichomonas vaginalis Clan CA, family C1, papain-like cysteine peptidase 0.0035 0.0065 0.0319
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0035 0.0065 0.0319
Loa Loa (eye worm) hypothetical protein 0.0041 0.0083 0.0267
Plasmodium vivax acyl-CoA synthetase, putative 0.002 0.0018 0.0108
Trypanosoma cruzi cysteine proteinase, putative 0.0018 0.0011 0.0015
Trichomonas vaginalis penicillin-binding protein, putative 0.0041 0.0083 0.0411
Leishmania major cytochrome p450-like protein 0.0034 0.0059 0.0085
Brugia malayi jmjC domain containing protein 0.0137 0.0382 0.1234
Loa Loa (eye worm) hypothetical protein 0.0029 0.0045 0.0144
Echinococcus granulosus GPCR family 2 0.0048 0.0103 0.0212
Plasmodium falciparum multidrug resistance protein 1 0.0024 0.003 0.0132
Brugia malayi Iron-sulfur cluster assembly accessory protein 0.0055 0.0127 0.0409
Leishmania major myo-inositol-1(or 4)-monophosphatase 1, putative 0.0042 0.0087 0.0126
Loa Loa (eye worm) carboxylesterase 0.0021 0.0019 0.0058
Mycobacterium tuberculosis Conserved hypothetical protein 0.1152 0.3554 1
Plasmodium falciparum ataxin-2 like protein, putative 0.0029 0.0044 0.0236
Onchocerca volvulus 0.0128 0.0354 0.113
Trichomonas vaginalis CMGC family protein kinase 0.0116 0.0315 0.1555
Brugia malayi orphan nuclear receptor NR2E1 0.0029 0.0045 0.0144
Trichomonas vaginalis taga, putative 0.0024 0.003 0.0146
Loa Loa (eye worm) hypothetical protein 0.0024 0.0029 0.0091
Toxoplasma gondii ICE family protease (caspase) p20 domain-containing protein 0.002 0.0017 0.0158
Echinococcus multilocularis pol protein 0.3216 1 1
Echinococcus multilocularis nuclear factor of activated T cells 5 0.0085 0.0218 0.0218
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0135 0.0376 0.0553
Loa Loa (eye worm) hypothetical protein 0.0041 0.0083 0.0267
Toxoplasma gondii ICE family protease (caspase) p20 domain-containing protein 0.002 0.0017 0.0158
Schistosoma mansoni hypothetical protein 0.0055 0.0127 0.0261
Mycobacterium tuberculosis Probable esterase/lipase LipP 0.0041 0.0083 0.0232
Loa Loa (eye worm) hypothetical protein 0.1005 0.3092 1
Echinococcus granulosus cadherin EGF LAG seven pass G type receptor 0.0048 0.0103 0.0212
Mycobacterium tuberculosis DNA-directed RNA polymerase (beta chain) RpoB (transcriptase beta chain) (RNA polymerase beta subunit) 0.0472 0.143 0.4021
Schistosoma mansoni caspase-3 (C14 family) 0.002 0.0017 0.0035
Trypanosoma cruzi cysteine protease, putative 0.0018 0.0011 0.0015
Echinococcus multilocularis ecdysone induced protein 78C 0.0062 0.0148 0.0147
Schistosoma mansoni microtubule-associated protein tau 0.1565 0.4843 1
Brugia malayi Nuclear hormone receptor-like 1 0.0062 0.0148 0.0475
Loa Loa (eye worm) acetylcholinesterase 1 0.0123 0.0338 0.1089
Schistosoma mansoni lipoxygenase 0.0137 0.038 0.0784
Echinococcus multilocularis acetylcholinesterase 0.0123 0.0338 0.0337
Schistosoma mansoni transcription factor LCR-F1 0.0041 0.0083 0.017
Mycobacterium ulcerans fatty-acid-CoA ligase 0.002 0.0018 0.0047
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0135 0.0376 0.0553
Mycobacterium ulcerans beta-lactamase 0.0041 0.0083 0.0232
Trichomonas vaginalis abcb9, putative 0.0024 0.003 0.0146
Trichomonas vaginalis hypothetical protein 0.0213 0.0619 0.3055
Brugia malayi secreted modular calcium-binding protein 1 0.0088 0.0227 0.0733
Entamoeba histolytica acyl-CoA synthetase, putative 0.0027 0.0039 0.0139
Trichomonas vaginalis glucosylceramidase, putative 0.0205 0.0595 0.294
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0035 0.0065 0.0319
Brugia malayi Carboxylesterase family protein 0.0021 0.0019 0.0058
Echinococcus granulosus cathepsin l1 0.0035 0.0065 0.0132
Schistosoma mansoni polycystin 1-related 0.0064 0.0155 0.0319
Brugia malayi Nuclear hormone receptor E75 0.0029 0.0045 0.0144
Trichomonas vaginalis chromodomain-helicase-DNA-binding protein, putative 0.0015 0.000000000034474 0.00000000017026
Echinococcus multilocularis pol protein 0.3216 1 1
Chlamydia trachomatis DNA-directed RNA polymerase subunit beta 0.0472 0.143 1
Brugia malayi nuclear hormone receptor family member nhr-6 0.0029 0.0045 0.0144
Trichomonas vaginalis nh(3)-dependent NAD(+) synthetase, putative 0.0094 0.0249 0.1229
Loa Loa (eye worm) ATP-binding cassette sub-family B member 2 0.0024 0.003 0.0094
Echinococcus multilocularis nuclear receptor 2DBD gamma 0.0029 0.0045 0.0045
Trichomonas vaginalis conserved hypothetical protein 0.002 0.0017 0.0086
Loa Loa (eye worm) MH1 domain-containing protein 0.0017 0.0008 0.0023
Echinococcus granulosus caspase 0.002 0.0017 0.0035
Echinococcus granulosus acetylcholinesterase 0.0123 0.0338 0.0695
Brugia malayi MH1 domain containing protein 0.0017 0.0008 0.0023
Leishmania major hypothetical protein, conserved 0.0041 0.0083 0.0122
Brugia malayi Nuclear hormone receptor-like 1 0.0033 0.0056 0.018
Loa Loa (eye worm) hypothetical protein 0.0021 0.0019 0.0058
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0135 0.0376 0.0553
Trichomonas vaginalis ATP-binding cassette transporter, putative 0.0024 0.003 0.0146
Mycobacterium tuberculosis Probable conserved lipoprotein 0.0041 0.0083 0.0232
Loa Loa (eye worm) DR-78 0.0029 0.0045 0.0144
Brugia malayi Latrophilin receptor protein 2 0.0048 0.0103 0.0332
Plasmodium vivax basic transcription factor 3b, putative 0.004 0.0079 0.1128
Trypanosoma cruzi cysteine peptidase, clan CA, family C1, cathepsin L-like, putative 0.0123 0.0339 0.0499
Loa Loa (eye worm) hypothetical protein 0.0021 0.0019 0.0058
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0035 0.0065 0.0319
Loa Loa (eye worm) hypothetical protein 0.0339 0.1012 0.3272
Schistosoma mansoni histone-lysine n-methyltransferase setb1 0.0036 0.0066 0.0134
Echinococcus multilocularis GMP synthase (glutamine hydrolyzing) 0.0038 0.0072 0.0071
Trypanosoma brucei ATP-dependent DEAD/H DNA helicase recQ, putative 0.003 0.0046 0.0067
Brugia malayi Nuclear hormone receptor family member nhr-49 0.0062 0.0148 0.0475
Onchocerca volvulus 0.0021 0.0019 0.0043
Echinococcus multilocularis Protein lozenge 0.0126 0.0348 0.0347
Echinococcus multilocularis tar DNA binding protein 0.0073 0.0181 0.0181
Wolbachia endosymbiont of Brugia malayi enoyl-ACP reductase 0.0213 0.0619 0.3961
Loa Loa (eye worm) transcription factor SMAD2 0.0253 0.0746 0.241
Brugia malayi Cathepsin L-like precursor 0.0035 0.0065 0.0207
Mycobacterium ulcerans hypothetical protein 0.0027 0.0039 0.0108
Echinococcus granulosus 5'partial|ATP binding cassette sub family B 0.0024 0.0029 0.0058
Echinococcus multilocularis RUN 0.0064 0.0155 0.0154
Trichomonas vaginalis fructose-bisphosphate aldolase, putative 0.0663 0.2025 1
Plasmodium falciparum basic transcription factor 3b, putative 0.004 0.0079 0.0483
Brugia malayi Papain family cysteine protease containing protein 0.0035 0.0065 0.0207
Echinococcus multilocularis COUP TF:Svp nuclear hormone receptor 0.0062 0.0148 0.0147
Loa Loa (eye worm) nuclear receptor NHR-67 0.0029 0.0045 0.0144
Brugia malayi Doublecortin family protein 0.0064 0.0155 0.05
Echinococcus granulosus mothers against decapentaplegic 5 0.0017 0.0008 0.0015
Toxoplasma gondii histone lysine demethylase JMJC1/KDM5D/JARID1D 0.0036 0.0065 0.0609
Mycobacterium tuberculosis POSSIBLE PARA-NITROBENZYL ESTERASE (FRAGMENT) 0.0021 0.0019 0.0051
Brugia malayi Nuclear hormone receptor family member nhr-31 0.0062 0.0148 0.0475
Schistosoma mansoni steroid hormone receptor ad4bp 0.0062 0.0148 0.0303
Echinococcus multilocularis survival motor neuron protein 1 0.0272 0.0803 0.0803
Brugia malayi Bloom's syndrome protein homolog 0.004 0.008 0.0257
Loa Loa (eye worm) histone methyltransferase 0.0021 0.0021 0.0065
Schistosoma mansoni smad1 5 8 and 0.0017 0.0008 0.0015
Trichomonas vaginalis ATP-binding cassette transporter, putative 0.0024 0.003 0.0146
Echinococcus granulosus JmjC domain containing protein 4 0.0036 0.0065 0.0133
Brugia malayi nuclear receptor NHR-67 0.0029 0.0045 0.0144
Plasmodium vivax SET domain protein, putative 0.0036 0.0066 0.0899
Loa Loa (eye worm) hypothetical protein 0.0027 0.0039 0.0124
Mycobacterium tuberculosis Conserved protein 0.0041 0.0083 0.0232
Loa Loa (eye worm) steroid hormone receptor 0.0062 0.0148 0.0475
Entamoeba histolytica P-glycoprotein 5, putative 0.0024 0.003 0.0093
Schistosoma mansoni nuclear receptor 2DBD-gamma 0.0062 0.0148 0.0303
Schistosoma mansoni gliotactin 0.0021 0.0019 0.0037
Trypanosoma brucei JmjC domain, hydroxylase, putative 0.0036 0.0065 0.0095
Trypanosoma brucei hypothetical protein, conserved 0.0041 0.0083 0.0122
Onchocerca volvulus Nuclear receptor subfamily 6 group A member 1 homolog 0.0029 0.0045 0.0129
Toxoplasma gondii protease inhibitor PI2 0.0088 0.0227 0.2147
Toxoplasma gondii enoyl-acyl carrier reductase ENR 0.0213 0.0619 0.5853
Loa Loa (eye worm) hypothetical protein 0.0029 0.0045 0.0144
Trypanosoma cruzi metacaspase, putative 0.002 0.0017 0.0025
Schistosoma mansoni BC026374 protein (S09 family) 0.0021 0.0019 0.0037
Trichomonas vaginalis ATP-binding cassette transporter, putative 0.0024 0.003 0.0146
Brugia malayi jmjC domain containing protein 0.0036 0.0065 0.0208
Leishmania major mitogen activated protein kinase 4, putative;with=GeneDB:LmxM19.1440 0.0116 0.0315 0.0463
Trichomonas vaginalis conserved hypothetical protein 0.002 0.0017 0.0086
Echinococcus multilocularis histone lysine N methyltransferase MLL3 0.0017 0.0008 0.0008
Plasmodium falciparum LCCL domain-containing protein 0.0064 0.0155 0.1016
Schistosoma mansoni neuroligin 3 (S09 family) 0.0021 0.0019 0.0037
Loa Loa (eye worm) hypothetical protein 0.0106 0.0285 0.0921
Trichomonas vaginalis Clan CD, family C14, metacaspase-like cysteine peptidase 0.002 0.0017 0.0086
Loa Loa (eye worm) nuclear hormone receptor family member nhr-1 0.0062 0.0148 0.0475
Trypanosoma brucei metacaspase MCA2 0.002 0.0017 0.0025
Echinococcus multilocularis netrin receptor unc 5 0.0017 0.0006 0.0005
Echinococcus multilocularis neuroligin 0.0021 0.0019 0.0018
Schistosoma mansoni subfamily C14A unassigned peptidase (C14 family) 0.002 0.0017 0.0035
Trichomonas vaginalis CMGC family protein kinase 0.0116 0.0315 0.1555
Onchocerca volvulus 0.0023 0.0027 0.0069
Mycobacterium ulcerans long-chain-fatty-acid--CoA ligase 0.0027 0.0039 0.0108
Brugia malayi Kazal-type serine protease inhibitor domain containing protein 0.0088 0.0227 0.0733
Mycobacterium leprae NADH-DEPENDENT ENOYL-[ACYL-CARRIER-PROTEIN] REDUCTASE INHA (NADH-DEPENDENT ENOYL-ACP REDUCTASE) 0.0213 0.0619 0.4324
Echinococcus multilocularis cysteine protease 0.0035 0.0065 0.0064
Loa Loa (eye worm) nuclear hormone receptor 0.0029 0.0045 0.0144
Brugia malayi latrophilin 2 splice variant baaae 0.0103 0.0277 0.0892
Brugia malayi Pre-SET motif family protein 0.0241 0.0706 0.2281
Echinococcus granulosus multidrug resistance protein 1 0.0024 0.003 0.006
Loa Loa (eye worm) hypothetical protein 0.002 0.0018 0.0054
Onchocerca volvulus 0.0035 0.0065 0.0192
Loa Loa (eye worm) hypothetical protein 0.0339 0.1012 0.3272
Trypanosoma cruzi mitochondrial DNA polymerase beta-PAK, putative 0.1035 0.3189 0.4696
Trichomonas vaginalis inositol monophosphatase, putative 0.0042 0.0087 0.0427
Schistosoma mansoni zinc finger protein 0.0029 0.0045 0.0092
Mycobacterium ulcerans acyl-CoA synthetase 0.0027 0.0039 0.0108
Trypanosoma brucei DNA polymerase beta thumb, putative 0.0308 0.0915 0.1347
Loa Loa (eye worm) RNA recognition domain-containing protein domain-containing protein 0.0073 0.0181 0.0584
Echinococcus granulosus lipoxygenase domain containing protein 0.0064 0.0155 0.0319
Plasmodium falciparum glutamine-dependent NAD(+) synthetase, putative 0.0094 0.0249 0.1677
Schistosoma mansoni caspase-7 (C14 family) 0.0068 0.0165 0.034
Echinococcus multilocularis dnaJ subfamily B 0.0928 0.2852 0.2852
Brugia malayi hypothetical protein 0.0019 0.0012 0.0038
Loa Loa (eye worm) hypothetical protein 0.0033 0.0056 0.018
Onchocerca volvulus 0.0055 0.0127 0.0394
Loa Loa (eye worm) hypothetical protein 0.1005 0.3092 1
Trypanosoma cruzi metacaspase, putative 0.002 0.0017 0.0025
Schistosoma mansoni RAR-like nuclear receptor 0.0062 0.0148 0.0303
Entamoeba histolytica NAD synthetase, putative 0.0094 0.0249 0.1181
Echinococcus multilocularis multidrug resistance protein 1 0.0017 0.0007 0.0006
Echinococcus multilocularis musashi 0.0023 0.0027 0.0026
Schistosoma mansoni family S9 non-peptidase homologue (S09 family) 0.0021 0.0019 0.0037
Loa Loa (eye worm) papain family cysteine protease containing protein 0.0035 0.0065 0.0207
Loa Loa (eye worm) pre-SET domain-containing protein family protein 0.0241 0.0706 0.2281
Schistosoma mansoni tar DNA-binding protein 0.0073 0.0181 0.0373
Toxoplasma gondii histone lysine methyltransferase SET1 0.0125 0.0343 0.3246
Loa Loa (eye worm) hypothetical protein 0.0106 0.0285 0.0921
Echinococcus multilocularis Basic leucine zipper (bZIP) transcription 0.0041 0.0083 0.0082
Schistosoma mansoni smdr2 0.0024 0.003 0.006
Trichomonas vaginalis chromodomain helicase DNA binding protein, putative 0.0015 0.000000000034474 0.00000000017026
Brugia malayi prostaglandin transporter 0.0128 0.0354 0.1144
Brugia malayi Nuclear hormone receptor family member nhr-25 0.0062 0.0148 0.0475
Trichomonas vaginalis lipid A export ATP-binding/permease protein msba, putative 0.0024 0.003 0.0146
Loa Loa (eye worm) inositol-1 0.0042 0.0087 0.0278
Loa Loa (eye worm) immunoglobulin I-set domain-containing protein 0.0017 0.0006 0.0016
Brugia malayi hypothetical protein 0.0021 0.0019 0.0058
Echinococcus granulosus nuclear factor of activated T cells 5 0.0085 0.0218 0.0449
Trichomonas vaginalis lipid A export ATP-binding/permease protein msba, putative 0.0024 0.003 0.0146
Mycobacterium tuberculosis Conserved protein 0.0041 0.0083 0.0232
Schistosoma mansoni family S12 unassigned peptidase (S12 family) 0.0041 0.0083 0.017
Brugia malayi Cytochrome P450 family protein 0.0034 0.0059 0.0187
Echinococcus multilocularis Nuclear hormone receptor HR96 0.0029 0.0045 0.0045
Trichomonas vaginalis ATP-binding cassette transporter, putative 0.0017 0.0007 0.0033
Loa Loa (eye worm) hypothetical protein 0.002 0.0018 0.0054
Trypanosoma cruzi metacaspase 5, putative 0.002 0.0017 0.0025
Onchocerca volvulus Cell death protein 3 homolog 0.0068 0.0165 0.0518
Echinococcus multilocularis cathepsin L cysteine protease 0.0035 0.0065 0.0064
Echinococcus multilocularis para nitrobenzyl esterase 0.0021 0.0019 0.0018
Plasmodium vivax JmjC domain containing protein 0.0036 0.0065 0.089
Loa Loa (eye worm) GTP-binding regulatory protein Gs alpha-S chain 0.0097 0.0257 0.0827
Schistosoma mansoni alpha-galactosidase/alpha-n-acetylgalactosaminidase 0.0118 0.0322 0.0663
Brugia malayi Ligand-binding domain of nuclear hormone receptor family protein 0.0062 0.0148 0.0475
Brugia malayi Cell death protein 3 precursor 0.0068 0.0165 0.0533
Loa Loa (eye worm) hypothetical protein 0.0027 0.0039 0.0124
Trichomonas vaginalis multidrug resistance protein 1, 2, putative 0.0024 0.003 0.0146
Onchocerca volvulus 0.0021 0.0019 0.0043
Schistosoma mansoni lipoxygenase 0.0252 0.0743 0.1532
Loa Loa (eye worm) hypothetical protein 0.0017 0.0006 0.0017
Schistosoma mansoni cathepsin F (C01 family) 0.0024 0.0028 0.0056
Brugia malayi nuclear receptor RXR 0.0033 0.0056 0.018
Loa Loa (eye worm) nuclear hormone receptor family member nhr-31 0.0062 0.0148 0.0475
Echinococcus granulosus arachidonate 5 lipoxygenase 0.0252 0.0743 0.1532
Echinococcus granulosus RUN 0.0064 0.0155 0.0319
Trypanosoma cruzi NAD+ synthase, putative 0.0094 0.0249 0.0366
Schistosoma mansoni ubiquitously transcribed sex (X/Y) chromosome tetratricopeptide repeat protein-related 0.0036 0.0065 0.0133
Trypanosoma cruzi mitogen activated protein kinase 4, putative 0.0116 0.0315 0.0463
Trichomonas vaginalis lipid A export ATP-binding/permease protein msba, putative 0.0024 0.003 0.0146
Trichomonas vaginalis glucosylceramidase, putative 0.0297 0.0881 0.4353
Echinococcus multilocularis cathepsin L 0.0018 0.0011 0.001
Onchocerca volvulus 0.0128 0.0354 0.113
Brugia malayi sodium-independent organic anion transporter family protein 0.0128 0.0354 0.1144
Loa Loa (eye worm) hypothetical protein 0.0036 0.0066 0.021
Schistosoma mansoni nuclear hormone receptor superfamily protein-related 0.0029 0.0045 0.0092
Trichomonas vaginalis fructose-bisphosphate aldolase, putative 0.0663 0.2025 1
Echinococcus multilocularis nuclear receptor 2DBD gamma 0.0062 0.0148 0.0147
Echinococcus granulosus BC026374 protein S09 family 0.0021 0.0019 0.0037
Brugia malayi Cytochrome P450 family protein 0.0034 0.0059 0.0187
Brugia malayi hypothetical protein 0.0106 0.0285 0.0921
Schistosoma mansoni retinoid-x-receptor (RXR) 0.0062 0.0148 0.0303
Brugia malayi hypothetical protein 0.0041 0.0083 0.0267
Trichomonas vaginalis CMGC family protein kinase 0.0116 0.0315 0.1555
Entamoeba histolytica cysteine proteinase, putative 0.0035 0.0065 0.0267
Schistosoma mansoni hypothetical protein 0.0111 0.0301 0.0619
Mycobacterium ulcerans fatty-acid-CoA ligase 0.0027 0.0039 0.0108
Mycobacterium tuberculosis Conserved protein 0.0041 0.0083 0.0232
Loa Loa (eye worm) hypothetical protein 0.0036 0.0065 0.0208
Echinococcus multilocularis pol protein 0.3216 1 1
Echinococcus granulosus nuclear receptor subfamily 4 group A 0.0029 0.0045 0.0092
Schistosoma mansoni alpha-galactosidase/alpha-n-acetylgalactosaminidase 0.0118 0.0322 0.0663
Brugia malayi hypothetical protein 0.1005 0.3092 1
Loa Loa (eye worm) hypothetical protein 0.0048 0.0103 0.0332
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0135 0.0376 0.0553
Echinococcus multilocularis lipoxygenase domain containing protein 0.0064 0.0155 0.0154
Trypanosoma cruzi hypothetical protein, conserved 0.0041 0.0083 0.0122
Loa Loa (eye worm) hypothetical protein 0.0021 0.0019 0.0058
Echinococcus granulosus lamin 0.0023 0.0027 0.0054
Schistosoma mansoni hypothetical protein 0.0048 0.0103 0.0212
Echinococcus granulosus Nuclear hormone receptor family member nhr 41 0.0062 0.0148 0.0303
Onchocerca volvulus 0.0064 0.0155 0.0485
Mycobacterium ulcerans glutaminase 0.0314 0.0936 0.2631
Trypanosoma cruzi cruzipain precursor, putative 0.0135 0.0376 0.0553
Echinococcus multilocularis nuclear receptor subfamily 4 group A 0.0029 0.0045 0.0045
Onchocerca volvulus Cathepsin L homolog 0.0035 0.0065 0.0192
Leishmania major p-glycoprotein 0.0024 0.003 0.0043
Trichomonas vaginalis abcb9, putative 0.0024 0.003 0.0146
Schistosoma mansoni nuclear receptor 0.0029 0.0045 0.0092
Echinococcus granulosus ATP binding cassette subfamily B MDR:TAP 0.0024 0.003 0.006
Schistosoma mansoni ankyrin 23/unc44 0.0017 0.0006 0.001
Schistosoma mansoni SmCL2-like peptidase (C01 family) 0.0018 0.0011 0.0021
Schistosoma mansoni alpha-galactosidase/alpha-n-acetylgalactosaminidase 0.0118 0.0322 0.0663
Trichomonas vaginalis D-aminoacylase, putative 0.0041 0.0083 0.0411
Echinococcus granulosus cathepsin L cysteine proteinase 0.0035 0.0065 0.0132
Brugia malayi beta-lactamase 0.0041 0.0083 0.0267
Brugia malayi Kazal-type serine protease inhibitor domain containing protein 0.0088 0.0227 0.0733
Echinococcus multilocularis carboxylesterase 5A 0.0123 0.0338 0.0337
Entamoeba histolytica hypothetical protein 0.0041 0.0083 0.0358
Echinococcus multilocularis ATP binding cassette subfamily B (MDR:TAP) 0.0024 0.003 0.0029
Mycobacterium ulcerans hypothetical protein 0.0041 0.0083 0.0232
Echinococcus granulosus ATP dependent DNA helicase Q1 0.0027 0.0038 0.0076
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0035 0.0065 0.0319
Brugia malayi beta-lactamase family protein 0.0041 0.0083 0.0267
Brugia malayi RNA recognition motif domain containing protein 0.0073 0.0181 0.0584
Brugia malayi Cathepsin L-like precursor 0.0035 0.0065 0.0207
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0135 0.0376 0.0553
Schistosoma mansoni retinoblastoma-binding protein 4 (rbbp4) 0.0017 0.0006 0.0011
Brugia malayi TAR-binding protein 0.0073 0.0181 0.0584
Trichomonas vaginalis chromodomain-helicase-DNA-binding protein, putative 0.0015 0.000000000034474 0.00000000017026
Echinococcus multilocularis mixed lineage leukemia protein mll 0.0017 0.0008 0.0008
Onchocerca volvulus Putative organic anion transporter 0.0128 0.0354 0.113
Brugia malayi RNA binding protein 0.0073 0.0181 0.0584
Trypanosoma cruzi myo-inositol-1(or 4)-monophosphatase 1, putative 0.0042 0.0087 0.0126
Brugia malayi Immunoglobulin I-set domain containing protein 0.0017 0.0006 0.0016
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0024 0.0028 0.0139
Trichomonas vaginalis Clan CD, family C14, metacaspase-like cysteine peptidase 0.002 0.0017 0.0086
Trypanosoma brucei cytochrome P450, putative 0.0034 0.0059 0.0085
Mycobacterium ulcerans acyl-CoA synthetase 0.0027 0.0039 0.0108
Leishmania major cathepsin L-like protease 0.0035 0.0065 0.0094
Echinococcus granulosus multidrug resistance protein 1 0.0017 0.0007 0.0012
Loa Loa (eye worm) cytochrome P450 family protein 0.0034 0.0059 0.0187
Loa Loa (eye worm) hypothetical protein 0.0035 0.0065 0.0207
Mycobacterium leprae Probable lipase LipE 0.0041 0.0083 0.0577
Brugia malayi jmjC domain containing protein 0.0036 0.0065 0.0208
Entamoeba histolytica hypothetical protein 0.004 0.0079 0.034
Echinococcus multilocularis microtubule associated protein 2 0.1565 0.4843 0.4843
Echinococcus granulosus multidrug resistance protein 1 0.0017 0.0007 0.0012
Trichomonas vaginalis fructose-bisphosphate aldolase, putative 0.0663 0.2025 1
Brugia malayi Kazal-type serine protease inhibitor domain containing protein 0.0088 0.0227 0.0733
Trichomonas vaginalis abcb9, putative 0.0024 0.003 0.0146
Schistosoma mansoni lamin 0.0023 0.0027 0.0054
Brugia malayi AMP-binding enzyme family protein 0.0027 0.0039 0.0124
Schistosoma mansoni tar DNA-binding protein 0.0073 0.0181 0.0373
Loa Loa (eye worm) hypothetical protein 0.0029 0.0045 0.0144
Trichomonas vaginalis ABC transporter, putative 0.0024 0.003 0.0146
Echinococcus multilocularis retinoic acid receptor rxr beta a retinoic acid receptor rxr alpha a retinoic acid receptor rxr alpha 0.0143 0.0399 0.0399
Echinococcus granulosus nuclear receptor 2DBD gamma 0.0062 0.0148 0.0303
Schistosoma mansoni nuclear hormone receptor 0.0029 0.0045 0.0092
Loa Loa (eye worm) hypothetical protein 0.0062 0.0148 0.0475
Onchocerca volvulus 0.0035 0.0065 0.0192
Loa Loa (eye worm) hypothetical protein 0.0123 0.0338 0.1089
Echinococcus multilocularis histone lysine methyltransferase setb histone lysine methyltransferase eggless 0.0036 0.0066 0.0065
Loa Loa (eye worm) hypothetical protein 0.0079 0.0199 0.0642
Entamoeba histolytica P-glycoprotein-2, putative 0.0024 0.003 0.0093
Leishmania major cathepsin L-like protease 0.0135 0.0376 0.0553
Brugia malayi glutaminase DH11.1 0.0314 0.0936 0.3024
Echinococcus granulosus death domain containing protein 0.0017 0.0006 0.001
Brugia malayi GMP synthase 0.0038 0.0072 0.023
Echinococcus multilocularis lysine specific demethylase 6a 0.0036 0.0065 0.0064
Trichomonas vaginalis chromodomain helicase DNA binding protein, putative 0.0015 0.000000000034474 0.00000000017026
Schistosoma mansoni lamin 0.0023 0.0027 0.0054
Trypanosoma cruzi MFS transporter, putative 0.0128 0.0354 0.0521
Loa Loa (eye worm) nuclear hormone receptor family member nhr-41 0.0062 0.0148 0.0475
Entamoeba histolytica myo-inositol monophosphatase, putative 0.0042 0.0087 0.0375
Onchocerca volvulus 0.0021 0.0019 0.0043
Echinococcus granulosus apoptotic protease activating factor 1 0.0047 0.0102 0.0209
Brugia malayi Papain family cysteine protease containing protein 0.0018 0.0011 0.0033
Echinococcus multilocularis arachidonate 5 lipoxygenase 0.0252 0.0743 0.0742
Trichomonas vaginalis glucosylceramidase, putative 0.0195 0.0562 0.2778
Trichomonas vaginalis conserved hypothetical protein 0.004 0.0079 0.0392
Trichomonas vaginalis conserved hypothetical protein 0.004 0.0079 0.0392
Schistosoma mansoni nuclear hormone receptor nor-1/nor-2 0.0062 0.0148 0.0303
Entamoeba histolytica acyl-coA synthetase, putative 0.0027 0.0039 0.0139
Brugia malayi hypothetical protein 0.0064 0.0155 0.05
Trichomonas vaginalis glucosylceramidase, putative 0.0297 0.0881 0.4353
Echinococcus multilocularis muscleblind protein 0.0339 0.1012 0.1012
Toxoplasma gondii glutamine-dependent NAD(+) synthetase protein, putative 0.0094 0.0249 0.2351
Brugia malayi MH2 domain containing protein 0.0253 0.0746 0.241
Entamoeba histolytica acyl-CoA synthetase, putative 0.0027 0.0039 0.0139
Plasmodium falciparum cysteine proteinase falcipain 3 0.0035 0.0065 0.0379
Trichomonas vaginalis Clan CA, family C1, papain-like cysteine peptidase 0.0035 0.0065 0.0319
Brugia malayi Cathepsin L-like precursor 0.0035 0.0065 0.0207
Trichomonas vaginalis Clan CD, family C14, metacaspase-like cysteine peptidase 0.002 0.0017 0.0086
Trichomonas vaginalis lipid A export ATP-binding/permease protein msba, putative 0.0024 0.003 0.0146
Leishmania major cathepsin L-like protease 0.0135 0.0376 0.0553
Onchocerca volvulus Cathepsin F homolog 0.0035 0.0065 0.0192
Brugia malayi sodium-independent organic anion transporter family protein 0.0128 0.0354 0.1144
Brugia malayi MH1 domain containing protein 0.0017 0.0008 0.0023
Brugia malayi Cathepsin L-like precursor 0.0024 0.0028 0.0088
Trypanosoma cruzi PAB1-binding protein , putative 0.0029 0.0044 0.0064
Brugia malayi hypothetical protein 0.0033 0.0056 0.018
Loa Loa (eye worm) hypothetical protein 0.0064 0.0155 0.05
Plasmodium falciparum ADP-dependent DNA helicase RecQ 0.0038 0.0071 0.0425
Trypanosoma cruzi mitochondrial DNA polymerase beta-PAK, putative 0.0308 0.0915 0.1347
Toxoplasma gondii ABC transporter transmembrane region domain-containing protein 0.0024 0.003 0.0274
Trichomonas vaginalis conserved hypothetical protein 0.002 0.0017 0.0086
Echinococcus multilocularis geminin 0.0195 0.0563 0.0562
Trichomonas vaginalis lipid A export ATP-binding/permease protein msba, putative 0.0024 0.003 0.0146
Echinococcus multilocularis beta LACTamase domain containing family member 0.0041 0.0083 0.0082
Schistosoma mansoni family S12 unassigned peptidase (S12 family) 0.0041 0.0083 0.017
Schistosoma mansoni hypothetical protein 0.0048 0.0103 0.0212
Brugia malayi Ligand-binding domain of nuclear hormone receptor family protein 0.0062 0.0148 0.0475
Schistosoma mansoni jumonji/arid domain-containing protein 0.0137 0.0382 0.0788
Trichomonas vaginalis Clan CA, family C1, cathepsin L or K-like cysteine peptidase 0.0035 0.0065 0.0319
Schistosoma mansoni mixed-lineage leukemia protein mll 0.0139 0.0389 0.0803
Brugia malayi Muscleblind-like protein 0.0339 0.1012 0.3272
Echinococcus multilocularis cpg binding protein 0.0069 0.0169 0.0168
Echinococcus granulosus cathepsin l cysteine peptidase 0.0035 0.0065 0.0132
Loa Loa (eye worm) cytochrome P450 family protein 0.0034 0.0059 0.0187
Trypanosoma cruzi mitogen activated protein kinase 2, putative 0.0116 0.0315 0.0463
Loa Loa (eye worm) doublecortin family protein 0.0064 0.0155 0.05
Echinococcus multilocularis ATP binding cassette subfamily B (MDR:TAP) 0.0024 0.003 0.0029
Echinococcus multilocularis nuclear receptor nhr 48 0.0029 0.0045 0.0045
Loa Loa (eye worm) hypothetical protein 0.0029 0.0045 0.0144
Echinococcus granulosus histone lysine methyltransferase setb 0.0036 0.0066 0.0134
Mycobacterium tuberculosis Probable fatty-acid-CoA ligase FadD7 (fatty-acid-CoA synthetase) (fatty-acid-CoA synthase) 0.0019 0.0014 0.0038
Trichomonas vaginalis glucosylceramidase, putative 0.0195 0.0562 0.2778
Plasmodium vivax glutamine-dependent NAD(+) synthetase, putative 0.0094 0.0249 0.3916
Schistosoma mansoni DNA helicase recq5 0.0027 0.0038 0.0076
Loa Loa (eye worm) glutaminase 2 0.0314 0.0936 0.3024
Schistosoma mansoni TGF-beta signal transducer Smad2 0.0017 0.0008 0.0015
Mycobacterium tuberculosis Probable hydrolase 0.0041 0.0083 0.0232
Toxoplasma gondii CMGC kinase, MAPK family (ERK) MAPK-1 0.0116 0.0315 0.2977
Brugia malayi hypothetical protein 0.0272 0.0803 0.2596
Brugia malayi Melibiase family protein 0.0079 0.0199 0.0642
Onchocerca volvulus 0.0128 0.0354 0.113
Brugia malayi calcium-independent alpha-latrotoxin receptor 2, putative 0.0048 0.0103 0.0332
Brugia malayi Death domain containing protein 0.0017 0.0006 0.0016
Echinococcus multilocularis bloom syndrome protein 0.004 0.008 0.0079
Echinococcus multilocularis inositol monophosphatase 1 0.0042 0.0087 0.0086
Schistosoma mansoni hepatocyte nuclear factor 4-alpha (hnf-4-alpha) 0.0029 0.0045 0.0092
Trypanosoma cruzi mitochondrial DNA polymerase beta, putative 0.2188 0.6789 1
Brugia malayi Nuclear hormone receptor family member nhr-19 0.0062 0.0148 0.0475
Brugia malayi steroid hormone receptor 0.0062 0.0148 0.0475
Brugia malayi Carboxylesterase family protein 0.0123 0.0338 0.1089
Brugia malayi Cathepsin L-like precursor 0.0024 0.0028 0.0088
Brugia malayi nuclear receptor RXR 0.0029 0.0045 0.0144
Brugia malayi hypothetical protein 0.0033 0.0056 0.018
Echinococcus multilocularis ATP binding cassette subfamily B (MDR:TAP) 0.0024 0.003 0.0029
Toxoplasma gondii hypothetical protein 0.0353 0.1056 1
Trichomonas vaginalis glucosylceramidase, putative 0.0195 0.0562 0.2778
Onchocerca volvulus 0.0035 0.0065 0.0192
Loa Loa (eye worm) hypothetical protein 0.0024 0.0028 0.0088
Mycobacterium tuberculosis Glutamine-dependent NAD(+) synthetase NadE (NAD(+) synthase [glutamine-hydrolysing]) 0.0094 0.0249 0.0698
Loa Loa (eye worm) carboxylesterase 0.0123 0.0338 0.1089
Echinococcus granulosus TGF beta signal transducer SmadC 0.0017 0.0008 0.0015
Echinococcus granulosus tar DNA binding protein 0.0073 0.0181 0.0373
Echinococcus multilocularis Jumonji, AT rich interactive domain 1B 0.0039 0.0077 0.0076
Onchocerca volvulus Putative organic anion transporter 0.0128 0.0354 0.113
Toxoplasma gondii ATP-dependent DNA helicase, RecQ family protein 0.0024 0.0029 0.0265
Plasmodium vivax ataxin-2 like protein, putative 0.0029 0.0044 0.0551
Trypanosoma brucei protein kinase, putative 0.0116 0.0315 0.0463
Trichomonas vaginalis glucosylceramidase, putative 0.0195 0.0562 0.2778
Echinococcus granulosus dnaJ subfamily B 0.0928 0.2852 0.5888
Schistosoma mansoni mixed-lineage leukemia protein mll 0.0017 0.0008 0.0016
Loa Loa (eye worm) hypothetical protein 0.0128 0.0354 0.1144
Brugia malayi Cathepsin L-like cysteine proteinase 0.0024 0.0028 0.0088
Echinococcus multilocularis JmjC domain containing protein 4 0.0036 0.0065 0.0064
Schistosoma mansoni histone-lysine n-methyltransferase setb1 0.0036 0.0066 0.0134
Echinococcus multilocularis ATP binding cassette subfamily B (MDR:TAP) 0.0024 0.003 0.0029
Loa Loa (eye worm) jmjC domain-containing protein 0.0036 0.0065 0.0208
Echinococcus multilocularis FTZ F1 nuclear receptor protein 0.0062 0.0148 0.0147
Echinococcus granulosus mitogen activated protein kinase 3 0.0116 0.0315 0.0649
Echinococcus granulosus Jumonji AT rich interactive domain 1B 0.0039 0.0077 0.0157
Leishmania major ATP-dependent DEAD/H DNA helicase recQ, putative 0.003 0.0046 0.0067
Mycobacterium tuberculosis Probable chain -fatty-acid-CoA ligase FadD13 (fatty-acyl-CoA synthetase) 0.0027 0.0039 0.0108
Schistosoma mansoni SmCL2-like peptidase (C01 family) 0.0018 0.0011 0.0021
Schistosoma mansoni jumonji/arid domain-containing protein 0.0137 0.0382 0.0788
Loa Loa (eye worm) hypothetical protein 0.0029 0.0045 0.0144
Onchocerca volvulus 0.0041 0.0083 0.0252
Schistosoma mansoni Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) 0.0097 0.0257 0.0528
Brugia malayi AMP-binding enzyme family protein 0.0027 0.0039 0.0124
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0135 0.0376 0.0553
Echinococcus granulosus mixed lineage leukemia protein mll 0.0017 0.0008 0.0016
Schistosoma mansoni Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) 0.0097 0.0257 0.0528
Loa Loa (eye worm) hypothetical protein 0.0062 0.0148 0.0475
Schistosoma mansoni hypothetical protein 0.0064 0.0155 0.0319
Brugia malayi F/Y-rich N-terminus family protein 0.0021 0.002 0.0062
Brugia malayi Steroid receptor seven-up type 2 0.0062 0.0148 0.0475
Trypanosoma brucei metacaspase MCA3 0.002 0.0017 0.0025
Loa Loa (eye worm) O-glycosyl hydrolase family 30 protein 0.0297 0.0881 0.2849
Loa Loa (eye worm) hypothetical protein 0.0033 0.0056 0.018
Echinococcus multilocularis guanine nucleotide binding protein G(s) subunit 0.0097 0.0257 0.0256
Mycobacterium tuberculosis Probable transmembrane multidrug efflux pump 0.0024 0.003 0.0081
Loa Loa (eye worm) jmjC domain-containing protein 0.0036 0.0065 0.0208
Loa Loa (eye worm) hypothetical protein 0.002 0.0018 0.0054
Trichomonas vaginalis glucosylceramidase, putative 0.0195 0.0562 0.2778
Echinococcus granulosus retinoic acid receptor rxr beta a 0.0175 0.0502 0.1035
Echinococcus granulosus lamin dm0 0.0023 0.0027 0.0054
Onchocerca volvulus 0.0088 0.0227 0.0719
Trichomonas vaginalis glucosylceramidase, putative 0.0297 0.0881 0.4353
Echinococcus multilocularis Smad4 0.0017 0.0008 0.0007
Echinococcus granulosus beta LACTamase domain containing family member 0.0041 0.0083 0.017
Trypanosoma cruzi NAD+ synthase, putative 0.0094 0.0249 0.0366
Trichomonas vaginalis Clan CA, family C1, papain-like cysteine peptidase 0.0035 0.0065 0.0319
Toxoplasma gondii histone lysine demethylase JMJD6a 0.0036 0.0065 0.0609
Trypanosoma cruzi metacaspase, putative 0.002 0.0017 0.0025
Schistosoma mansoni smad1 5 8 and 0.0017 0.0008 0.0015
Leishmania major mitogen activated protein kinase, putative,map kinase, putative 0.0116 0.0315 0.0463
Schistosoma mansoni cpg binding protein 0.0069 0.0169 0.0347
Brugia malayi ecdysteroid receptor 0.0062 0.0148 0.0475
Brugia malayi Uncoordinated protein 44 0.0017 0.0006 0.0016
Mycobacterium ulcerans hypothetical protein 0.1152 0.3554 1
Loa Loa (eye worm) hypothetical protein 0.0126 0.0347 0.1119
Mycobacterium ulcerans NAD synthetase 0.0094 0.0249 0.0698
Plasmodium falciparum enoyl-acyl carrier reductase 0.0213 0.0619 0.4283
Trichomonas vaginalis lipid A export ATP-binding/permease protein msba, putative 0.0024 0.003 0.0146
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0135 0.0376 0.0553
Loa Loa (eye worm) RecQ helicase 0.004 0.008 0.0257
Mycobacterium tuberculosis NADH-dependent enoyl-[acyl-carrier-protein] reductase InhA (NADH-dependent enoyl-ACP reductase) 0.0213 0.0619 0.1739
Trypanosoma cruzi ATP-dependent DEAD/H DNA helicase recQ, putative 0.003 0.0046 0.0067
Trichomonas vaginalis Clan CA, family C1, papain-like cysteine peptidase 0.0035 0.0065 0.0319
Loa Loa (eye worm) hypothetical protein 0.0128 0.0354 0.1144
Trichomonas vaginalis myo inositol monophosphatase, putative 0.0042 0.0087 0.0427
Loa Loa (eye worm) hypothetical protein 0.0036 0.0065 0.0208
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0018 0.0011 0.0015
Trypanosoma cruzi hypothetical protein, conserved 0.0041 0.0083 0.0122
Loa Loa (eye worm) cysteine protease 0.0035 0.0065 0.0207
Schistosoma mansoni phosphatidylserine receptor 0.0036 0.0065 0.0133
Loa Loa (eye worm) ATP-dependent DNA helicase 0.0027 0.0038 0.0119
Loa Loa (eye worm) agrin synaptic family protein 0.0088 0.0227 0.0733
Loa Loa (eye worm) multidrug resistance protein 3 0.0024 0.003 0.0094
Trichomonas vaginalis Clan CA, family C1, papain-like cysteine peptidase 0.0035 0.0065 0.0319
Leishmania major metacaspase, putative 0.002 0.0017 0.0025
Schistosoma mansoni nuclear receptor nhr-48 0.0029 0.0045 0.0092
Echinococcus multilocularis cathepsin l cysteine peptidase 0.0035 0.0065 0.0064
Echinococcus multilocularis histone lysine N methyltransferase SETMAR 0.0036 0.0066 0.0065
Onchocerca volvulus Huntingtin homolog 0.0106 0.0285 0.0907
Schistosoma mansoni tar DNA-binding protein 0.0073 0.0181 0.0373
Echinococcus multilocularis caspase 2 0.0068 0.0165 0.0165
Leishmania major cathepsin L-like protease 0.0035 0.0065 0.0094
Echinococcus multilocularis cysteine protease 0.0035 0.0065 0.0064
Echinococcus multilocularis Ankyrin 0.0017 0.0006 0.0005
Loa Loa (eye worm) hypothetical protein 0.0151 0.0426 0.1375
Mycobacterium tuberculosis Probable fructose-bisphosphate aldolase Fba 0.0324 0.0966 0.2715
Echinococcus granulosus COUP TF:Svp nuclear hormone receptor 0.0062 0.0148 0.0303
Schistosoma mansoni SmCL2-like peptidase (C01 family) 0.0018 0.0011 0.0021
Loa Loa (eye worm) hypothetical protein 0.0088 0.0227 0.0733
Schistosoma mansoni nuclear hormone receptor 0.0029 0.0045 0.0092
Leishmania major hypothetical protein, conserved 0.0029 0.0044 0.0064
Loa Loa (eye worm) nuclear receptor nhr-7B 0.0029 0.0045 0.0144
Trichomonas vaginalis conserved hypothetical protein 0.002 0.0017 0.0086
Loa Loa (eye worm) nuclear hormone receptor family member nhr-40 0.0062 0.0148 0.0475
Echinococcus granulosus guanine nucleotide binding protein Gs subunit 0.0097 0.0257 0.0528
Echinococcus granulosus ecdysone induced protein 78C 0.0062 0.0148 0.0303
Echinococcus multilocularis lamin dm0 0.0023 0.0027 0.0026
Echinococcus granulosus nuclear receptor subfamily 1 group D 0.0033 0.0056 0.0115
Plasmodium falciparum metacaspase-like protein 0.002 0.0017 0.0046
Brugia malayi Cytochrome P450 family protein 0.0055 0.0127 0.0408
Echinococcus multilocularis Glycoside hydrolase, family 27 0.0118 0.0322 0.0321
Schistosoma mansoni rab6-interacting 0.0064 0.0155 0.0319
Brugia malayi hypothetical protein 0.0029 0.0045 0.0144
Schistosoma mansoni follistatin 0.0088 0.0227 0.0468
Trichomonas vaginalis alpha-galactosidase/alpha-N-acetylgalactosaminidase, putative 0.0079 0.0199 0.0984
Schistosoma mansoni agrin 0.0088 0.0227 0.0468
Plasmodium vivax hypothetical protein, conserved 0.0041 0.0083 0.1189
Loa Loa (eye worm) hypothetical protein 0.0041 0.0083 0.0267
Mycobacterium tuberculosis Probable fatty-acid-CoA ligase FadD5 (fatty-acid-CoA synthetase) (fatty-acid-CoA synthase) 0.0019 0.0014 0.0038
Loa Loa (eye worm) runx1 0.0126 0.0348 0.1122
Trichomonas vaginalis multidrug resistance protein 1, 2, putative 0.0024 0.003 0.0146
Echinococcus granulosus Basic leucine zipper bZIP transcription 0.0041 0.0083 0.017
Loa Loa (eye worm) kazal-type serine protease inhibitor domain-containing protein 0.0088 0.0227 0.0733
Echinococcus granulosus hepatocyte nuclear factor 4 alpha 0.0062 0.0148 0.0303
Trichomonas vaginalis multidrug resistance protein 1, 2, putative 0.0024 0.003 0.0146
Brugia malayi Nuclear hormone receptor E75 0.0029 0.0045 0.0144
Brugia malayi Cathepsin L-like precursor 0.0035 0.0065 0.0207
Loa Loa (eye worm) hypothetical protein 0.0029 0.0045 0.0144
Echinococcus multilocularis guanine nucleotide binding protein G(s) subunit 0.0097 0.0257 0.0256
Echinococcus granulosus nuclear receptor nhr 48 0.0029 0.0045 0.0092
Leishmania major cathepsin L-like protease 0.0035 0.0065 0.0094
Onchocerca volvulus 0.0029 0.0045 0.0129
Toxoplasma gondii ATP-binding cassette transporter ABC.B1 0.0024 0.003 0.0274
Onchocerca volvulus 0.0035 0.0065 0.0192
Mycobacterium tuberculosis Probable lipase LipE 0.0041 0.0083 0.0232
Echinococcus granulosus caspase 8 0.002 0.0017 0.0035
Trichomonas vaginalis multidrug resistance protein 1, 2, putative 0.0024 0.003 0.0146
Schistosoma mansoni Smad4 0.0017 0.0008 0.0015
Loa Loa (eye worm) Smad1 0.0017 0.0008 0.0023
Echinococcus granulosus phd:f box containing protein 0.0036 0.0065 0.0133
Toxoplasma gondii ATP-dependent DNA helicase, RecQ family protein 0.0027 0.0038 0.0348
Echinococcus granulosus Smad4 0.0017 0.0008 0.0015
Loa Loa (eye worm) beta-lactamase 0.0041 0.0083 0.0267
Echinococcus granulosus cysteine protease 0.0018 0.0011 0.0021
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0035 0.0065 0.0319
Trichomonas vaginalis chromodomain helicase DNA binding protein, putative 0.0015 0.000000000034474 0.00000000017026
Plasmodium falciparum JmjC domain-containing protein, putative 0.0036 0.0065 0.0381
Echinococcus multilocularis histone lysine N methyltransferase MLL3 0.0021 0.0021 0.002
Loa Loa (eye worm) hypothetical protein 0.0062 0.0148 0.0475
Schistosoma mansoni thyroid hormone receptor 0.0062 0.0148 0.0303
Trichomonas vaginalis DNA helicase recq1, putative 0.004 0.008 0.0396
Mycobacterium leprae PROBABLE FATTY-ACID-CoA LIGASE FADD7 (FATTY-ACID-CoA SYNTHETASE) (FATTY-ACID-CoA SYNTHASE) 0.0027 0.0039 0.0268
Echinococcus granulosus GMP synthase glutamine hydrolyzing 0.0038 0.0072 0.0147
Loa Loa (eye worm) hypothetical protein 0.0088 0.0227 0.0733
Echinococcus granulosus guanine nucleotide binding protein Gs subunit 0.0097 0.0257 0.0528
Mycobacterium ulcerans DNA-directed RNA polymerase subunit beta 0.0472 0.143 0.4021
Schistosoma mansoni family S9 non-peptidase homologue (S09 family) 0.0021 0.0019 0.0037
Trypanosoma cruzi cysteine peptidase, putative 0.0035 0.0065 0.0094
Schistosoma mansoni serine/threonine protein kinase 0.0116 0.0315 0.0649
Loa Loa (eye worm) hypothetical protein 0.0062 0.0148 0.0475
Schistosoma mansoni tar DNA-binding protein 0.0073 0.0181 0.0373
Trichomonas vaginalis DNA helicase recq, putative 0.004 0.008 0.0396
Schistosoma mansoni Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) 0.0097 0.0257 0.0528
Echinococcus granulosus bloom syndrome protein 0.004 0.008 0.0164
Loa Loa (eye worm) hypothetical protein 0.0029 0.0045 0.0144
Schistosoma mansoni blooms syndrome DNA helicase 0.0027 0.0038 0.0076
Echinococcus granulosus para nitrobenzyl esterase 0.0021 0.0019 0.0037
Schistosoma mansoni jumonji domain containing protein 0.0133 0.0371 0.0764
Mycobacterium tuberculosis Probable esterase LipL 0.0041 0.0083 0.0232
Trypanosoma brucei Metacaspase-4 0.002 0.0017 0.0025
Echinococcus granulosus nuclear receptor 2DBD gamma 0.0062 0.0148 0.0303
Echinococcus multilocularis mothers against decapentaplegic 5 0.0017 0.0008 0.0007
Toxoplasma gondii Kazal-type serine protease inhibitor domain-containing protein 0.0088 0.0227 0.2147
Loa Loa (eye worm) hypothetical protein 0.0027 0.0038 0.0119
Toxoplasma gondii Kazal-type serine protease inhibitor domain-containing protein 0.0088 0.0227 0.2147
Onchocerca volvulus 0.0024 0.003 0.0078
Brugia malayi Carboxylesterase family protein 0.0123 0.0338 0.1089
Brugia malayi nuclear receptor NHR-88 0.0029 0.0045 0.0144
Trichomonas vaginalis glucosylceramidase, putative 0.0195 0.0562 0.2778
Loa Loa (eye worm) hypothetical protein 0.0027 0.0039 0.0124
Mycobacterium tuberculosis Carboxylesterase LipT 0.0021 0.0019 0.0051
Brugia malayi Hypothetical 52.5 kDa protein ZK945.1 in chromosome II, putative 0.0041 0.0083 0.0267
Onchocerca volvulus Steroid hormone receptor family member cnr14 homolog 0.0062 0.0148 0.0461
Brugia malayi nuclear hormone receptor 0.0029 0.0045 0.0144
Brugia malayi hypothetical protein 0.0128 0.0354 0.1144
Schistosoma mansoni netrin receptor unc5 0.0017 0.0006 0.001
Leishmania major cathepsin L-like protease 0.0035 0.0065 0.0094
Onchocerca volvulus 0.0041 0.0083 0.0252
Brugia malayi jmjC domain containing protein 0.0036 0.0065 0.0208
Trichomonas vaginalis ABC transporter, half transporter, putative 0.0024 0.003 0.0146
Onchocerca volvulus 0.0041 0.0083 0.0252
Schistosoma mansoni glutaminase 0.0314 0.0936 0.1931
Echinococcus multilocularis Solute carrier organic anion transporter family 0.0128 0.0354 0.0354
Loa Loa (eye worm) sodium-independent organic anion transporter 0.0128 0.0354 0.1144
Trichomonas vaginalis Clan CD, family C14, metacaspase-like cysteine peptidase 0.002 0.0017 0.0086
Echinococcus multilocularis ATP binding cassette subfamily B (MDR:TAP) 0.0024 0.003 0.0029
Trichomonas vaginalis lipid A export ATP-binding/permease protein msba, putative 0.0024 0.003 0.0146
Brugia malayi ABC transporter family protein 0.0024 0.003 0.0094
Echinococcus multilocularis phd:f box containing protein 0.0036 0.0065 0.0064
Leishmania major mitochondrial DNA polymerase beta 0.2188 0.6789 1
Mycobacterium tuberculosis Fatty-acid-AMP ligase FadD30 (fatty-acid-AMP synthetase) (fatty-acid-AMP synthase) 0.002 0.0018 0.0047
Echinococcus granulosus agrin 0.0088 0.0227 0.0468
Echinococcus granulosus diuretic hormone 44 receptor GPRdih2 0.0048 0.0103 0.0212
Trypanosoma cruzi cytochrome P450, putative 0.0034 0.0059 0.0085
Onchocerca volvulus Glucosylceramidase homolog 0.0195 0.0562 0.1804
Trypanosoma cruzi JmjC domain, hydroxylase, putative 0.0036 0.0065 0.0095
Echinococcus multilocularis diuretic hormone 44 receptor GPRdih2 0.0048 0.0103 0.0103
Loa Loa (eye worm) ctsf protein 0.0035 0.0065 0.0207
Echinococcus granulosus lysine specific demethylase 5A 0.0137 0.0382 0.0788
Trichomonas vaginalis lipid A export ATP-binding/permease protein msba, putative 0.0024 0.003 0.0146
Plasmodium falciparum acyl-CoA synthetase 0.002 0.0018 0.0046
Trichomonas vaginalis Clan CA, family C1, cathepsin L or K-like cysteine peptidase 0.0035 0.0065 0.0319
Echinococcus multilocularis apoptotic protease activating factor 1 0.0047 0.0102 0.0101
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0035 0.0065 0.0319
Mycobacterium ulcerans acyl-CoA synthetase 0.0027 0.0039 0.0108
Trypanosoma cruzi major cysteine proteinase, putative 0.0106 0.0286 0.042
Brugia malayi Cathepsin L-like precursor 0.0035 0.0065 0.0207
Echinococcus multilocularis ATP binding cassette sub family B 0.0024 0.0029 0.0028
Loa Loa (eye worm) hypothetical protein 0.0041 0.0083 0.0267
Echinococcus granulosus nuclear receptor 2DBD gamma 0.0029 0.0045 0.0092
Echinococcus multilocularis agrin 0.0088 0.0227 0.0227
Loa Loa (eye worm) hypothetical protein 0.002 0.0018 0.0054
Brugia malayi Protein kinase domain containing protein 0.0018 0.0009 0.0026
Brugia malayi nuclear receptor subfamily 1, group D, member 1, putative 0.0029 0.0045 0.0144
Onchocerca volvulus 0.0021 0.0019 0.0043
Onchocerca volvulus Nuclear receptor subfamily 6 group A member 1 homolog 0.0029 0.0045 0.0129
Schistosoma mansoni nuclear receptor 0.0029 0.0045 0.0092
Loa Loa (eye worm) hypothetical protein 0.0021 0.0019 0.0058
Trypanosoma brucei RNA helicase, putative 0.0111 0.0301 0.0442
Echinococcus multilocularis jumonji domain containing 1A 0.0036 0.0065 0.0064
Loa Loa (eye worm) hypothetical protein 0.0128 0.0354 0.1144
Brugia malayi CXXC zinc finger family protein 0.0065 0.0157 0.0507
Trypanosoma brucei NAD+ synthase, putative 0.0094 0.0249 0.0366
Brugia malayi Intermediate filament tail domain containing protein 0.0023 0.0027 0.0085
Brugia malayi MH2 domain containing protein 0.0017 0.0008 0.0023
Schistosoma mansoni glutamine-dependent NAD(+) synthetase 0.0057 0.0131 0.0269
Treponema pallidum DNA-directed RNA polymerase subunit beta 0.0472 0.143 0.6649
Echinococcus granulosus cathepsin L cysteine protease 0.0018 0.0011 0.0021
Loa Loa (eye worm) hypothetical protein 0.0019 0.0012 0.0036
Schistosoma mansoni smad 0.0017 0.0008 0.0015
Brugia malayi hypothetical protein 0.0029 0.0045 0.0144
Schistosoma mansoni jumonji domain containing protein 0.0036 0.0065 0.0133
Schistosoma mansoni protein phosphatase 2C 0.0036 0.0065 0.0133
Echinococcus multilocularis ATP dependent DNA helicase Q1 0.0027 0.0038 0.0037
Brugia malayi Nuclear hormone receptor family member nhr-1 0.0062 0.0148 0.0475
Loa Loa (eye worm) Papain cysteine protease/cathepsin propeptide inhibitor-containing protein 0.0035 0.0065 0.0207
Brugia malayi nuclear hormone receptor family member odr-7 0.0029 0.0045 0.0144
Mycobacterium ulcerans esterase/lipase LipP 0.0041 0.0083 0.0232
Echinococcus granulosus multidrug resistance protein 1 0.0024 0.003 0.006
Echinococcus granulosus multidrug resistance protein 1 0.0024 0.003 0.006
Brugia malayi nuclear hormone receptor 0.0062 0.0148 0.0475
Brugia malayi beta-lactamase family protein 0.0041 0.0083 0.0267
Onchocerca volvulus 0.0035 0.0065 0.0192
Entamoeba histolytica fructose-1,6-bisphosphate aldolase, putative 0.0663 0.2025 1
Trichomonas vaginalis Clan CA, family C1, papain-like cysteine peptidase 0.0035 0.0065 0.0319
Trichomonas vaginalis Clan CA, family C1, papain-like cysteine peptidase 0.0035 0.0065 0.0319
Schistosoma mansoni GMP synthetase 0.0038 0.0072 0.0147
Loa Loa (eye worm) hypothetical protein 0.0024 0.0028 0.0088
Brugia malayi AMP-binding enzyme family protein 0.0027 0.0039 0.0124
Onchocerca volvulus 0.0027 0.0039 0.0109
Brugia malayi hypothetical protein 0.0128 0.0354 0.1144
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0035 0.0065 0.0319
Plasmodium vivax hypothetical protein, conserved 0.002 0.0017 0.0107
Brugia malayi Carboxylesterase family protein 0.0021 0.0019 0.0058
Leishmania major mitochondrial DNA polymerase beta-PAK, putative 0.1035 0.3189 0.4696
Plasmodium vivax multidrug resistance protein 1, putative 0.0024 0.003 0.0307
Echinococcus multilocularis Transcription factor, JmjC domain containing protein 0.0133 0.0371 0.037
Loa Loa (eye worm) hypothetical protein 0.0064 0.0155 0.05
Brugia malayi nuclear receptor NHR-88 0.0062 0.0148 0.0475
Loa Loa (eye worm) hypothetical protein 0.0272 0.0803 0.2596
Trypanosoma brucei inositol-1(or 4)-monophosphatase 1, putative 0.0042 0.0087 0.0126
Echinococcus multilocularis family S9 non peptidase ue (S09 family) 0.0021 0.0019 0.0018
Toxoplasma gondii bifunctional GMP synthase/glutamine amidotransferase protein 0.0038 0.0072 0.0674
Toxoplasma gondii ABC1 family protein 0.0041 0.0083 0.0781
Plasmodium falciparum metacaspase 1 0.002 0.0017 0.0046
Echinococcus granulosus follistatin 0.0088 0.0227 0.0468
Plasmodium falciparum ataxin-2 like protein, putative 0.0029 0.0044 0.0236
Loa Loa (eye worm) hypothetical protein 0.0024 0.003 0.0094
Echinococcus multilocularis FTZ F1 alpha 0.0062 0.0148 0.0147
Echinococcus multilocularis hepatocyte nuclear factor 4 alpha 0.0062 0.0148 0.0147
Loa Loa (eye worm) hypothetical protein 0.0033 0.0056 0.018
Trypanosoma cruzi transcription factor btf3, putative 0.004 0.0079 0.0116
Trichomonas vaginalis conserved hypothetical protein 0.002 0.0017 0.0086
Loa Loa (eye worm) hypothetical protein 0.0021 0.0019 0.0058
Echinococcus multilocularis nuclear receptor subfamily 1 group D 0.0033 0.0056 0.0056
Schistosoma mansoni caspase-7 (C14 family) 0.002 0.0017 0.0035
Trichomonas vaginalis set domain proteins, putative 0.0274 0.0809 0.3996
Onchocerca volvulus 0.0128 0.0354 0.113
Leishmania major cathepsin L-like protease 0.0035 0.0065 0.0094
Brugia malayi Nuclear hormone receptor-like 1 0.0033 0.0056 0.018
Giardia lamblia Fructose-bisphosphate aldolase 0.0663 0.2025 1
Echinococcus multilocularis thyroid hormone receptor alpha 0.0062 0.0148 0.0147
Schistosoma mansoni FTZ-F1 nuclear receptor-like protein 0.0062 0.0148 0.0303
Echinococcus granulosus ATP binding cassette subfamily B MDR:TAP 0.0024 0.003 0.006
Mycobacterium leprae PROBABLE GLUTAMINE-DEPENDENT NAD(+) SYNTHETASE NADE (NAD(+) SYNTHASE [GLUTAMINE-HYDROLYSING]) 0.0094 0.0249 0.1737
Loa Loa (eye worm) hypothetical protein 0.0088 0.0227 0.0733
Schistosoma mansoni organic anion transporter 0.0128 0.0354 0.073
Echinococcus granulosus ATP binding cassette subfamily B MDR:TAP 0.0024 0.003 0.006
Trichomonas vaginalis glucosylceramidase, putative 0.0205 0.0595 0.294
Mycobacterium leprae Probable fructose bisphosphate aldolase Fba 0.0324 0.0966 0.6752
Onchocerca volvulus 0.0064 0.0155 0.0485
Brugia malayi MAP kinase sur-1 0.0116 0.0315 0.1016
Schistosoma mansoni alpha-galactosidase/alpha-n-acetylgalactosaminidase 0.0079 0.0199 0.041
Chlamydia trachomatis enoyl-acyl-carrier protein reductase 0.0213 0.0619 0.4256
Loa Loa (eye worm) hypothetical protein 0.0088 0.0227 0.0733
Trichomonas vaginalis conserved hypothetical protein 0.002 0.0017 0.0086
Schistosoma mansoni histone-lysine n-methyltransferase suv9 0.0036 0.0066 0.0134
Echinococcus granulosus carboxylesterase 5A 0.0123 0.0338 0.0695
Loa Loa (eye worm) hypothetical protein 0.0062 0.0148 0.0475
Mycobacterium tuberculosis Probable lipase LipD 0.0041 0.0083 0.0232
Loa Loa (eye worm) hypothetical protein 0.0041 0.0083 0.0267
Loa Loa (eye worm) hypothetical protein 0.0029 0.0044 0.0141
Schistosoma mansoni loxhd1 0.0064 0.0155 0.0319
Onchocerca volvulus 0.0274 0.081 0.2605
Entamoeba histolytica P-glyco protein 6, putative 0.0024 0.003 0.0093
Echinococcus multilocularis nuclear receptor 2DBD gamma 0.0062 0.0148 0.0147
Mycobacterium leprae conserved hypothetical protein 0.0041 0.0083 0.0577
Loa Loa (eye worm) RNA binding protein 0.0073 0.0181 0.0584
Echinococcus multilocularis cathepsin L cysteine protease 0.0035 0.0065 0.0064
Trichomonas vaginalis glutaminase, putative 0.0314 0.0936 0.4621
Echinococcus granulosus caspase 2 0.0068 0.0165 0.034
Brugia malayi Corticotropin releasing factor receptor 2 precursor, putative 0.0151 0.0426 0.1375
Schistosoma mansoni hypothetical protein 0.0047 0.0102 0.0209
Plasmodium falciparum cysteine proteinase falcipain 2a 0.0035 0.0065 0.0379
Brugia malayi GTP-binding regulatory protein Gs alpha-S chain, putative 0.0097 0.0257 0.0827
Loa Loa (eye worm) nuclear hormone receptor-like 1 0.0033 0.0056 0.018
Echinococcus granulosus intermediate filament protein 0.0023 0.0027 0.0054
Mycobacterium tuberculosis Probable fatty-acid-CoA ligase FadD2 (fatty-acid-CoA synthetase) (fatty-acid-CoA synthase) 0.0027 0.0039 0.0108
Trypanosoma cruzi DNA polymerase beta thumb, putative 0.0308 0.0915 0.1347
Loa Loa (eye worm) hypothetical protein 0.0038 0.0072 0.023
Trypanosoma cruzi cysteine peptidase, putative 0.0135 0.0376 0.0553
Brugia malayi beta-NAC-like protein 0.004 0.0079 0.0255
Brugia malayi Nuclear hormone receptor family member nhr-19 0.0062 0.0148 0.0475
Loa Loa (eye worm) hypothetical protein 0.0103 0.0277 0.0892
Mycobacterium ulcerans GMP synthase 0.0038 0.0072 0.02
Loa Loa (eye worm) fibroinase 0.0035 0.0065 0.0207
Schistosoma mansoni multidrug resistance protein 0.0024 0.003 0.006
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0024 0.0028 0.0139
Echinococcus granulosus inositol monophosphatase 1 0.0042 0.0087 0.0177
Brugia malayi conserved hypotetical protein 0.0029 0.0045 0.0144
Trichomonas vaginalis fructose-bisphosphate aldolase, putative 0.0663 0.2025 1
Trichomonas vaginalis fructose-bisphosphate aldolase, putative 0.0663 0.2025 1
Trypanosoma cruzi metacaspase 5, putative 0.002 0.0017 0.0025
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0135 0.0376 0.0553
Trichomonas vaginalis CMGC family protein kinase 0.0116 0.0315 0.1555
Onchocerca volvulus 0.0023 0.0027 0.0069
Brugia malayi Inositol-1 0.0042 0.0087 0.0278
Trypanosoma cruzi myo-inositol-1(or 4)-monophosphatase 1, putative 0.0042 0.0087 0.0126
Loa Loa (eye worm) CMGC/MAPK/ERK1 protein kinase 0.0116 0.0315 0.1016
Loa Loa (eye worm) hypothetical protein 0.0036 0.0065 0.0208
Brugia malayi mucosa associated lymphoid tissue lymphoma translocation protein 1 0.002 0.0017 0.0054
Echinococcus granulosus transcription factor btf3 0.004 0.0079 0.0163
Loa Loa (eye worm) hypothetical protein 0.0128 0.0354 0.1144
Echinococcus multilocularis Alpha N acetylgalactosaminidase 0.0118 0.0322 0.0321
Mycobacterium ulcerans fructose-bisphosphate aldolase 0.0324 0.0966 0.2715
Trichomonas vaginalis Clan CD, family C14, metacaspase-like cysteine peptidase 0.002 0.0017 0.0086
Schistosoma mansoni glutamine-dependent NAD(+) synthetase 0.0094 0.0249 0.0512
Schistosoma mansoni hypothetical protein 0.0017 0.0006 0.001
Onchocerca volvulus 0.0036 0.0066 0.0194
Plasmodium vivax GMP synthetase, putative 0.0038 0.0072 0.1002
Echinococcus granulosus Alpha N acetylgalactosaminidase 0.0118 0.0322 0.0663
Schistosoma mansoni ecdysone-induced protein 78c (dr-78) 0.0033 0.0056 0.0115
Loa Loa (eye worm) hypothetical protein 0.0128 0.0354 0.1144
Schistosoma mansoni tar DNA-binding protein 0.0073 0.0181 0.0373
Mycobacterium tuberculosis Probable fatty-acid-CoA ligase FadD35 (fatty-acid-CoA synthetase) (fatty-acid-CoA synthase) 0.0019 0.0014 0.0038
Giardia lamblia NH3-dependent NAD+ synthetase 0.0094 0.0249 0.1064
Entamoeba histolytica fructose-1,6-bisphosphate aldolase, putative 0.0663 0.2025 1
Echinococcus multilocularis muscleblind protein 1 0.0339 0.1012 0.1012
Loa Loa (eye worm) hypothetical protein 0.0062 0.0148 0.0475
Loa Loa (eye worm) jmjC domain-containing protein 0.0036 0.0065 0.0208
Loa Loa (eye worm) nuclear hormone receptor family member nhr-14 0.0062 0.0148 0.0475
Trichomonas vaginalis spcc417.12 protein, putative 0.0021 0.0019 0.0092
Loa Loa (eye worm) hypothetical protein 0.0023 0.0027 0.0085
Onchocerca volvulus Cathepsin L homolog 0.0035 0.0065 0.0192
Loa Loa (eye worm) cytochrome P450 family protein 0.0055 0.0127 0.0408
Entamoeba histolytica P-glycoprotein-5 0.0024 0.003 0.0093
Echinococcus granulosus thyroid hormone receptor alpha 0.0029 0.0045 0.0092
Plasmodium falciparum cysteine proteinase falcipain 2b 0.0035 0.0065 0.0379
Trichomonas vaginalis myo inositol monophosphatase, putative 0.0042 0.0087 0.0427
Loa Loa (eye worm) pigment dispersing factor receptor c 0.0151 0.0426 0.1375
Echinococcus granulosus survival motor neuron protein 1 0.0272 0.0803 0.1657
Trichomonas vaginalis glucosylceramidase, putative 0.0297 0.0881 0.4353
Schistosoma mansoni inositol monophosphatase 0.0042 0.0087 0.0177
Trypanosoma brucei metacaspase 0.002 0.0017 0.0025
Echinococcus multilocularis follistatin 0.0088 0.0227 0.0227
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0035 0.0065 0.0319
Trichomonas vaginalis fructose-bisphosphate aldolase, putative 0.0663 0.2025 1
Trichomonas vaginalis multidrug resistance protein 1, 2, putative 0.0024 0.003 0.0146
Entamoeba histolytica P-glycoprotein-2 0.0024 0.003 0.0093
Echinococcus multilocularis multidrug resistance protein 1 0.0024 0.003 0.0029
Schistosoma mansoni cathepsin F (C01 family) 0.0035 0.0065 0.0132
Onchocerca volvulus 0.1005 0.3092 1
Trypanosoma cruzi cysteine peptidase, putative 0.0018 0.0011 0.0015
Trypanosoma cruzi metacaspase, putative 0.002 0.0017 0.0025
Onchocerca volvulus 0.0128 0.0354 0.113
Mycobacterium tuberculosis Possible conserved lipoprotein LpqK 0.0041 0.0083 0.0232
Brugia malayi tailless protein 0.0029 0.0045 0.0144
Mycobacterium leprae possible inositol monophosphatase SubH (IMPase) (inositol-1-phosphatase) (I-1-Pase ). 0.0038 0.0073 0.0503
Trichomonas vaginalis carboxylesterase domain containing protein, putative 0.0021 0.0019 0.0092
Entamoeba histolytica cysteine proteinase, putative 0.0035 0.0065 0.0267

Activities

Activity type Activity value Assay description Source Reference
IC50 (binding) = 13 uM In vitro inhibition of Torpedo californica acetylcholinesterase. ChEMBL. 10052979

Phenotypes

Whole-cell/tissue/organism interactions

We have no records of whole-cell/tissue assays done with this compound What does this mean?

Many chemical entities in TDR Targets come from high-throughput screenings with whole cells or tissue samples, and not all assayed compounds have been tested against a single a single target protein, probably because they get ruled out during screening process. Even if these compounds may have not been of interest in the original screening, they may come as interesting leads for other screening assays. Furthermore, we may be able to propose drug-target associations using chemical similarities and network patterns.

Annotated phenotypes:

We have no manually annotated phenotypes for this drug. What does this mean? / Care to help?
In TDR Targets, information about phenotypes that are caused by drugs, or by genetic manipulation of cells (e.g. gene knockouts or knockdowns) is manually curated from the literature. These descriptions help to describe the potential of the target for drug development. If no information is available for this gene or if the information is incomplete, this may mean that i) the papers containing this information either appeared after the curation effort for this organism was carried out or they were inadvertently missed by curators; or that ii) the curation effort for this organism has not yet started.
 
In any case, if you have information about papers containing relevant validation data for this target, please log in using your TDR Targets username and password and send them to us using the corresponding form in this page (only visible to registered users) or contact us.

External resources for this compound

Bibliographic References

1 literature reference was collected for this gene.

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