Detailed information for compound 314146

Basic information

Technical information
  • Name: Unnamed compound
  • MW: 492.471 | Formula: C21H32O13
  • H donors: 7 H acceptors: 7 LogP: -2.76 Rotable bonds: 9
    Rule of 5 violations (Lipinski): 2
  • SMILES: OCC1OC(OCC2OC(OCc3ccc(cc3OC)OC)C(C(C2O)O)O)C(C(C1O)O)O
  • InChi: 1S/C21H32O13/c1-29-10-4-3-9(11(5-10)30-2)7-31-20-19(28)17(26)15(24)13(34-20)8-32-21-18(27)16(25)14(23)12(6-22)33-21/h3-5,12-28H,6-8H2,1-2H3
  • InChiKey: IJSKBWDPEQHAJZ-UHFFFAOYSA-N  


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Synonyms

No synonyms found for this compound

Targets

Known targets for this compound

No curated genes were found associated with this compound

Predicted pathogen targets for this compound

By orthology
No druggable targets predicted by orthology data
By sequence similarity to non orthologous known druggable targets
No druggable targets predicted by sequence similarity
Obtained from network model

Ranking Plot

Putative Targets List

Species Potential target Raw Global Species
Mycobacterium ulcerans aldehyde dehydrogenase 0.0064 0.0373 1
Brugia malayi metabotropic GABA-B receptor subtype 2 0.0035 0.0173 0.0552
Echinococcus granulosus calpain A 0.0064 0.0376 0.1038
Trypanosoma brucei antigen, putative 0.0018 0.0057 0.0232
Entamoeba histolytica exodeoxyribonuclease III, putative 0.002 0.0069 0.0279
Schistosoma mansoni calpain-7 (C02 family) 0.0018 0.0057 0.0157
Loa Loa (eye worm) histone methyltransferase 0.0028 0.0127 0.0127
Echinococcus multilocularis endoplasmin 0.0044 0.0237 0.0654
Trypanosoma cruzi phospholipase A1, putative 0.035 0.2356 0.9622
Echinococcus multilocularis mixed lineage leukemia protein mll 0.0023 0.009 0.0249
Schistosoma mansoni sodium-dependent neurotransmitter transporter 0.0033 0.0158 0.0436
Entamoeba histolytica Rab geranylgeranyltransferase beta subunit, putative 0.0022 0.0084 0.0339
Trichomonas vaginalis chromodomain helicase DNA binding protein, putative 0.002 0.0069 0.0379
Plasmodium vivax heat shock protein 90, putative 0.0031 0.0147 0.1265
Echinococcus multilocularis tyrosine kinase 0.002 0.0071 0.0197
Plasmodium falciparum isocitrate dehydrogenase [NADP], mitochondrial 0.0032 0.0152 0.1307
Loa Loa (eye worm) hypothetical protein 0.0053 0.0297 0.0297
Plasmodium vivax importin-beta 2, putative 0.0033 0.0162 0.1387
Trypanosoma brucei geranylgeranyl transferase type II beta subunit, putative 0.0022 0.0084 0.0343
Trypanosoma brucei sterol 24-c-methyltransferase, putative 0.0198 0.1304 0.5327
Giardia lamblia Dynamin 0.0022 0.0086 0.0352
Brugia malayi PHD-finger family protein 0.0015 0.0035 0.0113
Loa Loa (eye worm) prenyltransferase and squalene oxidase repeat family protein 0.0022 0.0084 0.0084
Echinococcus multilocularis Ataxin 2, N terminal,domain containing protein 0.0024 0.0094 0.0261
Mycobacterium tuberculosis Probable chaperone protein HtpG (heat shock protein) (HSP90 family protein) (high temperature protein G) 0.0044 0.0237 0.1297
Trypanosoma cruzi hypothetical protein, conserved 0.0038 0.0193 0.0788
Trypanosoma cruzi cysteine peptidase, Clan CA, family C2, putative 0.0018 0.0057 0.0232
Echinococcus granulosus neuropeptide s receptor 0.0401 0.2715 0.7508
Toxoplasma gondii Sodium:neurotransmitter symporter family protein 0.0033 0.0158 0.1354
Leishmania major lipophosphoglycan biosynthetic protein, putative,heat shock protein 90, putative,glucose regulated protein 94, putative 0.0044 0.0237 0.1004
Trypanosoma brucei kinesin, putative 0.0018 0.0057 0.0232
Schistosoma mansoni metabotropic glutamate receptor 0.0105 0.0657 0.1818
Echinococcus multilocularis cyclin dependent kinase 1 0.0043 0.0232 0.0641
Brugia malayi TAR-binding protein 0.013 0.0831 0.2657
Trypanosoma brucei importin beta-1 subunit, putative 0.0033 0.0162 0.066
Brugia malayi Sodium:neurotransmitter symporter family protein 0.0033 0.0158 0.0504
Echinococcus granulosus tar DNA binding protein 0.013 0.0831 0.2299
Echinococcus granulosus aldehyde dehydrogenase mitochondrial 0.0064 0.0373 0.1031
Loa Loa (eye worm) hypothetical protein 0.0031 0.0145 0.0145
Trypanosoma brucei heat shock protein 84, putative 0.0031 0.0147 0.0602
Loa Loa (eye worm) CXXC zinc finger family protein 0.0088 0.0538 0.0538
Leishmania major heat shock protein 83-1 0.0047 0.0257 0.1089
Trypanosoma brucei Sterol methyltransferase, putative 0.0198 0.1304 0.5327
Plasmodium falciparum dynamin-like protein 0.0022 0.0086 0.0737
Leishmania major heat shock protein 83-1 0.0047 0.0257 0.1089
Plasmodium falciparum protein kinase 5 0.0043 0.0232 0.1989
Trypanosoma cruzi heat shock protein, putative 0.0031 0.0147 0.0602
Echinococcus multilocularis nmda type glutamate receptor 0.002 0.0071 0.0197
Echinococcus granulosus beta LACTamase domain containing family member 0.0038 0.0193 0.0534
Schistosoma mansoni sodium-dependent neurotransmitter transporter 0.0033 0.0158 0.0436
Schistosoma mansoni dynamin 0.0022 0.0086 0.0237
Leishmania major apurinic/apyrimidinic endonuclease-redox protein 0.002 0.0069 0.0295
Trypanosoma cruzi hypothetical protein, conserved 0.0022 0.0084 0.0343
Echinococcus multilocularis histone lysine N methyltransferase MLL3 0.0023 0.009 0.0249
Trypanosoma brucei heat shock protein, putative 0.0047 0.0257 0.1048
Loa Loa (eye worm) hypothetical protein 0.0043 0.0228 0.0228
Schistosoma mansoni dynamin 0.0024 0.0098 0.027
Entamoeba histolytica calpain large subunit domain III containing protein 0.0018 0.0057 0.0226
Trichomonas vaginalis chromodomain helicase DNA binding protein, putative 0.002 0.0069 0.0379
Plasmodium vivax hypothetical protein, conserved 0.0038 0.0193 0.1656
Echinococcus multilocularis lamin dm0 0.0023 0.0092 0.0255
Trypanosoma cruzi extracellular receptor, putative 0.002 0.0071 0.0291
Entamoeba histolytica acetyltransferase, GNAT family 0.0039 0.02 0.0825
Brugia malayi calcium-independent alpha-latrotoxin receptor 2, putative 0.0079 0.0481 0.1537
Loa Loa (eye worm) GTP-binding nuclear protein RAN/TC4 0.0024 0.0101 0.0101
Trichomonas vaginalis conserved hypothetical protein 0.002 0.0069 0.0379
Trypanosoma brucei calpain-like protein, putative 0.0018 0.0057 0.0232
Loa Loa (eye worm) hypothetical protein 0.0033 0.0158 0.0158
Loa Loa (eye worm) cytochrome P450 0.0015 0.0033 0.0033
Mycobacterium leprae possible inositol monophosphatase SubH (IMPase) (inositol-1-phosphatase) (I-1-Pase ). 0.0036 0.018 0.7234
Schistosoma mansoni mixed-lineage leukemia protein mll 0.0014 0.0026 0.0072
Brugia malayi Importin beta-1 subunit 0.0033 0.0162 0.0517
Leishmania major heat shock protein 83-1 0.0047 0.0257 0.1089
Plasmodium vivax hypothetical protein, conserved 0.0031 0.0145 0.1242
Trypanosoma cruzi Heat shock protein 83, putative 0.0047 0.0257 0.1048
Toxoplasma gondii Rab geranylgeranyl transferase type II beta subunit, putative 0.0022 0.0084 0.0721
Entamoeba histolytica geranylgeranyl transferase beta subunit 0.0022 0.0084 0.0339
Leishmania major GTP-binding protein, putative 0.0024 0.0101 0.0428
Loa Loa (eye worm) hypothetical protein 0.0061 0.0354 0.0354
Toxoplasma gondii isocitrate dehydrogenase 0.0032 0.0152 0.1307
Echinococcus granulosus lamin dm0 0.0023 0.0092 0.0255
Trypanosoma brucei isocitrate dehydrogenase [NADP], mitochondrial precursor, putative 0.0032 0.0152 0.0622
Brugia malayi hypothetical protein 0.0244 0.162 0.5178
Entamoeba histolytica hypothetical protein 0.002 0.0071 0.0286
Echinococcus granulosus mixed lineage leukemia protein mll 0.0023 0.009 0.0249
Toxoplasma gondii LsmAD domain-containing protein 0.0052 0.0295 0.2531
Trichomonas vaginalis conserved hypothetical protein 0.002 0.0069 0.0379
Plasmodium vivax heat shock protein 86, putative 0.0047 0.0257 0.2203
Schistosoma mansoni lamin 0.0023 0.0092 0.0255
Echinococcus multilocularis Jumonji, AT rich interactive domain 1B 0.0015 0.0035 0.0096
Loa Loa (eye worm) hypothetical protein 0.0024 0.0098 0.0098
Loa Loa (eye worm) hypothetical protein 0.0244 0.162 0.162
Toxoplasma gondii heat shock protein HSP90 0.0047 0.0257 0.2203
Giardia lamblia Heat shock protein HSP 90-alpha 0.0047 0.0257 0.1063
Loa Loa (eye worm) calpain 5 0.0018 0.0057 0.0057
Trypanosoma cruzi heat shock protein 85, putative 0.0047 0.0257 0.1048
Entamoeba histolytica peptidase, C54 family 0.0047 0.0258 0.1064
Brugia malayi beta-lactamase family protein 0.0038 0.0193 0.0617
Echinococcus multilocularis calpain 7 (C02 family) 0.0018 0.0057 0.0157
Leishmania major calpain-like cysteine peptidase, putative,cysteine peptidase, Clan CA, family C2, putative 0.0018 0.0057 0.0241
Trypanosoma cruzi phospholipase A1, putative 0.035 0.2356 0.9622
Trypanosoma brucei heat shock protein, putative 0.0047 0.0257 0.1048
Trichomonas vaginalis chromodomain helicase DNA binding protein, putative 0.002 0.0069 0.0379
Trichomonas vaginalis heat shock protein, putative 0.0034 0.0167 0.0966
Brugia malayi latrophilin 2 splice variant baaae 0.0171 0.1119 0.3576
Loa Loa (eye worm) jmjC domain-containing protein 0.0042 0.0224 0.0224
Echinococcus multilocularis isocitrate dehydrogenase 0.0032 0.0152 0.0421
Loa Loa (eye worm) 3-hydroxyacyl-CoA dehydrogenase type II 0.0046 0.0251 0.0251
Onchocerca volvulus Vesicular acetylcholine transporter homolog 0.0461 0.3129 0.308
Brugia malayi acetyltransferase, GNAT family protein 0.0144 0.0931 0.2974
Echinococcus granulosus GPCR family 3 C terminal 0.0035 0.0173 0.0478
Trichomonas vaginalis geranylgeranyl transferase type beta subunit, putative 0.0022 0.0084 0.047
Leishmania major heat shock protein 83-1 0.0047 0.0257 0.1089
Echinococcus granulosus 5'partial|histone lysine N methyltransferase SETDB2 0.0031 0.0143 0.0394
Loa Loa (eye worm) RGC/RGC protein kinase 0.002 0.0071 0.0071
Brugia malayi isocitrate dehydrogenase 0.0032 0.0152 0.0487
Loa Loa (eye worm) CMGC/CDK/CDC2 protein kinase 0.0043 0.0232 0.0232
Schistosoma mansoni cyclin-dependent kinase 5 activator 0.0257 0.1714 0.474
Loa Loa (eye worm) ATP-dependent DNA helicase 0.001 0.0001 0.0001
Echinococcus multilocularis importin subunit beta 1 0.0033 0.0162 0.0447
Echinococcus granulosus heat shock protein 0.0047 0.0257 0.071
Leishmania major AUT2/APG4/ATG4 cysteine peptidase, putative 0.0121 0.0769 0.3264
Trypanosoma cruzi cytochrome p450-like protein, putative 0.0015 0.0033 0.0134
Giardia lamblia DNA repair protein RAD52 0.0356 0.2401 1
Trypanosoma brucei Lanosterol 14-alpha demethylase 0.0015 0.0033 0.0134
Echinococcus multilocularis glutamate receptor 2 0.002 0.0071 0.0197
Onchocerca volvulus Ceramide glucosyltransferase homolog 0.023 0.1529 0.1468
Onchocerca volvulus 0.0033 0.0158 0.0087
Trypanosoma cruzi PAB1-binding protein , putative 0.0052 0.0295 0.1204
Echinococcus granulosus PHD finger protein rhinoceros 0.0031 0.0145 0.04
Entamoeba histolytica heat shock protein 90, putative 0.0047 0.0257 0.1059
Trypanosoma cruzi lanosterol synthase, putative 0.0363 0.2449 1
Toxoplasma gondii hypothetical protein 0.0033 0.0158 0.1354
Plasmodium vivax endoplasmin, putative 0.0047 0.0257 0.2203
Schistosoma mansoni family S12 unassigned peptidase (S12 family) 0.0038 0.0193 0.0534
Trypanosoma cruzi calpain cysteine peptidase, putative 0.0018 0.0057 0.0232
Loa Loa (eye worm) hypothetical protein 0.0033 0.0158 0.0158
Loa Loa (eye worm) hypothetical protein 0.0264 0.1765 0.1765
Trichomonas vaginalis chromodomain-helicase-DNA-binding protein, putative 0.002 0.0069 0.0379
Trypanosoma cruzi protein farnesyltransferase, putative 0.0022 0.0084 0.0343
Brugia malayi hypothetical protein 0.0123 0.0785 0.2508
Plasmodium falciparum transporter, putative 0.0033 0.0158 0.1354
Trichomonas vaginalis interferon-induced GTP-binding protein mx, putative 0.0022 0.0086 0.0481
Trypanosoma brucei isocitrate dehydrogenase, putative 0.0032 0.0152 0.0622
Trichomonas vaginalis dynamin, putative 0.0022 0.0086 0.0481
Schistosoma mansoni NADP-specific isocitrate dehydrogenase 0.0032 0.0152 0.0421
Schistosoma mansoni heat shock protein 0.0047 0.0257 0.071
Loa Loa (eye worm) hypothetical protein 0.002 0.0071 0.0071
Entamoeba histolytica hypothetical protein 0.0027 0.0118 0.0481
Loa Loa (eye worm) CYP4Cod1 0.0015 0.0033 0.0033
Loa Loa (eye worm) hypothetical protein 0.0061 0.0354 0.0354
Toxoplasma gondii autophagy-related cysteine peptidase atg4, putative 0.0047 0.0258 0.2214
Brugia malayi Prenyltransferase and squalene oxidase repeat family protein 0.0022 0.0084 0.0268
Brugia malayi metabotropic glutamate receptor subtype 5a (mGluR5a), putative 0.0195 0.1281 0.4094
Brugia malayi beta-lactamase family protein 0.0038 0.0193 0.0617
Echinococcus multilocularis glutamate receptor, ionotrophic, AMPA 3 0.002 0.0071 0.0197
Schistosoma mansoni hypothetical protein 0.0531 0.3616 1
Echinococcus granulosus GTP binding nuclear protein Ran 0.0024 0.0101 0.0279
Mycobacterium tuberculosis Probable esterase/lipase LipP 0.0038 0.0193 0.1019
Loa Loa (eye worm) hypothetical protein 0.0257 0.1714 0.1714
Echinococcus granulosus dynamin 1 protein 0.0022 0.0086 0.0237
Leishmania major hypothetical protein, conserved 0.0052 0.0295 0.1251
Trichomonas vaginalis penicillin-binding protein, putative 0.0038 0.0193 0.1118
Echinococcus multilocularis dynamin 1 0.0024 0.0098 0.027
Leishmania major heat shock protein 83-1 0.0047 0.0257 0.1089
Trichomonas vaginalis endoplasmin, putative 0.0034 0.0167 0.0966
Echinococcus multilocularis Glutamate receptor, ionotropic kainate 2 0.002 0.0071 0.0197
Loa Loa (eye worm) hypothetical protein 0.0035 0.0173 0.0173
Schistosoma mansoni geranylgeranyl transferase type II beta subunit 0.0022 0.0084 0.0232
Toxoplasma gondii isocitrate dehydrogenase 0.0032 0.0152 0.1307
Trypanosoma cruzi sterol 24-c-methyltransferase, putative 0.0198 0.1304 0.5327
Plasmodium vivax amine transporter, putative 0.0033 0.0158 0.1354
Loa Loa (eye worm) hypothetical protein 0.0382 0.2581 0.2581
Toxoplasma gondii histone lysine methyltransferase SET1 0.017 0.1113 0.9556
Mycobacterium tuberculosis Probable exodeoxyribonuclease III protein XthA (exonuclease III) (EXO III) (AP endonuclease VI) 0.002 0.0069 0.0233
Echinococcus granulosus cpg binding protein 0.0092 0.0572 0.1583
Schistosoma mansoni tyrosine kinase 0.002 0.0071 0.0197
Leishmania major ATP-dependent DEAD/H DNA helicase recQ, putative 0.0013 0.0022 0.0094
Trypanosoma brucei protein farnesyltransferase beta subunit 0.0022 0.0084 0.0343
Trichomonas vaginalis heat shock protein, putative 0.0044 0.0237 0.1378
Schistosoma mansoni tar DNA-binding protein 0.013 0.0831 0.2299
Schistosoma mansoni gcn5proteinral control of amino-acid synthesis 5-like 2 gcnl2 0.0144 0.0931 0.2573
Trypanosoma brucei importin beta-1 subunit, putative 0.0033 0.0162 0.066
Brugia malayi Sodium:neurotransmitter symporter family protein 1, putative 0.0033 0.0158 0.0504
Trypanosoma cruzi cdc2-related kinase 3 0.0043 0.0232 0.0946
Trypanosoma cruzi importin beta-1 subunit, putative 0.0027 0.0118 0.0482
Leishmania major cell division related protein kinase 2,cdc2-related kinase 0.0043 0.0232 0.0983
Entamoeba histolytica protein farnesyltransferase beta subunit, putative 0.0022 0.0084 0.0339
Loa Loa (eye worm) hypothetical protein 0.002 0.0071 0.0071
Brugia malayi Intermediate filament tail domain containing protein 0.0023 0.0092 0.0295
Schistosoma mansoni hypothetical protein 0.0407 0.2752 0.761
Toxoplasma gondii PHD-finger domain-containing protein 0.001 0.0001 0.0007
Schistosoma mansoni aldehyde dehydrogenase 0.0064 0.0373 0.1031
Brugia malayi Dynamin 0.0024 0.0098 0.0312
Trypanosoma cruzi phospholipase A2-like protein, putative 0.016 0.1043 0.426
Schistosoma mansoni hypothetical protein 0.0079 0.0481 0.133
Brugia malayi Ceramide glucosyltransferase 0.023 0.1529 0.4887
Brugia malayi metabotropic GABA-B receptor subtype 2 0.002 0.0071 0.0227
Loa Loa (eye worm) norepinephrine transporter 0.0033 0.0158 0.0158
Trypanosoma brucei sterol 24-c-methyltransferase, putative 0.0103 0.0647 0.2644
Trypanosoma cruzi isocitrate dehydrogenase, putative 0.0032 0.0152 0.0622
Brugia malayi metabotropic glutamate receptor type 2 0.0105 0.0657 0.2101
Leishmania major cytochrome p450-like protein 0.0015 0.0033 0.0139
Echinococcus granulosus Glutamate receptor ionotropic kainate 2 0.002 0.0071 0.0197
Echinococcus granulosus cyclin dependent kinase 1 0.0043 0.0232 0.0641
Loa Loa (eye worm) hypothetical protein 0.0022 0.0084 0.0084
Plasmodium vivax ADP-dependent DNA helicase RecQ, putative 0.0017 0.0046 0.0398
Schistosoma mansoni jumonji/arid domain-containing protein 0.0042 0.0224 0.062
Loa Loa (eye worm) hypothetical protein 0.002 0.0071 0.0071
Echinococcus multilocularis NADP dependent isocitrate dehydrogenase 0.0032 0.0152 0.0421
Schistosoma mansoni heat shock protein 0.0047 0.0257 0.071
Entamoeba histolytica dynamin-like protein 0.0022 0.0086 0.0347
Loa Loa (eye worm) hypothetical protein 0.002 0.0071 0.0071
Echinococcus multilocularis Transcription factor, JmjC domain containing protein 0.0101 0.0631 0.1744
Loa Loa (eye worm) hypothetical protein 0.0251 0.1669 0.1669
Trypanosoma brucei cytochrome P450, putative 0.0015 0.0033 0.0134
Echinococcus multilocularis dynamin 0.0022 0.0086 0.0237
Trypanosoma brucei heat shock protein, putative 0.0047 0.0257 0.1048
Schistosoma mansoni family C2 unassigned peptidase (C02 family) 0.0064 0.0376 0.1038
Trypanosoma cruzi cdc2-related kinase 1 0.0043 0.0232 0.0946
Echinococcus granulosus endoplasmin 0.0044 0.0237 0.0654
Leishmania major cell division protein kinase 2,cdc2-related kinase 0.0043 0.0232 0.0983
Schistosoma mansoni blooms syndrome DNA helicase 0.0019 0.0066 0.0182
Plasmodium falciparum phd finger protein, putative 0.0031 0.0145 0.1242
Trypanosoma cruzi Lanosterol 14-alpha demethylase 0.0015 0.0033 0.0134
Schistosoma mansoni jumonji domain containing protein 0.008 0.0487 0.1346
Brugia malayi Inositol-1 0.004 0.0209 0.0669
Trypanosoma brucei hypothetical protein, conserved 0.0038 0.0193 0.0788
Mycobacterium ulcerans short-chain type dehydrogenase/reductase 0.0049 0.0274 0.7097
Schistosoma mansoni sodium/chloride dependent neurotransmitter transporter 0.0216 0.1428 0.3949
Mycobacterium tuberculosis Probable short-chain type dehydrogenase/reductase 0.0049 0.0274 0.1535
Mycobacterium leprae Probable lipase LipE 0.0038 0.0193 0.7856
Loa Loa (eye worm) hypothetical protein 0.0038 0.0193 0.0193
Giardia lamblia Ceramide glucosyltransferase 0.0104 0.0655 0.2725
Echinococcus granulosus heat shock protein heat shock protein 90 alpha 0.004 0.021 0.058
Trypanosoma brucei apurinic/apyrimidinic endonuclease, putative 0.002 0.0069 0.0284
Loa Loa (eye worm) intermediate filament protein 0.0023 0.0092 0.0092
Schistosoma mansoni mixed-lineage leukemia protein mll 0.0033 0.016 0.0442
Trypanosoma cruzi heat shock protein 90, putative 0.0047 0.0257 0.1048
Schistosoma mansoni histone-lysine n-methyltransferase suv9 0.0034 0.0164 0.0453
Echinococcus multilocularis cytoplasmic intermediate filament protein 0.0011 0.0009 0.0025
Schistosoma mansoni norepinephrine/norepinephrine transporter 0.0033 0.0158 0.0436
Loa Loa (eye worm) hypothetical protein 0.0011 0.0006 0.0006
Treponema pallidum heat shock protein 90 0.0044 0.0237 1
Mycobacterium tuberculosis Possible conserved lipoprotein LpqK 0.0038 0.0193 0.1019
Schistosoma mansoni histone-lysine n-methyltransferase setb1 0.0034 0.0164 0.0453
Trypanosoma cruzi heat shock protein 90, putative 0.004 0.021 0.0856
Brugia malayi Isocitrate dehydrogenase 0.0032 0.0152 0.0487
Schistosoma mansoni inositol monophosphatase 0.004 0.0209 0.0579
Echinococcus granulosus receptor type guanylyl cyclase 0.002 0.0071 0.0197
Loa Loa (eye worm) RNA binding protein 0.013 0.0831 0.0831
Toxoplasma gondii cytochrome p450 superfamily protein 0.0015 0.0033 0.0282
Schistosoma mansoni hypothetical protein 0.005 0.0276 0.0762
Mycobacterium tuberculosis Inositol-1-monophosphatase SuhB 0.0036 0.018 0.0938
Schistosoma mansoni calpain C (C02 family) 0.0018 0.0057 0.0157
Loa Loa (eye worm) solute carrier family 6 member 4 0.0033 0.0158 0.0158
Toxoplasma gondii heat shock protein 90, putative 0.0047 0.0257 0.2203
Schistosoma mansoni importin beta-1 0.0033 0.0162 0.0447
Entamoeba histolytica peptidase, C54 family 0.0121 0.0769 0.3196
Leishmania major heat shock protein, putative 0.0031 0.0147 0.0625
Plasmodium vivax AP endonuclease (DNA-[apurinic or apyrimidinic site] lyase), putative 0.002 0.0069 0.0596
Schistosoma mansoni Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) 0.0092 0.0571 0.1578
Echinococcus multilocularis inositol monophosphatase 1 0.004 0.0209 0.0579
Leishmania major AUT2/APG4/ATG4 cysteine peptidase, putative 0.0047 0.0258 0.1094
Schistosoma mansoni calpain (C02 family) 0.0018 0.0057 0.0157
Schistosoma mansoni tar DNA-binding protein 0.013 0.0831 0.2299
Echinococcus granulosus peregrin 0.0034 0.0169 0.0468
Loa Loa (eye worm) glutamate receptor 0.0085 0.0517 0.0517
Echinococcus multilocularis musashi 0.0023 0.0092 0.0255
Schistosoma mansoni tar DNA-binding protein 0.013 0.0831 0.2299
Trypanosoma cruzi apurinic/apyrimidinic endonuclease 0.002 0.0069 0.0284
Loa Loa (eye worm) hypothetical protein 0.0052 0.0295 0.0295
Mycobacterium ulcerans exodeoxyribonuclease III protein XthA 0.002 0.0069 0.1077
Echinococcus granulosus uncharacterized sodium dependent transporter 0.0033 0.0158 0.0436
Toxoplasma gondii aldehyde dehydrogenase 0.0064 0.0373 0.3199
Schistosoma mansoni transcription factor LCR-F1 0.0064 0.0377 0.1042
Echinococcus multilocularis neuropeptide s receptor 0.0401 0.2715 0.7508
Echinococcus granulosus Peptidase C54 0.0121 0.0769 0.2127
Trichomonas vaginalis conserved hypothetical protein 0.002 0.0069 0.0379
Schistosoma mansoni hypothetical protein 0.0079 0.0481 0.133
Loa Loa (eye worm) hypothetical protein 0.0033 0.0162 0.0162
Loa Loa (eye worm) hypothetical protein 0.002 0.0071 0.0071
Plasmodium vivax dynamin-like protein, putative 0.0022 0.0086 0.0737
Leishmania major lanosterol 14-alpha-demethylase, putative 0.0015 0.0033 0.0139
Echinococcus granulosus Ataxin 2 N terminaldomain containing protein 0.0024 0.0094 0.0261
Trichomonas vaginalis chromodomain-helicase-DNA-binding protein, putative 0.0011 0.0005 0.00000000017254
Loa Loa (eye worm) cytochrome P450 family protein 0.0015 0.0033 0.0033
Wolbachia endosymbiont of Brugia malayi heat shock protein 90 0.0044 0.0237 1
Toxoplasma gondii prenyltransferase and squalene oxidase repeat-containing protein 0.0022 0.0084 0.0721
Leishmania major aldehyde dehydrogenase, mitochondrial precursor 0.0064 0.0373 0.1582
Echinococcus granulosus geranylgeranyl transferase type I beta subunit 0.0022 0.0084 0.0232
Trypanosoma brucei calpain-like cysteine peptidase, putative 0.0018 0.0057 0.0232
Schistosoma mansoni hypothetical protein 0.0024 0.0094 0.0261
Trichomonas vaginalis type I geranylgeranyltransferase beta subunit, putative 0.0022 0.0084 0.047
Trypanosoma brucei cdc2-related kinase 3 0.0043 0.0232 0.0946
Echinococcus granulosus ceramide glucosyltransferase 0.023 0.1529 0.4229
Onchocerca volvulus 0.0164 0.107 0.1006
Trichomonas vaginalis ap endonuclease, putative 0.002 0.0069 0.0384
Leishmania major heat shock protein 83-1 0.0047 0.0257 0.1089
Trypanosoma brucei lanosterol synthase 0.0363 0.2449 1
Toxoplasma gondii inositol(myo)-1(or 4)-monophosphatase 2, putative 0.004 0.0209 0.1798
Entamoeba histolytica hypothetical protein 0.0064 0.0377 0.1559
Trichomonas vaginalis CMGC family protein kinase 0.0043 0.0232 0.1348
Echinococcus granulosus guanine nucleotide binding protein Gs subunit 0.0092 0.0571 0.1578
Plasmodium vivax GTP-binding nuclear protein RAN/TC4, putative 0.0024 0.0101 0.0865
Echinococcus multilocularis geminin 0.0531 0.3616 1
Trypanosoma cruzi GTP-binding nuclear protein rtb2, putative 0.0024 0.0101 0.0411
Leishmania major cytochrome p450-like protein 0.0015 0.0033 0.0139
Trypanosoma cruzi cdc2-related kinase 3 0.0043 0.0232 0.0946
Echinococcus granulosus uncharacterized sodium dependent transporter 0.0033 0.0158 0.0436
Schistosoma mansoni family S12 unassigned peptidase (S12 family) 0.0038 0.0193 0.0534
Trichomonas vaginalis conserved hypothetical protein 0.002 0.0069 0.0379
Trypanosoma brucei cysteine peptidase, Clan CA, family C2, putative 0.0018 0.0057 0.0232
Schistosoma mansoni aldehyde dehydrogenase 0.0064 0.0373 0.1031
Echinococcus granulosus heat shock protein 90 0.004 0.021 0.058
Loa Loa (eye worm) hypothetical protein 0.001 0.0001 0.0001
Echinococcus granulosus metabotropic glutamate receptor 2 0.018 0.1179 0.3261
Echinococcus granulosus heat shock protein 75 kDa mitochondrial 0.0031 0.0147 0.0407
Plasmodium vivax geranylgeranyltransferase, putative 0.0022 0.0084 0.0721
Loa Loa (eye worm) hypothetical protein 0.0038 0.0193 0.0193
Echinococcus multilocularis cyclin dependent kinase 1 0.0043 0.0232 0.0641
Echinococcus granulosus histone lysine N methyltransferase MLL3 0.0023 0.009 0.0249
Trichomonas vaginalis dynamin, putative 0.0022 0.0086 0.0481
Brugia malayi Receptor family ligand binding region containing protein 0.0055 0.0313 0.1
Treponema pallidum sodium- and chloride- dependent transporter 0.0033 0.0158 0.5281
Brugia malayi hypothetical protein 0.0033 0.0158 0.0504
Giardia lamblia Histone acetyltransferase GCN5 0.0039 0.02 0.0829
Loa Loa (eye worm) RNA recognition domain-containing protein domain-containing protein 0.013 0.0831 0.0831
Echinococcus multilocularis calpain family protein 1, d 0.0043 0.0228 0.0631
Entamoeba histolytica cell division protein kinase 2, putative 0.0043 0.0232 0.0955
Leishmania major heat shock protein 83-1 0.0047 0.0257 0.1089
Loa Loa (eye worm) hypothetical protein 0.0033 0.0158 0.0158
Onchocerca volvulus 0.035 0.2356 0.2301
Brugia malayi Pre-SET motif family protein 0.0223 0.1476 0.4717
Trichomonas vaginalis D-aminoacylase, putative 0.0038 0.0193 0.1118
Plasmodium falciparum geranylgeranyl transferase type2 beta subunit, putative 0.0022 0.0084 0.0721
Schistosoma mansoni myst-related protein 0.001 0.0003 0.0007
Mycobacterium ulcerans heat shock protein 90 0.0044 0.0237 0.5996
Brugia malayi Sodium:neurotransmitter symporter family protein 0.0033 0.0158 0.0504
Leishmania major heat shock protein 83-1 0.0047 0.0257 0.1089
Trichomonas vaginalis dynamin, putative 0.0022 0.0086 0.0481
Brugia malayi Metabotropic glutamate receptor precursor. 0.0215 0.1421 0.4541
Schistosoma mansoni sodium/chloride dependent transporter 0.0033 0.0161 0.0445
Brugia malayi S-adenosyl-methionine cycloartenol-C24-methyltransferase 0.0097 0.06 0.1919
Echinococcus granulosus cyclin dependent kinase 5 0.0043 0.0232 0.0641
Trypanosoma cruzi cysteine peptidase, Clan CA, family C2, putative 0.0018 0.0057 0.0232
Echinococcus multilocularis Rab geranylgeranyltransferase, beta subunit 0.0022 0.0084 0.0232
Trichomonas vaginalis D-aminoacylase, putative 0.0038 0.0193 0.1118
Schistosoma mansoni histone-lysine n-methyltransferase setb1 0.0034 0.0164 0.0453
Echinococcus multilocularis GTP binding nuclear protein Ran 0.0024 0.0101 0.0279
Echinococcus multilocularis 0.0015 0.0033 0.0091
Loa Loa (eye worm) pigment dispersing factor receptor c 0.0251 0.1669 0.1669
Loa Loa (eye worm) hypothetical protein 0.0123 0.0785 0.0785
Mycobacterium tuberculosis Probable aldehyde dehydrogenase 0.0064 0.0373 0.2163
Brugia malayi AF-10 protein 0.001 0.0001 0.0003
Schistosoma mansoni cytochrome P450 0.0015 0.0033 0.0091
Trypanosoma cruzi kinesin, putative 0.0018 0.0057 0.0232
Brugia malayi Sodium:neurotransmitter symporter family protein 0.0033 0.0158 0.0504
Plasmodium falciparum histone acetyltransferase GCN5 0.0039 0.02 0.1721
Loa Loa (eye worm) isocitrate dehydrogenase 0.0032 0.0152 0.0152
Trichomonas vaginalis Clan CA, family C54, ATG4-like cysteine peptidase 0.0121 0.0769 0.4542
Brugia malayi Bromodomain containing protein 0.0034 0.0169 0.0541
Schistosoma mansoni family C54 unassigned peptidase (C54 family) 0.0121 0.0769 0.2127
Loa Loa (eye worm) hypothetical protein 0.0038 0.0193 0.0193
Brugia malayi calpain 7 0.0018 0.0057 0.0182
Brugia malayi RNA, U transporter 1 0.0095 0.0587 0.1875
Trypanosoma brucei cdc2-related kinase 1 0.0043 0.0232 0.0946
Echinococcus granulosus Transcription factor JmjC domain containing protein 0.0101 0.0631 0.1744
Schistosoma mansoni family C2 unassigned peptidase (C02 family) 0.0064 0.0376 0.1038
Plasmodium falciparum AP endonuclease (DNA-[apurinic or apyrimidinic site] lyase), putative 0.002 0.0069 0.0596
Echinococcus multilocularis Peptidase C54 0.0121 0.0769 0.2127
Leishmania major lanosterol synthase, putative 0.0341 0.2296 0.9744
Trypanosoma cruzi calpain-like cysteine peptidase, putative 0.0018 0.0057 0.0232
Trichomonas vaginalis inositol monophosphatase, putative 0.004 0.0209 0.1216
Trichomonas vaginalis dynamin, putative 0.0022 0.0086 0.0481
Loa Loa (eye worm) beta-LACTamase domain containing family member 0.0038 0.0193 0.0193
Echinococcus granulosus serotonin transporter 0.0033 0.0158 0.0436
Schistosoma mansoni Mername-AA248 (C02 family) 0.0018 0.0057 0.0157
Echinococcus granulosus DNA apurinic or apyrimidinic site lyase 0.002 0.0069 0.0192
Echinococcus granulosus metabotropic glutamate receptor 5 0.0264 0.1765 0.4882
Leishmania major importin beta-1 subunit, putative 0.0027 0.0118 0.0501
Toxoplasma gondii ATP-dependent DNA helicase, RecQ family protein 0.001 0.0001 0.0013
Leishmania major heat shock protein 83-1 0.0047 0.0257 0.1089
Schistosoma mansoni hypothetical protein 0.001 0.0001 0.0002
Loa Loa (eye worm) calpain family protein 1 0.0061 0.0354 0.0354
Schistosoma mansoni hypothetical protein 0.0079 0.0481 0.133
Schistosoma mansoni inositol monophosphatase 0.004 0.0209 0.0579
Echinococcus granulosus calpain 7 C02 family 0.0018 0.0057 0.0157
Trichomonas vaginalis conserved hypothetical protein 0.002 0.0069 0.0379
Trichomonas vaginalis myo inositol monophosphatase, putative 0.004 0.0209 0.1216
Toxoplasma gondii ABC1 family protein 0.0038 0.0193 0.1656
Trichomonas vaginalis geranylgeranyl transferase type I beta subunit, putative 0.0022 0.0084 0.047
Loa Loa (eye worm) receptor family ligand binding region containing protein 0.0055 0.0313 0.0313
Trypanosoma cruzi calpain-like cysteine peptidase, putative 0.0018 0.0057 0.0232
Echinococcus granulosus cyclin dependent kinase 5 activator 1 0.0257 0.1714 0.474
Loa Loa (eye worm) exodeoxyribonuclease III family protein 0.002 0.0069 0.0069
Echinococcus granulosus Jumonji AT rich interactive domain 1B 0.0015 0.0035 0.0096
Trypanosoma cruzi apurinic/apyrimidinic endonuclease, putative 0.002 0.0069 0.0284
Leishmania major heat shock protein 83-1 0.0047 0.0257 0.1089
Loa Loa (eye worm) hypothetical protein 0.0023 0.0092 0.0092
Schistosoma mansoni family C2 unassigned peptidase (C02 family) 0.0061 0.0354 0.0979
Schistosoma mansoni tyrosine kinase 0.002 0.0071 0.0197
Loa Loa (eye worm) ceramide glucosyltransferase 0.023 0.1529 0.1529
Trypanosoma brucei Heat shock protein 83, putative 0.0047 0.0257 0.1048
Trypanosoma brucei heat shock protein, putative 0.0047 0.0257 0.1048
Trichomonas vaginalis conserved hypothetical protein 0.002 0.0069 0.0379
Loa Loa (eye worm) beta-lactamase 0.0038 0.0193 0.0193
Schistosoma mansoni hypothetical protein 0.0531 0.3616 1
Trichomonas vaginalis DNA helicase recq, putative 0.0025 0.0102 0.0575
Giardia lamblia Endonuclease/Exonuclease/phosphatase 0.002 0.0069 0.0283
Loa Loa (eye worm) RGC/RGC protein kinase 0.002 0.0071 0.0071
Brugia malayi Dynamin 0.0024 0.0098 0.0312
Echinococcus multilocularis heat shock protein 75 kDa, mitochondrial 0.0031 0.0147 0.0407
Entamoeba histolytica DNA repair and recombination protein RAD52, putative 0.0356 0.2401 1
Echinococcus granulosus GPCR family 2 0.0079 0.0481 0.133
Brugia malayi F/Y-rich N-terminus family protein 0.0038 0.0194 0.0621
Brugia malayi Receptor family ligand binding region containing protein 0.002 0.0071 0.0227
Giardia lamblia Kinase, CMGC CDK 0.0043 0.0232 0.0959
Trypanosoma cruzi lanosterol synthase, putative 0.0363 0.2449 1
Echinococcus multilocularis metabotropic glutamate receptor 5 0.0264 0.1765 0.4882
Loa Loa (eye worm) Sodium:neurotransmitter symporter family protein 0.0033 0.0158 0.0158
Echinococcus granulosus lamin 0.0023 0.0092 0.0255
Loa Loa (eye worm) calpain 0.0018 0.0057 0.0057
Leishmania major sterol 24-c-methyltransferase, putative 0.0198 0.1304 0.5537
Trypanosoma cruzi Lanosterol 14-alpha demethylase 0.0015 0.0033 0.0134
Schistosoma mansoni ran 0.0024 0.0101 0.0279
Entamoeba histolytica hypothetical protein 0.0101 0.0634 0.2632
Echinococcus multilocularis jumonji domain containing protein 0.0043 0.0228 0.0631
Echinococcus granulosus cyclin dependent kinase 0.0043 0.0232 0.0641
Leishmania major heat shock protein 83-1 0.0047 0.0257 0.1089
Brugia malayi Cytochrome P450 family protein 0.0015 0.0033 0.0105
Schistosoma mansoni endoplasmin 0.0047 0.0257 0.071
Trypanosoma brucei PAB1-binding protein , putative 0.0052 0.0295 0.1204
Leishmania major heat shock protein 83-1 0.0047 0.0257 0.1089
Plasmodium falciparum ataxin-2 like protein, putative 0.0052 0.0295 0.2531
Leishmania major heat shock protein 83-1 0.0047 0.0257 0.1089
Entamoeba histolytica peptidase, C54 family 0.0047 0.0258 0.1064
Leishmania major sterol 24-c-methyltransferase, putative 0.0198 0.1304 0.5537
Schistosoma mansoni norepinephrine/norepinephrine transporter 0.0033 0.0158 0.0436
Loa Loa (eye worm) hypothetical protein 0.0038 0.0193 0.0193
Plasmodium vivax SET domain protein, putative 0.0034 0.0164 0.1408
Brugia malayi Iron-sulfur cluster assembly accessory protein 0.005 0.0276 0.0881
Echinococcus granulosus glutamate receptor 2 0.002 0.0071 0.0197
Toxoplasma gondii histone lysine acetyltransferase GCN5-A 0.0042 0.0225 0.1931
Echinococcus multilocularis glutamate receptor 2 0.002 0.0071 0.0197
Trichomonas vaginalis geranylgeranyl transferase type II beta subunit, putative 0.0022 0.0084 0.047
Plasmodium vivax calpain, putative 0.0018 0.0057 0.0488
Mycobacterium leprae PROBABLE CHAPERONE PROTEIN HTPG (HEAT SHOCK PROTEIN) (HSP90 FAMILY PROTEIN) (HIGH TEMPERATURE PROTEIN G) 0.0044 0.0237 1
Echinococcus granulosus tyrosine kinase 0.002 0.0071 0.0197
Giardia lamblia Prenyltransferase 0.0022 0.0084 0.0344
Echinococcus granulosus Glutamate receptor ionotropic kainate 2 0.002 0.0071 0.0197
Schistosoma mansoni protein kinase 0.002 0.0071 0.0197
Schistosoma mansoni heat shock protein 0.0031 0.0147 0.0407
Schistosoma mansoni Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) 0.0092 0.0571 0.1578
Plasmodium falciparum zinc finger protein, putative 0.001 0.0003 0.0023
Mycobacterium ulcerans extragenic suppressor protein SuhB 0.004 0.0209 0.5196
Loa Loa (eye worm) heat shock protein 75 0.0031 0.0147 0.0147
Brugia malayi CXXC zinc finger family protein 0.0088 0.0538 0.1719
Brugia malayi RNA binding protein 0.013 0.0831 0.2657
Entamoeba histolytica peptidase, C54 family 0.0047 0.0258 0.1064
Echinococcus granulosus histone lysine N methyltransferase MLL3 0.0028 0.0127 0.0351
Loa Loa (eye worm) transcription factor SMAD2 0.0107 0.0673 0.0673
Schistosoma mansoni hypothetical protein 0.0015 0.0033 0.0091
Loa Loa (eye worm) pre-SET domain-containing protein family protein 0.0223 0.1476 0.1476
Mycobacterium tuberculosis Probable lipase LipD 0.0038 0.0193 0.1019
Schistosoma mansoni hypothetical protein 0.0171 0.1119 0.3095
Trichomonas vaginalis esterase, putative 0.0038 0.0193 0.1118
Loa Loa (eye worm) metabotropic glutamate receptor 8 0.002 0.0071 0.0071
Entamoeba histolytica dynamin-1-like protein, putative 0.0022 0.0086 0.0347
Onchocerca volvulus Phospholipase A2 homolog 0.0382 0.2581 0.2527
Entamoeba histolytica hypothetical protein 0.0064 0.0377 0.1559
Trichomonas vaginalis dynamin, putative 0.0022 0.0086 0.0481
Trypanosoma brucei calpain-like protein, putative 0.0018 0.0057 0.0232
Toxoplasma gondii ATP-dependent DNA helicase, RecQ family protein 0.0016 0.0045 0.0386
Schistosoma mansoni sodium/chloride dependent neurotransmitter transporter 0.0216 0.1428 0.3949
Schistosoma mansoni cpg binding protein 0.0092 0.0572 0.1583
Plasmodium vivax ataxin-2 like protein, putative 0.0052 0.0295 0.2531
Echinococcus multilocularis beta LACTamase domain containing family member 0.0038 0.0193 0.0534
Entamoeba histolytica peptidase, C54 family 0.0047 0.0258 0.1064
Trichomonas vaginalis Clan CA, family C54, ATG4-like cysteine peptidase 0.0121 0.0769 0.4542
Echinococcus multilocularis histone lysine N methyltransferase SETMAR 0.0034 0.0164 0.0453
Trypanosoma brucei PHD-zinc-finger like domain containing protein, putative 0.001 0.0001 0.0004
Toxoplasma gondii PHD-finger domain-containing protein 0.0031 0.0145 0.1242
Echinococcus granulosus sodium and chloride dependent glycine 0.0033 0.0158 0.0436
Echinococcus granulosus calpain 5 0.0018 0.0057 0.0157
Plasmodium vivax hypothetical protein, conserved 0.0033 0.0158 0.1354
Onchocerca volvulus 0.0253 0.1687 0.1628
Plasmodium falciparum GTP-binding nuclear protein RAN/TC4 0.0024 0.0101 0.0865
Trypanosoma cruzi kinesin, putative 0.0018 0.0057 0.0232
Trichomonas vaginalis Importin beta-1 subunit, putative 0.0027 0.0118 0.0673
Echinococcus multilocularis geranylgeranyl transferase type I beta subunit 0.0022 0.0084 0.0232
Trichomonas vaginalis heat shock protein, putative 0.0047 0.0257 0.1496
Trypanosoma cruzi cysteine peptidase, Clan CA, family C2, putative 0.0018 0.0057 0.0232
Trichomonas vaginalis helicase, putative 0.002 0.0069 0.0379
Entamoeba histolytica hypothetical protein 0.0064 0.0377 0.1559
Brugia malayi beta-lactamase 0.0038 0.0193 0.0617
Echinococcus multilocularis PHD finger protein rhinoceros 0.0031 0.0145 0.04
Toxoplasma gondii exonuclease III APE 0.002 0.0069 0.0596
Echinococcus granulosus 3 hydroxyacyl coenzyme A dehydrogenase type 2 0.0049 0.0274 0.0758
Schistosoma mansoni protein farnesyltransferase subunit beta 0.0022 0.0084 0.0232
Toxoplasma gondii dynamin gtpase 0.0015 0.0033 0.0283
Brugia malayi calpain 5 0.0018 0.0057 0.0182
Loa Loa (eye worm) RecQ helicase 0.0025 0.0102 0.0102
Trypanosoma cruzi calpain-like cysteine peptidase, putative 0.0018 0.0057 0.0232
Loa Loa (eye worm) calpain family protein 1 0.0043 0.0228 0.0228
Schistosoma mansoni serine/threonine protein kinase 0.0043 0.0232 0.0641
Schistosoma mansoni jumonji/arid domain-containing protein 0.0042 0.0224 0.062
Brugia malayi PHD-finger family protein 0.0031 0.0145 0.0462
Brugia malayi hypothetical protein 0.002 0.0071 0.0227
Toxoplasma gondii hypothetical protein 0.0033 0.0158 0.1354
Entamoeba histolytica protein kinase, putative 0.0019 0.006 0.024
Loa Loa (eye worm) hypothetical protein 0.0216 0.1428 0.1428
Echinococcus multilocularis isocitrate dehydrogenase 2 (NADP+) 0.0032 0.0152 0.0421
Echinococcus multilocularis calpain A 0.0064 0.0376 0.1038
Trypanosoma brucei heat shock protein, putative 0.0047 0.0257 0.1048
Loa Loa (eye worm) hypothetical protein 0.0079 0.0481 0.0481
Echinococcus multilocularis cadherin EGF LAG seven pass G type receptor 0.0079 0.0481 0.133
Plasmodium vivax hypothetical protein, conserved 0.0015 0.0038 0.0325
Leishmania major heat shock protein 83-1 0.0047 0.0257 0.1089
Echinococcus multilocularis GPCR, family 2 0.0079 0.0481 0.133
Trypanosoma brucei AUT2/APG4/ATG4 cysteine peptidase, putative 0.0121 0.0769 0.3141
Brugia malayi Probable protein farnesyltransferase beta subunit, putative 0.0022 0.0084 0.0268
Brugia malayi intermediate filament protein 0.0023 0.0092 0.0295
Loa Loa (eye worm) glutamate receptor 0.0215 0.1421 0.1421
Echinococcus granulosus sodium and chloride dependent glycine 0.0033 0.0158 0.0436
Trypanosoma cruzi geranylgeranyl transferase type II beta subunit, putative 0.0022 0.0084 0.0343
Onchocerca volvulus Phospholipase A2 homolog 0.1452 1 1
Trypanosoma brucei heat shock protein 90, putative 0.0047 0.0257 0.1048
Onchocerca volvulus 0.0038 0.0193 0.0123
Trypanosoma cruzi PAB1-binding protein , putative 0.0052 0.0295 0.1204
Echinococcus granulosus cytochrome P450 2K1 0.0015 0.0033 0.0091
Loa Loa (eye worm) intermediate filament tail domain-containing protein 0.0023 0.0092 0.0092
Echinococcus multilocularis serotonin transporter 0.0033 0.0158 0.0436
Mycobacterium tuberculosis Probable esterase LipL 0.0038 0.0193 0.1019
Trypanosoma cruzi protein farnesyltransferase, putative 0.0022 0.0084 0.0343
Trypanosoma cruzi GTP-binding nuclear protein rtb2, putative 0.0024 0.0101 0.0411
Plasmodium falciparum heat shock protein 90, putative 0.0027 0.012 0.1033
Entamoeba histolytica myo-inositol monophosphatase, putative 0.004 0.0209 0.0862
Brugia malayi Prenyltransferase and squalene oxidase repeat family protein 0.0022 0.0084 0.0268
Leishmania major heat shock protein 83-1 0.0047 0.0257 0.1089
Trichomonas vaginalis CMGC family protein kinase 0.0043 0.0232 0.1348
Plasmodium falciparum conserved Plasmodium membrane protein, unknown function 0.0015 0.0038 0.0325
Schistosoma mansoni autophagin-1 (C54 family) 0.0121 0.0769 0.2127
Trypanosoma cruzi cysteine peptidase, Clan CA, family C2, putative 0.0018 0.0057 0.0232
Brugia malayi calpain family protein 1 0.0061 0.0354 0.1131
Plasmodium falciparum geranylgeranyltransferase, putative 0.0022 0.0084 0.0721
Schistosoma mansoni cpg binding protein 0.0088 0.0538 0.1487
Trichomonas vaginalis conserved hypothetical protein 0.002 0.0069 0.0379
Trichomonas vaginalis heat shock protein, putative 0.0027 0.012 0.0686
Brugia malayi cytochrome P450 0.0015 0.0033 0.0105
Loa Loa (eye worm) jmjC domain-containing protein 0.0064 0.0372 0.0372
Trypanosoma brucei heat shock protein, putative 0.0047 0.0257 0.1048
Echinococcus granulosus histone acetyltransferase KAT2B 0.0042 0.0225 0.0622
Trypanosoma cruzi cysteine peptidase, Clan CA, family C54, putative 0.0047 0.0258 0.1053
Toxoplasma gondii Sodium:neurotransmitter symporter family protein 0.0033 0.0158 0.1354
Schistosoma mansoni hypothetical protein 0.0035 0.0173 0.0478
Echinococcus multilocularis Basic leucine zipper (bZIP) transcription 0.0064 0.0377 0.1042
Trichomonas vaginalis heat shock protein, putative 0.004 0.021 0.1217
Loa Loa (eye worm) vesicular acetylcholine transporter unc-17 0.0461 0.3129 0.3129
Echinococcus multilocularis calpain 0.0018 0.0057 0.0157
Echinococcus multilocularis snurportin 1 0.0355 0.2393 0.6617
Brugia malayi Protein kinase domain containing protein 0.0043 0.0232 0.074
Plasmodium vivax protein kinase Crk2 0.0043 0.0232 0.1989
Leishmania major heat shock protein 83-1 0.0047 0.0257 0.1089
Echinococcus multilocularis heat shock protein 90 0.0047 0.0257 0.071
Brugia malayi Sodium:neurotransmitter symporter family protein 0.0033 0.0158 0.0504
Entamoeba histolytica recQ family helicase, putative 0.0013 0.0022 0.0081
Echinococcus multilocularis uncharacterized sodium dependent transporter 0.0033 0.0158 0.0436
Echinococcus granulosus vesicular acetylcholine transporter 0.0461 0.3129 0.8653
Onchocerca volvulus 0.0033 0.0158 0.0087
Loa Loa (eye worm) CMGC/CDK/CDC2 protein kinase 0.0043 0.0232 0.0232
Schistosoma mansoni hypothetical protein 0.0064 0.0377 0.1042
Echinococcus multilocularis vesicular acetylcholine transporter 0.0461 0.3129 0.8653
Toxoplasma gondii cell-cycle-associated protein kinase CDK, putative 0.0043 0.0232 0.1989
Loa Loa (eye worm) serotonin transporter b 0.0033 0.0158 0.0158
Onchocerca volvulus 0.0043 0.0228 0.0158
Trypanosoma cruzi ATP-dependent DEAD/H DNA helicase recQ, putative 0.0013 0.0022 0.0091
Brugia malayi Platelet-activating factor acetylhydrolase, plasma/intracellular isoform II family protein 0.035 0.2356 0.753
Toxoplasma gondii HEAT repeat-containing protein 0.0033 0.0162 0.1387
Brugia malayi Calcitonin receptor-like protein seb-1 0.0251 0.1669 0.5334
Leishmania major geranylgeranyltransferase, putative 0.0022 0.0084 0.0356
Leishmania major myo-inositol-1(or 4)-monophosphatase 1, putative 0.004 0.0209 0.0889
Trypanosoma brucei inositol-1(or 4)-monophosphatase 1, putative 0.004 0.0209 0.0855
Schistosoma mansoni cpg binding protein 0.0092 0.0572 0.1583
Echinococcus multilocularis sodium and chloride dependent glycine 0.0033 0.0158 0.0436
Trypanosoma brucei heat shock protein 90, putative 0.0047 0.0257 0.1048
Leishmania major hypothetical protein, conserved 0.0038 0.0193 0.0819
Plasmodium falciparum ataxin-2 like protein, putative 0.0052 0.0295 0.2531
Echinococcus granulosus histone lysine methyltransferase setb 0.0034 0.0164 0.0453
Toxoplasma gondii histone lysine acetyltransferase GCN5-B 0.0042 0.0225 0.1931
Echinococcus granulosus dynamin 1 0.0024 0.0098 0.027
Brugia malayi Phospholipase A2 family protein 0.0382 0.2581 0.8248
Loa Loa (eye worm) RGC/RGC protein kinase 0.002 0.0071 0.0071
Mycobacterium tuberculosis Probable conserved lipoprotein 0.0038 0.0193 0.1019
Loa Loa (eye worm) hypothetical protein 0.0164 0.107 0.107
Trichomonas vaginalis protein farnesyltransferase beta subunit, putative 0.0022 0.0084 0.047
Toxoplasma gondii PHD-finger domain-containing protein 0.0031 0.0145 0.1242
Trypanosoma brucei dynamin-1-like protein 0.0022 0.0086 0.035
Schistosoma mansoni ap endonuclease 0.002 0.0069 0.0192
Loa Loa (eye worm) hypothetical protein 0.0011 0.0006 0.0006
Schistosoma mansoni ap endonuclease 0.002 0.0069 0.0192
Echinococcus granulosus ATP dependent DNA helicase Q1 0.001 0.0001 0.0004
Trypanosoma brucei calpain-like protein, putative 0.0018 0.0057 0.0232
Echinococcus granulosus dnaJ subfamily B 0.0407 0.2752 0.761
Brugia malayi hypothetical protein 0.0064 0.0377 0.1204
Chlamydia trachomatis Ssodium-dependent amino acid transporter 0.0033 0.0158 0.5
Echinococcus multilocularis gcn5proteinral control of amino acid synthesis 0.0144 0.0931 0.2573
Echinococcus granulosus intermediate filament protein 0.0023 0.0092 0.0255
Entamoeba histolytica Ran family GTPase 0.0024 0.0101 0.0409
Echinococcus multilocularis ATP dependent DNA helicase Q5 0.001 0.0001 0.0004
Schistosoma mansoni DNA helicase recq1 0.001 0.0001 0.0004
Plasmodium falciparum importin beta, putative 0.0033 0.0162 0.1387
Brugia malayi ATP-dependent DNA helicase, RecQ family protein 0.001 0.0001 0.0005
Echinococcus multilocularis GPCR, family 3, C terminal 0.0035 0.0173 0.0478
Leishmania major kinesin, putative 0.0018 0.0057 0.0241
Schistosoma mansoni intermediate filament proteins 0.0023 0.0092 0.0255
Trypanosoma brucei dynamin-1-like protein 0.0022 0.0086 0.035
Mycobacterium ulcerans esterase/lipase LipP 0.0038 0.0193 0.471
Onchocerca volvulus 0.0023 0.0092 0.0021
Trypanosoma cruzi hypothetical protein, conserved 0.0038 0.0193 0.0788
Echinococcus multilocularis ceramide glucosyltransferase 0.023 0.1529 0.4229
Trichomonas vaginalis importin beta-1, putative 0.0027 0.0118 0.0673
Echinococcus multilocularis bloom syndrome protein 0.0025 0.0102 0.0281
Loa Loa (eye worm) GTP-binding regulatory protein Gs alpha-S chain 0.0092 0.0571 0.0571
Plasmodium vivax isocitrate dehydrogenase [NADP], mitochondrial, putative 0.0032 0.0152 0.1307
Plasmodium vivax geranylgeranyl transferase type2 beta subunit, putative 0.0022 0.0084 0.0721
Leishmania major GTP-binding protein, putative 0.0022 0.0086 0.0364
Giardia lamblia PHD finger protein 15 0.0031 0.0145 0.0597
Trichomonas vaginalis Clan CA, family C54, ATG4-like cysteine peptidase 0.0121 0.0769 0.4542
Leishmania major phospholipase A1, putative 0.035 0.2356 1
Echinococcus multilocularis heat shock protein 90 0.004 0.021 0.058
Echinococcus multilocularis survival motor neuron protein 1 0.0244 0.162 0.448
Echinococcus multilocularis cpg binding protein 0.0092 0.0572 0.1583
Echinococcus granulosus dynamin 0.0022 0.0086 0.0237
Loa Loa (eye worm) hypothetical protein 0.0015 0.0035 0.0035
Trichomonas vaginalis Importin beta-1 subunit, putative 0.0027 0.0118 0.0673
Trypanosoma brucei ATP-dependent DEAD/H DNA helicase recQ, putative 0.0013 0.0022 0.0091
Loa Loa (eye worm) hypothetical protein 0.0033 0.0158 0.0158
Brugia malayi MH2 domain containing protein 0.0107 0.0673 0.2152
Trypanosoma brucei GTP-binding nuclear protein rtb2, putative 0.0024 0.0101 0.0411
Loa Loa (eye worm) hypothetical protein 0.0055 0.0313 0.0313
Trichomonas vaginalis geranylgeranyl transferase type II beta subunit, putative 0.0022 0.0084 0.047
Onchocerca volvulus 0.035 0.2356 0.2301
Loa Loa (eye worm) endoplasmin 0.0047 0.0257 0.0257
Echinococcus multilocularis 3 hydroxyacyl coenzyme A dehydrogenase type 2 0.0049 0.0274 0.0758
Trypanosoma cruzi hypothetical protein, conserved 0.0022 0.0084 0.0343
Brugia malayi Hypothetical 52.5 kDa protein ZK945.1 in chromosome II, putative 0.0038 0.0193 0.0617
Brugia malayi vesicular acetylcholine transporter unc-17 0.0461 0.3129 1
Echinococcus granulosus Glutamate receptor ionotropic kainate 2 0.002 0.0071 0.0197
Trypanosoma cruzi AUT2/APG4/ATG4 cysteine peptidase, putative 0.0121 0.0769 0.3141
Trichomonas vaginalis DNA helicase recq1, putative 0.0025 0.0102 0.0575
Toxoplasma gondii dynamin-related protein DRPB 0.0022 0.0086 0.0737
Entamoeba histolytica hypothetical protein 0.0064 0.0377 0.1559
Loa Loa (eye worm) heat shock protein 90 0.0047 0.0257 0.0257
Echinococcus granulosus sodium:chloride dependent neurotransmitter 0.0216 0.1428 0.3949
Loa Loa (eye worm) metabotropic GABA-B receptor subtype 2 0.0055 0.0313 0.0313
Loa Loa (eye worm) hypothetical protein 0.0033 0.0158 0.0158
Loa Loa (eye worm) hypothetical protein 0.0124 0.079 0.079
Loa Loa (eye worm) hypothetical protein 0.0097 0.06 0.06
Schistosoma mansoni histone-lysine n-methyltransferase setb1 0.0034 0.0164 0.0453
Echinococcus granulosus family C2 unassigned peptidase C02 family 0.0064 0.0376 0.1038
Toxoplasma gondii dynamin-related protein DRPA 0.0022 0.0086 0.0737
Leishmania major isocitrate dehydrogenase [NADP], mitochondrial precursor, putative 0.0032 0.0152 0.0646
Trichomonas vaginalis bromodomain-containing protein, putative 0.0042 0.0225 0.1308
Toxoplasma gondii WD domain, G-beta repeat-containing protein 0.001 0.0001 0.0007
Schistosoma mansoni vesicular acetylcholine transporter 0.0461 0.3129 0.8653
Mycobacterium ulcerans lipase LipD 0.0038 0.0193 0.471
Mycobacterium ulcerans aldehyde dehydrogenase 0.0064 0.0373 1
Echinococcus multilocularis hypothetical protein 0.0018 0.0057 0.0157
Loa Loa (eye worm) nucleolar RNA-associated protein alpha 0.0355 0.2393 0.2393
Mycobacterium tuberculosis Probable isocitrate dehydrogenase [NADP] Icd1 (oxalosuccinate decarboxylase) (IDH) (NADP+-specific ICDH) (IDP) 0.0032 0.0152 0.076
Loa Loa (eye worm) hypothetical protein 0.0033 0.0158 0.0158
Loa Loa (eye worm) cytochrome P450 family protein 0.0035 0.0173 0.0173
Schistosoma mansoni metabotropic glutamate receptor 2 3 (mglur group 2) 0.0244 0.1625 0.4494
Trypanosoma cruzi calpain-like cysteine peptidase, putative 0.0018 0.0057 0.0232
Trypanosoma brucei sterol 24-c-methyltransferase, putative 0.0198 0.1304 0.5327
Trypanosoma brucei calpain-like protein, putative 0.0018 0.0057 0.0232
Trypanosoma cruzi isocitrate dehydrogenase [NADP], mitochondrial precursor, putative 0.0032 0.0152 0.0622
Loa Loa (eye worm) hypothetical protein 0.0038 0.0193 0.0193
Schistosoma mansoni calpain-7 (C02 family) 0.0018 0.0057 0.0157
Trichomonas vaginalis chromodomain helicase DNA binding protein, putative 0.002 0.0069 0.0379
Echinococcus granulosus calpain A 0.0018 0.0057 0.0157
Plasmodium falciparum endoplasmin, putative 0.0034 0.0167 0.1436
Mycobacterium tuberculosis Probable hydrolase 0.0038 0.0193 0.1019
Echinococcus multilocularis protein farnesyltransferase subunit beta 0.0022 0.0084 0.0232
Loa Loa (eye worm) hypothetical protein 0.0043 0.0228 0.0228
Onchocerca volvulus 0.035 0.2356 0.2301
Brugia malayi ATP-dependent DNA helicase, RecQ family protein 0.001 0.0001 0.0005
Echinococcus granulosus cysteine protease atg4b 0.0121 0.0769 0.2127
Mycobacterium ulcerans fusion of enoyl-CoA hydratase, EchA21 and lipase, LipE 0.0038 0.0193 0.471
Brugia malayi Guanylyl cyclase protein 23 0.002 0.0071 0.0227
Brugia malayi heat shock protein 90 0.0047 0.0257 0.082
Brugia malayi Pre-SET motif family protein 0.0034 0.0164 0.0524
Schistosoma mansoni metabotropic glutamate receptor 0.018 0.1179 0.3261
Loa Loa (eye worm) inositol-1 0.004 0.0209 0.0209
Plasmodium falciparum protein farnesyltransferase subunit beta 0.0022 0.0084 0.0721
Trypanosoma cruzi heat shock protein 85, putative 0.0047 0.0257 0.1048
Trichomonas vaginalis mgm1, putative 0.0022 0.0086 0.0481
Schistosoma mansoni sodium-dependent neurotransmitter transporter 0.0033 0.0158 0.0436
Trichomonas vaginalis chromodomain helicase DNA binding protein, putative 0.002 0.0069 0.0379
Trypanosoma cruzi heat shock protein 85, putative 0.0047 0.0257 0.1048
Brugia malayi Dynamin central region family protein 0.0022 0.0086 0.0274
Echinococcus granulosus bloom syndrome protein 0.0025 0.0102 0.0281
Echinococcus multilocularis heat shock protein 0.0047 0.0257 0.071
Loa Loa (eye worm) DRP-1 protein 0.0022 0.0086 0.0086
Echinococcus granulosus histone acetyltransferase KAT2B 0.014 0.0903 0.2496
Trichomonas vaginalis cat eye syndrome critical region protein 2, cscr2, putative 0.0042 0.0225 0.1308
Plasmodium falciparum ADP-dependent DNA helicase RecQ 0.0022 0.0081 0.0694
Loa Loa (eye worm) hypothetical protein 0.0038 0.0193 0.0193
Loa Loa (eye worm) hypothetical protein 0.0171 0.1119 0.1119
Trichomonas vaginalis conserved hypothetical protein 0.002 0.0069 0.0379
Mycobacterium leprae conserved hypothetical protein 0.0038 0.0193 0.7856
Trypanosoma cruzi cytochrome P450, putative 0.0015 0.0033 0.0134
Trypanosoma brucei PHD-zinc-finger like domain containing protein, putative 0.001 0.0001 0.0004
Schistosoma mansoni DNA helicase recq5 0.001 0.0001 0.0004
Brugia malayi Cytochrome P450 family protein 0.0015 0.0033 0.0105
Echinococcus granulosus cadherin EGF LAG seven pass G type receptor 0.0079 0.0481 0.133
Leishmania major calpain, putative,cysteine peptidase, Clan CA, family C2, putative 0.0018 0.0057 0.0241
Echinococcus multilocularis cysteine protease atg4b 0.0121 0.0769 0.2127
Echinococcus granulosus Basic leucine zipper bZIP transcription 0.0064 0.0377 0.1042
Echinococcus multilocularis lysine specific demethylase 5A 0.0037 0.019 0.0524
Plasmodium vivax histone acetyltransferase GCN5, putative 0.0042 0.0225 0.1931
Schistosoma mansoni sodium/chloride dependent neurotransmitter transporter 0.0216 0.1428 0.3949
Brugia malayi hypothetical protein 0.0034 0.0166 0.053
Onchocerca volvulus 0.0088 0.0538 0.047
Trichomonas vaginalis myo inositol monophosphatase, putative 0.004 0.0209 0.1216
Leishmania major extracellular receptor, putative 0.002 0.0071 0.0302
Toxoplasma gondii Sodium:neurotransmitter symporter family protein 0.0033 0.0158 0.1354
Echinococcus multilocularis family C2 unassigned peptidase (C02 family) 0.0064 0.0376 0.1038
Echinococcus multilocularis Glutamate receptor, ionotropic kainate 2 0.002 0.0071 0.0197
Schistosoma mansoni dynamin 0.0024 0.0098 0.027
Echinococcus granulosus cytoplasmic intermediate filament protein 0.0011 0.0009 0.0025
Schistosoma mansoni mixed-lineage leukemia protein mll 0.0187 0.1226 0.3391
Loa Loa (eye worm) hypothetical protein 0.0033 0.0158 0.0158
Onchocerca volvulus Poor gastrulation protein homolog 0.0035 0.0173 0.0102
Brugia malayi GTP-binding regulatory protein Gs alpha-S chain, putative 0.0092 0.0571 0.1824
Echinococcus multilocularis sodium dependent neurotransmitter transporter 0.0033 0.0158 0.0436
Trichomonas vaginalis conserved hypothetical protein 0.002 0.0069 0.0379
Trichomonas vaginalis Clan CA, family C54, ATG4-like cysteine peptidase 0.0121 0.0769 0.4542
Brugia malayi Hsp90 protein 0.0031 0.0147 0.0471
Echinococcus multilocularis dnaJ subfamily B 0.0407 0.2752 0.761
Loa Loa (eye worm) hypothetical protein 0.0022 0.0084 0.0084
Echinococcus granulosus inositol monophosphatase 1 0.004 0.0209 0.0579
Loa Loa (eye worm) platelet-activating factor acetylhydrolase 0.035 0.2356 0.2356
Trichomonas vaginalis protein farnesyltransferase beta subunit, putative 0.0022 0.0084 0.047
Loa Loa (eye worm) hypothetical protein 0.002 0.0071 0.0071
Echinococcus multilocularis lamin 0.0023 0.0092 0.0255
Trypanosoma cruzi heat shock protein 90, putative 0.002 0.0067 0.0275
Leishmania major 3-oxoacyl-(acyl-carrier protein) reductase, putative 0.0049 0.0274 0.1163
Echinococcus multilocularis dynamin 1 protein 0.0022 0.0086 0.0237
Echinococcus granulosus snurportin 1 0.0355 0.2393 0.6617
Echinococcus granulosus importin subunit beta 1 0.0033 0.0162 0.0447
Schistosoma mansoni geranylgeranyl transferase type I beta subunit 0.0022 0.0084 0.0232
Brugia malayi cytoplasmic intermediate filament protein 0.0012 0.0017 0.0056
Toxoplasma gondii ATP-dependent DNA helicase, RecQ family protein 0.001 0.0001 0.0013
Brugia malayi Cytochrome P450 family protein 0.0035 0.0173 0.0554
Echinococcus multilocularis receptor type guanylyl cyclase 0.002 0.0071 0.0197
Echinococcus multilocularis NADP dependent isocitrate dehydrogenase 0.0032 0.0152 0.0421
Trichomonas vaginalis dynamin, putative 0.0022 0.0086 0.0481
Trypanosoma brucei phospholipase A1, putative 0.035 0.2356 0.9622
Echinococcus multilocularis DNA (apurinic or apyrimidinic site) lyase 0.002 0.0069 0.0192
Trichomonas vaginalis set domain proteins, putative 0.0253 0.1687 1
Trichomonas vaginalis Clan CA, family C54, ATG4-like cysteine peptidase 0.0121 0.0769 0.4542
Trichomonas vaginalis CMGC family protein kinase 0.0043 0.0232 0.1348
Trypanosoma cruzi AUT2/APG4/ATG4 cysteine peptidase, putative 0.0047 0.0258 0.1053
Entamoeba histolytica Rad52/22 family double-strand break repair protein, putative 0.0101 0.0634 0.2632
Trypanosoma cruzi myo-inositol-1(or 4)-monophosphatase 1, putative 0.004 0.0209 0.0855
Loa Loa (eye worm) hypothetical protein 0.0033 0.0158 0.0158
Echinococcus granulosus atrial natriuretic peptide receptor 0.002 0.0071 0.0197
Trypanosoma cruzi myo-inositol-1(or 4)-monophosphatase 1, putative 0.004 0.0209 0.0855
Echinococcus granulosus ATP dependent DNA helicase Q5 0.001 0.0001 0.0004
Plasmodium falciparum heat shock protein 90 0.0047 0.0257 0.2203
Giardia lamblia Grp94/Hsp90 0.0044 0.0237 0.098
Schistosoma mansoni sodium/chloride dependent transporter 0.0033 0.0158 0.0436
Trypanosoma brucei cysteine peptidase, Clan CA, family C54, putative 0.0047 0.0258 0.1053
Loa Loa (eye worm) hypothetical protein 0.0011 0.0009 0.0009
Leishmania major heat shock protein 83-1 0.0047 0.0257 0.1089
Brugia malayi hypothetical protein 0.0164 0.107 0.3419
Brugia malayi Corticotropin releasing factor receptor 2 precursor, putative 0.0251 0.1669 0.5334
Echinococcus granulosus jumonji domain containing protein 0.0043 0.0228 0.0631
Echinococcus multilocularis calpain 5 0.0018 0.0057 0.0157
Toxoplasma gondii heat shock protein 75, putative 0.0031 0.0147 0.1265
Trypanosoma cruzi sterol 24-c-methyltransferase, putative 0.0198 0.1304 0.5327
Loa Loa (eye worm) hypothetical protein 0.0034 0.0164 0.0164
Toxoplasma gondii prenyltransferase and squalene oxidase repeat-containing protein 0.0022 0.0084 0.0721
Mycobacterium tuberculosis Conserved protein 0.0038 0.0193 0.1019
Echinococcus granulosus diuretic hormone 44 receptor GPRdih2 0.0079 0.0481 0.133
Mycobacterium tuberculosis Possible penicillin-binding protein 0.0241 0.1604 1
Leishmania major calpain-like cysteine peptidase, putative,cysteine peptidase, Clan CA, family C2, putative 0.0018 0.0057 0.0241
Echinococcus granulosus protein farnesyltransferase subunit beta 0.0022 0.0084 0.0232
Echinococcus multilocularis guanine nucleotide binding protein G(s) subunit 0.0092 0.0571 0.1578
Echinococcus granulosus survival motor neuron protein 1 0.0244 0.162 0.448
Schistosoma mansoni endoplasmin 0.0047 0.0257 0.071
Loa Loa (eye worm) Sodium:neurotransmitter symporter family protein 0.0033 0.0158 0.0158
Giardia lamblia Kinase, CMGC CDK 0.0043 0.0232 0.0959
Echinococcus granulosus 5'partial|cyclin dependent kinase 1 0.0043 0.0232 0.0641
Onchocerca volvulus 0.0034 0.0164 0.0094
Loa Loa (eye worm) MH2 domain-containing protein 0.0107 0.0673 0.0673
Echinococcus multilocularis diuretic hormone 44 receptor GPRdih2 0.0079 0.0481 0.133
Trypanosoma brucei heat shock protein, putative 0.0047 0.0257 0.1048
Trichomonas vaginalis geranylgeranyl transferase type II beta subunit, putative 0.0022 0.0084 0.047
Echinococcus multilocularis aldehyde dehydrogenase, mitochondrial 0.0064 0.0373 0.1031
Plasmodium vivax heat shock protein, putative 0.0178 0.1165 1
Echinococcus multilocularis histone lysine methyltransferase setb histone lysine methyltransferase eggless 0.0034 0.0164 0.0453
Brugia malayi Peptidase family C54 containing protein 0.0121 0.0769 0.2458
Echinococcus multilocularis neuropeptide receptor A26 0.0401 0.2715 0.7508
Echinococcus granulosus neuropeptide receptor A26 0.0401 0.2715 0.7508
Brugia malayi exodeoxyribonuclease III family protein 0.002 0.0069 0.0222
Loa Loa (eye worm) prenyltransferase and squalene oxidase repeat family protein 0.0022 0.0084 0.0084
Entamoeba histolytica 90 kDa heat shock protein, putative 0.0031 0.0147 0.0603
Loa Loa (eye worm) CMGC/CDK/CDK5 protein kinase 0.0043 0.0232 0.0232
Trypanosoma cruzi cdc2-related kinase 1 0.0043 0.0232 0.0946
Leishmania major farnesyltransferase beta subunit 0.0022 0.0084 0.0356
Schistosoma mansoni myst-related protein 0.001 0.0003 0.0007
Echinococcus multilocularis guanine nucleotide binding protein G(s) subunit 0.0092 0.0571 0.1578
Leishmania major cytochrome p450-like protein 0.0015 0.0033 0.0139
Onchocerca volvulus 0.0023 0.0092 0.0021
Schistosoma mansoni hypothetical protein 0.0079 0.0481 0.133
Entamoeba histolytica heat shock protein 90, putative 0.0047 0.0257 0.1059
Loa Loa (eye worm) cytochrome P450 family protein 0.0015 0.0033 0.0033
Echinococcus multilocularis histone lysine N methyltransferase MLL3 0.0028 0.0127 0.0351
Trichomonas vaginalis chromodomain helicase DNA binding protein, putative 0.002 0.0069 0.0379
Brugia malayi hypothetical protein 0.0052 0.0295 0.0942
Brugia malayi Latrophilin receptor protein 2 0.0079 0.0481 0.1537
Echinococcus granulosus glutamate receptor ionotrophic AMPA 3 0.002 0.0071 0.0197
Schistosoma mansoni ran 0.0024 0.0101 0.0279
Mycobacterium tuberculosis Probable lipase LipE 0.0038 0.0193 0.1019
Brugia malayi GTP-binding nuclear protein RAN/TC4 0.0024 0.0101 0.0322
Plasmodium falciparum dynamin-like protein 0.0022 0.0086 0.0737
Toxoplasma gondii histone lysine methyltransferase SET/SUV39 0.0034 0.0164 0.1408
Trichomonas vaginalis ap endonuclease, putative 0.002 0.0069 0.0384
Loa Loa (eye worm) acetyltransferase 0.0144 0.0931 0.0931
Onchocerca volvulus 0.0038 0.0193 0.0123
Trypanosoma cruzi heat shock protein 85, putative 0.004 0.021 0.0856
Schistosoma mansoni norepinephrine/norepinephrine transporter 0.0033 0.0158 0.0436
Mycobacterium ulcerans hypothetical protein 0.0038 0.0193 0.471
Onchocerca volvulus 0.0038 0.0193 0.0123
Giardia lamblia GTP-binding nuclear protein RAN/TC4 0.0024 0.0101 0.0414
Onchocerca volvulus 0.0033 0.0158 0.0087
Echinococcus multilocularis sodium:chloride dependent neurotransmitter 0.0216 0.1428 0.3949
Echinococcus multilocularis sodium and chloride dependent glycine 0.0033 0.0158 0.0436
Toxoplasma gondii Hsp90 domain-containing protein 0.0178 0.1165 1
Brugia malayi 3-hydroxyacyl-CoA dehydrogenase type II 0.0049 0.0274 0.0876
Echinococcus multilocularis NADP dependent isocitrate dehydrogenase 0.0032 0.0152 0.0421
Echinococcus granulosus glutamate receptor 2 0.002 0.0071 0.0197
Brugia malayi Endoplasmin precursor 0.0047 0.0257 0.082
Schistosoma mansoni family C54 unassigned peptidase (C54 family) 0.0121 0.0769 0.2127
Plasmodium falciparum ATP-dependent DNA helicase Q1 0.001 0.0001 0.0013
Entamoeba histolytica cell division protein kinase 2, putative 0.0043 0.0232 0.0955
Trypanosoma cruzi calpain-like cysteine peptidase, putative 0.0018 0.0057 0.0232
Onchocerca volvulus Metabotropic glutamate receptor homolog 0.0035 0.0173 0.0102
Echinococcus multilocularis peregrin 0.0034 0.0169 0.0468
Echinococcus granulosus lysine specific demethylase 5A 0.0042 0.0224 0.062
Plasmodium vivax dynamin protein, putative 0.0022 0.0086 0.0737
Loa Loa (eye worm) hypothetical protein 0.0043 0.0228 0.0228
Echinococcus granulosus sodium dependent neurotransmitter transporter 0.0033 0.0158 0.0436
Trypanosoma cruzi cytochrome P450, putative 0.0015 0.0033 0.0134
Brugia malayi cell division control protein 2 homolog 0.0043 0.0232 0.074
Brugia malayi calpain family protein 1 0.0061 0.0354 0.1131
Loa Loa (eye worm) hypothetical protein 0.0123 0.0785 0.0785
Mycobacterium tuberculosis Conserved protein 0.0038 0.0193 0.1019
Giardia lamblia Heat shock protein HSP 90-alpha 0.004 0.021 0.0867
Echinococcus granulosus geminin 0.0531 0.3616 1
Trichomonas vaginalis penicillin-binding protein, putative 0.0038 0.0193 0.1118
Schistosoma mansoni Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) 0.0092 0.0571 0.1578
Onchocerca volvulus 0.005 0.0276 0.0206
Echinococcus multilocularis Glutamate receptor, ionotropic kainate 2 0.002 0.0071 0.0197
Loa Loa (eye worm) hypothetical protein 0.0023 0.0089 0.0089
Mycobacterium ulcerans short-chain type dehydrogenase/reductase 0.0049 0.0274 0.7097
Schistosoma mansoni ceramide glucosyltransferase 0.023 0.1529 0.4229
Trichomonas vaginalis D-aminoacylase, putative 0.0038 0.0193 0.1118
Trichomonas vaginalis geranylgeranyl transferase type I beta subunit, putative 0.0022 0.0084 0.047
Plasmodium falciparum heat shock protein 90, putative 0.0178 0.1165 1
Schistosoma mansoni hypothetical protein 0.0355 0.2393 0.6617
Brugia malayi jmjC domain containing protein 0.0101 0.0631 0.2016
Wolbachia endosymbiont of Brugia malayi fructose-1,6-bisphosphatase 0.004 0.0209 0.8373
Echinococcus multilocularis atrial natriuretic peptide receptor 0.002 0.0071 0.0197
Trichomonas vaginalis chromodomain-helicase-DNA-binding protein, putative 0.002 0.0069 0.0379
Schistosoma mansoni tar DNA-binding protein 0.013 0.0831 0.2299
Echinococcus granulosus heat shock protein 90 0.0047 0.0257 0.071
Trichomonas vaginalis ran, putative 0.0024 0.0101 0.057
Toxoplasma gondii GTP-binding nuclear protein ran/tc4 0.0024 0.0101 0.0865
Plasmodium vivax farnesyltransferase beta subunit, putative 0.0022 0.0084 0.0721
Trypanosoma cruzi sterol 24-c-methyltransferase, putative 0.0198 0.1304 0.5327
Giardia lamblia Rab geranylgeranyltransferase 0.0022 0.0084 0.0344
Onchocerca volvulus Alhambra homolog 0.0031 0.0145 0.0074
Echinococcus granulosus calpain 0.0018 0.0057 0.0157
Echinococcus multilocularis cyclin dependent kinase 0.0043 0.0232 0.0641
Schistosoma mansoni lamin 0.0023 0.0092 0.0255
Echinococcus multilocularis cyclin dependent kinase 5 activator 1 0.0257 0.1714 0.474
Schistosoma mansoni 3-hydroxyacyl-CoA dehydrogenase 0.0049 0.0274 0.0758
Schistosoma mansoni hypothetical protein 0.0031 0.0145 0.04
Echinococcus granulosus nmda type glutamate receptor 0.002 0.0071 0.0197
Onchocerca volvulus 0.0033 0.0158 0.0087
Schistosoma mansoni tar DNA-binding protein 0.013 0.0831 0.2299
Loa Loa (eye worm) hypothetical protein 0.002 0.0071 0.0071
Trypanosoma cruzi phospholipase A2-like protein, putative 0.016 0.1043 0.426
Plasmodium falciparum cysteine protease ATG4, putative 0.0047 0.0258 0.2214
Schistosoma mansoni glutamate receptor NMDA 0.002 0.0071 0.0197
Brugia malayi Cytochrome P450 family protein 0.0015 0.0033 0.0105
Loa Loa (eye worm) cytoplasmic intermediate filament protein 0.0012 0.0017 0.0017
Echinococcus multilocularis ATP dependent DNA helicase Q1 0.001 0.0001 0.0004
Brugia malayi RNA recognition motif domain containing protein 0.013 0.0831 0.2657
Onchocerca volvulus Heat shock protein 75 kDa, mitochondrial homolog 0.0031 0.0147 0.0077
Echinococcus granulosus guanine nucleotide binding protein Gs subunit 0.0092 0.0571 0.1578
Mycobacterium tuberculosis Halimadienyl diphosphate synthase 0.0223 0.148 0.9213
Mycobacterium ulcerans aldehyde dehydrogenase 0.0064 0.0373 1
Brugia malayi jmjC domain containing protein 0.0042 0.0224 0.0717
Loa Loa (eye worm) hypothetical protein 0.0121 0.0769 0.0769
Echinococcus multilocularis cyclin dependent kinase 5 0.0043 0.0232 0.0641
Schistosoma mansoni sodium/chloride dependent transporter 0.0033 0.0158 0.0436
Mycobacterium ulcerans beta-lactamase 0.0038 0.0193 0.471
Trichomonas vaginalis DNA helicase recq, putative 0.0013 0.0022 0.0103
Trichomonas vaginalis heat shock protein, putative 0.0044 0.0237 0.1378
Echinococcus granulosus NADP dependent isocitrate dehydrogenase 0.0032 0.0152 0.0421
Schistosoma mansoni geranylgeranyl transferase type I beta subunit 0.0022 0.0084 0.0232
Loa Loa (eye worm) hypothetical protein 0.0216 0.1428 0.1428
Schistosoma mansoni sodium-dependent amino acid transporter 0.0033 0.0158 0.0436
Plasmodium falciparum amino acid transporter, putative 0.0033 0.0158 0.1354
Schistosoma mansoni survival motor neuron protein 0.005 0.0276 0.0762
Schistosoma mansoni serine/threonine protein kinase 0.0043 0.0232 0.0641
Schistosoma mansoni ceramide glucosyltransferase 0.023 0.1529 0.4229
Loa Loa (eye worm) PHD-finger family protein 0.0031 0.0145 0.0145
Trypanosoma cruzi dynamin-1-like protein 0.0022 0.0086 0.035
Loa Loa (eye worm) TAR-binding protein 0.013 0.0831 0.0831
Mycobacterium tuberculosis Conserved protein 0.0038 0.0193 0.1019
Trypanosoma brucei heat shock protein, putative 0.0047 0.0257 0.1048
Loa Loa (eye worm) latrophilin receptor protein 2 0.0079 0.0481 0.0481
Echinococcus multilocularis tar DNA binding protein 0.013 0.0831 0.2299
Brugia malayi Bloom's syndrome protein homolog 0.0025 0.0102 0.0325
Echinococcus multilocularis metabotropic glutamate receptor 2 0.018 0.1179 0.3261
Schistosoma mansoni bromodomain-containing nuclear protein 1 brd1 0.0031 0.0145 0.04

Activities

Activity type Activity value Assay description Source Reference
Chemotactic index (functional) = 0.84 Chemotactic activity of compound measured as function of concentration of 10 uM compared to peptide T,[DA1a]peptide T and amygdalin ChEMBL. 15713414

Phenotypes

Whole-cell/tissue/organism interactions

We have no records of whole-cell/tissue assays done with this compound What does this mean?

Many chemical entities in TDR Targets come from high-throughput screenings with whole cells or tissue samples, and not all assayed compounds have been tested against a single a single target protein, probably because they get ruled out during screening process. Even if these compounds may have not been of interest in the original screening, they may come as interesting leads for other screening assays. Furthermore, we may be able to propose drug-target associations using chemical similarities and network patterns.

Annotated phenotypes:

We have no manually annotated phenotypes for this drug. What does this mean? / Care to help?
In TDR Targets, information about phenotypes that are caused by drugs, or by genetic manipulation of cells (e.g. gene knockouts or knockdowns) is manually curated from the literature. These descriptions help to describe the potential of the target for drug development. If no information is available for this gene or if the information is incomplete, this may mean that i) the papers containing this information either appeared after the curation effort for this organism was carried out or they were inadvertently missed by curators; or that ii) the curation effort for this organism has not yet started.
 
In any case, if you have information about papers containing relevant validation data for this target, please log in using your TDR Targets username and password and send them to us using the corresponding form in this page (only visible to registered users) or contact us.

External resources for this compound

Bibliographic References

1 literature reference was collected for this gene.

If you have references for this compound, please enter them in a user comment (below) or Contact us.