Detailed information for compound 31521

Basic information

Technical information
  • Name: Unnamed compound
  • MW: 335.236 | Formula: C17H19BrO2
  • H donors: 2 H acceptors: 2 LogP: 4.85 Rotable bonds: 5
    Rule of 5 violations (Lipinski): 1
  • SMILES: CC[C@@H]([C@H](c1ccc(cc1)O)CBr)c1ccc(cc1)O
  • InChi: 1S/C17H19BrO2/c1-2-16(12-3-7-14(19)8-4-12)17(11-18)13-5-9-15(20)10-6-13/h3-10,16-17,19-20H,2,11H2,1H3/t16-,17+/m1/s1
  • InChiKey: DXBQUTUBYLSLOU-SJORKVTESA-N  


Substructure search Similarity search

Network

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Synonyms

No synonyms found for this compound

Targets

Known targets for this compound

No curated genes were found associated with this compound

Predicted pathogen targets for this compound

By orthology
No druggable targets predicted by orthology data
By sequence similarity to non orthologous known druggable targets
No druggable targets predicted by sequence similarity
Obtained from network model

Ranking Plot

Putative Targets List

Species Potential target Raw Global Species
Echinococcus multilocularis neuropeptide Y receptor 0.0033 0.0328 0.0394
Brugia malayi Nuclear hormone receptor E75 0.0148 0.2606 0.2603
Echinococcus multilocularis Nuclear hormone receptor HR96 0.0148 0.2606 0.3224
Mycobacterium tuberculosis Probable oxidoreductase 0.0118 0.2015 0.2259
Onchocerca volvulus 0.0073 0.1113 0.1188
Echinococcus multilocularis nuclear receptor 2DBD gamma 0.0313 0.5894 0.7309
Mycobacterium ulcerans cytochrome P450 188A3 Cyp188A3 0.0034 0.0345 0.0669
Trichomonas vaginalis adenylate cyclase, putative 0.0026 0.0184 0.0187
Brugia malayi Sodium:neurotransmitter symporter family protein 0.0261 0.4864 0.4862
Toxoplasma gondii pyruvate kinase PyK1 0.007 0.1073 0.7442
Brugia malayi Nuclear hormone receptor family member nhr-14 0.0313 0.5894 0.5892
Mycobacterium tuberculosis Dihydrolipoamide dehydrogenase LpdC (lipoamide reductase (NADH)) (lipoyl dehydrogenase) (dihydrolipoyl dehydrogenase) (diaphoras 0.0118 0.2015 0.2259
Onchocerca volvulus 0.0033 0.0328 0.0343
Brugia malayi Sodium:neurotransmitter symporter family protein 0.0044 0.0552 0.0548
Echinococcus multilocularis neuropeptide Y receptor 0.0033 0.0328 0.0394
Loa Loa (eye worm) latrophilin receptor protein 2 0.0032 0.0302 0.0299
Schistosoma mansoni hypothetical protein 0.0069 0.1036 0.1285
Schistosoma mansoni hypothetical protein 0.0032 0.0302 0.0375
Echinococcus granulosus g-protein coupled receptor 0.0033 0.0328 0.0394
Brugia malayi Nuclear hormone receptor family member nhr-19 0.0313 0.5894 0.5892
Loa Loa (eye worm) gonadotropin-releasing hormone receptor 2 0.0033 0.0328 0.0325
Brugia malayi beta-lactamase family protein 0.0073 0.1113 0.1109
Schistosoma mansoni Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) 0.0051 0.068 0.0843
Loa Loa (eye worm) nuclear hormone receptor family member nhr-41 0.0313 0.5894 0.5892
Schistosoma mansoni histone-lysine n-methyltransferase suv9 0.0062 0.0895 0.111
Loa Loa (eye worm) hypothetical protein 0.0033 0.0328 0.0325
Mycobacterium tuberculosis Probable cytochrome P450 139 Cyp139 0.0034 0.0345 0.0378
Schistosoma mansoni gabp alpha 0.0077 0.1203 0.1492
Schistosoma mansoni amine GPCR 0.0033 0.0328 0.0407
Loa Loa (eye worm) nuclear receptor NHR-67 0.0148 0.2606 0.2604
Mycobacterium ulcerans carbon monoxide dehydrogenase 0.0124 0.2136 0.4246
Echinococcus multilocularis endonuclease exonuclease phosphatase 0.0189 0.3434 0.4253
Loa Loa (eye worm) aryl Hydrocarbon receptor Associated protein family member 0.0026 0.0184 0.018
Brugia malayi nuclear hormone receptor 0.0148 0.2606 0.2603
Mycobacterium tuberculosis Conserved protein 0.0073 0.1113 0.1243
Echinococcus multilocularis Polycystic kidney disease protein 0.0084 0.1338 0.1648
Echinococcus granulosus neuropeptide receptor 0.0033 0.0328 0.0394
Mycobacterium ulcerans pyruvate kinase 0.007 0.1073 0.2124
Echinococcus multilocularis g protein coupled receptor 0.0033 0.0328 0.0394
Brugia malayi ecdysone receptor 0.0148 0.2606 0.2603
Brugia malayi Pyruvate kinase, alpha/beta domain containing protein 0.0021 0.0095 0.0091
Brugia malayi Nuclear hormone receptor family member nhr-25 0.0313 0.5894 0.5892
Entamoeba histolytica pyruvate kinase, putative 0.0049 0.0649 0.3965
Mycobacterium tuberculosis Probable carbon monoxyde dehydrogenase (large chain) 0.0088 0.1425 0.1594
Mycobacterium tuberculosis Probable aldehyde dehydrogenase 0.0064 0.0947 0.1056
Loa Loa (eye worm) hypothetical protein 0.0069 0.1036 0.1033
Mycobacterium ulcerans cytochrome P450 187A5 Cyp187A5 0.0034 0.0345 0.0669
Echinococcus granulosus Polycystic kidney disease protein 0.0084 0.1338 0.1648
Echinococcus granulosus rhodopsin orphan GPCR 0.0033 0.0328 0.0394
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0033 0.0328 0.0407
Schistosoma mansoni scm-relatedprotein containing 4 mbt domains (sfmbt) 0.0048 0.0626 0.0776
Schistosoma mansoni norepinephrine/norepinephrine transporter 0.0261 0.4864 0.6035
Mycobacterium ulcerans cytochrome P450 143A3 Cyp143A3 0.0034 0.0345 0.0669
Brugia malayi hypothetical protein 0.0165 0.2958 0.2955
Brugia malayi hypothetical protein 0.0148 0.2606 0.2603
Brugia malayi Pyruvate kinase, M2 isozyme 0.007 0.1073 0.1069
Mycobacterium ulcerans fusion of enoyl-CoA hydratase, EchA21 and lipase, LipE 0.0073 0.1113 0.2204
Brugia malayi laminin-like protein K08C7.3 precursor 0.0026 0.0187 0.0183
Loa Loa (eye worm) hypothetical protein 0.0033 0.0328 0.0325
Brugia malayi Doublecortin family protein 0.0084 0.1338 0.1334
Brugia malayi Sodium:neurotransmitter symporter family protein 0.0044 0.0552 0.0548
Schistosoma mansoni hypothetical protein 0.0074 0.1136 0.141
Brugia malayi hypoxia-induced factor 1 0.0307 0.578 0.5779
Mycobacterium tuberculosis Probable reductase 0.0106 0.178 0.1994
Brugia malayi hypothetical protein 0.0033 0.0328 0.0324
Schistosoma mansoni hypothetical protein 0.0175 0.3146 0.3903
Leishmania major tyrosyl-DNA phosphodiesterase 1 0.0065 0.0961 0.8369
Schistosoma mansoni neuropeptide receptor 0.0033 0.0328 0.0407
Echinococcus multilocularis suppression of tumorigenicity 18 protein 0.0055 0.0758 0.0928
Echinococcus granulosus pyruvate kinase 0.0036 0.039 0.0472
Schistosoma mansoni retinoid-x-receptor (RXR) 0.0165 0.2958 0.367
Trichomonas vaginalis conserved hypothetical protein 0.0026 0.0184 0.0187
Brugia malayi G-protein coupled receptor 0.0033 0.0328 0.0324
Schistosoma mansoni retinoid-x-receptor (RXR) 0.0313 0.5894 0.7312
Loa Loa (eye worm) unidentified vitellogenin-linked transcript protein 6 0.0033 0.0328 0.0325
Loa Loa (eye worm) hypothetical protein 0.0044 0.0552 0.0549
Loa Loa (eye worm) hypothetical protein 0.0033 0.0328 0.0325
Mycobacterium tuberculosis NADPH-dependent mycothiol reductase Mtr 0.0046 0.0595 0.0659
Brugia malayi nuclear hormone receptor family member nhr-6 0.0148 0.2606 0.2603
Mycobacterium ulcerans aldehyde dehydrogenase 0.0064 0.0947 0.1872
Mycobacterium tuberculosis Probable cytochrome P450 144 Cyp144 0.0034 0.0345 0.0378
Loa Loa (eye worm) hypothetical protein 0.0148 0.2606 0.2604
Mycobacterium tuberculosis Probable esterase/lipase LipP 0.0073 0.1113 0.1243
Loa Loa (eye worm) hypothetical protein 0.0148 0.2606 0.2604
Mycobacterium ulcerans cytochrome P450 142A3 Cyp142A3 0.0034 0.0345 0.0669
Trichomonas vaginalis D-aminoacylase, putative 0.0073 0.1113 0.1188
Toxoplasma gondii cytochrome p450 superfamily protein 0.0034 0.0345 0.1323
Brugia malayi nuclear receptor NHR-88 0.0313 0.5894 0.5892
Echinococcus multilocularis fmrfamide receptor 0.0033 0.0328 0.0394
Echinococcus multilocularis nuclear receptor subfamily 1 group D 0.0165 0.2958 0.3662
Echinococcus granulosus polycomb protein SCMH1 0.0048 0.0626 0.0764
Trichomonas vaginalis pyruvate kinase, putative 0.007 0.1073 0.1145
Echinococcus multilocularis tm gpcr rhodopsin gpcr rhodopsin superfamily 0.0033 0.0328 0.0394
Echinococcus granulosus pyruvate kinase 0.007 0.1073 0.132
Echinococcus multilocularis aldehyde dehydrogenase, mitochondrial 0.0064 0.0947 0.1163
Brugia malayi bHLH-PAS transcription factor 0.0073 0.1132 0.1128
Giardia lamblia Pyruvate kinase 0.0036 0.039 0.358
Loa Loa (eye worm) pre-SET domain-containing protein family protein 0.0425 0.8129 0.8128
Echinococcus granulosus bloom syndrome protein 0.0021 0.0088 0.0096
Mycobacterium tuberculosis Probable lipase LipD 0.0073 0.1113 0.1243
Loa Loa (eye worm) hypothetical protein 0.0017 0.001 0.0006
Echinococcus granulosus allatostatin A receptor 0.0033 0.0328 0.0394
Echinococcus granulosus serotonin receptor 0.0033 0.0328 0.0394
Mycobacterium leprae Probable lipase LipE 0.0073 0.1113 0.5075
Loa Loa (eye worm) beta-lactamase 0.0073 0.1113 0.111
Mycobacterium tuberculosis Probable pyruvate kinase PykA 0.007 0.1073 0.1198
Echinococcus multilocularis pyruvate kinase 0.0036 0.039 0.0472
Toxoplasma gondii thioredoxin reductase 0.0046 0.0595 0.3426
Loa Loa (eye worm) pigment dispersing factor receptor c 0.01 0.1668 0.1665
Loa Loa (eye worm) hypothetical protein 0.0033 0.0328 0.0325
Echinococcus multilocularis FTZ F1 alpha 0.0313 0.5894 0.7309
Loa Loa (eye worm) hypothetical protein 0.0073 0.1113 0.111
Loa Loa (eye worm) thioredoxin reductase 0.0046 0.0595 0.0592
Toxoplasma gondii Sodium:neurotransmitter symporter family protein 0.0044 0.0552 0.3064
Trypanosoma cruzi hypothetical protein, conserved 0.0073 0.1113 1
Loa Loa (eye worm) CXXC zinc finger family protein 0.003 0.026 0.0256
Echinococcus multilocularis fmrfamide receptor 0.0033 0.0328 0.0394
Echinococcus granulosus neuropeptide s receptor 0.0033 0.0328 0.0394
Onchocerca volvulus Bile acid receptor homolog 0.0313 0.5894 0.6336
Brugia malayi Ligand-binding domain of nuclear hormone receptor family protein 0.0313 0.5894 0.5892
Loa Loa (eye worm) hypothetical protein 0.0148 0.2606 0.2604
Plasmodium vivax multidomain scavenger receptor, putative 0.0084 0.1338 1
Loa Loa (eye worm) hypothetical protein 0.0313 0.5894 0.5892
Echinococcus multilocularis alpha 1A adrenergic receptor 0.0033 0.0328 0.0394
Loa Loa (eye worm) nuclear hormone receptor family member nhr-40 0.0313 0.5894 0.5892
Brugia malayi Nuclear hormone receptor family member nhr-31 0.0313 0.5894 0.5892
Schistosoma mansoni neuropeptide F-like receptor 0.0033 0.0328 0.0407
Onchocerca volvulus 0.0148 0.2606 0.2796
Schistosoma mansoni amine GPCR 0.0033 0.0328 0.0407
Loa Loa (eye worm) cytochrome P450 0.0034 0.0345 0.0342
Onchocerca volvulus Nuclear receptor subfamily 6 group A member 1 homolog 0.0148 0.2606 0.2796
Schistosoma mansoni ancient conserved domain protein 2 (cyclin m2) 0.0033 0.0328 0.0407
Toxoplasma gondii hypothetical protein 0.0044 0.0552 0.3064
Schistosoma mansoni laminin gamma-3 chain 0.0026 0.0187 0.0232
Brugia malayi mbt repeat family protein 0.0048 0.0626 0.0622
Loa Loa (eye worm) nuclear hormone receptor family member nhr-49 0.0313 0.5894 0.5892
Brugia malayi MH2 domain containing protein 0.0123 0.2119 0.2116
Loa Loa (eye worm) hypothetical protein 0.0033 0.0328 0.0325
Schistosoma mansoni sodium/chloride dependent neurotransmitter transporter 0.0044 0.0552 0.0685
Onchocerca volvulus 0.0313 0.5894 0.6336
Brugia malayi orphan nuclear receptor NR2E1 0.0148 0.2606 0.2603
Echinococcus granulosus tar DNA binding protein 0.0067 0.1011 0.1242
Loa Loa (eye worm) transcription factor SMAD2 0.0123 0.2119 0.2117
Onchocerca volvulus 0.0033 0.0328 0.0343
Onchocerca volvulus 0.0044 0.0552 0.0584
Brugia malayi hypothetical protein 0.0165 0.2958 0.2955
Loa Loa (eye worm) hypothetical protein 0.0033 0.0328 0.0325
Schistosoma mansoni cpg binding protein 0.003 0.026 0.0322
Brugia malayi EGF-like domain containing protein 0.0026 0.0187 0.0183
Loa Loa (eye worm) hypothetical protein 0.0033 0.0328 0.0325
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0033 0.0328 0.0407
Schistosoma mansoni sodium/chloride dependent neurotransmitter transporter 0.0044 0.0552 0.0685
Onchocerca volvulus 0.0033 0.0328 0.0343
Echinococcus multilocularis lysine specific demethylase 5A 0.0058 0.0821 0.1006
Trichomonas vaginalis set domain proteins, putative 0.0484 0.9296 1
Echinococcus multilocularis nuclear receptor nhr 48 0.0148 0.2606 0.3224
Loa Loa (eye worm) hypothetical protein 0.0033 0.0328 0.0325
Echinococcus multilocularis pikachurin 0.0026 0.0187 0.0219
Brugia malayi larval opioid receptor 0.0033 0.0328 0.0324
Brugia malayi nuclear receptor RXR 0.0148 0.2606 0.2603
Echinococcus multilocularis bloom syndrome protein 0.0021 0.0088 0.0096
Loa Loa (eye worm) hypothetical protein 0.0033 0.0328 0.0325
Echinococcus multilocularis 7TM GPCR, rhodopsin 0.0033 0.0328 0.0394
Loa Loa (eye worm) hypothetical protein 0.0033 0.0328 0.0325
Schistosoma mansoni amine GPCR 0.0033 0.0328 0.0407
Onchocerca volvulus 0.0047 0.0614 0.065
Echinococcus multilocularis GA binding protein alpha chain 0.0077 0.1203 0.1481
Echinococcus granulosus GA binding protein alpha chain 0.0077 0.1203 0.1481
Loa Loa (eye worm) TAR-binding protein 0.0067 0.1011 0.1008
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0033 0.0328 0.0407
Loa Loa (eye worm) nuclear Hormone Receptor family member 0.0313 0.5894 0.5892
Echinococcus granulosus thioredoxin glutathione reductase 0.0046 0.0595 0.0726
Leishmania major trypanothione reductase 0.0046 0.0595 0.4429
Brugia malayi GTP-binding regulatory protein Gs alpha-S chain, putative 0.0051 0.068 0.0676
Brugia malayi conserved hypotetical protein 0.0148 0.2606 0.2603
Schistosoma mansoni histone-lysine n-methyltransferase setb1 0.0062 0.0895 0.111
Schistosoma mansoni hypothetical protein 0.0175 0.3146 0.3903
Brugia malayi Nuclear hormone receptor family member nhr-41 0.0313 0.5894 0.5892
Loa Loa (eye worm) hypothetical protein 0.0232 0.4295 0.4293
Echinococcus granulosus nuclear receptor subfamily 4 group A 0.0148 0.2606 0.3224
Mycobacterium ulcerans cytochrome P450 185A4 Cyp185A4 0.0053 0.0717 0.1413
Echinococcus multilocularis Nuclear hormone receptor HR96 0.0148 0.2606 0.3224
Mycobacterium tuberculosis Probable cytochrome P450 141 Cyp141 0.0034 0.0345 0.0378
Echinococcus multilocularis rhodopsin orphan GPCR 0.0033 0.0328 0.0394
Echinococcus granulosus sodium and chloride dependent glycine 0.0044 0.0552 0.0672
Echinococcus granulosus orexin receptor type 2 0.0033 0.0328 0.0394
Loa Loa (eye worm) hypothetical protein 0.0148 0.2606 0.2604
Brugia malayi mbt repeat family protein 0.0048 0.0626 0.0622
Brugia malayi Cytochrome P450 family protein 0.0053 0.0717 0.0713
Echinococcus granulosus Basic leucine zipper bZIP transcription factor 0.0091 0.1474 0.1818
Echinococcus multilocularis FTZ F1 nuclear receptor protein 0.0313 0.5894 0.7309
Onchocerca volvulus 0.0033 0.0328 0.0343
Brugia malayi Ets-domain containing protein 0.0077 0.1203 0.1199
Schistosoma mansoni amine GPCR 0.0033 0.0328 0.0407
Mycobacterium ulcerans short-chain type dehydrogenase/reductase 0.0061 0.0877 0.1731
Echinococcus multilocularis tar DNA binding protein 0.0067 0.1011 0.1242
Loa Loa (eye worm) hypothetical protein 0.0073 0.1113 0.111
Echinococcus multilocularis pyruvate kinase 0.0036 0.039 0.0472
Onchocerca volvulus 0.0033 0.0328 0.0343
Echinococcus multilocularis serotonin transporter 0.0261 0.4864 0.6029
Brugia malayi Dopamine receptor protein 2 0.0033 0.0328 0.0324
Onchocerca volvulus 0.0033 0.0328 0.0343
Mycobacterium ulcerans cytochrome P450 123A3 Cyp123A3 0.0034 0.0345 0.0669
Echinococcus multilocularis rhodopsin orphan GPCR 0.0033 0.0328 0.0394
Schistosoma mansoni hypothetical protein 0.0034 0.0345 0.0428
Brugia malayi Melatonin receptor type 1A 0.0033 0.0328 0.0324
Schistosoma mansoni sodium-dependent amino acid transporter 0.0044 0.0552 0.0685
Schistosoma mansoni hypothetical protein 0.0033 0.0328 0.0407
Echinococcus granulosus COUP TF:Svp nuclear hormone receptor 0.0313 0.5894 0.7309
Echinococcus granulosus 3 hydroxyacyl coenzyme A dehydrogenase type 2 0.0061 0.0877 0.1076
Schistosoma mansoni Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) 0.0051 0.068 0.0843
Schistosoma mansoni nuclear receptor 0.0148 0.2606 0.3233
Brugia malayi PAS domain containing protein 0.0099 0.1645 0.1641
Echinococcus granulosus uncharacterized sodium dependent transporter 0.0044 0.0552 0.0672
Echinococcus multilocularis rhodopsin orphan GPCR 0.0033 0.0328 0.0394
Brugia malayi sulfakinin receptor protein 0.0033 0.0328 0.0324
Mycobacterium leprae conserved hypothetical protein 0.0073 0.1113 0.5075
Mycobacterium tuberculosis Conserved protein 0.0073 0.1113 0.1243
Echinococcus multilocularis lipoxygenase domain containing protein 0.0084 0.1338 0.1648
Echinococcus multilocularis lipoxygenase domain containing protein 0.0084 0.1338 0.1648
Loa Loa (eye worm) hypothetical protein 0.0033 0.0328 0.0325
Echinococcus multilocularis nuclear receptor subfamily 4 group A 0.0148 0.2606 0.3224
Schistosoma mansoni rab6-interacting 0.0084 0.1338 0.1659
Echinococcus multilocularis growth hormone secretagogue receptor type 1 0.0033 0.0328 0.0394
Echinococcus granulosus rhodopsin orphan GPCR 0.0033 0.0328 0.0394
Loa Loa (eye worm) hypothetical protein 0.0261 0.4864 0.4862
Echinococcus multilocularis rhodopsin orphan GPCR 0.0033 0.0328 0.0394
Echinococcus multilocularis COUP TF:Svp nuclear hormone receptor 0.0313 0.5894 0.7309
Echinococcus multilocularis pyruvate kinase 0.0036 0.039 0.0472
Mycobacterium tuberculosis Probable carbon monoxyde dehydrogenase (small chain) 0.0036 0.0381 0.0418
Brugia malayi latrophilin 2 splice variant baaae 0.0069 0.1036 0.1032
Mycobacterium ulcerans hypothetical protein 0.003 0.0275 0.0531
Trypanosoma cruzi Lanosterol 14-alpha demethylase 0.0034 0.0345 0.1736
Loa Loa (eye worm) pyruvate kinase 0.007 0.1073 0.107
Loa Loa (eye worm) beta-LACTamase domain containing family member 0.0073 0.1113 0.111
Schistosoma mansoni muscarinic acetylcholine (GAR) receptor 0.0033 0.0328 0.0407
Schistosoma mansoni lipoxygenase 0.015 0.2656 0.3296
Mycobacterium tuberculosis Probable cytochrome P450 143 Cyp143 0.0034 0.0345 0.0378
Echinococcus multilocularis uncharacterized sodium dependent transporter 0.0044 0.0552 0.0672
Mycobacterium ulcerans cytochrome P450 191A3 Cyp191A3 0.0034 0.0345 0.0669
Echinococcus multilocularis neuropeptide receptor 0.0033 0.0328 0.0394
Trichomonas vaginalis soluble guanylate cyclase gcy, putative 0.0026 0.0184 0.0187
Entamoeba histolytica tyrosyl-DNA phosphodiesterase, putative 0.0065 0.0961 1
Schistosoma mansoni sex comb on midleg homolog 0.0048 0.0626 0.0776
Loa Loa (eye worm) hypothetical protein 0.0148 0.2606 0.2604
Schistosoma mansoni biogenic amine receptor 0.0033 0.0328 0.0407
Echinococcus granulosus g protein linked acetylcholine receptor gar 2a 0.0033 0.0328 0.0394
Brugia malayi hypothetical protein 0.0071 0.1087 0.1083
Loa Loa (eye worm) hypothetical protein 0.0313 0.5894 0.5892
Schistosoma mansoni peptide (allatostatin)-like receptor 0.0033 0.0328 0.0407
Schistosoma mansoni histone-lysine n-methyltransferase setb1 0.0062 0.0895 0.111
Trypanosoma cruzi cytochrome p450-like protein, putative 0.0034 0.0345 0.1736
Chlamydia trachomatis Ssodium-dependent amino acid transporter 0.0044 0.0552 0.4143
Echinococcus granulosus nuclear receptor subfamily 1 group D 0.0165 0.2958 0.3662
Brugia malayi Unidentified vitellogenin-linked transcript protein 6, putative 0.0033 0.0328 0.0324
Mycobacterium ulcerans cytochrome P450 136A2 Cyp136A2 0.0034 0.0345 0.0669
Loa Loa (eye worm) hypothetical protein 0.0033 0.0328 0.0325
Echinococcus multilocularis rhodopsin orphan GPCR 0.0033 0.0328 0.0394
Schistosoma mansoni neuropeptide F-like receptor 0.0033 0.0328 0.0407
Schistosoma mansoni Tr4/Tr2 (homologue) 0.0313 0.5894 0.7312
Brugia malayi glutathione reductase 0.0046 0.0595 0.0591
Trichomonas vaginalis penicillin-binding protein, putative 0.0073 0.1113 0.1188
Plasmodium vivax thioredoxin reductase, putative 0.0046 0.0595 0.3545
Echinococcus multilocularis neuropeptide receptor 0.0033 0.0328 0.0394
Brugia malayi hypothetical protein 0.0408 0.7794 0.7793
Schistosoma mansoni biogenic amine (5HT) receptor 0.0033 0.0328 0.0407
Onchocerca volvulus 0.003 0.026 0.0269
Loa Loa (eye worm) hypothetical protein 0.0033 0.0328 0.0325
Schistosoma mansoni opsin-like receptor 0.0033 0.0328 0.0407
Mycobacterium tuberculosis Probable cytochrome P450 137 Cyp137 0.0034 0.0345 0.0378
Loa Loa (eye worm) nuclear hormone receptor-like 1 0.0165 0.2958 0.2956
Schistosoma mansoni survival motor neuron protein 0.0047 0.0614 0.0761
Loa Loa (eye worm) doublecortin family protein 0.0084 0.1338 0.1335
Echinococcus multilocularis geminin 0.0175 0.3146 0.3895
Loa Loa (eye worm) hypothetical protein 0.0084 0.1338 0.1335
Loa Loa (eye worm) hypothetical protein 0.0033 0.0328 0.0325
Toxoplasma gondii pyruvate kinase PyKII 0.0036 0.039 0.1705
Onchocerca volvulus 0.0084 0.1338 0.143
Schistosoma mansoni histone-lysine n-methyltransferase setb1 0.0062 0.0895 0.111
Echinococcus granulosus rhodopsin orphan GPCR 0.0033 0.0328 0.0394
Brugia malayi Steroid receptor seven-up type 2 0.0313 0.5894 0.5892
Mycobacterium tuberculosis Conserved protein 0.0073 0.1113 0.1243
Echinococcus multilocularis dro:myosuppressin receptor 0.0033 0.0328 0.0394
Echinococcus multilocularis neurogenic locus notch protein 0.0026 0.0187 0.0219
Schistosoma mansoni sex comb on midleg homolog 0.0048 0.0626 0.0776
Mycobacterium tuberculosis Probable cytochrome P450 130 Cyp130 0.0034 0.0345 0.0378
Echinococcus granulosus SAM and MBT domain containing protein 0.0048 0.0626 0.0764
Schistosoma mansoni RAR-like nuclear receptor 0.0313 0.5894 0.7312
Brugia malayi Dopamine receptor protein 1 0.0033 0.0328 0.0324
Brugia malayi nuclear receptor NHR-88 0.0148 0.2606 0.2603
Loa Loa (eye worm) hypothetical protein 0.0165 0.2958 0.2956
Plasmodium vivax hypothetical protein, conserved 0.0073 0.1113 0.8049
Echinococcus granulosus hepatocyte nuclear factor 4 alpha 0.0313 0.5894 0.7309
Brugia malayi Nuclear hormone receptor family member nhr-3 0.0313 0.5894 0.5892
Schistosoma mansoni cpg binding protein 0.0031 0.0293 0.0364
Loa Loa (eye worm) hypothetical protein 0.0033 0.0328 0.0325
Loa Loa (eye worm) hypothetical protein 0.0044 0.0552 0.0549
Schistosoma mansoni opsin-like receptor 0.0033 0.0328 0.0407
Loa Loa (eye worm) hypothetical protein 0.0033 0.0328 0.0325
Loa Loa (eye worm) hypothetical protein 0.0033 0.0328 0.0325
Echinococcus granulosus 5'partial|histone lysine N methyltransferase SETDB2 0.0059 0.0837 0.1027
Schistosoma mansoni family S12 unassigned peptidase (S12 family) 0.0073 0.1113 0.1381
Loa Loa (eye worm) hypothetical protein 0.0073 0.1113 0.111
Mycobacterium ulcerans carbon monoxyde dehydrogenase small chain CoxS 0.0036 0.0381 0.0742
Schistosoma mansoni peptide (FMRFamide/neurokinin-3)-like receptor 0.0033 0.0328 0.0407
Brugia malayi hypothetical protein 0.0033 0.0328 0.0324
Mycobacterium ulcerans cytochrome P450 150A6 Cyp150A6 0.0034 0.0345 0.0669
Leishmania major hypothetical protein, conserved 0.0073 0.1113 1
Onchocerca volvulus 0.0044 0.0552 0.0584
Echinococcus granulosus g protein coupled receptor 0.0033 0.0328 0.0394
Echinococcus multilocularis transfer RNA-Lys 0.0073 0.1132 0.1392
Schistosoma mansoni biogenic amine (dopamine) receptor 0.0033 0.0328 0.0407
Echinococcus multilocularis g-protein coupled receptor 0.0033 0.0328 0.0394
Loa Loa (eye worm) hypothetical protein 0.0033 0.0328 0.0325
Brugia malayi G protein-coupled receptor 0.0033 0.0328 0.0324
Trypanosoma brucei pyruvate kinase 1, putative 0.007 0.1073 0.9568
Loa Loa (eye worm) hypothetical protein 0.0033 0.0328 0.0325
Brugia malayi hypothetical protein 0.0017 0.001 0.0006
Mycobacterium ulcerans cytochrome P450 108B4 Cyp108B4 0.0034 0.0345 0.0669
Schistosoma mansoni hypothetical protein 0.0033 0.0328 0.0407
Loa Loa (eye worm) hypothetical protein 0.0032 0.0302 0.0299
Brugia malayi neuropeptide F receptor 0.0033 0.0328 0.0324
Schistosoma mansoni rab6-interacting 0.0084 0.1338 0.1659
Echinococcus multilocularis 0.0034 0.0345 0.0415
Loa Loa (eye worm) hypothetical protein 0.0033 0.0328 0.0325
Echinococcus multilocularis slit 2 protein 0.0026 0.0187 0.0219
Echinococcus granulosus dro:myosuppressin receptor 0.0033 0.0328 0.0394
Brugia malayi Cytochrome P450 family protein 0.0034 0.0345 0.0341
Schistosoma mansoni thyroid hormone receptor 0.0313 0.5894 0.7312
Mycobacterium leprae Conserved hypothetical protein 0.0034 0.0345 0.0881
Schistosoma mansoni peptide (allatostatin/somatostatin)-like receptor 0.0033 0.0328 0.0407
Echinococcus granulosus g protein coupled receptor 0.0033 0.0328 0.0394
Echinococcus granulosus pyruvate kinase 0.0036 0.039 0.0472
Loa Loa (eye worm) hypothetical protein 0.0033 0.0328 0.0325
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0033 0.0328 0.0407
Brugia malayi glutaminase DH11.1 0.0269 0.5017 0.5014
Loa Loa (eye worm) G-protein coupled receptor 0.0033 0.0328 0.0325
Echinococcus granulosus GPCR family 2 0.0032 0.0302 0.0362
Trichomonas vaginalis D-aminoacylase, putative 0.0073 0.1113 0.1188
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0033 0.0328 0.0407
Schistosoma mansoni peptide (FMRFamide/somatostatin)-like receptor 0.0033 0.0328 0.0407
Mycobacterium ulcerans aerobic-type carbon monoxide dehydrogenase subunit CoxL_2 0.0088 0.1425 0.2827
Brugia malayi hypothetical protein 0.0026 0.0187 0.0183
Loa Loa (eye worm) pyruvate kinase-PB 0.0049 0.0649 0.0646
Echinococcus granulosus pyruvate kinase 0.0036 0.039 0.0472
Echinococcus multilocularis nuclear receptor 2DBD gamma 0.0148 0.2606 0.3224
Echinococcus granulosus pikachurin 0.0026 0.0187 0.0219
Loa Loa (eye worm) hypothetical protein 0.0026 0.0187 0.0184
Schistosoma mansoni pyruvate kinase 0.0036 0.039 0.0484
Echinococcus multilocularis thyroid hormone receptor alpha 0.0313 0.5894 0.7309
Schistosoma mansoni alpha-1 adrenergic receptor 0.0033 0.0328 0.0407
Echinococcus multilocularis retinoic acid receptor rxr beta a retinoic acid receptor rxr alpha a retinoic acid receptor rxr alpha 0.0148 0.2606 0.3224
Schistosoma mansoni cytochrome P450 0.0034 0.0345 0.0428
Brugia malayi ecdysteroid receptor 0.0313 0.5894 0.5892
Loa Loa (eye worm) D-ets-4 DNA binding domain-containing protein 0.0077 0.1203 0.12
Echinococcus granulosus neuropeptide receptor 0.0033 0.0328 0.0394
Schistosoma mansoni sodium/chloride dependent transporter 0.0044 0.0552 0.0685
Echinococcus multilocularis histone lysine methyltransferase setb histone lysine methyltransferase eggless 0.0062 0.0895 0.1098
Echinococcus granulosus Aryl hydrocarbon receptor nuclear 0.0026 0.0184 0.0215
Loa Loa (eye worm) hypothetical protein 0.0148 0.2606 0.2604
Mycobacterium tuberculosis Probable lipase LipE 0.0073 0.1113 0.1243
Loa Loa (eye worm) hypothetical protein 0.0313 0.5894 0.5892
Echinococcus granulosus alpha 1A adrenergic receptor 0.0033 0.0328 0.0394
Brugia malayi beta-lactamase 0.0073 0.1113 0.1109
Echinococcus granulosus aldehyde dehydrogenase mitochondrial 0.0064 0.0947 0.1163
Mycobacterium ulcerans aerobic-type carbon monoxide dehydrogenase subunit CoxM_2 0.0063 0.0927 0.1832
Schistosoma mansoni nuclear hormone receptor 0.0313 0.5894 0.7312
Echinococcus granulosus neuropeptide FF receptor 2 0.0033 0.0328 0.0394
Trypanosoma brucei hypothetical protein, conserved 0.0073 0.1113 1
Schistosoma mansoni tar DNA-binding protein 0.0067 0.1011 0.1254
Echinococcus granulosus nuclear receptor 2DBD gamma 0.0313 0.5894 0.7309
Loa Loa (eye worm) hypothetical protein 0.0165 0.2958 0.2956
Brugia malayi hypothetical protein 0.0033 0.0328 0.0324
Loa Loa (eye worm) hypothetical protein 0.0019 0.0043 0.004
Schistosoma mansoni myelin transcription factor 1 myt1 0.0055 0.0758 0.094
Echinococcus multilocularis RUN 0.0084 0.1338 0.1648
Onchocerca volvulus Steroid hormone receptor family member cnr14 homolog 0.0313 0.5894 0.6336
Schistosoma mansoni opsin-like receptor 0.0033 0.0328 0.0407
Brugia malayi steroid hormone receptor 0.0313 0.5894 0.5892
Trichomonas vaginalis aldehyde oxidase, putative 0.0187 0.3392 0.3643
Brugia malayi C2-HC type zinc finger protein C.e-MyT1 0.0055 0.0758 0.0754
Brugia malayi Dopamine receptor protein 1, putative (partial) 0.0033 0.0328 0.0324
Echinococcus granulosus beta LACTamase domain containing family member 0.0073 0.1113 0.1369
Schistosoma mansoni polycystin 1-related 0.0084 0.1338 0.1659
Echinococcus multilocularis neuropeptides capa receptor 0.0033 0.0328 0.0394
Schistosoma mansoni aldehyde dehydrogenase 0.0064 0.0947 0.1175
Schistosoma mansoni glutaminase 0.0269 0.5017 0.6224
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0033 0.0328 0.0407
Loa Loa (eye worm) hypothetical protein 0.0033 0.0328 0.0325
Loa Loa (eye worm) glutaminase 0.0269 0.5017 0.5015
Echinococcus multilocularis thioredoxin glutathione reductase 0.0046 0.0595 0.0726
Trichomonas vaginalis DNA helicase recq1, putative 0.0021 0.0088 0.0084
Brugia malayi tailless protein 0.0148 0.2606 0.2603
Schistosoma mansoni hypothetical protein 0.0032 0.0302 0.0375
Echinococcus multilocularis beta LACTamase domain containing family member 0.0073 0.1113 0.1369
Loa Loa (eye worm) hypothetical protein 0.0033 0.0328 0.0325
Trypanosoma brucei trypanothione reductase 0.0046 0.0595 0.4405
Brugia malayi Thrombospondin N-terminal -like domain containing protein 0.0026 0.0187 0.0183
Brugia malayi GnHR receptor homolog 0.0033 0.0328 0.0324
Brugia malayi CXXC zinc finger family protein 0.003 0.026 0.0255
Mycobacterium tuberculosis Probable hydrolase 0.0073 0.1113 0.1243
Echinococcus granulosus Basic leucine zipper bZIP transcription 0.0039 0.0443 0.0537
Loa Loa (eye worm) hypothetical protein 0.0033 0.0328 0.0325
Brugia malayi Bloom's syndrome protein homolog 0.0021 0.0088 0.0084
Echinococcus multilocularis ecdysone induced protein 78C 0.0313 0.5894 0.7309
Schistosoma mansoni biogenic amine receptor 0.0033 0.0328 0.0407
Loa Loa (eye worm) nuclear hormone receptor family member nhr-31 0.0313 0.5894 0.5892
Echinococcus granulosus biogenic amine 5HT receptor 0.0033 0.0328 0.0394
Loa Loa (eye worm) hypothetical protein 0.0026 0.0187 0.0184
Echinococcus multilocularis cpg binding protein 0.0031 0.0293 0.0351
Echinococcus granulosus suppression of tumorigenicity 18 protein 0.0055 0.0758 0.0928
Mycobacterium tuberculosis Cytochrome P450 121 Cyp121 0.0034 0.0345 0.0378
Schistosoma mansoni hypothetical protein 0.0039 0.0443 0.055
Echinococcus multilocularis amiloride sensitive amine oxidase 0.017 0.305 0.3775
Schistosoma mansoni copper/topaquinone oxidase 0.017 0.305 0.3784
Treponema pallidum sodium- and chloride- dependent transporter 0.0261 0.4864 1
Mycobacterium ulcerans cytochrome P450 51B1 Cyp51B1 0.0034 0.0345 0.0669
Echinococcus granulosus tyrosyl DNA phosphodiesterase 1 0.0065 0.0961 0.1181
Onchocerca volvulus 0.0062 0.0895 0.0953
Loa Loa (eye worm) jmjC domain-containing protein 0.0059 0.0854 0.0851
Mycobacterium ulcerans cytochrome p450 150 cyp150 0.0034 0.0345 0.0669
Echinococcus multilocularis peptide (allatostatin:somatostatin) 0.0033 0.0328 0.0394
Onchocerca volvulus 0.0484 0.9296 1
Schistosoma mansoni biogenic amine (dopamine) receptor 0.0033 0.0328 0.0407
Trichomonas vaginalis adenylate and guanylate cyclases, putative 0.0026 0.0184 0.0187
Schistosoma mansoni zinc finger protein 0.0148 0.2606 0.3233
Echinococcus multilocularis sodium and chloride dependent glycine 0.0044 0.0552 0.0672
Loa Loa (eye worm) cytochrome P450 family protein 0.0053 0.0717 0.0714
Mycobacterium ulcerans short-chain type dehydrogenase/reductase 0.0061 0.0877 0.1731
Echinococcus granulosus lipoxygenase domain containing protein 0.0084 0.1338 0.1648
Echinococcus multilocularis G protein coupled 5 hydroxytryptamine receptor 0.0033 0.0328 0.0394
Echinococcus multilocularis pyroglutamylated rfamide peptide receptor 0.0033 0.0328 0.0394
Loa Loa (eye worm) Sodium:neurotransmitter symporter family protein 0.0044 0.0552 0.0549
Schistosoma mansoni histamine-responsive GPCR (AAF21638) 0.0033 0.0328 0.0407
Loa Loa (eye worm) hypothetical protein 0.0165 0.2958 0.2956
Plasmodium vivax hypothetical protein, conserved 0.0044 0.0552 0.317
Loa Loa (eye worm) MH2 domain-containing protein 0.0123 0.2119 0.2117
Schistosoma mansoni jun-related protein 0.0074 0.1136 0.141
Trichomonas vaginalis adenylate cyclase, type VII, putative 0.0026 0.0184 0.0187
Schistosoma mansoni nuclear receptor nhr-48 0.0148 0.2606 0.3233
Mycobacterium ulcerans cytochrome P450 105Q4 Cyp105Q4 0.0034 0.0345 0.0669
Brugia malayi putative neuropeptide receptor 0.0033 0.0328 0.0324
Brugia malayi hypothetical protein 0.0033 0.0328 0.0324
Echinococcus granulosus rhodopsin orphan GPCR 0.0033 0.0328 0.0394
Mycobacterium tuberculosis Probable carbon monoxyde dehydrogenase (medium chain) 0.0063 0.0927 0.1033
Schistosoma mansoni steroid hormone receptor ad4bp 0.0313 0.5894 0.7312
Echinococcus granulosus tachykinin peptides receptor 99D 0.0033 0.0328 0.0394
Mycobacterium tuberculosis Putative ferredoxin reductase 0.0106 0.178 0.1994
Onchocerca volvulus 0.0033 0.0328 0.0343
Brugia malayi G-protein-linked acetylcholine receptor protein 2, putative 0.0033 0.0328 0.0324
Loa Loa (eye worm) steroid hormone receptor 0.0313 0.5894 0.5892
Loa Loa (eye worm) fli-1 protein 0.0234 0.4322 0.432
Loa Loa (eye worm) hypothetical protein 0.0261 0.4864 0.4862
Brugia malayi 3-hydroxyacyl-CoA dehydrogenase type II 0.0061 0.0877 0.0873
Trypanosoma cruzi pyruvate kinase 2, putative 0.007 0.1073 0.957
Mycobacterium ulcerans cytochrome P450 144A4 Cyp144A4 0.0034 0.0345 0.0669
Trypanosoma cruzi pyruvate kinase 2, putative 0.007 0.1073 0.957
Loa Loa (eye worm) hypothetical protein 0.0084 0.1338 0.1335
Onchocerca volvulus 0.0033 0.0328 0.0343
Trypanosoma cruzi cytochrome P450, putative 0.0053 0.0717 0.5742
Mycobacterium ulcerans carbon monoxyde dehydrogenase large chain CoxL 0.0088 0.1425 0.2827
Plasmodium falciparum thioredoxin reductase 0.0046 0.0595 0.4292
Schistosoma mansoni pyruvate kinase 0.007 0.1073 0.1331
Schistosoma mansoni hypothetical protein 0.0032 0.0302 0.0375
Loa Loa (eye worm) hypothetical protein 0.0313 0.5894 0.5892
Schistosoma mansoni cell polarity protein 0.0026 0.0187 0.0232
Echinococcus multilocularis neuropeptides capa receptor 0.0236 0.4359 0.5402
Mycobacterium tuberculosis Possible cytochrome P450 126 Cyp126 0.0034 0.0345 0.0378
Trichomonas vaginalis D-aminoacylase, putative 0.0073 0.1113 0.1188
Echinococcus multilocularis Basic leucine zipper (bZIP) transcription factor 0.0091 0.1474 0.1818
Loa Loa (eye worm) hypoxia-induced factor 1 0.0307 0.578 0.5779
Mycobacterium tuberculosis Probable cytochrome P450 125 Cyp125 0.0034 0.0345 0.0378
Echinococcus multilocularis tyrosyl DNA phosphodiesterase 1 0.0065 0.0961 0.1181
Schistosoma mansoni thyrotropin-releasing hormone receptor 0.0033 0.0328 0.0407
Schistosoma mansoni neuropeptide receptor 0.0033 0.0328 0.0407
Trypanosoma cruzi tyrosyl-DNA Phosphodiesterase (Tdp1), putative 0.0065 0.0961 0.8369
Schistosoma mansoni FTZ-F1 nuclear receptor-like protein 0.0313 0.5894 0.7312
Echinococcus multilocularis biogenic amine (5HT) receptor 0.0033 0.0328 0.0394
Schistosoma mansoni 3-hydroxyacyl-CoA dehydrogenase 0.0061 0.0877 0.1088
Mycobacterium ulcerans cytochrome P450 140A5 Cyp140A5 0.0034 0.0345 0.0669
Leishmania major 3-oxoacyl-(acyl-carrier protein) reductase, putative 0.0061 0.0877 0.7455
Leishmania major pyruvate kinase 0.007 0.1073 0.957
Schistosoma mansoni sodium/chloride dependent transporter 0.0261 0.4864 0.6035
Trichomonas vaginalis adenylate and guanylate cyclases, putative 0.0026 0.0184 0.0187
Loa Loa (eye worm) hypothetical protein 0.0044 0.0552 0.0549
Brugia malayi Nuclear hormone receptor family member nhr-40 0.0313 0.5894 0.5892
Echinococcus granulosus dnaJ subfamily B 0.0422 0.806 1
Echinococcus granulosus hypothetical protein 0.0033 0.0328 0.0394
Mycobacterium tuberculosis Probable cytochrome P450 monooxygenase 142 Cyp142 0.0034 0.0345 0.0378
Leishmania major hypothetical protein, conserved 0.0026 0.0187 0.0043
Loa Loa (eye worm) norepinephrine transporter 0.0261 0.4864 0.4862
Brugia malayi beta-lactamase family protein 0.0073 0.1113 0.1109
Loa Loa (eye worm) tyrosyl-DNA phosphodiesterase 0.0065 0.0961 0.0958
Brugia malayi Cytochrome P450 family protein 0.0115 0.1967 0.1963
Echinococcus granulosus sodium:chloride dependent neurotransmitter 0.0044 0.0552 0.0672
Echinococcus granulosus single minded 2 0.0073 0.1132 0.1392
Echinococcus granulosus Nuclear hormone receptor HR96 0.0148 0.2606 0.3224
Brugia malayi hypothetical protein 0.0333 0.6293 0.6292
Schistosoma mansoni loxhd1 0.0084 0.1338 0.1659
Onchocerca volvulus 0.0261 0.4864 0.5227
Plasmodium falciparum amino acid transporter, putative 0.0044 0.0552 0.396
Chlamydia trachomatis pyruvate kinase 0.007 0.1073 1
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0033 0.0328 0.0407
Onchocerca volvulus Polycomb protein Sfmbt homolog 0.0048 0.0626 0.0663
Brugia malayi Nuclear hormone receptor E75 0.0148 0.2606 0.2603
Schistosoma mansoni peptide (FMRFamide/somatostatin)-like receptor 0.0033 0.0328 0.0407
Echinococcus multilocularis histone lysine N methyltransferase SETMAR 0.0062 0.0895 0.1098
Echinococcus multilocularis thyrotropin releasing hormone receptor 0.0033 0.0328 0.0394
Echinococcus multilocularis sex peptide receptor 0.0033 0.0328 0.0394
Loa Loa (eye worm) hypothetical protein 0.0033 0.0328 0.0325
Brugia malayi Dopamine receptor 0.0033 0.0328 0.0324
Trypanosoma brucei pyruvate kinase 1 0.007 0.1073 0.9568
Echinococcus granulosus Transcription factor JmjC domain containing protein 0.0058 0.0821 0.1006
Schistosoma mansoni sodium-dependent neurotransmitter transporter 0.0044 0.0552 0.0685
Brugia malayi Pyruvate kinase, muscle isozyme 0.007 0.1073 0.1069
Loa Loa (eye worm) hypothetical protein 0.0033 0.0328 0.0325
Brugia malayi Tachykinin-like peptides receptor 99D 0.0033 0.0328 0.0324
Trypanosoma cruzi PAB1-binding protein , putative 0.0026 0.0187 0.0043
Schistosoma mansoni transcription factor LCR-F1 0.0039 0.0443 0.055
Brugia malayi RNA binding protein 0.0067 0.1011 0.1007
Loa Loa (eye worm) hypothetical protein 0.0033 0.0328 0.0325
Schistosoma mansoni biogenic amine (dopamine) receptor 0.0033 0.0328 0.0407
Mycobacterium tuberculosis Possible cytochrome P450 135B1 Cyp135B1 0.0034 0.0345 0.0378
Schistosoma mansoni sodium-dependent neurotransmitter transporter 0.0044 0.0552 0.0685
Schistosoma mansoni neuropeptide receptor 0.0033 0.0328 0.0407
Mycobacterium ulcerans lipase LipD 0.0073 0.1113 0.2204
Leishmania major aldehyde dehydrogenase, mitochondrial precursor 0.0064 0.0947 0.8214
Onchocerca volvulus Dopamine\/Ecdysteroid receptor homolog 0.0033 0.0328 0.0343
Brugia malayi hypothetical protein 0.0033 0.0328 0.0324
Loa Loa (eye worm) hypothetical protein 0.0165 0.2958 0.2956
Loa Loa (eye worm) glutaminase 2 0.0269 0.5017 0.5015
Trichomonas vaginalis guanylate cyclase, putative 0.0026 0.0184 0.0187
Brugia malayi neuropeptide F receptor 0.0033 0.0328 0.0324
Loa Loa (eye worm) hypothetical protein 0.0313 0.5894 0.5892
Echinococcus multilocularis histone acetyltransferase MYST2 0.0055 0.0758 0.0928
Brugia malayi hypothetical protein 0.0148 0.2606 0.2603
Loa Loa (eye worm) follicle stimulating hormone receptor 0.0519 1 1
Trichomonas vaginalis pyruvate kinase, putative 0.007 0.1073 0.1145
Loa Loa (eye worm) hypothetical protein 0.0434 0.8306 0.8305
Brugia malayi hypothetical protein 0.0033 0.0328 0.0324
Loa Loa (eye worm) pyruvate kinase 0.007 0.1073 0.107
Loa Loa (eye worm) hypothetical protein 0.0033 0.0328 0.0325
Trypanosoma cruzi trypanothione reductase, putative 0.0046 0.0595 0.4429
Echinococcus granulosus nuclear receptor nhr 48 0.0148 0.2606 0.3224
Toxoplasma gondii histone lysine methyltransferase SET1 0.0058 0.0831 0.5408
Mycobacterium tuberculosis Possible conserved lipoprotein LpqK 0.0073 0.1113 0.1243
Echinococcus granulosus lysine specific demethylase 5A 0.0059 0.0854 0.1048
Echinococcus multilocularis orexin receptor type 2 0.0033 0.0328 0.0394
Echinococcus multilocularis aryl hydrocarbon receptor 0.0026 0.0184 0.0215
Onchocerca volvulus Protein ultraspiracle homolog 0.0313 0.5894 0.6336
Loa Loa (eye worm) hypothetical protein 0.0033 0.0328 0.0325
Mycobacterium tuberculosis NAD(P)H quinone reductase LpdA 0.0118 0.2015 0.2259
Toxoplasma gondii histone lysine methyltransferase SET/SUV39 0.0062 0.0895 0.5943
Brugia malayi Pre-SET motif family protein 0.0062 0.0895 0.0891
Brugia malayi nuclear receptor NHR-67 0.0148 0.2606 0.2603
Echinococcus granulosus tm gpcr rhodopsin 0.0033 0.0328 0.0394
Brugia malayi Pre-SET motif family protein 0.0425 0.8129 0.8128
Mycobacterium ulcerans cytochrome P450 187A4 Cyp187A4 0.0034 0.0345 0.0669
Echinococcus granulosus aryl hydrocarbon receptor 0.0026 0.0184 0.0215
Brugia malayi Sodium:neurotransmitter symporter family protein 0.0044 0.0552 0.0548
Echinococcus multilocularis neuropeptide receptor A26 0.0033 0.0328 0.0394
Plasmodium vivax glutathione reductase, putative 0.0046 0.0595 0.3545
Schistosoma mansoni hypothetical protein 0.0422 0.806 1
Echinococcus granulosus FTZ F1 nuclear receptor protein 0.0313 0.5894 0.7309
Schistosoma mansoni hypothetical protein 0.0033 0.0328 0.0407
Loa Loa (eye worm) hypothetical protein 0.0033 0.0328 0.0325
Brugia malayi hypothetical protein 0.0033 0.0328 0.0324
Brugia malayi Nuclear hormone receptor family member nhr-1 0.0313 0.5894 0.5892
Trypanosoma cruzi cytochrome P450, putative 0.0053 0.0717 0.5742
Brugia malayi hypothetical protein 0.0232 0.4295 0.4293
Echinococcus granulosus histone lysine methyltransferase setb 0.0062 0.0895 0.1098
Echinococcus multilocularis g protein coupled receptor 0.0033 0.0328 0.0394
Loa Loa (eye worm) hypothetical protein 0.0017 0.001 0.0006
Mycobacterium tuberculosis Probable esterase LipL 0.0073 0.1113 0.1243
Mycobacterium leprae Probable pyruvate kinase PykA 0.007 0.1073 0.4856
Schistosoma mansoni nuclear hormone receptor 0.0148 0.2606 0.3233
Schistosoma mansoni neuropeptide f receptor 76f 0.0033 0.0328 0.0407
Brugia malayi G protein-coupled receptor F59B2.13 0.0033 0.0328 0.0324
Echinococcus granulosus sodium dependent neurotransmitter transporter 0.0044 0.0552 0.0672
Brugia malayi Ligand-binding domain of nuclear hormone receptor family protein 0.0313 0.5894 0.5892
Mycobacterium tuberculosis Probable nitrite reductase [NAD(P)H] large subunit [FAD flavoprotein] NirB 0.0106 0.178 0.1994
Brugia malayi Hypothetical 52.5 kDa protein ZK945.1 in chromosome II, putative 0.0073 0.1113 0.1109
Loa Loa (eye worm) hypothetical protein 0.0033 0.0328 0.0325
Loa Loa (eye worm) hypothetical protein 0.0033 0.0328 0.0325
Mycobacterium ulcerans esterase/lipase LipP 0.0073 0.1113 0.2204
Schistosoma mansoni adenoreceptor 0.0033 0.0328 0.0407
Echinococcus multilocularis arachidonate 5 lipoxygenase 0.0301 0.5657 0.7015
Schistosoma mansoni jumonji domain containing protein 0.0058 0.0821 0.1018
Loa Loa (eye worm) hypothetical protein 0.0033 0.0328 0.0325
Mycobacterium ulcerans aldehyde dehydrogenase 0.0064 0.0947 0.1872
Echinococcus multilocularis somatostatin receptor 0.0033 0.0328 0.0394
Loa Loa (eye worm) mbt repeat family protein 0.0048 0.0626 0.0622
Brugia malayi hypothetical protein 0.0044 0.0552 0.0548
Loa Loa (eye worm) hypothetical protein 0.0044 0.0552 0.0549
Echinococcus multilocularis SAM and MBT domain containing protein 0.0048 0.0626 0.0764
Mycobacterium ulcerans hypothetical protein 0.0073 0.1113 0.2204
Loa Loa (eye worm) MBCTL1 0.0055 0.0758 0.0755
Toxoplasma gondii hypothetical protein 0.0044 0.0552 0.3064
Toxoplasma gondii hypothetical protein 0.0086 0.1378 1
Leishmania major lanosterol 14-alpha-demethylase, putative 0.0034 0.0345 0.1736
Schistosoma mansoni pyruvate kinase 0.007 0.1073 0.1331
Loa Loa (eye worm) nuclear receptor nhr-7B 0.0148 0.2606 0.2604
Loa Loa (eye worm) CYP4Cod1 0.0053 0.0717 0.0714
Loa Loa (eye worm) melatonin receptor type 1A 0.0033 0.0328 0.0325
Echinococcus multilocularis g protein linked acetylcholine receptor gar 2a 0.0033 0.0328 0.0394
Loa Loa (eye worm) hypothetical protein 0.0033 0.0328 0.0325
Onchocerca volvulus 0.0044 0.0552 0.0584
Mycobacterium tuberculosis Cytochrome P450 51 Cyp51 (CYPL1) (P450-L1A1) (sterol 14-alpha demethylase) (lanosterol 14-alpha demethylase) (P450-14DM) 0.0034 0.0345 0.0378
Echinococcus granulosus RUN 0.0084 0.1338 0.1648
Trypanosoma brucei cytochrome P450, putative 0.0053 0.0717 0.5724
Echinococcus granulosus neurogenic locus notch protein 0.0026 0.0187 0.0219
Echinococcus granulosus jun protein 0.0091 0.1474 0.1818
Mycobacterium ulcerans carbon monoxyde dehydrogenase large chain CoxL 0.0055 0.0774 0.1526
Schistosoma mansoni nuclear hormone receptor 0.0148 0.2606 0.3233
Trypanosoma brucei Lanosterol 14-alpha demethylase 0.0034 0.0345 0.1701
Loa Loa (eye worm) hypothetical protein 0.0066 0.098 0.0977
Brugia malayi Nuclear hormone receptor-like 1 0.0313 0.5894 0.5892
Loa Loa (eye worm) TYRA-2 protein 0.0033 0.0328 0.0325
Trichomonas vaginalis DNA helicase recq, putative 0.0021 0.0088 0.0084
Schistosoma mansoni hypothetical protein 0.0033 0.0328 0.0407
Brugia malayi Thioredoxin reductase 0.0046 0.0595 0.0591
Brugia malayi hypothetical protein 0.0033 0.0328 0.0324
Loa Loa (eye worm) hypothetical protein 0.0073 0.1113 0.111
Echinococcus multilocularis cadherin EGF LAG seven pass G type receptor 0.0032 0.0302 0.0362
Loa Loa (eye worm) hypothetical protein 0.0033 0.0328 0.0325
Echinococcus granulosus lipoxygenase domain containing protein 0.0084 0.1338 0.1648
Echinococcus multilocularis rhodopsin orphan GPCR 0.0033 0.0328 0.0394
Echinococcus granulosus uncharacterized sodium dependent transporter 0.0044 0.0552 0.0672
Loa Loa (eye worm) hypothetical protein 0.0049 0.0649 0.0646
Mycobacterium tuberculosis Probable cytochrome P450 128 Cyp128 0.0034 0.0345 0.0378
Toxoplasma gondii Sodium:neurotransmitter symporter family protein 0.0044 0.0552 0.3064
Loa Loa (eye worm) hypothetical protein 0.0033 0.0328 0.0325
Echinococcus granulosus Nuclear hormone receptor family member nhr 41 0.0313 0.5894 0.7309
Brugia malayi AKH receptor 0.0033 0.0328 0.0324
Schistosoma mansoni hypothetical protein 0.0047 0.0614 0.0761
Brugia malayi Serotonin/octopamine receptor family protein 7 0.0033 0.0328 0.0324
Loa Loa (eye worm) hypothetical protein 0.0055 0.0758 0.0755
Onchocerca volvulus 0.0033 0.0328 0.0343
Loa Loa (eye worm) hypothetical protein 0.0033 0.0328 0.0325
Loa Loa (eye worm) G-protein coupled receptor 0.0033 0.0328 0.0325
Brugia malayi G-protein coupled receptor 0.0033 0.0328 0.0324
Brugia malayi jmjC domain containing protein 0.0058 0.0821 0.0817
Echinococcus multilocularis transcription factor Dp 1 0.0038 0.0418 0.0506
Echinococcus granulosus histone acetyltransferase MYST2 0.0055 0.0758 0.0928
Brugia malayi RNA recognition motif domain containing protein 0.0067 0.1011 0.1007
Schistosoma mansoni retinoic acid receptor RXR 0.0313 0.5894 0.7312
Schistosoma mansoni growth hormone secretagogue receptor 0.0033 0.0328 0.0407
Brugia malayi Cytochrome P450 family protein 0.0053 0.0717 0.0713
Brugia malayi hypothetical protein 0.0084 0.1338 0.1334
Brugia malayi putative neuropeptide receptor NPR1 0.0033 0.0328 0.0324
Echinococcus multilocularis guanine nucleotide binding protein G(s) subunit 0.0051 0.068 0.0831
Brugia malayi Nuclear hormone receptor family member nhr-19 0.0313 0.5894 0.5892
Loa Loa (eye worm) hypothetical protein 0.0148 0.2606 0.2604
Schistosoma mansoni mixed-lineage leukemia protein mll 0.0065 0.0965 0.1197
Echinococcus multilocularis GPCR, family 2 0.0032 0.0302 0.0362
Echinococcus granulosus cpg binding protein 0.0031 0.0293 0.0351
Schistosoma mansoni sodium-dependent neurotransmitter transporter 0.0044 0.0552 0.0685
Trichomonas vaginalis xanthine dehydrogenase, putative 0.0187 0.3392 0.3643
Loa Loa (eye worm) neuropeptide F receptor 0.0033 0.0328 0.0325
Echinococcus granulosus cadherin EGF LAG seven pass G type receptor 0.0032 0.0302 0.0362
Brugia malayi Fli-1 protein 0.0234 0.4322 0.432
Onchocerca volvulus Nuclear receptor subfamily 6 group A member 1 homolog 0.0148 0.2606 0.2796
Mycobacterium tuberculosis Probable cytochrome P450 136 Cyp136 0.0034 0.0345 0.0378
Plasmodium falciparum pyruvate kinase 2 0.0036 0.039 0.2717
Loa Loa (eye worm) hypothetical protein 0.0333 0.6293 0.6292
Echinococcus multilocularis sodium dependent neurotransmitter transporter 0.0044 0.0552 0.0672
Echinococcus granulosus thyrotropin releasing hormone receptor 0.0033 0.0328 0.0394
Loa Loa (eye worm) hypothetical protein 0.0073 0.1113 0.111
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0033 0.0328 0.0407
Echinococcus multilocularis tm gpcr rhodopsin gpcr rhodopsin superfamily 0.0033 0.0328 0.0394
Echinococcus granulosus neuropeptides capa receptor 0.0236 0.4359 0.5402
Loa Loa (eye worm) hypothetical protein 0.01 0.1668 0.1665
Mycobacterium tuberculosis Probable conserved lipoprotein 0.0073 0.1113 0.1243
Echinococcus granulosus 7TM GPCR rhodopsin 0.0033 0.0328 0.0394
Echinococcus granulosus amiloride sensitive amine oxidase 0.017 0.305 0.3775
Schistosoma mansoni biogenic amine (octopamine/dopamine) receptor 0.0033 0.0328 0.0407
Brugia malayi nuclear hormone receptor family member odr-7 0.0148 0.2606 0.2603
Plasmodium vivax pyruvate kinase, putative 0.007 0.1073 0.7701
Echinococcus multilocularis rhodopsin orphan GPCR 0.0033 0.0328 0.0394
Schistosoma mansoni slit 0.0026 0.0187 0.0232
Trichomonas vaginalis penicillin-binding protein, putative 0.0073 0.1113 0.1188
Schistosoma mansoni nuclear hormone receptor nor-1/nor-2 0.0313 0.5894 0.7312
Loa Loa (eye worm) DR-78 0.0148 0.2606 0.2604
Mycobacterium leprae PROBABLE NADH DEHYDROGENASE NDH 0.0106 0.178 0.8715
Onchocerca volvulus 0.0084 0.1338 0.143
Echinococcus granulosus growth hormone secretagogue receptor type 1 0.0033 0.0328 0.0394
Loa Loa (eye worm) hypothetical protein 0.0033 0.0328 0.0325
Plasmodium vivax SET domain protein, putative 0.0062 0.0895 0.615
Trichomonas vaginalis adenylate and guanylate cyclases, putative 0.0026 0.0184 0.0187
Plasmodium falciparum glutathione reductase 0.0046 0.0595 0.4292
Echinococcus granulosus pyruvate kinase 0.007 0.1073 0.132
Echinococcus granulosus ecdysone induced protein 78C 0.0313 0.5894 0.7309
Brugia malayi nuclear receptor RXR 0.0165 0.2958 0.2955
Plasmodium falciparum transporter, putative 0.0044 0.0552 0.396
Echinococcus multilocularis polycomb protein SCMH1 0.0048 0.0626 0.0764
Brugia malayi Sulfatase family protein 0.0017 0.001 0.0006
Brugia malayi hypothetical protein 0.0033 0.0328 0.0324
Brugia malayi TAR-binding protein 0.0067 0.1011 0.1007
Brugia malayi Nuclear hormone receptor family member nhr-25 0.0313 0.5894 0.5892
Leishmania major cytochrome p450-like protein 0.0034 0.0345 0.1736
Loa Loa (eye worm) hypothetical protein 0.0148 0.2606 0.2604
Echinococcus granulosus endonuclease exonuclease phosphatase 0.0189 0.3434 0.4253
Brugia malayi hypothetical protein 0.0039 0.0443 0.0439
Leishmania major cytochrome p450-like protein 0.0053 0.0717 0.5742
Loa Loa (eye worm) neuropeptide F receptor 0.0033 0.0328 0.0325
Loa Loa (eye worm) RNA binding protein 0.0067 0.1011 0.1008
Echinococcus granulosus nuclear receptor 2DBD gamma 0.0313 0.5894 0.7309
Echinococcus multilocularis Nuclear hormone receptor family member nhr 41 0.0313 0.5894 0.7309
Echinococcus multilocularis g protein coupled receptor 0.0033 0.0328 0.0394
Trichomonas vaginalis conserved hypothetical protein 0.0026 0.0184 0.0187
Loa Loa (eye worm) hypothetical protein 0.0261 0.4864 0.4862
Schistosoma mansoni Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) 0.0051 0.068 0.0843
Trypanosoma brucei tyrosyl-DNA Phosphodiesterase (Tdp1), putative 0.0065 0.0961 0.8362
Onchocerca volvulus 0.0033 0.0328 0.0343
Echinococcus granulosus rhodopsin orphan GPCR 0.0033 0.0328 0.0394
Brugia malayi gonadotropin-releasing hormone receptor 2 0.0033 0.0328 0.0324
Schistosoma mansoni biogenic amine receptor 0.0033 0.0328 0.0407
Loa Loa (eye worm) hypothetical protein 0.0033 0.0328 0.0325
Loa Loa (eye worm) hypothetical protein 0.0148 0.2606 0.2604
Brugia malayi calcium-independent alpha-latrotoxin receptor 2, putative 0.0032 0.0302 0.0298
Brugia malayi Sodium:neurotransmitter symporter family protein 1, putative 0.0044 0.0552 0.0548
Plasmodium falciparum pyruvate kinase 0.007 0.1073 0.7967
Trypanosoma cruzi PAB1-binding protein , putative 0.0026 0.0187 0.0043
Schistosoma mansoni sodium/chloride dependent transporter 0.0044 0.0552 0.0685
Echinococcus granulosus pyroglutamylated rfamide peptide receptor 0.0033 0.0328 0.0394
Onchocerca volvulus 0.0033 0.0328 0.0343
Echinococcus granulosus FTZ F1 alpha 0.0313 0.5894 0.7309
Echinococcus granulosus G protein coupled receptor 139 0.0033 0.0328 0.0394
Echinococcus multilocularis pyruvate kinase 0.0056 0.0778 0.0953
Mycobacterium ulcerans glutaminase 0.0269 0.5017 1
Schistosoma mansoni hepatocyte nuclear factor 4-alpha (hnf-4-alpha) 0.0148 0.2606 0.3233
Schistosoma mansoni nuclear hormone receptor superfamily protein-related 0.0148 0.2606 0.3233
Brugia malayi Serotonin receptor 0.0033 0.0328 0.0324
Echinococcus multilocularis rhodopsin orphan GPCR 0.0033 0.0328 0.0394
Mycobacterium ulcerans beta-lactamase 0.0073 0.1113 0.2204
Loa Loa (eye worm) hypothetical protein 0.0033 0.0328 0.0325
Echinococcus granulosus transcription factor Dp 1 0.0038 0.0418 0.0506
Echinococcus granulosus neuropeptides capa receptor 0.0033 0.0328 0.0394
Schistosoma mansoni hypothetical protein 0.0084 0.1338 0.1659
Mycobacterium tuberculosis Probable membrane NADH dehydrogenase NdhA 0.0106 0.178 0.1994
Mycobacterium tuberculosis Probable cytochrome P450 124 Cyp124 0.0034 0.0345 0.0378
Echinococcus multilocularis pyruvate kinase 0.007 0.1073 0.132
Echinococcus multilocularis sodium and chloride dependent glycine 0.0044 0.0552 0.0672
Schistosoma mansoni hypothetical protein 0.0032 0.0302 0.0375
Echinococcus multilocularis Basic leucine zipper (bZIP) transcription 0.0039 0.0443 0.0537
Onchocerca volvulus Pyruvate kinase homolog 0.007 0.1073 0.1145
Schistosoma mansoni ets-related 0.0234 0.4322 0.5363
Mycobacterium tuberculosis Probable cytochrome P450 132 Cyp132 0.0034 0.0345 0.0378
Echinococcus multilocularis Transcription factor, JmjC domain containing protein 0.0058 0.0821 0.1006
Schistosoma mansoni photoreceptor-specific nuclear receptor related 0.0313 0.5894 0.7312
Echinococcus granulosus thyroid hormone receptor alpha 0.0148 0.2606 0.3224
Onchocerca volvulus 0.0073 0.1113 0.1188
Schistosoma mansoni jumonji/arid domain-containing protein 0.0059 0.0854 0.106
Echinococcus granulosus guanine nucleotide binding protein Gs subunit 0.0051 0.068 0.0831
Echinococcus granulosus G protein coupled 5 hydroxytryptamine receptor 0.0033 0.0328 0.0394
Plasmodium falciparum LCCL domain-containing protein 0.0084 0.1338 1
Loa Loa (eye worm) hypothetical protein 0.0044 0.0552 0.0549
Echinococcus multilocularis nuclear receptor 2DBD gamma 0.0313 0.5894 0.7309
Echinococcus granulosus Nuclear hormone receptor HR96 0.0148 0.2606 0.3224
Echinococcus granulosus sodium and chloride dependent glycine 0.0044 0.0552 0.0672
Schistosoma mansoni nuclear receptor 2DBD-gamma 0.0313 0.5894 0.7312
Schistosoma mansoni biogenic amine (5HT) receptor 0.0033 0.0328 0.0407
Loa Loa (eye worm) hypothetical protein 0.0026 0.0184 0.018
Loa Loa (eye worm) hypothetical protein 0.0033 0.0328 0.0325
Schistosoma mansoni lipoxygenase 0.0301 0.5657 0.7019
Loa Loa (eye worm) hypothetical protein 0.0165 0.2958 0.2956
Mycobacterium tuberculosis Probable short-chain type dehydrogenase/reductase 0.0061 0.0877 0.0976
Brugia malayi Calcitonin receptor-like protein seb-1 0.01 0.1668 0.1664
Echinococcus granulosus peptide allatostatin:somatostatin 0.0033 0.0328 0.0394
Onchocerca volvulus Pyruvate kinase homolog 0.007 0.1073 0.1145
Echinococcus granulosus arachidonate 5 lipoxygenase 0.0301 0.5657 0.7015
Schistosoma mansoni nuclear receptor 0.0148 0.2606 0.3233
Onchocerca volvulus 0.0073 0.1132 0.1208
Echinococcus multilocularis serotonin receptor 0.0033 0.0328 0.0394
Echinococcus multilocularis diuretic hormone 44 receptor GPRdih2 0.0032 0.0302 0.0362
Loa Loa (eye worm) solute carrier family 6 member 4 0.0261 0.4864 0.4862
Loa Loa (eye worm) nuclear hormone receptor family member nhr-14 0.0313 0.5894 0.5892
Mycobacterium ulcerans carbon monoxyde dehydrogenase medium chain CoxM 0.0063 0.0927 0.1832
Toxoplasma gondii aldehyde dehydrogenase 0.0064 0.0947 0.6383
Schistosoma mansoni tar DNA-binding protein 0.0067 0.1011 0.1254
Echinococcus granulosus survival motor neuron protein 1 0.0232 0.4295 0.5323
Mycobacterium ulcerans aldehyde dehydrogenase 0.0064 0.0947 0.1872
Brugia malayi Tyrosyl-DNA phosphodiesterase family protein 0.0065 0.0961 0.0958
Mycobacterium tuberculosis Probable cytochrome P450 140 Cyp140 0.0034 0.0345 0.0378
Mycobacterium tuberculosis Possible cytochrome P450 135A1 Cyp135A1 0.0034 0.0345 0.0378
Onchocerca volvulus 0.0033 0.0328 0.0343
Schistosoma mansoni norepinephrine/norepinephrine transporter 0.0044 0.0552 0.0685
Schistosoma mansoni neuropeptide receptor 0.0033 0.0328 0.0407
Echinococcus multilocularis sodium:chloride dependent neurotransmitter 0.0044 0.0552 0.0672
Schistosoma mansoni tar DNA-binding protein 0.0067 0.1011 0.1254
Brugia malayi nuclear receptor subfamily 1, group D, member 1, putative 0.0148 0.2606 0.2603
Giardia lamblia Pyruvate kinase 0.007 0.1073 1
Loa Loa (eye worm) Sodium:neurotransmitter symporter family protein 0.0044 0.0552 0.0549
Schistosoma mansoni aldehyde dehydrogenase 0.0064 0.0947 0.1175
Schistosoma mansoni chondroitin sulfate proteoglycan-related 0.0026 0.0187 0.0232
Schistosoma mansoni norepinephrine/norepinephrine transporter 0.0044 0.0552 0.0685
Loa Loa (eye worm) hypothetical protein 0.0048 0.0626 0.0622
Schistosoma mansoni family S12 unassigned peptidase (S12 family) 0.0073 0.1113 0.1381
Echinococcus multilocularis survival motor neuron protein 1 0.0232 0.4295 0.5323
Schistosoma mansoni ecdysone-induced protein 78c (dr-78) 0.0165 0.2958 0.367
Echinococcus multilocularis G-protein coupled receptor, putative 0.0033 0.0328 0.0394
Loa Loa (eye worm) RNA recognition domain-containing protein domain-containing protein 0.0067 0.1011 0.1008
Onchocerca volvulus 0.0026 0.0184 0.0187
Brugia malayi Nuclear hormone receptor-like 1 0.0165 0.2958 0.2955
Leishmania major cytochrome p450-like protein 0.0034 0.0345 0.1736
Mycobacterium ulcerans cytochrome P450 124A1, Cyp124A1 0.0034 0.0345 0.0669
Echinococcus multilocularis allatostatin A receptor 0.0033 0.0328 0.0394
Echinococcus multilocularis serotonin receptor 0.0033 0.0328 0.0394
Mycobacterium tuberculosis Possible penicillin-binding protein 0.0463 0.8887 1
Schistosoma mansoni jumonji/arid domain-containing protein 0.0059 0.0854 0.106
Loa Loa (eye worm) pyruvate kinase 0.007 0.1073 0.107
Echinococcus multilocularis guanine nucleotide binding protein G(s) subunit 0.0051 0.068 0.0831
Loa Loa (eye worm) GTP-binding regulatory protein Gs alpha-S chain 0.0051 0.068 0.0677
Mycobacterium tuberculosis Probable dehydrogenase 0.0106 0.178 0.1994
Loa Loa (eye worm) hypothetical protein 0.0033 0.0328 0.0325
Mycobacterium ulcerans cytochrome P450 189A7 Cyp189A7 0.0034 0.0345 0.0669
Loa Loa (eye worm) nuclear hormone receptor 0.0148 0.2606 0.2604
Echinococcus multilocularis G protein coupled receptor 139 0.0033 0.0328 0.0394
Mycobacterium ulcerans putative regulatory protein 0.0073 0.1132 0.2241
Brugia malayi jmjC domain containing protein 0.0059 0.0854 0.085
Echinococcus granulosus tm gpcr rhodopsin 0.0033 0.0328 0.0394
Brugia malayi Serotonin receptor 0.0033 0.0328 0.0324
Trichomonas vaginalis xanthine dehydrogenase, putative 0.0187 0.3392 0.3643
Loa Loa (eye worm) G-protein-linked acetylcholine receptor protein 2 0.0033 0.0328 0.0325
Echinococcus granulosus retinoic acid receptor rxr beta a 0.0313 0.5894 0.7309
Mycobacterium leprae putative cytochrome p450 0.0034 0.0345 0.0881
Schistosoma mansoni tyrosyl-DNA phosphodiesterase 0.0065 0.0961 0.1193
Echinococcus granulosus slit 2 protein 0.0026 0.0187 0.0219
Echinococcus multilocularis tm gpcr rhodopsin gpcr rhodopsin superfamily 0.0033 0.0328 0.0394
Echinococcus multilocularis dnaJ subfamily B 0.0422 0.806 1
Loa Loa (eye worm) hypothetical protein 0.0148 0.2606 0.2604
Schistosoma mansoni histamine h1 receptor 0.0033 0.0328 0.0407
Schistosoma mansoni tar DNA-binding protein 0.0067 0.1011 0.1254
Onchocerca volvulus Pyruvate kinase homolog 0.007 0.1073 0.1145
Echinococcus multilocularis g protein linked acetylcholine receptor gar 2a 0.0033 0.0328 0.0394
Loa Loa (eye worm) hypothetical protein 0.0313 0.5894 0.5892
Onchocerca volvulus 0.0033 0.0328 0.0343
Loa Loa (eye worm) hypothetical protein 0.0026 0.0187 0.0184
Schistosoma mansoni thyroid hormone receptor 0.0313 0.5894 0.7312
Loa Loa (eye worm) RecQ helicase 0.0021 0.0088 0.0084
Echinococcus multilocularis hepatocyte nuclear factor 4 alpha 0.0313 0.5894 0.7309
Echinococcus multilocularis pyruvate kinase 0.007 0.1073 0.132
Schistosoma mansoni hypothetical protein 0.0292 0.5476 0.6795
Loa Loa (eye worm) glutathione reductase 0.0046 0.0595 0.0592
Loa Loa (eye worm) hypothetical protein 0.0148 0.2606 0.2604
Schistosoma mansoni cpg binding protein 0.0031 0.0293 0.0364
Loa Loa (eye worm) cytochrome P450 family protein 0.0053 0.0717 0.0714
Echinococcus granulosus diuretic hormone 44 receptor GPRdih2 0.0032 0.0302 0.0362
Onchocerca volvulus 0.0033 0.0328 0.0343
Brugia malayi Nuclear hormone receptor-like 1 0.0165 0.2958 0.2955
Loa Loa (eye worm) hypothetical protein 0.0148 0.2606 0.2604
Brugia malayi Latrophilin receptor protein 2 0.0032 0.0302 0.0298
Echinococcus granulosus serotonin transporter 0.0261 0.4864 0.6029
Onchocerca volvulus 0.0071 0.1087 0.116
Echinococcus granulosus tm gpcr rhodopsin 0.0033 0.0328 0.0394
Echinococcus granulosus cytochrome P450 2K1 0.0034 0.0345 0.0415
Onchocerca volvulus 0.0033 0.0328 0.0343
Mycobacterium ulcerans cytochrome P450 126A3 Cyp126A3 0.0034 0.0345 0.0669
Schistosoma mansoni hypothetical protein 0.017 0.305 0.3784
Echinococcus granulosus fmrfamide receptor 0.0033 0.0328 0.0394
Brugia malayi hypothetical protein 0.0033 0.0328 0.0324
Loa Loa (eye worm) hypothetical protein 0.0044 0.0552 0.0549
Brugia malayi Nuclear hormone receptor family member nhr-49 0.0313 0.5894 0.5892
Echinococcus granulosus rhodopsin orphan GPCR 0.0033 0.0328 0.0394
Trichomonas vaginalis conserved hypothetical protein 0.0026 0.0184 0.0187
Loa Loa (eye worm) abnormal epIthelia family member 0.0026 0.0187 0.0184
Loa Loa (eye worm) hypothetical protein 0.0088 0.1425 0.1422
Loa Loa (eye worm) hypothetical protein 0.0148 0.2606 0.2604
Plasmodium vivax pyruvate kinase 2, putative 0.0036 0.039 0.1765
Brugia malayi laminin alpha chain 0.0026 0.0187 0.0183
Echinococcus multilocularis tachykinin peptides receptor 99D 0.0033 0.0328 0.0394
Loa Loa (eye worm) hypothetical protein 0.0073 0.1113 0.111
Echinococcus granulosus 7tm_1 domain containing protein 0.0033 0.0328 0.0394
Echinococcus granulosus g protein linked acetylcholine receptor gar 2a 0.0033 0.0328 0.0394
Loa Loa (eye worm) nuclear hormone receptor family member nhr-1 0.0313 0.5894 0.5892
Brugia malayi hypothetical protein 0.0084 0.1338 0.1334
Brugia malayi photoreceptor-specific nuclear receptor 0.0313 0.5894 0.5892
Onchocerca volvulus 0.0033 0.0328 0.0343
Schistosoma mansoni single-minded 0.0099 0.1645 0.204
Toxoplasma gondii Sodium:neurotransmitter symporter family protein 0.0044 0.0552 0.3064
Loa Loa (eye worm) hypothetical protein 0.0033 0.0328 0.0325
Brugia malayi cytochrome P450 0.0034 0.0345 0.0341
Mycobacterium tuberculosis Probable cytochrome P450 138 Cyp138 0.0034 0.0345 0.0378
Leishmania major pyruvate kinase 0.007 0.1073 0.957
Loa Loa (eye worm) 5-hydroxytryptamine 2C receptor 0.0033 0.0328 0.0325
Brugia malayi Iron-sulfur cluster assembly accessory protein 0.0047 0.0614 0.061
Echinococcus granulosus sex peptide receptor 0.0033 0.0328 0.0394
Brugia malayi ORL1-like opioid receptor 0.0033 0.0328 0.0324
Loa Loa (eye worm) cytochrome P450 family protein 0.0115 0.1967 0.1964
Trichomonas vaginalis esterase, putative 0.0073 0.1113 0.1188
Plasmodium falciparum ataxin-2 like protein, putative 0.0026 0.0187 0.1156
Echinococcus granulosus rhodopsin orphan GPCR 0.0033 0.0328 0.0394
Loa Loa (eye worm) hypothetical protein 0.0033 0.0328 0.0325
Brugia malayi Ets-domain containing protein 0.0077 0.1203 0.1199
Loa Loa (eye worm) hypothetical protein 0.0062 0.0895 0.0892
Schistosoma mansoni tar DNA-binding protein 0.0067 0.1011 0.1254
Echinococcus granulosus geminin 0.0175 0.3146 0.3895
Brugia malayi nuclear hormone receptor 0.0313 0.5894 0.5892
Schistosoma mansoni sodium/chloride dependent neurotransmitter transporter 0.0044 0.0552 0.0685
Echinococcus granulosus biogenic amine 5HT receptor 0.0033 0.0328 0.0394
Schistosoma mansoni myosin xvIII 0.0033 0.0328 0.0407
Mycobacterium ulcerans cytochrome P450 143A4 Cyp143A4 0.0034 0.0345 0.0669
Trichomonas vaginalis guanylate cyclase, putative 0.0026 0.0184 0.0187
Schistosoma mansoni coup transcription factor 0.0313 0.5894 0.7312
Trypanosoma cruzi hypothetical protein, conserved 0.0073 0.1113 1
Trichomonas vaginalis glutaminase, putative 0.0269 0.5017 0.5392
Echinococcus granulosus guanine nucleotide binding protein Gs subunit 0.0051 0.068 0.0831
Echinococcus multilocularis neuropeptide s receptor 0.0033 0.0328 0.0394
Brugia malayi bZIP transcription factor family protein 0.0091 0.1474 0.1471
Schistosoma mansoni aryl hydrocarbon receptor 0.0099 0.1645 0.204
Echinococcus granulosus neuropeptide Y receptor 0.0033 0.0328 0.0394
Loa Loa (eye worm) serotonin transporter b 0.0261 0.4864 0.4862
Mycobacterium leprae DIHYDROLIPOAMIDE DEHYDROGENASE LPD (LIPOAMIDE REDUCTASE (NADH)) (LIPOYL DEHYDROGENASE) (DIHYDROLIPOYL DEHYDROGENASE) (DIAPHORASE 0.0118 0.2015 1
Echinococcus granulosus neuropeptide receptor A26 0.0033 0.0328 0.0394
Echinococcus granulosus somatostatin receptor 0.0033 0.0328 0.0394
Echinococcus multilocularis neuropeptide FF receptor 2 0.0033 0.0328 0.0394
Loa Loa (eye worm) hypothetical protein 0.0033 0.0328 0.0325
Mycobacterium tuberculosis Probable NADH dehydrogenase Ndh 0.0106 0.178 0.1994
Onchocerca volvulus 0.0073 0.1113 0.1188
Echinococcus multilocularis 3 hydroxyacyl coenzyme A dehydrogenase type 2 0.0061 0.0877 0.1076
Brugia malayi RE15519p 0.0033 0.0328 0.0324
Echinococcus granulosus g protein coupled receptor 0.0033 0.0328 0.0394
Plasmodium vivax amine transporter, putative 0.0044 0.0552 0.317
Plasmodium falciparum ataxin-2 like protein, putative 0.0026 0.0187 0.1156
Loa Loa (eye worm) hypothetical protein 0.0313 0.5894 0.5892
Loa Loa (eye worm) hypothetical protein 0.0044 0.0552 0.0549
Echinococcus multilocularis Aryl hydrocarbon receptor nuclear 0.0026 0.0184 0.0215
Onchocerca volvulus Neuropeptide F receptor homolog 0.0033 0.0328 0.0343
Mycobacterium tuberculosis Probable cytochrome P450 123 Cyp123 0.0034 0.0345 0.0378
Loa Loa (eye worm) 3-hydroxyacyl-CoA dehydrogenase type II 0.0057 0.0795 0.0792
Treponema pallidum hypothetical protein 0.003 0.0275 0.0227
Loa Loa (eye worm) hypothetical protein 0.007 0.1073 0.107
Trypanosoma cruzi Lanosterol 14-alpha demethylase 0.0034 0.0345 0.1736
Toxoplasma gondii ABC1 family protein 0.0073 0.1113 0.7778
Brugia malayi Corticotropin releasing factor receptor 2 precursor, putative 0.01 0.1668 0.1664
Loa Loa (eye worm) hypothetical protein 0.0026 0.0187 0.0184
Echinococcus granulosus nuclear receptor 2DBD gamma 0.0148 0.2606 0.3224
Onchocerca volvulus 0.0148 0.2606 0.2796
Onchocerca volvulus 0.0033 0.0328 0.0343
Echinococcus granulosus neuropeptide Y receptor 0.0033 0.0328 0.0394
Mycobacterium ulcerans carbon monoxyde dehydrogenase small chain CoxS 0.0036 0.0381 0.0742
Schistosoma mansoni amine GPCR 0.0033 0.0328 0.0407
Treponema pallidum quinoline 2-oxidoreductase 0.003 0.0261 0.0197
Echinococcus multilocularis jun protein 0.0091 0.1474 0.1818
Loa Loa (eye worm) hypothetical protein 0.0313 0.5894 0.5892
Mycobacterium ulcerans cytochrome P450 125A7 Cyp125A7 0.0034 0.0345 0.0669
Onchocerca volvulus 0.0048 0.0626 0.0663
Trypanosoma cruzi tyrosyl-DNA Phosphodiesterase (Tdp1), putative 0.0065 0.0961 0.8369
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0033 0.0328 0.0407

Activities

Activity type Activity value Assay description Source Reference
1/krel (functional) = 1.17 Solvolytic stability was measured relative to p-hydroxyphenethyl bromide ChEMBL. 6292424
Injected (functional) = 0.39 % compound injected per gram uterus at 6 hr ChEMBL. 6292424
Injected dose (functional) = 0.18 % Percent injected dose per gram thyroid at 6 hr ChEMBL. 6292424
Injected dose (functional) = 0.25 % Percent injected dose per gram thyroid at 1 hr with unlabeled estradiol ChEMBL. 6292424
Injected dose (functional) = 0.26 % Percent injected dose per gram thyroid at 1 hr ChEMBL. 6292424
Injected dose (functional) = 0.29 % Percent injected dose per gram Muscle at 1 hr ChEMBL. 6292424
Injected dose (functional) = 0.3 % Percent injected dose per gram Muscle at 1 hr with unlabeled estradiol ChEMBL. 6292424
Injected dose (functional) = 0.34 % Percent injected dose per gram spleen at 1 hr with unlabeled estradiol ChEMBL. 6292424
Injected dose (functional) = 0.35 % Percent injected dose per gram Muscle at 6 hr ChEMBL. 6292424
Injected dose (functional) = 0.37 % Percent injected dose per gram Muscle at 3h ChEMBL. 6292424
Injected dose (functional) = 0.38 % Percent injected dose per gram spleen at 1 hr ChEMBL. 6292424
Injected dose (functional) = 0.38 % Percent injected dose per gram esophagus at 1 hr ChEMBL. 6292424
Injected dose (functional) = 0.42 % Percent injected dose per gram lung at 1 hr ChEMBL. 6292424
Injected dose (functional) = 0.56 % Percent injected dose per gram esophagus at 1 hr with unlabeled estradiol ChEMBL. 6292424
Injected dose (functional) = 0.6 % Percent injected dose per gram spleen at 3h ChEMBL. 6292424
Injected dose (functional) = 0.61 % Percent injected dose per gram esophagus at 3h ChEMBL. 6292424
Injected dose (functional) = 0.68 % Percent injected dose per gram esophagus at 6 hr ChEMBL. 6292424
Injected dose (functional) = 0.69 % Percent injected dose per gram spleen at 6 hr ChEMBL. 6292424
Injected dose (functional) = 0.7 % Percent injected dose per gram kidney at 1 hr with unlabeled estradiol ChEMBL. 6292424
Injected dose (functional) = 0.72 % Percent injected dose per gram Ovaries at 1 hr with unlabeled estradiol ChEMBL. 6292424
Injected dose (functional) = 0.75 % Percent injected dose per gram blood at 1 hr ChEMBL. 6292424
Injected dose (functional) = 0.8 % Percent injected dose per gram lung at 1 hr with unlabeled estradiol ChEMBL. 6292424
Injected dose (functional) = 0.84 % Percent injected dose per gram kidney at 3h ChEMBL. 6292424
Injected dose (functional) = 0.9 % Percent injected dose per gram kidney at 6 hr ChEMBL. 6292424
Injected dose (functional) = 0.93 % Percent injected dose per gram liver at 6 hr ChEMBL. 6292424
Injected dose (functional) = 0.94 % Percent injected dose per gram kidney at 1 hr ChEMBL. 6292424
Injected dose (functional) = 0.95 % Percent injected dose per gram Uterus at 1 hr with unlabeled estradiol. ChEMBL. 6292424
Injected dose (functional) = 0.95 % Percent injected dose per gram lung at 3h ChEMBL. 6292424
Injected dose (functional) = 0.98 % Percent injected dose per gram blood at 1 hr with unlabeled estradiol ChEMBL. 6292424
Injected dose (functional) = 1.02 % Percent injected dose per gram lung at 6 hr ChEMBL. 6292424
Injected dose (functional) = 1.05 % Percent injected dose per gram liver at 3h ChEMBL. 6292424
Injected dose (functional) = 1.24 % Percent injected dose per gram blood at 3h ChEMBL. 6292424
Injected dose (functional) = 1.28 % Percent injected dose per gram Ovaries at 3h ChEMBL. 6292424
Injected dose (functional) = 1.28 % Percent injected dose per gram liver at 1 hr ChEMBL. 6292424
Injected dose (functional) = 1.36 % Percent injected dose per gram blood at 6 hr ChEMBL. 6292424
Injected dose (functional) = 1.38 % Percent injected dose per gram Ovaries at 1 hr ChEMBL. 6292424
Injected dose (functional) = 1.46 % Percent injected dose per gram liver at 1 hr with unlabeled estradiol ChEMBL. 6292424
Injected dose (functional) = 1.93 % Percent injected dose per gram Ovaries at 6 hr ChEMBL. 6292424
Injected dose (functional) = 3.16 % Percent injected dose per gram Uterus at 1 hr ChEMBL. 6292424
Injected dose (functional) = 3.19 % Percent injected dose per gram Uterus at 6 hr ChEMBL. 6292424
Injected dose (functional) = 3.59 % Percent injected dose per gram Uterus at 3h ChEMBL. 6292424
Injected dose (g) (functional) = 0.09 % Percent injected dose per gram thyroid at 3h ChEMBL. 6292424
RAC (binding) = 150 The ratio of association constant for estrogen receptor using [3H]-estradiol as a tracer, relative to estradiol ChEMBL. 6292423
RAC (binding) = 150 The ratio of association constant for estrogen receptor using [3H]-estradiol as a tracer, relative to estradiol ChEMBL. 6292423
Ratio (functional) = 0.08 Thyroid/blood distribution ratio was determined in immature female rats at 3h ChEMBL. 6292424
Ratio (functional) = 0.13 Thyroid/blood distribution ratio was determined in immature female rats at 6 hr ChEMBL. 6292424
Ratio (functional) = 0.25 Thyroid/blood distribution ratio was determined in immature female rats at 1 hr with unlabeled estradiol ChEMBL. 6292424
Ratio (functional) = 0.26 Muscle/blood distribution ratio was determined in immature female rats at 6 hr ChEMBL. 6292424
Ratio (functional) = 0.29 Muscle/blood distribution ratio was determined in immature female rats at 3h ChEMBL. 6292424
Ratio (functional) = 0.31 Muscle/blood distribution ratio was determined immature female rats at 1 hr with unlabeled estradiol ChEMBL. 6292424
Ratio (functional) = 0.32 Thyroid/blood distribution ratio was determined in immature female rats at 1 hr ChEMBL. 6292424
Ratio (functional) = 0.47 Uptake ratio of compound was measured with 16-alpha-[125I]-iodo-17-beta-estradiol in immature rats at 3h ChEMBL. 6292424
Ratio (functional) = 0.48 Muscle/blood distribution ratio was determined in immature female rats at 1 hr ChEMBL. 6292424
Ratio (functional) = 0.48 Spleen/blood distribution ratio was determined immature female rats at 3h ChEMBL. 6292424
Ratio (functional) = 0.49 Esophagus/blood distribution ratio was determined in immature female rats at 3h ChEMBL. 6292424
Ratio (functional) = 0.5 Esophagus/blood distribution ratio was determined in immature female rats at 6 hr ChEMBL. 6292424
Ratio (functional) = 0.51 Spleen/blood distribution ratio was determined in immature female rats at 1 hr with unlabeled estradiol ChEMBL. 6292424
Ratio (functional) = 0.52 Spleen/blood distribution ratio was determined immature female rats at 1 hr ChEMBL. 6292424
Ratio (functional) = 0.54 Esophagus/blood distribution ratio was determined in immature female rats at 1 hr ChEMBL. 6292424
Ratio (functional) = 0.55 Spleen/blood distribution ratio was determined immature female rats at 6 hr ChEMBL. 6292424
Ratio (functional) = 0.58 Uptake ratio was measured with 16-alpha-[125I]-iodo-17-beta-estradiol in immature rats at 6 hr ChEMBL. 6292424
Ratio (functional) = 0.59 Esophagus/blood distribution ratio was determined in immature female rats at 1 hr with unlabeled estradiol ChEMBL. 6292424
Ratio (functional) = 0.6 Lung/blood distribution ratio was determined in immature female rats at 1 hr ChEMBL. 6292424
Ratio (functional) = 0.68 Lung/blood distribution ratio was determined in immature female rats at 3h ChEMBL. 6292424
Ratio (functional) = 0.69 Liver/blood distribution ratio was determined in immature female rats at 6 hr ChEMBL. 6292424
Ratio (functional) = 0.74 Ovary/blood distribution ratio was determined in immature female rats at 1 hr with unlabeled estradiol ChEMBL. 6292424
Ratio (functional) = 0.76 Kidney/blood distribution ratio was determined in immature female rats at 3h ChEMBL. 6292424
Ratio (functional) = 0.76 Lung/blood distribution ratio was determined in immature female rats at 6 hr ChEMBL. 6292424
Ratio (functional) = 0.82 Lung/blood distribution ratio was determined determined in immature female rats at 1 hr with unlabeled estradiol ChEMBL. 6292424
Ratio (functional) = 0.84 Liver/blood distribution ratio was determined in immature female rats at 3h ChEMBL. 6292424
Ratio (functional) = 0.84 Kidney/blood distribution ratio was determined in immature female rats at 1 hr with unlabeled estradiol ChEMBL. 6292424
Ratio (functional) = 0.89 Kidney/blood distribution ratio was determined in immature female rats at 6 hr ChEMBL. 6292424
Ratio (functional) = 0.98 Uterus/blood distribution of compound was measured in immature female rats at 1 hr with unlabeled estradiol ChEMBL. 6292424
Ratio (functional) = 1 Tissue/blood distribution ratio was measured in immature female rats at 1 hr ChEMBL. 6292424
Ratio (functional) = 1 Tissue/blood distribution ratio was measured in immature female rats at 1h, unlabled estradiol (18 microg) coinjected ChEMBL. 6292424
Ratio (functional) = 1 Tissue/blood distribution ratio was measured in immature female rats at 3h ChEMBL. 6292424
Ratio (functional) = 1 Tissue/blood distribution ratio was measured in immature female rats at 6 hr ChEMBL. 6292424
Ratio (functional) = 1.23 Ovary/blood distribution ratio was determined in immature female rats at 3h ChEMBL. 6292424
Ratio (functional) = 1.29 Kidney/blood distribution ratio was determined in immature female rats at 1 hr ChEMBL. 6292424
Ratio (functional) = 1.41 Ovary/blood distribution ratio was determined in immature female rats at 6 hr ChEMBL. 6292424
Ratio (functional) = 1.51 Liver/blood distribution ratio was determined in immature female rats at 1 hr with unlabeled estradiol ChEMBL. 6292424
Ratio (functional) = 1.69 Liver/blood distribution ratio was determined in immature female rats at 1 hr ChEMBL. 6292424
Ratio (functional) = 1.98 Ovary/blood distribution ratio was determined in immature female rats at 1 hr ChEMBL. 6292424
Ratio (functional) = 2.51 Uterus/blood distribution ratio was measured in immature female rats at 6 hr ChEMBL. 6292424
Ratio (functional) = 2.86 Uterus/blood distribution ratio was measured in immature female rats at 3h ChEMBL. 6292424
Ratio (functional) = 4.49 Uterus/blood distribution ratio was measured in immature female rats at 1 hr ChEMBL. 6292424
Ratio (functional) = 0.33 % Uptake ratio was measured with 16-alpha-[125I]-iodo-17-beta-estradiol in immature rats at 6 hr ChEMBL. 6292424

Phenotypes

Whole-cell/tissue/organism interactions

We have no records of whole-cell/tissue assays done with this compound What does this mean?

Many chemical entities in TDR Targets come from high-throughput screenings with whole cells or tissue samples, and not all assayed compounds have been tested against a single a single target protein, probably because they get ruled out during screening process. Even if these compounds may have not been of interest in the original screening, they may come as interesting leads for other screening assays. Furthermore, we may be able to propose drug-target associations using chemical similarities and network patterns.

Annotated phenotypes:

We have no manually annotated phenotypes for this drug. What does this mean? / Care to help?
In TDR Targets, information about phenotypes that are caused by drugs, or by genetic manipulation of cells (e.g. gene knockouts or knockdowns) is manually curated from the literature. These descriptions help to describe the potential of the target for drug development. If no information is available for this gene or if the information is incomplete, this may mean that i) the papers containing this information either appeared after the curation effort for this organism was carried out or they were inadvertently missed by curators; or that ii) the curation effort for this organism has not yet started.
 
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External resources for this compound

Bibliographic References

2 literature references were collected for this gene.

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