Detailed information for compound 328000

Basic information

Technical information
  • Name: Unnamed compound
  • MW: 453.451 | Formula: C21H23N7O5
  • H donors: 4 H acceptors: 7 LogP: 0.66 Rotable bonds: 6
    Rule of 5 violations (Lipinski): 1
  • SMILES: OC[C@@H]1OC([C@H]([C@@H]1O)O)n1cnc2c1nc(nc2NC)n1ncc(c1)c1ccc(cc1)OC
  • InChi: 1S/C21H23N7O5/c1-22-18-15-19(27(10-23-15)20-17(31)16(30)14(9-29)33-20)26-21(25-18)28-8-12(7-24-28)11-3-5-13(32-2)6-4-11/h3-8,10,14,16-17,20,29-31H,9H2,1-2H3,(H,22,25,26)/t14-,16-,17-,20?/m1/s1
  • InChiKey: PBPQOBBHDIVSFT-FIALEDGQSA-N  


Substructure search Similarity search

Network

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Synonyms

No synonyms found for this compound

Targets

Known targets for this compound

No curated genes were found associated with this compound

Predicted pathogen targets for this compound

By orthology
No druggable targets predicted by orthology data
By sequence similarity to non orthologous known druggable targets
No druggable targets predicted by sequence similarity
Obtained from network model

Ranking Plot

Putative Targets List

Species Potential target Raw Global Species
Schistosoma mansoni peptide (allatostatin/somatostatin)-like receptor 0.0135 0.0351 0.0545
Echinococcus granulosus Protein patched homolog 1 0.0085 0.0201 0.0311
Loa Loa (eye worm) pre-SET domain-containing protein family protein 0.0429 0.1247 0.1774
Echinococcus multilocularis sterol regulatory element binding protein 0.0085 0.0201 0.0197
Echinococcus multilocularis peroxisome assembly protein 26 0.1253 0.3759 0.3757
Loa Loa (eye worm) hypothetical protein 0.0135 0.0351 0.0497
Echinococcus granulosus tubulin delta chain 0.041 0.119 0.1873
Onchocerca volvulus 0.0025 0.0018 0.0101
Echinococcus multilocularis serotonin receptor 0.0135 0.0351 0.0348
Schistosoma mansoni tubulin subunit beta 0.1644 0.4949 0.7808
Echinococcus granulosus tachykinin peptides receptor 99D 0.0135 0.0351 0.0549
Trichomonas vaginalis conserved hypothetical protein 0.0025 0.0016 0.0032
Schistosoma mansoni regulator of G protein signaling 0.0025 0.0016 0.0015
Brugia malayi ecdysone receptor 0.0025 0.0018 0.003
Echinococcus granulosus neuropeptides capa receptor 0.0135 0.0351 0.0549
Trichomonas vaginalis chromodomain helicase DNA binding protein, putative 0.0019 0.000000000036275 0.000000000073297
Trichomonas vaginalis multidrug resistance protein 1, 2, putative 0.0022 0.0006 0.0013
Echinococcus granulosus rhodopsin orphan GPCR 0.0135 0.0351 0.0549
Loa Loa (eye worm) hypothetical protein 0.0029 0.0029 0.0037
Loa Loa (eye worm) cytochrome P450 family protein 0.0053 0.0103 0.0142
Schistosoma mansoni lipoxygenase 0.0412 0.1195 0.1877
Trichomonas vaginalis tubulin epsilon chain, putative 0.1253 0.3759 0.7595
Echinococcus multilocularis survival motor neuron protein 1 0.0238 0.0666 0.0662
Trichomonas vaginalis PIKK family atypical protein kinase 0.0069 0.015 0.0302
Loa Loa (eye worm) hypothetical protein 0.0034 0.0043 0.0058
Echinococcus multilocularis histone lysine N methyltransferase MLL3 0.0024 0.0013 0.0009
Brugia malayi nuclear receptor RXR 0.0034 0.0043 0.0082
Schistosoma mansoni lipoxygenase 0.023 0.0641 0.1002
Onchocerca volvulus 0.0086 0.0202 0.1359
Leishmania major beta tubulin 0.1644 0.4949 1
Loa Loa (eye worm) tubulin alpha-3 chain 0.0752 0.2233 0.3179
Echinococcus granulosus tubulin alpha 1C chain 0.1253 0.3759 0.5929
Loa Loa (eye worm) hypothetical protein 0.0059 0.012 0.0168
Brugia malayi tailless protein 0.0025 0.0018 0.003
Leishmania major beta tubulin 0.1644 0.4949 1
Schistosoma mansoni peptide (FMRFamide/somatostatin)-like receptor 0.0135 0.0351 0.0545
Schistosoma mansoni mixed-lineage leukemia protein mll 0.0024 0.0013 0.001
Brugia malayi Smad1 0.0041 0.0066 0.0127
Leishmania major alpha tubulin 0.1253 0.3759 0.7592
Brugia malayi beta-tubulin, identical 0.1644 0.4949 1
Schistosoma mansoni hypothetical protein 0.0082 0.0191 0.0292
Schistosoma mansoni histone-lysine n-methyltransferase setb1 0.0063 0.0133 0.02
Schistosoma mansoni ataxia telangiectasia mutated (atm)-related 0.0092 0.0222 0.034
Echinococcus multilocularis tubulin subunit beta 0.1644 0.4949 0.4947
Loa Loa (eye worm) hypothetical protein 0.0025 0.0018 0.0021
Trichomonas vaginalis phosphofructokinase, putative 0.003 0.0033 0.0066
Brugia malayi Intermediate filament tail domain containing protein 0.0082 0.0191 0.0381
Schistosoma mansoni opsin-like receptor 0.0135 0.0351 0.0545
Echinococcus granulosus nuclear factor of activated T cells 5 0.0074 0.0167 0.0257
Schistosoma mansoni 6-phosphofructokinase 0.0112 0.0282 0.0435
Schistosoma mansoni amine GPCR 0.0135 0.0351 0.0545
Trichomonas vaginalis lipid A export ATP-binding/permease protein msba, putative 0.0022 0.0006 0.0013
Onchocerca volvulus 0.0135 0.0351 0.2379
Trichomonas vaginalis multidrug resistance protein 1, 2, putative 0.0022 0.0006 0.0013
Loa Loa (eye worm) phosphatidylinositol 3 0.0092 0.0222 0.0312
Trichomonas vaginalis abcb9, putative 0.0022 0.0006 0.0013
Trichomonas vaginalis PIKK family atypical protein kinase 0.0073 0.0164 0.0332
Echinococcus granulosus 6 phosphofructokinase 0.0112 0.0282 0.0439
Entamoeba histolytica tubulin family protein 0.1644 0.4949 1
Entamoeba histolytica hypothetical protein 0.0023 0.001 0.0007
Onchocerca volvulus 0.0488 0.1427 0.9732
Loa Loa (eye worm) hypothetical protein 0.0025 0.0016 0.0018
Brugia malayi hypothetical protein 0.0134 0.035 0.0701
Echinococcus granulosus dro:myosuppressin receptor 0.0135 0.0351 0.0549
Echinococcus granulosus 7TM GPCR rhodopsin 0.0135 0.0351 0.0549
Plasmodium falciparum glutathione reductase 0.0033 0.0042 0.0073
Echinococcus granulosus ecdysone induced protein 78C 0.0059 0.012 0.0184
Toxoplasma gondii pyruvate dehydrogenase complex subunit PDH-E3II 0.0033 0.0042 0.0073
Leishmania major tyrosyl-DNA phosphodiesterase 1 0.0066 0.0143 0.0277
Loa Loa (eye worm) abnormal chemotaxis protein 14 0.0085 0.0201 0.0282
Echinococcus multilocularis tubulin alpha chain 0.1253 0.3759 0.3757
Echinococcus multilocularis ATP binding cassette subfamily B (MDR:TAP) 0.0022 0.0006 0.0003
Toxoplasma gondii ATP-dependent DNA helicase, RecQ family protein 0.0029 0.0029 0.0045
Schistosoma mansoni jumonji domain containing protein 0.0059 0.0121 0.0181
Trypanosoma cruzi target of rapamycin kinase 3 0.0073 0.0164 0.0263
Echinococcus multilocularis nuclear receptor 2DBD gamma 0.0059 0.012 0.0117
Mycobacterium ulcerans phosphopantetheinyl transferase, PptII 0.0023 0.001 0.0057
Trypanosoma cruzi PAS-domain containing phosphoglycerate kinase, putative 0.0051 0.0098 0.0127
Echinococcus granulosus g protein linked acetylcholine receptor gar 2a 0.0135 0.0351 0.0549
Trypanosoma cruzi trypanothione reductase, putative 0.0096 0.0234 0.0405
Leishmania major beta tubulin 0.1644 0.4949 1
Brugia malayi Nuclear hormone receptor family member nhr-1 0.0059 0.012 0.0238
Trichomonas vaginalis multidrug resistance protein 1, 2, putative 0.0022 0.0006 0.0013
Trypanosoma cruzi STE group serine/threonine-protein kinase, putative 0.0052 0.01 0.0133
Schistosoma mansoni nuclear receptor 0.0025 0.0018 0.0018
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0135 0.0351 0.0545
Echinococcus granulosus 5'partial|ATP binding cassette sub family B 0.0021 0.0006 0.0003
Brugia malayi Tubulin beta chain 0.0501 0.1467 0.2959
Loa Loa (eye worm) unidentified vitellogenin-linked transcript protein 6 0.0135 0.0351 0.0497
Echinococcus multilocularis regulator of G protein signaling 3 0.0025 0.0016 0.0012
Trichomonas vaginalis PIKK family atypical protein kinase 0.005 0.0092 0.0186
Toxoplasma gondii tubulin/FtsZ family, GTPase domain-containing protein 0.0911 0.2716 0.5481
Loa Loa (eye worm) histone methyltransferase 0.0029 0.0029 0.0036
Schistosoma mansoni coup transcription factor 0.0059 0.012 0.018
Echinococcus granulosus rhodopsin orphan GPCR 0.0135 0.0351 0.0549
Trichomonas vaginalis PIKK family atypical protein kinase 0.0073 0.0164 0.0332
Trichomonas vaginalis lipid A export ATP-binding/permease protein msba, putative 0.0022 0.0006 0.0013
Trypanosoma cruzi PAS-domain containing phosphoglycerate kinase, putative 0.0051 0.0098 0.0127
Schistosoma mansoni amine GPCR 0.0135 0.0351 0.0545
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0135 0.0351 0.0545
Echinococcus multilocularis beta tubulin 0.1644 0.4949 0.4947
Trypanosoma brucei beta tubulin 0.0911 0.2716 0.5478
Brugia malayi hypothetical protein 0.0135 0.0351 0.0704
Plasmodium vivax tubulin alpha chain, putative 0.1253 0.3759 0.7592
Mycobacterium tuberculosis Probable dehydrogenase 0.022 0.061 0.5113
Echinococcus granulosus tubulin beta 4A class IVa 0.1644 0.4949 0.7808
Trichomonas vaginalis tubulin beta chain, putative 0.1253 0.3759 0.7595
Loa Loa (eye worm) nuclear factor I 0.0023 0.001 0.001
Trichomonas vaginalis tubulin alpha chain, putative 0.0911 0.2716 0.5487
Loa Loa (eye worm) hypothetical protein 0.0135 0.0351 0.0497
Loa Loa (eye worm) hypothetical protein 0.0059 0.012 0.0168
Schistosoma mansoni aryl hydrocarbon receptor 0.0198 0.0544 0.085
Brugia malayi putative neuropeptide receptor NPR1 0.0135 0.0351 0.0704
Brugia malayi alpha-tubulin 0.1253 0.3759 0.7594
Toxoplasma gondii tubulin/FtsZ family, GTPase domain-containing protein 0.0437 0.1273 0.2562
Loa Loa (eye worm) hypothetical protein 0.0135 0.0351 0.0497
Loa Loa (eye worm) hypothetical protein 0.0059 0.012 0.0168
Schistosoma mansoni RAR-like nuclear receptor 0.0059 0.012 0.018
Schistosoma mansoni hypothetical protein 0.0082 0.0191 0.0292
Loa Loa (eye worm) DR-78 0.0025 0.0018 0.0021
Echinococcus multilocularis sex peptide receptor 0.0135 0.0351 0.0348
Brugia malayi G protein-coupled receptor F59B2.13 0.0135 0.0351 0.0704
Loa Loa (eye worm) thioredoxin reductase 0.0096 0.0234 0.0329
Toxoplasma gondii CMGC kinase, MAPK family (ERK) MAPK-1 0.0103 0.0256 0.0504
Trichomonas vaginalis glutathione reductase, putative 0.0033 0.0042 0.0086
Leishmania major ubiquitin hydrolase, putative,cysteine peptidase, Clan CA, family C19, putative 0.0037 0.0054 0.0097
Echinococcus multilocularis ATP dependent DNA helicase Q1 0.0029 0.0029 0.0025
Trypanosoma brucei alpha tubulin 0.1253 0.3759 0.7591
Entamoeba histolytica tyrosyl-DNA phosphodiesterase, putative 0.0066 0.0143 0.0277
Trichomonas vaginalis conserved hypothetical protein 0.0025 0.0016 0.0032
Entamoeba histolytica FKBP-rapamycin associated protein (FRAP), putative 0.0092 0.0222 0.0435
Loa Loa (eye worm) hypothetical protein 0.0135 0.0351 0.0497
Schistosoma mansoni growth hormone secretagogue receptor 0.0135 0.0351 0.0545
Schistosoma mansoni hypothetical protein 0.0826 0.2458 0.3873
Toxoplasma gondii protease inhibitor PI2 0.0059 0.0119 0.0228
Brugia malayi Serotonin receptor 0.0135 0.0351 0.0704
Brugia malayi G-protein coupled receptor 0.0135 0.0351 0.0704
Brugia malayi Thioredoxin reductase 0.0096 0.0234 0.0467
Brugia malayi hypothetical protein 0.0135 0.0351 0.0704
Trichomonas vaginalis fructose-bisphosphate aldolase, putative 0.0283 0.0804 0.1624
Brugia malayi Dopamine receptor 0.0135 0.0351 0.0704
Trichomonas vaginalis CMGC family protein kinase 0.0103 0.0256 0.0517
Echinococcus granulosus multidrug resistance protein 1 0.0022 0.0006 0.0004
Echinococcus multilocularis mothers against decapentaplegic 5 0.0041 0.0066 0.0062
Schistosoma mansoni tyrosyl-DNA phosphodiesterase 0.0066 0.0143 0.0216
Echinococcus multilocularis lysine specific demethylase 5A 0.0059 0.0121 0.0117
Loa Loa (eye worm) hypothetical protein 0.0021 0.0006 0.0004
Brugia malayi MH1 domain containing protein 0.0041 0.0066 0.0127
Brugia malayi gonadotropin-releasing hormone receptor 2 0.0135 0.0351 0.0704
Trypanosoma cruzi tubulin gamma chain 0.0938 0.28 0.5626
Onchocerca volvulus 0.0049 0.0089 0.0585
Echinococcus granulosus multidrug resistance protein 1 0.0022 0.0006 0.0004
Entamoeba histolytica hypothetical protein 0.0025 0.0016 0.0019
Brugia malayi Ubiquitin carboxyl-terminal hydrolase family protein 0.0037 0.0054 0.0103
Leishmania major beta tubulin 0.1644 0.4949 1
Schistosoma mansoni organic anion transporter 0.0086 0.0202 0.0309
Echinococcus multilocularis tubulin beta 1 chain 0.1644 0.4949 0.4947
Trichomonas vaginalis PIKK family atypical protein kinase 0.0031 0.0035 0.0071
Brugia malayi hypothetical protein 0.0086 0.0202 0.0402
Schistosoma mansoni intermediate filament proteins 0.0082 0.0191 0.0292
Echinococcus granulosus alpha tubulin 0.1253 0.3759 0.5929
Trichomonas vaginalis adenylate and guanylate cyclases, putative 0.0051 0.0098 0.0197
Brugia malayi nuclear hormone receptor family member odr-7 0.0025 0.0018 0.003
Loa Loa (eye worm) hypothetical protein 0.0059 0.0119 0.0165
Loa Loa (eye worm) nuclear hormone receptor 0.0025 0.0018 0.0021
Trypanosoma cruzi ubiquitin carboxyl-terminal hydrolase, putative 0.0037 0.0054 0.0039
Loa Loa (eye worm) nuclear hormone receptor family member nhr-40 0.0059 0.012 0.0168
Plasmodium falciparum alpha tubulin 1 0.1253 0.3759 0.7592
Giardia lamblia Beta tubulin 0.1644 0.4949 1
Schistosoma mansoni zinc finger protein 0.0025 0.0018 0.0018
Schistosoma mansoni nuclear hormone receptor superfamily protein-related 0.0025 0.0018 0.0018
Onchocerca volvulus 0.0242 0.0679 0.4617
Trichomonas vaginalis lipid A export ATP-binding/permease protein msba, putative 0.0022 0.0006 0.0013
Loa Loa (eye worm) tubulin alpha 2 0.0843 0.251 0.3574
Wolbachia endosymbiont of Brugia malayi dihydrolipoamide dehydrogenase E3 component 0.0033 0.0042 0.0276
Schistosoma mansoni peptide (FMRFamide/neurokinin-3)-like receptor 0.0135 0.0351 0.0545
Brugia malayi SPARC precursor 0.0059 0.0119 0.0235
Loa Loa (eye worm) ATP-dependent DNA helicase 0.0029 0.0029 0.0037
Schistosoma mansoni thyroid hormone receptor 0.0059 0.012 0.018
Trichomonas vaginalis adenylate cyclase, putative 0.0051 0.0098 0.0197
Onchocerca volvulus Dopamine\/Ecdysteroid receptor homolog 0.0135 0.0351 0.2379
Echinococcus granulosus raf serine:threonine protein kinase 0.0044 0.0076 0.0114
Trichomonas vaginalis chromodomain helicase DNA binding protein, putative 0.0019 0.000000000036275 0.000000000073297
Loa Loa (eye worm) 5-hydroxytryptamine 2C receptor 0.0135 0.0351 0.0497
Brugia malayi nuclear receptor NHR-88 0.0025 0.0018 0.003
Loa Loa (eye worm) tubulin alpha-2 chain 0.1253 0.3759 0.5355
Loa Loa (eye worm) hypothetical protein 0.0025 0.0018 0.0021
Schistosoma mansoni ancient conserved domain protein 2 (cyclin m2) 0.0135 0.0351 0.0545
Schistosoma mansoni nuclear hormone receptor 0.0025 0.0018 0.0018
Echinococcus granulosus smad 0.0041 0.0066 0.0098
Brugia malayi sulfakinin receptor protein 0.0135 0.0351 0.0704
Echinococcus granulosus biogenic amine 5HT receptor 0.0135 0.0351 0.0549
Loa Loa (eye worm) PXA domain-containing protein 0.0025 0.0016 0.0018
Brugia malayi Tyrosyl-DNA phosphodiesterase family protein 0.0066 0.0143 0.0283
Leishmania major target of rapamycin kinase (TOR) kinase 3 0.0073 0.0164 0.032
Schistosoma mansoni aminoadipate-semialdehyde dehydrogenase 0.0081 0.0186 0.0284
Schistosoma mansoni aldehyde dehydrogenase 0.0062 0.0128 0.0192
Echinococcus granulosus mitogen activated protein kinase 0.0103 0.0256 0.0398
Plasmodium vivax holo-[acyl-carrier-protein] synthase, putative 0.0023 0.001 0.0007
Brugia malayi Tubulin gamma chain 0.0938 0.28 0.5655
Schistosoma mansoni hypothetical protein 0.0046 0.0081 0.0118
Echinococcus multilocularis regulator of G protein signaling 0.0025 0.0016 0.0012
Schistosoma mansoni aldehyde dehydrogenase 0.0062 0.0128 0.0192
Onchocerca volvulus 0.0082 0.0191 0.1286
Plasmodium vivax dihydrolipoyl dehydrogenase, apicoplast, putative 0.0033 0.0042 0.0073
Trichomonas vaginalis lipid A export ATP-binding/permease protein msba, putative 0.0022 0.0006 0.0013
Schistosoma mansoni regulator of G protein signaling 3 rgs3 0.0025 0.0016 0.0015
Trypanosoma brucei alpha tubulin 0.1253 0.3759 0.7591
Echinococcus multilocularis Tubulin beta 2C chain 0.1644 0.4949 0.4947
Echinococcus multilocularis neuropeptides capa receptor 0.0135 0.0351 0.0348
Echinococcus granulosus lysine specific demethylase 5A 0.0064 0.0136 0.0209
Loa Loa (eye worm) hypothetical protein 0.0025 0.0018 0.0021
Brugia malayi Dopamine receptor protein 2 0.0135 0.0351 0.0704
Trichomonas vaginalis guanylate cyclase, putative 0.0051 0.0098 0.0197
Echinococcus multilocularis aryl hydrocarbon receptor 0.0051 0.0098 0.0094
Loa Loa (eye worm) nuclear hormone receptor family member nhr-14 0.0059 0.012 0.0168
Mycobacterium ulcerans dihydrolipoamide dehydrogenase 0.0033 0.0042 0.0332
Brugia malayi Nuclear hormone receptor-like 1 0.0059 0.012 0.0238
Echinococcus multilocularis tubulin alpha 0.0911 0.2716 0.2713
Brugia malayi G protein-coupled receptor 0.0135 0.0351 0.0704
Mycobacterium ulcerans flavoprotein disulfide reductase 0.0033 0.0042 0.0332
Trypanosoma brucei phosphatidylinositol 4-kinase, putative 0.0092 0.0222 0.0429
Trypanosoma brucei dihydrolipoyl dehydrogenase 0.0033 0.0042 0.0066
Plasmodium vivax tubulin epsilon chain, putative 0.0938 0.2799 0.5649
Echinococcus granulosus Niemann Pick C1 protein 0.0284 0.0807 0.1268
Mycobacterium ulcerans 4'-phosphopantetheinyl transferase 0.0023 0.001 0.0057
Treponema pallidum NADH oxidase 0.0033 0.0042 0.0276
Brugia malayi regulator of G-protein signaling egl-10 0.0025 0.0016 0.0026
Echinococcus multilocularis expressed conserved protein 0.0187 0.051 0.0506
Trypanosoma brucei cytochrome P450, putative 0.0053 0.0103 0.0188
Echinococcus granulosus neuropeptides capa receptor 0.0135 0.0351 0.0549
Schistosoma mansoni ecdysone-induced protein 78c (dr-78) 0.0034 0.0043 0.0059
Loa Loa (eye worm) nuclear hormone receptor family member nhr-49 0.0059 0.012 0.0168
Leishmania major C-8 sterol isomerase-like protein 0.0782 0.2325 0.4691
Trichomonas vaginalis tubulin epsilon chain, putative 0.041 0.119 0.2404
Schistosoma mansoni serine/threonine protein kinase 0.0044 0.0076 0.011
Echinococcus granulosus ubiquitin specific protease 41 0.0037 0.0054 0.008
Trypanosoma cruzi cytochrome P450, putative 0.0053 0.0103 0.0138
Echinococcus multilocularis Aryl hydrocarbon receptor nuclear 0.0051 0.0098 0.0094
Leishmania major target of rapamycin (TOR) kinase 2, putative 0.0092 0.0222 0.0435
Loa Loa (eye worm) hypothetical protein 0.0059 0.0119 0.0165
Trichomonas vaginalis multidrug resistance protein 1, 2, putative 0.0022 0.0006 0.0013
Toxoplasma gondii 4'-phosphopantetheinyl transferase domain-containing protein 0.0023 0.001 0.0007
Echinococcus multilocularis neuropeptide receptor 0.0135 0.0351 0.0348
Entamoeba histolytica tubulin family protein 0.1644 0.4949 1
Echinococcus granulosus bloom syndrome protein 0.0042 0.0067 0.0101
Trichomonas vaginalis tubulin alpha-1 chain, putative 0.0843 0.251 0.5072
Echinococcus multilocularis ecdysone induced protein 78C 0.0059 0.012 0.0117
Leishmania major alpha tubulin 0.1253 0.3759 0.7592
Leishmania major protein kinase, putative 0.0052 0.01 0.019
Echinococcus granulosus 7tm_1 domain containing protein 0.0135 0.0351 0.0549
Trichomonas vaginalis DNA helicase recq, putative 0.0042 0.0067 0.0136
Brugia malayi Tubulin beta-1 chain 0.1644 0.4949 1
Plasmodium vivax tubulin gamma chain, putative 0.0938 0.28 0.5652
Loa Loa (eye worm) hypothetical protein 0.0059 0.012 0.0168
Plasmodium vivax SET domain protein, putative 0.0063 0.0133 0.0256
Mycobacterium tuberculosis Probable oxidoreductase 0.0244 0.0684 0.5742
Echinococcus granulosus Transcription factor JmjC domain containing protein 0.0059 0.0121 0.0185
Trypanosoma brucei phosphatidylinositol 3-kinase tor, putative 0.0044 0.0074 0.0129
Brugia malayi Cytochrome P450 family protein 0.0053 0.0103 0.0202
Loa Loa (eye worm) G-protein coupled receptor 0.0135 0.0351 0.0497
Brugia malayi MAP kinase sur-1 0.0103 0.0256 0.0511
Echinococcus multilocularis retinoic acid receptor rxr beta a retinoic acid receptor rxr alpha a retinoic acid receptor rxr alpha 0.0025 0.0018 0.0014
Giardia lamblia Pyrophosphate-fructose 6-phosphate 1-phosphotransferase alpha subunit 0.003 0.0033 0.0008
Trichomonas vaginalis set domain proteins, putative 0.0488 0.1427 0.2883
Brugia malayi tubulin alpha chain - mouse 0.1253 0.3759 0.7594
Trypanosoma brucei tubulin delta chain 0.058 0.1709 0.3441
Schistosoma mansoni nuclear receptor 0.0025 0.0018 0.0018
Mycobacterium tuberculosis Probable endonuclease IV End (endodeoxyribonuclease IV) (apurinase) 0.0078 0.0177 0.147
Echinococcus multilocularis agrin 0.0059 0.0119 0.0115
Trypanosoma cruzi zeta tubulin, putative 0.0695 0.2059 0.4118
Echinococcus multilocularis Basic leucine zipper (bZIP) transcription 0.0146 0.0387 0.0383
Brugia malayi hypothetical protein 0.0034 0.0043 0.0082
Loa Loa (eye worm) hypothetical protein 0.0086 0.0202 0.0283
Echinococcus multilocularis neuropeptide receptor 0.0135 0.0351 0.0348
Echinococcus multilocularis fmrfamide receptor 0.0135 0.0351 0.0348
Echinococcus multilocularis Basic leucine zipper (bZIP) transcription factor 0.0171 0.0462 0.0458
Trichomonas vaginalis PIKK family atypical protein kinase 0.0055 0.0109 0.0219
Schistosoma mansoni Tr4/Tr2 (homologue) 0.0059 0.012 0.018
Leishmania major protein kinase, putative 0.0052 0.01 0.019
Brugia malayi Tubulin alpha chain 0.1253 0.3759 0.7594
Trichomonas vaginalis soluble guanylate cyclase gcy, putative 0.0051 0.0098 0.0197
Schistosoma mansoni amine GPCR 0.0135 0.0351 0.0545
Schistosoma mansoni biogenic amine (5HT) receptor 0.0135 0.0351 0.0545
Leishmania major phosphatidylinositol 3-related kinase, putative 0.0031 0.0035 0.0058
Leishmania major mitogen activated protein kinase, putative,map kinase, putative 0.0103 0.0256 0.0504
Onchocerca volvulus Huntingtin homolog 0.0249 0.0701 0.4766
Loa Loa (eye worm) RGS-3 protein 0.0025 0.0016 0.0018
Echinococcus granulosus Nuclear hormone receptor family member nhr 41 0.0059 0.012 0.0184
Echinococcus multilocularis dnaJ subfamily B 0.0826 0.2458 0.2455
Echinococcus granulosus tubulin gamma 1 chain 0.0938 0.28 0.4415
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0135 0.0351 0.0545
Plasmodium falciparum alpha tubulin 2 0.1253 0.3759 0.7592
Toxoplasma gondii 6-phosphofructokinase 0.003 0.0033 0.0053
Echinococcus granulosus sterol regulatory element binding protein 0.0085 0.0201 0.0311
Loa Loa (eye worm) hypothetical protein 0.0025 0.0018 0.0021
Echinococcus granulosus neuropeptide receptor A26 0.1064 0.3183 0.5019
Trypanosoma cruzi cytochrome P450, putative 0.0053 0.0103 0.0138
Echinococcus multilocularis allatostatin A receptor 0.0135 0.0351 0.0348
Loa Loa (eye worm) 6-phosphofructokinase 0.0112 0.0282 0.0397
Trichomonas vaginalis tubulin alpha-1 chain, putative 0.1253 0.3759 0.7595
Echinococcus granulosus expressed protein 0.0389 0.1126 0.1773
Treponema pallidum diphosphate--fructose-6-phosphate 1-phosphotransferase 0.003 0.0033 0.0195
Trichomonas vaginalis adenylate cyclase, type VII, putative 0.0051 0.0098 0.0197
Brugia malayi MH2 domain containing protein 0.0041 0.0066 0.0127
Loa Loa (eye worm) hypothetical protein 0.0025 0.0016 0.0018
Echinococcus multilocularis thyrotropin releasing hormone receptor 0.0135 0.0351 0.0348
Brugia malayi Regulator of G protein signaling domain containing protein 0.0025 0.0016 0.0026
Trichomonas vaginalis tubulin gamma chain, putative 0.1644 0.4949 1
Loa Loa (eye worm) hypothetical protein 0.0135 0.0351 0.0497
Loa Loa (eye worm) MH2 domain-containing protein 0.0602 0.1774 0.2525
Onchocerca volvulus 0.0501 0.1467 1
Echinococcus granulosus Nuclear hormone receptor HR96 0.0025 0.0018 0.0022
Onchocerca volvulus 0.0022 0.0006 0.0023
Leishmania major beta tubulin 0.1644 0.4949 1
Loa Loa (eye worm) hypothetical protein 0.0135 0.0351 0.0497
Loa Loa (eye worm) hypothetical protein 0.0059 0.012 0.0168
Echinococcus multilocularis Solute carrier organic anion transporter family 0.0086 0.0202 0.0198
Brugia malayi 6-phosphofructokinase 0.0112 0.0282 0.0565
Leishmania major gamma-tubulin 0.0938 0.28 0.5652
Onchocerca volvulus 0.0135 0.0351 0.2379
Echinococcus multilocularis expressed protein 0.0059 0.0119 0.0115
Echinococcus multilocularis cytoplasmic intermediate filament protein 0.004 0.0062 0.0058
Plasmodium vivax tubulin beta chain, putative 0.1644 0.4949 1
Trichomonas vaginalis PIKK family atypical protein kinase 0.0025 0.0016 0.0033
Echinococcus multilocularis thyroid hormone receptor alpha 0.0059 0.012 0.0117
Echinococcus multilocularis Niemann Pick C1 protein 0.0284 0.0807 0.0803
Trypanosoma brucei beta tubulin 0.1644 0.4949 1
Schistosoma mansoni peptide (allatostatin)-like receptor 0.0135 0.0351 0.0545
Echinococcus multilocularis phosphatidylinositol 3 and 4 kinase 0.0031 0.0035 0.0031
Loa Loa (eye worm) hypothetical protein 0.0135 0.0351 0.0497
Schistosoma mansoni neuropeptide F-like receptor 0.0135 0.0351 0.0545
Echinococcus granulosus mixed lineage leukemia protein mll 0.0024 0.0013 0.0014
Brugia malayi MH1 domain containing protein 0.0041 0.0066 0.0127
Trypanosoma brucei alpha tubulin 0.1253 0.3759 0.7591
Schistosoma mansoni regulator of G protein signaling 17 19 20 (rgs17 19 20) 0.0025 0.0016 0.0015
Trichomonas vaginalis tubulin epsilon chain, putative 0.1644 0.4949 1
Leishmania major alpha tubulin 0.1253 0.3759 0.7592
Plasmodium falciparum tubulin gamma chain 0.0938 0.28 0.5652
Echinococcus multilocularis NADP dependent isocitrate dehydrogenase 0.0032 0.0038 0.0034
Echinococcus granulosus tubulin beta 1 chain 0.1644 0.4949 0.7808
Trypanosoma brucei C-8 sterol isomerase, putative 0.0782 0.2325 0.4687
Toxoplasma gondii Kazal-type serine protease inhibitor domain-containing protein 0.0059 0.0119 0.0228
Echinococcus multilocularis histone lysine methyltransferase setb histone lysine methyltransferase eggless 0.0063 0.0133 0.0129
Trypanosoma brucei ATP-dependent DEAD/H DNA helicase recQ, putative 0.0031 0.0037 0.0055
Brugia malayi ATP-dependent DNA helicase, RecQ family protein 0.0029 0.0029 0.0052
Echinococcus multilocularis tubulin alpha chain 0.1253 0.3759 0.3757
Loa Loa (eye worm) melatonin receptor type 1A 0.0135 0.0351 0.0497
Trichomonas vaginalis tubulin epsilon chain, putative 0.1644 0.4949 1
Entamoeba histolytica hypothetical protein 0.0025 0.0016 0.0019
Brugia malayi nuclear receptor NHR-88 0.0059 0.012 0.0238
Trichomonas vaginalis conserved hypothetical protein 0.0025 0.0016 0.0032
Brugia malayi PXA domain containing protein 0.0025 0.0016 0.0026
Trypanosoma cruzi C-8 sterol isomerase, putative 0.0782 0.2325 0.466
Echinococcus granulosus nuclear receptor subfamily 4 group A 0.0025 0.0018 0.0022
Loa Loa (eye worm) BEN-1 protein 0.1644 0.4949 0.7052
Loa Loa (eye worm) hypothetical protein 0.0034 0.0043 0.0058
Mycobacterium leprae PROBABLE NADH DEHYDROGENASE NDH 0.022 0.061 0.5113
Entamoeba histolytica phosphofructokinase, putative 0.0112 0.0282 0.0557
Echinococcus granulosus histone lysine N methyltransferase MLL3 0.0029 0.0029 0.0039
Trichomonas vaginalis fructose-bisphosphate aldolase, putative 0.0283 0.0804 0.1624
Trichomonas vaginalis tubulin, putative 0.0501 0.1467 0.2963
Brugia malayi hypothetical protein 0.0101 0.0249 0.0497
Trichomonas vaginalis tubulin beta chain, putative 0.1253 0.3759 0.7595
Loa Loa (eye worm) hypothetical protein 0.0025 0.0018 0.0021
Loa Loa (eye worm) hypothetical protein 0.0135 0.0351 0.0497
Onchocerca volvulus 0.0135 0.0351 0.2379
Echinococcus multilocularis NADP dependent isocitrate dehydrogenase 0.0032 0.0038 0.0034
Echinococcus multilocularis nuclear receptor subfamily 4 group A 0.0025 0.0018 0.0014
Echinococcus granulosus organic anion transporting polypeptide 30B 0.0086 0.0202 0.0313
Mycobacterium tuberculosis Probable isocitrate dehydrogenase [NADP] Icd1 (oxalosuccinate decarboxylase) (IDH) (NADP+-specific ICDH) (IDP) 0.0032 0.0038 0.0295
Loa Loa (eye worm) hypothetical protein 0.0135 0.0351 0.0497
Echinococcus granulosus Peptidase C19 ubiquitin carboxyl terminal hydrolase 2 0.0037 0.0054 0.008
Schistosoma mansoni cpg binding protein 0.0086 0.0202 0.0309
Brugia malayi F/Y-rich N-terminus family protein 0.0028 0.0027 0.005
Trichomonas vaginalis DNA helicase recq1, putative 0.0042 0.0067 0.0136
Loa Loa (eye worm) phosphofructokinase 0.0112 0.0282 0.0397
Trypanosoma brucei alpha tubulin 0.1253 0.3759 0.7591
Echinococcus granulosus rhodopsin orphan GPCR 0.0135 0.0351 0.0549
Trichomonas vaginalis CMGC family protein kinase 0.0103 0.0256 0.0517
Echinococcus granulosus A kinase anchor protein 10 mitochondrial 0.0025 0.0016 0.0019
Echinococcus granulosus neuropeptide Y receptor 0.0135 0.0351 0.0549
Trypanosoma brucei Phosphatidylinositol 3-kinase tor1 0.0092 0.0222 0.0429
Echinococcus multilocularis orexin receptor type 2 0.0135 0.0351 0.0348
Echinococcus multilocularis rhodopsin orphan GPCR 0.0135 0.0351 0.0348
Echinococcus multilocularis COUP TF:Svp nuclear hormone receptor 0.0059 0.012 0.0117
Echinococcus multilocularis tubulin alpha 1C chain 0.1253 0.3759 0.3757
Onchocerca volvulus Nuclear receptor subfamily 6 group A member 1 homolog 0.0025 0.0018 0.0101
Leishmania major alpha tubulin 0.1253 0.3759 0.7592
Brugia malayi Niemann-Pick C1 protein precursor 0.0199 0.0547 0.1099
Loa Loa (eye worm) hypothetical protein 0.0135 0.0351 0.0497
Echinococcus granulosus g protein coupled receptor 0.0135 0.0351 0.0549
Echinococcus granulosus Tubulin beta 2C chain 0.1644 0.4949 0.7808
Onchocerca volvulus Putative organic anion transporter 0.0086 0.0202 0.1359
Echinococcus granulosus tubulin epsilon chain 0.0938 0.2799 0.4413
Echinococcus granulosus biogenic amine 5HT receptor 0.0135 0.0351 0.0549
Onchocerca volvulus 0.0086 0.0202 0.1362
Echinococcus multilocularis hypothetical protein 0.1253 0.3759 0.3757
Echinococcus granulosus tubulin alpha 3 chain 0.1253 0.3759 0.5929
Trypanosoma cruzi mitogen activated protein kinase 4, putative 0.0103 0.0256 0.0449
Echinococcus multilocularis nuclear factor of activated T cells 5 0.0074 0.0167 0.0163
Toxoplasma gondii target of rapamycin (TOR), putative 0.0069 0.015 0.029
Schistosoma mansoni microtubule-associated protein tau 0.2099 0.6337 1
Entamoeba histolytica phosphatidylinositol3-kinaseTor2, putative 0.0092 0.0222 0.0435
Schistosoma mansoni myosin xvIII 0.0135 0.0351 0.0545
Trichomonas vaginalis PIKK family atypical protein kinase 0.0069 0.015 0.0302
Onchocerca volvulus 0.0082 0.0191 0.1286
Onchocerca volvulus Putative organic anion transporter 0.0086 0.0202 0.1359
Loa Loa (eye worm) isocitrate dehydrogenase 0.0032 0.0038 0.005
Loa Loa (eye worm) phosphatidylinositol 3 0.0031 0.0035 0.0046
Trichomonas vaginalis conserved hypothetical protein 0.0051 0.0098 0.0197
Echinococcus multilocularis regulator of G protein signaling 3 0.0025 0.0016 0.0012
Brugia malayi hypothetical protein 0.0249 0.0701 0.141
Leishmania major isocitrate dehydrogenase [NADP], mitochondrial precursor, putative 0.0032 0.0038 0.0064
Toxoplasma gondii alpha-tubulin I, putative 0.1253 0.3759 0.7592
Brugia malayi hypothetical protein 0.0135 0.0351 0.0704
Trypanosoma cruzi STE/STE11 serine/threonine-protein kinase, putative 0.0052 0.01 0.0133
Loa Loa (eye worm) hypothetical protein 0.0081 0.0186 0.0261
Loa Loa (eye worm) hypothetical protein 0.0081 0.0187 0.0262
Brugia malayi ecdysteroid receptor 0.0059 0.012 0.0238
Schistosoma mansoni biogenic amine (dopamine) receptor 0.0135 0.0351 0.0545
Mycobacterium leprae Possible regulatory protein 0.0051 0.0098 0.0797
Mycobacterium leprae PROBABLE 6-PHOSPHOFRUCTOKINASE PFKA (PHOSPHOHEXOKINASE) (PHOSPHOFRUCTOKINASE) 0.0112 0.0282 0.2348
Brugia malayi hypothetical protein 0.0103 0.0253 0.0506
Brugia malayi MH2 domain containing protein 0.0041 0.0066 0.0127
Brugia malayi hypoxia-induced factor 1 0.0613 0.1808 0.365
Onchocerca volvulus Neuropeptide F receptor homolog 0.0135 0.0351 0.2379
Loa Loa (eye worm) tubulin gamma chain 0.0938 0.28 0.3987
Loa Loa (eye worm) tubulin alpha chain 0.1253 0.3759 0.5355
Loa Loa (eye worm) raf kinase 0.0044 0.0076 0.0104
Trichomonas vaginalis lipid A export ATP-binding/permease protein msba, putative 0.0022 0.0006 0.0013
Loa Loa (eye worm) hypothetical protein 0.0025 0.0016 0.0018
Onchocerca volvulus 0.0086 0.0202 0.1359
Schistosoma mansoni retinoic acid receptor RXR 0.0059 0.012 0.018
Loa Loa (eye worm) hypothetical protein 0.0135 0.0351 0.0497
Echinococcus granulosus rhodopsin orphan GPCR 0.0135 0.0351 0.0549
Trypanosoma brucei tubulin gamma chain 0.0938 0.28 0.5649
Loa Loa (eye worm) transcription factor SMAD2 0.0602 0.1774 0.2525
Brugia malayi hypothetical protein 0.0066 0.0143 0.0282
Echinococcus multilocularis transfer RNA-Lys 0.0147 0.0387 0.0384
Trichomonas vaginalis PIKK family atypical protein kinase 0.0062 0.0129 0.0261
Echinococcus multilocularis mitogen activated protein kinase 3 0.0103 0.0256 0.0252
Brugia malayi Nuclear hormone receptor E75 0.0025 0.0018 0.003
Leishmania major beta tubulin 0.1644 0.4949 1
Loa Loa (eye worm) hypothetical protein 0.0135 0.0351 0.0497
Onchocerca volvulus 0.0025 0.0018 0.0101
Echinococcus multilocularis tm gpcr rhodopsin gpcr rhodopsin superfamily 0.0135 0.0351 0.0348
Echinococcus multilocularis neuropeptide FF receptor 2 0.0135 0.0351 0.0348
Leishmania major cytochrome p450-like protein 0.0053 0.0103 0.0195
Trichomonas vaginalis conserved hypothetical protein 0.0025 0.0016 0.0032
Trypanosoma brucei epsilon tubulin 0.0911 0.2716 0.5478
Trichomonas vaginalis phosphofructokinase, putative 0.0112 0.0282 0.0569
Echinococcus multilocularis 7TM GPCR, rhodopsin 0.0135 0.0351 0.0348
Trichomonas vaginalis lipid A export ATP-binding/permease protein msba, putative 0.0022 0.0006 0.0013
Loa Loa (eye worm) hypothetical protein 0.0086 0.0202 0.0283
Trypanosoma cruzi dihydrolipoamide dehydrogenase, putative 0.0033 0.0042 0.0015
Echinococcus multilocularis tm gpcr rhodopsin gpcr rhodopsin superfamily 0.0135 0.0351 0.0348
Mycobacterium leprae Probable fructose bisphosphate aldolase Fba 0.0138 0.0362 0.3028
Leishmania major alpha tubulin 0.1253 0.3759 0.7592
Onchocerca volvulus Putative organic anion transporter 0.0086 0.0202 0.1359
Echinococcus granulosus histone lysine N methyltransferase MLL3 0.0024 0.0013 0.0014
Echinococcus granulosus G protein coupled 5 hydroxytryptamine receptor 0.0135 0.0351 0.0549
Schistosoma mansoni neuropeptide F-like receptor 0.0135 0.0351 0.0545
Toxoplasma gondii aldehyde dehydrogenase 0.0062 0.0128 0.0247
Schistosoma mansoni opsin-like receptor 0.0135 0.0351 0.0545
Toxoplasma gondii histone lysine methyltransferase SET1 0.0165 0.0443 0.0884
Brugia malayi Pax transcription factor protein 2 0.0242 0.0679 0.1366
Echinococcus granulosus rhodopsin orphan GPCR 0.0135 0.0351 0.0549
Echinococcus granulosus orexin receptor type 2 0.0135 0.0351 0.0549
Onchocerca volvulus 0.0063 0.0133 0.0888
Plasmodium vivax multidomain scavenger receptor, putative 0.0101 0.0249 0.049
Schistosoma mansoni single-minded 0.0198 0.0544 0.085
Echinococcus multilocularis rhodopsin orphan GPCR 0.0135 0.0351 0.0348
Echinococcus multilocularis G protein coupled receptor 139 0.0135 0.0351 0.0348
Echinococcus granulosus axis inhibition protein axin 0.0025 0.0016 0.0019
Mycobacterium tuberculosis Cell division protein FtsZ 0.041 0.119 1
Schistosoma mansoni tubulin subunit delta 0.041 0.119 0.1869
Mycobacterium tuberculosis Dihydrolipoamide dehydrogenase LpdC (lipoamide reductase (NADH)) (lipoyl dehydrogenase) (dihydrolipoyl dehydrogenase) (diaphoras 0.0244 0.0684 0.5742
Schistosoma mansoni serine/threonine protein kinase 0.0103 0.0256 0.0394
Schistosoma mansoni hypothetical protein 0.0135 0.0351 0.0545
Brugia malayi hypothetical protein 0.0135 0.0351 0.0704
Schistosoma mansoni ubiquitin-specific peptidase 2 (C19 family) 0.0037 0.0054 0.0075
Trichomonas vaginalis PIKK family atypical protein kinase 0.005 0.0092 0.0187
Echinococcus multilocularis Transcription factor, JmjC domain containing protein 0.0059 0.0121 0.0117
Loa Loa (eye worm) hypothetical protein 0.0025 0.0018 0.0021
Schistosoma mansoni histone-lysine n-methyltransferase suv9 0.0063 0.0133 0.02
Loa Loa (eye worm) hypothetical protein 0.0059 0.0119 0.0165
Echinococcus multilocularis aldehyde dehydrogenase, mitochondrial 0.0062 0.0128 0.0125
Schistosoma mansoni hypothetical protein 0.0082 0.0191 0.0292
Echinococcus granulosus thioredoxin glutathione reductase 0.0096 0.0234 0.0364
Trichomonas vaginalis PIKK family atypical protein kinase 0.0031 0.0035 0.0071
Schistosoma mansoni nuclear receptor 2DBD-gamma 0.0059 0.012 0.018
Trypanosoma brucei PAB1-binding protein , putative 0.0103 0.0253 0.0493
Loa Loa (eye worm) hypothetical protein 0.0135 0.0351 0.0497
Trichomonas vaginalis multidrug resistance protein 1, 2, putative 0.0022 0.0006 0.0013
Onchocerca volvulus 0.0135 0.0351 0.2379
Entamoeba histolytica pyrophosphate-dependent phosphofructokinase 0.003 0.0033 0.0053
Brugia malayi Nuclear hormone receptor family member nhr-19 0.0059 0.012 0.0238
Loa Loa (eye worm) hypothetical protein 0.0082 0.0191 0.0268
Trypanosoma cruzi dihydrolipoamide dehydrogenase, putative 0.0033 0.0042 0.0015
Echinococcus multilocularis tubulin alpha 3 chain 0.1253 0.3759 0.3757
Echinococcus granulosus aldehyde dehydrogenase mitochondrial 0.0062 0.0128 0.0197
Brugia malayi hypothetical protein 0.0025 0.0016 0.0026
Trichomonas vaginalis lipid A export ATP-binding/permease protein msba, putative 0.0022 0.0006 0.0013
Loa Loa (eye worm) gonadotropin-releasing hormone receptor 2 0.0135 0.0351 0.0497
Loa Loa (eye worm) hypothetical protein 0.0135 0.0351 0.0497
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0135 0.0351 0.0545
Loa Loa (eye worm) aryl Hydrocarbon receptor Associated protein family member 0.0051 0.0098 0.0135
Plasmodium falciparum thioredoxin reductase 0.0096 0.0234 0.0461
Schistosoma mansoni follistatin 0.0059 0.0119 0.0178
Leishmania major phosphatidylinositol 3-kinase, putative 0.0031 0.0035 0.0058
Echinococcus granulosus follistatin 0.0059 0.0119 0.0182
Schistosoma mansoni neuropeptide receptor 0.0135 0.0351 0.0545
Schistosoma mansoni axis inhibition protein axin 0.0025 0.0016 0.0015
Schistosoma mansoni mixed-lineage leukemia protein mll 0.0184 0.0502 0.0783
Schistosoma mansoni hypothetical protein 0.0139 0.0364 0.0565
Schistosoma mansoni jumonji/arid domain-containing protein 0.0064 0.0136 0.0205
Brugia malayi hypothetical protein 0.0025 0.0018 0.003
Mycobacterium leprae PROBABLE ENDONUCLEASE IV END (ENDODEOXYRIBONUCLEASE IV) (APURINASE) 0.0078 0.0177 0.147
Schistosoma mansoni serine/threonine protein kinase 0.0026 0.0019 0.0019
Schistosoma mansoni neuropeptide receptor 0.0135 0.0351 0.0545
Leishmania major alpha tubulin 0.1253 0.3759 0.7592
Trypanosoma brucei alpha tubulin, putative 0.0501 0.1467 0.295
Echinococcus granulosus Tubulin alpha 1 chain 0.1253 0.3759 0.5929
Echinococcus granulosus beta tubulin 0.1644 0.4949 0.7808
Echinococcus multilocularis rhodopsin orphan GPCR 0.0135 0.0351 0.0348
Schistosoma mansoni alpha tubulin 0.1253 0.3759 0.5928
Schistosoma mansoni lamin 0.0082 0.0191 0.0292
Schistosoma mansoni cellular tumor antigen P53 0.0151 0.0402 0.0624
Toxoplasma gondii endonuclease IV APN 0.0078 0.0177 0.0346
Leishmania major dihydrolipoamide dehydrogenase, putative 0.0033 0.0042 0.0073
Plasmodium vivax glutathione reductase, putative 0.0096 0.0234 0.0461
Brugia malayi hypothetical protein 0.0025 0.0016 0.0026
Trypanosoma cruzi ATP-dependent DEAD/H DNA helicase recQ, putative 0.0031 0.0037 0.0004
Trichomonas vaginalis PIKK family atypical protein kinase 0.0073 0.0164 0.0332
Echinococcus granulosus rhodopsin orphan GPCR 0.0135 0.0351 0.0549
Trichomonas vaginalis phosphofructokinase, putative 0.003 0.0033 0.0066
Echinococcus granulosus multidrug resistance protein 1 0.0022 0.0006 0.0004
Echinococcus multilocularis FKBP12 rapamycin complex associated protein 0.0092 0.0222 0.0218
Schistosoma mansoni smad1 5 8 and 0.0041 0.0066 0.0094
Trichomonas vaginalis tubulin beta chain, putative 0.1253 0.3759 0.7595
Trichomonas vaginalis conserved hypothetical protein 0.0025 0.0016 0.0032
Entamoeba histolytica tubulin alpha chain, putative 0.1253 0.3759 0.7592
Echinococcus granulosus sex peptide receptor 0.0135 0.0351 0.0549
Echinococcus multilocularis tubulin alpha 3 chain 0.1253 0.3759 0.3757
Brugia malayi nuclear hormone receptor 0.0025 0.0018 0.003
Brugia malayi MH1 domain containing protein 0.0023 0.001 0.0014
Echinococcus multilocularis tubulin alpha chain 0.1253 0.3759 0.3757
Brugia malayi Pre-SET motif family protein 0.0063 0.0133 0.0263
Echinococcus multilocularis FTZ F1 alpha 0.0059 0.012 0.0117
Loa Loa (eye worm) hypothetical protein 0.0135 0.0351 0.0497
Echinococcus granulosus neuropeptide receptor 0.0135 0.0351 0.0549
Brugia malayi hypothetical protein 0.0135 0.0351 0.0704
Schistosoma mansoni opsin-like receptor 0.0135 0.0351 0.0545
Loa Loa (eye worm) agrin synaptic family protein 0.0059 0.0119 0.0165
Schistosoma mansoni thyrotropin-releasing hormone receptor 0.0135 0.0351 0.0545
Echinococcus granulosus tubulin alpha 0.0911 0.2716 0.4282
Plasmodium vivax delta tubulin, putative 0.041 0.119 0.2394
Echinococcus multilocularis lamin 0.0082 0.0191 0.0188
Echinococcus granulosus nuclear receptor 2DBD gamma 0.0059 0.012 0.0184
Echinococcus granulosus COUP TF:Svp nuclear hormone receptor 0.0059 0.012 0.0184
Trichomonas vaginalis abcb9, putative 0.0022 0.0006 0.0013
Schistosoma mansoni hypothetical protein 0.069 0.2043 0.3217
Leishmania major beta tubulin 0.1644 0.4949 1
Trichomonas vaginalis phosphofructokinase, putative 0.003 0.0033 0.0066
Echinococcus multilocularis nuclear receptor nhr 48 0.0025 0.0018 0.0014
Trichomonas vaginalis Clan CA, family C19, ubiquitin hydrolase-like cysteine peptidase 0.0037 0.0054 0.0109
Onchocerca volvulus 0.0135 0.0351 0.2379
Echinococcus granulosus Polycystic kidney disease protein 0.0101 0.0249 0.0387
Loa Loa (eye worm) hypothetical protein 0.0135 0.0351 0.0497
Loa Loa (eye worm) alpha-tubulin 0.1253 0.3759 0.5355
Echinococcus multilocularis nuclear receptor subfamily 1 group D 0.0034 0.0043 0.004
Echinococcus granulosus axis inhibition protein axin 0.0025 0.0016 0.0019
Giardia lamblia NADH oxidase lateral transfer candidate 0.0033 0.0042 0.0028
Plasmodium falciparum ataxin-2 like protein, putative 0.0103 0.0253 0.05
Brugia malayi hypothetical protein 0.0025 0.0018 0.003
Trichomonas vaginalis tubulin beta chain, putative 0.1253 0.3759 0.7595
Trypanosoma cruzi Phosphatidylinositol 3-kinase tor1 0.0092 0.0222 0.038
Plasmodium falciparum tubulin delta chain, putative 0.041 0.119 0.2394
Loa Loa (eye worm) hypothetical protein 0.0022 0.0006 0.0005
Brugia malayi AKH receptor 0.0135 0.0351 0.0704
Trichomonas vaginalis tubulin alpha-1 chain, putative 0.0501 0.1467 0.2963
Loa Loa (eye worm) multidrug resistance protein 3 0.0022 0.0006 0.0005
Brugia malayi A-kinase anchor protein 10, precursor 0.0025 0.0016 0.0026
Trichomonas vaginalis chromodomain helicase DNA binding protein, putative 0.0019 0.000000000036275 0.000000000073297
Mycobacterium ulcerans 6-phosphofructokinase 0.0112 0.0282 0.2348
Brugia malayi Regulator of G protein signaling domain containing protein 0.0025 0.0016 0.0026
Brugia malayi photoreceptor-specific nuclear receptor 0.0059 0.012 0.0238
Schistosoma mansoni loxhd1 0.0101 0.0249 0.0383
Echinococcus multilocularis histone lysine N methyltransferase SETMAR 0.0063 0.0133 0.0129
Schistosoma mansoni nuclear hormone receptor nor-1/nor-2 0.0059 0.012 0.018
Brugia malayi multidrug resistance protein 3 0.0022 0.0006 0.0007
Trypanosoma cruzi dihydrolipoamide dehydrogenase, putative 0.0033 0.0042 0.0015
Brugia malayi Ligand-binding domain of nuclear hormone receptor family protein 0.0059 0.012 0.0238
Trypanosoma brucei zeta tubulin, putative 0.0695 0.2059 0.4148
Loa Loa (eye worm) hypothetical protein 0.2322 0.7017 1
Echinococcus granulosus expressed conserved protein 0.0187 0.051 0.0799
Echinococcus multilocularis rhodopsin orphan GPCR 0.0135 0.0351 0.0348
Echinococcus granulosus tm gpcr rhodopsin 0.0135 0.0351 0.0549
Leishmania major beta tubulin 0.1644 0.4949 1
Toxoplasma gondii beta tubulin 0.1644 0.4949 1
Toxoplasma gondii alpha tubulin TUBA1 0.1253 0.3759 0.7592
Onchocerca volvulus Steroid hormone receptor family member cnr14 homolog 0.0059 0.012 0.0803
Trichomonas vaginalis PIKK family atypical protein kinase 0.0073 0.0164 0.0332
Echinococcus multilocularis nuclear receptor 2DBD gamma 0.0059 0.012 0.0117
Mycobacterium leprae cell division protein FtsZ 0.041 0.119 1
Loa Loa (eye worm) hypothetical protein 0.0101 0.0249 0.035
Schistosoma mansoni biogenic amine (octopamine/dopamine) receptor 0.0135 0.0351 0.0545
Leishmania major zeta tubulin, putative 0.0695 0.2059 0.4152
Echinococcus granulosus tubulin alpha chain 0.1253 0.3759 0.5929
Giardia lamblia Alpha-tubulin 0.1253 0.3759 0.7581
Loa Loa (eye worm) doublecortin family protein 0.0101 0.0249 0.035
Mycobacterium tuberculosis holo-[acyl-carrier protein] synthase AcpS (holo-ACP synthase) (CoA:APO-[ACP]pantetheinephosphotransferase) (CoA:APO-[acyl-carrie 0.0023 0.001 0.0057
Loa Loa (eye worm) kazal-type serine protease inhibitor domain-containing protein 0.0059 0.0119 0.0165
Echinococcus granulosus geminin 0.069 0.2043 0.322
Leishmania major alpha tubulin 0.1253 0.3759 0.7592
Echinococcus multilocularis Tubulin alpha 1 chain 0.1253 0.3759 0.3757
Loa Loa (eye worm) MH2 domain-containing protein 0.0041 0.0066 0.0089
Loa Loa (eye worm) tubulin beta chain 0.1644 0.4949 0.7052
Echinococcus granulosus tubulin subunit beta 0.1644 0.4949 0.7808
Trypanosoma cruzi alpha tubulin, putative 0.1253 0.3759 0.7578
Echinococcus multilocularis mitogen activated protein kinase 0.0103 0.0256 0.0252
Echinococcus multilocularis Tubulin beta 2C chain 0.1644 0.4949 0.4947
Echinococcus multilocularis tyrosyl DNA phosphodiesterase 1 0.0066 0.0143 0.0139
Brugia malayi Tubulin alpha chain 0.041 0.119 0.2399
Plasmodium falciparum glutathione reductase 0.0096 0.0234 0.0461
Chlamydia trachomatis two component regulatory system sensor histidine kinase 0.0051 0.0098 0.5329
Echinococcus multilocularis histone lysine N methyltransferase MLL3 0.0029 0.0029 0.0025
Loa Loa (eye worm) hypothetical protein 0.0086 0.0202 0.0283
Loa Loa (eye worm) G-protein coupled receptor 0.0135 0.0351 0.0497
Schistosoma mansoni tubulin subunit alpha 0.041 0.119 0.1869
Schistosoma mansoni transcription factor LCR-F1 0.0146 0.0387 0.0601
Loa Loa (eye worm) hypothetical protein 0.0059 0.0119 0.0165
Trichomonas vaginalis conserved hypothetical protein 0.041 0.119 0.2404
Echinococcus granulosus single minded 2 0.0147 0.0387 0.0606
Schistosoma mansoni regulator of G protein signaling 17 19 20 (rgs17 19 20) 0.0025 0.0016 0.0015
Trichomonas vaginalis fructose-bisphosphate aldolase, putative 0.0283 0.0804 0.1624
Loa Loa (eye worm) beta-tubulin 0.1644 0.4949 0.7052
Brugia malayi Nuclear hormone receptor family member nhr-49 0.0059 0.012 0.0238
Brugia malayi Dopamine receptor protein 1 0.0135 0.0351 0.0704
Trichomonas vaginalis PIKK family atypical protein kinase 0.0031 0.0035 0.0071
Echinococcus granulosus lamin 0.0082 0.0191 0.0296
Echinococcus multilocularis somatostatin receptor 0.0135 0.0351 0.0348
Treponema pallidum diphosphate--fructose-6-phosphate 1-phosphotransferase 0.0112 0.0282 0.2304
Trypanosoma cruzi beta tubulin, putative 0.1644 0.4949 1
Schistosoma mansoni biogenic amine (dopamine) receptor 0.0135 0.0351 0.0545
Echinococcus multilocularis fmrfamide receptor 0.0135 0.0351 0.0348
Trypanosoma brucei ATP-dependent 6-phosphofructokinase, glycosomal 0.0112 0.0282 0.055
Echinococcus multilocularis g protein linked acetylcholine receptor gar 2a 0.0135 0.0351 0.0348
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0135 0.0351 0.0545
Onchocerca volvulus 0.0135 0.0351 0.2379
Entamoeba histolytica hypothetical protein 0.0146 0.0387 0.077
Entamoeba histolytica fructose-1,6-bisphosphate aldolase, putative 0.0283 0.0804 0.1613
Loa Loa (eye worm) hypothetical protein 0.0025 0.0018 0.0021
Echinococcus multilocularis Tubulin beta 2C chain 0.1644 0.4949 0.4947
Echinococcus granulosus G protein coupled receptor 139 0.0135 0.0351 0.0549
Wolbachia endosymbiont of Brugia malayi dihydrolipoamide dehydrogenase E3 component 0.0033 0.0042 0.0276
Loa Loa (eye worm) BEN-1 protein 0.1644 0.4949 0.7052
Leishmania major acetoin dehydrogenase e3 component-like protein 0.0033 0.0042 0.0073
Trichomonas vaginalis ABC transporter, half transporter, putative 0.0022 0.0006 0.0013
Loa Loa (eye worm) hypothetical protein 0.0022 0.0006 0.0005
Echinococcus granulosus cytoplasmic intermediate filament protein 0.004 0.0062 0.0091
Toxoplasma gondii thioredoxin reductase 0.0096 0.0234 0.0461
Loa Loa (eye worm) hypothetical protein 0.0105 0.0259 0.0365
Trypanosoma brucei beta tubulin 0.1644 0.4949 1
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0135 0.0351 0.0545
Onchocerca volvulus 0.0135 0.0351 0.2379
Echinococcus multilocularis tubulin alpha chain 0.1253 0.3759 0.3757
Loa Loa (eye worm) hypothetical protein 0.0059 0.012 0.0168
Echinococcus multilocularis jun protein 0.0171 0.0462 0.0458
Toxoplasma gondii tubulin/FtsZ family, GTPase domain-containing protein 0.058 0.1709 0.3446
Brugia malayi hypothetical protein 0.0664 0.1965 0.3967
Echinococcus multilocularis dihydrolipoamide dehydrogenase 0.0033 0.0042 0.0039
Trichomonas vaginalis PIKK family atypical protein kinase 0.006 0.0123 0.0249
Brugia malayi PAS domain containing protein 0.0198 0.0544 0.1094
Loa Loa (eye worm) AGC/GRK/BARK protein kinase 0.0026 0.0019 0.0022
Trypanosoma cruzi PAB1-binding protein , putative 0.0103 0.0253 0.0445
Onchocerca volvulus 0.0081 0.0186 0.1252
Schistosoma mansoni tubulin subunit beta 0.1644 0.4949 0.7808
Schistosoma mansoni cpg binding protein 0.0091 0.0217 0.0333
Schistosoma mansoni regulator of G protein signaling 0.0025 0.0016 0.0015
Loa Loa (eye worm) hypothetical protein 0.0135 0.0351 0.0497
Trypanosoma cruzi tubulin delta chain 0.058 0.1709 0.3407
Chlamydia trachomatis fructose-6-phosphate phosphotransferase 0.003 0.0033 0.1545
Plasmodium vivax apurinic/apyrimidinic endonuclease Apn1, putative 0.0078 0.0177 0.0346
Brugia malayi Ligand-binding domain of nuclear hormone receptor family protein 0.0059 0.012 0.0238
Echinococcus granulosus peptide allatostatin:somatostatin 0.0135 0.0351 0.0549
Loa Loa (eye worm) nuclear Hormone Receptor family member 0.0059 0.012 0.0168
Echinococcus granulosus allatostatin A receptor 0.0135 0.0351 0.0549
Schistosoma mansoni alpha tubulin 0.1253 0.3759 0.5928
Echinococcus multilocularis regulator of G protein signaling 7 0.0025 0.0016 0.0012
Treponema pallidum fructose-bisphosphate aldolase 0.0283 0.0804 0.6728
Schistosoma mansoni serine/threonine protein kinase 0.0026 0.0019 0.0019
Trypanosoma brucei dihydrolipoamide dehydrogenase 0.0033 0.0042 0.0066
Loa Loa (eye worm) hypothetical protein 0.0135 0.0351 0.0497
Trypanosoma brucei phosphatidylinositol 3-related kinase, putative 0.0031 0.0035 0.0051
Echinococcus multilocularis tubulin alpha chain 0.1253 0.3759 0.3757
Schistosoma mansoni DNA helicase recq5 0.0029 0.0029 0.0035
Echinococcus granulosus regulator of G protein signaling 3 0.0025 0.0016 0.0019
Echinococcus granulosus tyrosyl DNA phosphodiesterase 1 0.0066 0.0143 0.022
Trypanosoma cruzi STE group serine/threonine-protein kinase, putative 0.0052 0.01 0.0133
Leishmania major delta tubulin, putative 0.058 0.1709 0.3446
Leishmania major epsilon tubulin, putative 0.0938 0.2799 0.5649
Brugia malayi Dopamine receptor protein 1, putative (partial) 0.0135 0.0351 0.0704
Brugia malayi Nuclear hormone receptor family member nhr-3 0.0059 0.012 0.0238
Loa Loa (eye worm) AGC/GRK/GRK protein kinase 0.0026 0.0019 0.0022
Brugia malayi Iron-sulfur cluster assembly accessory protein 0.0049 0.0089 0.0173
Brugia malayi ORL1-like opioid receptor 0.0135 0.0351 0.0704
Loa Loa (eye worm) hypothetical protein 0.0135 0.0351 0.0497
Trichomonas vaginalis fructose-bisphosphate aldolase, putative 0.0283 0.0804 0.1624
Echinococcus multilocularis arachidonate 5 lipoxygenase 0.0412 0.1195 0.1192
Schistosoma mansoni retinoid-x-receptor (RXR) 0.0059 0.012 0.018
Echinococcus multilocularis neuropeptide s receptor 0.1064 0.3183 0.318
Echinococcus multilocularis Nuclear hormone receptor HR96 0.0025 0.0018 0.0014
Loa Loa (eye worm) hypothetical protein 0.004 0.0062 0.0084
Loa Loa (eye worm) hypothetical protein 0.0135 0.0351 0.0497
Schistosoma mansoni FTZ-F1 nuclear receptor-like protein 0.0059 0.012 0.018
Echinococcus granulosus g protein linked acetylcholine receptor gar 2a 0.0135 0.0351 0.0549
Schistosoma mansoni agrin 0.0059 0.0119 0.0178
Brugia malayi phosphofructokinase 0.0112 0.0282 0.0563
Brugia malayi jmjC domain containing protein 0.0059 0.0121 0.0239
Leishmania major alpha tubulin 0.1253 0.3759 0.7592
Echinococcus multilocularis protein patched 0.0085 0.0201 0.0197
Schistosoma mansoni regulator of G protein signaling 0.0026 0.0019 0.002
Schistosoma mansoni neuropeptide receptor 0.0135 0.0351 0.0545
Brugia malayi dihydrolipoyl dehydrogenase, mitochondrial precursor, putative 0.0033 0.0042 0.008
Echinococcus multilocularis TGF beta signal transducer SmadC 0.0041 0.0066 0.0062
Echinococcus multilocularis neuropeptide receptor A26 0.1064 0.3183 0.318
Loa Loa (eye worm) pax transcription factor protein 2 0.0242 0.0679 0.0963
Loa Loa (eye worm) hypothetical protein 0.0086 0.0202 0.0283
Trypanosoma brucei epsilon tubulin 0.0938 0.2799 0.5646
Trichomonas vaginalis tubulin beta chain, putative 0.1644 0.4949 1
Trichomonas vaginalis multidrug resistance protein 1, 2, putative 0.0022 0.0006 0.0013
Leishmania major alpha tubulin 0.1253 0.3759 0.7592
Trichomonas vaginalis CMGC family protein kinase 0.0103 0.0256 0.0517
Trichomonas vaginalis PIKK family atypical protein kinase 0.0069 0.015 0.0302
Mycobacterium tuberculosis Probable membrane NADH dehydrogenase NdhA 0.022 0.061 0.5113
Echinococcus multilocularis axis inhibition protein axin 0.0025 0.0016 0.0012
Echinococcus granulosus survival motor neuron protein 1 0.0238 0.0666 0.1045
Loa Loa (eye worm) 6-phosphofructokinase 0.0112 0.0282 0.0397
Echinococcus granulosus nuclear receptor nhr 48 0.0025 0.0018 0.0022
Schistosoma mansoni hypothetical protein 0.0135 0.0351 0.0545
Brugia malayi PXA domain containing protein 0.0025 0.0016 0.0026
Schistosoma mansoni rab6-interacting 0.0101 0.0249 0.0383
Echinococcus multilocularis NADP dependent isocitrate dehydrogenase 0.0032 0.0038 0.0034
Echinococcus multilocularis protein dispatched 1 0.0097 0.0238 0.0234
Trichomonas vaginalis PIKK family atypical protein kinase 0.0069 0.015 0.0302
Brugia malayi hypothetical protein 0.0034 0.0043 0.0082
Echinococcus multilocularis microtubule associated protein 2 0.2099 0.6337 0.6336
Loa Loa (eye worm) TYRA-2 protein 0.0135 0.0351 0.0497
Echinococcus multilocularis dro:myosuppressin receptor 0.0135 0.0351 0.0348
Schistosoma mansoni tubulin subunit beta 0.1644 0.4949 0.7808
Trypanosoma cruzi mitogen activated protein kinase 2, putative 0.0103 0.0256 0.0449
Trichomonas vaginalis tubulin gamma chain, putative 0.041 0.119 0.2404
Echinococcus granulosus tubulin alpha chain 0.1253 0.3759 0.5929
Schistosoma mansoni tubulin subunit gamma 0.0938 0.28 0.4412
Leishmania major beta tubulin 0.1644 0.4949 1
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0135 0.0351 0.0545
Mycobacterium tuberculosis Probable aldehyde dehydrogenase 0.0062 0.0128 0.1056
Brugia malayi Nuclear hormone receptor-like 1 0.0034 0.0043 0.0082
Plasmodium vivax dihydrolipoyl dehydrogenase, mitochondrial, putative 0.0033 0.0042 0.0073
Chlamydia trachomatis holo [acyl-carrier protein] synthase 0.0023 0.001 0.0197
Echinococcus multilocularis isocitrate dehydrogenase 0.0032 0.0038 0.0034
Plasmodium falciparum ATP-dependent 6-phosphofructokinase 0.003 0.0033 0.0053
Echinococcus granulosus dnaJ subfamily B 0.0826 0.2458 0.3875
Loa Loa (eye worm) hypothetical protein 0.0103 0.0253 0.0357
Onchocerca volvulus 0.0059 0.0119 0.0793
Chlamydia trachomatis dihydrolipoyl dehydrogenase 0.0033 0.0042 0.2102
Schistosoma mansoni DNA helicase recq1 0.0029 0.0029 0.0035
Schistosoma mansoni histamine-responsive GPCR (AAF21638) 0.0135 0.0351 0.0545
Echinococcus granulosus lipoxygenase domain containing protein 0.0101 0.0249 0.0387
Plasmodium vivax ADP-dependent DNA helicase RecQ, putative 0.0025 0.0016 0.002
Trichomonas vaginalis ABC transporter, half transporter, putative 0.0022 0.0006 0.0013
Loa Loa (eye worm) hypothetical protein 0.0034 0.0043 0.0058
Trichomonas vaginalis fructose-bisphosphate aldolase, putative 0.0283 0.0804 0.1624
Brugia malayi Kazal-type serine protease inhibitor domain containing protein 0.0059 0.0119 0.0235
Schistosoma mansoni histone-lysine n-methyltransferase setb1 0.0063 0.0133 0.02
Trichomonas vaginalis tubulin alpha chain, putative 0.1644 0.4949 1
Trichomonas vaginalis chromodomain-helicase-DNA-binding protein, putative 0.0019 0.000000000036275 0.000000000073297
Echinococcus granulosus RUN 0.0101 0.0249 0.0387
Brugia malayi Cytochrome P450 family protein 0.0053 0.0103 0.0202
Echinococcus granulosus Tubulin alpha 1 chain 0.1253 0.3759 0.5929
Trypanosoma cruzi zeta tubulin, putative 0.0695 0.2059 0.4118
Trichomonas vaginalis Clan CA, family C19, ubiquitin hydrolase-like cysteine peptidase 0.0037 0.0054 0.0109
Echinococcus granulosus thyroid hormone receptor alpha 0.0025 0.0018 0.0022
Echinococcus multilocularis tubulin epsilon chain 0.0938 0.2799 0.2796
Brugia malayi hypothetical protein 0.0135 0.0351 0.0704
Loa Loa (eye worm) hypothetical protein 0.0151 0.0402 0.0568
Loa Loa (eye worm) hypothetical protein 0.0135 0.0351 0.0497
Trichomonas vaginalis guanylate cyclase, putative 0.0051 0.0098 0.0197
Plasmodium falciparum ATP-dependent 6-phosphofructokinase 0.003 0.0033 0.0053
Mycobacterium ulcerans fructose-bisphosphate aldolase 0.0138 0.0362 0.3028
Trichomonas vaginalis conserved hypothetical protein 0.0051 0.0098 0.0197
Loa Loa (eye worm) alpha-tubulin isotype 2 0.0843 0.251 0.3574
Loa Loa (eye worm) hypothetical protein 0.0063 0.0133 0.0185
Trichomonas vaginalis DNA helicase recq, putative 0.0031 0.0037 0.0074
Echinococcus granulosus tubulin alpha chain 0.1253 0.3759 0.5929
Mycobacterium ulcerans endonuclease IV 0.0078 0.0177 0.147
Onchocerca volvulus Bile acid receptor homolog 0.0059 0.012 0.0803
Loa Loa (eye worm) hypothetical protein 0.0037 0.0054 0.0073
Brugia malayi GnHR receptor homolog 0.0135 0.0351 0.0704
Echinococcus multilocularis RUN 0.0101 0.0249 0.0245
Brugia malayi Nuclear hormone receptor family member nhr-41 0.0059 0.012 0.0238
Loa Loa (eye worm) hypothetical protein 0.0843 0.251 0.3574
Brugia malayi Nuclear hormone receptor family member nhr-19 0.0059 0.012 0.0238
Echinococcus granulosus tubulin alpha 1C chain 0.1253 0.3759 0.5929
Toxoplasma gondii beta-1 tubulin, putative 0.1644 0.4949 1
Trichomonas vaginalis PIKK family atypical protein kinase 0.005 0.0092 0.0187
Brugia malayi larval opioid receptor 0.0135 0.0351 0.0704
Echinococcus granulosus hepatocyte nuclear factor 4 alpha 0.0059 0.012 0.0184
Mycobacterium ulcerans aldehyde dehydrogenase 0.0062 0.0128 0.1056
Leishmania major mitogen activated protein kinase 4, putative;with=GeneDB:LmxM19.1440 0.0103 0.0256 0.0504
Brugia malayi Nuclear hormone receptor family member nhr-25 0.0059 0.012 0.0238
Brugia malayi Nuclear hormone receptor family member nhr-14 0.0059 0.012 0.0238
Trypanosoma cruzi ATP-dependent 6-phosphofructokinase, glycosomal 0.0112 0.0282 0.0502
Echinococcus multilocularis Ataxin 2, N terminal,domain containing protein 0.0046 0.0081 0.0077
Schistosoma mansoni z-protein (S1r protein) 0.0025 0.0016 0.0015
Brugia malayi Nuclear hormone receptor family member nhr-31 0.0059 0.012 0.0238
Trichomonas vaginalis PIKK family atypical protein kinase 0.0031 0.0035 0.0071
Trichomonas vaginalis ABC transporter, putative 0.0022 0.0006 0.0013
Echinococcus multilocularis axis inhibition protein axin 0.0025 0.0016 0.0012
Giardia lamblia Kinase, CMGC MAPK 0.0103 0.0256 0.0461
Loa Loa (eye worm) hypothetical protein 0.0249 0.0701 0.0995
Schistosoma mansoni lamin 0.0082 0.0191 0.0292
Trichomonas vaginalis PIKK family atypical protein kinase 0.005 0.0092 0.0187
Trypanosoma brucei protein kinase, putative 0.0103 0.0256 0.0498
Echinococcus multilocularis multidrug resistance protein 1 0.0022 0.0006 0.0003
Loa Loa (eye worm) hypothetical protein 0.0249 0.0701 0.0995
Trichomonas vaginalis PIKK family atypical protein kinase 0.0069 0.015 0.0302
Loa Loa (eye worm) hypothetical protein 0.0135 0.0351 0.0497
Loa Loa (eye worm) tubulin beta chain 0.041 0.119 0.1692
Echinococcus granulosus pyroglutamylated rfamide peptide receptor 0.0135 0.0351 0.0549
Echinococcus multilocularis 6 phosphofructokinase 0.0112 0.0282 0.0278
Echinococcus multilocularis ATP binding cassette subfamily B (MDR:TAP) 0.0022 0.0006 0.0003
Echinococcus granulosus microtubule associated protein 2 0.2099 0.6337 1
Toxoplasma gondii transporter, major facilitator family protein 0.0086 0.0202 0.0395
Entamoeba histolytica hypothetical protein 0.0146 0.0387 0.077
Loa Loa (eye worm) hypothetical protein 0.0086 0.0202 0.0283
Trichomonas vaginalis PIKK family atypical protein kinase 0.0031 0.0035 0.0071
Brugia malayi Raf kinase 0.0044 0.0076 0.0148
Schistosoma mansoni 6-phosphofructokinase 0.0112 0.0282 0.0435
Toxoplasma gondii phosphofructokinase PFKII 0.003 0.0033 0.0053
Onchocerca volvulus Nuclear receptor subfamily 6 group A member 1 homolog 0.0025 0.0018 0.0101
Entamoeba histolytica recQ family helicase, putative 0.0031 0.0037 0.0061
Mycobacterium tuberculosis Probable NADH dehydrogenase Ndh 0.022 0.061 0.5113
Loa Loa (eye worm) hypothetical protein 0.0135 0.0351 0.0497
Plasmodium vivax 6-phosphofructokinase, putative 0.003 0.0033 0.0053
Brugia malayi hypothetical protein 0.0086 0.0202 0.0402
Loa Loa (eye worm) Smad1 0.0041 0.0066 0.0089
Schistosoma mansoni axis inhibition protein axin 0.0025 0.0016 0.0015
Schistosoma mansoni jumonji/arid domain-containing protein 0.0064 0.0136 0.0205
Brugia malayi Serotonin/octopamine receptor family protein 7 0.0135 0.0351 0.0704
Mycobacterium ulcerans dihydrolipoamide dehydrogenase, LpdB 0.0033 0.0042 0.0332
Trypanosoma brucei FAT domain/Rapamycin binding domain/Phosphatidylinositol 3- and 4-kinase, putative 0.0038 0.0057 0.0096
Schistosoma mansoni survival motor neuron protein 0.0049 0.0089 0.013
Schistosoma mansoni thyroid hormone receptor 0.0059 0.012 0.018
Echinococcus multilocularis Tubulin alpha 1 chain 0.1253 0.3759 0.3757
Trypanosoma cruzi isocitrate dehydrogenase [NADP], mitochondrial precursor, putative 0.0032 0.0038 0.0006
Trypanosoma cruzi STE/STE11 serine/threonine-protein kinase, putative 0.0052 0.01 0.0133
Echinococcus granulosus regulator of G protein signaling 3 0.0025 0.0016 0.0019
Plasmodium falciparum isocitrate dehydrogenase [NADP], mitochondrial 0.0032 0.0038 0.0064
Leishmania major beta tubulin 0.1644 0.4949 1
Echinococcus granulosus nuclear receptor subfamily 1 group D 0.0034 0.0043 0.0063
Trichomonas vaginalis PIKK family atypical protein kinase 0.005 0.0092 0.0187
Brugia malayi nuclear receptor NHR-67 0.0025 0.0018 0.003
Leishmania major PAS-domain containing phosphoglycerate kinase, putative 0.0051 0.0098 0.0184
Echinococcus multilocularis G-protein coupled receptor, putative 0.0135 0.0351 0.0348
Echinococcus granulosus Tubulin beta 2C chain 0.1644 0.4949 0.7808
Schistosoma mansoni jun-related protein 0.0139 0.0364 0.0565
Echinococcus multilocularis tubulin subunit TubB 0.1253 0.3759 0.3757
Wolbachia endosymbiont of Brugia malayi cell division protein FtsZ 0.041 0.119 1
Schistosoma mansoni hypothetical protein 0.0146 0.0387 0.0601
Brugia malayi Nuclear hormone receptor E75 0.0025 0.0018 0.003
Schistosoma mansoni amine GPCR 0.0135 0.0351 0.0545
Schistosoma mansoni biogenic amine receptor 0.0135 0.0351 0.0545
Trichomonas vaginalis ATP-binding cassette transporter, putative 0.0022 0.0006 0.0013
Echinococcus granulosus tm gpcr rhodopsin 0.0135 0.0351 0.0549
Schistosoma mansoni neuropeptide receptor 0.0135 0.0351 0.0545
Echinococcus multilocularis rhodopsin orphan GPCR 0.0135 0.0351 0.0348
Brugia malayi CXXC zinc finger family protein 0.0086 0.0202 0.0403
Brugia malayi bHLH-PAS transcription factor 0.0147 0.0387 0.0777
Trichomonas vaginalis 6-phosphofructokinase, putative 0.003 0.0033 0.0066
Plasmodium falciparum apurinic/apyrimidinic endonuclease Apn1, putative 0.0078 0.0177 0.0346
Brugia malayi prostaglandin transporter 0.0086 0.0202 0.0402
Echinococcus granulosus tubulin subunit TubB 0.1253 0.3759 0.5929
Echinococcus granulosus agrin 0.0059 0.0119 0.0182
Echinococcus multilocularis FTZ F1 nuclear receptor protein 0.0059 0.012 0.0117
Brugia malayi isocitrate dehydrogenase 0.0032 0.0038 0.0071
Loa Loa (eye worm) CYP4Cod1 0.0053 0.0103 0.0142
Brugia malayi follicle stimulating hormone receptor 0.037 0.1068 0.2152
Trichomonas vaginalis multidrug resistance protein 1, 2, putative 0.0022 0.0006 0.0013
Plasmodium falciparum dihydrolipoyl dehydrogenase, mitochondrial 0.0033 0.0042 0.0073
Schistosoma mansoni organic anion transporter 0.0086 0.0202 0.0309
Trypanosoma brucei mitogen activated protein kinase 4, putative 0.0103 0.0256 0.0498
Echinococcus granulosus neuropeptide Y receptor 0.0135 0.0351 0.0549
Entamoeba histolytica tubulin gamma chain 0.0938 0.28 0.5652
Giardia lamblia Ubiquitin carboxyl-terminal hydrolase 4 0.0037 0.0054 0.0052
Schistosoma mansoni hypothetical protein 0.0135 0.0351 0.0545
Loa Loa (eye worm) hypothetical protein 0.0135 0.0351 0.0497
Loa Loa (eye worm) hypothetical protein 0.0135 0.0351 0.0497
Brugia malayi hypothetical protein 0.0135 0.0351 0.0704
Trichomonas vaginalis chromodomain helicase DNA binding protein, putative 0.0019 0.000000000036275 0.000000000073297
Brugia malayi Kazal-type serine protease inhibitor domain containing protein 0.0059 0.0119 0.0235
Schistosoma mansoni nuclear hormone receptor 0.0059 0.012 0.018
Echinococcus multilocularis ATP binding cassette subfamily B (MDR:TAP) 0.0022 0.0006 0.0003
Echinococcus granulosus Nuclear hormone receptor HR96 0.0025 0.0018 0.0022
Echinococcus multilocularis Smad4 0.0041 0.0066 0.0062
Trichomonas vaginalis ABC transporter, putative 0.0022 0.0006 0.0013
Echinococcus multilocularis Nuclear hormone receptor HR96 0.0025 0.0018 0.0014
Brugia malayi conserved hypotetical protein 0.0025 0.0018 0.003
Echinococcus granulosus g protein coupled receptor 0.0135 0.0351 0.0549
Loa Loa (eye worm) alpha-tubulin 0.1253 0.3759 0.5355
Brugia malayi Nuclear hormone receptor-like 1 0.0034 0.0043 0.0082
Echinococcus multilocularis tubulin gamma 1 chain 0.0938 0.28 0.2797
Loa Loa (eye worm) hypothetical protein 0.0035 0.0048 0.0064
Echinococcus multilocularis regulator of G protein signaling 7 0.0025 0.0016 0.0012
Loa Loa (eye worm) intermediate filament protein 0.0082 0.0191 0.0268
Brugia malayi DNA-(Apurinic or apyrimidinic site) lyase 0.0078 0.0177 0.0353
Loa Loa (eye worm) hypothetical protein 0.0034 0.0043 0.0058
Schistosoma mansoni muscarinic acetylcholine (GAR) receptor 0.0135 0.0351 0.0545
Brugia malayi Nuclear hormone receptor family member nhr-40 0.0059 0.012 0.0238
Trypanosoma cruzi dihydrolipoamide dehydrogenase, putative 0.0033 0.0042 0.0015
Entamoeba histolytica tubulin alpha-1 chain 0.1253 0.3759 0.7592
Trypanosoma cruzi MFS transporter, putative 0.0086 0.0202 0.034
Echinococcus multilocularis expressed protein 0.0389 0.1126 0.1123
Trichomonas vaginalis adenylate and guanylate cyclases, putative 0.0051 0.0098 0.0197
Echinococcus multilocularis neuropeptides capa receptor 0.0135 0.0351 0.0348
Mycobacterium ulcerans cell division protein FtsZ 0.041 0.119 1
Brugia malayi regulator of G-protein signaling rgs-7 0.0025 0.0016 0.0026
Schistosoma mansoni dihydrolipoamide dehydrogenase 0.0033 0.0042 0.0057
Onchocerca volvulus 0.0086 0.0202 0.1359
Echinococcus granulosus neuropeptide s receptor 0.1064 0.3183 0.5019
Echinococcus granulosus fmrfamide receptor 0.0135 0.0351 0.0549
Echinococcus multilocularis ATP dependent DNA helicase Q5 0.0029 0.0029 0.0025
Trichomonas vaginalis ATP-binding cassette transporter, putative 0.0022 0.0006 0.0013
Trypanosoma brucei isocitrate dehydrogenase, putative 0.0032 0.0038 0.0057
Echinococcus multilocularis tachykinin peptides receptor 99D 0.0135 0.0351 0.0348
Echinococcus granulosus dihydrolipoamide dehydrogenase 0.0033 0.0042 0.0061
Brugia malayi 6-phosphofructokinase 0.0112 0.0282 0.0563
Onchocerca volvulus 0.0135 0.0351 0.2379
Plasmodium vivax isocitrate dehydrogenase [NADP], mitochondrial, putative 0.0032 0.0038 0.0064
Loa Loa (eye worm) hypothetical protein 0.0135 0.0351 0.0497
Giardia lamblia Beta tubulin 0.1644 0.4949 1
Schistosoma mansoni polycystin 1-related 0.0101 0.0249 0.0383
Echinococcus multilocularis rhodopsin orphan GPCR 0.0135 0.0351 0.0348
Brugia malayi nuclear hormone receptor 0.0059 0.012 0.0238
Brugia malayi aminoadipate-semialdehyde dehydrogenase-phosphopantetheinyl transferase 0.0081 0.0186 0.037
Loa Loa (eye worm) tubulin beta-1 chain 0.1644 0.4949 0.7052
Echinococcus granulosus rhodopsin orphan GPCR 0.0135 0.0351 0.0549
Mycobacterium tuberculosis Probable soluble pyridine nucleotide transhydrogenase SthA (STH) (NAD(P)(+) transhydrogenase [B-specific]) (nicotinamide nucleot 0.0033 0.0042 0.0332
Schistosoma mansoni tubulin subunit alpha 0.1253 0.3759 0.5928
Schistosoma mansoni tubulin subunit beta 0.1644 0.4949 0.7808
Trichomonas vaginalis PIKK family atypical protein kinase 0.005 0.0092 0.0186
Brugia malayi Nuclear hormone receptor family member nhr-25 0.0059 0.012 0.0238
Loa Loa (eye worm) hypothetical protein 0.0135 0.0351 0.0497
Loa Loa (eye worm) hypothetical protein 0.0135 0.0351 0.0497
Trichomonas vaginalis ABC transporter, putative 0.0022 0.0006 0.0013
Echinococcus granulosus ATP dependent DNA helicase Q1 0.0029 0.0029 0.0039
Echinococcus granulosus g protein coupled receptor 0.0135 0.0351 0.0549
Trichomonas vaginalis adenylate and guanylate cyclases, putative 0.0051 0.0098 0.0197
Echinococcus multilocularis G protein coupled 5 hydroxytryptamine receptor 0.0135 0.0351 0.0348
Entamoeba histolytica hypothetical protein 0.0146 0.0387 0.077
Echinococcus granulosus L aminoadipate semialdehyde 0.0081 0.0186 0.0288
Trichomonas vaginalis regulator of G protein signaling 5, rgs5, putative 0.0025 0.0016 0.0032
Brugia malayi nuclear receptor subfamily 1, group D, member 1, putative 0.0025 0.0018 0.003
Echinococcus multilocularis hepatocyte nuclear factor 4 alpha 0.0059 0.012 0.0117
Echinococcus granulosus tumor protein p63 0.1033 0.3089 0.4871
Trypanosoma brucei trypanothione reductase 0.0096 0.0234 0.0454
Plasmodium vivax 6-phosphofructokinase, putative 0.003 0.0033 0.0053
Echinococcus multilocularis beta tubulin 0.1644 0.4949 0.4947
Entamoeba histolytica hypothetical protein 0.0025 0.0016 0.0019
Echinococcus granulosus retinoic acid receptor rxr beta a 0.0059 0.012 0.0184
Trichomonas vaginalis PIKK family atypical protein kinase 0.0055 0.0109 0.0219
Schistosoma mansoni rab6-interacting 0.0101 0.0249 0.0383
Echinococcus granulosus NADP dependent isocitrate dehydrogenase 0.0032 0.0038 0.0054
Echinococcus granulosus ATP dependent DNA helicase Q5 0.0029 0.0029 0.0039
Echinococcus multilocularis Polycystic kidney disease protein 0.0101 0.0249 0.0245
Onchocerca volvulus 0.0059 0.012 0.0803
Schistosoma mansoni tubulin subunit beta 0.1644 0.4949 0.7808
Loa Loa (eye worm) hypothetical protein 0.0135 0.0351 0.0497
Schistosoma mansoni phosphatidylinositol 3-and 4-kinase 0.0031 0.0035 0.0045
Brugia malayi sodium-independent organic anion transporter family protein 0.0086 0.0202 0.0402
Echinococcus granulosus transcription factor Dp 1 0.0038 0.0058 0.0086
Trichomonas vaginalis taga, putative 0.0022 0.0006 0.0013
Trichomonas vaginalis tubulin alpha chain, putative 0.0501 0.1467 0.2963
Echinococcus granulosus Basic leucine zipper bZIP transcription 0.0146 0.0387 0.0605
Echinococcus granulosus regulator of G protein signaling 7 0.0025 0.0016 0.0019
Echinococcus multilocularis tubulin, beta 4A class IVa 0.1644 0.4949 0.4947
Schistosoma mansoni neuropeptide f receptor 76f 0.0135 0.0351 0.0545
Entamoeba histolytica fructose-1,6-bisphosphate aldolase, putative 0.0283 0.0804 0.1613
Echinococcus granulosus tubulin alpha 3 chain 0.1253 0.3759 0.5929
Echinococcus multilocularis g protein coupled receptor 0.0135 0.0351 0.0348
Trichomonas vaginalis lipid A export ATP-binding/permease protein msba, putative 0.0022 0.0006 0.0013
Loa Loa (eye worm) ATP-binding cassette sub-family B member 2 0.0022 0.0006 0.0005
Leishmania major hypothetical protein, conserved 0.0103 0.0253 0.05
Trichomonas vaginalis tubulin alpha-1 chain, putative 0.0752 0.2233 0.4512
Leishmania major alpha tubulin 0.1253 0.3759 0.7592
Loa Loa (eye worm) nuclear hormone receptor family member nhr-31 0.0059 0.012 0.0168
Schistosoma mansoni hypothetical protein 0.021 0.0581 0.0908
Echinococcus multilocularis g protein coupled receptor 0.0135 0.0351 0.0348
Giardia lamblia Beta tubulin 0.1644 0.4949 1
Trypanosoma brucei dihydrolipoamide dehydrogenase, point mutation 0.0033 0.0042 0.0066
Brugia malayi Kazal-type serine protease inhibitor domain containing protein 0.0059 0.0119 0.0235
Echinococcus granulosus neuropeptide receptor 0.0135 0.0351 0.0549
Toxoplasma gondii isocitrate dehydrogenase 0.0032 0.0038 0.0064
Giardia lamblia GTOR 0.0092 0.0222 0.0392
Trichomonas vaginalis tubulin beta chain, putative 0.1253 0.3759 0.7595
Trichomonas vaginalis ATP-binding cassette transporter, putative 0.0022 0.0006 0.0013
Loa Loa (eye worm) hypothetical protein 0.0025 0.0018 0.0021
Leishmania major beta tubulin 0.1644 0.4949 1
Echinococcus granulosus FTZ F1 alpha 0.0059 0.012 0.0184
Loa Loa (eye worm) hypoxia-induced factor 1 0.0613 0.1808 0.2574
Echinococcus granulosus beta-adrenergic receptor kinase 0.0026 0.0019 0.0024
Onchocerca volvulus 0.0086 0.0202 0.1359
Echinococcus multilocularis Tubulin beta 2C chain 0.1644 0.4949 0.4947
Echinococcus multilocularis beta adrenergic receptor kinase 0.0026 0.0019 0.0015
Trypanosoma cruzi Phosphatidylinositol 3-kinase tor2 0.0092 0.0222 0.038
Loa Loa (eye worm) hypothetical protein 0.0135 0.0351 0.0497
Loa Loa (eye worm) hypothetical protein 0.0025 0.0018 0.0021
Mycobacterium tuberculosis NAD(P)H quinone reductase LpdA 0.0244 0.0684 0.5742
Trichomonas vaginalis conserved hypothetical protein 0.0037 0.0054 0.0109
Brugia malayi tubulin alpha-2 chain 0.1253 0.3759 0.7594
Schistosoma mansoni nuclear hormone receptor 0.0025 0.0018 0.0018
Schistosoma mansoni histone-lysine n-methyltransferase setb1 0.0063 0.0133 0.02
Loa Loa (eye worm) tyrosyl-DNA phosphodiesterase 0.0066 0.0143 0.02
Brugia malayi jmjC domain containing protein 0.0064 0.0136 0.0269
Trypanosoma brucei beta tubulin 0.1644 0.4949 1
Echinococcus granulosus alpha 1A adrenergic receptor 0.0135 0.0351 0.0549
Brugia malayi Unidentified vitellogenin-linked transcript protein 6, putative 0.0135 0.0351 0.0704
Loa Loa (eye worm) hypothetical protein 0.0135 0.0351 0.0497
Trichomonas vaginalis tubulin beta chain, putative 0.0501 0.1467 0.2963
Schistosoma mansoni cpg binding protein 0.0091 0.0217 0.0333
Onchocerca volvulus 0.0135 0.0351 0.2379
Plasmodium falciparum ADP-dependent DNA helicase RecQ 0.0039 0.0059 0.0107
Trichomonas vaginalis tubulin, putative 0.1644 0.4949 1
Loa Loa (eye worm) hypothetical protein 0.0025 0.0018 0.0021
Echinococcus multilocularis tubulin alpha 1C chain 0.1253 0.3759 0.3757
Echinococcus granulosus ATP binding cassette subfamily B MDR:TAP 0.0022 0.0006 0.0004
Loa Loa (eye worm) hypothetical protein 0.0135 0.0351 0.0497
Trichomonas vaginalis PIKK family atypical protein kinase 0.0092 0.0222 0.0448
Loa Loa (eye worm) hypothetical protein 0.0135 0.0351 0.0497
Trichomonas vaginalis ATP-binding cassette transporter, putative 0.0022 0.0006 0.0013
Brugia malayi Cell division protein ftsZ 0.041 0.119 0.2399
Schistosoma mansoni biogenic amine receptor 0.0135 0.0351 0.0545
Echinococcus granulosus thyrotropin releasing hormone receptor 0.0135 0.0351 0.0549
Brugia malayi Tubulin alpha-2 chain 0.1253 0.3759 0.7594
Echinococcus multilocularis Peptidase C19, ubiquitin carboxyl terminal hydrolase 2 0.0037 0.0054 0.005
Echinococcus multilocularis raf serine:threonine protein kinase 0.0044 0.0076 0.0072
Loa Loa (eye worm) hypothetical protein 0.0135 0.0351 0.0497
Trichomonas vaginalis conserved hypothetical protein 0.0085 0.0201 0.0406
Trypanosoma brucei tyrosyl-DNA Phosphodiesterase (Tdp1), putative 0.0066 0.0143 0.027
Leishmania major beta tubulin 0.1644 0.4949 1
Loa Loa (eye worm) hypothetical protein 0.0086 0.0202 0.0283
Echinococcus granulosus nuclear receptor 2DBD gamma 0.0025 0.0018 0.0022
Brugia malayi putative neuropeptide receptor 0.0135 0.0351 0.0704
Echinococcus granulosus peroxisome assembly protein 26 0.1253 0.3759 0.5929
Loa Loa (eye worm) hypothetical protein 0.0027 0.0024 0.003
Loa Loa (eye worm) hypothetical protein 0.0051 0.0098 0.0135
Echinococcus multilocularis geminin 0.069 0.2043 0.204
Trypanosoma cruzi dihydrolipoyl dehydrogenase, putative 0.0033 0.0042 0.0015
Echinococcus multilocularis organic anion transporting polypeptide 30B 0.0086 0.0202 0.0198
Trichomonas vaginalis CMGC family protein kinase 0.0103 0.0256 0.0517
Onchocerca volvulus 0.0101 0.0249 0.1678
Schistosoma mansoni amine GPCR 0.0135 0.0351 0.0545
Schistosoma mansoni smad1 5 8 and 0.0041 0.0066 0.0094
Brugia malayi Tachykinin-like peptides receptor 99D 0.0135 0.0351 0.0704
Loa Loa (eye worm) jmjC domain-containing protein 0.0064 0.0136 0.019
Loa Loa (eye worm) glutathione reductase 0.0096 0.0234 0.0329
Echinococcus multilocularis Tubulin beta 2C chain 0.1644 0.4949 0.4947
Trichomonas vaginalis PIKK family atypical protein kinase 0.0073 0.0164 0.0332
Toxoplasma gondii phosphofructokinase domain-containing protein 0.003 0.0033 0.0053
Loa Loa (eye worm) hypothetical protein 0.0038 0.0057 0.0077
Brugia malayi Probable G protein-coupled receptor kinase F19C6.1, putative 0.0026 0.0019 0.0032
Echinococcus granulosus beta tubulin 0.1644 0.4949 0.7808
Schistosoma mansoni hepatocyte nuclear factor 4-alpha (hnf-4-alpha) 0.0025 0.0018 0.0018
Loa Loa (eye worm) intermediate filament tail domain-containing protein 0.0082 0.0191 0.0268
Leishmania major beta tubulin 0.1644 0.4949 1
Leishmania major alpha tubulin 0.1253 0.3759 0.7592
Loa Loa (eye worm) nuclear receptor nhr-7B 0.0025 0.0018 0.0021
Loa Loa (eye worm) hypothetical protein 0.0782 0.2325 0.331
Echinococcus multilocularis lipoxygenase domain containing protein 0.0101 0.0249 0.0245
Schistosoma mansoni alpha tubulin 0.1253 0.3759 0.5928
Brugia malayi orphan nuclear receptor NR2E1 0.0025 0.0018 0.003
Trichomonas vaginalis fructose-bisphosphate aldolase, putative 0.0283 0.0804 0.1624
Brugia malayi Kazal-type serine protease inhibitor domain containing protein 0.0059 0.0119 0.0235
Schistosoma mansoni adenoreceptor 0.0135 0.0351 0.0545
Brugia malayi hypothetical protein 0.0146 0.0387 0.0776
Echinococcus granulosus Solute carrier organic anion transporter family 0.0086 0.0202 0.0313
Trichomonas vaginalis conserved hypothetical protein 0.041 0.119 0.2404
Loa Loa (eye worm) hypothetical protein 0.0025 0.0018 0.0021
Loa Loa (eye worm) hypothetical protein 0.0135 0.0351 0.0497
Brugia malayi Pyridine nucleotide-disulphide oxidoreductase, dimerisation domain containing protein 0.0025 0.0015 0.0025
Trichomonas vaginalis phosphofructokinase, putative 0.003 0.0033 0.0066
Echinococcus granulosus mothers against decapentaplegic 5 0.0041 0.0066 0.0098
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0135 0.0351 0.0545
Trypanosoma cruzi dihydrolipoamide dehydrogenase, putative 0.0033 0.0042 0.0015
Echinococcus multilocularis A kinase anchor protein 10, mitochondrial 0.0025 0.0016 0.0012
Leishmania major beta tubulin 0.1644 0.4949 1
Echinococcus granulosus Tubulin beta 2C chain 0.1644 0.4949 0.7808
Leishmania major alpha tubulin 0.1253 0.3759 0.7592
Loa Loa (eye worm) MH1 domain-containing protein 0.0041 0.0066 0.0089
Echinococcus multilocularis peptide (allatostatin:somatostatin) 0.0135 0.0351 0.0348
Echinococcus multilocularis ubiquitin specific protease 41 0.0037 0.0054 0.005
Loa Loa (eye worm) cytoplasmic intermediate filament protein 0.0044 0.0075 0.0103
Echinococcus multilocularis Nuclear hormone receptor family member nhr 41 0.0059 0.012 0.0117
Echinococcus multilocularis L aminoadipate semialdehyde 0.0081 0.0186 0.0183
Trypanosoma cruzi mitogen-activated protein kinase 11, putative 0.0103 0.0256 0.0449
Onchocerca volvulus 0.0147 0.0387 0.2626
Brugia malayi CHE-14 protein 0.0085 0.0201 0.04
Trypanosoma brucei dihydrolipoamide dehydrogenase 0.0033 0.0042 0.0066
Echinococcus multilocularis multidrug resistance protein 1 0.0022 0.0006 0.0003
Loa Loa (eye worm) hypothetical protein 0.04 0.1159 0.1648
Loa Loa (eye worm) nuclear receptor NHR-67 0.0025 0.0018 0.0021
Loa Loa (eye worm) hypothetical protein 0.0023 0.001 0.001
Onchocerca volvulus 0.0134 0.035 0.2369
Loa Loa (eye worm) hypothetical protein 0.0135 0.0351 0.0497
Loa Loa (eye worm) hypothetical protein 0.0025 0.0016 0.0018
Echinococcus granulosus Regulator of G protein signaling 20 0.0025 0.0016 0.0019
Schistosoma mansoni niemann-pick C1 (NPC1) 0.0202 0.0556 0.0868
Brugia malayi Tubulin beta chain 0.041 0.119 0.2399
Echinococcus multilocularis g protein coupled receptor 0.0135 0.0351 0.0348
Echinococcus granulosus lipoxygenase domain containing protein 0.0101 0.0249 0.0387
Trichomonas vaginalis PIKK family atypical protein kinase 0.005 0.0092 0.0186
Echinococcus multilocularis cpg binding protein 0.0091 0.0217 0.0214
Loa Loa (eye worm) hypothetical protein 0.0101 0.0249 0.035
Schistosoma mansoni smad1 5 8 and 0.0041 0.0066 0.0094
Loa Loa (eye worm) G-protein-linked acetylcholine receptor protein 2 0.0135 0.0351 0.0497
Loa Loa (eye worm) hypothetical protein 0.0025 0.0016 0.0018
Toxoplasma gondii NADPH-glutathione reductase 0.0033 0.0042 0.0073
Mycobacterium tuberculosis NADPH-dependent mycothiol reductase Mtr 0.0096 0.0234 0.1947
Schistosoma mansoni hypothetical protein 0.0049 0.0089 0.013
Entamoeba histolytica ubiquitin carboxyl-terminal hydrolase domain containing protein 0.0037 0.0054 0.0097
Onchocerca volvulus 0.0135 0.0351 0.2379
Trypanosoma cruzi mitogen-activated protein kinase 11, putative 0.0103 0.0256 0.0449
Toxoplasma gondii isocitrate dehydrogenase 0.0032 0.0038 0.0064
Brugia malayi hypothetical protein 0.0238 0.0666 0.134
Loa Loa (eye worm) nuclear hormone receptor family member nhr-41 0.0059 0.012 0.0168
Echinococcus multilocularis Tubulin alpha 1 chain 0.1253 0.3759 0.3757
Brugia malayi ABC transporter family protein 0.0022 0.0006 0.0007
Schistosoma mansoni blooms syndrome DNA helicase 0.0027 0.0023 0.0026
Echinococcus granulosus phosphatidylinositol 3 and 4 kinase 0.0031 0.0035 0.0049
Trichomonas vaginalis tubulin gamma chain, putative 0.0938 0.28 0.5657
Plasmodium falciparum ATP-dependent DNA helicase Q1 0.0029 0.0029 0.0045
Echinococcus granulosus lamin dm0 0.0082 0.0191 0.0296
Entamoeba histolytica phosphofructokinase, putative 0.0112 0.0282 0.0557
Trypanosoma cruzi trypanothione reductase, putative 0.0033 0.0042 0.0015
Schistosoma mansoni biogenic amine (dopamine) receptor 0.0135 0.0351 0.0545
Loa Loa (eye worm) RecQ helicase 0.0042 0.0067 0.0092
Echinococcus multilocularis ATP binding cassette sub family B 0.0021 0.0006 0.0002
Loa Loa (eye worm) hypothetical protein 0.0025 0.0018 0.0021
Mycobacterium ulcerans cytochrome P450 185A4 Cyp185A4 0.0053 0.0103 0.084
Trichomonas vaginalis ABC transporter, putative 0.0022 0.0006 0.0013
Echinococcus granulosus hypothetical protein 0.0135 0.0351 0.0549
Toxoplasma gondii 4'-phosphopantetheinyl transferase superfamily protein 0.0023 0.001 0.0007
Echinococcus multilocularis transcription factor Dp 1 0.0038 0.0058 0.0054
Mycobacterium leprae DIHYDROLIPOAMIDE DEHYDROGENASE LPD (LIPOAMIDE REDUCTASE (NADH)) (LIPOYL DEHYDROGENASE) (DIHYDROLIPOYL DEHYDROGENASE) (DIAPHORASE 0.0244 0.0684 0.5742
Toxoplasma gondii ATP-dependent DNA helicase, RecQ family protein 0.0029 0.0029 0.0045
Mycobacterium tuberculosis Probable fructose-bisphosphate aldolase Fba 0.0138 0.0362 0.3028
Echinococcus multilocularis nuclear receptor 2DBD gamma 0.0025 0.0018 0.0014
Echinococcus multilocularis serotonin receptor 0.0135 0.0351 0.0348
Echinococcus multilocularis rhodopsin orphan GPCR 0.0135 0.0351 0.0348
Plasmodium falciparum thioredoxin reductase 0.0033 0.0042 0.0073
Schistosoma mansoni patched 1 0.0085 0.0201 0.0307
Echinococcus granulosus regulator of G protein signaling 7 0.0025 0.0016 0.0019
Toxoplasma gondii tubulin, putative 0.0027 0.0024 0.0035
Trichomonas vaginalis tubulin alpha chain, putative 0.0501 0.1467 0.2963
Mycobacterium ulcerans putative regulatory protein 0.0147 0.0387 0.3239
Leishmania major dihydrolipoamide dehydrogenase, putative 0.0033 0.0042 0.0073
Loa Loa (eye worm) follicle stimulating hormone receptor 0.037 0.1068 0.1518
Loa Loa (eye worm) steroid hormone receptor 0.0059 0.012 0.0168
Echinococcus multilocularis pyroglutamylated rfamide peptide receptor 0.0135 0.0351 0.0348
Brugia malayi Melatonin receptor type 1A 0.0135 0.0351 0.0704
Loa Loa (eye worm) nuclear hormone receptor-like 1 0.0034 0.0043 0.0058
Loa Loa (eye worm) CMGC/MAPK/ERK1 protein kinase 0.0103 0.0256 0.036
Brugia malayi sodium-independent organic anion transporter family protein 0.0086 0.0202 0.0402
Schistosoma mansoni regulator of G protein signaling 0.0025 0.0016 0.0015
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0135 0.0351 0.0545
Loa Loa (eye worm) tubulin alpha 2 0.0843 0.251 0.3574
Loa Loa (eye worm) hypothetical protein 0.0085 0.0201 0.0282
Leishmania major target of rapamycin (TOR) kinase 1, putative 0.0092 0.0222 0.0435
Echinococcus multilocularis smad 0.0041 0.0066 0.0062
Trichomonas vaginalis tubulin, putative 0.0438 0.1274 0.2574
Schistosoma mansoni tubulin subunit alpha 0.1253 0.3759 0.5928
Trypanosoma cruzi dihydrolipoamide dehydrogenase, putative 0.0033 0.0042 0.0015
Loa Loa (eye worm) nuclear hormone receptor family member nhr-1 0.0059 0.012 0.0168
Trichomonas vaginalis phosphofructokinase, putative 0.0112 0.0282 0.0569
Echinococcus granulosus histone lysine methyltransferase setb 0.0063 0.0133 0.0204
Echinococcus multilocularis lipoxygenase domain containing protein 0.0101 0.0249 0.0245
Echinococcus multilocularis g protein linked acetylcholine receptor gar 2a 0.0135 0.0351 0.0348
Echinococcus multilocularis bloom syndrome protein 0.0042 0.0067 0.0064
Schistosoma mansoni hypothetical protein 0.0082 0.0191 0.0292
Brugia malayi Pre-SET motif family protein 0.0429 0.1247 0.2516
Trichomonas vaginalis tubulin beta-1 chain, putative 0.041 0.119 0.2404
Echinococcus granulosus Tubulin beta 2C chain 0.1644 0.4949 0.7808
Onchocerca volvulus 0.0086 0.0202 0.1359
Echinococcus granulosus Aryl hydrocarbon receptor nuclear 0.0051 0.0098 0.0148
Trichomonas vaginalis fructose-bisphosphate aldolase, putative 0.0283 0.0804 0.1624
Trichomonas vaginalis PIKK family atypical protein kinase 0.0055 0.0107 0.0216
Brugia malayi Serotonin receptor 0.0135 0.0351 0.0704
Echinococcus granulosus serotonin receptor 0.0135 0.0351 0.0549
Brugia malayi secreted modular calcium-binding protein 1 0.0059 0.0119 0.0235
Onchocerca volvulus 0.0151 0.0402 0.2723
Schistosoma mansoni alpha-1 adrenergic receptor 0.0135 0.0351 0.0545
Trypanosoma brucei ubiquitin carboxyl-terminal hydrolase, putative 0.0037 0.0054 0.009
Schistosoma mansoni biogenic amine receptor 0.0135 0.0351 0.0545
Entamoeba histolytica phosphofructokinase, putative 0.0112 0.0282 0.0557
Trypanosoma cruzi ubiquitin carboxyl-terminal hydrolase, putative 0.0037 0.0054 0.0039
Echinococcus multilocularis Niemann Pick C1 protein 0.0199 0.0547 0.0543
Echinococcus granulosus Basic leucine zipper bZIP transcription factor 0.0171 0.0462 0.0723
Echinococcus multilocularis alpha 1A adrenergic receptor 0.0135 0.0351 0.0348
Echinococcus multilocularis neuropeptide Y receptor 0.0135 0.0351 0.0348
Brugia malayi nuclear receptor RXR 0.0025 0.0018 0.003
Onchocerca volvulus 0.0135 0.0351 0.2379
Trypanosoma cruzi isocitrate dehydrogenase, putative 0.0032 0.0038 0.0006
Toxoplasma gondii beta-tubulin, putative 0.1644 0.4949 1
Brugia malayi intermediate filament protein 0.0082 0.0191 0.0381
Echinococcus granulosus FKBP12 rapamycin complex associated protein 0.0092 0.0222 0.0344
Echinococcus granulosus ATP binding cassette subfamily B MDR:TAP 0.0022 0.0006 0.0004
Brugia malayi Bloom's syndrome protein homolog 0.0042 0.0067 0.013
Loa Loa (eye worm) G protein signaling regulator EGL-10 0.0025 0.0016 0.0018
Brugia malayi hypothetical protein 0.0135 0.0351 0.0704
Echinococcus multilocularis thioredoxin glutathione reductase 0.0096 0.0234 0.023
Trichomonas vaginalis tubulin epsilon chain, putative 0.1253 0.3759 0.7595
Echinococcus multilocularis Regulator of G protein signaling 20 0.0025 0.0016 0.0012
Loa Loa (eye worm) neuropeptide F receptor 0.0135 0.0351 0.0497
Brugia malayi neuropeptide F receptor 0.0135 0.0351 0.0704
Loa Loa (eye worm) hypothetical protein 0.0135 0.0351 0.0497
Entamoeba histolytica hypothetical protein 0.0146 0.0387 0.077
Echinococcus multilocularis tm gpcr rhodopsin gpcr rhodopsin superfamily 0.0135 0.0351 0.0348
Onchocerca volvulus 0.0051 0.0098 0.0646
Brugia malayi hypothetical protein 0.0101 0.0249 0.0497
Schistosoma mansoni nuclear receptor nhr-48 0.0025 0.0018 0.0018
Echinococcus multilocularis biogenic amine (5HT) receptor 0.0135 0.0351 0.0348
Loa Loa (eye worm) tubulin beta-4 chain 0.1644 0.4949 0.7052
Toxoplasma gondii Kazal-type serine protease inhibitor domain-containing protein 0.0059 0.0119 0.0228
Leishmania major beta tubulin 0.1644 0.4949 1
Schistosoma mansoni ubiquitin-specific peptidase 8 (C19 family) 0.0037 0.0054 0.0075
Treponema pallidum cell division protein FtsZ 0.041 0.119 1
Trypanosoma cruzi tyrosyl-DNA Phosphodiesterase (Tdp1), putative 0.0066 0.0143 0.022
Mycobacterium tuberculosis Probable 6-phosphofructokinase PfkA (phosphohexokinase) (phosphofructokinase) 0.0112 0.0282 0.2348
Trichomonas vaginalis PIKK family atypical protein kinase 0.0092 0.0222 0.0448
Echinococcus granulosus nuclear receptor 2DBD gamma 0.0059 0.012 0.0184
Mycobacterium tuberculosis Probable reductase 0.022 0.061 0.5113
Leishmania major beta tubulin 0.1644 0.4949 1
Trichomonas vaginalis phosphofructokinase, putative 0.003 0.0033 0.0066
Plasmodium falciparum holo-[acyl-carrier-protein] synthase, putative 0.0023 0.001 0.0007
Loa Loa (eye worm) hypothetical protein 0.0752 0.2233 0.3179
Echinococcus granulosus ATP binding cassette subfamily B MDR:TAP 0.0022 0.0006 0.0004
Echinococcus granulosus g-protein coupled receptor 0.0135 0.0351 0.0549
Loa Loa (eye worm) hypothetical protein 0.0238 0.0666 0.0945
Leishmania major trypanothione reductase 0.0096 0.0234 0.0461
Echinococcus granulosus ATP binding cassette subfamily B MDR:TAP 0.0022 0.0006 0.0004
Mycobacterium tuberculosis Probable transmembrane multidrug efflux pump 0.0022 0.0006 0.0029
Loa Loa (eye worm) hypothetical protein 0.0664 0.1965 0.2798
Loa Loa (eye worm) hypothetical protein 0.0034 0.0043 0.0058
Echinococcus granulosus ubiquitin carboxyl terminal hydrolase 8 0.0037 0.0054 0.008
Plasmodium falciparum tubulin epsilon chain, putative 0.0938 0.2799 0.5649
Echinococcus multilocularis ATP binding cassette subfamily B (MDR:TAP) 0.0022 0.0006 0.0003
Mycobacterium tuberculosis Probable nitrite reductase [NAD(P)H] large subunit [FAD flavoprotein] NirB 0.022 0.061 0.5113
Brugia malayi sodium-independent organic anion transporter family protein 0.0086 0.0202 0.0402
Mycobacterium ulcerans aldehyde dehydrogenase 0.0062 0.0128 0.1056
Loa Loa (eye worm) hypothetical protein 0.0135 0.0351 0.0497
Schistosoma mansoni tubulin subunit epsilon 0.0938 0.2799 0.441
Trypanosoma brucei phosphatidylinositol 3-kinase, putative 0.0031 0.0035 0.0051
Chlamydia trachomatis endonuclease IV 0.0078 0.0177 1
Leishmania major 2-oxoglutarate dehydrogenase, e3 component, lipoamidedehydrogenase-like protein 0.0033 0.0042 0.0073
Loa Loa (eye worm) hypothetical protein 0.0025 0.0018 0.0021
Schistosoma mansoni photoreceptor-specific nuclear receptor related 0.0059 0.012 0.018
Trichomonas vaginalis PIKK family atypical protein kinase 0.0069 0.015 0.0302
Echinococcus granulosus somatostatin receptor 0.0135 0.0351 0.0549
Schistosoma mansoni smad 0.0041 0.0066 0.0094
Brugia malayi MH1 domain containing protein 0.0023 0.001 0.0014
Echinococcus granulosus jun protein 0.0171 0.0462 0.0723
Onchocerca volvulus Protein ultraspiracle homolog 0.0059 0.012 0.0803
Trichomonas vaginalis chromodomain helicase DNA binding protein, putative 0.0019 0.000000000036275 0.000000000073297
Loa Loa (eye worm) hypothetical protein 0.0078 0.0177 0.0249
Toxoplasma gondii LsmAD domain-containing protein 0.0103 0.0253 0.05
Mycobacterium leprae conserved hypothetical protein 0.0023 0.001 0.0057
Echinococcus granulosus tubulin alpha chain 0.1253 0.3759 0.5929
Echinococcus multilocularis growth hormone secretagogue receptor type 1 0.0135 0.0351 0.0348
Leishmania major beta tubulin 0.1644 0.4949 1
Plasmodium falciparum LCCL domain-containing protein 0.0101 0.0249 0.049
Brugia malayi bZIP transcription factor family protein 0.0171 0.0462 0.0927
Toxoplasma gondii histone lysine methyltransferase SET/SUV39 0.0063 0.0133 0.0256
Schistosoma mansoni TGF-beta signal transducer Smad2 0.0041 0.0066 0.0094
Toxoplasma gondii ATP-dependent DNA helicase, RecQ family protein 0.0024 0.0015 0.0017
Trypanosoma cruzi PAB1-binding protein , putative 0.0103 0.0253 0.0445
Echinococcus granulosus neuropeptide FF receptor 2 0.0135 0.0351 0.0549
Plasmodium falciparum dihydrolipoyl dehydrogenase, apicoplast 0.0033 0.0042 0.0073
Mycobacterium ulcerans aldehyde dehydrogenase 0.0062 0.0128 0.1056
Loa Loa (eye worm) hypothetical protein 0.1253 0.3759 0.5355
Trichomonas vaginalis tubulin, putative 0.0501 0.1467 0.2963
Loa Loa (eye worm) neuropeptide F receptor 0.0135 0.0351 0.0497
Trypanosoma brucei epsilon tubulin 0.0938 0.2799 0.5646
Schistosoma mansoni peptide (FMRFamide/somatostatin)-like receptor 0.0135 0.0351 0.0545
Echinococcus granulosus mitogen activated protein kinase 3 0.0103 0.0256 0.0398
Chlamydia trachomatis fructose-6-phosphate phosphotransferase 0.003 0.0033 0.1545
Onchocerca volvulus 0.0135 0.0351 0.2379
Trichomonas vaginalis conserved hypothetical protein 0.0051 0.0098 0.0197
Loa Loa (eye worm) hypothetical protein 0.0135 0.0351 0.0497
Loa Loa (eye worm) hypothetical protein 0.2322 0.7017 1
Giardia lamblia Fructose-bisphosphate aldolase 0.0283 0.0804 0.1575
Schistosoma mansoni hypothetical protein 0.0135 0.0351 0.0545
Schistosoma mansoni Smad4 0.0041 0.0066 0.0094
Loa Loa (eye worm) hypothetical protein 0.0135 0.0351 0.0497
Toxoplasma gondii Kazal-type serine protease inhibitor domain-containing protein 0.0059 0.0119 0.0228
Onchocerca volvulus 0.0135 0.0351 0.2379
Echinococcus granulosus TGF beta signal transducer SmadC 0.0041 0.0066 0.0098
Brugia malayi G-protein coupled receptor 0.0135 0.0351 0.0704
Plasmodium falciparum ataxin-2 like protein, putative 0.0103 0.0253 0.05
Trichomonas vaginalis PIKK family atypical protein kinase 0.0055 0.0109 0.0219
Loa Loa (eye worm) cytochrome P450 family protein 0.0053 0.0103 0.0142
Plasmodium vivax ataxin-2 like protein, putative 0.0103 0.0253 0.05
Schistosoma mansoni hypothetical protein 0.069 0.2043 0.3217
Echinococcus multilocularis mixed lineage leukemia protein mll 0.0024 0.0013 0.0009
Trichomonas vaginalis conserved hypothetical protein 0.0025 0.0016 0.0032
Schistosoma mansoni serine/threonine protein kinase 0.0026 0.0019 0.0019
Schistosoma mansoni tubulin subunit beta 0.041 0.119 0.1869
Brugia malayi nuclear hormone receptor family member nhr-6 0.0025 0.0018 0.003
Echinococcus multilocularis rhodopsin orphan GPCR 0.0135 0.0351 0.0348
Brugia malayi alpha keto acid dehydrogenase complex, E3 component, lipoamide dehydrogenase 0.0025 0.0015 0.0025
Brugia malayi steroid hormone receptor 0.0059 0.012 0.0238
Schistosoma mansoni retinoid-x-receptor (RXR) 0.0034 0.0043 0.0059
Brugia malayi Tubulin alpha-2 chain 0.1253 0.3759 0.7594
Brugia malayi Phosphatidylinositol 3- and 4-kinase family protein 0.0092 0.0222 0.0442
Leishmania major ATP-dependent phosphofructokinase 0.0112 0.0282 0.0557
Schistosoma mansoni tubulin subunit beta 0.1644 0.4949 0.7808
Trichomonas vaginalis tubulin gamma chain, putative 0.0938 0.2799 0.5655
Loa Loa (eye worm) hypothetical protein 0.0025 0.0016 0.0018
Echinococcus multilocularis lamin dm0 0.0082 0.0191 0.0188
Loa Loa (eye worm) hypothetical protein 0.0135 0.0351 0.0497
Trypanosoma brucei zeta tubulin 0.0695 0.2059 0.4148
Echinococcus multilocularis follistatin 0.0059 0.0119 0.0115
Brugia malayi cytoplasmic intermediate filament protein 0.0044 0.0075 0.0145
Trichomonas vaginalis abcb9, putative 0.0022 0.0006 0.0013
Loa Loa (eye worm) hypothetical protein 0.0135 0.0351 0.0497
Brugia malayi ATP-dependent DNA helicase, RecQ family protein 0.0029 0.0029 0.0052
Echinococcus granulosus tm gpcr rhodopsin 0.0135 0.0351 0.0549
Trichomonas vaginalis PIKK family atypical protein kinase 0.0079 0.0181 0.0365
Echinococcus granulosus Tubulin alpha 1 chain 0.1253 0.3759 0.5929
Loa Loa (eye worm) tubulin alpha chain 0.1253 0.3759 0.5355
Echinococcus granulosus cpg binding protein 0.0091 0.0217 0.0337
Schistosoma mansoni regulator of G protein signaling 0.0025 0.0016 0.0015
Echinococcus granulosus Niemann Pick C1 protein 0.0199 0.0547 0.0857
Plasmodium falciparum tubulin beta chain 0.1644 0.4949 1
Brugia malayi neuropeptide F receptor 0.0135 0.0351 0.0704
Mycobacterium tuberculosis Putative ferredoxin reductase 0.022 0.061 0.5113
Onchocerca volvulus 0.0135 0.0351 0.2379
Trichomonas vaginalis phosphofructokinase, putative 0.0112 0.0282 0.0569
Echinococcus granulosus arachidonate 5 lipoxygenase 0.0412 0.1195 0.1881
Trypanosoma cruzi tubulin delta chain 0.058 0.1709 0.3407
Brugia malayi G-protein-linked acetylcholine receptor protein 2, putative 0.0135 0.0351 0.0704
Echinococcus multilocularis musashi 0.0082 0.0191 0.0188
Trichomonas vaginalis chromodomain helicase DNA binding protein, putative 0.0019 0.000000000036275 0.000000000073297
Leishmania major phosphopantetheinyl transferase-like protein 0.0023 0.001 0.0007
Onchocerca volvulus 0.0135 0.0351 0.2379
Trichomonas vaginalis PIKK family atypical protein kinase 0.0055 0.0107 0.0216
Echinococcus granulosus aryl hydrocarbon receptor 0.0051 0.0098 0.0148
Brugia malayi hypothetical protein 0.0135 0.0351 0.0704
Brugia malayi glutathione reductase 0.0096 0.0234 0.0467
Trichomonas vaginalis tubulin alpha chain, putative 0.0501 0.1467 0.2963
Leishmania major aldehyde dehydrogenase, mitochondrial precursor 0.0062 0.0128 0.0247
Loa Loa (eye worm) hypothetical protein 0.0059 0.012 0.0168
Leishmania major ATP-dependent DEAD/H DNA helicase recQ, putative 0.0031 0.0037 0.0061
Schistosoma mansoni hypothetical protein 0.0101 0.0249 0.0383
Schistosoma mansoni histamine h1 receptor 0.0135 0.0351 0.0545
Brugia malayi hypothetical protein 0.0135 0.0351 0.0704
Echinococcus granulosus Tubulin beta 2C chain 0.1644 0.4949 0.7808
Brugia malayi Steroid receptor seven-up type 2 0.0059 0.012 0.0238
Trichomonas vaginalis PIKK family atypical protein kinase 0.0092 0.0222 0.0448
Echinococcus multilocularis g-protein coupled receptor 0.0135 0.0351 0.0348
Loa Loa (eye worm) hypothetical protein 0.0086 0.0202 0.0283
Loa Loa (eye worm) hypothetical protein 0.0135 0.0351 0.0497
Toxoplasma gondii Kazal-type serine protease inhibitor domain-containing protein 0.0059 0.0119 0.0228
Entamoeba histolytica Niemann-Pick C1 protein, putative 0.0199 0.0547 0.1093
Onchocerca volvulus Huntingtin homolog 0.0249 0.0701 0.4766
Brugia malayi Isocitrate dehydrogenase 0.0032 0.0038 0.0071
Trichomonas vaginalis chromodomain-helicase-DNA-binding protein, putative 0.0019 0.000000000036275 0.000000000073297
Onchocerca volvulus 0.0135 0.0351 0.2379
Echinococcus multilocularis isocitrate dehydrogenase 2 (NADP+) 0.0032 0.0038 0.0034
Trypanosoma cruzi epsilon tubulin, putative 0.0938 0.2799 0.5624
Plasmodium vivax thioredoxin reductase, putative 0.0096 0.0234 0.0461
Echinococcus multilocularis tumor protein p63 0.1033 0.3089 0.3086
Giardia lamblia Gamma tubulin 0.0938 0.28 0.5632
Loa Loa (eye worm) hypothetical protein 0.0199 0.0547 0.0775
Onchocerca volvulus 0.0135 0.0351 0.2379
Trichomonas vaginalis fructose-bisphosphate aldolase, putative 0.0283 0.0804 0.1624
Echinococcus granulosus tubulin alpha chain 0.1253 0.3759 0.5929
Trypanosoma brucei target of rapamycin kinase 3, putative 0.0073 0.0164 0.0313
Trichomonas vaginalis phosphofructokinase, putative 0.0112 0.0282 0.0569
Trichomonas vaginalis tubulin beta chain, putative 0.1253 0.3759 0.7595
Brugia malayi RE15519p 0.0135 0.0351 0.0704
Loa Loa (eye worm) tubulin beta-2A chain 0.1644 0.4949 0.7052
Brugia malayi Phosphatidylinositol 3- and 4-kinase family protein 0.0031 0.0035 0.0065
Trichomonas vaginalis phosphofructokinase, putative 0.003 0.0033 0.0066
Giardia lamblia Alpha-tubulin 0.1253 0.3759 0.7581
Echinococcus granulosus intermediate filament protein 0.0082 0.0191 0.0296
Trypanosoma brucei beta tubulin 0.1644 0.4949 1
Brugia malayi MH2 domain containing protein 0.0602 0.1774 0.3581
Loa Loa (eye worm) hypothetical protein 0.0038 0.0057 0.0077
Giardia lamblia Delta tubulin 0.041 0.119 0.236
Loa Loa (eye worm) hypothetical protein 0.0166 0.0447 0.0633
Echinococcus granulosus FTZ F1 nuclear receptor protein 0.0059 0.012 0.0184
Echinococcus multilocularis neuropeptide Y receptor 0.0135 0.0351 0.0348
Echinococcus granulosus Smad4 0.0041 0.0066 0.0098
Echinococcus granulosus Ataxin 2 N terminaldomain containing protein 0.0046 0.0081 0.0122
Loa Loa (eye worm) CXXC zinc finger family protein 0.0086 0.0202 0.0284
Echinococcus multilocularis ATP binding cassette subfamily B (MDR:TAP) 0.0022 0.0006 0.0003
Brugia malayi Doublecortin family protein 0.0101 0.0249 0.0497
Onchocerca volvulus 0.0101 0.0249 0.1678
Trichomonas vaginalis ATP-binding cassette transporter, putative 0.0022 0.0006 0.0013
Trichomonas vaginalis mercuric reductase, putative 0.0033 0.0042 0.0086
Giardia lamblia Epsilon tubulin 0.0437 0.1273 0.2528
Echinococcus granulosus growth hormone secretagogue receptor type 1 0.0135 0.0351 0.0549
Schistosoma mansoni NADP-specific isocitrate dehydrogenase 0.0032 0.0038 0.005
Echinococcus multilocularis ubiquitin carboxyl terminal hydrolase 8 0.0037 0.0054 0.005
Echinococcus granulosus 5'partial|histone lysine N methyltransferase SETDB2 0.0059 0.012 0.0184
Schistosoma mansoni tubulin subunit alpha 0.1253 0.3759 0.5928
Trypanosoma cruzi tyrosyl-DNA Phosphodiesterase (Tdp1), putative 0.0066 0.0143 0.022
Plasmodium vivax tubulin alpha chain, putative 0.1253 0.3759 0.7592
Echinococcus multilocularis tubulin delta chain 0.041 0.119 0.1186
Loa Loa (eye worm) hypothetical protein 0.0059 0.012 0.0168
Trypanosoma cruzi dihydrolipoyl dehydrogenase, putative 0.0033 0.0042 0.0015
Schistosoma mansoni biogenic amine (5HT) receptor 0.0135 0.0351 0.0545
Brugia malayi ERG2 and Sigma1 receptor like protein 0.0782 0.2325 0.4694
Trypanosoma cruzi epsilon tubulin, putative 0.0938 0.2799 0.5624
Loa Loa (eye worm) sodium-independent organic anion transporter 0.0086 0.0202 0.0283
Trypanosoma brucei isocitrate dehydrogenase [NADP], mitochondrial precursor, putative 0.0032 0.0038 0.0057
Trichomonas vaginalis PIKK family atypical protein kinase 0.0069 0.015 0.0302
Leishmania major beta tubulin 0.1644 0.4949 1
Schistosoma mansoni steroid hormone receptor ad4bp 0.0059 0.012 0.018
Loa Loa (eye worm) tubulin alpha 2 0.0342 0.0984 0.1399

Activities

Activity type Activity value Assay description Source Reference
Ki (binding) = 15 nM Displacement of [125I]-AB MECA from recombinant human adenosine A3 receptor expressed in HEK cells ChEMBL. 15341491
Ki (binding) > 4000 nM Displacement of [3H]-CCPA from recombinant human adenosine A1 receptor expressed in CHO cells ChEMBL. 15341491
Ki (binding) > 5000 nM Displacement of [3H]-CGS-21,680 from recombinant human adenosine A2a receptor expressed in HEK cells ChEMBL. 15341491
Selectivity (binding) > 200 Ratio of binding to adenosine A1 and adenosine A3 receptor ChEMBL. 15341491
Selectivity (binding) > 300 Ratio of binding to adenosine A2a and adenosine A3 receptor ChEMBL. 15341491

Phenotypes

Whole-cell/tissue/organism interactions

We have no records of whole-cell/tissue assays done with this compound What does this mean?

Many chemical entities in TDR Targets come from high-throughput screenings with whole cells or tissue samples, and not all assayed compounds have been tested against a single a single target protein, probably because they get ruled out during screening process. Even if these compounds may have not been of interest in the original screening, they may come as interesting leads for other screening assays. Furthermore, we may be able to propose drug-target associations using chemical similarities and network patterns.

Annotated phenotypes:

We have no manually annotated phenotypes for this drug. What does this mean? / Care to help?
In TDR Targets, information about phenotypes that are caused by drugs, or by genetic manipulation of cells (e.g. gene knockouts or knockdowns) is manually curated from the literature. These descriptions help to describe the potential of the target for drug development. If no information is available for this gene or if the information is incomplete, this may mean that i) the papers containing this information either appeared after the curation effort for this organism was carried out or they were inadvertently missed by curators; or that ii) the curation effort for this organism has not yet started.
 
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External resources for this compound

Bibliographic References

1 literature reference was collected for this gene.

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